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Dynamics and Function of a CA1 Model of the
Hippocampus during Theta and Ripples
Vassilis Cutsuridis?and Michael Hasselmo
Center for Memory and Brain, Boston University, Boston, MA, USA
Abstract. The hippocampus is known to be involved in spatial learning
in rats. Spatial learning involves the encoding and replay of temporally
sequenced spatial information. Temporally sequenced spatial memories
are encoded and replayed by the firing rate and phase of pyramidal cells
and inhibitory interneurons with respect to ongoing network oscillations
(theta and ripples). Understanding how the different hippocampal neu-
ronal classes interact during these encoding and replay processes is of
great importance. A computational model of the CA1 microcircuit [3],
[4], [5] that uses biophysical representations of the major cell types, in-
cluding pyramidal cells and four types of inhibitory interneurons is ex-
tended to address: (1) How are the encoding and replay (forward and
reverse) of behavioural place sequences controlled in the CA1 microcir-
cuit during theta and ripples? and (2) What roles do the various types
of inhibitory interneurons play in these processes?
Keywords: Computational model, microcircuit, inhibitory interneurons,
STDP, calcium, theta, ripples, medial septum, CA1.
Spatial memories in the hippocampus are encoded (stored) and replayed by the
firing frequency and spike timing of pyramidal cells and inhibitory interneurons
during network oscillations. Theta oscillations (4-10 Hz) are observed in rats
during exploration and rapid eye movement (REM) sleep, whereas sharp wave-
associated ripples (100-200 Hz) are observed during immobility, slow-wave sleep
(SWS) and consummatory behaviours. During exploration hippocampal place
cells have been shown to systematically shift their firing phase with respect to
theta as the animal transverses the place field (a phenomenon known as phase
precession) [19].
Many theories have been proposed over the years trying to understand how
memories in the hippocampus are encoded and replayed during network oscil-
lations [7],[15]. Buzsaki's two-stage memory model [15] hypothesized that both
theta and sharp-wave (ripple) states of the hippocampus are essential to mem-
ory trace encoding and replay. During theta (exploratory behavior) neocortical
?Corresponding author.
K. Diamantaras, W. Duch, L.S. Iliadis (Eds.): ICANN 2010, Part I, LNCS 6352, pp. 230–240, 2010.
c ? Springer-Verlag Berlin Heidelberg 2010
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Dynamics and Function of a CA1 Model231
Fig.1. (A) Pyramidal cell model with calcium detectors in distal and proximal den-
drites. (B) Entorhinal cortical (EC) and Schaffer collateral (CA3) inputs during theta
rhythm. (C) Forward replay of CA3 spatial memories used as inputs to CA1 during
ripple activity (location A in figure 2). (D) Reverse replay of CA3 spatial memories
used as inputs to CA1 during ripple activity (location B in figure 2).
information is transmitted to the hippocampus via the dentate gyrus, where it is
encoded by pyramidal cells via synaptic plasticity mechanisms. During the sharp-
wave associated ripple state the pyramidal cells initiate population bursts, which
then cause the already stored memories in the hippocampus to reach the neocor-
tex and hence to be replayed. Hasselmo's and colleagues' oscillatory model [7]
hypothesized that hippocampal theta rhythm (4-7 Hz) can contribute to mem-
ory formation by separating encoding (storage) and retrieval of memories into
independent functional sub-cycles. Recent experimental evidence has shown that
in the CA1 area of the hippocampus the same set of excitatory and inhibitory
cells, which fire at specific phases during theta, are active at completely different
phases during ripples [10], [11], [12]. Similarly, medial septal GABAergic neurons
differentially phase their activities with respect to theta and ripple [14], [17].
Here we investigate, via computer simulations, the biophysical mechanisms by
which encoding and replay of behaviourally relevant spatial memory sequences
are achieved by the CA1 microcircuitry. A model of the CA1 microcircuit [3], [4],
[5], [6] is extended that uses simplified biophysical representations of the major
cell types, including pyramidal cells (PCs) and four types of inhibitory interneu-
rons: basket cells (BCs), axo-axonic cells (AACs), bistratified cells (BSCs) and
oriens lacunosum-moleculare (OLM) cells. Inputs to the network come from the
entorhinal cortex (EC), the CA3 Schaffer collaterals and medial septum (MS).
Our model addresses three important issues: (1) How is the mechanism of phase
precession of place cells in the CA1 microcircuit achieved in presence of various
types of inhibitory interneurons? (2) How are the encoding and replay (forward
and reverse) of behavioural place sequences controlled in the CA1 microcircuit
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232 V. Cutsuridis and M. Hasselmo
during theta and ripples? and (3) What roles do the various types of inhibitory
interneurons play in these processes?
2 Model Architecture and Properties
The CA1 network model consisted of 4 pyramidal cells and four types of in-
hibitory interneurons: two basket cells, an axoaxonic cell, a bistratified cell and
an oriens lacunosum-moleculare (OLM) cell. Hodgkin-Huxley mathematical for-
malism was used to describe the ionic and synaptic mechanisms of all cells. All
simulations were performed using XPPAUT [20] running on a PC under win-
dows XP. The biophysical properties of each cell were adapted from cell types
reported in the literature [5], [9].
Pyramidal Cells. Each pyramidal cell consisted of 4 compartments: an axon,
a soma, a proximal dendrite and a distal dendrite. Active properties included a
fast Na+current, a delayed rectifier K+current, an LVA L-type Ca2+current,
an A-type K+current, and a calcium activated mAHP K+current. No recurrent
connections between pyramidal cells in the network were assumed.
from the CA3 Schaffer collaterals and entorhinal cortex (EC), respectively, and
axon, proximal dendrite and distal dendrite, respectively.
A mechanism for spike timing dependent plasticity (STDP) in each dendrite
was used to measure plasticity effects. The mechanism had a modular structure
consisting of three biochemical detectors, which responded to the instantaneous
calcium level and its time course in the dendrite [1]. The detection system con-
sisted of: (1) a potentiation (P) detector which detected calcium levels above
a high-threshold (e.g. 4µM) and triggered LTP, (2) a depression (D) detector
which detected calcium levels exceeding a low threshold level (e.g. 0.6µM), re-
mained above it for a minimum time period and triggered LTD, and (3) a veto
(V) detector which detected levels exceeding a mid-level threshold (e.g. 2µM)
and triggered a veto to the D response. Calcium entered the neuron through:
(1) voltage-gated calcium channels (VGCCs), and (2) NMDA channels located
at each dendrite. Calcium influx from neither channels alone elicited plasticity.
Plasticity resulted only from the synergistic action of the two calcium sources
(NMDA and VGCC). A graphical schematic of the model pyramidal cell and its
calcium detectors for STDP is shown in Figure 1A.
Inhibitory Interneurons. All inhibitory interneurons consisted of a single
compartment (soma). Active properties of BC, AAC and BSC included a fast
Na+, a delayed rectifier K+and a type-A K+currents [5]. Active properties
of the OLM cell included a fast Na+current, a delayed rectifier K+current, a
persistent Na+current and an h-current [9]. During theta, axoaxonic and basket
cells received excitatory inputs from the EC perforant path and the CA3 Schaffer
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Dynamics and Function of a CA1 Model233
Fig.2. Virtual linear track paradigm used. The rat must transverse the track starting
from location A and stopping at location B. Gray filled ellipses represent the place
fields (PF) of three pyramidal cells (PCs) in the network. Note their fields are non-
overlapping. As the rat transverses the PF, each PC shifts its firing to earlier phases
of the theta rhythm. At locations A and B the rats retrieve either the track locations
to be transversed or the track locations already transversed, respectively.
collateral, inhibition from the medial septum, and recurrent excitation from the
pyramidal cells. Basket cells recurrently inhibited each other and received addi-
tional inhibition from the bistratified cells. Bistratified cells were excited by the
CA3 Schaffer collateral input only, inhibited by the medial septum, synaptically
excited by PC recurrent excitation and synaptically inhibited by the basket cell.
OLM cells received recurrent excitation from the PCs and forward inhibition
from the medial septum. During ripples, the AAC, BC and BSC were excited
only by the CA3 Schaffer collaterals and inhibited by the MS cells (see MODEL
INPUTS subsection for details). The OLM cell was excited by the PCs and
inhibited by the MS cells (see MODEL INPUTS subsection for details).
Model Inputs. Excitatory inputs (spikes) to network cells originated from the
entorhinal cortex (EC) and CA3 Schaffer collaterals, whereas external inhibitory
one from the medial septum (MS). During theta, the EC and CA3 inputs were
continuously present, but at different frequencies (see Figure 1B). The interspike
interval of the EC input was set to 10ms (100Hz), whereas the ISI of the CA3
input was set to 20ms (50Hz) [22]. Both EC and CA3 inputs arrived at the same
time in the CA1-PC dendrites. The MS inputs were modelled as burst cells,
which fired at specific phases of the theta rhythm. One MS burst cell fired at the
peak of the extracellular theta (type 1) [14], whereas the other one at its trough
(type 2) [17]. MS cells inhibited only the network inhibitory interneurons.
