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This is the third module in the Solar Dynamic Observatory (SDO) Project Suite curriculum. Each activity is self-directed by students or student teams and utilizes online videos, data from the SDO satellite and hands-on activities to explore,... (View More) research and build knowledge about how the Sun's varying activity impacts Earth and space weather. Each activity provides opportunities to build knowledge and vocabulary, apply or demonstrate learning through real world connections and create resources to use in investigations. Both a teacher and student guide are included with sequential instructions and embedded links to the needed videos, tutorials and internet resources. In Activity 3A: Sun-Earth Interactions, students gather information from online videos and create a 3D model to demonstrate the relationship to Earth's place in space and the affect of Earth's axial tilt on our seasons, then film a short video explaining the reasons for the seasons. Activity 3B: Space Weather, students use online videos to gather information on what space weather is, and its causes and effects, to create a concept map. They then use real-time real-time SDO data to forecast space weather. Activity 3C: Solar Research in Action! Make a Magnetometer has students view information in online videos about to Earth's magnetosphere and the impacts of space weather, then create a magnetometer to detect and visualize changes in the Earth's magnetic fields to monitor solar storm impacts. A computer for student-teams and access to the internet are needed for this module. (View Less)
Materials Cost: $5 - $10 per group of students
This is a lesson about the energy output of the Sun. Learners will consider the essential question, "How much energy does sunlight provide to the Earth and what is its role in the Earth's energy resources?" Activities include building a device to... (View More) measure the solar constant - the amount of energy in sunlight - calculating the amount of energy arriving at the Earth from the Sun, and describing the differences in solar radiation at Mercury compared to Earth. This is activity 1 of 4 in the module, Staying Cool. Note: the student guide starts on p. 21 of the PDF. (View Less)
Materials Cost: $1 - $5 per group of students
This is a lesson about infrared radiation. Learners will investigate invisible forms of light as they conduct William Herschel's experiment and subsequent discovery of infrared radiation. They will construct a device to measure the presence of... (View More) infrared radiation in sunlight, explain that visible light is only part of the electromagnetic spectrum of radiation emitted by the Sun, follow the path taken by Herschel through scientific discovery, explain why we would want to use infrared radiation to study Mercury and other planets, and explain how excess infrared radiation is a concern for the MESSENGER mission. This is activity 1 of 4 at the Grade 5-8 band of "Staying Cool." (View Less)
Materials Cost: $5 - $10 per group of students


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Thanks for visiting my shop! My artwork has been featured on Hostess with the Mostess, Kara's Party Ideas, Pizzazzerie, Chickabug, The Wise Baby, Ceremony Magazine, and Mingle Magazine, but most importantly, in thousands of real events worldwide! If your event is scheduled for spring/summer 2015, please read my shop policies… read more
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Analog to Digital TV?
As time goes on, I am replacing my analog tv's with Sony XBR tv's. My quest is to get a video picture for recording my wife's daily day time shows. The digital channels are clear, but subject to momentary blackout or partial pixel loss. I do not have cable or satelite service. I have purchased two new dvd recorders that will record the digital channels as well. Okay, so now I have dvd rw recordings with some blackout and pixel loss on our recordings.Is there anything I can do to improve the recordings? Thanks
higher gain antenna or get an amplifier. for BEST reception, get the antenna outside and feed your indoor units from it.
you do not wan tto have multiple splitters at all. if you need 4 feeds to the tvs, get a 4 port splitter instead of piggy backing a splitter off another on. each splitter loses 1/2 signal strength MINIMUM per port. so get one as close to the correct size as possible.


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Deborah Geering
Steven Satterfield releases a cookbook, Diana Fitzgerald's stunning smoked trout, and more bite-sized dining news
The latest stuff to eat and drink in Atlanta
News on Steven Satterfield's first cookbook, "Root to Leaf," Diana Fitzgerald's stunning applewood trout, a great wine pick, and Emory's Oxford College farmRead more
Pasta with broccoli and potato
Call me crazy, but I love a little potato with my pasta. Potato's delicate, buttery flavor is not overwhelmed, but rather enhanced by the pasta—and also adds comforting substance to the dish. The trick is to keep the sauce light, or the else the potato will get lost in the mix. Ingredients 2 tablespoons olive oil 2 tablespoons […]Read more
Four March dining events: Hilton Head Island Wine & Food Festival, Suwanee American Craft Beer Festival, and more
Picks for beer and wine lovers
Get ready to indulge at the Hilton Head Island Wine & Food Festival, Suwanee American Craft Beer Festival, Le Caveau Fine Wines' Champagne dinner, and BaconFestRead more
Winter Vegetable Curry with Cashew Basmati Rice
This quick, 2-pot dinner (1 pan for the curry, 1 pot for the rice) is beautiful and delicious, but it's also versatile. Add, subtract, or substitute vegetables as you wish, just like a stir-fry. Try parsnips, turnips, Brussels sprouts, or even frozen peas or green beans. If you have any doubts about cooking times, just […]Read more
Todd Ginsberg improves the Philly cheesesteak, Pie Local's new owner thrives, and more bite-sized dining news
The latest stuff to eat and drink in Atlanta
Meet the defining sub at Fred's Meat & Bread, Todd Ginsberg's stellar sandwich stall in Krog Street Market. Ginsberg originally planned to serve strictly burgers until he and his partners remembered the Philly cheesesteak.Read more
Four February dining events in Atlanta: Uncorked Atlanta, Taste of Athens, and more
Two picks for wine lovers, plus barbecue and Athens' best
Wine and dine yourself at Uncorked Atlanta, Taste of Athens, Oakhurst's wine crawl, and Atlantic Station's festival of beer, bourbon, and barbecue.Read more
Farmers to 40 coffee far exceeds "fair trade"
The nonprofit, started at Emory's Goizueta Business School, directs up to 40 percent of retail proceeds back to farmers
This coffee isn't just good; it's fair. Farmers to 40, a nonprofit business launched in October 2013 through a social enterprise program at Emory University's Goizueta Business School, directs up to 40 percent of the retail proceeds back to the farmers themselves, an initiative that far exceeds most "fair trade" practices.Read more
Easy Chicken and Mushroom Tacos
Fast weeknight dinners don't have to be dull. If you're willing to dirty two frying pans—one for the chicken, one for the mushrooms and onions–this fun supper comes together in about 20 minutes.Read more
Four January dining events in Atlanta
Enjoy beer samples and a sweet hot chocolate reward
This month, enjoy beer samples and reward yourself with sweet treats.Read more
Fireside Cranberry Toddy
A toddy is a hot, sweetened cocktail—the perfect concoction for winter evenings. This one balances sweetness with tart cranberry juice, which also happens to add some crimson holiday cheer.Read more


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Trivia Night
"Rescue Me" Singles Party
Asian Persuasion
20-Something Night
Gay Speed Dating "Bottoms"
Gay Speed Dating "Tops" Sign-up
One of our most popular events! Meet New York's Most Eligible Firemen.
Cruise around the Hudson with 300 singles. I'm on a boat!
Our exclusive Skinny Minny event where women are hand picked.
Dateline's very own, Chris Hansen, has some fun with our speed daters. Part 2


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Sacramento staffers get raises amid cuts
Boosts for 18 people in San Diego County's delegation total $134,916
"In recognition of these tough economic times I chose to promote from within rather than hire a replacement," Garrick said by email. "Thereby my district staff was reduced from four to three and total district payroll was actually reduced by nearly $29,000."
Statewide, The Sacramento Bee reported this month that 93 legislative employees who make more than $100,000 a year, and another 800 or so earning less, have had raises this year.
Through a spokesman, Assembly Speaker John Perez, D-Los Angeles, said the Assembly has cut its operating budget by 15 percent and diverted that money to other programs to serve veterans and provide child care for the poor.
"These belt-tightening measures have saved $20 million per year and given the Assembly the flexibility to give modest increases to staff who have taken on significant additional responsibilities or whose salaries have been frozen for longer than three years," said John Vigna, Perez's spokesman.


