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New research on melanoma risk in red-haired people
Article first published online: 4 MAR 2013
DOI: 10.1002/cncr.28013
Copyright © 2012 American Cancer Society
Volume 119, Issue 6, page 1118, 15 March 2013
Additional Information
How to Cite
Printz, C. (2013), New research on melanoma risk in red-haired people. Cancer, 119: 1118. doi: 10.1002/cncr.28013
Publication History
- Issue published online: 4 MAR 2013
- Article first published online: 4 MAR 2013
- Abstract
- Article
- References
- Cited By
Alack of natural protection against ultraviolet (UV) radiation in people with red hair and fair skin has long been considered a risk factor for melanoma. However, according to researchers at Massachusetts General Hospital (MGH) in Boston, another factor may contribute to the disease: the red/blond pigment itself.1
The finding helps explain a mechanism that may lead to the disease in people with this skin pigment, called pheomelanin, says David Fisher, MD, PhD, chief of the department of dermatology at MGH and senior author of the study. Pheomelanin is less effective than dark melanin in blocking UV damage. According to the study authors, additional research has shown that increased nonmelanoma skin cancer risk is limited to areas that have been exposed to the sun, but melanoma risk can be associated with areas of the skin that are not sun-exposed.
Oxidative Damage May Be Underlying Cause
In the MGH study, investigators compared 2 groups of mice: 1 with the dark-skin pigment and the other with the red-hair/fairskin type. They then activated the melanoma-associated form of the BRAF oncogene in patches of the animals' skin pigment cells, assuming that UV radiation would need to be used to induce melanoma. Instead, they found that within months, onehalf of the mice with the red-hair/fairskin type had developed melanomas whereas only a few of the mice with the dark-skin pigment had.
Because no UV radiation was involved, researchers began to wonder whether the pheomelanin pigment itself might be carcinogenic. As a result, they tested a group of red-haired/fairskinned mice in which all pigment production was genetically disabled ("albino redheads"). They found that removing that pigment pathway protected the mice from melanoma formation. They later discovered elevated levels of a type of DNA damage typically produced in the skin of mice with pheomelanin but not in albino redheads, which supports the theory that oxidative damage may be the underlying cause of red pigment-associated melanoma.
Dr. Fisher says more research is needed to determine safe and effective ways to apply this knowledge to improve melanoma protection, but that antioxidant treatments may potentially help reduce risk.
- 1An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature. 2012; 491: 449-453., , , et al.


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How Long Hep B Vaccine Lasts
Here's a taste of what TheBody.com has to offer on this topic:
Ask the Experts
Hep B VaccinationI was wondering how long a hep b vaccine lasts for. I got mine 10 years ago and was wondering if it was something that needs to be done again. Thanks
Response from Benjamin Young, M.D., Ph.D.
Rocky Mountain CARES...If your 10 years out from your vaccine, most would recommend a HBV booster shot. BY Read more »
Hep B vaccination and Hep B surface AgIs it possible to get a positive Hep B surface Ag if I do a blood test within 2 weeks of receiving... Read more »
Hepatitus a abd bHow long are the vaccinations good for? THX Read more »
Vaccinations and HIV...Hepatitis A is usually not serious but it can be for someone with a weakened liver. This includes people who are infected with hepatitis B or C. Two hepatitis A vaccine shots can protect you for about 20 years. Hepatitis B can cause serious... Read more »
Hepatitis B FAQs for the Public...Overview Statistics Transmission / Exposure Symptoms Tests Treatment Prevention / Vaccination Pregnancy and Hepatitis B Overview What is hepatitis? "Hepatitis" means inflammation of the liver. Toxins, certain... Read more »
Hepatitis A FAQs for the Public...Hepatitis is also the name of a family of viral infections that affect the liver ; the most common types are Hepatitis A, Hepatitis B, and Hepatitis C. What is the difference between Hepatitis A, Hepatitis B, and Hepatitis C? ... Read more »
Hepatitis B: The Other Hepatitis Virus...significant problem for many people with HIV, but it isn't the only virus that can cause hepatitis (inflammation of the liver). HIV/hepatitis B virus (HBV) is another common co-infection and, like HIV/HCV co-infection, can cause severe liver... Read more »
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Hep Question
Posted by Anonymous, 2 Replies...I was tested neg for HIV but now I am worried about hep b cause I Am in Asia and hep b is pretty common here according to the CDC. Since I always use condoms is there reason to test Read more »
Re jamie hep vaccine
Posted by Anonymous, 1 Reply...Hi Jamie, if you were vaccinated in school,im sure it was for hep B , I knoww is one for hep A but in school it would have been hep B ,so i wouldn't worry about that, As for me I never was vaccinated Read more »
Any other guys out there had Hepatitis-B??
