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I defeated all the bosses and all the mirror pieces and even defeated darkmind. I also got everything in the collection room, and on the map everything is blinking so I didn't leave any chests unopen, but I only have 98% of the game done. I need 2 more percent and I'm not sure what I need to do. Please help /:
Games Guru: You might want to pick up a strategy guide and then omit what you've done and what you haven't done in the game. This is one thing that really annoys me about games. When you're that close to finishing, you should get hints as to what to do to complete a game!
Do you know where some hard-to-find treasure boxes are?
Games Guru: This game has many, many treasure chests. Most are right in front of you. Some are harder to find. Here's a clue for one of the early ones: After you get your first mirror shard in Moonlight Mansion, go through the brown door and you'll find the chest with the Rainbow Map.
oh some helpful hints, SPOILER ALERT: the game auto saves, beating the game unlocks meta knights sword, to get 100% check ur map and go to the rooms that arent GLOWING. the rooms will be gold if visited but they dont glow until u have everything in that room. with the maps help, its easy to get 100% in about a week.
what do u get from beating boss endurance????? i always die on either dark mind (red backround) or dark mind (star chase scene). smash kirby is the best on boss endurance, and stone can easily kill boss 6 (the shark dude).
in kirby nitemare in dream land how do you get to the switch in world 6 area 3
i have the game you need all chests to get boss endurance
Dear cheater: It's called "Kirby Nightmare in Dreamland." Not "Kirby in Nightmare Land." From Matt.
the lava place you need to be rock kirby and keep pressing B.
how do you get the emerald paint.please somebody help me.
those things (master hand crazy hand) are from this game
how do u save???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????? plese! my game might be broken
is it true that master hand and crazy hand (from supersmashbros.brawl) is in this game?
how do you get boss endurance! I beat game but I did not get it
it is puzzling at first but it gets easy. Get the stone power then go onto the platform next to the block then just keep using it until the block falls away. Anything that shakes the screen will work.
When you are battling Dark Mind (the eye) on the stars, how do you find an quicker way(If there is one) to defeat him? Thanks.
i need help to get on the other side of the lava place. and how do i get the other kirbies to move the big block.
where is the ninth spray can?!?! the one next to the light blue music note
i think it is either grape or gold
Hey guys need some advice. One time I accidentally stumbled into the lair of the boss Moley. I can't find his lair. Someone Help me!!!!!!!!
Tips for beating Dark Mind: Do the up move with the master sword when Dark Mind is right below you(if he ever gets below you.)
Dark Mind is freakin' easy, every boss (even the mini-bosses) is easy! There is somethin' cool though. If you beat the game, keep fighting Dark Mind and beat the game 20 times to get the gold spray can.
games pretty good got 85% to 95%
i love the spray paints!!!!!
Yeah The Last Part is Easy! I've Had 100% Alot of times But My Game Keeps Starting Over!
I love the part when you get the flame sword thing, the last part with the eye was easy, beat it in 5 minutes, maybe les
you all dont know what you are talking about, its kirby night mare in dream land not
"night mare land" and its Kirby and the amazing Mirror not the "Magic Mirror"
but still ???????? got it right. I have night mare in dream land and its ok… but if
you beat the game on normal and extra you un lock metta knight mare
i like it but i cant find these last things like spray paint because i only have 93%
PS this game is the best
It's actually easiest if you have no power at all. Shooting starts at it works the best.
Once, I borrowed it from a friend. That Dark Mind (eye) is tough…
i thought this game was called "Kirby and the Amazing Mirror", not "Kirby and the Magic Mirror".
I have the game and it gets very very very boring after you beat it


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Entrepreneurship in Devon and Cornwall: policy perspectives.
Smallbone, David and North, David J. (2004) Entrepreneurship in Devon and Cornwall: policy perspectives. In: The future of Europe's rural peripheries. Labrianidis, Lois, ed. Ashgate economic geography series . Ashgate, Aldershot, pp. 179-197. ISBN 075464054X
Full text is not in this repository.
Item Type: | Book Section |
Research Areas: | A. Middlesex University Schools and Centres > Business School |
ID Code: | 3664 |
Useful Links: | |
Deposited On: | 05 Feb 2010 11:38 |
Last Modified: | 04 Mar 2015 14:37 |
Repository staff only: item control page
Full text downloads (NB count will be zero if no full text documents are attached to the record)
Downloads per month over the past year
CORE (COnnecting REpositories)

subset: commoncrawl


text:
Giannyl.com - Giannyl Website Traffic Estimation
We have pulled stats for you about giannyl.com to help your research.
giannyl.com also reaches an unknown number of unique users each month and has 87 backlinks according to Alexa. The estimated monthly ad revenue is $ 0.00.
We estimate the website value of giannyl.com is currently at $ 0.00. Traffic and Revenue of giannyl.com is estimated to be stable within the last 3 months. The domain giannyl.com is a .com domain with the name giannyl preceding it.
The Server of giannyl.com is powered by the gwiseguy/2.0 webserver software and the server is physically located in Canada (Ontario) and uses the IP address 188.8.131.52. At the DMOZ open directory project we found no listing for giannyl.com at this time.
Updated: 02/24/2015 10:29, 6 days ago
Worldwide Rank | Monthly Users* | Monthly Pageviews* |
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$ 0.00 | $ 0.00 | $ 0.00 |
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The webserver of giannyl.com is powered by gwiseguy/2.0 webserver software. The server is located in Toronto in Canada. The IP address of giannyl.com is 220.127.116.11.More detailed:
IP Address | Subnet | AS Number | ISP | Location |
188.8.131.52 | 64.99.80 |
AS15348 Tucows.com Co. |
Tucows.com Co. | Toronto, Ontario, Canada |
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The location of the hotel is very good. It's on the Küçükçakıl Beach of Kaş, with a great view. Some rooms are renovated and they have better furnitures and beds. But beware that the standard rooms are very small and old fashioned! And the breakfast is not very good. It doesn't have an elevator (like most of the Kaş hotels)... More
- Reservation Options:
- TripAdvisor is proud to partner with Travelocity, Booking.com and Odigeo so you can book your Medusa Hotel reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Medusa Hotel Kas


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Celebrities Wearing Lace-Up Heels 2013
7 Days, 7 Ways: Lace-Up Heels to Show Off Your Pedi in Style
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7 Days, 7 Ways: Lace-Up Heels to Show Off Your Pedi in Style
Lace-up heels are all the rage this Summer, but before you shop your favorite pair, allow seven very stylish celebs to show you how they're done. Seeking some flirty flair? It's all about Emmy Rossum's ensemble. Want something a bit more streamlined? Look to Emma Roberts. And for a bohemian style, refer to Katy Perry. But they're not the only famous faces who have rocked lace-up heels recently. Click through to get inspired to work the trend every day of the week.
Read More 7 Days 7 WaysBionda CastanaKaty PerryEmma RobertsBrian AtwoodRihannaEmmy RossumCelebrity StyleShoesHalle BerryShopping
Link Love
- You're going to love these brand-new Kanye outfits — HuffPost Style
- Lupita Nyong'o's 15 greatest style moments will blow you away — Lucky
- Emily Current and Meritt Elliott created a denim destination — Who What Wear
- Wait — SkyMall may not be gone forever — The Cut
- The surprising new alternative to leather — InStyle
- Is Björk going to top our list of style icons this year? — Racked
- You need this Louis Vuitton look in your closet stat — SheFinds
- Will people still choose Gucci with Alessandro Michele's takeover? — Style.com
- How to pack light for the chicest city in the world — Man Repeller
Latest Fashion


