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Strange Bedfellows -- Politics News
News about Seattle and King County government as well as national politics.
Posts filtered on Category
Redmond council fears for bridge, opposes Eyman
The Redmond City Council voted late Tuesday to oppose Tim Eyman's Initiative 1125, fearing it would raise costs and jeopardize the S.R. 520 bridge project. "I-1125 is not in the best interests of Redmond due to the increased costs that would result from replacement of the S.R. 520 bridge and the threat to mobility on […] [Read More]
Downtown Seattle Assn: No on 1125
The Downtown Seattle Association on Monday became the latest major business group to oppose Tim Eyman's Initiative 1125, which would restrict use of tolls to pay for new transportation projects. "It threatens vital transportation projects and our continued economic growth," said DSA President Kate Joncas. A bevy of business groups around the state, including sometime […] [Read More]
Business group backs $60 car tab fee
The Downtown Seattle Association, representing major business interests, is backing Prop. 1, the controversial $60 car tab fee on Seattle's November ballot. Supporters of the car tab fee now have backing from major business and labor — The M.L. King County Labor Council — but have been unable to secure endorsements from most major Democratic […] [Read More]
Renton City Council – no on Eyman initiative
The City Council in Renton, a city at the fulcrum of pending state transportation projects – notably expansion of Interstate 405 – has unanimously voted to oppose Tim Eyman's Initiative 1125. The council voted Monday after holding a public hearing on I-1125. It would limit application of tolls to pay for new bridge and highway […] [Read More]
Big union backs $60 car tabs
The Aerospace Machinists, representing 45,000 active, retired and laid-off Boeing workers, has endorsed the $60 car tab measure on Seattle's November ballot. Prop. 1, put on the ballot by the Seattle City Council, would impose an annual $60 fee for 10 years on all cars owned in the Emerald City, from clunkers to fancy SUV's. […] [Read More]
Business group: No on Eyman's I-1125
A key player in state politics has come out against Initiative 1125, the Tim Eyman-sponsored, Kemper Freeman-bankrolled ballot measure that would severely limit tolls to pay for new bridges and highways. The Association of Washington Business took a no-on-I-1125 stand during its annual policy summit at the Suncadia resort near Cle Elum in the Cascades. […] [Read More]
McGinn wants $1.5 million from rubble yard sale for transit planning
Seattle Mayor Mike McGinn wants to spend $1.5 million from the sale of an SDOT maintenance yard to begin planning for a new streetcar line, the mayor announced Thursday. The "Rubble Yard" was sold for $19.8 million to the state Department of Washington, which wanted it for construction of the new State Route 99 tunnel. […] [Read More]
EPA gives green light to Shell work in Arctic
The U.S. Environmental Protection Agency on Monday gave final air quality permits to Shell for its controversial oil and gas exploration in waters of the Alaskan Arctic. [Read More]
$60 car tab fee – opposition from the left
Boasting a surprising list of longtime Seattle liberal activists, the group Citizens Against Raising Car Tabs will on Tuesday launch its campaign against the city's proposed $60 car tab fee. The car tab fee, Prop. 1 on the November ballot, is generating more opposition than any property tax or fee measure put before Seattle's usually […] [Read More]
State GOP embraces Eyman initiative
The Washington State Republican Party, splitting from many of its business backers, is endorsing Tim Eyman's Initiative 1125, which would severely restrict use of tolls to pay for bridge and highway projects. "It is important that we hold Olympia accountable and 1125 does just that," said State GOP chairman Kirby Wilbur. The initiative would require […] [Read More]
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Acute Vs Chronic Hepatitis C
Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
Acute HIV Infection... What Is Acute HIV Infection? Testing for Acute HIV Infection Risk of Immune Damage Risk of Infecting Others Treating Acute HIV Infection Pros and Cons of Treating Acute HIV Infection The Bottom Line What Is Acute HIV Infection?
Ask the Experts
is this acute or chronic hep-cI am a health care worker.Back in 1992 I had some mild increase in LFT ALT 60 hepatitis-c antibody was negative they came down to normal this happend again in 1995 again hep-c antibody was negative at that time also,and in May 2005 hep-c negative...
Response from Barbara McGovern, M.D.
Tufts University School of Medicine...For health care workers, needlestick injuries with exposure to blood can lead to acute hepatitis C. I believe that is what happened to you. 1. Your liver function tests in the past were only modestly abnormal and Read more »
Can you clarify?Dr. McGovern, Hello I wanted to know if you could clarify something about Hepatis C? I just read a post from someone who posted on June 22nd. You said one wouldn't have to worry about testing for HIV out to a year unless they got ACUTE...
Response from Barbara McGovern, M.D.
Tufts University School of Medicine...than 12 months ago. When testing a patient with acute hepatitis C, the liver function tests become extremely high whereas in chronic hepatitis C the liver function tests are usually just mildly or moderately abnormal. Some patients do feel sick;... Read more »
Acute/ChronicHi Doctor, The past months I have been ill after stupidly having unprotected casual sex. HIV has been ruled out with a number of tests out so seven months. The doctors are now looking at a possible HCV infection, I get tested this week, this will be...
Response from Barbara McGovern, M.D.
Tufts University School of MedicineHepatitis C is uncommonly transmitted through sex so I would doubt that one episode of unprotected intercourse led to hepatitis C infection. I would also check for hepatitis B which is more likely to be tranmitted through sex than hepatitis C. If... Read more »
what to do????????My husband has been told that he may infact have hepititas c..We have been married 3 yrs now. I have 2 small children from my prior marrage that live in the same house with us. My concern is for me and my children not to be infected with this virus....
Response from Robert J. Frascino, M.D.
The Robert James Frascino AIDS Foundation...virus from their bodies, usually within six months. However, the majority of people (80%) who are infected with HCV develop chronic hepatitis C, and the infection will likely stay with them for the rest of their lives or until treatment clears... Read more »
FAQs for the Public: Hepatitis C...hepatitis C? What is hepatitis C? Statistics How common is acute hepatitis C in the United States? How common is chronic hepatitis C in the United States? How likely is it that acute hepatitis C will become chronic? ... Read more »
Availability of Draft Guidance Re: Development of Antivirals for Chronic Hepatitis C, Including Coinfection With HIV... The Food and Drug Administration (FDA) is announcing the availability of a draft guidance for industry entitled "Chronic Hepatitis C Virus Infection: Developing Direct-Acting Antiviral Agents for Treatment," which includes co-infection with HIV.... Read more »
Hepatitis: Overview...G viruses, or HAV, HBV, and so on. Over 90% of cases of hepatitis are caused by hepatitis A, B, or C. Viral hepatitis can be acute or chronic. Acute means the first few weeks to months after you get hepatitis. You may feel sick for a couple of... Read more »
Hepatitis C and HIVWhat Is Hepatitis C? How Is It Diagnosed? How Is Hep C Treated? Can Hep C Be Prevented? Hep C and HIV Together The Bottom Line What Is Hepatitis C? The hepatitis C virus (HCV) can cause liver damage. HCV is transmitted by... Read more »
Connect With Others
acute infection
Posted by bennetcj, 1 Reply...to do iv drugs, and although he claims he never shared needles, there is a good chance that is a lie. I have read up on what acute symptoms are like, and the only ones i have of those are diarrhea (lasting about 20 days) and swollen glands.... Read more »
HIV acute viral syndrome on the 18th week
Posted by marinero, 1 Reply...first week of may 2009 which is the 18th week since possible exposure, i got 4 day fever, rashes,diarrhea and muscle pain,does acute viral syndrome can occur on the 18th week? could this be hiv symptoms? Read more »
Antimicrobial & Acute Hiv
Posted by sickofit, 1 Reply...A person is exhibiting classic signs of acute hiv ie: sore throat, swollen lymph nodes, muscle pains, general fatigue. They take the antimicrobial zithromax and have all Read more »
Meaning of Acute
Posted by Anonymous, 1 Reply...I thought the meaning of the word acute meant temporary and not long lasting, as opposed to chronic, which means persisting. I hear a lot of people think they have "acute" Read more »
Resource Centers
Guides for People With HIV


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drinking: mocha java porter, belgian pumpkin ale, Gary's oatmeal stout clone, AHS nut brown, catamount porter clone, double nut brown, rye pale ale, my oatmeal stout
conditioning: nut brown
next: saison, wit, american wheat, hefe, kolsch, blonde
gone: too damn many
Saranac Black Forest, Heineken (from the back of the supermarket fridge so it's not skunky), Dogfish Head IPA, Old Milwaukee. Yes, Old Milwaukee. It got me through college. Excellent for drinking games, power hours, bottle throttles, and charging $5 a cup when the whole keg costs $55.
Kegged: Smokier Smoked Porter
Relentless pursuit of better beer
Yeungling's Chesterfield Ale.
How about another vote for Hop Rod Rye?
Hey baby....
I've never had it, but for some strange reason I need to cast my vote for Hop Rod Rye. I love that stuff. I could drink C and D cups full of it.
Once the wind has been broken, it cannot be fixed.
I'd drink Big 3 Fizzy Yellow Beer like every other non-brewing A. hole in this fair land of ours. If I couldn't make it, I might as well not taste it. The end result would still be the same.
More like a sock monkey, really...


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Friday, March 27, 2015
A travel center designed to cater to foreign tourists has been established in historic Daxi Township (大溪鎮) in northern Taiwan's Taoyuan City (桃園市) as part of the country's efforts to promote travel to local townships, officials said Thursday.
The Pingtung County Government has teamed up with Line to hold the first Color Rice Field Art Festival on March 28, where Line Friends will be showcased on a field.
Thursday, March 26, 2015
The sinking of a research ship off the coast of Taiwan's Penghu Island late last year was due to human error, the Maritime and Port Bureau (航港局) said Wednesday.
A suspect surnamed Chang has recently been questioned by prosecutors over her alleged involvement in an apartment rental scam, the Criminal Investigation Bureau (CIB) said.
Wednesday, March 25, 2015
Taipei Mayor Ko Wen-je (柯文哲) yesterday announced the establishment of the Taipei City Joint Center for Project Contract Outing and Purchasing, a department that will handle all city government construction dealings openly, so as to eradicate corrupt practices.