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234 V. Cutsuridis and M. Hasselmo
During ripples, the CA1 PCs received forward or reversed excitatory rippled
input only from the CA3 Schaffer collaterals (see Figure 1C and 1D) [15], [21].
The inhibitory inputs from the MS cells were of two types: (1) a cell with a theta-
like oscillation during the ripple-centered epoch, pausing its activity before the
ripple peak and increasing its firing right after the ripple peak (type 1) [17], and
(2) a cell that paused its activity during the ripple episode (type 2) [17].
3 Results
3.1Virtual Linear Track
Our virtual linear track consisted of a rat running from station A to station B
(see Figure 2). In stations A and B the rat was allowed to stand still awaiting
for the GO signal to transverse the linear track. The linear track consisted of
four non-overlapping place field representations of equal dimensions (≈ 25cm).
The virtual rat took 2.25 sec (9 theta cycles) to tranverse through one place
field. Figure 4 shows the firing activities of two place cells (PC 1 and PC4) and
all inhibitory interneurons in two place fields (PF1 and PF4 in Figure 2). Each
place field was encoded by the firing of a single pyramidal cell, whose phase of
firing shifted with respect to the external theta rhythm [19]. As the rat entered
a place field (first theta cycle) of a given pyramidal cell, the first spikes occured
close to the trough of the theta cycle. As the rat was approaching the end of the
field (last theta cycle), they occured near the peak of the cycle, having precessed
almost 180 degrees over the course of 9 theta cycles (see figure 4) [23]. This was
accomplished by the constantly increasing strength of the proximal synapses
due to the STDP learning rule, which increased the tendency of PCs to fire
at earlier theta phases in the presence of a constant level inhibitory threshold
(BSC inhibition) (simulation result not shown). Once the rat reached station B,
it was rewarded and allowed to be engaged into consummatory behaviours. At
the stations A and B, our hippocampal simulation entered a different state of
waking without theta rhythmic oscillations, where sharp wave associated ripple
activity dominated the input and output of CA1 [16], [18]. As experimental
studies have shown at station A the rat experienced forward replay of neural
activity coding the track locations to be transversed [16], whereas at station B
the rat experienced reverse replay of neural activity coding the track locations
it has just tranversed [18].
3.2 Encoding of Spatiotemporal Memories during Theta
Figure 3 depicts the encoding process of spatiotemporal memories during theta.
During theta, input from EC enters the distal dendrite of the CA1 PC cells,
whereas input from CA3 Schaffer collaterals enters the proximal dendrite of
the PC cells. On their own, the EC inputs generate dendritic spikes in the distal
dendrites, which get attenuated on their way to the soma (see figure 3A) [2]. The
CA3 inputs generate excitatory postsynaptic potentials (EPSPs), which fail to
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Dynamics and Function of a CA1 Model235
Fig.3. Schematic of encoding of spatiotemporal memories during the theta rhythm
(see text for details)
Fig.4. (Left) Firing activities of pyramidal cell 1 and all inhibitory interneurons with
respect to theta rhythm. (Right) Firing activities of pyramidal cell 4 and all inhibitory
interneurons with respect to theta rhythm. Vertical arrows indicate phase precession
of pyramidal cell firings in every theta cycle. Nine theta cycles comprise a pyramidal
cell's (place cell's) place field.
generate somatic action potentials, because they are presynaptically inhibited by
GABAB(see figure 3B) [8]. The presynaptic GABABinhibition in CA1 cyclically
changed its strength with respect to theta (active during the first half of theta,
inactive during the second half) [8]. During the first half of theta, the strength
of CA3 input to PC proximal dendrites was reduced by 50%. When the EC and
CA3 inputs were concident in the proximal dendrites of the PCs, then action
potentials are generated in the PC somas (figure 3C).
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236V. Cutsuridis and M. Hasselmo
Figure 3D-F depicts which cells are active during theta. Figure 4 depicts the
firing activities of all network cells during theta. During the first half-cycle of
theta (0-180 degrees), we propose the following: the coincident EC and CA3
inputs cause first the AAC to fire action potentials with interspike interval (ISI)
equal to 20ms, which inhibit the PCs at their axons and prevent them from firing
APs (Figure 3D) [11]. Once the AAC stops firing, BCs, which are modeled as
slow integrators [11], start to fire due to the coincident EC and CA3 inputs to
their somas. Because of their mutual recurrent inhibition, each BC fires every
40ms as in [11]. The role of BCs is to inhibit the PCs and prevent them from
firing, pace subthreshold theta oscillations in PCs [13] and prevent the BSC from
ruining learning in the PC proximal dendrite by inhibiting it (Figure 3E). BSC,
along with the OLM cell, is also inhibited by the type 2 MS cell (Figure 3E).
The type 2 MS cell also inhibits the type 1 MS cell, which in turn disinhibits the
AAC and BCs and allows them to fire and carry-on with their inhibitory duties
(Figure 3E).
Figure 3F depicts the second sub-cycle of theta, which begins as the presynap-
tic GABABinhibition to CA3 Schaffer collateral input to PC synapses declines
and type 1 MS cell approach maximum activity. Because of this septal input,
the basket and axoaxonic cells are now inhibited, releasing pyramidal cells, bis-
tratified cells and OLM cells from inhibition. Pyramidal cells may now fire more
easily, thus, allowing previously learned memories to be recalled. Type 1 MS cell
also inhibits the type 2 MS cell, which in turn disinhibits the BSC and OLM
cell. To ensure the correct place memory of the sequence is recalled, the disin-
hibited BSC broadcasts to all PCs a non-specific inhibitory signal, which allows
the PCs that learned the place memory to recall it, while quenching all other
spurious places memories (e.g. subsequent memories in the sequence). The OLM
cell, which gets activated by the PCs, in turn send an inhibitory signal to the
distal PC dendrite, which prevents the EC input from interfering with the recall
of the pattern.
3.3 Forward and Backward Replay of Memories during Ripple
Figure 5 depicts the replay processes during a ripple episode. In contrast to theta
(figure 4), during the ripple episode (forward or reverse) the firing patterns of
inhibitory interneurons in the network change (figure 6) [11], [12]. During ripple
activity what was locally learned during theta oscillations, it is now retrieved
by the subiculum, entorhinal cortex and the neocortex, where it reached con-
sciousness [15]. The synaptic weights of the proximal dendrite are now fixed (no
changing). Forward and reverse replay activity arise from the highly synchronous
activity of the CA3 PCs [15], [21]. This highly synchronous activity excites first
the AAC, which is disinhibited by the type 1 MS cell (as we mentioned before
the type 1 MS cell pauses its activity for about 25ms before the peak of the
ripple episode and increases it right after it), and in turn inhibit the axons of all
CA1 PCs in the network. The duration of this axonal inhibition is short (less than
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Dynamics and Function of a CA1 Model237
Fig.5. Schematic of the forward and backward replay processes of spatiotemporal
memories during ripple activity (see text for details). Vertical dashed gray line indicates
the peak of the ripple episode.
Fig.6. Firing activities of all network cells with respect to ripples during both forward
and reverse replay of spatiotemporal memories. Dashed yellow line indicates peak am-
plitude of ripple episode. Axoaxonic, basket, bistratified and OLM cells fire the same
way during both forward and reverse replay of memories [11], [12]. During forward re-
play, pyramidal cells fire in a specific order: black, blue, red, and green. During reverse
replay the order is reversed: green, red, blue, and black.
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238V. Cutsuridis and M. Hasselmo
25 ms), since the AAC pauses its firing right after the peak of ripple episode due
to increased activity of the type 1 MS cell. The role of the AAC is to silence the
CA1 network and prepare it for the appropriate retrieval of information based
on the current context. Similar firing activity has the OLM cell in the network,
because it is also (dis)inhibited by a type 1 MS cell. The role of the OLM cell is
to prevent the EC input from interfering with the recall of the memory.
Next, BCs and BSC, which were inhibited by the type 2 MS cells during the
start of the ripple episode are now disinhibited by them and become active from
the highly synchronous CA3 input. The role of the BSC is to provide a non-
specific inhibition to all PCs, allowing this way only the "appropriate" PCs that
learned the pattern(s) to recall it(them). The role of the BCs is to maintain the
highly syncronous ripple activity of the PCs. A similar role is played by the gap
channels in the PC axons [24].
4 Conclusion
A reduced version of a previously published CA1 microcircuit model [3], [4],
[5], [6] is extended to simulate how spatiotemporal patterns are encoded and re-
trieved in the CA1 area of the hippocampus during theta and ripples. Our model
demonstrates: (1) How is phase precession of place cells in CA1 achieved in the
presence of various types of inhibitory interneurons? and (2) How are encoding
and replay (forward and reverse) of behavioural sequences of spatial memories
controlled in CA1 during theta and ripples in the presence of various types of
inhibitory interneurons. Much more work is needed to further explore why the
model place cells don't precess beyond 180 degrees with respect to theta. Does
a full 360 degrees phase precession result from the interactions of a larger and
noiser network of cells or is it driven by phase precessed CA3 inputs? How does
a larger number of simulated theta cycles contribute to phase precession? Also,
what happens to network dynamics and its ability to learn when the presenta-
tion frequencies of inputs change? Finally, what role does dopamine in CA1 play
in binding together temporally sequenced spatial memories?
