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Despite spending more than $356 million over 10 years, the Justice Department's program to replace outdated radios for tens of thousands of federal agents has not achieved its initial goals and its future is uncertain, according to a new report from the Justice Office of Inspector General.
The Integrated Wireless Network was conceived in 2004 as a plan to replace old and deteriorating Land Mobile Radio systems with an interoperable radio network for Justice enforcement agencies. The network was to be used by agents of the Drug Enforcement Administration, Federal Bureau of Investigation and the U.S. Marshals Service, among others.
Related stories:
Justice Department asks for 2 percent increase in fiscal 2012
GAO: Departments drop major radio project
The program expanded to include 81,000 agents nationwide at a cost of about $5 billion, including agents from the Homeland Security and Treasury departments.
However, plans for the interoperable network and radios have been revised several times due to funding limitations and uncertainty. DHS dropped out in 2008.
Overall, the IWN program has not been effective at fulfilling the radio communication modernization, interoperability and spectrum efficiency needs of Justice, states the report, which is dated January 2012. Some details have been redacted by the inspector general's office due to law enforcement sensitivity.
"As a result, the department's law enforcement components are still using old and often obsolete equipment," the report concluded. "There is limited interoperability between the components and with other law enforcement agencies. The IWN program continues to struggle with funding limitations that have resulted in multiple revisions to the plan and a significant reduction in the planned nationwide implementation."
In addition, Justice has not been successful in meeting a Commerce Department directive from 1993 ordering that federal agencies reduce spectrum use by half by 2008, the report said.
"The department planned to comply with this mandate as part of the Integrated Wireless Network program's Land Mobile Radio system upgrade," the inspector general wrote. "However, three years after the conversion deadline, insufficient program funding and logistical problems continue to negatively affect the department's ability to comply."
To date, the effects of noncompliance have been minimal, the report added.
Under a revised agreement adopted by Justice, DHS and Treasury in 2008, the cost of deploying the integrated wireless network was projected at $1.2 billion over six years.
In 2009, Justice implemented the first phase in the Washington, D.C. region. However, funding cuts have limited additional deployments and will necessitate further revisions to the plans, the report said.
Moving forward, Justice officials should explore possibilities including 3G and 4G Long Term Evolution mobile technologies along with the National Public Safety Broadband Plan, the inspector general suggested.
"Many believe that Land Mobile Radio systems will be replaced by some type of secure broadband system. However, technology that will fulfill the needs of law enforcement agencies has yet to be refined," the report said. "There is still a need for an improved communications system, and while IWN may no longer be the best solution, a solution is desperately needed."
About the Author
Alice Lipowicz is a staff writer covering government 2.0, homeland security and other IT policies for Federal Computer Week.
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President Obama's proposal to boost government coordination with the private sector got a warm welcome in the House Homeland Security Committee.
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Meet the women and men who are doing great things in federal IT.
The law's certification and approval provisions empower CIOs to end outdated software development projects, says Agilex's Roger Baker.
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FCW investigated efforts by the departments of Defense and Veterans Affairs to improve a joint data repository on military and veteran suicides. Something as impersonal and mundane as incomplete datasets could be exacerbating a national tragedy.
Despite delays, the program is at a critical point for determining the ultimate impact of cloud technology in the government space.
In an interview with FCW, the Department of Veterans Affairs' chief technology officer talks about overhauling the digital experience for VA customers.
The National Information Exchange Model's usefulness extends far beyond its origins in justice and law enforcement.


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Not too long ago, we were lucky have Ristretto Roasters out at the grand opening of our Portland store to provide a tasting of some of their fabulous coffee. While they were in we got to chat with them about…
Java Talk: Zoka Coffee Chemex Demo
by Brenna • • 1 Comment
Continuing on our tour of local roasters, we recently visited Zoka Coffee in Ballard, Washington. While we were at the roastry, we were lucky enough to have our friend David brew up some Zoka coffee on a Chemex for us.…
Java Talk: Water Avenue Chemex Demo
by Brenna • • 0 Comments
The grand opening of our Portland store this past weekend was a great success! We had a great turn out and had a wonderful time meeting all of you. Thank you so much for your support. Besides getting a chance…
Java Talk: Caffé Lusso Chemex Demonstration
by Brenna • • 0 Comments
We recently had the pleasure of hosting Mike Smith from the Redmond, WA based roaster Caffe Lusso. The brand was started in 1999, when roastmaster Philip Meech realized how easy it was to find a bad cup of coffee even…
Barista Snapshot: Bethany at The Fresh Pot
by Sam • • 0 Comments
Brewin' with Brandi: Coffee Gelee Recipe
by Kat • • 0 Comments
Do you think you're ready for this gelee? We think you are! If you're in the market for a super fun and fairly simple coffee-infused dessert, this recipe is a great choice! In addition to having fun while you make…
Barista Snapshot: Jake at SteamDot Coffee
by Sam • • 0 Comments
SCG Crew's Favorite Gear: Kettles, Pour Overs, Press Pots, Coffee Makers, Oh My!
by Kat • • 0 Comments
You know that we play with a lot of different types of coffee equipment here at SCG and the crew definitely has their faves! We asked for volunteers to share which gear they dig in different product categories. Watch as…
Chemex Cold Brew
by Kat • • 0 Comments
We're finally experiencing the joy of summer (!!) and there's no better way to rock it than with a tall glass of cold brewed coffee in your hand. Jessica's favorite brew method is the Chemex, so we asked her to…
Crew Review & Comparisons: Kalita Wave Pour Over
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It's a big bad mama jamma of a Kalita-related blog entry! So, we went a little Kalita wild last week — trying this popular pour over out for the first time, then comparing the different filter material types and how…

subset: commoncrawl


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Product Description
Size GuideThis design is one of Banksy's highly amusing sticker series. It has also been known as "Kids With Guns" sticker but the Jack & Jill angle is more Banksy… we believe!?
Printed on super soft, fairwear cotton and made to last.
Although most people can afford one of these stickers, it also looks great on a t-shirt!


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Fluor Awarded Contract For Udokan Copper Project In Russia
Fluor Corporation (NYSE: FLR) announced today that it was awarded an initial contract by Baikal Mining Company (as part of METALLOINVEST) for the definition phase of the Udokan copper deposit development project in Russia. Fluor booked the undisclosed contract amount in the third quarter of 2012.
Baikal Mining Company commenced work on the definition phase study with Fluor Canada Ltd and it is expected to continue through the remainder of 2012. The start of feasibility study services is anticipated for first quarter 2013 and last for approximately 12 months. The work is being executed from Fluor's Vancouver, Canada office with support from the Farnborough, United Kingdom and Moscow, Russia offices.
"This is a strategic win for Fluor in this key region," said Rick Koumouris, senior vice president and Fluor's Mining & Metals business line lead. "We are glad that our customer recognized the value of our diverse global mining experience as well as our world class safety culture that will help them accomplish this project."
During the definition phase, Fluor will develop and perform a metallurgical test work program, and will implement the trade-off studies required to prepare design criteria and scopes of work for the subsequent stages of the international feasibility study for the Udokan copper project.
The Udokan deposit, situated in the Kalarsky Area of Russia's Zabaikalye Region, is one of the largest undeveloped copper deposits in the world. Baikal Mining Company was established in 2008 specifically for the implementation of the Udokan copper deposit development project. Alisher Usmanov's USM STEEL & MINING Company which owns 50 percent of the shares is the major shareholder in METALLOINVEST Company. Other major shareholders are Vladimir Skoch's Seropaem Holdings as well as VTB Bank which own 30 percent and 20 percent of the shares, respectively. About Fluor Corporation Fluor Corporation (NYSE: FLR) designs, builds and maintains many of the world's most challenging and complex projects. Founded in 1912, the company was started by John Simon Fluor Sr. with a modest investment of $100. Since those humble beginnings, the company has grown into one of the largest engineering & construction companies in the world. Fluor is celebrating its 100 th anniversary during 2012. Today, through its global network of offices on six continents, the company provides comprehensive capabilities and world-class expertise in engineering, procurement, construction, commissioning, operations, maintenance and project management. Headquartered in Irving, Texas, Fluor is a FORTUNE 200 company and had revenue of $23.4 billion in 2011. For more information, visit www.fluor100.com and www.fluor.com.Check Out Our Best Services for Investors
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Timo Polvinen
Road of Raate 1940
Road of Raate is located at Suomussalmi, Finland. At the beginning of 1940, there was a battle between Finland and Red Army. The battle at Road of Raate is known as one of the legendary battles at Winter War in Finland. Lead your team and destroy all Red Army tanks in the Haukila area using...
Application features: -Accident data (in Finland) -Weather information -Driving log -Personal placemarks -Moose warning tracks Map tiles are provided by the OpenStreetMap, MapBox and Microsoft Bing -services. Permissions: FULL INTERNET ACCESS Map tiles, outside temperature, ads, Google...
TrailCam Beta
TrailCam Beta is a motion detection Android application that can be used for taking pictures on a wildlife animals. Pictures are stored on SD card and can be sent by email. TrailCam can be controlled remotely by SMS messages. Known bugs: -Preview window not working after phone set to...
Few freeware wallpaper images from Finland for your Android phone.
Stalag Luft III 1942-1945
Stalag Luft III was a prison camp for Allied air crews during the World War 2. As a leader of a Special Operations team, your mission is to find the key and open the camp gate to release the prisoners. A web site: http://www.kaurismaa.com/games/stalag/ 17thMay2014 Some UI polishing Update:...
ETRSTM35FIN coordinate conversion to WGS84 Ported from CPAN package Matti Lattu: firstname.lastname@example.com http://search.cpan.org/~mplattu/Geo-Coordinates-ETRSTM35FIN-0.01/lib/Geo/Coordinates/ETRSTM35FIN.pm Conversion formulas: Python module from Olli Lammi http://olammi.iki.fi/sw/fetch_map/ Source...


