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Coach Gladden Honored To Be Derrick's Guest
Updated: 07/24/2014 - Jim Gladden joined us live on set to talk about Derrick Brooks
Updated: 07/24/2014 - Jim Gladden joined us live on set to talk about Derrick Brooks
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Posted: 07/18/2014 - The sophomore midfielder is one of 21 players to play for the U.S. at the 2014 U-20 World Cup in Canada beginning August 5.
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Posted: 07/18/2014 - Leon continues to upgrade the facilities within their football program.
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Updated: 07/14/2014 - Jameis Winston and the Florida State football team are ESPYS nominees
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Posted: 07/12/2014 - Former FSU Outfielder James Ramsey made the 2014 Futures Game Roster, an all-star game of the top minor league players.
Posted: 07/11/2014 - The 2014 Jim Thorpe Award Preseason Watch List features FSU defensive backs Jalen Ramsey and P.J. Williams
Updated: 07/11/2014 - LeBron James is going back to the Cleveland Cavaliers after spending the past four seasons with the Miami Heat.
Updated: 07/10/2014 - Mario Edwards, Jr., P.J. Williams, Cameron Erving, Tre' Jackson and Josue Matias added to growing list of FSU summertime accolades
Posted: 07/10/2014 - The Bulldogs start the season at home in Sanford Stadium versus Clemson on August 30.
Updated: 07/10/2014 - Strall was 7-2 at TCC in 20104
Updated: 07/10/2014 - Posey Named Coach Of The Year

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90 Blood Elf Priest
I did it for the first time the other night and it was ugly.
I'm having alot of trouble with Feng the Accursed and was the main reason our group wiped a half dozen times with him. Some of it I learned by trial and error, but others I can't figure out.
Edited by Nallely on 2/12/2013 12:40 PM PST
90 Gnome Priest
If I remember correctly he does the earth phase first. That's where a lot of damage starts to happen. The AoE is called Epicenter, he smashes the ground and causes damage to everyone. There is a barrier ( I'm not sure what its called, but its pretty & blue! ) it will happen every other turn. ( Its a gem that a tank should pick up, it will spawn when you pull feng on the right side of the room )
So lets say you use the blue barrier for the first epicenter, SS for second, blue barrier third, and priest barrier fourth, etc.
The second phase should be fire, SS should be used when he draws in the fire for Draw Flame. Also I think ( do not quote me on this ) that if you use the barrier every other time, it will cancel out his draw flame.
And then comes arcane ( yay, smiles ) things get pretty intense. Arcane velocity is the great time for SS. It causes the aoe raid damage, and stacking up can help. Do note that do NOT let the person who is exploding everywhere stack. Have them use a personal CD, or you'll just have to heal them through it. Also note, that sometimes timing can be out of whack, and during stacking ( if you decided to do so ) that someone CAN start exploding in the raid. One must move away.
Edit: I forgot to note that the blue barrier will also work on arcane. You can use the same rotation for this as epicenter.
Edited by Valarina on 2/12/2013 12:50 PM PST
For Draw Flame (when he sucks in the wildfire and starts pulsing aoe) you should only have to heal one of those, the others should be canceled with barrier. Wait until he sucks in the flames, then pop cds and roll SS on the raid. Ideally you'll get 1 cast of PoH on each group before the pulsing starts. Don't forget PoM and Cascade.
PW: Barrier is useful for epicenters that get through and for un-bubbled Arcane Velocity in the final phase (which you should also Spirit Shell. If you start just after the bubbled Velocity it will be stacked for the unmitigated one).
As always make sure you're on the same page with your co-healer regarding cds.
Think you were being scape goated tbh. Sounds like a tanking problem as those abilities can be interrupted every time. One tank can stun one and the other throws up the barrier to absorb it on the second. Even if you miss one you just have to heal through it.
I would suggest pw:b on arcane volocity. Everyone should be running in to stack on the boss at that point.
90 Draenei Shaman
Absolutely this. Feng is a tank fight. They each get a special ability at the start of the fight; one gets a spellsteal ability which the tank then uses on Feng when he's casting Lightning Fist. The tank then uses the stolen ability to interrupt Epicenters. It can be tricky timing for a tank to learn, and there will sometimes be Lightning Fists that the tank's spellsteal ability is on cooldown for
meanwhile the other tank gets an ability which puts up the deep blue PW:B-like dome the others have spoken about here. That ability mitigates most of the damage of the Epicenters it's used on (but you have to get under the dome for it to shield you, and it doesn't last the entire duration of Epicenter so some of the damage *has*to be taken), but it also has a cooldown and cannot catch every Epicenter.
Ideally what happens is the tank who spellsteals will interrupt an Epicenter, and then the tank with the blue dome will shield the next Epicenter, and then by the time Feng's doing his 3rd Epicenter the spellstolen interrupt is usually available again (... if the tank's done his job right...).
P2 only the blue dome works. It can catch every other Draw Flame (and negates it). If everyone who gets a Wildfire Spark runs to a predetermined far-away spot to plant it, then the Wildfire only gets drawn "from" one place and when the tank's blue dome isn't available, everyone can avoid the incoming Wildfire fairly easily. If you get caught in the Wildfire, I think it gives Feng a buff for every second you stand in it or something, so it's worse than "just taking damage standing in the bad".
P3 only the dome works. And yes, the tank absolutely should use it (can cover every 2nd time he does his huge P3 AoE damage move). Meanwhile, he will target random ranged players (no matter where they're standing) for Arcane Resonance and as Sadie says, if you get it you must run far enough away so that the pale purple circle (thanks Blizz, yeah, that's easy to see with all the arcane sparkly stuff everywhere...) doesn't touch anyone. It will literally blow up your raid if someone gets it and doesn't move away fast.
You'll get him next time ;D Knowledge is power.
100 Human Priest
Anything I have to say: http://us.battle.net/wow/en/forum/topic/6794980143
But the tank with null barrier can prevent the draw flame from landing on Feng if he uses it on top of the boss. The null barrier can also prevent all damage from an epicenter and arcane storm if everyone is underneath it. The other tank can use their shroud of reversal on a target that is going to be stunned by lightning fists, and then use the stun to interrupt an epicenter.
90 Draenei Paladin
Feng does lightning fists/epicenter first. Then he does spark/draw flame. Lastly, he does resonance/velocity.
The first phase it's very important for the tanks to manage the fists/epicenter. If they don't steal the fists there'll be an epicenter in which case melee need to run to center where range should be stacked and if the barrier is up, use it for all (if healing is rough this is the ideal method, if healers feel good, the barrier can go up in melee group). AoE heal through it. In low level gear you can manage one, maybe two mess ups with fists/epicenter, more than that and you'll find yourselves oom by 3rd phase.
During second phase he'll cast wildfire spark and it's best to have whomever gets this run either left or right out of the group. This way when he does draw flame, the flames won't hit the raid and give him the stacks that does the very painful raid damage. We found ourselves using hero for this phase as the flame damage was really giving us issues even with avoiding unnecessary stacks. We really had to minimize the time spent in this phase. If you can swing it, use the barrier on the 1st and 3rd. You don't want to have that 4th draw flame. You do NOT want those flames hitting players as he draws them in as it causes him to gain more stacks which equals a lot more damage.
During third phase it's very important to watch DBM timers. You must be I think 6 yards apart. When he casts velocity everyone should stack except the player with resonance. Pop your AoE heals (your spirit shells) and key here is clipping velocity and getting out right at the tail end because he'll cast a resonance often right as velocity ends and if a player is slow to move, he'll blow up the raid. Resonance hurts. So key here is don't stay too far back as you really must get in to Feng quickly with velocity but you must get out a hair before velocity ends because resonance cast right as it ends can often cause a player to inadvertently blow up the raid.
This fight isn't simply a tank fight. It really requires all members of the raid to be on their toes. But if the tanks do not do their job right, the fight will most likely end in a wipe.
Good luck!
100 Tauren Druid
Definitely gets easier. On our first Feng kills, we had to rotate through healing cooldowns. We'd 3-heal, and everyone had their turn for a raid-healing CD.
Now someone might use a Tranq, but we're 2-healing, and having a grand old time of it.
90 Gnome Monk
To answer one question you asked that no one answered, the draw flame happens after 3 players get wildfire sparks (I think that's the name anyway). If all goes according to plan you will only have to heal through one of them.
90 Blood Elf Priest
One thing to keep in mind... where are your raiders dropping off the wildfire? Once it's drawn into the boss, it's possible for people to stand between the path of the fire and the boss. They'll take damage as if they were standing in the fire. That makes the healer a lot harder.
Otherwise, as others have indicated, using the Nullification Barrier on Feng will prevent the wildfire stacks. That way you'll have a phase of nothing.
For Barrier, how are your people positioned? If you have a range heavy comp stacking in the center, then you can use it early in the fight for an Epicenter. It will be up again when you can use it for an Arcane Explosion that he does, when everyone is supposed to run in. Of course, you want to time it so your tank doesn't also use a Nullification Barrier as well.
90 Human Priest
Use your hymn, always works in tight situations
100 Worgen Druid
I'm having alot of trouble with Feng the Accursed and was the main reason our group wiped a half dozen times with him. Some of it I learned by trial and error, but others I can't figure out.
I'm guessing you're talking about Draw Flame. What happens is that he sucks all the fire patches on the floor into him, and he gains 1 stack of buff for each one that reaches him. Then , each melee attack he does thereafter, 1 stack of buff is consumed and does a large amount of raid damage. You can see his stack count by looking in his buffs area.
Every second Draw Flame will able to be Nullified by one of the tanks (assuming he does it correctly), but you'll have to heal through the rest.
I'd advise using Time Warp on this phase so you can make sure you only have to heal one phase (i.e. barrier 1st and 3rd, and TW+healing CDs for second). If your group has high DPS you could keep it to just two Draw Flames which is even better.
It's important you don't go into Phase 3 with the boss still buffed, so if your raid messes up on the last Draw Flame then the leader should call a STOP DPS until the boss's buff has expired.
The raid should be stacked for this phase so that you can use things like PW:B and get the most out of AOE healing.
I felt like I was thrown into the lions den due to not knowing all of the ability mechanics. Any help?
Run the fight on LFR so you get a basic idea what's going on. Then read the Dungeon Journal and a third-party encounter guide to fill in the gaps in your knowledge about all the mechanics.
100 Blood Elf Mage
She's disc.
I think everyone has given some great advise, and they are correct that tanks doing their job makes this fight much easier. Usually on P1, I use spirit shell on the epicenter the tank is using the nullify dome on (starting the spirit shell about 10 seconds before epicenter). There's usually just enough damage until the dome goes up that it makes it worthwhile. The one that's interrupted we never see any damage.
On P2 I use spirit shell on the draw flames that the tank is not using the dome on. Keep in mind that after the boss actually draws the flame, it takes a couple seconds for the wildfire to reach the boss, so I try to start spirit shell about 5-7 seconds before draw flame.
On P3, the arcane velocity is the big damage. Like P2, I use spirit shell on whichever velocities the tank is not using the dome. People take less damage if they're close to the boss, so everyone should be gathered, and this also makes a good time to use barrier. One of the hardest things I found about P3 is making sure the raid as a whole is scattering as soon as arcane velocity ends. (Arcane resonance can be cast right after velocity and it does much more damage if people are bunched up.)
Just a general note, usually damage is low enough between the high bursts that it's perfect for atonement, which means archangel is usually up for the high burst damage periods.
Disc is incredible on this fight. Really it's all up to the tanks to a; Do their job
and b; Most importantly communicate. A priest needs to know asap whether a mechanic was missed so he can ramp up SS.
O!@#$s can happen, specially with new groups/pug tanks. But they're easily healed through if you have a headup, which you always should have from the tank.
Edited by Tonydanza on 2/16/2013 10:53 AM PST
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When a Man You Love Was Abused
A Woman's Guide to Helping Him Overcome Childhood Sexual Molestation
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When I'm hangin' out drinking in the back of an El Camino
from Sum 41 – Fat Lip Lyrics on Genius
An El Camino is an iconic vehicle of Southern Redneck culture. Drinking in the back is thought to be the epitome of white trashiness. This is very poserish because Sum 41 is from Ajax, Ontario, a very middle class suburb.
Sweet ride, bruh.
To help improve the quality of the lyrics, visit Sum 41 – Fat Lip Lyrics and leave a suggestion at the bottom of the page


