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Plant looks like cilantro, but doesn't smell like cilantro
I have several cilantro plants that I grew from seeds. My cilantro hasn't bolted yet. But this plant is growing around them. I did sow more cilantro seeds once the first seeds started to grow, but this plants doesn't look alike. I smelled the leaves and it doesn't have a distinctive smell. After crushing some leaves between my fingers I noticed a subtle mint smell, not strong enough.
I am new gardener and I forgot to put a sign where the seeds were placed. I have sowed mixed lettuce, cilantro, peppers, spinach and recao (wild cilantro). The only ones that hasn't sprout are peppers and recao. I know very well the recao plant and it doesn't look like this one. Neither looks like lettuce or spinach or pepper.
Is it a weed?
Thanks in advance!
Looks like Wild Chervil (Chaerophyllum procumbens).
Here is a link that might be useful: Wild Chervil


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Recent Heber Reviews
Fantastic experience in this cute cabin
This adorable little cabin was perfect for a getaway with my fiancee and our pup. I can't emphasize how CLEAN it was. Even the floors were spotless - it was impressive. We highly enjoyed our stay here, it's situated close enough to so much hiking that we were able to get a lot in during the day and cook our own dinners and relax at night back at the cabin. With a space heater and gas fireplace, it was easy to warm this place right up in the winter. There are plenty of trees on the lot, but it is in the middle of a bunch of other vacation cabins. This really wasn't an issue for us, as it was very quiet this time of year. We enjoyed our time in the hot tub watching the stars (GREAT STARGAZING OUT THERE) and there were no other people around outside. Overall, we had an absolutely wonderful stay. Thanks for a lovely place and most of all, thank you for having it so clean!

subset: commoncrawl


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Leopard Print Zip Pocket Bag
Tom Ford
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Christian Louboutin
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Christian Louboutin leopard-print patent leather clutch bag. Shiny gunmetal hardware. Removable chain shoulder strap; 10" drop. Curved front flap with magnetic-snap corners. Flap secures chain detail with hanging logo medallion. Inside, one zip and one open pocket. Christian Louboutin signature red faille lining. 5 1/2"H x 10 1/4"W x 2 1/2"D; weighs 1 lb. "Riviera" is made in Italy.
Calf Hair & Mink Fur Shoulder Bag, Leopard/Black, (Miele/Moro)
Prada leopard-print dyed calf hair (Italy) and dyed mink (Denmark) shoulder bag. Golden hardware and soft leather trim. Double-chain shoulder straps; 12" drop. Flap front with engraved push-lock clasp. Hanging covered key charm. Expandable zip-around bottom. Inside, leather lining; one zip and two slide pockets. 6"H x 10 1/2"W x 2"D; weighs 1lb. 12oz. Made in Italy.
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The Church needs a new âmissionary dynamicâ of lay people and must pay âparticular attention (to) baptized people who do not live according to the requirements of the baptism,â he said as 262 bishops wound up a three-week huddle that broached all major issues and crises shaking the 2,000-year-old institution.
Clerics must also apply ânew methods, a new language that suits different culturesâ in their bid for a ânew evangelism,â he said during a closing mass at Saint Peterâs. ...
But getting back to bent Catholic priests, Irish priest comes out as gay to congregation, receives standing ovation. The Romish Church is queer the world over. Apparently queer priest their wants to make Irish Repub, queer friendly.
Thanks for noticing, Mike.
Jim Lincoln wrote:Things have about child abuse have been rather quiet on the Down-Under front, but one does have to remember that the Romish is universal -- in its molestation of Children. Just busy busy helpers of Satan ---
Are We Really Catholic Bashing?. No, just the organization, we want Come out of the Catholic Church
What Catholics Don't Know
Are Roman Catholics Christians?. Nice example of a Chick tract.
I saw this on my trusty tablet as well. the new Chicago Cardinal has already had to apologize for a child abusing priest apparently. http://chicagosuntimes.com/news/cupich-apologizes-for-horrible-things-done-by-former-priest/
Ah, the SNAP organization is in Australia, and you can see how that was started in the video that is in this article, The Fight to Reveal Abuses by Catholic Priests which includes video on bishops. Now, they're American Bishops but I'm sure that Romish Bishops are the minions of Satan no matter where in the world they are. Are We Really Catholic Bashing?
Roman Catholicism
Also the Catholic-lite church, "The Anglican one trying to ape the Mother Church, Anglican clerics hostile in child sex abuse dealings, royal commission says.
"The NSW Police Integrity Commission is investigating the possible misconduct of senior police officer, Inspector Elizabeth Cullen, who says it wasn't her responsibility to report sexual abuse cases during the six years she sat on an internal panel of the Catholic church." from the above news story that has a transcript with it.
David Shoebridge wrote:It became apparent that there was a formal memorandum of understanding between the police and the church we saw this police officer engaged on the internal church committee. And then when we asked for the details of the evidence that had been given to that police officer, we were told that there was a protocol in place that either all the evidence was returned by the police officer or anything that was retained by the police was shredded.
By the way, Jesus Christ, Our One & Only High Priest and Requirements of Every High Priest since the Reuters one mention His Unholiness Franny quite a bit.
s c wrote:Francis, the talking "pope" (hoggardism) stated: "Clerics must also apply ânew methods, a new language that suits different culturesâ in their bid for a ânew evangelism,â he said during a closing mass at Saint Peterâs. ..." If only he would try out the blueprint in the real Bible. Then they wouldn't need "relevant, new" methods. It's really so simplistic: Faith comes by hearing the Word of God.


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AOL is hoping to take advantage of a predicted surge in spending on digital-video advertising with a multimillion-dollar buyout of Adap.tv, a developer of software that facilitates video-ad sales. "The combination of AOL and Adap.tv is expected to create the only global company with a full end-to-end solution and video stack for publishers and advertisers," AOL said of the $405 million acquisition.
View Full Article in:Hollywood Reporter (free content), The
Published in Brief:


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Clever 'Fresh Prince' Prank Call Livens Up C-SPAN
This C-SPAN caller was up to no good in someone else's neighborhood.
This C-SPAN caller was up to no good in someone else's neighborhood.
Anna Kendrick, John Krasinski, Jimmy Fallon and more celebs face off in the new reality TV competition Lip Sync Battles, premiering April 2 on Spike.
The Maine Drug Enforcement Agency arrested a man this week for trafficking in cocaine. Along with the drugs, agents seized cash and firearms.
Fans of History Channel's recently canceled show 'Down East Dickering' to host meet and greet event in hopes of bringing back their favorite show.
It's that time again! Netflix is adding a bunch of new titles to their streaming service in April for your viewing pleasure, including Marvel's new Daredevil series, but that's not all. There are some great titles on this list, from old classics to new favorites, and a few gems for you to discover. New additions include Noah and Hot Fuzz, as well as a few of last year's best horror films. Read on for your guide to the new releases hitting Netflix Instant in April.
Madonna posted a photo of herself stealing a kiss from Justin Bieber while both were backstage filming The Ellen Degeneres Show.
Hey, America. You need to relax.
Presumably to help get Foxx into character, Tyson put together a 57-minute collection of every single one of his knockouts, and it's one of the best things we've ever seen.
Christina Aguilera just drastically changed her hair color -- and it's all for 'Nashville'!
Bad news for adults too lazy to cook and parents of kids who are picky eaters.