Posted by MarkyMark, 9 Replies...in the gay comminity, all I ever heard about was HIV, and furthermore I always practiced safe sex! If I had known there was a vaccine to prevent this altogether I would sooo have done it PERIOD!. I would really appreciate ANYONE out there that... Read more »
Hep B Vaccine affecting ELISA?
Posted by crazy_person, 1 Reply...could cause HIV RNA levels to increase, showing an elevated viral load for up to 4-6 weeks. My question is this - would the Hep B vaccine affect the HIV ELISA causing either a false negative or a false positive result? I also read that the ELISA... Read more »
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When to divide Clivia?
The pot my 10yr.old Clivia is in seems to be getting too small as many roots have come to the top of the soil level. It is a large plant and should be divided and re-potted.
When is the best time to do this?
Also, will the Clivia be ok under a 6ft. eave during the winter? We do get frosty nights here. What is the max. low temperature for it?
Thank you for responding.
Hi Helga,
You can divide anytime. Nov./Dec.is probably best, since it is dormant.
My outdoor Clivias tolerate morning temps for a couple hours down to the low 20'sF during our 1-2 weeks of "cold" here in the central valley of CA. You can cover them with burlap or string some regular Christmas lights around them for a few degrees additional warmth if necessary.
take care,


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Le Mephisto: Le Mephisto, Cahors
Simple food, at a good price, done well. The owner is very friendly - seeing my friend's amnesty top, he gave us free drinks. When he offered us the meat laden day menu, and I explained that I didn't eat meat or fish, he tore off some paper from his pad, 'Voici, votre repas'! I did get an omelette, fortunately. He also made the requisite animal noises to illustrate what, say, un canard was. Great fun.
Favorite Dish: My friend recommends the stuffed mushrooms.
- Budget Travel
Le Balandre: Gourmet Eating
This is a rated Michelin restaurant especially recommended for its local fare. As would be expected in a superior restaurant the staff, the presentation and the chef are exceptional. When we were here the value of the dollar was at its peak and at dinner we ate and drank heartily. Of course we were also staying at the hotel. They chose the Cahors wine for us. I cannot find a picture of the interior. Lunch is of course cheaper and if it were not raining we would have had that outside
Favorite Dish: Everything but especially the lamb and of course the local wine. It is a little sturdier than the nearby Bordeaux, full-bodied, not full of tannin like a Chianti. We are not experts but we have chosen it elsewhere (when it can be found). The latest price (2008) for a 3 course meal is 60 euro. Even then (1993) the meal with wine was greater than the room rate.
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Nandini Bali Resort & Spa Ubud
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... most known for the book/movie Eat, Pray, Love. It has become quite a mecca for both legit and wannabe yogi's, trying desperately to find some peace of mind, and maybe find some meaning in the continuing cycles around the sun.
For me, I had been here almost 4 years ago on what was a very different tour through the paradise of Bali. Not much had changed. Just a few more shops selling expensive clothes to stretch and sweat in. The local vibe was a nice ...