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Hello Tech experts,
When I am trying to play an avi files in Windows media player I ended up with an error message. The error states that I cannot perform the requested action at this time. Do I need to reinstall Windows Media Player? How do I get rid of this error? How I can solve this error? Please help me. Your help is great. Thanks.
Windows Media Player cannot perform the requested action at this time.
- 136 reads
- 1 comment
Hello folks,
I am not a technical person; this error makes me frustrating and I am tired of this error. I am getting an error message when I am trying to play a video from DVD. I tried it play several times, I check the DVD it is perfect and able to play it my laptop. However, why do I get this error in the computer? Do I need to change any setting to support the player? Please help. Thanks.
Windows Media Player cannot play the DVD. The disc was created in a manner that the Player does not support.
- 117 reads
- 1 comment
Hello friends,
When I try to install Realtek in the computer, I stuck with an error window. In fact, the installation went almost to the end, the error triggered only when it tries to install the Audio driver. Therefore, I think the problem is with the drivers. How can I solve this error? Please help me to configure the driver for Realtek. Thanks.
Realtek High Definition Audio Driver- InstallShield Wizard
Install Realtek HD Audio Driver Failure !!
- 264 reads
- 1 comment
Hello Professionals,
The download and the installation of beta version went pretty well and good without any problem. But the problem triggered as soon I start the application, it then immediately closes the program. Is there any system requirement for this? I have windows 2012 operating system. Hunting for solution please help me. Your help isreally great. Thanks.
Application Error
Exception ElnvalidPointer in module BlurayConverterUltimate.exe at
Invalid pointer operation.
- 96 reads
- 1 comment
Hello all,
I have a Sony HDD handy camI bought it last week. When I try to import a video file, I ended up with an error message. Very confused, I am not a technical person. How to get rid of this error? How to check whether this is compatible with the system? Please help me. Thanks a lot.
Windows Movie Maker
E:\handycam\o2-09-2007\20070821163510.mpg could not be imported. An interface has too many methods to fire events from
- 145 reads
- 1 comment
Hi all,
I am getting this Access violation error message when I work around the VSO Blu-ray converter ultimate. In the google search I am not able to find the solution. But I have installed NVidia graphics card with CUDA support in the system and also I updated the windows. Even after these changes I get the same error message. Please help me to resolve this error and to findsolutions. Thanks a lot.
Access violation at address 00966154 in module 'BlurayConverterUltimate.exe'. Read of address 00000004.
- 197 reads
- 1 comment
Hi experts,
When I try to play a video file I ended up with an error message Overdrive Media Console error. The situation is when I try to upgrade the security of windows media player to the latest version; I am not able to continue with the process something is blocking me. I am not aware of the issue. Does anyone know how to fix this problem? Pleasehelp. Thanks.
OverDrive Media Console
Unable to acquire a license to play the selected title.
- 293 reads
- 2 comments
I am getting this weird error message when I try to play a video file. I am little bit scared whether this error might infect my system. The error message gives me three options but only one is enabled. Can I continue with this option? Do I need to upgrade mu antivirus? Someone could help me to solve this error. Thanks for your help.
Video ActivateX Object Error:
Your browser cannot display this video file. You need to download new version of Video ActivateX Object to play this video file.
- 214 reads
- 1 comment
Hello experts,
I am getting this error message for most the .avi files in the computer. I tried to update the Windows Media player but nothing helped me. Even the web help is not supporting me to play the video file. I tried the general methods like restarting the computer but even that is not working. Contribute your ideas please. Your help is appreciated. Thank you.
Message from webpage
Windows Media Player encountered a problem while playing the file.
- 99 reads
- 1 comment
Hi all,
I am in the problem, trying to solve the File error. This error resulted when I try to install the Pinnacle PCTV version 5.4.1. I tired these methods to solve the error but nothing worked. I tried to update the drivers through Device Manager but it states that no new version is found. I am in the critical situation, Please help. Thanks.
The following error occurred on the file 'C:\Program Files\Pinnacle\TVCenter Pro\Skins\chameleon'.
Access is denied.
- 198 reads
- 1 comment


