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©2015 mamasemptynest.wordpress.com
Author: Mama's Empty Nest
Expressed in love
Some of us are loud. Some of us are quiet. Some of us use bold gestures and words. Some let others speak for us.
Some of us 'speak' without words through art, music, work, the way we dress, what we eat, and the list could go on and on. When it comes to expressing ourselves, the ways we do so are as diverse as the myriad hues of color. Variations upon variations.
This week's photo challenge – Express Yourself – caused me to think about how I express myself. I'm a communicator. That's why I love words – both spoken and written. Expressing myself is one reason why I write this blog.
But I also express myself through the lens of my camera.
"The camera always points both ways. In expressing your subject, you also express yourself." ~ Freeman Patterson
I do imagine that my photos speak for me, describe me, help the viewer get a sense of who I am even without me expounding on them. That's why I enjoy Wordless Wednesdays so much.
What we do truly does demonstrate who we are. And just like everything in this world, our actions can be positive or negative. We can encourage others through our self-expressions or tear others down.
This morning I thought about my family since they are an expression of me and how each one of them depicts themselves. And I thought I'd give you a glimpse into their expressions.
Oldest daughter expresses herself through music, she's a talented pianist, but she also reveals who she is through her love of adventure in travel.
Son also demonstrates himself through music. A self-taught guitarist, he reveals his engineering side through this cigar box guitar he fashioned that really makes beautiful music.
Middle daughter is musical too, she sings. But how she really reveals herself is through emotions and you can usually see that through her facial expressions.
Papa shows who he is by his works of service from his involvement in a community civic organization to the many ways he serves others in our church. That's how he expresses himself.
But it occurs to me that none of our self-expressions mean a thing if they are based only in self, done to glorify self, to exalt ourselves, to bring attention to self. Because when we focus on self, how can we express love? Self-love maybe, but certainly not love for others.
For me, expressing myself needs to have a backbone and that backbone is faith in my Savior. Faith expressed in love.
"I suspect you would never intend this, but this is what happens. When you attempt to live by your own religious plans and projects, you are cut off from Christ, you fall out of grace. Meanwhile we expectantly wait for a satisfying relationship with the Spirit. For in Christ, neither our most conscientious religion nor disregard of religion amounts to anything. What matters is something far more interior: faith expressed in love." ~ Galatians 5:5-10 The Message (MSG)
That's how I want to express myself. Faith expressed in love.
What about you? In what ways do you express yourself? How does that show us who you really are?
"Self-expression must pass into communication for its fulfillment." ~ Pearl S. Buck
©2015 mamasemptynest.wordpress.com
That place called serenity
When you first see the word serenity, what thought comes to your mind?
Peace. Tranquility. Calmness. That's the pleasant path that word takes me down. This past week, the photo challenge theme has been this word. Serenity.
If serenity were a place, where would it be?
For some, it might be seaside. Basking in the sun on a sandy beach somewhere with the steady rhythmic roar of ocean waves lolling you to sleep.
For others, it might be standing on a mountain top after a long, strenuous climb just soaking in a magnificent view around you.
Still others might find serenity in the midst of a deep wooded forest surrounded by grand towering trees where the only sound might be the gentle rustle of leaves when a whisper of wind comes along.
Maybe serenity is found in your own backyard garden or thousands of miles away at your favorite vacation destination. Serenity might not even be a real place but instead a spot that only exists in your imagination.
It started snowing this week, enough to accumulate a bit. We haven't had a lot of snow this winter season so far, not like some years. Of course, winter isn't ready to call it quits just yet. Some of our biggest snowfalls in the last few years have descended upon us in February.
But snow silently falling on everything in sight gives me a peaceful feeling. I love to watch snowflakes dance through the brisk, cold air and flit and float until they cover the world with that blanket of white. I love to catch snowflakes and quickly inspect them to see if I can distinguish each different design before they melt from the heat of my outstretched, gloved hand.
There's no doubt about it. While some folks despise winter, I find solace in it. I find peace. I find tranquility.
Yes, I think you can find serenity in a season. And for me, it's winter. Slowing down and hibernating a bit when the air turns cold brings a sense of peace. A snowfall can turn a noisy, bustling day into one of quiet and solitude, temporarily bringing the craziness of life to a halt.
Curled up under a fleecy throw with a hot cup of tea in the silence of an empty nest watching the world outside my window turn a fresh, clean white provides serenity.
So can taking a peaceful walk on a snowy winter afternoon or evening, whether it's here at my country home, down a wooded path, or even in a suburban neighborhood.
Serenity is where you find it. I find it in prayer. I find it in silence. I find it even in the dead of winter.
What about you? Where do you find serenity? Is it a real place or just a state of mind?
"Winter, a lingering season, is a time to gather golden moments, embark upon a sentimental journey, and enjoy every idle hour." ~ John Boswell
©2015 mamasemptynest.wordpress.com
Wordless Wednesday: stuck in the middle
Just keepin' it real
Life. Sometimes it gets in the way of our plans.
If you're a steady reader of Mama's Empty Nest, you may have noticed I've been on a writing hiatus for the last couple of weeks. The evidence is a lack of written posts with only two Wordless Wednesdays showcasing a couple of my photographs instead.
The hiatus wasn't intentional. I didn't just decide to take a break from blogging. No, instead life happened. Real life sometimes gets in the way of blogging life. And you might just say, today I'm keeping it real.
As soon as this new year of blank pages arrived, my calendar started filling up with events and appointments and lists of things needing accomplishment the way life demands and…well, you get the picture.
Both weeks found me trotting off to school as I was scheduled to substitute teach two and a half days one week and two days the following week. One week I taught middle schoolers everything from language arts to science and the next I subbed in learning support and worked non-stop with students from kindergarten through fifth grade in reading and math.
But wait! Just like the infomercials on TV, that's not all! Bible study resumed, so a lot of reading ensued and thought-provoking questions needed answering. Several meetings also required my attendance and church activities increased because in a weak moment, I said yes. Not just to one new obligation but two!
I agreed to become a committee member for a church commission responsible for education of our children, teens, and adults and then because one of the Sunday School classes desperately needed a teacher, guess who is now also teaching young teens in 7th and 8th grade? I mean who could turn down that opportunity when one of the young girl students specifically requested me?
So that meant acquiring curriculum, and checking it out thoroughly, preparing lessons, and because there's that teacher side of me that insists a classroom should be just as stimulating as the lesson, I rearranged the dull-looking church room, added some visuals, and made plans to enhance the space more while spending way too much time on Pinterest looking for additional ideas.
In between all of that, home chores to accomplish, phone calls to return, friends to check on due to illnesses or just because they were going through a tough time, prayer chain requests to lift up to the Lord, and to be honest, a little worrying done over the safety of my world travelers (who, by the way, finally returned home safely from their three-week grand African adventure), and concern for the health of my pregnant daughter also grabbed my attention.
When it came to carving out time to sit down and write for my blog, I thought that either: a. I didn't have time or b. I was just too weary/distracted/unmotivated to think coherently let alone write a decent sentence. If I did snag a little block of time and sit down at the computer, I found myself just vegging out by scrolling through Facebook to see what I may have missed in the lives of friends and family instead of writing a blog post. Yeah, I know….not a productive use of my time…but mindless which is what I needed I guess.
And that's where I ran across this little gem. If you're addicted to social media in any way, you may find yourself taking these inane quizzes that pop up on your newsfeed. You know the ones. What flower are you? Or what kind of house are you? Or what country are you?
I usually pass by those but every once in a while I fall prey to one and succumb to taking the quiz. I admit they are pretty ridiculous and random and I'm fairly certain the answers you get are random as well. But occasionally, the results of one of those idiotic quizzes makes me think "Hmmm, that kind of does describe me."
I know. Silly.
If you've read much of my writing, there is one thing I do think that stands out. I do try to be genuine. I attempt to be frank and authentic in my writing and I'll use that buzz word that seemed to be making the rounds for a while – transparent.
In other words, I try to keep it real.
Well, wouldn't you know it? During this 'off' time away from writing blog posts, I answered one of those Facebook quizzes named "What four-letter word best describes you?" (That sounds a little risky, doesn't it?) The resulting four-letter word could have been any one of these: hope, calm, kind, love, or real.
And this is what I got: "REAL. You are a very sincere and honest human being. You're very much in line with your values, and you always try to be a better person for yourself and for others. As a person with integrity, you are principled and you keep it real like no other. You don't just talk the talk, you actually walk the walk every single day."
While I'm not totally convinced that description really does fit me, as a believer in Jesus I do strive to be the kind of person described in the above paragraph. So, I could explain my blogging world absence by saying I was taking time to concentrate on so many other areas of my life or that I was just so preoccupied with activities and events, I just couldn't find time to write.
But you know what? I'm keepin' it real. The truth is that my life is no busier than yours is. And I'm certainly not perfect, nor do I lead a perfect life or keep a perfectly clean, tidy house. The trash can is overflowing, dirty dishes are piled up in the sink that also needs a thorough scrubbing, and the carpet needs vacuumed. That's reality.
