text:
Technical Papers and Presentations
Comparison of Darcy's Law, the Brinkman Equation, the Modified Navier-Stokes Equation and the Pure Diffusion Equation in PEM Fuel Cell Modeling
Z. Shi and X. Wang
Oakland University, Rochester, MI, USA
A two dimensional isothermal single phase PEM fuel cell model is developed and implemented in COMSOL Multiphysics, where Darcy's law, the Brinkman equation, the modified Navier-Stokes equation, and the pure diffusion equation are applied separately in porous electrodes. Three values of GDL permeability are investigated. Additionally, the order of the magnitude of each term in the modified N-S ...
State of Charge (SOC) Governed Fast Charging Method for Lithium Based Batteries
F. Naznin[1]
[1]TVS Motor Company Ltd., Hosur, Tamil Nadu, India
The proposed State of Charge (SOC) governed fast charging method for secondary lithium based batteries charges a battery many times faster than the normal Constant Current-Constant Voltage (CC-CV) charging and reduces the side-effects generally accompanied by various fast charging methods. The proposed charging algorithm takes into account the varying internal impedance of the battery at ...
Simulation of Cyclic Voltammetry of Ferrocyanide/Ferricyanide Redox Reaction in the EQCM Sensor
H. Kwon, and E. Akyiano
Dept. of Engineering and Computer Science
Andrews University
Berrien Springs, MI
In this paper, the cyclic voltammetry behavior of Ferrocyanide/Ferricyanide, which is commonly used for electrochemical DNA detection experiment, was studied in the commercial EQCM-D setup (Q-sense) using the COMSOL Multiphysics. The model was established in a 3D geometry of QCM liquid cell. The simulation shows depletion of concentration of ferrocyanice following applied electrode potential. ...
Simulation of Current Density for Electroplating on Silicon Using a Hull Cell
F. Lima[1], U. Mescheder[1], H. Reinecke[3]
[1]Hochschule Furtwangen University, Furtwangen, Baden-Wuerttemberg, Germany
[3]Institut für Mikrosystemtechnik, Freiburg im Breisgau, Baden-Wuerttemberg, Germany
Electrodeposition has a major advantage over other methods of thin film deposition. It allows deposition at atmospheric pressure and room temperature, requiring inexpensive equipment. However, there are several parameters which can influence an electroplated metal layer quality. The current density distribution is taken into consideration. The Hull cell is an electrodeposition tank with a ...
Modeling of Supercapacitor
G. Madabattula[1], S. K. Gupta[1]
[1]Department of Chemical Engineering, Indian Institute of Science, Bangalore, Karnataka, India
Low cost high energy density batteries that can be charged and discharged rapidly are required in a number of applications. Tapping energy from renewal resources such as solar, wind and tide requires rapidly generated energy to be first stored and then used round the clock. Storing energy of a moving vehicle as it slows down and recovering it to accelerate the vehicle later can significantly ...
Simulation of Production Processes using the Multiphysics Approach: The Electrochemical Machining Process
R. van Tijum
Advanced Technology Center, Philips Consumer Lifestyle, Drachten, The Netherlands
Redmer van Tijum studied Applied Physics at the University of Groningen. In 2006, he received his PhD title on 'Interface and surface roughness of polymer metal laminates' in the field of Material Science at the University of Groningen. After that he became research and development engineer at Philips, where he focussed his attention on the improvement of production processes mainly ...
Mathematical Modeling of a Lithium Ion Battery
R. E. White[1], and Long Cai[2]
[1]R.E. White & Associates LLC, Columbia, South Carolina, USA
[2]Department of Chemical Engineering, University of South Carolina, Columbia, South Carolina, USA
The existing lithium ion battery model in COMSOL's Multiphysics software is extended to include the thermal effects. The thermal behavior of a lithium ion battery is studied during the galvanostatic discharge process with and without a pulse. The existing lithium ion battery model in COMSOL 3.5a is extended by adding an energy balance and the temperature dependence of properties of ...
Analysis of 3-D Printed Structural Components for Cube Satellites
C. Herzfeld[1]
[1]SPAWAR Systems Center (SSC) ATLANTIC, Charleston, SC, USA
Additive manufacturing uses 3D printing to build physical parts from CAD-based designs. The technology includes fused deposition modeling (FDM) and selective laser sintering (SLS) methods. 3-D printing is of particular interest for smaller, one-of-a-kind, customizable products. A cube satellite (CubeSat) containing fiber reinforced SLS parts has been successfully launched (Ref 1). Lower ...
Numerical Modeling of the Bistability of Electrolyte Transport in Conical Nanopores
H. White[1], L. Luo[1]
[1]Department of Chemistry, University of Utah, Salt Lake City, UT, USA
A characteristic feature of nanochannels is that surface properties (e.g., electrical charge) play a more significant role in the transport of fluid and electrolyte. Two oppositely directed flows (electroosmotic flow and pressure-driven flow) determine the flow profile at the nanopore orifice as well as electrolyte distribution. Once there are two electrolyte solutions with different ...
Analysis of Electro-Thermal Hot Spot Formation in Li-Ion-Battery-Cells
W. Beckert[1], C. Freytag[1], T. Frölich[1], G. Fauser[1]
[1]Fraunhofer IKTS, Dresden, Germany
The presented model approach offers a computational efficient tool to analyze the influences of geometrical design details, material selection and operational conditions on the electro-thermal behavior of a full Li ion battery cell geometry. It considers typical aspects as anisotropic winding structure, electro-thermal coupling and nonlinear electrical characteristics for moderate computational ...


text:
A remake of '80s classic "Escape from New York" has been on the cards for years – and it might remain that way, at least for a few more.
Producer Joel Silver ("Lethal Weapon", "Commando") tells Collider that although his prod co has ambitious plans for "New York" – which he envisions as a prequel trilogy – they haven't yet made it to script stage yet.
"There was a videogame that came out a few years ago called Arkham City, which shows how when Gotham became this kind of walled prison and how it became a walled prison. And they never deal with that in the story of Escape from New York, so part of our idea was to kind of see how the city became this walled prison and how the Snake Plissken character was a hero and how he became not looked at as a hero. And then, in the middle of the story, would be the movie that we, you know, previously saw about the President's daughter goes down, he has to go in and get her. And then, you know, they did a sequel, Escape from LA, but I would like to then kind of find a way to have New York go back to a place that we'd like to see what it is today."
The veteran action-movie producer, out promoting the new film "Non-Stop" starring Liam Neeson, says "there is a way to tell the story in three ways, but we haven't got there yet and we're just starting."
- Trailer : Masterminds - March 31, 2015
- When will we see the next Star Wars trailer!? - March 31, 2015
- Shrek to appear in new Puss in Boots sequel? - March 31, 2015
- Disney developing live-action Mulan - March 31, 2015
- Tron 3 ascends into title territory - March 31, 2015
- Superhero Movie Updates : X-Men, Suicide Squad, Deadpool, The Flash, TMNT - March 31, 2015
- NBC bringing The Wiz to Television! - March 31, 2015
- Basu boards Metal Gear Solid - March 31, 2015
- Blunt joins Krasinski in Animal Crackers - March 31, 2015
- Aussie film These Final Hours adapted for Television - March 31, 2015
Against the Current - the band, not adventures in dangerous swimming 101
Zedd - If our love is tragedy, why are you my remedy? (Well, answer my question!)
Arrow (Okay, Felicity from Arrow!)
Chrissy Costanza (cat eyes and buttery lyrics!)
Girls (TV) (Okay, Allison Williams!)
Movies - especially when they play in the dark.
Twin Peaks (TV)
Friends (TV) (It had me at "No way are you cool enough to pull Clint"; damn straight, Chandler!)
Traveling - preferably where water is, so I can splash someone!
Star Wars trilogy - no, the other one, fella!
Alex G - far more talented than her younger brother Alex H
Cameron Crowe movies - Say Anything..., Jerry Maguire, Almost Famous
The sign 'Free Wi-Fi'.
Reenacting dance/song scenes from "Grease" with my little girl (hey! Wait till you see my 'Summer Lovin'! - don't judge)
Die Hard - 40 stories of Sheer Adventure!
Alex Goot & Friends (his enemies aren't half as talented!)
Cooking up a nice dish and sitting in the entertainment area, on a cool night, basking in it's greatness.
Inflatable kids pools full of Vodka Lime Crush.
Acidic Email from angry, over passionate teenagers after I trash something "Twilight"-related on the site. Sparkle elsewhere.
My baby girl's big, caring heart.

subset: commoncrawl


text:
And it is a glorious thing. I fried everything I could possibly fry over the weekend, and I didn't even watch the Super Bowl. The Scotch Egg pictured above was but one of three served for breakfast on Sunday morning. Of the three people living in the house, I was the only one who ate them, but they turned out pretty good for my first time making those delicious little goddamnits. This is also the first time I've had a fryer at home, and I'm pretty psyched. Expect me to share more golden brown abominables in the future.
Also, expect me to keep you updated more frequently. Re-launching this domain a month ago was intended to get me writing a lot more, but I've managed to envision some much more engaging projects to share with you this year, and the writing has gone toward those other projects. I don't want to reveal too much just yet, but I'll give you a hint: I know that people don't really read anymore, and I'll probably reach a lot more people when I just accept that.
So I'll try to drop a saucy image and a few paragraphs on you a little more frequently, but the longer, in-depth articles I have in the hopper will probably come less frequently. If you'd like to be among the first to know when new material emanates from my dank corner of the basement, go ahead and subscribe.


text:
"James Lee Burke and Will Patton...Unbeatable!"
As a huge James Lee Burke fan, I didn't think anything could be better! And then, Will Patton was reading James Lee Burke...and things were better! I would read anything narrated by Will Patton and have read everything by James Lee Burke. Creole Belle is another terrific Dave Robicheaux book and I enjoyed every page. James Lee Burke has no equal with his descriptions, dialogue and characters. I just wish he wrote faster...
Report Inappropriate Content
If you find this review inappropriate and think it should be removed from our site, let us know. This report will be reviewed by Audible and we will take appropriate action.


