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Tuesday, November 12, 2013Perspective: Skeptics & BelieversDave Rat 11/12/13 07:12 PM,Let me clarify perspectives. On one side we have the perspective of believers, the "anything is possible crowd," where the sky is not the limit, and whether a concept is repeatable or provable is not nearly as important as the fact that it was written, thought, or spoken. On the other side we have the perspective of skeptics, the self-proclaimed "investigators of verifiable proof " residing in a world of science, which is based upon identifying dependable and repeatable ideas… View this post
Filed in: Live Sound • Feature • Blog • Opinion • Education • Engineer • Mixer • Sound Reinforcement • System • Technician
Monday, November 11, 2013Win-Win: Handling The Business Part Of The BizCraig Leerman 11/11/13 01:06 PM,While working with gear, hanging out with artists, and getting paid to mix music seems like an easy gig, I've noticed the tendency of some audio folks to forget that this is indeed a business. There's a reason it's called show business, not show play. Recently I was reminded of this fact when speaking with a new client. It seems that her long-time audio supplier didn't return her calls or emails, and so she went shopping for a new vendor.… View this post
Filed in: Live Sound • Feature • Blog • Opinion • Training • Business • Education • Engineer • Sound Reinforcement • Technician
Tuesday, October 29, 2013Sound Reinforcement Or Reproduction? It's All About The IntentKarl Winkler 10/29/13 10:17 AM,One of my first jobs in the pro audio business was to make cables, do simple repairs and be a general "tech" at the USC film school audio department. I was one of those destitute students who asked around about "anything I could get" in terms of work. And this was it. It was a good experience for a number of reasons, foremost of which was that THX guru Tomlinson Holman was one of the main teachers at the film… View this post
Filed in: Live Sound • Feature • Opinion • Poll • Production • Audio • Concert • Engineer • Signal • Sound Reinforcement
Wednesday, October 23, 2013Sonic Nirvana? Thinking Outside Of The "Technically-Oriented" BoxJames Cadwallader 10/23/13 08:15 AM,Whenever I'm at the local Guitar Hut, I like to listen to the people who come in and talk with the pro audio sales guy about gear. These conversations are often filled with nebulous audiophilic adjectives like "warm", "sweet" and "punchy". The sales guy has little motivation to be a source of truthful or accurate information. He just wants to make a sale. Meanwhile many of his customers already have their minds made up as to what piece of gear… View this post
Filed in: Live Sound • Feature • Blog • Opinion • Analog • Business • Engineer • Mixer • Signal • Sound Reinforcement • Technician
Friday, October 11, 2013The Old Soundman: Earplug Wearin' Musicians & An Insolent NewbieOld Soundman 10/11/13 01:53 PM,Dear Old Soundman— Yes, SPA1! Were your parents named SPA.09? I've enjoyed reading your comments for some time now. See, even though you have named yourself after a decadent outdoor love tub, you're okay! I wonder if you might give us your insight regarding musicians who use earplugs (sometimes very sophisticated earplugs,) but then require ridiculous monitor levels on stage. There was a lack of love in these people's lives when they were children. I run into more problems with… View this post
Filed in: Live Sound • Feature • Blog • Opinion • Analog • Education • Engineer • Mixer • Monitoring • Signal • Sound Reinforcement • System
Wednesday, September 11, 2013Remembering Snooks, A Giant Of New Orleans Guitar BluesMark Shemet 09/11/13 01:47 PM,I first saw Snooks play live in the late 1980's at the Rock 'n' Bowl, New Orleans. It was a Monday after the New Orleans Jazz Festival, a double bill with Johnny Adams (the "Tan Canary"). The cover charge was $7. Snooks was set up as a trio, and both bands were separated by the center bar, taking alternating sets without a break, playing on the floor with no risers while people bowled. Snooks played every request and threw in… View this post
Filed in: Live Sound • Recording • Blog • Audio Pundit • Opinion • Sound Reinforcement • Studio
Sunday, August 18, 2013Hands-On Versus By The Book: The Path To Learning How To MixKarl Winkler 08/18/13 03:52 PM,How do we teach aspiring audio professionals to mix? How important is teaching? Can some people even be taught? I've seen debates in the ProSoundWeb LAB forums as to whether mixing sound can/can't be taught. There are a couple of interesting books I've read that relate to this idea. The first one is "This Is Your Brain On Music" by Daniel Levitin. Levitin addresses the age-old question of talent versus work effort, and essentially concludes that the real deciding factor… View this post
Filed in: Live Sound • Feature • Blog • Opinion • Consoles • Engineer • Mixer • Sound Reinforcement • Technician
Friday, August 09, 2013The Difference Between Replaceable And InvaluableM. Erik Matlock 08/09/13 05:11 PM,This article is provided by The Art Of The Soundcheck. During my time with the last AV crew, I watched people come and go. Most who stayed for any length of time fit into one of a few categories: —People who worked cheap. —People who the owner felt obligated to keep. —People who were absolutely invaluable. That's pretty much it. We had our roadies. They set up shows, broke them down, hauled gear, loaded and unloaded trucks, cleaned the… View this post
Filed in: Live Sound • Feature • Blog • Opinion • Business • Engineer • Sound Reinforcement • Technician
Thursday, July 25, 2013Going Deeper: 25 Hz Is The New 50 HzDoug Fowler 07/25/13 11:00 AM,You heard it here first… A couple of years ago at the ULTRA Festival in Miami, I did single-ended measurements of various EDM (electronic dance music) genres using SysTune from AFMG. I merely set the averaging to infinite, put the analyzer in RTA mode, and let it run for hours, sampling internet streams of trance, house, bass music (drum and bass and dubstep), etc. One thing that's clear is that there are two frequency bands that dominate the bass region:… View this post
Filed in: Live Sound • Feature • Blog • Opinion • Loudspeaker • Measurement • Signal • Sound Reinforcement • Subwoofer
Learning The Trade: Going To School Versus Going To WorkM. Erik Matlock 07/25/13 08:05 AM,This article is provided by The Art Of The Soundcheck. I'm a graduate of The Conservatory of Recording Arts and Sciences in Arizona. Loved it. Learned the foundational stuff. After graduation, I made several mistakes. Actually, while I was there I made a lot, too. Took some heat from the old guys about going to school when I got out. Why did I go to school? I started out like a lot of people. Grew up monkeying with gear.… View this post
Filed in: Live Sound • Feature • Blog • Opinion • Business • Education • Engineer • Technician


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Just getting into home brewing. What is the diff. between all grain and partial mash?
all grain is just that, all grain. partial mash is some grain and some LME/DME. Most of the fermentable sugars in a partial mash still come from the LME/DME while all the sugars in all grain come from the grain.
All grain uses more grain in a batch and generally requires a larger kettle to work with. I'm sure some of the AG brewers here can chip in some more differences.
Kegged: Smokier Smoked Porter
Both are about the same amount of time/work, but AG requires some equipment beyond what extract or PM brewing requires: most notably, a kettle large enough to boil 7 gallons or so, a wort chiller to chill it quickly, and a mash tun/alutering system of some sort.
The reason some homebrewers do partial mashes is that there are many grains that don't really contribute anything to an extract beer if just steeped--they need to be mashed with some amount of a base malt like 2-row malt in order for their sugars and flavor contributions to be extracted.
So PM brewing opens up the many more possible grains available to the AG brewer, without some of the expensive equipment required.
BTW, partial-mash is *not* the same thing as extract w/steeping grains. That seems to cause some confusion here sometimes.
partial mash: using some grains to convert starch to sugar and suplimenting with some other sugary supstance be it dme or other.
All grain: using all grain to convert starch to sugar
the temps for the mash should be kept arount the magin zone of 150° to 160°.
you will find on the internet some really simple instructions and some mind numbingly complex instructions but Pauls Page is a great place to start
So a recipe is either all grain or partial mash but it can't be both right?
It might be misleading to describe a recipe that uses 12 lbs of grain and 1 lb of malt extract as a "partial mash", but since it is not ALL grain....
I just call them beer recipes.

subset: commoncrawl


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To finish floors before cabinet installation or after
Currently the new hardwood floors are in but are not sanded and unfinished.
We currently have most everything done waiting for cabinets to arrive which is about three weeks away.
The question is, should we finish the floors prior to having the cabinets installed (since we have time) and covering with protective paper
is it better to have them finished after cabinets installed.
I am leaning towards having them done before as then we could move right along after the cabinets are installed and not have to deal with trying make time for the floor guys and all the associated dust.
I do trust the cabinet guys will take care during install
What would you do
Ours was done like poohpups - sanded, 2 coats, then 3rd coat is after cabs are installed. He had asked us to "disappear" for a night or 2 while the final coat dried. guess we'll be going thru that process again due to repairs to water damage :(
Ours were also like Pooh's. Install, sanded, stained, and two top coats. Then cabs went in the kitchen and DR. (We installed new unfinished wood floors in entry, FR, LR, DR, mudroom, and kitchen as part of a whole house reno.) Very last item before we moved in was the last top coat.