Balinese celebrations in Ubud
... working their way to the right. Some were used for prayer, some for washing and others to simply just stand in front of whilst lighting an incense stick on the hundreds of offerings on the pool edge. It was amazing to witness this Hindu tradition on a site that has been used for the same purposes from 962 A.D.
On the way back we passed a magnificent rice terrace which was so ...
24 Hours From Ubud
... the blasted form, just so you can finally leave the airport - shades of Tom Hanks, anyone?
As is my wont in situations like these, I whack on some dance music and turn the iPod (other mp3s are available) up to 11. This invariably gets me bobbing to the beat. Now, I would like to state here that the airport is plastered in all sorts of official signs, mostly saying that we will all go to prison if we don't enter the country legally ie it's their way ...
Bali, Indonesia, my 34th country
... energy and good people. The beach isn't far away, so we put in some surfing with free lessons, while I get to try my gopro skills on the board.
Although the kids had great energy, their mountain of hair revealed another story when it came time to work for our free room and board, so we rolled up our sleeves and got the whole group active.
The garden was not yet fully developed and the entire place smelled very earthy. I helped them set up ...
Exploring Ubud
... tell that we were in a touristy area and it wasn't quite what we had pictured. Regardless, we enjoyed our walk and had been out for a few hours. We picked up a magnum on the way back and had fruit back at our place for lunch.
In the afternoon, we walked back into Ubud to browse the shops. We had seen some blankets we liked in Banjar at the Hot Springs and wanted to find out if we could get one in Ubud. We started ...


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Our People:
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Gabriele Fuldauer
Music Theory, B.M., M.M./Diploma Piano Performance and Pedagogy and Organ, Academy of Music and the Performing Arts, Frankfurt, F.R.G. Additional organ, piano, theory, voice and comprehensive music studies at Dr. Hoch's Conservatory and Ev. Church Music School, Frankfurt. Principal teachers include Wolfgang Hees, piano; O.J. Burba, organ; Mark Opeskin, Theory; Bernhard Wetz, Department Head/Director of Studies, piano pedagogy. Participated in Orff Schulwerk workshops at Cleveland State University. Organist and Chime Choir Director at St. John Lutheran Church, South Euclid, Ohio. Eurhythmics, Chime Choir, music understanding classes instructor with the Broadway School of Music and the Arts, Cleveland, Ohio. Frequent recitalist as both soloist and accompanist. Member AGO. Appointed to faculty, 1995.
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Mike Birbiglia's "Sleepwalking Through Christmas" Card
birbigs picked a winning design in their print & packaging design contest. For just $211 they received 79 designs from 61 designers.
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Graphic design made easy
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"Photographs by Brett Weston: Recent Gift from Christian K. Keesee," Fred Jones Jr. Museum of Art, The University of Oklahoma. Norman, Oklahoma. January 27-April 1, 2007.


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Systematic reviews to support evidence-based medicine, 2nd editionTaylor and Francis 2011; US$ 39.95
Authoritative, clear, concise, and practical, this highly acclaimed book continues to be an essential text for all medical, surgical and health professionals who want to have an easily accessible, quick reference to systematically reviewing the literature. Learn about the key steps to reviewing the literature Carry out your own reviews with... more...
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Joseph Gordon-Levitt is now locked in for the role of Johnny in "Sin City 2 : A Dame to Kill For", as reported earlier today.
The actor has now issued a statement in relation to snaring the role, and the studio has issued a press release confirming the casting.
"I love how the first movie uses VFX, not to make fake things look real, but to create a heightened world unburdened by the look and feel of reality. Plus, nobody makes a badass like Mr. Rodriguez."
And the press release from Dimension Films…
New York, NY January 7, 2013 – Dimension Films announced today that Joseph Gordon-Levitt (LOOPER, THE DARK KNIGHT RISES) is joining the all-star cast as one of the lead characters in the highly anticipated SIN CITY: A DAME TO KILL FOR. The film is the follow up to co-directors Robert Rodriguez and Frank Miller's 2005 visually groundbreaking film, FRANK MILLER'S SIN CITY. Other major casting announcements will continue to follow.
