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Atenolol, methyldopa, and chlorthalidone in moderate hypertension.
PubMed Central
Combined treatment with low doses of different drugs is widely used for moderate hypertension. The effects of atenolol and methyldopa at two dose levels and in combination at the lower doses were studied in patients with moderate hypertension on continuous treatment with moderate hypertension on continuous treatment with chlorthalidone. The mean reduction in standing blood pressures obtained with atenolol 150 and 300 mg/day was about 27/17 mm Hg and with methyldopa 750 and 1500 mg/day about 28/14 mm Hg. Combined treatment with atenolol 150 mg/day and methyldopa 750 mg/day for four weeks resulted in a reduction of 38/25 mm Hg. No difference was observed between the two doses of methyldopa. The lower dose of atenolol was better than the lower dose of methyldopa in reducing lying and standing diastolic blood pressures. These findings show that in patients on continuous treatment with chlorthalidone the addition of atenolol alone or methyldopa alone or of atenolol and methyldopa in combination is effective in the treatment of moderate hypertension. PMID:12850
Webster, J; Jeffers, T A; Galloway, D B; Petrie, J C; Barker, N P
... It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure. ... doctor may ask you to check your pulse (heart rate). Ask your pharmacist or doctor to teach you ...
Social Phobia: A Comparison of Behavior Therapy and Atenolol.
ERIC Educational Resources Information Center
Randomly assigned 72 social phobics to behavioral (flooding) or drug treatment with atenolol or placebo. Found that flooding consistently was superior to placebo, whereas atenolol was not. Flooding also was superior to atenolol on behavioral measures and composite indexes. Subjects who improved during treatment maintained gains at six-monthģ
Turner, Samuel M.; And Others
Exercise performance during captopril and atenolol treatment in hypertensive patients.
1. Maximal aerobic exercise capacity, submaximal endurance exercise performance, and exercise haemodynamics have been studied in sixteen patients with mild to moderate essential hypertension during treatment with captopril and atenolol. 2. Administration of atenolol (1 x 100 mg day-1) or captopril (1 x 100 mg day-1) for 6 weeks resulted in similar supine and erect systolic and diastolic blood pressures. Heart rate was significantly lower during atenolol treatment. 3. Exercise heart rate and systolic blood pressure were significantly lower during atenolol than during captopril treatment, exercise diastolic blood pressure (at 100W) did not differ significantly. With atenolol exercise cardiac output was significantly lower and exercise stroke volume significantly higher than with captopril. 4. Maximal work rate, maximal oxygen consumption and maximal heart rate were significantly lower during atenolol than during captopril treatment (respectively 6%, 8% and 25%). Maximal respiratory exchange ratio and lactate concentration did not differ. 5. No statistically significant difference in submaximal endurance time between atenolol and captopril was found. Endurance time was reduced by 19% during atenolol and by 13% during captopril as compared with placebo. No difference in rating of perceived exertion between atenolol and captopril was present. 6. The results indicate that atenolol will reduce blood pressure during exercise more effectively than captopril in patients with hypertension. The limitation of submaximal endurance exercise performance by both agents is of similar magnitude. This may be regarded as an unwanted side effect in certain physically active patients with hypertension. PMID:1768565
Van Baak, M A; Koene, F M; Verstappen, F T; Tan, E S
Infrared spectroscopy of racemic and enantiomeric forms of atenolol
NASA Astrophysics Data System (ADS)
The molecular structure of conformational isomorphs given by X-ray diffraction for racemic and enantiomeric atenolol were optimized at the HF/6-31G* level of theory and the infrared spectra of the structure were calculated. These spectra are used to characterize the differences between the various atenolol conformers. The spectra of the ( R, S)- and S-atenolol solid forms were recorded and the bands corresponding to the functional groups identified with the aid of the calculated spectra, fitting analysis, temperature effect and H/D isotopic exchange. Particular attention was paid to the stretch vibration modes of the functional groups present in the atenolol.
de Castro, R. A. Esteves; Canotilho, JoŃo; Barbosa, Rui M.; Redinha, J. Sim§es
Atenolol in essential hypertension during pregnancy
Microsoft Academic Search
OBJECTIVE--To determine the effect of atenolol on the outcome of pregnancy in women with essential hypertension. DESIGN--Prospective, randomised, double blind, placebo controlled study. SETTING--Hospital clinic. PATIENTS--33 Women with mild essential hypertension (systolic blood pressure 140-170 mm Hg or diastolic pressure 90-110 mm Hg on two occasions at least 24 hours apart) consecutively referred to two obstetric medical clinics. Four patients
L Butters; S Kennedy; P C Rubin
Valsartan and atenolol in patients with severe essential hypertension.
The aim of this study was to evaluate the efficacy and tolerability of valsartan, a new angiotensin II receptor antagonist, versus atenolol in the treatment of severe primary hypertension. A total of 103 adult out-patients were randomised to receive either valsartan 160 mg or atenolol 100 mg once daily for 6 weeks. If necessary, additional blood pressure (BP) control could be provided as add-on therapy. Both valsartan and atenolol decreased mean sitting diastolic BP (DBP) and mean sitting systolic BP (SBP): least squares mean change from baseline in DBP; valsartan, -20.0 mm Hg; atenolol, -20.4 mm Hg: in SBP; valsartan, -30.0 mm Hg; atenolol, -25.5 mm Hg. There was no statistically significant difference between the treatment groups. Add-on hydrochlorothiazide (HCTZ) 25 mg was required by 97.2% of patients receiving atenolol and 83.6% of patients receiving valsartan; additional verapamil SR 240 mg was also required by 58.3% of patients receiving atenolol and 64.2% receiving valsartan. Valsartan was well tolerated, with a comparable incidence of treatment-related adverse experiences in both groups. In conclusion valsartan 160 mg is as well tolerated and effective as atenolol 100 mg in lowering BP in severely hypertensive patients. PMID:9759992
Cifkova, R; Peleska, J; Hradec, J; Rosolovß, H; Pintķrovß, E; Zeman, K; Oddou-Stock, P; Thirlwell, J; Botteri, F
Renin profile, race, and antihypertensive efficacy with atenolol and labetalol.
In this randomised double-blind parallel study, we compared the efficacy of labetalol and atenolol in a group of black (n = 33) and white (n = 34) hypertensives with uncomplicated essential hypertension after obtaining pretreatment renin profiles. After single-blind placebo (14-21 days), patients with standing diastolic BP between 105-119 mmHg were randomised to receive either labetalol (100-800 mg twice daily) or atenolol (50-100 mg once daily) to achieve a DBP less than 90 mmHg. Dosage titration occurred at weekly intervals for labetalol and biweekly for atenolol. The supine BP decrease with atenolol was -18/-14 vs. -6/-6 mmHg in whites vs. blacks respectively. With labetalol, it was -13/-12 in whites and -2/-7 mmHg in blacks. Standing BPs were: -19/-14 vs. -4/-5, whites vs. blacks with atenolol and -17/-17 vs. -19/-9 mmHg with labetalol. Neither labetalol nor atenolol was as effective in black compared with white hypertensives. The atenolol but not labetalol BP response was positively correlated with pretreatment renin values. PMID:1920342
Wright, J T; DiPette, D J; Goodman, R P; Townsend, R; McKenney, J M
Sonochemical degradation of a pharmaceutical waste, atenolol, in aqueous medium.
Atenolol is a ?-blocker drug and an identified emerging pollutant. Advanced oxidation processes (AOPs) utilise the reaction of a highly oxidising species (hydroxyl radicals, (Ģ)OH) for the mineralisation of emerging pollutants since conventional treatment methodologies generally fail to degrade these compounds. In the present work, degradation of atenolol was carried out using ultrasound with frequencies ranging from 200 kHz to 1 MHz as a source of hydroxyl radical. The degradation was monitored by HPLC, total organic carbon (TOC) and chemical oxygen demand (COD) reduction and ion chromatography (IC). Nearly 90 % of degradation of atenolol was observed with ultrasound having 350 kHz. Both frequency and power of ultrasound affect the efficiency of degradation. Nearly 100 % degradation was obtained at a pH of 4. Presence of various additives such as sodium dodecyl sulphate, chloride, sulphate, nitrate, phosphate and bicarbonate was found to reduce the efficiency of degradation. Although nearly 100 % degradation of atenolol was observed under various experimental conditions, only about 62 % mineralisation (from TOC and COD measurements) was obtained. Nearly eight intermediate products were identified using high-resolution mass spectrometry (LC-Q-TOF). These products were understood as the results of hydroxyl radical addition to atenolol. The degradation studies were also carried out in river water which also showed a similar degradation profile. A mechanism of degradation and mineralisation is presented. PMID:24306722
Nejumal, K K; Manoj, P R; Aravind, Usha K; Aravindakumar, C T
Vigabarina no tratamento da epilepsia de difĒcil controle em pacientes com sĒndrome de West e esclerose tuberosa
RESUMO - Objetivo ķ relatar a eficßcia da vigabatrina no controle das convuls§es, bem como as alterań§es eletrencefalogrßficas em crianńas com esclerose tuberosa e sĒndrome de West. Mķtodo: Estudo retrospectivo, com dados clĒnicos, de neuroimagem e de eletrencefalograma. Resultados: Sete pacientes foram acompanhados e o tempo mķdio de seguimento foi 10 anos. Dos pacientes, quatro eram do sexo feminino e
Newra Tellechea Rotta; Alexandre Rodrigues da Silva; Lygia Ohlweiler; Rudimar Riesgo
This study was designed to assess pharmacokinetic parameters and pattern of pha rmacodynamic effects (heart rate and blood pressure) of 100 mg Atenolol tablets in comparison with those of 100 mg Tenormin tablets as reference. A double blind cross over study was carried out among 12 healthy male subjects. A HPLC system using RP -C18 column and fluorescence detector was
Effects of orange juice on the pharmacokinetics of atenolol
Objective: Fruit juices can significantly change the pharmacokinetics of several drugs. Our objective was to investigate the effect of orange juice on the pharmacokinetics of the beta-blocking agent atenolol. Methods: In a randomized cross-over study with two phases and a washout of 2 weeks, ten healthy volunteers took either 200 ml orange juice or water thrice daily for 3 days
J. J. Lilja; K. Raaska; P. J. Neuvonen
Formulation and Evaluation of Buccal Patches for Delivery of Atenolol
Buccal patches for the delivery of atenolol using sodium alginate with various hydrophilic polymers like carbopol 934 P, sodium\\u000a carboxymethyl cellulose, and hydroxypropyl methylcellulose in various proportions and combinations were fabricated by solvent\\u000a casting technique. Various physicomechanical parameters like weight variation, thickness, folding endurance, drug content,\\u000a moisture content, moisture absorption, and various ex vivo mucoadhesion parameters like mucoadhesive strength, force
Surya N. Ratha Adhikari; Bhabani S. Nayak; Amit K. Nayak; Biswaranjan Mohanty
Mucous membrane pemphigoid in a patient with hypertension treated with atenolol: a case report
Introduction Atenolol is commonly used by patients with hypertension, angina pectoris, or myocardial infarction. There have been reports of various adverse effects associated with the use of atenolol including bullous pemphigoid. To the best of our knowledge we present the first case report of atenolol-induced mucous membrane pemphigoid. Case presentation A 42-year-old Thai man presented to our faculty after developing generalized fiery red gingiva and ulcerations on the buccal and labial mucosa after beginning atenolol treatment. Drug-induced mucous membrane pemphigoid was diagnosed from his clinical presentation and histopathologic and direct immunofluorescence examinations, combined with a history of beginning, and withdrawal, from atenolol therapy, with the lesions resolving after the cessation of atenolol therapy. Conclusions To the best of our knowledge this is the first case of atenolol-induced oral mucous membrane pemphigoid reported in the literature. The observed lesions responded to withdrawal of the offending drug with complete remission. While drug-induced mucous membrane pemphigoid is an uncommon condition, dentists or other health care workers should include this condition in the differential diagnosis when a patient uses drugs suspected to be involved with drug-induced pemphigoid. PMID:23110919
Comparison between moexipril and atenolol in obese postmenopausal women with hypertension.
The present study investigated the effect of the new ACE-inhibitor moexipril versus the beta 1-adrenergic blocker atenolol on metabolic parameters, adverse events (AEs) and sitting systolic (SSBP) and sitting diastolic blood pressure (SDBP) in obese postmenopausal women with hypertension (stage I and II). After a 4-week placebo run-in phase, 116 obese, postmenopausal women with primary hypertension were randomised into two treatment groups receiving once daily dosages of either moexipril 7.5 mg or atenolol 25 mg initially (mean age: 57 +/- 7 years in both groups; mean weight: 94 kg in the moexipril group and 89 kg in the atenolol group, corresponding to a body mass index (BMI) of 35.2 kg/m2 and 34.1 kg/m2 in both groups, respectively). After 4 and 8 weeks, the dosages were uptitrated to moexipril 15 mg, or if necessary to moexipril 15 mg/hydrochlorothiazide (HCTZ) 25 mg, or to atenolol 50 mg and atenolol 50 mg/HCTZ 25 mg, in patients whose blood pressure was not sufficiently controlled. At endpoint, metabolic parameters (total cholesterol, triglycerides, LDL, HDL, glucose, insulin) were not significantly altered in either treatment group. Most frequent adverse events under monotherapy (moexipril/atenolol) were asthenia (5.3/13.0%), headache (13.2/21.7%), cough (7.9/6.5%), pharyngitis (21.1/8.7%) and peripheral oedema (5.3/13.0%). Overall at least one AE was reported in 66% of the patients treated with moexipril and in 78% of those treated with atenolol. Reduction of SSBP/SDBP at endpoint was 14.7 +/- 1.9/10.0 +/- 1.1 and 8.7 +/- 1.9/8.4 +/- 1.1 mmHg after treatment with moexipril and atenolol, respectively. The results showed that moexipril and atenolol are equally effective in reducing blood pressure without adversely affecting blood lipids and carbohydrate metabolism. PMID:9819786
Stimpel, M; Koch, B; Weber, M A
The effects of atenolol (tenormin) and methyldopa on simple tests of central nervous function.