I did cover the floors with Ram board (like thin cardboard on a roll, but water resistant) after the two top coats. The inspector, carpenters installing a house full of trim and doors, electrician, cab maker, wood floor company, painting company doing trim and doors,and plumber were all impressed with the board. All those guys and tools tromping in and out over months did zero damage to the floors.
Like Breezy, I advise something more heavy-duty than rosin paper if you go that route. I put down rosin paper and then sheets of masonite (AKA hardboard). It is less than $10/sheet, and I could cover the exposed area with 3 sheets. The peace of mind was worth the $.
Yes, thanks for the different perspectives.
I've decided to have them finished prior to cabinet install and protect them. I am familiar with the RAM board, it is a great product and I have some so that is what I will use.


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2015 Lenten Schedule
God does not ask of us anything that he himself has not first given us.
Pope Francis 2015
Lent, Holy Week & Easter February 18 ~ April 5, 2015
Meditation Books will be available at the entrances the weekend of February 14/15.
Rice Bowls…Blessing of Rice Bowls during all Masses weekend of February 14/15…learn more here.
Ash Wednesday Schedule – Masses: 6:45am, 12:10pm, 7:00pm
Lenten Daily Mass Schedule
- Mondays: 9:00am
- Tuesdays: 9:00am Communion Service
- Wednesdays: 10:00am Mass
- Thursdays: 6:45am Mass
- Fridays: 6:45am & 9:00am Masses
- Wednesday, March 4
- Religious Ed 1st Wednesday Masses 8:05am & 8:50am
- no 10am Mass on this day
Lenten Mission: – Spiritual Spring Training w/ Fr. David McCallum
February 23-25, 2015 ~ 7:00pm
Using the analogy of physical exercise, St. Ignatius of Loyola, the founder of the Jesuits, describes how the practice of spiritual exercise can bring about personal wholeness and well-being through a deeper relationship with God. Fr. David will facilitate experiences that can help us grow in self-awareness, inner freedom, and that helps us draw closer in our personal relationship with God. The retreat will weave together talks, exercises, and time for questions and conversation.
- February 21/22: Preach all Masses
- February 23: Finding Our Inner Room
- February 24: Finding God in Our Lived Experience
- February 25: Encountering Jesus
Light refreshments will be served each evening.
Annual Lenten Fish Fry – Friday, March 6, 5:00pm-7:00pm
Cazenovia College Hubbard Dining Hall
Haddock, Clam Strips, Mac & Cheese Dinners w/French Fries, Coleslaw, Dessert & Beverages.
All proceeds to benefit Faith Formation & Youth Ministry programs.
Lenten Soup Suppers – Wednesdays in Lent
March 4, 11, 18 5:45pm ~ 6:45pm
Stations of the Cross
- March 4: Marian Stations
- March 11: 6th & 8th Grade Stations
- March 18: In The Words Of Pope Francis
- Stations of the Cross are also located on the East wall of the Daily Chapel for personal reflection. The Daily Chapel is accessible Monday ~ Friday during the day.
Lenten Penance Services – TBA
March 30: Leave The Light On Reconciliation 4:00-7:00p
Adult Faith Formation
Monday evenings ~ 7:00pm March 2, 9, 16, 23
Facilitated by Kyle Reger
Mystery Players – Friday, March 20 ~ 7:30p
Immaculate Heart Central Mystery Players from Watertown present a living Stations of the Cross. Meditation and contemplation on the death and resurrection of Jesus is the central mystery in the prayer life of the Catholic Church.
Lenten Grade Liturgies – Sunday, March 22: 1st & 9th Grade
Holy Week – March 29-April 4, 2015
Palm Sunday, March 28/29
- Saturday Vigil, 5:00pm
- Sunday, 9:00am & 11:00am
- Procession with banners and palms leading into the Church.
Holy Week Daily Masses
- Monday March 30 – Daily Mass: 9:00am
- Tuesday, March 31 – Communion Service: 9:00am
- Wednesday, April 1 – Daily Mass: 10:00a
- Set up Garden in Daily Chapel: 10:30a
Holy Week Services
Holy Thursday, April 2
- Liturgy of the Lord's Supper, 7:00pm
- All Night Adoration in "The Garden," 8:00pm
Good Friday, April 3 – Solemn Commemoration, 12:00pm
Holy Saturday, April 4
- Blessing of Easter Food, 12:00pm
- Easter Vigil, 8:00pm
Easter Sunday, April 5, 2015
- Masses: 9:00am, 11:00am
A Gardener's Prayer
Father of all gardeners, we thank Thee that in the long ago Thou didst begin the world in a garden..
We thank Thee for the morning and the singing of the bird.
We thank Thee for the quiet and peace of eventide and the blessing of sleep which comes with the night.
As we rise in the morning to work in our gardens, grant that the toil of our bodies may bring tranquility to our minds; that the growth of our plantings be exemplified in the growth of our souls; that the fruit of our trees be the perfect attainment, the crowning glory of a life dedicated to Thee. Amen.
From Hidden Hills Garden Website posted by Peggy Hill.


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Woodard Mesh Top Contract Round Bistro Table
30" Size
36" Size
42" Size
48" Size
Special Offer:
24 Issues of Better Homes and Gardens
Included with your purchase - a $10 value (Subscription and Rebate Info)
Woodard Mesh Top Contract Round Bistro Table
Weights & Dimensions
30" Size
36" Size
42" Size
48" Size
|Product Type: Bistro table; Dining table
|Table Shape: Round
|Style: Traditional
|Finish: 1: Black
|Finish: 2: Brown
|Finish: 3: Espresso
|Finish: 4: Green
|Finish: 5: White
|Primary Frame Material: Metal
|Secondary Frame Material: Metal
|Top Material: Metal
|Rust Resistant: Yes
|Seating Capacity: 4
|Commercial Use: Yes
|Country of Manufacture: China
|Umbrella Hole (36", 42", 48" Size): Yes
|Umbrella Hole (30" Size): No
|Assembly Required: No
About the ManufacturerSince 1866 the Woodard name has been upheld by master craftsmen loyal to the unparalleled standards established by founder Lyman Woodard. Beginning in the 1930's, the Woodard family developed the first collection of hand-crafted wrought iron furniture. This innovation marked the birth of casual outdoor furniture and ultimately led to casual furniture designs made from a variety of materials, the most prominent being cast and tubular aluminum.
Throughout the years, Woodard expanded its product offering. Changing lifestyles with an emphasis on comfort prompted Woodard to enter the tubular aluminum market. Soon after, Woodard began manufacturing cast aluminum furniture, providing an assortment of quality crafted casual furniture pieces. Most recently, Woodard added an all seasons wicker line focused on design innovation and comfort.
Today, Woodard continues the tradition of hand-crafted wrought iron furniture with the same quality craftsmanship implemented by its founder. Under the flagship Woodard brand, wrought iron, cast aluminum, tubular aluminum and all seasons wicker products are manufactured using the finest materials available, state of the art finish systems, and quality control systems second to none in our industry.
Woodard Mesh Top Contract Round Bistro Table
Questions & Answers (2)
"Hi, what is the weight for the 36" size table?" asked by Xena
"Hi, what material is this table made of?" asked by Lydia
Still have questions about this product? We're here to help
|5 star
|4 star
|3 star
|2 star
|1 star
Customer Reviews
Attractive table.
Barbara from Columbia, MD – Verified Buyer
I was able to choose a size and color to match other items which are 10 years old and from a different company.The only issue I had was with the delivery process. The table sat in a warehouse 20 minutes away for almost a week. Then I got notification of delivery date and time about 12 hours in advance and never received a 30 minute courtesy call. I requested a delivery receipt and was told that they didn't have one. I opened the garage door so that the box could be placed just inside, as the driveway was wet. Although he eventually deposited the box (upside down) in the entry to the garage, the delivery man objected quite a bit.
Super Deal!
Robert from Oak Forest, IL – Verified Buyer
Got this (48" white) on a clearance sale, included free Motor freight delivery. This table is HEAVY. I expect it will last a good long time. We have a smaller one (same brand) we bought locally almost 20 years ago. It is a bit rusty (underneath), but has been out on our patio for the entire 20 years - rain, snow and all.
Almost What We Wanted
Susan from SEATTLE, WA – Verified Buyer
We'd been wanting a sidewalk-cafe style table for some time, and this came almost as advertised and when they said it would. This table listed does not have an umbrella hole in it--we have no need of one--but the table shipped has one. We shrugged and kept it, since it would have been a huge hassle to return from our condo--we had to break the box down to get it inside, so no way were we going to try to re-box and return. Luckily, it was in good shape, so we just put it out on the patio as is. We are happy with the table. Not sure I'd use Wayfair again, though.
Great bistro table
Cheryl from Fulton, NY – Verified Buyer
This table is very sturdy and a great addition to my patio!