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Are you Elena Biagini?Claim your profile
Publications (126)681.92 Total impact
Article: Predictors of nonsimultaneous interventricular delay at cardiac resynchronization therapy optimization[Show abstract] [Hide abstract]
ABSTRACT: Cardiac resynchronization is a well tolerated and effective therapy for heart failure, but 30% of patients still do not respond to biventricular pacing. Optimization of device settings, in particular interventricular delay value, represents a plausible target for improving these results, but available literature is discordant. We aimed our study at the identification of the best suitable candidates to interventricular delay optimization. A total of 77 consecutive patients with optimized drugs therapy underwent clinical, echocardiographic and electrocardiographic evaluation before and after 6 months from implantation of a biventricular defibrillator in accordance to current guidelines. In each patient, atrioventricular and interventricular delay values were optimized at predischarge with echocardiogram. The only predictor of an optimized interventricular delay value different from simultaneous (i.e. standard shipment setting), at both univariate and multivariate analyses, was a QRS duration greater than 160 ms (odds ratio 22.958; P = 0.003) with a sensitivity of 70.9%. Candidates to cardiac resynchronization therapy with a basal QRS greater than 160 ms have a higher chance of requiring echo-guided tailoring of interventricular delay value. A strategy based on these data can potentially improve device programming, reducing by one-third the need for optimization, according to our findings, and at the same time avoid unnecessary time-consuming procedures.Journal of Cardiovascular Medicine 12/2014; DOI:10.2459/JCM.0000000000000196 · 1.41 Impact Factor
Article: Prognostic Value of Quantitative Contrast-Enhanced Cardiovascular Magnetic Resonance for the Evaluation of Sudden Death Risk in Patients With Hypertrophic Cardiomyopathy[Show abstract] [Hide abstract]
ABSTRACT: Background-Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden death in the young, although not all patients eligible for sudden death prevention with an implantable cardioverter-defibrillator are identified. Contrast-enhanced cardiovascular magnetic resonance with late gadolinium enhancement (LGE) has emerged as an in vivo marker of myocardial fibrosis, although its role in stratifying sudden death risk in subgroups of HCM patients remains incompletely understood. Methods and Results-We assessed the relation between LGE and cardiovascular outcomes in 1293 HCM patients referred for cardiovascular magnetic resonance and followed up for a median of 3.3 years. Sudden cardiac death (SCD) events (including appropriate defibrillator interventions) occurred in 37 patients (3%). A continuous relationship was evident between LGE by percent left ventricular mass and SCD event risk in HCM patients (P=0.001). Extent of LGE was associated with an increased risk of SCD events (adjusted hazard ratio, 1.46/10% increase in LGE; P=0.002), even after adjustment for other relevant disease variables. LGE of >= 15% of LV mass demonstrated a 2-fold increase in SCD event risk in those patients otherwise considered to be at lower risk, with an estimated likelihood for SCD events of 6% at 5 years. Performance of the SCD event risk model was enhanced by LGE (net reclassification index, 12.9%; 95% confidence interval, 0.3-38.3). Absence of LGE was associated with lower risk for SCD events (adjusted hazard ratio, 0.39; P=0.02). Extent of LGE also predicted the development of end-stage HCM with systolic dysfunction (adjusted hazard ratio, 1.80/10% increase in LGE; P<0.03). Conclusions-Extensive LGE measured by quantitative contrast enhanced CMR provides additional information for assessing SCD event risk among HCM patients, particularly patients otherwise judged to be at low risk.Circulation 08/2014; 130(6):484-95. DOI:10.1161/CIRCULATIONAHA.113.007094 · 14.95 Impact Factor
Article: Significance of Sarcomere Gene Mutations Analysis in the End-Stage Phase of Hypertrophic Cardiomyopathy[Show abstract] [Hide abstract]
ABSTRACT: End-stage hypertrophic cardiomyopathy (ES-HC) has an ominous prognosis. Whether genotype can influence ES-HC occurrence is unresolved. We assessed the spectrum and clinical correlates of HC-associated mutations in a large multicenter cohort with end-stage ES-HC. Sequencing analysis of 8 sarcomere genes (MYH7, MYBPC3, TNNI3, TNNT2, TPM1, MYL2, MYL3, and ACTC1) and 2 metabolic genes (PRKAG2 and LAMP2) was performed in 156 ES-HC patients with left ventricular (LV) ejection fraction (EF) <50%. A comparison among mutated and negative ES-HC patients and a reference cohort of 181 HC patients with preserved LVEF was performed. Overall, 131 mutations (36 novel) were identified in 104 ES-HC patients (67%) predominantly affecting MYH7 and MYBPC3 (80%). Complex genotypes with double or triple mutations were present in 13% compared with 5% of the reference cohort (p = 0.013). The distribution of mutations was otherwise indistinguishable in the 2 groups. Among ES-HC patients, those presenting at first evaluation before the age of 20 had a 30% prevalence of complex genotypes compared with 19% and 21% in the subgroups aged 20 to 59 and ≥60 years (p = 0.003). MYBPC3 mutation carriers with ES-HC were older than patients with MYH7, other single mutations, or multiple mutations (median 41 vs 16, 26, and 28 years, p ≤0.001). Outcome of ES-HC patients was severe irrespective of genotype. In conclusion, the ES phase of HC is associated with a variable genetic substrate, not distinguishable from that of patients with HC and preserved EF, except for a higher frequency of complex genotypes with double or triple mutations of sarcomere genes.The American Journal of Cardiology 06/2014; 114(5). DOI:10.1016/j.amjcard.2014.05.065 · 3.43 Impact Factor
Article: [Paradigm shifts in aortic pathology: clinical and therapeutic implications. Clinical imaging in chronic and acute aortic syndromes. The aorta as a cause of cardiac disease].[Show abstract] [Hide abstract]
ABSTRACT: Multimodal imaging plays a pivotal role in the assessment of the thoracic aorta, both in chronic and acute settings. Moving from improved knowledge on the structure and function of the aortic wall, as well as on its pathophysiology and histopathology, appropriate utilization of each imaging modality results into a better definition of the patient's need and proper treatment strategy. This review is aimed at highlighting the most critical aspects in this field, providing cardiologists with some novel clues for the imaging approach to patients with thoracic aortic disease.Giornale italiano di cardiologia (2006) 06/2014; 15(6):363-75. DOI:10.1714/1582.17280
[Show abstract] [Hide abstract]
ABSTRACT: Most usually, the aortic tunnels empty into the left ventricle. Very rarely, they open to the left atrium. The essence of the aortic tunnels is that they bypass the hinges of the valvar leaflets within the aortic root. We have recently encountered an aorto-left atrial tunnel satisfying this criterion.Cardiovascular pathology: the official journal of the Society for Cardiovascular Pathology 02/2014; 23(4). DOI:10.1016/j.carpath.2014.02.002 · 1.63 Impact Factor
Article: Risk of Sudden Death and Outcome in Patients With Hypertrophic Cardiomyopathy With Benign Presentation and Without Risk Factors[Show abstract] [Hide abstract]
ABSTRACT: Patients with hypertrophic cardiomyopathy (HC) are reported to have a mortality rate of about 1.0% per year, and those patients without sudden death risk factors and with no or mild symptoms are generally considered to have a benign clinical presentation. However, the risk of sudden death and the outcome in this latter subgroup have not been investigated systematically and remain unresolved. We assessed the risk of sudden death and outcome in 653 consecutive patients with HC without risk factors and with no or mild symptoms. Over a median follow-up of 5.3 years, 35 patients (5.4%) died of HC-related causes. Mean age at death was 46 ± 20 years in patients who died suddenly and 66 ± 15 and 72 ± 9 years, respectively, in patients who died of heart failure or stroke. Event rate was 0.6% per year for sudden death, 0.2% per year for heart failure death, and 0.1% per year for stroke-related death. Sudden death risk was independently and inversely related to age, and risk of heart failure or stroke death was directly related to age (p = 0.020). At 10 years after the initial evaluation, sudden death risk was 5.9%, with sudden death rate being the lowest (0.3% per year) in patients with normal left atrial dimension (≤40 mm). In conclusion, in patients with HC without conventional risk factors and with no or mild symptoms, the risk of sudden death was not negligible, with an event rate of 0.6% per year. Heart failure and stroke-related death were less common and largely confined to older patients. These results underscore the need for a more accurate assessment of the sudden death risk in patients with HC.The American journal of cardiology 02/2014; 113(9). DOI:10.1016/j.amjcard.2014.01.435 · 3.58 Impact Factor
Article: A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (HCM Risk-SCD).[Show abstract] [Hide abstract]
ABSTRACT: Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden cardiac death (SCD) in young adults. Current risk algorithms provide only a crude estimate of risk and fail to account for the different effect size of individual risk factors. The aim of this study was to develop and validate a new SCD risk prediction model that provides individualized risk estimates. The prognostic model was derived from a retrospective, multi-centre longitudinal cohort study. The model was developed from the entire data set using the Cox proportional hazards model and internally validated using bootstrapping. The cohort consisted of 3675 consecutive patients from six centres. During a follow-up period of 24 313 patient-years (median 5.7 years), 198 patients (5%) died suddenly or had an appropriate implantable cardioverter defibrillator (ICD) shock. Of eight pre-specified predictors, age, maximal left ventricular wall thickness, left atrial diameter, left ventricular outflow tract gradient, family history of SCD, non-sustained ventricular tachycardia, and unexplained syncope were associated with SCD/appropriate ICD shock at the 15% significance level. These predictors were included in the final model to estimate individual probabilities of SCD at 5 years. The calibration slope was 0.91 (95% CI: 0.74, 1.08), C-index was 0.70 (95% CI: 0.68, 0.72), and D-statistic was 1.07 (95% CI: 0.81, 1.32). For every 16 ICDs implanted in patients with ≥4% 5-year SCD risk, potentially 1 patient will be saved from SCD at 5 years. A second model with the data set split into independent development and validation cohorts had very similar estimates of coefficients and performance when externally validated. This is the first validated SCD risk prediction model for patients with HCM and provides accurate individualized estimates for the probability of SCD using readily collected clinical parameters.European Heart Journal 10/2013; DOI:10.1093/eurheartj/eht439 · 14.72 Impact Factor
Article: [Paradigm shifts in aortic pathology: clinical and therapeutic implications. Biology and pathology of the aortic wall].[Show abstract] [Hide abstract]
ABSTRACT: Improved knowledge of the structure and function of the aortic wall, as well as its pathophysiology and histopathology, will result in an increasing impact on clinical evaluation and treatment of thoracic aortic diseases. This opinion paper highlights the main "paradigmatic shifts" in this field, providing cardiologists with some novel clues for the clinical approach to patients with thoracic aortic disease.Giornale italiano di cardiologia (2006) 02/2013; 14(2):97-109. DOI:10.1714/1218.13522
Article: Effects of myocardial fibrosis assessed by MRI on dynamic left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy: a retrospective database analysis[Show abstract] [Hide abstract]
ABSTRACT: While implications of myocardial fibrosis on left ventricular (LV) function at rest have been studied in hypertrophic cardiomyopathy (HCM), the pathophysiological consequences on dynamic LV outflow tract (LVOT) gradient have so far not been investigated in detail. To evaluate the influence of myocardial fibrosis, detected by MRI as late-gadolinium enhancement (LGE), on LVOT gradient in HCM. Retrospective database analysis. A single Italian cardiomyopathies referral centre. Seventy-six HCM patients with normal ejection fraction at rest. Patients underwent cardiac MR and performed bicycle exercise echocardiogram within a month. LGE was present in 54 patients (71%), ranging from 0.2% to 32.4% of LV mass. There was a weak correlation between the amount of fibrosis and LVOT gradient variation during exercise in the overall population (r=-0.243, p=0.034) and a stronger correlation in patients with obstructive HCM at rest (r=-0.524, p=0.021). Patients with an LVOT gradient increase ≥50 mm Hg during exercise had a significantly lesser extent of fibrosis than those with an increase <50 mm Hg (0.7% (IQR 0-2.4) vs 3.2% (IQR 0.2-7.4), p=0.006). The extent of fibrosis was significantly lower among the highest quartiles of LVOT gradient increase (p=0.009). In patients with HCM and normal ejection fraction at rest, myocardial fibrosis was associated with a lower increase in LVOT gradient during exercise, probably due to a lesser degree of myocardial contractility recruitment. This negative association was more evident in patients with an obstructive form at rest.BMJ Open 09/2012; 2(5). DOI:10.1136/bmjopen-2012-001267 · 2.06 Impact Factor
JACC. Cardiovascular imaging 07/2012; 5(7):755-8. DOI:10.1016/j.jcmg.2012.02.015 · 14.29 Impact Factor
Article: Disease profile and differential diagnosis of hereditary transthyretin-related amyloidosis with exclusively cardiac phenotype: an Italian perspective[Show abstract] [Hide abstract]
ABSTRACT: AimsHereditary transthyretin (TTR)-related amyloidosis (ATTR) is mainly considered a neurologic disease. We assessed the phenotypic and genotypic spectra of ATTR in a Caucasian area and evaluated the prevalence, genetic background, and disease profile of cases with an exclusively cardiac phenotype, highlighting possible hints for the differential diagnosis with hypertrophic cardiomyopathy (HCM) and senile systemic amyloidosis (SSA).Methods and resultsIn this Italian multicentre study, 186 patients with ATTR were characterized at presentation. Thirty patients with SSA and 30 age-gender-matched HCM patients were used for comparison. Phenotype was classified as exclusively cardiac (n = 31, 17%), exclusively neurologic (n = 46, 25%), and mixed cardiac/neurologic (n = 109, 58%). Among the eight different mutations responsible for an exclusively cardiac phenotype, Ile68Leu was the most frequent. Five patients with an exclusively cardiac phenotype developed mild abnormalities at neurological examination, but no symptoms during a 36-month follow-up (range: 14-50). Exclusively cardiac phenotype was characterized by male gender, age >65 years, heart failure symptoms, symmetric left ventricular (LV) 'hypertrophy', and moderately depressed LV ejection fraction. This profile was similar to SSA, but relatively distinct from HCM. Compared with patients with a mixed phenotype, patients with an exclusively cardiac phenotype showed a more pronounced cardiac involvement on both echocardiogram and electrocardiogram (ECG).ConclusionA clinically relevant subset of Caucasian ATTR patients present with an exclusively cardiac phenotype, mimicking HCM or SSA. Echocardiographic and ECG findings are useful to differentiate ATTR from HCM but not from SSA. The role of liver transplantation in these patients should be reconsidered.European Heart Journal 06/2012; 34(7). DOI:10.1093/eurheartj/ehs123 · 14.72 Impact Factor
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ABSTRACT: The need for a collaborative approach to complex inherited diseases collectively referred to as laminopathies, encouraged Italian researchers, geneticists, physicians and patients to join in the Italian Network for Laminopathies, in 2009. Here, we highlight the advantages and added value of such a multidisciplinary effort to understand pathogenesis, clinical aspects and try to find a cure for Emery-Dreifuss muscular dystrophy, Mandibuloacral dysplasia, Hutchinson-Gilford Progeria and forms of lamin-linked cardiomyopathy, neuropathy and lipodystrophy.Orphanet Journal of Rare Diseases 06/2012; 7:37. DOI:10.1186/1750-1172-7-37 · 3.96 Impact Factor
Article: [Gender effect on cardiomyopathy].[Show abstract] [Hide abstract]
ABSTRACT: The role of a gender effect (that means differences in clinical manifestations, access to therapies and response to treatments according to gender) in cardiomyopathies remains a matter of debate. Although recent studies have evaluated the differences in the clinical features and prognosis between the two sexes, many issues remain to be elucidated. At present, the only sex-specific condition that affects females is peripartum cardiomyopathy. Recent evidence suggests a pathogenetic role of a prolactin derivative, and ongoing clinical trials are investigating the possibility of targeted therapies using prolactin secretion inhibitors, such as bromocriptine and carbegoline. Although women were considered so far only carriers of X-linked diseases (Anderson-Fabry disease, Danon disease, Hunter syndrome and dystrophinopathies), clinical experience showed a wide spectrum of clinical manifestations in females due to random X chromosome inactivation. Conversely, in mitochondrial diseases (with matrilineal inheritance), cardiomyopathies may occur in the context of clinical multisystemic involvement without significant gender-related differences. Autosomal inherited cardiomyopathies also show different phenotypes and prognostic impact according to gender. The hypothesis of a premenopausal protective role of female hormones towards myocardial involvement has been raised by recent data on transtiretin-related amyloidosis and hypertrophic cardiomyopathy. Preexisting cardiomyopathies may affect pregnancy, labor and delivery in women, since all these conditions are associated with important hemodynamic changes. Women with low-risk hypertrophic cardiomyopathy (asymptomatic and without left ventricular outflow tract gradient) usually can tolerate pregnancy. Conversely, women who are symptomatic before pregnancy or have severe hypertrophy with important outflow tract gradient are at higher risk and should be referred to a tertiary center to be evaluated on a case by case basis. Pregnancy in women with dilated cardiomyopathy and significant left ventricular systolic dysfunction represents a high-risk condition. In addition, information on the clinical course and potential complications in pregnant women with arrhythmogenic right ventricular cardiomyopathy or restrictive cardiomyopathy is limited to individual reports.Giornale italiano di cardiologia (2006) 06/2012; 13(6):424-31. DOI:10.1714/1073.11761
Article: Reply to Della Corte et al.European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery 01/2012; DOI:10.1093/ejcts/ezs008 · 2.40 Impact Factor
Article: An unusual case of familial hypertrophic cardiomyopathy with left ventricular systolic dysfunction: a still unsolved diagnosis[Show abstract] [Hide abstract]
ABSTRACT: A 35-year-old woman was referred to our centre for clinical management of hyper-trophic cardiomyopathy (HCM) with left ven-tricular (LV) systolic dysfunction (end-stage evolution). She was recently diagnosed else-where because of palpitations. Her 7-year-old daughter underwent familiar screening and she was diagnosed with classic HCM. She was completely asymptomatic without extracardiac or systemic manifestations. During the follow-ing years, they both experienced a similar clin-ical course with worsening dyspnoea and pro-gressive deterioration of LV systolic function. They both underwent heart transplantation, the mother at the age of 47 and the daughter at the age of 23, respectively. Many diagnostic hypotheses, including sarcomeric HCM, Anderson-Fabry disease, glycogen storage dis-eases and mitochondrial cardiomyopathies have been taken into account. The diagnostic work-up included serial electrocardiogram and echocardiographic assessments, pathologic evaluation of the explanted hearts and genetic analysis of 8 sarcomeric and 3 metabolic genes. Even if a shared HCM phenotype (LV systolic dysfunction in two first-degree female family members associated with a likely auto-somal dominant inheritance and absence of extracardiac or multisystemic manifestations) could support a temptative diagnosis of sar-comeric HCM, a definitive diagnosis could not be reached, due to the lack of genetic analysis to confirm such diagnosis.01/2012; 2(1). DOI:10.4081/cardiogenetics.2012.e8
Article: Restrictive cardiomyopathy and hypertrophic cardiomyopathy overlap: the importance of the phenotype01/2012; 2(1):10. DOI:10.4081/cardiogenetics.2012.e10
Article: Prognostic significance of baseline ST-T-wave abnormalities in diagnostic stress echocardiography[Show abstract] [Hide abstract]
ABSTRACT: The aim of this study was to determine whether resting ST-T wave abnormalities (ST-Ta) provide incremental prognostic information in patients with no history of coronary artery disease undergoing dobutamine stress echocardiography (DSE). We evaluated 1308 consecutive patients without previous myocardial infarction (MI) or revascularization who underwent DSE. Ischemia was defined as new or worsening wall motion abnormalities. End points during follow-up were all-cause death and cardiac death/nonfatal MI. ST-Ta were detected in 162 (12%) patients. The incidence of ischemia was higher in patients with baseline ST-Ta than patients without [74 (46%) vs. 327 (28%), P=0.00001]. During a follow-up of 4.6 ± 3 years, cardiac death/nonfatal MI occurred in 42 (26%) patients with resting ST-Ta and in 157 (14%) patients without resting ST-Ta (P<0.001). Patients with ST-Ta had a higher annual cardiac death/nonfatal MI rate compared with patients without, both in the presence of normal DSE (3.2 vs. 1.4%, P=0.01) as well as abnormal DSE (5.3 vs. 3%, P<0.001). In a Cox proportional modeling, resting ST-Ta added incremental value over clinical and stress echocardiographic data for the prediction of death (global χ 125, 140, 150, respectively; P<0.05) and cardiac death/nonfatal MI (global χ 79, 100, 111, respectively; P<0.05). Baseline ST-Ta are associated with an increased risk of cardiac death/nonfatal MI and all-cause mortality, incremental to clinical data and DSE results. The associated risk is persistent among patients with normal DSE.Coronary artery disease 09/2011; 22(8):559-64. DOI:10.1097/MCA.0b013e32834c74da · 1.56 Impact Factor
Article: The elusive link between aortic wall histology and echocardiographic anatomy in bicuspid aortic valve: implications for prophylactic surgery[Show abstract] [Hide abstract]
ABSTRACT: Prediction of aortic dissection or rupture is extremely difficult in patients with bicuspid aortic valve. We aimed to identify clinical and echocardiography predictors of histological abnormalities of the aortic wall in patients with bicuspid aortic valve undergoing aortic surgery. We assessed the histology of the aortic wall and clinical and echocardiography variables in a cohort of patients with bicuspid aortic valve (n = 127) and a wide spectrum of valvar disease who underwent replacement of the ascending aorta (with or without aortic valve surgery). Histology was classified using a 5-grade system developed by Larson and Edward. Histological alterations of the aortic wall were absent/mild (grade 0-1) in 77 patients (61%) and moderate/severe (grade 2-3) in 50 (39%). Patients with moderate/severe histological alterations were younger (47 ± 17 vs 53 ± 16; p = 0.042). Eighteen patients out of 48 (38%) with an ascending aorta diameter ≤ 4.5 cm had grade 2-3 aortic wall disease as did 8 out of 18 (44%) with a diameter ≤ 4 cm. Nineteen out of 46 (41%) patients with a maximal ascending aortic area/height ratio < 10 cm(2) m(-1) had moderate/severe histological alterations. Multivariate logistic regression analysis showed that the indexed diameter of the aortic annulus was significantly associated with grade 2-3 aortic wall disease (odds ratio (OR): 12.22, 95% confidence interval (CI): 1.65-90.38, p = 0.014). A high proportion of patients with bicuspid aortic valve and mild to moderate aortic dilatation have severe histological abnormalities of the aortic wall that are not predictable by clinical and echocardiographic findings. These observations suggest that risk stratification for aortic dissection or rupture in patients with bicuspid aortic valve is so far quite suboptimal and future investigations are warranted.European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery 08/2011; 41(2):322-7. DOI:10.1016/j.ejcts.2011.05.064 · 2.40 Impact Factor
Article: Effects of cardiac resynchronisation therapy on dilated cardiomyopathy with isolated ventricular non-compaction[Show abstract] [Hide abstract]
ABSTRACT: To compare the effects of cardiac resynchronisation therapy (CRT) on left ventricular (LV) reverse remodelling in patients with dilated cardiomyopathy (DCM) associated or not with isolated ventricular non-compaction (IVNC). 52 patients with heart failure, candidates for CRT, were recruited: 20 patients with IVNC associated with DCM (IVNC-DCM) without other coexisting cardiac diseases and 32 patients with DCM without IVNC matched for age, gender, body surface area and LV systolic function. Standard and contrast echocardiography were used to assess LV volumes and function and to optimise visualisation of the endocardial border at baseline and at 6 months' follow-up. Patients with heart failure were subsequently classified as CRT negative responders, non-responders, responders or super-responders based on different LV reverse remodelling 6 months after CRT implantation. Different types of CRT response were observed in IVNC-DCM and DCM patients. In particular, in IVNC-DCM patients the percentage of super-responders was significantly higher than for patients with DCM (60% vs 28%, respectively, p = 0.023). In addition, the number of IVNC segments had a trend towards reduction with respect to baseline (4 (3-6)) at 6 months' follow-up (3 (1-5); p = 0.067). Finally, in IVNC-DCM, the patients with a higher number of IVNC segments at baseline (>4) were more likely to be responders or super-responders than patients with ≤ 4 IVNC segments (p = 0.003). Patients with IVNC-DCM had greater LV reverse remodelling after CRT than patients with DCM. The greater the area of non-compaction (higher number of IVNC segments) the greater the chance of achieving CRT response and greater LV reverse remodelling.Heart (British Cardiac Society) 02/2011; 97(4):295-300. DOI:10.1136/hrt.2010.211607 · 6.02 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: A nonhereditary form of systemic amyloidosis associated with wild-type transthyretin causes heart involvement predominantly in elderly men (systemic senile amyloidosis, or SSA). However, hereditary transthyretin-related amyloidosis (ATTR) is the most frequent form of familial systemic amyloidosis, a group of severe diseases with variable neurological and organ involvement. ATTR remains a challenging and widely underdiagnosed condition, owing to its extreme phenotypic variability: the clinical spectrum of the disease ranges from an almost exclusive neurologic involvement to a strictly cardiac presentation. Such heterogeneity principally results from differential effects of the various reported transthyretin mutations, the geographic region the patient is from and, in the case of the most common mutation, Val30Met, whether or not large foci of cases occur (endemic versus nonendemic aggregation). Genetic or environmental factors (such as age, sex, and amyloid fibril composition) also contribute to the heterogeneity of ATTR, albeit to a lesser extent. The existence of exclusively or predominantly cardiac phenotypes should lead clinicians to consider the possibility of ATTR in all patients who present with an unexplained increase in left ventricular wall thickness at echocardiography. Assessment of such patients should include an active search for possible red flags that can point to the correct final diagnosis.Nature Reviews Cardiology 07/2010; 7(7):398-408. DOI:10.1038/nrcardio.2010.67 · 10.40 Impact Factor
Top Journals
Università degli Studi di SienaSiena, Tuscany, Italy
Policlinico S.Orsola-MalpighiBolonia, Emilia-Romagna, Italy
University of Bologna
Bolonia, Emilia-Romagna, Italy
- • Department of Experimental, Diagnostic and Specialty Medicine DIMES
- • Institute of Cardiology
Albert Schweitzer ZiekenhuisDordt, South Holland, Netherlands
Erasmus Universiteit Rotterdam
Rotterdam, South Holland, Netherlands
- Department of Cardiology
Università degli Studi del SannioBenevento, Campania, Italy
Erasmus MC
Rotterdam, South Holland, Netherlands
- Department of Cardiology
The Catholic University of AmericaWashington, Washington, D.C., United States
Leiden University Medical Centre
Leiden, South Holland, Netherlands
- Department of Cardiology
Catholic University of the Sacred HeartMilano, Lombardy, Italy
Leiden UniversityLeyden, South Holland, Netherlands
Sacred Heart UniversityФеърфилд, Connecticut, United States