Two identical studies, one comparing the effect of single doses of a new beta-adrenoceptor blocker, atenolol (Tenormin) (50 mg and 100 mg) and placebo, and the other comparing the effect of single doses of methyldopa (250 mg and 500 mg) and placebo, in healthy volunteers, were carried out. 2 In both studies the effect of the drugs upon reaction time, critical flicker frequency, subjective drowsiness, pulse rate and blood pressure was measured. 3 Atenolol produced no effect upon reaction time, critical flicker frequency or subjective feelings, while methyldopa produced a statistically significant prolongation of reaction time and a statistically significant increase in the subjective sensation of drowsiness. 4 Atenolol produced statistically significant reductions in systolic and diastolic blood pressure and in pulse rate while methyldopa was without effect. 5 It is concluded that atenolol is unlikely to produce the side effects of sedation or drowsiness. PMID:9954
Bayliss, P F; Duncan, S M
EPA Science Inventory
Atenolol is a cardioselective B-adrenoreceptor blocking agent, used for treatment of hypertension, including hypertension in pregnancy. Beta-adrenoreceptor antagonists have been impacted in the production of intrauterine growth retardation and considerable range of neonatal probl...
Atenolol versus amlodipine versus isosorbide-5-mononitrate on anginal symptoms in syndrome X.
The effects of a beta blocker (atenolol), a calcium antagonist (amlodipine), and a nitrate (isosorbide-5-mononitrate) on anginal symptoms in 10 patients with syndrome X were assessed in a crossover, double-blind, randomized trial. Only atenolol was found to significantly improve chest pain episodes, suggesting that it should be the preferred drug when starting pharmacologic treatment of patients with syndrome X. PMID:10513787
Lanza, G A; Colonna, G; Pasceri, V; Maseri, A
Beneficial Effects of Nebivolol in Comparison with Atenolol on Safety and Tolerability in Essential Hypertension
Introduction: Hypertension, ōThe silent killerö is a multifactorial disorder which is asymptomatic and if left untreated leads to lethal complications. Nebivolol is a third generation beta blocker with additional vasodilating property due to nitric oxide release. Aim: The current study aims to assess efficacy and safety of Nebivolol and compare with Atenolol. Methods: This was prospective, double blind, comparative controlled clinical study. Total 90 patients were enrolled into study as per selection criteria. Patients were randomized to receive Atenolol and Nebivolol with 45 patients in each group for 12 weeks. Results and Conclusion: The mean reduction diastolic blood pressure in Nebivolol and Atenolol group was 10.77▒2.60 and 10.05▒2.83 respectively. The number of patients with adverse effect events was higher in the Atenolol than in the Nebivolol group (36.84% of Atenolol Vs 12.82% of Nebivolol). Thus it can be concluded that, for the same antihypertensive effect, Nebivolol was better tolerated than Atenolol. PMID:25120998
Inamdar, S.C.; V.B., Karande; S.R., Burute; M.B., Murthy; A., Ghatak
AvaliańŃo clĒnica, endosc¾pica e manomķtrica da deglutińŃo em pacientes com miastenia grave autoimune adquirida
RESUMO - Apresentamos 22 pacientes com diagn¾stico de miastenia grave autoimune adquirida (MGAA), com queixa de disfagia orofarĒngea, avaliados pela anßlise fonoaudiol¾gica, nasofibrolaringosc¾pica e manomķtrica de esfĒncter esofßgico superior, com o objetivo de avaliar as fases do processo de deglutińŃo e os aspectos anat¶micos e funcionais do sistema estomatognßtico. A idade dos pacientes variou de 19 a 74 anos; 19
Adriana Leico Oda; Ana L·cia de MagalhŃes Leal Chiappetta; Marcelo Annes; Irene Queiroz Marchesan; Acary Souza Bulle Oliveira
The sub-lethal effects and tissue concentration of the human pharmaceutical atenolol in rainbow trout (Oncorhynchus mykiss).
Atenolol is a highly prescribed anti-hypertensive pharmaceutical and a member of the group of ?-blockers. It has been detected at concentrations ranging from ngL(-1) to low ?gL(-1) in waste and surface waters. The present study aimed to assess the sub-lethal effects of atenolol on rainbow trout (Oncorhynchus mykiss) and to determine its tissue-specific bioconcentration. Juvenile rainbow trout were exposed for 21 and 42days to three concentration levels of atenolol (1?gL(-1) - environmentally relevant concentration, 10?gL(-1), and 1000?gL(-1)). The fish exposed to 1?gL(-1) atenolol exhibited a higher lactate content in the blood plasma and a reduced haemoglobin content compared with the control. The results show that exposure to atenolol at concentrations greater than or equal to 10?gL(-1) significantly reduces both the haematocrit value and the glucose concentration in the blood plasma. The activities of the studied antioxidant enzymes (catalase and superoxide dismutase) were not significantly affected by atenolol exposure, and only the highest tested concentration of atenolol significantly reduced the activity of glutathione reductase. The activities of selected CYP450 enzymes were not affected by atenolol exposure. The histological changes indicate that atenolol has an effect on the vascular system, as evidenced by the observed liver congestion and changes in the pericardium and myocardium. Atenolol was found to have a very low bioconcentration factor (the highest value found was 0.27). The bioconcentration levels followed the order liver>kidney>muscle. The concentration of atenolol in the blood plasma was below the limit of quantification (2.0ngg(-1)). The bioconcentration factors and the activities of selected CYP450 enzymes suggest that atenolol is not metabolised in the liver and may be excreted unchanged. PMID:25129157
Steinbach, Christoph; Burkina, Viktoriia; Fedorova, Ganna; Grabicova, Katerina; Stara, Alzbeta; Velisek, Josef; Zlabek, Vladimir; Schmidt-Posthaus, Heike; Grabic, Roman; Kocour Kroupova, Hana
AvaliańŃo da expressŃo gĻnica relacionada Ó receptividade endometrial em pacientes submetidos Ó embolizańŃo do mioma uterino.
E-print Network
??OBJETIVO: Avaliar a receptividade endometrial de pacientes submetidas Ó embolizańŃo do mioma uterino, analisando a expressŃo gĻnica de LIF, IL-11, IL-6, claudina-4, HoxA-10, HoxA-11, receptorģ (more)
Sandro Garcia Hilßrio
An assessment of lacidipine and atenolol in mild to moderate hypertension.
1. The aim of this randomised, double-blind four way crossover study was to assess the interaction between the new calcium antagonist, lacidipine and atenolol, in patients with mild to moderate hypertension. 2. Sitting blood pressure at 4 h post-dosing with lacidipine (4 mg) and atenolol (100 mg) alone was significantly lower compared with placebo (137/89 +/- 3/3 mmHg; 142/89 +/- 5/3 mmHg; and 154/98 +/- 5/3 mmHg respectively; P < 0.001). Co-administration of both drugs produced a significant additive effect compared with atenolol and lacidipine alone (124/80 +/- 4/2 mmHg; P < 0.002). 3. Heart rate on treatment with lacidipine alone was significantly greater at 4 h compared with placebo (86 +/- 1 beats min-1 and 74 +/- 2 beats min-1 respectively; P < 0.001). When both drugs were used in combination, there was a significant decrease in pulse rate compared with lacidipine alone (58 +/- 1 beats min-1 and 86 +/- 1 beats min-1 respectively; P < 0.001). 4. Home blood pressure recordings confirmed the statistically significant reduction in blood pressure on co-dosing (120/82 +/- 10/2 mmHg) compared with lacidipine (140/92 +/- 5/3 mmHg) and atenolol (146/90 +/- 6/3 mmHg) given alone (P < 0.05). 5. Lacidipine alone produced a significant exercise tachycardia compared with atenolol alone and the atenolol/lacidipine combination (97 +/- 8 beats min-1; 65 +/- 4 beats min-1 and 75 +/- 7 beats min-1 respectively; P < 0.001). Exercise tolerance was not adversely affected by the co-administration of both lacidipine and atenolol. PMID:8148217
Lyons, D; Fowler, G; Webster, J; Hall, S T; Petrie, J C
Stereoselective uptake of atenolol into storage granules isolated from PC12 cells.
Atenolol has been shown to be stored and secreted from PC12 cells by calcium-dependent and stereoselective mechanisms. The present study was designed to determine if the cytoplasmic amine storage granule was the site for storage and release of atenolol and if the drug was, in fact, an enantiomeric selective substrate for the vesicular amine transport protein. Uptake of racemic [3H]atenolol and (-)-[3H]norepinephrine was studied in a vesicular preparation of storage granules isolated from PC12 cells. Uptake of both molecules was found to be ATP-dependent (80%) and to reach steady state in approximately 10 to 15 min. Uptake and storage was inhibited (95%) by either reserpine, an inhibitor of the vesicular amine carrier, or by nigericin which dissipates the proton gradient across the membrane. Uptake of neither compound was inhibited by desipramine, an inhibitor of uptake 1, or oligomycin, an inhibitor of mitochondrial adenosine triphosphatase. Furthermore, uptake of the (-)-enantiomer of atenolol was found to be approximately 5-fold greater than the (+)-enantiomer. Kinetic studies revealed a Km of 184 microM for (+/-)-atenolol and 79 microM for (-)-norepinephrine and Vmax values of 750 and 503 pmol/min/mg of protein for atenolol and norepinephrine, respectively. The interaction of the two compounds with the transport process was found to be kinetically competitive. In separate experiments, atenolol was also found to be transported stereoselectively into bovine adrenal chromaffin granule ghosts and to be ATP dependent (85%) and reserpine sensitive (44%).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2724136
Bagwell, E E; Webb, J G; Walle, T; Gaffney, T E
Cadralazine and chlorthalidone as a second-step drug with atenolol in hypertensive patients: Differences in blood pressure control during exercise
The long-term efficacy of a new vasodilator, cadralazine (ISF 2469), and chlorthalidone have been compared in 20 hypertensive patients not adequately controlled by atenolol. After 4 weeks of treatment with atenolol 100 mg once daily, patients whose diastolic blood pressure was >95 mmHg were randomly divided into two groups to receive in addition to atenolol, either cadralazine 15 mg once
F. V. Costa; C. Borghi; A. Mussi; E. Ambrosioni
Simultaneous Determination of Losartan Potassium, Atenolol and Hydrochlorothiazide in Pharmaceutical Preparations by Stability-Indicating UPLC
A stability-indicating UPLC method was developed for the simultaneous quantitative determination of losartan potassium, atenolol,\\u000a and hydrochlorothiazide in pharmaceutical dosage forms in the presence of degradation products. The separation was achieved\\u000a on a simple isocratic method (water: acetonitrile: triethyl amine: ortho phosphoric acid (60:40:0.1:0.1, v\\/v) at 0.7ĀmLĀmin?1, a detection wavelength of 225Ānm). The retention times of losartan potassium, atenolol, and
D. Durga Rao; N. V. Satyanarayana; S. S. Sait; Y. Ramakoti Reddy; K. Mukkanti
Pharmacokinetics of atenolol enantiomers in humans and rats.
Single dose pharmacokinetics of atenolol (AT) enantiomers was studied in human volunteers and in rats. After oral administration of 50 mg of racemic AT to humans, the areas under the plasma concentration-time curves (AUCs; mean +/- SD) were 1640 +/- 602 and 1860 +/- 652 (ng/mL)h for the S(-)- and R(+)-enantiomers, respectively (p less than 0.05). The small difference in the AUC was a reflection of a slight, but statistically significant (p less than 0.05) difference in the renal clearance (CLr, mL/min) of the enantiomers [129 +/- 32, S(-)-AT; 120 +/- 29, R(+)-AT]. However, the two enantiomers were not different from each other (p greater than 0.05) with respect to the volume of distribution (V lambda, L/kg) [0.879 +/- 0.342, S(-)-AT; 0.790 +/- 0.255, R(+)-AT] or the terminal elimination rate constant (lambda z, h-1) [0.113 +/- 0.038, S(-)-AT; 0.114 +/- 0.036, R(+)-AT]. After iv administration of 10 mg/kg of the racemic AT to rats, the R(+)-enantiomer achieved higher AUC values [(ng/mL)h] compared with its antipode (p less than 0.05) [3630 +/- 1040, S(-)-AT; 4020 +/- 1080, R(+)-AT]. Similar to the human results, this difference was due to a stereoselective renal clearance (mL/min/kg) in favor of S(-)-AT [14.9 +/- 5.78, S(-)-AT; 13.0 +/- 4.88, R(+)-AT; p less than 0.05].(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2280355
Mehvar, R; Gross, M E; Kreamer, R N
Design, Synthesis, and In Vitro Kinetics Study of Atenolol Prodrugs for the Use in Aqueous Formulations
Based on DFT, MP2, and the density functional from Truhlar group (hybrid GGA: MPW1k) calculations for an acid-catalyzed hydrolysis of nine Kirby's N-alkylmaleamic acids and two atenolol prodrugs were designed. The calculations demonstrated that the amide bond cleavage is due to intramolecular nucleophilic catalysis by the adjacent carboxylic acid group and the rate-limiting step is determined based on the nature of the amine leaving group. In addition, a linear correlation of the calculated and experimental rate values has drawn credible basis for designing atenolol prodrugs that are bitterless, are stable in neutral aqueous solutions, and have the potential to release the parent drug in a sustained release manner. For example, based on the calculated B3LYP/6-31 G (d,p) rates, the predicted t1/2 (a time needed for 50% of the prodrug to be converted into drug) values for atenolol prodrugs ProD 1-ProD 2 at pH 2 were 65.3 hours (6.3 hours as calculated by GGA: MPW1K) and 11.8 minutes, respectively. In vitro kinetic study of atenolol prodrug ProD 1 demonstrated that the t1/2 was largely affected by the pH of the medium. The determined t1/2 values in 1N HCl, buffer pH 2, and buffer pH 5 were 2.53, 3.82, and 133 hours, respectively. PMID:24526887
Qtait, Alaa; Dajani, Khulod Khayyat; Abu Lafi, Saleh
Anxiolytic effects of acebutolol and atenolol in healthy volunteers with induced anxiety
Acebutolol (400 mg once daily), atenolol (100 mg once daily) and placebo were self administered to 12 healthy male volunteers in a double-blind crossover study. Each drug treatment was administered for 4 days so that subjects' plasma levels of the drug were at steady state. Subjects were tested on the 4th day. On each of the 3 test days subjects
S. G. Kilmittster; M. J. Lewis; D. M. Jones
Design, synthesis, and in vitro kinetics study of atenolol prodrugs for the use in aqueous formulations.