Sturdy & Stylish
David from Washington, DC – Verified Buyer
Good solid table for the money. All welded construction, no assembly required.
Great table!
Emma from CO – Verified Buyer
The table is actually great! It's fine quality and we're pretty happy with it!
Lynn from San Anselmo, CA – Verified Buyer
Bought this 36 table to replace my 12 y.o. 48 Woodard table (still in good condition) that was too big for my smallish deck. Perfect fit and matches my 4 high-back bouncy swivel chairs. Great shipping with NO assembly required. Happy camper!
Perfect fit
Bonnie from Tatum, TX – Verified Buyer
Looks great and fits just right. Just what we needed. Nice and sturdy no assembly required (which I am very grateful for),
Mesh Top Round Bistro Table
Bob Crystal from Austin, Texas
Purchased for outdoor patio use. One piece unit with no assembly required. Excellent build and finish quality with a great price and superior customer service. I'll definitely use Wayfair again.
good buy for the price
adam the runner from Philadelphia, PA – Verified Buyer
Solid build quality, no setup, nice looking product.
OUR SKU # WD1217Mesh Top Contract Round Bistro Table is also sometimes listed under the following manufacturer numbers: 208135 Finish: 86, 208136 Finish: 13, 208136 Finish: 86, 280134 Finish: 13, 280134 Finish: 19, 280134 Finish: 20, 280134 Finish: 21, 280134 Finish: 25, 280134 Finish: 27, 280134 Finish: 35, 280134 Finish: 39, 280134 Finish: 43, 280134 Finish: 45, 280134 Finish: 48, 280134 Finish: 52, 280134 Finish: 62, 280134 Finish: 72, 280134 Finish: 75, 280134 Finish: 83, 280134 Finish: 86, 280134 Finish: 90, 280134 Finish: 92, 280134 Finish: 93, 280135 Finish: 13, 280135 Finish: 19, 280135 Finish: 20, 280135 Finish: 21, 280135 Finish: 25, 280135 Finish: 27, 280135 Finish: 35, 280135 Finish: 39, 280135 Finish: 43, 280135 Finish: 45, 280135 Finish: 48, 280135 Finish: 52, 280135 Finish: 62, 280135 Finish: 72, 280135 Finish: 75, 280135 Finish: 83, 280135 Finish: 90, 280135 Finish: 92, 280135 Finish: 93, 280136 Finish: 19, 280136 Finish: 20, 280136 Finish: 21, 280136 Finish: 25, 280136 Finish: 27, 280136 Finish: 35, 280136 Finish: 39, 280136 Finish: 43, 280136 Finish: 45, 280136 Finish: 48, 280136 Finish: 52, 280136 Finish: 62, 280136 Finish: 72, 280136 Finish: 75, 280136 Finish: 83, 280136 Finish: 90, 280136 Finish: 92, 280136 Finish: 93, 280137 Finish: 19, 280137 Finish: 20, 280137 Finish: 21, 280137 Finish: 25, 280137 Finish: 27, 280137 Finish: 35, 280137 Finish: 39, 280137 Finish: 43, 280137 Finish: 45, 280137 Finish: 48, 280137 Finish: 52, 280137 Finish: 62, 280137 Finish: 72, 280137 Finish: 75, 280137 Finish: 83, 280137 Finish: 86, 280137 Finish: 90, 280137 Finish: 92, 280137 Finish: 93


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Native Plants
Q. Who is Mr. Smarty Plants?
A: There are those who suspect Wildflower Center volunteers are the culpable and capable culprits. Yet, others think staff members play some, albeit small, role. You can torture us with your plant questions, but we will never reveal the Green Guru's secret identity.
Did you know you can access the Native Plant Information Network with your web-enabled smartphone?
Ask Mr. Smarty Plants is a free service provided by the staff and volunteers at the Lady Bird Johnson Wildflower Center.
Need help with plant identification, visit the plant identification page.
rate this answer
Friday - September 03, 2010
From: Liberty Hill, TX
Region: Southwest
Topic: Transplants, Watering, Trees
Title: Mexican Plum not doing well in Liberty Hill, TX.
Answered by: Jimmy Mills
QUESTION:Two summers have passed since I planted my Mexican Plum. It's in full sun. It seems to have added height but not much width. It's virtually a 7 foot stick with 1 foot branches from top to bottom. It always looks a little wilty but in the recent heat some of the leaves on top have turned deep orange. When I do water it I use two five gallon buckets with small holes in the bottom. In these 100 degree days I water every two weeks. Is this tree supposed to look like a skinny shrub? Should I be trimming it up from the bottom?
Mexican Plum Prunus mexicana (Mexican plum) is the common wild plum of the forest-prairie border from Missouri and eastern Kansas to Texas.
From the information available, I'm guessing transplant shock. The plant has not been able to establish a root system that is in balance with the top of the plant. Until it does, the plant won't prosper.
What to do? First of all, don't fertilize. This is often our first impulse, but a stressed plant doesn't need fertilizer. Instead, add some mulch, working it in around the base of the trunk, leaving a thin layer on the top in order to hold moisture and provide nutrients as it decomposes. It can also protect the roots from the excessive heat. The plant needs evenly moist, well drained soil for the roots to develop, so continue your watering regime, slacking off some when the fall rains come.
The appearance of the leaves is normal for Mexican plums at the end of their growing season.
The links below add additional information about transplant shock, as well as tips for preventing it, and correcting it. One of the tips you'll find is to be patient
From the Image Gallery
More Watering Questions
Why did mountain laurel turn brown and die?
July 20, 2011 - I have (had) a lovely mountain laurel that I planted more than 25 years ago. Many times one or two branches would turn brown and I would trim them out. The shrub is about 10 feet tall and is many tr...
view the full question and answer
Problem with Salvia Mystic Spires in Chesterfield VA
May 30, 2009 - Last August, our local Lowes had these beautiful, unusual blue perennials on the discount rack called "Salvia Mystic Spires". For 50 cents each, they looked terrific, so I bought all they had, about...
view the full question and answer
Dry browning leaves on Monterrey Oak from San Antonio
August 08, 2013 - I have a Monterey Oak that was planted four years ago and was doing great until the last two weeks. It has turned brown and the ends of the branches are very dry and brittle. The root flare was cov...
view the full question and answer
Correct cultural conditions for liatris
April 15, 2008 - I recently bought some gayfeather (liatris pycnostachya) and planted in my yard in a nice full sun spot. Gets sun for roughly 10 hours a day. However, it's also the single driest spot in my yard (jus...
view the full question and answer
Leaf fall from Cedar Elm planted in clay
August 17, 2008 - I saw the answer to leaves falling off a cedar elm planted in clay. However I planted a Cedar Elm in my back yard. I dug a hole in the grass then planted and put grass back on top. I water every other...
view the full question and answer
|Support the Wildflower Center by Donating Online or Becoming a Member today.
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Marathon Swimmers Federation
Ted Erikson at Promontory Point, Chicago. Photo by Louise LeBourgeois.
Standards and guidelines for undertaking solo open-water marathon swims in any body of water. Globally endorsed.
MSF Documented Swims have been conducted, documented, and authenticated according to the highest standards of integrity.
Recognizing the most outstanding marathon swims of the year, and the people who contribute most selflessly to the sport.
Regional open water swim calendars, curated by locals.
Current calendars: U.S. (6 miles & up), Southern California, Midwest, Mid-Atlantic.
MSF's Global Blog Feed represents 54 marathon swimming blogs from around the world.
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Stay updated on the latest news, swim successses, and blog posts from the world of marathon swimming. Arrives weekly to bi-weekly.Join our Mailing List
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New York Knicks vs. New Jersey Nets
Episode Reviews (1)
The New York Knicks vs. the New Jersey Nets. These teams meet four times per year, but it is always an exciting battle when they do. The Nets essentially face four road games here during this series, as just by listening to tonight's crowd you could tell there were more Knicks fans in Newark, NJ than Nets fans. The Nets gave a strong effort, but the Knicks just hit too many late shots. Wilson Chandler and Landry Fields refused to miss late and the Knicks were able to pull out the win in a game that the New Jersey Nets desperately needed.moreless


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It is about time that Ali Abdullah Saleh steps down. Saudi Arabia was a large player in why this finally happened. Although he said he will cede power he will likely have a lasting influence in the government. Hopefully the elections will help push Yemen in the right direction. With such a young population, this is the perfect time to change the way things have been going in Yemen in hopes of bettering their future.
the history of Abdullah makes the Yemen people no trust him anymore and no one can blame them about that. but there is a point really take my attention which is the agreement that Abdullah sign with the Saudi's king, may be the people in Yemen don't believe him any more but I think we should look at it from a different prospective. the agreement has said that Abdullah will not be judged nor him or any of his family. and here we should stop and ask a simple question. Is what Abdullah did in his country a crime or not, did he kill his own people or not? in my prospective, yes, and I think a lot of people have the same answer. So, why he is not be judged and why the Saudi kink agree with such agreement? that is totally unfair to see such a man how killed his people and some other power man trying to help him to be out of this situation. Abdullah should be judged and pay for what he did in his country, 33 years as a president and his state goes d=from bad to worse, he just was careful about collecting money and gain power over poor people half of them are jobless and most of them are uneducated. Abdullah should stand in front of these people to be judged and pay for all of this mess. simple this is justice.