Gordon-Levitt will play "Johnny," a cocky gambler who disguises a darker mission to destroy his most foul enemy at his best game.
"Johnny is a new character in the Sin City world and we are excited for what Joseph will bring to the role," said Rodriguez and Miller.
Gordon-Levitt most recently wrote, directed and stars in DON JON'S ADDICTION which will premiere this month at Sundance and also stars Scarlett Johansson and Julianne Moore.
SIN CITY: A DAME TO KILL FOR weaves together two of Miller's classic stories with new tales in which the town's most hard boiled citizens cross paths with some of its more repulsive inhabitants.
The ensemble includes already announced original cast members Academy Award® nominee Mickey Rourke as "Marv," Jessica Alba as "Nancy," Rosario Dawson as "Gail," and Jaime King as "Goldie/Wendy" with new cast members Dennis Haysbert as "Manute," and Jamie Chung as "Miho". Production is underway at Rodriguez's Troublemaker Studios in Austin, Texas.
The original SIN CITY broke new ground with its iconic stylish look. SIN CITY: A DAME TO KILL FOR will not only bring fans back to the world that Miller and Rodriguez created, but also add a new dimension by bringing their unique visual style to life in 3D.
SIN CITY: A DAME TO KILL FOR was developed by Frank Miller based upon his graphic novel, with a screenplay by Miller and Academy Award® winner William Monahan (The Departed).
The film will be released by Dimension Films in the US and Canada on October 4, 2013 and is produced by Robert Rodriguez's Quick Draw Productions, Aldamisa, AR Films, Miramax and Solipsist.
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product details-Tab
Take the guesswork out of rice preparation!
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Perfectly sized & cooks rice perfectly!
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Comments about Aroma ARC-914S 4-Cup Cool-Touch Rice Cooker, 1 ea:
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Bottom Line Yes, I would recommend this to a friend
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Converting our family area into a bedroom
Daphne TeoJanuary 22, 2013
As I intend to convert our family area into a bedroom, I'm looking for suggestions to closeup the part stairs and part empty space. I've considered walling or glassing up the space but it's not aesthetically pleasing to the eye, help! The area is 13 feet by 6 feet.
For the empty space, you could maybe try some wooden shelving. Very useful and if installed properly, very elegant.
Daphne Teo
will you be able to do a simple sketch so I can understand how a wooden shelving can look elegant. my other concern is, is this practical?


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I have a 4 year old to stop having accidents???
My 4 year old is suppose to be completely potty trained...But lately she has been having lots of accidents. She dont do it at school...But the moment she gets home. It is like...
Started by Carrie on 09/04/2009 in Moms With School Age Kids
Last update on 09/14/2009 by Carrie


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I have seen this talked about before but can not seem to serch/find it. I was looking at my primary fermentor (Day 16) and it seems to have a oily look to the top layer of the beer/wort (whatever its called). Is this normal. I got my tap-a-draft in and was wondering if I should wait some more before racking to tap-a-draft. I am trying not to use a secondary this time, just to see if I can make good beer in primary.
If you're talking about the krausen, yes it's normal. It can look like all kinds of things, like bubbles, mats, or pancake mix. If it's been 16 days take a hydrometer reading and see if it's done. It probably is.
Secondaries aren't necessary for making good beer. It's best use is if you need to clear your primary for another batch to get started (recommended) or it's something that needs to age a long time, say for a few months.
There is a very fine line between "hobby" and "mental illness."
I too have this oily layer in several of my brews. But surprisingly not all of them. And I not not very sure what is causing them. Yes, it could be the krausen, but it looks oily even without the bubbles.
I have seen this on beers when I am racking them into the primary before. I think I have only seen it twice and was concerned at first, but after the beer fermented fine and tasted great I sort of quite caring.
I've seen it too and was wondering if if could be from the hops (been using whole or plugs).