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Joss Stone News
Similar Artist News
Here's Why Pop Lyrics Tend to Make You So Sad
It turns out the English language is downright depressing.
Blast These 15 Girl Power Tracks for International Women's Day
All the women, independent, throw your hands up at me!
Here's A List Of Songs Turning 10 in 2015 That'll Make You Feel Super-Old
So you're telling me "Get Back" is ten years old? That's Ludacris!
Christina Aguilera's Impression of Britney Spears Is Perfect
Especially with "This Little Piggy" as the song subject.
Ed Sheeran Puts His Spin On A...Christina Aguilera Classic?
Watch the singer/songwriter get "Dirrty" for BBC Radio 1 in the Live Lounge
Our Favorite Musical Moments from the 2015 Oscars
Glory! The Sound Of Music! Everything Is Awesome! Relive all the best musical Oscar moments with us
Obviously Beyonce's Tribute To Stevie Wonder Was "Flawless"
She could totally lead a rock band with Ed Sheeran and Gary Clark, Jr. Don't believe us? Just watch
Love Stinks, So Here's 15 Anti-Valentine's Day Songs
We can't forget about all the haters out there. These are dedicated to all the non-romantics!
Kelly Clarkson Comments On Fans' Heartwarming Stories Shared On Her Lyrics
The singer interacted with some of her fans most touching memories on her website.
14 Love-Grams Featuring Your Fave Pop Lyrics
Nicki Minaj, Taylor Swift, Ed Sheeran — we've got all their lyrics covered this V-Day
13 Unforgettable Moments from the 57th GRAMMY Awards
The biggest moments from music's biggest night.
POLL: Who Should Win at This Weekend's GRAMMYs?
Cast your vote for who deserves to take home awards in the biggest categories.
It Takes Two! These Duos Will Blow You Away At The GRAMMYs
Check out the list of 2015 GRAMMY pairings who'll take the stage together on Feb. 8th
Watch Sam Smith, Ariana Grande and More Sing "We Are The Champions" With Jimmy Fallon
It's a seriously epic all-star rendition.
Is This The Most Random GRAMMYs Performance Lineup Ever?
The 2015 awards show will host a bevy of totally different music genres — not to mention generations
Share Your Thoughts On Kelly Clarkson's 'Piece by Piece' Lyrics
The pop star's seventh studio album drops March 3rd! She's got a cool new lyric feature for her fans in the meantime
WATCH Maroon 5 Crash a Bunch of Weddings
Their "Sugar" video has the M5 boys giving brides & grooms the surprise of a lifetime
Here's Every Song Nominated for a 2015 Oscar
Do you think all these Best Original Song nominees deserve a nod? Have a listen to each of 'em & tell us what you think
Find Out If Your Fave Artist Scored A 2015 People's Choice Award
Did Taylor Swift win big? What about Ed Sheeran?
11 Of The Funniest Misheard Lyrics Ever (Submitted By You!)
Seriously, we're falling off our chairs here at how hilarious some of these misheard lines are
Madonna's Leaked 'Rebel Heart' Tracks: Ranked
How do Madge's latest crop of songs from her upcoming LP stack up? We analyzed 'em track by track
This Hilarious Misheard Lyrics Video Will Force You to Rethink Your List of "Starbucks Lovers"
It's the 2014 edition of Pleated Jeans' annual collection of misheard lyrics!
Best Albums of 2014: Amanda's Top 10 Picks
See who made my list of the most-spun records of the year!
Ring In 2015 With Our All-Night New Years Playlist
Live it up this NYE by blasting our Spotify / YouTube playlist featuring 2014's best hits + party favorites
Get All The Lyrics To Nicki Minaj's Epic New Album 'The Pinkprint'
What song is your favorite? We can barely begin to pick just one...
Who Will Win 'Album Of The Year' At The 2015 GRAMMYs?
Beck, Beyonce, Ed, Sam, or Pharrell? How do we pick between these five amazing talents...
Our Pop Xmas Playlist Might Make You Drop Your Shopping List & Dance
Don't say we didn't warn you. Here's our ultimate Christmas pop playlist on Spotify and YouTube!
Can You Name All The Hits In YouTube Rewind's 2014 Video?
You'll be "Happy" to know that YouTube included all the years' "Fancy" singles in its annual Rewind video compilation
Your Guide To The Best New Releases Dropping December & Beyond
Brought to you by Pause & Play, here's a list of forthcoming music you'd be crazy to miss out on
Year of the Booty: The 10 Best Songs About Buns, Hun
These ten tracks give love to the derriere like nobody's business. My Anaconda don't!
GRAMMY Nominations Preview 2014: Find Out Our Predictions
We're listing out who we think could take home a GRAMMY or two this year -- tune in to the announcement on Dec. 5th
5 Songs Perfect For Rocking Out To In Your Underwear
For those occasions when you're just soooo over clothes.
Ladies Be Killin' It: Our Favorite Female Pop Tracks of 2014
We're bringing you fifteen of our fave pop tracks from the best ladies on the charts this year. Press play!
OMG, Gwen Stefani's Back In "Spark The Fire" Video
Let's spark the fire: who's got a lighter?
15 Dollar-Dropping Songs for Black Friday
Today is all about the Benjamins, baby!
10 New Pop Tracks We're Thankful For This Thanksgiving
On this day, we're thankful for Selena, Nicki, Queen Bey and more...
The 10 Best Performances At The 2014 American Music Awards
5SOS, Charli XCX, One Direction, Selena Gomez...the list goes on and on and on...
Is '7/11' The Best Beyonce Music Video Of All Time?
Taken from her platinum edition of 'BEYONCE', Queen Bey NAILS her new DIY video!
Watch Band Aid 30's "Do They Know It's Christmas?" and Help Stop Ebola
Can you spot all the stars in the latest Band Aid roundup? Listen to the reworked song and help fight the Ebola virus
Carrie Underwood Forgets Her Umbrella in "Something In The Water"
The country superstar doesn't let a little rain bother her in the brand-new video...


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Cream butter with sugar until light and fluffy.
Add egg yolks one at a time, beating after each addition.
Stir in brandy, macaroon crumbs and peaches.
Beat egg whites with salt until stiff.
Fold into peach mixture.
Pour into a buttered 1 1/2-quart casserole.
Bake in a 325° F oven 30 to 40 minutes or until browned.


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WINSTON-SALEM, N.C. – University Dental Associates (UDA) has opened a brand new general dentistry office in western Forsyth County near the intersection of Interstate 40 and Lewisville-Clemmons Road. The practice is located in the Clemmons Village West development behind Panera Bread, at 6201 Towncenter Drive, Suite 130 in Clemmons. "We are very excited to open this high quality practice and facility in Clemmons to better serve our patients in Forsyth, Davie and Iredell counties," said Raymond Garrison, D.D.S., M.S., president of UDA. Staff from the UDA CompRehab office will help professionally staff the new facility. Bruce Rogers, D.D.S., who has been providing comprehensive general dentistry with UDA since 1999, will lead the office team of dental hygienists, Kelly Welch, R.D.H., dental assistant Kia Smalls, D.A. II, and receptionist Tabitha Whitaker. UDA is accepting new patients at both the CompRehab and Clemmons practices. Patient clinical and financial records can easily be transferred between the two locations. For more information or to schedule an appointment at the Clemmons office, please call 336-778-9199. ###Media Relations Contacts: Lisa Davanzo, firstname.lastname@example.com, at (336) 716-6906; Bonnie Davis, firstname.lastname@example.com, at (336) 716-4977 or Shannon Koontz, email@example.com, at (336) 716-2415.
Media Inquiries 336-716-4587Patient Information 336-713-0000Satellite Interviews 336-716-4434
On March 20, seniors at Wake Forest School of Medicine learned where they will begin their careers as doctors at Match Day, an annual event at which graduating medical students learn where they'll be doing their residencies. This year 113 Wake Forest medical students, 59 men and 54 women, matched in 20 specialties.
Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.


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Thanks for visiting! If you're new here, you may want to subscribe to My Newsletter. Please Note: This post may contain sponsor, affiliate, and/or referral links. Read my full disclosure and disclaimer statement here.
Calming Hot Chocolate
Sugar Free
I love a good hot chocolate when I am cold. I'm pretty much in love with hot chocolate right now. I want a nice warm drink to have once the kids go to bed and I'm sitting next to Adam relaxing before bed.
This is the most relaxing hot chocolate you will find. It is full of peaceful and soothing ingredients that will help you fall asleep and rest well.
Hot chocolate is such a comforting drink and it is pretty healthy too!
I use stevia as my sweetener, because I have trouble controlling my blood sugar using other natural sweeteners. This keeps it sugar free and helps keep your blood levels balanced before going to bed.
Magnesium is also added to this calming hot chocolate recipe to help increase the relaxing benefits. Magnesium is a wonderful mineral for your health and many people are deficient in it. When you are deficient, you have more issues with insomnia and waking up during the night. Adding this powerful mineral to your calming hot chocolate will help you increase your magnesium intake easily. More on easy ways to increase your magnesium here. Try my Apple Night-Night Gummies Recipe to help your kids get their magnesium.
- 4 cups of water
- 2 tea bags of chamomile tea
- 1 teaspoon of Stevia English Toffee liquid (Or your preferred sweetener)
- pinch of salt
- 2 tablespoons of cocoa powder
- 1 rounded teaspoon of natural calm magnesium powder
- Boil your tea bags in water and let sit for 5 minutes for tea to seep.
- Add all ingredients to blender.
- Blend for 1 minute.
- Serves 2 large mugs.
What are your favorite night time drinks?
Angela Parker
Latest posts by Angela Parker (see all)
- Do you want to learn more about That Crazy Wrap Thing? - February 23, 2015
- Febuary Friday Weekly Wrap Up - February 20, 2015
- How Sara Replaced her teaching job to be a Stay at Home Mom - February 20, 2015