text:
Software Map
Tag cloud | Project Tree | Project List | ADMS.SW meta-data
Project tree
Now limiting view to projects in the following categories:
Development Status :: 5 - Production/Stable [Remove This Filter]
Development Status > 6 - Mature
Browse By:
6 projects in result set.
|0. Website Meta Language Packaging Team - Team maintenance of Website Meta Language (WML) related packages in Debian.
|Activity Percentile: 0.00
Activity Ranking: 0.00
Registered: 2010-02-28 15:26
|1. Debian XML/SGML Group - This project is the home for a collaborative XML/SGML packaging effort for Debian.
Any Debian maintainer/developer interested in XML or SGML related tools is encouraged to join this project.
|Activity Percentile: 0.00
Activity Ranking: 0.00
Registered: 2003-10-23 20:08
|2. The Buildd Project - The autobuilder (aka buildd) tools project.
|Activity Percentile: 0.00
Activity Ranking: 0.00
Registered: 2004-08-04 07:24
|3. mod_auth_plain - Module for Apache which provides plaintext authentication.
mod_auth_plain implements authentication routines using plain text
files for apache's authentication protocol.
|Activity Percentile: 0.00
Activity Ranking: 0.00
Registered: 2003-09-24 17:00
|4. debian-user-german FAQ - This project maintains the public FAQ for debian-user-german, formerly
known as debian-user-de. The table of contents of this FAQ are sent
to the list frequently in order to help new users and keep the s/n
ratio at a proper level.
Registered: 2003-07-29 13:17
|5. Debian Cyrus IMAPd packages - Cyrus IMAPd Debian packages
Registered: 2004-12-07 14:17


text:
Valentine's Day Special: What is Love?
True love won't not allow anything to destroy a relationship. No matter what obstacles may arise, true love will always endure. Continue Reading →
True love won't not allow anything to destroy a relationship. No matter what obstacles may arise, true love will always endure. Continue Reading →
Many people feel that simply thinking well of someone is good enough and that it is unnecessary to voice how they feel. They seem to think that their partner will know automatically what they are thinking. Continue Reading →
Sometimes a long distance relationship is the only option for two people who are forced to live far apart. But unfortunately a relationship like this can be fraught with difficulties that can be stressful and even misleading. Here are five ways to help you reduce the stress of your long distance relationships. Continue Reading →
If your boyfriend has commitment phobia it's vital for you to learn about it as soon as possible. Here are 10 Questions to ask yourself about commitment phobia. Continue Reading →
If you are in the habit of apologizing too quickly then you may just have the dreaded Mea culpa syndrome. Continue Reading →
Make it too easy for a guy and he will soon lose interest. And you can't even blame him. It's human nature and it's inevitable. Continue Reading →
Unfortunately, for some people communicating on a deeper level is very difficult.They become shy about sharing the things that affect them emotionally. They cannot share their feelings. Continue Reading →


text:
Indian Valley preschoolers plant their own Garden
Indian Valley State Preschool children enjoy a garden party thanks to a grant and several supporters in the community. Photo submitted
These are a few of the stories you will find in this week's printed newspaper:
Indian Valley State Preschool children enjoy a garden party thanks to a grant and several supporters in the community. Photo submitted
Park Superintendent Darlene M. Koontz announced last week that the highway through Lassen Volcanic National Park would open for through traffic as of Friday, June 1.
"We are happy to have this major access to Lassen Volcanic National Park opened now that summer has arrived," said Koontz. "This year's road opening operations progressed more quickly compared to last year's mid-July opening primarily because of the light snowfall this past winter."Add a comment
Read more: Highway through Lassen Volcanic National Park now open
Three people were hospitalized, two with serious injuries, after being attacked by a dog Friday afternoon in Chester.
The victims' identities were not available at press time. One of the victims was the owner of the dog, according to the Plumas County Sheriff's Office.
A deputy responded to a call for "a dog bite" about 4 p.m. Sgt. Ian James arrived at the scene and found three people with injuries.Add a comment
The California Native Plant Society is hosting a Rare Plant Treasure Hunt weekend June 9 and 10 at several botanical hotspots in the Plumas National Forest near Quincy. Beginning and experienced botanists are welcome and will spend time searching for rare plants, geo-caching and photographing/documenting discoveries.Add a comment
Read more: Rare plant 'treasure hunt' offered by California Native Plant Society
National Get Outdoors Day is June 9 and Plumas National Forest Supervisor Earl Ford is extending an invitation for everyone to participate in some of the outstanding recreation opportunities in the national forest. "I encourage and invite our neighbors and community to get out and enjoy their public lands. Take some time and enjoy a healthy and active family outing by picnicking, hiking, fishing or camping, or consider participating in the volunteer trail workday."Add a comment
Read more: Plumas National Forest celebrates Get Outdoors Day


text:
06 March 2015, Rome
Marking International Women's Day 2015 (March 8th), leaders from the United Nations' three Rome-based food agencies gathered to remind the world that women farmers play a central role in achieving food and nutrition security.
Click here to continue article
39th Session of the FAO Conference
XIV World Forestry Congress
International Year of Pulses 2016
Opinion: The World Sees Progress Against Undernutrition, but it's Uneven
Statement by FAO Director-General José Graziano da Silva
International Year of Soils 2015
The FAO Awards
Mountain farming has a critical role in a post-2015 world
Preservation of soil essential for development, say panellists
FAO seeking practical experiences of implementing the Right to Food Guidelines
South-South cooperation—a crucial engine to food security and sustainable development
Opening Remarks by H.E. Mr. Anatolio Ndong Mba, Ambassador-PR of Equatorial Guinea on the Occassion of the World Food Day Celebrations
New York event on World Food Day sheds light on the importance of family farmers in attaining sustainable future
Contact us
Terms and Conditions
Scam Alert
Follow us on:


text:
Whitney Locher Theatre Credits
Whitney Locher News Feeds
Latest News on Whitney Locher
Fiasco Theatre's THE TWO GENTLEMEN OF VERONA Begins Next Month at Theatre for a New Audience (Mar 24, 2015)
Roundabout's INTO THE WOODS Enters Final Weeks Off-Broadway (Mar 17, 2015)
Into the Woods: Designer Statements (Feb 17, 2015)
[Off-Broadway, 2011]Costume Designer
New Musicals CAKE OFF and GIRLSTAR Will Premiere at Signature Theatre; Full 2015-16 Season Announced!New Video Of Cut INTO THE WOODS Song 'She'll Be Back' Performed By Traci HinesSTAGE TUBE: Tony Winner Sutton Foster on How Theatre Educators Impacted Her CareerSTAGE TUBE: First Look at Highlights of Denver Center's World Premiere of THE 12 - Terence Archie, Mike Backes, Anthony Fedorov & More!Twitter Watch: Lin-Manuel Miranda Raps for Jimmy Fallon's Outgoing Voicemail Message!BWW TV Exclusive: BREAKING DOWN THE RIFFS w/ Natalie Weiss- Back in the Habit!STAGE TUBE: Lea Salonga Sings 'I Dreamed a Dream' on SETH SPEAKS!VIDEO: Neil Patrick Harris Appears in Two New TV Spots for Heineken Light!VIDEO: Watch Sutton Foster and YOUNGER Cast Attempt 'Millenial Vocab Quiz'STAGE TUBE: Watch Highlights from La Mirada's CARRIE THE MUSICAL!STAGE TUBE: Meet the Boys of FINDING NEVERLAND!BWW TV Exclusive: Backstage with Richard Ridge- SAG Foundation Conversations Series with Stockard Channing!BWW TV: Go INTO THE WOODS to Celebrate Stephen Sondheim's 85th Birthday!STAGE TUBE: Lin-Manuel Miranda Gives Jonathan Groff a Belated Birthday Present
Message Board
NBC Sets THE WIZ as 2015 Live Musical; Broadway Revival in the Works!
Craig Zadan Offers Update On Next NBC Live Musical; Announcement Monday?
Tale As Old As Time- BEAUTY AND THE BEAST Movie Company Takes Shape; Meet the Cast!
STAGE TUBE: Watch Highlights from La Mirada's CARRIE THE MUSICAL!
Top 10 Shakespearean Insults in Honor of SOMETHING ROTTEN!


text:
I'm a Daddy and I Know It - Awesome Parody! - Comedy Videos
8-Year-Old Leaves The Judges SPEECHLESS With 'I Will Always Love You' - @keephopealive
00:05:51 20 views
Mother Who Tragically Lost Her Son Is Given Incredible Surprise - @keephopealive
00:03:04 39327 views
You Will Be In Tears When This Granddaughter Surprises Her Sick Granny At The Hospital - @keephopealive
00:05:29 5278 views
Embed keephopealive 264361 views 2012-12-28T16:09:06 This fun loving dad has his hands full with a set triplets and two older sons but he wears that badge proudly! This hysterical video parody is a tribute to all the daddies out there that love and care for their kids! We love you!
More Comedy Videos
- Spectacular Performance Of 'The Old Rugged Cross' Will Give Your Goosebumps Gooseb...Music Videos
- BibleStudyTools.com: What is unique about the Book of Genesis?-Byron YawnEducation Videos
- Easter Version of 'Hallelujah' Will Give You ChillsMusic Videos
- Talented Group Gives Irish Dance A Modern MakeoverMusic Videos
- Young Girl Turns Every Chair With Emotional Performance Of 'Power Of Love'Inspirational Videos
- 'Revelation Song' – Phillips, Craig And Dean And Kari Jobe's Breathtaking Performa...Music Videos
- He Was Because Church Sermon Illustration Mini-Movie - Oneness VideosMinistry Videos
- Chris Tomlin - Jesus Loves MeMusic Videos
- 40 Irish Dancers STUN An Entire Mall With Incredible Flash MobMusic Videos
- 'The Heart Of Worship' – Incredible Live Performance From Matt Redman At PassionMusic Videos
- Kari Jobe And Jamie Grace Come Together For Powerful Performance Of 'Hallelujah'Music Videos
- Goofy Great Dane Doesn't Want To Wake UpCute Videos
No playlists found for this account.


text:
Uno Hype - Olde English
Artist: Uno Hype
Featuring: Hassani Kwess
Producer: DJ Black Diamond
Album: F*ck The Hype EP
Avg Rating: 3.9 ( 12 votes )
Don't let the title of Uno Hype's latest EP single for you; unlike the malt liquor that shares its name, Olde English is some top-shelf sh*t—and it almost certainly won't leave you with a pounding headache tomorrow morning. Over the funky, flute-laced sample work of DJ Black Diamond, the Maryland rhymesayer trades self-assured bars with Chicago-by-way-of-D.C. rhymesayer Hassani Kwess (who recently made his solo Booth debut with Kick the Bass, Chuck). Watch for F*ck the Hype, Uno Hype's collaborative EP with Black Diamond, to hit the 'net in the near future. In the meantime, fans can click here to peep the record's official video.
Uno HypeHassani Kwess Downloads
Written by richard on 01/19/12
Submit your Rating
Reps Bombay Knox Ent.
First DJ Booth Appearance:
"Sense of Fulfillment" (2011)
You Might Like...
Commentsblog comments powered by Disqus
DJBooth TV
Discover the best new songs, videos, and albums added to the Booth.


text:
Legal eagle gains access to TV talent; TELEVISION.
DON't worry about checking out Ireland's next showbiz stars - there's a solicitor on the case.
Will Leahy takes his first ever TV presenting role in The All Ireland Talent Show: Access All Areas.
He said: "I'm still a solicitor as well as a 2FM DJ so now I will have three jobs.
"It will mean working seven days a week for six weeks but I love every job that I do and this is a new challenge for me."
Will is behind his solicitor's desk at 7.45am every day in Limerick then heads to RTE's studios at 4pm and broadcasts his 2FM show from 5pm.
He added: "I count myself very lucky to have such great opportunities."
Now every weekend he will be joining Dustin The Turkey at RTE for a behind the scenes look at the unique show.
The All Ireland Talent Show: Access All Areas begins on February 13.
DEBUT Will Leahy
Reader Opinion
|Printer friendly Cite/link Email Feedback
|Title Annotation:
|The Mirror (London, England)
|Feb 4, 2009
|Previous Article:
|My father had great love for Ireland and its people.. Son slams Haughey critics.
|Next Article:
|Flatley cure guru pumps up viewers; HEALTH.