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This car was featured in this video: http://www.youtube.com/watch?v=7FW0ZH9lMQA
@IForgotPassword if you dont know how to install ImVehFT then STFU and take some Advice at Mr.Google,i got the same problem with you,but i work hard to make it work,now i enjoy the mod with no more weird lamp color
Arman OssiLoko: try to use msvcr100d.dll and newOpcodes.cleo from the ImVehLM
mine works
IForgotPassword : what's wrong with you?
this car works even though you don't install IMVehFt
@Arman OssiLoko That's because Improved Gay Lights mod
My game crashes when I install it. After it crashed, I went to download DKK2PC that imVeh or whatever it was called. Installed DKK2PC's mod too but it crashed again. What's wrong?
epic mod! 100/100
I'm not sure is it my game or what? but the interior of the car is bad.... can you help me fix this problem??????
VIDEO: http://www.youtube.com/watch?v=9pKtbz6NPeI
@IForgotPassword dafuq with you? STFU, stupid!
@jiry97 That's because Improved Gay Lights mod


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Kukla's Korner Hockey
Rangers Ready For A Run
by Paul on 02/14/07 at 05:40 PM ET
Comments (0)
fromm Pierre Lebrun of the CP via Yahoo,
Only seven points separate sixth-place Tampa Bay from the 11th-place Rangers with Carolina, Montreal, the New York Islanders and Toronto sandwiched in between and seven and half weeks to go in the regular season. The Rangers, who play at Carolina on Thursday night, feel they're primed for a run.
"I do feel that way. It's not just yapping, it's the real deal," Rangers head coach Tom Renney said Wednesday. "I've seen the way we've played in the last two weeks. If we were in the playoffs and they were starting tomorrow, I would feel very, very good about playing anybody."
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About Kukla's Korner Hockey
Paul Kukla founded Kukla's Korner in 2005 and the site has since become the must-read site on the 'net for all the latest happenings around the NHL.
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Hoag Memorial Hospital Presbyterian has rolled out Patient Care Technology Systems' Amelior EDTracker solution to enable patient tracking at the hospital's emergency department. Patient Care said the Web-based tracking tool features Sonitor Technologies' real-time locating system designed to make patient flow easier.
View Full Article in:
Healthcare Informatics onlinePublished in Brief:


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New day. New Daily Deals. Get them before they are gone!
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Item: 950043 Model: S90055
Shamrock Leaves/berries printed paper shopping bag has a pattern of alternating green leaves and black berries around the top edge. Shopping bag measures 5 1/2" x 3 1/4" x 8 3/8" and features twisted natural handles for comfortable grip.
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This Web site is intended for use by US residents only. See International Sites. See our delivery policy for full details. Copyright 1998-2014, Staples, Inc., All Rights Reserved.


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SodaMod: Save Money On SodaStream Refills With a Hacked Paintball…
One of the main reasons people love the SodaStream is that you save money by making your own sparkling water. Supposedly. Unfortunately, replacing those CO2 canisters is expensive. This clever hack will help you cut those costs by a huge margin.
Kid Gets Box of Porn and Viagra Instead of Paintball Gear
Christmas and/or Hanukkah came early for little Connor Whelihan, whose paintball order was replaced by a giant box of porn, Viagra, and "sex oils," the NY Daily News reports. Whelihan's now prepared for explosive warfare of an entirely different sort.
Paintballing and Nerf Combined to Make This Water Gun
Playing with xploderz looks like shooting paintballs only without the paint. Or the pain, even after flying at your target from 85 feet away. Check them out for anywhere from 15 to 70 bucks. [Amazon via The Awesomer]
All The Single (Legged) Ladies: If You Like It Then You Should Put a…
Filmmaker Rob Spence, famed for his camera eyeball implant, is looking for an eligible young woman. Who's missing a leg. So he can give her a paintball machine gun. That she will attach to her leg.
Automated Paintball Sentry vs. Little Brother: Not a Fair Fight
Click to viewLook, kid, I know you need to defend yourself. But a little plastic sword? You can't bring a knife to a gunfight. [Today's Big Thing]
Staring Down the Barrel Of an MK-19 Grenade Nerf Launcher
If you're someone who confuses paintball war with real war, you'll be verrrrry interested in this MK-19 belt-fed Nerf launcher. The DIY shoots 2.5 rockets/second, weighs 100 pounds, and guarantees that everyone'll want to be on your team. [UberGizmo]
Low Cost Robot On Wheels Can Spy Baddies, Paint Them to Death
Soldiers in Iraq Get 'Paintball Guns on Steroids'
Apparently, the new weapon against insurgents in Iraq is a paintball gun. Mind you, it's a paintball gun that uses paintballs full of a mixture of paint and the brittle metal bismuth, and it's a paintball gun that fires at 900 PSI compared to the standard 300-500 PSI, but it's a paintball gun all the same.
A Rommel-wannabe from Kettering University in Flint, Michigan, has built a fully working, 1:2 scale version of the Tiger I 56.9-tonne heavy tank used by the Wehrmacht in World War II. Not happy with that, he drives his amazing creation—Guderian-style—on the road, with a "yellow triangle" on the back. The thing is so…


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Boxed Kitchen Tool and Gadget Set
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Conference Paper
A Novel Knowledge-driven Systems Biology Approach for Phenotype Prediction Upon Genetic Intervention.
Conference: International Conference on Bioinformatics & Computational Biology, BIOCOMP 2010, July 12-15, 2010, Las Vegas Nevada, USA, 2 Volumes
Source: DBLP
- Citations (0)
- Cited In (1)
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ABSTRACT: Generation of induced pluripotent stem cells (iPSCs) opens a new avenue in regenerative medicine. One of the major hurdles for therapeutic applications is to improve the efficiency of generating iPSCs and also to avoid the tumorigenicity, which requires searching for new reprogramming recipes. We present a systems biology approach to efficiently evaluate a large number of possible recipes and find those that are most effective at generating iPSCs. We not only recovered several experimentally confirmed recipes but we also suggested new ones that may improve reprogramming efficiency and quality. In addition, our approach allows one to estimate the cell-state landscape, monitor the progress of reprogramming, identify important regulatory transition states, and ultimately understand the mechanisms of iPSC generation.PLoS Computational Biology 12/2011; 7(12):e1002300. · 4.83 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.


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Blowout -our flagship event. Dates for 2015: May 29th to 31st. Tickets on sale from the end of February
Concerts See some of the best pipe acts from Britain, Europe and beyond.
Workshops Learn technique from experienced workshop leaders.
Sessions Join in with impromptu sessions.
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Makers A chance to buy pipes direct from the maker.
Instruments A chance to see, hear and play unusual bagpipes.
Talks Learn about the cultural history of piping.
Demonstrations Professional bagpipe makers explain the secrets of their art.
Festival set in and around the beautiful Polesworth Priory.
Camp inside the Priory's secluded garden and grounds.


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Town Square
Driving into the future
Original post made on Apr 3, 2013
Read the full story here Web Link posted Monday, April 1, 2013, 2:39 PM
Comments (1)
a resident of Danville
on Apr 3, 2013 at 12:34 am
I Will be impressed when County Connection starts running regular bus service to Blackhawk again on Tassajara. Amazing there is no bus service to such a large populace.
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Steve Glazer for State Senate
By Roz Rogoff | 2 comments | 1,509 views
Pleasanton resident will have his hands full trying to keep the Oakland teams
By Tim Hunt | 0 comments | 872 views