text:
Look wut I got! :)
I think they are so cool! Just showed up in the morning, by noon they were open so I took a picture, and by next morning they were gone :(
In my old terrarium, I used to get them, but they were yellow, these ones are pure white.
Ana :)
Here is a link that might be useful: mushrooms
Well, thank you, Theresa!
Here's a better view of the whole terrarium. Is hard to take a pic of it because is standing behind the sink, on a window alcove, so when I take a pic, the reflection of the faucets, or me, etc. shows, so I have to find an angle and cover the sink with a dark cloth... LOL!
The gray rock in the back, far right, is a waterfall, is small (12"tall x 10" across x 10"deep) but makes a nice water noise and it looks good. The terrarium is 16"tall x 36" across x 14" deep.
Ana :)
Here is a link that might be useful: terrarium update
Ana, I'm soooooooooo jealous! All of my colourful plants died, so I'm left with just green (and a bit of red). Your tank has grown and settled in so beautifully! And after seeing that ficus quercifolia again, I'm turning green myself. . . =) I have also been dying to get some mushrooms in my tank. Don't you just love them? They really make it look so natural. I find it happens more with soil substrates than with bark chips. Wonder why? Plenty of mushrooms grow on trees in the wild. Oh well, great job on the tank! You should post a pic on the discussions side for those who rarely check the gallery (like me). =)
ladybug_guam, I think your set up is totally disgusting! (Thats my way of saying that its one of the most beautiful set ups Ive seen and I will try to make one that looks similiar to it as Im jealous that its not mine!) So...yeah! That'll teach you! =)