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Through providing exceptional customer buying experiences and top quality products, Deerfoot Carpet and Flooring has been serving Calgary for over 20 years!
Deerfoot Carpet & Flooring always has great pricing, on most flooring products in the market today. Our volume buying allows us to provide the best priced products available in the city, whenever you need it!
Our goal as a family owned local business is to provide the community with amazing products and guaranteed service. We are always striving to create another happy Deerfoot customer!


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Things I Want My Daughters to Know
By Elizabeth Noble
(William Morrow Paperbacks, Paperback, 9780061686597, 400pp.)
Publication Date: February 2009
Other Editions of This Title: Hardcover, Paperback, Paperback
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How do you cope in a world without your mother?
When Barbara realizes time is running out, she writes letters to her four daughters, aware that they'll be facing the trials and triumphs of life without her at their side. But how can she leave them when they still have so much growing up to do?
Take Lisa, in her midthirties but incapable of making a commitment; or Jennifer, trapped in a stale marriage and buttoned up so tight she could burst. Twentysomething Amanda, the traveler, has always distanced herself from the rest of the family; and then there's Hannah, a teenage girl on the verge of womanhood about to be parted from the mother she adores.
But by drawing on the wisdom in Barbara's letters, the girls might just find a way to cope with their loss. And in coming to terms with their bereavement, can they also set themselves free to enjoy their lives with all the passion and love each deserves?
This heartfelt novel by bestselling author Elizabeth Noble celebrates family, friends . . . and the glorious, endless possibilities of life.
Elizabeth Noble is the author of the internationally bestselling novels The Reading Group, The Friendship Test, and Alphabet Weekends. She lives with her husband and their two daughters in New York City.
- What would you say in a letter to your daughter? What advice would you give?