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Publications (41)78.36 Total impact
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ABSTRACT: In a survey of 105 populations of Cepaea nemoralis sampled in North Spain, the distribution of morph polymorphism seems to have a climatic component. The area sampled corresponds with the two main climatic regions in the Iberian Peninsula: Green and Brown Iberia, which have an Atlantic and Continental climate, respectively. Paler colour and banding phenotypes are found in the Atlantic zone, while the dark ones are commoner in Brown Iberia. This may arise from climatic selection related to behaviour patterns, which may be particularly important in limiting situations with harsh climates.Biological Journal of the Linnean Society 01/2008; 35(3):217 - 227. · 2.54 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Digital patterns of a sample of monozygotic and dizygotic twins were analyzed to obtain heritability values for the four basic types of patterns: arch, tented arch, loops, and whorls. Loops have been separated according to their orientation radial or ulnar. To carry out this study, we used the Holzinger and Clark indices. The results show highest concordances for monozygotic twins except for ulnar loops of the left hand and radial ones of the right hand. Different values of heritability were found for the right and left hands, with finger I having the highest values.American Journal of Human Biology 05/2005; 3(1):11 - 15. · 1.93 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: The present study involves the evaluation of digital dermatoglyphic traits of 2185 unrelated individuals (1152 females and 1033 males) from 17 natural valleys of the four Basque provinces (Vizcaya, Guipúzcoa, Navarra, and Alava) in the Spanish Basque Country. Univariate intervalley and between-sex comparisons were carried out by means of chi-square contingency analysis for pattern types and by means of one-way analysis of variance for ridge counts. Multivariate intervalley comparison was carried out by means of correspondence analysis for pattern types and by principal component analysis for ridge counts. The results of this study are notable for the following findings: (1) in general, all variables are significantly heterogeneous among valley populations; (2) there was a greater differentiation among the valley populations than between sexes in one valley population; (3) affinities among the intervalley populations depend on the variables considered; (4) the valley populations from Vizcaya resemble those from the Pyrenees; (5) based on interprovince comparisons, the Vizcaya and Navarra samples are the closest: (6) in general, the valley samples from Alava are the worst clustered; (7) the universality of dermatoglyphic component structure fits better in males.Human Biology 05/2003; 75(2):265-91. · 1.52 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Fragile X syndrome is associated with an unstable CGG repeat sequence in the 5' untranslated region of the first exon of the FMR1 gene. The present study involved the evaluation of factors implicated in CGG repeat stability in a normal sample from two Basque valleys (Markina and Arratia), to discover whether the Basque population shows allelic diversity and to identify factors involved, by using the data in conjunction with previous findings. The study was based on a sample of 204 and 58 X chromosomes from the Markina and Arratia valleys, respectively. The CGG repeat, the AGG interspersion and two flanking microsatellite markers, FRAXAC1 and DXS548, were examined. In the Markina valley, gray zone alleles (> or =35 CGG repeats) were associated with anchoring AGGs, with the longest 3' pure CGG repeats of the valley (=15), with the 5' instability structure 9+n and with one principal fragile X FRAXAC1-DXS548 haplotype 42-50. In the Arratia valley, gray zone alleles (> or =35 CGG repeats) showed the highest frequency among the Basque samples analyzed, and were associated with anchoring AGGs, with the longest 3' pure repeats (> or =20), with the 5' instability structure 9+n and with one "normal" FRAXAC1-DXS548 haplotype 38-40 (these data from Arratia suggest the existence of a "protective" haplotype). The results showed, on the one hand, differences between Markina and Arratia in factors implicated in CGG repeat instability and, on the other hand, a great similarity between the general Basque sample from Biscay and the Markina valley.Heredity 03/2003; 90(3):206-11. · 3.80 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Numerous studies have shown there is consistent evidence implicating genetic factors in the etiology of autism. In some cases chromosomal abnormalities have been identified. One type of these abnormalities is gaps and breaks nonrandomly located in chromosomes, denominated fragile sites (FS). We cytogenetically analyzed a group of autistic individuals and a normal population, and we examined the FS found in both samples with the aim of (1) comparing their FS expression, (2) ascertaining whether any FS could be associated with our autistic sample, and (3) examining if there are differences between individual and pooled-data analyses. Different statistical methods were used to analyse the FS of pooled and individual data. Our results show that there are statistically significant differences in the spontaneous expression of breakages between patients and controls, with a minimal sex difference. Using the method for pooled data, eight autosomal FS have preferential expression in patients and five patients were found to be positive at FS Xq27.3. With the method per-individual analysis, four FS emerged as specific in our autistic sample. Inferences of FS from pooled data were different from those of individual data. The findings suggest that although analysis of pooled data is necessitated by the problem of sparse data, analysis of single individuals is essential to know the significance of FS in autism.Behavior Genetics 12/2002; 32(6):397-412. · 2.84 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: The genotoxicity of atenolol, a beta-blocker antihypertensive drug, both in vitro and in vivo, was cytogenetically tested for its ability to induce sister chromatid exchange (SCE) and micronuclei (MN) in cultured peripheral lymphocytes. Also, fluorescence in situ hybridization (FISH) with a centromeric probe was performed to determine the origin of the induced MN. The in vivo study was carried out, on the one hand, on four patients under antihypertensive treatment with atenolol and, on the other hand, on four matched control individuals taking an oral dose of atenolol. The in vitro study was performed on the control individuals by adding the drug to the culture medium at a final concentration similar to the levels found in plasma. When a comparison was made, the frequency of SCE did not show significant differences in any case. A statistically significant increase in the frequency of MN was detected in patients but not in control individuals either in vitro or in vivo. FISH analysis revealed statistically significant differences between patients and control individuals without the drug with respect to the frequency of centromeric signals in MN. Taking all these observations together, our data suggest that chronic exposure to atenolol resulted mainly in the induction of chromosome loss, so an aneugenic activity could be predicted. Different sensitivity to the compound was observed among control individuals. Nevertheless, all of them responded to the presence of atenolol in the same way in both assays. Interindividual variability was also reported. The intervariability seen in patients suggested an adaptive response to the chemical after long-term therapy.Mutagenesis 06/2000; 15(3):195-202. · 3.50 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: The fragile X syndrome is an X-chromosome-linked dominant disorder with reduced penetrance. It is the most common inherited form of mental retardation. The molecular basis is usually the unstable expansion of a CGG trinucleotide repeat in the 5' untranslated region of the first exon of the FMR1 gene, which resides at chromosome position Xq27.3 and is coincident with the cytogenetic fragile site FRAXA, which characterizes the syndrome. In the Biscay province of the Basque Country the prevalence of FRAXA in a mentally retarded sample of non-Basque origin is in the range of other analyzed Spanish populations. In the sample of Basque origin we have not found FRAXA site expression and the repeat size is in the normal range. Based on this, we have examined FMR1 gene stability in normal individuals of Basque origin from the Biscay province. This study is based on a sample of 242 X chromosomes. The results from the CGG repeat region of FMR1 indicate that a prevalence of predisposing normal alleles toward repeat instability in the Basque population is 0.00% or near to it. This could be 1 of the explanations of the apparently low fragile X syndrome incidence found in the Basque mentally retarded sample analyzed by us. This low incidence does not seem to be associated with the flanking microsatellite markers.Human Biology 03/1999; 71(1):55-68. · 1.52 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Fragile X syndrome is the most common inherited form of mental retardation. The syndrome is associated with a CGG repeat expansion in the 5'UTR of the first exon of the FMR1 gene. This gene maps to Xq27.3 and coincides with the cytogenetic fragile site (FRAXA). The present study deals with the prevalence of fragile X syndrome among individuals with mental retardation of unknown cause from institutions and special schools from the Spanish Basque Country. Results of cytogenetic and molecular studies, performed in a group of 134 unrelated individuals (92 males and 42 females) are presented. The cytogenetic marker at Xq27.3 was identified in 12 patients. Other chromosomal abnormalities were found in two cases that this and previous studies confirmed as Angelman and Prader-Willi syndromes. Two males, in whom the cytogenetic marker was identified, were found negative for FRAXA and FRAXE expansion at the molecular level. The present study shows that the frequency of the FRAXA full mutation in individuals of Spanish non-Basque origin is in the range of other Spanish populations. In the sample of Spanish Basque origin we have not found cytogenetic FRAXA site expression, and the CGG repeat size of FMR1 gene is in the normal range. The significance of these results are discussed.Annales de Génétique 02/1999; 42(4):197-201. -
Article: a-b ridge count in a Basque population: fluctuating asymmetry and comparison with other populations.
[Show abstract] [Hide abstract]
ABSTRACT: We have analyzed the a-b ridge count and its fluctuating asymmetry in a sample (331 males and 290 females) from the Basque region of Alava province, Spain. Significant bimanual differences in the a-b ridge count are apparent only for females, and the sexual differences are significant for both hands. A comparison of the results in the Alava Basque population with results for other Basque populations showed sexual dimorphism. The results for fluctuating asymmetry do not support the hypothesis that if the regression of fluctuating asymmetry on the right and left hands is quadratic, the fluctuating asymmetry is a result of developmental homeostasis. Our data seem to indicate also that the factors that determine the a-b ridge count are canalized in females and males in the same way.Human Biology 03/1995; 67(1):121-33. · 1.52 Impact Factor - Cytologia 01/1995; 60(2):159-165. · 0.24 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Genetic and environmental prenatal factors influencing the fluctuating asymmetry of the a-b interdigital ridge count are examined. From the results obtained we can conclude that fluctuating asymmetry of the a-b interdigital ridge count is poorly influenced by genetic factors. We suggest that fluctuating asymmetry of dermatoglyphics provides a good measure of developmental stability in humans, especially for males. The results also indicate that random environmental factors, acting before the 19th week of embryonic development, could be related to the differential timing of maturation of the sexes.Annals of Human Biology 01/1993; 20(6):557-63. · 1.15 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Palmar dermatoglyphics of a sample including 552 males and 701 females from 8 Basque valleys were analyzed. We studied the frequency of palmar pattern types and compared them using correspondence the frequency of palmar pattern types and compared them using correspondence analysis. The results of this comparative study show that there is diversity among valleys and also that this diversity depends on the trait and on sex. Genetic drift could explain this variability found in the Basque population.Human Biology 11/1992; 64(5):705-16. · 1.52 Impact Factor -
Article: Effects of genetic and environmental factors on the a-b, b-c and c-d interdigital ridge counts.
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ABSTRACT: A study of 100 MZ (55 female and 45 male) and 97 DZ (50 male and 47 female) same-sexed twin pairs was carried out to analyse the genetic component of the variance of the a-b, b-c and c-d interdigital ridge counts by means of the Christian method. Especially for the a-b interdigital ridge count, we found it important to analyse both sexes separately. Our results suggest that the a-b count in males seems to be more influenced by environmental factors than the other counts. For females, the three interdigital counts seem to have a strong genetic component influencing their phenotypic expression. Factor analysis with VARIMAX rotation showed each interdigital ridge count to be genetically independent.Hereditas 02/1992; 117(2):189-94. · 0.76 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Different analyses of genetic polymorphisms performed on the Basque population have suggested a possible heterogeneity of the Basques and a singularity of their genetic characteristics. In this paper, both aspects are analyzed by means of the genetic study of seven polymorphic systems--ACP, ADA, AK, ESD, PGD, GC, and HP--in 854 autochthonous individuals from the province of Vizcaya. The individuals were classified as being from the regions of Arratia, Guernica, Durango, Uribe, Marquina, Lea, and Bilbao, on the basis of the birthplaces of their four grandparents. Analyses for heterogeneity of the gene frequencies distribution suggest that there is a moderate genetic heterogeneity, probably produced by centuries of geographical and administrative isolation of these regions. The comparison with caucasoid populations, performed using the principal components analysis and Cavalli-Sforza and Edwards arc distance, indicates that the subpopulations of the province of Vizcaya have experienced little genetic exchange with other caucasoids and that the distribution of their genetic frequencies differentiates them from other populations.The American Journal of Human Genetics 09/1991; 49(2):450-8. · 10.99 Impact Factor -
Article: Acid phosphatase, adenosine deaminase and esterase D polymorphisms in the Spanish Basque population.
[Show abstract] [Hide abstract]
ABSTRACT: The 3 red-cell polymorphic systems acid phosphatase (ACP), adenosine deaminase (ADA) and esterase D (ESD) have been studied in a random sample of 1,112 individuals from the Basque country: The allelic frequencies obtained were ACP*A = 0.275, ACP*B = 0.718 and ACP*C = 0.007; ADA*2 = 0.021, and, ESD*2 = 0.066. The allelic frequencies have been compared with those of other Basque and other European populations. In comparison with Basques, significant differences were detected only for ACP, whereas as regards other Europeans significant differences were obtained with practically all the populations compared for the 3 genetic systems studied. The low values of the less frequent alleles, especially that for the ACP*C allele which is the lowest reported in Europe, are noteworthy.Human Heredity 02/1991; 41(2):93-102. · 1.64 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Fluctuating asymmetry for the digital quantitative value was analyzed in a sample of twins (mono and dizygotic) and singletons. The aim was to check if the influence of twinning on the development is expressed in a higher fluctuating asymmetry in twins than in singletons. The results have shown that significant differences exist among the three groups studied, and these differences are fundamentally expressed when the radial and ulnar counts are considered separately.Hereditas 02/1991; 115(1):31-5. · 0.76 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Digital dermatoglyphics of a sample from the Basque Valley of Salazar, situated in the West of the Pyrenees, were analysed. The results showed bimanual differences in both sexes, and also sexual differences for both hands. The comparative study with other Basque valleys showed that, in spite of their supposed common origin, the geographic barriers and the isolation have generated a genetic/dermatoglyphic and linguistic differentiation.Annals of Human Biology 01/1991; 18(3):221-33. · 1.15 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Eighty-six females and 79 males from the Basque valley of Deba were analyzed with respect to their digital patterns using correspondence analysis. We found that there was a significant sexual difference for only one type of pattern, tented arch. Also, this population was compared with other Basque valley populations and with other Spanish populations. We found great variability among Basque subpopulations, despite their supposed common origin. Dermatoglyphic distances for some traits can be interpreted as genetic distances because there is high heritability of these traits. The results of the comparison between the Deba valley population and other Spanish populations showed that the Deba population is markedly distant from the other populations.Human Biology 09/1990; 62(4):553-72. · 1.52 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Cepaea hortensis (Mull) is found in Spain only in the western part of the Iberian mountain range. This is the southernmost limit of its range. The most frequent colour is yellow, brown being very rare. The most frequent band patterns are 12345, fused banded and unbanded. There are associations between maximum and minimum temperatures and pink and effectively unbanded yellow phenotypes. The populations may be grouped into two zones, one located in the north and the other in the south of the sampled area. Visual predation was not observed. The marginal populations studied by us were compared with others from Northern Europe, and it was observed that pink snails are more frequent at the southern limit, and unbanded ones at the northern limit. This was interpreted as a climatic selection.Genetica 07/1990; 81(2):109-115. · 1.75 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Digital dermatoglyphics of an indigenous sample of 87 males and 101 females from the Urola Valley in the Spanish Basque Country are compared with those from the nine other Basque valleys previously analyzed. In both sexes of the Urola Valley, there is a very high frequency of radial loops; the mean found in this valley extends the range of variation for South European-Mediterranean populations, and it is in the superior limit of all Caucasian populations. There are bimanual and sex differences in the frequencies of whorls and loops. Contrary to what occurs normally in populations, in the Urola Valley the frequency of whorls is higher in females and the quantitative value of digital patterns is lower in males. The results of this study show the existence of heterogeneity among valleys for digital trait frequencies and for finger ridge count, and this heterogeneity is more marked in females.Anthropologischer Anzeiger 04/1990; 48(1):65-84. · 0.54 Impact Factor
Publication Stats
231 | Citations | |
78.36 | Total Impact Points | |
Top Journals
- Human Biology (7)
- Annals of Human Biology (6)
- Heredity (4)
- Anthropologischer Anzeiger (3)
- Hereditas (2)
Universidad del País Vasco / Euskal Herriko Unibertsitatea
- • Departamento de Genética, Antropología Física y Fisiología Animal
- • Departamento de Fisiología
Leioa, Basque Country, Spain