The krausen fell to the bottom at about day 7. Have you ever put gas in a boat and spilled some in the water? It makes the water look all crazy. Looks like that but not to that extream.


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LONDON, UK - JAN. 23: Niall Horan From One Direction Play the Apollo in London on the January 23, 2012 in London, UK
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Liberty Defined: 50 Essential Issues That Affect Our Freedomby Ron Paul
Synopses & Reviews
Publisher Comments:
In Liberty Defined, congressman and #1 New York Times bestselling author Ron Paul returns with his most provocative, comprehensive, and compelling arguments for personal freedom to date. The term "Liberty" is so commonly used in our country that it has become a mere cliché. But do we know what it means? What it promises? How it factors into our daily lives? And most importantly, can we recognize tyranny when it is sold to us disguised as a form of liberty? Dr. Paul writes that to believe in liberty is not to believe in any particular social and economic outcome. It is to trust in the spontaneous order that emerges when the state does not intervene in human volition and human cooperation. It permits people to work out their problems for themselves, build lives for themselves, take risks and accept responsibility for the results, and make their own decisions. It is the seed of America. This is a comprehensive guide to Dr. Paul's position on fifty of the most important issues of our times, from Abortion to Zionism. Accessible, easy to digest, and fearless in its discussion of controversial topics, LIBERTY DEFINED sheds new light on a word that is losing its shape.
"In his latest book, the long-time Texas Congressman and Republican presidential candidate puts his distinctive libertarian spin on some of the most controversial topics in American politics. He sees the primary battle as a struggle to throw off a creeping authoritarianism, characterized by unchecked government spending, foreign military incursions, and other excesses, in order to recapture the original liberties that the Founding Fathers proscribed. Eliminating tyranny from contemporary politics can only be achieved by embracing liberty and not by relying on failed government programs and misunderstood protections, according to Paul. To accomplish that goal, the tyrannical excesses of both Democrats and Republicans must be reined in. In alphabetical order, Paul tackles an eclectic mix of topics from abortion and campaign finance reform to terrorism and Zionism; the unifying construct being that these weighty issues are 'controversial' and 'tend to confuse people.' He is an equal opportunity critic who doesn't hesitate to underline contradictions emanating from both parties. Groupings by topic would have made more sense, but it's a small quibble for anyone determined to understand how Ron Paul views America. "
Publishers Weekly Copyright PWxyz, LLC. All rights reserved.
About the Author
Dr. Ron Paul is a physician and twelve-term congressman from Texas who ran for president in 2008. He is the chairman of the domestic monetary policy subcommittee, and the author of eight books, including the New York Times bestsellers The Revolution: A Manifesto and End The Fed. An advocate of sound money, personal liberty, free markets, and international peace, he is chairman of the FREE Foundation, founder of the Campaign for Liberty, and distinguished counselor to the Ludwig von Mises Institute. He and Carol, his wife of fifty-three years, have five children, eighteen grandchildren, and three great-grandchildren.
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Project Manager - Risk Data Quality
Data Quality Project Manager( Investment Banking / Data ) currently required on a Contract basis for a London based Investment Bank working across Risk. The successful candidate will be responsible for: * Defining and delivering data quality/contr…
- Date Posted:
- 21 Jan 2013
- Job Type:
- Contract/Temp
- Salary:
- £600 - £750 p/day
- Location:
- City of London, East London, North London, North West London, South East London, South West London, West End, West London, London
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text:
Steve Jobs Questioned In iTunes Monopoly Suit 370
from the I've-seen-this-episode-already dept.
We've improved Slashdot's video section; now you can view our video interviews, product close-ups and site visits with all the usual Slashdot options to comment, share, etc. No more walled garden! It's a work in progress -- we hope you'll check it out (Learn more about the recent updates).
How will you expect the editors to took the time to conjugated verbs properly, when there's flamebait to will have been posted?
Ad revenues, man! Slashdot needed / needs / will need / will have needed / had needed / is needing / to need them!
No, of course not. Slashdotters have no trouble understanding sarcasm.
