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Blake Griffin
Clippers embarrass Sixers, coast to 45-point win
Feb 10, 2014, 12:44 AM EDT
The Los Angeles Clippers won by 45 and it wasn't that close. Seriously. Sunday night was just a perfect storm of everything going right for the Clippers and everything going wrong for the Sixers. This was a game where the Clippers were ahead 100-51 after three quarters and went on to win 123-78. Here are…
Blake Griffin on the Dunk Contest: 'It's something I would never do again'
Feb 9, 2014, 8:00 AM EDT
Blake Griffin won the 2011 Dunk Contest by doing something that had never been done previously, and won't be duplicated again. The man jumped over a car. While we can debate whether or not that sounds a lot more impressive than it actually was, the vibe at Staples Center was electric when the car was…
LeBron says he should be Defensive Player of the Year
Feb 7, 2014, 12:55 PM EDT
It's going to be Roy Hibbert. If you were going to bet on one sure thing out of the NBA's awards this season, you should bet on Roy Hibbert being named Defensive Player of the Year. More than Durant as MVP or Michael Carter-Williams as Rookie of the Year, Hibbert is a lock for DPOY.…
Mario Chalmers fined $5,000 for flop against Blake Griffin (VIDEO)
Feb 6, 2014, 6:59 PM EDT
That play from Wednesday night worked for Mario Chalmers — he drew and offensive foul on Blake Griffin. He also flopped — and that's the second time this season he's been caught flopping so the league came down on him with a $5,000 fine this season. Yes, a whopping $5,000. To be clear, do the…
Giannis Antetokounmpo to compete in Skills Challenge during NBA All-Star Weekend
Feb 6, 2014, 6:14 PM EDT
Typically, rookies don't get noticed. Typically, players from overseas need more time to build an American following. Typically, Milwaukee Bucks are ignored. Giannis Antetokounmpo is definitely atypical. "The Greek Freak" has wowed fans all season with his long arms, diverse skillset and outward happiness. He's been so impressive, he'll be competing in Skills Challenge –…
Heat, Clippers had "Dunkfest 2014″ Wednesday night (VIDEO)
Feb 6, 2014, 3:59 PM EDT
Blake Griffin, DeAndre Jordan and the Clippers can put on show. LeBron James and the Miami Heat can throw it down with the best of them. When the two teams got together at Staples Center Wednesday night it was "Dunkfest 2014." It was an amazing show of athleticism. The Miami Heat raced out early and…
Clippers should get Chris Paul back on court Sunday
Feb 6, 2014, 8:44 AM EDT
The Clippers have gone 11-6 since Chris Paul went out Jan. 3 with a separated shoulder. It's been an impressive run, with Blake Griffin stepping up and showing off a more well-rounded game. In those 17 games the Clippers have averaged 111.7 points per 100 possessions, best in the NBA. It makes you wonder how…
The Extra Pass: Blake Griffin's alternate reality; plus Wednesday's recaps
Feb 6, 2014, 8:00 AM EDT
Tell me if this sounds at all familiar. 24 years old, about 6-foot-8, 6-foot-9. Roughly 250 pounds. Stronger and faster than just about everyone. Phenomenal basketball IQ. Highly skilled, but often criticized for what he can't do instead of appreciated for what he does. That's Blake Griffin. And at one point, that was LeBron James,…
Wednesday night NBA grades: Dwight Howard looks like guy Rockets thought they signed
Feb 6, 2014, 3:58 AM EDT
Our quick look around the NBA, or what you missed while wondering why anyone would live in a dumpster for a year, voluntarily… Dwight Howard, Houston Rockets. The NBA game is in large part about exploiting mismatches. With all due respect to the solid season Miles Plumlee is having, him trying to cover Dwight Howard…
Heat start hot then hang on to beat Clippers
Feb 6, 2014, 3:13 AM EDT
This was a nationally televised against a top-four team in the West in the Clippers — these are the kind of games that shake the Heat out of their mid-season malaise. And when the Heat play like they did early Wednesday night it is a beautiful thing. Miami's first quarter was as good as they…
Wednesday And-1 Links: "The Justice League Goes Inside the NBA: All Star Edition" comic book exists
Feb 5, 2014, 7:23 PM EDT
Here is our regular look around the NBA — links to stories worth reading and notes to check out (stuff that did not get its own post here at PBT) — done in bullet point form. Because bloggers love bullet points. • I LOVE that this exists. DC Comics has teamed with TNT's "Inside the…
The Extra Pass: Talking Blazers, Clippers, coaching with Bill and Luke Walton
Feb 5, 2014, 8:00 AM EDT
Portland Trail Blazers fans are not fair weathered. They have stuck with the franchise through some dark times. Now they are being rewarded — with LaMarcus Aldridge and Damian Lillard leading the way, Portland fans are getting to witness some of the best, most entertaining basketball Rip City has seen in more than a decade.…
The Extra Pass: Central heat, plus Monday's recaps
Feb 4, 2014, 8:00 AM EDT
No NBA head coach has been fired yet this season. Of course, "yet" is the key word there. Given the performances and the high expectations of a few teams in the Eastern Conference's Central Division, that could be changing soon. Here's a look at the tenuous positions of three coaches from that division, in order…
Denver's Randy Foye hits ridiculous leaning game-winning three (VIDEO)
Feb 4, 2014, 2:28 AM EDT
Just seconds before the Clippers' Matt Barnes had drained a three off a pass and a nice bit of improvisation from J.J. Redick. The Clippers had a two-point lead and looked like they were going to escape Mile High with a win. Then Randy Foye happened. Whatever Nuggets coach Brian Shaw drew up in the…
Monday night NBA grades: Tony Parker can still carve up a defense
Feb 4, 2014, 2:16 AM EDT
Our quick look around the NBA, or what you missed while realizing yes, the TSA employees are laughing at your body scans…. Tony Parker, San Antonio Spurs. The Pelicans are without Jason Smith for the rest of the season and that means New Orleans usually had Greg Stiemsma or Alexi Ajinca on the court —…
PBT NBA Power Rankings: Adam Silver signs the balls, Kevin Durant keeps shooting them
Feb 3, 2014, 2:21 PM EDT
A look at PBT's power rankings show basically the only thing that really changed this week was the signature on the Spaulding balls — Adam Silver's signature is in play. Aside that Durant has the Thunder on top and the Lakers continue fall like the lead balloon they are. 1. Thunder (38-11, Last Week No.…
Report: Clippers to sign Sasha Vujacic to 10-day contract
Feb 2, 2014, 5:00 PM EDT
The Clippers have continually been on the lookout for upgrades to the roster this season, in hopes of winning now with All-Star talent like Chris Paul and Blake Griffin already in place. L.A. tried its luck with Stephen Jackson earlier in the year before releasing him, and brought in Hedo Turkoglu for bench support as…
Jordan Brand celebrates grand opening of first Flight 23 store (PHOTOS)
Feb 2, 2014, 9:30 AM EDT
Jordan Brand has always had a huge retail footprint (pun intended), but had yet to open specialized individual retail stores of its own — at least until now. From the official release: "[Saturday] morning in midtown Manhattan, Jordan Brand president Larry Miller, Footaction CEO Jake Jacobs and filmmaker Spike Lee officially welcomed the first consumers to…
The Extra Pass: Which non-All-Stars will make an All-NBA team?
Jan 31, 2014, 8:00 AM EDT
All-Star selections have become the de facto measure of good seasons, even though they're really only the measure of good half seasons and rely on a gerrymandered system that splits players by conference. But All-NBA teams – which evaluate a full year and aren't split by conference – are a better metric for good seasons. In the last…
Report: Chris Paul targeting Feb. 7-9 return
Jan 31, 2014, 12:10 AM EDT
The Clippers have been impressive with Chris Paul out, having gone 10-3 in this stretch (heading into Thursday's game at Golden State). Blake Griffin has stepped up and his mid-range jumper has become a real weapon, Darren Collison has been solid at the point and the Clipper offense has been the best in the NBA…
Doc Rivers lobbied other coaches to vote DeAndre Jordan an All-Star. It won't be enough.
Jan 30, 2014, 2:26 PM EDT
Later on Thursday the NBA All-Star Game reserves will be announced — and in the Western Conference frontcourt a couple deserving guys will get snubbed. The fans voted in Kevin Durant, Blake Griffin and Kevin Love as the starters. There likely will be four (maybe five) front court replacement players from a group including LaMarcus…
PBT Extra: PBT does its own Rising Stars Challenge draft; plus Wednesday's recaps
Jan 30, 2014, 8:00 AM EDT
The NBA announced the field for the Rising Stars Challenge, but the teams won't be selected until next week. A sucker for any opportunity to hold a mock draft, I enlisted Kurt into holding our own. We followed the same positional rules whoever picks the teams on TNT next Thursday – the general managers have yet to…
Chris Paul working out with Clippers, no return date set
Jan 28, 2014, 11:41 AM EDT
What the Clippers have done without Chris Paul has been impressive — on the season the Clippers are 10-3 without him and they just went 5-2 on their Grammy road trip all with him sidelined. Blake Griffin has stepped up his game — in his last 10 games he is averaging 26.4 points a game…
The Extra Pass: Three guys that deserve more playing time, plus Monday's recaps
Jan 28, 2014, 8:00 AM EDT
With the first half of the season in the books, let's look at five players who deserve to get a little more burn the rest of the way. John Henson, F/C, Milwaukee Bucks Before we get to Henson, let's travel in the way back machine to the 2009-10 season. If you'll remember, Kurt Rambis was…
LaMarcus Aldridge thinks he should have been an All-Star starter
Jan 24, 2014, 2:53 PM EDT
If the NBA coaches and players were voting for who got to be an All-Star Game starter, LaMarcus Aldridge would be a lock in the West. But the fans wanted to see other guys (Kevin Durant, Blake Griffin and Kevin Love is your West starting frontcourt) so Aldridge will again be selected by the coaches…
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VIEWS: 13 PAGES: 1 CATEGORY: Internet / Online POSTED ON: 5/15/2012
READ FREE MANGA ONLINE http://mangachrome.com Those who have loved the art and stories but not got enough of it to enjoy, can rejoice now. Manga Chrome is providing manga online on mangachrome.com. The site is being promoted by a mini community sharing same interests. This provides for a common place for all manga-fans to share their artefacts with others online and win applause. Mangachrome.com presents an unending list of latest manga to enhance your excitement. Naruto latest series, Bleach, Claymore, History's Strongest Disciple Kenichi, Fairy Tail, Katekyo Hitman Reborn!, Mahou Sensei Negima, Skip Beat, and many more. More importantly, you can access all manga files for FREE here. They do not charge anything for reading manga online. The server is being managed privately by a small manga lover community and lacks all the modern sophistications this time. There may be time when you will find it shut down or too busy to access, or even offline so the best way is to try another time. As the server is pretty slow, the readers will need to download the files then open and run them. They clearly have denied any donation or charity offerings but do suggest you to extend it to manga scanlation groups as the most of the works published here have been taken from them only. The site accepts online paid advertisements, though. Those who have got their own manga and want to share it with the online manga community are encouraged to upload their stuff free here. Almost all the available manga comics are OEL manga (original English-language manga) There is a huge stock of manga comics for all age and gender of readers. This perhaps is the largest online collection of manga works. The site is quite easy to explore and still easier to use for uploading and downloading purpose. There is no gimmick or hype involved. They have clearly expressed their interest in running this site and their limitations, which further ascertains it to be a real manga fans site and not a commercial avenue meant for earning revenue. So, if you want to indulge in a new manga feature now, look no further, visit mangachrome.com and enjoy reading manga online. For more information about mangachrome, please visit http://mangachrome.com
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Open Economies Review
Open Economies Review features theoretical and empirical studies examining international economic issues or national economic issues with transnational relevance. In addition, it explores specific events emanating from important branches of the literature.
This journal provides a forum for all viewpoints and schools of thought, encouraging interdisciplinary communication and interaction among researchers in the field. Among the topics addressed in the journal are models and applications of trade flows, commercial policy, adjustment mechanisms to external imbalances, exchange rate movements, alternative monetary regimes, real and financial integration, monetary union, economic development, and external debt.
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Lovely! My Thunbergia has bloomed all year long - love this vine. I just pulled out a boat-load of walking Iris - they spread like wildfire, but sure are pretty!
M, beautiful spring colors!
All the iris' along my walkway are happy. I'm wondering if that means by summer they will be done? LOL.