text:
Innovation in Ireland →
Featured ▾
CEO and Co-Founder, Tamr
VP of Venture Capital, Pfizer Inc.
Chairman, CEO, & Founder, Alexandria Real Estate Equities
CEO and Founder, Techstars
Co-Founder and CEO, Wetpaint
CEO of Zero Locus
April 7, 2015 ·
San Francisco
April 8, 2015 ·
May 6, 2015 ·
Xconomy offers a number of ways to subscribe for free!
Business, life sciences, and technology news — covering Boston, Seattle, San Diego, Detroit, San Francisco, New York, Raleigh-Durham, Boulder/Denver, Texas, Wisconsin and beyond.
© 2007-2015, Xconomy, Inc.
Xconomy is a registered service mark of Xconomy, Inc.
All rights reserved.
Website development support from Andrew Koyfman with design support from Rob Hunter.


text:
There are 292 results - Show results on a map Print this page
Showing 31 - 40 of 292
A Victorian manor house located only five minutes from the town and set in peaceful surroundings. The spacious bedrooms are well furnished and decorated. Dinner can be taken in the popular adjoining M...More about Appley Manor Hotel
This 15th-century house occupies a superb location on the edge of Frensham Pond. The bedrooms are mainly spacious, and the superior, garden annexe rooms have their own patio and air conditioning. The ...More about BEST WESTERN Frensham Pond Hotel
Continuing to set high standards, this inviting hotel is best known for its high profile bistro. The individually designed bedrooms have all the Hotel du Vin signature touches including fine Egyptian ...More about Hotel du Vin Winchester
Situated deep in the heart of the New Forest and formerly a grand gentleman's residence, this charming hotel offers a relaxed and friendly environment. Bedrooms, which come in varying sizes, are smart...More about Moorhill House Hotel
The Kings Head is a traditional inn a short drive from Winchester in an idyllic quiet village. Bar and restaurant areas are smart yet cosy, and quality food is available. Rooms are exceptionally well ...More about The Kings Head
Excellent customer care is assured at this 18th-century, part-thatched house, which stands in pretty gardens in the heart of the village. Fine art and furnishings enhance the original features, and be...More about May Cottage
Dating back to the 16th century, this delightful farmhouse was gifted to Lord Nelson's family as part of the Trafalgar estate. The house has comfortable bedrooms, most with four-poster beds, and all a...More about Newton Farmhouse
Kingswood Cottage is located in Ashurst village, a quiet area just three miles from Lyndhurst yet with easy access to Southampton, which is only six miles away. Bedrooms are comfortably appointed with...More about Kingswood Cottage
Richmond House is conveniently located within a short walking distance of the town centre. Bedrooms and bathrooms are stylishly decorated and offer guests high quality comfort. All bedrooms come equip...More about Richmond House Boutique B&B
A family establishment, set in secluded grounds, that is only a short walk from Sandown's beach and high street shops. Bedrooms are very welcoming and are either on the ground or first floor. Guests c...More about The Wight Montrene


text:
Recent Meetups
February 3 · 6:30 PMFast, Reliable Queuing with PostgreSQLHappy 2015! Due to the planning for PGConf US 2015, our team has been very busy, but to make up for the lack of a January meetup, we are planning to do two in February!... Learn more
December 15, 2014 · 6:30 PMMagnus Hagander - Secure PostgreSQL DeploymentsTo escape Swedish winter for New York in December, Magnus Hagander, core PostgreSQL team member, speaker at technology conferences around the world, and avid sailor has... Learn more
December 1, 2014 · 7:00 PMAnnual NYC Tech Holiday meta-partyThe NYC PostgreSQL User Group is happy to help sponsor and support the Annual NYC Tech Group holiday party! Join around 500 members from other NYC tech groups for an... Learn more
October 1, 2014 · 6:30 PMWhat's New in PostgreSQL 9.4 - Bruce Momjian's "State of the Trunk"The release of PostgreSQL 9.4 is nigh, and to celebrate, we will be hosting NYCPUG in the historic Woolworth Building! Bruce Momjian, one of the original PostgreSQL... Learn more
September 11, 2014 · 6:30 PMAn Evening of PostgreSQL PotpourriFor this month's Meetup, we asked for multiple short talks and your fellow NYC PUG members dutifully responded. We will mix things up with a talk about Views, one about... Learn more
- See all past Meetups


text:
En Ganga Vatika Boutike Guest House todo es diáfano para que el viajero se pueda relajar. La frescura, la pureza del... Más información »
In a peaceful and clean environment guests can enjoy the stay at Tripti Cottage and relax in the quiet atmosphere... Más información »
Hotel Yog Vashishth is situated at one of the best areas in and around Sawargashram, Rishikesh, the place where the... Más información »
Beautiful moments have the most formidable rejuvenating power not only when they are happening, but all through the... Más información »
Set in Rishikesh City, Hotel the Holiday Home is located on the banks of the River Ganges. It offers Wi-Fi, a 24-hour... Más información »
Home Away Home. The guest house is situated at across the river in Swargashram Area, which is apx. 12 km. by motor... Más información »


text:
Pronunciation: 五言律詩
Added on: 2012-03-21 Listened: 2 timesin: noun
Pronunciation in Japanese [ja]
- Pronunciation by halcan (Female from Japan)
0 votes
Could you do it better? different accent? Pronounce 五言律詩 in Japanese
Accents & languages on maps
- Random word: 経営難に陥る
by Yandex Translate English translation:
五言律詩 = V statement of legal poetry.
Not satisfied?
Modify word:
· Add languages
· Add categories
Report word:
Is there anything wrong with this word?
Please report it here.