text:
Protect & Feed Thailand's Elephants
Roll over image to zoom in
Protect Asian elephants from a life of begging on city streets: help provide food & care in elephant sanctuaries.
Elephants have been revered in Thai culture for thousands of years. These intelligent giants once helped their mahouts (those who work with and care for them) with farming, construction, and more, but as new technologies emerged, most found themselves restricted to logging. Then, in 1990, Thailand outlawed logging to preserve what little forest it had left.
Suddenly, thousands of domesticated elephants and their mahouts had no means to earn a living. Many were forced to the streets to began unhealthy existence which does not provide enough food for the elephants, who need to eat 400-500 pounds of quality vegetation every single day.
Turning elephants loose in the wild is not an option, as there is not enough habitat left for even basic survival. Stepping in to help, the Elephant Nature Foundation is working hard to create and maintain elephant sanctuaries where these gentle behemoths will be able to roam freely, and where their mahouts are paid a living wage to maintain the sanctuary — a winning scenario all around.
You can help this wonderful project! Donations to this Gift That Gives More™ provides food and care for elephants in Thailand. Provide one day ($35) or half a day ($17.50) of enough grass, bamboo, fruit, & daily care for one elephant.
Report from the Field
From Eleonor Content, Executive Director of Abraham Foundation for The Surin Project:
I wanted to write a short update about things at the elephant rescue project in Surin, Thailand. As I wrote in my last email, the enclosure was single handedly funded by the donations from The Animal Rescue Site. It has made the hugest difference in the lives of these poor gentle giants. The enclosure gives them the opportunity to eat, bathe and graze at will. They are bonding with each other in the most moving way.
We cannot thank you enough for having our project on The Animal Rescue Site. The money we have received has made the most dramatic difference in the lives of these elephants.
The Elephant Nature Foundation works tirelessly to preserve and protect Asian elephants. It is their mission to save the Asian elephant from extinction and give domesticated elephants a life worth living by preserving habitat and increasing public awareness on humane treatment practices.
Free Standard Shipping in the U.S. on your entire cart when you donate $15.00 or more in our Gift That Gives More™ program. See Current Promotions for details.
Why a Gift That Gives More™ is a smart, effective donation.
100% of your donation will go to the program described above as a grant through GreaterGood.org. GreaterGood stores do not receive any profit from donations through this Gift That Gives More™; we bring it to you in the spirit of the greater good. We even pay the credit card transaction fee, so every cent of your donation goes to charity.
Please note: A free downloadable certificate is available to print for easy gift giving for any non-disaster related Gift That Gives More™. The "gift message" field during check-out does not apply to your Gift That Gives More™ certificate.
Your donation is 100% tax-deductible in the U.S.A.
You will receive a receipt from GreaterGood.org for your taxes. GreaterGood.org has ultimate authority and discretion with regard to the distribution of its funds. All expenditures made are consistent with the exempt purposes of GreaterGood.org.
Check with your employer: your company may match your donation.
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You guys know by now that I'm a big fan of making my own sauces. And, this Teriyaki Sauce is one that we've been making for years. I think we started making this recipe because we couldn't find a bottled Teriyaki Sauce that we really liked. Basically, anywhere you want to use a bottle of Teriyaki Sauce or marinade, use this, and feel better knowing that you know everything in it, and that it tastes way better than any bottled stuff.
Easy Homemade Pizza Sauce
Italian Apricot Stew
I'm bringing you the next Childhood Favorites Remade! This dish is something my mom made when I was in high school. Italian Apricot Chicken, which I'm now calling Italian Apricot Stew. It was super easy to make. I think this Italian Apricot Stew recipe stands the test of time. Still really easy, and super yummy, full flavored with lots of herbs and spices. Vegetarian or non-vegetarian.
Homemade Onion Soup Mix
Dried Apricot Jam
You may remember, I started doing childhood favorites remade a couple of years ago. I wanted the new versions to reflect out current eating styles: healthier, less fat, no trans-fats, fewer processed items, more veggies, maybe even just tastier. So this Dried Apricot Jam is one of the ingredients in the final dish. But, this jam is also wonderful on morning toast! Come take a look at this easy to make year-round jam.