Acknowledgement. This work was funded by NSF Science of Learning Center
CELEST grant SMA 0835976, NIMH R01 MH61492, NIMH R01 MH60013 and
NIMH Silvio Conte Center grant P50 MH71702.
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text:
Sweeney Todd London | English National Opera
John Owen-Jones as Pilleri, Bryn Terfel as Sweeney Todd and Philip Quast as Judge Turpin
Sweeney Todd London | English National Opera
John Owen-Jones as Pilleri, Bryn Terfel as Sweeney Todd and Philip Quast as Judge Turpin
Sweeney Todd - 2014 Lincoln Center
Featuring: Bryn Terfel, Emma Thompson, Philip Quast, Audra McDonald, Christian Borle, Kyle Brenn, and Erin Mackey
I was fully expecting another stiff concert version of an amazing Sondheim score. Watch to find yourself pleasantly surprised! It's the perfect interpretation for this musical.
EDIT: Original video removed by youtube. Here's a fuzzier version I found. Keep an eye on PBS for a rerun of the full performance!
Inspector Javert
those who follow the path of the righteous shall have their reward
Not mine, taken from Twitter user @rebeccadavid01 but I just had to share on Tumblr. (Not sure if she is on here)
Just WOW!!
10th Anniversary Concert - curtain call
requested by anon.
My most rewound moments (1 of ??)
Since I've been listening/watching some Les Mis lately, I'll start this off with this minute of audio from the 1988 Symphonic Recording of Les Miserables. This is in Paris, right after Valjean has been recognized, and Javert bursts onto the scene. Reason 1 for the (literally) hundreds of rewinds: Philip Quast IS Javert. It;s hard to match him in this part. His voice is the one I always associate with Javert. Reason 2: That guitar. You know the one. During "Could it be he's some old Jailbird…" that electric guitar comes in and it just sounds so EPIC. Gah, I just listen to it over, and over, and over. After I edited this clip, I listened to it 5 times in Audacity. Also, I love the way Quast emphasizes "maggots" and bites into "hunted".
Les Misérables - Tenth Anniversary Concert
listen as philip quast completely out sings the rest of the cast and makes them sound like backing singers in the end bit where they all sing their different parts
they are not "stories," he insists to Valjean; they are merely descriptions of police-work, told for the sole purpose of impressing upon Cosette the futility of crime; he had scarcely even noted that the child seems to find them amusing.
"Hello Little Girl" from the 1993 Sydney production of Into the Woods, with Sharon Millerchip as Little Red and Philip Quast as the wolf.
What I would give to have been able to see this production
Marius preening himself for Cosette.
With Javert smiling in the background like he's giving out his beautiful daughter…
A few people have requested the full version of "Javert's Intervention" and so here it is folks. Now you can all hear Quast snarl "Everyone about your business, clear this garbage off the street!" Pure Gold as well. I also Left in Eponine's "Run for it, it's Javeeeeeeeeeert!" just because I like that part.
Ugh, are you exhausted from people arguing about the Into The Woods movie they haven't seen yet based on a paraphrase of an article that mentioned some out of context, off-hand comments Sondheim made? I sure am.
So let's detox with this hour-long documentary from 1990 focusing on Sondheim's time as a visiting professor at Oxford and the Nation Theatre's production of Sunday in the Park with George.
valjean just doesn't understand
she sees one kiss and BAM she grows up to be a prostitute
Les Misérables 10th Anniversary Concert - Curtain Call

subset: commoncrawl


text:
With an array of applications required to run the average home theater, Grant Clauser writes of his wish for a master app to control all of them. The Harmony Link comes closest, according to Clauser, although it needs an external infrared transmitter to operate, he notes.
View Full Article in:ElectronicHouse.com
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March 30, 2015
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U.S. President Barack Obama is welcomed by Cambodia's Prime Minister Hun Sen as he arrives at the Peace Palace in Phnom Penh, Cambodia, Monday, Nov. 19, 2012. Obama will attend the East Asia Summit.
U.S. President Barack Obama, center, stands with Cambodia's Prime Minister Hun Sen, right, and Vietnam's Prime Minister Nguyen Tan Dung during a family photo session of the East Asia Summit at the Peace Palace in Phnom Penh, Cambodia, Monday, Nov. 19, 2012.
U.S. President Barack Obama, left, is greeted by Cambodia's Prime Minister Hun Sen before the ASEAN-U.S. leaders meeting in Phnom Penh, Cambodia, Monday, Nov. 19, 2012.
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Season of Festivals never takes a break here in India; one after another, each festival brings lot of things. Sweet memories of the last year, new bondings and new relationships; it's time to cherish the old and celebrate the new. And what new things come to you only add cheer and excitement to your life. People love to buy something new during festivals - whether it's Diwali, Raksha Bandhan, Navratri, Christmas or New Year. Of late, Indians have found passion for technology, gadgets and electronics. Mobile phones rule the roost when it comes to shopping.
Sensing this new trend, Infibeam - one of the fast growing e-commerce portals in India - has come up with exclusive mobile offers for Indian consumers. This showcase of mobile phones boasts latest smartphones from leading national and international brands of mobiles at the most affordable prices. Some of the bigwigs of mobiles are Apple, Asus, Blackberry, Gionee, HTC, iBall, Karbonn, Lenovo, LG, Micromax, Microsoft, Motorola, Nokia, Samsung, Sony, Xolo, and more.
While you are here to buy a smartphone, also take a look at the smart mobile accessories. Enhance the performance of your smartphone with screen guards, mobile covers, handsfree, Bluetooth speakers, mobile chargers, MicroSD cards and more. Infibeam has carved a niche in the burgeoning mobile market in India by providing excellent customer services, which include on-the-dot delivery, cash on delivery, easy EMI options and more.
Avail maximum benefits of mobile phone offers floated by Infibeam. Our mobile offer may run for limited period. Hurry, buy now and live a smart life!


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Purebred Himalayan kittens for Sale - 12 weeks old
Purebred, CFA-registered Himalayan kittens for sale early Summer. We have several cats expecting kittens and they should be ready to leave for their new homes in late June. There will be a selection of colors. They come with their first 2 sets of shots and a generous health ...
Mar 25 -
Gorgeous Blue Eye Doll Faced White Persian Kittens
We will have Gorgeous Blue Eye White Persians and Chinchilla Silver Persians, beautiful doll faces, and teddy bear look, wonderful temperament, loves to be cuddled and loved. Health Guaranteed. In the spring, sign up for a beautiful Angelical Persian today. Real lap babies ...
Mar 25 -
6 month old female sphynx for trade
i would like to trade for a different blood line . she is a marbled grey and very sweet. no papers not a breeder
Mar 22 -
Blue Eye White Persian Kittens
We have avail., Odd Eye White Persian boy ready. Top Quality. Health Guaranteed. Very sweet babies, raised with family. Loves to play with everyone. Has Regional Winning bloodlines. Awesome Personalities. CFA registered. Raised underfoot for Great Personalities & Health. On ...
Mar 19 -
Blue Russian mixed with solid white kittens available soon
Dad is a blue Russian. Mom is a solid white long haired. Kittens are expected to be born within the next 2weeks-end of the month. They will go to their new homes at 8 weeks. They will be dewormed and have 1st shots before leaving for their new homes. Expecting 3-4 kittens. ...
Mar 4 -
Gorgeous Blue Eye White Persians
Gorgeous., Blue Eye White Persians & Green Eye Chinchilla Silvers. Awesome Personalities! Real lap babies-wonderful personalities. Top Quality. Health Guaranteed. Soft- velvety coats, long and flowing. Very sweet babies, raised with our family. Have Regional Winning ...
Mar 2 -
Hypo Allergenic Kitty Siberian
Pet lover only, serious inquires
Stunning beauty , playful, smart female 8 month old Siberian cat.
Need to be spayed by future owner
Preferable no small children (age 1-9) in the house on constant base
Loves people and wants to be the center of attention
Has all shots, no ...
Feb 19 -
Cute, lovable, playful kittens
FREE to good home-They need good homes ASAP
Feb 10 -
Beautiful White Persian kittens
We have a gorgeous blue eye white Persian girl kitten avail.for Christmas, beautiful doll faced, and wonderful temperament, loves to be cuddled and loved. In the spring, sign up for a beautiful Angelical Persian today. Real lap babies-wonderful personalities. Babies are ...
Feb 7 -
We currently have one little bengal kitten that need to find a new home this week!!! He is 2 months old right now. He is really lovely, and always in the midst of children and love being a part of family life, and being with humans:) He is very sweet and raised around ...