text:
PLOS Biology: New Articles PLOS http://www.plosbiology.org/ firstname.lastname@example.com Publishing science info:doi/10.1371/feed.pbio This work is licensed under a Creative Commons Attribution-Share Alike 3.0 License http://www.plosbiology.org/${webserver-url}images/favicon.ico http://www.plosbiology.org/${webserver-url}images/favicon.ico 2015-04-01T03:06:05Z Subscribe with My Yahoo!Subscribe with NewsGatorSubscribe with My AOLSubscribe with BloglinesSubscribe with NetvibesSubscribe with GoogleSubscribe with Pageflakes Integration of Shallow Gradients of Shh and Netrin-1 Guides Commissural Axons Tyler F. W. Sloan et al. info:doi/10.1371/journal.pbio.1002119 2015-03-31T21:00:00Z 2015-03-31T21:00:00Z
by Tyler F. W. Sloan, Mohammad A. Qasaimeh, David Juncker, Patricia T. Yam, Frédéric Charron
 During nervous system development, gradients of Sonic Hedgehog (Shh) and Netrin-1 attract growth cones of commissural axons toward the floor plate of the embryonic spinal cord. Mice defective for either Shh or Netrin-1 signaling have commissural axon guidance defects, suggesting that both Shh and Netrin-1 are required for correct axon guidance. However, how Shh and Netrin-1 collaborate to guide axons is not known. We first quantified the steepness of the Shh gradient in the spinal cord and found that it is mostly very shallow. We then developed an in vitro microfluidic guidance assay to simulate these shallow gradients. We found that axons of dissociated commissural neurons respond to steep but not shallow gradients of Shh or Netrin-1. However, when we presented axons with combined Shh and Netrin-1 gradients, they had heightened sensitivity to the guidance cues, turning in response to shallower gradients that were unable to guide axons when only one cue was present. Furthermore, these shallow gradients polarized growth cone Src-family kinase (SFK) activity only when Shh and Netrin-1 were combined, indicating that SFKs can integrate the two guidance cues. Together, our results indicate that Shh and Netrin-1 synergize to enable growth cones to sense shallow gradients in regions of the spinal cord where the steepness of a single guidance cue is insufficient to guide axons, and we identify a novel type of synergy that occurs when the steepness (and not the concentration) of a guidance cue is limiting. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002119 A Voltage-Gated Calcium Channel Regulates Lysosomal Fusion with Endosomes and Autophagosomes and Is Required for Neuronal Homeostasis Xuejun Tian et al. info:doi/10.1371/journal.pbio.1002103 2015-03-26T21:00:00Z 2015-03-26T21:00:00Z
by Xuejun Tian, Upasana Gala, Yongping Zhang, Weina Shang, Sonal Nagarkar Jaiswal, Alberto di Ronza, Manish Jaiswal, Shinya Yamamoto, Hector Sandoval, Lita Duraine, Marco Sardiello, Roy V. Sillitoe, Kartik Venkatachalam, Hengyu Fan, Hugo J. Bellen, Chao Tong
 Autophagy helps deliver sequestered intracellular cargo to lysosomes for proteolytic degradation and thereby maintains cellular homeostasis by preventing accumulation of toxic substances in cells. In a forward mosaic screen in Drosophila designed to identify genes required for neuronal function and maintenance, we identified multiple cacophony (cac) mutant alleles. They exhibit an age-dependent accumulation of autophagic vacuoles (AVs) in photoreceptor terminals and eventually a degeneration of the terminals and surrounding glia. cac encodes an α1 subunit of a Drosophila voltage-gated calcium channel (VGCC) that is required for synaptic vesicle fusion with the plasma membrane and neurotransmitter release. Here, we show that cac mutant photoreceptor terminals accumulate AV-lysosomal fusion intermediates, suggesting that Cac is necessary for the fusion of AVs with lysosomes, a poorly defined process. Loss of another subunit of the VGCC, α2δ or straightjacket (stj), causes phenotypes very similar to those caused by the loss of cac, indicating that the VGCC is required for AV-lysosomal fusion. The role of VGCC in AV-lysosomal fusion is evolutionarily conserved, as the loss of the mouse homologues, Cacna1a and Cacna2d2, also leads to autophagic defects in mice. Moreover, we find that CACNA1A is localized to the lysosomes and that loss of lysosomal Cacna1a in cerebellar cultured neurons leads to a failure of lysosomes to fuse with endosomes and autophagosomes. Finally, we show that the lysosomal CACNA1A but not the plasma-membrane resident CACNA1A is required for lysosomal fusion. In summary, we present a model in which the VGCC plays a role in autophagy by regulating the fusion of AVs with lysosomes through its calcium channel activity and hence functions in maintaining neuronal homeostasis. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002103 The Polarity Protein Scribble Regulates Myelination and Remyelination in the Central Nervous System Andrew A. Jarjour et al. info:doi/10.1371/journal.pbio.1002107 2015-03-25T21:00:00Z 2015-03-25T21:00:00Z
by Andrew A. Jarjour, Amanda Boyd, Lukas E. Dow, Rebecca K. Holloway, Sandra Goebbels, Patrick O. Humbert, Anna Williams, Charles ffrench-Constant
 The development and regeneration of myelin by oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), requires profound changes in cell shape that lead to myelin sheath initiation and formation. Here, we demonstrate a requirement for the basal polarity complex protein Scribble in CNS myelination and remyelination. Scribble is expressed throughout oligodendroglial development and is up-regulated in mature oligodendrocytes where it is localised to both developing and mature CNS myelin sheaths. Knockdown of Scribble expression in cultured oligodendroglia results in disrupted morphology and myelination initiation. When Scribble expression is conditionally eliminated in the myelinating glia of transgenic mice, myelin initiation in CNS is disrupted, both during development and following focal demyelination, and longitudinal extension of the myelin sheath is disrupted. At later stages of myelination, Scribble acts to negatively regulate myelin thickness whilst suppressing the extracellular signal-related kinase (ERK)/mitogen-activated protein kinase (MAP) kinase pathway, and localises to non-compact myelin flanking the node of Ranvier where it is required for paranodal axo-glial adhesion. These findings demonstrate an essential role for the evolutionarily-conserved regulators of intracellular polarity in myelination and remyelination. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002107 A Biotic Game Design Project for Integrated Life Science and Engineering Education Nate J. Cira et al. info:doi/10.1371/journal.pbio.1002110 2015-03-25T21:00:00Z 2015-03-25T21:00:00Z
by Nate J. Cira, Alice M. Chung, Aleksandra K. Denisin, Stefano Rensi, Gabriel N. Sanchez, Stephen R. Quake, Ingmar H. Riedel-Kruse
 Engaging, hands-on design experiences are key for formal and informal Science, Technology, Engineering, and Mathematics (STEM) education. Robotic and video game design challenges have been particularly effective in stimulating student interest, but equivalent experiences for the life sciences are not as developed. Here we present the concept of a "biotic game design project" to motivate student learning at the interface of life sciences and device engineering (as part of a cornerstone bioengineering devices course). We provide all course material and also present efforts in adapting the project's complexity to serve other time frames, age groups, learning focuses, and budgets. Students self-reported that they found the biotic game project fun and motivating, resulting in increased effort. Hence this type of design project could generate excitement and educational impact similar to robotics and video games. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002110 Relatedness, Conflict, and the Evolution of Eusociality Xiaoyun Liao et al. info:doi/10.1371/journal.pbio.1002098 2015-03-23T21:00:00Z 2015-03-23T21:00:00Z
by Xiaoyun Liao, Stephen Rong, David C. Queller
 The evolution of sterile worker castes in eusocial insects was a major problem in evolutionary theory until Hamilton developed a method called inclusive fitness. He used it to show that sterile castes could evolve via kin selection, in which a gene for altruistic sterility is favored when the altruism sufficiently benefits relatives carrying the gene. Inclusive fitness theory is well supported empirically and has been applied to many other areas, but a recent paper argued that the general method of inclusive fitness was wrong and advocated an alternative population genetic method. The claim of these authors was bolstered by a new model of the evolution of eusociality with novel conclusions that appeared to overturn some major results from inclusive fitness. Here we report an expanded examination of this kind of model for the evolution of eusociality and show that all three of its apparently novel conclusions are essentially false. Contrary to their claims, genetic relatedness is important and causal, workers are agents that can evolve to be in conflict with the queen, and eusociality is not so difficult to evolve. The misleading conclusions all resulted not from incorrect math but from overgeneralizing from narrow assumptions or parameter values. For example, all of their models implicitly assumed high relatedness, but modifying the model to allow lower relatedness shows that relatedness is essential and causal in the evolution of eusociality. Their modeling strategy, properly applied, actually confirms major insights of inclusive fitness studies of kin selection. This broad agreement of different models shows that social evolution theory, rather than being in turmoil, is supported by multiple theoretical approaches. It also suggests that extensive prior work using inclusive fitness, from microbial interactions to human evolution, should be considered robust unless shown otherwise. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002098 Open Labware: 3-D Printing Your Own Lab Equipment Tom Baden et al. info:doi/10.1371/journal.pbio.1002086 2015-03-20T21:00:00Z 2015-03-20T21:00:00Z
by Tom Baden, Andre Maia Chagas, Greg Gage, Timothy Marzullo, Lucia L. Prieto-Godino, Thomas Euler
 The introduction of affordable, consumer-oriented 3-D printers is a milestone in the current "maker movement," which has been heralded as the next industrial revolution. Combined with free and open sharing of detailed design blueprints and accessible development tools, rapid prototypes of complex products can now be assembled in one's own garage—a game-changer reminiscent of the early days of personal computing. At the same time, 3-D printing has also allowed the scientific and engineering community to build the "little things" that help a lab get up and running much faster and easier than ever before. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002086 Correction: A Bioenergetic Basis for Membrane Divergence in Archaea and Bacteria The PLOS Biology Staff info:doi/10.1371/journal.pbio.1002102 2015-03-20T21:00:00Z 2015-03-20T21:00:00Z
by The PLOS Biology Staff
 http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002102 Coadaptation between Mother and Offspring: Why Not? Jason B. Wolf et al. info:doi/10.1371/journal.pbio.1002085 2015-03-18T21:00:00Z 2015-03-18T21:00:00Z
by Jason B. Wolf, Michael Cowley, Andrew Ward
 http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002085 Mother and Offspring in Conflict: Why Not? Francisco Úbeda et al. info:doi/10.1371/journal.pbio.1002084 2015-03-18T21:00:00Z 2015-03-18T21:00:00Z
by Francisco Úbeda, Andy Gardner
 http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002084 Cell Cycle–Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas Yung Hae Kim et al. info:doi/10.1371/journal.pbio.1002111 2015-03-18T21:00:00Z 2015-03-18T21:00:00Z
by Yung Hae Kim, Hjalte List Larsen, Pau Rué, Laurence A. Lemaire, Jorge Ferrer, Anne Grapin-Botton
 Organogenesis relies on the spatiotemporal balancing of differentiation and proliferation driven by an expanding pool of progenitor cells. In the mouse pancreas, lineage tracing at the population level has shown that the expanding pancreas progenitors can initially give rise to all endocrine, ductal, and acinar cells but become bipotent by embryonic day 13.5, giving rise to endocrine cells and ductal cells. However, the dynamics of individual progenitors balancing self-renewal and lineage-specific differentiation has never been described. Using three-dimensional live imaging and in vivo clonal analysis, we reveal the contribution of individual cells to the global behaviour and demonstrate three modes of progenitor divisions: symmetric renewing, symmetric endocrinogenic, and asymmetric generating a progenitor and an endocrine progenitor. Quantitative analysis shows that the endocrine differentiation process is consistent with a simple model of cell cycle–dependent stochastic priming of progenitors to endocrine fate. The findings provide insights to define control parameters to optimize the generation of β-cells in vitro. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002111 Viral Cell-to-Cell Transmission—Why Less Is More Lauren A. Richardson info:doi/10.1371/journal.pbio.1002095 2015-03-17T21:00:00Z 2015-03-17T21:00:00Z
by Lauren A. Richardson
 http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002095 Viruses Roll the Dice: The Stochastic Behavior of Viral Genome Molecules Accelerates Viral Adaptation at the Cell and Tissue Levels Shuhei Miyashita et al. info:doi/10.1371/journal.pbio.1002094 2015-03-17T21:00:00Z 2015-03-17T21:00:00Z
by Shuhei Miyashita, Kazuhiro Ishibashi, Hirohisa Kishino, Masayuki Ishikawa
 Recent studies on evolutionarily distant viral groups have shown that the number of viral genomes that establish cell infection after cell-to-cell transmission is unexpectedly small (1–20 genomes). This aspect of viral infection appears to be important for the adaptation and survival of viruses. To clarify how the number of viral genomes that establish cell infection is determined, we developed a simulation model of cell infection for tomato mosaic virus (ToMV), a positive-strand RNA virus. The model showed that stochastic processes that govern the replication or degradation of individual genomes result in the infection by a small number of genomes, while a large number of infectious genomes are introduced in the cell. It also predicted two interesting characteristics regarding cell infection patterns: stochastic variation among cells in the number of viral genomes that establish infection and stochastic inequality in the accumulation of their progenies in each cell. Both characteristics were validated experimentally by inoculating tobacco cells with a library of nucleotide sequence–tagged ToMV and analyzing the viral genomes that accumulated in each cell using a high-throughput sequencer. An additional simulation model revealed that these two characteristics enhance selection during tissue infection. The cell infection model also predicted a mechanism that enhances selection at the cellular level: a small difference in the replication abilities of coinfected variants results in a large difference in individual accumulation via the multiple-round formation of the replication complex (i.e., the replication machinery). Importantly, this predicted effect was observed in vivo. The cell infection model was robust to changes in the parameter values, suggesting that other viruses could adopt similar adaptation mechanisms. Taken together, these data reveal a comprehensive picture of viral infection processes including replication, cell-to-cell transmission, and evolution, which are based on the stochastic behavior of the viral genome molecules in each cell. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002094 The Extent and Consequences of P-Hacking in Science Megan L. Head et al. info:doi/10.1371/journal.pbio.1002106 2015-03-13T21:00:00Z 2015-03-13T21:00:00Z
by Megan L. Head, Luke Holman, Rob Lanfear, Andrew T. Kahn, Michael D. Jennions
 A focus on novel, confirmatory, and statistically significant results leads to substantial bias in the scientific literature. One type of bias, known as "p-hacking," occurs when researchers collect or select data or statistical analyses until nonsignificant results become significant. Here, we use text-mining to demonstrate that p-hacking is widespread throughout science. We then illustrate how one can test for p-hacking when performing a meta-analysis and show that, while p-hacking is probably common, its effect seems to be weak relative to the real effect sizes being measured. This result suggests that p-hacking probably does not drastically alter scientific consensuses drawn from meta-analyses. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002106 Link between Cell Junctions and Microtubule Cytoskeleton Is Critical for Epithelial Morphogenesis Richard Robinson info:doi/10.1371/journal.pbio.1002088 2015-03-12T21:00:00Z 2015-03-12T21:00:00Z
by Richard Robinson
 http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002088 Alpha-catenin-Dependent Recruitment of the Centrosomal Protein CAP350 to Adherens Junctions Allows Epithelial Cells to Acquire a Columnar Shape Maria P. Gavilan et al. info:doi/10.1371/journal.pbio.1002087 2015-03-12T21:00:00Z 2015-03-12T21:00:00Z
by Maria P. Gavilan, Marina Arjona, Angel Zurbano, Etienne Formstecher, Juan R. Martinez-Morales, Michel Bornens, Rosa M. Rios
 Epithelial morphogenesis involves a dramatic reorganisation of the microtubule cytoskeleton. How this complex process is controlled at the molecular level is still largely unknown. Here, we report that the centrosomal microtubule (MT)-binding protein CAP350 localises at adherens junctions in epithelial cells. By two-hybrid screening, we identified a direct interaction of CAP350 with the adhesion protein α-catenin that was further confirmed by co-immunoprecipitation experiments. Block of epithelial cadherin (E-cadherin)-mediated cell-cell adhesion or α-catenin depletion prevented CAP350 localisation at cell-cell junctions. Knocking down junction-located CAP350 inhibited the establishment of an apico-basal array of microtubules and impaired the acquisition of columnar shape in Madin-Darby canine kidney II (MDCKII) cells grown as polarised epithelia. Furthermore, MDCKII cystogenesis was also defective in junctional CAP350-depleted cells. CAP350-depleted MDCKII cysts were smaller and contained either multiple lumens or no lumen. Membrane polarity was not affected, but cortical microtubule bundles did not properly form. Our results indicate that CAP350 may act as an adaptor between adherens junctions and microtubules, thus regulating epithelial differentiation and contributing to the definition of cell architecture. We also uncover a central role of α-catenin in global cytoskeleton remodelling, in which it acts not only on actin but also on MT reorganisation during epithelial morphogenesis. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002087 ATPase-Dependent Control of the Mms21 SUMO Ligase during DNA Repair Marcelino Bermúdez-López et al. info:doi/10.1371/journal.pbio.1002089 2015-03-12T21:00:00Z 2015-03-12T21:00:00Z