Based on DFT, MP2, and the density functional from Truhlar group (hybrid GGA: MPW1k) calculations for an acid-catalyzed hydrolysis of nine Kirby's N-alkylmaleamic acids and two atenolol prodrugs were designed. The calculations demonstrated that the amide bond cleavage is due to intramolecular nucleophilic catalysis by the adjacent carboxylic acid group and the rate-limiting step is determined based on the nature of the amine leaving group. In addition, a linear correlation of the calculated and experimental rate values has drawn credible basis for designing atenolol prodrugs that are bitterless, are stable in neutral aqueous solutions, and have the potential to release the parent drug in a sustained release manner. For example, based on the calculated B3LYP/6-31 G (d,p) rates, the predicted t1/2 (a time needed for 50% of the prodrug to be converted into drug) values for atenolol prodrugs ProD 1-ProD 2 at pH 2 were 65.3 hours (6.3 hours as calculated by GGA: MPW1K) and 11.8 minutes, respectively. In vitro kinetic study of atenolol prodrug ProD 1 demonstrated that the t1/2 was largely affected by the pH of the medium. The determined t1/2 values in 1N HCl, buffer pH2, and buffer pH 5 were 2.53, 3.82, and 133 hours, respectively. PMID:24526887
Karaman, Rafik; Qtait, Alaa; Dajani, Khulod Khayyat; Abu Lafi, Saleh
Atenolol and amlodipine combination overdose managed with continuous venovenous hemodiafiltration: A case report.
We present a patient of who ingested large dose of of atenolol and amlodipine and was treated successfully with continuous venovenous hemodiafiltration. Early recognition of indications for renal support and early initiation of the same is the key to successful management. PMID:25249727
Sandeep, P; Ram, R; Sowgandhi, N; Reddy, S A; Katyarmal, D T; Kumar, B S; Kumar, V S
Atenolol is a beta-adrenoreceptor blocker used for treatment of hypertension in pregnancy. This study evaluates the reporting frequency of adverse pre- and postnatal outcomes in a series of 70 cases of maternal exposure during gestation, derived from 140 reports to FDA with Ateno...
Atenolol Induced HDL-C Change in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study
We sought to identify novel pharmacogenomic markers for HDL-C response to atenolol in participants with mild to moderate hypertension. We genotyped 768 hypertensive participants from the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study on the Illumina HumanCVD Beadchip. During PEAR, participants were randomized to receive atenolol or hydrochlorothiazide. Blood pressure and cholesterol levels were evaluated at baseline and after treatment. This study focused on participants treated with atenolol monotherapy. Association with atenolol induced HDL-C change was evaluated in 232 whites and 152 African Americans using linear regression. No SNPs achieved a Bonferroni corrected P-value. However, we identified 13 regions with consistent association across whites and African Americans. The most interesting of these regions were seven with prior associations with HDL-C, other metabolic traits, or functional implications in the lipid pathway: GALNT2, FTO, ABCB1, LRP5, STARD3NL, ESR1, and LIPC. Examples are rs2144300 in GALNT2 in whites (P=2.29x10-4, ?=-1.85 mg/dL) and rs12595985 in FTO in African Americans (P=2.90x10-4, ?=4.52 mg/dL), both with consistent regional association (P<0.05) in the other race group. Additionally, baseline GALNT2 expression differed by rs2144300 genotype in whites (P=0.0279). In conclusion, we identified multiple gene regions associated with atenolol induced HDL-C change that were consistent across race groups, several with functional implications or prior associations with HDL-C. PMID:24116192
McDonough, Caitrin W.; Gillis, Nancy K.; Alsultan, Abdullah; Chang, Shin-Wen; Kawaguchi-Suzuki, Marina; Lang, Jason E.; Shahin, Mohamed Hossam A.; Buford, Thomas W.; El Rouby, Nihal M.; Sa, Ana C.C.; Langaee, Taimour Y.; Gums, John G.; Chapman, Arlene B.; Cooper-DeHoff, Rhonda M.; Turner, Stephen T.; Gong, Yan; Johnson, Julie A.
Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation
Aim: To develop a simple, accurate, rapid and precise UV spectrophotometric method for the estimation of atenolol in combination with losartan potassium and hydrochlorothiazide. Materials and Methods: The method employs formation and solving simultaneous equation using 251.60 nm and 224.20 nm for losartan potassium and atenolol, 224.20 and 271.60 for atenolol and hydrochlorothiazide as two analytical wavelengths, using methanol water as a solvent. Results and Conclusion: The linearity was observed in the concentration range of 5-30 Ąg/ml (r=0.9991) for losratan pottassium, 2 - 12 Ąg/ml (r = 0.9995) for atenolol and 2 - 14 Ąg/ml (r = 0.9993) for hydrochlorothiazide. The results of the method were validated statistically and by recovery studies. PMID:21180476
Bari, Sanjay; Sathe, Shital; Jain, Pritam; Surana, Sanjay
Effect of antihypertensive treatment with valsartan or atenolol on sexual activity and plasma testosterone in hypertensive men
Objective. To compare the effects of valsartan and atenolol on sexual activity and plasma testosterone in newly diagnosed, previously untreated, essential hypertensive male subjects. Methods. One hundred and ten hypertensive men, aged 40-49 years, homogeneous for marital status and without any previous sexual dysfunction were randomly treated with valsartan 80 mg daily (o.d.) or atenolol 50 mg o.d. for 16
Roberto Fogari; Paola Preti; Giuseppe Derosa; Gianluigi Marasi; Annalisa Zoppi; Andrea Rinaldi; Amedeo Mugellini
Effects of therapy with nifedipine GITS or atenolol on mental stress-induced ischemic left ventricular dysfunction
Objectives. We sought to determine the effect of nifedipine gastrointestinal therapeutic system (GITS) or atenolol on ischemic left ventricular dysfunction induced by mental stress.Background. The efficacy of conventional antianginal therapy in preventing myocardial ischemia induced by mental stress is unknown.Methods. Nifedipine GITS, atenolol and placebo were administered to 15 subjects with stable angina in a double-blind crossover trial. Subjects underwent
Thomas C. Andrews; John D. Parker; Sue Jacobs; Richard Friedman; Nancy Cummings; Gail MacCallum; Finn Mannting; Geoffrey H. Tofler; William Carlson; James E. Muller; Peter H. Stone
Simultaneous determination of atenolol and amlodipine in tablets by high-performance thin-layer chromatography
A new simple, precise, rapid and selective high-performance thin-layer chromatographic (HPTLC) method has been developed for the simultaneous determination of atenolol (ATL) and amlodipine (AMLO) in tablets, using methylene chloride:methanol:ammonia solution (25% NH3) (8.8:1.3:0.1; v\\/v) as the mobile phase and Merck HPTLC plates (0.2 mm thickness) precoated with 60F254 silica gel on aluminium sheet as the stationary phase. Detection was
A. P. Argekar; S. G. Powar
Relative activities of atenolol and metoprolol on the cardiovascular system of man
SummaryĀĀThe effects or oral atenolol (100 mg once\\/day) and metoprolol (100 mg once\\/day, 100 mg twice\\/day and 300 mg once\\/day) have\\u000a been compared with placebo on the heart rate and systolic blood pressure responses to exercise in 5 healthy volunteers. The\\u000a drugs were given for 5 days in a double blind randomised fashion with each volunteer receiving each dose of
J. D. Harry; J. M. Cruickshank; J. Young; N. Barker
Withdrawal phenomena after atenolol and bopindolol: hormonal changes in normal volunteers.
1. In order to observe and compare the withdrawal phenomena which follow treatment with the beta-adrenoceptor blocking drugs, bopindolol (with partial agonist activity PAA) and atenolol (without PAA), two groups of six normal volunteers were studied before, during and after 16 days drug administration. 2. Measurements of plasma levels of cortisol, prolactin, insulin, noradrenaline, adrenaline, glucose and potassium were made during a pre-treatment baseline period, on maximum dose and for 21 days after drug withdrawal. Isoprenaline infusions were given to determine sensitivity of heart rate responses and haemodynamic changes measured in response to physiological manoeuvres. 3. Following atenolol withdrawal the results show hormonal evidence of adrenergic overactivity in the form of elevation of plasma cortisol, insulin and glucose levels. After bopindolol withdrawal there was, in contrast, an overshoot of plasma prolactin and a persistent elevation of plasma potassium and adrenaline post-isoprenaline. 4. The hormonal changes which follow withdrawal of atenolol and bopindolol are associated with haemodynamic changes reported elsewhere (Walden et al., 1990). 5. These observations provide confirmatory evidence of a post beta-adrenoceptor blockade withdrawal syndrome which differs between the two drugs studied and this may reflect the properties of the drugs, in particular the PAA of bopindolol. PMID:1981317
Walden, R J; Tomlinson, B; Graham, B; Smith, C; Betteridge, D J; Prichard, B N
Formulation and optimization of mucoadhesive bilayer buccal tablets of atenolol using simplex design method
Introduction: In the present study, mucoadhesive buccal bilayer tablets of atenolol were fabricated with the objective of avoiding first pass metabolism and to improve its bioavailability with reduction in dosing frequency. Hence, the aim of this work was to design oral controlled release mucoadhesive tablets of atenolol and to optimize the drug release profile and bioadhesion. Materials and Methods: Bilayer buccal tablets of atenolol were prepared by direct compression method using simplex method of optimization to investigate the combined effect of hydroxypropyl methylcellulose 15 cps (X1), Carbopol (X2) and mannitol (X3); the in vitro drug release (Y1) and mucoadhesive strength (Y2) were taken as responses. The designed tablets were evaluated for various physical and biological parameters like drug content uniformity, in vitro drug release, short-term stability, and drug- excipient interactions (FTIR). Results: The formulation C containing hydroxypropyl methylcellulose 15 cps (10% w/w of matrix layer), Carbopol 934p (10% w/w of matrix layer) and mannitol (channeling agent, 40% w/w of matrix layer) was found to be promising. This formulation exhibited an in vitro drug release of 89.43% in 9 h along with satisfactory bioadhesion strength (7.20 g). Short-term stability studies on the promising formulation indicated that there are no significant changes in drug content and in vitro dissolution characteristics (P<0.05). IR spectroscopic studies indicated that there are no drug-excipient interactions. PMID:23071958
Shirsand, SB; Suresh, Sarasija; Keshavshetti, GG; Swamy, PV; Reddy, P Vijay Prakash
In-vitro Relationship between Proteinbinding and Free Drug Concentrations of a Water-soluble Selective Beta-adrenoreceptor Antagonist (Atenolol) and Its Interaction with Arsenic
The degree of binding of a drug to plasma proteins has a marked effect on its distribution, elimination, and pharmacological effect since only the unbound fraction is available for distribution into extra-vascular space. The protein-binding of atenolol was measured by equilibrium dialysis in the bovine serum albumin (BSA). Free atenolol concentration was increased due to addition of arsenic which reduced
M. A. Alam; M. A. Awal; N. Subhan; M. Mostofa
Study of polymorphism of Atenolol and Captopril antihypertensives using x-ray powder diffraction and Rietveld refinement
Characterization of bulk drugs has become increasingly important in the pharmaceutical industry. X-ray powder diffractometry is an effective technique for the identification of crystalline solid-phase drugs. The technique is unique, since it combines specificity with a high degree of accuracy for the characterization of pharmaceuticals in solid state and is an especially useful method to describe the possible polymorphic behavior of drugs substances. In this work X-ray diffraction data have been obtained for two well-known antihypertensive drugs currently being administered in tablet form. They include atenolol and captopril. Atenolol and captopril were purchased from drugstore. The characterizations of the atenolol and captopril samples were carried out by FTIR spectroscopy and X-ray powder diffraction (XRPD).
Sato, Juliana; Ferreira, Fabio
Gas chromatographic-mass spectrometric differentiation of atenolol, metoprolol, propranolol, and an interfering metabolite product of metoprolol.