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SYNOPSIS: After crashing off the coast, Lt. Brian Murphy battles for survival across the vast terrains of Africa in search for a way to get back to his beloved family. Joined by local military man Daniel Dembele who is also searching for his son, together both men join forces all the while battling against the ever present threat of the living dead! REVIEW: Lt. Brian Murphy (Rob Bowman) is just trying to get home. His … Continue reading


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"The History of Elizabeth's Merchant Adventurers"
A learned yet fascinating look at what Elizabeth I had to do to defeat Philip II of Spain. (Remember the Spanish Armada?) It's about the economy and the role her "explorers" played. Lots on John Hawkins, Francis Drake, and Walter Raleigh. It's a scholarly book yet it's a pretty good story. It's full of facts and figures, so it's nice to have the book nearby. It's a wonderful way to learn history. A bodice ripper, it isn't. Elizabeth was more than just a romantic figure, she was a cagey monarch. This book tells the story of the men she used to achieve her economic and political ends.
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Macy Osborne Model
cary fixePhotographer Male New York, New York, US
My Website: fIXE MagazineMy MM URL: http://www.modelmayhem.com/cary
Mayhem # 416302
About Me
I'm the publisher of www.fixemagazine.com an online publication that presents Fetish, Pinup and other Alternative material in a mainstream and accessible way. My over simplified description is, "Like Maxim, but kinky"
I'm looking to shoot again now after a looooong hiatus. Took some pix of my cats, they got bored, ready to move up to humans
Also just so you know, I'm not charging for photos, nor do I want to be charged at this point. So TFP, Trade, whatever the kids are calling it these days, that's how I would like to do things.
This is me, in case you were wondering for some reason...
Publisher of fIXE Magazine http://www.fixemagazine.com
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Properties in Little Tarrington, Hereford, Herefordshire And Worcestershire between £1 and £10,000
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£695 per month Let Agreed 2 Bedrooms Little Tarrington, Herefordshire
A spacious two bedroom barn conversion built to a very high standard and boasting all of the modern day essentials, communal garden and ample off road parking located in rural Herefordshire with good road communications to Hereford and
£750 per month Let Agreed 3 Bedrooms The Drive, Little Tarrington, Hereford
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Two Shot, Killed in Ky. College Parking Lot
Members of the Perry County Sheriff Office respond to the scene at Hazard Community College on Tuesday night, Jan. 15, 2012, after a shooting at the school in Hazard, Ky. Authorities say two people were shot and killed and a teen was wounded in the parking lot of the eastern Kentucky community college. (AP Photo/The Ashland Daily Independent, Joshua Ball)
Photo credit: The Associated Press
Hazard Community and Technical College President Dr. Stephen Greiner addresses the media Tuesday, Jan. 15, 2013 following a shooting on campus in Hazard, Ky. Authorities say two people were shot and killed and a teen was wounded in the parking lot of the eastern Kentucky community college. (AP Photo/The Ashland Daily Independent, Joshua Ball)
Photo credit: The Associated Press
HAZARD, Ky. (AP) — A gunman fired into a vehicle, killing a man and a woman and wounding a 12-year-old girl late Tuesday, and police have charged a 21-year-old with murder and attempted murder in the incident, blaming it on a domestic dispute.
The violence in a college parking lot locked down the campus for more than an hour as police searched the two buildings of Hazard Community and Technical College in Hazard, in southeast Kentucky. The campus was closed Wednesday.
Hazard police Chief Minor Allen said Wednesday that Dalton Stidham, 21, was charged with two counts of murder and one count of attempted murder.
Allen said the shooting resulted from a dispute between Stidham and the woman who was killed, 20-year-old Caitlin Cornett.
Allen identified the male victim as Cornett's uncle, Jackie Cornett, 53. He said the wounded girl was Jackie Cornett's daughter. She was in critical condition at noon Wednesday at Kentucky Children's Hospital, said Julie Phillips, a hospital spokeswoman.
Allen said Caitlin Cornett, who was a student at the college, and Stidham had a child together and had met to exchange custody of him. Allen said police are still investigating what led to the shooting.
Caitlin Cornett's sister, Brittany Cornett, told The Lexington Herald-Leader that Stidham and Caitlin Cornett had separated in October after a three-year relationship. Their son is 2 years old.
The boy was not injured in the shooting and was in the custody of social services workers, Brittany Cornett said.
College President Stephen Greiner said that at the time of the shooting, about 30 students were probably on campus. He said college staff responded quickly to the shooting, securing campus buildings to limit the impact.
"Our thoughts and sympathy are with the families of the victims of this tragedy," he said.
Police recovered the weapon, a semiautomatic pistol, at the scene, Allen said.
Jackie and Caitlin Cornett were already deceased when police arrived about 6 p.m., Allen said.
Conor Duff, the college's evening coordinator, said the outbreak of violence was startling.
"Everybody here's been pretty shook up," he said. "This is definitely something people around here are not used to. We have our fair share of problems, but normally this isn't one of them."
Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Chemotherapy Related Anemia in Patients With Non-Myeloid Malignancies
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- How to Read a Study Record
Chemotherapy can often cause anemia in patients with cancer. Anemia is a low number of red blood cells. The symptoms of anemia may include fatigue, dizziness, headache, chest pain, and shortness of breath. Erythropoietin is a hormone made by the kidneys that signals the bone marrow to produce more red blood cells. Recombinant human erythropoietin has been produced in the laboratory and has the same effect as the hormone produced by the body. Use of recombinant human erythropoietin allows the body to produce more red blood cells, possibly eliminating or decreasing your symptoms and the need for a red blood cell transfusion. Recombinant human erythropoietin is FDA approved to treat anemia in cancer patients receiving chemotherapy. This clinical study is investigating the effectiveness of darbepoetin alfa for the treatment of anemia in patients with non-myeloid malignancies who are receiving chemotherapy every three weeks. Darbepoetin alfa is a recombinant erythropoietic protein that stimulates the production of red blood cells. This medication has not been approved to treat cancer patients with anemia, however it has been approved by the FDA to treat chronic renal failure patients with anemia.
Breast Neoplasms
Lung Neoplasms
Multiple Myeloma
Chronic Lymphocytic Leukemia
Drug: darbepoetin alfa
Phase 2
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|A Randomized, Open-Label, Dose-Timing Study of Darbepoetin Alfa Administered Once Every 3 Weeks (Q3W) by Subcutaneous (SC) Injection for Treatment of Anemia in Subjects With Non-Myeloid Malignancies Receiving Multicycle Chemotherapy
|Ages Eligible for Study:
|18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
- Patients with non-myeloid malignancies * Patients receiving at least 12 weeks of chemotherapy on a 3-week cycle schedule * Patients with anemia (hgb >/= 9.0 and </= 11.0 g/dL)
Please refer to this study by its ClinicalTrials.gov identifier: NCT00036023
|Study Director:
Additional Information:
|Responsible Party:
|Global Development Leader, Amgen Inc.
|ClinicalTrials.gov Identifier:
|NCT00036023 History of Changes
|Obsolete Identifiers:
|Other Study ID Numbers:
|Study First Received:
|May 7, 2002
|Last Updated:
|May 7, 2009
|Health Authority:
|United States: Food and Drug Administration
Additional relevant MeSH terms:
Leukemia, Lymphocytic, Chronic, B-Cell
Immune System Diseases
Immunoproliferative Disorders
Leukemia, B-Cell
Leukemia, Lymphoid
Lymphatic Diseases
Lymphoproliferative Disorders
Neoplasms by Histologic Type
Darbepoetin alfa
Hematologic Agents
Pharmacologic Actions
Therapeutic Uses
ClinicalTrials.gov processed this record on March 30, 2015