There's no future in time travel.


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After reading this important transcript of a conference to which I was not invited, about media coverage of Ariel Sharon's hospitalization, I wish to address some of the important public and moral questions raised by this affair0 comments
- Haaretz.com
- הארץ
- TheMarker
- עכבר העיר
- TheMarker Café
Hillary Clinton: Return special US-Israel relationship to constructive footing (Haaretz)
25 people hospitalized after Air Canada plane skids off Halifax runway after hard landing (AP)
France's Sarkozy wins local elections, far-right National Front strengthens presence (Reuters)
Authorities: Body found in rubble three days after apparent gas explosion in Manhattan (AP)
Liberia calls for sexual abstinence to cut Ebola transmission risk (Reuters)
Boko Haram attack polling stations, advance on northern city as Nigerians vote (AP)
Tanzania president warns of rising religious tensions before referendum (Reuters)
Former HP CEO Fiorina: Chances of presidential bid 'higher than 90 pct' (Reuters)
Ran Reznick
After reading this important transcript of a conference to which I was not invited, about media coverage of Ariel Sharon's hospitalization, I wish to address some of the important public and moral questions raised by this affair0 comments
How did it happen that the ministry concealed from the public a closure order it had issued for one of the most popular hot springs resorts in Israel?0 comments
In recent months the State Comptroller, police investigations and investigative journalists have uncovered very grave information in an extremely sensitive medical realm: clinical trials on human subjects. The findings include long-term shortcomings by the Health Ministry in the supervision of the hundreds of experiments that are conducted at the hospitals and involve thousands of people every year.0 comments
Could such a campaign that urges the public to ask if the doctor has washed his hands be held in Israel? It's hard to believe.0 comments
Until now, the Health Ministry has failed in most instances in which it is supposed to represent the good of the public and has backed off in deference to the interests of the hospital managements.0 comments
It appears that the ombudsman's unit of the Health Ministry hurries to adopt accounts - that of the physician or of a medical institution - which are prima facie unreasonable without exploring the depths of the circumstances.0 comments
After the State Prosecutor's Office announced in August 2003 that it would not be serving criminal indictments against Prof. Zion Ben Rafael in the matter of the human ova, but instead would file a disciplinary complaint, Prof. Yossi Lessing, chairman of the Israeli Association of Obstetricians and Gynecologists, wrote to him to express disgust with the slander against Ben Rafael.0 comments
In 1987, when Prof. Alexander Aviram was appointed director of Assouta Medical Center, a private hospital in Tel Aviv, he was surprised to discover that, according to arrangements that existed in the institution, physicians who were not on the Assouta staff received payments for referring patients for examinations and treatments at the hospital.0 comments
The State Attorney's Office - despite the seriousness of the medical affairs that have been investigated in recent years - has failed to set up a special department, and no prosecutor has been charged with specializing in the subject, as has been done with economic and security issues.0 comments
The decisions made by the cabinet - transferring NIS 100 million to cover some of the deficit, subject to organizational and structural changes - may have temporarily solved the crisis, but they have not taken even a single step toward a solution of the basic problems of the health system.0 comments
If it's up to Health Minister Danny Naveh, Israelis will soon be able to sell organs for transplant and women will be able to sell their ova (eggs) in return for compensatory payment from the state. However, in the view of many senior figures in the health system, Naveh's move is dangerous and is liable to further worsen the condition of medicine, and indeed of the society in general, in Israel.0 comments
A special seven-justice Supreme Court panel recently upheld the appeal of the family of a victim of medical negligence. In the revised ruling, most of the justices supported the position of Justice Dorit Beinisch, who found in favor of the family's arguments.0 comments
The Health Ministry's ongoing failure to fulfill its legal and public obligations must be called by its proper name: governmental anarchy. The ministry's senior officials, who are supposed to serve the public and act in the public's name, too often forget the public and serve the physicians' guild, instead.0 comments