Over a 10-year period, 1993-2002, Federal Aviation Administration identified 50 pilot fatalities involving atenolol, metoprolol, and propranolol, which is consistent with the fact that these drugs have been in the lists of the top 200 drugs prescribed in the U.S. In a few of the 50 pilot fatality cases, initial analysis suggested the presence of atenolol and metoprolol. However, there was no medical history with these cases supporting the use of both drugs. Therefore, atenolol, metoprolol, and/or propranolol, with their possible metabolite(s), were re-extracted from the selected case specimens, derivatized with pentafluoropropionic anhydride (PFPA), and analyzed by gas chromatography-mass spectrometry (GC-MS). The MS spectra of these three antihypertensives and a metoprolol metabolite are nearly identical. All of the PFPA derivatives had baseline GC separation, with the exception of a metoprolol metabolite product, which co-eluted with atenolol. There were four primary mass fragments (m/z 408, 366, 202, and 176) found with all of the PFPA-beta-blockers and with the interfering metabolite product. However, atenolol has three unique fragments (m/z 244, 172, and 132), metoprolol has two unique fragments (m/z 559 and 107), propranolol has four unique fragments (m/z 551, 183, 144, and 127), and the metoprolol metabolite product has two unique fragments (m/z 557 and 149). These distinctive fragments were further validated by using a computer program that predicts logical mass fragments and performing GC-MS of deuterated PFPA-atenolol and PFPA-propranolol and of the PFPA-alpha-hydroxy metabolite of metoprolol. By using the unique mass fragments, none of the pilot fatality cases were found to contain more than one beta-blocker. Therefore, these mass ions can be used for differentiating and simultaneously analyzing these structurally similar beta-blockers in biological samples. PMID:16168172
Angier, Mike K; Lewis, Russell J; Chaturvedi, Arvind K; Canfield, Dennis V
An open label, randomised, crossover study comparing sotalol and atenolol in the treatment of symptomatic paroxysmal atrial fibrillation
OBJECTIVEŚTo compare sotalol and atenolol in the treatment of symptomatic paroxysmal atrial fibrillation.?DESIGNŚProspective, randomised, open label, crossover study.?SETTINGŚUniversity hospital.?PATIENTSŚ47 subjects aged over 50Āyears were recruited from the hospital outpatient department following ECG documentation of paroxysmal atrial fibrillation that coincided with symptoms. Six patients withdrew and 41Ācompleted the trial.?INTERVENTIONSŚPatients were randomised to one month's treatment with sotalol 80Āmg twice daily or atenolol 50Āmg once daily. Treatment arms were then crossed over. Patients underwent 72Āhour Holter monitoring before randomisation and repeat studies were carried out at the end of both treatment periods. Symptom assessments were completed using linear analogue scales and the Nottingham health profile.?MAIN OUTCOME MEASUREŚFrequency of paroxysmal atrial fibrillation; secondary outcome measures included average and total duration of paroxysmal atrial fibrillation, total ectopic count, and symptom assessments.?RESULTSŚA reduction in the number and duration of episodes of paroxysmal atrial fibrillation was noted following treatment with sotalol and atenolol. There was no difference in frequency of paroxysmal atrial fibrillation during treatment with sotalol or atenolol (median difference 0; 95% confidence interval (CI) 0Āto 1; pĀ= 0.47). There was no difference in total duration of paroxysmal atrial fibrillation (median difference 0Āmin; 95% CI ?1 to 2; pĀ=Ā0.51) or in average duration (median difference 0Āmin; 95% CI 0Āto 1; pĀ=Ā0.31). No difference was found in total ectopic count between sotalol and atenolol (median difference ?123; 95% CI ?362 to 135; pĀ=Ā0.14). Treatments were equally tolerated with no difference in linear analogue scores for symptoms of paroxysmal atrial fibrillation (median difference ?5; 95% CI ?20 to 5; p =Ā0.26) or in all categories of the Nottingham health profile.?CONCLUSIONSŚNo difference was found in terms of ECG or symptomatic control of paroxysmal atrial fibrillation between prescribing sotalol 80Āmg twice daily and atenolol 50Āmg once daily. There was an improvement in paroxysmal atrial fibrillation from baseline following treatment with either sotalol or atenolol.???Keywords: paroxysmal atrial fibrillation; sotalol; atenolol PMID:10409530
Steeds, R; Birchall, A; Smith, M; Channer, K
Independent and additive effects of atenolol and methionine restriction on lowering rat heart mitochondria oxidative stress.
A low rate of mitochondrial ROS production (mitROSp) and a low degree of fatty acid unsaturation are characteristic traits of long-lived animals and can be obtained in a single species by methionine restriction (MetR) or atenolol (AT) treatments. However, simultaneous application of both treatments has never been performed. In the present investigation it is shown that MetR lowers mitROSp and complex I content. Both the MetR and the AT treatments lower protein oxidative modification and oxidative damage to mtDNA and the fatty acid unsaturation degree in rat heart mitochondria. The decrease in fatty acid unsaturation seems to be due, at least in part, to decreases in desaturase and elongase activities or peroxisomal ?-oxidation. Furthermore, the phosphorylation of extracellular signal-regulated kinase (ERK) was stimulated by MetR and AT. The decrease in membrane fatty acid unsaturation and protein oxidation, and the changes in fatty acids and p-ERK showed additive effects of both treatments. In addition, the increase in mitROSp induced by AT observed in the present investigation was totally avoided with the combined MetR + AT treatment. It is concluded that the simultaneous treatment with MetR plus atenolol is more beneficial than either single treatment alone to lower oxidative stress in rat heart mitochondria, analogously to what has been reported in long-lived animal species. PMID:24318105
Sanchez-Roman, Ines; Gomez, Alexia; NaudĒ, Alba; Jove, Mariona; G¾mez, Jose; Lopez-Torres, M¾nica; Pamplona, Reinald; Barja, Gustavo
Formulation and in vitro evaluation of prolonged release floating microspheres of atenolol using multicompartment dissolution apparatus.
The aim of the present work was to prepare floating microspheres of atenolol as prolonged release multiparticulate system and evaluate it using novel multi-compartment dissolution apparatus. Atenolol loaded floating microspheres were prepared by emulsion solvent evaporation method using 3▓ full factorial design. Formulations F1 to F9 were prepared using two independent variables (polymer ratio and % polyvinyl alcohol) and evaluated for dependent variables (particle size, percentage drug entrapment efficiency and percentage buoyancy). The formulation(F8) with particle size of 329 ▒ 2.69 Ąm, percentage entrapment efficiency of 61.33% and percentage buoyancy of 96.33% for 12 h was the of optimized formulation (F8). The results of factorial design revealed that the independent variables significantly affected the particle size, percentage drug entrapment efficiency and percentage buoyancy of the microspheres. In vitro drug release study revealed zero order release from F8 (98.33% in 12 h). SEM revealed the hollow cavity and smooth surface of the hollow microspheres. PMID:23062186
Bhadouriya, Priyanka; Kumar, Manish; Pathak, Kamla
Comparison of Atenolol, Amlodipine, Enalapril, Hydrochlorothiazide, and Losartan for Antihypertensive Treatment in Patients with Obstructive Sleep Apnea
We compared the effects of atenolol (50 mg), amlodipine (5 mg), enalapril (20 mg), hydrochlorothiazide (25 mg), and losartan (50 mg) given in once-daily oral doses on office and ambulatory blood pressures (BPs) in patients with hypertension and obstructive sleep apnea (OSA). Each of 40 randomized patients was treated in se- quence with two of the five agents (balanced incomplete
Receptor occupancy in lumbar CSF as a measure of the antagonist activity of atenolol, metoprolol and propranolol in the CNS.
1. The antagonist activity of atenolol, metoprolol and propranolol in the CNS was estimated by determining the extent to which the drugs occupy animal beta 1- and beta 2-receptors in CSF ex vivo at the time of lumbar puncture. 2. Five CSF and plasma samples were obtained 4 h after drug intake from subjects treated for hypertension with atenolol, 100 mg once daily and five from subjects treated with metoprolol, 50 mg three times daily. Twenty-four samples were obtained 1, 2, 4 or 12 h after drug intake from subjects receiving a single 40 mg dose of propranolol. 3. The receptor occupancy in the samples was determined by adding beta 1-receptors of rabbit lung and beta 2-receptors of rat reticulocytes into the samples and labeling the receptors with a nonselective beta-adrenoceptor antagonist, (-)-[3H]-CGP-12177. 4. Atenolol and metoprolol occupied, as expected, larger fractions of beta 1- than beta 2-receptors in CSF and plasma samples. The receptor fraction occupied by atenolol in CSF was significantly (P < 0.05) lower than that occupied by metoprolol. The differences in occupancy between the drugs in plasma, however, were not statistically significant. 5. Propranolol occupied larger fractions of beta 2- than beta 1-receptors in the samples. Although propranolol concentrations in CSF were only 1/20-1/40 of those in plasma, the receptor occupancy of propranolol in CSF was similar to that in plasma.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:8099803
Kaila, T; Marttila, R
Spectral and mechanistic investigations of ruthenium(III) catalyzed oxidation of atenolol by diperiodatocuprate(III) in aqueous alkaline medium
The kinetics of ruthenium(III) catalyzed oxidation of atenolol by diperiodatocuprate(III) in aqueous alkaline medium at a constant ionic strength of I = 0.10 M has been studied spectrophotometrically at 27░C. The reaction between diperiodatocuprate(III) and atenolol in alkaline medium in presence of ruthenium(III) exhibits 2: 1 stoichiometry (atenolol: diperiodatocuprate(III)). The main products were identified by spot test, IR, NMR, and LC-MS. The reaction is of first order in DPC concentrations and has less than unit order in both ATN and alkali concentrations. The order in ruthenium(III) was unity. Intervention of free radicals was observed in the reaction. Increase in periodate concentration decreases the rate. The oxidation reaction in alkaline medium has been shown to proceed via a ruthenium(III)-atenolol complex, which reacts with monoperiodatocuprate(III) in a rate determining step followed by other fast steps to give the products. Probable mechanism is proposed and discussed. The activation parameters with respect to the slow step of the mechanism and thermodynamic quantities were determined and discussed.
Patil, R. K.; Nandibewoor, S. T.; Chimatadar, S. A.
Comparative Proteomics Analysis of Vascular Smooth Muscle Cells Incubated with S- and R-Enantiomers of Atenolol Using iTRAQ-coupled Two-dimensional LCMS\\/MS
Atenolol is a 1-selective drug, which exerts greater blocking activity on 1-adrenoreceptors than on 2-ad- renoreceptors, with the S-enantiomer being more active than R-enantiomer. The aim of this study was to inves- tigate the proteins with differential protein expression levels in the proteome of vascular smooth muscle cells (A7r5) incubated separately with individual enantiomers of atenolol using an iTRAQ-coupled two-dimensional
Jianjun Sui; Jianhua Zhang; Tuan Lin Tan; Chi Bun Ching; Wei Ning Chen
Spectroscopic and DFT study of atenolol and metoprolol and their copper complexes
IR, Raman and surface-enhanced Raman scattering (SERS) spectra of atenolol (ATE) and metoprolol (MET) were recorded and assigned on the basis of density functional theory (DFT) calculations. A reliable assignment of vibrational IR and Raman bands of the two compounds was possible by a proper choice of models used in quantum chemical calculations. Both molecules are adsorbed to the silver surface mainly through the oxygen atoms and ?-electrons of the phenyl ring. The coordination mode of the metal ions in Cu(II)-ATE and -MET compounds was also derived from IR and EPR spectra. EPR spectra give evidence for a square-planar arrangement around the copper (II) ion in the case of Cu-ATE complex, with a N 2O 2 chromophore. Only oxygen atoms are involved in the cooper coordination for Cu-MET complex, and two types of local symmetries with d and d as ground states for paramagnetic electron coexist.
Cozar, O.; Szab¾, L.; Cozar, I. B.; Leopold, N.; David, L.; C?inap, C.; Chi?, V.
Ocular hypotensive effect of atenolol (Tenormin, I.C.I.). A new beta-adrenergic blocker.
Atenolol (Tenormin or I.C.I. 66082) is a new beta-adrenergic blocking drug, unique in being cardio-selective and in having no intrinsic sympathomimetic or membrane activity. In a controlled double-blind study, a single 50 mg oral dose produced a significant fall in ocular tension for about 7 hours in five patients with definite or suspected glaucoma. The average maximum fall was 35 per cent of the initial pressure; it occurred at 5 hours after oral ingestion. Accordingly neither intrinsic sympathomimetic nor membrane activity can account for all the ocular hypotensive effect of beta blockers in humans. The practical implications for treatment of glaucoma require longer-term investigations some of which are in progress. PMID:240378
Elliot, M J; Cullen, P M; Phillips, C I
The Lifetime Cost Effectiveness of Amlodipine-Based Therapy Plus Atorvastatin Compared with Atenolol Plus Atorvastatin, Amlodipine-Based Therapy Alone and Atenolol-Based Therapy Alone: Results from ASCOT1
Background: ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) showed in hypertensive patients that blood pressure-lowering treatment with an amlodipine-based regimen reduces events compared with an atenolol-based regimen and that atorvastatin was more effective than placebo. Abstract: Objective: To assess the cost effectiveness of four alternative treatment strategies in patients with hypertension and three or more cardiovascular risk factors in the UK (from
Peter Lindgren; Martin Buxton; Thomas Kahan; Neil R. Poulter; Bjrn Dahlf; Peter S. Sever; Hans Wedel; Bengt Jonsson
Electrochemical investigation of atenolol oxidation and detection by using a multicomponent nanostructural assembly of amino acids and gold nanoparticles
A novel nanostructured assembly based on poly(glutamic) acid/cysteine/gold nanoparticles was designed to modify the surface of a glassy carbon electrode (GCE) and used to study the atenolol oxidation. The GCE surface was initially covered by poly(glutamic) acid/cysteine layers followed by covalent attachment of citrate-capped 40 nm-AuNPs. The system excellent electrochemical performance was tested by Linear Sweep Voltammetry and Electrochemical Impedance Spectroscopy and allowed the detection of an atenolol oxidation peak (around +0.65 V/SCE) with a detection limit of 3.9 ū 10-7 M. Such findings could be incorporated in highly sensitive detection technologies of various biological or chemical compounds and molecules.
Pruneanu, Stela; Pogacean, Florina; Grosan, Camelia; Pica, Elena Maria; Bolundut, Liviu Calin; Biris, Alexandru Sorin
Spectroscopic investigations and crystal structure from synchrotron powder data of the inclusion complex of ?-cyclodextrin with atenolol
Inclusion complexes of atenolol with ?-cyclodextrin (?-CD) in aqueous solution have been investigated with 1H NMR and UV-vis spectroscopy. The stoichiometry of this inclusion complex was established to be equimolar (1:1) and its stability constant was determined by UV-vis spectroscopy. The crystal structure of the ?-CD-atenolol (1:1) inclusion compound has been solved from synchrotron powder diffraction data using direct-space search techniques. The crystal structure model and 1H NMR data are in good agreement and, with support of Hyperchem MM+ molecular dynamics results, suggest which protons are likely to be involved in the inclusion process that leads to the supramolecular architecture of this guest-host complex.