by Marcelino Bermúdez-López, Irene Pociño-Merino, Humberto Sánchez, Andrés Bueno, Clàudia Guasch, Seba Almedawar, Sergi Bru-Virgili, Eloi Garí, Claire Wyman, David Reverter, Neus Colomina, Jordi Torres-Rosell
 Modification of proteins by SUMO is essential for the maintenance of genome integrity. During DNA replication, the Mms21-branch of the SUMO pathway counteracts recombination intermediates at damaged replication forks, thus facilitating sister chromatid disjunction. The Mms21 SUMO ligase docks to the arm region of the Smc5 protein in the Smc5/6 complex; together, they cooperate during recombinational DNA repair. Yet how the activity of the SUMO ligase is controlled remains unknown. Here we show that the SUMO ligase and the chromosome disjunction functions of Mms21 depend on its docking to an intact and active Smc5/6 complex, indicating that the Smc5/6-Mms21 complex operates as a large SUMO ligase in vivo. In spite of the physical distance separating the E3 and the nucleotide-binding domains in Smc5/6, Mms21-dependent sumoylation requires binding of ATP to Smc5, a step that is part of the ligase mechanism that assists Ubc9 function. The communication is enabled by the presence of a conserved disruption in the coiled coil domain of Smc5, pointing to potential conformational changes for SUMO ligase activation. In accordance, scanning force microscopy of the Smc5-Mms21 heterodimer shows that the molecule is physically remodeled in an ATP-dependent manner. Our results demonstrate that the ATP-binding activity of the Smc5/6 complex is coordinated with its SUMO ligase, through the coiled coil domain of Smc5 and the physical remodeling of the molecule, to promote sumoylation and chromosome disjunction during DNA repair. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002089 Biodiversity Governance: A Tower of Babel of Scales and Cultures Jorge Soberón et al. info:doi/10.1371/journal.pbio.1002108 2015-03-12T21:00:00Z 2015-03-12T21:00:00Z
by Jorge Soberón, A. Townsend Peterson
 The recently created Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES), originally focused on multilateral and global issues, is shifting its focus to address local issues and to include in its assessments local stakeholders and indigenous and traditional systems of knowledge. Acknowledging that full biodiversity governance is unavoidably rooted in participation of local actors and their problems and knowledge, we suggest that to deal successfully with the complexity and diversity of local issues, including indigenous knowledge systems, IPBES must recognize a key role of local institutions. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002108 Bistability in a Metabolic Network Underpins the De Novo Evolution of Colony Switching in Pseudomonas fluorescens Jenna Gallie et al. info:doi/10.1371/journal.pbio.1002109 2015-03-12T21:00:00Z 2015-03-12T21:00:00Z
by Jenna Gallie, Eric Libby, Frederic Bertels, Philippe Remigi, Christian B. Jendresen, Gayle C. Ferguson, Nicolas Desprat, Marieke F. Buffing, Uwe Sauer, Hubertus J. E. Beaumont, Jan Martinussen, Mogens Kilstrup, Paul B. Rainey
 Phenotype switching is commonly observed in nature. This prevalence has allowed the elucidation of a number of underlying molecular mechanisms. However, little is known about how phenotypic switches arise and function in their early evolutionary stages. The first opportunity to provide empirical insight was delivered by an experiment in which populations of the bacterium Pseudomonas fluorescens SBW25 evolved, de novo, the ability to switch between two colony phenotypes. Here we unravel the molecular mechanism behind colony switching, revealing how a single nucleotide change in a gene enmeshed in central metabolism (carB) generates such a striking phenotype. We show that colony switching is underpinned by ON/OFF expression of capsules consisting of a colanic acid-like polymer. We use molecular genetics, biochemical analyses, and experimental evolution to establish that capsule switching results from perturbation of the pyrimidine biosynthetic pathway. Of central importance is a bifurcation point at which uracil triphosphate is partitioned towards either nucleotide metabolism or polymer production. This bifurcation marks a cell-fate decision point whereby cells with relatively high pyrimidine levels favour nucleotide metabolism (capsule OFF), while cells with lower pyrimidine levels divert resources towards polymer biosynthesis (capsule ON). This decision point is present and functional in the wild-type strain. Finally, we present a simple mathematical model demonstrating that the molecular components of the decision point are capable of producing switching. Despite its simple mutational cause, the connection between genotype and phenotype is complex and multidimensional, offering a rare glimpse of how noise in regulatory networks can provide opportunity for evolution. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002109 A Neural Mechanism for Time-Window Separation Resolves Ambiguity of Adaptive Coding K. Jannis Hildebrandt et al. info:doi/10.1371/journal.pbio.1002096 2015-03-11T21:00:00Z 2015-03-11T21:00:00Z
by K. Jannis Hildebrandt, Bernhard Ronacher, R. Matthias Hennig, Jan Benda
 The senses of animals are confronted with changing environments and different contexts. Neural adaptation is one important tool to adjust sensitivity to varying intensity ranges. For instance, in a quiet night outdoors, our hearing is more sensitive than when we are confronted with the plurality of sounds in a large city during the day. However, adaptation also removes available information on absolute sound levels and may thus cause ambiguity. Experimental data on the trade-off between benefits and loss through adaptation is scarce and very few mechanisms have been proposed to resolve it. We present an example where adaptation is beneficial for one task—namely, the reliable encoding of the pattern of an acoustic signal—but detrimental for another—the localization of the same acoustic stimulus. With a combination of neurophysiological data, modeling, and behavioral tests, we show that adaptation in the periphery of the auditory pathway of grasshoppers enables intensity-invariant coding of amplitude modulations, but at the same time, degrades information available for sound localization. We demonstrate how focusing the response of localization neurons to the onset of relevant signals separates processing of localization and pattern information temporally. In this way, the ambiguity of adaptive coding can be circumvented and both absolute and relative levels can be processed using the same set of peripheral neurons. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002096 Correction: Dynamic Grouping of Hippocampal Neural Activity During Cognitive Control of Two Spatial Frames The PLOS Biology Staff info:doi/10.1371/journal.pbio.1002100 2015-03-11T21:00:00Z 2015-03-11T21:00:00Z
by The PLOS Biology Staff
 http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002100 Committing to Place: The Potential of Open Collaborations for Trusted Environmental Governance Claire Waterton et al. info:doi/10.1371/journal.pbio.1002081 2015-03-05T22:00:00Z 2015-03-05T22:00:00Z
by Claire Waterton, Stephen C. Maberly, Judith Tsouvalis, Nigel Watson, Ian J. Winfield, Lisa R. Norton
 Conventional modes of environmental governance, which typically exclude those stakeholders that are most directly linked to the specific place, frequently fail to have the desired impact. Using the example of lake water management in Loweswater, a small hamlet within the English Lake District, we consider the ways in which new "collectives" for local, bottom-up governance of water bodies can reframe problems in ways which both bind lay and professional people to place, and also recast the meaning of "solutions" in thought-provoking ways. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002081 Correction: A New Framework for Cortico-Striatal Plasticity: Behavioural Theory Meets In Vitro Data at the Reinforcement-Action Interface The PLOS Biology Staff info:doi/10.1371/journal.pbio.1002099 2015-03-05T22:00:00Z 2015-03-05T22:00:00Z
by The PLOS Biology Staff
 http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002099 Correction: Self-Renewal of Single Mouse Hematopoietic Stem Cells Is Reduced by JAK2V617F Without Compromising Progenitor Cell Expansion The PLOS Biology Staff info:doi/10.1371/journal.pbio.1002092 2015-03-04T22:00:00Z 2015-03-04T22:00:00Z
by The PLOS Biology Staff
 http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002092 A Novel Bipartite Centrosome Coordinates the Apicomplexan Cell Cycle Elena S. Suvorova et al. info:doi/10.1371/journal.pbio.1002093 2015-03-03T22:00:00Z 2015-03-03T22:00:00Z
by Elena S. Suvorova, Maria Francia, Boris Striepen, Michael W. White
 Apicomplexan parasites can change fundamental features of cell division during their life cycles, suspending cytokinesis when needed and changing proliferative scale in different hosts and tissues. The structural and molecular basis for this remarkable cell cycle flexibility is not fully understood, although the centrosome serves a key role in determining when and how much replication will occur. Here we describe the discovery of multiple replicating core complexes with distinct protein composition and function in the centrosome of Toxoplasma gondii. An outer core complex distal from the nucleus contains the TgCentrin1/TgSfi1 protein pair, along with the cartwheel protein TgSas-6 and a novel Aurora-related kinase, while an inner core closely aligned with the unique spindle pole (centrocone) holds distant orthologs of the CEP250/C-Nap protein family. This outer/inner spatial relationship of centrosome cores is maintained throughout the cell cycle. When in metaphase, the duplicated cores align to opposite sides of the kinetochores in a linear array. As parasites transition into S phase, the cores sequentially duplicate, outer core first and inner core second, ensuring that each daughter parasite inherits one copy of each type of centrosome core. A key serine/threonine kinase distantly related to the MAPK family is localized to the centrosome, where it restricts core duplication to once per cycle and ensures the proper formation of new daughter parasites. Genetic analysis of the outer core in a temperature-sensitive mutant demonstrated this core functions primarily in cytokinesis. An inhibition of ts-TgSfi1 function at high temperature caused the loss of outer cores and a severe block to budding, while at the same time the inner core amplified along with the unique spindle pole, indicating the inner core and spindle pole are independent and co-regulated. The discovery of a novel bipartite organization in the parasite centrosome that segregates the functions of karyokinesis and cytokinesis provides an explanation for how cell cycle flexibility is achieved in apicomplexan life cycles. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002093 Estimating the Life Course of Influenza A(H3N2) Antibody Responses from Cross-Sectional Data Adam J. Kucharski et al. info:doi/10.1371/journal.pbio.1002082 2015-03-03T22:00:00Z 2015-03-03T22:00:00Z
by Adam J. Kucharski, Justin Lessler, Jonathan M. Read, Huachen Zhu, Chao Qiang Jiang, Yi Guan, Derek A. T. Cummings, Steven Riley
 The immunity of a host population against specific influenza A strains can influence a number of important biological processes, from the emergence of new virus strains to the effectiveness of vaccination programmes. However, the development of an individual's long-lived antibody response to influenza A over the course of a lifetime remains poorly understood. Accurately describing this immunological process requires a fundamental understanding of how the mechanisms of boosting and cross-reactivity respond to repeated infections. Establishing the contribution of such mechanisms to antibody titres remains challenging because the aggregate effect of immune responses over a lifetime are rarely observed directly. To uncover the aggregate effect of multiple influenza infections, we developed a mechanistic model capturing both past infections and subsequent antibody responses. We estimated parameters of the model using cross-sectional antibody titres to nine different strains spanning 40 years of circulation of influenza A(H3N2) in southern China. We found that "antigenic seniority" and quickly decaying cross-reactivity were important components of the immune response, suggesting that the order in which individuals were infected with influenza strains shaped observed neutralisation titres to a particular virus. We also obtained estimates of the frequency and age distribution of influenza infection, which indicate that although infections became less frequent as individuals progressed through childhood and young adulthood, they occurred at similar rates for individuals above age 30 y. By establishing what are likely to be important mechanisms driving epochal trends in population immunity, we also identified key directions for future studies. In particular, our results highlight the need for longitudinal samples that are tested against multiple historical strains. This could lead to a better understanding of how, over the course of a lifetime, fast, transient antibody dynamics combine with the longer-term immune responses considered here. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002082 Cofilin1 Controls Transcolumnar Plasticity in Dendritic Spines in Adult Barrel Cortex Tadashi Tsubota et al. info:doi/10.1371/journal.pbio.1002070 2015-02-27T22:00:00Z 2015-02-27T22:00:00Z
by Tadashi Tsubota, Reiko Okubo-Suzuki, Yohei Ohashi, Keita Tamura, Koshin Ogata, Masae Yaguchi, Makoto Matsuyama, Kaoru Inokuchi, Yasushi Miyashita
 During sensory deprivation, the barrel cortex undergoes expansion of a functional column representing spared inputs (spared column), into the neighboring deprived columns (representing deprived inputs) which are in turn shrunk. As a result, the neurons in a deprived column simultaneously increase and decrease their responses to spared and deprived inputs, respectively. Previous studies revealed that dendritic spines are remodeled during this barrel map plasticity. Because cofilin1, a predominant regulator of actin filament turnover, governs both the expansion and shrinkage of the dendritic spine structure in vitro, it hypothetically regulates both responses in barrel map plasticity. However, this hypothesis remains untested. Using lentiviral vectors, we knocked down cofilin1 locally within layer 2/3 neurons in a deprived column. Cofilin1-knocked-down neurons were optogenetically labeled using channelrhodopsin-2, and electrophysiological recordings were targeted to these knocked-down neurons. We showed that cofilin1 knockdown impaired response increases to spared inputs but preserved response decreases to deprived inputs, indicating that cofilin1 dependency is dissociated in these two types of barrel map plasticity. To explore the structural basis of this dissociation, we then analyzed spine densities on deprived column dendritic branches, which were supposed to receive dense horizontal transcolumnar projections from the spared column. We found that spine number increased in a cofilin1-dependent manner selectively in the distal part of the supragranular layer, where most of the transcolumnar projections existed. Our findings suggest that cofilin1-mediated actin dynamics regulate functional map plasticity in an input-specific manner through the dendritic spine remodeling that occurs in the horizontal transcolumnar circuits. These new mechanistic insights into transcolumnar plasticity in adult rats may have a general significance for understanding reorganization of neocortical circuits that have more sophisticated columnar organization than the rodent neocortex, such as the primate neocortex. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002070 PLOS Biology 2014 Reviewer Thank You info:doi/10.1371/journal.pbio.1002101 2015-02-27T22:00:00Z 2015-02-27T22:00:00Z  http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002101 Correction: Amassing Efforts against Alien Invasive Species in Europe The PLOS Biology Staff info:doi/10.1371/journal.pbio.1002090 2015-02-26T22:00:00Z 2015-02-26T22:00:00Z
by The PLOS Biology Staff
 http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002090 Multisensory Causal Inference in the Brain Christoph Kayser et al. info:doi/10.1371/journal.pbio.1002075 2015-02-24T22:00:00Z 2015-02-24T22:00:00Z
by Christoph Kayser, Ladan Shams
 At any given moment, our brain processes multiple inputs from its different sensory modalities (vision, hearing, touch, etc.). In deciphering this array of sensory information, the brain has to solve two problems: (1) which of the inputs originate from the same object and should be integrated and (2) for the sensations originating from the same object, how best to integrate them. Recent behavioural studies suggest that the human brain solves these problems using optimal probabilistic inference, known as Bayesian causal inference. However, how and where the underlying computations are carried out in the brain have remained unknown. By combining neuroimaging-based decoding techniques and computational modelling of behavioural data, a new study now sheds light on how multisensory causal inference maps onto specific brain areas. The results suggest that the complexity of neural computations increases along the visual hierarchy and link specific components of the causal inference process with specific visual and parietal regions. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002075 Walk on the Wild Side: Estimating the Global Magnitude of Visits to Protected Areas Andrew Balmford et al. info:doi/10.1371/journal.pbio.1002074 2015-02-24T22:00:00Z 2015-02-24T22:00:00Z
by Andrew Balmford, Jonathan M. H. Green, Michael Anderson, James Beresford, Charles Huang, Robin Naidoo, Matt Walpole, Andrea Manica
 How often do people visit the world's protected areas (PAs)? Despite PAs covering one-eighth of the land and being a major focus of nature-based recreation and tourism, we don't know. To address this, we compiled a globally-representative database of visits to PAs and built region-specific models predicting visit rates from PA size, local population size, remoteness, natural attractiveness, and national income. Applying these models to all but the very smallest of the world's terrestrial PAs suggests that together they receive roughly 8 billion (8 x 109) visits/y—of which more than 80% are in Europe and North America. Linking our region-specific visit estimates to valuation studies indicates that these visits generate approximately US $600 billion/y in direct in-country expenditure and US $250 billion/y in consumer surplus. These figures dwarf current, typically inadequate spending on conserving PAs. Thus, even without considering the many other ecosystem services that PAs provide to people, our findings underscore calls for greatly increased investment in their conservation. http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1002074