But the truth is sometimes I just don't feel like doing it all.
So why didn't I write anything during the last few weeks? Here's the truth. I just didn't feel like it. And that's keepin' it real.
"The real things haven't changed. It is still best to be honest and truthful; to make the most of what we have; to be happy with simple pleasures; and have courage when things go wrong." ― Laura Ingalls Wilder
©2015 mamasemptynest.wordpress.com
Wordless Wednesday: backyard visitor
Wordless Wednesday: yep, it's January
Climb every mountain
Okay, it's confession time. Mama's not a big risk taker. I like a little adventure for sure, but I usually play it safe. It's true that Papa is a little bit more daring than me, but I still truly wonder from where our adult children inherited their 'adventure genes.'
All three of them have traveled to other countries outside of our own. I have only been to Canada a couple of times, although Papa promises we will expand our horizons when he retires. All three of them have successfully and willingly jumped out of an airplane to sky dive. I'm definitely not planning that anytime soon. There have been episodes of helicopter piloting and waterfall rappelling. Um…no, not for me.
Mama seldom takes the path less traveled because she doesn't want to get lost. Give me a map and I'll be fine but don't set me adrift without directions. But more than that, Mama just doesn't have that sense of adventure. Papa can't even get me on a cruise ship. Airplanes are fine but the thought of being on a ship out in the middle of the ocean sets my heart to racing and gives me visions of panic attacks.
So adventurous living might not be my forte but I do admire those who dare to be bold. That's probably why I hate to miss any episodes of TV's Amazing Race. And I enjoy exciting ventures vicariously through my own offspring as well.
Some of you may remember that my oldest daughter and son-in-law are on a grand adventure right now. They flew to Tanzania in Africa via Amsterdam (with a short sightseeing tour there) to climb Mount Kilimanjaro.
Prior to their trip, I knew some basic facts about this mountain. I knew it's located in Africa and is the tallest free-standing (not part of a mountain range) mountain in the world at an elevation of over 19,300-some feet. I also knew that it would take several days of hiking to reach the summit.
Now, this Mama has been to the mountains. I've even hiked a little in some of them. But the highest elevation I've ever been (not counting airline flights) occurred when Papa and I took a vacation to western Colorado's San Juan Mountains way back when we were young whippersnappers.
We drove from the flat prairieland of Oklahoma to places where the altitude gave me headaches. Little did I know then that headaches are a symptom of altitude sickness. We traveled by railroad from Durango to Silverton (9, 305 feet), by car to Ouray and crossed Wolf Creek Pass (altitude 10,857 feet), one of the high mountain passes on the Continental Divide.
I've been on other mountains in the Pacific Northwest like Mount Hood and Mount St. Helens, to Mount Shasta in northern California, through the Appalachian Mountains here in the east and recently to the top of Mount Mitchell in North Carolina (altitude 6,683), the highest point east of the Mississippi River.
But I've never trekked up a mountain on foot like my loved ones are doing. I'm extremely happy and relieved to say that they reached the Uhuru Peak on Kilimanjaro sometime early yesterday morning (our time) and after an arduous climb to the top, they began their descent down the mountain.
My 'kids' assured me that the trek up the mountain wasn't technical mountain climbing, more like hiking several hours a day for a week through different ecological zones starting in a tropical jungle and going through the savannah and the desert, entering forests, and finally reaching the alpine zone above the timberline. Click here to watch a video to see what a trek up Kilimanjaro is like.
Well, I'm glad that I didn't google information about this trip before they actually left as it would have made me worry even more than I did about their safety. I mean this mountain is named Kilimanjaro (does anyone besides me hear that 'kill a man' part in there?
But seriously, I read daunting facts like these from National Geographic just yesterday that gave me a little pause for alarm: the overall average successful ascents to the peak is 45% out of the approximate 35,000 climbers who attempt the trek yearly. And that there are an estimated 10-15 deaths annually because of severe altitude sickness, hypothermia, falls or other medical issues. And that my loved ones would have a difficult scramble over something called the Barranco Wall (click on that for another video).
Or that even though it takes the average person a minimum of between six to nine days to reach Kilimanjaro's summit, the real challenge is how altitude affects the body and the incidence of acute mountain sickness is high – a possible 75% of trekkers suffer from it on summit night.
I received a text from son-in-law last Friday that informed us that they had been up to 17,000 feet that day and were camping at 13,000 feet. So far the weather had been, in his words, "absolutely incredible." But as they faced the Barranco Wall the next day, he asked us to pray for our daughter who had a slight headache and loss of appetite (some symptoms of altitude sickness).
Just like her mother, I thought, and then I promptly asked everyone I knew to start praying for her. Other than feeling occasionally a bit breathless, our son-in-law reported he was fine and their friend traveling with them was also doing well.
We waited on pins and needles (and that was before I googled information or watched these videos) to hear from them again. Yesterday early in the morning around 2:15, my phone awakened me with a text, again from son-in-law. They had reached the summit which was "incredibly hard, especially coming back down." They still had three more hours to hike to get to the campsite from there and I spent much time in prayer for them.
On one hand, I was relieved but on the other hand, I definitely stayed on prayer alert until they got down off that mountain. I'm grateful that they experienced a mountaintop adventure and achieved such a lofty goal. From there, they will go on a safari in the Serengeti National Park and do more touring around Tanzania before they fly back to Amsterdam, where they will sightsee once more, before finally arriving back home.
For oldest daughter and son-in-law, this grand adventure in life is a dream trip. As the words to "Climb Every Mountain" from the musical The Sound of Music run through my mind, I can't wait to hear all about this mountain dream of theirs that became reality.
"Adventure is not outside man; it is within." ~ George Eliot
©2015 mamasemptynest.wordpress.com
A brand new page
It's here. It says so right here on my brand new calendar. The one with empty spaces for each new day in this new year of 2015. Two thousand and fifteen. Two thousand and fifteen!
Wasn't it just yesterday that the entire world worried their gigabytes off because the page was turning over to the year 2000 and all of those 'experts' predicted a major catastrophe as we reached Y2K? Y2K, the year 2000.
Well, of course the year 2000 arrived and passed by without a glitch. And here we are 15 years later welcoming in another new year. It's true what my wise Daddy used to say that the older you became the faster the years flew by. And we've just put another year on the back shelf.
What lies ahead is anyone's guess but I know one thing. We will fill up those empty spaces on the calendar with the everyday task of living if the Lord gives us a year full of new days. But just living is not how I want to spend these blank spaced days on my calendar of life.
I want to fill those days with wonder. With joy. With love. With exuberance. With amazement. With opportunity. With thanksgiving (yes, I haven't given up that word yet).
In years past, I either chose or was given a new word for each year – a word that might manifest itself in some way to prove amazing or noteworthy as it worked its way through the pages of my life. Sometimes I struggled with those words – the ones like peace, strength, growth.
This year, I haven't chosen a word nor has one come across the crowded desk of my mind for me to take notice. Out of the thousands and thousands of words in my native English language, I haven't claimed one for my own. And not a word has settled upon me and laid claim to me either.
Instead perhaps I should choose a different word for each day of the new year. After all, a new year – one that's sparkling clean with no dings or dents, no marks or notations, no regrets or regressions – presents itself for new ideas, new revelations, new…everything.
I'm not one for making resolutions every year. I usually fail miserably at them, so I stopped torturing myself years ago. But even though I don't make resolutions, I do have resolve. And though my slate is empty right now and my calendar is clear for the time being, I know there's one thing I plan to muster up enough resolve to do this year.
I will take each fresh new day as it comes and see what the Lord will show me on that day because even when I can't be completely faithful, God is. Morning by morning, new mercies I'll see.
"Because of the Lord's great love we are not consumed, for his compassions never fail. They are new every morning; great is your faithfulness. I say to myself, "The Lord is my portion; therefore I will wait for him." ~ Lamentations 3:22-24 (NIV)
What about you? How will you fill your new calendar in this brand new year?
"Every time you tear a leaf off a calendar, you present a new place for new ideas and progress." ~ Charles Kettering
©2015 mamasemptynest.wordpress.com
Words Full Wednesday: New Year's Eve
Wednesdays are usually my no words day here at Mama's Empty Nest. Usually I post a photograph I've taken that hopefully speaks for itself, slap a title on it that categorizes it, and add no other words. Voila! Wordless Wednesday.
But today I'm deviating from the norm. It is, after all, the last day of the year. We say goodbye to 2014 at midnight and hello to brand new 2015 at 12:01.
And today I find on this last Wednesday of the year that I do have words to convey. So this middle of the week post will be a 'words full Wednesday.'
The graphic I designed above boasts a citation that is in my well-worn quote notebook. Supposedly, it came from one of the works of Greek playwright Euripedes. Many moons ago, I took a classical literature class in college where we read many of the Greek classics. I didn't remember the quote at all or where it came from, so I wanted to do a bit of research to see if it even came from Euripedes' pen.