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Star Ship Polaris
View Single Post
March 20 2008, 05:18 PM
aridas sofia
Rear Admiral
Re: Star Ship Polaris
If you can create a space warp, you can create much, much more gravity than a star. Of course, we are talking apples and oranges, because the question isn't really about how much, as about how much in what amount of space. In any event, I'm not saying a gravity field would be used -- that would be
. I'm saying a negative energy and/or exotic matter-generated
field. A
field. Remember, the purpose of such a field is to keep open the fabric of space that has been warped by intense gravity -- a microsingularity or some other source -- at the ship's bow. Absent an antigravity field amidships, the fabric of space would collapse and create (I think) a black hole. The ship would be destroyed. The antigravity keeps the "throat" open, and creates something akin to (again, I think) a wormhole. The ship then has another hypergravity source at the stern to close the breach and restore the fabric of space to its natural geometry.
Last edited by aridas sofia; March 20 2008 at
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At guests 'disposal there are three large bedrooms, a triple (Laura room) with balcony facing the garden, a double... Más información »
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A B&B few steps from historical centre of Verona .The Bed And Breakfast La Magnolia is located 450 mts far from... Más información »
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we have three combinations of rooms: Single GREEN Single room with internet WI-FI, wardrobe, shared balcony,... Más información »
The owner, Mrs. Mariella, is pleased to welcome you to the B&B Al Parco, located in the residential district of Borgo... Más información »


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'SRK should get out of India'
If he has such a strong admiration and liking for Pakistan, then Shahrukh should get out of India and move to Pak. We've had enough already. If SRK wants to praise Pakistan, he is free to go and live in that country too.
SRK should know that he is an India first and India, who has gained popularity and money here. We also heard that he has invested his money in Dubai. Well he owns his success to the Indian public. If he is really loyal to Pakistan, he should go there and lead a peaceful life.
on Nov 23, 2014 , 01:34 am
srk old fello my mother is younger then him n he is doing films yukkkkkkkkkkkkk
on Nov 21, 2014 , 04:41 pm
he should kick out of india for giving coomments on our pm
on Nov 21, 2014 , 04:41 pm
Bono Vox replies to Idea Maker
Truly srk muslim should be kick out of India.
on Feb 08, 2015 , 08:22 pm
How can you say SRK should get out of India'? We are living in independent country, nobody has rights to say somebody should leave the country.
on Nov 20, 2014 , 09:06 am
interesting article.... thanks fr sharinggg
on Jul 02, 2014 , 02:53 am
No. Not at all. We are democratic country and all individual has right to have their view. There are Indian managed companies like Birla group, Centrepoint etc which gives employment to Pak nationals and these organisation are honored by Indian Government for their work.
on Jun 03, 2014 , 01:29 pm
Modi has not invited him to his party, despite having invited Salman Khan.
on May 23, 2014 , 11:14 pm
go away SRK
on May 19, 2014 , 09:43 pm
on May 14, 2014 , 03:43 pm
on Apr 28, 2014 , 09:04 pm


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The book was endearing and the intrigue and suspense keeps one wanting more. A very enjoyable read! I would recommend to anyone who loves cooking.Published 1 day ago by Rosaria Campanile-Minneci
I read this and had to buy a copy for a friend of mine in Charleston, SC the land of delicious restaurants and she loved it.Published 2 days ago by Bobbie Martin
It is important to read this book to the end, where some of the most important reflections occur. The somewhat lightweight writing camouflages the feeling and insight underneath. Read morePublished 3 days ago by Steven L. Griffin Sr.
Although it was a bit on the predicable side, there were a few surprises along the way. I really enjoyed this book very much. Would highly recommend it. Read morePublished 3 days ago by Lynette C. Woide
The story is different than other books I have read. A girl follows her dreams and does well in the world of gormet food.Published 7 days ago by jim smith
Kind of fluffy; a feel good story if you're not in the mood for anything heavy or controversial. I did have a hard time following who some of the characters were and some of the... Read morePublished 7 days ago by Matthew R. Bailey
Such a nice story with amazing pieces of history that made me hungry for cake, pasta and cheese! NYC as a backdrop never fails.Published 7 days ago by Jodi L Andrews
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Songwriter and producer Tom Krell makes stirring, lush avant-R&B under the guise of How to Dress Well. After two critically adored albums that reinterpreted influences like Janet Jackson and Bobby Brown—and spawned genre portmanteaus like PBR&B—Krell released his third, What Is This Heart?, in June.
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Phi Phi Island Cabana Hotel
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TravelPod Member ReviewsPhi Phi Island Cabana Hotel Ko Phi Phi Don
This place is ideally situated so that you can actually see both sides of the island if standing at the right spot. Place was great.
This review is the subjective opinion of a TravelPod member and not of TravelPod.com.
TripAdvisor Reviews Phi Phi Island Cabana Hotel Ko Phi Phi Don
Travel Blogs from Ko Phi Phi Don
Day 9: Boat Trip and Beach PARTY!!
You know how there is that tropical beach background on most computers? All I kept thinking today was "OMG, I am at the place where they took that photo!"
From start to finish, today was an amazing day.
It began with a boat trip around Phi Phi …
Moped Mishap
... triage site good to go Gord started the arduace task of trying to scrub the dirt out of freshly torn flesh,while Leon ran all over getting the necessary supplies.We were told at the clinic,absolutely no sea water or tap water,so the guys had saline powder for their noses and we got tons of bottled water,as well as super cleaner for the sink,so that I could get my let in the basin and Gord could really clean it properly!followed by a dowsing of iodine(more screaming) ...
We meet Wasim and his team
... none of this could detract in any way from the fun and pleasure we enjoyed during our stay. If we do end up returning to Krabi in the future, we will feel treacherous if we stay anywhere else!
We fell into a semi regular routine during our stay which was to go into town in the morning, spend a few hours on the beach and then stay for lunch in town. If we needed further entertainment we would pop back to Orange City, have a session in the swimming pool ...