Tuesday, March 24, 2015
Taipei Mayor Ko Wen-je (柯文哲) yesterday responded to a same-sex couple who asked the mayor to act as a witness during their marriage ceremony should Taipei's City Government authorize their application., 3 Comments
Taichung Mayor Lin Chia-lung (林佳龍) announced Monday that the city's existing bus rapid transit (BRT) system will be replaced by "optimized dedicated bus lanes" that will start operation July 8.
A luxury hotel was fined NT$300,000 (US$9,563) by Taipei City's government on Sunday for an incident when a pedestrian was injured by tiles falling from the facade of its building.
The Ministry of Transportation and Communications (MOTC) said Monday that it remains positive about the future of Taichung's controversial bus rapid transit (BRT) system following a decision by the local government earlier in the day to convert the BRT lanes into dedicated bus lanes that can also be used by normal city buses.
A major wine importer based in New Taipei was busted for selling counterfeit French red wine that netted the company a profit estimated at NT$100 million (US$3.19 million) over the past five years, the Investigation Bureau (調查局) said Monday., 3 Comments


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Mach 1 Tribute, beautiful Bright red paint, black Mach 1 striping, black vinyl interior, Professionally Built 302 ci engine, Holley 4 bbl, Edelbrock Performer... More
1973 MUSTANG MACH ONE. . . . . MEDIUM BRIGHT YELLOW PAINT ON A STRAIGHT BODY. . . . RAM AIR STYLE HOOD IN... More
1973 Cadillac Sedan DeVille - 472 V8, automatic, power steering, power brakes, air conditioning, dual power seats, power windows, power locks, AM/FM stereo with... More
1973 Honda CL350 twin ''Scrambler'', good original condition, Blue with white stripes, new tires and tubes, great sounding Honda 350 twin engine, starts easily... More
Chassis# 9113102418 Engine# 6134458 Gearbox# 7338193 Paint Code: 335 (Gemini Blue) A 1973 Porsche 911T, 2.4 liter CIS Coupe. All the numbers are correct, but I cannot verify... More
1973 Lotus Europa Type 74 Twin Cam John Player Special finished in classic JPS Black with Gold trim. Only 3,130 Lotus Europa Specials were... More
1973 Mercedes Benz 450SLClean title86000 original milesV8Auto transmission3rd owner Owned since 2003 Averaged 1000 miles per yearGaraged and well maintainedClean inside and outRuns strongVehicle... More
Stk. 1064 1973 Chevrolet Corvette The red exterior on this Vette is accented with a light tan top that matches the interior. It offers a... More
This 1973 Jaguar Series III V12 Roadster is a great restored example that boasts a number of performance and comfort upgrades. It features a... More
1973 Chevrolet Corvette StingrayMatching Numbers, 454, CID 275 HP,3-Speed Automatic Transmission,White Exterior Paint with Saddle Color Interior,Rally Wheels, A/c Power Brakes,Power Steering, Power Windows,T-TopsAuto... More
1973 Mercedes-Benz SLC450Clean 1973 Mercedes-Benz SLC450 model in mint conditionBlue metallic exterior with a matching Blue leather interiorRuns great as wellThe Body is in... More
1973 Jeep CJ-51973 Jeep CJ-5 model currently in a restoration conditionGrey metallic exterior with a matching Grey cloth interiorLess than 1000 miles on the... More
1973 Porsche 911E Sunroof Coupe, always garaged, one family owned since new. Excellent Silver/Black factory color combination, 100% solid factory floors with original factory... More
1973 Jaguar XKE Roadster '73 Jaguar XKE Roadster with matching numbers in heather with burgundy interior, a very rare color combination. Equipped with a manual... More
MG B Roadster 1973 in very good condition In very good condition, very well maintained MGB Roadster from 1973 with original, revised, 1800cc 4 cylinder... More
This stunning 1973 1/2 Porsche 911T for sale is a Bay Area car from day one and numbers matching. The CoA from Porsche is... More
Up for sale in our Tampa Showroom is this gorgeous 1973 Datsun 240Z. Growing in both rarity and popularity these cars are climbing the... More
1973 Ford Mustang CabrioThis car just came in.More information and additional pictures will follow as soon as possible.For more information you should contact us.... More
1973 Ford Mustang ConvertibleThe Mustang is the American Oldtimer that everybody knows.This beautiful silver Convertible is in a very good condition and drives very... More
1973 Chevrolet Corvette C3 TargaA nice Corvette in a good condition.The American paintjob is in a good state and the red color matches perfect... More
1973 Ford Mustang ConvertibleThis Mustang Convertible is in a good condition. The electrical top is in a very good condition and works perfectly. The... More
1973 Cadillac Deville Hearse-Miller, LeichenwagenThis Cadillac Hearse-Miller is the American hearse. Cadillac has a lot of space inside and is longer than many limousine.... More
1973 Ford Mustang Mach IThis Mustang Mach I is a true sports car from 1973. With its sporty paintwork, the sporty rims, the NACA... More
1973 Cadillac Eldorado 2dr CoupeA very nice Eldorado from 1973. The paint is in good condition and the chrome is well maintained. The 8.2... More
1973 Chevrolet Camaro Z28 OptikThis beautiful and sporty Camaro looks just top off with his Z28 look. The paint looks perfect and chrome also... More
1973 Chevrolet Corvette C3 TargaThe Corvette is one of the most beloved classic American sports cars. This 1973 Corvette is in very good condition.... More
1973 Ford Mustang Mach 1 Fastback1973 Mach1 Mustang. Great classic American car in excellent shape! Features - TN carOne respray 15 years agoEvery thing... More
Check out this Sharp 1973 Challenger! This car has a great sounding and running 318 motor with only 73,000 original miles.. and an automatic 727... More
This is a 1973 Ford Bronco in excellent condition.This is a very nicely restored Bronco, 302 V8, 3 speed transmission, comes with Flaming River... More
Shoving a big engine in a small car isn't a new formula, but the Triumph TR6 is one of the most affordable ways to... More


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Lottie Pickford
Jun. 9, 1895
Ontario, Canada
Dec. 9, 1936
Los Angeles County
California, USA
Actress. While she never enjoyed the popularity of her older sister, the legendary actress
Mary Pickford
, or her younger brother
Jack Pickford
, she nevertheless had a modest amount of fame in her own right. Like her siblings, she also got her start in acting by playing juvenile roles in stage plays upon the urging of their mother Charlotte. However, she primarily served as Mary's understudy and dresser instead of getting prominent roles herself. They moved from stage acting to screen acting in 1909 when they were signed by Biograph Studios. For the next few years she appeared in numerous shorts, although many times she was cast in uncredited or bit roles. Among these shorts were 'The Light That Came' (1909), 'To Save Her Soul' (1909), 'A Summer Idyll' (1910), 'Two Little Waifs' (1910), 'A Wreath of Orange Blossoms' (1911), and 'Three Sisters' (1911). In 1911, she left Biograph and began working at various other studios, such as Inceville, Vitagraph, and Photo Drama Motion Picture Company. Although she appeared in a number of shorts and, later, features with her older sister, with her younger brother, and sometimes worked in movies with both of them, the only full-length feature in which all three Pickford siblings appeared together was 'Fanchon the Cricket' (1915), in which they played the leading roles. Following this, she began to enjoy more important leading roles in movies, such as 'The Diamond from the Sky' (a 1915 serial), 'The Reward of Patience' (1916), 'The Man from Funeral Range' (1918), and 'They Shall Pay' (1921). Originally her sister Mary had been offered the leading role in 'The Diamond from the Sky,' but she turned down the opportunity and their mother Charlotte suggested Lottie to the serial's producers. When the original director abandoned the project after finding out that Lottie was pregnant (by her husband George Rupp),
William Desmond Taylor
obligingly took over. His quality of work and his kind treatment of Lottie influenced Mary to eventually hire him as her own director. Lottie's child was officially christened Mary Pickford Rupp, although she later had her daughter's name changed to Gwynne. When she divorced Rupp in 1920, her mother Charlotte and her sister Mary took over Gwynne's upbringing. Lottie later remarried to the actor Allan Forrest, and appeared in her last two films, 'Dorothy Vernon of Haddon Hall' (1924) and 'Don Q, Son of Zorro' (1925), under the name Lottie Pickford Forrest. However, this marriage too didn't last, and in 1928 they got divorced. Her final marriage was to Russel O. Gillard, an undertaker. This marriage similarly ended in divorce in 1933. Like her younger brother Jack, whom she idolized, Lottie had also developed problems with drinking and with throwing notoriously wild parties. This lifestyle would eventually lead to the premature end of her acting career and her death at the age of only forty-one.