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In a world where games often find themselves running on platforms they weren't really meant for -- Doom on your iPod, Viva Piñata on your Xbox 360 -- it doesn't come as a terrible surprise when Crytek CEO Cevat Yerli declares, "Theoretically, anything could run anywhere." Speaking to the UK's PC Gamer Magazine (via CVG), Yerli asserted that his company's graphically splendorous PC shooter could eventually find its way to high-end consoles. "Crysis could be on the 360 or PS3," he said. "It requires optimisation, that's what we've always communicated."
However, technical feasibility doesn't guarantee a thing and confirmation of console ports remains elusive as ever. "What you would not do is make Crysis on PS3, 360 and PC for a single shipping date, because we would lose the quality focus," Yerli noted. "So I say, 'First PC version, then we'll see what happens.'" If Epic's Mark Rein is to be believed, what happens is that Crytek considers downscaled console versions of Crysis in order to capitalize on a market outside of cutting-edge PCs.
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Off the Grid: The Witcher Adventure Game and Star Wars Imperial Assault
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Others::Others > Ace Ping 1.2
Ace Ping 1.2Ace Ping provides constant control over the status of your network. Company: FOMINE SOFTWAREPlatform: Win95,Win98,WinME,WinNT 3.x,WinNT 4.x,WinXP,Windows2000 Size: 144 KB Price: USD $9.95 Release Date: 2002-05-20 Screenshot URL: http://www.fomine.com/products/images/ping1.gif Category: Others::Others Ace Ping provides constant control over the status of your network and remote computer. It automatically carries out a ping over specified intervals of time. The color of the icon in the system tray changes according to the quality of the connection with the remote computer. The latest version features full support for Windows XP. Related keywords: constant control status network ping Ace Ping Related Titles: We buy any car 2.0 - Keep an eye on your childrens internet activity with our FREE keylogger!Lexilogos arabic keyboard 1.0 - Lexilogos arabic the virtual arabic keyboard with transliteration Clavier arabe co 1.0 - Clavier arabe co the virtual arabic keyboard to write arabic Google Sniper 3.0 - Before Google Sniper 3 there was just Google Sniper. Genius Connect - Notes 188.8.131.52 - Sync Outlook or Exchange Notes to any SQL Database Ricks Yellow Page Scraper 1.0 - Rick?s YellowPages.com Scraper gets information based on your search criteria an Titan Browser 1.0 - Titan Browser is a browser that combines a minimal design... SatelliteDirect TV for PC 2014.419 - Watch over 3,500 TV channels on your laptop or desktop PC anytime. Karusela 1.0 - Karusela Site Viewer is a fast windows app that will keep you up to date with us Recover Doc Document 5.3 - Recovery for Doc files to repair damage data of word file via Word File Recovery FBmatic Free Facebook Marketing Software 1.0.1 - Finally... A Legitimate Work Smart - Not Hard Software to Automate facebook PC Optimizer 1.0 - PC Optimizer is a free tool that will help you clean and optimize your PC. |
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Earthly Elements by Solgar, Volumizing Conditioner, Moroccan Vanilla, 12 fl oz (355 ml) (Discontinued Item)
By Earthly Elements by Solgar
Write a Review-
Shipping Weight:?1.06 lbs (0.48 kg)
Shipping Weight
The Shipping Weight includes the product, protective packaging material and the actual shipping box. In addition, the Shipping Weight may be adjusted for the Dimensional Weight (e.g. length, width & height) of a package. It is important to note that certain types of products (e.g. glass containers, liquids, fragile, refrigerated or ice packed) will often require protective packaging material. As such, these products will reflect a higher Shipping Weight compared to the unprotected product.
- Product Code: EES-52418
- UPC Code: 033984524187
- Package Quantity: 12 fl oz (355 ml)
- Dimensions: 2.2 x 2.2 x 7.9 in, 0.9 lbs (0.41 kg)
Product Overview
- Hair Care System
- Leaves Your Hair Voluminous Hydrated and Energized
- This Bottle is Recyclable and Decorated with Earth-Friendly Processes
- 100% Vegan
Brimming with protective nutrients for your hair; Earthly Elements conditioners are ideal for even the most sensitive scalps and give your hair a natural, silky finish for maximum sheen.
Our Moroccan Vanilla Volumizing Conditioner softens and protects, while giving your hair a vibrant bounce and a natural healthy gloss.
Simply Created with: | |
Moroccan Vanilla Volumizing Conditioner is created with volumizing nutrients to penetrate your hair, leaving it soft and manageable. |
Created with your serenity in mind, Earthly Elements brings you the harmony that you're meant to experience in your life's journey.
Suggested Use
After shampooing with Earthy Elements Moroccan Vanilla Volumizing Shampoo, massage into hair, concentrating on the ends. Rinse thoroughly.
Other Ingredients
Purified water, aloe barbadensis leaf juice, helianthus annuus (sunflower) seed oil, stearalkonium chloride, hydrolyzed barley protein, simmondsia chinensis (jojoba) seed oil, cetyl alcohol, glyceryl stearate, alpha-glucan oligosaccharide and polymnia sonchifolia root juice and maltodextrin and lactobacillus, panthenol, morinda citrifolia (noni) juice, vanilla planifolia (vanilla) extract, soy protein, linum usitatissimum (flax) seed oil, tocopherols, ascorbic acid, brassica oleracea italica (broccoli) seed oil, vaccinium macrocarpon (cranberry) seed oil, citric acid, sodium benzoate, potassium sorbate, ethylhexylglycerin, natural aroma blend
Simply made without the use of:
- Parabens, glycols, SLS, phthalates, silicones, EDTA, artificial fragrances or petroleum based ingredients
No animal testing
Due to our unique natural ingredients, the color, scent and consistency of each product may vary.
For external use only. Do not ingest.
Keep out of reach of children.


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31 year old man | Coral Gables, FL, USA | Seeking women 21-35 within 10 miles of Miami, FL
Active within 5 days
Everything has beauty, but not everyone sees it.
I enjoy life and the moments I get to spend with my family and friends, I think that they would best describe me as caring, friendly, kind and understanding. If i'm not at the gym working out, you would probably find me listening to live music or going to a concert. I work out often because not only is it my hobby but its a way of life for me. Also, I enjoy watching movies, bbq's with friends or driving around the city to find new restaurants or things to do. Through my work I've traveled to Curacao, Dominican Republic, Aruba, Turks and Caicos, Colombia, Panama, Uruguay, Argentina, and Peru. I would like to find a woman that is intelligent and confident. Someone who shares my similar interests and hobbies.
Coffee and conversation , Dining out , Movies/Videos
Basketball, Billiards / Pool, Dancing, Football, Martial arts, VolleyBall, Weights / Machines, Yoga
I exercise 5 or more times per week.
I like Birds, Cats, Dogs, Exotic Pets, Fish, Horses
Village at Merrick Park, Miami Beach, and Miracle Mile.
Florida International University, Miami, FL
Comedy, Stocks, Fine watches, Sports Cars, Real State.
Movies, Restaurants ,Working out , Shopping , Music( too many : Phil Collins, Frank Sinatra...)
The Intelligent Investor.
Him | What he is looking for | |
Appearance | ||
Height: | 5'10" (177cms) | 4'0" (121cms) to 7'0" (213cms) |
Body type: | Athletic and toned | No preference |
Eyes: | Black | No preference |
Hair: | Black | No preference |
Lifestyle | ||
Smoke: | No Way | No Way |
Drink: | Social Drinker | Never, Social Drinker |
Occupation: | Technical / Science / Computers / Engineering | No preference |
Systems Engineer |
Income: | I'll tell you later | No preference |
Relationship: | Never Married | No preference |
Have kids: | No | No |
Wants kids: | Someday | No preference |
Background | ||
Ethnicity: | Latino / Hispanic | No preference |
Cuban |
Faith: | I'll tell you later | No preference |
Languages: | English, Japanese, Spanish | English, Spanish |
Education: | Bachelors degree | No preference |


text:
Leonardo DiCaprio and Toni Garrn Kissing In Spain | Pictures
Leonardo DiCaprio and His Bikini Babe Hit Up Spain
Leonardo DiCaprio watched as his model girlfriend, Toni Garrn, slipped into a bikini for a day by the pool in Ibiza today. Yesterday, the couple showed some serious PDA while on a boat. Leo and Toni, who have been linked since May, met up with a group of friends on the vessel and were spotted cuddling and making out during their outing, marking the first time we've seen Leo and his new lady getting physical in public. Since hooking up with Toni at the Cannes Film Festival earlier this year, Leo has spent the majority of the Summer overseas — he packed in plenty of tourist time at nightclubs, museums, and the French Open in Paris.
Leo's Summer of fun may soon come to an end as he gears up to promote The Wolf of Wall Street, which hits theaters in November. We'll have to wait and see if Toni pops up on the red carpet with her leading man when he begins doing press for the film with costars Matthew McConaughey and Jonah Hill. In the meantime, though, we encourage you to check out the best GIFs of Leo from the movie's trailer.
- Is Khloé Kardashian set to replace Kelly Osbourne? — People
- Bobbi Kristina Brown's family is reportedly shooting a reality show — Us Weekly
- Inside Justin Bieber's wild 21st birthday — Gossip Girl
- Ashton Kutcher may be switching career paths — OK!
- This Jenner reveals she's more spiritual than materialistic — HuffPost Celebrity
- Tom Hanks explains how he landed a role in Carly Rae Jepsen's music video — ET
- Madonna is spotted in Milan promoting her album Rebel Heart — Lainey Gossip
- Nick Jonas on his first song that he auditioned with at 6 years old — BuzzFeed


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The Afghanistan Cricket Board (ACB) is keen that the BCCI and the international community in its country add to the existing resources and provide a thrust to the development of the game.
The ACB has identified coaching, umpiring and scoring as the core aspects for immediate attention and asked the BCCI to make a significant contribution on these areas.
Shahazadah Masood, Advisor Minister & Chairman, ACB and Basheer Stanekzai, High Performance Programme Manager, ACB met Sanjay Jagdale, Secretary, BCCI and Ratnakar Shetty, General Manager, Game Development, BCCI at the Cricket Club of India (CCI) on Sunday and asked them to open up opportunities for its under-19 team.
Good meeting
"We had a good meeting with them and the response has been very positive. We want help to develop our technical staff like coaches, umpires, scorers and video analysts.
"The natives in Afghanistan are making a big contribution to the social side and hence we want the international community to support cricket," said Masood.
The ACB officials have agreed to adhere to the BCCI guidelines that eliminates middlemen or agents who facilitate tours to India at a cost for advance training and playing practice matches.
The ACB has selected a new under-19 squad and it will take part in the Asian Cricket Council (ACC) under 19 cup at Malaysia this May. According to Stanekzai the recent positive developments in his country has pointed to an increase in interest for cricket than football.
Keywords: Afghanistan Cricket Board, BCCI support


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©2003 Peg Kehret; (P)2009 Audiobookshelf
Audible has been a friend, a companion, and even a connection with my daughter as the process of physical recovery continues.
"Wrong Narrator"
This was, for the most part a nice little kid's story; though much of the middle portion of the narrative was pretty tedious. However the middle aged male narrating this tale from the perspective of a thirteen year old just didn't work. Indeed it was just so jarring, that at times it completely distracted from the story. I know that it's probably impossible to find a thirteen year old male capable of reading an audiobook but I find it hard to believe that a better reader couldn't have been located.
"Very good short story"
Enjoyed listening to this, it is only a short story lasting just over 2 hours but great for listening too in the car
"Reader too old to narrate this story!!"
I recommend the book, but not this particular audiobook. It was very disconcerting to hear a grown man read the voice of the 13 year old narrator. It's a great story, though. Perfect for readers ages 9-12.
"This was a great read!"
I wouldn't rent this particular book again, since it was for my daughter to read for her book club. She really enjoyed the experience and loved being able to relax and lay on her couch, while listening. Great time, great book.
There are no listener reviews for this title yet.