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Baymont Inn & Suites East Windsor
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Day 2 NYC
Today was in the 40s but still raw and chilly. We walked north today, up Madison and fifth avenue, stopping at a watch store and the Beretta store. We had a great lunch at Lavo on e58. Again, place was jammed with holiday parties but we sat in bar by front window so was great. My truffle fries and bread pudding made with croissants, dark chocolate chunks and caramel sauce ( with a side of vanilla ice cream) were outstandingly delicious! Again, not having ...
Day one NYC
Although above freezing, the day was grey, damp and threatening rain. After a nice breakfast in the small dining room ( pastries, fresh fruit), we bundled up and went to walk. Went south to B & H, window shopping along the way. We had really good lunch at Havana NY, a Cuban restaurant we happened upon on our way back to hotel. After a few hours rest ( we both were still dragging), we headed out to w52 to ...
Travel day
We were supposed to go to NYC on Sunday dec 15 but Jerry had a sinus infection and I was battling a respiratory thing so the hotel graciously allowed us to drop a day. So Monday we decided around 11am to go in spite of not feeling well. We packed quickly and headed to NYC. Road trip was fine until we decide to follow apples navigation and ended up coming through Astoria! Got there about 5pm ...
Closing the circle
... to face with a mountain goat and her baby in South Dakota, swimming in boiling waters in Colorado, waking up in Wonderland and falling asleep unfamiliar... I am forever grateful I was able to experience this. And I think a part of me left a part of my heart on the open ...
People are interesting
I had planned to cross at St Stephen so I could pass by the chocolate factory, but the road actually goes directly to the new crossing and I did not realize I had to take the exit.
Highway 9 was open and clear. The view of the wild blueberry fields in the fall is quite beautiful as all the plants turn bright red.
I drove almost 1,000 Km's today and when I stopped, the ground kept moving.
I had a nice supper of salmon, broccoli ...


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Where are the old P30 archives?
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Where are the old P30 archives?
There was a very active P30 community on Sailnet for several years, if not longer. Messages could be accessed on a bulletin board like this one and they could be sent to your email address. As far as I know, Sailnet took down the email feature a year or so ago and I lost track. Does anyone know if the archives still exist somewhere? There were thousands of postings on a wide variety of P30 issues and ideas. It would be a shame if they were lost.
I sent the same request to Sailnet a week or two ago and did not receive a reply.
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One Piece Color Walk 4 EagleTalk0
4,079pages on
this wiki
this wiki
|Color Walk 4 EAGLE
|Eiichiro Oda
|Publication information
|Release date
|May 4, 2010
|Preceded by
|Color Walk 3 Lion
|Followed by
|Color Walk 5 Shark
The One Piece Color Walk 4 Eagle book contains, in particularly, the Color panels between Chapter 287 and Chapter 391. They are displayed in order of appearance from 28 July 2003 to 13 February 2006.
It also contains 2 pages of sketches about the Water 7 Saga. The book includes an early design of Kaku with other Water 7 characters, also the names of Oharan Clan members revealed.
Cover PollEdit
On page, 87 announced the result of a poll, Oda ask the readers which cover page they want to see in colors. The winning cover is "The Pirate Radio" from Chapter 475.
- Chapter 475 (639 votes)
- Chapter 481 (489)
- Chapter 563 (382)
- Chapter 2 (356)
- Chapter 358 (354)
- Chapter 419 (323)
- Chapter 562 (256)
- Chapter 420 (211)
- Chapter 81 (197)
- Chapter 307 (187)
Monochrome TalkEdit
It provides an interview of Takashi Yanase, the creator of the anime for children Anpanman, by Eiichiro Oda.
Trivia Edit
- Even though on the cover, Brook does showing up in any of the color page reprints. Also, though he's been shown as member of the Straw Hat Pirates, Franky was not at the time when Oda placed him as ally on the cover.


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Official video! 3rd single taken from Lostprophets' chart-topping album 'Liberation Transmission', available through Visible Noise here: http://www.shop.visiblenoise.com/p-85-lostprophets-liberation-transmission.aspx
The band worked with Ryan Smith on the music video for this song. The video was filmed in Los Angeles and is inspired by the 70's mod film Quadrophenia .
The shoes on the cover art are from a competition where fans were asked to take polaroid pictures of their shoes. The winning submissions made the cover.
This is the first music video in which the band openly acknowledged Ilan Rubin as a member, (he is credited the nickname, "Ilan the Yank,") but this is not his first video appearance, for he appeared in both Rooftops and A Town Called Hypocrisy.


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HELP-do I have a leak or is it just evaporation?
It will be 2 weeks on Wednesday since I got water in my pool. The water was brought in by tanker and I know I have 50K gallons. I have been filling the pool with the garden hose for aprox. 3 hrs a day since the day after the water was put in. As of Friday (10 days after initial fill) the water was at the bottom of the tile line. They shut off the skimmers for a few hrs. until the tanker could get here with 4K gallons of water. The tanker filled it to almost the top of the tile line. I keep my water at 87 and the nights have been cooler (50's and 60's). I have seen steam coming off the water at night and in the morning. I have 2 spillovers from my spa that are aways running unless the spa is on and I have 2 bubblers in the sun shelf that are on occasionally. I did have a leak in my slide pipe but that was fixed on Friday before the extra 4K gallons were put in. We did have people over and there was a lot of diving which = water loss. As of right now the water level is about 2" or less from the bottom of the tile line and I know it is supposed to be at least 3". The pool does sit in direct sunlight all day. They are shutting everything off tonight and doing a static bucket test. Do you think it is a leak somewhere or just evaporation? I am so scared that there is a leak under the concrete? How would they find the leak if there is one? I am so ready to cry. This has been the never ending project and I fear that if there is a leak I will never see the end. Thanks....Megan
Deep breath.
The bucket test will tell all, so worry not.
As for company coming over, heck my 2 kids in 2 hours can easily lower my water level and inch with splashing, diving, water guns etc.
As for evaporation alone, I am in the Houston area and end up adding water to my pool once or twice weekly an inch or so at a time, evaporation is big here.
I should add that it was under water test for a long time as well as during the concrete prep and pour. I am hoping that if it is a leak that it is something as simple as a light conduit. We have had NO rain in a long time either. I will be keeping an eye on the bucket (I get up way earlier than the pool company gets here). Thankfully, they are still one the job working on the slide hill and other things so they were here for me to explain everything.
If the bucket test reveals a leak and not simply evaporation, you will need to locate the leak.
There are some great leak detection companies.
By pressuring up the lines and using highly sensitive listening equipment, they can usually pinpoint a leak within a few inches. They can also use dyes around fittings, light fixtures, skimmers, etc.
By getting a close location of the leak, you can minimize the demo needed to repair it.
Hopefully its just evaporation, but if not its not the end of the world. Hang in there.
If you can, peek at any neighbors' pools and see how much theirs is going down. I was all stressed out about my new pool, too, until I started looking around and saw my neighbors were worse than mine (I've been refilling when it gets 1 inch low.)
And the kids use Super Soakers when they play in the pool - water goes everywhere. Then it rained for two days and the overflow couldn't keep up. The water was almost lapping over the coping.
Well, it is a definite leak. The pool water fell 1" in 12 hours and the rate of evaporation of the water in the bucket was only 1/8". The pool builder is also a service company so they are shooting dye into it right now. All the lights are off and they are waiting for the owner of the company to call them back. This is just the icing on the cake. If this was the only thing that went wrong I would be upset but not angry. I am ready to scream.
Really, you should be happy. You found the issue, and have a PB that is making things right.
I have a friend right now that is suing a woodlands TX PB for gross negligence on their build while they were in South America. Everything was done wrong and was caught on hidden cameras. Looks like the are going to demolish and remove the pool.
We think that the leak has been found. They injected the dye into the light conduits and the light under the spa spillover sucked it right up. They ran another bucket test last night after they temporarily sealed the leak and my husband said it does not appear to have lost any more water overnight. They were sending one of their service guys out today to permanently seal all the light conduits. Hopefully, that will take care of everything. I guess it is the best of both worlds because it was an easy fix and if we were losing 1" of water a day to evaporation we would have been in big trouble. I don't mind running my hose a little bit but we are on well so I fear burning it up if I run it too much.