Ali Abdullah Saleh has been close to resigning many times before and backed off last minute. At this point, until it doesn't actually happen, people won't be sure and satisfied that he is finally gone. He has power over some things it seems like but really doesn't amount to much if people have been protesting for 9 long months for his resignation and he has been busy trying to recover from the assassination attempt during the summer. From what I can tell, he finally decided to let go off his presidency because of all the international pressure, the pressure from the Yemeni people themselves and the death of Gaddafi. In addition, he will be granted immunity from the US.
Although Ali Abduallah Saleh has stepped down, his influence will most certainly still remain on the new leaders. He set up the new system for failure, leaving it with problems that he put into place and problems that only he could resolve.
The Yemen people's attitude about Ali Abdullah signing agreement to end his 33 year reign over the country was clearly stated as they celebrated with fireworks and gunfire on November 23rd. Also, Abdullah will still hold the title of president but will no longer be making any decisions. His family and himself will also have immunity which prevents him for being accountable for the many deaths that occurred to his opposition. He also continues to dominate the security forces and military forces which have been used in recent times to face his opposition. This is not the first time that he has said that he would resign from power so the Yemen people have the right to be doubtful.
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Australian-based mining and civil contractor MACA credits its strategic entry into South America and increased exposure to gold for its 6.2% increase in after-tax profit to $A34.7M for the six months to Dec 2014 (H1 FY15). Revenue rose 4.4% to $319.7M.
Despite having two contracts close since year end due to falling commodity prices, MACA reaffirms its FY15 net profit should exceed FY14's $55.4M on revenue of about $620M and anticipates a "very strong positive working capital movement".
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The shutdown of Arrium's Southern Iron operations in Australia is the first manifestation of an ongoing company redesign that will see 580 workers laid off with more to come.
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It says Andy Well Stage 2 will be worth $A9M over about six months for openpit mining services including drilling and blasting, loading and hauling, offsetting the financial impact of losing the low-value Paroo project. MACA tips FY2015 revenue over $650M.
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Miner Beadell Resources and contractor MACA have concluded a deal Beadell expects to greatly improve efficiencies and cut costs at its Tucano Gold Mine. By Mark Mentiplay
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University at Buffalo President Satish K. Tripathi has released
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Among the 236,000 University at Buffalo alumni around the world,
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Annie Dorsen, the award-winning performance artist and director
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The University at Buffalo School of Dental Medicine will unveil
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Casey Bunce has a fever and the only prescription is —
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You might expect teenagers to scoff at sitting through a
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This year's Spring Seminar Series at the University at
Buffalo Research Institute on Addictions will focus on the topics
of smoking and alcohol.
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Bisping a 'little pissed off' at Lombard's potential title shot
In a recent interview with MMADieHards, Michael Bisping talked Chael Sonnen, Hector Lombard, Anderson Silva, and more.
Michael Bisping fights Tim Boetsch at UFC 149 on July 21 in Calgary.
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Recent Comments »
5/22/12 8:05 PM by BigEyedFish
lost to Matt Hamil
5/22/12 8:02 PM by phdinmma
5/22/12 7:21 PM by The Governor
War bisping
5/8/12 11:14 PM by Bat21
Reading above, I said "...the term roids as it was used..." referring to Idsmashit's post in which he accused Hendo of cheating because he was on roids, implying that Hendo's use of TRT was illegal.
5/8/12 10:55 PM by Savron
Spitsping deserves everything he gets.....
5/8/12 1:03 PM by sakurabasHeadBeatAronasKnee
That the term roids implies something illegal. Other than that I'm in complete agreement with you
5/8/12 11:35 AM by Bat21
To which false statement are you referring?
5/8/12 11:30 AM by sakurabasHeadBeatAronasKnee
The term steroid is not with reference to anything being illegal, doctors regularly use steroids to help patience with any number of ailments!I don't like or condone roids or trt in Mma, nor do i like false statements
5/7/12 11:02 PM by Bat21
Yes, testosterone is a steroid, you get a gold star. But the term "roids" as it was used implies something illegal, and we all know that's not the case, unless you choose to be obtuse. EDIT: Grammar


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Anyone know how to get paint off hardwood floor
designhelpJune 11, 2011
We have white oak hardwood flooring in our master bedroom. At some point before we moved in, paint was spilled on the floor. I am not able to scrape the paint up or even wash it up. My husband thinks perhaps it is oil paint but we don't know for sure. Has anyone had this problem and figured out how to get the paint up w/o ruining the finish?


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Palazzo Bernardo is a rooftop apartment in the heart of Venice. Palazzo Bernardo, Venice
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Sleeps 4 to 8


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March 11th, 2014
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February 26th, 2014
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February 25th, 2014
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Orchid: This dreamy fragrance is an airy fragrance that is more fantasy than reality. Many orchid varieties do not have a scent but the flower is so beautiful that it deserves an equally breathtaking fragrance. Orchid is a blend of exotic notes (including ylang ylang, rose, jasmine and oriental woods) that come together to form an ethereal nectar that deserves to be in your products.
"Thank you for your prompt response. Bramble Berry has the best customer service of any company I know of. Pass the word!" -Rene
Kevin of Devinely Designed creates beautiful soap and shares his creations via his YouTube channel, Devinely Designed. With over 100 videos, Kevin has made a name for himself in the community for providing creative and educational soap making videos. From a Dandelion Zebra Swirl Tutorial to his first experience making liquid soap, Kevin's videos are fun and […]
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Planting plans: Course details methods to encourage natural landscapes
BEMIDJI — Mary Mitchell purchased her home in March, an attractive two-story house positioned in the middle of a quarter-acre lot in Nymore.
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Breaking Ground: Hartford ballpark Blockbuster tours to fill stadiums More money, tech in preview centers Comcast stakes claim at SunTrust Park Breaking Ground: Orlando City plans Breaking Ground: Daytona technology Kings have lofty goal for new suites Farmers deal served its purpose Chance meeting got Allen on right track Braves hire Van Wagner
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Sidearm Sports adding bigger schools to roster after acquisition by Learfield SportsPublished in SportsBusiness Journal on 03 / 30 / 15
At least 19 colleges, including several from the power five conferences, plan to shift their digital rights to Sidearm Sports, the technology company owned by Learfield Sports. Learfield clients Indiana, Texas A&M and Louisvil...
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Screens to give Jags room for content
The Jacksonville Jaguars' plan to install the NFL's largest video screens at EverBank Field goes much deeper than taking over bragging rights, according to team President Mark Lamping . The club announced June 19 that it will repl ...
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The shape of roofs to come
The inventor of a classic children's toy has assumed a key role designing the retractable roof of the Atlanta Falcons' new stadium, the facility's signature element. Chuck Hoberman, inventor of the Hoberman Sphere, a geodesic dome that breaks down to a fraction of its original s ...
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Daytona to showcase amenities
Daytona International Speedway plans to develop the most sophisticated, premium-seat experience NASCAR has to offer. The track's $400 million renovation project, which begins next week, will introduce big league amenities to the most important track on the NASCAR circuit. It also will bring ...
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Lambeau bleachers create exception
T he NFL has provided some flexibility for the thousands of Green Bay Packers season-ticket holders accustomed to bringing their own seat cushions to Lambeau Field . The NFL's new bag policy, announced by the league earlier this month, l ...
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Rapids team with 2lemetry on data
The Colorado Rapids are using player performance data as an amenity at their new club at Dick's Sporting Goods Park. The Summit Club powered by 2lemetry is named for a Denver developer of cloud-based technology for mobile applications. Last year, 2lemetry signed a five-year deal valued in t ...
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Ballparks host Spartan Race
Fenway Park has hosted numerous non-baseball events during its 101-year history, from an Irish Republican Army meeting to professional wrestling matches and even a John Philip Sousa concert. The ballpark, however, had never been home to a mass-participant obstacle race before this past November, ...
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Twins target midsize concerts
T he Minnesota Twins are using Target Field to test the need for a midsize amphitheater in the Minneapolis-St. Paul market. The Twins, in conjunction with local promoter Sue McClean & Associates and K-TWIN FM , are producing the inaugu ...
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Bank puts name on Singapore venues
The Singapore Sports Hub has a memorandum of understanding in place with OCBC Bank to buy naming rights to three specific venues in the massive $1.5 billion complex. The 15-year deal has a total value stretching into eight figures, and it will rename the Singapore Indoor Stadium, a 24-year-old ar ...
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Kings' design RFP going to select group
T he Sacramento Kings are targeting a small group of sports architects to design their new $448 million arena. AECOM , 360 Architecture , Populous and Rossetti will be issued the request for proposal, industry sources said. Over the past ...