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HOME > Amish In The City
Amish In The City
Ratings: UPN's controversial 'Amish in the City' scores big in premiereLooks like U.S. reality TV viewers have figured out -- after 9 years -- where to find UPN, the smallest of the 6 U.S. broadcast networks, on their sets. Full Story |
UPN releases 'Amish in the City' contestant details, screens premiere for TV critics group
Now that UPN secretly completed its controversial reality-documentary series Amish in the City, which will air beginning July 28, some details are finally reaching the public. This week, UPN announced personal details about the 11 young people (5 Amish, 6 not) chosen for the show and also screened the first episode during the Television Critics Association press tour.UPN's 'Amish in the City' to premiere July 28
Give Les Moonves, the head of TV networks UPN and CBS, credit -- he's learned through bitter experience that with reality TV, sometimes it's best to avoid the media limelight altogether.
- Exclusive: 'The Amazing Race' couple Jeff Magee and Lyda Grawn talk (Part 2)
- 'Keeping Up with the Kardashians' reportedly gets picked up for a few more years
- Kendall Jenner and sister Kylie Jenner reportedly being considered to star in new E! spinoff
- Kanye West gets tattoos on his wrists to show love for two girls
- 'American Idol's Top 12 girls perform, standouts include Jax, Tyanna Jones and Sarina-Joi Crowe
- Exclusive: 'The Amazing Race' couple Jeff Magee and Lyda Grawn talk (Part 1)
- Exclusive: 'Survivor: Worlds Apart' eliminee So Kim talks (Part 1)
- 'The Amazing Race' ousts dating couple Jeff Magee and Lyda Grawn in debut episode
- Kylie Jenner buys $2.7 million mansion at age 17
- 'Survivor: Worlds Apart' White Collar "Masaya" Tribe votes off So Kim in premiere
- 'American Idol's Top 12 guys perform for votes and some rise above the pack
- 'Survivor: Worlds Apart' host Jeff Probst: The cast is the best yet, the three tribes live up to stereotypes
- 'The Amazing Race' host Phil Keoghan on new season: The format hasn't changed, it's not a dating show!
- 'The Bachelor' eliminees Britt Nilsson and Kaitlyn Bristowe weigh-in on which girl should win Chris Soules' heart
- Bobbi Kristina Brown taken out of a coma in the hope of change, says family source
- Kaitlyn Bristowe: 'The Bachelor' star Chris Soules wasn't courteous enough to dump me in a legit conversation
- Giuliana Rancic publicly apologizes to Zendaya Coleman for Oscar dreadlocks joke on 'Fashion Police'
- 'The Bachelor' star Chris Soules: "I'm still in love" with the woman I picked!
- Demi Lovato rushed to hospital with health scare, doing much better now
- 'America's Next Top Model: Guys & Girls 2' contestant Mirjana Puhar killed in triple homicide
- 'The Voice' coaches all fight for once-rejected artist Deanna Johnson in Blind Auditions
- Kelly Clarkson: I no longer rely on my career for my self-worth, my world has changed
- Tyga: It's all love there with Kylie Jenner and it doesn't matter what the world thinks
- 'The Bachelor' host on 'Women Tell All:' Kaitlyn Bristowe is mad, one girl still really loves Chris Soules


text:
13801 Coastal Highway, Ocean City, MD 21842, United States of America – Show map
Loved the hot tub. The staff were also really nice, and the downstairs game room & vending area was very good. The hotel generally could use some TLC, but for the price it's fine. The Bar/pub on the 8th floor was impressive, don't miss this!
United States of America
Loved the pool, hottub, bar, and location.
United States of America
This is a old hotel so take it for what it is. Good parking, indoor pool and hot tub. Food was good at their roof top restraurant, was a little chilly but it is a really cold winter. Room was clean, service was good, price was good, I enjoyed the weekend.
United States of America
I have stayed here numerous times. Although the Fenwick is a older hotel, it is well maintained. It appears the rooms have been updated with new flat screen TV's. It has always been clean and comfortable.
United States of America
We really liked breakfast, but second day you were closed due to electrical issues.
United States of America
The upstairs band and bar
United States of America
The hot tub and pool facility were very nice.
United States of America
Convenient location.
United States of America
The Food at the Roof Restaurant was awesome,
United States of America
Just going through and needed a bed and coffee. They had it, I slept well.
United States of America
Featuring an indoor pool and a restaurant, Fenwick Inn is in north Ocean City, just over half a mile from Fenwick Island. The beach is 100 yards away and Lost Treasure miniature golf is just 50 yards from the property. Free Wi-Fi access is available.
At Fenwick Inn, guests can enjoy a rooftop restaurant and lounge, a hot tub and a 24-hour front desk. Other facilities include a game room and a vending machine. The property provides free parking.
The rooms include a microwave, refrigerator, air conditioning and a TV. The private bathrooms have a bathtub or a shower.
Fenwick Inn is just under a mile from Thunder Lagoon water park. Salisbury-Ocean City-Wicomico Airport is 33 miles away.
North Ocean City is a great choice for travelers interested in Seafood, Restaurants and Food.
We speak your language! Hotel Rooms: 201 This property has been on Booking.com since Jan 28, 2014.
Low rates
No booking fees • Save money! Best price guarantee — enter dates to see these prices!
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Including hotels, apartments, villas and more.
410 verified reviews
We verify all reviews from guests who have stayed at Fenwick Inn. Find out more.
They speak your language!
Fenwick Inn's staff speaks: English
Booking is safe
When you book with us your details are protected by a secure connection.
Grounds, Sun Deck
Pool Table, Hot Tub, Indoor Pool (all year), Game Room
Food & Drink
Bar, Restaurant with Dining Menu
WiFi is available in all areas and is free of charge.
Free public parking is available on site (reservation is not needed).
Room Service, Vending Machine (drinks), Vending Machine (snacks), 24-Hour Front Desk, ATM on site, Daily Housekeeping, Meeting/Banquet Facilities, Fax/Photocopying, Honeymoon Suite
Non-smoking Rooms, Facilities for Disabled Guests, Elevator, Heating, Air Conditioning
From 4:00 PM
Until 11:00 AM
Cancellation and prepayment policies vary according to room type. Please enter the dates of your stay and check what conditions apply to your preferred room.
Children and Extra Beds
All children are welcome.
Up to two children under 18 years stay free of charge when using existing beds.
Up to two older children or adults are charged USD 10 per person per night when using existing beds.
One older child or adult is charged USD 10 per night in an extra bed.
One child under 2 years stays free of charge in a crib.
The maximum number of extra beds in a room is 1.
Any type of extra bed or crib is upon request and needs to be confirmed by management.
Additional fees are not calculated automatically in the total cost and will have to be paid for separately during your stay.
Pets are not allowed.
Cards accepted at this property
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Latest booking: 2 hours agoFrancis Scott Key Family Resort
Latest booking: 9 hours ago
Located on the bay next to the Gold Coast Mall and two blocks from Ocean City Beach, the Comfort Inn Gold Coast is the hotel for business and leisure travelers.
Score from 362 reviews
Very good
This Ocean City, Maryland hotel is just steps from the beach and boardwalk and features an outdoor pool and on-site restaurant. The boardwalk amusement rides are one mile away.
Score from 261 reviews
Very good
Featuring a splendid oceanfront outdoor pool and a fitness center, the Crystal Beach Hotel is conveniently located in Ocean City, right on the beach and boardwalk. Free Wi-Fi access is available.
Score from 328 reviews
This hotel is on the shores of the Atlantic Ocean in Ocean City, Maryland. It features an on-site restaurant and a beach. Rooms at Beach Plaza Hotel feature free Wi-Fi and a TV.
Score from 407 reviews
Thank you for letting us bring our Pomeranian. Also, room service was terrific!
Loved the hot tub. The staff were also really nice, and the downstairs game room & vending area was very good. The hotel generally could use some TLC, but for the price it's fine. The Bar/pub on the 8th floor was impressive, don't miss this!
The pool was designed poorly - there was water dripping from the ceiling all over the place (I was at the hotel at the end of Feb)
This is a old hotel so take it for what it is. Good parking, indoor pool and hot tub. Food was good at their roof top restraurant, was a little chilly but it is a really cold winter. Room was clean, service was good, price was good, I enjoyed the weekend.
Black mold in bathroom.. no smoking.. even though that was an option online.. Power went on and off and restaurants were closed. Ice formed on the inside of the windows and soaked the curtains and floors... just wow.
I have stayed here numerous times. Although the Fenwick is a older hotel, it is well maintained. It appears the rooms have been updated with new flat screen TV's. It has always been clean and comfortable.
Ice maker on our floor was broken
We really liked breakfast, but second day you were closed due to electrical issues.
That the room was so shabby and beat.
The room services of the restaurant
Dusty in the room. It looked old. The wifi wasn't good. The room wasn't updated at all
The hot tub and pool facility were very nice.
There was a LOT of noise in evenings and on one morning it awakened me before 7:30 AM. It was annoying el enough for me to visit the front desk twice. There did not seem to be anything that the front desk personnel could do to make it stop.
The pool and the hot tub were absolutely disgusting! Balls of hair floated around as we tried to swim and the pool chemicals were so high that my eyes and skin burned so I had to get out. There were no towels in the pool room as they promised there would be. The front desk staff were less than hospitable and had a bad attitude when you asked them for something. The rooms were outdated and the tv in our room had a big black mark down the middle of the screen making it hard to watch the tv. For the price we paid in the off season, we were very disappointed and will stay elsewhere when we travel again.
Convenient location.
Facilities are a little dated, vent in bathroom would be nice. Heat/air conditioner a little loud.
Your employee at the front desk name Charles.
The Blinds, the ice maker didn't work and the floor location and the TV.
Checking out
The staff was not friendly. The Wi-Fi was horrible. When I checked in In The front desk let me know the hours of the restaurant so I could get breakfast in the morning. When I showed up the next morning for breakfast the restaurant was closed for the season
Room was like the north pole when we entered. Ceiling falling apart, wallpaper coming off the wall, grout in bathroom never cleaned
The Food at the Roof Restaurant was awesome,
Asked for a Tea bag was told they ae available only from 8-11am. Some other nice gentleman finally gave me one. Shower Head was not working properly. Stain in front of Bathroom Rug. No Coffee Pot in Room. Tv reception was noy too good. Decor was old. Pool area was old especially the Hot Tub. We will not be back. Hallway was very cold Friday night, was ok Saturday.
Just going through and needed a bed and coffee. They had it, I slept well.
I didn't stay long enough to find out.
I asked to book a quiet room. I got next to the ice machine. checked out the next day
the location, the room was comfortable, and the bar was good after the Ravens game was over.
the Ravens Roost where they could only air the Ravens game. My room key did not work and they had to have maintenance change my lock, which took awhile.
Staff was super friendly. The bed was like a dream. The room was clean and large.
There was a musty smell, the wallpaper was peeling and there were a lot of cracks in the ceiling. Seemed like they should do some remodeling.
Price was reasonable
Water pipe directlly behind headboard so every time toilets were flushed on floors above our 3rd floor room it felt and sounded like a water fall right behind our headboard. Light in bathroom was very dim and eventually went out completely.
When presented witht the insect problem relocated us promply without hesitation.
Found bugs in bed and room