(bio by:
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John Charles Smith (1866 - 1898)
Smith (1873 - 1928)
Gwynne Pickford
Ornstein (1916 - 1984)
Mary Pickford (1892 - 1979)
Lottie Pickford (1895 - 1936)
Jack Pickford (1896 - 1933)
Calculated relationship
Cause of death: Heart attack
Forest Lawn Memorial Park (Glendale)
Los Angeles County
California, USA
Plot: Garden of Memory
Maintained by: Find A Grave
Record added: Dec 19, 1999
Find A Grave Memorial# 7878
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Chet Walker
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Texas Politics
All Texas politics all the time from the San Antonio Express-News and Houston Chronicle
Terri Hodge is back, campaigning for "felons, just like me"
DALLAS — Not one to let a felony conviction for tax fraud keep her down, former State Rep. Terri Hodge is running to become the vice chair of the Texas Democratic Party. [Read More]
Attending this party will cost you at least $1,000
DALLAS — As Democrats gather for their state convention, big-deal Democratic supporter Lisa Blue Baron is hosting a fundraiser for the Lone Star Project, which is directed by Matt Angle, an adviser to Sen. Wendy Davis who has long been active in pro-… [Read More]
Abbott drops $10 million for fall airtime in governor's race
AUSTIN — Attorney General Greg Abbott's gubernatorial campaign is spending $10 million to reserve airtime in the final full month of the election, the San Antonio Express-News has learned, in what amounts to an early precursor of the extravagant ad… [Read More]
Wendy Davis promises victory
AUSTIN – Democratic Sen. Wendy Davis, acknowledging some have already written off her candidacy for governor, promised victory to supporters marking Wednesday's anniversary of her nationally noted filibuster against tighter abortion restrictions. .. [Read More]
Republicans, Democrats fight over filibuster on anniversary
AUSTIN – Sen. Wendy Davis and fellow Democrats celebrated the anniversary of her filibuster against tighter abortion laws Wednesday as a fight for women's rights. Republicans suggested that the only positive aspect of the anniversary is that her ef… [Read More]
Perry's 'Trail of Tears' comment draws criticism
Perhaps it should come as no surprise that, at a time when the Washington Redskins are mired in controversy for having an insensitive name, that Gov. Rick Perry's comparison of the voluntary flood of undocumented migrants into Texas to the infamous "Trail of Tears" is drawing criticism. The Trail of Tears is the name of […] [Read More]
Feds say new Texas land belongs in public domain
AUSTIN – Land once considered part of Oklahoma that now is in Texas due to shifts along the Red River belongs to the federal government, the U.S. Bureau of Land Management has told state officials. In a letter sent June 20 to Texas Attorney General Greg Abbott, BLM Director Neil Kornze noted that the 2000 […] [Read More]
Investigation to launch into UT-Austin admissions practices
AUSTIN – The University of Texas System is slated to launch a full-scale investigation into admissions practices at its flagship campus in Austin, just weeks after a preliminary look into possible legislative influence over the process failed to unearth anything concerning for system officials. "There's been some other information that's come to light, some questions […] [Read More]


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M30 Expression Demonstrates Apoptotic Cells, Correlates With in Situ End-Labeling, and Is Associated With Ki-67 Expression in Large Intestinal Neoplasms.
The techniques most widely used to demonstrate apoptotic cells in paraffin sections are terminal deoxyribonucleotidyl transferase-mediated deoxyuridine triphosphate-biotin nick end-labeling (TUNEL) and in situ end-labeling (ISEL).[34] Both methods detect the DNA strand breaks characteristic of apoptosis by adding nucleotides, including deoxyuridine triphosphate labeled with biotin, to the ends of the broken DNA.[5-8] The only essential difference between the two is that TUNEL uses the enzyme terminal deoxyribonucleotidyl transferase,[6] whereas ISEL uses DNA polymerase I or its Klenow fragment.[7-9] Therefore, TUNEL can label DNA fragments with blunt ends or with ends that are either 3' recessed or 5' recessed, whereas ISEL only detects 3' recessed ends.[10] Although these techniques (particularly TUNEL) have been used extensively in the study of neoplastic and nonneoplastic disease, they are not without their disadvantages. They both mark necrotic and autolytic cells in addition to apoptotic cells.[2,3,11] They require pretreatment steps that need careful optimization, and the results depend on how these steps are performed.[5,12,13] Some false-positive reactions appear to be produced by endogenous endonucleases released during proteinase digestion; endonuclease inhibition can abolish this effect.[14] Studies into the effects of fixation and prefixation times have yielded variable results.[15-17] Prolonged fixation times can reduce the number of detectable apoptotic cells,[15] while delayed fixation can increase their number[16]; on the other hand, prolonged archival storage of paraffin blocks appears to have a negligible effect.[17] There is good evidence that the physical act of cutting the tissue to produce sections creates TUNEL reactivity.[18] Furthermore, interassay variability in TUNEL has been demonstrated.[19] Some authors believe that morphology is superior to TUNEL or ISEL for the detection of apoptosis.[1,19]
Another means of identifying apoptotic cells has been described recently.[20] It is a monoclonal antibody called M30, which recognizes a neoepitope of cytokeratin 18 (CK18) in paraffin-embedded tissue. This neoepitope is produced by caspase cleavage of CK18 during apoptosis and is not present in nonapoptotic cells.[20] An advantage over TUNEL and ISEL is the lack of M30 expression in necrotic cells. Since CK18 has wide distribution, being present in virtually all simple, ductal, and pseudostratified epithelia, the demonstration of M30 immunoreactivity could be immensely useful in the investigation of apoptosis in tissue sections.
This study used adenomas and adenocarcinomas of the large intestine with 2 aims: to perform a direct comparison between M30 and ISEL to determine the relationship between them, and to compare the results with Ki-67 expression.
One hundred cases of sporadic adenoma and adenocarcinoma of the large intestine from 100 different patients were selected from the archives of the Royal Air Force Institute of Pathology (Halton, Buckinghamshire, United Kingdom), the Royal Hospital Haslar (Gosport, Hampshire, United Kingdom), and St Mark's Hospital (Harrow, Middlesex, United Kingdom). Five-micrometer-thick sections were cut from paraffin blocks of the formalin-fixed tissue.
In situ end-labeling was performed according to a protocol based on the techniques of Ansari et al[7] and Wijsman et al.[9,12] After being dewaxed in xylene and hydrated in ethanol and water, endogenous peroxidase activity was abolished by placing the slides in a 1% solution of hydrogen peroxide in distilled water for 10 minutes. The slides were rinsed and incubated at room temperature in a 0.5% solution of pepsin. This solution was prepared by dissolving lyophilized pepsin 1:60 000 (2500-3500 units/mg protein) (Sigma, Poole, Dorset, United Kingdom) in 0.1 mol/L hydrochloric acid. Following a thorough rinsing, the slides were allowed to dry (about 20 minutes). The solution for the nucleotide-polymerase reaction was 50 mmol/L Tris-HCl, pH 7.4 (Sigma); 5 mmol/L magnesium chloride; 10 mmol/L 2-mercaptoethanol; 0.005% bovine serum albumin; 0.02 mmol/L deoxyadenosine triphosphate, deoxycytosine triphosphate, and deoxyguanosine triphosphate (Sigma); 0.004 mmol/L bio-21-dUTP (Clontech, Palo Alto, Calif); and 30 units/mL of DNA polymerase I (Sigma) in distilled water. The sections were covered with this solution and incubated for 90 minutes at 37 [degrees] C. The biotin-labeled nucleotide was detected with streptavidin-biotin (Dakopatts, Glostrup, Denmark) and 3,3'-diaminobenzidine-hydrogen peroxide. The sections were then counterstained with hematoxylin, dehydrated, and mounted. Each batch of slides included a positive control (a colonic adenocarcinoma) and a negative control (the same carcinoma treated in the same way, except that the polymerase was omitted from the nucleotide solution). The sections were examined microscopically at high power. At least 2000 cells per case were counted; positive cells were defined as cells with nuclei, whole or fragmented, showing morphology consistent with apoptosis.[12] Zones of necrosis and apoptotic fragments in glandular lumina were not counted. The number of positive cells was expressed as a percentage of the total number of epithelial cells counted.
M30 immunostaining was performed as follows. Sections were dewaxed in xylene and hydrated in ethanol. Antigen retrieval was performed by placing the slides in plastic Coplin jars containing target retrieval solution (Dakopatts) and heating in a microwave oven (Energy Beam Sciences model H2800, The Laboratory Microwave Company, Agawam, Mass). The temperature of the retrieval solution was raised to 98 [degrees] C, and then this temperature was maintained for 15 minutes. The sections were allowed to cool in this solution for about 15 minutes and then washed. Hydrogen peroxide solution from the EnVision kit (Dakopatts) was applied for 7 minutes, then the slides were washed and incubated with serum-free protein block (Dakopatts). The primary antibody solution was a 1:150 dilution of M30 (Roche Diagnostics, Lewes, Sussex, United Kingdom) in Tris-buffered saline (Dakopatts) with 0.05% Tween 20; it was applied for 1 hour at room temperature. After rinsing, labeled EnVision polymer (Dakopatts) was added for 30 minutes, and the presence of bound antibody was demonstrated with the substrate-chromogen solution (hydrogen peroxide and 3,3'-diaminobenzidine) from the EnVision kit. The slides were counterstained with hematoxylin, dehydrated, and mounted. Each batch of slides included a positive control (a colonic adenocarcinoma). The negative control was the same carcinoma treated identically, except that the primary antibody was omitted. In an additional experiment, the primary antibody was replaced with isotypic mouse immunoglobulin IgG2b (Sigma) at the same concentration. The sections were examined at high power, with at least 1000 cells being counted in each case. Cells exhibiting immunoreactivity for M30 were expressed as a percentage of the total number of epithelial cells counted.
Immunohistochemistry for Ki-67 followed standard procedures. Tissue sections were dewaxed and hydrated as described for M30. Antigen retrieval was performed by placing the slides in a citrate buffer (0.01 mol/L citric acid with 80 g of sodium hydroxide per liter, adjusted to pH 6.0) and heating in a microwave for 15 minutes at 95 [degrees] C. After cooling and washing, a 3% solution of hydrogen peroxide in distilled water was applied, followed by washing and incubation with the blocking reagent from the LSAB kit (Dakopatts) for 5 minutes. The primary antibody solution was a 1:25 dilution of Ki-67 monoclonal antibody (Dakopatts) in phosphate-buffered saline; slides were incubated in antibody solution for 3 hours at room temperature. The slides were rinsed, incubated with the link antibody, and then incubated with the streptavidin peroxidase solution from the LSAB kit. The presence of bound antibody was demonstrated with 3,3'-diaminobenzidine-hydrogen peroxide solution. The slides were counterstained with hematoxylin, dehydrated, and mounted. Each batch of slides included a positive control and a negative control, as for M30 and ISEL. At least 1000 cells were counted in each case. Cells with nuclei showing immunoreactivity for Ki-67 were expressed as a percentage of the total number of epithelial cells counted.
The data were analyzed using Stat-100 (Biosoft, Cambridge, United Kingdom). P values are quoted to 2 decimal places; P [is less than or equal to] .05 was considered significant.
