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Spotted on Rippedbackpocket, Aron Maiden is effortlessly cool in scuffed boots, leather jackets and unexpected accessories. Aron's mom (shown in the top photo) named him after Iron Maiden.
ABOUT WGSN kids
Little people are big business. Get inspiration from emerging labels, hot websites and the mini-trendsetters that are changing kidswear culture. The kid's hour is all day long.More about WGSN >


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Michael King
Retired actor and puppeteer Michael King, 69, died at his home in Tarzana June 1.
Retired actor and puppeteer Michael King, 69, died at his home in Tarzana June 1.
Dean and Carol Sanderson, a boy, Ryan David, Nov. 24, Methodist Hospital, Arcadia. Father's a credit specialist for Daily Variety; mother is non-pro.
Barbara Cohen, the award-winning author of more than 30 children's books including "Molly's Pilgrim," died Nov. 29 at her Bridgewater, N.J., home.
Former TriStar production topper Stephen Randall has been hired as president of the new, deep-pocketed development company Cinema Line Films.
Thomas H. Cannan Jr., senior administrator of production services for the Screen Actors Guild, died of cancer Nov. 29 at his home in Westlake Village. He was 58.
Meg Marguiles and Gregory Lipstone, Sept. 19, Brentwood. Bride's a freelance production associate; groom's a television packaging agent for the William Morris Agency.
Joanne Burns, VP of research for Buena Vista TV, has been promoted to supervise research for the studio's network television arm as well. Burns joined the studio as exec director of research in 1989…
Dale McBride, a veteran country music entertainer and father of country star Terry McBride, died Nov. 30 from a brain tumor. He was 55.
John I. White, the voice of the singing Lonesome Cowboy of the NBC radio show "Death Valley Days," died Nov. 26 of heart disease. He was 90.
Clem Beauchamp, a stuntman/production manager and one of only a handful of assistant directors to win an Academy Award, died Nov. 14 in Santa Rosa of natural causes. He was 94.

subset: commoncrawl


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Little noise at high ISO settings. Image stabilization. Optical viewfinder. Antireflective LCD.
Function button is flat and hard to find by touch. Wide-angle lens is not as wide as the SD1000's.
The PowerShot SD1100 IS adds a few new features to its Editors' Choice predecessor, but the SD1000 still can't be beat in terms of image quality and shooting flexibility.
When you're finished watching the video, read our full review of Canon PowerShot SD1100 IS.
Canon PowerShot SD1100 IS Video Review
Canon's newest, highly anticipated PowerShot is a pretty awesome camera, but it didn't quite get our Editor's choice. Find out why.
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Zathura: A Space Adventure
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Watch Zathura: A Space Adventure Online
Release:November 11, 2005
RunTime:1 hr 53 min
IMDB Rating:6.1/10 (47995 votes)
Director:Jon FavreauActors:Jonah Bobo, Josh Hutcherson, Dax Shepard, Kristen Stewart, Tim Robbins(View All)
Description: Watch Zathura: A Space Adventure full movie online for free directed by Jon Favreau produced in 2005. Genres are Action, Adventure, Comedy, Family, Fantasy, Sci-Fi.
To watch movies, Get the Flash Player to view this trailer.
Fatal error: Allowed memory size of 33554432 bytes exhausted (tried to allocate 13388115 bytes) in /home/star10/public_html/cache-credits/Zathura_A_Space_Adventure_2005.php on line 1


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Bridge Street
All Lanes Reopen On I-95 NB After Truck Overturns Near Bridge Street
The incident was reported around 9:30 a.m. Wednesday on I-95 northbound near Bridge Street.
Accident Closes Two Lanes On I-95
An accident this morning is causing trouble for commuters.
Philadelphia Officer Injured In Frankford Car Accident
Authorities say a Philadelphia Police officer was injured in a car accident Sunday evening in the Frankford section.
Tractor Trailer Crash Creates Traffic Nightmare Along I-95
Shortly before 3:30am on Tuesday, a tractor trailer headed south on I-95 overturned near Bridge Street.
Cash Stolen From Northeast Philly 7-Eleven
Police are looking for the man they say robbed a 7-Eleven in the Bridesburg section of Philadelphia early Thursday morning.
19-Month-Old Hospitalized After Fall From Window In Summerdale
It happened around 7:30 p.m. Friday in the 900 block of Bridge Street.
PennDOT To Host Open House Meeting About I-95 Improvements
PennDOT will host an open house public meeting on Thursday, October 10th from 6 p.m. to 8 p.m. to present plans to improve I-95 from Wheatsheaf Lane to Levick Street and to extend Adams Avenue in Philadelphia.
Officials Investigate Serious Crash Involving Car, Motorcycle In Philadelphia
Officials are investigating a crash involving a car and motorcycle in Philadelphia.
Two Arrested After Strong-arm Robbery In Lambertville
Police say they received a call about an attempted purse-snatch on Bridge Street shortly before 9 a.m.
Delivery Truck Stolen In Northeast Philadelphia
Philadelphia police are searching for the suspect who stole a delivery truck in Northeast Philadelphia early Tuesday morning.
Multi-Vehicle Crash On NB I-95 Near Cottman Avenue
State polie say it was caused by a disabled vehicle in the right lane.
Fire Breaks Out In Philadelphia Residence
The fire happened around 5:30 p.m. at a house at 861 Bridge Street.
I-95 Northbound Reopens After Tractor Trailer Accident
Interstate 95 northbound has reopened after an overturned tractor trailer snarled traffic for hours Thursday afternoon.
3-Alarm Fire Breaks Out At Phoenixville Auto Parts Store
Authorities in Chester County are investigating the cause of a three-alarm fire that broke out at an auto parts store Sunday evening.
Man Struck, Killed By SEPTA Bus In Frankford
A man died after being struck by a SEPTA bus in Northeast Philadelphia early Thursday morning.


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1. Preheat the oven at 350° F.
2. In a baking pan place the bread crumbs.
3. Stir the garlic into the melted butter. Drizzle the melted butter over the crumbs. Add in the Parmigiano-Reggiano. Toss well with a spoon and set aside.
4. In a heavy-duty 3-to-4 quart saucepan, add in the butter and melt.
5. Whisk in the flour and continue to whisk over low heat for 3 to 4 minutes.
6. Slowly add in the milk, whisking constantly. Whisk until the sauce is smooth and slightly thickened.
7. Raise the heat to medium and bring the sauce to a simmer, whisking constantly.
8. Lower the heat to maintain a gently simmer and cook, whisking occasionally, for 10 minutes.
9. Remove the sauce from the heat and gently whisk in both the cheeses.
10. In large bowl add in the macaroni, white sauce, ham and peas. Mix well with the spatula.
11. Transfer the mixture to a 9-x-13 baking dish, top with the crumb mixture and bake for 15 minutes.
12. Serve Macaroni & Cheese with green salad.


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OMG, Are these spider mites?
Just found this on a Philodendron Bipinnatifidum plant. It has been summered outside. I put the whole leaf in a bag and taped it tight.
I also see a lot ants on my another tree - a Schefflera Arboricola, it is not at the same place where the Philo is. Read about Ants harvest the honeydew of Spider Mites?
Any tips to get rid of them if they are what I think they are?
Those don't look like spider mites. I believe spider mites are so small, you need a magnifying glass to see. They're odd looking whatever they are though.
I think the honeydew you're thinking of is scale, not spider mites (I could be wrong though). I've had scale and saw ants on the plants that had it.
This post was edited by plantomaniac08 on Thu, Jun 12, 14 at 20:25
I can't enlarge the size of the pictures on my Kindle, but I'd goess that they are freshly hatched spiderlings. You should let them go in your garden immediately.
Examine your schefflera for small brown scale insects on the foliage and stems. Scale are honeydew producers, especially on many of the most common houseplants. Put infested plants outside for awhile and the ants will find them.
I'm pretty sure they're baby Argiope spiders, known as common, yellow, or golden garden spiders. They are a beautiful sight to see, especially large ones. Not to rain on your parade, but yeah, you exterminated some good guys. You live and learn my friend.
These are common garden spiders. The ones that travel all over your yard and put up webs that catch you when you are walking through your yard. I always try to get rid of as many of these as possible. I hate the feel of running into a web and knowing that a large spider is on me somewhere.
Yeah, as others have said, you annihilated a bunch of baby good guys. Right after emerging from an egg sac, the slings tend to congregate for a couple days before moving on.
Clarification on spider mite ID ... spider mites are very small -- perhaps about the size of a period (.) and really are reddish as opposed to true red. They tend to move very slowly. Should you come across some fast moving buggers that are screaming bright red in color, leave them alone. They are predatory mites and you want those around.