text:
Grand Hotel Murgavets
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TripAdvisor Reviews Grand Hotel Murgavets Pamporovo
Travel Blogs from Pamporovo
... around. After lunch, brolly at the ready we walked to the old town. The majority of the buildings are in good repair, the mansions are all very grand, built in a symmetrical design. The smaller houses have balconies and first floors that hang over the streets, that wind up the hillside, every so often there is a church, some small others much larger all built at different times but they all have the same design. A few if the houses still retain ...
A very wet Plovdiv
It wasn't raining when we set off and the sky was pretty dark but we convinced ourselves it would stay dry...... We did get the walk into town in the dry and our first stop was a Roman villa, now part of a major road underpass. The site was a Bishop's Palace and many of the mosaic floors were still in tact. They also found a lot of beautiful Roman glass; amazing it's even still recognisable never ...
Thracian tombs and Roman Plovdiv (5125 km)
... stall of drinks, post cards and would be busy knitting colourful slippers to sell to you. What a contrast.
After the tombs Charlie navigated me to a giant lake up a long straight road, riddled with pot holes. It was slow muddy progress but the lake lunch spot was worth the trouble.
We arrived in Plovdiv about 4.00 and as the weather is supposed to be wet tomorrow we set off to explore. Much of ...
Think we are getting good at this boarding malarky
... really boarded I these conditions before and it was quite an experience. The afternoons became way too slushy though so our best work was in the morning.
Can not recommend Pamporovo and the apartments and lessons we had enough.
Snow-white ...
Bulgaria ski trip
... hours of laying on airport floors, we were boarded, only to be told the door wouldn't close and engineer was required to fix problem before take off! Another half hour later and eventually we were on our way to Sofia! As we were so late arriving we had missed the last bus to Pamporovo ski resort which is 4 hrs from Sofia so we had no choice but to find a hostel for the night, get our head down and catch first bus the next morning! Up early we rose and ...


text:
Friday, November 23, 2012
Maybe They Knew
Wild turkeys were spotted this Thanksgiving Day on Westport's Heron Lake Lane. (CLICK TO ENLARGE) Charlie Colasurdo for WestportNow.com
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Steve Mays (1950-2014) was Senior Pastor of Calvary Chapel South Bay in Gardena, California, for over thirty three years
before the Lord called him home in October 2014. He was noted for his bold, strong, and practical teaching styleand unique voice. Calvary
Chapel South Bay, the church where Pastor Steve fulfilled the leadership role for over three decades, grew from a small 75-person fellowship
to a church with a weekly attendance surpassing eight thousand. With a true shepherds heart, Pastor Steve reached out to everyone the Lord
brought his way, including corporate leaders, political leaders, media, fellow pastors and ministry leaders, as well as global leaders and
institutions who often asked him to share Gods truth in various platforms and to a wide array of people. The Lord gave him many
opportunities to share the message of the Gospelfrom praying at the White House and speaking at the National Day of Prayer; giving Bible
studies at the Pentagon Prayer Breakfast and Christian Embassys United Nations outreach; and participating at the Oxford Round Table. Yet
there was a time in Steves life where none of this would ever have seemed possible.
Molested by a teacher as a youth, Steves life took a destructive path through drugs, gangs, violence and rage. For this bleak hoodlum,
life was nothing but suffering and anger. He was a heartbeat from hell
until he met Jesus Christ.
Radically transformed in the midst of a revival sweeping through the nation later called the Jesus movement, Steve found himself a
changed manrenewed by saving faith in Jesus Christ. God had touched the untouchable.
Over the years, the Lord would continue to mold and change Steve from the inside out, preparing him for the ministry and equipping him as
a pastor. He faithfully served the flock at Calvary Chapel South Bay as the body grew from a small fellowship to the diverse, multi-ethnic
congregation that it is today. In his later years, he was frequently beset by physical infirmitiesmultiple back surgeries, and chronic
pain. Yet through it all, God gave him the strength to endure, using each ailment to draw him closer to Christand inspire others.
In the end, Steve Mays finished his race well.
I have fought the good fight, I have finished the race, I have kept the faith. Finally, there is laid up for me the crown of
righteousness, which the Lord, the righteous Judge, will give to me on that Day, and not to me only but also to all who have loved His
2 Timothy 4:7-8


text:
As a classical pianist, I've given concerts in cities all over the world. One of my tours took me to Japan full story
Seattle is home to some of America's most inspirational bands. One such group who proudly hails from the Emerald City full story
|Comments for:
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I'm glad the police are protecting us from these lunatic protesters. If I was the cheif I'd say they need more equipment.
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In its first lethal injection since a botched one last spring, Oklahoma executed a convicted killer with a three-drug method also used by Florida for an execution the same night.
Chainsaw-carved bears a good fit for local business man
Obituary published Jan. 16, 2015 in The Mexico Ledger
Hungarian Prime Minister Viktor Orban, often criticized for punishing banks, is being hailed as a hero for warding off financial disaster with his quest to rid the country of mortgages worth billions of Swiss francs.
Death Notice published Jan. 16, 2015 in The Mexico Ledger
Service times reported Jan. 16 in The Mexico Ledger
SpaceX sent a supply ship soaring flawlessly toward the International Space Station on Saturday, but the booster rocket ended up in pieces in the Atlantic following a failed attempt to land on a barge.
Critics say it's tougher the second time around, creating a successful sequel.Following last night's 70-66 win over Fulton, the second MHS win over the Hornets in less than week, the Bulldogs might agree with the above...
If a basketball game can be compared to a type of music, then last night's Community R-6 Lady Trojans game against the Elsberry Lady Indians was jazz, plain and simple. That's right. Jazz.The musical form filled...
Between tournaments and good old fashioned one-on-one team games, Ledgerland has kept busy with basketball this week. Here are the headlines and capsules on several of the games that took place.
- Events Calendar


text:
Do you like this article?
|Posted by:
|Varsha B.
|User Rating
|(26 Votes)
|fathima23, -Muskaan-, anishalakhani78, niki_09, Nikhi., cuteluv, coolfire, kyphfanz, Cutie_Pri, Sofia., Mysterygirl_me, nik_sweetpoison, k_anjali12, -Appsy-, precious_zeba, --Pravz--, shivani003, -Frozen-, MissArshi-, Roshni., pratsy
Iam sooooooooo happy that this movie is clicking with the Indian audience despite being a chick flick!!!!!! Rocking!!! :D
i watched it for sonamakapoor...
great article!!
glad to know its doing well!! i loved the movie =]
this article totallly contradicts ur prev article on ayesha.......
I love Jane Austen novels and liked Clueless so will give this movie a try!
i some times have a strong feeling that some, if not all these articles are paid ones. u praise some films sky high and they turn out to be unwatchable duds at the BO.
IF u guys lie! and don't know wht u guys are talking abt!
will watch for abhay
hey i heard this film on this forum being crappy? guess you gotta check out the film yourself to know if it crappy or not.
if i am not mistaken few days back here in IF i read an article about this movie being crappy ... what happened all of a sudden ... STRANGE
Ali Asgar who is seen as Dadi in Comedy Nights with Kapil, will ... 14
Sneha Wagh, speaks about her first Gudi Padwa post her wedding in this ... 1
Aditi Arya, the proud winner of this year's Femina Miss India World ...
Keeping a close eye on a celebrity's style quotient is something that ... 1