text:
Good place to stop for a night but be prepared for a very small room. We stayed here because we had our little pooch with us. We requested a king bed which we did get but the bed took up most of the room. There was not a chair to sit in and the bathroom was tiny.
The bed was comfy and the staff was nice. Breakfast was typical. The hotel is in the middle of a shopping mall/ strip. Restaurants are all over and it is not far from the town which is adorable b.
- Official Description (provided by the hotel):
- Two story interior corridor hotel featuring rooms with two double beds or one King size bed. Hotel offers free hot breakfast, High speed wireless internet access, free parking, business center. Each room has a coffee maker, iron and ironing board , refrigerator and microwave. 24 Coffee available. Within walking distance to restaurants and shopping. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Travelocity, Expedia, Carlson, Booking.com, Orbitz, Priceline, Hotels.com, Odigeo, TripOnline SA and Tingo so you can book your Country Inn & Suites By Carlson Frederick reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Holiday Inn Express Frederick Hotel Frederick
- Holiday Inn Frederick


text:
Release Date:
January 19, 2010
Based on a true story, the two-part TV movie I Know My First Name Is Steven tells the tragic story of Steven Stayner. At age seven, Steven was kidnapped by two men who held him captive in a tiny shed for seven years. One of the men, a habitual child abuser named Kenneth Parnell, sexually assaulted Steven on an almost daily basis during the boy's ordeal. At age 14, Steven finally was able to escape and return to his family. But we are shown that Steven's safe return was far from the happy ending it appeared to be. He's forced to adjust to a family he'd never really known, to convince himself that his parents had never forgotten him, and to put his seven-year hell behind him. While I Know My First Name Is Steven ends on an upbeat note, the real Stayner died in a motorcycle accident only a few months after this film was first telecast in May 1989. ~ Hal Erickson, Rovi
- Genre: Drama
- Category Psychological Drama, Crime Drama, Docudrama
- Theme: Kidnapping, Haunted By the Past
- Run Time: 03 hr 05 min
- Language: English
- Picture Format: pan_and_scan
- Lead Actor: Arliss Howard , Luke Edwards , Cindy Pickett , John Ashton , Ray Walston
- Supporting Actor: Pamela McMyler , Lyla Graham , Jonathan Perpich , John Vickery , Jason Presson , James Ingersoll , Jacob Gelman , Harold Pruett , Gregg Henry , Darcy de Moss , Corin Nemec , Bryan Cranston , Stephen Dorff , Wendy Gordon , Vance Valencia , Scott Reeves , Natividad Vacio , John de Mita , Andrew Amador , Robina Suwol , Shane McCabe , William Frankfather , Whitney Rydbeck , David C. Glasser , Al Berry , Amy O'Neill , Barry Corbin , Peter Michael Goetz , Todd Eric Andrews , Beth Grant , Tiiu Leek , Dave Adams , Kim Maxwell , Michael Chieffo , Raymond Cruz , Robert Balderson , Stephanie Walski , Shannon Holt , Karl Wiedergott , Jeff Olson , Gregory Mars Martin , Brenda Hillhouse , Barbara Tarbuck , Annie O'Donnell , Scott Curtis , Alan Fudge , Allison Mack , Cassy Friel , June C. Ellis , Dennis Fimple
- Director: Larry Elikann
other Info.
- Online Item #: 13449357
- Store Item Number (DPCI): 246-06-6663
- Made in the USA or Imported


text:
Building a new pool...Kool Deck, Stained Concrete..what??
We're building our first pool, finally. It's only been a week and I'm already worn out LOL. I'll post pics as soon as I figure this out..Supposed to get gunite tomorrow, but it's supposed to flood tomorrow, so I guess no gunite for us. We're not building a huge or elaborate pool but one that's perfect for the value of our home and the age of our kids. We are in our "starter" house, so next pool will be THE POOL. So for your decking, what did you use and why? We can choose Kool deck, stained concrete, salt wash (I think I have that right), and several other options. Thoughts..opinions??
We did colored concrete (not stained - color added to the concrete).
If you do colored concrete, my advice would be to pick the color you want, and then go one or two shades darker.
We picked the color we wanted it to look like (which wasa light tan), and it did look like that when they poured it. But once it dried, it was much lighter and doesn't look much different than regular concrete.
We have a little bit of everything. The majority of our decking is made with Kool deck. We do have a 1' border all the way around the pool that is stamped/painted concrete. It's made to look like stone. I love the look, but I will tell you that the painted concrete gets extremely hot. As far as "salt wash" goes, that's just unpainted concrete. After they pour the deck, they sprinkle the surface with pieces of rock salt which are melted away with water after the concrete has cured to leave small decorative holes. While this is appealing to the eye, it is also very hot.
I think your choice all depends on where you live. We are in Phoenix, AZ (about 1 mile from the sun these days) and the stamped/painted concrete is so hot you could honestly get 3rd degree burns on your feet. The Kool deck is hot, but definitely cooler than the concrete.
I agree with Grassy on the color. Pick the color you like and go two shades darker. We were also told to do this and I admit I was scared because the sample was so dark. I'm so glad we did. The color is even a tiny bit lighter than the one we wanted...
Good luck with your pool.
Dark = Hot it may be good to look at it but your kids feet will not appreciate it.
Brushed concrete (most sidewalks and driveways) is the cheapest option and may be perfect if this is a 'budget' pool at a 'budget' home. It is light colored and stays cooler on your feet then many more expensive options.
Stone aggregate on top is just a little more cost and also looks nice but can be rough on the feet.
concrete stains, KookDeck, and etc. can add alot of cost. In an elaborate pool it is worth the cost.