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We hope that we will live only because we must be with God, as alive as He is.
Sorin Cerin
Source: Wisdom Collection
Contributed by: lorasmith
Nobody will ever be able to understand the meaning of the measure of his own words.
Do not rummage through your thought's drawer because you will be ever more disorientated than they are.
Has anyone succeeded in being his own desire?
Has anyone succeeded in being his own desire?
Do not walk away from death because you came out of it.
Who can believe in illusion even if we all live the Illusion of Life?
Do not be to yourself more that God may be to you.
What shell did not feel the sound waves and which bird did not face at least once the wind?
No tiredness can destroy hope like death can, as the absolute fatigue of life.
Copyright © 2015 Gaiam, Inc.


text:
Ecometer is an OBD-II CAN plug-and-play fuel economy instrument, providing vehicle operators critical instantaneous miles-per-gallon feedback and average fuel economy readings. It installs in less than one minute and operates on all 1996 model year and newer OBD-II CAN vehicles.
Auto Meter Products Inc
[Booth 2451]
Fleets, Trucks and Accessories
Fuller Advantage Series transmissions deliver weight savings and fuel efficiency...
Public Works Staff
Optional Active Bouncing Control (ABC) feature prevents operators from damaging the...
Please read our Content Guidelines before posting.
Copyright ©
2015 Hanley Wood Media, Inc. All rights reserved.


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Google today announced the ability to view and manage photos and videos in both Google+ and Google Drive. Previously you were limited to managing photos and videos within Google+. While this new feature is not yet live everywhere Google's help page details that if you delete a photo/video in Google Drive it will also be removed from Google+ (and vice versa). One …Read more
Category: News
Get in Line: 'Halo 5: Guardians' Release Date Revealed!
One of the most anticipated Xbox One exclusive video game releases of this year now has a release date. Published by Microsoft Studios and developed by 343 Industries, the first-person shooter game Halo 5: Guardians will be the sixth installment in the popular game series featuring the Master Chief along with the new Spartan Locke character who appeared in the live action series Halo: Nightfall.Read more
Block Buster Saturdays: Movie Trailers You May Have Missed This Week
It looks like we're headed to a Block Buster year at the movies! We started the week with a movie trailer for Mission:Impossible – Rogue Nation, and it seems as if 2015 is going to be a GOOD year to grab yourself some popcorn and enjoy the silver screen.Read more
Slack Got Hacked
Current multi-billion dollar valuation media darling of the month – Slack – just announced "unauthorized access to a Slack database storing user profile information". In other words, Slack was hacked. According to a post, a small number of accounts showed suspicious activity and those users were notified. In response to the hack, Slack has created a two factor authentication option.Read more
Could a Jailbreak for iOS 8.2 Come This Saturday?
A little over a week ago, Apple pushed their iOS 8.2 update to the public, and many jailbreakers, including myself were left wondering if we would see Cydia on our iDevices if we updated.Read more
#SeedShare Is Not Only a Hashtag, It's Now a Legal Movement in D.C.
Well, it may be one thing that a lot of people dislike, but they have had to learn to accept in the last month: Marijuana in Washington D.C. is legal, and #SeedShare is now a thing.Read more
CNNgo Is the Latest Channel for Apple TV
Earlier this week, CNN announced that Apple TV would be gaining their CNNgo app channel. On Wednesday, Apple silently pushed an update to their Apple TV with the CNNGo app, that taps into the CNNgo service (which requires a subscription to a pay-tv partner).Read more
Apple App Store App of the Week: Tangent
Every week Apple picks a new app of the week to feature in their App Store. The App of the week of March 26th is photography app Tangent. Normally priced at $1.99, Tangent is now available for the low, low price of free.Read more
Google Wants You to Pay Your Bills Through Their New Gmail Pony Express
In another experiment from Google that may or may not (but more than likely will) eventually kill off, the search engine is reportedly building a new service for their Gmail Pony Express. The service is being called "Pony Express', which will let Gmail users pay bills, as well as split the costs of items with fellow Gmail users.Read more
Apple Starts Releasing 3rd Party Apple Watch Apps
With Apple's latest creation the Apple Watch to be released in less a month on April 24th, developers have been hard at work creating updates to their apps to make them compatible with the new smartwatch. And before you can even get your hand on one, some apps are already showing up.Read more
Roku Announces New Smart TV Lineup with Sling TV & WatchESPN
One of my favorite devices that I use in my home is my Roku. Even though I have a Smart TV, I was actually pretty disturbed that Roku TV was not on my Sony Vizio when I purchased it. So I was surprised when I found out a lesser known (in the US) brand by the name of TCL announced …Read more
Pre-Order the Samsung Galaxy S 6 and S 6 Edge Starting Tomorrow!
There's no doubt that Samsung stole the show at MWC with their new Samsung Galaxy S 6 and S 6 Edge smartphones. As is usually the case after a major announcement, there was a bit of a wait before orders could be placed; that changes on March 27th when preorders can be placed and nationwide availability will be April 10th. The …Read more
Can't Resist Pixel Art? New WITTI Smart lights Might Be Your Fix
There's no shortage of smart gadgets that are for made for everyday use nowadays. For those of you all that are looking to make your home more smartphone friendly, Hog Kong startup WITTI has released NOTTI and DOTTI, two of their interactive smart lights for Android and iPhone devices.Read more
Twitter Releases Periscope, Their Answer to Live-stream App Meekrat
If you haven't heard, live-streaming is the hottest thing to do these days. With apps like Meekrat making noise in the social app world, it's no surprise that Twitter would not have their hands in the pot. Less than two weeks ago, Twitter purchases streaming startup Periscope and has now repackaged it as their own app, available today.Read more
Amazon Cloud Drive Goes Unlimited; Your Move, Dropbox
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IK Multimedia Unveils UltraTuner for Android
Just over a year ago, IK Multimedia released UltraTuner for iOS devices, and my review summed up "It's the Best iOS Tuner Available." Between the accuracy, easy visibility and simple usability, there is no other tuner I have needed since. Now IK Multimedia has released UltraTuner for Android, allowing anyone with Android 4.1 or later to get in tune!Read more
Taylor Swift's Music Is Streamable, Just Not on Spotify
As of Yesterday, it seems as if Taylor Swift is streaming music again. Thanks to Aspiro Service's Tidal Streaming Media site, about 17 thousand subscribers to the service get the luxury of hearing her tunes.Read more
Throw That Stylus Away! The Neo SmartPen N2 Is Everything You Need
While I was browsing the web this morning, an interesting gadget caught my eye, so I had to talk about, the Neo Smartpen N2. Originally a Kickstarter program, the startup raised over 70,000 in less than a month.Read more
2K Games Having a Huge Game Sale on the iTunes App Store!
2K Games does things a little differently on the iPhone and iPad – rather than watered-down 'lite' versions of games, they port the full versions from PC/console. And from now until April 3rd they are having a huge sale on five of these games up to 80% off! Classics such as Bioshock and XCOM: Enemy Within are must-buy games!Read more
'The Legend of Zelda Symphony of the Goddesses' Concert Tour Dates Expand
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Vessel's New Streaming Service Launches with a One Year Free Subscription
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Letters From the South: Busan Review
The Bottom Line
An uneven but contemplative collection of migrant tales.
A Window on Asian Cinema, Busan International Film Festival
Lee Kang-sheng, Lulu Huang, Wu Kexi
Aditya Assarat, Royston Tan, Midi Z, Sun Koh, Tan Chui Mui, Tsai Ming-liang
In a portmanteau of six short films, Southeast Asian filmmakers explore the links between the Chinese diaspora and the Middle Kingdom itself.
Letters are only meaningful when they are meant to be two-way communication – and the significance of the six shorts in the omnibus film Letters from the South could be gauged by their abilities to contemplate the ever-shifting relationship between the Chinese diaspora ("the South") and China (the roots in "the North"). Posting a mix of melancholic and comic questions, this Malaysian-produced portmanteau offers substance rendered in a range of styles, and will inevitably be of interest to film programs examining either China or migration issues.
The six shorts could be roughly divided into three groups: the first pair, Aditya Assarat's Now Now Now and Midi Z's Burial Clothes sees different generations casting glances northwards. Assarat's Thai-Chinese schoolgirl reflects on how her mainland Chinese cousin has transformed herself from a shy nobody into her current alluring, artistic self; for the Myanmar-Chinese director Z, it's all about the hopes of returning home, as a granddaughter helps realize his grandfather's final wishes by bringing the funereal attire he left in his ancestral village back in China.
Meanwhile, Singaporeans Sun Koh and Royston Tan offer tales closer to home. The former's New New Panda using a pending Chinese takeover of a Singaporean radio station to reflect on how one of its veteran production staffers positions himself culturally; the latter's Popiah, which looks at how kinship is fostered through traditional cooking.
The final two episodes are leaps into fantasy: in a whirl of quick edits of nocturnal images in the titular Malaysian city, Tan Chui Mui's A Night in Malacca reflects on the possibility of revisiting the nostalgic sentiments of exiled Chinese writer Yu Dafu; as he described how memories subside in the tropical Southeast Asian heat.
But at least Tan's conversing with someone or something with her entry: the same couldn't be said of Malaysian-born Tsai Ming-liang's Walking on Water, which is nothing more than a love letter to his hometown of Kuching. It's a shame the film ends with a letdown since the what comes before shapes up to be a contemplative collection of affecting migrant tales.
A Window on Asian Cinema, Busan International Film Festival
Production Company: Da Huang Pictures
Directors: Aditya Assarat, Royston Tan, Midi Z, Sun Koh, Tan Chui Mui, Tsai Ming-liang
Cast: Lee Kang-sheng, Lulu Huang, Wu Kexi
In Thai, Mandarin, Teochew, Cantonese and English
105 minutes
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Growing Friends' plant sale – 28 and 29 MarchLearn More
Our Locations
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- Birdwood Avenue,
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Take a traditional punt cruise on Ornamental Lake and float around its... read on
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Books and much more for low prices
Courtland Books and More sells qualaity books, dvd, and other fine merchandise at discount prices.
Currently reselling mainly DVD's on Amazon. I also sell books, new or used. I will be starting my own ecommerce site within the next 6 months.
Provoking Thoughts and Expanding Horizons since 1992 We offer an interesting mix of books, herbs, and supplies for many spiritual paths and health needs.
Reseller of Books, DVDs, Electronics, Pet Supplies, Toys & More!
we sell books ,dvds and adult dvds,and misc stuff
online seller of books, toys and gifts
online store on Amazon.com
We are a business located in Greensboro, North Carolina that sells a variety of wholesale products and used books.
Online bookstore and unique gift store. Specialty basket gifts will be created by order.
Phoenix Book Recycling started out as a small local book recycling and reselling company. In the past 2 years we have increased our ability collect and recycle books and have begun selling other products beyond books.
I am an individual retailer. I own a bundle of websites and also specialize in reselling by means of drop-shipping.
Wholesale display business
Tellurian Book Production, is a leader in Diary manufacturing located in the United Arab Emirates, Dubai, specialized in manufacturing diaries, note books, note pads, wall and desk calendars and desk planners amongst other products for the corporate envir ...
Phoenix Book Recycling was founded in 2012 in Quincy, Massachusetts. We began as a small book redistribution company, collecting unwanted books from friends, neighbors and environmentally conscience citizens from all over Massachusetts, New Hampshire and ...
East Africa Safari Bookers is a tour company based in Nairobi - Kenya offering travel packages in Kenya and Tanzania. With over 10 years of practice, we have developed our clientele worldwide with good company reputation and reviews.Our packages include K ...
Selling books and toys on Amazon