Mar 30 -
Pittsburgh :
"BISCOTTI" - a cute little fella. 5 year genetic health guarantee. Parents are DNA tested. Happy Healthy and Looking for a nice home. Raised for a Reason - DONATIONS to AUTISM/ASPERGERS
Biscotti is a very sweet playful little guy who enjoys cuddling with his siblings ...
Mar 30 -
Allentown :
"RAVIOLI" is a delicious little kitty. He looks so light now, but will be a very pretty red/silver color with bicolor on his face. He is ever so sweet and comes with a full health guarantee, shots, etc. A portion of all fees are donated to one of three National ASPERGERS ...
Mar 29 -
Allentown :
I have a female himalayan kitten that will be ready to go to her forever home on 5/2/15. All my parents are disease and parasite free. All kittens are raised with my two young children, so they are very friendly and loveable. Kittens are sold as indoor pets only, and you ...
Mar 29 -
Philadelphia :
Mar 29 -
Central NJ :
Friendly and outgoing, will be 8 weeks Easter. Our Spring kittens were gone in two days last year! Reserve now to avoid disappointment. Lilacs, lynxpoints, seals, flamepoints; all home raised underfoot. Health guaranteed.
Mar 29 -
Frederick :
Female Calico Kitten. Beautiful markings. Good with other animals. Asking $20 obo.
I need to find her a good new home soon.
*She is not spayed and might be preg.
Mar 29 -
Charlotte :
Be sure to watch "Penny's Persians" on Facebook the first weekend of April for the very first photos of our gorgeous Seal Point and TortiePoint Himalayan males and females born to CFA registered "Jude" and "Mia" on March 6th...we will then begin to accept deposits upon them. ...
Mar 29 -
Raleigh :
Very cute Scottish fold kittens for sale! Three blue lilac (females) and one cream color (male) all with blue eyes.
Mom is with folded ears and dad straight eared both vaccinated and tested.
Kittens were born on March 1st and will be ready after April 15th.
Local pickup only.
7 weeks female hymalian flat face available for sell . The first shot done and health paper available . Her parents champion . She is cute and playful , healthy
Mar 29 -
Frederick :
Be sure to visit the Facebook page "Penny's Persians" and keep up with the latest photos and videos of our kittens.
The first pics of a litter of male and female Himalayans born March 6 will be posted the last weekend of March...don't miss them!
Soon to follow will be an ...
Mar 29 -
Washington DC :
Mar 29 -
Central NJ :
We have a sweet litter of chocolate Persian babies. There is 2 males still available. Please go to my website for pics of parents and other information about our babies. www.persian--kittens.com
Born 3/3/15 they will be ready to go to their fur-ever home the last week in ...
Mar 28 -
Philadelphia :
TICA Registered Cattery with Over 25 Years Experience
MINKS, SEPIA MINKS ***BLUE eYED WHITES***SOLIDS
Mar 28 -
Baltimore :
Silver Spring
In time for the week of Easter! This is an adorable litter of silver kittens with one fabulous golden boy! A portion of all adoption fees will be donated to AUTISM/ASPERGER foundations. 5 year genetic health guarantee. Clean as a whistle. Parents are DNA tested.
This ...
Mar 28 -
Allentown :


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Welk home deal could close in May: Repairs planned for later this month
BISMARCK – The State Historical Society's purchase of famed bandleader Lawrence Welk's boyhood home could be completed by the end of May, Director Merl Paaverud said Friday.
Members of the Historical Board voted 6-5 in January to buy the homestead from Welk's two nieces, Evelyn and Edna Schwab, contingent on certain repairs being made beforehand.
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Telephone & Addresses
(1 - 4 from 260
Bob McIntyre
11722 Central Islip NY
Bob McIntyre (Age: 26)
91105 Pasadena CA
Bob McIntyre (Age: 37)
99338 Kennewick WA
Yellow Page contacts
Network Profiles
(1 - 4 from 55
MySpace Profile: bob mcintyre (134015410)
Oxnard, CA
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bob mcintyre - Berks Country - Reading Eagle
Bob McIntyre will compete for the 30th time at Sunday's Lyons Fiddle ... Bob McIntyre competed in the first Lyons Fiddle Festival contest in 1983 ...
BBC - A Sporting Nation - Bob McIntyre …
Bob McIntyre thrilled motorcycle racing spectators wherever he went. He possessed an incredible determination to win, astonishing concentration levels and his racing ...
Bob McIntyre quotes
Bob McIntyre quotes,Bob, McIntyre, author, authors, writer, writers, people, famous people.
McIntyre Twilight
Bob McIntyre Twilight Cross Country Meet. ... Bob McIntyre Twilight Cross Country Meet. History. History for McIntyre Twilight. Year, Results, Videos, News ...
Business Profiles
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LinkedIn: Bob McIntyre - Australia | LinkedIn
View Bob McIntyre's (Australia) professional profile on LinkedIn. LinkedIn is the world's largest business network, helping professionals like Bob McIntyre ...
LinkedIn: Bob McIntyre - Canada | LinkedIn
View Bob McIntyre's (Canada) professional profile on LinkedIn. LinkedIn is the world's largest business network, helping professionals like Bob McIntyre ...
Bob McIntyre | Environment Agency | ZoomInfo.com
View Bob McIntyre's business profile as National Technical Advisor at Environment Agency and see work history, affiliations and more.
Bob M. - MoMo Atlanta (Mobile Monday Atlanta) (Alpharetta, GA) -...
Global Wireless Architect & Investment Executive
Private Homepages
About the Artist
Bob McIntyre & Family ... Jane Public is a self-taught artist. Born in 1973 in Catskill, New York ...
Bob Mcintyre - Realtor.com
Check out the profile for Bob Mcintyre on realtor.com(R). Find out about this Tooele, UT agent's professional experience and view properties listed by this agent ...
(1 - 4 from 54
classmates: Bob Mcintyre
Yale High School, Yale, MI, 1985-1989
classmates: Bob Mcintyre
West Technical High School, Cleveland, OH, 1953-1957
ratemyteachers: Bob McIntyre
Beaver Dam, WI, Beaver Dam High School
classmates: Bob Mcintyre
North Andover High School, North Andover, MA, 1988-1992
Celebrities & Politicians
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Wikipedia: Bob McIntyre
Robert MacGregor McIntyre (28 November 1928 Scotstoun, Glasgow - 15 August 1962) was a Scottish motorcycle racer famous for five motorcycle Grand Prix wins which included three wins at the Isle of Man TT Races, and four victories in the North West 200. McIntyre died nine days after injuries sustained racing at Oulton Park, Cheshire in August 1962.
Murray Walker Stars Of Speed - Bob McIntyre - Discogs
Stars Of Speed - Bob McIntyre · Images · Artist · Label · Edit · Log In · Help · Murray Walker And Sharpe, Norman - Stars Of Speed - Bob McIntyre. more images ...
Bad news
(1 - 4 from 23
findagrave: McIntyre, Bob
05/9/1917 - 01/16/1989, Enid (Garfield County, Oklahoma)
Robert "Bob" McIntyre - Legacy.com
It is with great sadness that we announce the passing of Bob McIntyre, on Saturday, August 30 in Victoria, B.C. with his family by his side.
John Robert "Bob" McIntyre - Your Life Moments
Bob McIntyre of RR#1 Clear Creek in his 67th year. Beloved husband of Linda ( nee Armstrong) whom he married April 12, 1969. Loving father ...
findagrave: McIntyre, Bob
11/2/1928 - 08/6/1962, Glasgow (Glasgow City)
Books & Literature
(1 - 4 from 9
Bob McIntyre: The Flying Scot - Mick Walker - Google Books
... Bob McIntyre's memory lives on. An annual Bob McIntyre Memorial race meeting held at East Fortune attracts racing enthusiasts from as far afield as Australia.
Bob McIntyre by Mick Walker (9781859835005)
Bob McIntyre by Mick Walker. Click here for the lowest price! Hardcover, 9781859835005, 1859835007
Bob McIntyre by Mick Walker (9781859839560) - buy book online at...
Bob McIntyre, by Mick Walker (9781859839560) - buy it online at Boomerang Books.
Bob Mcintyre - AbeBooks
Field & Stream The Complete Hunter by Doug Painter, Philip Bourjaily, W. Tarrant, Thomas McIntyre, Bob Robb, J. B. Robinson and a great selection of similar...
Related Documents
3rd Annual Bob McIntyre Twilight Meet.pdf - mstca
3 rd. Annual Bob McIntyre Twilight. Cross Country Invitational Meet. Sponsored by: Dennis Yarmouth Regional High School. Hosted by: Mass State Track ...
Bob McIntyre Twilight Cross Country Meet by patrickbendzick : 2011...