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Britney Spears' Torn Stockings
Britney tweeted this picture during a break from shooting her new video for "Till The World Ends." She needs new stockings.
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07/11/2012 Gophers Place 86 on Big Ten Distinguished Scholar ListList of student-athletes with a 3.7 or better GPA grows by 26 percent 05/31/2012 149 Gopher Student-Athletes Earn Academic All-Big Ten HonorsMinnesota's Total is up from 123 Following the 2011 Spring Seasons 05/13/2012 Minnesota Rowing Places Fifth at Big Ten ChampionshipsKalmoe and Haws named to All-Big Ten teams. 05/11/2012 Rowing Set to Compete at Big Ten ChampionshipsThe event will take place Sunday in Indianapolis, Ind. 04/29/2012 Minnesota's First Varsity Four Notches Win vs. WisconsinThe squads faced-off on Lake Phalen in St. Paul. 2011-12 Senior Season: Defeated Kansas, Buffalo and Dukeas 2V8 in the Oak Ridge Invitational (3/17-18) ... Defeated Indiana as 2V8 in the BigTen Double Dual (4/7) ... Raced in the Virginia Invitational as 2V8 (4/14-15) ... Rowed against Wisconsin as 2V8 in the Home Dual vs. Wisconsin (4/29) ... placed fifth in the Big Ten Championships 2V8 (5/13) ... Academic All-Big Ten honoree 2010-11 Junior Season: Earned the Big Ten Distinguished Scholar-Athlete award ... competed with both the First Varisty Four and the Second Varsity Eight during the season ... placed fifth with the 1V4 at the Big Ten Championships (5/15) ... rowed with the 1V4 at the Wisconsin Dual (5/1) ... placed first by defeating Louisville, Syracuse and Boston University with the 2V8 on day two of the Charles River Challenge (4/18)... also finished first on the opening day of the Charles River Challenge (4/17) ... competed in the Second Varsity Eight at the Big Ten Double Duals vs. Michigan and Michigan State (4/9) ... defeated Tennessee in the 2V8 at the Tennessee Dual (3/20). 2009-10 Sophomore Season: Helped the Third Varsity Eight to a win over Kansas (4/24) ... competed with the 4V8 at the Head of the Iowa (10/25) ... finished second in the Women's Collegiate 4+ event at the Head of the Mississippi (10/4) ... raced in the Women's Collegiate 8+ at the Head of the Mississippi (10/4). 2008-09 Freshman Season: Began her Gopher career with the Novice A Eight at the Head of the Mississippi (10/5) and won the event ... competed at the North Star Challenge with the Novice A Eight (10/25) ... raced with the Gopher A Novice Eight at the Southland Regatta (11/2) ... member of the 2N8 that won the Women's Collegiate Novice B Final at the San Diego Crew Classic (4/4) ... moved up to the First Novice Eight at the Double Duals (4/11) ... sat in the six seat in the 2N8 win over Kansas (4/25) ... member of the 2N8 that finished second in the Petite Final at the Big Ten Championships (5/2). Previous Rowing Experience: Attended several camps, including Princeton University camp, where she was named the most improved rower ... attended the Northeast Rowing Camp in Maine and was a member of the time trial and was apart of the fastest boat in the camp. Personal: Born January 9, 1990 ... plans to major in kinesiology ... daughter of Sherry and Bob Bourgeois ... graduated from Whitefish Bay High School in 2008 ... was a swimmer for over 10 years and earned four letters in the sport ... qualified for the state meet in her junior and senior seasons. |
More Headlines
2/22/2015Gophers Ready for Spring Schedule
2/11/2015Catching Up with Coach Davis
12/30/2014Minnesota Signs Six Rowers for 2015-16
10/25/2014High Winds Force Gophers Inside
10/24/2014Gophers Head to Madison for Scrimmage
10/12/2014Gophers Solid at Head of the Rock
10/11/2014Gophers Set for Head of the Rock
10/06/20142014-2015 Rowing Season Preview
10/05/2014Gophers Shine at Head of the Mississippi
09/30/2014Hodnett Prepares for Final Season


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sorted by: Alphabetical: A-Z Alphabetical: Z-A Newest (by date approved) Newest (by date created)
Windmill Onze Lieve Vrouwe Geboorte
in Windmills
Small poldermill near Zegveld
posted by: naj16
location: Zuid-Holland, Netherlands
date approved: 2/28/2015
last visited: never
Sint Nicolaasmolen "Nije Moll" - Denekamp (NL)
One of the two windmills in Denekamp, The Netherlands
posted by: Axel-F
location: Overijssel, Netherlands
Borgelinkmolen - Denekamp (NL)
One of the two windmills in Denekamp, The Netherlands.
Windmill Meije
Small poldermill near Meije
Windmill Windlust - Noordwolde NL
Windmill named Windlust located at 29 Industriestraat in Noordwolde, The netherlands.
posted by: dreamhummie
location: Friesland, Netherlands
date approved: 2/27/2015
last visited: 2/27/2015
Windmill Kleine Wielen
Small poldermill in nature reserve Kleine Wielen
date approved: 2/22/2015
The Oasis Water Windmill - Austin, TX
A water windmill at The Oasis at Lake Travis in Austin, Texas welcomes visitors as they walk across from the parking area to the restaurant.
posted by: Raven
location: Texas
date approved: 2/11/2015
last visited: 8/23/2014
Madeley Windmill - Madeley, Telford, Shropshire
The Madeley Windmill is located just off the Silkin Way Path, in Madeley, Telford, Shropshire.
posted by: GCMTWood
location: West Midlands, United Kingdom
date approved: 2/8/2015
[MoL] Le moulin de Bel-Air
Découverte du Moulin de Bel-Air à Guilly (Loiret / Centre / France).
posted by: # Wolverine #
location: Centre, France
date approved: 2/6/2015
last visited: 2/8/2015
Water Windmill - Guymon, OK
Display in public park
posted by: YoSam.
location: Oklahoma
date approved: 2/3/2015
Guerande Windmill
Fr : Le moulin de Crémeur, dit moulin du Diable, est un moulin situé à Guérande, en France En : The mill "Cremeur" nicknamed the Devil's mill, is a mill located in Guerande , France
posted by: DD Drix
location: Pays de la Loire, France
date approved: 1/24/2015
last visited: 1/24/2015
Vetrny mlyn Skalicka/ Windmill Skalicka
Drevený vetrný mlýn nemeckého typu, který je príležitostne prístupný verejnosti. Wooden windmill of german type errected now in Skalicka, you can visit it after preceding agreement on telephone number.
posted by: Macamica
location: Olomoucky kraj, Czech Republic
date approved: 1/21/2015
Windmill Weesp
Next to the N236 there's this new windmill
location: Noord-Holland, Netherlands
date approved: 12/28/2014
Lickety Splitz Wind Turbine - North Conway, NH
This is a small private wind turbine located along Route 16 on the grounds of Lickety Splitz ice cream shop in North Conway, New Hampshire.
posted by: silverquill
location: New Hampshire
date approved: 12/13/2014
Lois Road Windmill - Sanger, TX
An Aermotor windmill stands in the center of Lois Road as it reaches the end of the line, with Lake Ray Roberts not far away to the east.
posted by: QuarrellaDeVil
date approved: 12/11/2014
last visited: 12/10/2014
Aselager Mill - Aselage-Herzlake, Germany
In the year 1809, a corn windmill was built in Aselage for the amount of 2500 Reichstaler
posted by: g300td
location: Niedersachsen, Germany
date approved: 12/1/2014
Holländermühle Benz, Usedom, Germany
The main attraction in Benz
location: Mecklenburg-Vorpommern, Germany
Robinson Ranch Windmill - Rancho Santa Margarita, CA
A windmill along Robinson Ranch Rd.
posted by: bluesnote
location: California
date approved: 11/25/2014
Moulin Rouge Windmill - Paris, France
The windmill is located at the famous Moulin Rouge in Paris, France.
posted by: Marine Biologist
location: Île-de-France, France
date approved: 11/19/2014
Wynmotor De Knipe - De Knipe
Deze (Amerikaanse) molen is oorspronkelijk gemaakt door de dorpssmidLubbert van der Laan (1881-1952) uit Garijp. Na vele jaren in vervallen toestand is de windmotor in 2013 gerestaureerd.
posted by: haxepaxe
date approved: 11/4/2014
Windfarm near Helenenberg, Germany
This wind farm is viewable by motorists traveling on Highway 51 near Helenenberg, Germany.
posted by: Queens Blessing
location: Rheinland-Pfalz, Germany
date approved: 11/2/2014
Standerdmolen", Mierlo, Netherlands
Windmill type "Standerdmolen", Mierlo, Netherlands.
posted by: Barjon
location: Noord-Brabant, Netherlands
date approved: 10/20/2014
Windmill Vierambachtspolder
small poldermill in Vierambachtspolder
date approved: 10/18/2014
Moulin de Levreau - Bougneau (Charente-Maritime), France
[FR] Un moulin pas loin de Pons dont on connaît pas la date d'édification. [EN] A windwill near Pons. The date of its construction is unknown.
posted by: RakeInTheCache
location: Poitou-Charentes, France
Founder's Park Windmill - Anaheim, CA
This windmill is located in the back of the historical park.
date approved: 10/16/2014
last visited: 1/10/2015