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Download the Free Unbound MEDLINE PubMed App to your smartphone or tablet.
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buprenorphine [keywords]
5100 results
- Recognizing potential buprenorphine medication misuse: product packaging does not degrade with laundering. [JOURNAL ARTICLE]
- Subst Abus 2015 Mar 26.:0.
Expanded office-based buprenorphine opioid dependence treatment is associated with medication misuse and diversion consequences. Recurrent early refill requests may indicate misuse or diversion, though further research is needed on how to effectively recognize and address the issue in clinical practice. In the current study, patient report of damaged medication from laundering prompted evaluation of laundering on degradation of buprenorphine-containing product packages and contents.Four buprenorphine-product packaging approaches were assessed: three buprenorphine/naloxone placebo demonstration products (Suboxone(→) and Bunavail(→) film in foil wrappers, and Zubsolv(→) tablet in a blister pack), and Rexam-manufactured Screw-Loc(→) closure pill container filled with a chewable aspirin as a surrogate for generic buprenorphine and buprenorphine/naloxone products. Two experimental laundering conditions, wash machine alone (W) and washer/dryer (W+D), were compared to unlaundered control (C) condition. Standard laundering settings were based on patient presentation. Products from the two experimental and control conditions were labeled A, B, or C with counterbalanced assignment prior to visual examination of packaging and contents by the investigator who was blinded to condition.Packaging and contents remained intact for all products across experimental conditions with only minor cosmetic effects compared to control. The W+D Suboxone film had 1-2mm curling of the wrapper corners. Zubsolv blister packs had slight paper label fading (W+D > W). Bunavail W+D foil had an indentation outlining the inner film. The W+D bottle tablet had a ˜1mm nick on one edge. No other differences were noted. After implementing more structured treatment and reviewing the results with the patient, he endorsed fabricating the laundering story to get additional medication.Laundering is an unlikely cause of damaged buprenorphine-containing medication packaged in foil wrappers (Suboxone(→), Bunavail(→)), blister pack (Zubsolv(→)) or prescription pill bottle (generic buprenorphine or buprenorphine/naloxone products). Patient reports of such may indicate medication misuse or diversion.
- UHPLC-MS/MS quantification of buprenorphine, norbuprenorphine, methadone, and glucuronide conjugates in umbilical cord plasma. [JOURNAL ARTICLE]
- Biomed Chromatogr 2015 Mar 22.
Opioid use during pregnancy can result in the newborn being physically dependent on the substance, thus experiencing drug withdrawal, termed neonatal abstinence syndrome (NAS). Buprenorphine and methadone are two drugs used to treat opioid withdrawal and are approved for use in pregnancy. Quantification of these compounds in umbilical cord plasma would help assess in utero exposure of neonates in cases of buprenorphine or methadone use during pregnancy. An LC-MS/MS method using solid-phase extraction sample preparation was developed and validated for the simultaneous quantification of methadone, buprenorphine, norbuprenorphine, and glucuronide metabolites in umbilical cord plasma. The average accuracy (percentage error) and precision (relative standard deviation) were <15% for each validated concentration. Our data establishes a 2 week maximum freezer storage window in order to achieve the most accurate cord plasma concentrations of these analytes. Additionally, we found that the umbilical cord tissue analysis was less sensitive compared with analysis with umbilical cord blood plasma, indicating that this may be a more appropriate matrix for determination of buprenorphine and metabolite concentrations. This method was successfully applied to the analysis of cord blood from women with known buprenorphine or methadone use during pregnancy. Copyright © 2015 John Wiley & Sons, Ltd.
- Quantification of morphine, morphine 6-glucuronide, buprenorphine, and the enantiomers of methadone by enantioselective mass spectrometric chromatography in whole blood. [JOURNAL ARTICLE]
- Forensic Sci Med Pathol 2015 Mar 24.
Deaths among drug addicts are frequently caused by intoxication with methadone and/or morphine. These drugs are often used in combination with other drugs, such as buprenorphine. In addition, methadone is generally used as a mixture of R- and S-enantiomers. To date, a method for separation and quantitation of these specific drugs has not been developed. The aim of this study was to develop a sensitive enantioselective method for quantitation of morphine, its active metabolite morphine 6-glucuronide, buprenorphine, and R- and S-methadone, in a single analytical run.Whole blood samples were diluted with 0.5 mol/L ammonium carbonate buffer and extracted on a Bond Elut C18 solid-phase extraction column with an automatic solid-phase extraction system. Chromatographic separation was performed on a chiral alpha-1-acid glycoprotein column with an acetonitrile/ammonium acetate buffer (10 mmol/L, pH 7.0, 22:78 v/v) mobile phase. The whole blood concentrations of the drugs were quantified by mass spectrometry using their stable isotope-labeled compounds as internal standards.The method was validated with respect to specificity, linearity, precision, limits of detection, and quantification and matrix effects. The precision (coefficient of variation) was below 15 %, and the accuracy was between 90 and 115 %.This method will be useful for routine analyses in forensic laboratories where blood samples are frequently analyzed for drugs of abuse. In some cases, sudden death from methadone overdose is caused by the enantiomeric form of the methadone, which makes the enantiomer separation capability of this method important.
- Analgesia in mice with experimental meningitis reduces pain without altering immune parameters. [JOURNAL ARTICLE]
- ALTEX 2015 Mar 24.
Intracranial lymphocytic choriomeningitis virus (LCMV) infection is a widely used animal model to study virus-induced cytotoxic T cell (CTL) mediated meningitis and immunopathology. Nevertheless, this model causes severe pain and distress in mice, especially at later stages of the disease. Therefore, new treatment regimens to improve animal welfare have to be developed. In this study, we subcutaneously implanted ALZET® osmotic pumps continuously releasing buprenorphine to reduce pain in mice with LCMV-induced meningitis. Thereby, mice treated with buprenorphine demonstrated strongly reduced symptoms of pain. However, the LCMV-specific cytotoxic T cell response and the immune cell infiltration into the central nervous system (CNS) were unchanged in analgesia treated mice indicating that the LCMV-induced immune response was not altered in these mice. Taken together, we demonstrate that in this animal model for meningitis continuous buprenorphine treatment improves animal welfare without affecting the immune response.
- Interpretation of Urine Drug Testing Results in Patients Using Transdermal Buprenorphine Preparations for the Treatment of Chronic Noncancer Pain. [JOURNAL ARTICLE]
- Pain Med 2015 Mar 20.
To determine whether the prevailing liquid chromatography and tandem mass spectroscopy assay (LC-MS/MS) assay designed to monitor buprenorphine compliance of the sublingual formulation used in the substance abuse treatment setting can be extrapolated to the transdermal formulation used in the chronic pain treatment setting, which is 1000-fold less concentrated.Retrospective chart review SUBJECTS: Self-reported compliant patients using the transdermal or sublingual formulations of buprenorhphine. Transdermal patch application was also visually confirmed during clinic visits.Urine drug test results from a LC-MS/MS were compared between samples from transdermal and sublingual patients.While all sublingual patients tested positive for at least one metabolite of buprenorphine, only 69% of the transdermal patients did so. In addition, the most abundant metabolite in the transdermal patients was buprenorphine-glucuronide, as compared with norbuprenorphine-glucuronide in sublingual patients.These data suggest that currently available urine drug tests for buprenorphine, including the more expensive LC-MS/MS based assays, may not be sufficiently sensitive to detect the metabolites from transdermal buprenorphine patients. This study highlights the need to evaluate the value and sensitivity of urine drug tests given the wide range of buprenorphine dosing in clinical practice. These results underscore the need for additional cost benefit analyses comparing different confirmatory drug testing techniques including many commercially available drug testing options.© 2014 Wiley Periodicals, Inc.
- Effect of buprenorphine on total intravenous anesthetic requirements during spine surgery. [Journal Article]
- Pain Physician 2015 Mar-Apr; 18(2):E261-4.
- AbstractPublisher Full Text
Buprenorphine is a partial mu receptor agonist and kappa/delta antagonist commonly used for the treatment of opioid dependence or as an analgesic. It has a long plasma half-life and a high binding affinity for opioid receptors. This affinity is so high, that the effects are not easily antagonized by competitive antagonists, such as naloxone. The high affinity also prevents binding of other opioids, at commonly used clinical doses, to receptor sites - preventing their analgesic and likely minimum alveolar concentration (MAC) reducing benefits. This case report contrasts the anesthetic requirements of a patient undergoing emergency cervical spine surgery while taking buprenorphine with anesthetic requirements of the same patient undergoing a similar procedure after weaning of buprenorphine. Use of intraoperative neurophysiological monitoring prevented use of paralytics and inhalational anesthetics during both cases, therefore total intravenous anesthesia (TIVA) was maintained with propofol and remifentanil infusions. During the initial surgery, intraoperative patient movement could not be controlled with very high doses of propofol and remifentanil. The patient stopped moving in response to surgical stimulation only after the addition of a ketamine. Buprenorphine-naloxone was discontinued postoperatively. Five days later the patient underwent a similar cervical spine surgery. She had drastically reduced anesthetic requirements during this case, suggesting buprenorphine's profound effect on anesthetic dosing. This case report elegantly illustrates that discontinuation of buprenorphine is likely warranted for patients who present for major spine surgery, which necessitates the avoidance of volatile anesthetic and paralytic agents. The addition of ketamine may be necessary in patients maintained on buprenorphine in order to ensure a motionless surgical field.Buprenorphine, anesthesiology, intraoperative, total intravenous anesthesia, pharmacology.
- Fabrication and statistical optimization of a polysaccharide-based sublingual film of buprenorphine hydrochloride for breakthrough pain management: in vitro and in vivo performance. [Journal Article]
- Drug Deliv Transl Res 2014 Apr; 4(2):116-25.
- AbstractPublisher Full Text
A typical breakthrough pain episode is severe, categorized by a fast onset, typically reaches peak intensity instantly, and lasts for an average duration of about 30 min. The research work includes the use of opioid for the treatment of breakthrough pain with special emphasis on the development of rapidly dissolving sublingual film formulation of buprenorphine hydrochloride (BPH). BPH is an opioid analgesic with low oral bioavailability due to less absorption and first-pass metabolism. The clear and transparent sublingual films were prepared using a film-forming polymer (pullulan) with a plasticizer (PEG 400). The formulation was optimized statistically using 3(2) randomized full factorial design. The optimized film formulation showed desired mechanical properties (tensile strength of 25 N/m(2)) and a minimum disintegration time of 16 s. Differential scanning calorimetry and X-ray diffraction studies confirmed the uniform distribution of the drug in polymeric matrices. Morphological study showed the absence of drug crystals on polymeric surface. The relative bioavailability of the film formulation was increased by 10 % with respect to tablet formulation due to rapid T max (0.08 h for film while 0.15 h for tablet), which was confirmed by in vivo studies performed on rabbits. The present technology could be a promising alternative to conventional drug delivery systems and traditional routes of administration for breakthrough pain management.
- Clonidine Maintenance Prolongs Opioid Abstinence and Decouples Stress From Craving in Daily Life: A Randomized Controlled Trial With Ecological Momentary Assessment. [JOURNAL ARTICLE]
- Am J Psychiatry 2015 Mar 17.:appiajp201414081014.
- AbstractPublisher Full Text
The authors tested whether clonidine blocks stress-induced seeking of heroin and cocaine. The study was also intended to confirm translational findings from a rat model of drug relapse by using ecological momentary assessment of patients' stress to test hypotheses about clonidine's behavioral mechanism of action.The authors conducted a randomized double-blind placebo-controlled clinical trial with 208 opioid-dependent patients at an outpatient buprenorphine clinic. The 118 participants (57%) who maintained abstinence during weeks 5-6 were continued on buprenorphine and randomly assigned to receive clonidine (N=61) or placebo (N=57) for 14 weeks. Urine was tested thrice weekly. Lapse was defined as any opioid-positive or missed urine test, and relapse as two or more consecutive lapses. Time to lapse and relapse were examined with Cox regressions; longest period of abstinence was examined with a t test, and ecological momentary assessment data were examined with generalized linear mixed models.In an intent-to-treat analysis, clonidine produced the longest duration (in consecutive days) of abstinence from opioids during the intervention phase (34.8 days [SD=3.7] compared with 25.5 days [SD=2.7]; Cohen's d=0.38). There was no group difference in time to relapse, but the clonidine group took longer to lapse (hazard ratio=0.67, 95% CI=0.45-1.00). Ecological momentary assessment showed that daily-life stress was partly decoupled from opioid craving in the clonidine group, supporting the authors' hypothesized mechanism for clonidine's benefits.Clonidine, a readily available medication, is useful in opioid dependence not just for reduction of withdrawal signs, but also as an adjunctive maintenance treatment that increases duration of abstinence. Even in the absence of physical withdrawal, it decouples stress from craving in everyday life.
- Cost Effectiveness of Injectable Extended Release Naltrexone Compared to Methadone Maintenance and Buprenorphine Maintenance Treatment for Opioid Dependence. [JOURNAL ARTICLE]
- Subst Abus 2015 Mar 16.:0.
- AbstractPublisher Full Text
The aim of this study was to estimate the cost-effectiveness of injectable extended release naltrexone (XR-NTX) compared to methadone maintenance and buprenorphine maintenance treatment (MMT and BMT respectively) for adult males enrolled in treatment for opioid dependence in the United States from the perspective of state-level addiction treatment payers.We used a Markov model with daily time cycles to estimate the incremental cost per opioid-free day in a simulated cohort of adult males ages 18-65 over a six-month period from the state health program perspective.XR-NTX is predicted to be more effective and more costly than methadone or buprenorphine in our target population, with an incremental cost per opioid-free day gained relative to the next-most effective treatment (MMT) of $72. The cost-effectiveness of XR-NTX relative to MMT was driven by its effectiveness in deterring opioid use while receiving treatment.XR-NTX is a cost-effective medication for treating opioid dependence if state addiction treatment payers are willing to pay at least $72 per opioid-free day.
- Buprenorphine use remains hit or miss. [Journal Article]
- Behav Healthc 2014 Nov-Dec; 34(6):24.
- Aggregator Full Text