Part of our Bob McIntyre Twilight Cross Country Meet coverage. Bob McIntyre Twilight Cross Country Meet by patrickbendzick. Photos > This Album > 2011 MSTCA Twilight
1954 AJS 497cc E95 'Porcupine' Racing Motorcycle Frame no. F3 ...
29.07.2011 Bob McIntyre, Derek Farrant and Rod Coleman were the riders, the latter providing the Porcupine with its best international results of the season, placing 2nd in Ulster and winning the Swedish Grand Prix. Other riders to swing a leg ...
Video & Audio
(1 - 4 from 30
Bob McIntyre Classic - East Fortune - Brief Clip - YouTube
Brief selection of clips from East Fortune - Bob McIntyre Classic Meeting
Bob McIntyre Biography on Vimeo
► 5:24► 5:24Mini biography I did for The Pinellas Education Foundation's Hall of Honor program. Shot on Panasonic AF ...
Motorcycle Grand Prix - British Pathé
The 250 cc and 500 cc races from the Ulster Motorcycle Grand Prix.
McIntyre Matchless G50 running on Spannerland dyno - YouTube
Bob McIntyre chassis with Minnovation Racing Matchless G50 motor. Taking it for a spin on its first run through the gears on our shop dyno. We weren't lookin...
(1 - 4 from 47
Google News: Un giro di pista in onore di McIntyre
25.02.2012 [GPone] - Subito dopo verrà osservato un minuto di silenzio per il 17enne nativo di Sydney che portava un cognome celebre: Bob McIntyre fu infatti quarto nel mondiale della 500 nel 1961 con la Norton e vinse il TT nel 1957, ma non si segnalano parentele.
Romney's Tax Plan: Progressive, but Only by Republican Standards
23.02.2012 [New York Times (blog)] - Bob McIntyre of Citizens for Tax Justice estimated to the Washington Post that the plan would raise the deficit by $10 trillion. The reason Mr. Romney can claim it would be neutral is evident in the final section of his plan, which would demand
Google News: Obama Strangely Silent on Overseas Tax Rate
22.02.2012 [RollingStone.com (blog)] - "The corporate tax reform 'framework' released by the Obama administration today fails to raise revenue that could be used to make public investments in America's economy and America's future," said Bob McIntyre, who heads Citizens for Tax Justice.
Guardian: US politics live: White House and Mitt Romney compete on tax reform plans
22.02.2012 [The Guardian (blog)] - 2.15pm: For further analysis of Mitt Romney's new tax cuts, the Washington Post's Greg Sargent talks to Bob McIntyre, president of Citizens for Tax Justice, who describes the outcome as a huge tax cut for the rich and a total tax cut of $10tn over 10
Reports & Statements
(1 - 4 from 181
Twitter Posts: Patricia Taylor (pitzys)
2012.07.18 Bob McIntyre | CTV Barrie http://t.co/23mu4UP2
Wikipedia: Bob McIntyre - Wikipedia, the free …
Bob McIntyre may refer to: Bob McIntyre (motorcycle racer) (1928–1962), Scottish motorcycle racer Bob McIntyre (soccer) (1904–1998), Scottish-American soccer ...
Wikipedia: Bob McIntyre (motorcycle racer) - …
Robert MacGregor McIntyre (28 November 1928 - 15 August 1962) was a Scottish motorcycle racer famous for five motorcycle Grand Prix wins which included three wins …
Coach Interview: Quaker Valley's Bob McIntyre - WPXI.com
►►Coach Interview: Quaker Valley's Bob McIntyre. ... Sponsored By: Coach Interview: Quaker Valley's Bob ...
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Bob McIntyre - Motorcycling Icons Poll
Bob McIntyre (1928-1962) Robert McGregor McIntyre was a Scottish motorcycle racer who won three Isle of Man TT races and registered five ...
Bob McIntyre - Sportscotland
Bob McIntyre. (1928-1962). It was the 50th Anniversary of the TT and the year in which the eight lap 1957 Golden Jubilee Senior race was to prove historic in ...
Search Results for "Bob McIntyre" - Portland Business Journal
Portland Search Results from Portland Business Journal
Bob McIntyre : Duke Video
The extraordinary skills of motorcycle racing legend Bob McIntyre can be enjoyed again thanks to Downloads and DVDs from DukeVideo.com. 'Bob...
Bob McIntyre Memorial Bikes East Fortune 16th-17th June ...
Bob McIntyre Memorial Bikes East Fortune 16th-17th June 2 people like this. At March 31, 2014 0 Comments ...
Bob McIntyre The Flying Scot
... Biographies and Rider Profile Books /; Bob McIntyre Biography and Rider Profile /; Bob McIntyre The Flying Scot. Picture of Bob McIntyre The Flying Scot ...
Bob McIntyre Twilight Cross-Country Invitational Meet
WPI Distance runner Ryan Moran put together these great race video's from the 2013 Bob McIntyre Twilight Invitational. Pembroke and McNulty ...
Bob McIntyre Victoria BC - 411.ca Person Search
We found 4 result(s) for Bob McIntyre Victoria BC. ... We found the following people matching bob mcintyre victoria bc. 4 results for ...
Bob McIntyre on Tax Deal, Kevin McKinney on Corporate ...
CounterSpin January 4 2013 Bob McIntyre on tax deal and Kevin ... We'll talk to Bob McIntyre from Citizens for Tax Justice about that. corpfm ...
Bob McIntyre | Pennsylvania AFL-CIO
Make A Donation · Join Working America · Contact Your Legislator · Volunteer. You are here: Home › Entries tagged with "Bob McIntyre" ...
Gifts for Bikers - Bob McIntyre clocks
Bob McIntyre became the first rider to lap the Isle of Man course at 100mph. In the 1957 Senior TT his second lap was at an average speed of 101.03mph.
Honorary title in the air for Bob McIntyre | Barrie Examiner
(STAFF) -- It's only fitting that Bob McIntyre, who talks regularly about the skies, would be appointed the first honorary air colonel of the Air ...
Lois And Bob Mcintyre O | lifenews.ca
Lois and Bob McIntyre Open House Saturday, June 8, 2013 2:00 pm - 4:00 pm Bracebridge Senior Centre. Best Wishes Only! Open House ...
News ARRIS' BOB STANZIONE, CISCO'S BOB MCINTYRE ...
'Original' RRHS coach Bob McIntyre resigns - Rio Rancho Observer:...
Nobody knew it at the time, but Rio Rancho High School varsity girls basketball coach Bob McIntyre's last game at the helm was on March 12.
Bob McIntyre - Competitors - The official Isle of Man TT ...
The excitement generated when hard-riding Scotsman Bob McIntyre, on his 500cc four cylinder Gilera, recorded a speed of 101.03 mph was immense. He won ...
Bob McIntyre - databaseBasketball.com
Bob McIntyre. Robert McIntyre (Bob, Bobby) Position: F Height: 6' 6'' Weight: 215. Born: 1/23/1944, High School: Holy Cross, in Flushing, NY College: Saint ...
Bob McIntyre Memorial - scottishjacobites.com
Bob McIntyre was one of Scotland's greatest motor cycle racers. He was the first rider to lap the Isle of Man Mountain TT Circuit at over 100 mph ...
CapeCodOnline.com Photo Gallery: Bob McIntyre Twilight ...
The Bob McIntyre Twighlight Invitational Meet. John Andres of Barnstable runs in the middle of the pack. Cape Cod Times/Ron Schloerb.
Bob McIntyre Ouija Board - Art Bell
Here is one more I thought of to show more of the paranormal side of his topics. Figured it would be a good one being that Art loves the Ouija ...
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Calgary, Alberta, Canada (March 23, 2015) – NOVA Chemicals Corporation (NOVA Chemicals) today announced findings from research conducted at the company's Centre for Performance Applications and Centr...
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Star Tracks
Kerr walks the runway at a Qantas airline show in Sydney. Plus: Brad Pitt, Liam Hemsworth, Beyoncé and more
Credit: FameFlynet
Published: Tuesday Apr 16, 2013 | 07:00 PM EDT
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DEFINITION of 'Modified Dietz Method'
A method of evaluating a portfolio's return based on a weighted calculation of its cash flow. The Modified Dietz Method takes into account the timing of cash flows, and assumes that there is a constant rate of return over a specified period of time. The Modified Dietz Method is more accurate than the Simple Dietz Method, which assumes that all cash flows come from the middle of the period of time being evaluated.
INVESTOPEDIA EXPLAINS 'Modified Dietz Method'
The Modified Dietz Method is a dollar-weighted analysis of a portfolio's return. It is a more accurate way to measure the return on a portfolio than a simple geometric return method, but can run into problems during periods of heavy volatility or if there are multiple cash flows within a particular period.
Sharpe RatioA ratio developed by Nobel laureate William F. Sharpe to measure ...
Sortino RatioA modification of the Sharpe ratio that differentiates harmful ...
Jensen's MeasureA risk-adjusted performance measure that represents the average ...
PortfolioA grouping of financial assets such as stocks, bonds and cash ...
ReturnThe gain or loss of a security in a particular period. The return ...
Time-Weighted Rate of ReturnA measure of the compound rate of growth in a portfolio. Because ...