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A process for producing crystalline form I of cabergoline, which process comprises crystallization of the desired form from a toluene/diethyl ether mixture comprising raw cabergoline, followed by recovery and drying of the resulting crystals. A new solvate form V of cabergoline, useful as an intermediate, is also provided.
1. A process for producing cabergoline Form I, which process comprises crystallisation of the desired crystalline form from a toluene/diethyl ether mixture comprising raw cabergoline, followed by recovery and drying of the resulting crystals.
2. A process according to
3. A process according to
4. A process according to
5. A process according to
6. Solvate form V of cabergoline having the XRD powder pattern of FIG. 5.
7. A process for producing solvate form V of cabergoline as defined in
8. A process according to
9. A process according to
10. A process according to
11. A process according to
This application is 371 of PCT/EP01/03099 filed Mar. 19, 2001, now WO 01/70740
The present invention concerns a new process for preparing crystalline Form I of cabergoline.
Cabergoline is an ergoline derivative interacting with D2 dopamine receptors and is endowed with different useful pharmaceutical activities and it is used in the treatment of hyperprolactinemia, central nervous system disorders (CNS) and other related diseases.
Cabergoline is the generic name of 1((6-allylergolin-8beta-yl)-carbonyl)-1-(3-dimethylaminopropyl)-3-ethylurea, described and claimed in U.S. Pat No. 4,526,892. The synthesis of cabergoline molecule is reported also in Eur. J. Med. Chem., 24,421, (1989) and in GB-2,103,603-B. Crystalline cabergoline Form I, an anhydrous not solvated form of cabergoline, was prepared by crystallization from diethyl ether, as described in Il Farmaco, 50 (3), 175-178 (1995).
Cabergoline Form I, like cabergoline, displays a significant inhibitory effect with regard prolactine and has therapeutic properties that make it possible to treat patients who have pathological conditions associated with an abnormal prolactin level, thus is useful in human and/or veterinary medicine. Cabergoline is also active, alone or in combination, in the treatment of reversible obstructive airways diseases, for controlling intraocular pressure and for the treament of glaucoma. It is also employed in the veterinary field, as antiprolactin agent and in cutting down drastically the proliferation of vertebrate animals. The several uses of cabergoline are for example described in WO9948484, WO9936095, U.S. Pat No. 5705510, WO9505176, EP040,325.
Cabergoline Form I is particularly useful in the treatment of Parkinson's disease (PD), Restless Legs Syndrome (RLS), treatment of diseases like Progressive Supranuclear Palsy (PSP) and Multysystemic atrophy (MSA).
During our development work we discovered a new process for preparing crystalline Form I.
Thus, the present invention concerns a new process for preparing Form I of cabergoline and a new solvate Form V of cabergoline useful as intermediate.
FIG. 1. XRD powder pattern of cabergoline Form I.
FIG. 2. DSC curve of cabergoline Form I.
FIG. 3. IR spectrum of cabergoline Form I (sample prepared by KBr powder technique).
FIG. 4. Solid state 13C-NMR spectrum of cabergoline form I.
FIG. 5. XRD powder pattern of cabergoline solvate Form V.
FIG. 6. DSC curve of cabergoline solvate Form V.
FIG. 7. IR spectrum of cabergoline solvate Form V (sample prepared by KBr powder technique).
FIG. 8. Solid state 13C-NMR spectrum of cabergoline solvate Form V.
Form I can be readily prepared according to the present invention starting from crude material by crystallization from a toluene/diethyl ether mixture, through a new solvate form V of cabergoline. The present process for preparing Form I shows advantages with respect to the old one because of its greater reproducibility.
X-ray powder diffraction (XRD), differential scanning calorimetry (DSC), infrared (IR) spectroscopy and solid state 13C-NMR were used to characterise the new form.
X-Ray Powder Diffraction
Powder X-ray diffraction was performed using either a Scintag X1 or X2 Advanced Diffraction System operating under Scintag DMS/NT© Ver 1.30a and 1.36b respectively, and Microsoft Windows NT 4.0™ software. The system used a copper X-ray source maintained at 45 kV and 40 mA to provide CuKα emission of 1.5406 Angstroms and a solid state peltier cooled detector. Beam aperture was controlled using tube divergence and anti-scatter slits of 2 and 4 mm and detector anti-scatter and receiving slits of 0.5 and 0.3 mm width. Data were collected from 2° to 30° two-theta using a step scan of 0.03°/point with a one second/point counting time. The samples were hand ground using a pestle and mortar and packed into an aluminum sample tray with a 12 mm (diam.)×0.5 mm cavity.
Measurements of differential scanning calorimetry were obtained on a Mettler TA 4000 thermal analysis system. Approximately 8.5 mg samples were accurately weighed into a DSC pan. The pans were hermetically sealed and a pinhole was punched into the pan lid. The use of the pinhole allows for pressure release, but still assures that the thermal reactions proceed under controlled conditions. The samples were introduced into the DSC oven and then heated at a rate of 5° C./min, up to a final temperature of 135° C.
IR Spectroscopy
IR spectra of cabergoline form I and V were obtained on a Perkin Elmer FT-IR spectrophotometer PARAGON 1000. The sample were prepared by KBr powder technique registering the spectra on reflectance.
Solid state 13C-NMR
Solid state 13C-NMR spectra were obtained on a MSL 300 Bruker instrument equipped with solid state facilities and variable temperature magic angle spinning probe. Cross polarisation experiments were performed by a decoupling field of 50 KHz and single pulse magic angle spinning experiments with recycle times ranging from 10 to 100 records. The x-ray powder diffraction pattern for Form I (FIG. 1) shows a crystalline structure with useful distinctive peaks at approximately 9.7, 10.4 and 24.8 deg 2-theta. The DSC curve of Form I (FIG. 2) exhibits a melting endotherm at approximately 100°-105° C. The integrated melting endotherm has a heat of fusion of approximately 60 J/g.
The IR spectrum of Form I is shown in FIG. 3.
The solid state 13C-NMR spectrum of form I is shown in FIG. 4.
These data indicate that cabergoline Form I is a crystalline polymorph easily distinguishable by XRD and solid state 13C-NMR techniques. DSC and IR are other two useful techniques to characterize the polymorph. The process of the present invention for producing crystalline cabergoline Form I is characterized by crystallisation from a toluene/diethyl ether mixture. The process comprises dissolving the raw final cabergoline, obtained as an oil through the synthesis described in Eur. J. Med. Chem., 24, 421, (1989), in a suitable amount of a toluene/diethyl ether mixture, preferably about 1:1 mixture. The resultant solution is then cooled at a temperature of from −25° to −9° C., preferably at about −12° C. for 17 hours. In these conditions, a toluene solvate is obtained, named Form V, that may be recovered by common procedures, for example by filtration under reduced pressure or by centrifugal filtration, followed by smoothly drying of the resultant solid. The resultant crystals of Form V are then converted into form I upon further drying. The crystals of Form I of cabergoline prepared according to the process of the present invention have preferably a polymorph purity >95%, more preferably >98%. Toluene solvate form V is also object of the present invention. The x-ray powder diffraction pattern for Form V (FIG. 5) shows a crystalline structure.
The DSC curve of solvate Form V (FIG. 6) exhibits a melting endotherm at approximately 60°-65° C.
The IR spectrum of solvate Form V is shown in FIG. 7. The solid state 13C-NMR spectrum of form V is shown in FIG. 8.
These data indicate that cabergoline solvate Form V is easily distinguishable by XRD, DSC and solid state 13C-NMR techniques. IR, combined with another analytical technique, is another method to identify the solvate.
The solvate V of this invention is a true solvate having a fixed composition of about 0.5 toluene moles per mole of cabergoline.
The oil obtained by purification on a chromatographic column after the final step of the synthetic path according to the preparation described in Eur. J. Med. Chem., 24, 421, (1989) and containing 100 g of pure cabergoline was dissolved in toluene to give 243 g of a cabergoline toluene solution. The solution was introduced into a reactor pre-cooled at −12° C., and 182 g of toluene were added to give a 23.5%. w/w cabergoline concentration in this solvent. After cooling again at −12° C., 362 ml of diethyl ether were added. The mixture was cooled again at −12° C. and stirred at this temperature for about 17 hours. The obtained precipitate was filtered under vacuum and smoothly dried. The resultant crystal solvate form V was identified by XRD, DSC, IR and NMR, data shown in FIGS. 5-8 respectively.
Yield was about 45% (w/w) on the basis of pure cabergoline initial content.
The crystal solvate form V obtained in example 1 was dried at a temperature of from 40° C. under vacuum to 65° C. under vacuum. After drying, the resultant crystal form I was identified by XRD, DSC, IR and NMR, data shown in FIGS. 1-4 respectively. Yield was about 40% on the basis of pure cabergoline initial content. The assayed polymorph purity was >98%.
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text:
Variety, May 1
Wall Street's bullishness on Lionsgate has lifted the stock to another all-time high on optimism over its young-adult film franchises.
The stock rose 35¢, or 1.4%, to $25.16 in trading Wednesday in the wake of an aggressive price target hike by analyst Alan Gould of Evercore to $30 from $24.
Gould also raised his earnings per share estimate for the quarter ended March 31 to 48 cents from 42 cents based on strong new film results, the homevid release of the final "Twilight" and the availability of "The Hunger Games" in the pay TV window.
Sentiment: Strong Buy
Yep, and my Jan $20 calls have tripled to $6. Onward!