text:
Taxonomic changes »
Taxon schemes »
Make taxonomic Flickr tags for this taxon »
Flickr invite link »
Wikipedia taxobox »
Tree Browser »
Search descendant taxa »
Embed a widget for this taxon on your website »
The Garman New Guinea tree frog (Litoria jeudii) is a species of frog in the Hylidae family. It is endemic to Papua New Guinea.
Supported by


text:
on Tuesday, 31 March 2015.
We have had a couple of lovely opportunties this month to take our family photos. Firstly we went to The Grove for the night to celebrate my birthday and then secondly the weekend just gone we went to Bristol. Both would have been perfect occasions, except when we were at The Grove I forgot my tripod and when we went to Bristol it literally rained non stop all weekend. Therefore some how it got to yesterday and I realised that we hadn't taken a photo.
Therefore this month really is a rush job. We snapped these photos in the girls new bedroom just before they were going to go to sleep. We are all in our PJ's, having just got home from Bristol and put them on so we could be snuggly and cosy. To be fair I do like these photos, I have no makeup on and greasy hair, but we all look happy and the girls loved cuddling up and taking these. And actually a rush job is perfect for this month, as really it's been the theme of March for us. The month has whizzed by as usual and we have just been so incredibly busy.
We have spent the majority of the month redecorating the girls bedroom and office space, so have been living amongst havoc and mess, while the rest of the month has been spent plotting and planning. On Friday Mr E had his last day at work so from today onwards we are both going to be working together from home. It's exciting, nerve wracking and slightly daunting, but we are looking forward to this new challenge. Work is just ridiculously busy- I have taken on a couple of new roles, of which I am thrilled and pleased, but it's going to take a bit of time to get on top of things.
As such as I write this I am typing furiously ten to the dozen to get it written. We have fish and chips cooking in the oven, not particularly healthy but needs must when you are in a hurry. Then after dinner it will be non stop work until bedtime, before it all continues again tomorrow. Anyone who works from home, or indeed writes a blog will sympathise with me- life is hectic and fast paced, but we do it because we love it, and of course because it enables me to be at home with my babies most of the time.
So there we have it. April is upon us. The first half of the month hopefully will be about settling into the new routine, while the latter end of the month brings a couple of trips away. Whatever happens, I am sure it will be hectic, fun, sometimes stressful and full of memories and adventures as usual.
This month I am sending you over to have a look at my lovely friend Lucy's blog - she has also written about life being hectic recently- there must be something in the blogging water, or more the fact that it's the arrival of Spring! :)
Continue Reading
View Comments (18)
on Sunday, 29 March 2015.
Saying someone is the best person in the world is a pretty bold statement. But I am pretty sure that my Grandparents are up there with the best. I've written about both sets of my Grandparents a few times on my blog, but my Mum's parents really are truly special.
We are very lucky that they only live about half an hour away from us, so we try and pop up there every other week for some dinner or for Sunday lunch. They were farmers before they retired and they live on a big old farm which is so much fun in the Summer time- I have such fond memories of racing around the farm on quad bikes with my Uncle, or climbing to the top of the piles of wheat that had been harvested. I used to love going there to play and that's why it is so special for me to see my girls so excited to do the same, they love going to Great Grandma and Grandpas house, especially as they know that they get lots of different ice cream for pudding!
They are so proud of me for whatever I do, just as Grandparent's should be. They love to sit and listen to our tales of what we have been up to, especially my Grandpa who constantly asks if we have 'any exciting news to tell him'. They love to hear about my blog, with my Grandpa even buying an iPad especially for when he went on holiday so he could show people it when he was reading it by the pool! The thought of him showing some fellow holiday maker my blog and talking about his Granddaughter makes me cringe a little (or a lot), but his heart is in the right place and he finds the internet incredibly baffling and exciting. (If you are reading this hi Grandpa- we love you!)
I definitely get my travel bug from them, they travel the world on a regular basis, with them constantly jetting off to India, or Malaysia, or Australia for a few weeks at a time throughout my whole childhood. In fact I remember the best story of my Grandma making an Indian national newspaper for nearly falling off an elephant- there were photos of her looking panicked all over the paper and she has a couple of copies as a keep sake! They don't show any sign of slowing down yet- even in their 80's they just recently went to Thailand for almost a month and next week they are off to Italy.
They make me a 'red cross parcel' each time we see them which they have done since I left home for university- it's always been full of things like toilet roll, washing up liquid, biscuits and ketchup, but since Mads was born nappies and wipes are always in it too- in fact I can honestly say that my Grandma has funded 80% of our nappies since the girls were born- that's quite crazy really, and of course has saved us a fortune. They have been there to buy their first shoes, just as they did with me, and every couple of months my Grandma takes us all out shopping and treats us.
They really are the most wonderful people and I feel lucky every day that my children get the chance to know them- I will treasure these memories that we are making forever. They really are the most ordinary of moments, I have seen them every few weeks since I was a baby, bar when I was at university or when they or I were travelling, but even the most ordinary of moments are worth treasuring, especially as the years pass by so quickly.
Continue Reading
View Comments (27)
on Tuesday, 24 March 2015.
For the last couple of weeks we have been embarking on a couple of interior projects, which quite frankly are my favourite kind of project. This is due to the fact that we really needed an office space, as from next Monday my husband will be joining me in working from home. Being in a three bedroom house, that meant that we decided to put our girls in a joint bedroom. We decided on the largest of their two bedrooms, that used to be our guest room and then for the last few years has been both Mads and LL's nursery. It hadnt been decorated in a few years, when LL was born we just gave it some finishing touches, so it was well in need of a spot of painting.
I have had my reservations and nerves about them sharing, but we so far are two nights in and both have been brilliant- the bunk bed has been a raging success and so far LL has been fantastic in her 'big girl bed', we have had some giggling in the evening and morning, but everyone has stayed where they should be!
But anyway back to their room. I deliberated for a while on what theme to do for them- I love pastels and when looking for inspiration on pinterest, it seemed that monochrome or pastel seemed to be everywhere when it came to little people rooms, but Mads just isn't into pink or 'girly' colours. Therefore I decided on a primary colour/rainbow room with a few retro touches. I am a massively colourful person, our whole house is awash in colour, as are our clothes, so I decided it would be perfect for our little ladies.
We ended up spending a lot more than we planned too on their room, (sorry Mr E) because as usual I kept finding other things that looked nice, and these little trinkets and things just add up. I am thrilled with their new space and best of all they are too- with Mads calling it 'the best room ever'. High praise indeed.
I will try and link to as many products as possible in case anyone is after any inspiration, but here is their new happy, colourful bedroom in many, many photos...
As soon as I saw these Farg & Form cloud duvets on instagram many months ago, I knew that some day I would have to have them- and in fact I planned most of their room around the duvets! We got ours from Little Baby Company and although they are quite pricey, I absolutely love them and the bright colours. They are a Swedish brand so one thing I would say is that we struggled to find a duvet and pillow to fit the dimensions- in the end we found one almost the size in Ikea but it isn't perfect, it's fine when they are all tucked in though. The fab letter cushion is from Next and was a bargain, as was this funky geometric cushion from Tesco. (I can't find the link for that one!)
For LL's bed we went for the Farg & Form duvet in red and this gorgeous Hello Sunshine cushion from Tesco.
I found these little house shelves in Next and thought they would be perfect for trinkets above Mads bed.
How cute is this little troll? So retro. ;) It was mine when I was little and the funny little guy next to him is a nightlight from Ikea- it glows all different colours and I put him there in case Mads wakes in the middle of the night.
We have had these Ingela P Arrhenius owl nesting dolls a few years, they were in Mads old room.
The little knitted owl was also in Mads old room, made by our dear family friend's Mum, and the little Cookie Monster was a memento from our recent holiday to the Caribbean.
The rainbow and cloud garland is just so gorgeous, and was handmade by a lovely lady called Coral who I found on instagram who runs the etsy shop Velveteen Babies- I love instagram for finding creative and unique products from independent businesses.
Our faithful friend Mr Dino watches from his spot on top of Mads wardrobe.
We are thrilled with the girls bunk bed from Wayfair- I must have spent hours researching and looking into them, but we couldn't have got a more perfect choice. At first we decided on single beds, then a bunk bed but it was huge and took up most of the room. In the end we decided on the Rustic Retreat America Short Bunk bed, which is slightly bigger than a toddler bed but smaller than a single. It is brilliant and means that they have a fair few years in it, (especially as they both curl up so much) but it also gives them lots of space in the room as well. I was really nervous about it, but Mads loves it and can get up and down safely using the ladder. There is also a large guard rail on the top which means I have absolutely no worries that she will fall out- in fact it has made going to bed really exciting and fun for her, she can't wait to go to sleep. Bonus!
I love her little Etch a Sketch, she has been getting up earlier in the mornings and because we don't want her to shout and wake up LL, the Etch a Sketch is there so she plays with it for a bit before shouting us, plus it keeps in with the retro feel of the room. So far so good and it's been a massive hit- it's lovely seeing her play with toys I enjoyed as a child.
Their whole room was based around this image- it's one of my favourites and so I had it blown up large as a center piece for their picture wall.
It's hard to see their picture wall in these photos because the light from the window hits the glass frames. But I had great fun choosing prints for it.
The prints are a combination of photos, prints I have designed myself and got printed, and prints I have bought, but they all have lots of colour in common. Our frames are the trusty ones we use for all our photo walls- the Ikea Ribba frames, which are as cheap as chips and do the job nicely, although if you look really closely sometimes they aren't all the best quality.
I am so pleased with how their wall turned out bar the dusting. ;)
In keeping with the colourful, retro theme, we bought some of their toys from downstairs upstairs to live. One thing that I am thrilled about is that there is so much more space for them to play now the room is arranged the way it is.
I love these colourful little hooks, again this is from Little Baby Company and was really good value.
The lampshade was in Mads old room from before, but again it is Farg & Form. The curtains obviously are also the same brand (cloud obsession me thinks) but we just bought material and got them specially made with black out lining. All the furniture, bar their bed, is from Ikea and is their Stuva range- it's fantastic, good value and quality, and comes in loads of different combos. We were really worried we weren't going to be able to fit two wardrobes in but we managed to get two long skinny ones which do the job perfectly.
The bookshelf was again from Ikea and was I think about £12 which is just crazy. I put a load of their little trinkets on the top and the gorgeous Shakespeare quote print 'Though she be but Little she is Fierce' is from a very talented old friend of mine Ben who owns Old English Prints- I absolutely love it as it is one of my favourite sayings.
Their Toy Story characters show no signs of being forgotten about so we have them as pride of place in these cute little storage boxes I found at Next- they have one side which is chalkboard which is a nice touch. Unfortunately somewhere in the decorating period, Woody found himself lost, we have a horrible feeling we threw him in the skip with some other rubbish by mistake. RIP Woody.
'Grandma in the computer' (Mr E's Mum!) made this owl for Mads old room.
I found this little cloud plushie randomly by searching on google from a company called Sew Sew, although small, he makes a perfect little windowsill companion.
Ingela P Arrhenius again- this time from Little Baby Company. They live perfectly in this little house shelf from H and M Home.
My favourite part of their room is their bookcase shelves, just because it is full of colour. I had seen this Ribba Shelves (from Ikea) hack on loads of sites, so finally got round to doing our own. The girls love it and it really brightens up the room. I think the shelves were around £8 each so they are such a cheap way of making a room instantly more colourful.
I absolutely love these 'Sisters' letters- they are individual wooden letters but rather than spell their names I thought it would be nicer to spell out this. They are colourful and look lovely sat on their chest of drawers. The apple is from Dunelm, it's meant to be a door stop but looks great next to them.
I got this little coat stand thing from Ikea, I just thought it went perfectly with their room and although Mr E rolled his eyes when I put it in the trolley, I just couldn't walk past a colourful coat stand and not buy it. ;)
And there you have it. A colourful, happy room for my girls. I hope that sharing a room will bring them even closer together and that it is the start of a real adventure for them both. I am so pleased with the way the room has turned out and it makes me happy every time I walk in there- it's just so bright and cheerful. At the moment we have their suitcases under the bed but when I get a minute I am going to sort it out and put some toys under there, so they can really enjoy and play in there more.
If you want to see the before photos of the room click here.
You can check out my other interior posts here.
Continue Reading
View Comments (102)
on Sunday, 22 March 2015.
I have written a few times before about how when my children are poorly, I actually find those times some of the most emotional and rawest when it comes to this motherhood journey. Of course I don't like them being poorly, no one wants their child to be under the weather, but those times when they need their Mummy the most, are the times that I know I will treasure when they are all grown up.
There's something about them- I know I will look back and remember that slightly sick, sweet smell of Calpol, the feeling of how hot their little foreheads were when you touched them, and how when I wrapped my arms around them and snuggled into them tight, it felt like I was holding on to a hot water bottle. On Monday morning LL had spent the majority of the night before in our bed. I lay next to her for ages while the sun came up and her and Mr E were still in a restless sleep, and I just stared at her. I made sure I took in every inch of her little button nose, all crusty and sore from her cold, and I marvelled at how long her eyelashes were. I snuggled in close to her and took advantage of the fact she was asleep, and I put my head near hers and smelt her hair, it always smells of honey.
It's rare we stay in all day. I am one of those people who likes to be busy, I like to get us out and about even if it's just to pop into town or to the garden centre for a cake. We rarely have days in the house anymore, especially now they are older and we all get a little bit of cabin fever if we don't go out. PJ days are rare nowadays too, and there's silly things, but since I started blogging I don't remember the last time I had morning TV on that wasn't kids television. If I am at home there is normally the hum drum of children's programmes in the background or it's off because we are playing a game of some sorts.
LL has been under the weather pretty much all week- I am lucky that neither of my children are particularly sickly, (touch wood) in fact I can count on one hand the amount of times they have actually been sick since they were past that 'baby sick' stage. A lot of children permanently have colds or coughs, but again Mads and LL generally aren't really prone to them. But this week LL has been really out of sorts with a cold, cough and really high fever. Sunday night was dreadful, she didn't want to sleep in her cot, but she is also one of these little people who just can't settle in our bed, unlike her big sister, so we had a night where the three of us tossed and turned all night long.
Tuesday was supposed to be a nursery day but she really wasn't up for going. As it happens I got up and went for a run in the morning with a good friend of mine and as her son goes to the same nursery as Mads and LL, she said she would take her so I didn't have to take LL out the house. This was a rare treat so LL and I stayed in our comfy clothes and snuggled on the sofa all morning. Our nursery are pretty good and they said she could switch her hours and go in on Friday instead when she was better, so I didn't have to worry too much about working around her. Instead I did a few bits and bobs I needed to do and then snuggled on the sofa with her for hours.
I never normally do this. If we are at home, I am normally tidying or we are playing games, or I am busy doing other things if they are having a bit of quiet TV time, so it's rare we sit for a long block of time anymore and just cuddle together. It was lovely and she even had a little snooze on the sofa which never happens anymore. It was just a really lovely morning with her. And this is what I mean. These are the moments I will remember. I remember them with Mads. These are the moments I don't want to forget. The way we snuggled together and she buried her little face into my arm. The way she looked up at me every so often and I could see in her little eyes that she was enjoying this one on one time just as much as I was.
These ordinary moments. These non descript times. These are the ones that will hit me one day and give me a pang of nostalgia, the ones that will come flooding back in years to come and make me feel so bittersweet that my girls are older and don't need me like that anymore.
These are the ones that truly make me feel like a Mummy.
A Mummy who should from time to time stop and pause and relish these moments a little more than she currently does.
Some iPhone photos of our week of bugs...
She fell asleep clutching her Peppa toys that go everwhere with her.
Continue Reading
View Comments (85)