As near as I can glean from a quick research scan (and I do mean quick), the actual quote is "Waste not fresh tears over old griefs." Some of the old Greek's tragedies were lost or only fragments remain. Apparently, this line came from one of those.
No matter the source, the line speaks well for today of all days – New Year's Eve. Another year has passed which included some wondrous occurrences and some disappointing or devastating ones. Such is life.
I spent a good part of this past year grieving over an old wound from 2013. Yes, I wasted fresh tears over it. Sometimes it haunted my dreams; often it consumed my joy during daytime hours. Some days it just fired my anger into a red hot flame.
But you know what? No more. Was what was done to me right? By no means. It was unjust and no mercy or grace was shown. But I refuse to let that grievous event define me any more. I will not waste tears over old griefs any longer. I've learned to put that wrong and the people involved behind me. That doesn't mean I haven't forgiven them because I have, it just means I will no longer allow those circumstances to reign over my emotions and thoughts.
As I move forward to a new year of opportunity, I will not waste one more minute over this old grief. It will stay in the past where it belongs.
What about you? Is there something from the past that you need to let go with the ringing in of a new year? I pray you find the courage to do so and waste not your own tears over past griefs. Let's greet the new year with joy instead of sorrow, with excitement instead of disappointment, with opportunity instead of regrets.
Happy New Year!
"Drop the last year into the silent limbo of the past. Let it go, for it was imperfect, and thank God that it can go." – Brooks Atkinson
©2014 mamasemptynest.wordpress.com


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Poison Ivy
last updated:
Fri, 5/17/2013 3:38 PM
School is almost out and for most kids the summer will be full of outdoor activities. Hikes, camping trips and simple outdoor play will be at the top of many lists. To avoid contact and a reaction from poison ivy, parents should teach their kids what it looks like and also what it does. We talked to Dr. Christie Michael, an allergist at Le Bonheur Children's Hospital to learn more. Here's what she had to say:
"Not everyone reacts to poison ivy. However, just because a reaction didn't occur in the past doesn't mean it won't in the future. Prevention is best so kids should learn what the leaves look like. If your child is exposed, bathe him or her immediately and add 3/4 cup of bleach to a tub of bath water. Once lesions develop, use topical benadryl or steroid cream such as cortisone. Avoid scratching but if itching is severe, an oral antihistamine can be given. For bad reactions, visit your pediatrician who might prescribe a short course of oral steroids."
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Are these weeds or flowers??
mbod1982July 31, 2014
Are these weeds or actual flowers? They are growing around my tree, among balloon flowers. the first one is about 3' tall, and the second is almost 6' I don't know if they were perennials I planted last year or something I Need to get rid of
Sorry the photos are blurry, it's pretty windy out.


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Book your room at Park Hotel
Double RoomMax Occupancy: 2 guests (up to 1 child)
Single RoomMax Occupancy: 1 guest
Triple RoomMax Occupancy: 3 guests (up to 2 children)
Quadruple RoomMax Occupancy: 4 guests (up to 3 children)
Hotel in London (Victoria) near Victoria Palace Theatre
This hotel is located in London (Victoria), close to Westminster Cathedral, Victoria Palace Theatre, and Tate Britain. Also nearby are Buckingham Palace and Big Ben.
Hotel Features
Amenities at Park Hotel include wireless Internet access (surcharge) and a 24-hour front desk.
Room Amenities
In addition to wireless Internet access (surcharge) and coffee/tea makers, guestrooms feature desks along with hair dryers and televisions.Information missing or incorrect? Tell us!
Hotel Amenities
Hotel Amenities
Guests can enjoy a complimentary breakfast. High-speed wireless Internet access is available for a surcharge.
- 24-hour front desk
- Total number of rooms - 18
- Number of floors - 4
- Free breakfast
- Elevator/lift
- WiFi (surcharge)
Available in all rooms: WiFi (surcharge)
Available in some public areas: WiFi (surcharge)
Room Amenities
- Coffee/tea maker
- Hair dryer
- Television
- Desk
- Iron/ironing board (on request)
- WiFi (surcharge)
Where to Eat
Guests are offered a complimentary continental breakfast.
Hotel Policies
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$13,999 HSS19 Honey Swim SpaPools, Spas & Hot Tubs · Reading, PAHoney Spas custom builds all of our Swim Spas to meet our customers needs and budget. A honey swim spa is excellent for aquatic exercise ...Ellyn H. · 13 hours ago
$200 Fine China - Service for 8 -Everything Else · Wescosville, PAJUST REDUCED FROM $250 TO $200. Fine China Set plus serving dishes - platium wheat design. Brand new - never used. Original cost over $45...Janet B. · 1 day ago
$15 Krystonia-Twingnuk #506Arts & Crafts · Stowe, PATwingnuk-# 506 This troll has a name but no one (including himself) remembers it. He goes by the nickname Twingnuk. I venture to guess th...Chester M. ·7 listings · 1 day ago
$20 Krystonia-Spreading his Wings #501Collectibles · Stowe, PASpreading HIS Wings-#504 An Owhey flight is full of emotions. Fear for who knows how long it will last. Anticipation for where you will ...Chester M. ·7 listings · 1 day ago
$240 New Att Samsung Mega 6.3 white unlocked phoneElectronics · Reading, PAI have for sale several new Att Samsung Mega 6.3 unlocked. This phone will work on any gsm carrier. You get new phone, charger, earbuds, ...Gregory J. · 1 day ago
$35 Krystonia-Oops & Cudha Tree #3907 & #705Collectibles · Stowe, PAOops-#3907 Being the he best does not always insure that you will not run into difficulty. Jumbly the Juggler has found this out. With on...Chester M. ·7 listings · 3 days ago
$12 Krystonia-Owhey #1071Collectibles · Stowe, PAOWHEY #1071 The youngest of the Krystonian dragons finds the good in all. His constant excitement over new and wonderful things often giv...Chester M. ·7 listings · 1 week ago
$380 Adirondack Chairs, Footstools, and TableOther Furniture · Royersford, PACustom Built - Wood Adirondack Chairs, Footstools, and Table Finished with KILZ Primer and Exterior Deck Paint - Sturdy ConstructionBrian N. · 1 week ago
$2 Boy's Winter Pj'sKid's Clothes · Wescosville, PAI have: a Disney Toy Story "Buzz Lightyear" Blue bottom pj size 4/5-$3 Disney Grey & Red "Pirates of the Caribbean" bottom pj size XS wi...
$400 automatic medicine machineEverything Else · Pottstown, PAM2 Automatic release medicine machine. It operates on your clock and phone system and talks at the designated times saying "Time to take ...Cindy C. · 1 week ago
$22 Kruystonia-Poffles & Trumph #1401Collectibles · Stowe, PAPoffles #1401 Poffles can be easily located by following the sound of his irrepressible giggles. Nothing makes him and his friend, Trumph,...Chester M. ·7 listings · 1 week ago
$20 Soccer Teddy Bedroom LightBaby & Kid Stuff · Allentown, PAThis cute Bedroom Lamp is for a child who likes teddy bears. This teddy bear is holding a soccer ball. It is brand new -in the original box
$5 Milk Glass Plate -Antiques · Wescosville, PA8" decorative milk Glass Plate - $10 -collector's item or entertaining use. In excellent condition. This plate is almost 50 years old and...
$1,495 Resin Farm Animals and FiguresEverything Else · Kutztown, PALots of resin farm animals and statues to chose from! Prices vary depending on the animal you choose! For more information call 484-646...GRQ Used Furniture · 1 week ago
$15 Krystonia-Turfen #1601Collectibles · Stowe, PATurfen-#1601 (L) Turfen's work begin as night falls. Weaving moonlight through a krystal, he sends out spells that bring deep-resting and...Chester M. ·7 listings · 2 weeks ago
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The White King's Rook
Artist: LilyM
Biography: Danny
The King's Flank are guarded by a an ancient stone giant (Titan) that was summoned from sleep by the Scholars and practitioners of the University of the Gear.
Over the years and with collaboration with the ancient rites, structures were able to be built upon the titan and secret instructions whispered through its thoughts to protect the King should the occasion arise.
Tee also available
I remember the first WIP of this beast, and my initial thoughts were 'holy crap!' The finished product did NOT disappoint!
This gives castling new meaning… and you didn't even show its teeth. Mighty fine work.
Yes, a fine piece, but it was what the other members did with this piece that will make everyone really appreciate Lily's character.
Truly epic. Right up there in my favourites, along with the Black King Rook
This is really cool
I have to admit, I wasn't expecting anything like this from Lily when she came on board. It just blew my mind : )
Very cool indeed!
Thanks everyone! :D
My personal favourite!
Beautiful work!
Thanks for the kind words!
– GameOfKings


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Despite there being a power cut when we arrived, cooking went on as normal. We had a lovely pizza sitting outside on a patio lit with oil lamps.
hi we ate here last year as well the pizza is very good the atmosphere very nice and the service is very very good they go out of the way to make you feel at home part of our trip is to have pizza here
We were on holiday from Cape Town and felt like some pizza. The resturant is very cosy and we sat outside as it was a lovely evening. The service was good and the staff were friendly. Myself and the kids had pizza while the wife had pasta. The pizzas were very tasty , full of flavour and hot. The pasta...