text: Chicago's Premier Multimedia Golf Source & Authority August 2006, Vol. 10 No. 6 Titan of Turf: Stonewall Orchard Michigan's Autumnal Splendor A Day in the Life Best Buys at Crystal Woods Dave Pelz: Short Game Advisor Jeff Rude on the PGA Tour GolfChicagoMagazine.com D on't think when driving past the Golf Digest and hosting the local qualifying for the tall stalks of corn as you enter US Open in 2003 and 2005 has firmly implanted Stonewall Orchard Golf Club that Stonewall Orchard in the category of Chicago's you are the first one to draw a upper echelon public golf courses. similarity to the movie Field of Moving the Illinois PGA's Section Dreams. It's fitting, though, as this Arthur Hills' Championship from Kemper Lakes to Stonewall designed gem in northwest suburban Grayslake Orchard in 2004 further raised this course's has finally lived up to its "if you build it, they will status. This year's IPGA Section Championship come" status. is scheduled for late August at Stonewall with But it did not happen overnight, even for a University of Illinois golf coach Mike Small course that when opened in 1999 seemed to have defending his title. been there for decades. Stonewall is a product of one the best design Although it endured some lean years early firms in the world: Arthur Hills / Steve Forrest on, three consecutive "Top Course" rankings by and Associates, based in Toledo, Ohio. Their noted designs include Bighorn GC in Palm Built on over 600 acres of a previous fruit Desert, California, and Bay Harbor in Petoskey, orchard (Did you wonder about the name?) Michigan, just to name two. In 2003, Golf and wetlands, Stonewall Orchard is a graceful Chicago! ran an extended series by Hills and walk through some of the most beautiful land Forrest entitled "The Mind of the Architect." In in northern Illinois. In addition to gently rolling five easy installments these master designers hills, it is the wetlands that add to both the appeal gave us great insights into all the considerations and the danger of the course. They add a vista not involved in creating a masterpiece on turf. seen on most Illinois courses, and attract more In the first installment Hills wrote, "Our songbirds than a city person can imagine. The philosophy is to try to lay the holes gently into tall grasses in the wetlands swing and sway in the the land in the most natural and unobtrusive wind as the birds call to one another, but beware, way possible." One round at Stonewall Orchard this can be a siren song for golfers. is all the evidence players need to see that Hills Hills used the wetlands on many holes to create achieved his goal. carries either from the tee or on second shots. The Titan of Turf Stonewall Orchard by Bill Daniels Sometimes the danger is real, requiring a heroic shot, the fairways make this course one to add to your other times it is only illusory. But the psychological must-play list, if just for the fact that each hole element is the same for both, creating some anxious has a character all its own and rarely does any moments for all but the very brave. With a revised hole parallel another. slope of 148 from the back tees and a rating of 74.7, "Just like everyone else in the area, times Stonewall Orchard is not for the meek, but it's not were tough for us in the beginning, but we knew unfair in its design either: it has only 41 bunkers. we had a great course and that after a few years Playing as long as 7,074 yards from the back tees (not people would learn that we're worth checking recommended unless you make a living from there) out," said Head Pro Jeff Pajula, who has been is enough to humble even an adept player, but if you there from day one. Starting as an assistant scoot to the forward tees, there is plenty of challenge professional when the course opened, he was and danger at 6,052 yards. promoted to head pro and director of golf in 2004. No houses, lush conditions, an abundance of A solid player and teacher, Pajula finished in the wildlife, and acres of oak and pine trees lining top 12 of last year's IPGA Section Championship Stonewall Orchard is a graceful walk through some of the most beautiful land in northern Illinois. In addition to gently rolling hills, it is the wetlands that add to both the appeal and the danger of the course. to earn a spot in the PGA Club Professional side and the aforementioned wetlands fronting a Championship held earlier this summer in narrow green guarded behind with bunkers and Verona, New York. out-of-bounds. A few forced carries off the tee on "When Golf Digest first ranked us among the the front side can be a bit harrowing, especially top public courses in Chicago, we were elated, on the 8th hole, a 510-yarder that starts at a tee but we also released a collective sigh because surrounded by towering pines and a forced carry we realized that all the hard work was finally of anywhere from 160 to 250 yards over wetlans beginning to pay off," added Pajula. filled with white egret and blue heron. The front nine opens harmlessly enough with What's really fun about Stonewall are its four a 402-yard par-4 which doglegs just slightly over a terrific par-3s, starting with the 187-yard 5th hole well-placed bunker along the right hand side of the that players have to navigate between a pair of fairway and leads into a generously sized green. oak trees to a green surrounded in front and back Things get a bit more serious at hole No. 2, a 361- by water. The 182-yard 9th is another beauty, yard par-4 with a giant lake along the entire left with a lake guarding the green on the right. The elevated tee box looks down onto a spacious where two good shots are needed to put you in green protected with bunkering and framed by position to reach a green guarded in the front the clubhouse. Although Stonewall has enough by mounding and bunkers and to the side and signature-type holes to fill a full-year's calendar, behind by water. the 13th has always been a frontrunner. Playing Stonewall Orchard is the kind of course between 153 and 193 yards, this par-3 features where you need to choose the tees that fit a carry entirely over those wetlands to a green your game. While 17 handicaps and above are surrounded by pine trees with little bail out room encouraged to use the white tees, even low on either side. The final par-3, at No. 17, features handicappers will be in for a challenging day a long narrow tee box and a long narrow green. from these tees. "Our goal is to present every This combination allows the hole to play from golfer with eighteen challenging, dramatic, anywhere between 130 and 190 yards. memorable, and unique golf holes, where The finishing hole is also one that receives every golf shot must be thoroughly analyzed plenty of attention, a 612-yard behemoth par-5 continued on page 47 Stonewall Orchard Best Buys continued from page 28 continued from page 12 before it can be executed," especially when you are pitching or chipping through a tree-lined fairway. The bacon strip wrote Hills in his 2003 onto them. green is sloped severely from back to front essay for Golf Chicago!. He There are several holes that are parallel and is also fronted by water. I'm not sure how to each other, so if you are wayward, be like Linkrat and Big Nasty missed the fairway. was surely thinking about Big Nasty and miss by a bunch–kind of like You could land a small plane on this fairway. Stonewall Orchard. Michelson at Winged Foot. I mentioned vari- Seeing that from the tee gave me confidence, ety earlier; how 'bout the back nine? It offers and I pumped it 300 yards riding the prevail- equality in its par offerings. ing wind. But Linkrat had the last laugh as Stonewall Orchard Golf Club I dubbed the eighth hole the Gilligan's he curled in his downhill 18-foot slider for 25675 W. Route 60 Island hole. Unlike the Linkrat, I didn't come his lone tweedy of the round. north of I-90 to lay-up. I took a chance and Keep it straight out here at Crystal Woods Grayslake scored my first birdie of the day, capturing a and enjoy your time at a track that feels like 847-740-4890 skin from the other two wimps that played it a private club, yet will not break the pock- www.stonewallorchard.com it smart and carded a couple of pars. etbook. Don't walk—run to make your next Length: 7,074 yards Hole 12 has to be one of the best tests tee time at Crystal Woods. on this wonderful track. It plays downhill Course 8 Courtesy 8 Value 9 Rating: 74.1 Slope: 140 Head pro: Jeff Pajula Greens fee: $74 on weekends, plus $16 for cart Tee times: Accepted 14 days in advance. Bottom line: Play from the correct tees and enjoy the course layout and the beauty that surrounds you in the way of oak trees, pine trees, wildlife, water, and wetlands. Like any great course, Stonewall Orchard is not a one trick pony. It must be played numerous times in order to take advantage of the risk- Crystal Woods Hole #12. reward challenges. Short Game Advisor continued from page 41 your game, so you're ready to save strokes landing area. Think about ground condi- next time you face these situations. tions, slopes and nearby hazards, and how predict how a ball will fly, bounce, or roll If you practice these shots and learn how your ball might react once it lands. Consider from lies like the ones pictured to greens balls react to different conditions, you will train the consequence of your ball carrying too that slope away from you unless you've hit your Red Flag alerts to pop up more often and short or too far and finding trouble. Then those shots and watched their results. Too you'll be prepared to play smarter shots with play the shot that escapes the bad lie without many golfers only practice shots from level, more predictable results in tough situations. creating additional problems. "perfect" lies. During your next round, take You'll be practicing "damage control" and sav- Becoming aware of all these factors and note of how many times you hit shots from ing strokes like you see so many pros on the adapting to them to avoid major disaster an uneven or troubled lie that you haven't professional tours do week in and week out. scores will make you a better player. You'll ever practiced. I think you'll find it's time When playing recovery shots, pay atten- see the results in your handicap! you worked on this overlooked aspect of tion to more than just your lie and your Good Luck and Good Scoring to You! August 2006 47