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Publications (54)125.53 Total impact
Article: The prognostic effect of Ki-67 expression in R-CHOP-treated diffuse large B-cell lymphoma is limited to non- germinal center B-cell-like subtype in late-elderly patients.[Show abstract] [Hide abstract]
ABSTRACT: Abstract This study evaluated the effect of age and cell of origin on the prognostic significance of Ki-67 labelling index (Ki-67 LI) on overall survival (OS) of diffuse large B-cell lymphoma (DLBCL) in a cohort of 697 patients treated with rituximab plus CHOP (R-CHOP). Multivariate analysis revealed no prognostic significance of high Ki-67 LI (≥ 85%) for OS. However, on subgroup analysis, high Ki-67 LI was significantly associated with poor OS in late-elderly (aged ≥ 70 years) (P = 0.021) and non-germinal center B-cell-like (GCB) subtype (P = 0.015). In particular, high Ki-67 LI was associated with poor prognosis in late-elderly non-GCB patients. No correlation was observed in young adults (aged < 60 years) or early-elderly (aged 60-70 years) or GCB patients. Present study shows that high Ki-67 LI is a risk factor of poor OS in late-elderly age group and non-GCB subtype in DLBCL patients treated with R-CHOP.
Article: The First Case Report of Composite Bone Marrow Involvement by Simultaneously Developed Peripheral T-Cell Lymphoma, Not Otherwise Specified, and Diffuse Large B-Cell LymphomaAnnals of Laboratory Medicine 01/2015; 35(1):152-4. DOI:10.3343/alm.2015.35.1.152 · 1.48 Impact Factor
Article: Clinical features and outcomes in patients with human immunodeficiency virus-negative, multicentric Castleman's disease: a single medical center experience[Show abstract] [Hide abstract]
ABSTRACT: Multicentric Castleman's disease (CD) is commonly associated with poor prognosis, and well-known prognostic factors are scarce. We performed a retrospective analysis to define the clinical features and prognostic factors for patients with multicentric CD. Between 1990 and 2013, 32 patients with multicentric CD were identified from the database of the Asan Medical Center, Seoul, Korea. Clinicopathologic data were collected by reviewing the medical records. With the exclusion of 4 patients because of unknown human immunodeficiency virus infection status, 28 human immunodeficiency virus-negative patients with multicentric CD were included in this analysis. Most of the patients were male (76%) and had a median age of 54 years. Hyaline vascular variant was the most common subtype (N=11, 39%). Hepatosplenomegaly (61%), fever (39%), edema (29%), and ascites (18%) were the most frequently reported symptoms and signs at diagnosis. With a median follow-up of 67 months, the 5-year overall survival (OS) was 77%. Patients with extravascular fluid accumulation (i.e., peripheral edema, ascites, and/or pleural effusions) were significantly associated with a poor survival rate (5-year OS, 94% vs. 56%; P=0.04). The extent of disease involvement was also a significant prognostic factor (5-year OS, 91% for involvement on a single side vs. 73% on both sides of the diaphragm; P=0.03). Other clinicopathologic factors were not significantly associated with patient survival. Our findings suggest that the hyaline vascular variant is not a rare subtype of multicentric CD. Extravascular fluid accumulation and disseminated disease involvement seem to be significant prognostic factors.12/2014; 49(4):253-8. DOI:10.5045/br.2014.49.4.253
The Korean Journal of Pathology 10/2014; 48(5):394-7. DOI:10.4132/KoreanJPathol.2014.48.5.394 · 0.17 Impact Factor
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ABSTRACT: Here we report a case of a 76-year-old man with diffuse large B-cell lymphoma (DLBCL) with simultaneous involvement of the right breast and left testicle. The patient underwent complete resection of the involved testis, followed by immunochemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP) and prophylactic radiotherapy to the contralateral testis. Following this multimodal therapy, he achieved a complete response. This is a rare case of DLBCL involving both the breast and the testis in a male patient.Cancer Research and Treatment 09/2014; DOI:10.4143/crt.2013.245 · 2.98 Impact Factor
Article: Treatment of primary testicular diffuse large B cell lymphoma without prophylactic intrathecal chemotherapy: a single center experience[Show abstract] [Hide abstract]
ABSTRACT: Primary testicular diffuse large B-cell lymphoma (DLBCL) is a rare but aggressive extranodal lymphoma, and its relapse in the central nervous system (CNS) is a major concern during treatment. Despite this, the role of intrathecal prophylaxis in primary testicular DLBCL remains controversial.09/2014; 49(3):170-6. DOI:10.5045/br.2014.49.3.170
Article: Abbreviated chemotherapy for limited-stage diffuse large B-cell lymphoma after complete resection[Show abstract] [Hide abstract]
ABSTRACT: BackgroundAbbreviated chemotherapy followed by radiotherapy or full cycles of chemotherapy is recommended as a standard treatment for limited-stage (LS) diffuse large B-cell lymphoma (DLBCL). After complete resection of tumors, however, Burkitt and childhood B-cell Non-Hodgkin lymphoma show favorable outcomes, even after abbreviated chemotherapy of only 2 or 3 cycles. We investigated the effectiveness of abbreviated chemotherapy in patients with LS DLBCL after complete tumor resection.MethodsWe retrospectively reviewed 18 patients with LS DLBCL who underwent complete tumor resection followed by either 3 or 4 cycles of chemotherapy between March 2002 and May 2010.ResultsWith a median follow-up period of 57.9 months (range, 31.8-130.2 months), no patients experienced disease relapse or progression; however, 1 patient experienced secondary acute myeloid leukemia during follow-up. The 5-year progression-free survival rate and overall survival rate were 93.3% and 94.1%, respectively.ConclusionThese results warrant further investigation into abbreviated chemotherapy as an alternative treatment for patients who have undergone complete resection of LS DLBCL.06/2014; 49(2):115-9. DOI:10.5045/br.2014.49.2.115This article is viewable in ResearchGate's enriched formatRG Format enables you to read in context with side-by-side figures, citations, and feedback from experts in your field.
Article: Cutaneous extranodal natural killer/T-cell lymphoma: A comparative clinicohistopathologic and survival outcome analysis of 45 cases according to the primary tumor site[Show abstract] [Hide abstract]
ABSTRACT: Background Differences in survival outcomes and prognostic factors of cutaneous extranodal natural killer/T-cell lymphoma (ENKTL) depending on primary tumor site are currently unknown. Objective We sought to analyze the clinicopathological features and survival outcomes of cutaneous ENKTL according to primary tumor site. Methods In all, 45 patients with cutaneous ENKTL were classified with: (1) primary cutaneous ENKTL, or (2) nasal ENKTL with cutaneous involvement. Clinicopathologic features, survival outcomes, and prognostic factors were analyzed using patient's medical records. Survival outcomes were analyzed using the Kaplan-Meier method and compared using the log rank test. The Student t test, Fisher exact test, and linear by linear association test were used to analyze clinicopathologic differences between groups. Results Clinical manifestations of cutaneous ENKTL included solitary or multiple subcutaneous nodules and cellulitis or abscess-like lesions. Primary cutaneous ENKTL demonstrated a less aggressive clinical course and better survival outcomes. The extent of cutaneous lesions demonstrated a significant effect on the prognosis of primary cutaneous ENKTL, but not on nasal ENKTL with cutaneous involvement. The presence of nasal lesions in primary cutaneous ENKTL was associated with poor prognosis. Limitations This study used a retrospective design and included a small sample size. Conclusion Although the clinicopathological features were similar regardless of subgroup, survival outcomes and prognostic factors differed depending on the primary tumor site of cutaneous ENKTL.Journal of the American Academy of Dermatology 06/2014; 70(6). DOI:10.1016/j.jaad.2013.12.023 · 5.00 Impact Factor
Article: Expression of CD99 in Multiple Myeloma: A Clinicopathologic and Immunohistochemical Study of 170 Cases[Show abstract] [Hide abstract]
ABSTRACT: BackgroundMultiple myeloma (MM) is a heterogeneous and ultimately fatal disease. Risk stratification using prognostic biomarkers is crucial to individualize treatments. We sought to investigate the role of CD99, a transmembrane protein highly expressed in many hematopoietic cells including subpopulations of normal and neoplastic plasma cells, for MM risk stratification.MethodsCD99 expression was measured in paraffin samples of bone marrow and extramedullary biopsies of 170 patients with MM. Patients were divided into those with high score (moderately and strongly positive) and low score (negative and weakly positive), with all staining being cytoplasmic and/or membranous.ResultsHigh anti-CD99 immunostaining was observed in 72 of 136 (52.9%) bone marrow biopsies and 24 of 87 (27.6%) extramedullary biopsies in MM. High CD99 expression of extramedullary specimens was associated with significantly longer overall survival (OS; p=.016). High CD99 expression of extramedullary specimens was also associated with better prognosis in the nonautologous stem cell transplantation group of MM patients (p=.044). In multivariate analysis, International Staging System stage was an independent prognostic factor, whereas CD99 expression was no longer statistically significant.ConclusionsExpression of CD99 in extramedullary specimens was correlated with longer OS, suggesting that CD99 may be a helpful immunohistochemical marker for risk stratification.The Korean Journal of Pathology 06/2014; 48(3):209-16. DOI:10.4132/KoreanJPathol.2014.48.3.209 · 0.17 Impact FactorThis article is viewable in ResearchGate's enriched formatRG Format enables you to read in context with side-by-side figures, citations, and feedback from experts in your field.
Article: Differential Expression Patterns of a Disintegrin and Metalloproteinase With Thrombospondin Motifs (ADAMTS)-1,-4,-5, and-14 in Human Placenta and Gestational Trophoblastic Diseases[Show abstract] [Hide abstract]
ABSTRACT: Context.-The ability of intermediate trophoblasts to invade maternal tissue during placentation depends on how well they can degrade the extracellular matrix. Invasion into the extracellular matrix requires many complex proteases. A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) is a novel family of secreted metalloproteinases. The ADAMTS-1, -4, -5, and -14 subtypes are known to be expressed in human placenta, but little is understood about their expression patterns. Objective.-To examine the expression patterns of ADAMTS-1, -4, -5, and -14 in specific human placenta cell types during gestation and in gestational trophoblastic diseases. Design.-Placental tissues were obtained from 25 pregnant women and 21 cases of gestational trophoblastic diseases (10 early complete moles, 3 placental site trophoblastic tumors, 4 invasive moles, and 4 choriocarcinomas). The expression of the 4 ADAMTS was analyzed by immunohistochemistry. Results.-ADAMTS-1, -4, -5, and -14 were differentially expressed by the human placenta throughout gestation in a time-specific and cell type-specific manner, as well as in gestational trophoblastic diseases. ADAMTS-1 showed gradually strong staining intensity in gestational trophoblastic diseases according to the invasive potential but showed consistent strong intensity throughout normal placenta. ADAMTS-4 and ADAMTS-5 exhibited higher and restricted expression in first-trimester intermediate trophoblasts. They also exhibited comparably strong expression in gestational trophoblastic diseases. However, ADAMTS-14 expression remained unchanged throughout gestation. Conclusions.-The restricted expression pattern of ADAMTS-4 and ADAMTS-5 and their increased expression in gestational trophoblastic diseases suggest that these 2 ADAMTS subtypes are associated with a biological phenotype of trophoblasts involved in human placentation and the development of gestational trophoblastic diseases.Archives of pathology & laboratory medicine 05/2014; 138(5):643-650. DOI:10.5858/arpa.2012-0227-OA · 2.88 Impact Factor
Article: High Concordance of Gene Expression Profiling-correlated Immunohistochemistry Algorithms in Diffuse Large B-cell Lymphoma, Not Otherwise Specified.[Show abstract] [Hide abstract]
ABSTRACT: Diffuse large B-cell lymphoma (DLBCL) is classified into prognostically distinct germinal center B-cell (GCB) and activated B-cell subtypes by gene expression profiling (GEP). Recent reports suggest the role of GEP subtypes in targeted therapy. Immunohistochemistry (IHC) algorithms have been proposed as surrogates of GEP, but their utility remains controversial. Using microarray, we examined the concordance of 4 GEP-correlated and 2 non-GEP-correlated IHC algorithms in 381 DLBCLs, not otherwise specified. Subtypes and variants of DLBCL were excluded to minimize the possible confounding effect on prognosis and phenotype. Survival was analyzed in 138 cyclophosphamide, adriamycin, vincristine, and prednisone (CHOP)-treated and 147 rituximab plus CHOP (R-CHOP)-treated patients. Of the GEP-correlated algorithms, high concordance was observed among Hans, Choi, and Visco-Young algorithms (total concordance, 87.1%; κ score: 0.726 to 0.889), whereas Tally algorithm exhibited slightly lower concordance (total concordance 77.4%; κ score: 0.502 to 0.643). Two non-GEP-correlated algorithms (Muris and Nyman) exhibited poor concordance. Compared with the Western data, incidence of the non-GCB subtype was higher in all algorithms. Univariate analysis showed prognostic significance for Hans, Choi, and Visco-Young algorithms and BCL6, GCET1, LMO2, and BCL2 in CHOP-treated patients. On multivariate analysis, Hans algorithm retained its prognostic significance. By contrast, neither the algorithms nor individual antigens predicted survival in R-CHOP treatment. The high concordance among GEP-correlated algorithms suggests their usefulness as reliable discriminators of molecular subtype in DLBCL, not otherwise specified. Our study also indicates that prognostic significance of IHC algorithms may be limited in R-CHOP-treated Asian patients because of the predominance of the non-GCB type.The American journal of surgical pathology 04/2014; DOI:10.1097/PAS.0000000000000211 · 4.59 Impact Factor
Article: Characteristics of Cutaneous Lymphomas in Korea According to the New WHO-EORTC Classification: Report of a Nationwide Study.[Show abstract] [Hide abstract]
ABSTRACT: Previously, cutaneous lymphomas were classified according to either the European Organization for the Research and Treatment of Cancer (EORTC) or the World Health Organization (WHO) classification paradigms. The aim of this study was to determine the relative frequency of Korean cutaneous lymphoma according to the new WHO-EORTC classification system.The Korean Journal of Pathology 04/2014; 48(2):126-32. DOI:10.4132/KoreanJPathol.2014.48.2.126 · 0.17 Impact Factor
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ABSTRACT: LGALS3, a member of the lectin family, has an important role in tumor progression through inhibition of apoptosis. LGALS3 shares several significant structural properties with BCL2. In this study, we examined the prognostic significance of LGALS3 and BCL2 in uniformly treated classical Hodgkin's lymphoma. Diagnostic tissues from 110 patients with uniformly treated classical Hodgkin's lymphoma were evaluated retrospectively by immunohistochemical analysis of LGALS3 and BCL2 expression. The median follow-up time was 6.2 years (range, 0.2-17.3 years). Twenty-seven patients (25%) expressed LGALS3 protein in Hodgkin/Reed-Sternberg cells, which was associated with poor overall survival and event-free survival (P=0.007 and P<0.001). Fifteen patients (14%) expressed BCL2 protein in Hodgkin/Reed-Sternberg cells, which was not associated with overall survival and event-free survival (P=0.928 and P=0.900).There was no correlation between LGALS3 and BCL2 expression (P=0.193). Multivariate analysis identified LGALS3 protein as an independent prognostic factor for event-free survival (P=0.007). Subgroup analysis according to the Ann Arbor stage of classical Hodgkin's lymphoma showed that LGALS3 protein expression had a prognostic value in limited-stage classical Hodgkin's lymphoma (P<0.001). The results of this study suggest that LGALS3 is an independent prognostic factor in classical Hodgkin's lymphoma, and may allow the identification of a subgroup of patients with limited-stage classical Hodgkin's lymphoma who require more intensive therapy.Modern Pathology advance online publication, 7 March 2014; doi:10.1038/modpathol.2014.38.Modern Pathology 03/2014; 27(10). DOI:10.1038/modpathol.2014.38 · 6.36 Impact Factor
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ABSTRACT: Primary mediastinal large B-cell lymphoma (PMBL) is a distinct subtype of non-Hodgkin lymphoma, which has no consensus for its ideal treatment or prognosis. We reviewed the clinicopathologic features and clinical outcomes of 25 PMBL cases diagnosed at a single institution between 1993 and 2009 and compared them with 588 cases of non-mediastinal, diffuse large B-cell lymphoma (DLBCL, control group) diagnosed during the same period. Thirteen (52.0%) PMBL patients had Ann Arbor stage III or IV disease, and 10 (40.0%) had B symptoms. Thirteen (52%) PMBL patients were classified as high-intermediate/high-risk according to the International Prognostic Index. There was a significant prevalence of young (median: 31 years; range, 15-78 years; P<0.001), female (68%; P=0.014) patients in the PMBL group compared to the control group (median: 56 years; range, 15-85 years; 43.2% female). Bulky disease and elevated levels of lactate dehydrogenase (LDH) were more frequent in the PMBL group (P<0.001 and P=0.003, respectively). Nineteen (76%) PBML patients achieved complete remission, and 18 were alive at the last follow-up (median: 43 months; range, 1-92 months). There was no difference in the 3-year, overall survival rate (72%, 95% confidence interval [CI]: 54.0-83.0 versus 70.1%, 95% CI, 109.0-126.0; P=0.686) between PMBL and control patients, respectively. Compared to patients with non-mediastinal DLBCL, Korean patients with PMBL are predominantly young women with bulky disease and high LDH levels but with no significant difference in survival.03/2014; 49(1):36-41. DOI:10.5045/br.2014.49.1.36
Article: CD163 Expression Was Associated with Angiogenesis and Shortened Survival in Patients with Uniformly Treated Classical Hodgkin Lymphoma.[Show abstract] [Hide abstract]
ABSTRACT: Recent studies have reported the prognostic value of tissue-associated magrophages (TAMs) in classical Hodgkin lymphoma (cHL). In addition, TAMs are implicated in the tumor angiogenesis. In this study, we examined the prognostic relevance of TAMs in relation to vascular endothelial growth factor (VEGF) expression and angiogenesis in uniformly treated cases of cHL. Diagnostic tissue from 116 patients with ABVD-treated cHL was evaluated retrospectively by immunohistochemical analysis for CD68, CD163 and VEGF expression and for CD31 expression as a measure of microvessel density (MVD). High CD163 expression (≥35% of cellularity) correlated with VEGF expression (Pearson's Chi-square test, P = 0.008) and MVD (Spearman correlation coefficient 0.310, P<0.001). High CD163 expression was associated with inferior event-free survival (EFS, P = 0.005) and overall survival (OS, P<0.001) in univariate analysis. In multivariate analysis, high CD163 expression was strongly associated with inferior EFS (P = 0.043) and OS (P = 0.008). Patients with high MVD had a lower OS than those with low MVD, but the difference was not significant (P = 0.071, respectively). While high expression of CD68 was also associated with inferior EFS (P = 0.007), it showed no correlation with VEGF or MVD. Our data confirms that CD163 expression provides independent prognostic information in cHL. The correlation of CD163 with VEGF expression and MVD suggests the role of CD163-positive cells in tumor angiogenesis of cHL.PLoS ONE 01/2014; 9(1):e87066. DOI:10.1371/journal.pone.0087066 · 3.53 Impact Factor
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ABSTRACT: The gastrointestinal tract is the most common primary extranodal site for diffuse large B-cell lymphoma (DLBCL). However, there is no consensus on the most appropriate staging system for intestinal DLBCL. We evaluated the utility of the modified Ann Arbor system, the Lugano system, and the Paris staging system (a modification of the Tumor, Node, Metastases [TNM] staging for epithelial tumors) in 66 cases of resected intestinal DLBCL. The cases were treated with surgery, plus either cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) chemotherapy alone (n=26) or with the addition of rituximab immunotherapy (n=40). Median follow-up time was 40.4 months (range, 2.1-171.6 months). Fifty-six patients (84.8%) achieved complete remission. The overall 5-yr survival rate was 86.4% (57/66). Of the stage categories defined for each staging system, only the T stage of the Paris classification showed prognostic significance for overall survival by univariate analysis. However, none of the stage parameters was significantly correlated with patient survival on multivariate analysis. In conclusion, the results suggest that the T stage of the Paris classification system may be a prognostic indicator in intestinal DLBCL. The results also imply that in surgically resected intestinal DLBCL, the addition of rituximab to the CHOP regimen does not confer significant survival advantage.Journal of Korean medical science 01/2014; 29(1):53-60. DOI:10.3346/jkms.2014.29.1.53 · 0.84 Impact FactorThis article is viewable in ResearchGate's enriched formatRG Format enables you to read in context with side-by-side figures, citations, and feedback from experts in your field.
Article: Prognostic Significance of Absolute Lymphocyte Count/Absolute Monocyte Count Ratio at Diagnosis in Patients with Multiple Myeloma[Show abstract] [Hide abstract]
ABSTRACT: Absolute lymphocyte count (ALC) in peripheral blood has recently been reported to be an independent prognostic factor in multiple myeloma (MM). Previous studies indicated that the absolute monocyte count (AMC) in peripheral blood reflects the state of the tumor microenvironment in lymphomas. Neither the utility of the AMC nor its relationship with ALC has been studied in MM. The prognostic value of ALC, AMC, and the ALC/AMC ratio at the time of diagnosis was retrospectively examined in 189 patients with MM. On univariate analysis, low ALC (<1,400 cells/µL), high AMC (≥490 cells/µL), and low ALC/AMC ratio (<2.9) were correlated with worse overall survival (OS) (p=.002, p=.038, and p=.001, respectively). On multivariate analysis, the ALC/AMC ratio was an independent prognostic factor (p=.047), whereas ALC and AMC were no longer statistical significant. Low ALC, high AMC, and low ALC/AMC ratio were associated with poor prognostic factors such as high International Staging System stage, plasmablastic morphology, hypoalbuminemia, and high β2-microglobulin. Univariate analysis demonstrated that changes in ALC, AMC, and the ALC/AMC ratio are associated with patient survival in MM. Multivariate analysis showed that, of these factors, the ALC/AMC ratio was an independent prognostic factor for OS.The Korean Journal of Pathology 12/2013; 47(6):526-33. DOI:10.4132/KoreanJPathol.2013.47.6.526 · 0.17 Impact FactorThis article is viewable in ResearchGate's enriched formatRG Format enables you to read in context with side-by-side figures, citations, and feedback from experts in your field.
Article: Prognostic value of immunohistochemical algorithms in gastrointestinal diffuse large B-cell lymphoma[Show abstract] [Hide abstract]
ABSTRACT: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous clinicopathological entity, and its molecular classification into germinal center B cell-like (GCB) and activated B cell-like (ABC) subtypes using gene expression profile analysis has been shown to have prognostic significance. Recent attempts have been made to find an association between immunohistochemical findings and molecular subgroup, although the clinical utility of immunohistochemical classification remains uncertain. The clinicopathological features and follow-up data of 68 cases of surgically resected gastrointestinal DLBCL were analyzed. Using the immunohistochemical findings on tissue microarray, the cases were categorized into GCB and non-GCB subtypes according to the algorithms proposed by Hans, Muris, Choi, and Tally. The median patient age was 56 years (range, 26-77 years). Of the 68 cases included, 39.7% (27/68) involved the stomach, and 60.3% (41/68) involved the intestines. The GCB and non-GCB groups sorted according to Hans, Choi, and Tally algorithms, but not the Muris algorithm, were closely concordant (Hans vs. Choi, κ=0.775, P<0.001; Hans vs. Tally, κ=0.724, P<0.001; Choi vs. Tally, κ=0.528, P<0.001). However, there was no prognostic difference between the GCB and non-GCB subtypes, regardless of the algorithm used. On univariate survival analyses, international prognostic index risk group and depth of tumor invasion both had prognostic significance. The Hans, Choi, and Tally algorithms might represent identical DLBCL subgroups, but this grouping did not correlate with prognosis. Further studies may delineate the association between immunohistochemical subgroups and prognosis.12/2013; 48(4):266-73. DOI:10.5045/br.2013.48.4.266
Article: Differences in intravascular ultrasound and histological findings in culprit coronary plaques between ST-segment elevation myocardial infarction and stable angina.[Show abstract] [Hide abstract]
ABSTRACT: A comprehensive evaluation of culprit coronary lesions may help to understand vulnerable plaques responsible for ST-segment elevation myocardial infarction (STEMI). We compared intravascular ultrasound (IVUS) and histological findings in culprit coronary plaques from 94 patients with STEMI (n = 54) or stable angina (n = 40). Tissue specimens were obtained by directional coronary atherectomy and IVUS was performed before percutaneous coronary intervention. IVUS and histological data were analyzed. Clinical characteristics were largely similar between the two groups. Plaque rupture and thrombi were more frequently found in the STEMI group than in the stable angina group. There were no significant differences between plaque types or proximal and distal reference measurements in the two groups. However, the site of minimal lumen area had a greater vessel area, remodeling index, and plaque burden with lesser lumen area in the STEMI group than in the stable angina group. Plaque areas immunopositive for CD68 and CD31 were significantly larger in the STEMI group, while the area immunopositive for α-smooth muscle actin was larger in the stable angina group. In conclusion, culprit lesions in STEMI patients showed a greater plaque burden, remodeling index, and more frequent thrombi with increased inflammation and neovascularization compared to the stable angina group, supporting the current concept of vulnerable plaques being responsible for STEMI.Journal of Thrombosis and Thrombolysis 09/2013; DOI:10.1007/s11239-013-0975-z · 1.99 Impact Factor
Article: Clinical significance of the appearance of abnormal protein band in patients with multiple myeloma[Show abstract] [Hide abstract]
ABSTRACT: Multiple myeloma (MM) is characterized by clonal expansion of malignant bone marrow cells producing a unique monoclonal immunoglobulin. The appearance of abnormal protein band (APB) in MM has been reported during follow-up. We aimed to evaluate the clinical characteristics and outcomes of patients with APB in a single center cohort. A total of 377 consecutive MM patients were treated at the Asan Medical Center between January 2002 and December 2012. We compared clinical characteristics and survival outcome between those with and without APB. Of the 377 patients, 34 (9 %) experienced APB. They comprised 18.2 % (27/148) of patients treated with autologous stem cell transplantation (ASCT) and 3.1 % (7/229) of those not receiving ASCT. APB occurred after a median of 7.9 months (range, 2.2-95.7 months) from diagnosis. Immunoglobulin isotypes at diagnosis were as follows: IgG (n = 10), IgA (n = 8), IgD (n = 5), free κ (n = 4), and free λ (n = 7). Nine patients experienced a second APB. With a median follow-up of 54.1 months, the median overall survival (OS) has not been reached in patients with APB and was 38.3 months in patients without (P < 0.001). Multivariate analysis indicated that the development of APB was a significant favorable prognostic factor for OS (hazard ratio 0.21; 95 % confidence interval 0.08-0.52). Serum β2-microglobulin, albumin, creatinine, and ASCT were also independent prognostic factors for OS. Further investigation is required to establish the mechanisms underlying APB in MM.Annals of Hematology 09/2013; 93(3). DOI:10.1007/s00277-013-1890-2 · 2.40 Impact Factor
Top Journals
University of Ulsan
Urusan, Ulsan, South Korea
- • College of Medicine
- • Department of Medicine
Asan Medical Center
Sŏul, Seoul, South Korea
- • Department of Pathology
- • Department of Cardiology
Ulsan University HospitalUrusan, Ulsan, South Korea
Seoul National University Hospital
Sŏul, Seoul, South Korea
- Department of Ophthalmology