Had lovely fresh handmade pasta and pizza at this quaint and authentic little Italian restaurant in the centre of Montagu. Good food lovingly made fresh. Friendly service. Cosy Italian vibe with nice decor and music (especially liked the soundtrack of The Mission). Excellent value for money - our bill came in at R270 for a beautiful pizza with 4 toppings,...
This restaurant is very quaint, and inviting. Looking like it stepped out of Italy, it makes for a very pleasant night out. Friendly staff and relaxed atmosphere.
fantastic pizza! The piccolo salad is excellent! The service is good and Quick! We spent a very Nice moment there! We REALLY enjoy the atmosphère there, Nice music! We will come back!
The walls were covered with everything Italian. Some of the older pics were real classic ones. One almost felt we could walk out there into the streets of Florence.
Our pizza was really tasty and the service was good. We will be back for sure!
Stopped in for a meal and were pleasantly surprised to have great thin based crispy fresh pizzas and good coffee along with some decadent cakes for dessert. The staff were pleasant and helpful. When back in Montagu we will stop in again.
When we arrived, our party of 11 was the only table in the restaurant. We initially sat inside, but later, due to it being unseasonably pleasant outside, we enquired if we could join two of the outside tables together and sit there, to which the reply, from the manager, was: "The owner doesn't allow it". Having been associated with the...
Rude people as when you get there they are closed but the sign says the opening times but all they tell you is that it is wrong and you must come back at 6, they won`t even say come and sit and enjoy a drink at the bar until they open. Will not go back there.
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Chippewa Falls notches first win ever over SHS hockey team
The Superior High School boys hockey team fell to 1-4 on the season with an 8-4 loss at Chippewa Falls Thursday night at the Chippewa Area Ice Arena.
The win was the first ever for the Cardinals over the Spartans, who went into the game leading the all-time series 10-0.
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Embedded: "Real men(and women) program in C"
- Login or register to post comments
- by voodoobot
By voodoobot
August 10, 2009
August 10, 2009
A great link on the use of c in the embedded technology world.
By da_cobra @ Sun, 2010-05-02 12:56
Uhm, maybe I'm missing
Uhm, maybe I'm missing something, but where is the read?
By rik @ Sun, 2010-05-02 18:40
It's in "A great link"
A great link
Click the great link
Because it's the great link that contains the read.
By TeleFox @ Tue, 2009-08-11 00:09
An interesting read, cheers
An interesting read, cheers voodoo.


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AD Tag – GNN
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Interview: Todd Lincoln - Director (V/H/S: Viral, The Apparition, Gorgeous Vortex)March 26th, 2015Interviewed by: Todd Martin
Exclusive Interview: Michael Berryman - Wednesday, March 25th at 9pm ESTMarch 23rd, 2015Interviewed by: Mike Joy
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Book Review: The Pendle Curse - Author Catherine CavendishReviewed by: Dave Gammon
Book Review: Mutations - Authors E.L. Loraine and Tim FrasierReviewed by: Todd Martin
Film Review: The Killer Shrews (1959)
SYNOPSIS: "Boat Captain Thorne Sherman and his black sidekick, Rook Griswold, arrive to deliver supplies to a remote and isolated island, inhabited by a scientist, his daughter and his aides. Sherman soon learns that the scientist and company have created out-of-control, flesh-eating, monstrous giant shrews. A hurricane hits and all the stranded humans become either meals for or meal-targets for the shrews." (courtesy IMDB) REVIEW: As the fifties drew to a close so did the … Continue reading


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The Graduate Center offers more than thirty doctoral programs in the arts, humanities, social sciences, and natural sciences, including History.
Learn about the Graduate Center's core faculty,
including Distinguished Professor David Joselit (pictured),
on the Faculty Profiles page.
Through its extensive public programming, the Graduate Center contributes to the intellectual and cultural vitality of New York City.
The Graduate Center has announced its
Doctoral Student Parental Accommodation Policies.
Support for the Graduate Center ensures continued excellence in arts and
sciences graduate education, research, and public programming.
Attention Students and Graduates:
As of February 17th, email will no longer be received in your existing GC email account. All email, including official communication from the GC, will be... Read more
Attention GC Community,
Please be aware that recently we have seen phishing attempts increasing both in sophistication and frequency, often mimicking legitimate Graduate Center resources in clever... Read more
The FBI Internet Crime Center reports that university employees across the country are receiving fraudulent e-mails indicating a change in their human resource status so perpetrators can steal employee credentials and access direct deposit accounts. This alert outlines precautions that should be taken to protect yourself from this type of crime.
Read more
Attention Graduates:
Now Live!
To begin using your new Office 365 email account, please go to the address below and enter the credentials that were provided to you via your GC email... Read more
Attention Graduate Center Students:
To begin using your new Office 365 email account, please go to the address below and enter the credentials that were provided to you via your GC email... Read more
If you are a Mac user and have received this error message when attempting to login to the GC's remote computing service (http://remote.gc.cuny.edu):
"You have not chosen to trust... Read more
As of September 3, 2013 IT is relinquishing the bookings for the IT Computer Classrooms (C196.01, C196.02, C196.03, C415B and 6418) to Room Reservations. Requests for these spaces should be... Read more
On Monday, 4/15/13 two bombs exploded near the finish line of the Boston Marathon, killing three people and injuring more than 140. The FBI and Boston Police Department are investigating various leads but as of now it is still unclear who might be responsible for the blast. NYPD Police Commissioner Raymond Kelly announced this morning that while there is no known threat to New York City, NYPD is on heightened alert and is increasing its uniformed presence and taking other special precautions. In addition, the Office of Security & Public Safety will step up perimeter patrols, paying special attention to parked vehicles and unattended packages.
Read more
Recently there has been an increase in bicycle part thefts from the streets around our building. Wheels and seats from expensive bicycles are particularly attractive targets but any unsecured bike part is at risk. A recent inspection of bicycles parked in front of our building revealed that many were vulnerable to theft. Read more
The personal safety of students, staff, faculty and visitors is of primary importance at the Graduate Center. In the wake of the school shooting at Newtown, Connecticut, we are once again reviewing our present security posture and emergency operation plans and will be looking at strategies to prevent such incidents from happening on our campus.


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Monday, January 1, 2007
Kickass Intro To Quicksilver Video
If you read about it, you might wonder wtf the point is. Watch this video and you'll understand right away.
Posted by Giles Bowkett at 10:20 AM
Labels: design, os x, quicksilver
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As part of our "How I Shot That" series, we asked a selection of cinematographers with films at Sundance what the best film school for cinematographers is -- and whether they think cinematographers need to go to film school at all. Here's a selection of their answers.Read More »
Here's your daily dose of an indie film in progress; at the end of the week, you'll have the chance to vote for your favorite.Read More »
Christmas parties wouldn't exist without the countless lights used for decoration, which made for an interesting experience for cinematographer Ben Richardson, who most recently went to Sundance with the Oscar-nominated "Beasts of the Southern Wild" and now returns with Joe Swanberg's Anna Kendrick-...Read More »
Rachel Beth Anderson, cinematographer of "E-Team," which is a documentary playing at the 2014 Sundance Film Festival, discusses with us her experience shooting the film. "E-Team," directed by Katy Chevigny and Ross Kauffman, follows a group of individuals selected by the Human Rights Watch to docume...Read More »
After shooting a bunch of short films and music videos, cinematographer Shachar Langlev debuted his first feature-length film,"Alive Inside: A Story of Music & Memory" at the 2014 Sundance Film Festival. The documentary, directed by Michael Rossato-Bennett (also a first timer), looks at a powerful e...Read More »
"Wish I Was Here" sold big at The Sundance Film Festival. How do his Kickstarter backers feel about the film's success?Read More »
Here's what cinematographers with films at Sundance 2014 think of shooting film vs. digital.Read More »
Cinematographer Alex Disenhof spoke to Indiewire about shooting "Fishing Without Nets," a U.S. Dramatic entry that premiered at the 2014 Sundance Film Festival and was directed by Cutter Hodierne.Read More »
Here's your daily dose of an indie film in progress; at the end of the week, you'll have the chance to vote for your favorite.Read More »
Cinematographer John Guleserian recently worked on "Like Crazy," "Breathe In," and "About Time." "Song One" is Kate Barker-Froyland's melodic drama starring Anne Hathaway and Mary Steenburgen.Read More »


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This Week in TWiT Dec. 3, 2011
Posted by Bryan December 4, 2011
Leo Leporte and Lisa Kentzell talk with the chatroom about the state of TWiT.
Topics: Guest Stephen Collins Product Manager at BitTorrent, a how to show (maybe), what cars TWiT employes drive, Leo packing for Paris, crazy December weather in Petaluma and none of your calls.