text:
AGTech Holdings Limited
- Language: English
- 55 Pages
- Published: January 2015
Market Dynamics and a Service Assessment of the EDC and ePRO Market
The pharmaceutical industry has typically been slow to adopt new data collection technology when it comes to clinical development. And to some degree this is understandable when you are working in a highly regulated industry where patient safety is the highest priority. Why change a proven process?
However, over the past decade we have witnessed the industry's almost total acceptance of electronic data capture (EDC) technology and the growing acceptance of electronic patient reported outcomes (ePRO) applications.
Respondents provided their satisfaction with product attributes like human-machine interface, technical support, EDC page load speed, ePRO reporting portal, and integration capabilities, just to name a few. You may be surprised to find that providers that rate high on brand familiarity and use are not necessarily those that garner the highest satisfaction ratings.
Report Content:
This report contains the following four sections.
1. High-level takeaways and implications - In this section we lay out what the data in this report is telling us and how it could impact your development
Copyright and Usage Guidelines
Study Findings
High-level takeaways and implications
Sponsor and CRO organizations
EDC organizations
ePRO organizations
Electronic Data Capture (EDC)
EDC Market Dynamics
Preference for EDC vs. paper CRFs
Negative associations with EDC
EDC systems on-site
Study suitability for EDC
EDC Brand Leadership
Brand familiarity
EDC provider use
EDC provider preference
EDC Platform Performance and Satisfaction
Satisfaction with product attributes
Improving performance and features
EDC Integration with IVR & ePRO technologies
EDC Section Conclusions
Electronic Patient Reported Outcomes (ePRO)
ePRO Market Dynamics
Preference for ePRO vs. paper diaries
ePRO systems currently in use
Study suitability for ePRO
Negative associations with ePRO
ePRO Brand Leadership
ePRO Brand familiarity
ePRO service provider use
ePRO provider preference
ePRO Platform Performance and Satisfaction
Satisfaction with product attributes
Integration with IVR & EDC technologies
Improving performance and features
ePRO Section Conclusions
Trends impacting clinical development
Reducing the length of a clinical trial
Impact on Reducing Clinical Trial Time - EDC
Impact on Reducing Clinical Trial Time - ePRO
ePRO Usage: Present and Future
Trends impacting clinical development Section Conclusions
Appendix of Charts and Graphs
EDC Software
Familiarity with EDC Software
Experience Over Past 18 months
Satisfaction with Product Attributes
Human-machine Interface
Process for Dealing with Queries
Software Speed
Technical Support
Integration Capabilities
EDC Overall Satisfaction
EDC Software Application Preference
Integration with Interactive Voice Response
Integration with ePRO
EDC systems on Site
Preference for EDC or Paper
ePRO Systems
Familiarity with ePRO Devices
Familiarity with ePRO Software Applications
Experience Over the Past 18 Months
Satisfaction with Product Attributes
Human-machine Interface
Human-machine Interface Web Reporting Tool
Patient/Subjects Use of ePRO
Durability of ePRO
Logistics of Getting the Devices to Your Site
Logistic for Returning the Devices to the Vendor
Technical Support
Integration Capabilities
Overall Satisfaction with Product and Service
ePRO Application Preference
ePRO Integration With IVR
ePRO Integration With EDC
ePRO Systems on Site
Preference of ePRO Applications
Respondent Demographics
Respondent Tenure
Office/ practice Type
Clinical Trial Role
Last Conducted Trial
Personal Clinical Trial Involvement
Office/ site Clinical Trial Involvement
Familiarity with EDC products
Current Role
Therapeutic Area Responsibility
Office Location by Region
EDC Vendors:
- DataLabs
- Etrials/Merge Healthcare
- Medidata Rave
- Oracle Remote Data Capture (RDC)
- Phase Forward InForm
- Phoenix Data Systems
ePRO Vendors:
- Almac
- Arrowhead
- CRF Inc
- ICOPhone
- Invivodata
- Symfo