text:
Some physicists have done a study of the energy involved in turning water into wine. It seems that it may in fact have involved a very different process than what SMBC depicted in cartoon form a while back: [Read more...]
The Blog of Dr. James F. McGrath, Clarence L. Goodwin Chair in New Testament Language and Literature at Butler University, Indianapolis
Some physicists have done a study of the energy involved in turning water into wine. It seems that it may in fact have involved a very different process than what SMBC depicted in cartoon form a while back: [Read more...]
Young-earth creationism claims to take Genesis literally. It insists that the firmament mentioned there is not a solid dome, and that the "water above" the firmament were water vapors, a vapor canopy that provided the waters for the global flood. Unfortunately for this view, there is no evidence for it from the natural world. But [Read More...]
Young-earth creationism takes it upon itself to do something that none of the Biblical authors does. Even though there were lots of different views in Mesopotamia and Egypt, and later in Greece and Rome, about the processes involved in nature, we never see a Biblical author challenge any of those views. Not one. Sometimes, however, [Read More...]
Tyler Francke tackles Ray Comfort's silly stance on evolution, pointing out that one could say the same thing about the water cycle in light of what the Bible says. Click through to read his post. [Read more...]
Yesterday was a momentous occasion. For the first time since moving to Indianapolis more than a decade ago, my family lives in a home connected to city water. It isn't that we moved. Citizens Water recently put a main on our street, where previous utility companies had not done so. And then Bedell Plumbing connected [Read More...]
From Saturday Morning Breakfast Cereal [Read more...]
Someone on Facebook shared this quote attributed to Bruce Lee… Be like water …Empty your mind, be formless. Shapeless, like water. If you put water into a cup, it becomes the cup. You put water into a bottle and it becomes the bottle. You put it in a teapot, it becomes the teapot. Now, water [Read More...]
A friend shared this on Facebook. I am not sure whether it is real or a spoof (I have seen kitchier Christian marketing gimmicks). But I am confident that it isn't what Revelation 7 had in mind – or John 4, for that matter. [Read more...]
Jeff Carter made and shared the image below, which he gave the title "The Sandworms did not appreciate John the Baptizer." Squarely at the intersection of religion and science fiction – but of course, Dune already was… Thoughts? [Read more...]
In a conversation with a young-earth creationist here on this blog, I was struck by the irony of the fact that he offered, as one reason for rejecting evolution, the teaching of Scripture that we should not follow the ways or teachings of sinful human beings. How right he is, and how wrong at the [Read More...]
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text:
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Hôtel Ardiden - Luz-Saint-Sauveur
20, av. de l'Impératrice Eugénie - Luz-Saint-Sauveur1-877-662-6988
Perched on the mountain side in the spa district of Luz Saint Sauveur, the hotel Logis Ardiden welcomes guests to a charming, fully-equipped residence and a warm, family atmosphere.
The hotel has clean, comfortable rooms equipped with bath or shower and toilet, TV, and telephone. Free wired internet access is available in the hotel's public areas.
The hotel's restaurant serves a range of local specialities. Half-board service is available and prices may vary depending on the number of guests. After a hearty meal, take some time for yourself in the neighboring Luzea spa and fitness center.
Hotel Ardiden is a perfect starting point for guests wishing to discover the surrounding countryside or some of the major sites in the area. It is also close to a number of sports activities such as rafting, hiking, and skiing at the nearby slopes in the Luz Ardiden, Tourmalet and Gavarnie resorts.
Good family cuisineVenere Guest, Canada
These reviews have been left by customers who actually stayed at this hotel
Check Availability at Hôtel Ardiden
Breakfast at Hôtel Ardiden
A continental breakfast is served each morning for a fee.
Facilities at Hôtel Ardiden
- Bar
- Restaurant/Dining
- Meeting Room
- Lift/elevator
- Garden
- Pets accepted
- Newspapers
- Internet/Email services
- Ski room
Know before you go
Check-in: between 2 PM and 6 PM.
Check-out: before 10:30 AM.
PolicyExtra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- No onsite parking is available.
City tax and/or any other fees charged by the hotel
The following fees and deposits are charged by the property at time of service, check-in, or check-out.
- Fee for continental breakfast: EUR 7.50 per person (approximately)
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
National ratingThis hotel has received its official star rating from the French Tourism Development Agency, ATOUT France.
Hôtel Ardiden reviews
- July 2011
- Venere Guest
- Couple
- Canada
Good family cuisine
- June 2011
- Venere Guest
- Couple
- United Kingdom
This was the first yime that we had stayed at an hotel in Luz-St-Sauveur previously we had camped. For the type of hotel this was an excellent choice and good and the owners staff very friendly value for the money. The evening meal was very good
- March 2011
- Venere Guest
- France
This hotel is just at the foot of a hill and is a great spot to stay at. It is not as easily accessible from public transport but is great if coming by car.
- December 2009
- Venere Guest
- Couple
- Spain
Excellent service in a fantastic village! Una estancia agradable y unas vistas maravillosas.
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- September 2012
- Venere Guest
- Family with older children
- France
- March 2012
- Venere Guest
- Couple
- France
Hôtel Ardiden reviews by TripAdvisor
Room Details
Book your pet-friendly accommodation at the 37-room Hôtel Ardiden. Digital TV channels offer entertainment at the end of a busy day. Business travelers will have access to free (wired) high-speed Internet access as well as desks and phones during their Luz-Saint-Sauveur visit. Private bathrooms are outfitted with hair dryers.
Accommodation Services
- Telephone
- Hairdryer in each room
- Desk
- High speed Internet access
How to reach Hôtel ArdidenBy car
A64 motorway, exit "Soumoulou" or "Tarbes ouest" then follow signs to "Lourdes", "Argelès Gazost" and "Luz Saint Sauveur". In the village, follow signs to the thermal baths ("établissement thermal").
Distances from Hôtel ArdidenPont d'Espagne - 10.5 km / 6.6 mi
Hautacam Ski Resort - 11.9 km / 7.4 mi
Col de Tourmalet - 13.7 km / 8.5 mi
Pyrenees National Park - 14 km / 8.7 mi
Pic du Midi de Bigorre - 14.9 km / 9.2 mi
Piau Engaly Ski Resort - 16.6 km / 10.3 mi
Chapel of Templiers - 19.3 km / 12 mi
Gourette Ski Resort - 27.9 km / 17.3 mi
Bigorre Golf Club - 28.5 km / 17.7 mi
Col d'Aspin - 29 km / 18 mi
Col d'Aubisque - 29.5 km / 18.3 mi
Cadeac Watchtower - 29.5 km / 18.3 mi
Chapelle de Pene-Taillade - 29.5 km / 18.3 mi
Church of Cadeac - 29.5 km / 18.4 mi
Church of Saint Exupere - 30.6 km / 19 mi
The preferred airport for Hôtel Ardiden is Toulouse (TLS-Blagnac) - 140.8 km / 87.5 mi.
Distances are calculated in a straight line from the property's location to the point of interest or airport and may not reflect actual travel distance.
Distances are displayed to the nearest 0.1 mile and kilometer.
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Was my first time at a Four Points Sheraton. I signed up for a frequent
visitor card. I thought the free water bottles in the room were an
excellent touch, also the free hot apple cider in the lobby was great.
Similarly, while I did not personally take advantage of it, I loved the
idea of the $5 reimbursement if you did not utilize housekeeping
service. Very smart. In my upcoming travel to nyc and other cities, I
will now always try to stay at a Four Points Shertaon. - Anonymous
Informative staff, great location - Anonymous
location - Luiz
The hotel was perfectly located near to Union Square with a really nice
staff, especially the blond georgian girl. For a 3stars hotel it was
perfect: very clean, very cosy and comfortable. I loved the shower,
it's the first time I'm happy with the bathroom although
I'm traveling all the time and took some 5stars before. There is an
atm machine in the hotel which u can take off money, but it's
limited to not even 200 dollars. There is a map with metrolines
available for free and you have coffee - Anonymous
use internet was great. other than that,it was just somewhere tosleepp - Julie
The view from our room was incredible! The service was great, staff were
friendly; there were some people who truly stood out Gabriella at the
front desk and her manager (whos name I do not recall) who personally
ran up to our room to move the champagne and chocolates (which they very
kindly gave us as an anniversary present) to our new upgraded room,
which we loved. And John Vane (I think thats how you spell it) who works
at the pool bar. Fantastic p[lace to stay, and if you are there in the
s - Anonymous
I loved the rooftop bar! It has a beautiful view of Madison Square Garden and then the world trade towers in the distance. The rooms and hotel were clean and filled with friendly staff and guests. I also loved the selection of complimentary breakfast. It was very convenient for me to grab something quick before leaving. I also loved the huge shower! - Anonymous
The location was perfect for what we were there for. It was so easy to get anywhere from our hotel location. It was right next to the subway station, making it simple to go uptown to downtown and anywhere in between. The staff was very helpful and friendly! We also loved the atmosphere!! The live band downstairs was great (besides the fact that we could hear it in our room the first night). - Anonymous
Great location. Cheap - you get what you pay for. Stay some place else unless you're a kid ona real cheap budget. - Anonymous