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Are you David A Barrett?Claim your profile
Publications (162)689.89 Total impact
Article: A strategy for characterization of triterpene saponins in Caulophyllum robustum hairy roots by liquid chromatography with electrospray ionization quadrupole time-of-flight mass spectrometry[Show abstract] [Hide abstract]
ABSTRACT: Triterpene saponins are important bioactive constituents widely distributed in many plants. Saponins present in Caulophyllum (Berberidaceae) have not been fully characterized. In this study, we studied triterpene saponins from Caulophyllum robustum using liquid chromatography combined with electrospray ionization quadrupole time-of-flight mass spectrometry (LC-qTOF-MS). Rapid identification of Caulophyllum saponins was facilitated using low and high MS cone voltages to induce controlled fragmentation in positive mode. The full scan spectra at low cone voltage of 40V provided considerable structural information relating to aglycone skeletons, sugar types, and linked sequences for Caulophyllum saponins. Seven Caulophyllum aglycones were differentiated and identified by their diagnostic fragment ions combined with accurate mass measurements and characteristic fragmentation pathways. Peak intensity ratio of [aglycone+H-2H2O](+) to [aglycone+H-H2O](+) in full scan spectra acquired with low cone voltage is correlated with structural features of hederagenin and echinocystic acid and is useful for the discrimination of these positional isomers. However, at a high voltage of 200V, the saponin [M+H](+) ion and its fragmentation ions were not present; and the single saponin [M+Na](+) generated [Bα+Na](+) and [Y0α+Na](+) by in-source fragmentation, which provided structural information on the α- and β-sugar chains in the saponins. This approach enabled simultaneous acquisition of structural information on both aglycones and sugar chains from full scan spectra in one injection. Based on the developed strategy, 51 triterpene saponins of seven different classes were fully characterized or tentatively identified, of which 32 constituents were the first to be reported in genus Caulophyllum and 18 compounds were characterized as potentially new compounds.Journal of Pharmaceutical and Biomedical Analysis 11/2014; 100:109–122. DOI:10.1016/j.jpba.2014.07.024 · 2.83 Impact Factor
Article: Rapid Detection of Peptide Markers for Authentication Purposes in Raw and Cooked Meat Using Ambient Liquid Extraction Surface Analysis Mass Spectrometry[Show abstract] [Hide abstract]
ABSTRACT: In this paper, our previously developed ambient LESA-MS methodology is implemented to analyze five types of thermally treated meat species, namely beef, pork, horse, chicken, and turkey meat, in order to select and identify heat-stable and species-specific peptide markers. In-solution tryptic digests of cooked meats were deposited onto a polymer surface, followed by LESA-MS analysis and evaluation using multivariate data analysis and tandem electrospray MS. The five types of cooked meat were clearly discriminated using principal component analysis and orthogonal partial least squares discriminant analysis. A number of 23 heat stable peptide markers unique to species and muscle protein were identified following data-dependent tandem LESA-MS analysis. Surface extraction and direct ambient MS analysis of mixtures of cooked meat species was performed for the first time and enabled detection of 10% (w/w) of pork, horse, and turkey meat, and 5% (w/w) of chicken meat in beef, using the developed LESA-MS/MS analysis. The study shows, for the first time, that ambient LESA-MS methodology displays specificity sufficient to be implemented effectively for the analysis of processed and complex peptide digests. The proposed approach is much faster and simpler than other measurement tools for meat speciation; it has potential for application in other areas of meat science or food production.Analytical Chemistry 09/2014; 86(20):10257-10265. DOI:10.1021/ac502449w · 5.83 Impact Factor
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ABSTRACT: Polycystic ovary syndrome (PCOS) is a common disorder affecting between 5 and 18 % of females of reproductive age and can be diagnosed based on a combination of clinical, ultrasound and biochemical features, none of which on its own is diagnostic. A lipidomic approach using liquid chromatography coupled with accurate mass high-resolution mass-spectrometry (LC-HRMS) was used to investigate if there were any differences in plasma lipidomic profiles in women with PCOS compared with control women at different stages of menstrual cycle. Plasma samples from 40 women with PCOS and 40 controls aged between 18 and 40 years were analysed in combination with multivariate statistical analyses. Multivariate data analysis (LASSO regression and OPLS-DA) of the sample lipidomics datasets showed a weak prediction model for PCOS versus control samples from the follicular and mid-cycle phases of the menstrual cycle, but a stronger model (specificity 85 % and sensitivity 95 %) for PCOS versus the luteal phase menstrual cycle controls. The PCOS vs luteal phase model showed increased levels of plasma triglycerides and sphingomyelins and decreased levels of lysophosphatidylcholines and phosphatidylethanolamines in PCOS women compared with controls. Lipid biomarkers of PCOS were tentatively identified which may be useful in distinguishing PCOS from controls especially when performed during the menstrual cycle luteal phase.Metabolomics 08/2014; DOI:10.1007/s11306-014-0726-y · 3.97 Impact Factor
Article: A Translational Insight into Statin-Induced Muscle Toxicity: from Cell Culture to Clinical Studies[Show abstract] [Hide abstract]
ABSTRACT: Statins are lipid-lowering drugs widely used for prevention and treatment of cardiovascular and coronary heart diseases. These drugs are among the most commonly prescribed medicines intended for long term use. Statins are generally well tolerated. However, muscular adverse effects appear to be the most common obstacle that limits their use, resulting in poor patient compliance or even drug discontinuation. In addition, rare but potentially fatal cases of rhabdomyolysis have been reported with the use of these drugs, especially in the presence of certain risk factors. Previous reports have investigated statin-induced myotoxicity in vivo and in vitro using a number of cell lines, muscle tissues and laboratory animals, in addition to randomized clinical trials, observational studies and case reports. None of them have directly compared results from laboratory investigations with clinical observations of statin related muscular adverse effects. To the best of our knowledge this is the first review article that combines laboratory investigation with clinical aspects of statin-induced myotoxicity. By reviewing published literature of in vivo, in vitro and clinically relevant studies of statin myotoxicity, we aim at translating this important drug related problem in order to establish a clear picture of proposed mechanisms, to explain the risk factors and describe the diagnostic approaches currently employed for evaluating the degree of muscle damage induced by these agents. This review provides a baseline novel translational insight that can be used to enhance safety profile, minimize the chance of progression of these adverse effects to more severe and potentially fatal rhabdomyolysis and improve the overall patient compliance and adherence to long-term statin therapy.08/2014; DOI:10.1016/j.trsl.2014.01.013
Article: Simultaneous tissue profiling of eicosanoid and endocannabinoid lipid families in a rat model of osteoarthritis[Show abstract] [Hide abstract]
ABSTRACT: We describe a novel liquid chromatography method for the simultaneous and quantitative profiling of forty-three oxylipins including eicosanoids, endocannabinoids and structurally-related bioactive lipids with modified acyl groups. The LC-MS/MS method uses switching at a defined time between negative and positive electrospray ionisation modes to achieve optimal detection sensitivity for all the lipids. The validated method is linear over a range 0.01 - 5 nmol/g (0.1 to 50 nmol/g for 2-arachidonoyl glycerol) with intra- and inter-day precision and accuracy was between 1.38 and 26.76% and 85.22 and 114.3% respectively. The method successfully quantified bioactive lipids in different tissue types in the rat, including spinal cord, dorsal root ganglia), knee joint, brain and plasma. Distinct regional differences in the pattern of lipid measured between tissue types were observed using principle component analysis (PCA). The method was applied to analyse tissue samples from an established pre-clinical rat model of osteoarthritis (OA) pain and showed that levels of 12-hydroxyeicosatetraenoic acid were significantly increased in the OA rat knee joint, compared to controls and that 15- hydroxyeicosatetraenoic acids was significantly increased in the dorsal root ganglia in model of osteoarthritis, compared to controls. The developed LC-MS/MS method has potential to provide detailed pathway profiling in tissues and biofluids where the disruption of bioactive oxylipins may be involved in disease states.The Journal of Lipid Research 07/2014; 55(9). DOI:10.1194/jlr.M048694 · 4.73 Impact Factor
Article: Folic acid handling by the human gut: implications for food fortification and supplementation123[Show abstract] [Hide abstract]
ABSTRACT: Current thinking, which is based mainly on rodent studies, is that physiologic doses of folic acid (pterylmonoglutamic acid), such as dietary vitamin folates, are biotransformed in the intestinal mucosa and transferred to the portal vein as the natural circulating plasma folate, 5-methyltetrahydrofolic acid (5-MTHF) before entering the liver and the wider systemic blood supply.OBJECTIVE: We tested the assumption that, in humans, folic acid is biotransformed (reduced and methylated) to 5-MTHF in the intestinal mucosa.DESIGN: We conducted a crossover study in which we sampled portal and peripheral veins for labeled folate concentrations after oral ingestion with physiologic doses of stable-isotope-labeled folic acid or the reduced folate 5-formyltetrahydrofolic acid (5-FormylTHF) in 6 subjects with a transjugular intrahepatic porto systemic shunt (TIPSS) in situ. The TIPSS allowed blood samples to be taken from the portal vein.RESULTS: Fifteen minutes after a dose of folic acid, 80 ± 12% of labeled folate in the hepatic portal vein was unmodified folic acid. In contrast, after a dose of labeled 5-FormylTHF, only 4 ± 18% of labeled folate in the portal vein was unmodified 5-FormylTHF, and the rest had been converted to 5-MTHF after 15 min (postdose).Conclusions: The human gut appears to have a very efficient capacity to convert reduced dietary folates to 5-MTHF but limited ability to reduce folic acid. Therefore, large amounts of unmodified folic acid in the portal vein are probably attributable to an extremely limited mucosal cell dihydrofolate reductase (DHFR) capacity that is necessary to produce tetrahydrofolic acid before sequential methylation to 5-MTHF. This process would suggest that humans are reliant on the liver for folic acid reduction even though it has a low and highly variable DHFR activity. Therefore, chronic liver exposure to folic acid in humans may induce saturation, which would possibly explain reports of systemic circulation of unmetabolized folic acid. This trial was registered at clinicaltrials.gov as NCT02135393.American Journal of Clinical Nutrition 06/2014; 100(2). DOI:10.3945/ajcn.113.080507 · 6.92 Impact FactorThis article is viewable in ResearchGate's enriched formatRG Format enables you to read in context with side-by-side figures, citations, and feedback from experts in your field.