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text: immigration Michigan lawmakers look to address immigration issues at state level By Jake Neher • Apr 24, 2013 Steve Carmody/Michigan Radio State officials are weighing in on the immigration debate. Democrats in the state House Tuesday introduced a package of bills to change the way the Michigan treats immigrants. Under the legislation, the state would offer in-state college tuition to some undocumented students. It would also create an office to coordinate resources and services for people hoping to become U-S citizens. Representative Jeff Irwin says the legislation includes language he thinks Republican leaders in Lansing could support. The week in Michigan politics: dredging, immigration and right to work By Jack Lessenberry, Christina Shockley & Emily Fox • Apr 24, 2013 cncphotos / flickr Listen Listening... / 4:35 The week in Michigan politics interview This week in Michigan politics, Christina Shockley and Jack Lessenberry discuss the issue of dredging in Michigan's harbors, a package of bills that would make Michigan a more immigrant-friendly state, and how lawmakers have backed off from punishing colleges and municipalities for negotiating contracts before the right to work law went into effect. In this morning's news: right-to-work penalties dropped, immigration reform bills, Michigan budget By Michigan Radio Newsroom • Apr 24, 2013 User: Brother O'Mara / flickr House Republicans won't push right-to-work penalties "State House Republicans have given up on efforts to punish school districts and other public employers that agreed to labor contracts that delayed the effects of Michigan's right-to-work law. The House GOP majority allowed budget bills to move forward without threatened reductions in state payments," Rick Pluta reports.Democrats introduce legislation for immigration reform"Yesterday, state House Democrats introduced a package of bills they say would make Michigan a more immigrant-friendly state. Among other things, the legislation would provide in-state college tuition for some undocumented students and create an office to coordinate services and resources for immigrants," according to Jake Neher.Lawmakers move forward in passing state budget"The Republican-controlled House today is planning to approve its entire spending plan for state government along with schools and colleges. The GOP-led Senate is expected to OK about half of its budget plant, and follow with the rest later. The moves will set the stage for negotiations in May with a goal of finishing up by June," the Associated Press reports. The week in review: lowering auto insurance, drug testing the poor, immigration protests By Jack Lessenberry & Rina Miller • Apr 20, 2013 Steve Carmody/Michigan Radio Listen Listening... / 2:54 Week in review interview for 4/19/13 This week in review, Rina Miller and Jack Lessenberry discuss the possible plan to lower auto insurance rates in the state, a bill to require drug tests for welfare recipients, and the arrests made at the University of Michigan over immigration protests. Stateside for Wednesday, April 17th, 2013 By Stateside Staff • Apr 17, 2013 On today's show: we continue our look at road-funding Michigan. There's a new proposal out this week in the state House that would shift the way we pay for road and bridge repairs, but can it really pass with both Democratic and Republican support? Governer Snyder's take on Immigration reform By Stateside Staff • Apr 17, 2013 Steve Carmody / Michigan Radio Listen Listening... / 10:54 The so-called gang of eight have released their immigration reform proposal. The formal introduction of the bipartisan bill known as the "Border Security, Economic Opportunity and Immigration Modernization Act of 2013" was filed last night at 2 a.m. The 844 piece of legislation would enact sweeping changes to the nation's immigration laws. President Obama says the bill is a compromise that doesn't give everyone everything they want, but he's urging the Senate to move forward with it. So we took a look at the man who likes to call himself the nation's most pro-immigration Governor - Gov. Rick Snyder. Rick Pluta Lansing Bureau Chief for the Michigan Public Radio Network was with the Governor this afternoon and tells us what he had to say about the introduction of this bill. Listen to the full interview above. Stateside for Thursday, March 21, 2013 By Stateside Staff • Mar 21, 2013 Listen Listening... / 46:12 Millions of undocumented immigrants in this country are hoping this is the year for immigration reform. On today's show, we explore what the future holds for mixed-status families. And, it's being called "one of the most dramatic ecological recovery stories in North America." Why beavers along the Detroit River are such a big deal.And, it's been a week now since Governor Snyder announced Kevyn Orr as Detroit's emergency manager, and it was a week ago that we last spoke with Daniel Howes, business columnist at the Detroit News. We checked in with Howes about the prospect of a Detroit recovery. All that, and roller derbies and march madness, on today's show. Stateside: Immigration issues in Michigan By Stateside Staff • Feb 4, 2013 U.S. ICE Listen Listening... / 17:58 The following is a summary of a previously recorded interview. To hear the complete segment, click the audio above. For the very first time in more years than just about anyone can remember, things seem to be lining up in favor of immigration reform. Stateside: Children of undocumented immigrants eligible for Michigan IDs or driver's licenses By Stateside Staff • Feb 4, 2013 Michigan Sheriffs' Association Listen Listening... / 4:38 The following is a summary of a previously recorded interview. To hear the complete segment, click the audio above. There has been a change of heart, or at least of policy, at Michigan's Secretary of State's office. Word came down late last week that thousands of children of undocumented immigrants in Michigan will now be eligible for a driver's license or official state ID. This was quite a reversal of the stand that had been taken by Michigan Secretary of State Ruth Johnson who now says a review of new federal guidelines convinced her to change the policy. Cyndy spoke with Miriam Aukerman, staff attorney with the ACLU of Michigan, to talk about the change of policy. As immigration plans emerge, Michigan activists plan for march on Washington By Sarah Cwiek • Jan 28, 2013 Sarah Cwiek / Michigan Radio President Obama and federal lawmakers are announcing new plans for major immigration reform this week. That comes as activists from Michigan and around the country are preparing for a major immigrant rights march in Washington, D.C. this spring. There are an estimated 11 million people living in the U.S. illegally, and an estimated 100,000 in Michigan. Advocates hope to send at least 250 affected families from across the state to the "Keep Families Together" march on April 10th. Congressman Gary Peters, a Democrat representing Detroit and much of Oakland County, says he's hopeful that event can capitalize on growing public pressure for immigration reform. "I think if most Americans can hear these compelling stories of people trapped in a dysfunctional immigration system, and the types of problems it's created for their families…the American people will notbelieve that's an acceptable system," Peters said. Peters says he's "cautiously optimistic" that real immigration reform is possible, despite likely fierce opposition in the Republican-dominated U.S. House. A bipartisan group of Senators and President Obama are releasing frameworks for such reform this week. Immigration reform advocates are cautiously hailing the Senate framework on some key points. They're happy it includes a so-called "earned path to citizenship" for those now in the country illegally. Detroit resident Cindy Garcia will attend the April march with her family. She's fought successfully to prevent her husband, an undocumented immigrant from Mexico, from being deported. "Because if I can do it for myself, and my family, I can do it for the eleven other million families. Because when I stand here and tell my story, it's not just for me," Garcia said. "I have to think of other children being separated from their families, and it's not fair." Michigan Secretary of State sued for denying driver's licenses to undocumented immigrants By Michigan Radio Newsroom • Dec 19, 2012 Michigan Sheriffs' Association The ACLU of Michigan is suing Secretary of State Ruth Johnson over her decision to deny driver's licenses to undocumented immigrants with work permits granted under a new federal-deferred action plan. The suit was brought on behalf of three young immigrants and One Michigan, a youth-led advocacy group. There are approximately 15,000 young people in Michigan who are eligible for the federal program. More protests at Secretary of State related to "Deferred Action for Childhood Arrivals" program By Lindsey Smith • Oct 26, 2012 Wendy Medrano / Michigan Organizing Project More people are protesting against a decision to deny Michigan driver's licenses to immigrants granted work permits under a new federal deferred-action program. President Obama announced the "Deferred Action for Childhood Arrivals" program in June. It provides work permits and Social Security cards to young people brought to the United States without legal permission. But Michigan Secretary of State Ruth Johnson will not issue those in the program driver's licenses because she says they don't have legal status. Immigration and the Latino vote By Jennifer White & Mercedes Mejia • Oct 23, 2012 Flickr/jnn1776 Recently, there was a protest rally in Southwest Detroit against Immigration and Customs Enforcement over raids and deportation, and what's seen as overreach by ICE officials. Non-citizens can't legally vote, but how does the heightened sense of tension impact the Latino vote here in Michigan? Also, the Latino community is one of the fastest growing minority groups in the state. Should there be more Latino representation among lawmakers? Jennifer White talks with Laurence Garcia, an attorney, and the Chairman of the Hispanic Latino Commission of Michigan. Kalamazoo non-profit tries to help answer questions about deferred deportation option By Lindsey Smith • Aug 24, 2012 A non-profit organization in Kalamazoo is trying to help young undocumented immigrants sort through a new federal process that could prevent them from getting deported. The director of the US Citizenship and Immigration Services announced the process earlier this month. Lori Mercedes is the Executive Director of the Kalamazoo-based Hispanic American Council. She says many immigrants have been calling with questions about the process but are nervous about exposing their legal status. "This brought it up to the light and forced a conversation about it. It made it into an issue; now we have to talk about it," Mercedes said. "It's exciting…we can tell our kids go ahead and dream and have hope. There is hope for you after all." "DREAMers" gain protections under new immigration policy By Sarah Cwiek • Aug 15, 2012 Sarah Cwiek / Michigan Radio Immigrant advocates are celebrating a new policy that offers some protections for young immigrants. And a few of them wasted no time heading to US immigration offices in Detroit on Wednesday, the first day applications became available. The new Obama administration policy is the so-called the DREAM Relief Program—or, more formally, the "Deferred Action Enforcement Process for Young People Who Are Low Enforcement Priorities." Legal help for Syrian nationals with expiring visas By Kate Wells • Jul 16, 2012 Kate Wells / michiganradio.org For a few hours Saturday morning, the Troy Public Library became Syrian immigration base camp. Some two dozen Syrian nationals came out to a makeshift legal clinic held there. Their visas are about to expire or already have, and the federal government's offering a special extension due to the crisis in their country. But as pro-bono lawyers explained to one family after another, Syrians who fled escalating violence in the last three months aren't eligible; they've already missed the program's crucial window. That window ended March 29, when the Obama administration declared Syrians in the United States could receive Temporary Protected Status, or TPS. That lets Syrians stay here even after their visas expire. Presidential candidate Mitt Romney finishes small town tour in Holland By Lindsey Smith • Jun 20, 2012 Lindsey Smith / Michigan Radio "This is a defining time for this country. That's a place where the president and I agree," the Republican Presidential candidate said in Holland Tuesday night. Thousands of Romney supporters in shorts and sandals rallied on the shore of Lake Michigan at Holland State Park. Romney's 20-minute long speech focused on how important a strong American economy and military are to the rest of the world. "American strength is the best ally peace has ever known. We must strike for a strong America," Romney said. Romney says the president's health care overhaul is hurting small businesses. He says the economy is being dragged down by uncertainty about the federal debt. He says he worries that the United States is headed on the same path as Greece. Obama immigration policy change gets mixed review in Michigan By Steve Carmody • Jun 15, 2012 Steve Carmody/Michigan Radio A major change in U.S. immigration policy is getting a mixed reaction from advocates for undocumented immigrants in Michigan. Dearborn immigration town hall tries to bridge gap between law enforcement, public By Sarah Cwiek • May 18, 2012 Top federal law enforcement officials took questions on immigration laws at a Dearborn town hall Thursday night. Organizers say the event was meant to break down barriers between law enforcement and the public on a particularly complex and emotional topic: immigration. Special Agent in Charge Brian Moskowitz from the Department of Immigration and Customs Enforcement (ICE), Detroit ICE field office director Rebecca Adducci, and U.S. Citizenship and Immigration Services Detroit office director Mick Dedvukaj fielded questions on a range of topics. Immigrant memoir project By Kyle Norris • May 4, 2012 Kyle Norris Seven years ago, political science professor Ron Stockton was mentoring a student from Poland who was struggling with a writing assignment. So Stockton told her to imagine she was writing a letter to her great-grandchildren describing her life here as an immigrant. The student loved the idea, got super excited, and spread the word about Stockton's technique. Pages« first ‹ previous 1 2 3 4 5 6 next › last »