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Lea Michele Album Preview
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Lea Michele is an incredibly talented young actress. She stars on the Fox hit Glee. Michele is best known for her work on Broadway. She...
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- Lea Michele Sarfati


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Fun-loving Living Room
Thomas J. Story
The bubble chairs were a splurge in this Scottsdale, Arizona living room. A see-through fireplace helps keep the room bright and serves both the living room and the patio outside.
Get This Look
Bubble Chairs: from Room Service; Fireplace: Twilight II gas fireplace from Heat & Glo
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We're not quite sure how, exactly, a romantic dramedy about a fractured family and budding love affairs is supposed to involve a frolicking farm bird. But as we can tell from these new exclusive images from the movie Crazy Kind of Love, there is, indubitably, a living wild turkey making its home amongst the emotionally ravaged human cast members. The film, which stars Virginia Madsen, Sam Trammell, and Zach Gilford as members of a family attempting to repair their relationships, might boast romance, drama, and comedy, but it's clearly got an air of mystery to it, as well: that surrounding the question of what the heck these people are doing with that turkey. Peruse the images for clues, and check out Crazy Kind of Love in select theaters May 31.
Follow Michael Arbeiter on Twitter @MichaelArbeiter
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Welcome, Sign In
Team Sky Rider Alex Dowsett Talks to Cyclingnews - Part 1
Description:Alex Dowsett is part of the new generation of British riders who have developed through the Great Britain development programme and are now successfully confirming their talent with Team Sky. Watch his in-depth interview with Cycling News. Part 1 of 3. (4:30)
Source: Cycling News
Tags: Team Sky Rider Alex Dowsett Interview - Part 1 , Alex Dowsett , alex dowsett 2011 , alex dowsett interview