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The event will be held at Mohegan Sun Jan. 27 and 28.
The 2011 Connecticut Turf & Landscape Conference and Trade Show will take place Jan. 27 and 28 and stress "Sustainability for Success."
The conference and show is hosted by the Connecticut Grounds Keepers Association at the Mohegan Sun in Uncasville. The two-day event includes:
• Educational seminars offering recertification credits for owners and operators.
• Tracks for turf or landscape and ornamental.
• Organic methods of management.
• Access to university scholars in the field.
• Networking opportunities with businesses from the region.
• Interaction with vendors offering a full range of products and services.
• Free parking, available lodging and entertainment.
Seminars will be held from 8:30 a.m. – 5 p.m. Thursday, Jan. 27. The tradeshow, along with seminars from 8 a.m. – 4:30 p.m., will be held Friday, Jan. 28. To register for the conference and show, click here. A full list of courses can be found by clicking here.
3032E and 3038E are the newest additions to the compact utility tractor line.
Oxalic acid will target varroa mites, which are a threat to honeybee colonies.
Zero-turn and stand-on mowers get all the attention, but walk-behinds can show your clients you are paying especially close attention to their properties.
Araujo and Lopes have been promoted at the Alexandria Landscape Management branch.
Try these seven search engine optimization quick-fixes for your lawn care and landscaping website.


text: Originally from Chicago, I've been in SF for 13 years now and have started a family here. We love all that the bay area has to offer. I love international travel, great food, wine, snowboarding, volleyball, getting outdoors and dinner parties/BBQs with good friends! These days we are kept busy mostly with toddler activities.


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This is a lovely little bar to sit outside in the sun and have a drink.The Sunday Lunch here is one of, if not the best, in the area.Well worth a visit.
This seems to be a little hidden gem, although it is british cooking, all the same it is excellent prices, portions, food & service. Hope the present owners continue to stay.
Not only Sunday Lunches up to usual standard but also the meals during the week including the bbq first class , keep it up Huw and Carole
After more than 60€ of bill eating and drinking with a dozen of friends the owner refused us to charge our tablet for 5 min... Not one smile or not any friendly signs.... This establishment is not worth it at all. We came for a week and never had any sign of good willing... Run away from it !
Been visiting los nietos for over 6 years now and this is the best bar/restaurant around !, food is excellent, service is very quick and the atmospher is just like no other , genuin and friendly staff will make you feel just at home ! Highly recommend to try the famous Sunday roast as they ARE the best you can...
been to los nietos many times. always had great meals. a really friendly pub owners and staff lovely. definitely going back.
Standard of meals are excellent,at a very reasonable price, Fish and chips,Sunday roast,Liver and bacon all to die for. A big Thank you to Hugh and Carol for making us very welcome. We will definitely be back soon I hope.
Always have had a great time here,food excellent especially the Sunday lunch, staff very friendly and helpful
The previous complaints make me think that they either went to a different restaurant or they have an ulterior motive.
We went for the sunday lunch and its a mishmash. Very odd setup when we called to book we couldn't until 2 weeks later and then we could only have 3pm, but it was half empty (sales man ship or all they can cope with who knows?) Now i have to say the choice of meat was very good and...
nothing but a below average pub empty and dyer looking at a brick wall with nothing in sight to look at apart from passing cars fish and chips were awful and service was rude.
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W.H. Morley and Son Clover Leaf straight razor/razors
- Sold for: Start FREE Trial! or Sign In to see what it's worth.
- Item Category:
- Source: eBay
- Sold Date: Apr 15,2007
- Channel: Online Auction
This razor is in excellent + condition. No cracks or chips in the blade or scales. On the front tang it says W.H. Morley & Sons and has a clover leaf. And says clover leaf brand Germany. On the front scale it has a clover leaf and says clover leaf brand. T is no rust on this one.
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Packaging and Labeling
Latest Headlines
Latest Headlines
Lawsuit would force FDA to ban or label wheat gluten as ingredient
Celiac sufferer Michael Weber is suing the FDA for dragging its feet on a citizen petition he filed in 2008. The lawsuit attempts to force the FDA to either ban gluten from use in drugs or at least require labels to indicate it is an ingredient in prescription and over-the-counter drugs.
Arena, Eisai have to recall nearly 122,000 bottles of Belviq over labeling glitch
Arena Pharmaceuticals has seen sales of its weight-loss drug Belviq improve since teaming up with marketing partner Eisai. But the two have hit a manufacturing stumbling block, having to voluntarily recall three lots of the drug because of labeling issues.
Indian drugmakers lambast proposed PET packaging ban
Indian drugmakers are in a dogfight with Indian regulators who have proposed banning the use of PET plastic bottles for some drug packaging. If they have to move to glass, it will add up to 30% to their transportation cost per bottle, they have complained.
DOJ investigates Dr. Reddy's for failing to protect children with packaging
The drugmaker says it disagrees with the U.S. Consumer Product Safety Commission's allegations and is talking things over with the CPSC. But the Department of Justice is also investigating a complaint related to the same matter under the Federal False Claims Act.
FedEx to fight charges it was key link in supply chain for illegal drugs
After its competitor UPS settled with U.S. authorities over accusations that it was a key link in the supply chain for Internet pharmacies, FedEx vowed to fight any charges that came its way. It will get the chance to do just that after the Justice Department filed charges against the international delivery service.
American Health recalls epilepsy drug and ibuprofen over possible tablet switch
Another company is having to recall products because of packaging issues which could lead to serious health consequences for patients. This time the mix-up could result in patients getting ibuprofen instead of their scheduled dose of a seizure drug presribed for epilepsy patients.
Supplier of unprotected foreign-made cancer drugs gets 15-month prison sentence
Federal authorities have torn down another pillar in a wide-ranging business that sourced foreign-made cancer and other drugs and sold them to U.S. doctors at a discount. Some of the meds were cold-chain drugs that were sometimes left unrefrigerated in Pakistan.
Illinois man pleads guilty to selling $3M worth of foreign Botox
The FDA and Department of Justice have taken down another company that brought foreign-made drugs into the country and sold them to physician practices. They say an Illinois man and his company grossed $3 million in three years, selling Allergan's Botox and Juvederm 2 and 3 that were made for the U.K., and 6 countries in the Middle East.
Boehringer Ingelheim works a deal with Saudi firms to package its products
Boehringer Ingelheim is taking steps toward producing medicine in Saudi Arabia for the local market, striking a deal with two Saudi companies, Cigalah and Tabuk, which will manage and handle secondary packaging projects for 26 Boehringer Ingelheim products.
GSK says someone tampered with alli bottles
Drug tampering not only poses threats to consumers but is also disruptive and expensive for drugmakers. In the latest case, GlaxoSmithKline sent out an alert Wednesday warning that someone has been altering its over-the-counter weight-loss drug alli.