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Hot Deals For Your Wheels
63 NE 5th
Madras, OR 97741
|MON 8:00am - 6:00pm
|TUE 8:00am - 6:00pm
|WED 8:00am - 6:00pm
|THURS 8:00am - 6:00pm
|FRI 8:00am - 6:00pm
|SAT 8:00am - 5:00pm
|SUN closed
Welcome to Chappy's Auto Parts! We are an Auto Value Parts Store serving the Madras area. Whether you are looking for parts for your car, truck, 4 WD or performance vehicle, you have come to the right place. We offer excellent customer service along with discount prices.
Come by and visit us today!
Category: Auto Parts
EXCELLENT Customer Service! by Caravandude - 06/09/2013
There are a few places to get auto parts in Madras, I've tried them. I stood for nearly 20 min at another store while the clerk talked about farm work with his buddy. HE rolled his eyes at me when I interrupted to ask about a brake booster.I went to Chappy's and they gave quick, NICE service and even offered some pointers on how to fix my rig.The part that I ordered was less expensive than at the eye-rolling place - they're never going to see another dime from me again.I'm a big fan of Chappy's now and would highly recommend them.
BEST PRICES & BEST CUSTOMER SERVICE by Lynn - 07/05/2009
Serving: Madras OR
Product: Transmission Parts, Brake Parts, Auto Electrical Parts, Car Engines, Fuel System Parts, Sunroofs, Auto Supplies, Auto Air Conditioning Parts, Auto Body Parts
Specialty: Domestic Auto Parts, Performance Auto Parts, 4WD Parts
Buying Options: Wholesale Auto Parts
Convenience: Emergency Service
Payment Options: Debit Cards, Visa, Mastercard, American Express, Discover
Assurances: Licensed
Products: 3M, AC Delco, Ball Joints, Bearings, Bed Liners, Blue Streak, Bras, Bug Shields, Cables, Cam Bearings, Camshafts, Castrol, Chains, Charging Systems, Coils, Cruise Control, CV Joints, Drums, Electrical Systems, Fenderskirts, Filters, Flywheels, Gaskets, Gates, Gauges, Gearboxes, Grill Guards, Hammers, Heating Systems, Hitches, Hood Protectors, Jacks, Joints, Lift Kits, Lighting Systems, Mounts, Overload Springs, Parts Master, Pennzoil, Power Train, Pro Comp, Pumps, Quaker State, Relays, Royal Purple, Seals, Sensors, Skyjacker, Spoilers, Springs, Stant, Superchips, Support Systems, SUVs, Switches, Truck-Lite, Valvoline, Wings, Wiper Blades
Services: Maintenance, Testing
Brands: Accord, Cavalier, Century, Concorde, Corvette, Crown Victoria, Escalade, Expedition, Explorer, Five Hundred, Free Lander, Grand Am, Grand Caravan, Grand Marquis, Impala, Impreza, Lancer, LeSabre, Lucerne, Mazda3, Mazda5, Mazda6, Mondial Coupe, Monte Carlo, Mountaineer, Regal, RELAY, Rendezvous, Seville, Sienna, Sierra Classic, Spider, Suburban, Tacoma, Tahoe, Taurus, Terios, Thunderbird, Town & Country, Town Car, Trailblazer, Wrangler, Wrangler Unlimited, Yukon Denali
Details: Assurances: Over 30 Years Experience, Assurances: Over 5 Years Experience, Service Options: 1 Day Service, Service Options: 1 Hour Service, Service Options: 2 Hour Service, Service Options: Same Day Service, Vehicle Features: 4 Cylinder, Vehicle Features: 4WD, Vehicle Features: 6 Cylinder, Vehicle Features: 8 Cylinder, Vehicle Features: Automatic, Vehicle Features: Moon Roofs, Vehicle Features: Power Steering, Vehicle Type: Imports
DexKnows Mobile profile for Chappy's Auto Parts in Madras, OR