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Bracketology - Bubble status updates for Washington, Northwestern...
Joe LunardiJoe Lunardi provides the latest look at his S curve, looking at the new bubble statuses of teams like Washington, Northwestern and Texas.
Blog | Conversation | March 09, 2012 -
Bracketology - With all conference tournaments underway, the bid ...
Joe LunardiJoe Lunardi provides the latest look at his S curve, and it's officially moving day on the bubble with the ACC, Big Ten, MWC, SEC and WAC tournaments getting underway.
Blog | Conversation | March 08, 2012 -
The Big East bubble picture
Joe LunardiToday marks Day 2 of Big East intrigue, but the games with bracket impact won't happen until this evening. Though they aren't quite into lock territory yet, neither the Connecticut Huskies nor the West Virginia Mountaineers will fall out o...
Blog | March 07, 2012 -
Bracketology - UConn and WVU are close to safe, but other Big Eas...
Joe LunardiJoe Lunardi provides the latest look at his S Curve, and it's a big day in the Big East, with Seton Hall and South Florida both needing to advance and impress in the conference tournament in order to feel some security on Selection Sunday.
Blog | Conversation | March 07, 2012 -
Bracketology - VCU Rams could be the first bid theft after beatin...
Joe LunardiJoe Lunardi provides the latest look at his S Curve, which has Northwestern, Seton Hall, Drexel and Xavier as the current "Last Four In" teams.
Blog | Conversation | March 06, 2012 -
How UConn, Texas, Washington, others lock down NCAA tournament bi...
Joe LunardiESPN Insider and Bracketologist Joe Lunardi looks ahead and writes a checklist that bubble teams must meet if they wish to secure one of the final 13 NCAA tournament bids.
Story | Conversation | March 05, 2012 -
As of Monday, bid theft minimal
Joe LunardiFour down, 64 to go. Through Sunday afternoon we've seen the first four automatic bids for the NCAA tournament handed out and to date the bids have gone according to plan, so to speak. The Murray State Racers preempted any bubble talk by edgin...
Blog | March 04, 2012 -
Bracketology - As of Monday, bid theft minimal
Joe LunardiJoe Lunardi provides the latest look at his S Curve, which shows the Creighton Bluejays doing bubble teams a big favor by winning on Sunday.
Blog | Conversation | March 04, 2012 -
Bracketology - Wild Tuesday shifts the S-Curve
Joe LunardiJoe Lunardi provides a glimpse into the selection committee's daunting task by taking you inside a wild Tuesday night of college hoops that dramatically shifted the S-Curve.
Blog | Conversation | February 22, 2012 -
NCB - Illinois and UConn shouldn't make NCAA tournament with losi...
Joe LunardiJoe Lunardi says there could be more than three teams that make this year's NCAA tournament despite a losing conference record, and that's a problem.
Blog | Conversation | February 20, 2012 -
Bracketology - Big teams hit skids as bubble stays soft - CBB
Joe LunardiJoe Lunardi provides his midweek Seed Curve update. UConn, Alabama and West Virginia find themselves in an untimely skid, while Texas may be hitting its stride.
Blog | Conversation | February 15, 2012 -
Bracketology: UConn Huskies' bid is safe for now - CBB
Joe LunardiJoe Lunardi provides his first S-curve update of the season. See how your team is situated for the NCAA tournament as of this very moment. For UConn Huskies fans, there's no need to worry just yet.
Blog | Conversation | February 01, 2012 -
NCB - Georgetown, Arizona and other surprises and disappointments...
Joe LunardiJoe Lunardi looks at some of the most surprising (Georgetown) and disappointing (Arizona) teams of the season thus far.
Blog | Conversation | January 16, 2012 -
Bracketology - Bubble picture beginning to take shape - CBB
Joe LunardiJoe Lunardi provides an early examination of the bubble picture as the bracket begins to take shape.
Story | Conversation | December 15, 2011 -
Men's College Basketball: Virginia Tech Hokies vs. Kansas State W...
Joe LunardiYou can't get an NCAA tournament berth in November, but Joe Lunardi still found 16 games in the season's first month that will shake things up come March, including VT vs. KSU, Duke vs. Marquette and the 2K Sports Classic Championship.
Blog | Conversation | November 01, 2010 -
On second thought, USU is on the bubble
Joe LunardiEditor's note: This is updated to include all games through Saturday, March 13 My Current No. 1 Seeds Midwest: Kansas Jayhawks South: Syracuse Orange East: Kentucky Wildcats West: Duke Blue Devils Current Automatic Qualifiers (24) ...
Blog | March 14, 2010


text:
Arizona State Sun Devils
LA's storied Gibson Amphitheatre closing in Sept.
LOS ANGELES (AP) - Concert promoter Live Nation announced Wednesday that a landmark Los Angeles music venue where Bob Marley, Johnny Cash and Frank Sinatra performed will close its doors this fall.
The Gibson Amphitheatre's lease is ending in September and the venue will close its doors.
"It is a tremendous venue with a uniquely intimate setting that has made it a very special place for fans and artists alike," said Bret Gallagher, Live Nation's President of North American Concerts for Southern California and Las Vegas.
Gallagher said details will be soon announced for a series of summer farewell shows before the closure. Fans who were planning to attend concerts scheduled for after September are advised to hold on to their tickets as Live Nation makes arrangements for performances at different venues.
The 6,100-seat space opened as the Universal Amphitheatre in 1972, an outdoor venue at Universal Studios.
The mid-sized space with was loved by everyone from head bangers to heads of state for its intimate setting with superior sound. Bob Dylan, David Bowie, Madonna, Kanye West, the Grateful Dead and many other major artists performed there.
Other headliners included Presidents Barack Obama, Bill Clinton and George H.W. Bush.
And the amphitheater also hosted comedians like Jay Leno, Eddie Murphy and Louis C.K.
The closure makes way for the "Wizarding World of Harry Potter," an attraction that's part of a major theme park and studio expansion by property owner NBCUniversal.
(Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.)
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Santa Baby Set
My niece sent me this photo and asked if I could make the set for her friend,
who is expecting her baby next week. Such a cute set…how could I say "no?"
I made the newborn size, and actually used two different patterns: one for the hat and another for the diaper cover. The diaper cover pattern called for doubling the yarn; the hat pattern uses single yarn. It came out so cute! I hope to receive a photo soon from her!
* Pattern: Santa Diaper Cover * Pattern: Santa Hat * White Yarn: Red Heart Buttercup * Red Yarn: Premier Yarns * Hook: size J
I finished the "Radical Top" and before I mail it off to the anxious Birthday Girl, I had to model it… of course! I love it! I have to make myself one!!
* Pattern: "Radical Top" * Yarn: Tahki Yarns 'Tandem' (Color: Waterlilies) * Crochet Hook: H
New Project: Radical Top
After many months, I have a couple of projects in the works!
The first one is for a family member who wanted this "Radical Top" that is featured in "Crochetscene 2014." I have chosen to make it using a cotton/viscose blended yarn called, Tandem, a Tahki yarn at $9 for a 50gr ball in the color: 02 Waterlilies. I'm using a crochet hook size H to get the proper gauge of 15 Sts/4 inches. So far, it's going quick and easy!
The second project is a baby shower gift. The pattern is from the book, "Vogue Knitting Baby Gifts" and is called the Patchwork Pullover. I'm using Sinfonia Cotton and needles size 2 & 4.
I love the colors and I'm using the Intarsia method on the body of the sweater and will use the duplicate stitch for the flowers.
I couldn't wait to see what the flowers would look like, so I stopped and made up one to get a sneak-peek. Love it! This sweater will be a 3-6 month size.
So, with these two projects, I'll be a little busy for awhile.
It feels good to be busy again!
New Projects
Wow, has it been that long?! I guess it has! I have been slacking off on crocheting and knitting, but didn't know it had been this long! Well, I only have one project to show, but a lot of wonderful life memories to cherish since my last post.
This is a crocheted Giraffe that a co-worker requested for her new grandbaby. She chose the colors that matched the baby's nursery. I changed the striping pattern from the original pattern to get more of the green to show. This pattern was super easy; a beginner can handle this project with ease. It is 17 inches tall, i
ncluding the horns. If you stuff the legs and arms as you go, it is so much easier. I love this littly guy!
Crocheted Baby Sweater
I finished the Summer Sweater to match the hat and shoes and forgot to post the photos. This was a set for a friend that asked me to make her "something"…."anything!" I chose pink because her nursery was pink; she's going to be a 'girly-girl!"
The pattern is from a Japanese Crochet Book that I bought while on vacation in Seattle. The graphs in the book detail the pattern, so there is no problem with trying to translate. The changes I made were adding the flowers along the bottom edge in the front and back and not adding the teddy bear face on the back of the sweater. The pattern stitch using the two colors was intricate and I loved how it came out.
….another coffee mug cover
My girlfriend saw the purple coffee mug cover that I made a while back and asked me for a red one. These are so quick and easy to knit up and make great gifts! Again, instead of a traditional 'tea bag' I added 'mas cafe' for my Spanish speaking amiga.
…..more Baby Sneakers!
I got a request to make two more pair of crocheted baby sneakers using pink and purple. This is what I came up with, and the recipient loved them! The stitch patterns were taken from a book I found and I just substituted them for the dc rows called for. I used the same crochet thread as the red pair in the previous post. The other change I made is the shoe strings are slip stitches, instead of sc; this makes them less curly. I have been asked to make a pink and white pair next, and will post them when they are completed.