[Show abstract] [Hide abstract]
ABSTRACT: Polymeric substrates are being identified that could permit translation of human pluripotent stem cells from laboratory-based research to industrial-scale biomedicine. Well-defined materials are required to allow cell banking and to provide the raw material for reproducible differentiation into lineages for large-scale drug-screening programs and clinical use. Yet more than 1 billion cells for each patient are needed to replace losses during heart attack, multiple sclerosis and diabetes. Producing this number of cells is challenging, and a rethink of the current predominant cell-derived substrates is needed to provide technology that can be scaled to meet the needs of millions of patients a year. In this Review, we consider the role of materials discovery, an emerging area of materials chemistry that is in large part driven by the challenges posed by biologists to materials scientists.Nature Material 05/2014; 13(6):570-9. DOI:10.1038/nmat3972 · 36.43 Impact Factor
Article: Reductions in Endocannabinoid Levels and Enhanced Coupling of Cannabinoid Receptors in the Striatum are Accompanied by Cognitive Impairments in the AβPPswe/PS1ΔE9 Mouse Model of Alzheimer's Disease.[Show abstract] [Hide abstract]
ABSTRACT: Alterations in the endocannabinoid system (ECS) are thought to play a role in learning and memory impairments observed in Alzheimer's disease (AD). We aimed to determine the status of the brain ECS in the AβPPswe/PS1ΔE9 model of AD. The ECS comprises the neuromodulatory lipid endocannabinoids, anandamide and 2-arachidonoyl glycerol (2AG), which interact with the G protein-coupled type-1 and type-2 cannabinoid receptors. Using mass spectrometry, we quantified endocannabinoid levels and assessed lipidomic profiles of the frontal cortex, hippocampus, and striatum of 4-8 month old wildtype and AβPPswe/PS1ΔE9 mice to determine whether regional variations in endocannabinoids and lipid metabolism are observed with age and disease progression. Additionally, open-field activity, performance in the contextual fear conditioning task, and various other tasks assessing spatial and recognition memory were examined to determine the influence of age and pathology on these parameters. At all ages, AβPPswe/PS1ΔE9 mice were significantly hyperactive in the open-field and acquired contextual fear as well as wildtype mice, reflecting intact associative learning. They, however, exhibited enhanced contextual fear memory and reduced contextual fear extinction regardless of age. Disturbances in striatal lipid metabolism were observed in 6 and 8 month old AβPPswe/PS1ΔE9 mice. Endocannabinoids increased significantly with age in the hippocampus and frontal cortex of both genotypes. 8 month old AβPPswe/PS1ΔE9 mice displayed significantly lower levels of striatal 2AG than wildtype mice, but greater cannabinoid receptor/effector coupling. This study shows that alterations in lipid metabolism and endocannabinoid signaling develop with age in AβPPswe/PS1ΔE9 mice, possibly contributing to the development of AD-like behavioral deficits.Journal of Alzheimer's disease: JAD 05/2014; 42(1). DOI:10.3233/JAD-131961 · 3.61 Impact Factor
Article: The use of dicationic ion-pairing compounds to enhance the ambient detection of surface lipids in positive ionization mode using desorption electrospray ionisation mass spectrometry[Show abstract] [Hide abstract]
ABSTRACT: Lipids are typically analysed in negative ionisation mode in desorption electrospray ionisation mass spectrometry (DESI-MS), which can result in reduced sensitivity. In this study we examine the use of dicationic compounds as reactive DESI-MS agents to detect a range of lipid standards from the surface in positive ionisation mode. Nine dicationic compounds were tested for their ability to detect seven representative lipid species (palmitoleic acid, linoleic acid, phosphatidic acid (34:1), phosphoethanolamine (34:2), phosphatidylglycerol (34:1), phosphatidylserine (36:1), and phosphoinositol (34:2)) with a 2D DESI source on hydrophobic surfaces. Two different solvent systems (methanol/chloroform (1:1) and methanol) were tested with each dicationic compound, with the DESI-MS analysis performed in the positive ionisation mode. Most of the dications tested were able to form stable ion-pairs with the negatively charged lipid species when analysed from the surface with DESI-MS, and were detected readily in positive ionisation electrospray mode as singly charged species. The optimal solvent system was found to be methanol. The dicationic compound [C6 (C1 Pyrr)2 ][Br]2 was found to enhance the detection of palmitoleic acid (638%), linoleic acid (304%) and phosphoethanolamine (269%) compared with the negative ionisation mode. We demonstrate the first successful application of dicationic compounds in DESI-MS for the ambient surface detection of model lipids in positive electrospray ionisation mode. Dicationic compounds could potentially be used as reactive DESI-MS agents to improve the ambient detection of a number of negatively charged analytes. © 2014 The Authors. Rapid Communications in Mass Spectrometry published by John Wiley & Sons, Ltd.Rapid Communications in Mass Spectrometry 03/2014; 28(6):616-24. DOI:10.1002/rcm.6826 · 2.51 Impact Factor
Article: Tryptic Digestion Coupled with Ambient Desorption Electrospray Ionization and Liquid Extraction Surface Analysis Mass Spectrometry Enabling Identification of Skeletal Muscle Proteins in Mixtures and Distinguishing between Beef, Pork, Horse, Chicken, and Turkey Meat[Show abstract] [Hide abstract]
ABSTRACT: The use of ambient desorption electrospray ionization (DESI-MS) mass spectrometry and liquid extraction surface analysis mass spectrometry (LESA-MS) is explored for the first time to analyse skeletal muscle proteins obtained from mixture of standard proteins and raw meat. Single proteins and mixtures of up to five proteins (myoglobin, troponin C, actin, BSA, tropomyosin) were deposited onto a polymer surface, followed by in-situ tryptic digestion and comparative analysis using DESI-MS and LESA-MS using tandem electrospray MS. Peptide peaks specific to individual proteins were readily distinguishable with good signal-to-noise ratio in the five-component mixture. LESA-MS gave a more stable analysis and greater sensitivity compared with DESI-MS. Meat tryptic digests were subjected to peptidomics analysis by DESI-MS and LESA-MS. Bovine, horse, pig, chicken and turkey muscle digests were clearly discriminated using multivariate data analysis (MVA) of the peptidomic datasets. The most abundant skeletal muscle proteins were identified and correctly classified according to the species following MS/MS analysis. The study shows, for the first time, that ambient ionization techniques such as DESI-MS and LESA-MS have great potential for species-specific analysis and differentiation of skeletal muscle proteins by direct surface desorption.Analytical Chemistry 03/2014; 86(9). DOI:10.1021/ac5003432 · 5.83 Impact Factor
Article: Fish oil omega-3 fatty acids partially prevent lipid induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation.[Show abstract] [Hide abstract]
ABSTRACT: Acylcarnitine accumulation in skeletal muscle and plasma has been observed in numerous models of mitochondrial lipid overload and insulin resistance. Fish oil omega-3 polyunsaturated fatty acids (n3PUFA) are thought to protect against lipid-induced insulin resistance. The present study tested the hypothesis that addition of n3PUFA to an intravenous lipid emulsion would limit muscle acylcarnitine accumulation and reduce the inhibitory effect of lipid overload on insulin action. On three occasions, six healthy young men underwent a 6-hour euglycaemic hyperinsulinaemic clamp accompanied by intravenous infusion of saline (Control), 10% Intralipid (n6PUFA), or 10% Intralipid + 10% Omegaven (2:1; n3PUFA). The decline in insulin-stimulated whole-body glucose infusion rate, muscle pyruvate dehydrogenase complex activation (PDCa), and glycogen storage associated with n6PUFA compared to Control, was prevented with n3PUFA. Muscle acetyl-CoA accumulation was greater following n6PUFA compared to Control and n3PUFA, suggesting that mitochondrial lipid overload was responsible for the lower insulin action observed. Despite these favourable metabolic effects of n3PUFA, accumulation of total muscle acylcarnitine was not attenuated when compared with n6PUFA. These findings demonstrate that n3PUFA exert beneficial effects on insulin-stimulated skeletal muscle glucose storage and oxidation independently of total acylcarnitine accumulation, which does not always reflect mitochondrial lipid overload.Clinical Science 03/2014; DOI:10.1042/CS20140031 · 5.63 Impact Factor
Dataset: -2014 Rao The use of dicationic ion-pairing compounds to enhance the ambient detection of surface lipids Supplementary
Article: Biosensors for qualitative and semiquantitative analysis of quorum sensing signal molecules.[Show abstract] [Hide abstract]