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Analyst Research
|Report Title
KuybyshevAzot OAO: Business description, financial summary, 3yr and interim financials, key statistics/ratios and historical ratio analysis.
Provider: Reuters Investment Profile
Provider: Wright Reports
NYSE and AMEX quotes delayed by at least 20 minutes. NASDAQ delayed by at least 15 minutes. For a complete list of exchanges and delays, please click here.
KuybyshevAzot OAO Approves Industrial Gases Joint Venture with Linde AG's Unit-Interfax
Interfax reported that the Board of Directors at KuybyshevAzot OAO (KuibyshevAzot) has approved forming a 50/50 industrial gas production joint venture with Germany's Linde AG, the Russian company said in a statement. The new company will be established jointly with Commercium Immobilien und Beteiligungs GmbH, which is part of Linde AG. KuibyshevAzot will own 50% of the shares, par value RUB 1 million, which may in time be increased to RUB 1.5 billion. In other words, charter capital will initially be RUB 2 million with a view to being increased to RUB 3 billion. The Russian company was supposed to own 24% of the joint venture, with a nominal value not topping EUR 15 million at the Central Bank of Russia's (CBR) exchange rate. However, at a meeting on February 4, KuibyshevAzot's Board of Directors gave tentative approval to change the stake to 50%, with a nominal value of no more than EUR 31.5 million at the Central Bank's exchange rate. Last summer, KuibyshevAzot said that it had held talks with Linde AG to create a joint venture in the Samara region to produce industrial gases, followed by long-term supplies of hydrogen and ammonia to the Russian company. The project has been estimated to cost EUR 200 million, with plans to start implementing it this year. Tentatively, construction of the facility on KuibyshevAzot's basis is slated to finish up in 2016.
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In Winnieab's recipe for Lacto-fermented pickles are the two tablespoons of seasalt suppose to be coarse or fine? Thanks!
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Focused towards building long term relationships with clients and candidates, enabling us to be at the forefront in our specialist markets for a knowledge based human capital solution
We assist our clients by identifying human capital solutions to improve performance of teams, departments and organisations.
We are committed to understanding your career aspirations and will utilise our market knowledge and experience to identify the right career enhancing opportunities.
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You may have noticed things look a little different around here - we've switched to a new platform (XenForo) and have some new forum styles and features. This how-to guide will help you find your way around. If you find anything that looks strange, post it in this thread.
Acer Vs. Gateway
Discussion in 'What Notebook Should I Buy?' started by Raj, Aug 29, 2005.
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Greenlee 7211BB-2 Slug Buster Knockout Punch Set - 2" Conduit
Brand: Greenlee Model: 7211BB-2 Condition: New
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Earn 12 Westside Dollars for every 1 piece purchased.
Greenlee 7211BB-2 Slug Buster Round Knockout Punch Set for 2" is used for slug removal. The unique punch profile splits slugs making the job easier. Use with standard Greenlee dies, draw studs and battery-powered, hydraulic, ratchet or manual drivers. Greenlee holemaking tools are made for the trade and is the preferred brand of the electrical contractor.
Features:• Unique punch profile splits slugs allowing easy slug removal
• Use with battery-powered, hydraulic, ratchet or manual drivers
• Uses standard Greenlee dies and draw studs
Specifications:• Model Number: 7211BB-2
• Capacity: Mild steel up through 10 gauge (3.5 mm)
• Application: Punch mild steel, aluminum, fiberglass and plastic
• Hole Sizes: 2.42" Conduit Sizes: 2" Hole size is outside diameter of US conduit sizes; Example: 1/2" conduit size punch actually makes a 7/8" hole
• Pg Sizes: European standard pipe sizes
• ISO Sizes: International Standards Organization pipe sizes
• Operation: Battery, hydraulic, ratchet or manual drivers
• When used with ratchet, hydraulic or battery drivers, buy the punch and die only; the draw stud is part of the driver kit
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text:
March 28, 2015
NASHVILLE, Tenn. (AP) -- The U.S. Department of Agriculture reports Tennessee farms are smaller and fewer in number than they were several years ago.
There were 79,280 farms last year, down 9 percent from 2002, according to the U.S. Census of Agriculture. The amount of land in farms was just under 11 million acres, down 6 percent.
State Agriculture Commissioner Ken Givens attributes the fewer farms to less tobacco production in Tennessee since the end of federal price supports for the crop in 2005. The number of tobacco farmers in Tennessee fell by 80 percent between 2002 and 2007.
In many parts of the state, the pressures of urbanization also contributed to the change.
Nationwide, the number of farms increased 4 percent between 2002 and 2007. Tennessee was one of 11 states that saw the number of farms decline over the five-year period.
Information from: The Tennessean, www.tennessean.com
(Copyright 2009 by The Associated Press. All Rights Reserved.)
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Wadena woman faces felony assault charge
A Wadena woman faces a felony domestic assault charge after an altercation with her ex-boyfriend on March 9.
According to Wadena County District Court records, Sarah Ann Warner, 25, was charged March 12 with felony domestic assault, and an omnibus hearing has been set for March 31.
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text: Flat #0(zero) lensboard(96 x 99mm) with Linhof Cable Release Quicksocket(quick-release system) specific to a modern Compur #0 shutter, cone quick-socket adapter for your cable release. Fits Master Technika 45, Super Technika IV and V, Master Technika 2000 and Technikardan 23/45. NOTE: This board does not fit models Technika III and older.