Nineteen of the 100 cases (12 adenomas, 7 carcinomas) failed to give satisfactory results with ISEL, either because of nonspecific reactions in normal nuclei or lack of reaction despite the presence of apoptotic cells morphologically. These cases were excluded from the study, leaving 81 cases for analysis. The mean age of the 81 patients was 62 years. Thirty-one cases involved adenomas; the mean age of patients in this group was 60 years, and the male-female ratio was 18:13. Sixteen adenomas were from the right side of the large intestine, and 15 were from the left. Mild dysplasia was present in 17 adenomas, moderate dysplasia was noted in 11, and severe dysplasia was identified in 3. Fifty cases represented carcinomas; the mean age of patients with carcinomas was 63 years, and the male-female ratio was 34:16. Twenty-three carcinomas were from the right side, and 27 were from the left. Five cases were Dukes stage A, 19 were Dukes stage B, and 21 were Dukes stage C. In 5 patients the Dukes stage was unknown. Histologically, all the carcinomas were adenocarcinomas.
The results of the ISEL and M30 experiments are given in the Table and a scatterplot of the counts is shown in Figure 1. Simple linear regression showed a strong positive correlation between ISEL and M30 counts (t = 7.44, P = .00). The residuals around the regression line were normally distributed. The distributions of the counts were skewed markedly to the right, and this skewness persisted even after logarithmic transformation. Therefore, nonparametric tests of correlation were used. The Spearman rank correlation coefficient (p) was 0.80 (2-sided probability P = .00). The Kendall correlation coefficient ([Tau]), adjusted for ties and continuity corrected, was 0.60 (P = .00).
[Figure 1 ILLUSTRATION OMITTED]
Counts of In Situ End Labeling (ISEL) and M30 All Cases Adenomas ISEL M30 ISEL M30 n 81 81 31 31 Mean 0.98 1.30 0.64 0.98 95% CI for mean 0.47-1.49 0.36-2.24 0.34-0.94 0.06-1.91 Carcinomas ISEL M30 n 50 50 Mean 1.19 1.50 95% CI for mean 0.28-2.01 0.06-2.90
Immunoexpression of M30 was generally easier to interpret than ISEL, since cells giving ambiguous signals were rare with M30, but were common with ISEL. The background tended to be "clean" with M30 (Figure 2), although some nonspecific reactivity in mucin caused slight problems in mucinous adenocarcinomas. The range of appearances was similar to that described by Leers et al.[20] Cells with condensed chromatin and cell fragments with pyknotic nuclear material showed granular or diffuse cytoplasmic staining. Some apoptotic bodies apparently at an advanced stage of degradation were negative. Granular reactivity was seen in the cytoplasm of some cells with normal nuclei; these cells were assumed to be at an early stage of apoptosis and were counted as positive.
[Figure 2 ILLUSTRATION OMITTED]
The negative control slides showed no cytoplasmic staining, but a weak nonspecific nuclear signal was observed in 1% to 2% of cells. This signal did not prove troublesome, because only cytoplasmic reactivity is significant in this context. The slides treated with mouse IgG2b showed identical results to the negative control slides.
Despite the significant correlation between M30 expression and ISEL, inspection of Figure 1 shows a wide scatter around the regression line. There is a particularly prominent outlier; it was a signet ring adenocarcinoma from a 73-year-old woman.
Four cases did not have satisfactory Ki-67 immunoreactivity (failure of internal positive controls to react) and were excluded. The mean Ki-67 counts of the remaining 77 cases were 26.8 for adenomas, 25.0 for carcinomas, and 25.7 for all cases combined. Since the set of Ki-67 results had a different number of items than the ISEL and M30 results, the Mann-Whiney U test was used to assess the correlation between Ki-67 counts and the apoptotic indices. There was a strong positive correlation in each case (P = .01 for Ki-67 vs ISEL and for Ki-67 vs M30).
No relationship between M30 count and age, sex, site (left vs right colon), Dukes stage, degree of dysplasia (adenomas), or degree of differentiation (carcinomas) was found. Cases in which the M30 count was more than twice the ISEL count or less than half the ISEL count were considered separately, but there were no correlations with any of the variables studied.
The results show that ISEL and M30 immunoexpression are correlated in adenomas and adenocarcinomas of the large intestine. However, there is a considerable scatter around the regression line (Figure 1), and it is clear that in any individual case the ISEL count does not necessarily predict the M30 count with any degree of accuracy. There are 2 possible explanations for differences between M30 and ISEL values in a given case. First, the techniques recognize different aspects of the apoptotic pathway. Second, the results of both tests depend on technique. In situ end-labeling in particular has been shown to be sensitive to the pretreatment step, which requires optimization for best results.[12] The overall counts are consistent with previous reports in the literature, which describe mean values of around 1% to 2% for adenomas and adenocarcinomas of the large intestine.[21-25] Some studies have shown higher[25-27] or lower[28,29] values, at least for some types of lesion; this phenomenon might be explained by differences in case selection, technical procedures, or interpretation of the histologic appearances.
In their report on M30, Leers et al[20] compared M30 expression with TUNEL and found that M30 expression was an earlier event in the apoptotic pathway than TUNEL positivity, and that TUNEL positivity persisted in late apoptosis with complete nuclear disintegration, although M30 became negative. However, a quantitative comparison between TUNEL counts and M30 counts was not presented in their article. My results are consistent with the onset of M30 expression preceding ISEL positivity, the latter remaining positive after M30 expression is no longer detectable.
Ki-67 is expressed in proliferating cells and is widely used to determine the growth fraction in tissue samples.[30] Although Ki-67 is superior to other proliferation markers in that it is not expressed during excision-repair of DNA,[31] it can be expressed in cells even when DNA synthesis is blocked, and can thus overestimate the proportion of actively cycling cells.[32] Studies have not shown any relationship between Ki-67 expression and prognosis in colorectal carcinoma.[30,33-35] Like other studies,[23,24,29] my results showed a correlation between the expression of Ki-67 and the apoptotic count, using both ISEL and M30.
In conclusion, M30 immunoexpression and ISEL positivity correlate strongly. Since M30 immunohistochemistry is technically simpler and easier to interpret than ISEL, it has the potential to become the method of choice for demonstrating apoptosis in formalin-fixed tissue for cells containing cytokeratin 18.
This study was supported by the Education and Research Fund of the Royal Hospital Haslar (Gosport, Hampshire, United Kingdom). The author is an Honorary Research Fellow at St Mark's Hospital (Harrow, Middlesex, United Kingdom) and thanks Ian Talbot, MD, FRCPath, for his comments and support.
[1.] Butler LM, Hewett PJ, Fitridge RA, Cowled PA. Deregulation of apoptosis in colorectal carcinoma: theoretical and therapeutic implications. Aust N Z J Surg. 1999;69:88-94.
[2.] Cummings MC, Winterford CM, Walker NI. Apoptosis. Am J Surg Pathol. 1997;21:88-101.
[3.] Staunton MJ, Gaffney EF. Apoptosis: basic concepts and potential significance in human cancer. Arch Pathol Lab Med. 1998;122:310-319.
[4.] Gorczyca W, Bruno S, Darzynkiewicz RJ, et al. DNA strand breaks during apoptosis: their early in situ detection by the terminal deoxynucleotidyl transferase and nick translation systems and prevention by serine protease inhibitors. Int J Oncol. 1992;1:639-648.
[5.] Mainwaring PN, Ellis PA, Detre S, Smith IE, Dowsett M. Comparison of in-situ methods to assess DNA cleavage in apoptotic cells in patients with breast cancer. J Clin Pathol. 1998;51:34-37.
[6.] Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of DNA fragmentation. J Cell Biol. 1992;119: 493-501.
[7.] Ansari B, Coates PJ, Greenstein BD, Hall PA. In situ end-labeling detects DNA strand breaks in apoptosis and other physiological and pathological states. J Pathol. 1993;170:1-8.
[8.] Gold R, Schmied M, Rothe G, et al. Detection of DNA fragmentation in apoptosis: application of in situ nick translation to cell culture systems and tissue sections. J Histochem Cytochem. 1993;41:1023-1030.
[9.] Wijsman JH, Jonker RR, Keijzer R, et al. A new method to detect apoptosis in paraffin sections: in situ end labeling of fragmented DNA. J Histochem Cytochem. 1993;41:7-12.
[10.] Mundle SD, Gao XZ, Khan S, et al. Two in situ labeling techniques reveal different patterns of DNA fragmentation during spontaneous apoptosis in vivo and induced apoptosis in vitro. Anticancer Res. 1995;15:1895-1904.
[11.] Hayashi R, Ito Y, Matsumoto K, et al. Quantitative differentiation of both free 3'-OH and 5'-OH DNA ends between heat-induced apoptosis and necrosis. J Histochem Cytochem. 1998;46:1051-1059.
[12.] Carr NJ, Talbot IC. In situ end labeling: effect of proteolytic enzyme pretreatment and hydrochloric acid. Mol Pathol. 1997;50:160-163.
[13.] Gold R, Schmied M, Giegerich G, et al. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab Invest. 1994;71:219-225.
[14.] Stahelin BJ, Marti U, Solioz M, et al. False positive staining in the TUNEL assay to detect apoptosis in liver and intestine is caused by endogenous nucleases and inhibited by diethyl pyrocarbonate. Mol Pathol. 1998;51:204-208.
[15.] Davison FD, Groves M, Scaravilli F. The effects of formalin fixation on the detection of apoptosis in human brain by in situ end-labeling of DNA. Histochem J. 1995;27:983-988.
[16.] Tateyama H, Tada T, Hattori H, Murase T, Li WX, Eimoto T. Effects of prefixation and fixation times on apoptosis detection by in situ end-labeling of fragmented DNA. Arch Pathol Lab Med. 1998;122:252-255.
[17.] Bardales RH, Xie SS, Hsu SM. In situ DNA fragmentation assay for detection of apoptosis in paraffin-embedded tissue sections: technical considerations. Am J Clin Pathol. 1997;107:332-336.
[18.] Sloop GD, Roa JC, Delgado AG, Balart JT, Hines MO 3rd, Hill JM. Histologic sectioning produces TUNEL reactivity: a potential cause of false-positive staining. Arch Pathol Lab Med. 1999;123:529-532.