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England's top 20 clubs ever: Liverpool & Man United battle it out for first place, while Chelsea & Man City are way behind
A table has been published by the Daily Mail, revealing the average final league position of every side currently in the Premier League and Football League this season.READ MORE: Premier League Transf... [Read More]
50 biggest clubs in England: The DEFINITIVE list, with Man United, Liverpool & Arsenal battling for top spot
A table has been compiled of the statistically biggest clubs in English football, with a lower score better in terms of adding up average league position, rank for crowd attendance, rank for number of... [Read More]
The date for our FA Cup semi-final against Championship side Reading has finally been announced, with the match set to take place on Saturday, 18 April, at 17:20, as reported by the BBC. READ MORE: ... [Read More]
The Gunners will face Reading on April 18 at the Madejski Stadium as they look to reach their second consecutive Wembley showpiece, while Liverpool or Blackburn face Aston Villa... [Read More]
Transfer gossip: Chelsea close in on Varane, Liverpool hope to open talks with Alves, Dragovic on Arsenal radar plus much more
Friday's news and transfer rumour gossip. Chelsea manager Jose Mourinho has put Real Madrid and France defender Raphael Varane, 21, at the top of his summer transfer targets - (Daily Mirror) Mo... [Read More]
You don't get prizes for leading the league table on Christmas Day, just ask Liverpool, Aston Villa, Leeds and Newcastle. Nonetheless, it's still interesting to look at which clubs have sp... [Read More]
Gossip: Wolfsburg Tell Man U To Wait For De Bruyne, Reds In Race For £18m Pjanic, Gunners To Watch Kiev Defender And Spurs To Meet Rabiot Reps
Wednesday's news and transfer rumour roundup.Wolfsburg boss Dieter Hecking says that Manchester United target Kevin De Bruyne will remain at his current club for at least another season. The 23-... [Read More]
We round up our favourite pictures from Bradford v Reading; Aston Villa v West Brom; Liverpool v Blackburn and Manchester United v Arsenal Continue reading... [Read More]
Arsenal and Liverpool can only meet in the final of the FA Cup – if they both go through to the showpiece event at Wembley. The Gunners will play Reading or Bradford City in the semi-finals, whi... [Read More]
FA Cup Semi Final Draw Preview And Live Streaming: Liverpool, Manchester United, And Arsenal Potentially All Involved
Aston Villa, Blackburn Rovers, Reading, and surprise package Bradford City are the other teams involved in the draw... When: 21.45 GMT 9th March 2015 Where: Old Trafford, Manchester Watch Live h... [Read More]


text: If you struggle with knowing which veggies to eat for the best health possible, then stick to one simple rule – keep it colourful! Colourful fruit and vegetables have a lot of antioxidants and vitamins in them, so makes ure your plate is loaded with colour. Keep it mixed up with orange carrots, green kale and blueberries for desert. The antioxidants will not only make your healthier, but protect your skin too!


text:
Ridley Dean RSSRAM Apex Complete Bike - Road Bike Shop
Road Bike Shop
Product Search Results For "Ridley Dean RS/SRAM Apex Complete Bike"
|Ridley Dean RS 10 Ultegra Complete Road Bike - 2015
In a perfect vacuum, creating the most efficient aerodynamic bicycle would be an easy job. Just make it light and stiff. But since we don't live and ride in a vacuum, questions of aerodynamics must be addressed, and the Ridley Dean RS 10 Complete Road Bike does so in ways that aren't always...
|Ridley Helium RS/SRAM Force Complete Road Bike - 2014
After successfully increasing the Damocles' stiffness and stability, while dramatically reducing its overall weight, Ridley's engineers emerged with what would become known as the Helium. At nearly 300 grams lighter than the Damocles, it's a frame that was bred for the mountains. Not surprisingly...
Price: $4195.00
|Ridley Helium SL 10 SRAM Red 22 Complete Road Bike - 2015
Helium is a noble element, which is the purest, simplest form of matter that you can get without breaking down into subatomic particles. So it's appropriate that, for the Helium SL 10 Complete Road Bike, Ridley opted for a simple, traditional, and proven kit with just a sprinkling of new pieces...


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1047-1099 South Cam De Bravo
Pueblo West, Colorado, 81007
Commute to Downtown Pueblo West
Almost all errands require a car.
Score Details
1047-1099 South Cam De Bravo has a Walk Score of 3 out of 100. This location is a Car-Dependent neighborhood so almost all errands require a car.
This location is in Pueblo West.
Nearby schools include Sky View Middle School, Pueblo West High School and Cedar Ridge Elementary School.
1047-1099 South Cam De Bravo is near Golden Guardian.
Explore how far you can travel by car, bus, bike and foot from 1047-1099 South Cam De Bravo.
View all Pueblo West apartments on a map.
Popular apartment searches include pool and fireplace. View all Pueblo West apartments and rentals.
This location is in the city of Pueblo West, CO. Pueblo West has an average Walk Score of 6 and has 29,637 residents.Learn More About Pueblo West