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A tree grows for StubHub activation
StubHub's friendly marketing persona, Ticket Oak, is branching out to the stadium experience in Southern California. Ticket Oak's Backyard, an outdoor space branded after the talking tree that dispenses event tickets to surprised customers in StubHub commercials, is the centerpiece of t ...
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Are you Keiichi Takagaki?Claim your profile
Publications (105)285.4 Total impact
Article: Effects of divalent cations on bovine testicular hyaluronidase catalyzed transglycosylation of chondroitin sulfates[Show abstract] [Hide abstract]
ABSTRACT: Glycosaminoglycans were prepared as salts of different divalent cations and tested as donors in bovine testicular hyaluronidase catalyzed transglycosylation reactions. All of the metal cations examined had similar binding efficiency of divalent cations to hyaluronan. However, cations bound with different efficiencies to chondroitin sulfate species and the differences were marked in the case of chondroitin 6-sulfate; the numbers of cations bound per disaccharide unit were estimated to be 0.075 for Mn, 1.231 for Ba, 0.144 for Zn, and 0.395 for Cu. While barium salt of chondroitin sulfates enhanced transglycosylation, the zinc salt of chondroitin sulfates inhibited transglycosylation. Therefore, by selecting the proper divalent cation salt of chondroitin sulfates as a donor in the transglycosylation reaction it is possible to improve the yields of the products.Biochemical and Biophysical Research Communications 02/2011; 406(2):239-44. DOI:10.1016/j.bbrc.2011.02.024 · 2.28 Impact Factor
Article: Novel proteoglycan glycotechnology: chemoenzymatic synthesis of chondroitin sulfate-containing molecules and its application.[Show abstract] [Hide abstract]
ABSTRACT: Proteoglycans consist of a protein core, with one or more glycosaminoglycan chains (i.e., chondroitin sulfate, dermatan sulfate and heparin sulfate) bound covalently to it. The glycosaminoglycan chains account for many of the functions and properties of proteoglycans. The development of proteoglycan glycotechnology to exploit the functionality of glycosaminoglycan chains is an extremely important aspect of glycobiology. Here we describe an efficient and widely applicable method for chemoenzymatic synthesis of conjugate compounds comprising intact long chondroitin sulfate (ChS) chains. An alkyne containing ChS was prepared by an enzymatic transfer reaction and linked with a chemically synthesized core compound containing an azido group using click chemistry. This method enabled highly efficient introduction of ChS into target materials. Furthermore, the ChS-introduced compounds had marked stability against proteolysis, and the chemically linked ChS chain contributed to the stability of these core compounds. We believe the present method will contribute to the development of proteoglycan glycobiology and technology.Glycoconjugate Journal 08/2009; 27(1):189-98. DOI:10.1007/s10719-009-9252-y · 1.88 Impact Factor
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ABSTRACT: When the products of hyaluronan (HA) digested by bovine testicular hyaluronidase (BTH) were analyzed by high-performance liquid chromatography (HPLC), minor peaks were detected just before the main even-numbered oligosaccharide peaks. The amount of each minor peak was dependent on the reaction conditions for transglycosylation, rather than hydrolysis, by the BTH. Mainly based on HPLC and MS analysis, each minor peak was found to correspond to its oligosaccharide with one N-acetyl group removed from the reducing terminal N-acetylglucosamine. Enzymatic studies showed that the N-deacetylation activity was closely related to reaction temperature, pH, and the concentration of NaCl contained in the buffer, and glycosaminoglycan types and chain lengths of substrates. These findings strongly suggest that the N-deacetylation reaction in minor peaks was due to a novel enzyme contaminant in the BTH, N-deacetylase, that carries out N-deacetylation at the reducing terminal N-acetylglucosamine of oligosaccharides and is dependent on HA hydrolysis by BTH.Glycoconjugate Journal 12/2008; 26(5):559-66. DOI:10.1007/s10719-008-9200-2 · 1.88 Impact Factor
Article: Structural interactions in chondroitin 4-sulfate mediated adherence of Plasmodium falciparum infected erythrocytes in human placenta during pregnancy-associated malaria.[Show abstract] [Hide abstract]
ABSTRACT: Infection with Plasmodium falciparum during pregnancy results in the adherence of infected red blood cells (IRBCs) in placenta, causing pregnancy-associated malaria with severe health complications in mothers and fetuses. The chondroitin 4-sulfate (C4S) chains of very low sulfated chondroitin sulfate proteoglycans (CSPGs) in placenta mediate the IRBC adherence. While it is known that partially sulfated but not fully sulfated C4S effectively binds IRBCs, structural interactions involved remain unclear and are incompletely understood. In this study, structurally defined C4S oligosaccharides of varying sulfate contents and sizes were evaluated for their ability to inhibit the binding of IRBCs from different P. falciparum strains to CSPG purified from placenta. The results clearly show that, with all parasite strains studied, dodecasaccharide is the minimal chain length required for the efficient adherence of IRBCs to CSPG and two 4-sulfated disaccharides within this minimal structural motif are sufficient for maximal binding. Together, these data demonstrate for the first time that the C4S structural requirement for IRBC adherence is parasite strain-independent. We also show that the carboxyl group on nonreducing end glucuronic acid in dodecasaccharide motif is important for IRBC binding. Thus, in oligosaccharides containing terminal 4,5-unsaturated glucuronic acid, the nonreducing end disaccharide moiety does not interact with IRBCs due to the altered spatial orientation of carboxyl group. In such C4S oligosaccharides, 14-mer but not 12-mer constitutes the minimal motif for inhibition of IRBC binding to placental CSPG. These data have important implications for the development and evaluation of therapeutics and vaccine for placental malaria.Biochemistry 12/2008; 47(47):12635-43. DOI:10.1021/bi801643m · 3.38 Impact Factor
Article: Ex vivo expansions of megakaryocytopoiesis from placental and umbilical cord blood CD34(+) cells in serum-free culture supplemented with proteoglycans extracted from the nasal cartilage of salmon heads and the nasal septum cartilage of whale.[Show abstract] [Hide abstract]
ABSTRACT: As a possible approach to the treatment of thrombopocytopenia, the ex vivo expansion of megakaryocytic progenitor cells may be a useful tool to accelerate platelet recovery in vivo. Our objective was to assess the promoting effect of proteoglycans in a serum-free culture condition using human cord blood CD34(+) cells. Highly purified proteoglycan (PG) extracted from the nasal cartilage of salmon heads and the nasal septum cartilage of a whale were applied to the ex vivo expansion of megakaryocytopoiesis and thrombopoiesis from placental and umbilical cord blood CD34(+) cells in serum-free cultures stimulated with a combination of thrombopoietin (TPO) and interleukin-3 (IL-3). Each PG (0.5 and 5 mug) was applied to the culture with three different concentrations of TPO (50, 5 and 0.5 ng/ml) and IL-3 (100, 10 and 1 ng/ml). Both of the PGs showed no promoting effects on the mononuclear cell proliferation rate in any of the cultures. However, the whale-PG promoted the generation of megakaryocytic progenitor cells and megakaryocytes in the culture with a lower dose of cytokines, respectively. In addition, whale-PG led to a significant increase in CD42a(+) particles which seemed to be platelets. While the salmon-PG failed to promote such production in almost all of the cultures. Although whale-PG is an attractive molecule for the ex vivo expansion of human megakaryocytopoiesis, its action may depend on the glycosaminoglycans sulfation pattern and the ability of the binding affinity and the kinetics to interact with the cytokines and hematopoietic stem/progenitor cells.Life Sciences 06/2008; 82(19-20):1023-31. DOI:10.1016/j.lfs.2008.03.001 · 2.30 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: Proteoglycans (PG) are macromolecules composed of glycosaminoglycan chains covalently attached to a protein core. In this study, we examined the effects of PG on dextran sulfate sodium (DSS)-induced experimental colitis in rats. First, to examine whether PG may ameliorate acute established DSS colitis, PG was administered orally for 5 days to the model animals. We evaluated the effects of PG on the basis of clinical symptoms, hematological analysis, macroscopic observation, and microscopic examination. We then examined whether PG administered orally to rats was detectable in their colonic lumen. After administration of PG, the colonic contents were collected, and the molecular weight of PG in the sample was analyzed by gel filtration high-performance liquid chromatography. Furthermore, we examined whether orally administered PG affected the concentrations of short-chain fatty acids (SCFAs) in the colonic feces. Orally administered PG ameliorated the clinical symptoms of bloody stools and diarrhea, and attenuated the increase in the white blood cell count in rats with established DSS colitis. Histologically, orally administered PG reduced the degree of mucosal erosion and inflammatory cell infiltration into the erosive area induced by DSS. Orally administered PG was detected in rat colon, although its molecular weight was slightly decreased. Orally administered PG significantly increased the concentration of total SCFAs and n-butyrate in rat colonic feces. This is the first study to indicate that exogenous PG ameliorates experimental colitis, suggesting the potential usefulness of PG for clinical treatment of colitis.Digestive Diseases and Sciences 06/2008; 53(12):3176-83. DOI:10.1007/s10620-008-0304-0 · 2.55 Impact Factor