text:
Activated CD4+ T cells enhance radiation effect through the cooperation of interferon-γ and TNF-α
1 Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama 36604-1405, USA
2 Research Laboratory of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, 22 Zhongguancun Nandajie, Haidian District, Beijing 100081, PR China
3 Yale University School of Medicine, Department of Internal Medicine, Hematology Section, 333 Cedar Street, P.O. Box 208021, New Haven, Connecticut 06520-8021, USA
BMC Cancer 2010, 10:60 doi:10.1186/1471-2407-10-60Published: 23 February 2010
Approaches that enhance radiation effect may lead to improved clinical outcome and decrease toxicity. Here we investigated whether activated CD4+ T cells (aCD4) can serve as an effective radiosensitizer.
CD4+ T cells were activated with anti-CD3 and anti-CD28 mAbs. Hela cells were presensitized with aCD4 or conditioned supernatant (aCD4S) or recombinant cytokines for 2 days, followed γ-irradiation. The treated cells were cultured for an additional 2 to 5 days for cell proliferation, cell cycle, and western blot assays. For confirmation, other cancer cell lines were also used.
Presensitization of tumor cells with aCD4 greatly increased tumor cell growth inhibition. Soluble factors secreted from activated CD4+ T cells were primarily responsible for the observed effect. IFN-γ seemed to play a major role. TNF-α, though inactive by itself, significantly augmented the radiosensitizing activity of IFN-γ. aCD4S, but not IFN-γ or IFN-γ/TNF-α combination, was found to enhance the γ-irradiation-induced G2/M phase arrest. Bax expression was highly upregulated in Hela cells presensitized with aCD4S followed by γ-irradiation. The radio-sensitizing activity of aCD4 is not uniquely observed with Hela cell line, but also seen with other cancer cell lines of various histology.
Our findings suggest possible molecular and cellular mechanisms that may help explain the radio-sensitization effect of activated lymphocytes, and may provide an improved strategy in the treatment of cancer with radiotherapy.


text:
In-depth analysis on Credit Writedowns Pro.
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Employees of Kistner Concrete were outside the County Courthouse this afternoon, using the sidewalk along the Tonawanda, for a team building exercise. The goal was to roll a ball through a series of half-tubes down the length of the sidewalk until it was successfully dropped in a basket. Each team member had to advance the ball and then move to the end of the line and wait for the ball to roll to their position again.
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logo for APlus (Australian Professional Lines Underwriting SpecialistsP
Paulr2 picked a winning design in their logo design contest. For just A$295 they received 143 designs from 65 designers.
Here's a peek at the client's brief
Graphic design made easy
99designs gives you quality graphic design at an affordable price. Just tell us what you need, get dozens of designs and choose your favorite.


text: We stayed for four nights at the Sofitel in a junior suite. It's in a great location on Copacabana beach, and the hotel supplies free chairs and towels and umbrellas on a small section of the beach for guests, which is great. The hotel feels a little dated, but nice just the same. The wifi is extremely spotty and slow,... More