One of the people most prominently mentioned last week in the Finance Ministry's annual report on wages in the public sector was heart surgeon Prof. Azai Appelbaum.0 comments
All of Israel's health ministers and all the director-generals of the Health Ministry to date have failed in carrying out ongoing supervision and control over the country's health institutions, despite the trenchant criticism leveled on the subject by the State Comptroller, the courts and the commissions of inquiry appointed by the Health Ministry itself.0 comments
Some two weeks ago, the Health Ministry's legal adviser, attorney Mira Huebner-Harel, announced that the ministry wished to initiate an amendment to the law that would prevent the disclosure of findings from inquiries into negligence, oversights and irregular medical occurences.0 comments
In the first study of its kind, which examined the opinions of doctors for the Society for Patients' Rights in Israel, it was found that 40 percent of the doctors reported experiencing pressure from the HMOs not to prescribe costly treatments or tests even if they are included in the national health basket.0 comments
The surrogate parenthood law makes it possible for a woman who cannot conceive or tolerate a pregnancy to have a child in a rented womb. This is one of the most sensitive and troubling laws that exists in the sphere of ordering the relations between people.with Ruth Sinai 0 comments
People who want to know which surgical ward and which surgeon have the lowest mortality rate, where the danger of infection is lowestand the like have no way of getting answers.0 comments
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text:
Bangladesh disaster: Can US brands repair their reputations?
Global clothing brands scramble to protect their reputations after the Bangladesh disaster: Some promise to make amends, while others lie about their connection to the factory whose collapse killed over 600 people.
David Goldman / AP
MUMBAI, India
Global clothing brands involved in Bangladesh's troubled garment industry responded in starkly different ways to the building collapse that killed more than 600 people. Some quickly acknowledged their links to the tragedy and promised compensation. Others denied they authorized work at factories in the building even when their labels were found in the rubble.
The first approach seems to deserve plaudits for honesty and compassion. The second seems calculated to minimize damage to a brand by maximizing distance from the disaster. Communications professionals say both are public relations strategies and neither may be enough to protect companies from the stain of doing business in Bangladesh.
Such experts say that with several deadly disasters and fires in Bangladesh's $20 billion garment industry in the past six months, possibly the only way retailers and clothing brands can protect their reputations is to visibly and genuinely work to overhaul safety in Bangladesh's garment factories. A factory fire killed 112 workers in November and a January blaze killed seven.
"Just public relations is not going to do it," said Caroline Sapriel, managing director of CS&A, a firm that specializes in reputation management in crisis situations.
Over the past decade, major players in the fashion industry have flocked to Bangladesh, where a minimum wage of about $38 a month has helped boost profits in a global business worth $1 trillion a year. Clothing and textiles are 80 percent of Bangladesh's exports and employ several million people.
Yet the country's worker safety record has become so notorious that the reputational risks of doing business there may have become too great even for retailers and brands that didn't work with factories in the collapsed Rana Plaza building or the Tazreen Fashions factory that burned late last year.
Page 1 of 4


text:
Namco Bandai has announced a new Ridge Racer title, Ridge Racer Unbounded.
and made by the "Flatout" poeple.your car is a high-octane wrecking ball.'
'Ridge Racer Unbounded has a new mantra – Drive, Destroy, Dominate – and it's one that's going to shake up the racing genre for good'
Battlefield Hardline Review
27th March 2015
Cities: Skylines Review
20th March 2015
Hotline Miami 2: Wrong Number Review
10th March 2015


text:
Hi everyone! My name is Sara, and I write urban fantasy and paranormal novels as SM Reine. I collect swords, cat hair, and typewriters (which I do use for writing!). I can usually be found working on my treadmill desk at midnight while my four black cats glare disapprovingly.
If you would like to know the instant my next book is available, you should enlist in my Army of Evil! We have a wicked cool secret handshake, but you'll have to sign up to learn it. ;)
Read the free short story, Deadly Hearts, on my website now!
What's new?