text:
Evanger's Beef Lungs Freeze-Dried Dog & Cat Treats, 3.5-oz tub
By Evanger's
Temporarily Out of Stock
Evanger's Beef Lungs Freeze-Dried Dog & Cat Treats, 3.5-oz tub
Beef Lung is a unique single-source protein that is rich in essential fatty acids. Gluten-free, grain-free, and never uses additives or artificial ingredients. Because of the palatability and wholesomeness of these treats, they are excellent for finicky pets or pets with food sensitivities, as well as for use as a training reward or food mixer.
Key Benefits
- Grain and Gluten Free
- Only 1 ingredient
- Nutrient dense
|Item Number
|Country of Origin
|Special Diet
Beef Lungs.
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Evanger's Beef Lungs Freeze-Dried Dog & Cat Treats Customer Reviews
Evanger's Beef Lungs Freeze-Dried Dog & Cat Treats 9 9
My dogs love this. My two dogs are food connoisseurs, and even picky with other freeze dried treats. They love, love, love this stuff. And I like to think it is healthy for them because it gives them organ meats. March 19, 2013
Dogs Likey! Both of my picky eaters like these. I thought the tubs were going to be larger than they really are, it's a small container and the treats are not large size. They're average size treats but nothing your dog will chew on for longer than a minute before its gone. I will definitely order these again. April 26, 2014
Beef Lungs My female F3 doesn't care for them, but my male F2 goes absolutely insane and demands (very loudly lol) them as soon as I get the bag out ( a replacement one that is, because he opened the pantry and destroyed the original one)... So the remainings are in a sandwich plastic bag and hidden very high... September 27, 2013
great natural product Packaging is a lil small but overall the dogs enjoyed them and they didn't upset my pampered allergenic pooch May 10, 2013
Dog likes this a lot good treat for my dog. I would think it is not full of fat or other ingredients I wouldn't want to feed him. November 27, 2014
Makes my dog happy! My dog loves the Texas Hold'em beef lung and I was trying to add a little variety without changing his taste so I bought the Evangers Beef Lung. Texture is a little thicker than Texas Hold'ems but size is smaller. My dog seems to like these treats very well. November 24, 2014
Little one loves it! This is my first time ordering from Chewy. My little one loves beef and lamb lung; however, I received the lung on 11/20/14 and the expiration date is 01/15/15 which is less than two months from today, which is disappointing. Other treats I ordered in this order do have a lot further out expiration date. Aside from this, my little one does love the beef lung but I don't think that he will be able to eat all of it by end date. I was very pleased though with how quickly I received my order as well as the great prices at Chewy's. November 20, 2014
We Love These! My little Mia loved this! It also has good quality ingredients and nothing from China. I highly recommend it! The only complain I have is they are rather large and hard to break up for a smaller dog. September 5, 2014


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Annuities accounted for $1.9 trillion of retirement assets in the U.S. at the end of September, according to data from the Investment Company Institute. The total for all retirement assets reached $21.7 trillion, an increase of 3.9% from the figure at the end of June, the institute said.
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Boston Celtics Vs. New York Knicks At Madison Square Garden
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The Celtics Kevin Garnett scowls at an official as he heads to the... ニュース写真NBAプロバスケットボール,しかめっ面,アメリカ合州国,ケビン ガーネット,スポーツ,ファウル,ベンチ,対戦試合,横長Photographer Boston GlobeCollection: Boston Globe 2013 - The Boston GlobeNEW YORK - APRIL 23: The Celtics Kevin Garnett scowls at an official as he heads to the bench early in the game after picking up his second personal foul. Head coach Doc Rivers stares at left, and a Knicks fans cheers at right. The Boston Celtics visited the New York Knicks for Game Two of an NBA Eastern Conference Quarter Final series at Madison Square Garden. (Photo by Jim Davis/The Boston Globe via Getty Images)


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Some Highlights from Wednesday's WSJTM…
House Approves Bill to Aid States
House members made a rare return to the Capital yesterday, many interrupting vacations during summer break, to approve a $26 billion bill aimed at helping states retain teachers and make Medicaid payments. Republicans mocked the session as theater while Democrats touted their willingness to interrupt election campaigns to save jobs. Download MP3
Alaska's Stevens Perishes in Crash
The longest serving Republican Senator died when a small plane carrying him and 8 other crashed in a remote part of Alaska Monday. Ted Stevens, Alaska's man of the century was 86. Download MP3
The JetBlue flight attendant who allegedly launched into an expletive tirade over an intercom on a plane full of passengers was arraigned yesterday. His lawyer explained that it was two separate run-ins with a rude female passenger that fueled the incident. Download MP3
Also on today's show…
Senator Gave Alaska a Powerful Voice
Boom Makers Say BP Left Them Adrift
Colorado Democrats Choose Incumbent Senator Bennet
H-P Board Surprised Hurd Didn't Go Quietly
Discovering Hats, a New Generation Brims With Anxiety Over Etiquette
Germanwings Flight 9525 focus turns to suicide, who will take over for Harry Reid and the emergence of CrossFit.
Are we too complacent about world events, how to protect yourself from tax fraudsters and whats in your mixed drink.
Germanwings flight co-pilot 'deliberately' crashed plane but questions remain, self driving cars are almost here but only for 1 per-centers and Dean Smith willed $200 to each of his former players.
Jet audio shows one of the Germanwings' pilots locked out of cockpit, Sgt. Bowe Bergdahl is charged with desertion and when two minutes isn't really two minutes.
The search for clues continues in Germanwings crash, a new app hopes to change the face of the 2016 presidential race and the one place where Kentucky basketball is only OK.
Wake up with America's first news – The Wall Street Journal This Morning. Host Gordon Deal and news anchor Gina Cervetti go beyond the headlines with the day's first look at news and business news from the U.S. and around the world; bringing a lively blend of intelligent information, humor, and expert analysis to morning radio.
Gordon Deal Before taking the helm at The Wall Street Journal This Morning in November 2005, Gordon was well-known to New York City radio listeners, having worked at both WINS-AM and WCBS-AM where he honed his writing skills and developed his distinctive on-air reporting style. He also served as New York City bureau chief for Metro Networks where his reports aired on WOR-AM and WABC-AM.
Gina Cervetti has an extensive radio news anchoring and reporting background including several years at Boston NPR affiliate WBUR-FM where she anchored the local production of "All Things Considered" and "Here and Now." Gina is an Associated Press Award-winning broadcaster, whose reports have been heard all over New England, including WRKO Boston and WTAG Worcester. She graduated from Boston University.
Mike Gavin oversees the production of the show which includes coordinating segments with WSJ reporters, editors, and outside newsmakers. He also oversees the sound and content of the show including all music and sound elements. Mike had spent a decade in radio programming and production before finding a home at WSJ Radio in 2007. He lives at the Jersey Shore with his wife and son.