Borodi, Gheorghe; Bratu, Ioan; Dragan, Felicia; Peschar, Renķ; Helmholdt, Robert B.; Hernanz, Antonio
A Stability-indicating High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Atenolol and Lercanidipine Hydrochloride in Tablets.
A simple, rapid, precise and accurate isocratic reversed phase stability indicating HPLC method was developed and validated for the simultaneous determination of atenolol and lercanidipine hydrochloride in commercial tablets. The chromatographic separation was achieved on phenomenex Gemini C18 (250ū4.6 mm, 5 ?m) column using a mobile phase consisting of acetonitrile and buffer (20 mM potassium dihydrogen phosphate pH 3.5) in the ratio of (55:45, v/v) at a flow rate of 1.0 ml/min and UV detection at 235 nm. The linearity of the proposed method was investigated in the range of 40-160 ?g/ml (r(2)=0.9995) for atenolol and 8-32 ?g/ml (r(2)=0.9993) for lercanidipine. Degradation products produced as a result of stress studies did not interfere with the detection of atenolol and lercanidipine and the assay can thus be considered stability-indicating. PMID:22707819
Kaila, H O; Ambasana, M A; Thakkar, R S; Saravaia, H T; Shah, A K
A Stability-indicating High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Atenolol and Lercanidipine Hydrochloride in Tablets
A simple, rapid, precise and accurate isocratic reversed phase stability indicating HPLC method was developed and validated for the simultaneous determination of atenolol and lercanidipine hydrochloride in commercial tablets. The chromatographic separation was achieved on phenomenex Gemini C18 (250ū4.6 mm, 5 ?m) column using a mobile phase consisting of acetonitrile and buffer (20 mM potassium dihydrogen phosphate pH 3.5) in the ratio of (55:45, v/v) at a flow rate of 1.0 ml/min and UV detection at 235 nm. The linearity of the proposed method was investigated in the range of 40-160 ?g/ml (r2=0.9995) for atenolol and 8-32 ?g/ml (r2=0.9993) for lercanidipine. Degradation products produced as a result of stress studies did not interfere with the detection of atenolol and lercanidipine and the assay can thus be considered stability-indicating. PMID:22707819
Kaila, H. O.; Ambasana, M. A.; Thakkar, R. S.; Saravaia, H. T.; Shah, A. K.
AvaliańŃo do Resultado Estķtico em Pacientes Submetidas a RessecńŃo de Mama Supranumerßria Axilar Evaluation of the Cosmetic Result in Patients Submitted to Resection of an Axillary Supernumerary Breast
Objetivos: avaliar o grau de satisfańŃo das pacientes submetidas a exķrese de mamas acess¾rias, considerando a estķtica e a taxa de complicań§es. Pacientes e Mķtodos: foram avaliadas 23 pacientes submetidas a tratamento cir·rgico para remońŃo de tecido mamßrio axilar, no Servińo de Mastologia do HC-UFG, entre julho de 1994 e setembro de 1997. A idade variou entre 20 e 49
Marcus Cavalcante de Oliveira; L·cia Taia; Ant¶nio Rosßrio; Leite Filho
Ischemic preconditioning and atenolol on lung injury after intestinal ischemia and reperfusion in rats.
The aim of this study was evaluate the beta blocker atenolol (AT) and ischemic preconditioning (IPC) strategies for tissue protection against systemic effects of intestinal ischemia (I) and reperfusion (R) injury. Forty-two rats were pretreated with AT (1.5 mg Ę kg(-1)), 0.9% saline solution (SS; 0.1ĀmL), or IPC and then subjected to prolonged occlusion of the superior mesenteric artery for 60 minutes leading to I followed or not by 120 minutes of R, according to the group. For IPC, 5 minutes of I prior to 10 minutes of R were established. After this process of I or I-R, the right lung of each animal was adequately prepared for staining with hematoxylin and eosin and subsequent histologic analysis for quantification of inflammatory infiltrate was done. The left lung was frozen and prepared for assessment of oxidative stress by the quantification of thiobarbituric acid-reactivity substances (TBARS). Histologic analysis showed an important inflammatory infiltrate in the I-RĀ+ SS (I-RĀ+ SSĀ= 4.5), which was significantly (PĀ< .05) reduced by IPC (I-RĀ+ IPCĀ= 3.0) or AT (I-RĀ+ ATĀ= 3.0). Likewise, the TBARS levels were decreased by both strategies (I-RĀ+ SSĀ= 0.63; I-RĀ+ IPCĀ= 0.23; I-RĀ+ ATĀ= 0.38; PĀ< .05). Our results showed that AT and IPC attenuate pulmonary lesions caused by intestinal I and R process. PMID:25131055
Bonservizi, W G S; Koike, M K; Saurim, R; Felix, G A A; da Silva, S M; Montero, E F S; Taha, M O
Formulation and optimization of controlled release mucoadhesive tablets of atenolol using response surface methodology.
The aim of the current study was to design oral controlled release mucoadhesive compressed hydrophilic matrices of atenolol and to optimize the drug release profile and bioadhesion using response surface methodology. Tablets were prepared by direct compression and evaluated for bioadhesive strength and in vitro dissolution parameters. A central composite design for 2 factors at 3 levels each was employed to systematically optimize drug release profile and bioadhesive strength. Carbopol 934P and sodium carboxymethylcellulose were taken as the independent variables. Response surface plots and contour plots were drawn, and optimum formulations were selected by feasibility and grid searches. Compressed matrices exhibited non-Fickian drug release kinetics approaching zero-order, as the value of release rate exponent (n) varied between 0.6672 and 0.8646, resulting in regulated and complete release until 24 hours. Both the polymers had significant effect on the bioadhesive strength of the tablets, measured as force of detachment against porcine gastric mucosa (P < .001). Polynomial mathematical models, generated for various response variables using multiple linear regression analysis, were found to be statistically significant (P < .01). Validation of optimization study, performed using 8 confirmatory runs, indicated very high degree of prognostic ability of response surface methodology, with mean percentage error (+/- SD) as -0.0072 +/- 1.087. Besides unraveling the effect of the 2 factors on the various response variables, the study helped in finding the optimum formulation with excellent bioadhesive strength and controlled release. PMID:16584161
Singh, Bhupinder; Chakkal, Sukhwinder Kaur; Ahuja, Naveen
Hiperfenilalaninemia por deficiĻncia de fenilalanina hidroxilase : avaliańŃo da responsividade ao BH4 em pacientes acompanhados no Servińo de Genķtica Mķdica do HCPA e que apresentam controle metab¾lico adequado.
??IntroduńŃo: Estudos recentes, utilizando vßrios protocolos, tĻm demonstrado que pacientes com Hiperfenilalaninemia por deficiĻncia de fenilalanina hidroxilase (HPA-PAH) podem apresentar reduńŃo das concentrań§es plasmßticas deģ (more)
Tatiķle Nalin
[Evaluation by exercise test of effects of a single oral dose of atenolol in patients with stable angina (author's transl)].
Thirty patients with stable angina have been undergone a multistage treadmill test, after a single oral dose of 100 mg of Atenolol, a beta 1 . selective blocking agent, in comparison to a previous test carried out after an identical looking placebo tablet. After placebo all the patients showed ischemic ST segment response (ST depression greater than 1 mm), 25 of them interrupting the test because of anginal pain (20 patients), or of ST depression greater than 3 mm (3 patients), or of ventricular ectopics (one patient), or of fatigue (one patient). After Atenolol 10 patients completed the planned test, 7 of them without ischemic changes of ST. 27 patients (90%) showed increased working capacity with significant reduction of heart-rate (FC), systolic blood pressure (PAS) and their product and of ST depression, either before and during and at the end of exercise. The recovery time of ischemic ECG change has been significantly reduced. The observed increased working capacity is attributed to the reduced myocardial O2 consumption expressed from the reduction of the product FC x PAS. Nevertheless at the end of exercise test after beta-blocking drug this product didn't reach the threshold value at which the test was interrupted in the first test after placebo. The authors discuss the possible cause of this effect of beta-blocking drugs, which could be attributed to a reduction of coronary blood flow and/or to an increased myocardial tension because of increased end diastolic ventricular volume. However the Authors outline that the per cent increases of FC, PAS, and FC x PAS have not been reduced by the Atenolol, unlike their absolute values, at the threshold of angina: the ischemic reveals itself at same levels of per cent increase of the factors of O2 myocardial consumption, the later reaching of threshold values depending on the lower starting values. The advantages of Atenolol as regards the other beta-blocking drugs (better acceptability, stability and duration of action) are outlined too. PMID:7049818
de Divitiis, O; de Simone, G; Maddalena, G; Castaldo, M; Ruggiano, A
A Sensitive and Selective GC¢MS Method for Analysis of Process-Related Genotoxic Impurities in Atenolol
A sensitive GC¢MS method for analysis of residues of allyl chloride (2), 1,3-dichloro-2-propanol (3), and 2,3-dichloro-1-propanol (4), genotoxic impurities in atenolol (1) drug substance, has been developed and validated. Under the optimum conditions used for sample preparation, recovery of\\u000a 2, 3, and 4 from samples spiked at three concentrations, in triplicate, was from 97.1 to 99.3%, from 97.6 to 104.7%,
Yogeshwar Reddy Mamilla; Kista Reddy Chetyala; Ramesh Venna; Raju Gajjela; Kishore Katragadda; Saravanan Govindasamy; Suryanarayana Mulukutla; Debashish Datta
Lifelong treatment with atenolol decreases membrane fatty acid unsaturation and oxidative stress in heart and skeletal muscle mitochondria and improves immunity and behavior, without changing mice longevity.
The membrane fatty acid unsaturation hypothesis of aging and longevity is experimentally tested for the first time in mammals. Lifelong treatment of mice with the ?1-blocker atenolol increased the amount of the extracellular-signal-regulated kinase signaling protein and successfully decreased one of the two traits appropriately correlating with animal longevity, the membrane fatty acid unsaturation degree of cardiac and skeletal muscle mitochondria, changing their lipid profile toward that present in much more longer-lived mammals. This was mainly due to decreases in 22:6n-3 and increases in 18:1n-9 fatty acids. The atenolol treatment also lowered visceral adiposity (by 24%), decreased mitochondrial protein oxidative, glycoxidative, and lipoxidative damage in both organs, and lowered oxidative damage in heart mitochondrial DNA. Atenolol also improved various immune (chemotaxis and natural killer activities) and behavioral functions (equilibrium, motor coordination, and muscular vigor). It also totally or partially prevented the aging-related detrimental changes observed in mitochondrial membrane unsaturation, protein oxidative modifications, and immune and behavioral functions, without changing longevity. The controls reached 3.93 years of age, a substantially higher maximum longevity than the best previously described for this strain (3.0 years). Side effects of the drug could have masked a likely lowering of the endogenous aging rate induced by the decrease in membrane fatty acid unsaturation. We conclude that it is atenolol that failed to increase longevity, and likely not the decrease in membrane unsaturation induced by the drug. PMID:24612513
G¾mez, Alexia; Sßnchez-Roman, Ines; Gomez, Jose; Cruces, Julia; Mate, Ianire; Lopez-Torres, M¾nica; Naudi, Alba; Portero-Otin, Manuel; Pamplona, Reinald; De la Fuente, Monica; Barja, Gustavo
Beta-adrenoceptor blockade and hypoglycaemia. A randomised, double-blind, placebo controlled comparison of metoprolol CR, atenolol and propranolol LA in normal subjects.
1. The effect of 1 week of treatment with propranolol LA (160 mg), atenolol (100 mg) and metoprolol CR (100 mg) on awareness of and the physiological responses to moderate hypoglycaemia were compared with placebo using a randomised, cross-over design in 12 healthy volunteers. 2. All three beta-adrenoceptor antagonists reduced resting heart rate, systolic blood pressure and heart rate responses to submaximal exercise compared with placebo. 3. Under hyperinsulinaemic (60 mu m-2 min-1) clamp conditions, at a blood glucose of 2.5 mmol l-1, atenolol prevented the rise in systolic and atenolol and metoprolol CR prevented the fall in diastolic blood pressure usually associated with hypoglycaemia. At this level of hypoglycaemia, the expected increase in heart rate was inhibited by atenolol but not metoprolol CR. Pre-treatment with propranolol LA resulted in a significant pressor response and a bradycardia during hypoglycaemia. In addition the normal increase in finger tremor was abolished by propranolol LA. 4. During hypoglycaemia all three beta-adrenoceptor blockers augmented sweating compared with placebo but hypoglycaemic symptoms, awareness and slowing of reaction time were the same with drugs and placebo. 5. The rise in plasma adrenaline and other counter-regulatory hormones during hypoglycaemia was enhanced by beta-adrenoceptor blockade. 6. We conclude that beta-adrenoceptor antagonists modify the physiological and hormonal responses to, but do not adversely affect awareness of, moderate hypoglycaemia in healthy volunteers. PMID:1974143
Kerr, D; MacDonald, I A; Heller, S R; Tattersall, R B
Randomized double-blind, placebo-controlled trial of oral atenolol in patients with unexplained syncope and positive upright tilt table test results
The objective of this investigation was the assessment of the response rate of oral atenolol in patients with vasovagal syncope after 1 month of treatment. We randomized into two groups all patients referred to our unit who had had at least one episode of syncope or two episodes of presyncope 1 month before presentation and had a positive isuprel Tilt
Nithi Mahanonda; Kiertijai Bhuripanyo; Charuwan Kangkagate; Kanchana Wansanit; Bang-on Kulchot; Koonlawee Nademanee; Suphachai Chaithiraphan
Clinical efficacy and safety of telmisartan 80 mg once daily vs. atenolol 50 mg once daily in patients with mild-to-moderate hypertension.