ABSTRACT: Biosensors are biological tools that can be used to assay bacterial cultures for quorum sensing signal molecules (QSSMs) both qualitatively and semiquantitatively. QSSMs can be extracted from Pseudomonas aeruginosa cultures using organic solvents and tentatively identified via thin layer chromatography in combination with biosensor overlays. Alternatively, QSSMs can be quantified in spent culture supernatants or solvent extracts using biosensor-based spectrophotometric, luminescence, or fluorescence assays.Methods in molecular biology (Clifton, N.J.) 01/2014; 1149:245-54. DOI:10.1007/978-1-4939-0473-0_20 · 1.29 Impact Factor
Article: New Materials for Human Pluripotent Stem Cell Culture: High Throughput Discovery and Prediction of Polymers that Promote Cell Attachment
[Show abstract] [Hide abstract]
ABSTRACT: Extracts taken from spent growth media from Pseudomonas aeruginosa can be analyzed for N-acyl-L-homoserine lactones and 2-alkyl-4-(1H)-quinolones (AQs), including the known quorum sensing signalling molecules of P. aeruginosa, in a specific and sensitive manner by liquid chromatography coupled with tandem mass spectrometric detection. This analysis can be conducted in a quantitative manner by comparison with matrix-matched calibration samples.Methods in molecular biology (Clifton, N.J.) 01/2014; 1149:255-70. DOI:10.1007/978-1-4939-0473-0_21 · 1.29 Impact Factor
Article: Preventing endometrial cancer risk in polycystic ovarian syndrome (PCOS) women: Could Metformin help?[Show abstract] [Hide abstract]
ABSTRACT: Current data indicate that there is a significant risk of endometrial cancer (EC) in women with polycystic ovarian syndrome (PCOS), although further research needed to clarify the exact molecular mechanisms. Endometrial hyperplasia is a premalignant condition that usually heralds EC and it shares identical risk factors with EC. Metabolic syndrome with a triad of obesity, hyperinsulinaemia and diabetes, which, is commonly observed in PCOS appears to be a key mechanism in EC pathogenesis. Measures to improve insulin resistance could therefore play a role in reducing the risk of EC in women with PCOS. Metformin is an insulin sensitizing agent which is safe, widely available and currently licensed for type-2 diabetes. It has been clearly shown in both animal and human studies that metformin is of value in reversing endometrial hyperplasia. Metformin may therefore prevent EC in PCOS. This article reviews the use of metformin in reducing EC risk in PCOS and makes a case for future research on this topic.Gynecologic Oncology 10/2013; DOI:10.1016/j.ygyno.2013.10.028 · 3.69 Impact Factor
Article: Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain.[Show abstract] [Hide abstract]
ABSTRACT: Blockade of transient receptor potential vanilloid 1 (TRPV1) with systemic antagonists attenuates osteoarthritis (OA) pain behaviour in rat models, but on-target-mediated hyperthermia has halted clinical trials. The present study investigated the potential for targeting TRPV1 receptors within the OA joint in order to produce analgesia. The presence of TRPV1 receptors in human synovium was detected using western blotting and immunohistochemistry. In a rat model of OA, joint levels of an endogenous ligand for TRPV1, 12-hydroxy-eicosatetraenoic acid (12-HETE), were quantified using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Effects of peripheral administration of the TRPV1 receptor antagonist JNJ-17203212 on afferent fibre activity, pain behaviour and core body temperature were investigated. Effects of a spinal administration of JNJ-17203212 on dorsal horn neuronal responses were studied. We demonstrate increased TRPV1 immunoreactivity in human OA synovium, confirming the diseased joint as a potential therapeutic target for TRPV1-mediated analgesia. In a model of OA pain, we report increased joint levels of 12-HETE, and the sensitisation of joint afferent neurones to mechanical stimulation of the knee. Local administration of JNJ-17203212 reversed this sensitisation of joint afferents and inhibited pain behaviour (weight-bearing asymmetry), to a comparable extent as systemic JNJ-17203212, in this model of OA pain, but did not alter core body temperature. There was no evidence for increased TRPV1 function in the spinal cord in this model of OA pain. Our data provide a clinical and mechanistic rationale for the future investigation of the therapeutic benefits of intra-articular administration of TRPV1 antagonists for the treatment of OA pain.Annals of the rheumatic diseases 10/2013; DOI:10.1136/annrheumdis-2013-203413 · 9.27 Impact Factor
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Product COM-11102
about 2 years ago
Does anyone know why this is priced the same as the COM-10932? It looks like the COM-10932 is essentially the same thing with a lower resolution. Why would they be priced the same?
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drip irrigation winterizing
Here is my question and thanks in advance for answering.
I installed a drip irrigation line with multiple drip emitters to hit about 80 different plants in our landscape. 1/2 drip line and laterals with 1/4 microtubing and emitters. I installed numerous places for water to be drained at low spots that can simply be opend to drain. However, my question is how to I make sure that the lines that are on level ground will be able to be free of water? I was thinking of compressed air and rigging a connector, but many places on the "net" say NOT to use compreseed air. THe supply line, laterals and micro tubing are all hidden under landscape decoractive rock and I do not want to disturb all that. ANy suggestions from those with more experience? Thanks again....
If you have drains at the low spots congratulations on good maintenance planning You only have to worry about low spots that have lines full of water. Also people used compressed air to irrigation clear lines for winter. There are YouTube videos showing how to do this. The hard part is the connections for the compressor and how big of one to use. In your case low pressure or none at all would work. No more than about 5 psi to push water out the drains. GL JMHO Aloha
For what it's worth, I use polyethyene instead of PVC for my irrigation system. In the fall I open everything up, and let it drain.
PE tolerates short sections of full pipe. The ice plug just expands into the air space on either end. It also really reduces the number of fittings. A 300 foot supply line with two hosebibs on it (one for the projected greenhouse, one for a demo garden) took me about a half a day to put in. Dig a 2" deep x 2" wide groove in the sod with a grubhoe, lay the pipe, pinning it down with geotex staples, and cover it over, leaving the top showing now and then so I can find and follow it later. (This is a farm, not a show place.)
I learned early on to make sure my connections, which are more rigid, a few inches above the lie of the pipe. They don't like to freeze. Nor do taps.
In the spring I usually have a small amount of breakage. It takes me most of a day to get the system running and fix things. But i have 1500 feet of mainline, 10,000 feet of laterals, 9 hose bibs, and I buy drippers in boxes of a thousand.


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couple of owls
azant(10a)July 23, 2012
Found these little guys perched on my pistache tree
Pagancat(Phoenix, AZ)
I've heard it said that birds are the most adaptable wildlife to urban life...
... does anyone know of a medium sized light brown bird with white and brown stripes on its tail and wings, a dark breastplate that is almost heart shaped and red on it's throat, almost to its cheeks? It was rustling around in my gravel today.
These guys come around quite a bit, i see them sometimes fly from tree to tree in the evenings.
I got these shots probably around 9ish at night. Thanks for lookin guys. Glad there are others who appreciate these little guys. I wasn't sure what kind of owl they are, but they remind me of pygmy owls. They make a faint little noise not like a traditional owl sound or screech


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Winner of the 2014 Grand Cochon
Cook Pigs Heritage Pork was the centerpiece ingredient in the winning entry of Chef Ray Garcia of Fig Restaurant at the Grand Cochon 2014. The Grand Cochon is the grand finale of the Cochon 555 — a one-of-a-kind, ten-city culinary competition.
The Cochon US Tour is an epic porc feast featuring top chefs preparing whole heritage breed pigs, together with winemakers, brewers, distillers and craft food makers. The tour is described as a series of honest food events, a conquest for flavor. It has been heralded for creating a positive impact on local agriculture, highlighting America's family farms that raise heritage pigs. Cook Pigs Ranch is proud to be a part of this event which unites local farmers, renowned chefs, prominent winemakers, established restaurateurs, brewers, and distillers, as well as the pork loving public.
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brand news
Posted by Shirley Brady on March 25, 2015 08:58 AM
Kraft and Heinz are merging to form North America's third-biggest (and world's fifth-biggest) food giant.
Amazon is gobbling up Seattle to accommodate projected local workforce of 50,000 people.