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Are These 2015's Most Promising Mutual Funds?For 2015, the mutual funds covered below are likely to offer more upside potential than the vast majority of mutual funds in existence.
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Why These Could Be 2015's 10 Best Mutual FundsThese 10 mutual funds offer strong potential for 2015. Here's why.
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What's Fair Value?Fair value has three different meanings depending on the context.
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I love to travel, especially thru Europe. I am from Argentina but have been living for a long time in the USA. I speak spanish, english, and some italian and german.
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Share apartment with Verena was a very good experience.
Careful, friendly, sympathetic, funny, attentive. It was very nice comment on breakfast or evening of the day planning and details that I was unaware of the city.
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Articles from RotoWire's fantasy archives that mention Trevor Bauer's name.
March 25, 2015
Collette Calls: AL Tout Recap
Jason Collette strategically maneuvered through the AL Tout auction, even receiving a hard-earned stamp of approval for grabbing Brett Cecil.
March 21, 2015
RotoWire Roundtable: March Top 350
RotoWire's group of baseball experts is back with its latest roundtable rankings, in which Nolan Arenado, among others, takes a big jump up the list.
February 28, 2015
Collette Calls: New Pitch Junkie
Jason Collette looks at pitchers who are adding new pitches to their arsenals this year and what difference, if any, it might make. Will Justin Verlander turn things around wtih a new cutter or two-seamer this year?
February 26, 2015
Bats & Balls: Sleepers to Target
Dave Regan names sleepers at each position in his inaugural column of 2015, including Joey Votto whose only question this year is health.
February 25, 2015
Indians Team Preview: Rolling Tribe Gathers Moss
The Indians weren't very busy this offseason, but their big trade was to acquire Brandon Moss from the A's. Darin Brown previews their chances for 2015.
February 14, 2015
RotoWire Roundtable: Valentine's Edition of the Top 350
The first installment of the Roundtable Rankings are up for 2015! Check out the panel's divide on Mookie Betts, among others.
January 30, 2015
Bats & Balls: How to Value Pitching
In his annual magazine column, David Regan lays the groundwork for a quality pitching staff.
September 24, 2014
Bats & Balls: 2015 Breakout Predictions
Nolan Arenado was limited by illness and injury this year, setting himself up for a breakout season in 2015.
Dominate Your Duel: The All-DYD Team
RotoWire's Chris Olson uses the strategic approaches highlighted throughout the season to construct a FanDuel lineup for Wednesday night.
September 23, 2014
Wednesday Lineup Card: Betting the House
Indians left-hander T.J. House hasn't gotten the publicity of Corey Kluber and Carlos Carrasco, but his late-season success has helped the Tribe remain on the edge of the Wild Card race.
MLB Barometer: Blue Bloods
Matt Kemp has caught fire at just the right time for the Dodgers. Will it be enough for them in the playoffs?
September 20, 2014
Pitching Value Meter: Down the Stretch they Come
With a playoff berth in the balance, the Mariners might need 18 innings out of Felix Hernandez this week, which would be just fine for fantasy owners.
September 19, 2014
Painting the Black: The Wild Card Races
Jensen Lewis projects the winners and losers of the Wild Card races over the last 10 days of the season.
House of Shlain: Bound to Leave Boston?
What will the Red Sox do with Mookie Betts this offseason? A crowded outfield and the long-term commitment to Dustin Pedroia could lead to a trade out of Boston this winter, Nick Shlain writes.
September 18, 2014
Friday Lineup Card: Hawkins Hurting More Than Helping
Is it time to cut bait on LaTroy Hawkins?
September 14, 2014
Draftster MLB: Fresh Opportunities and Weekly Picks
Edinson Volquez will face the Cubs and their 84 wRC+ against right-handed pitching Sunday, which makes him an attractive option for those that don't want to spend for Jon Lester or Clayton Kershaw.
September 13, 2014
Sunday Lineup Card: Facing the Giants
Second-tier players on one particular contending team lead postseason runs.
Pitching Value Meter: Strasburg's Quiet Excellence
Stephen Strasburg might have disappointed some this year, but he's still having a fantastic fantasy season.
September 9, 2014
MLB Barometer: All Betts Are On
Mookie Betts is getting an extended run of playing time in September and taking advantage of it. He makes Vlad Sedler's 'Risers' list in this week's Barometer.
September 8, 2014
Tuesday Lineup Card: A Pleasant Odor
Hyped young prospect Rougned Odor is starting to produce at the big-league level.
September 6, 2014
Pitching Value Meter: Two Jokers for the King
Felix Hernandez gets two starts this week against teams he has dominated this year.
September 3, 2014
Thursday Lineup Card: Second Shot For Heaney?
August 30, 2014
Pitching Value Meter: Fightin' Phillie
Cole Hamels has been in a groove since mid-May, and he'll look to continue it in two starts this week.
August 29, 2014
Saturday Lineup Card: Russellin' Some Feathers
Chris Benzine discusses his recommended pickup, the day's transactions, and takes a look at some value picks for Saturday.
August 23, 2014
Pitching Value Meter: Two Starts for Kershaw
A two-start week for Clayton Kershaw comes at the perfect time for fantasy owners, especially for those in head-to-head leagues.
Sunday Lineup Card: Arcia Heats Up Minnesota
Twins' outfielder continues to set torrid pace in August.
August 21, 2014
DraftKings MLB: Weekend Value Picks
RotoWire's Jerry Donabedian takes a look at the top DraftKings value plays for both pitchers and hitters this weekend.
August 18, 2014
Tuesday Lineup Card: Hot Carl
Carl Crawford's been playing every day and producing solid speed numbers for the Dodgers, but remains widely available.
August 16, 2014
Pitching Value Meter: No Taming this Tiger
Max Scherzer is one of the few things going right for the Tigers these days, as he's dominated in his recent starts.
August 12, 2014
Wednesday Lineup Card: Pining For Pineda
Michael Pineda, out since late April due to a suspension and then a back injury, is finally set to make his return to the mound Wednesday.
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September 25,2012
Bright-at-Night Workout Gear for Fall
Is it just me, or did autumn get here really quickly? One day we're burning calories on the beach, and the next we're donning sweatshirts for chilly morning walks. And now...
KEYWORDS fall fitness , Outdoor Cardio , Outdoor Exercise , outdoor sports , outdoors


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Bethel and Los Cabos airports and terminals
Airports in Bethel AK, US
Bethel Airport (BET)
Distance from City Center: 2.4 miles
Akiak Airport (AKI)
Distance from City Center: 26.7 miles
Spb (KKI)
Distance from City Center: 15.4 miles
Kwethluk Airport (KWT)
Distance from City Center: 26.1 miles
Airports in Los Cabos , MX
Los Cabos Airport (SJD)
Distance from City Center: 9.3 miles
Earn up to 5% on hotels and 1% on flights - It's free!
By clicking, I agree to the terms and conditions.
Highlighted price = Cheapest round-trip flights
Prices are round trip per person (conditions apply)
Featured Los Cabos Airport Hotels
El Encanto Inn Hotel Spa and Suites
Calle Morelos #133, San Jose del Cabo Map
FREE Wi-Fi Internet Access and Parking
...After exploring local attractions like Estero San Jose and Playa Del Sol Los Cabos, tourists can head back to El Encanto Inn and unwind in the outdoor pool.... More
Hotel Casa Natalia
Mijares Blvd #4 Map
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...Los Cabos International Airport (7.3 mi/11.8 km)... More
Tropicana Inn
Boulevard Mijares 30 SN Map
...Centrally located in Los Cabos and offering comfortable rooms and suites, Tropicana Inn makes for a suitable starting point for travelers in this side of Mexico.... More
Hotel and Suites Las Palmas
Carretera transpeninsular km 31 Colonia Magisterial Map
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Hotel El Ganzo
Boulevard Tiburon SN Map
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...Creativity and elegance in unique luxury Los Cabos hotel.... More
Flights to Los Cabos
Bethel Airport Information
Just three miles from downtown Bethel is the Bethel Airport. Only four airlines fly in and out of this airport: Alaska Airlines, Yute Air, Grant Aviation, and Era Alaska. If you think that the airport cannot handle your flights, you should think again, because you can easily find flights from Bethel to other destinations in Alaska. You can use Orbitz.com to find low-cost tickets to anywhere one of these airlines flies. Orbitz.com can help anyone who lives in one of the 50 nearby cities that this airport serves.
Parking in Bethel
The Bethel Airport offers parking, although you won't find any special amenities like underground parking garages here. The airport does have plans to build additional parking lots and expand the size of its current lot in the future.
Taking a Cab
If you cannot or do not want to drive to the airport, you need to hire a taxi. There are seven cab companies servicing Bethel, including City Cab, Airport Cab, and Bethel Alaska Cab Incorporated. To ensure that you get a ride when you need one, contact the company several days before your flight. You also have the option of taking a bus to the airport, which should cost around $2.