The objective of this open-label, parallel-group comparative study was to assess the clinical efficacy and safety of once-daily treatment for 8 weeks with telmisartan 80 mg in comparison with atenolol 50 mg on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in patients with mild-to-moderate hypertension (morning supine SBP 141-199 mmHg, DBP 95-114 mmHg). A total of 58 patients were enrolled. The comparability of the two treatment groups was statistically documented at the beginning of the study. Telmisartan was more effective than atenolol, with a decrease in SBP of 21.7 mmHg vs. 11.8 mmHg (p = 0.03) and a non-significant decrease in DBP of 14.7 mmHg vs. 10.1 mmHg. The safety profiles of both drugs were very similar; both drugs were well tolerated. In conclusion, once-daily telmisartan 80 mg is more effective than once-daily atenolol 50 mg in lowering SBP with no negative chronotropism. Furthermore, telmisartan was as well tolerated as atenolol in the treatment of mild-to-moderate essential hypertension in adults. PMID:15617457
Alcocer, L; Fernßndez-Bonetti, P; Campos, E; Olvera Ruiz, R; Bahena, J; de la Fuente, J J; Segovia-Ayala, C; Dominguez-Henkel, R
Effects of low-dose atenolol on postural and postprandial changes in heart rate, blood pressure, venous plasma catecholamines, and plasma renin activity
The administration of a single dose of atenolol 50 mg 1 h before a standard 3100 kJ cold meal in fasting healthy subjects reduced the supine preprandial heart rate and systolic blood pressure, and blunted the postural and postprandial rises in mean heart rate and systolic blood pressure relative to placebo. It did not affect the preprandial supine diastolic blood
C. de Mey; S. Hansen-Schmidt; D. Enterling; I. Meineke
Este estudo avalia quanto o corpo mķdico do Hospital Dr. DarĒo Contreras de Rep·blica Dominicana conhece, respeita, informa e aplica a Lei Geral de Sa·de em relańŃo aos direitos do paciente Testemunha de Jeovß de negar-se a ser transfundido (respeito a sua autonomia); tambķm se os Testemunhas de Jeovß conhecem a Lei Geral de Sa·de e atķ que ponto tĻm se beneficiado diante dessa proposińŃo. O estudo revelou que nem mķdicos, nem Testemunhas de Jeovß conhecem de fato essa lei. PMID:20689657
Caracteristicas ClĒnicas dos Pacientes Alķrgicos que Vivem em Cidade de Clima Tropical Clinical Characteristics of Allergic Patients Living in a Topical Climate City
Os principais sintomas referidos pelos pacientes: prurido nasal (96,5%), obstruńŃo nasal (93%), espirros (93%), rinorrķia hialina (82,7%), prurido farĒngeo (65,5%), prurido ocular (62%) e lacrimejamento (55%). Os principais achados foram: hipertrofia de cornetos inferiores (69%), palidez mucosa (65,5%), desvio septal (41,3%) e hipertrofia de cornetos mķdios (11%). Os principais alķrgenos que sensibilizaram os pacientes foram: ßcaros da poeira domiciliar (54
Adriano Santana Fonseca; Nilvano Alves Andrade; Viviane Boaventura; Cristiane Britto
Excimer formation in inclusion complexes of ?-cyclodextrin with salbutamol, sotalol and atenolol: spectral and molecular modeling studies.
The inclusion complexation behavior of salbutamol, sotalol and atenolol drugs with ?-cyclodextrin (?-CD) were investigated by UV-visible, fluorometry, time resolved fluorescence, FT-IR, (1)H NMR, SEM and PM3 methods. The above drugs gave a single emission maximum in water where as dual emission in ?-CD. In ?-CD solutions the shorter wavelength fluorescence intensity was regularly decreased and longer wavelength fluorescence intensity increased. Addition of ?-CD to aqueous solutions of drugs resulted into excimer emission. The excimer emission is concluded to be due to a 1:2 inclusion complex between ?-CD and drug. Nanosecond time-resolved studies indicated that all drugs exhibited biexponential decay in solvents and triexponential decay in CD. Investigations of thermodynamic and electronic properties confirmed the stability of the inclusion complex. PMID:22659277
Antony Muthu Prabhu, A; Subramanian, V K; Rajendiran, N
Excimer formation in inclusion complexes of ?-cyclodextrin with salbutamol, sotalol and atenolol: Spectral and molecular modeling studies
The inclusion complexation behavior of salbutamol, sotalol and atenolol drugs with ?-cyclodextrin (?-CD) were investigated by UV-visible, fluorometry, time resolved fluorescence, FT-IR, 1H NMR, SEM and PM3 methods. The above drugs gave a single emission maximum in water where as dual emission in ?-CD. In ?-CD solutions the shorter wavelength fluorescence intensity was regularly decreased and longer wavelength fluorescence intensity increased. Addition of ?-CD to aqueous solutions of drugs resulted into excimer emission. The excimer emission is concluded to be due to a 1:2 inclusion complex between ?-CD and drug. Nanosecond time-resolved studies indicated that all drugs exhibited biexponential decay in solvents and triexponential decay in CD. Investigations of thermodynamic and electronic properties confirmed the stability of the inclusion complex.
Antony Muthu Prabhu, A.; Subramanian, V. K.; Rajendiran, N.
Zero-order release of aspirin, theophylline and atenolol in water from novel methylcellulose glutarate matrix tablets.
A novel hydrocolloidal polymer, methylcellulose glutarate (MC-GA), was prepared by esterifying methylcellulose with glutaric anhydride. The formation of ester was confirmed by FTIR and NMR spectroscopy, DSC and elemental analysis. The physicochemical properties such as, rate of swelling in water, viscosity and hygroscopicity of MC-GA were determined and compared with those of methycellulose A (MC). Aspirin, theophylline and atenolol tablets were compacted on a Carver press using the wet granulation method. Each tablet contained: 200 mg active, 80 mg anhydrous lactose, 8 mg povidone, 4 mg magnesium stearate, 4 mg talc, 50mg MC or MC-GA (drug-to-polymer ratio, 4:1). Contrary to the first-order release profile of all the drugs from the MC matrix tablets, a zero-order release was obtained from the MC-GA matrix tablets in water. PMID:16621361
Khairuzzaman, A; Ahmed, S U; Savva, M; Patel, N K
AvaliańŃo do efeito da administrańŃo de piridostigmina sobre a variabilidade da frequĻncia cardĒaca em pacientes portadores de diabetes mellitus tipo 2 com neuropatia auton¶mica cardiovascular.
??Objetivos/Hip¾tese: A Piridostigmina bloqueia a acetilcolinesterase, promove estimulańŃo colinķrgica e aumenta a variabilidade da freq³Ļncia cardĒaca (VFC) em indivĒduos saudßveis e com insuficiĻncia cardĒaca. Osģ (more)
┬ngela d Avila Harthmann
Randomised, double blind, multicentre comparison of hydrochlorothiazide, atenolol, nitrendipine, and enalapril in antihypertensive treatment: results of the HANE study. HANE Trial Research Group.
OBJECTIVE: To compare the effectiveness and tolerability of hydrochlorothiazide, atenolol, nitrendipine, and enalapril in patients with mild to moderate hypertension. DESIGN: Randomised multicentre trial over 48 weeks with double blind comparison of treatments. SETTING: 48 centres in four countries. PATIENTS: 868 patients with essential hypertension (diastolic blood pressure 95-120 mm Hg) INTERVENTIONS: Initial treatment (step 1) consisted of 12.5 mg hydrochlorothiazide (n = 215), 25 mg atenolol (n = 215), 10 mg nitrendipine (n = 218), or 5 mg enalapril (n = 220) once daily. If diastolic blood pressure was not reduced to < 90 mm Hg within four weeks, doses were increased to 25 mg, 50 mg, 20 mg, 10 mg, respectively, once daily (step 2) and after two more weeks to twice daily (step 3). The eight week titration phase was followed by an additional 40 weeks for patients who had reached the target diastolic pressure. MAIN OUTCOME MEASURES: Blood pressure by means of an automatic device with repeated measurements. RESULTS: After eight weeks the response rate for atenolol (63.7%) was significantly higher than for enalapril (50.0%), hydrochlorothiazide (44.7%), or nitrendipine (44.5%). After one year atenolol was still more effective (48.0%) than hydrochlorothiazide (35.4%) and nitrendipine (32.9%), but not significantly better than enalapril (42.7%). The treatment related dropout rate was higher (P < 0.001) in the nitrendipine group (n = 28). CONCLUSIONS: There is no evidence of superiority for antihypertensive effectiveness or tolerability of the "new" classes of antihypertensives (calcium channel blockers and angiotensin converting enzyme inhibitors). As these drugs are now widely used as treatment of first choice, our results further emphasise the need for studies confirming that they also reduce morbidity and mortality, as has been shown for diuretics and beta blockers. PMID:9251545
Philipp, T.; Anlauf, M.; Distler, A.; Holzgreve, H.; Michaelis, J.; Wellek, S.
Comparison of controlled-onset, extended-release verapamil with amlodipine and amlodipine plus atenolol on exercise performance and ambulatory ischemia in patients with chronic stable angina pectoris
This multicenter, randomized, double-blind, parallel group, placebo lead-in, placebo-controlled study compared the antianginal and anti-ischemic effects of once-daily bedtime dosing of controlled-onset extended-release (COER-24) verapamil to a once-daily morning dosing of amlodipine ▒ atenolol in patients with chronic stable angina. A total of 551 patients with exercise-induced myocardial ischemia and evidence of coronary artery disease were randomized to a 4-week,
William H Frishman; Stephen Glasser; Peter Stone; Prakash C Deedwania; Mary Johnson; T. Daniel Fakouhi
Sensitive spectrophotometric determination of atenolol in pharmaceutical formulations using bromate-bromide mixture as an eco-friendly brominating agent.
Three simple and sensitive spectrophotometric methods are proposed for the determination of atenolol (ATN) in bulk drug and tablets. The methods are based on the bromination of ATN by the bromine generated in situ by the action of the acid on the bromate-bromide mixture followed by the determination of unreacted bromine by reacting with a fixed amount of either meta-cresol purple (MCP) and measuring the absorbance at 540?nm (method A) and 445?nm (method B) or erioglaucine (EGC) and measuring the absorbance at 630?nm (method C). Beer's law is valid within the concentration ranges of 1.0-20.0, 2.0-40.0 and 1.0-8.0??g/mL for method A, method B and method C, respectively. The calculated molar absorptivities were found to be 1.20ū10(4), 4.51ū10(3) and 3.46 ū 10(4)??L/mol Ę cm for method A, method B and method C, respectively. Sandell's sensitivity values, correlation coefficients, limits of detection and quantification are also reported. Recovery results were statistically compared with those of a reference method by applying Student's t- and F-test. The novelty of the present study is the measurement of two different colors using MCP, that is, red-pink color of MCP in acid medium at 540?nm and yellowish-orange color of brominated MCP at 445?nm. PMID:22567567
Prashanth, Kudige N; Basavaiah, Kanakapura
Simultaneous determination of atenolol and amiloride by capillary electrophoresis with capacitively coupled contactless conductivity detection (C4D).
Capillary electrophoresis coupled with a capacitively coupled contactless conductivity detector (CE-C(4)D) has been employed for the determination of the ?-blocker drugs (atenolol and amiloride) in pharmaceutical formulations. 150 mM acetic acid was used as background electrolyte. The influence of several factors (detector excitation voltage and frequency, buffer concentration, applied voltage, capillary temperature, and injection time) was studied. Non-UV absorbing L-valine was used as an internal standard; the analytes were all separated in less than 7 min. The separation was carried out in normal polarity mode at 28 ░C, 25 kV, and using hydrodynamic injection (25 s). The separation was effected in a bare fused-silica capillary 75 ?m ū 52 cm. The CE-C(4)D method was validated with respect to linearity, limit of detection and quantification, accuracy, precision, and selectivity. Calibration curves were linear over the range 5-250 ?g mL(-1) for the studied analytes. The relative standard deviations of intra- and inter-day precisions of migration times and corrected peak areas were less than 6.0%. The method showed good precision and accuracy and was successfully applied to the simultaneous determination of the ?-blocker drugs in different pharmaceutical tablets. PMID:22976091
AL Azzam, Khaldun M; Aboul-Enein, Hassan Y
Mechanical vs intrinsic components in the improvement of brachial arterial compliance. Comparison of the effects of atenolol versus ramipril in hypertensive patients.
The aim of this study was to compare the mechanical and intrinsic effects of an angiotensin converting enzyme inhibitor, vs a beta-blocker, on brachial arterial compliance. In a double blind study, 34 essential hypertensive patients were treated for 3 months with either ramipril 2.5-5.0 mg daily (n = 17, age 57 +/- 7 y, 11 males) or atenolol 50-100 mg daily (n = 17, age 53 +/- 8 y, 11 males). Blood pressure (BP), brachial artery diameter (D), brachial-radial pulse wave velocity (PWV) and effective compliance (Ceff), were measured before and at the end of the study. Isobaric evaluation (Ciso) was performed in the entire population studied at an average mean BP of 110 mmHg. Ramipril significantly reduced BP from 155 +/- 16/94 +/- 6 mmHg to 140 +/- 15/85 +/- 7 mmHg (p < 0.001) without affecting heart rate (HR; 74 +/- 10 vs. 75 +/- 12 bpm). In addition, it significantly improved both PWV (18%; p < 0.001) and arterial compliance (45%; p < 0.001), from which 35% was related to a pressure independent effect (p < 0.01). Atenolol also induced a reduction in both BP (159 +/- 17/96 +/- 10 to 133 +/- 13/81 +/- 8 mmHg; p < 0.001) and HR (76 +/- 10 to 57 +/- 7 bpm; p < 0.001). In a similar way, PWV (11%; p < 0.05) and Ceff (30%; p < 0.05) were significantly improved without significant change in Ciso. This suggests that blood pressure reduction was responsible for compliance improvement. In conclusion, it is suggested that atenolol induces only hemodynamic changes, mediated mainly by BP reduction. In contrast, the improved brachial buffering function observed after ramipril involves not only hemodynamic changes, but also changes mediated by other mechanisms, such as modification of wall structures. PMID:11721319
Armentano, R L; Graf, S; RamĒrez, A J; Espinosa, J D; Brandani, L; Baglivo, H; Sßnchez, R
Biowaiver monographs for immediate release solid oral dosage forms based on biopharmaceutics classification system (BCS) literature data: verapamil hydrochloride, propranolol hydrochloride, and atenolol.