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Since 1928 Torrence Sound Equipment Co. has been dedicated to providing sound, video, and security system solutions to our customers throughout Northwest Ohio and Southeast Michigan. Torrence Sound specializes in systems for Healthcare, Education, Commercial, Industrial and Worship applications.
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1:4 RF Distribution Amplifier
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The 104R is a high-performance distribution amplifier for RF signals. It takes one RF (CATV/MATV) signal and distributes it to four identical outputs.
High Bandwidth - 3000MHz.
RF Gain - + 6dB across band.
Compact Size - Part of the Kramer TOOLS™ family of compact, high quality and cost effective solutions.
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2.95 in
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4.70 in
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Depth :
74.93 mm
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24.89 mm
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119.38 mm
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0.32 kg
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12 Volts
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1 RF, 0.5Vpp/75 ohm(max.) on an ¡°F¡ type connector.
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4 RF, 0.5Vpp/75 ohm(max.) on ¡°F¡ type connectors.
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RF Gain :
+6dB typical across band.
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12VDC Power supply, mounting bracket.
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RK-T3, RK-T1 Rack Adapters
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text:
Favorite Gourd Projects?
I have a bunch of birdhouse gourds and need some gourd project ideas? Thanks!
All I have ever done with gourds is paint them. I'll post a couple pics for you to see. I also have a snowman and have started a Santa but never finished him yet.
I've seen some great looking birdhouses made from them too.
I didn't know we had a gourd forum on here, will have to check that out sometime too. Luvs
I occasionally paint a gourd or two. Mine usually look like houses, but I've done a few banks, too, sometimes combining the two.
This is one of the beach house our friends have in FL. It commemorates our first vacation there with them. There's a hidden door where the flamingo is. There's a wire glued to the inside of the door that has a loop on the end. The loop fits thru a small slot on the opposite side of the gourd and locking it in place is a miniature green hose coiled up.
This next one is a bank. In between the luna moths is a door that pops out. A piece of grapevine locks it closed.
Been off the computer for awhile ( only way to get my yard work done) sure am glad I didnt miss this post, luvs, your grouds are sooo cute! what a beautiful job you have done.
Sandra, I so love your red bowel, you have some real beautiful grouds on your site, the name says it all!
flamingo , love your grouds, you are so creative, beautiful job!
where can I find the groud fourm? I have tried searching but can not seem to find it.