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JPMorgan loss could lead to more support for Volcker Rule
Jeremy Hobson
May 14, 2012 JPMorgan Chase CEO Jamie Dimon responded to questions about bank regulation on this weekend's "Meet the Press."
What to expect from JPMorgan's shareholder meeting tomorrow
Heidi N. Moore
Interview with
May 14, 2012 JPMorgan Chase CEO Jamie Dimon faces shareholders tomorrow after the announcement of a $2 billion loss. He'll most likely get to keep his 2011 pay package, but expect changes in leadership elsewhere in the company.
JPMorgan's loss: More than a blip in the news cycle
Heidi N. Moore
Interview with
May 24, 2012 New York bureau chief Heidi Moore discusses why JPMorgan's loss is a warning that suggests risky practices are taking place at other Wall Street banks.
Explaining the risk behind JPMorgan's loss
Paddy Hirsch
Interview with
May 11, 2012 Senior producer and host of the online explainer series The Whiteboard, Paddy Hirsch discusses the risks involved in JPMorgan's $2 billion loss.
What's an index of credit default swaps?
Paddy Hirsch
May 11, 2012 Big bets on an obscure index lay at the heart of JPMorgan's losses this week. Sr. Producer Paddy Hirsch explains how an index of CDS works.
Weekly Wrap: JPMorgan, what happened?
Kai Ryssdal
Interview by
May 14, 2012 Reviewing the week's headlines on Wall Street and beyond. This week: Oh how the might have fallen -- JPMorgan's $2 billion loss.
JPMorgan takes a $2 billion fall
Mitchell Hartman
May 11, 2012 Huge trading losses by America's biggest bank strengthen advocates of the Volcker Rule and tougher bank regulation.
How JPMorgan's loss may affect European banks
Stephen Beard
Interview with
May 11, 2012 Europe correspondent Stephen Beard discusses what Europe thinks about JPMorgan's $2 billion blunder and how it might impact how European banks do business.
JPMorgan's loss: A sign that Wall Street's mindset hasn't changed
Heidi N. Moore
Interview with
May 11, 2012 New York bureau chief Heidi Moore discusses why JPMorgan's $2 billion blunder is affecting markets worldwide and how big a $2 billion loss really is.
JP Morgan's Loss: The Explainer
Heidi N. Moore
May 11, 2012 How did JP Morgan lose $2 billion on a single bet? Here's some plain English to help understand it.


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3 comments
Meditation on DisplayAs the holiday season fast approaches, one Manhattan store's window display may attract more attention than usual. On November 6th and 7th the Interdependence Project (IDP), a NYC meditation group, will host a 24 hour marathon meditation sit in the store front windows of a downtown interior design store, ABC Carpet & Home. The initiative, headed by IDP founder Ethan Nichtern, aims to bring awareness to the value of meditation in Western Culture and raise funds for IDP. The meditation event, under the slogan "Change Your Mind to Change the World," will be open to the public: Nichtern will be joined by one hundred IDP members who will meditate in rotation throughout the 24 hours. Introductory meditation classes will also be taught free of charge throughout Saturday by venerable teachers, including Roshi [Pat Enkyo] O'Hara and Dr. More »
2 comments
Just This MuchFull attention is both an activity of learning and the actualization of unconditional love. It is this selfless, choiceless love that heals the illusion of separateness, brokenness, and alienation, yielding a gratification, faith and confidence not dependent on external or internal conditions beyond our control. Practice-Life is the dynamic activity of bringing full attention to what is presenting itself most clearly in the awareness for as long as it is there, and with deepening simplicity and joy, knowing Just This Much! –Douglas Phillips, from "On the Cushion: Q & A with Douglas Phillips," Tricycle, Spring 2003 Read the full article: On The Cushion: Q & A with Douglas Phillips More »
1 comment
Zen Mind, Beginner's Mind in the Tricycle Community Book ClubThe Tricycle Community Book Club is discussing Shunryu Suzuki Roshi's timeless classic, Zen Mind, Beginner's Mind. Zoketsu Norman Fischer, former abbot of San Francisco Zen Center, founded by Suzuki Roshi, introduced the book, and will be stopping by to check in on us from time to time. You need to be a member of the Tricycle Community to participate, but joining is easy, and free! More »
4 comments
What is the Right Way to Sit?Different Buddhist schools recommend a variety of meditative postures. Some emphasize a still, formal posture, while others are less strict and more focused on internal movements of consciousness. Tibetan traditions, for instance, advise an upright spine, erect but relaxed; hands at rest in the lap, with the belly soft; shoulders relaxed, chin slightly tucked, and the gaze lowered with eyelids half shut; the jaw is slack with the tongue behind the upper teeth; the legs are crossed. A Soto Zen Buddhist saying instructs us to sit with formal body and informal mind. The common essential point is to remain balanced and alert, so as to pierce the veil of samsaric illusion. –Lama Surya Das, from "The Heart of Buddhist Meditation," Tricycle, Winter 2007 Read the full article: The Heart of Buddhist Meditation More »
4 comments
Just BeJust sitting means just that. That "just" endlessly goes against the grain of our need to fix, transform, and improve ourselves. The paradox of our practice is that the most effective way of transformation is to leave ourselves alone. The more we let everything be just what it is, the more we relax into an open, attentive awareness of one moment after another. Just sitting leaves everything just as it is. –Barry Magid, from "Leave yourself alone!" Tricycle, Summer 2005 Follow us on Twitter and Facebook. More »
4 comments
Practice is not something we do; it is something we areOur lives, like the ocean, constantly change, and we will naturally face great storms and dreary lulls. How, then, to put our minds in a space where practice is always there, whether tumultuous or in the doldrums? It requires a completely radical view of practice: practice is not something we do; it is something we are. We are not separate from our practice, and so no matter what, our practice is present. An ocean swimmer is loose and flows with the current and moves through the tide. More »


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If Justin Bieber's Mom Wasn't A Christian, She Admits She Would Have Aborted Him
All jokes aside, you're trying to decide whether or not to have your own child killed, just remember that he could turn out to be the next Justin Bieber.
Pattie Mallette's position on abortion is clear: Had she not converted to Christianity before getting pregnant as a teen, her pop star phenom son Justin Bieber would have never been born.
But now, with a memoir under her belt and her son's next album dropping soon, the Stratford, Ont., born mother is carving out a niche as an anti-abortion crusader, amid reports Bieber may not be comfortable with it.
The 37-year-old is the new, public face of a short-film fundraising project to raise at least $10-million for American pregnancy centres, which encourage women to go through with a pregnancy, not terminate it.
There were reports Monday that suggested the pop phenom isn't pleased with his mother sticking her neck so far out on such a polarizing issue.
"Justin just is very uncomfortable about political issues – especially ones like abortion that are very divisive," a Bieber "insider" told the Chicago-Sun Times. "He's all about entertaining his fans with his music and not interested in pushing a political agenda. … Furthermore, I don't believe he agrees with his mom on this issue."
Jill Stanek, a prominent American pro-life blogger, said she's skeptical of whether the "insider" is really in tune with Mr. Bieber's feelings about his mother's activism, pointing to a 2011 Rolling Stone interview in which the pop star famously said "I really don't believe in abortion … It's like killing a baby."
There are all sorts of people willing to speculate about what will happen in the 100 years from now because of global warming, but how many are willing to admit that the next Einstein, Martin Luther King or Ludwig van Beethoven have been put to death at the request of his own mother?
Also see...
Making a man believe that his child doesn't exist for decades is an unusually cruel thing to do. But for Tony Trapani, a secret letter he found after his wife...Read More
John Hawkins
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Jailed for Nonpayment of Child Support – But it's Not His Child
The feminists have ratcheted up the laws against men to such an outrageous level that paternity fraud is not just


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Trailer Questions
Hi everyone! I have a questions about my trailers. I have 2 Allegro Appalachian Trails. I grew them from leaves and they've been living in solo cups since last September and I plan on re potting them as soon as I can walk again. I know that they like to be planted in pan pots. I was just wondering if it was possible that there's more than one violet in the cups, or if this is standard for the way they grow since I've never had one before.
This is the first one. It's not in bloom yet, but it's got a few buds on it.
The second plant, and the bigger of the two (though not by much). This one opened a bud this morning:
Also, should I wait until they're not blooming to repot them? Or does it matter?
Your assumption that there is more than one plant in each pot is absolutely correct. In the first photo there is at least 4 plants, and I can't tell for sure but probably the same number, give or take a few, in the second pot.
I would encourage you to separate the plants when you are able and pot them up one plant to a pot. This will allow each plant to reach it's full potential. Besides, the ideal is to have multiple crowns from ONE plant when working with trailers. Repotting into solo cups for a while is okay too. After the plants have a little more size to them you can repot into 5" pan pots, one plant per pot.
If you were entering trailers in a judged show, the ONE plant would be required to have a minimum of THREE crowns. Three plants with one crown would be disqualified.
As far as taking the blooms off or waiting, I would leave them on since there aren't that many. If they seemed to lag behind, you can always remove the buds then.
Now, you are soon to be the proud parent of about 9 trailers!!