Article: Up-regulation of hyaluronan synthase genes in cultured human epidermal keratinocytes by UVB irradiation.[Show abstract] [Hide abstract]
ABSTRACT: Hyaluronan controls keratinocyte proliferation and regeneration. We examined effect of UV on the expression of hyaluronan synthases (HASs) and hyaluronidases in cultured normal human newborn foreskin epidermal keratinocytes, NHEK(F). HAS3 mRNA was expressed predominantly and HAS2 mRNA expressed in lesser amounts and both were up-regulated after a single irradiation with moderate UVB but hyaluronidases was unchanged. Increased accumulation of hyaluronan in the culture medium mirrored the UVB-induced increase in the mRNA levels of HAS3 and HAS2. Unexpectedly, hyaluronan derived from UVB-irradiated and non-irradiated cells had identical size distribution. Increased expression of KGF and IL-1beta was detected just prior to the increase of HAS3 and HAS2 mRNAs after UVB irradiation. Antibody-neutralization study revealed that KGF and/or IL-1beta were at least involved in the up-regulation of HAS3 and HAS2 expressions. UVB-irradiated cells may enhance hyaluronan production to maintain homeostasis through up-regulation of HAS3 and HAS2 genes via cytokine response mechanism.Archives of Biochemistry and Biophysics 04/2008; 471(1):85-93. DOI:10.1016/j.abb.2007.12.004 · 3.04 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: Hyaluronate plays an important role in the regulation of cervical function during parturition. In our previous study we showed that 4-methylumbelliferone (MU) suppresses hyaluronate synthesis by cultured human skin fibroblasts. The present study investigated the effects of MU on fibroblasts obtained from the human uterine cervix and assessed the possibility of controlling cervical ripening with MU. Human uterine cervical fibroblasts were collected from uterine cervices obtained from the uteri of three patients who had a total hysterectomy for uterine myoma at Hirosaki University Hospital. The fibroblasts were cultured in Dulbecco's modified Eagle's medium until confluence. They were then cultured in medium containing [3H]glucosamine (0.074 MBq/mL) with various MU doses. Hyaluronate synthesis was evaluated by assessing the incorporation of [3H]glucosamine into the soluble fraction of hyaluronate. Three independent studies were carried out on each specimen to clarify whether MU causes compositional changes or promotes hyaluronate degradation, whether the inhibitory effects of MU on hyaluronate synthesis are dose-dependent, and whether the effects of MU are reversible. MU added to the medium of the cultured cells reduced the synthesis of hyaluronate in a dose-dependent manner. After MU was removed from the medium, hyaluronate synthesis recommenced, and the amount of [3H]hyaluronate synthesized was similar to the control level. MU inhibits the synthesis of hyaluronate in human uterine cervical fibroblasts.Journal of Obstetrics and Gynaecology Research 01/2008; 33(6):772-6. DOI:10.1111/j.1447-0756.2007.00654.x · 0.93 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: Currently established biotechnologies are mainly based on genetic engineering and protein engineering, and they provide a number of valuable recombinant proteins. These technologies have brought benefits to medicine by enabling the production of various drugs. However, genetically produced recombinant proteins often lack entirely or partially their native sugar chains or have sugar chains that are different from the original sugar chains, thus being apt to exert insufficient specific bioactivities or to be unstable. The cause of this lack of sugar chains of recombinant proteins is that, DNA contains genetic information only on amino acid sequences but not on the biosynthesis of sugar chains that link to proteins. This problem could be solved by technologies to attach sugar chains to sugar chain-deficient recombinant protein. Moreover, attaching artificially synthesized bioactive sugar chains to protein would make it possible to create glycoproteins with additional biological activity. We focused on the transglycosylation activity of endoglycosidases acting on proteoglycan and developed methods for the reconstruction of their sugar chains, glycosaminoglycan (GAG), and for attachment of GAGs to protein.12/2007: pages 173-176;
Article: Application of proteoglycan extracted from the nasal cartilage of salmon heads for ex vivo expansion of hematopoietic progenitor cells derived from human umbilical cord blood.[Show abstract] [Hide abstract]
ABSTRACT: Highly purified proteoglycan (PG) extracted from the nasal cartilage of salmon heads was applied to the ex vivo expansion of hematopoietic progenitor cells prepared from human umbilical cord blood in serum-free cultures supplemented with the combination of early-acting cytokines, thrombopoietin (TPO), interleukin-3 (IL-3) and stem cell factor (SCF). PG showed no promoting effects on the cell proliferation rate; however, they promoted the generation of progenitor cells for granulocyte-macrophages, erythrocytes and/or megakaryocytes in culture with TPO alone or SCF plus TPO. However, no promoting effect was observed in a combination of IL-3 plus SCF, which showed the highest cell proliferation rate. PG failed to promote the generation of mixed colony-forming units (i.e. the relatively immature cells in hematopoiesis). These results suggest that PG acts on the relatively mature stem/progenitor cells, and may function as a regulatory factor in the differentiation pathway of hematopoiesis.Glycoconjugate Journal 08/2007; 24(4-5):251-8. DOI:10.1007/s10719-007-9033-4 · 1.95 Impact Factor
Article: Diversity in the degree of sulfation and chain length of the glycosaminoglycan moiety of urinary trypsin inhibitor isomers[Show abstract] [Hide abstract]
ABSTRACT: Five isomers with different electric charge were fractionated from human urinary trypsin inhibitor (UTI) by anion exchange HPLC. Intact low-sulfated chondroitin 4-sulfate chains from the isomers were analyzed by HPLC and mass spectrometry. Unsaturated disaccharide composition analysis of the chondroitin sulfate chain revealed that the five isomers differ in the numbers of 4-sulfated disaccharide units. Intriguingly, we detected the presence of multiple novel isomers with different numbers of non-sulfated disaccharide units even in the same charge isomer fraction. Our results demonstrate that UTI can vary in terms of both the degree of sulfation and the length of the low-sulfated chondroitin 4-sulfate chain.Biochimica et Biophysica Acta 03/2007; 1770(2):171-7. DOI:10.1016/j.bbagen.2006.09.026 · 4.66 Impact Factor
Article: Salmon cartilage proteoglycan modulates cytokine responses to Escherichia coli in mouse macrophages.[Show abstract] [Hide abstract]
ABSTRACT: Proteoglycans (PGs) are complex glycohydrates, which are composed of core proteins and glycosaminoglycans and widely distributed in connective tissues and on the cell surface of mammalian tissues. We investigated the effect of PG extracted from salmon cartilage on cytokine responses to stimulation with heat-killed Escherichia coli (HKEC) in a mouse macrophage cell line, RAW264.7. PG exhibited the suppression of tumor necrosis factor-alpha production compared with chondroitin 4 sulfate (C4S) and chondroitin 6 sulfate (C6S). PG also revealed the up-regulation of interleukin-10 production. HKEC-induced Toll-like receptor 4 (TLR4) and inducible nitric oxide synthase expression was dose-dependently suppressed by treatment with PG, C4S or C6S, and the PG showed the strongest suppressive effect among 3 compounds. Only PG dramatically up-regulated the expression of signal transducer and activator of transcription 3 (STAT3), and the phosphorylation of STAT3 in mouse macrophages. Our results suggested that the novel interaction might exist between the extracellular matrix and immune system.Biochemical and Biophysical Research Communications 01/2007; 351(4):1005-10. DOI:10.1016/j.bbrc.2006.10.146 · 2.28 Impact Factor
Article: L457F missense mutation within the 2B rod domain of keratin 9 in a Japanese family with epidermolytic palmoplantar keratodermaBritish Journal of Dermatology 10/2006; 155(3):624-6. DOI:10.1111/j.1365-2133.2006.07358.x · 4.10 Impact Factor
Article: Efficient and widely applicable method of constructing neo-proteoglycan utilizing copper(I) catalyzed 1,3-dipolar cycloaddition[Show abstract] [Hide abstract]
ABSTRACT: Efficient constructions of two types of neo-proteoglycan are described. Enzymatically prepared alkyne containing chondroitin 6-sulfate chains and chemically synthesized azido group having compounds are linked by utilizing the copper(I) catalyzed 1,3-dipolar cycloaddition.Tetrahedron Letters 10/2006; 47(42):7455-7458. DOI:10.1016/j.tetlet.2006.08.041 · 2.39 Impact Factor
Article: Study of hyaluronan synthase inhibitor, 4-methylumbelliferone derivatives on human pancreatic cancer cell (KP1-NL).[Show abstract] [Hide abstract]