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|Blog Posts
it's almost halfway through december 2010, and besides your having to rush around to attend christmas parties and buy last-minute christmas gifts, it's time to consider that big decision
where are you going to party on new year's eve?
do you see yourself spending the evening drinking way too much alcohol and making out with some random stranger? or do you see yourself spending the evening nibbling on healthy stuff and doing some downward-facing dogs with people you regularly see in yoga class?
yeah, i know the former sounds way more exciting, but seriously, the latter will score you more karma points in yogic heaven. or so i'd like to think, anyway...
so here are some yoga celebration suggestions i've found so far. you can party-hop all you want, just make sure you plan your stops so that you're where you want to be, with whom you want to be, when the clock strikes midnight on january 1st 2011!
LA Yoga Presents: A New Year's Eve Extravaganza Benefiting YOGA For Youth
Friday, Dec 31st 2:00pm - Saturday, Jan 1st 3:00am
4144 Glencoe Ave, Marina del Rey, CA
Cost: Pre-Sale tickets from Oct 26th - Dec 1st are only $35 ($50 at the door)
For advanced tickets go online now to: http://www.LAYogaNewYears.com
Pre-sale tickets also available for pick up Nov. 1st atEuphoria Loves Rawvolution - 2301 Main St, Santa Monica
Kathmandu Boutique - 1844 Lincoln Blvd, Santa Monica
Enjoy a celebration worth supporting, as LA Yoga Magazine hosts a special benefit event, raising capital & consciousness for the YOGA For Youth Foundation. Featuring Rocky Dawuni, Luminaries, Donna De Lory, The Makepeace Brothers, Seane Corn, Bryan Kest, DJ Fabian Alsultany, & Kia Miller.
This event begins Friday, December 31st at 2pm, with Yoga Instruction from some of LA's finest teachers, and rolls into live music at 7:30pm all the way till 3am in the morning!!!
Food vendors include raw & vegan cuisine by Euphoria Loves Rawvolution, & The Samosa House. Plus organic elixirs & drinks at the bar. There will be eco/green booths, and beautiful lounge space for all to enjoy!
Y.O.G.A. for Youth brings Yoga and Meditation to urban youth in schools, community facilities, detention centers and jails in order to enrich their lives and assist them in effectively meeting life's challenges. Please support this amazing cause, and enjoy the best New Year's Eve of your life!
The high-point of the event will be when all of us connect for an 11-minute midnight meditation. This will mean: 1100 people will get together for an 11-minute meditation at 11:49pm eleven minutes before we enter 2011.
Personal and Planetary Intention Setting for 2011 with Wahe Guru Kaur and friends
Friday, Dec 31st 5:00-8:00pm
Cost: $25 by 12/23, $40 thereafter
A joyfully cathartic spiritual experience that will leave you feeling deeply peaceful and whole.
Through the use of the Healing Breath and other shamanic healing techniques you will be taken on a journey of clearing, release and healing. You will move toward a space of clarity about your next right steps on your spiritual path. It will be an exploration into the profoundly authentic individual that you are, how you are a part of sacred community and how you make a difference on the planet.
Complete and release all that you have carried with you from 2010 and set your intentions to create a fresh slate for the New Year! As we approach the Aquarian Age we must gather together in ceremony and celebration – to remember who we are and why we came here!
Wahe Guru Kaur, Haridass Kaur and the Healer Training graduates will be there to support you in your transformative healing experience.
Please bring a cushion, blanket and any healing tools that you wish to use on your journey. Light snacks provided.
New Year's Eve Class with Guru Singh
Friday, Dec 31st 6:15-8:30pm, doors open at 5:00pm
Yoga West, Los Angeles
Cost: $30 - RSVP by December 30th
Light refreshments will be served prior to class.
Students must arrive by 5:45pm. After 6:15 no late arrivals will be seated.
New Years Celebration - Intentional Yoga and Bliss Bomb Rocking Kirtan!
Friday, Dec 31st 7:30pm-midnight
Rising Lotus Yoga, Sherman Oaks
Cost: Yoga Class only - $20 in adv/$25 at the door
Kirtan Only - $20 in adv/$25 at the door
Both Events - $30 in adv/ $35 at the door
• 7:30 - 9:30 pm
We will bid 2010 adieu with a bang of community practice lead by Claire to live music by Daniel and friends. We'll align ourselves as one in joyous flow and welcome 2011 in with grounding rituals that cultivate clarity for envisioning the path ahead, collectively and individually.
• 10:00 pm to Midnight
Join Daniel & Friends for a joyous, rocking, intentional New Years Eve Kirtan to celebrate the dawning of 2012. We'll sing and dance as we set our intentions and welcome the New Year. Chant and be happy!
• Midnight - ?
Potluck Feast and Champagne~! for those who wish to stay and celebrate, we'll gather upstairs to a feast. If you plan to attend the potluck there is no additional charge, only a dish to share with the group. Please let us know if you plan to attend and what you will be bringing!
Musical family for the eveningEmily Kerns, Shannon Baker, Arielle Silver, Jeff Harris, Darby Orr, Greg Klimuck, Cooper Madison
Sing and Dance into 2010!
For details and to RESERVE YOUR SPACE! (We expect a full house of love~!)
Yoga Mala (108 Sun Salutations) with Peter Barnett & Others
Friday, Dec 31st 8:00-10:00pm
Black Dog Yoga, Sherman Oaks
Cost: FREE!
Yoga Mala is traditionally practiced to observe something of great significance. At year's end we remember all that we are grateful for: our health, our families, our friends and our freedom. We mindfully observe the passing of the previous 365 days and welcome the beginning of the New Year.
Join us for champagne and hors d'oeuvres following the practice.
Students of ALL LEVELS of practice are welcome and invited to participate to any degree.
Reservations are suggested. Call 818.380.0331
New Year's Eve Class and Party
Friday, Dec 31st 9:00pm-? (9:00pm Class, 11:00PM Party)
Yogis Anonymous, Santa Monica
Ally Hamilton, Charlie Samos, and Kourtney Kaas tag team for a special NYE flow class followed by the most incrediblest party of 2011 at YA so far ;)
We are going all out for this one. DJ, live musical performances, health-conscious food & drink and a champagne toast at midnight. Flow into the new year, YA style! More details coming soon....
New Year's Eve Celebration 2011 with Gurmukh, Gurushabd, Tej & Harijiwan
Friday, Dec 31st 9:00pm
Golden Bridge Yoga, Hollywood
Cost: $60/adv or $68/day of
Whoosh! Out goes the physical, mental and emotional debris of 2010, giving space for new opportunities and relationships to be found in the highly charged energy field of 2011.
This is a very exciting and energized year affording us a renewed sense of spirit with which to sail the seas of life's grand adventure! On New Year's Eve, let us use the power of group consciousness to draw infinite sums of energy and prana into us.
Golden Bridge opens it's doors for all in celebration, prayer, and community on New Year's Eve night! It will be a night of individual reflection, ecstatic kirtan and dance, yoga, deep meditation, chanting, the gong, and great company.
The Nite Moon Cafe will serve warm delicious Indian Cuisine along with sweets and yogi tea chai.
A rare season of time now calls us forth. Eleven is the cosmic jet stream of Infinity, join us New Year's Eve to catch this magnificent wave of energy being beamed down upon planet Earth. Together we will harness the electrical flow of the Universe to purify and elevate our spirit in a new dimension of reality. Your angels are calling you home, it's all right here at Golden Bridge.
Join us on this magical evening as we link our prayers with all the seekers of light on the planet and blend the clear light of compassion into every aspect of our lives.
New Year's Yoga Celebration
Friday, Dec 31st 10:00pm-Midnight
Liberation Yoga, Los Angeles
Cost: $45
Ring In 2011 the RIGHT WAY! With Yoga! It's a tradition at Liberation~ includes lots of yoga, surprises and Champagne! This always sells out so get your seat now!
~~ and when the new year's eve parties are over, there's more new year celebrating to do!! ~~
A Bit of Heaven in 2011 with Bekah Finch ~ 2 Hour New Year Restorative ~
Saturday, Jan 1st 10:00am-12:00pm
Yoga Blend, Burbank
Cost: $25 by Dec 25th / $30 after
Are you tired of starting off the new year exhausted or hungover? Then let 2011 be the year of something new! Join Bekah for a 2 hour renewing restorative practice that will allow you to release the holidays, relax completely and create a sacred space to set your new year intentions in a balanced, peaceful way.
Space is limited so sign up soon!
NEW YEARS DAY CLASS AT THE HDC with Marc Holzman
Saturday, Jan 1st 10:30am-12:30pm
Guerilla Yoga at Hollywood Dance Center, 817 Highland Ave (at Waring), Hollywood
Cost: $15 Donation
Oh to be back in LA will be just divine! Please join me for a delicious, 2-hour, reunion practice to ring in 2011.
Please RSVP/ASAP to firstname.lastname@example.com so that I can reserve the appropriate size room.
111 Sun Salutations to Ring in the New Year!
Sunday, Jan 2nd 1:00-4:00pm
Brazilian Yoga and Pilates, Atwater Village
Cost: Suggested $10 donation
Please join us as to salute a healthy and prosperous 2011 with 111 sun salutations taught by ALL the BYP teachers in 15 minute increments. A delicious sampler platter of our amazing teachers, including new instructors to the BYP family!
Munchies, music and other fun activities await, along with class packages at discounted rates!
All Levels class starts at 1:00 pm.
Bring a mat & grab your spot early.
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Have you wanted to experience a polar plunge, but too afraid to jump in front of a crowd of people? Be a part of our first interactive video at sanduskyregister.com.
Here's how it works...
Sandusky County sheriff Kyle Overmyer and special prosecutor Dean Henry joined the "Between the Lines Live" program by telephone on Thursday (at about the 20-minute mark in this video) and offered some pretty interesting explanations for things that seem inexplicable.
Just prior to the destruction of Alderaan, the captured Princess Leia had this exchange with Imperial Governor Tarkin in 1977's Star Wars Episode IV: A New Hope:
Jim and Ashley moved into Ashley's father's home when he passed away years ago. Even though the mortgage was in Ashley's father's name, they continued to make payments to the bank, GMAP, for some time thereafter.
Online Contact Form419-625-5500800-466-1243314 West Market St.Sandusky, OH 44870