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Police track down 6-foot-11, 300-pound robbery suspect
Nathaniel James Lucas-McLean, 35, had been on the run since a Jan. 4 manhunt in Lynnwood, according to the arrest report. Before the manhunt, he was wanted by Brier police in connection with a robbery.
Brier police allege that Lucas-McLean, who is 6-foot-11 and 300 pounds, went to his acquaintance's house and ordered the victim to "go elephant ears," a slang term for emptying one's pants pockets and turning them inside out. Lucas-McLean reportedly held a katana to the man's neck and demanded his jewelry and cash during the Dec. 22 robbery. Lucas-McLean allegedly also showed a handgun and threatened to hurt the man and his family.
The man was rescued when a relative showed up outside and demanded to see him.
On Jan. 4, a Lynnwood police sergeant spotted Lucas-McLean at a motel along 196th Street SW.
The sergeant was in the motel lobby when Lucas-McLean stepped out of the elevator, according to the report. The sergeant reportedly recognized Lucas-McLean from previous interactions and a Brier police bulletin about the robbery.
A chase broke out. During the chase, Lucas-McLean reportedly ditched a handgun and bags of heroin and methamphetamine, which were later recovered.
Police from Snohomish and King counties converged on scene, but Lucas-McLean was not apprehended at the time.
Lynnwood police on Friday did not say how they tracked down Lucas-McLean the day before. He was arrested without further incident, according to a news release.
Lucas-McLean was being held Friday at the Snohomish County Jail for investigation of first-degree robbery, second-degree assault, unlawful imprisonment, first-degree burglary, felony harassment and drug possession. He also had a warrant for a contempt-of-court offense.
Lynnwood police expect to seek additional charges against Lucas-McLean, including being a felon in possession of a firearm, pending evidence testing of the recovered handgun.
He is described in the police reports as a known gang member and career criminal.
Rikki King: 425-339-3449; firstname.lastname@example.com.
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Montville — Tyler Quidgeon completed 10 of 11 passes for 230 yards and three touchdowns and ran six times for 53 yards and a touchdown as Montville High School beat Fitch on Friday night, 65-26.
Montville led by as much as 42-7 in the second quarter.
Buddy Dewaine had five catches for 186 yards and two touchdowns for Montville (3-2) and Jeremiah Crowley ran 14 times for 81 yards and two touchdowns.
Patrick Bogan (1-yard run), Chance Collier (9-yard catch), Xavier Santiago (65-yard fumble return) and Sean Peterson (51 yard run) also scored for Montville. Nick Veillette added a 26-yard field goal and six extra points.
Robert Duncan threw touchdown passes for 69 and 54 yards to Jonathon Johnston for the Falcons (1-4). Duncan also ran for a 1-yard touchdown.
In other games:
• Orrin Parke ran 21 times for 135 yards and a touchdown and Nico Ramos scored on both a run and interception return to pace New London to its 34-14 win over Windham.
New London shutout the Whippets in the second half, 15-0.
Ramos ran for a 34-yard touchdown for the Whalers (2-2) and returned an interception 40 yards for another score. Jose Garcia ran for a 12 yard touchdown, too.
Ashi Harkness returned a fumble 50 yards for a touchdown for New London and Dante Alston and Chase Cook combined on a safety.
Joseph Santiago ran 16 times for 87 yards and a touchdown for the Whippets (3-2). Jack Risley completed 6 of 16 passes for 119 yards and ran seven times for 43 yards.
• Zach Poirier ran 17 times for 134 yards and two second-half touchdowns while the Stonington defense sacked Griswold's Adam Davis 10 times in a 20-6 win.
Poirier ran for 114 of his 134 yards in the second half for the Bears (2-2). Divante White also threw a 5-yard touchdown to Matt Mitchell.
Adam Davis completed 17 of 28 passes for 164 yards and a touchdown for the Wolverines (3-2).
• Jake Mangual threw two touchdowns and ran for another to pace Waterford past the St. Bernard/Norwich Tech co-op, 40-0.
Mangual threw touchdown passes of 25 and 35 yards to Donny Craig for the Lancers (2-3). He also scored on a 1-yard run.
Josef Gustafson (1 yard), Isaiah Jones (5 yards) and Bishmee Sheppard (6 yards) also ran for touchdowns.
The Saints are 1-4.
• Evan Smith scored three touchdowns as the unbeaten Valley Regional/Old Lyme co-op trounced Enfield, 50-7, in a Pequot Football Conference interdivision game.
Smith scored on a 32-yard run, a 27-yard catch, and a 24-yard interception return for the Warriors (4-0).
Billy Buscetto caught a 17-yard touchdown from Phil Cohen (11 of 17 for 77 yards, two touchdowns) for VR/OL. Also, Tyler James scored on a 2-yard run and Jean-Luc Poulard ran for a 22-yard touchdown.
There goes Sen. Formica, down Ritter's Seaside hole in Waterford
EB planning today for tomorrow's growth in Connecticut, Rhode Island
Connecticut, rest of New England expect a flood of claims after record winter
Rain, warmer temperatures raise river level in North Stonington
Chef Dan Barber challenges Connecticut College audience to cook, eat from whole farm, including waste
New trust fund for retiree benefits in Waterford means modest tax increases over time
Lord Foundation marks fifth anniversary of giving in Norwich area
Six early dismissal days proposed for Groton schools to give teachers more training time
Students question administration's response to professor's Facebook post
Groton will need magnet programs to solve racial imbalance, consultant says


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Jeezy to Hit the Road on Seen It All Tour
Brrr! It's about to get cold this fall as the Snowman will be blowing through your city real soon. Rapper Jeezy is set to embark on the Seen It All tour this week.
Brrr! It's about to get cold this fall as the Snowman will be blowing through your city real soon. Rapper Jeezy is set to embark on the Seen It All tour this week.
When Beyonce tapped Nicki Minaj for the 'Flawless' remix, it was no surprise the singer would select the current queen of rap to assist her on the effort -- she's Queen Bey after all. Last month, the dynamic duo performed the track in Paris during the final two shows of the On the Run tour. Now the official video of the performance arrives.
Wiz Khalifa is not going to let an impending divorce from Amber Rose keep him down. The newly-single rhymer will hit the road on his Blacc Hollywood Big Secret Tour later this month.
Rapper Joey Bada$$ is looking for the cash in 2014. The Pro Era leader drops a new track called 'Get Paid' to commemorate his fall trek, the #B4DAMONEYTOUR.
Hip-Hop heavyweights Lauryn Hill and Fabolous will headline this year's Howard University Homecoming concerts in Washington, D.C. Also on the bill, is California rhyme-spitter Dom Kennedy.
OutKast's #ATLast homecoming show in Atlanta this weekend boasts an all-star lineup of hip-hop and R&B's biggest superstars.
Usher closed out the iHeartRadio Festival with an exciting 20-minute set in Las Vegas on Friday (Sept. 19). The R&B crooner also surprised audiences by bringing out his good friend and 'New Flame' co-star Chris Brown.
Nicki Minaj kicked off the iHeartRadio Music Festival with a bang! The Young Money superstar was on an all-star bill that also included her 'Bang Bang' co-star who also performed at the event.
OVO Sound is making big moves. In addition to P Reign's EP and Drake's ongoing performance spree with Lil Wayne, singer PARTYNEXTDOOR will headline his first tour.
Rapper YG has been added to the final leg of the Drake Vs. Lil Wayne Tour.


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OUR OPINION: No time to waste on Asian carp
"Carp creep," it's called:
The first slide in the U.S. Geological Survey's tracking map shows the situation in 1975. Two red dots show the presence of Asian carp in Arkansas, where they were introduced to filter pond water.
By 1985, the fish have moved up much of the Mississippi and Ohio rivers. By 1990, they're into the Missouri.
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|Vintage Pulp
|Apr 1 2015
|Vintage Pulp
|Mar 7 2015
We mentioned a while back that the cheapie tabloid Midnight was printed in Montreal, which made it more of a Canadian than American publication. Above you see a rare cover of Minuit, which was the Canadian Midnight. This hit newsstands today in 1966, and it's basically a duplicate of the Nobu McCarthy cover we shared on this day last year. Well, not an exact duplicate. As you can see by looking at the image on the right, the cover text on the U.S. version says: "I'm wild, wicked, and willing," but on Minuit McCarthy says, "Je dis 'oui' aux hommes," which means, "I say 'yes' to men." The sentiment is the same, but we're reasonably sure both lines were made up by Midnight—and Minuit—editors. Thanks to the website viellemarde.com for this image.
|Vintage Pulp
|Feb 28 2015
|Vintage Pulp
|Feb 22 2015
Above, the cover and many scans from Keyhole magazine published today in 1973. The editors push the envelope a bit in this issue with their glorification of under-17 sex, but as always, the content is just fiction spiced up with photos of a few semi-famous glamour models—all well into adulthood—including Susan Shaw, who was a regular in Keyhole's pages. We have several more issues of thus unique publication and you can find them in our handy tabloid index by following this link.
|Vintage Pulp
|Feb 22 2015
|Vintage Pulp
|Feb 9 2015
Police Gazette sometimes faced a need for Adolf Hitler to star on their covers that surpassed available supplies of art. The February 1956 cover you see above was the first time that particular image was used, but they dug it out again for their January 1977 issue, which you see below, and which we showed you in larger size here. By now you know the Gazette's mission post-World War II was to prove Hitler didn't die in Berlin. In this issue George McGrath—the same writer who usually penned these stories—offers a list of reasons why Hitler was still alive as of 1956. Among them:
In short—and this seems especially appropriate to point out with American news anchor Brian Williams in hot water for alleged on-air lies, and Fox News being laughed at for echoing an obviously fake story about the King of Jordan flying combat missions against ISIS—sloppy or false reporting in America's most popular media outlets has always been a problem. The old tabloids fashioned themselves as maverick truthtellers, and that label, along with some flashy visuals, was enough to attract eyeballs. For today's cable news, the same self-labeling and eye candy visuals work the same way. We will have plenty more from the Police Gazette later.
|Feb 1 2015
Top Secret packs several top celebs onto the cover of this issue published today in 1958, but gives center position to the relatively unknown Elsa Sorensen, the 1955 Miss Denmark referred to here as "that nude model." Sorensen was indeed a nude model—she was a 1956 Playboy centerfold under her own name, and afterward continued to model nude as Dane Arden. Top Secret editors claim to know why multi-million-selling pop singer Guy Mitchell married her, but we don't need their help to figure that out. See below:
And that's all there is from Top Secret today, except to say that for us the most interesting part of the Kitt saga—aside from the tantalizing allegation by Kanter that she "disported herself onstage in a lewd and suggestive manner"—is the fact that she's pasted-up on the mag's cover with Sidney Poitier, when in fact her date at the African Room that night was Canadian actor John Ireland. Poitier was nowhere in sight. We'd love to know why Top Secret tried to drag him in, however obliquely, but we're not counting on ever getting the answer. When you dig through the past, unanswered questions are not the exception, but rather the rule.
|Vintage Pulp
|Jan 11 2015
The uniquely sleazy '70s tabloid Keyhole returns to our website with this issue that hit newsstands today in 1973, filled as always with x-rated fiction in the guise of investigative journalism, and just in time to warm the cockles of male readers' winter-chilled hearts. Do you know when you've got a good tabloid on your hands? When your girlfriend takes a look at the cover, says, "Mouth master, huh?" rolls her eyes, and walks away. Yes, Keyhole has the aforementioned ninja of oral arts Vicci Labist, who wistfully describes embarking on her journey to fellative expertise when she was required—for a gang initiation, no less—to go down on nineteen guys at once.
Later in the issue we meet a group of radicals that have developed an orgy bomb (in gas form, amusingly), we're introduced to resident seer Ixion and his Love-O-Scope, we get to know a hooker who demands that her customers get their penises tattooed with her name, and we hear from a stewardess whose last Middle Eastern layover involved a horny sheik and a pliant slave boy. And that's the tame stuff. We have some scans below and more coming from Keyhole later. If you're interested in the issues we've already posted (or in any of hundreds of tabloids), click over to our handy index at this link. Just remember that looking through Keyhole is bad for your eyesight.
|Vintage Pulp | Sex Files
|Jan 10 2015
The last time we checked in on Top Secret was with their October 1962 issue. Today we're visiting January 1964 and plenty has changed in the intervening months. Foremost—the paper and printing quality have degraded to what surely must have been the lowest standard available at the time, which is why our scans are grainy. But we can still recognize June Wilkinson on the cover, who we're told is retiring from modeling, and inside readers hear from Ursula Andress, Jack Lemmon, Brigitte Bardot, Shirley MacLaine, Mandy Rice-Davies and more.
It would be interesting to do the opposite of everything on this list and see how long it takes our social, family and sex lives to fall apart. Just a thought. Anyway, Top Secret finishes the article with this bomb: "These are by no means the only types of secret swishes but they are the ones the average person is most likely to encounter." So basically, the list is all well and good, but anyone can be gay. To which your average non-Neanderthal would reply, "Yes, anyone can be gay. And?" Well, and the editors of Top Secret suggest that anyone displaying suspicious behavior should be investigated more closely. Hmm… we wonder what depth and form those investigations should take? More scans below.
|Vintage Pulp
|Jan 3 2015
Confidential gives Kim Novak the cover and Lili St Cyr the inset on an issue published this month in 1965. Inside, the editors offer readers mostly lukewarm rehash, as was Confidential's usual approach during its fangless mid-1960's years, but there are also a few interesting tidbits. We learn that Lili St. Cyr took more than thirty Nembutals during her 1958 suicide attempt, yet still managed to survive though as few as three pills can be fatal. Ramfis Trujillo's wild Parisian parties are detailed, including the time he and his entourage shot up the lobby of the Hotel George V. And we find out that Frank Sinatra paid a $400 fine in Spain for disturbing the peace when he blew up after a woman threw a drink on him.
But even if Confidential wasn't kicking ass and taking names in 1965, its visuals were still quite nice, with those impactful black, white and red graphics, and that super hip language that's so much of its time but which is still amazing to read today. Try this on for size: "Call the men in the white coats and get the whacky wagon rolling, your favorite swinging correspondent is ready for Flipsville!" We're always ready for Flipsville, and we're always ready for mid-century tabloids, too. How many of these do we have left in our collection? You wouldn't believe us if we told you. We'd sell some, but how could we possibly part with them? We're stuck with them. And so are you. Twenty-plus scans below.