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- Location: Mexico
- Spoken language(s):Spanish
Sex Questionnaire
Do you enjoy cyber-sex? SI
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Do you enjoy oral sex? MUCHO, ME ENCANTA MASTURBAR PENES CON LA BOCA
Do you enjoy anal sex? NO
What is your favorite sexual fantasy? TENER PAREJA ESTABLE
What do you look for in a sexual partner? QUE SEA PERSONA SENCILLA, SIN POSES NI NADA
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Product Description
Available while supplies last.
This product by KALCO Lighting is available in a satin nickel finish. It is available with clear bubble glass. Illuminated by three 100-watt clear incandescent bulbs.
The Cirrus bowl pendant has several strips of bubble glass overlaid one over the other to form an intricate half-moon shape, held in place by numerous thin wires and rods.
Finish: | Satin Nickel | |
Glass: | Clear Bubble | |
Light Bulb: | (3)100w A19 Med C Incand [Compare Bulbs] | |
Voltage: | 120 volt | |
Weight: | 27 Pounds | |
Installation: | Dry Locations [Explain] | |
Listing: | ||
Shade Material | Crystal Shades |
Bulb sold separately
Dimensions & Weights
Diameter: | 24 inches |
Canopy: | 6 inches |
Chain/Cord: | 8 feet |
Wire Length: | 13 feet |
Canopy Height: | 1¼ inches |
Height: | 29¾ inches |
Chain: | 8 feet |
Wire: | 13 feet |
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Category | Large Pendant Lighting - 442 |
Style | Modern - 3 |
Sales Rank | 677 |
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US 7501290 B2 Abstract A method for making suspended microarray readings from a single sample statistically significant in a reliable manner. It can be applied to any assay system that uses discrete particles where the particles are coupled with an assay. Most of these systems suspend the particles in fluid and read the assay result using flow cytometry. However, other methods such as the distribution of tiny assay devices coupled with miniature transponders, where the sampling is of the environment, can also make use of this method. This invention combines multiple separately identified assays of one sample, where the multiple assays are for a single analyte and sets of assays have differing sensitivity to said analyte. By elimination of outliers, averaging, and taking ratios of averages, this method makes possible highly reliable diagnostics. This method compensates for multiple stochastic and non-stochastic sources of errors that can occur in this type of assay system.
Claims(17) 1. A method for improving the statistical significance of readings from a single sample, the method comprising:
a. performing a first assay on a microparticle media for reading by an instrument, the first assay comprising;
i. m number of SMPCS-IDG assays targeted at a common analyte;
ii. wherein each said SMPCS-IDG assay is designed to exhibit a different response level to said common analyte;
iii. wherein each said SMPCS-IDG assay comprises n number of SMPCS assays;
iv. wherein each said SMPCS assay is designed to exhibit a substantially identical response level to said common analyte;
v. wherein m is an integer of at least 1 and n is an integer of at least 1;
vi. wherein if m equals 1 then n is greater than 1 and if n equals 1 then m is greater than 1; and
vii. wherein m and n are not required to be the same value and n is not necessarily the same value for each m; and
b. obtaining an SMPCS reading from each said SMPCS assay in each said SMPCS-IDG;
i. wherein there are n number of SMPCS readings for each of said m number of SMPCS-IDG assays.
2. The method according to
3. The method according to
4. The method according to
5. The method according to
6. The method according to
7. The method according to
8. The method of
a. creating a calibration dataset by running multiple samples of known concentrations of said common analyte at different concentrations and
b. recording for each of said multiple samples of known concentrations of said common analyte:
i. said known concentration of said common analyte;
ii. said SMPCS readings from each SMPCS assay;
iii. said m number for said SMPCS-IDGs in the first assay;
iv. said n number for the SMPCSs in each SMPCS-IDG in the first assay; and
v. a list of classifiers for each SMPCS-IDG assay.
9. The method of
10. The method according to
11. The method according to
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13. The method according to
14. The method according to
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Description This application claims priority from the U.S. provisional application with Ser. No. 60/844,577, which was filed on Sep. 13, 2006. The disclosure of that provisional application is incorporated herein as if set out in full. The present invention relates to assays, specifically to intraplexing methods for improving the precision of suspended microarray assays. A number of patents exist for various forms of suspended microarray assays, including patents for substrate microparticles of various kinds, how their sets are differentiated, processing the array data and what is termed �multiplexing� of assays. A list of these references is submitted in an Information Disclosure Statement accompanying this application. A number of these patents are held by the Luminex� corporation, a company that produces specialized flow cytometers for use with microsphere based suspended microarray assays. Of those patents that cover multiplexing, none discuss the intentional use of more than one particle set targeted at the same analyte within a sample. None discuss how one might make use of a multiplicity of sensitivities to the same analyte by a set of suspended microarray assays in order to better determine analyte concentration. None disclose using a multiplicity of assays that should have the same sensitivity to analyte to improve precision. Nor do any of the listed patents discuss how both techniques (multiple identically sensitive assays and multiple differentially sensitive assays for the same analyte) can be combined together to achieve an even higher level of precision and repeatability. None of the patents discuss how such intraplexed assays can be used to eliminate instrumentation variances and make accurate estimates of true concentration of analytes without necessarily requiring calibration standards be run with every multi-well assay that is performed. To define intraplexing clearly, special terminology has been created because without it, experts became confused as to what exactly was being referred to. For this reason, a single particle (which is, for Luminex�, a microsphere) is called an SMP (suspended microarray particle.) A set of microspheres that are all labeled with the same classifier is called an SMPCS (suspended microarray particle category set). (Hence, SMPCSs is the plural form of SMPCS.) These two differentiations are all that is necessary for understanding suspended microarray systems. An SMPCS corresponds to what Luminex� commonly calls �a microbead region�, a �microbead set� or more colloquially, �a microbead� and is usually interchangeable with �bead number�, since Luminex� classifies their beads to users by numbers from 001 to 100. A method of classification of such sets will sometimes be referred to herein as a �classifier.� Intraplexing also introduces a superset, which is the �suspended microarray particle category set�identical group,� or SMPCS-IDG. (Likewise SMPCS-IDGs is the plural form.) In an SMPCS-IDG, a set of differently numbered microparticle sets are all coated with the same reagent(s) so as to make them identical in sensitivity to the analyte being assayed. Bearing this introduction in mind, these terms are discussed in more detail below. A suspended microarray system uses a population of suspended microarray particles (SMPs), all of which have one assay on their surface. These SMPs are run through a flow cytometer after running an assay protocol. The flow cytometer has a flow cell which differentiates individual SMP events as they go by. Thus, the result is a statistical sampling of the population of the SMPCS made up of individual readings. These individual event readings are not identical, but are distributed in an approximate normal curve. Conventionally, most of these SMP-based assays use fluorescent reporter molecules to provide a signal, but there are other methods. If multiple SMPCSs are present in a well, then more than one analyte can be assayed simultaneously in the same assay plate well. This is termed multiplexing of assays, and it is a primary selling point for current suspended microarray systems. A multiplexed assay comprises different suspended SMPCSs�where each SMPCS has an assay for a different analyte, and the SMPCSs are mixed together in one test tube or assay plate well. Conventional assay plates currently contain up to 96 wells in one plate, wherein each well contains fluid to be assayed, as shown in prior art Another assay method is an environmental assay method sometimes known as �smart dust� which consists of a tiny electronic chip, (that can be microscopic) that has an assay built into it, generally on its surface. This assay device usually receives energy from the environment in the form of sunlight, or from a reader device in the form of microwaves. The device acts as a transponder, sending the result of the assay to the reader device. Some of these devices work in fluid, while others broadcast the particles (�smart dust�) over a region which may be outdoors. These broadcast assays indicate to the reader what is present in the environment. There are many identical copies of each assay particle in a broadcast system, and the signals returned can be analogous to signals returned by microspheres in a flow cytometry system, having many separate readings for the analyte that are combined to produce one value. In an environmentally broadcast assay system of this kind the equivalent of the test tube or well in a plate is the responding region containing particles that fall within an area the reader can detect. As the reader is moved, this area changes as particles are added on the leading edge of movement, and lost on the trailing edge. Totalizing of readings for a region can occur by making arbitrary distinctions between one such region and the next. In this type of system, as with fluid suspensions, a set of SMPCS assays could be created where each assay reacted to the same analyte. The results could be collated and processed in an analogous manner to that of intraplex assays taking place within a fluid medium. One typical flow cytometry system for reading assays is the Luminex� system. To compensate for highly fluctuating readings, it is necessary that multiple wells be replicated for identical samples so that any variation may be seen. Typically this is done with two wells containing identical analyte samples, but this is of little statistical significance, because the �student t test� (hereinafter either �t test� or �t values�) value for a sample of just 2 has a multiplier of more than 60 on the standard deviation (at 99% confidence level) to get margin of error as shown in In multiplexing, the primary problem with using radically more SMPs for each SMPCS is that when assays are multiplexed there will be a statistical distribution of SMP counts obtained for each SMPCS in the multiplex. Theory predicts this effect, and experiment confirmed it. Thus it was found that to get a fairly reliable number of SMPs for each SMPCS when they are multiplexed an increasing number of SMPs for each SMPCS needs to be put into each sample well. This number of SMPs per SMPCS rises nonlinearly with the number of SMPs one attempts to collect for each SMPCS. In order to explain the problem better, an illustrative metaphor will be used of a swimming pool filled with M&Ms of different colors. In this example, the swimming pool is analogous to a single-sample well, and one M&M is analogous to an SMP. The populations of M&Ms that are of the same color are analogous to an SMPCS. For this thought experiment, a swimming pool filled with M&Ms of 100 different colors is considered. An equal number of M&Ms of each of 100 colors is present and it is assumed the M&Ms are randomly mixed having no artifacts such as differential density of one color M&M leading to concentration at the bottom or top. A barrel of M&Ms is randomly scooped from the random assortment in the pool, and from the barrel, a large coffee can full of randomly scooped M&Ms is taken. Finally, all M&Ms in the coffee can are thrown high into the air, and those that land within an arbitrary 6-foot diameter circle are categorized. This 6 foot diameter circle corresponds to what is read by a flow cytometer that is able to categorize by color. What will be seen from the above thought experiment is that there will not be an equal number of each color of M&Ms in the 6-foot circle. If one collects the counts of each color, and then categorizes them into a histogram with 5 to 20 different bins, plotting number of M&Ms in the histogram bin on the X axis against number of M&Ms per color for each bin, what would be seen is an approximation of a multinomial distribution of counts. Assuming the coffee can holds approximately 50,000 M&MS, What this multinomial distribution graph shows is that for about 30% of the colors, the number of M&Ms for each color will be near 500. But for some the counts will be much higher, and for some much lower. See In the case of the Luminex� flow cytometer, we know that the above �trial� will be repeated many thousands of times in the lifetime of an instrument. Understanding the statistical problem encountered in the swimming pool thought experiment makes the problem of SMPCSs in a multiplex assay easier to understand. One Luminex� instrument, the new FlexMAP 3D� can differentiate up to 500 different microsphere classifiers. If one were to create a multinomial simulation graph for that many microsphere classifiers, the outliers would be farther to the low and high regions of the graph. The intent of Luminex� in raising the number of classifiers is to allow the development of very highly multiplexed assays. However, if this capability is used, then it will show this distribution of counts problem even more than the current system that relies on 30 to 100 SMP reading events per SMPCS. It will require huge numbers of SMP's per SMPCS to work reliably. There is thus a need to improve the precision of such assays without replicating samples, and to compensate for the multiple stochastic and non-stochastic sources of errors. It is therefore a primary object of the invention to improve the precision with which each analyte can be read in any type of suspended array assay system by using a plurality of SMPCS readings for each assay. It is a further object of the invention to provide a method to compensate for the multiple stochastic and non-stochastic sources of errors that can occur in this type of assay system. It is a still further object of the invention to make possible statistically significant results from assays applied to single well samples. Since there is no statistical significance to a single result, (see It is a still further object of the invention to make possible processed readings that have high correlation between instruments, even if the instruments have significantly varying responses to identical stimulus. Experiments have shown that instruments can vary significantly when reading exactly the same SMPCSs. Other objects and advantages of the present invention will become obvious to the reader and it is intended that these objects and advantages are within the scope of the present invention. This present invention provides a method for making readings from a single sample statistically significant in a reliable manner. The method can be applied to any type of suspended array assay systems that use a plurality of individual readings from small (generally microscopic) particles coupled to an assay. This invention combines multiple separately identified assays of one sample, wherein the multiple assays are for a single analyte. By elimination of outliers, averaging, taking secondary averages of averages, taking ratios of averages and ratios of secondary averages, this method makes highly reliable diagnostics possible. This method compensates for the multiple stochastic and non-stochastic sources of errors that can occur in this type of assay system. The Applicant's method provides more precise readings and diagnoses various errors in these types of assays. Potential sources of variance that can be compensated for include: variation in size of SMPs affecting strength of signal, carryover of SMPs between wells, and inter-instrument calibration differences (including response curve for varying concentrations of analyte by the complete opto-electronic system.) Another problem that can be addressed by this method is the distribution of varying counts per SMPCS that occurs due to stochastic variance in multiplexed assays. The advantages of the Applicant's system are that the system (1) increases the statistical significance of results from assays applied to single well samples, (2) makes possible compensation for multiple sources of error, (3) makes possible increased precision for each analyte, and (4) makes possible processed readings that have high correlation between instruments, even if the instruments have significantly varying responses to an identical stimulus. A first form of the Applicant's method is what is known as a first-order intraplex assay, in which there is a set of m SMPCSs assaying for the same analyte where the assays are titrated to give different responses to the same level of analyte. A second-order intraplex is also detailed. This is an m�n matrix in which m different SMPCSs with coatings titrated to give different response levels have n duplicated SMPCSs that should give the same response. Finally, a multiplexed intraplex example is detailed, in which intraplex assays are combined so that multiple different analytes can be assayed following the Applicant's novel method. The foregoing aspects and many of the attendant advantages of the invention will become more readily appreciated as the same becomes better understood by reference to the following detailed description, when taken in conjunction with the accompanying drawings, wherein: The Applicant discloses several intraplex embodiments and provides guidance for the method to be applied to other situations. Although it will be described in relation to suspended microarray assays using a typical 96 well assay plate which typically suspend particles in fluid before reading the result via flow cytometry, the method may be applied to a variety of different types of particulate based microarray assays using various numbers of samples. In such assays, an assay is bound to the particle surface, and a protocol is run that results in a signaling event such as fluorescence indicating presence of analyte. Such assays include microspheres, microbeads, magnetic microbeads, bar-coded microrods, and microtransponders. (�Smart dust� is the distribution of tiny assay devices coupled with miniature transponders, where the sampling is of the environment, and it can also make use of the intraplexing method.) It is not necessary that the physical or chemical method of assaying for a specific analyte be identical on each of the suspended microarray intraplex assays. It is only necessary that the end result be a predictable difference in response signal level for a given concentration of analyte for each of the m assays. For purposes of the patent application, the term �intraplexing� and �intraplex� shall refer to the execution of the applicant's method. An �intraplexed assay� is one in which the intraplexing steps as defined have been performed. An SMP is a suspended microarray particle. This is one particle, such as a microsphere, microbead, a microrod or some other microscopic particle assay device that can be suspended in a liquid medium, or broadcast over some area. An SMPCS is a suspended microarray particle category set. This is a population of a multiplicity of microscopic particles such as microspheres, microrods or some other microscopic assay device, (see SMP) which has a marker system to allow categorization of a set by a reader instrument. In the Luminex� system, this is done by using two different long wavelength fluorophores that are varied as to proportion so that the set of particles can be categorized. The resulting two-dimensional matrix has regions to which numbers are assigned and can differentiate up to 100 different categories. As stated above, the Applicant's methods apply to a variety of situations, such as that involving a new instrument able to differentiate up to 500 different categories. Finally, an SMPCS-IDG is a suspended microarray particle category set identical group. This is a multiplicity of SMPCSs (see SMPCS) all of which share an identical signal response level to a single analyte being assayed. The �mean of the set of n SMPCSs� shall refer to the average of all the SMP