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Sorry this item is currently sold out. Please use this discount coupon for an additional 5% off during checkout:
The Outdoor Research Crave Ski Gloves are a great pair of gloves that any discerning skier be they an amateur who has only just taken up the sport to professionals who have been in love with the sport for years. They are designed to be more serious and mature with their sleek, subtle styling rather than focusing on artfulness and complexity, focusing more on designing a durable and comfortable product for an excellent value that anyone should be able to agree on.


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Three storey high building in the very bohemian "Bairro Alto". No lift, kind of kitsch decor, not very comfortable and noise from the crowds on the weekends could be a problem (there's a bar just next to the residencial that is open until 2 a.m. on Fridays and Saturdays at least) Good things about it are the location (quite central),... More
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This unit is assigned to the Keystone - Kids Ski Free Package. To receive exclusive packaged specials on lodging and lift tickets, please speak to a Destination Expert and save!
Minimum night stay requirements and other restrictions may apply. Properties displayed on this site are subject to availability at time of purchase. Valid on new reservations only. Promotion cannot be combined with any other offer.
This property is part of our EPIC VACATION PACKAGE - where you can bundle your lodging, lifts, and ground transportation for additional savings! Call our Keystone Destination Experts for details.
Play for Free when you book a 2+ night stay in this unit for travel between 12/15/14-3/15/15. Upon Check-In you will receive vouchers for Free Night Skiing on the night of arrival, Free Ice Skating Access and a 20% discount on rentals, & Free Nordic Trail Access.
Receive 25% off your 1 night or more stay for travel between 2/1/15 - 3/5/15. Promotion is blacked out 2/6/15 - 2/7/15, 2/13/15 - 2/14/15, 2/20/15 - 2/21/15 and 2/27/15 - 2/28/15.
Receive 25% off your 3 night or more stay for travel between 2/15/15 - 3/28/15. Promotion is blacked out 2/20/15 - 2/21/15.
Receive 20% off your 1 night or more stay for travel between 1/16/15 - 3/28/15. Promotion is blacked out 3/1/15 - 3/5/15.
Receive 50% off your 1 night or more stay for travel between 3/22/15 - 3/27/15.
Receive 20% off your 3 night or more stay for travel between 3/29/15 - 4/4/15.
Receive 15% off your 1 night or more stay for travel between 3/29/15 - 4/4/15.
Receive 40% off your 3 night or more stay for travel between 4/5/15 - 4/19/15.
Receive 33% off your 1 night or more stay for travel between 4/5/15 - 4/19/15.
Keystone Lodge is on the shuttle route, so guests can zip over to the ski lifts at a moment's notice. The Lodge also boasts easy access to a host of winter and summer activities, including mountain biking, championship golf, ice skating, rock climbing, whitewater rafting and more. Feel free to take a break from your adventures and luxuriate in our state-of-the-art spa with a full range of relaxing and rejuvenating spa treatments. The lodge also includes a steam room, indoor and outdoor hot tubs, an outdoor swimming pool, and even an equestrian center. Treat yourself to an exceptional dining experience at the Bighorn Steakhouse while taking in the splendid views of the Continental Divide and Keystone Lake. Or grab a quick bite at the convenient Lakeside Deli or Edgewater café before heading off on your day's activities.
This hotel suite with one king bed and living room is a two-level hotel suite with one king bedroom upstairs in the loft with television. All suites also include a downstairs sitting area with television and sofa pull-out couch and one private bathroom downstairs.
Photos are representative of the property and may differ from the actual unit that is reserved.
For more detailed information about the amenities for this property please call one of our Destination Experts at 888.538.1612
NOTE: Calendar displays standard nightly rates. Please see above for our best pricing applied to the dates you selected.
Clear Dates
Looking for more information on this property or have questions on planning your vacation? Our friendly Destination Experts are here to help. They will usually respond to your request within 5 minutes to the submission of this form.
We are excited to help you with your vacation and will contact you as quickly as possible, often within just a few minutes.
Our agents live, work and play in the destinations we offer, ensuring you benefit from local expertise while planning your trip.
They went the extra mile to offer me the most up to date rates and availability for my vacation. Their staff was very knowledgeable and quick in response to all my questions. I would book with them again!
-Shauna K.


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We stayed at this property the weekend of November 9th looking for a relaxing time away from the city. The stay was purchased through Hotwire because the Powhatan was offering a nice deal. Unfortunately, from the time we arrived the service we received as anything but 5 star. They lost our reservation from Hotwire and then gave us a small dirty room in one of the older condos. The room they provided us was not the one advertised through Hotwire, and while the actual bed itself was fine, the "living room" space had two dirty loveseats, a 13inch Zenith television, small chipped dining room table, and a kitchen that didn't have a full fridge or stove. We called the front desk immediately once we saw the room to inquire about switching, even for the $20 per night upgrade, but the front desk staff proceeded to tell us that there were no more rooms available for that night. The whole property? Hmm...the parking lot surrounding our condo section was very much empty. Besides, if you at such capacity why were you still advertising rooms on sites like groupon and Expedia that night?
But what really teed us off was that the front desk staff (Jamie, Stephanie, and Shauntey) were unfriendly and unwilling to provide any customer service. Jamie who seemed like he was the leader never stepped in to provide any customer services which reflected poorly on the property. We did not stay for the full duration of our stay because there was no way we were going to continue to deal with their attitudes.
And the icing on the cake...they pitched us for timeshare, lol. Oh yeah, and I'm still fighting to get my deposit back. Avoid, at least through these deal sites. They don't seem interested in treating those kinds of customers the same.
- Official Description (provided by the hotel):
- A Little Piece of American HistoryVirginia is one of the best places to visit if you are a history buff and want to learn more about the birth of a nation and see relics from days gone by. Williamsburg is a 170-acre historic town that has been restored to its original English condition. The Historic Powhatan Resort offers guests a little piece of colonial history with the restored Manor House (circa 1735). Nestled among 256 acres of beautiful woodland, this resort is loaded with fun things to see and do, and learn a little bit of American history. Rest, Relaxation, and a Whole Lot MoreIf you are looking for a resort that has all kinds of things to do, then you need look no further than The Historic Powhatan Resort. Here you can enjoy both indoor and outdoor swimming pools, tennis courts, an outdoor pavilion, and even a playground for the kids. Each three-bedroom suite has a fully equipped kitchen with a two-burner stovetop, a private balcony and a loft for the ultimate in relaxing vacations.If you are looking for a great meal, you can find it at The Historic Powhatan Bar & Grille, where you will find a casual family dining atmosphere for both breakfast and dinner. Open seven days a week, The Historic Powhatan Bar &Grille has an outdoor patio where you can enjoy a nice, cold drink while watching the peaceful pond (weather permitting, of course). During the breakfast buffet, enjoy being entertained by the resort's very own "first lady", Martha Washington, who will regale guests of all ages with amusing and entertaining stories.Whether you are looking for rest and relaxation, or fun and excitement, you can have it all at The Historic Powhatan Resort. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Groupon, Travelocity, Orbitz, Expedia, Despegar.com, Priceline, Hotels.com, getaroom.com, Odigeo and Tingo so you can book your The Historic Powhatan Resort reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- The Historic Powhatan Hotel Williamsburg
- Historic Powhatan Hotel
- Sunterra Powhatan Plantation
- Powhatan Plantation Williamsburg Va


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This hotel has ideal location if you want to be close to the wine cellars of Eger. That's why we came here :) The hotel is rather a small one, and the services are accordingly also moderate. The room was quite good and clean. This has a big importance! However there were some small issues: the worst thing was the... More
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- TripAdvisor is proud to partner with Booking.com, Expedia, Travelocity, Despegar.com, Priceline, Agoda, Hotels.com, TripOnline SA and Odigeo so you can book your Hotel Kodmon reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.