ABSTRACT: The structure of 4-methylumbelliferone (MU) consists of coumarin with 4-methyl group and 7-hydroxy group. MU inhibits HA synthesis and pericellular HA matrix formation. In this study, we used 10 MU derivatives which have hydroxy groups and methyl groups at various positions of coumarin to investigate a more effective HA inhibitor than MU. First, human pancreatic cancer cell (KP1-NL) growth assay was analyzed by Alamar Blue to determine the non-toxic concentration of MU derivatives, and the inhibitory effect on HA synthesis in the cell cultures was analyzed by HA measuring kit. Next, cell surfaces of cancer cells were analyzed by particle-exclusion assay. In conclusion, both hydroxy and methyl groups are necessary for HA inhibition by MU, and two hydroxy groups inhibited HA synthesis more strongly than MU.Biochemical and Biophysical Research Communications 08/2006; 345(4):1454-9. DOI:10.1016/j.bbrc.2006.05.037 · 2.28 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: The extracellular matrix plays an essential role in normal hematopoiesis. Proteoglycans and glycosaminoglycans (GAG) are major components of the matrix. In this study, the effects of various GAG on the proliferation and differentiation of CD34+ megakaryocytic progenitor cells (CFU-Meg) were evaluated in vitro. CD34+ cells were highly purified from steady-state human peripheral blood. The GAG tested were hyaluronic acid (from humans, pigs and roosters), keratan sulfate, heparan sulfate, chondroitin sulfate (from whale, shark or squid cartilage) and dermatan sulfate (DS). When used alone, none of the GAG supported the clonal growth of CFU-Meg; however, in cultures stimulated by recombinant human thrombopoietin, human hyaluronic acid, whale chondroitin sulfate and DS significantly enhanced such growth. In particular, the addition of DS resulted in increases of about 1.3-fold, 1.6-fold and 2.0-fold in the numbers of total cells, megakaryocytes and CFU-Meg, respectively, compared with the control culture stimulated by thrombopoietin alone after 9-12 days of serum-free liquid culture. Furthermore, DS induced the generation of hyperploid megakaryocytes and promoted pro-platelet formation. Chemical fragmentation and desulfation of DS showed that a chain of at least 12 saccharides is required for colony-promoting activity and that the sulfate groups play an essential role. DS acts on an immature population of CD34+ cells, stimulates the proliferation of CFU-Meg, and enhances the terminal maturation of megakaryocytes and thrombopoiesis. These results suggest that DS has a wide spectrum of action in promoting megakaryocytopoiesis and thrombopoiesis.Haematologica 05/2006; 91(4):445-51. · 5.94 Impact Factor
Article: 4-methylumbelliferone, a hyaluronan synthase suppressor, enhances the anticancer activity of gemcitabine in human pancreatic cancer cells.[Show abstract] [Hide abstract]
ABSTRACT: Hyaluronan (HA) is a ubiquitous, major component of the pericellular matrix and is necessary for various physiological processes. It plays a very important role in biological barriers. We previously reported that 4-methylumbelliferone (MU) inhibits HA synthesis and pericellular HA matrix formation in cultured human skin fibroblasts, Streptococcus equi FM100, and B16F10 melanoma cells. We hypothesized that MU-mediated inhibition of HA synthesis and pericellular HA matrix formation would increase the efficacy of anticancer drugs. We have already demonstrated in vitro, using a sandwich binding protein assay and a particle exclusion assay, that MU inhibits HA synthesis and formation of the pericellular HA matrix, respectively, in human KP1-NL pancreatic cancer cells. AlamarBlue assay revealed that the anticancer effect of gemcitabine in KP1-NL cells was increased by pretreatment with MU. In vivo simultaneous administration of MU and gemcitabine to tumor-bearing mice with severe combined immunodeficiency disease (SCID) decreased the size of the primary and metastatic tumors more than did gemcitabine alone. These data strongly suggest that a combination of MU and gemcitabine is effective against human pancreatic cancer cells. MU may have potential as a chemosensitizer and may provide us with a new anticancer strategy.Cancer Chemotherapy and Pharmacology 02/2006; 57(2):165-70. DOI:10.1007/s00280-005-0016-5 · 2.57 Impact Factor
Article: Tissue-specific downregulation of type VII collagen gene (COL7A1) transcription in cultured epidermal keratinocytes by ultraviolet A radiation (UVA) and UVA-inducible cytokines, with special reference to cutaneous photoaging[Show abstract] [Hide abstract]
ABSTRACT: Background Type VII collagen is the major component of anchoring fibrils, which stabilize the attachment of the basement membrane zone to the dermis. Expression of type VII collagen in epidermal keratinocytes and formation of anchoring fibrils in the basement membrane zone are reduced in photoaged skin, suggesting their involvement in the pathophysiology of photoaging.Objective To investigate the effects of ultraviolet A radiation (UVA) and UVA-inducible cytokines, tumor necrosis factor (TNF)-α and interleukin (IL)-1β on type VII collagen gene (COL7A1) transcription in epidermal keratinocytes.Methods Cultured epidermal and HaCaT keratinocytes were transiently/stably transfected with plasmid constructs containing sequential 5′-end deletions of the COL7A1 promoter, linked to luciferase or the GFP gene. Twenty-four hours after treatment with either UVA, TNF-α or IL-1β, luciferase activity and GFP expression of TNF-α and IL-1β were detected by luminometer or fluorescence microscopy, respectively.ResultsUVA, TNF-α and IL-1β all decreased COL7A1 promoter activity in cultured epidermal keratinocytes as well as GFP expression in HaCaT keratinocytes. Deletion analysis revealed that the UVA- and cytokine-responsive region of COL7A1 lies between nucleotides −524 and −22.ConclusionUVA, TNF-α and IL-1β inhibit COL7A1 expression at the transcriptional level by acting on nucleotides −524 to −22 of the promoter region. These results suggest that UVA-induced downregulation of COL7A1 transcription in epidermal keratinocytes diminishes anchoring fibrils formation, resulting in skin fragility. Additional external factors including physical forces and UVB radiation in the sun-exposed areas may further promote deep wrinkle formation.Journal of Dermatological Science Supplement 12/2005; 1(2). DOI:10.1016/j.descs.2005.06.004
Article: A hyaluronan synthase suppressor, 4-methylumbelliferone, inhibits liver metastasis of melanoma cells.[Show abstract] [Hide abstract]
ABSTRACT: 4-Methylumbelliferone (MU) inhibits the cell surface hyaluronan (HA) formation, and that such inhibition results in suppression of adhesion and locomotion of cultured melanoma cells. Here, we examine the effect of MU on melanoma cell metastasis in vivo. MU-treated melanoma cells showed both decreased cell surface HA formation and suppression of liver metastasis after injection into the mice. Oral administration of MU to mice decreased tissue HA content. These HA knock-down mice displayed suppressed liver metastasis. Thus, both cell surface HA of melanoma cells and recipient liver HA can promote liver metastasis, indicating that MU has potential as an anti-metastatic agent.FEBS Letters 06/2005; 579(12):2722-6. DOI:10.1016/j.febslet.2005.03.079 · 3.34 Impact Factor
Article: Keratinocyte-specific modulation of type VII collagen gene expression by pro-inflammatory cytokines (tumor necrosis factor-alpha and interleukin-1beta).[Show abstract] [Hide abstract]
ABSTRACT: Previous studies have shown that pro-inflammatory cytokines such as tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta up-regulate type VII collagen gene (COL7A1) expression in cultured dermal fibroblasts. The present study was designed to investigate the effects of TNF-alpha and IL-1beta on COL7A1 expression in epidermal keratinocytes. We demonstrated that both TNF-alpha and IL-1beta reduced COL7A1 expression in epidermal keratinocytes in an additive manner, whereas they increased COL7A1 expression in dermal fibroblasts. Thus, regulation of COL7A1 by pro-inflammatory cytokines is cell type specific. In particular, the inhibitory effects of TNF-alpha and IL-1beta occurred, at least in part, at the transcriptional level. Finally, we demonstrated that TNF-alpha and IL-1beta enhanced the TGF-beta-mediated up-regulation of COL7A1 expression in HaCaT keratinocytes, suggesting that the combination of TGF-beta and TNF-alpha or IL-1beta induces a signaling pathway that is completely different from that induced by either pro-inflammatory cytokine alone.Experimental Dermatology 05/2005; 14(4):289-94. DOI:10.1111/j.0906-6705.2005.00316.x · 4.12 Impact Factor
Top Journals
Hirosaki University
Khirosaki, Aomori, Japan
- • Department of Biochemistry and Genome Biology
- • School of Medicine
- • Department of Science Radiological Technology
Aomori Prefectural Central HospitalAomori, Aomori Prefecture, Japan
Northwestern UniversityEvanston, Illinois, United States


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Beautiful Floral Pattern Silver Plate Meat Fork
Tis the season ladies when we all seem to need extra serving pieces or is that everyday?. Seems like I always need one more serving spoon or meat fork, one more ladle. I have not a clue what the name of this pattern is or the maker. What I do know is that it is just beautiful and quite handsome. I love the floral patterns of this era, which I date to the early 1900's. The flower looks like an Apple Blossom to me. The fork is in very, very nice vintage condition. You will not be disappointed. I have collected lots of assorted serving pieces this year and am listing them now in time for the holidays.