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Federally Funded Research at Institutions of Higher Education, an E-supplement to GAO-04-31
GAO-04-223SP: Published: Nov 14, 2003. Publicly Released: Nov 14, 2003.
Additional Materials:
- Full Report:
(202) 512-6246
Office of Public Affairs
(202) 512-4800
This document presents the results of GAO's survey of federal higher education grant recipients. To obtain data about the policies of universities and colleges concerning (1) making the results of federally funded research available to the public without delays, and (2) managing financial conflicts of interest, we surveyed these universities and colleges via a web-based survey. In addition, we asked whether access to data from federally funded research has been requested through the Freedom of Information Act (FOIA). The survey covered (1) policies and procedures for ensuring that federally funded research results are made available to the public, (2) views on the advantages and disadvantages of posting final technical reports to an agency's Web site, (3) FOIA requests for research data, (4) conflict of interest and financial disclosure policies, and (5) research funding. We identified the 200 universities and colleges that received the highest amounts of federal research funding in fiscal year 2000. The survey was activated on January 29, 2003 and was available until May 31, 2003. To ensure security and data integrity, we provided each contact person with a password to access and complete a questionnaire. From the 200 survey participants, we obtained 171 useable responses for an overall response rate of 86 percent. A more detailed discussion of our scope and methodology and a discussion of the survey results are contained in our report entitled "University Research: Federal Agencies Need to Better Protect Against Financial Conflicts of Interest" GAO-04-31. We conducted our survey work from August 2002 through September 2003 in accordance with generally accepted government auditing standards.
Mar 26, 2015
Higher Education:Better Management of Federal Grant and Loan Forgiveness Programs for Teachers Needed to Improve Participant OutcomesGAO-15-314: Published: Feb 24, 2015. Publicly Released: Mar 26, 2015.
Feb 27, 2015
Indian Affairs:Preliminary Results Show Continued Challenges to the Oversight and Support of Education FacilitiesGAO-15-389T: Published: Feb 27, 2015. Publicly Released: Feb 27, 2015.
Jan 22, 2015
Higher Education:Education Should Strengthen Oversight of Schools and Accreditors [Reissued on January 22, 2015]GAO-15-59: Published: Dec 22, 2014. Publicly Released: Dec 22, 2014.
Dec 19, 2014
Education and Workforce Data:Challenges in Matching Student and Worker Information Raise Concerns about Longitudinal Data SystemsGAO-15-27: Published: Nov 19, 2014. Publicly Released: Dec 19, 2014.
Dec 16, 2014
Higher Education:State Funding Trends and Policies on AffordabilityGAO-15-151: Published: Dec 16, 2014. Publicly Released: Dec 16, 2014.
Dec 12, 2014
College-and-Career Readiness:States Have Made Progress in Implementing New Standards and Assessments, but Challenges RemainGAO-15-104R: Published: Dec 12, 2014. Publicly Released: Dec 12, 2014.
Nov 13, 2014
Indian Affairs:Bureau of Indian Education Needs to Improve Oversight of School SpendingGAO-15-121: Published: Nov 13, 2014. Publicly Released: Nov 13, 2014.
Sep 24, 2014
Special Education:Improved Performance Measures Could Enhance Oversight of Dispute ResolutionGAO-14-390: Published: Aug 25, 2014. Publicly Released: Sep 24, 2014.
Sep 10, 2014
Department of Education:Status of Prior GAO RecommendationsGAO-14-848T: Published: Sep 10, 2014. Publicly Released: Sep 10, 2014.
Older Americans:Inability to Repay Student Loans May Affect Financial Security of a Small Percentage of RetireesGAO-14-866T: Published: Sep 10, 2014. Publicly Released: Sep 10, 2014.
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text: We had spent wonderful days in Jordan and we have to thank Genevieve and Jalal for their essential contribution to make our stay pleasant. We spent at Genny BB 5 nights (four at the beginning of our trip and one at the end). Their house is located in a strategic and quiet area of Amman, near to highway and stores,... More


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Grilled Pork Recipes
Looking for grilled pork recipes? Find grilled pork recipes including grilled pork chops, grilled pork ribs, and more grilled pork recipes.
Recipe Spotlight
Rosemary Pork Loin
I started growing rosemary in my garden after I discovered this pork recipe. My husband and I think it's restaurant quality, and we look forward to making it after work. —Judy Learned, Boyertown, PennsylvaniaView Rosemary Pork Loin Recipe


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Countertop Heater Sticks On and Plugs In to Warm Up SurfacesBy Bill Esler Posted: 11/15/2014 10:36AM
Heated Stone Products says it has developed a proprietary design and fabrication technology to produce custom, large-format resistive heaters for countertops without set-up or design fees at an affordable cost. The heaters raise the temperature of a countertop by 20 to 25 degrees.
Wood Industry Market Leader: Skip LaBella, Closet AmericaBy Karen Koenig Posted: 11/04/2014 9:10PM
Skip LaBella, president of Closet America, has been named a 2014 Wood Industry Market Leader by Woodworking Network magazine.
Paws & Rest: 1760-style Walnut and Mahogany Veneer Pet BedsPosted by Bill Esler | Posted: 11/02/2014 9:54PM
Well-heeled pets can sleep in peace on Jonathan Charles' playful pet beds. Though as with all fine furniture, there is a price to pay.
Closet Factory Builds Third Homearama Showcase HouseBy Michaelle Bradford Posted: 11/01/2014 8:04AM
Closet Factory Virginia Beach's The Suffolk House - Lifestyle by Closet Factory was built for the Tidewater Builders Association's 2014 Homearama showcase which runs until Nov. 3.
Smart Design: Cabinet Accessories to Maximize SpacePosted: 10/23/2014 8:37PM
Current trending of lifestyles, whether it may be empty nesters, first time home buyers or the economy, have left people with smaller spaces.
Closet Factory Partners with Builder on Homearama ShowpiecePosted by Bill Esler | Posted: 10/16/2014 1:56PM
At Homearama, The Suffolk House, with home storage solutions by Closet Factory Virginia Beach for a home built by Joey Corp., has organizational features on all levels. A video tour shows it off.
Kitchen Cabinet Roll-outs on Rise: RSI Professional Cabinet PCSPosted by Bill Esler | Posted: 10/12/2014 12:22PM
Rollouts in lower cabinets in a kitchen, utility room or any frequently-used home storage area are specified in 92 percent of projects, reports cabinetry manufacturer RSI PCS, citing the NKBA 2014 Kitchen & Bath Style Report.
Sculptural Wall Shelf Storage Assembles RapidlyPosted by Bill Esler | Posted: 10/11/2014 10:13AM
Designer Jaewon Cho assembles his T.shelf T14 (T6 + T8) wall storage system at the j1studio in Los Angeles CA. For more information please visit www.j1studio.com Video produced by Pico Studio.
Audacious: The Fine Art of Wood from the Montalto Bohlen CollectionSalem , MA
CIFM / Interzum Guangzhou 2015Guangzhou
2015 Stiles Executive Briefing ConferenceAtlanta , GA