[19.] Hawkins NJ, Lees J, Ward RL. Detection of apoptosis in colorectal carcinoma by light microscopy and in situ end labeling. Anal Quant Cytol Histol. 1997;19:227-232.
[20.] Leers MPG, Kolgen W, Bjorklund V, et al. Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis. J Pathol. 1999;187:567-572.
[21.] Moss SF, Scholes JV, Holt PR. Abnormalities of epithelial apoptosis in multistep colorectal neoplasia demonstrated by terminal deoxyuridine nick end labeling. Dig Dis Sci. 1996;41:2238-2247.
[22.] Ikenaga M, Takano Y, Saegusa M, et al. Apoptosis of colon cancers assessed by in situ DNA nick end-labeling method. Pathol Int. 1996;46:33-37.
[23.] Hao X, Du M, Bishop AE, Talbot IC. Imbalance between proliferation and apoptosis in the development of colorectal carcinoma. Virchows Arch. 1998;433: 523-527.
[24.] Koike M. Significance of spontaneous apoptosis during colorectal tumorigenesis. J Surg Oncol. 1996;62:97-108.
[25.] Ikenaga M, Takano Y, Ohtani Y, et al. Low levels of apoptosis and proliferative activity in colorectal villous tumors: comparison with tubular adenomas. Pathol Int. 1998;48:453-459.
[26.] Arai T, Kino I. Role of apoptosis in modulation of the growth of human colorectal tubular and villous adenomas. J Pathol. 1995;176:37-44.
[27.] Tsujitani S, Shirai H, Tatebe S, et al. Apoptotic cell death and its relationship to carcinogenesis in colorectal carcinoma. Cancer. 1996;77:1711-1716.
[28.] Tanimoto T, Tanaka S, Haruma K, et al. MUC1 expression in intramucosal colorectal neoplasms. Oncology 1999;56:223-231.
[29.] Takano Y, Saegusa M, Ikenaga M, Mitomi H, Okayasu I. Apoptosis of colon cancer: comparison with Ki-67 proliferative activity and expression of p53. J Cancer Res Clin Oncol. 1996; 122:166-170.
[30.] Kubota T, Petras RE, Easley KA, et al. Ki-67-determined growth fraction versus standard staging and grading parameters in colorectal carcinoma: a multivariate analysis. Cancer. 1992;70:2602-2609.
[31.] McCormick D, Chong H, Hobbs C, et al. Detection of the Ki-67 antigen in fixed and wax-embedded sections with the monoclonal antibody MIB1. Histopathology. 1993;22:355-360.
[32.] van Oijen MGCT, Medema RH, Slootweg PJ, et al. Positivity of the proliferation marker Ki-67 in non-cycling cells. Am J Clin Pathol. 1998;110:24-31.
[33.] Handa K, Yamakawa M, Takeda H, Kimura S, Takahashi T. Expression of cell cycle markers in colorectal carcinoma: superiority of cyclin as an indicator of poor prognosis. Int J Cancer. 1999;84:225-233.
[34.] Kyzer S, Gordon PH. Determination of proliferative activity in colorectal carcinoma using monoclonal antibody Ki67. Dis Colon Rectum. 1997;40:322-325.
[35.] Jansson A, Sun XF. Ki-67 expression in relation to clinicopathological variables and prognosis in colorectal adenocarcinomas. APMIS. 1997;105:730-734.
Accepted for publication July 14, 2000.
From the Department of Pathology, Royal Hospital Haslar, Gosport, Hampshire, United Kingdom.
Reprints: Norman John Carr, FRCPath, Department of Cellular Pathology, Level E, South Block, Southampton General Hospital, Tremona Road, Southampton, Hampshire SO16 6YD, United Kingdom.
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A sneak-peek into Marketing 101 breakfast event 'live' on 22 April
Find out what's in store at the 'Introduction to Marketing 101' not-for profit breakfast event on 22 April. What's different about our event?
1. You can listen to the experience of one of our own NFP peers live and face-to-face...
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Keeping your staff safer in 2015
Don't be the next Worksafe statistic. CommunityWest's launched its new Manual Tasks course developed especially for community workers with all the ingredients to help staff assess risks and avoid injury, balanced with just the right amount of theory and practice.
This new course covers what you need to know about back safety, postures and preventing injury presented in an informative and interactive way.
Help your 'Grapevine' grow
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The new log-in area can be found at the top right of our homepage in the green strip. Still can't find it? Read on...
Challenging community care: reporting on wellness
How did the Wellness Philosophy become a vital part of the Home and Community Care (HACC) Program in WA? This report written by CommunityWest's Hilary O'Connell chronicles the sector's journey to implement, adopt and embrace the approach. Find out more and download this free publication.
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YesStyle.com ships to the United States.
I ordered the Beige color sweater.
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I would recommend this product for kitty lovers and for the cold and snowy days :)
It is a cute sweater, a little boxy than i expected. The quality is OK


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Beware of utility scam asking customers for immediate payment
Fergus Falls, MN – Imagine receiving a phone call from your utility company or a collection agency saying that your electricity is about to be cut off even though you know you've paid your bill. The caller ID indicates that the phone number might be legitimate. The caller says, "I can stop this, but only if you pay me."
Are you a newspaper subscriber but you don't have a Digital Access account yet? https://secure.forumcomm.com/?publisher_ID=40&event=subscriber/lookup.
You will need your subscription account number and phone number. Not sure if you have an account? Email us at firstname.lastname@example.com and we can help you.


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- Exchange: OTC US
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Consumers Bancorp Inc+ Add to Watchlist
As of 20:10:00 ET on 03/31/2015.
Company Profile for Consumers Bancorp Inc (CBKM)
Consumers Bancorp, Inc. is the holding company for Consumers National Bank. The Bank attracts deposits from business and individual customers and uses such deposits to originate commercial, mortgage, and consumer loans. Consumers National operates in Stark, Columbiana, Carroll and contiguous counties in Ohio.
Contact Information
Consumers Bancorp Inc
Key Executives for Consumers Bancorp Inc (CBKM)
|Laurie L McClellanChairman/Dir:Investor Relations
|Ralph J Lober IIPresident/CEO
|Renee K WoodExec VP/CFO/Treasurer
|Phillip M SuarezExec VP/Senior Loan Officer
|Randy GilroySenior VP/Chief Credit Officer
|Bryan WaltersSenior VP/Manager:Risk
|Scott E DoddsSenior VP/Senior Lender
|Derek G WilliamsSenior VP:Retail Ops
|Theresa J LinderSecretary
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- $10 for one 7-inch layer cake (a $20 value)
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79 posts tagged with album.
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"But TO PIMP A BUTTERFLY. It's the American dream..."
Today, Kendrick Lamar's latest album, To Pimp a Butterfly, was released a week ahead of the release date. Yesterday, the album was briefly made available on iTunes (allegedly, the label's error). But enough of that - let's get to the music. [more inside]
I've traveled over dried earth and floods
It's been 20 years since PJ Harvey emerged from a time of isolation and song writing that produced the album To Bring You My Love.
Do you read Sutter Cane? No? Oh, he's good, check him out. Well, bye
The Wall Street Journal celebrates the 20th anniversary of John Carpenter's In The Mouth of Madness. Meanwhile, at VICE, John Carpenter wouldn't explain his new album, so they got a bunch of artists to each provide their own interpretation.
The music behind the worst album covers (SLYT, partially NSFW)
Some of the music is worse than the worst album covers, which you'd think would be difficult [via]
listen to this in the dark and you will LOSE YOURSELF
The Morning News' Andrew Womack's Top Albums of 2014, with help from youtube commenters. (mlyt + Spotify and Rdio playlists)
Merry Christmas from the "Sesame Street" Family, 1975
Song for an old-fashioned Christmas: "'Twas the night before Christmas on Sesame Street/And the people were sleeping, 'cause the people were beat/The snow had been falling for most of the day/And it lay over everything, sooty and grey..." -- as performed by Sesame's own David (lyrics) for the 1975 album "Merry Christmas from Sesame Street" (cover; inside artwork; back cover). Please join me (and Bert and Ernie and Oscar and Big Bird and others) in revisiting a holiday classic. [more inside]
Of bells, harps, accordions, the kalimba and a saw: amiina
If you've encountered delicately uplifting chimes and bells or a singing saw, seen the contributions of a string quartet in a Sigur Rós video, heard the last recording by Lee Hazlewood and noticed the gentle singing and music, or listened to Yukihiro Takahashi consider words, then you've possibly encountered the Icelandic band amiina. [more inside]
Left to Our Own Devices
After dropping sweet synthwave tunes for two years, Le Cassette have released their first album "Left to Our Own Devices," available on (of course) cassette tape
If you were watching late-night television in July 1998 you may have seen the half-hour informercial parody that the Beastie Boys produced to promote their upcoming album, Hello Nasty. The ad features Mike D, MCA , and Ad-Rock taking on roles to shill everything from the services of phone psychics to get-rich-quick scams to a food processor that plays songs from the upcoming LP. (Warning: video auto-loads.) [more inside]
Have A Cow, Simpsons Fans.
"The Yellow Album isn't an album so much as the most dramatic test of a true believer's faith since God asked Abraham to sacrifice Isaac. The album dares Simpsons diehards like myself to make it through a harrowing 48-minute gauntlet of ill-considered covers, train-wreck collaborations (Lisa and P-Funk All Stars: oh, it happened), generic synth-pop grooves, and jokes that would be killed in Jay Leno's writers' room for being insufficiently edgy. " - My World OF Flops on the bizarre, unloved Simpsons cash-in, "The Yellow Album. " complete with sample tracks.