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C-COR puts up $89.5 million for nCUBE
C-COR Inc. became a high-ranking player in the video-on-demand game literally overnight after striking an $89.5 million deal to acquire nCUBE Corp.
The acquisition automatically positions C-COR as one of cable's "Big Three" suppliers of on-demand servers and software, joining the ranks of SeaChange International and Concurrent Computer Corp.
The deal's total value is comprised of $20 million in cash, $35 million of senior unsecured five-year convertible notes, 4.5 million shares of C-COR common stock, and the assumption of undisclosed liabilities. The companies expect to close the deal in the second quarter of C-COR's 2005 fiscal year.
It's been rumored for months that Larry Ellison would sell nCUBE for the right price as the cable MSO sector continued to consolidate. It is anticipated that Ellison, as a large C-COR shareholder, will sit on the C-COR board. Needham & Company speculated in a research note that losses accrued by nCUBE over the years were a driver in the sale to C-COR.
With nCUBE in the picture, C-COR will find itself with VOD relationships with several major MSOs, including Adelphia Communications, Bresnan Communications, Charter Communications, Mediacom Communications, Shaw Cablesystems and Time Warner Cable.
C-COR said its expects the acquisition to add roughly $50 million in net sales in the 12 months following the closing.
C-COR said it plans to fold the Beaverton, Ore.-based VOD and ad insertion company into its software business unit. nCUBE President and CEO Michael Pohl will stay on to become president of the unit, and operate it out of Beaverton. Doug Engerman, who has been running C-COR's software business, will become COO of the division.
Pohl said the pairing of nCUBE's nABLE platform and C-COR's suite of OSS, network and workforce management software offers a "logical extension of this business."
C-COR's focus on nCUBE's software portfolio has opened up speculation that it will eventually phase out nCUBE's server/hardware business. But C-COR isn't saying when that might happen.
"We will continue to support [nCUBE's hardware] product line," said Ken Wright, C-COR's chief technology officer.
Still, nCUBE's nABLE backoffice package "is a very strategic fit with what we do in the OSS cable space," he added. "nCUBE has developments going on for a next-generation hardware platform for on-demand. They're well down that road. We're not going to just shut that off and walk away from the hardware."
C-COR, Wright added, will also continue to support nCUBE's ad insertion business because it provides a diversification of customers and another revenue stream.
On the VOD front, C-COR will continue the work nCUBE has done in hammering out interops with other server vendors. To date, nCUBE has announced integrations of nABLE with servers from Kasenna Inc. and MidStream Technologies.
"There's a lot more to be written on that," Pohl said, alluding that nCUBE has several others in the pipeline.
That strategy will place C-COR in direct competition with N2 Broadband, a VOD backoffice supplier and system integration specialist based in Atlanta, Ga.
For its part, N2 has announced OpenStream integrations and/or deployments with servers from nCUBE, SeaChange, Concurrent, Broadbus, Kasenna, Arroyo Video Solutions Inc., Entone, MidStream and InfoValue.
SeaChange and Concurrent, meanwhile, have not yet announced integrations with any third-party server makers.
The addition of nCUBE is the latest in a string of acquisitions by C-COR, which is reinventing itself as a supplier of next-generation broadband equipment and software for cable operators and other service providers.
nCUBE marks C-COR's fifth acquisition in this year alone. In 2004, the State College, Pa.-based company has snapped up Alopa Networks, a provisioning and OSS specialist; Stargus Inc, a network management software company; and two IP transport firms: Lantern Communications and Optinel Systems.
"If you look at where the industry is going...all of these [acquisitions] fit the strategy we have for an end-to-end solution for operators building a next-generation network," Wright explained.


text:
Move a PGP Desktop for Mac client to a new PGP Universal Server
|Created: 2009-01-30
|Updated: 2015-01-26
|Article URL http://www.symantec.com/docs/TECH149269
This article details how to bind a PGP Desktop for Mac client to another PGP Universal Server.
To bind a client to a new PGP Universal Server, you must delete the PGP Preferences for the client and then update the PGP Stamp in the configuration string to move the client to the new server.
- Exit PGP Desktop and then quit the PGPengine service by opening Utilities > Activity Monitor.
- Remove the PGP Desktop preferences:
Open the terminal application and run the following command:
rm ~/Library/Preferences/com.pgp.*
- Update the client to the new server:
defaults write com.pgp.pgp configurationString "ovid=hostname.example.com&mail=*&admin=
Note: Another method that works as opposed to step 3 is to use an echo method in a terminal:
echo "ovid=hostname.example.com&mail=*&admin=1" > /Applications/PGP.app/Contents/Resources/policy.txt
Replace the hostname.example.com with the FQDN of your PGP Universal Server
Legacy ID
Article URL http://www.symantec.com/docs/TECH149269
Terms of use for this information are found in Legal Notices


text: I love to travel and learn about different cultures and religions. I am very clean and attentive. I am vegetarian and health and the environment are very important to me. I come from a large loving family. I grew up in Toronto, but I have lived in Hawaii, Asia and Europe for many years! Please feel free to ask me any other questions. Oh, I work in the Nutraceutical industry - health industry.


text:
3/3 CBS2 Tuesday Evening Weather Headlines
Snow is falling over most of us, but soon we will make a switch over to sleet and rain.
2/27 CBS2 Friday Evening & Weekend Weather Headlines
We're in for another cold night to kick off the weekend. Temps will drop into the single digits for most, with even some subzero lows far north and west in places like Monticello.
2/22 CBS2 Sunday Morning Weather Headlines
Good morning everybody! We're seeing some rain showers for much of the area, but temps are a bit too close for comfort to the freezing mark.
2/21 CBS2 Saturday Morning Weather Headlines
Hope you're having a good day so far. Another wickedly cold start for the Tri-State today as single digits and low teens encompass us.
2/17 CBS2 Tuesday Evening Weather Headlines
The snow is long gone and out towards Boston. We were pretty good with the forecasting having the largest totals in south New Jersey and smaller totals in the Hudson Valley.
2/2 CBS2 Monday Evening Weather Headlines
What a mess out there today. Heavy snow for some, heavy rain for others, and worst of all, ice for most of our drivers. Slow commuting tonight, please take your time.
Tri-State Deals With Snowy, Slushy Aftermath Of Winter Storm
Another round of winter weather coated the Tri-State area in snow, slush and ice Saturday.
1/24 CBS2 Saturday Morning Weather Headlines
If you can stay in this morning and relax, that would definitely be the thing to do on this Saturday. Snow moved in overnight and is now in the process of changing over to rain/mix from south to north.
1/23 CBS2 Friday Evening Weather Headlines
After a bright finish to the work week, we're now gearing up for some more winter weather for the Tri-State region, all associated with a fast moving coastal storm.
1/23 CBS2 Thursday Morning Weather Headlines
Clear skies are the rule this morning, not the exception. But clear skies also means very cold temps around the horn. Expect the teens to the north, and as mild as upper 20s near the coast.
1/22 CBS2 Thursday Evening Weather Headlines
Today was quite pleasant for the middle of January! We hit 40 degrees in NYC and even milder around the Tri-State.
1/22 CBS2 Thursday Morning Weather Headlines
Be careful out there this morning if your traveling in Monmouth and Ocean County. The NWS extended their advisory until 8 a.m.
1/17 CBS2 Saturday Morning Weather Headlines
You'll definitely wanna bundle up if you're headed out, because temps took a plunge overnight! We're in the teens in the city and single digits for some of the suburbs. With a persistent northwest wind, it'll feel closer to zero as you start your day!
1/16 CBS2 Friday Evening Weather Headlines
By Giorgio Panetta, CBS2 Chief Meteorologist/Weather Producer Good evening, Skies have been mostly sun filled today. Temps have been above normal too! It felt quite nice this afternoon when I stepped out for a coffee. […]
1/14 CBS2 Wednesday Evening Weather Headlines
Some good news ahead — we get warmer every day this week.