text:
|Boxing Champions | Boxing Schedule | Boxing Video | Boxing History | Pound For Pound | Lounge | The Wire | Audio | Arcade
Big Bad Booty Daddy
Join Date: Sep 2003
Location: New York
Posts: 20,632
Rep Power: 200000
Points: 2,502,099,482,294.31
Bank: 0.00
Total Points: 2,502,099,482,294.31
Comments Thread For: Corley: Mayweather is No Berto, Ortiz Will Find Out
You could say that quick, fast and in a hurry -- as soon as you can say Chop Chop -- that Vicious Victor Ortiz will realize come Sept. 17 that hes stepped into the highest stratosphere of ring talent against unbeaten Floyd Mayweather Jr.
[Click Here To Read More]
Matthysse is my god
Join Date: Jan 2010
Posts: 7,155
Rep Power: 22
Points: 17,473,233.92
Bank: 0.00
Total Points: 17,473,233.92
i think ortiz knows that hes just promoting the fight hes going to lose but get a big payday
The Money Team
Join Date: Feb 2010
Age: 29
Posts: 8,128
Rep Power: 29
Points: 574,817.54
Bank: 1,065,233,207,456,670.12
Total Points: 1,065,233,208,031,487.50
I'm so amped for this fight!!!
Join Date: May 2011
Posts: 298
Rep Power: 0
Points: 5,990.43
Bank: 0.00
Total Points: 5,990.43
Corely, are you on drugs?...
,,Jr whooped your azz back in 2004! Its 20 fn 11!!!! Get real!!!
The Don of NSB
Join Date: Feb 2010
Location: Boss Status
Posts: 11,520
Rep Power: 48
Points: 56,000,000,000,011,256.00
Bank: 2,352,094,680,208,732,160.00
Total Points: 2,408,094,680,208,743,424.00
At least Berto has power. Ortiz will walk thru all of Mayweathers punches like if they were thrown by Malinaggi.
Win Lose or Draw one thing is for certain, Ortiz will leave the fight looking just like he did when he got in.
Join Date: Jun 2005
Posts: 24,185
Rep Power: 87
Points: 7,343,444.18
Bank: 0.00
Total Points: 7,343,444.18
Berto is really a limited boxer so yeah, Ortiz might have no idea what he's getting into. He opens himself up a lot. Finishes with his left hook a lot. Floyd will exploit all of that at some point. The only question is what happens if Ortiz takes those counters and finds a way to land some of his own? Because he's a pretty good combination puncher.
At least he's longer, stronger, a southpaw, explosive. It's not something Floyd has had to deal with.
Big Floyd Fan
Join Date: Jan 2010
Location: panama
Posts: 7,396
Rep Power: 21
Points: 501,070,168,007.03
Bank: 0.00
Total Points: 501,070,168,007.03
The 2004 version of FRAUD, might not be
the same as the new, LEG heavy one!!!
All the Gym work, can't overcome the
inherited WEAK WHISKERS, and Brittle
Paws!!! any one with heavy Hands is a
RISK, For BOY, why do U think he PUNKED OUT,
against Pac???
Join Date: Jan 2010
Posts: 139
Rep Power: 0
Points: 13,100,026,845.00
Bank: 0.00
Total Points: 13,100,026,845.00
Undisputed Champion
Join Date: Sep 2009
Location: neutral corner
Posts: 2,291
Rep Power: 10
Points: 10,100,037,071.96
Bank: 12,163,472.82
Total Points: 10,112,200,544.78
I hope Ortiz is getting more money than reported, I heard rumors of $40 Million for Floyd. Floyd might have beaten a smaller, older Marquez, but I think Ortiz has something for Floyd. Lots of people ignore father time, but he never forgets you. Floyd resorted to trickeration for a cheap win and that's a sure tell. He doesn't believe he can win without an edge.
Join Date: Jan 2011
Posts: 39,104
Rep Power: 235
Points: 359,000,450,272,448.50
Bank: 3,077,029,214,736,978,280,448.00
Total Points: 3,077,029,573,737,429,073,920.00
people who think floyd has no power are hillarious
|Thread Tools
Privacy Policy - Submit
News - Feedback
- Site Map - Advertise
with Us
Copyright © 2003-2014 BoxingScene LLC All rights reserved.
Copyright © 2003-2014 BoxingScene LLC All rights reserved.


text:
"Don't trust the mainstream media!" Trust Natural News!
He is saying "do your own research," but he is also saying that everyone is lying to you. I interpreted this as 'do your own research, but make sure they agree with me.'
I did not form my opinion of Mike Adams from this article. Unfortunately I have read dozens of his articles, and I have noticed a distinct pattern of disinformation and deception. On the surface this article was motivational and informative. But it is a sales pitch. He was going off the deep end with some sensationalist rants and I think he wrote this to draw his audience back in. This is the same tactic Alex Jones uses.
I could care less that he is making a profit, my beef stems from when he gets going with pseudoscience alarmism and advocates for government intervention. It irks me when his hivemind repeats his sensationalism without ever thinking twice about it (even though he encourages it haha).
I'm glad you raised your kids using the natural method. Many people don't raise their kids like that, and they turn out fine, too. My siblings and I were all vaccinated and ate mainstream food and partook in mainstream medicine and we all turned out to be healthy, free-thinking adults.
- Login to post comments