Try Not To Think Of Christopher Cross
While best remembered for his starring role in a horrible movie, once upon a time, the man had some chops. A surprising mix of world-tinged fusion and straight ahead jazz from 1969, I give you:
"The Dudley Moore Trio"
"The Dudley Moore Trio"
Laura Marling
Singer-songwriter Laura Marling will release her latest album, Once I Was an Eagle, this May. She's shared a first song off of it, "Where Can I Go?" [more inside]
Wuthering Bytes
Kate Bush album covers, reimagined as ZX Spectrum artwork. [more inside]
Perfection Is Perfected
Dec 15th, 1992 : The Chronic, Dr. Dre's first solo album, is released. [more inside]
Houses of the Holy
Creating Art from Failure. Take one epochal album by one of rock's legendary bands (called "one of the dullest and most confusing albums I've heard this year" by Rolling Stone on its release.) Name it after the nickname the band has given the venues where they appear, and for which they had written a song, which they neglected to put on the album itself. And then there's the album cover ... [more inside]
"Etta James Rocks The House"
On September 27, 1963, at the New Era Club in Nashville, Tennessee, Etta James rocked the house. The result was "simply one of the greatest live blues albums ever captured on tape". [more inside]
More music from Mishka
You might have seen the hours of music from Bloglin last year, but Мишка ("Mishka," or "bear cub" in Russian) has another treasure trove of music: free albums, anthologies, and mixtapes on Bandcamp. They started a bit slow with a single mixtape in 2009 from Ninjasonik, and 2010 wasn't too active. But in 2011 they had 9 releases, and already 14 in 2012, the newest being the debut album from 19-year-old nu-disco producer Cream Dream. A handy rundown of the releases to date below the fold. [more inside]
Sing us a Song to Keep us Warm, There's Such a Chill
In the wake of their grunge-y breakout hit "Creep" and the success of sophomore record The Bends, Thom Yorke and the rest of Radiohead were under pressure to deliver once more. So they shut themselves away inside the echoing halls of a secluded 16th century manor and got to work. What emerged from that crumbling Elizabethan castle fifteen years ago today was a shockingly ambitious masterpiece of progressive rock, a visionary concept album that explored the "fridge buzz" of modernity -- alienation, social disconnection, existential dread, the impersonal hum of technology -- through a mosaic of challenging, innovative, eerily beautiful music unlike anything else at the time. Tentatively called Ones and Zeroes, then Your Home May Be at Risk If You Do Not Keep Up Payments, the band finally settled on OK Computer, an appropriately enigmatic title for this acclaimed harbinger of millennial angst. For more, you can watch the retrospective OK Computer: A Classic Album Under Review for a track-by-track rundown, or the unsettling documentary Meeting People is Easy for a look at how the album's whirlwind tour nearly gave Yorke a nervous breakdown. Or look inside for more details and cool interpretations of all the tracks -- including an upcoming MeFi Music Challenge! [more inside]
I declare IDGAF the Song of the Summer 2012
George Watsky ("Pale Kid Raps Fast") has released a new free 16-track mixtape. First single: Rich Girl, based on the Hall and Oates song of the same name.
The Wrecking Crew
Bands often don't seem to be able to play on stage the way they did on their album; and we accept that for a lot of reasons having to do with the conditions, the production facilities and the sheer number of takes that were probably involved. But for a whole generation of hit music, there was often a more basic reason: it wasn't them playing on the album in the first place.
For nearly a decade, if you were an L.A. producer and you wanted to record a hit single, you'd call in The Wrecking Crew. Members of The Byrds, The Beach Boys, and The Mamas and the Papas would step aside as The Wrecking Crew laid down the instrumental tracks. Then, the members of the main band would come back to add the vocals on top.The above link goes to the OPB radio story I listened to this morning, with an embedded player. Official site for the book.
A 10 Minute Shoot
There's a law in New York state about driving with a live moose on the hood of your car
Here (from NPR's All Things Considered, 2008) is Woody Allen's classic stand-up routine, the Moose Story. A few more, from YouTube: Science Fiction Film, Eggs Benedict (unfortunately with distracting animation), on the Jack Paar show. MLYT [more inside]
Boom Bip: from abstract hip-hop to spooky sounds of black magic from the turn of the 19th century
Bryan Hollon, better known by his musical handle Boom Bip, is probably recognized for two drastically different sounds: abstract hip-hop from his early Mush Records days, and his Mercury Prize-nominated Neon Neon collaboration with Gruff Rhys. Add to that a new inspiration: black magic from the turn of the 19th century. What does that sound like? Let Boom Bip walk you through his new album, Zig Zaj. Step behind the deep red velvet curtains for a peek at the history of Boom Bip. [more inside]
Here comes a Lion... oh yes, it's a Lion...
Nants ingonyama bagithi baba! It's been nearly two decades since that glorious savanna sunrise, and once again The Lion King is at the top of the box office. It's a good chance to revisit what made the original the capstone of the Disney Renaissance, starting with the music. Not the gaudy show tunes or the Elton John ballads, but the soaring, elegiac score by Hans Zimmer which, despite winning an Oscar, never saw a full release outside of an unofficial bootleg. Luckily, it's unabridged and high-quality, allowing one to lay Zimmer's haunting, pulse-pounding, joyful tracks alongside the original video (part 2, 3, 4), revealing the subtle leitmotifs and careful matching of music and action. In addition, South African collaborator Lebo M wove traditional Zulu chorals into the score, providing veiled commentary on scenes like this; his work was later expanded into a full album, the Broadway stage show, and projects closer to his heart. Speaking of expanded works, there were inevitable sequels -- all of which you can experience with The Lion King: Full Circle (download guide), a fan-made, three-hour supercut of the original film and its two follow-ups. Want more? Look... harder... [more inside]
Dad, what's an album cover?
Coversmart: The first music trivia website dedicated to the art of album covers. [more inside]
Ladies And Gentlemen, The Kronos Quartet
In their 25 year career San Fransisco-based Kronos Quartet might be most famous for creating the go-to dramatic movie trailer music but they've recently courted controversy with their latest album, 9/11, with Steve Reich (NPR First Listen). The album is another in a long line of collaborations with composers such as Phillip Glass, Terry Riley, and Pēteris Vasks. And like any good instrumental ensemble, they've covered Hendrix, Sigur Ros, and Tom Waits. Oh, and they've been on Sesame Street. [more inside]
Egg City Radio: Post-Punk Junk over easy
Egg City Radio is what became of the great Post-Punk Junk blog [previously]. And it's still a treasure trove if you're looking for shared out-of-print albums and live sets--not only from Post-Punk but also many other genres as well. [ECR previously (via), -er, -est]
What's in Apollo 18's name?
The movie Apollo 18 opened recently. The plot centers around a supposedly secret Apollo moon landing mission (the last actual mission was Apollo 17). But never mind the space stuff, what is up with the title of the mission? It's been used for a couple of non-space related music projects. They Might Be Giants used it for the title of their fourth album. Then there's a Korean indie rock band with the name, who won the Rookie of the Year award at the 2010 Korean Music Awards. [more inside]
Headless Corpses, Stolen Laptops, and Lawyer-shaped Guns.
What has Richard Buckner been up to, since 2006's Meadow? [more inside]
Like, I want some bread up front.
Once upon a time, Van Morrison had a record contract with Bing Records which he wanted to escape. Since the contract required him to produce thirty-six original songs, Van Morrison sat in the studio for a single session and recorded a series of nonsensical non-tunes that are still in his distinctive style. Three of them are available here.
"Art is an invention of aesthetics, which in turn is an invention of philosophers.... What we call art is a game."
What If Your Favorite Album Was a Book? Rock classics from from Arcade Fire to Zeppelin, reimagined as book covers. [more inside]
Morgan Fisher's Miniatures - The Blog
To celebrate the 30th anniversary of his awesome abstract compilation album Miniatures, Morgan Fisher (of Mott the Hoople fame) has started going through the 51-track masterpiece from the beginning in, well, minute detail, updating readers on the current status of the featured band, providing relevant links, explaining his compilation process, and, of course, streaming each track. So far the first 7 tracks are featured, but start here with the bonus track added to the 1994 CD re-issue of Miniatures – "The Miniatures Miniature". [more inside]
Iconic 70s and 80s Americana
Richard Amsel was a Philadelphian artist who created original and iconic illustrations and paintings found on posters for several popular 1970s and 80s American movies, including Mad Max: Beyond the Thunderdome, The Dark Crystal, Raiders of the Lost Ark, and The Sting. He also created unique artwork for TV Guide covers, as well as album cover art for Bette Midler and others. His Time cover featuring Lily Tomlin was added to the permanent collection of the Smithsonian Institution.
Decemberists gonna December
Goes well with randomly generated music
Teach me to meet my desires with some grace...
Interpol have a new, self-titled album coming out September 7 (the 13th in the UK). Hey, guess what! It sounds like Interpol, so this is the kind of thing you will like, if you like this kind of thing. "Lights" (and here in HD) already has me imagining doing a thousand-yard stare out of a bus window on a cold, late November night. The second video, "Barricade" is here (and here in HD).
Like a Mars Volta album that you can play to your parents
Omar Rodríguez López of Mars Volta fame has released an album in collaboration with the wonderful John Frusciante which sounds exactly like you imagine it would. It's available as a name-your-price download (also for free) and any amount you pay will be donated to a good cause. Frusciante was also involved in López' latest production which is available under the same conditions.
Preferred activity: blowin' or a-changin'?
The Answer, My Friend. Your own personal Best Bob Dylan Album calculator.
The Fetishising of Tape Begins Now
"I only listen to cassettes," Sonic Youth's Thurston Moore told CBC radio last summer: an article on the merits [or otherwise] of releasing new music on cassette. [more inside]
The Kleptones, mashup artists behind previously-posted albums such as A Night At The Hip-Hopera and 24 Hours, have just released their newest entitled Uptime/Downtime. In a word, it rocks.
Sounds from Nine Countries
9 Countries was recorded on location in Indonesia, Thailand, Cambodia, Laos, Myanmar, Tibet, India, Egypt and Greece between October 2005 and March 2007 by Tom Compagnoni. What you hear has been entirely assembled from these field recordings, no additional samples used.
A mashup / sound-collage / ambient / documentary album by Wax Audio.
A mashup / sound-collage / ambient / documentary album by Wax Audio.