category sets (SMPCSs) in an intraplex that comprise an SMPCS-IDG. By extension, �means of the sets of n SMPCSs� shall be the plural form. The �mean of the set of m SMPCS-IDGs� shall refer to the average of all the SMPCS-IDGs in an intraplex that have different level of response titration. A �mean of the set of m SMPCS-IDGs� may use a set of one or more �mean of the set of n SMPCSs� as its input, where each �mean of the set of n SMPCSs� defines on of the m values used to calculate the mean of the set of m SMPCS-IDGs. �m ratios� shall refer to the set of ratios of mean of the set of n SMPCSs as numerator, over mean of the set of m SMPCS-IDGs as denominator, which are m in count. The �range of m ratios� shall be defined as the absolute value of each ratio to each of the other ratios in the set of m ratios. �SMP event readings� shall refer to the set of individual events detected by an instrument used to detect the signal(s) from a set of microparticles on which an assay has been attached. �SMPCS readings� shall refer to the processed results presented by an instrument system that is used to evaluate some signal (which could be some radio frequency, fluorescence or some other detectable physics) from a set of SMP events. Typically, this would be presented as an arithmetic mean, a median, a peak (which is analogous to mode) or something similar. A user may have a choice of which of the values presented by the instrument system they will choose to use. When user choice is allowed, all of the choices available are considered �SMPCS readings� if they are used. A user might wish to further process the set of available SMPCS readings into a single numeric value, and if this was done, that value would also be considered an �SMPCS reading�. �SMPCS value� is an alternative way to refer to a number representing the result of an assay for a sample of a population of microparticles, as detected by an instrument system. The term �classifier� shall refer to the code that is used to identify all of the SMPs within one SMPCS. By extension, the term �classifiers� shall be the plural for a multiplicity of SMPCSs. (I.e. in the Luminex system, these are numeric values from 001 to 100 that are based on the technology of varying intensity of two fluorophores.) A first embodiment of the Applicant's system shall be referred to as a first-order intraplex assay, in which there is a set of m assays for the same analyte. In this case a single copy of each assay is used (i.e. n=1). As shown in The preferred embodiment, a second-order intraplex is an m�n matrix in which m different SMPCS response titrations have n identical SMPCS assays, as shown in Note that it is not required that the number, n, of identical assays be the same for each of the m different response titrations. In summary, the intraplex method diagrammed in Additionally, a third embodiment, a degenerate second-order intraplex where m=1 containing only one set of n>1 (usually n will be >2, see Intraplex assays can be combined so that multiple different analytes can be assayed in this manner and is referred to as a multiplexed intraplex. For example, five different analyte assays, with each assay consisting of a 4 by 4 intraplex for each analyte could be combined. This combination would require a total of 64 SMPCSs, 16 SMPCSs for each intraplex assay. Intraplex assays can also be combined in a multiplex manner with single SMPCS assays according to current convention. The following relates to a preferred embodiment of the invention as shown in The physical embodiment of an intraplex assay system for placement of an assay on microparticle media for reading by an instrument comprises a plurality of SMPCS assays, each providing a separate reading and wherein each reading is obtained in a manner standard for the instrument normally used to read it. This plurality of assays comprises a number (m) of SMPCS assays targeted at a common analyte wherein each SMPCS assay has a different response level to said analyte when said SMPCS assay is conducted. There are also n SMPCS assays that are copies of each of the m SMPCS assays, where each of the n copies is designed to show identical signal level for a given level of analyte. Finally, both m and n may be an integer of at least 1, m and n are not required to be the same, and the n for mp is not required to be the same as the n for mq where q and p are subscripts, each identifying an mi group of SMPCSs. (I.e. an intraplex may have 5 identical copies of one response level and 4 identical copies of another.) In typical operation, any SMPCS assays are added into a standard well in an assay plate, or to another test-tube analogue. The assays are read by an appropriate instrument for the microparticle system this assay method is applied to. For some SMPCS assays this could be any flow cytometer, for others it may be best achieved by using a specialized flow cytometer optimized for a particular set of identification markers. These readings are interpreted by software that is informed of how reading sets should be grouped for each intraplex assay. The software may have pre-set calibration response curves and margins of error for each intraplex assay as defined by the manufacturer. The software performs appropriate statistical processing on the set of intraplex readings, and returns a set of values to the user of the software, which represents the intraplex assay results. These results may be correlated by the software with a range of concentrations for the analyte in question. Software is not strictly necessary, it is a convenience. Analysis may be done by hand, by spreadsheet, statistics software or some special-purpose software. The analysis results in either a reading showing a signal level, which is compared to some standard value range, or a concentration, such as picograms per milliliter interpolated from a standard curve. In an alternative embodiment of the invention, there is some flexibility in the three algorithmic processing steps. In step one, the algorithm for determining whether an individual reading of a set is an outlier can vary. In step two, the averaging method used may not be a simple arithmetic mean, but instead one of a variety of other methods for determining an average, such as arithmetic mean, geometric mean, harmonic mean, or quadratic mean. All of them can be used to produce different numerical results that can then be used, as long as they are used with appropriate consistency. In step three, ratios may be taken between the available averages. What is important is that the basic concepts are applied. A software developer may choose any variants they find useful, including elimination of a step. A fourth step may be performed that provides a concentration estimate for intraplex assays. Typically, a standard curve is made for each assay plate. As shown in For an intraplex concentration estimate, an assay developer can create a standard curve for the assay using several plates, each of which contains as many wells as possible for the standard curve. Instead of 5 or so titrations for which interpolation is done, a large number of titrations, perhaps as many as 90 or more could be made. These standard curve plates can be repeated as many times as the assay manufacturer deems useful to ensure reliable results. Such a standard curve plate or plates can be run for each batch lot of intraplexed assays, and generally would be as a quality control method. Note that in this way it is not strictly necessary that a manufacturer replicate each of m response levels precisely, since they would recalibrate their assays for each batch lot. The developer can then define estimated concentration of analyte and margin of error by correlating known concentration with such features as the range of m ratios, fitting curves to the ratios by numerical methods or derivatives of the curves fitted, when ratios are graphed as points where the y coordinate is the ratio and the x coordinate is a useful value selected by the developer for each of the m ratios. For instance, given a set of m ratios as shown in An additional method that could be used for estimation of concentration of analyte is clustering of ratios using a K nearest neighbor algorithm or a neural net system. In K nearest neighbor, the ratios are used as N dimensional vector sets. This transformation into an N dimensional vector set can be done in a variety of ways which would be up to the software developer. Each vector set defines a point in N dimensions, and is then assigned a meaning value. The meaning response value would be a concentration. When a new vector set is supplied to the system, it also defines a point in the N dimensional space. The algorithm then returns the nearest neighbors as limited by a value, d, which is a maximum distance in the N dimensional space for any responders. The response is composed of a set of meaning values, each paired with vector distance from the new value. This allows an interpolation to be performed using the meaning values. Example of a K nearest neighbor system (Knns) in use. For this example we will use a simple 2 dimensional plane with x and y coordinate axes. The Knns is �trained� by supplying it a series of 4 vector pairs. These are: |{1,0}, {2,1}, {3,1}, {4,2}|. These four pairs are assigned meaning values of: {0, 5, 7, 10} respectively. To use the Knns a pair of numbers is supplied, {3,2} using a distance, d, of 2. The system would then find the points within a circle of radius 2 from {3,2} and return three value pairs consisting of: {meaning value, distance}|{5, 1.4} {7,1} {10,1}|. This is because the point {3,2} is a distance of 1.4 from {2,1}, and a distance of 1 from both {3,1} and {4,2}. This calibration dataset from the developer can be supplied with an assay kit so that estimation of concentration from intraplex results can be performed either manually by the user, or by software. It might be desirable for an assay manufacturer to automatically download calibration datasets into intraplex interpretation software based retrievable by assay lot identifier. It has been determined that intraplex assay results are highly stable from instrument to instrument, and can even compensate for variability in sensitivity of a single instrument over one assay plate. Consequently, intraplex assays do not necessarily require the use of standard fluids and standard curves on every plate to determine concentration of analytes. This provides opportunities for logistical improvement in certain diagnostic tests. Where standard curve methods are used for every plate of samples, intraplex derived concentration estimates can provide a crosscheck on the usual standard curve system. The intraplex invention has wide application for providing high precision assays that are typically read by flow cytometry. This type of assay is applicable also to assays such as �smart dust� and others that may not be suspended, but are instead distributed over some region to assay for analytes. The limit of the type of assay that this is applicable to is assays wherein the reading is made up of a collated set of readings from small particles. Those small particles may be of variable shape, and the particles have a means for providing a signal indicating the level of analyte detected. Now that the steps involved in the applicant's method have been adequately detailed, several example implementations of the steps will be described. For each of these examples, it is assumed that (1) there is no significance to the SMPCS classifiers selected being consecutive, only that they are different from each other, and (2) there is no theoretical reason why numbers of SMPCS classifiers would not be as many as 300 or more for a single intraplex assay in its entirety. To further explain point two, statistics indicates rapidly diminishing returns for larger numbers, but in physical terms limits are practical. The choices below are guided by what would be the low end numbers that statistically would show significant improvement in precision and reliability of suspended microarray assay systems. A simple first-order intraplex. Although this is not the preferred embodiment of the applicant's system, this example implementation is described first for purposes of simplicity. In this example, m=6, meaning 6 different SMPCSs are used. In the Luminex� system, microspheres are used for the SMPs, and one could select SMPCS 001, 002, 003, 004, 005 and 006. Using standard methods as described by Luminex�, some chemical, antigen, hapten, antibodies, or oligonucleotides are attached to the surface of the SMPCSs. For SMPCS 001, a chemical coating concentration is applied in the reaction vessel that will occupy the maximum available binding sites on the SMPCS. For the second SMPCS, the concentration of the coating chemical is diluted so as to provide less than complete occupation of available binding sites. A typical dilution factor might be 2, 3, 10 or whatever is determined to work appropriately. Each SMPCS in turn is coated with a serial dilution such that the end result will be 6 SMPCSs, wherein each of the 6 SMPCSs is coated so that they should give different signal level response to the same analyte. After the coating steps are complete, the SMPCSs are combined together and injected into the assay plate well so as to provide the same number of SMP's for each SMPCS (for instance, if there are 2000 of SMPCS identifier 001, then there are 2000 of SMPCS identifier 002, etc.) Each SMPCS will present a distribution of readings. In the Luminex� system, a variety of information is presented to the user, including mean and trimmed mean, peak and trimmed peak, (which are similar to mode) and median and trimmed median. It is often recommended to use median. In practice, it makes little difference which is used as long as the choice is consistent. Whichever value is chosen for use, that value becomes the reading from the instrument for the SMPCSs. A first order intraplex-average (mean of the set of m SMPCS-IDGs, where in this case n=1 for each m SMPCS-IDGs is then calculated from the 6 SMPCS values. After this, 6 ratios are then taken with the SMPCS reading as the numerator and the master average (mean of the set of m SMPCS-IDGs) as the denominator. A second order intraplex. In this preferred embodiment and example, m=4 and n=5, meaning 20 SMPCSs are selected. In the Luminex� system, microspheres are used for the SMPs, and for purposes of this example one could select SMPCS 001 to 020. The SMPCSs are then divided into 4 subsets of 5 SMPCSs each. (Each set of 5 will be an SMPCS-IDG.) For each of the 4 subsets of 5 microspheres, all 5 microsphere sets are combined in a reaction vessel. Using standard methods as described by Luminex�, some chemical, antigen, hapten, antibodies, or oligonucleotides are attached to the surface of the microsphere sets. For the first identical group subset of 5 SMPCSs, (first SMPCS-IDG) a chemical coating concentration is provided in the reaction vessel that will occupy the maximum available binding sites on the SMPCSs. For the second subset of 5 SMPCSs, the concentration of the coating chemical is diluted so as to provide less than complete occupation of available binding sites. A typical dilution factor might be 2, 3, 10 or whatever is determined to work appropriately. The end result of this will be 4 subsets of 5 SMPCSs, (or 4 SMPCS-IDGs) wherein each of the 5 SMPCSs in a subset are coated the same, but there are 4 different subsets that should give different signal level response to the same analyte. After the coating steps are complete, the 4 subsets of SMPCSs (or 4 SMPCS-IDGs) are combined together and injected into the assay plate well so as to provide the same number of SMPs for each SMPCS. Each SMPCS will present a distribution of readings. In the Luminex� system, a variety of information is presented to the user, including mean and trimmed mean, peak and trimmed peak, (which peak values are similar to mode) and median and trimmed median. It is often recommended to use median. In practice, it makes little difference which is used as long as the choice is consistent. Whichever value is chosen for use, that value becomes the reading from the instrument for the SMPCSs. For each of the 4 identical group subsets of 5 SMPCSs in turn, (for each SMPCS-IDG) any outlier readings in the subset of 5 SMPCSs may be removed if desired. Then the remaining readings of the subset are used to generate a mean average. This will result in 4 identical group subset averages (4 �means of the sets of n SMPCSs�, one for each SMPCS-IDG). Since the assay subsets have varying signal strengths the subset averages will differ. An intraplex-average (mean of the set of m SMPCS-IDGs) is then calculated by taking the mean of the 4 subset averages. 4 ratios may then be calculated using the subset averages (means of the sets of n SMPCSs) as numerators and the intraplex-average (mean of the set of m SMPCS-IDGs) as denominator. A second order intraplex where n is not identical. In this alternative embodiment and example, the intraplex is determined similarly to that in example two above, with the exception that instead of all four subsets having 5 SMPCSs, each subset could have a different number of SMPCSs. For instance, subset A could have SMPCS classifiers 001, 002, 003, or 00 . Subset B could have SMPCS classifiers 005, 006, 007, 008, 009, or 010. Subset C could have 011, 012, 013, 014, or 015. Subset D could have classifier numbers 016, 017, 018, 019. (For this alternative embodiment, it is not necessary that all of the subsets have a different number of SMPCSs, only that they are not all required to have the same number.) There are various reasons why an assay developer might want to make use of different numbers of beads. One reason might be that a higher degree of precision might be desirable for lower sensitivity SMPCSs compared to higher sensitivity SMPCSs since for a lower level of reporter signal the signal to noise ratio is lower, and hence a larger number of SMPCSs for that SMPCS-IDG makes sense. Additionally, there might be considerations of simple pragmatism, trying to use fewer SMPCSs, so that a multiplex of intraplexes will fit into the available SMPCSs for the instrument. Or there might be other practical reasons why using an optimum number of SMPCSs might not be reasonable. However, in every other way, the data is processed as in Example 3. A degenerate second-order intraplex. In this alternative embodiment and example, m=1 and n=5, meaning 5 SMPCSs are used. In the Luminex� system, one might select SMPCS 006, 007, 008, 009 and 010. The 5 SMPCSs are then combined in a reaction vessel. Using standard methods as described by Luminex�, some chemical, antigen, hapten, antibodies, or oligonucleotides are attached to the surface of the SMPCSs. This will ensure that all five SMPCSs are coated the same. After the coating steps are complete, the SMPCSs are injected into the assay plate well so as to provide the same number of SMPs for each SMPCS. Readings for each SMPCS are then collected as in previous examples. Following collection of readings, a decision is made as to whether to eliminate any outlier SMPCS readings in the set of 5. Then, the average of the remaining readings is taken. The average is the reading that would be used instead of the current single SMPCS value of the instrument. While the invention has been described in connection with specific embodiments thereof, it will be understood that it is capable of further modifications and this application is intended to cover any variations, uses, or alterations of the invention following. In general, the principles of the invention and including such departures from the present disclosure as come within known or customary practice within the art to which the invention pertains and as may be applied to the essential features hereinbefore set forth and as follows in the scope of the appended claims. Patent Citations
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A viral website for the upcoming Sony Pictures adventure Battle: Los Angeles has been released online at UnidentifiedEnemy.com. The site reveals an enormous amount of information about the attacking aliens in the movie. Click on any of these new photos below to access our full gallery from the viral site:
You can also click on the Alien Bilogy tab to learn about the aliens' Language and Bio-Mechanics and the Transportation section offers information on how they travel on both the ground and the water. The Weapons area gives us more details on their mines and other weaponry. All of these sections feature a computerized voice guiding you through this information. You can also click on small white boxes featured over a specific area to learn even more about that object.
to visit this new viral site and learn more than you ever thought you'd know about the aliens of Battle: Los Angeles.
Battle: Los Angeles was released March 11th, 2011 and stars Aaron Eckhart, Ramon Rodriguez, Cory Hardrict, Gino Anthony Pesi, Ne-Yo, James Hiroyuki Liao, Bridget Moynahan, Noel Fisher. The film is directed by Jonathan Liebesman.