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FedEx Office Print & Ship Center
East Lansing, MI 48823
Get Directions Print Online Now
Hours of Operation
Monday 6:00 AM – 11:59 PM
Tuesday 6:00 AM – 11:59 PM
Wednesday 6:00 AM – 11:59 PM
Thursday 6:00 AM – 11:59 PM
Friday 6:00 AM – 11:59 PM
Saturday 8:00 AM – 9:00 PM
Sunday 9:00 AM – 9:00 PM
Latest Express Dropoff
Monday 7:45 PM
Tuesday 7:45 PM
Wednesday 7:45 PM
Thursday 7:45 PM
Friday 7:45 PM
Saturday 3:00 PM
Sunday No Pickup
Latest Ground Dropoff
Monday – Friday
No Pickup
No Pickup
FedEx Office - 626 Michigan Ave, East Lansing MI
FedEx Office is your local printing company in East Lansing, Michigan offering a wide range of printing services, including business card printing, digital color printing, and self-service copying. Come try our professional printers for yourself. Even ship with FedEx®.
Copy & Print ServicesUpload your documents online and pick them up at FedEx Office on 626 Michigan Ave or print to any of our 1800 locations.
Packing & Shipping SuppliesBuy boxes, bubble wrap, packing tape and mailing tubes or let our shipping experts help you ship with FedEx.
Computer Access & Wi-FiRent a computer with internet access or get online with free AT&T Wi-Fi access at FedEx Office in East Lansing.
Reviews for this FedEx Office Print & Ship Center
- 12/9/2014 One thing I would have liked to see was an email proof of my order. I ended up having to email in my order because of a font issue (had to… Read more
- 12/4/2014 I went to FedEx Office to print a poster. The service I received for that was very good and helpful. In checking out I received a coupon for… Read more
- 11/25/2014 The entire staff is always friendly and helpful.Janine was the team member who took my order this time and printed my newsletters quickly… Read more
- 11/23/2014 The price is a little bit high.tks. Read more
- 11/22/2014 It was my first experience with FedEx. The line was not long so I did have to wait at all. I got helped from Jennie. She explained pretty… Read more
- 11/19/2014 Janine assisted my husband and me with our purchase. She greated us from behind the counter as soon as we walked into the location. She was… Read more
- 11/9/2014 Janine helped me. I had very little experience with the printers I needed. Janine was very helpful in completing my printing needs. She was… Read more
- 11/7/2014 Quick, effective, knowledgable. Read more
- 11/6/2014 I went in to send a card to a friend in Florida. I wanted him to get it by no later than Monday. Because he will be leaving the Country… Read more
- 10/28/2014 Janene was friendly and extremely helpful. She packaged my items and assured me they would be delivered the next day by 8pm. Best help I've… Read more
- 10/27/2014 Janene really helped me out and was very accommodating. I will definitely come back!. Read more
- 10/23/2014 Janine was a great representative. She serviced me quickly, she was extremely nice and polite and answered all of my questions easily and… Read more
- 10/21/2014 Ben was helpful in every way. I came out with just what I wanted. Read more
- 10/16/2014 John W. did an excellent job helping me with my order -- discussing options, even adjusting mid-order, answering my questions & reviewing… Read more
- 9/23/2014 "Ben" has been very helpful in the various projects I have taken to this FedEx location. I am always greeted immediately when I enter the… Read more
- 9/9/2014 I'm sorry, but I don't remember the team members' names. They both were very pleasant and accommodating. My order was ready. I was checked… Read more
- 9/9/2014 She provided that extra service and was able to help us make our package more original and special for the college student that was… Read more
- 9/3/2014 He had the project done in 45 minutes, which was awesome. His willingness to get it done quickly saved me. Read more
- 9/2/2014 Janine at the East Lansing FedEx on Michigan Avenue was extremely friendly and helpful in assisting me to make my copies. She helped me a… Read more
- 8/31/2014 Janine was a great help!. Read more
FedEx Locations Nearby
FedEx Office Print & Ship Center
4950 Marsh Rd
Okemos, MI 48864
(517) 347-8656 View Details Distance: 3.91 miles Get Directions -
FedEx Ship Center
5930 Enterprise Dr
Lansing, MI 48911
(800) 463-3339 View Details Distance: 4.69 miles Get Directions -
FedEx Office Print & Ship Center
6240 W Saginaw Hwy
Lansing, MI 48917
(517) 886-2223 View Details Distance: 7.52 miles Get Directions


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Credits & Info
- Uploaded
- Jan 13, 2012 | 3:33 PM EST
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Are you ready for the fifth instalment of this blood filled shoot em up Simpsons Game? Can anyone stop Homer from this killing spree? Not if you have anything to do with it. Take control and start shooting. The targets are faster and smarter in this version. Do you have the hand eye coordination to become a Simpsons Sharp Shooter? The whole gang is back in this game, Bart, Lisa, Marge, Ned Flanders, Rod Flanders, Todd Flanders, Maud Flanders, Milhouse, Moe, Mayor Quimby, Apu and many many more! Enjoy this action packed Simpsons Game, and shoot a Flanders or two for me. If you really love The Simpsons, stand up, jump up in the air and yell Simpsonize Me!
Rated 5 / 5 stars
so many cheats...I just can't remember them...
Hahaha, you can put them in a notepad document! :)
Rated 5 / 5 stars
Ah you've done well i am adding this to favorites and i am saying yoyu are awesome thanks for these awesome games!
Ahhh, thanks man! Great review :)
Rated 4.5 / 5 stars
i loved hockey dad! this one is good as well!
Great! You'll like Flanders Killer 6 then.


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Water supply situation in Kasaragod grim in spite of summer showers
In spite of the brief spell of summer rain in north Kerala, the water supply situation in Kasaragod town is grim. Residents predominantly depend on the saline water supplied by the Kerala Water Authority (KWA).
Some of the 14 rivers in the district are already going dry. Subsequently, the district is faced with the depletion of groundwater level. Bore-wells are fast replacing conventional wells. Farmers are at the mercy of the rain to protect the standing crops.
The town relies on the KWA to meet its drinking water requirements. Various organisations and citizens' groups had protested against the supply of saline water by the KWA from a makeshift check-dam at Bavikara. The KWA cited tidal action during the month as reason for the saline infusion.
The KWA water had 1,250-mg salinity, as per studies, and various organisations had staged demonstration in front of the KWA office here accusing the government machinery of failing to complete the Rs.8.20-crore check-dam at Bavikara. The project was conceived over three decades ago.
The work got stuck midway due to technical reasons and the Minor Irrigation Department, tasked with the construction, submitted a fresh proposal to the Water Resources Department on April 25. The cost was put at Rs.11.05 crore and it was awaiting nod, KWA Executive Engineer K.R. Venugopalan told The Hindu.
If sanctioned, the department would be able to complete the work by June next, he said. The stalled work could have been completed before this monsoon had the department received timely direction from the higher authorities, he said.
A senior official of the Groundwater Department disagreed with the idea of constructing a check-dam as a solution to drinking water problems.
Long-term plans, including curbs on crusher-stone units, were required. Bore-wells should not be allowed as it allows no time for replenishment of the water table, he said. The water table was now down by over a metre, the highest ever recorded in the district, he said.
There was an urgent need to accord top priority to groundwater replenishment activities. Rainwater harvesting units should be set up on the premises of houses, government offices, parks, playgrounds, and schools, he said.
The building bylaw of the Kasargod municipality mandates the setting up of such units in all houses, he added.
Keywords: Kerala Water Authority, summer season, Kasargod municipality, groundwater table depletion, Kerala water crisis


text: I too was enticed by the beginning on the story but it quickly became mundane. Hunter was a character that I felt could have been developed into so much more. Sara was flat. Both characters were like able but neither made you want to go the extra mile. The pace of the romance was unrealistic and the backstory, felt contrived. I would give the author another shot because the premise of the book was good.


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Movie (1999)
Lowly fish-tank cleaner Rob Schneider goes to work at a gigolo's luxurious house, where his eyes are opened to a completely new way of life - but an accident with the hunk's prized pets forces him into a tricky situation. Desperate to raise a quick buck, he soon dons a G-string and starts practising his pole-dancing - and it's not long before he's busy entertaining a series of increasingly crazed women. Boisterous low-brow comedy, boasting some side-splitting references to pop culture favourites like The Matrix, co-starring William Forsythe, Eddie Griffin, Arija Bareikis, Oded Fehr and Gail O'Grady
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Ecuador's state-controlled hydrocarbons E&P company Petroproducción is focused on exploring and operating parent company Petroecuador's oil and gas deposits, as well as providing oil and gas transportation and storage services. It currently operates 44 oil fields and produces 260,000boe/d.
Petroproducción Data & Contacts
Name | Petroproducción |
Address | Av. Seis de Diciembre # 4226 y Gaspar Cañero |
City | Quito |
Fax | 593-2-2449000 |
Website | http://www.petroproduccion.com.ec/ |
Sector | Oil & Gas |
Subsector | Upstream - Exploration |
Award-winning and trusted the world over, Business News Americas is the only English and Spanish business intelligence resource for project , news , analysis and business contacts focused on and produced in Latin America. This company profile is one of thousands of companies included in the BNamericas directory of active and up-and-coming companies, including Peru LNG , Gasmig and Total Contact us today! Phone:+56 (2) 2941-0300


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Stock up on books, movies, and music! The Murphy Library Friends of the Library bookstore will be having their fall book sale. Item prices start at 25 cents and books, music CDs, VHS, and DVDs will be available for sale. Come early for the best selection!