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Winnipeg Free Press - ONLINE EDITION
New research tracks 11,300 years of climate
Scientists have a good sense of what the Earth's climate has been like over the past handful of centuries. But what about many thousands of years back?
In a recent article in the journal Science, researchers at Oregon State University and Harvard explained how they used marine fossils to piece together a rough temperature record going back 11,300 years to the most recent ice age. That record indicates that the Earth warmed as it emerged from the ice age, followed by a long-term cooling trend. The cooling continued until the industrial revolution, when humans began burning fossil fuels in earnest — and pumping heat-trapping greenhouse gases such as carbon dioxide into the atmosphere. Then the temperature spiked. With the amount of carbon dioxide already in the atmosphere, models suggest, the Earth's average temperature in 2100 will surpass that detectable in any of the millennia studied.
The most dramatic implication of the study is not the magnitude of the current warming but its extremely rapid pace. The authors note that the Earth has warmed over the past century as much as it cooled over several millennia before that, with no similar spike detectable in the data. That finding would be yet more strong evidence against climate skeptics who cling to the wishful thinking that global warming is an entirely natural phenomenon.
The scientists have more to do. The recent warming has been so quick that it's still hard to tell whether there were any similarly brief and sharp temperature spikes many thousands of years ago that quickly abated. Michael Mann, a prominent climate scientist, suggested to the New York Times's Andrew Revkin that the temperature estimates match more robust records of recent temperatures so well that their conclusions should be taken seriously. They should also spur more research.
As scientists continue to refine their sense of how the climate behaved since the most recent ice age, Mr. Revkin points out that perhaps the biggest unknown that will affect the future of the climate is human behaviour. Debates will continue about exactly how sensitive the climate is to greenhouse emissions from the burning of coal, oil and natural gas. But the evidence does not allow policy-makers to ignore scenarios that predict very serious warming over the next century if world leaders — including policymakers in the United States — continue to do too little.
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Before I moved to St. Louis last year, my impressions of the city were based mainly on memories from a few family trips in my childhood, in which, of course, the famous Arch loomed larger than anything else. Well, except for the Christmas when it snowed 12 inches (!) — one of only two white Christmases I've experienced in my life.
Ever since then, I've associated St. Louis with wintertime in my mind. And now I'm living here — and it's winter! So what does an honest-to-goodness St. Louisan do for fun in "the Lou" when the weather turns cold (if not necessarily snowy)?


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Wednesday, May 05, 2010
8 comments
Friday, April 30, 2010
5 comments
I am happy to report Mr Vertigo has gone, energy levels are back up! Woo hooo!
Heading off to the fancy dress shop to get a disco outfit for my daughter Jen.
Have a great day everyone
ps A big thank you t... Read more
Friday, April 30, 2010
11 comments
I have this visitor called vertigo! And it decided to visit this morning ! NOT HAPPY JAN!
Managed to drive to the airport to pick up Jen, my daughter. It was so lovely to give her a big hug!
So with Jen jet lagged and me with my vis... Read more
Thursday, April 29, 2010
8 comments
I go to the airport to meet my daughter tomorrow! Can't believe it is finally happening!
Been busy at my sister's washing,cleaning,cooking and loving it. I keep telling myself that I am helping make memory's.
I reflect back to things t... Read more
Tuesday, April 27, 2010
6 comments
Hello all,
It is cold,wet,and windy.
So I am still in bed with laptop on my lap!
Trying to give my immune system some help as sinus headache getting slowly worse!
Will get up soon and go visit my mum.
Havn't been exerc... Read more
Monday, April 26, 2010
4 comments
Well count down is getting close! Can't believe it is already Tuesday! Most of the extended family arriving on Friday, including my darling daughter. Have not seen her for 4 months! Organising a trip around Tasmania to catch up with other family... Read more
Sunday, April 25, 2010
7 comments
I needed that as I have just finished food tracking for the last 24 hours and am 500 calories over!!! the first time since starting Sp in Feb 2010.
At least I am being honest with myself!
So lots of exercise tomorrow and less calor... Read more
Wednesday, April 21, 2010
3 comments
Tuesday, April 20, 2010
4 comments
Went to my sister's house as youngest niece has not been well. She went to school as felt well enough to do so, so I was the on call Aunt in case the teacher's called to say she needed to come home.
No call, she is a tough little cookie!
... Read more
Monday, April 19, 2010
6 comments
Boy, what a fun filled weekend that was!
On both days managed to fit in a short walk/run and on Sunday a 5km walk on the treadmill. Rest day today, might just do a slow walk along the beach.
Am minding my 8 year old niece today as she... Read more
Saturday, April 17, 2010
6 comments
Was so pleased to have been here for my dad's 81st birthday.
Due to timing of other commitments ie a school reunion in Tasmania then a nephews wedding in Queensland, ... Read more
Thursday, April 15, 2010
6 comments
Full on day today. Caught up with my brother who had to fly interstate to get to Tasmania. As he is unable to make it for my sister's 40th on the 1st of May, he is able to be here for my dad's 81'st on Sat the 17th of this month.
Managed ... Read more
Wednesday, April 14, 2010
6 comments
Am currently staying with friends and had a high fat dinner last night, food like smoked trout pate, smoked cheddar cheese, olives, ham, cold roast veggies.
So today was lots of walking and healthy eating, was able to keep to my calorie l... Read more
Tuesday, April 13, 2010
1 comments
Just a quick hello.
Making the most of this glorious weather , have been for the hill walk and some more! Getting over the Jet lag and cold is more of a sinus thing. Adjusting to cooler weather.
Just about to head off to see mum. Each ... Read more
Monday, April 12, 2010
5 comments
Enjoying a lazy morning. Have a headache, maybe getting a cold! Usually a hot shower fixes it. Am off to have lunch with my dad and step mum, so need to get out of bed and get moving.
Managed a great hill walk with my sister yesterday and o... Read more


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Welcome to PG Designs
Welcome to PG Designs, your home based web design, graphic design and social media specialist. Based in Prince George we have been in operation since 2003. I have experience with industries from the Automotive to waste disposal and everything in between and know I can help you take your business to the next level.
My name is Trish Clark, I have lived in Prince George all my life and so proudly call it home. I have seen the building of Pine Center, the creation of UNBC and eagerly awaited the coming 2015 Canada Winter Games. I also have a huge interest in all animals but specifically dogs, having 2 rescue dogs myself and devote a lot of time to helping various rescue groups from San Diego to Quebec.