No Restaurants On-Site
Like many small airports, the Bethel Airport does not have any restaurants on-site. There are several restaurants near the airport, and a few restaurants that you pass along the way, like Final Approach Cafe, Diane's Cafe, and Yolanda's Grill. When you make your travel arrangements through Orbitz.com, you will have more than enough money left over to treat yourself to breakfast, lunch, or dinner before your flight. Although Orbitz.com doesn't offer traditional sales on tickets, it does offer a number of discounts on flights from Bethel.
Los Cabos
Airports in Los Cabos
With warm weather and dozens of different tourist attractions, Los Cabos is a popular spot for travelers. If you need help finding a low fare or cheap flights to Los Cabos, you can get help from Orbitz.com. The website searches through the top hotels and flights, giving you access to the best prices. Los Cabos International Airport is the largest airport serving the area, and it is one of the largest airports in Mexico. The airport has four terminals, and you will find that most major airlines operate out of the hub, including American Airlines, Delta Airlines, United Airlines, and Virgin America. It's less than 20 minutes from major attractions and hotels.
Transportation Around Los Cabos
While some people enjoy walking around Los Cabos, the best way to see the city is in a vehicle. Orbitz.com provides deals on rental cars that you can pick up from the airport. Many of the top hotels also provide free shuttles for guests, which you can you to get to the airport at the end of your stay. Taxis are also available, and you should expect to pay between $10 and $20, depending on the distance.
Los Cabos Weather
Los Cabos has a subtropical climate, which means that the area has moderately warm weather throughout the year. Wear sunscreen and lightweight clothing during the warmer months, as temperatures can reach the high 90s. Even during the winter months, the temperatures are still in the 60 to 80 degree range.
Major Attractions in Los Cabos
Beaches like El Estero and La Playita are popular with tourists. Los Cabos also has other attractions and museums, including the Charles Stewart Gallery. Whether you are looking for a vacation with an international flare or you just want to find cheap flights to Los Cabos, you can book all of your travel arrangements through Orbitz.com.
More to explore for Bethel to Los Cabos
Promo Code Terms and Conditions
Book a qualifying 4-night flight + hotel vacation package between January 1, 2014 12:00AM CST and June 30, 2015 11:59PM CST, for $1000 or more for travel between January 1, 2014 and September 30, 2015 via Orbitz and instantly receive $150 off the hotel portion of your booking through the use of the promotion code. Limit one discount per hotel room and one promotion code per booking. Discounts are not redeemable for cash for any reason. Promotion codes cannot be resold. Any attempt at fraud will be prosecuted to the fullest extent of the law. Void where prohibited, taxed or restricted. Orbitz reserves the right to change or limit the promotion in its sole discretion. Promo code not valid for Las Vegas, NV bookings.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 48 hours. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.


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Lady Antebellum's Hillary Scott Welcomes Baby Girl
It's a girl for Hillary Scott of Lady Antebellum.
It's a girl for Hillary Scott of Lady Antebellum.
According to a recent tweet at the official Lady Antebellum Twitter page, Hillary Scott's due date is drawing near -- very near. Despite being nine months pregnant in the heat of summer, the singer is keeping a good attitude, even joking about a prank husband Chris Tyrrell played on her.
Hillary Scott of Lady Antebellum is just waiting for her baby to make an appearance, as are millions of the trio's fans. In the meantime, Scott and her husband are getting plenty of entertainment from Jeff Daniels and musicals.
Lady Antebellum's Hillary Scott is beyond the home stretch of her pregnancy. She is due to welcome her daughter this month, and she is spending the last few days of the gestational period practicing.
The members of Lady Antebellum said they were satisfied with their third album, 'Own the Night.' But looking back, the trio's producer called it an artistic disappointment. That feeling provided more than enough motivation and focus to make sure their latest effort, 'Golden,' was something they could live with forever.
Lady Antebellum and Jake Owen have just been announced as two of the four headliners for Country Jam 2014 in Grand Junction, Colo. After a star-studded lineup left fans hoarse from screaming in 2013, next year's list of artists is shaping up to be even better.
Following Lady Antebellum's Saturday (June 15) performance at the Taste of Country Music Festival, Hillary Scott officially went on maternity leave. The singer is set to deliver her little girl sometime next month. The group's final set was much more than just another show.
On Saturday night (June 15), Lady Antebellum took the stage for the last time before Hillary Scott becomes a mother. The trio stunned the crowd at the first-ever Taste of Country Music Festival, ending the three-day event in a way only they could.
If you couldn't join the thousands of country music fans at Hunter Mountain in New York this weekend for the Taste Of Country Music Festival, well we have good news, you still can check out all of the great performances!
Lady Antebellum nabbed the 2013 CMT Award for Group Video of the Year for their uptempo hit 'Downtown,' a hilarious, goofy clip that saw the band members adopt drastically different personae.


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Plastic Surgery Scar Spotted on Kylie Jenner's Face
Gisele: I Knew Tom Brady Was 'The One' On Our First Date
This 9-Year-Old Model Is Being Called the "Most Beautiful Girl in the World"
The Embarrassing Reason Khloe Kardashian Knew She Needed to Lose Weigh
Selena's Scandalous Selfie Sparks Drama
Watch Miley Cyrus Fall Down on Stage While Wearing a Fake Butt
Watch Miley Cyrus Fall Down on Stage Wearing a Fake Butt
This Star Pretty Much Hates Living Next Door to Taylor Swift
John Travolta Made Everyone Uncomfortable at the Oscars
Perfect Imperfections: Celebs With Unusual Physical Attributes
Guess the Celebrity Sibling
Bruce Jenner Rocks Red Nail Polish, Smokes Cig on His Birthday
Kanye West Just Killed a Kardashian Family Tradition
Kim Kardashian's Hair Hygiene Confession
Iggy Azalea's Latest Confession Will Blow You Away
Halle Berry Can't Keep it Together: The Latest Drama Unveiled
Taylor Swift Stuns Everyone by Posting Sexy Bikini Pic
Mismatched Celebrity Couples That Weirded Us Out
What Does Kylie Jenner Look Like Without Makeup?
32 Ridiculously Cute Queer Women Couples
The ultimate Tesla-killing machine? BMW preparing Model S fighter
Usher Reveals Devastating News About His Son
Inside The Lavish World of 1 Year Old North West
5 Lesbian and Bi YA Titles We're Excited About
How Penny Stocks Are Creating Millionaires Every Day
Is This Drake's Secret Side Chick?
Emma Watson's Intentional "Side Boob"
Anna Wintour's Reaction to North West is The Best Thing Ever
The First Photos of Lily Collins and Chris Evans are Here!
Why We Want The Lesbian Taylor Swift Rumors To Be True


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Black And White Cotton Dress
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Donning this flared dress makes you want to accompany every hello with a few spins. A floral-embroidered mesh bodice overlay and tulle-lined hem bring pep and prettiness to this black-and-white design, which has you exuding carefree charm all evening long!
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PRLog - March 6, 2013 - BEVERLY HILLS, Calif. -- cuador has a significant presence at the 2013 Natural Expo West. The country, known for its outstanding organic fruits, vegetables, seafood and confections has an extraordinary selection of organic and gourmet products to satisfy the most discerning palate.
Visit Ecuador at the 2013 Natural Products Expo in Anaheim
Through the popular and solidarity economy, individual growers and small home-based manufacturers have been able to join together to form dynamic associations which have made it possible for outstanding products to make it to the world marketplace.
Companies selected by Ecuador to participate on behalf of the country in the 2013 Natural Products Expo are:
CHANKUAP: Natural lotions and soaps.
BOROBAR: Energy bar made with Borojo.
PLANTAIN REPUBLIC: Plantain Chips under brand "Tropic Max".
HOJA VERDE: Chocolate & Coffee.
AGROAPOYO: Dried Fruits.
SISACUMA: Beauty oils and concentrates.
Visit by the Ecuadorian Booth (#4366) at the 2013 Natural Expo West on March 7th to 10th, at the Anaheim Convention Center, see the range of products available and place your order! Sponsored by the Trade Commission of Ecuador in Los Angeles, representatives from the Trade Commission and the Associations will be on hand to answer questions and provide materials.
For more, please call Popular Press Media Group (PPMG) +1-310-860-7774, or email firstname.lastname@example.com


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Local Miami Comics Will Record Live Comedy Album During South Beach Comedy Festival
Jason Alexander To Take Over For Larry David In "Fish In The Dark"
Jerrod Carmichael Show Gets a New Name and Will Start Aug 5 along with Craig Robinson Sitcom
What Took So Long!? Willie Nelson Is Launching His Own Brand Of Weed
Yelp Is Freaked Out About The Documentary Being Made About Them
McDonald's Has Finally Figured Out How To Revive Their Business
Monsanto Shill Refuses To Drink Pesticide He Claims Is Safe To Drink
'Girl Crush' Country Song Getting Dropped From Radio Stations For Being Too Gay
Christie's Looking To Make Record Amount Of Money Off One Picasso
Yoga Teacher Performs Oral Sex on 15 Year Old Boy at Arizona Bar Mitzvah
Uh Oh, Kate Upton's Diva Behavior Might Be Hurting Her Career
Finding comedy in everything and everything in comedy.
interrobang, in·ter·ro·bang [in-ter-uh-bang] ‽ (often represented by ?! / !?), is a nonstandard punctuation designed to combine the question mark (?) and the exclamation point (!), indicating a mixture of query and interjection, as after a rhetorical question.