Industry's down think I've died and I've flown away
Shareese Renée Ballard, or Res, put out an album in 2001 titled How I Do. Santi White, a.k.a. Santigold (formerly Santogold) helped out with the lyrics. A mix of R&B and rock, How I Do scored one hit single, "They Say Vision". Label politics stalled the release of her second album, so Res was let go from her contract. After touring with Gnarls Barkley and forming Idle Warship with Talib Kweli, Res continued to write and record. Putting together new songs with material from her unreleased album, she posted Black.Girls.Rock! on her website for free. (MP3 ZIP, PDF Booklet.) [more inside]
Classical humour
Westminster Gold reissued classical albums in the seventies. The covers could be racy [slightly NSFW], unusual, puzzling, irreverent, and employ national stereotypes, but my favourites are the literal puns like Pops Promenade and Allegri String Quartet.
"He takes a $1.98 tape into Folsom Prison and comes out with an album."
"Hello, I'm Johnny Cash." On January 13, 1968, Johnny Cash played two concerts at Folsom State Prison with June Carter, Carl Perkins, the Statler Brothers, and his band, the Tennessee Three. At Folsom Prison, drawn mainly from the first show, is often ranked as one of the best albums of all time and turned Cash's career around. Reporter Gene Beley covered the concert and recorded some songs from the audience. [more inside]
In This Light And On This Evening
To promote their soon-to-be-released album, In This Light and On This Evening (coming October 27), British indie rockers Editors have made an interesting hack of Google Maps Street View. If you go to the Editors website here, you can wander through the streets of London looking for landmarks set out by the band. [more inside]
Rubik cubes and classic album covers by the Beatles and the Clash.
It's Seurat by me. Iconic album covers by the Beatles and the Clash. Mixed media (a metric buttload of Rubik's cubes shown in Dailymotion video). (via)
Hair Metalski
70s/80s Soviet album covers. Until today, I had no idea Soviet hair metal existed. Prepare for keytars, mall hair and proof that 80s cheese was not solely a product of degenerate kepitalist decadence.
Wilco (the stream)
Wilco has just started streaming their new album, Wilco (The Album) The band has done this since Yankee Hotel Foxtrot and is asking those who download the entire thing to donate some cash to The Inspiration Corporation charity in Chicago.
unknown pleasures
He Who Hesitates is Disincentivised
Omaha rockers Cursive are selling their new album for just $1... No wait, it's $2... $3... $4... WTF?? In yet another twist on the whole, name-your-price (Radiohead), fan-financed (Jill Sobule), take-shrooms-and-cruise-hollywood (Josh Freese) tiered pricing experiment being carried out by what's left of the music industry, Cursive are increasing the price of their new record by $1 each day until its "official" release. Given the popularity of sites like Did it Leak (and the corresponding file-sharing forums that I won't link to here) it seems to me like this is a pretty good way to reward well-intentioned but impatient fans who might otherwise resort to less honorable means of getting the latest stuff from their favorite bands. Or maybe it's just another hare-brained scheme that will only hasten the end of record labels as we know them. Either way, they got my $1... And that was after I already got my hands on the mp3s!
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Imminent Destruction, NWO G7 Nuclear Summit, EMPs and Global Thermonuclear War
in Religion
Imminent Destruction, NWO G7 Nuclear Summit, EMPs and Global Thermonuclear War
Join Kenneth, John and Cathy in the chat room while they discuss a staggering portfolio of prophetic and empirical evidence all leading up to the inevitable global financial collapse (Third Seal), and World War 3 (Fourth Seal) as we move rapidly toward the unraveling of the Sixth Seal (comets, earthquakes, and three days of darkness) and the rapture of the Bride of Jesus Christ. Tonight we will attempt to present elements from a wide array of disparate sources weaving a powerful message of a world about to explode.
God Bless You - See you there!
Conversations with the Sexes feat G7 and AshBeeezy Breezy
PARENTAL ADVISORY!! ADULT TOPIC, NO LISTENERS UNDER 18!!! SPECIAL GUEST TONIGHT: GetUpRadio.com AshBeezy Breezy will co-host along side G7 tonight!! Tune in for their HOT Conversation Topic, New Music by Derty Harry, GetUpRadio.com announcements and more!!
CALL IN or share your thoughts in CHAT ROOM! Tune in every week to iLAST Radio's most POPULAR segment: Conversations with the Sexes formerly known as iLast Radio's Battle of the Sexes!! It's a NEW SEASON, get on board and TUNE IN Live with Mz DeeVa and G7 aka The 7th Letter!!! Sunday nights 10pm CST. Call in line is 347-945-6968
another conversation between jeff beller and j.w. smith
in Energy
jeff and j.w. continue their conversation: parallel concerns and differing solutions make for a lively exchange of ideas. please feel free to contribute your thoughts, 347-215-6731. both jeff and j.w. see that the 'old school' socio economic and political systems are breaking down, they cannot hold up under the demands of the future. the most important demand of these being human rights and the preservation of the natural world. both men offer ideas and structures for the 'back up plan'. also - " 133, g7 nations vow to distroy americas new world order!" , j.w.smith - tune in to hear j.w. expand on this...
Martus Ministry - "Eye of The Storm"
in Politics
Babylon Prophecy in Iraq? True Prophecy vs False Prophecy, Obama and his peace treaty in prophecy, World War III, Battle for the New World Order, G7 vs BRICS, The Current Cold War and NATO, Pestilences, Famines, "Let us remember and not forget", and more!
For more information go to http://www.MartusMinistry.org
Breaking Prophecy News; Not Really So Obscure, Part 4 (TPDR #411)
in Religion
PROPHECY HEADLINES: Saudi Arabia reports over 100 more MERS infections, 92 more deaths | G7 leaders express concern, resolution over conflict in Southeast Asia | Gallup poll: Divorce, gay sex, fornication see higher levels of 'moral acceptability' in U.S. | 5.7-magnitude earthquake shakes Alaska | South Sudan on the brink of brutal famine; 3.5 million suffer from food shortages
PROPHECY BOOTCAMP: "Not Really So Obscure (Part 4)" from Dr. Tim LaHaye
The Pre-tribulation Rapture in One Chapter
Second Thessalonians 2:1-12 mentions the rapture, Tribulation, and glorious appearing in one chapter. In verse 1, the words "the coming of our Lord Jesus Christ" speak of Christ's return to earth. They are followed by a conjunction that is usually translated "and," but which can also be translated "even." In either case, Paul refers to "our gathering together to Him." The term "second coming" is a reference to the entire coming of Christ, which includes the two phases separated by seven years. The phrase "our gathering together to Him" cannot mean the glorious appearing, since that is when all living creatures are gathered to Christ for the judgment of the nations and the establishment of His kingdom. So in verse 1 we have both the glorious appearing and the "gathering together to Him" (the rapture).
The people described in 2 Thessalonians 2:9-12 are unsaved people who go into the Tribulation because they heard the gospel but refused to believe because they "had pleasure in unrighteousness." ...
OCCUPY TILL I COME: Gaining Hope from Bible Prophecy (Part 8) by Dr. David Reagan.
MUSICAL SELECTION: "The King is Coming" by Newsboys
Martus Ministry - "Eye of The Storm"
in Politics
The Antichrist Peace Treaty in Israel, World War 3 in prophecy, G7 vs BRICS fight for the New World Order, Fallen from Grace?, Border crisis and New World Order agenda, "COMFORT IN GRIEF BIBLE VERSES" and more!
For more information go to http://www.MartusMinistry.org
IceBERG, DAHLing!
We are adrift at sea and we've already hit the berg. Will we go down? Eventually, but it need not be now if Americans can be inspired to course-correct. We can't go back and if go forward on the current course–we're sunk. We need to revisit, restore and reapply the blueprint for these United States.
We haven't applied the Constitutional blueprint in more than 100 years; we're taking on water. The captain is a fool and the crew is an embedded bureaucracy of fools. The passengers have been numbed into complicity, passivity and ambivalence. In a high-pressure, stressful situation only cool heads with solid plans and the courage to execute them survive.
The media is controlled by corporations in bed with the government. The 'prisoner' exchange of 5 Taliban for 1 deserter is a legitimate story, but it is being used to obfuscate importantnews and pitting red team fans against blue team fans in a game of DISTRACTION!
Are you going to help them rearrange the deck chairs on a ship that has struck an iceberg and doesn't have enough lifeboats, or are you going to do your best to man the stations with those who understand the Constitution and defend liberty. It is an iceberg, dahling and most of the damage is below the waterline. Don't yell abandon ship or wait for a response to our distress call–get off your butt and fix it NOW!
Tyranny is assured UNLESS liberty-loving people set aside their differences and band together against the rising tide of statism. Conservatives and libertarians MUST work together to ensure the restoration of constitutionally limited government–it is up to you. End the imperialist police state and to defeat the Democrat-Socialists-first you MUST CRUSH the RINOs, for liberty!
Please LIKE and SHARE our Facebook page: https://www.facebook.com/LibertysThunder
Martus Ministry - "Eye of The Storm"
in The Bible
G7(7 Heads) vs BRICS , New World Order, World War III, P2 Lodge Cold War, Pope Francis and the Mark of the Beast agenda from his twitter, "Afraid of being the 'Christian Kook'?" And more!
For more information go to http://www.MartusMinistry.org
What is going on?
in Religion
What is going on? Nation against nation, floods, earthquakes, murder, fear, destruction, blood moons, and death. Are these signs of the end of the world? What does the Bible say?
Join us as we find our answers and peace in God's Word.
Martus Ministry - "Eye of The Storm"
in The Bible
The New World Order , G7 the 7 heads , World War III updates , Wars and Rumors of Wars, The signs of the preparation of the 144k and the Next Exodus, Vatican and child trafficking, Obama and the Muslim Brotherhood, "Are We Shining Bright, Dim, or No Light?" and more!
For more information go to http://www.MartusMinistry.org
Martus Ministry - "Eye of The Storm"
in The Bible
World War III and the Seals of Revelation , G7 the 7 heads of the beast , Obama the Antichrist, Two State Solution , Ukraine and Russia updates, "Distraction = destruction" and more!