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Vt. prison truck strikes, kills bearJuly 23,2013BELVIDERE Authorities say a bear was struck and killed by a prison truck on a Vermont road.
WCAX-TV reported that police said the truck was taking a prisoner at about 10:45 p.m. Sunday on Route 109 when the vehicle hit the bear in Belvidere.
No one in the truck was injured, but the vehicle was damaged and had to be towed.MORE IN Vermont NewsMONTPELIER The Vermont Senate on Wednesday gave preliminary approval to new gun restrictions... Full StoryMONTPELIER Lawmakers are considering a scaled-back health care bill that strips out a proposed... Full StoryWASHINGTON Inspired by the popular USDA organic label, House Republicans are proposing a new... Full Story
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- RICHARD'S POOR ALMANACK: On this day 1739, 'Richard Palmer' identified in prison at York Castle as the notorious outlaw DICK TURPIN; IN 1836, Battle of the Alamo begins near San Antonio de Bexar, Texas; 1896, the Tootsie Roll invented by LEO HIRSCHFELD.
- RICHARD'S POOR ALMANACK: On this day in 1472, Orkney, Shetland islands put up as collateral by Norway to Scotland in lieu of dowry for MARGARET OF DENMARK on her marriage with JAMES III, king of Scotland; 1962, JOHN GLENN first American to orbit Earth.
- TOMORROW'S HEADLINES TODAY: City mayoral candidates debate campaign issues; Hartford, Conn., woman still missing; Neal Goswami reports attempts to legislate suicide; local woman loses 100 pounds through TOPS program.
- RICHARD'S POOR ALMANACK: On this day in 1878, JOHN TUNSTALL murdered near Lincoln, New Mexico, by the outlaw JESSE EVANS; in 1930, ELM FARM OLLIE first cow to fly in aircraft, first to be milked airborne; 1955, nuke test WASP; '79, snow in Sahara.
- TOMORROW'S HEADLINES TODAY: Rutland Herald News Editor Alan J. Keays and staff writer Gordon Dritschilo discuss stories planned for the February 18, 2015, edition of the newspaper: Winter budgets maxed, legal marijuana, Springfield bank job, USPS slowdown
- RICHARD'S POOR ALMANACK: On this day in 1249 AD, ANDRE of LONGJUMEAU is dispatched by LOUIS IX of France to meet the KHAGAN, ruler of the Mongol Empire; in 1804, during 1st Barbary War, STEPHEN DECATUR scuttles the pirate-held USS Philadelphia in Tripoli.


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Northwoods League: Stingers hit 3 HRs, but fall to Alex
ALEXANDRIA -- Kenny Roberts hit his league-leading 12th home run, but the Willmar Stingers fell to the Alexandria Beetles 9-7 on Wednesday in Alexandria.
The Stingers fell to 8-6 and are tied for second in the Northwoods League North Division second half. They play Alexandria at 7 p.m. today at Bill Taunton Stadium in Willmar.
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© Jemella LTD
The original ghd styler
The original multi-award-winning ghd IV styler is the perfect tool for quick, effortless straightening and easy curls and waves. Suitable for all hair types and lengths. A brilliant all-rounder for everyday styling.
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Rated 4.5 out of 5 by 2965 reviewers.
Rated 5 out of 5 Nothing compares to GHD The ghd is really easy to use, heats up super fast and with just one stroke you achieve greatness in silky straight & shinny hair. I had tried other products & they do not even compare! 10 November 2013
Rated 4 out of 5 Impressive customer service Latest straighteners were a replacement for pair with one plate which stopped working. Returns procedure quick & simple, kept informed & replacement sent promptly. Cannot fault the customer service - if only all companies were the same! 10 November 2013
Rated 5 out of 5 by kellyann Is brilliant. does the job. Ghds are really good. The last pair I had broke and couldnt get them.fixed as I had lost the receipt :-( however I just hadto buy new ones. Other brands are also quite gd but nothings beats ghds for quality and size and how well they actually straighten my hair without drying it out. 10 November 2013
Rated 1 out of 5 by mclmcl q Not very good compared to my last hair straighteners 09 November 2013
Rated 5 out of 5 by Punk Happy out so far I have it a couple of weeks and I've used it twice and it hasn't disappointed. 09 November 2013
Rated 5 out of 5 by Rob11 Birthday gift for partner. The hair straighteners arrived the next day after the order was placed. A few days later she received them on her birthday and began to use them right away. In under a hour she had finished straightening her hair which is the shortest time i have ever known it to take her. The only comment she had was that it is a shame there was no stand included to rest the straighteners on. I would definitely recommend ghd. 09 November 2013
Rated 1 out of 5 by Sadcustomer Disappointed I have used GHD straighteners for many years and had no hesitation in going out to purchase another set when mine broke. However, I have been extremely disappointed in this product which does not give the same finish as my previous set. It requires going over my hair many times and still not achieving a good end result. 08 November 2013
Rated 5 out of 5 by lilly51 They're simply the best My hairdresser introduced me to my first GHD's way back in 2002, and I've only just replaced them. Pricey maybe, but you really are getting excellent quality straighteners, and they've certainly been a very good purchase. They leave my hair soft, shiny and oh so sleek and smooth. I don't use them every day, only when I wash my hair. You just don't need to. They're quick to heat up, very easy to use, and I won't use any others now. A girl simply cannot be without her GHD's. 08 November 2013
Rated 3 out of 5 by DeniseJ Dont seem as good! Just bought the silver ghd iv styler in a hurry as was going away. They dont seem as good as the regular black ones my daughter has had for a few years, for some reason - but persevering with them! 07 November 2013
Rated 4 out of 5 Good product This product is okay to be honest gets results and hair smooth yet as I have curly hair i can't get the exact result I want with this exact product but if your hair is normal or fine or wavy then they are great 06 November 2013
Rated 5 out of 5 by Ozsmurf Love my straightener. Now to find a great product for my hair as straightening does tend to dry the ends. :) I love it tho. :) Awesome!! I love my straightener and do glad I bought it at bargain price. Thank you Ghd!! 05 November 2013
Rated 5 out of 5 by DebKB Well worth the money My first ghd styler lasted me 10 years, ghd are well worth the money. Love, love, love my styler! 05 November 2013
Rated 3 out of 5 by Chloe789 Bit disappointing I replaced my old ghds which were ten years old with these, thinking I'd get sleeker results, but they don't seem to close properly and though they straighten my hair, it doesn't compare to how well salon ghds work on my hair and they aren't any better than my old ones, other than they make a noise when they are hot! 05 November 2013
Rated 5 out of 5 by lozaa95 Great Product Excellent product, no faults about it. I love it as it is the only product that can style my hair properly. 05 November 2013
Rated 5 out of 5 by Dello Fabulous Wish I had got these years ago. Love them, easy to use, quick and excellent results. 03 November 2013
Rated 3 out of 5 by Onchie Gap on bettween the plates My GHD stopped working after many many years. I went to replace it and the new one had a gap between the plates which didn't do a good job as my old one. I had to press it very hard for the gap to close other wise it won't grab my hair. It is better than many hair straightners but might look into getting another brand after as I feel the quality isn't the same. 02 November 2013
Rated 5 out of 5 by Sara786 Brilliant I got this for myself as a treat, Best thing I've bought well worth the money 01 November 2013
Rated 5 out of 5 by Eloise GHD have given me more time to have fun! Love my GHDs - cannot think why I have waited so long to purchase some. The Rolls Royce of straighteners! 01 November 2013
Rated 4 out of 5 by daisylee like the cut out feature if product left on only issue is that this set of ghds don't seem to get as hot as my previous pair so i do have to spend more time straightening my hair 31 October 2013
Rated 5 out of 5 by ShirleyMc Excellent straighteners Very pleased - as always - with the service. Would never consider buying anything other than GHD's. Great results and excellent customer service with any problems within guarantee. 31 October 2013
Rated 2 out of 5 by Sam71 Straighteners Not as good as my original ghds. Hair wont straighten properly 31 October 2013
Rated 5 out of 5 by Claire87 Best hair straighteners My ghd's were dispatched incredibly quickly. They are the only type of hair straighteners which can tame my hair as it is quite curly and frizzy naturally and I am always pleased with the results. 31 October 2013
Rated 3 out of 5 by Alemap a disappointing product this is my second ghd straightener - this one is not as good as the first one I had - this one does not seem to straighten my hair as easily, takes much longer as each section of hair needs to be straightened multiple times and the end result is unsatisfactory. my hair is not as smooth and silky as it was with the previous ghd straightener. my first straightener was a limited edition breast cancer straightener purchased approximately 3 years ago and I loved it and recommended it to all my friends, but when it stopped working I bought this replacement, which I am not happy with. 30 October 2013
Rated 5 out of 5 by Einnan Excellent quality and smooth efficiency. When I changed from a cheaper straightener, I did not expect to be so impressed by the overall quality and efficiency of this styler. I love it - the little noise it makes when it's ready (heats up really quickly,too) and when I'm finished, I love the flashing light to remind me it's still switched on!! I had to save my pennies to buy this styler, but it's worth every penny! 30 October 2013
Rated 5 out of 5 by ALIq slim and neat great features easy to use terrific results gets to right temperature hair is left smooth and silky style lasts for days 30 October 2013
Rated 5 out of 5 by Bubblegum Light weight This product has simple features.very light weight. Would recommend to others 30 October 2013
Rated 4 out of 5 by Nettie good I have only used it a few times. I have fairly short hair. It has been good so far. 29 October 2013
Rated 5 out of 5 by Puddycats2 Couldn't live without them as nothing else compares to them :) This is the only product that can tame my "wild" frizzy hair! I love them so much, I have to have a spare pair close by..... Just in case :) 28 October 2013
Rated 5 out of 5 by Heaf24 Excellent Luv it so this is my second one. Didn't hesitate in purchasing another 27 October 2013
Rated 1 out of 5 by spongolos does not straighten hair not half as good as my previous one I had for years which unfortunately I dropped on the carpet and the ceramic came apart. I actually sent you an email before I received this one from yourselves as my sister purchased one as well and she is not happy either 26 October 2013
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Like I want
A cookbook?
Subtlety works for no one and cookbook won't work for you. Send your loved ones a hint to make sure you get the gift you really want this year. Don't be shy.
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Unfortunately, {0} doesn't want to receive emails from ghd, so we cannot send them your hint. But don't worry, here's a couple of ways to get what you want, including:
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Silhouette Of Woman Walking Alone Stock PhotoLoneliness,Walking,Parma - Italy,Christmas,Italy,Photography,One Person,Rear View,Silhouette,Adult,Adults Only,Celebration,Color Image,Dinner Party,Full Length,Horizontal,Incidental People,New Year,On The Move,One Woman Only,Outdoors,People,Salsomaggiore Terme,Tree,Tree TrunkPhotographer Ivano Bettati Photography - ItalyCollection: Moment (c) Copyright Ivano BettatiFeasts of Christmas and New Year spent with friends and relatives.