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Everett Golson no longer enrolled at Notre Dame
Notre Dame announced Saturday that starting quarterback Everett Golson is no longer enrolled at the school, leaving the Irish without their emerging star and leader. Golson helped lead the Irish to the 2013 BCS championship game in a season that wasn't short on highlights.
Irish lose starting quarterback Everett Golson | Were academics reason for Golson's departure? | Could Gunner Kiel return to Notre Dame?
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Wallet 2015: Buying in on Michael Brantley, Jose Altuve, Jimmy Rollins
Many drafts, many common-link batters for Pianow. Michael Brantley leads things off.Roto Arcade
RADIO: Why Duke vs. Kentucky is not a slam dunk
Yahoo! Sports's Pat Forde, joins Matt Perrault to explain why it's not a lock to pick Duke or Kentucky to win the NCAA Tournament.Yahoo Sports Radio
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Top Things You Should Know About Dental Implants
Considering dental implants? Read these articles and learn about procedures, options, costs and providers before making this important decision.
Andrew Wiggins dunks on Rudy Gobert twice, fears no man
The Stifle Tower got his revenge on Wiggins just a few seconds after the second slam.Ball Don't Lie
Venus Williams beats Wozniacki to reach Miami Open quarters
Basking in her latest victory, a beaming Venus Williams stood near her changeover chair launching autographed balls into the stands, steering her shots with body English and applauding the fans who scrambled for the souvenirs. She's 34 but on the rise in the rankings, and she beat former No. 1…The Associated Press
Hamilton ready to sign on the dotted line
Formula One world champion Lewis Hamilton is ready to sign a new contract that, according to media reports, could net him more than $40 million a year. There's no reason why it shouldn't be," the Mercedes driver told British reporters after finishing second in Sunday's Malaysian Grand Prix.Reuters