Focusing on the most interesting ! and ? in life, theinterrobang.com is a place to talk about the comedy in everything, and everything in comedy. From street corners to theaters, arenas, print, television, film, or even the White House, if it's funny, or should be, we're talking about it. We also continue to bring you everything happening in the news that's worth discussing, the best recommendations on the internet, and interviews with the most creative people on the planet.
Interested in contributing? Hit us up on our contact page.
We love when you leave comments and we encourage active discussion and debate throughout the site. However our moderators may delete any comments at their discretion, particularly any comments that are off topic.
Of course, defamatory, libelous, threatening, or otherwise illegal posts will be removed as well as any posts that are deemed abusive, or intentionally inflammatory. We also ask that you be respectful of our authors, guests, and other commenters. We reserve the right to edit or delete comments at our discretion. If you have any complaints about a comment being removed, you should contact us using our contact form.
By submitting a comment and/or question to the site you give us the right to use, post, reproduce and distribute your comment as we see fit.
Copyright © Orange Pop Media LLC Thanks to Shout It Out Design


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• Male • $499
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Limited-time feature
29 year old woman | Jacksonville, FL, USA | Seeking men 26-35 within 15 miles
I plan on living forever.. so far, so good.
well.. hello! I have been in Jacksonville for about 4 years now... I teach physically impaired students for a public school here in Jacksonville. I am looking for someone that enjoys some of the same things I do, is kind, honest, trustworthy (that's the most important thing to me), and a Christian. I enjoy doing the same things most people like to do... going out to eat, going to the movies, having a few drinks at a low key pub, go to the beach.. whatever comes up. My job is hard so I certainly don't mind staying home and watching a movie. I like to try new things and I stay active by going to the gym. Health is important to me. I love to cook healthy meals and take cycling classes. So.. just on here to see who else is out there and possibly find a serious relationship. If you want to talk more you can message me! :)
Coffee and conversation , Cooking , Dining out , Hobbies and crafts , Movies/Videos , Music and concerts , Exploring new areas , Nightclubs/Dancing , Performing arts , Religion/Spiritual , Shopping/Antiques , Travel/Sightseeing
Cycling, Other types of exercise, Running, Weights / Machines
I exercise 3-4 times per week.
I have Cats
poes tavern, lynches, shim sham room, green room
University of North Florida, Jacksonville, FL
animals, reading, scary shows/movies, beach
I like to go to the beach, go out with my friends to neptune or st. augustine areas, going to the movies.. whatever comes up really. I'm like to try new things and go to new places.
World War Z
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|What she is looking for
|5'2" (157cms)
|5'10" (177cms) to 6'5" (195cms)
|Body type:
|Athletic and toned
|About average, Athletic and toned
|No preference
|Light brown
|Black, Light brown, Dark brown, Blonde, Dark blonde, Platinum
|No Way
|No Way
|Social Drinker
|Social Drinker
|Education / Teacher / Professor
|No preference
|I'll tell you later
|No preference
|Never Married
|Never Married
|Have kids:
|Wants kids:
|No preference
|White / Caucasian
|White / Caucasian
|Christian / Other
|Christian / Catholic, Christian / Other
I love going to Celebration Church! I go every week.
|English, Spanish
|Bachelors degree
|Some college, Bachelors degree, Graduate degree, PhD / Post Doctoral


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70-Year-Old Florida Woman Attempts To Have Her Daughter-In-Law Killed Recounts Criminal Defense Attorney
Lakeland, FL (Law Firm Newswire) December 4 , 2013 - Jacksonville police arrested a 70-year-old Florida woman after she approached an undercover detective to kill her daughter-in-law.
"This case is decidedly unusual for several reasons. The woman allegedly paid an upfront deposit of $500, with the balance due on the death of the discussed target, handed over the woman's address and picture, met with the supposed 'hitman' for a second time, advanced him another $1,000 and indicated the man could rob the intended victim of her expensive jewellery," outlined Lakeland criminal defense attorney, Thomas Grajek, who is not involved in the case.
The woman soliciting a killer-for-hire, also stated her daughter-in-law's diamonds would bring the man extra money for his trouble. When the undercover officer asked her if she was sure she wanted the job done, the woman allegedly replied that if the 'killer' did not complete the job, that she would do it herself. It was further stated the target was a bad mother and drunk all the time.
Aside from the question of why the woman would want to have her daughter-in-law killed, for allegedly drinking too much, it is obvious that she likely has not only a personality disorder, but may also suffer from some form of mental illness. "These are things that need to be considered in any defense mounted in this woman's favor," indicated Grajek.
On arrest, the elderly woman was taken to jail, read her Miranda rights and charged with two capital felony crimes: criminal conspiracy and criminal solicitation. A capital felony is a crime that may be punishable by execution. The woman immediately requested a criminal defense lawyer. While this may appear to be an open and shut case, there are many underlying factors that could change the course of how this situation unfolds. If, for instance, the woman has a history of mental issues or suffers from delusions of persecution, this needs to be factored into her defense.
"She may well have said that she wanted her daughter-in-law dead, but have no sense of the reality of the situation. She may also not be taking any medications for mental issues, if they have been prescribed," Grajek pointed out. Everyone is entitled to a well thought out defense, no matter what the facts may be.
Thomas C. Grajek
206 Easton Drive, Suite 102
Lakeland, FL 33803
Phone: 863.688.4606
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- Criminal Profiling is not just done on TV
The law enforcement tactic of criminal profiling, pioneered by FBI Agent John Douglas, is not just a tool injected into TV shows for extra entertainment, but is a reality in law enforcement, even used to try and hunt down Jack the Ripper in London. Profiling does not take place in a vacuum and investigators rely on any evidence found at a crime scene to draw conclusions. Other important aspects police consider are the crime location, the circumstances of the crime, whether it is similar in nature to another crime (using the same modus operandi), if there is any physical evidence […]
- Sexually Dangerous Convicts Can be Held Indefinitely
The government now has more power and discretion in holding sexually dangerous convicts. At one time, once a sexually dangerous inmate served a full sentence, he or she was released. The U.S. Supreme Court has now indicated this may no longer be the case when it comes to sexually dangerous convicts. How is a convict classified as being sexually dangerous? There are two conditions that an inmate must meet prior to receiving this classification. In the first, a court must see clear evidence and convincing proof that the convict would not be able to stop molesting children or cease sexually […]
- Arrest made in Polk County "SWAT"ting incident involving "anonymous" calls to police to lure SWAT team to high school.
A Canadian juvenile was arrested in the recent Polk County "swatting" case. "SWATting" is when an individual attempts to lure the SWAT time to respond to a location for a fake threat of some type. Polk County deputies allege the teen anonymously placed hoax calls to law enforcement officials in an effort to lure SWAT teams to respond to Ft. Meade high school over the past four-months. Deputies say the investigation began in September, when an unidentified male called the sheriff's office and Fort Meade High School and said he was going to "drive to Fort Meade High School in […]
See other news sources publishing this article. BETA | Tags: attorney, criminal defense, Florida, law, lawyer, Thomas Grajek


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Worm Casting Warning!!!
I harvested my first batch of worm castings. I started my worm bin in September and this is my first batch. Everything looked good when I dug out the first load of castings but now, a week later, check out the container I put them in.
If I would have used these to immediately add to my garden, I would have had all of these volunteer tomatoes coming up. I am not sure how to eliminate them as I used kitchen scraps to feed my worms and apparently all the seeds went into the bin as well as the tomatoes.
On the plus side, at least we know the castings are nutritious!
Mr jusme newby:
What you harvested wasn't worm castings. It was way less than "finished". The texture of finished VC is much finer.
Oh, it's good for sprouting seeds, but can and will get to be the real deal if you sprinkle a little patience on it.
I have some material a worm once nodded his hat to that I put into a warm room a couple of weeks ago. The intent was to get exactly what happened to your material to happen. It did. I am happy. Think of it as a pre-sprouting party for the vermicompost. I wonder if there is a percentage of the seeds left in our material that did not sprout and will try again later? I made use of this ability when I used the material on bald areas in the lawn. I tossed grass seed on. Then for the next few weeks I could tell just where to avoid mowing due to the pumpkin plants that sprouted. When the grass was strong enough I could mow straight again.
I had a few seeds start in my bins but I never expected to see so many after the worms and the castings were separated. I was hoping to use these in my SFG this spring but I guess I will have to use them only in those squares that I have transplants growing so I can tell the sprouts I need to remove.
Actually, I have another bin of just castings that have a lot more volunteers. Can't wait to harvest the rest of the castings.