Literature data related to the Biopharmaceutics Classification System (BCS) are presented on verapamil hydrochloride, propranolol hydrochloride, and atenolol in the form of BCS-monographs. Data on the qualitative composition of immediate release (IR) tablets containing these active substances with a Marketing Authorization (MA) in the Netherlands (NL) are also provided; in view of these MA's the assumption was made that these tablets were bioequivalent to the innovator product. The development of a database with BCS-related data is announced by the International Pharmaceutical Federation (FIP). PMID:15236445
Vogelpoel, H; Welink, J; Amidon, G L; Junginger, H E; Midha, K K; M÷ller, H; Olling, M; Shah, V P; Barends, D M
Polimorfismo I/D do gene da enzima conversora de angiotensina e C242T do gene do componente p22phox da NADPH oxidase em pacientes com diabetes tipo 1.
??O sistema renina-angiotensina e o estresse oxidativo tĻm participańŃo importante na fisiopatologia das complicań§es cr¶nicas do diabetes. No presente estudo, foram avaliados 103 pacientes comģ (more)
Roberta Arnoldi Cobas
An Economic Assessment of Losartan-Based Versus Atenolol-Based Therapy in Patients with Hypertension and Left-Ventricular Hypertrophy: Results from the Losartan Intervention For Endpoint reduction (LIFE) Study Adapted to The Netherlands
Background: The Losartan Intervention For End- point reduction (LIFE) study was a randomized, double- blind trial that compared the effects of losartan-based treatment with those of atenolol-based treatment on cardiovascular disease (CVD)-related morbidity and mortality in 9193 patients with hypertension and left- ventricular hypertrophy (LVH). Compared with ateno- lol, losartan reduced the combined risk for CVD-related morbidity and mortality by
Cornelis Boersma; George W. Carides; J arir Atthobari; Aclriaan A. Voors
Synthesis of a nano-sized chiral imprinted polymer and its use as an (S)-atenolol carrier in the bulk liquid membrane.
In this work, nanosized chiral imprinted polymers containing (S)-atenolol ((S)-ATN) selective sites were synthesized by using suspension polymerization in silicon oil. (S)-ATN, methacrylic acid, and ethylene glycol dimethacrylate were used as enantiomerically pure template, functional monomer, and cross-linker, respectively. The prepared chiral imprinted polymers were used as the carrier elements in a bulk liquid membrane (BLM). (S)-ATN transport capability of the chiral imprinted polymers was compared with that of the nonimprinted polymer. It was shown that chiral imprinted polymers could transport (S)-ATN through the BLM more effectively than (R)-ATN, whereas no difference in the facilitated transport was observed between (R)-ATN and (S)-ATN when using nonimprinted polymer particles as the carrier element in the BLM. A kinetic model was proposed for the transportation of (S)-ATN through the chiral imprinted polymers based BLM. It was found that the extraction of ATN from the source to the membrane controls the chiral separation process. It was also found that the pH of source and receiving phases as well as the racemic ATN concentration in source phase had very crucial effect on the chiral separation efficiency. PMID:24771633
Alizadeh, Taher
Multivariate curve resolution-alternating least squares assisted by voltammetry for simultaneous determination of betaxolol and atenolol using carbon nanotube paste electrode.
In the present work differential pulse voltammetry coupled with multivariate curve resolution-alternating least squares (MCR-ALS) was applied for simultaneous determination of betaxolol (Bet) and atenolol (Ate) in 0.20 M Britton-Robinson (B-R) buffer solution at the surface of a multi-walled carbon nanotube modified carbon paste electrode (MWCNT/CPE). Characterization of the modified electrode was carried out by electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). A strategy based on experimental design was followed. Operating conditions were improved with central composite rotatable design (CCRD) and response surface methodology (RSM), involving several chemical and instrumental parameters. Then second order data were built from variable pulse heights of DPV and after correction in potential shift analyzed by MCR-ALS. Analytical parameters such as linearity, repeatability, and stability were also investigated and a detection limit (DL) of 0.19 and 0.29 ?M for Bet and Ate was achieved, respectively. The proposed method was successfully applied in simultaneous determining the two analytes in human plasma. PMID:23632433
Khoobi, Asma; Ghoreishi, Sayed Mehdi; Masoum, Saeed; Behpour, Mohsen
Characteristics of children and young adults with Marfan syndrome and aortic root dilation in a randomized trial comparing atenolol and losartan therapy
Background The Pediatric Heart Network designed a clinical trial to compare aortic root growth and other short-term cardiovascular outcomes in children and young adults with Marfan syndrome randomized to receive atenolol or losartan. We report here the characteristics of the screened population and enrolled subjects. Methods and results Between 2007 and 2011, 21 clinical sites randomized 608 subjects, aged 6 months to 25 years who met the original Ghent criteria and had a body surface area¢adjusted aortic root diameter z-score >3.0. The mean age at study entry was 11.2 years, 60% were male, and 25% were older teenagers and young adults. The median aortic root diameter z-score was 4.0. Aortic root diameter z-score did not vary with age. Mitral valve prolapse and mitral regurgitation were more common in females. Among those with a positive family history, 56% had a family member with aortic surgery, and 32% had a family member with a history of aortic dissection. Conclusions Baseline demographic, clinical, and anthropometric characteristics of the randomized cohort are representative of patients in this population with moderate to severe aortic root dilation. The high percentage of young subjects with relatives who have had aortic dissection or surgery illustrates the need for more definitive therapy; we expect that the results of the study and the wealth of systematic data collected will make an important contribution to the management of individuals with Marfan syndrome. PMID:23622922
Lacro, Ronald V.; Guey, Lin T.; Dietz, Harry C.; Pearson, Gail D.; Yetman, Anji T.; Gelb, Bruce D.; Loeys, Bart L.; Benson, D. Woodrow; Bradley, Timothy J.; De Backer, Julie; Forbus, Geoffrey A.; Klein, Gloria L.; Lai, Wyman W.; Levine, Jami C.; Lewin, Mark B.; Markham, Larry W.; Paridon, Stephen M.; Pierpont, Mary Ella; Radojewski, Elizabeth; Selamet Tierney, Elif Seda; Sharkey, Angela M.; Wechsler, Stephanie Burns; Mahony, Lynn
Hamartoma fibrolipomatoso e macrodistrofia lipomatosa: anßlise dos achados clĒnicos e de imagem em quatro casos, com revisŃo da literatura
O hamartoma fibrolipomatoso neural e a macrodistrofia lipomatosa sŃo doenńas raras, com achados de imagem caracterĒsticos. Radiografias simples, estudos de ressonŌncia magnķtica e prontußrios mķdicos de quatro pacientes foram revisados. Em um paciente, foi realizada cirurgia com confirmańŃo histopatol¾gica. Em trĻs pacientes, os achados clĒnicos e de imagem foram considerados suficientes para o diagn¾stico. Descreve- mos dois casos de macrodistrofia
Rafael Darahem de Souza Coelho; Marcelo Novelino SimŃo; Cl¾vis SimŃo Trad
AdesŃo ao tratamento em pacientes com fibrose cĒstica
Objectives: To evaluate the self-reported degree of adherence to treatment in patients with cystic fibrosis (CF), investigating associations with characteristics of the disease and with the degree of adherence perceived by health professionals. Methods: This was a prospective, cross-sectional study involving patients with CF monitored at a Program for Adults with CF. The degree of adherence was evaluated using a
Paulo de Tarso Roth Dalcin; Greice Rampon; LĒlian Rech Pasin; Gretchem Mesquita Ramon; Claudine Lacerda de Oliveira AbrahŃo; Viviane Ziebell de Oliveira
Los Derechos de los Pacientes del Centro Clnico
Los Derechos de los Pacientes del Centro Cl├Łnico Los Derechos de los Pacientes del Centro Cl├Łnico medir las respuestas de los pacientes al tratamiento. Existen procesos que protegen los derechos de paciente que se observen los derechos fundamentales de la dignidad humana. Esta Declaraci├│n de Derechos
RELACIėN M╔DICO PACIENTE: DERECHOS DEL ADULTO MAYOR
Existen prejuicios en relaci¾n con la vejez, incluso entre los profesionales que se dedican a la gerontologĒa. Uno com·n y peligroso es considerar que los viejos son todos enfermos o discapacitados. La relaci¾n mķdico-paciente es la piedra angular de la prßctica y ķtica mķdicas. Para alcanzar el respeto por los adultos mayores es necesaria una medicina prudente, basada en una prßctica en la cual la reflexi¾n ķtica y clĒnica pueda contribuir. Esto ·ltimo es posible si se hacen valer los derechos del adulto mayor, en particular como paciente para la toma de decisiones. PMID:20379380
Barrantes-Monge, Melba; RodrĒguez, Eduardo; Lama, Alexis
Exercise tolerance with nebivolol and atenolol
Patients treated with beta-blocking agents often complain of fatigue during exercise. Exercise capacity is decreased under this condition. Nebivolol is a new beta1-adrenoceptor antagonist with a particular hemodynamic profile, which might be due to an ancillary property. Five milligrams once daily seems the optimal dose for antihypertensive treatment. In a double-blind, placebo-controlled crossover study, the effects of nebivolol on maximal
Luc M. A. B. Bortel; Marleen A. Baak
Seguridad del paciente en los estudios clĒnicos
Informaci¾n para pacientes, sus familiares y amigos, y el p·blico en general, sobre c¾mo se protegen los derechos y la seguridad de las personas que participan en estudios clĒnicos. Conozca sobre el consentimiento formal, los consejos institucionales de revisi¾n (IRB) y c¾mo se realiza la vigilancia continua de los estudios.
Familiares a cargo de pacientes de cßncer (PDQ«)
Sumario informativo revisado por expertos acerca de los desafĒos que enfrentan los familiares a cargo de los pacientes con cßncer. Este resumen se centra en las funciones tĒpicas y las inquietudes de las personas a cargo del paciente y en las intervenciones ·tiles para esas personas.
Medicina Baseada em EvidĻncias: a arte de aplicar o conhecimento cientĒfico na prßtica clĒnica
RESUMO - Este artigo foi escrito com o objetivo de descrever o conceito de Medicina Baseada em EvidĻncias (MBE) e as competĻncias necessßrias para a sua prßtica. MBE deve ser vista como a integrańŃo da experiĻncia clĒnica com a capacida- de de analisar e aplicar racionalmente a informa- ńŃo cientĒfica ao cuidar de pacientes. A aplicańŃo de mķtodos e estratķgias
A. A. Lopes
Anßlise da assistĻncia nutricional a pacientes disfßgicos hospitalizados na perspectiva de qualidade Analysis of nutritional assistance to dysphagic patients hospitalized from a quality perspective Anßlisis de la asistencia nutricional a los pacientes con disfagia hospitalizados de una perspectiva de la calidad
ReSumo: A disfagia ķ uma condińŃo clĒnica altamente debilitante, que pode acarretar complicań§es graves como pneumonia aspirativa, desidratańŃo e desnutrińŃo. Este estudo teve por objetivo aprimorar a qualidade da assistĻncia nutricional aos pacientes disfßgicos no HU-USP, com aprovańŃo pelo ComitĻ de ╔tica em Pesquisa (CEP 58\\/08). Para tanto, foi estabelecido o perfil nutricional por meio da avaliańŃo antropomķtrica (anßlise a
Patricia Bissoli Sonsin; Ana L·cia Neves Duarte da Silva; Cristiane Bonfim; L·cia Caruso
Suicide risk among inpatients at a university general hospital Risco de suicĒdio em pacientes internados em um hospital geral universitßrio
Objective: To estimate the proportion of inpatients at a university general hospital who are at risk of committing suicide. Method: A random sample of 253 patients (57% males) aged 18 years old or older, admitted to surgical and clinical wards, was assessed using the the Mini International Neuropsychiatric Interview, which has a section that evaluates the risk for suicide. Uni-
Elisabetta Sachsida Colombo; Paula Serra-Azul GuimarŃes; Rachel Esteves Soeiro; Paulo Dalgalarrondo; Neury Josķ Botega
Fisioterapia em pacientes com sĒndrome fĻmoro-patelar: comparańŃo de exercĒcios em cadeia cinķtica aberta e fechada
SUMMARY The aim of this study was to compare the efficacy of muscular strengthening in the functional recovery of patellofemoral syn- drome (PFS) patients. Twenty female patients with PFS were divided into two groups: Group 1 (G1) performing quadriceps femoris strengthening exercises in open kinetic chain (OKC) and Group 2 (G2) in closed kinetic chain (CKC), twice a week for
Cristina Maria Nunes Cabral; ┬ngela Maria de Oliveira Melim; Isabel de Camargo Neves Sacco; Amķlia Pasqual Marques
Anßlise do esquema e imagem corporal em pacientes com esclerose lateral amiotr¾fica
SUMMARY Introduction. The Amyotrophic Lateral Sclerosis (ALS) is fa- tal a neuromuscular disease marked by the committal of the motoneurons of the spinal cord, brain stem and motor cortex causing progressive muscle atrophy. In these patients the de- gree of conscience remains intact, making the individual see himself connected to the environment and a prisoner in his own body. The
CĒntia Citelli de Franńa; Vanessa Rodrigues de Queiroz; Sonia Maria Pereira
AssociańŃo entre o estado nutricional e a ingestŃo dietķtica em pacientes com fibrose cĒstica
Objective: To determine the relationship between nutritional status and dietary intake in patients with cystic fibrosis. Methods: Cross-sectional study involving 85 cystic fibrosis patients between 6 and 18 years of age. Dietary intake was evaluated by the 3-day diet record (weighing the food consumed). The outcome measures were the following nutritional status indicators: weight\\/height (W\\/H%) percentage, body mass index (BMI)
MĒriam Isabel Souza dos Santos Simon; Michele Drehmer; Sķrgio Saldanha Menna-Barreto
EM International. Volume 1
SciTech Connect
It is the intent of EM International to describe the Office of Environmental Restoration and Waste Management`s (EM`s) various roles and responsibilities within the international community. Cooperative agreements and programs, descriptions of projects and technologies, and synopses of visits to international sites are all highlighted in this semiannual journal. Focus on EM programs in this issue is on international collaboration in vitrification projects. Technology highlights covers: in situ sealing for contaminated sites; and remote sensors for toxic pollutants. Section on profiles of countries includes: Arctic contamination by the former Soviet Union, and EM activities with Germany--cooperative arrangements.