text:
Health Nut is now open until 7:30 PM on weekdays and 7 PM on Saturdays!
Order from anywhere with our new Health Nut mobile app!
Our refreshing Mango Passion Iced Greentini... come try one today!
Our famous Deluxe Salad with Tuna. Fresh, healthy, and delicious!
Health Nut now offers online ordering! Order through our website or try out our convenient new mobile apps!


text:
Get to Work
Explore how to find, get and keep work .
Posts by Author
Maintain good communication skills when working from home
Telecommuting, or working from home, is something more companies are looking at every day. And, for many employees, it can be a great option. But, when you're working from home, you can become isolated from your coworkers and your boss, so communicat… [Read More]
Managing holiday networking challenges
About this time every year, those who dread searching for a new job will undoubtedly share the thoughts of "waiting" until the holidays are over to job search. The notion of conducting a search while family gatherings abound can add an extra layer… [Read More]
Avoid these phrases on your next job interview
Have you ever said the wrong thing during a job interview? An interview can be seen as the grand finale of your hard work and planning. All your job-search activities, networking and researching lead to the interview, the first time you have the chan… [Read More]
The power of gratitude
As Thanksgiving approaches, being mindful of your blessings is a topic of discussion that will take place among friends and families across the nation celebrating the one day designated for giving thanks. Showing gratitude is really being thankful with… [Read More]
What do employers think about job-hoppers?
The chances of changing jobs multiple times in your career is a given in today's marketplace, and according to the Bureau of Labor, the average length of time spent with an employer is under five years. Change is the norm and the stigma of moving fr… [Read More]
Overcome barriers when managing your boss
The idea of managing your boss can seem paradoxical; after all, they are supposed to be managing you. Right? Not really. Managing is a two-way street that means you take ownership of providing your boss with the necessary information while understandin… [Read More]
What your dreams about work could be telling you
Last week, the blog's subject was about facing a nightmarish job and ways to turn it around. This week, your dreams about work could be sending you clues of underlying stress and what this might mean to you. Dreams often reflect your daily life and a… [Read More]
Don't be so terrified of making mistakes
What's your biggest work-related fear? Many people would be quick to say that it's making a mistake at work. The key to keeping your career moving forward is not avoiding mistakes, it's looking at mistakes from a healthy perspective. Most employe… [Read More]
Wake up from a career-related bad dream
Waking up from a nightmare is not a pleasant experience, yet going to work with one every day is an entirely different matter. Most people accept a job with a hopeful attitude of growth and enthusiasm; however, there may be occasions during your care… [Read More]
Common mistakes older job seekers make
When it comes to job searching, age can present challenges, despite the fact that job seekers age 55-plus have more opportunities than ever before. The biggest hurdle, however, is one that occurs within yourself, and that is self-defeat. Sometimes th… [Read More]
Show More


text:
Since the dawn of civilization people were searching for clues to longevity and trying to extend human lifespan. But only in the past two decades with the advances in genetic sequencing, epigenetic analysis, and increased government investments the area experienced rapid expansion in the knowledge base, allowing scientists to develop comprehensive models and theories of aging. And while there is still much disagreement among scientists, the evolutionary theories are dominating the field. These theories predicted existence of certain genes that provide selective advantage early in life with adverse effects on lifespan later in life or longevity insurance genes. Indeed, the study of human and animal genetics is gradually identifying new genes that increase lifespan when overexpressed or mutatedgerontogenes. Furthermore, genetic and epigenetic mechanisms are being identified that have positive effects on longevity.
"The study of the effects of mutations and epimutations on life expectancy and the aging rate expands the range of potential pharmacological and genoteraputic targets, as well as biomarkers of treatment of aging-dependent pathologies," said professor Alexey Moskalev, PhD, DSc, head of the laboratories for aging research at the Institute of Biology of the Russian Academy of Sciences and at the Moscow Institute of Physics and Technology.
The international group of scientists performed a comprehensive analysis of the genetic and epigenetic mechanisms and demonstrated that the majority of the genes, as well as genetic and epigenetic mechanisms that are involved in regulation of longevity, are highly interconnected and related to stress response. Also, for the first time, the group performed a comprehensive analysis of government research grants related to the genes involved in aging. One of the tools that may help understand the direction of scientific research that is still unpublished are research grant abstracts. To better understand
|Contact: Andrew Thompson
Landes Bioscience


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Wexford Youths Women claim league title
Wexford Youths Women were crowned FAI Continental Tyres Women's National League champions for the first time after recording a 2-1 victory over Raheny United at Morton Stadium on Saturday.
Wexford Youths Women were crowned FAI Continental Tyres Women's National League champions for the first time after recording a 2-1 victory over Raheny United at Morton Stadium on Saturday.
A last-gasp goal from Brian Hurley gave Cork a 2-07 to 0-12 Allianz Football League Division 1A win over Mayo at Páirc Ui Rinn in a game in which the Rebels were far from their best.
Leinster have confirmed that Rhys Ruddock will miss next Saturday's Champions Cup quarter-final against Bath at Aviva Stadium.
Donegal coasted to an emphatic 1-13 to 0-06 victory which pushed rivals Tyrone closer to relegation from Division One of the Allianz Football League.
Fermanagh confirmed their place in the Allianz NFL Division 3 Final, while there were also wins for Tipperary and Limerick this afternoon.
Joseph O'Brien plans to continue riding under both codes after finishing down the field on his first ride over jumps at Limerick.
Galway turned a seven-point half-time deficit into a 1-14 to 1-10 victory over Roscommon at a windswept Hyde Park to renew their chances of remaining in Division 2.
Australia have won the World Cup with a seven-wicket victory over New Zealand in Melbourne.
Relive the action from the Allianz Hurling League Division 1 quarter-finals and relegation play-off.
Relive the action from the Allianz Football League with games in all four divisions, including the meeting of Cork and Mayo.
Tipperary extended their run of league wins to five with a 1-16 to 0-13 victory over Offaly at O'Connor Park in Tullamore, but Eamonn O'Shea will be counting the cost of that triumph with injury and suspension issues.
Ireland's Aileen Reid finished in 15th place in the ITU Triathlon World Series, Auckland, New Zealand, today.
Team Sky's Richie Porte clinched the Volta a Catalunya title on Sunday to add to his success at Paris-Nice earlier this year.
Nick Williams, the Ulster No 8, has been cited by an independent citing commissioner for allegedly striking Cardiff's Rhys Patchell in their Pro12 match at Kingspan Stadium last Friday.
Ferrari are back as Sebastian Vettel ended the famous marque's 34-race drought without a victory by taking a well-deserved chequered flag in Malaysia.
Robbie Keane is certain he still has international goals to score as he approaches the twilight of his glittering career.
Daryl Jacob will partner Pineau De Re when the horse goes in search of back-to-back victories in the Crabbie's Grand National on Saturday week.
Ireland cricketer John Mooney has revealed how difficult the recent World Cup campaign was for him as he continues to battle mental health issues.
Jimmy Walker will take a four-shot lead into the final round of the Valero Texas Open after carding a three-under-par 69 at TPC San Antonio on Saturday.
Four Dublin points in a row in the concluding stages of a tense Croke Park contest were enough to finally shake off stubborn Derry on a 0-08 to 0-04 scoreline.