text:
Ship Management
Bibby Ship Management Expands
Fast-growing Bibby Ship Management has relocated its Far Eastern and Indian operations to new, larger premises in key strategic locations, ensuring the company is ideally placed to service the needs of its customers worldwide. Bibby Ship Management's new office in India is situated in Mumbai, the heart of Indian seafaring trade and industry. With over 120 members, the Mumbai team assists customers with sourcing and placing Indian seafarers on their ships, technical management of vessels, marine training and business travel. "This move recognises the importance of India as a key training centre for seafarers, particularly in the offshore sector," says Prakash Agarwal, Managing Director, Bibby Ship Management (India) Ltd. "India has earned a reputation as a supplier of high quality seafarers to many of the vessels managed by Bibby Ship Management. Our new Mumbai office, in addition to our locations in New Delhi, Chennai, Kolkota and Cochin, will ensure that we are best placed to build upon that reputation." Bibby Ship Management (Singapore) Pvt Limited has a staff of 11 and is headed by Managing Director Martin Kent and Arvind Mohan, Commercial Director for Asia. "Singapore is one of the largest shipping hubs in the world," says Martin Kent. "With over 5,000 maritime related companies registered here and connections to more than 600 ports in over 120 countries; including Indonesia, Malaysia and China
New Crewing Software for HAV Ship Management
CrewInspector.com an online crew management software provider wins the contract to provide HAV Ship Management Kaliningrad with full crew management solution. CrewInspector will provide online crew management database, integrated online application for seafarers and crew payroll software. Crew management system enables crew managers to create seafarer employment contracts, monitor certificate expiry and organize crew planning across the whole fleet thus reducing manual work
Bibby Appoints Rodden as Regional Managing Director
Bibby Ship Management has recruited a new Regional Managing Director for the UK and Isle of Man, Andrew Rodden, who brings with him commercial and technical knowledge and experience. Andrew Rodden will manage Bibby Ship Management's Crew & Technical service delivery across the U.K. and Isle of Man while managing the support functions and other operational areas within each local business. He will be mainly based in Bibby Ship Management's Aberdeen office.
Lloyd's Maritime Academy, Ship Management
The trend towards outsourcing of ship management services over the past 20 years has created a knowledge gap in shipping companies which once operated a top-to-bottom system to support their fleet. Rodger MacDonald, secretary general of the International Federation of Shipmasters' Associations and course director of the Lloyd's Maritime Academy Diploma in Ship Management says additional education is vital in helping seafarers make the transition to best-of-breed
Graig Ship Management Appoints Callender
Cardiff-based Graig Ship Management has appointed Matt Callender as Operations Director. He joined GSM as General Manager in March and is responsible for the day to day running of GSM's fleet. Callender has thirty-five years experience in shipping, beginning as a sea-going engineer, rising to Chief Engineer, then building a career in management, including a period as Joint Managing Director of Reederei NORD Klaus Oldendorff and General Manager - Technical for OSG Ship Management
NYK Line Hosts Fleet Safety Conference
NYK says it has hosted a safety promotion conference for shipowners and ship-management companies at the NYK head office in Tokyo and at Imabari city in Ehime prefecture. This conference is held during July and August every year as part of the Remember Naka-no-Se safety campaign,which draws on the lessons learnt by the Diamond Grace oil spill in July 1997 to encourage all NYK Group employees to bear in mind the importance of safe operations.
InterManager Announces New Members
InterManager, the international trade association for the ship management industry, has boosted its membership with several new members joining its ranks during the first quarter of this year. Full members joining include ship management company Nigeria LNG and crew manager Nedcon. They are joined by Associate members KVH, Cubisol, Jadran Pismo and Stark Moore Macmillan. Speaking as the InterManager Executive Committee Meeting in Athens today (June 7) InterManager President Alastair Evitt
Nakilat Chooses Shell to Manage LNG Fleet
Qatar Gas Transport Company (Nakilat) has appointed Shell International Trading and Shipping Company Limited to manage its fleet of 27 new liquefied natural gas carriers in a 25-year deal, according to a report on www.gulfnews.com. Under the arrangement it is expected that operational management will be transferred to Nakilat within 12 years, the report said. Shell will provide a range of shipping services to Nakilat including ship management as well as the transfer of know-how and
Crowley Forms New Technical Services Business Unit
Crowley Maritime Corporation has formed a new non-asset, knowledge-based Technical Services business unit that will bring together the company's vessel construction and naval architecture, government services and ship management services. Crowley veteran Steve Collar has been appointed senior vice president and general manager of the enterprise. He will continue to work from the company's headquarters in Jacksonville and report to Tom Crowley, chairman, president and CEO.
Monjasa DMCC to Implement GL ShipManager System
Monjasa DMCC, a bunkering specialist, has chosen to implement the GL ShipManager system to optimize and streamline its ship management practices. Monjasa operates a fleet of 18 vessels, delivering fuels and lubricants to their customers around the globe and will implement the system onboard and onshore. Monjasa will implement the software to maximize the efficiency of its technical, quality and safety management processes as well as its crewing and procurement administration.
Sino-Global Purchases First Tanker
Sino-Global Shipping America, which was recently listed on Nasdaq, is becoming a shipowner. The shipping agency, logistics and ship management services company today announced that it has signed a Letter of Intent to acquire a small oil/chemical tanker from Rong Yao International
SHIPPINGInsight 2015 Set for October 13-14
SHIPPINGInsight 2015 to take place October 13-14 in Stamford, Conn. The annual technical symposium, exhibition and networking event for maritime industry professionals in North America, SHIPPINGInsight 2015 Fleet Optimization Conference & Exhibition, will take place Oct
ABB to Power Tallink's LNG Ferry
ABB has won an order to deliver complete electric power plant, electrical propulsion systems and an energy management solution for Estonia-based Tallink Grupp´s new liquefied natural gas (LNG) powered fast ferry. The large-scale ferry will be built at Meyer Turku shipyard in Finland for
LISCR Appoints New Managing Director for Hong Kong
The Liberian Registry has appointed shipping executive Gerry Buchanan as managing director of its dedicated Hong Kong office, the registry announced today. As the recently retired president of Genco Shipping & Trading
Crowley Crew Aids Ill-fated Catamaran
The crew of the Crowley-managed, 393-foot, heavy lift vessel Ocean Crescent recently provided assistance to five people aboard the damaged and drifting catamaran Rainmaker during a routine transit from Progresso, Mexico, to Halifax, Canada.
Ulstein Verft Delivers 'Blue Queen'
On 24 February 2015, 'Blue Queen' a platform supply vessel of the PX121 design, was delivered to Blue Ship Invest from Ulstein Verft. This vessel is the first of two for which Norway-based Golden Energy offshore is awarded the ship management contract.
Ulstein Delivers PSV Blue Queen
Platform supply vessel (PSV) Blue Queen, of Ulstein's PX121 design, was delivered to Blue Ship Invest from Ulstein Verft on February 24, 2015. This vessel is the first of two for which Norway-based Golden Energy offshore is awarded the ship management contract.
Five More Tankers under Crowley Management
Crowley Accord Management Pvt. Ltd., the international ship management venture managed globally by Crowley Maritime Corp.'s ship management group, was awarded full technical management contracts for five new tankers. These tankers will be joined in the coming weeks by three more
Bibby Sees Hike Interest From Offshore Sector
Bibby Ship Management is seeing a near 20% increase in inquiries for its services from the offshore sector as ship owners and support vessel operators look to reduce costs and recruit the best crews for their vessels. This development is fuelled in part by a move by the oil majors to reduce
Shanghai's Pudong Shipping Hub is Bullish
Shanghai's Pudong New Area has made progress in building an international shipping center last year and the opening-up reforms in the city's free trade zone (FTZ) have lured another six global ship management firms to dock there, reports Shanghai Daily.
German Company Pleads Guilty to AK Bilge Dumping
German shipping company AML Ship Management GMBH and one of its chief engineers pled guilty yesterday to illegally discharging oily waste in Alaskan waters last August. The company and Nicolas Sassin, 45, the chief engineer of AML's City of Tokyo vehicle carrier
Seminar Addresses Marine Vibro-Acoustics
As the International Maritime Organization (IMO) furthers measures for controlling onboard noise and vibration levels in the interest of passengers and seafarers' health, it has become increasingly important for the shipyards and design houses to understand the deeper sciences related to the
BSM Takes Management of Two SOVs
BSM is to take on the ship management of two new ULSTEIN SX175 Service Operation Vessels (SOVs), ordered as part of a WINDEA joint venture involving its parent company Bernhard Schulte. Both vessels are to be built at the Ulstein Verft shipyard in Norway and will be operated by Bernhard Schulte
Swire Pacific Welcomes PSV, Pacific Liberty
Shipowner and operator, Swire Pacific Offshore Operations (Pte) Ltd (SPO) welcomed its fourth L Class Platform Supply Vessel (PSV), Pacific Liberty at a naming ceremony held in Kyoto, Japan on Tuesday, 3rd February 2015. The naming ceremony was held at Maizuru Shipyard of Japan
THOME Group's Junior Officer Recruitment Now Self-Sufficient
THOME Group's Junior Officer Recruitment Now Self-Sufficient International ship management company THOME Group has become self-sufficient in recruiting junior officers, the company announced today, saying it managed to fill all of its 2014 junior officer vacancies from within its own pool of


text:
I am having an issue with my sql query.
create table rental
rental_id NUMBER(5) NOT NULL,
rental_date timestamp NOT NULL,
inventory_id NUMBER(5) NOT NULL,
customer_id NUMBER(5) NOT NULL,
return_date timestamp NOT NULL,
staff_id NUMBER(5) NOT NULL,
constraint rental_primary PRIMARY KEY (rental_id),
constraint rental_foreign FOREIGN KEY (inventory_id) REFERENCES
constraint rental_foreign2 FOREIGN KEY (customer_id) REFERENCES
constraint rental_foreign3 FOREIGN KEY (staff_id) REFERENCES staff(staff_id),
constraint rental_unique_rental_date unique (rental_date),
constraint rental_unique_inventory_id unique (inventory_id),
constraint rental_unique_customer_id unique (customer_id),
constraint rental_rental_date check(to_char(rental_date,'YYYY/MM/DD HH:MI:SS AM')
between '2005/01/01 00:00:01 AM' AND '12/31/2015 11:59:59 PM'),
constraint rental_return_date check(to_char(return_date,'YYYY/MM/DD HH:MI:SS AM')
between '2005/01/01 00:00:01 AM' AND '12/31/2015 11:59:59 PM')
when I am trying to insert data, It is throwing this error "ORA-01843: not a valid month". Can anyone please suggest me what type of datatype can I use for rental_date and return date to get through this situation? Here is my sample data which I am trying to upload
rental_date return_date
Note : I can see this type of format in my excel sheet where I have my data but when I get error
"ORA-01843: not a valid month
Row 145: 144, 2011-05-25 23:49:56 ,1689,357, 2011-06-01 21:41:56 ,2"
I am observing different format of time here.
Can anyone suggest me a solution?
Thanks in advance.


text:
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(4)Hello Melinda Because he retires does it also mean the practice is ending??? No exchange of hands etc? Get a couple of young motivated PA'S to carry the
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Home > Home > Home Decor
Home Decor
If Brookstone products fit how you live, our home decor products will fit where you live–adding a unique flair and practicality to any personal space, large or small. So check out our home furnishings, pillows, art, accents and seasonal styles. Then make yourself at home.
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