Item ID: B754
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routes du bonheur Suggestions for itineraries to discover the world
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60 Years with Relais & Châteaux, along the Nationale 7 Road
By Michel Troisgros
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Switzerland : A tour of Switzerland on a Harley Davidson
By Pierre Berclaz
Maître de maison of Les Sources des Alpes
Around Vienna and Lower Austria
By Birgit Reitbauer
Owners of the Steirereck im Stadtpark restaurant
From Buenos Aires to Patagonia
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The Italian Lakes
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Owner and Grand Chef, la Villa Crespi
Between the vineyards of the Douro Valley
By Antonio Saraiva
President of the Association of Port Wine Companies
From Potsdam to Göttingen
By Ralf Kutzner
Maître de Maison of the Bülow Palais hotel
Destination Corsica, the shores of the Mediterranean
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Circuit around the coast of Brittany by The Sentier des Douaniers
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The garden islands, from Hong Kong to Taiwan,
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I was born in Joigny, the Gate to Burgundy, as the sign at the entrance of the town suggests. It is where the region opens its arms to welcome you. I was not rocked by vineyard but by the Yonne River. This stunning course of water flows beneath our windows and is for me both soothing and inspiring. I would like to wake up in the middle of the night and be alone at the water's edge with my line, waiting to catch some fish. Burgundy is a real paradise for nature lovers and those who want a bit of peace. It's a region where we can go from the vineyards to the wineries and form the abbeys to the forest; a place where the diversity of climates may soon be classified as world heritage.
Relais & Châteaux proposes its Routes du Bonheur for your inspiration: they are suggestions of itineraries that you can adapt to your preferences and desired experiences. Our advisors are at your disposal to individualise your routes and help you make reservations at our properties.Example for a four-night stay from €898** Minimum indicative rate per person, subject to availability, on the basis of a double room with double occupancy, including accommodation, breakfast and dinner (menu, without beverages) in the properties suggested for the itinerary.Activities on site and nearby must be reserved by you.
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Joigny's market
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La Fabuloserie
This outsider art museum is rather unknown, created by the architect and painter-sculptor Alain Bourbonnais in the sheds of his house in the countryside of Dicy. The museum houses wonderful pieces of atypical art imagined by eccentric fantasist and inspired artists who were farmers, miners or just young herdsmen. In the garden, don't miss the Petit Pierre's ride, a thoroughly poetic work which I always take pleasure in discovering.
La Fabuloserie
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Fontenay abbey
A bakery at Beaune
A visit to David Duband's Domaine
Truffles and Castles
Relais & chateaux Restaurant Auberge de l'Ile, Lyon
This is an unusual property, snuggled in the heart of Barbe Island, surrounded by the water of the Saône. We find ourselves in a former refectory of a medieval monastery, so near to Lyon's town centre and yet so cut off. Another great chef from Lyon, Jean-Christophe Ansanay-Alex has carried high the restaurant which once belonged to his father. He offers today a succulent, subtle and minimalistic cuisine.
Auberge de l'Île
Cluny Abbey
Lamartine House Maison de Lamartine
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Earn More Money By Switching Jobs
by Chris Malone
posted Jun 24 2014 2:58AM
Time for a new job. A new study reveals that people who stay at the same job for more than two years earn 50 percent less over their lifetime than those who change companies more frequently.
Forbes magazine says
the average raise a worker can expect in 2014 is three percent, which is really just about one percent after inflation. By contrast, the average raise an employee receives for starting at a new job is between ten and 20 percent, and in some cases as high as 50 percent. Loyal employees lose out in the long-run because many businesses have been forced to freeze payroll and decrease salaries following the 2008 recession. Bethany Devine, a Silicon Valley hiring manager, says, "There is often a limit to how high your manager can bump you up since it's based on a percentage of your current salary. However, if you move to another company, you start fresh and can usually command a higher base salary."
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prune picker
This is the blog of a prune picker. Retired oilfield. I am an old man. Will be 90 next July 20. I blog a lot about my body. As I approach death some things work erratically. I am able to attend sports and bluegrass events. I attend swim class three times a week. Some of my blogs might be interesting. A lot of my blogs are silly and trivial. Read at your own risk.
Sunday, November 14, 2010
Meeting of Northeast Louisiana Genealogy Society
Posted by Chuck Monson at 5:26 PM
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Is it this cemetery?ReplyDelete
Old City Cemetery
18th & DiSiard Streets
Monroe, LA 71201
As this cemetery is listed as accepting current burials with the Louisiana Cemetery Board, the city is in charge of upkeep.
Here is the contact number to file a complaint about the city to the Louisiana Cemetery Board.
Photographs and dates of poor upkeep are oftentimes most helpful.
3445 N. Causeway Boulevard, Suite 700
Metairie, Louisiana 70002
Telephone (504) 838-5267
Toll Free (866) 488-5267
Fax (504) 838-5289
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text: I have NEVER got into a club for free, or ahead of the queue. I have NEVER expected anyone to pay for me on a date, and can't even remember the last time it happened. I absolutely do not agree that there is a huge range of beautiful flattering clothes just waiting for me in every shop - most things don't come in my size, or are too expensive, or look hideous, or all three at the same time! My body type is definitely not considered the archetype of sexy, I can barely even find a bra that doesn't try and attack me all day. I'm sure these nice men are being honest in what they think, but their idea of what being a woman is seems to be based on TV/films and stereotypes rather than real life.


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After a slow start, the defending Stanley Cup champions are beginning to look the part thanks to goaltender John Grahame.
Grahame will likely try to help the the Tampa Bay Lightning extend their season-high winning streak to six games when they meet the Anaheim Mighty Ducks.
Tampa Bay's current winning streak is its longest since a franchise record eight-game run from Feb. 23-March 6, 2004.
If Grahame gets the start, he will also try extend his personal franchise-record winning streak to 10 games. Grahame needed to make just 13 saves in the Lightning's 3-1 win Saturday over the Nashville Predators and broke the record of eight wins in a row set by Nikolai Khabibulin from Feb. 23-March 6, 2004.
Despite his success, Grahame is careful not to take too much credit.
"We try not to have individual awards on this team," Grahame said. "That's what makes us successful. The team has won nine games. That's the way I look at it. We all contribute during the game."
Martin St. Louis, a key to the Tampa Bay's run to the Cup, will try to extend his goal-scoring streak to five games. He has just one assist in eight lifetime games versus Anaheim.
The Ducks return home after dropping two of three on an Eastern road trip. Rob Niedermayer and Teemu Selanne scored in a 3-2 loss Monday to the Toronto Maple Leafs.
The Mighty Ducks failed to score in eight power play opportunities and are 1-for-22 with the man advantage in their last four games.
"We showed up flat for some reason," Ducks goalie Jean-Sebastien Giguere said. "It's unacceptable. We're better than that. We're a skating team and we can't afford to not show up for 60 minutes."
Giguere is 2-1-0 with a 1.30 goals-against average and .950 save percentage in three games against the Lightning.
Anaheim holds a 9-7-1 edge in the series.
STANDINGS (through Dec. 13): Lightning - 37 points, 2nd place, 3 PB, Southeast Division. Mighty Ducks - 31 points, 4th place, 8 PB, Pacific Division.
TEAM LEADERS: Lightning - Fredrik Modin, 14 goals; Brad Richards, 23 assists; Vaclav Prospal, 35 points; Pavel Kubina, 48 PIM. Mighty Ducks - Teemu Selanne, 16 goals and 27 points; Scott Niedermayer, 17 assists; Todd Fedoruk, 57 PIM.
SPECIAL TEAMS (through Dec. 13): Lightning - Power play: 14.8 percent (27 for 182), tied for 23rd in NHL. Penalty killing: 84.5 percent (126 for 149), 6th. Mighty Ducks - Power play: 14.7 percent (28 for 190), tied for 25th. Penalty killing: 83.7 percent (175 for 209), 8th.
GOALTENDERS: Lightning - Grahame (14-8-1, 1 SO, 2.72 GAA); Sean Burke (3-1-2, 0, 2.77). Mighty Ducks - Giguere (7-4-5, 0, 2.69); Ilya Bryzgalov (6-9-0, 0, 2.51).
2003-04 SEASON SERIES: Mighty Ducks, 1-0.
LAST MEETING: Dec. 29, 2003; Mighty Ducks, 2-0. At Tampa, Fla., Giguere stopped 31 shots for his only road shutout of the season, and Petr Sykora had one goal and one assist.
ROAD/HOME RECORDS: Lightning - 7-5-2 on the road; Mighty Ducks - 10-6-2 at home.
Team Comparison
Blog Coverage from SB Nation
Sheldon Souray D, Tim Jackman RW, Korbinian Holzer D


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