Time Warner Cable disputes that it's losing one billion dollars annually on LA Dodgers channel.
Vessel subscription video streaming service goes lives as YouTube looks to expand live streaming.
BBC reportedly ends Jeremy Clarkson's contract, putting Top Gear future in doubt.Continue reading...
More about: Brand News, A&E, ABG, Amazon, Apple, BBC, BT, Burger King, Empire, Facebook, Ford, FOX, Gmail, Google, Heinz, Hershey, Hot Topic, Kraft, Mahindra, Ore-Ida, Orphan Black, PayPal, Pininfarina, Revlon, Scotts, Square, Tapout, TED, Time Warner Cable, Top Gear, Vessel, WeChat, Wendy's, WWE, Xiaomi, Yahoo, YouTube, Yum! Brands, Christina Aguilera, Halle Berry, Jeremy Clarkson, Olivia Wilde
Posted by Shirley Brady on March 3, 2015 07:54 AM
At Mobile World Congress in Barcelona, Pizza Hut responds to Domino's wearable move with beyond-the-waves in-car ordering with Visa Checkout ... Pebble reveals Steel smartwatch ... new phone reveals include BlackBerry's $275 Leap touchscreen phone ... Huawei plans big US push for wearable and mobile devices ... Facebook's Zuckerberg downplays Google's wireless plans and promotes Internet.org with partners ... AT&T connects car and home while partnering with Microsoft for small business ... Sony touts Xperia aqua for underwater shots ... Under Armour invests in health monitoring apps ... Telefonica details brand engagement-for-data pilot ... and Apple Watch spurs upgrade frenzy for Android devices.
At Geneva Motor Show, new car reveals include Lexus SF-SA concept ... Nissan unveils Sway concept ... Ford unveils new Focus ... Infiniti embraces bold design with QX30 concept ... Porsche unveils new 911 ... as Apple Car hangs over show—and Mobile World Congress, where Nissan-Renault CEO Ghosn welcomes Apple to the fray. Continue reading...
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in the spotlight
Posted by Sheila Shayon on February 9, 2015 10:34 AM
Machine learning is fast becoming a brand's new BFF, helping companies create actionable insights from big data to improve the customer experience and (hopefully) increase brand loyalty in this Age of You, as Interbrand calls it.
Amazon and Netflix are old hands at using algorithmic insights to recommend products to customers and personalize their brands, while Facebook uses it for photo identification and NASA to identify stars more quickly.
Pinterest is also diving in, having recently acquired Kosei, whose recommendation engine understands 400 million relationships between 30 million products.Continue reading...
More about: Personalization, Digital, Big Data, Machine Learning, Technology, Amazon, Netflix, Pandora, Pinterest, Adobe, Behance, Zillow, PayPal, Cisco, Dato, AI, Artificial Intelligence, Age of You, Interbrand
tech style
Posted by Sheila Shayon on November 12, 2014 03:06 PM
eBay is partnering with tech-savvy fashion brand Rebecca Minkoff to bring immersive digital technology to the designer's foray into brick-and-mortar stores.
The first of four high-tech boutiques will open on Saturday in New York's Soho area, followed by a San Francisco store (in the Pacific Heights neighborhood) that will open shortly thereafter and stores in Los Angeles (on Melrose Avenue) and Tokyo next year.
While the stores are permanent, eBay has signed on for a one-year (minimum) partnership to bring its e-commerce prowess to Minkoff's first stores, powering touch screen interactive displays and digital fitting rooms designed with her customers—omnichannel-savvy, sophisticated and fashion-forward shoppers—in mind.Continue reading...
More about: Retail, eBay, Rebecca Minkoff, Mobile, Apps, E-Commerce, Partnerships, Digital, Omnichannel, Technology, Interactive, Luxury, Design, Fashion, Apparel, Shopper Insights, Big Data, eBay Now, PayPal
Posted by Dale Buss on November 12, 2014 09:24 AM
GM cuts workforce and slows production at small-car assembly plant in push for change, while Volvo cuts up to 3,000 people to boost profitability.
Walmart adopts rolling approach to Black Friday as it focuses on improving grocery performance and promotes the pursuit of happiness.
Yahoo acquires video-ad platform BrightRoll as some unhappy big investors lobby AOL to acquire Yahoo.
Alibaba may work with PayPal on payments.
Mondelez invests in Vietnam snack market.Continue reading...
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Posted by Dale Buss on October 16, 2014 09:09 AM
Apple accidentally leaks new iPads on iTunes ahead of today's reveal.
CBS mulls confirms offering online version of Showtime in response to HBO's standalone video announcement.
Clorox leads Ebola-related surge in sales of hand disinfectants.
Walmart warns about rough patch for sales and profits but makes progress with smaller stores and e-commerce.
Wendy's grows presence on Facebook as McDonald's pushes to become biggest brand on Facebook with 14,500 pages.Continue reading...
More about: Brand News, AbbVie, Amazon, Apple, AT&T, Audi, BMW, Barbie, CBS, Chobani, Clorox, Coca-Cola, Cracker Jack, Denny's, eBay, Facebook, FEED, Ford, GLAAD, GM, HBO, Heineken, Honda, iPad, Jimmy Choo, Johnny Rockets, Kia, Macy's, Martha Stewart, Mattel, McDonald's, Meredith, Microsoft, Oculus Rift, Netflix, PayPal, Pizza Hut, Sainsbury's, Shire, Showtime, Toyota, Volvo, Waitrose, Walmart, Wendy's, Yahoo, James Van Der Beek, will.i.am
Posted by Dale Buss on October 2, 2014 07:14 AM
PepsiCo launches Pepsi True "mid-cal" as new salvo in cola wars, exclusively at first on Amazon.
Netflix books Adam Sandler for four movies while France's Orange plans to market the service in November.
Ford partners with culture brands and publishers to create "road trips" for new Mustang.
Volkswagen, Porsche and Lamborghini roll out plug-in hybrids in Paris.
Tesla hints at timing for unveiling Model "D."Continue reading...
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Posted by Sheila Shayon on September 30, 2014 11:01 AM
Call it a "Conscious Uncoupling." Or more accurately, an "Icahn-scious Uncoupling." After months of lobbying by activist investor Carl Icahn, PayPal is splitting from parent eBay and will become a separate, publicly traded company next year.
In its announcement today, eBay said the board made the decision as the best path for growth and shareholder value creation for each business going forward—and already, eBay shares jumped more than 11 percent in pre-market trading.
In tandem with the news, Dan Schulman was named the new president of PayPal, joining the company from president of the enterprise growth group at American Express and previous roles at AT&T, Priceline and Virgin Mobile. eBay veteran Devin Wenig becomes CEO of the new eBay, replacing current president and CEO John Donahoe.
While the companies already operate fairly independently, the move will free each entity to grow and thrive—assuming all goes to plan—even though eBay stands to lose half its revenue as a result of the separation.Continue reading...
More about: eBay, PayPal, E-Commerce, Mobile Commerce, M&A, Online, Retail, Financial Services, Mobile Payments, Apple Pay, Alibaba, Carl Icahn
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by Tara Culp-Ressler Posted on February 23, 2015
When famous people become the brand ambassadors for women's issues, nothing is ever clear-cut.
by Jessica Goldstein Posted on February 19, 2015 Updated: February 19, 2015
Talking to the women behind the Ask Her More campaign.
by Katie Valentine Posted on January 18, 2015
Pope Francis said he wished there were more women in the crowd he addressed in the Philippines Sunday.
by Jessica Goldstein Posted on December 11, 2014 Updated: December 12, 2014
Minaj doesn't need anybody else to get off, thankyouverymuch.
by Carimah Townes Posted on December 3, 2014 Updated: December 9, 2014
Recaps of the year can be so silly.
by Beenish Ahmed Posted on November 9, 2014 Updated: November 11, 2014
while Boko Haram, ISIS, and the Taliban have all waged a bloody reign of terror in seeking to achieve these goals, it's the crimes they commit against schoolgirls – archetypes of innocence and vulnerability – that earn them the most disdain.
by Jessica Goldstein Posted on November 5, 2014
"Sidewalk": like if "10 Hours Walking as a Woman In New York" was a cartoon and covered 100 years.
by Lauren C. Williams Posted on October 23, 2014 Updated: October 23, 2014
Day said she's kept quiet out of fear of getting doxxed or hacked.
by Jessica Goldstein Posted on October 10, 2014
D.C. Judge ruled that upskirt photos are totally fine, women have no expectation of privacy for their private parts in public places. Makes sense to me!
by Tara Culp-Ressler Posted on October 10, 2014
"Yes Means Yes" definitions for consent are taking off in states across the country.


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need help for making a DNA model
jippyJanuary 21, 2003
Our son is doing his science fair project on DNA. Does anyone out there have any ideas how we cam build a double helix model of DNA? Any ideas will be greatly welcomed! :) Many thanks in advance.
Here is one of them:
Try searching google with 'dna double helix model', you will see bunch of hits.
Here is one of them:
Science with a Twist