Ashes and Arsenic – Book 6 of Preternatural Affairs
Amazon Kindle – Apple iBooks Store – Barnes & Noble – Kobo Books
Agent Cèsar Hawke is in his element when he's investigating magical crime. And with his boss out of town, Cèsar gets to pick which cases he works on. He's bent on doing nothing involving demons, zombies, or fallen angels this time. Instead, he's going to find the witch who used magic to rob a bank.
Easy stuff. Cèsar plans to catch the perp before his boss gets home.
But when he digs into the robbery, he finds much more than missing money. He also finds a deadly turf battle between two covens and a trail of bloody violence.
A trail that leads directly to his brother, Domingo Hawke.
Domingo wants Cèsar's help taking down his enemies. Forget that Cèsar works for the Office of Preternatural Affairs, forget allegiances, forget pesky "contracts" and "conduct." Domingo is calling in a favor and the Hawke family is too tight to refuse.
Blood is the most powerful ingredient in any witch's spell, after all…
What's next?
Omega – Book 1 of War of the Alphas
Preorder on Amazon, Barnes & Noble, Apple iBooks, Kobo Books
Ten years ago, Deirdre Tombs died. When she was reborn the next day, Deirdre had become a shapeshifter who can't shift shapes. Nobody knows what animal she's supposed to be. She's definitely not a werewolf. The Alpha, Rylie Gresham, can't force her to transform like other members of her pack.
Now Deirdre is considered an omega, the weakest shapeshifter in the pack—a vulnerable position when Everton Stark demands tribute from Rylie. He wants to be the dominant Alpha. The only Alpha. And he plans to make her pack submit whether they want to or not. Stark can make every shapeshifter obey him by force of will alone.
Every shapeshifter except Deirdre.
The shifter who can't shift is the only hope for Rylie to win the war against Stark. It will take everything Deirdre has to survive undercover in his den. But can an omega's will be stronger than that of a charismatic, deadly Alpha like Everton Stark?


text:
"Good start..."
It starts out well but has a weak finish. Provide listener with food for thought and gives Americans plenty of reason to prepare.
"Must listen..."
While the information in slow at first it is well worth the listen. This should be required reading in public schools,it would produce a well informed population and stop politicians for talking so much crap.
"Great to have series continue..."
This is good if you have read the other books and a nice introduction to the syndicate worlds.It also provides a nice perspective on the short comings of centralize government.
"Good start"
This was a good way to start a series I will listen to the whole series. the concept is great!
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text:
March 18, 2012; Sacramento, CA, USA; Minnesota Timberwolves point guard Luke Ridnour (13) battles for the ball between Sacramento Kings guard Marcus Thornton (23) and point guard Isaiah Thomas (22) during the first quarter at Power Balance Pavilion. Kelley L Cox-US PRESSWIRE
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Beautiful dark wood queen size bedroom set. Includes headboard, nightstand and dresser. Only a year old. Moving out of state need to sell!
Mar 28 -
Myrtle Beach :
Myrtle Beach - Everything else
Hand Crafted Mahogany Wood Doll Bed Antique Solid Mahogany Poster bed / Frame
Purchased at an Estate Auction some time ago. Small enough for your favorite baby doll or also large enough to accommodate a small - medium dog.A standard size pillow has been used in photos to ...
Feb 23 -
Knoxville :
Sevierville - Baby & kid stuff
Sheffield Stages Crib with free mattress. Like new, only used for granddaughter on occasion. Fixed rail, back rail can be used as headboard later on if desired. Color -Espresso. This crib is in excellent condition and made by Stork Craft Mfg. Bumpers and original assembly ...
Feb 12 -
Charlotte :
Marshville - Baby & kid stuff
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text: This is a gem of a place and worth the walk out of Tinajo. We visited on the first night of our holiday and really enjoyed our meal- my husband had pasta with truffles which was delicious and creamy, while I enjoyed baked camembert. Marco, our waiter, was so friendly and brought over a map to help... read more