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A perfect round up of fun activities and DIYs to help keep those kiddos occupied this summer. These ideas are great for those days you wonder to yourself "Why don't we have year round school?"
Read more from Melanie on You Are My Fave. Join Melanie on Facebook and Twitter for updates.


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Rafa still a work in progress at U.S. Open
Updated: September 3, 2010, 4:46 PM ET
Stephen Tignor, TENNIS.com
The courts of Flushing Meadows aren't ideal for Rafael Nadal, and based on early results, it will take a one-of-a-kind effort for him to win this tournament.
Was there something a little different about Nadal in his first-round match at the Open? Yes, there were the glowing yellow sneakers, the Darth Rafa all-black look and the clean-cut hair. But that's all part of the New York game. What about Rafa's game?
There was something new going on there, too. Nadal won fast-court ...
Read full story
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Villas-Boas rules out Damiao return
Andre Villas-Boas defended Tottenham's transfer window policy and practically ruled out returning with another bid for Internacional striker Leandro Damiao.
Villas-Boas made Damiao his top January transfer target but, despite a last-ditch attempt, Spurs failed to land the 23-year-old before Thursday night's 11pm deadline.
Chairman Daniel Levy's failure to sign Damiao means Jermain Defoe and Emmanuel Adebayor will be Tottenham's only recognized senior strikers for the rest of the campaign, and the latter may not be available for up to another two weeks as he is away at the African Nations Cup.
Internacional claimed they did not let Damiao leave for White Hart Lane because Spurs' offer, reported to be £13million, did not meet their valuation of a player who has 14 caps for Brazil and was top scorer at the Olympics.
Villas-Boas admits being left with two strikers is a "risk", but brushed off suggestions the club should have pushed the boat out to sign Damiao.
"We've approached this market very sensibly," the Tottenham manager told a press conference.
"I've said in our conversations that if (the Damiao bid) was going to go out of proportion, we would step out of it.
"We have made it public before that he is a player that we chase, but we couldn't agree on the full conditions so we've moved on."
Tottenham, who have a club partnership with Internacional, were expected to renew their interest in Damiao this summer, but Villas-Boas claims that is now unlikely.
"No I don't think (it will happen in the summer)," Villas-Boas said. "It's probably finished now."
Levy has become famed for his love of a last-minute deal in the window. He landed Rafael van der Vaart in the dying minutes of the summer window in 2010 and he left it late to capture Clint Dempsey last August.
But his failure to land Villas-Boas' top two targets in the past two windows - Damiao and Porto's Joao Moutinho - has left some fans unhappy.
Villas-Boas, who added Zeki Fryers and Lewis Holtby to his ranks last month, remains convinced his squad can finish in the top four this season, however.
"The fans' concerns are made by opinion-making and media expectations, so it's a roller coaster and it's more difficult for them to take," the Portuguese said.
"If this window hadn't opened, we sit fourth with the squad that we started the season with and you look pretty comfortable where you are. We are as we stand."
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Mark Birrell to take up Infrastructure Australia chairmanship
PUBLISHED: 05 Apr 2014 02:16:53 | UPDATED: 06 Apr 2014 12:41:27PUBLISHED: 05 Apr 2014 PRINT EDITION: 05 Apr 2014Port of Melbourne Corporation chairman and former Kennett government minister Mark Birrell will replace Sir Rod Eddington at the helm of Infrastructure Australia.
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People | Rod Eddington, Mark Birrell, Tony Abbott, Michael Deegan, Joe Hockey |
Topics | Infrastructure, Politics /Federal Politics |


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Things to see and do - Martinique
Leaving for Martinique
Nearby hotels
Hotel Bakoua Martinique from145 €
Book -
Karibea Squash Hotel from90 €
Book -
Karibea La Valmenière Hotel from119 €
Hôtel Frégate Bleue :
Nearby tourist sites
Hôtel Frégate Bleue
Hôtel Frégate Bleue
Address : Frégate EST 4 F - 97240 Le François
from : 120 EUR
Standing 5 minutes' drive from the centre of Le François on the eastern end of Martinique, this hotel features an outdoor pool. Free Wi-Fi and a daily breakfast are provided. Beautiful antique Creole furniture decorates each room at Hôtel Frégate Bleue. Views of the sea, a kitchenette and air conditioning are all available. Guests of the Frégate Bleue can relax or enjoy breakfast outside, surrounded by birds and tropical flowers. Tourist information is also offered. Carrefour Market is 5 km from the hotel. Rhum la Mauny is 30 minutes' drive away.
Useful Information
- Address : Frégate EST 4 F - 97240 Le François97240Le François
Main services
- Restaurant
- Air conditioning
- Non-smoking rooms
- Internet