For more information go to http://www.MartusMinistry.org
Coming Apocalypse
More people missing in Washington State as 14 confirmed dead and 176 missing as a "Mega Mudslide" melts the mountain side. Also a Cyclone Gillian is now headed toward the Malaysian Airplane search site as the prayers go up for the familys of the missing. Also Over 300 earthquakes have hit Chile in the last week causing "apocaliptic" fears in Chile. Also United Kingdom Hospitals have been using aborted babies to burn an incinerators to heat the Hospitals. Also The G8 Summit has just kicked Russia out of the meetings changing the location from Sochi, Russia to Brussels and now will be known as the G7. Alaska petition is seeking to leave America and secession to Russia has now got 21,000 signatures. Also more current news events along with bible prophecy and the powerful Word of God. Your host Pastor Paul Begley of Indiana.
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It's difficult to find versatility, functionality and support in a sandal, but the Women's Naot Kyra seamlessly incorporates these three fundamentals! The distinct deep-sea leather hue and striking jewel accents will jazz up jeans or your favorite sundress, while simultaneously empowering your lower extremities with improved balance. These summertime slip-ons come with a deep heel cup and slip-resistant tread for optimized traction control.
Naot Kyra Attributes:
Please Note: As these sandals are part of the Low Scandinavian Collection, they use a Scandinavian Replacement Footbed, which can be found here.
Naot has great footbeds. I bought these to dress up and dress down, love the accents. A little too wide for my liking.
Absolutely stunning sandal and also very comfortable. The decoration is very tactful and makes this little shoe beautiful! I really think this is one of the greatest pair of sandals I have ever purchased!
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"In the early part of 2013 I noticed all styles of MBT shoes on clearance. MBT had just gone out of business, their remaining shoes being sold off. Now what was I going to do for shoes? I stand 10-14 hours per day on my feet. Because of this abuse I developed bone spurs in each heel, and plantar fasciitis. Walking anywhere, any distance is painful, difficult. MBT shoes were recommended to me by other people with similar problems. Wearing these shoes have made it possible for me to walk in comfort again. They are the only reason I can stand or walk. Fast forward to the new MBT shoes produced by the company that bought the old MBT: They're great! Not as butt ugly as the old styles. Just as comfortable and super fun. They still run a little small. I hope they continue to make a size US 12 for the winter, I need that size for close toe boots. I have a serious MBT habit. Keep 'em coming guys."
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text: Dr. James D. Hardy of the University of Mississippi in Jackson attempted the first heart transplant from a nonhuman primate -- a chimp named Bino -- into a human. The patient was 68-year-old Boyd Rush. After only 90 minutes, the heart stopped functioning because it was too small to maintain circulation on its own.


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|Meet Chrome Next in Web Browser Discussion & Support
|Xbox One Preview Program in Microsoft Console
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Posted 14 June 2013 - 22:03
Posted 14 June 2013 - 22:09
Posted 14 June 2013 - 22:22
That is dumb. Like it or not you need good credit. Credit cards are a great thing, just don't be an idiot with them. Its not that hard.
Posted 14 June 2013 - 22:45
Credit cards are a great thing...
Posted 14 June 2013 - 23:09
You can have and get great credit and never get a ripoff card, it's only purpose is to keep you in debt indefinitely
Same here but what would I borrow for? Seriously my parents have never borrowed anything in their lives.
Posted 14 June 2013 - 23:12
Erm say what why the hell would I need credit im not American but its a similar thing here in the UK older people all have credit us young people im 22 nearly (long an adult in this country) don't and won't ever have one. Why would I need a credit card or good credit ill just live with what I earn.... seriously enlighten me I don't expect to need a credit history to get a mortgage should I even want one.
Posted 14 June 2013 - 23:17


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: Tears For Fears Pale Shelter Music Videos
Artists, Albums, Songs and Music Videos
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Tears For Fears Pale Shelter, 1983, Live HD 720p
a track from my own individual list ''alltime best 100 songs''
Tears for fears - Pale Shelter (Live)
This video is the only and original HD version of this song from internet! This is the re-recorded v
tears for fears - pale shelter live 83
Live at Rockpalast 1983, sung by Curt as last encore.
Tears For Fears - Pale Shelter (Hammersmith Odeon, 1983)
Tears For Fears performing "Pale Shelter" at Hammersmith Odeon in 1983.
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Elizabeth Nowicki
Deaths, Kids, Pregnancy / Paternity, Suicide
In Defense of the Suicidal Columbia Law Mother
A friend of Cynthia Wachenheim, the lawyer who jumped to her death while cradling her baby, speaks up in her defense.
Deaths, Kids, Pregnancy / Paternity, Suicide
Attorney Jumps To Her Death Cradling Her Baby; The Baby Is Fine
Sorry, I can't be sympathetic for the woman who jumped out of a window with her infant strapped to her chest…
David Sparks on Starting His Solo Practice:
If the thought of opening a solo practice is both exciting and scary, we have a treat for you. New Solo, a podcast dedicated completely to solo practitioners, is here to help. Each month, host Adriana Linares interviews distinguished guests who share insights and information on how to successfully run your own law firm.


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Showing reviews 1 - 20 of 35
soup bag"
by Mrs Taylor
Fab way of storing & freezing soup as I make so much soup when vegetables are special offer and give to my family as we are all soup eaters. Saves so much storage in your freezer and from your freezer straight to the microwave.
Published 02 01 2015
great idea"
by Mrs westcott
I use these bags a lot, great for freezing sauces and soups.
Published 31 12 2014
Really useful bags"
by Sandy
I make batches of soup, bolognese sauce etc and freeze them in batches. These bags are so easy to use and are really useful for all sorts of things.
Published 11 02 2014
Great idea - need smaller sizes"
by Debra
This is my second purchase and they are great. I mainly use them for leftover gravy and sauce where it's just enough for one more meal or perfect as gravy for sausages or chops BUT it would be even more great if they came in 500ml or 300 ml sizes for this use :)
Published 17 12 2013
Other uses"
by JANET
These bags are great for freezing soups but I also use them to keep awkward shaped things like melon in, in the fridge. Another use is for putting travel liquids in when flying as they make a good, simple toilet bag that sits steady in a hotel bathroom.
Published 11 11 2013
This review is for an older version of this product
by Katherine
These bags are brilliant, but I really miss the 1.5ltr bags, which are especially brilliant if you make large batches or have a large family. Please bring them back for Autumn/Winter 2013/2014!
Published 19 06 2013
A note from the team: We've passed on your suggestion to our buying team to consider bringing the 1.5ltr bags back. Keep your fingers crossed, you never know!
Excellent bags"
by Peters
I've been buying these for years. They are not only good for soups but for freezing anything that has a liquid element - casseroles, sauces etc. They are easy to fill because of the gusset, and sturdy so they don't tear. I buy several packs once a year and then make bulk quantities of chilli, ragu sauce etc for the freezer.
Published 07 06 2013
This review is for an older version of this product
Bring back bigger size"
by Sandra
I use these often for homemade soup but find the 1 ltire size a tight squeeze for our portion sizes. Also I found the larger bag easier to stand upright for filling when alone, I now need to get other half to assist when filling.
Published 25 03 2013
great for students"
by antoinette
these are very sturdy and reusable. I have 2 guys in college and these are very useful for freezing soups and portions of stews and casseroles for their freezer and good use of freezer space. I am ordering 2 more packs.
Published 28 01 2013
Great bags"
by Dinah
Very robust, easy to use and leak proof. Label writes easily.
Published 17 01 2013
soup 'n' sauce bags"
by Andrea
I use these soup 'n' sauce bags all the time for my freezer. I want to express my disappointment that the 1.5 litre bags are no longer available. The larger size is much more convenient for freezing soup.
Published 03 12 2012
A note from the team: Thanks for taking the time to write your review. I'll be sure to pass on your bring back request for the larger sized bags.
by Ruth
Don't know how I did without these.. they are fab for everything especially homemaade soups and sauces! Excellent will be purchasing more Thanks lakeland !
Published 12 09 2012
by EDITH
Strong, easy to use and reusable without any problems with the closure seal. Able to take 4 generous portions of soup. wish I'd bought them sooner.
Published 10 09 2012
Are the 1.5 litre bags back?"
by Helen Walls
The description on the online catalogue states that they are available in 1.5 litre size, but when I tried to order them I cannot find them. These bags are great but 1 litre is not big enough for my family. Please bring 1.5 litre bags back.
Published 20 08 2012
by JUNE
These are great! Have used them often as I usually make more soup than is needed - so there is always homemade soup in the freezer. Thank you Lakeland!
Published 02 07 2012
Great Product..."
by Jonathan
... but I also want to see a return of the 1.5 litre bags, please
Published 11 06 2012
A note from the team: Thank you for placing your review. We're pleased you like this product and have passed on your suggestion to our buying team to consider.
Soup 'N' Sauce"
by Mrs Donohue
Sturdy, space saving & leak-free. Please Lakeland - bring back the 1.5l size - much better for larger families, or just those of us with larger appetites!
Published 11 06 2012
A note from the team: Thank you for placing your review. We're pleased you like this product and have passed on your suggestion to our buying team to consider.
multi use!"
by patricia
these bags are not only brilliant for soups etc but when going on holiday they are totally safe to put in your liquids - shampoos, mouthwash etc without fear of leaks into clothes. fab -u -lous !!!
Published 21 05 2012
If you cook, you'll need this"
by Ms Chan
I am always on the look-out for efficient and money-saving products. Soup n' Sauce Bags meets both criteria. It allows me to cook in large quantities then store the food tidily, in suitable portions, and labelled clearly. Because of this I can also take advantage of supermarket promotions, to buy fresh ingredients in family-size quantities, which would otherwise be too much for the two of us. Another benefit it brings is that I can work or go out without worrying about my husband's dinner, knowing that there are home-cooked meals stocked up, so he would not need to order take-away.
Published 21 05 2012
Soup N Sauce bags"
by YVONNE WHITEHEAD
This is a very usefull product, I use them all the time to store sauces as they take up very little room in the freezer but I found that the 1.5 Litre size more usefull. Will this make a comeback.
Published 28 04 2012
A note from the team: Thank you for placing your review.We're pleased you enjoy the soup and sauce bags and have put your suggestion to bring back the larger version to our buying team. Thank you for your time and feedback.