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Management Team
PsiOxus Therapeutics has a highly experienced management team.
Chief Executive Officer: Dr John Beadle
Dr John Beadle was Entrepreneur in Residence at Imperial College London, where he helped to establish Myotec Therapeutics as a spin-out business. He became CEO of Myotec in late 2008, rapidly securing seed financing followed by a £5.6 million series A funding round from Imperial Innovations and Invesco Perpetual in early 2010. During this time, John was also Executive Chairman and CEO of Hybrid Biosystems, securing further seed financing for this Oxford based start-up. In 2010, John's leadership of these two private companies led to their combination to form PsiOxus Therapeutics Ltd. John was previously the co-founder of the vaccine company PowderMed. In 2004 he helped to raise £20 million from leading UK and US Venture Capital Funds and was then Chief Medical Officer and board director leading to the trade sale of PowderMed to Pfizer for over US$300 million in 2006. John has previously held roles at PowderJect, Pfizer and Glaxo SmithKline where he was most recently VP of Global Medical Operations. John was trained in Medicine at the University of Witwatersrand and received his MBA with distinction from the London Business School.
Chief Financial Officer and Company Secretary: Theodora Harold
Theodora Harold is a chartered accountant with significant experience as a Chief Financal Officer and Company Secretary with early stage and growing companies in the biotech sector. She has a background in both industry and corporate finance with 16 years of experience in SMEs in the biotech and hi-tech sectors and has held roles with Cytomyx Holdings plc, RioTech Pharmaceuticals Ltd, OrthoMimetics Ltd, Hybrid Biosystems Ltd, Myotec Therapeutics Ltd and Mission Therapeutics Ltd. Prior to this, Theodora trained with PricewaterhouseCoopers and read Classics at Trinity College, Cambridge.
Chief Scientific Officer: Dr Kerry Fisher
Dr Kerry Fisher is a Scientific Founder of Hybrid Biosystems Ltd. As well as serving on the Board he has held roles as Chief Scientific Officer and CEO. He is a gene delivery specialist working with therapeutic viruses for the treatment of cancer and for vaccination against infectious disease. His areas of interest include pharmacology and medicinal virology, with a particular interest in the modification of viruses for clinical use. Kerry achieved a 1st class undergraduate degree from the University of Aberdeen and completed his PhD in 2001 at the University of Birmingham. Since graduating Kerry has published over 40 articles and won several awards for his work. As well as his role as Chief Scientific Officer at PsiOxus Therapeutics, Kerry also holds an academic position as Lecturer at the University of Oxford.
Chief Operating Officer: Priya Mande
Priya Mande has over 20 years of experience in the pharmaceutical and biotech sector. She was previously at PowderMed responsible for vaccine immunotherapeutic projects, collaboration with academic institutions and Joint Ventures with other Pharma companies targeting influenza, chronic viral diseases and cancer. Priya was also the Vaccine Research Project Leader for Influenza at Pfizer before becoming COO of Hybrid BioSystems in 2009. She has previously held various roles within Glaxo Wellcome and Glaxo SmithKline over a 12 year period where she was most recently senior Director of R&D Business Projects. Priya studied Biochemistry at Brunel University, received a MBA with distinction from the London Business School and has a Diploma in Company Direction from the Institute of Directors. Priya has received several awards for project leadership including an international collaboration award at the 26th US Army Science Conference.
VP of Pharmaceutical Development: Dr Jeetendra Bhatia
Dr Jeetendra Bhatia has over 15 years of experience in pharmaceutical development & manufacturer. His areas of interest include development of novel therapeutics, GMP manufacture and formulation. Jeetendra has developed both recombinant and microbial vaccines for the treatment of cancer and other infectious disease and has published scientific articles. Jeetendra completed his PhD in 1999 at the University of London, whilst working for the Cancer Research UK, Department of Oncology at The Royal Free Hospital, London. Whilst at the Royal Free Hospital, Jeetendra set up a GMP facility which manufactured a cancer therapeutic used for a Phase I/II clinical trial. The facility was later ISO9001 certified by the MHRA. He has previously held roles as Senior Development Manager at Avidex Ltd and Emergent BioSolutions where he was most recently the Head of Process & Analytical Development before moving to PsiOXus in May, 2011.
Chief Medical Officer: Dr Christine Wilkinson Blanc
Dr Christine Wilkinson Blanc has over 20 years of clinical research and medical affairs experience in the pharmaceutical industry, working in the fields of oncology and haematology. She has collaborated on prominent clinical development programs including docetaxel and irinotecan at Aventis/Rhone-Poulenc Rorer, bevacizumab at Roche and ridaforolimus at Ariad. She also served as Medical Director at GE Healthcare contributing to the development and marketing strategy of diagnostic and functional imaging agents and at Aventis International, where she pioneered the implementation of oncology research programs in Eastern Europe, Latin America and Asia. Most recently Christine operated her own company, consulting to the pharmaceutical and biotechnology industry on a range of oncology programs. Dr Wilkinson Blanc studied Medicine at the Universities of Lyon and Lille. She specialised in Medical Biology, has been Chef de Clinique in Clinical Haematology at Lille University Hospital and also holds a Master of Science in Immunology.
Senior VP of Research and Development: Dr Brian Champion
Dr Brian Champion was previously Executive Director and Head of Immunology for Pfizer's Vaccine Immunotherapeutics Research Unit in La Jolla, California. In this role Brian led the immunology team providing expertise and immunoassays for all Pfizer vaccine projects, including therapeutic T-cell focused vaccines for cancer, antibody focused vaccines for several different diseases as well as several prophylactic infectious disease vaccines. He was also a member of the leadership team as well as Program Lead for an anti-IgE therapeutic vaccine for allergy/asthma. Prior to this role, Brian was Site Head for Pfizer Vaccine Research in the UK. Before joining Pfizer, Dr Champion was Chief Scientific Officer for Lorantis and Celldex, Cambridge, developing protein and DNA-based, antigen-specific immunotherapeutic approaches to a variety of immunological diseases, including therapeutic vaccines and immunotherapeutic biomolecule approaches for cancer, infectious diseases, allergies and autoimmune disorders. Prior to Lorantis, he was with Glaxo and GlaxoWellcome (UK and USA) for 13 years, focusing primarily on target discovery and validation research for autoimmune, allergic and bone disorders.
Director of Biology: Dr Alice Brown
Dr Alice Brown joined PsiOxus in 2012 having carried out her post-doctoral research in the Immunology and Physics departments at Imperial College London. During this time she published several key papers on the biology of Natural Killer Cells and was awarded a Wellcome Trust public engagement grant for science communication projects. Alice achieved a 1st class degree in Biochemistry from the University of Bristol with a year in Industry at GSK and was awarded a PhD in Biochemistry from the University of Bristol in 2009.
Chief Business Officer: Dr Hooshmand Sheshbaradaran
Dr Hooshmand Sheshbaradaran has over 20 years' experience in the pharmaceutical and biotechnology sectors in drug development, marketing, business development, financing and executive operations. His previous positions include co-founder and CEO of Niiki Pharma, an oncology company with a pipeline of clinical stage anti-cancer agents. Niiki Pharma was acquired by Intezyne Technologies Inc, in 2013. Previously, he has held various senior global marketing and business development executive positions in leading pharmaceutical companies including Global Director of Oncology Business Development at Roche and Global Director of Oncology, New Products Marketing, at Pharmacia/Pfizer. During his business career in the pharmaceutical industry he has participated and closed on M&As, global licensing deals and numerous regional and university deals. Dr Sheshbaradaran earned his PhD in Virology and Immunology from the Karolinksa Institute, Sweden.


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Where is Malolotja or Kwa-Zulu-Natal ?
A friend gave me a small plant of Aloe marlothii. I'm curious to know if it is winter-growing, or summer-growing, etc.; what is the climate like where if comes from. Does it expect water in cool weather or hot, or variable.
I found one Web site that describes it as winter-flowering, and part of the flora of Malolotja. Another Web site describes its best season as winter and spring, with at least some plants coming from Kwa-Zulu-Natal.
Both KwaZulu-Natal and the Transvaal and Swaziland , which are its home ranges are summer rainfall regions , so one should water during summer and give only a little water in winter. It was named after Professor Marloth , who was one ot the most famous S.A. botanists. It grows in the Malolotja National Park but is endemic to almost the whole of the ex Transvaal Province.As with a lot of our plants it should not be fertilised , give it some compost rather and ensure that it has well drained soil and a full sun position. Aloes often grow on hill slopes in the wild (ie well drained spots). Aloes are remarkably adaptable to different environments and often thrive on neglect. They are often planted at traffic intersections over here , where they get very little if any care.


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My daughter and son-in-law just had a baby last week. We are thrilled. But we won't be able to see the baby or hold her any time soon. We won't be able to take over little gifts or help out with housework or babysitting.
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Customers, former employees honor Walt, retiring owner of Willmar landmark business
WILLMAR -- A Willmar business owner who strove to give his young employees a good start in life discovered that what goes around really does come around.
Employees current and past were among the hundreds of well-wishers making sure that Walt and Raeanna Gislason got their new lives as retirees off to the best start Tuesday.
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Some athletes from the Special Olympics share their stories with WESH 2 News anchorman Jim Payne.
Special Olympics stars visit WESH
Athletes share stories with Jim PayneUPDATED 11:32 AM EDT Apr 13, 2013
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