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Homemade Vitamin C Serum
162 reviews
89% would repurchase
Package Quality: 3.8
Price: $$
Package Quality: 3.8
Price: $$
on 10/4/2014 6:22:00 PM
Age: 25-29
Skin: Very Oily, Medium, Warm
Hair: Brunette, Wavy, Medium
Eyes: Brown
I decided to try the DIY route with this because the research I found stated that vitamin C degrades quickly once mixed with distilled water and exposed to oxygen-eventually making it useless for your skin-and a total waste of money for whatever product you paid for claiming it has vitamin C in it. I bought the L-ascorbic powder for a reasonable price on Amazon. I use an old small spray bottle to mix and store in. The recommended constitution for 20% vitamin C is 4 tsp distilled water to 1 tsp powder. I make a new batch every seven days or so, I apply this every night with hyaluronic acid, coconut water toner, and my mixture of vitamins A and E.
It burns/tingles for a few seconds after application-especially if I just exfoliated but it isn't anything too terrible. For god sakes don't get this in your eyes though!
My skin has seemed to improve since using this but I use an arsenal of products so it is hard to say if this alone helped.
I will keep using this because it is 100% organic, cheap, and my skin seems to benefit from it.
Make sure you mix it well it takes a few minutes of swirling after mixing to disintegrate into the water.
on 8/29/2014 12:02:00 AM
Age: 30-35
Skin: Very Oily, Medium, Neutral
Hair: Brunette, Straight, Fine
Eyes: Brown
I really love what vitamin c does for my skin. It really helps to even the tone and texture of my skin. I see a reduction in blemishes as well. I just do not like having to mix up a new batch all the time. Needless to say I have fell off the band wagon. I do catch a ride from time to time but I like my routine to be quick so I do not make this that often which is a shame and I really should just suck it up but I haven't so far hopefully one day lol.
That being said I do reallllly Love this. I do not like glycerin though as it causes me to break out no matter how little I use so I tend to leave it out of my recipe.
I found the best formula for my skin is just vit c and water. You can also put it in a dark colored travel spray bottle and spritz on like a toner.
on 7/31/2014 9:52:00 AM
Age: 25-29
Skin: Dry, Fair-Medium, Not Sure
Hair: Brunette, Other, Other
Eyes: Brown
I love this! I Have tried everything for my dry sensitive comendoegenic prone skin. Cetaphil, proactive, neotrogena, clearasil, clinique, este lauder, clarins i even went to all natural cocnut oil avcado oil....this list can go on and on. Basicly I've tried just about everything hoping it would work. Doing minimal research an trying anything. One day i saw a couple youTube videos that didn't give me the answer but gave me the answer. One pointed out that i have been basicly shotting in the dark hoping and praying i hit something by doing minimal research about my skin. The other one gave me good research places to find the information i was seeking for my specific skin type.Realizing eveybodys skin is uniquely different like a fingerprint. My skin, like everyone else has the same basics and then there are the indepth up close differences i had to learn about to treat/ help myself.One of the things i learned was vitamin c serum was something i wanted to try because of my acne and all the scaring. I started with NuFountain vitamin c 20% i loved it! it made my skin glow reduced my scaring my forehead wrinkles and it actually helped get rid of my acne in less then 8 weeks.i did it 2x a day and at 22 a bottle i cant really say no. Until I found out how easy and much cheaper it would be to make my own and even make some for a few friends to try. So i got it off amazon for $11 LAA. I found a few recipes read the ingredients in the NuFountain bottle and followed. I LOVE THIS! and so do my friends. i highly recommend trying this. I am defenitly more inclined to making my own stuff especially since i havent tried to get acne meds or washes and i have been saving sooo much money.
on 7/30/2014 11:39:00 PM
Age: 30-35
Skin: Sensitive, Fair, Neutral
Hair: Brown, Straight, Fine
Eyes: Brown
I make a very basic serum, 1/4t of fine powdered LAA, with 1 and 1/4t distilled water, swirl it around in a small glass beaker and transfer it to an brown glass dropper bottle. Each batch lasts a few days which is perfect since it does not stay stable/active for long. Since it's just water and LAA the formula is runny. My skin looks great, my forehead lines are much smoother and my 11 is diminished as well. The first few applications burned a bit as I was not used to 20%, but my face quickly grew accustomed to it. DIY C serum is such a huge bargain. I paid right around $10 total for a jar of LAA, a Gallon jug of distilled water, and a brown glass dropper bottle. It's going to take months for me to use the jar of LAA and I purchased the smallest size available. I love not paying $50 for a bottle of serum when I can make my own for pennies.
on 7/25/2014 6:34:00 PM
Age: 30-35
Skin: Sensitive, Olive, Neutral
Hair: Brunette, Wavy, Medium
Eyes: Brown
I'd say this is my HG skin product, and it's really cheap to make. If I run out and don't get around to mixing up more for several days (...or weeks...), I WILL notice a difference--in the form of blackheads AND cystic acne! Ugh and OUCH. I think this is because the vitamin C's antioxidant properties keep the sebum in my pores from oxidizing and that its anti-imflammatory goodness keeps the deep cyst-forming processes from growing those giant, painful lumps.
And speaking of cystic acne, I've had a lot of it, and my face has borne the scars. Using a vitamin C serum morning and night has faded those scars significantly, and my version uses humectants to provide some kick-ass hydration as well. When it's humid enough out, I don't even need to use an additional moisturizer.
I've played around with percentages and hit on the exact formulation my skin loves best:
74.5% distilled water (22.35 g)
15% L-ascorbic acid (4.5 g)
10 % glycerin (3 g)
0.5% hyaluronic acid (.15 g)
I make it in 30-gram batches, because that amount fits perfectly into 1-oz amber glass dropper bottles and I can use it up in about 3 weeks to a month, so it doesn't oxidize and turn orange before I can use it up (provided I refrigerate it).
I know some people like to use vitamin C powder as they go, adding it to their morning moisturizer or other serum or something, but my sensitive skin and my engineer's brain prefer a more constant amount of vitamin C-- times when I've tried to mix it up on the fly haven't turned out well. It's far too easy to use too much vitamin C powder for a single use, which can be irritating to my skin and is also is a waste of my precious ingredients. I have to do all kinds of math and science to keep my skin happy. :)
I find that the vitamin C dissolves best if I don't just use crystals. I grind it up with mortar and pestle to get a finer consistency, but in the future I might just buy an ultra-fine powder to start with, even though it'll cost more.
Back when I first started making the serum, I didn't have the hyaluronic acid yet, and my recipe used equal amounts (by volume) of water and glycerin. That worked fine, but it was SO STICKY! I still like glycerin (it's really good for your skin!) but adding the HA makes this more potent in the hydration department and also helps to thicken the formula up, which I prefer. BTW the HA I use comes as powder, but you could also use a pre-made 1% HA serum here. That half-percent is the highest amount of HA powder I've been able to fully dissolve when other ingredients are included.
The dropper bottle I use does allow air into the serum when I use it, so it's not perfect. Ideally I'd have either an opaque glass airless pump bottle for this, or a broad-spectrum preservative (that could do well at such a low pH) but I haven't had any trouble with anything growing in it and subsequently on my skin (knock on wood).
on 7/20/2014 6:40:00 PM
Age: 19-24
Skin: Combination, Fair, Not Sure
Hair: Black, Straight, Medium
Eyes: Brown
So I've been applying my homemade Vitamin C toner along with Cerave Facial Moisturizing Lotion PM for about 3-4 weeks now. After reading a bunch of benefits deriving from vitaminc C and niacinamide, I decided to give it a try. This time around, I've managed to use my old vitamin C pump bottle and put the mixed solution in there instead of of some random lid and spread it on my face daily, which btw is a bitch to do. I use about 1/4 tsp of ascorbic power and 1 tsp of plain old tap water, sometimes a bit more or less. This mades a roughly 20% vitamin C solution. People say to use distilled water but I keep forgetting about getting it from the store. I've put in an empty toilet paper roll to give it extra light protection and put it in the fridge since it's summer now and the heat can ruin the solution quicker. I find making this much amount of vitamin C toner is perfect because it typically lasts me about 4-5 days and vitamin C loses its efficacy quickly anyway. Also, when I apply the vitamin C with it being well-mixed, the doesn't leave my skin feeling dry and grainy like before.
I don't know if it's vitamin C itself, the Cerave lotion, or both but ever since I've been applying vitamin C serum in the morning along with applying Cerave lotion at night, I've been noticing my skin getting smoother and freckles less noticeable. My face's been feeling slightly fuller as well. Even the redness around my nose is getting a lot less noticable. My skin's been looking brighter and reflecting light better, and not because it's oily. And my skin doesn't break out from this, which is definitely a plus.
I haven't worn makeup in a while and my boyfriend told me I look great waking up in the morning. And I do notice my skin looking better without makeup as well. And just last week, some guy hit on me, even though I wasn't wearing any makeup and had horrible messy hair. I imagine the new skin routine has something to do with it.
on 7/6/2014 9:05:00 PM
Age: 18 & Under
Skin: Dry, Medium Brown, Not Sure
Hair: Brown, Other, Other
Eyes: Brown
lightened my skin, got rid of my breakouts from. I have a nice glow, only use it at night.
I replaced glycerin with grapeseed oil. Use this link get me credits and get yourself $4 on 450g of vitamin c powder. Note that all forms of ascorbic acid are the same, just because there's no L does it diminish it's vitamin c powder.
on 6/29/2014 11:33:00 PM
Age: 44-55
Skin: Combination, Fair, Neutral
Hair: Brown, Straight, Fine
Eyes: Blue
PROS: Lightens skin, helps with pores and even wrinkles a bit. SO inexpensive.
CONS: Can irritate if the percentage is too high for you (I start at 5% and work upward.)
ALTERNATES: NuFountain has one with ferulic acid which is nice but much more expensive.
on 6/21/2014 11:09:00 PM
Age: 36-43
Skin: Oily, Fair-Medium, Neutral
Hair: Brunette, Wavy, Coarse
Eyes: Brown
I started making this because every commercial Vit C product that I tried was so expensive and too moisturizing. I just mix a generous pinch of the L-ascorbic acid (bought thru Amazon.com) with 99% pure aloe vera gel (Vitamin World brand purchased thru Puritans Pride) in my cupped hand until it dissolves and use a dollar store makeup brush to apply. I use mild soap to wash my hands and the brush afterwards b/c it can stain. This is cheap, natural, fresh and very effective for my face! It tightens my pores, dries up zits, lightens dark marks, heals any popped zits (I know, don't judge me) and tames my oiliness. It's strong, so I only use it 2 or 3 times a week before bed. It really Increases my photosensitivity, so daily sunscreen is a must.
on 6/16/2014 10:15:00 AM
Age: 25-29
Skin: Combination, Tan, Not Sure
Hair: Brown, Other, Other
Eyes: Black
Dear Ladies, thank you for reviewing so many items here on MakeupAlley..you cant imagine the experience I had just going over what you all had tried bc I only recently begin a skincare regimen amd I wanted to buy good stuff, but it was really confusing. I don't want to try every product out there ..I was going to get caught in the hype of many ads. but reading your reviews made me think for a while.Luckily, I found out about PAULA's Choice reviews and I was STUNNED..most of the advertised creams are pure RUBBISH..I even related reviews of products in her site with reviews of the same products here in Makeup Alley..God they results are so similar like if a product is rated average in PC then 50% of people here would recommend and if it is poor in PC then maybe less than 30% would buy the product again( beautipedia reviews--> brand reiews)
I know some of you do know about PC reviews but for other ladies ..I highly recommend u read ALL REVIEWS
I decided to try and make my own Vit.C serum before I read your reviews I was going to buy Skin Cuetical AOX vit.C but I thought I would try this first..ONE thing : Ladies who are making their VIT.C serum NEVER EVER use vodka or any alcoholic beverage for your skincare recipes, NO FRAGNANCE OILS: rosewater, lavender IT IS EXTREMELY HARMFULL AND IRRITATING FOR YOUR SKIN( read Paula's Choice reviews on alcohol and fragnance in skincare products)
I would try to use vitamin c capsules with rosehip and tell you about it next time...
Popular Treatments (Face)