Not Available
Quimioterapia de alta dosis prolonga en forma significativa la supervivencia en pacientes con leucemia mieloide aguda
Los resultados preliminares de un estudio clĒnico grande con asignaci¾n al azar de pacientes de 16 a 60 a±os de edad con leucemia mieloide aguda (LMA), un cßncer de la sangre y de la mķdula ¾sea, que no habĒa sido tratada anteriormente, muestran que los pacientes que recibieron una alta dosis de daunorrubicina, un fßrmaco de quimioterapia disponible comercialmente, durante la terapia inicial vivieron mßs que los pacientes que recibieron una dosis normal del mismo fßrmaco.
EMS in the pueblos.
Imagine creating a movie by excerpting scenes from "Dances With Wolves," splicing it with footage from "Code 3" or "Emergency Response" and then flavoring the script with the mystery of a Tony Hillerman novel. A film producer would probably find it quite difficult to choreograph a finished product from such a compilation of material. To hundreds of Native American EMS providers, however, such a movie is played out every day in Indian country. And with this movie come some real-life problems, including trauma, which is the number-one cause of premature death among Native Americans. But a high trauma rate is just one of the challenges facing tribal EMS responders. There's also prolonged response and transport, the problems involved in maintaining the unique culture and standard of care, the challenges of tribal EMS administration and EMS education of Native American students, and the unsure future of Native American EMS. Beyond that, there's the fact that EMS is a s unique to each Indian reservation as are the cultures of the native peoples who reside on these lands. Yet while no two systems are alike, most tribal EMS providers face similar challenges. PMID:10131740
Vigil, M A
Environmental Media Services (EMS)
NSDL National Science Digital Library
Environmental Media Services (EMS) is a nonprofit communications clearinghouse committed to the expansion of media coverage on critical environmental and public health issues. True to their mission, EMS staff "build relationships with top scientists, physicians, and other experts to bring journalists the latest and most credible information." EMS's modest homepage is free of clutter but full of content. While several sections are under construction and updates (currently) appear irregular, a series of available articles provides useful summaries of important environmental news issues over the past six months. Current articles include "The impacts of global warming on the oceans" and "Cool companies," among others.
Miesto ir kaimo pacient? pasitenkinimas pirmine odontologine prie×i?ra.
??Darbo tikslas. ?vertinti miesto ir kaimo pacient? pasitenkinim? pirmine odontologine prie×i?ra KaiÜiadori? pirmin?s sveikatos prie×i?ros centre. U×daviniai. ?vertinti pacient? pasitenkinim? pirmine odontologine prie×i?ra; nustatyti veiksnius,ģ (more)
Kere×yt?,; Aurelija
Familiares a cargo de pacientes de cßncer: funciones y desafĒos (PDQ«)
CARACTERIZAŪ├O DOS ACIDENTES DE TR┬NSITO ENVOLVENDO CRIANŪAS E ADOLESCENTES INTERNADOS EM UM HOSPITAL P┌BLICO TERCI┴RIO The characterization of traffic accidents involving children and adolescents admitted to a public tertiary hospital
RESUMO Objetivo: Investigar os fatores relacionados a acidentes de trŌnsito envolvendo crianńas e adolescentes internados em um hospital p·blico tercißrio da cidade de Fortaleza e o grau de conhecimento de seus pais ou responsßveis sobre os direitos dos acidentados. Mķtodos: Tratou-se de um estudo de natureza descritiva, observacional e com abordagem quantitativa, cuja amostra constituiu-se de 45 pacientes internados. As
Dantas MMP; Silva AC; Gurgel LA
EM Radiation Program
The EM Radiation program displays the electric field vectors (in the x-y plane) and magnetic field contours (for the field in the z direction) calculated from the Lienard-Wiechert potentials for a charged particle. The default scenario shows the resulting radiation from a charged particle in simple harmonic motion. Additional particle trajectories can be specified using the Display | Switch GUI menu item. EM Radiation is an Open Source Physics program written for the teaching of electromagnetism. It is distributed as a ready-to-run (compiled) Java archive. Double clicking the em_radiation.jar file will run the program if Java is installed. Other electromagnetism programs are also available. They can be found by searching ComPADRE for Open Source Physics, OSP, or electromagnetism.
Christian, Wolfgang
Gleevec disminuye la recidiva del cßncer en pacientes con tumor estromal gastrointestinal primario
Los resultados preliminares de un estudio clĒnico grande aleatorio y controlado con placebo, en pacientes con tumor estromal gastrointestinal (GIST) primario, un tipo de tumor que por lo general se encuentra en el est¾mago o en el intestino delgado, demostraron que los pacientes a los que se administr¾ mesilato de imatinib (Gleevec«) luego de la extirpaci¾n total de su tumor tuvieron una probabilidad significativamente menor de padecer una recidiva del cßncer en comparaci¾n con aquellos a los que no se administr¾ imatinib.
AvaliańŃo da aerańŃo e edema pulmonar por meio de tomografia computadorizada em pacientes submetidos a revascularizańŃo do miocßrdio.
??Introduction: Hypoxemia is a frequent complication after coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB), usually attributed to atelectasis. Using computed tomography (CT), weģ (more)
Roseny dos Reis Rodrigues
Nursing care of patients on corticosteroid pulse therapy AssistĻncia de enfermagem ao paciente em pulsoterapia com corticoster¾ide
introduction: Intravenous pulse therapy with corticosteroid involves administration of high doses (starting from 1 g \\/day), given on three or more consecutive days. Because of possible adverse effects, it is recommended that patients stay at hospital during administration of pulse therapy. Monitoring of vital signs can early identify these adverse effects and allow efficient intervention assuring patient's safety. Uniform nursing
Deborah Rozencwajg; Carla Fßtima; PaixŃo Nunes; Luciane Midory Sakuma; Clßudia Regina Laselva; Bartira Aguiar Roza
The EM Earthquake Precursor
Many attempts have been made to determine a sound forecasting method regarding earthquakes and warn the public in turn. Presently, the animal kingdom leads the precursor list alluding to a transmission related source. By applying the animal-based model to an electromagnetic (EM) wave model, various hypotheses were formed, but the most interesting one required the use of a magnetometer with a differing design and geometry. To date, numerous, high-end magnetometers have been in use in close proximity to fault zones for potential earthquake forecasting; however, something is still amiss. The problem still resides with what exactly is forecastable and the investigating direction of EM. After the 1989 Loma Prieta Earthquake, American earthquake investigators predetermined magnetometer use and a minimum earthquake magnitude necessary for EM detection. This action was set in motion, due to the extensive damage incurred and public outrage concerning earthquake forecasting; however, the magnetometers employed, grounded or buried, are completely subject to static and electric fields and have yet to correlate to an identifiable precursor. Secondly, there is neither a networked array for finding any epicentral locations, nor have there been any attempts to find even one. This methodology needs dismissal, because it is overly complicated, subject to continuous change, and provides no response time. As for the minimum magnitude threshold, which was set at M5, this is simply higher than what modern technological advances have gained. Detection can now be achieved at approximately M1, which greatly improves forecasting chances. A propagating precursor has now been detected in both the field and laboratory. Field antenna testing conducted outside the NE Texas town of Timpson in February, 2013, detected three strong EM sources along with numerous weaker signals. The antenna had mobility, and observations were noted for recurrence, duration, and frequency response. Next, two directional techniques were employed, resulting in three mapped, potential epicenters. The remaining, weaker signals presented similar directionality results to more epicentral locations. In addition, the directional results of the Timpson field tests lead to the design and construction of a third prototype antenna. In a laboratory setting, experiments were created to fail igneous rock types within a custom-designed Faraday Cage. An antenna emplaced within the cage detected EM emissions, which were both reproducible and distinct, and the laboratory results paralleled field results. With a viable system and continuous monitoring, a fracture cycle could be established and observed in real-time. Sequentially, field data would be reviewed quickly for assessment; thus, leading to a much improved earthquake forecasting capability. The EM precursor determined by this method may surpass all prior precursor claims, and the general public will finally receive long overdue forecasting.
Jones, K. B., II; Saxton, P. T.
Carcinoma espinocelular cutŌneo em cŃes.
??DissertańŃo de Mestrado Integrado em Medicina Veterinßria O Carcinoma Espinocelular (CEC) ķ uma neoplasia com origem nos queratin¾citos e representa aproximadamente 5% das neoplasias cutŌneasģ (more)
Moura, InĻs da Costa
Identified EM Earthquake Precursors
Many attempts have been made to determine a sound forecasting method regarding earthquakes and warn the public in turn. Presently, the animal kingdom leads the precursor list alluding to a transmission related source. By applying the animal-based model to an electromagnetic (EM) wave model, various hypotheses were formed, but the most interesting one required the use of a magnetometer with a differing design and geometry. To date, numerous, high-end magnetometers have been in use in close proximity to fault zones for potential earthquake forecasting; however, something is still amiss. The problem still resides with what exactly is forecastable and the investigating direction of EM. After a number of custom rock experiments, two hypotheses were formed which could answer the EM wave model. The first hypothesis concerned a sufficient and continuous electron movement either by surface or penetrative flow, and the second regarded a novel approach to radio transmission. Electron flow along fracture surfaces was determined to be inadequate in creating strong EM fields, because rock has a very high electrical resistance making it a high quality insulator. Penetrative flow could not be corroborated as well, because it was discovered that rock was absorbing and confining electrons to a very thin skin depth. Radio wave transmission and detection worked with every single test administered. This hypothesis was reviewed for propagating, long-wave generation with sufficient amplitude, and the capability of penetrating solid rock. Additionally, fracture spaces, either air or ion-filled, can facilitate this concept from great depths and allow for surficial detection. A few propagating precursor signals have been detected in the field occurring with associated phases using custom-built loop antennae. Field testing was conducted in Southern California from 2006-2011, and outside the NE Texas town of Timpson in February, 2013. The antennae have mobility and observations were noted for recurrence, duration, and frequency response. At the Southern California field sites, one loop antenna was positioned for omni-directional reception and also detected a strong First Schumann Resonance; however, additional Schumann Resonances were absent. At the Timpson, TX field sites, loop antennae were positioned for directional reception, due to earthquake-induced, hydraulic fracturing activity currently conducted by the oil and gas industry. Two strong signals, one moderately strong signal, and approximately 6-8 weaker signals were detected in the immediate vicinity. The three stronger signals were mapped by a biangulation technique, followed by a triangulation technique for confirmation. This was the first antenna mapping technique ever performed for determining possible earthquake epicenters. Six and a half months later, Timpson experienced two M4 (M4.1 and M4.3) earthquakes on September 2, 2013 followed by a M2.4 earthquake three days later, all occurring at a depth of five kilometers. The Timpson earthquake activity now has a cyclical rate and a forecast was given to the proper authorities. As a result, the Southern California and Timpson, TX field results led to an improved design and construction of a third prototype antenna. With a loop antenna array, a viable communication system, and continuous monitoring, a full fracture cycle can be established and observed in real-time. In addition, field data could be reviewed quickly for assessment and lead to a much more improved earthquake forecasting capability. The EM precursors determined by this method appear to surpass all prior precursor claims, and the general public will finally receive long overdue forecasting.
Jones, Kenneth, II; Saxton, Patrick
College of Engineering EM Engineering Mechanics
College of Engineering EM Engineering Mechanics KEY: # = new course * = course changed = course or concur: MA 213. EM 302 MECHANICS OF DEFORMABLE SOLIDS. (3 of Engineering or consent of chairperson, and EM 221; prereq or concur: MA 214. EM 313 DYNAMICS. (3
MacAdam, Keith
Investimento ambiental em ind·strias sujas e intensivas em recursos naturais e energia
O crescimento industrial brasileiro, a partir do final dos anos setenta, ocorreu com o aumento da participańŃo de ind·strias intensivas em recursos naturais, em detrimento da participańŃo de ind·strias intensivas em trabalho e dos setores intensivos em atividades tecnol¾gicas mais complexas. Essas transformań§es, tornando o setor de bens intermedißrios dominante na estrutura industrial, implicaram em considerßveis mudanńas tanto de ordem
Frederico Cavadas Barcellos; Jurandir Carlos de Oliveira; Paulo Gonzaga Mibielli de Carvalho
Turismo Nßutico em Angra dos Reis ¢ RJ : a sustentabilidade em questŃo.
??DissertańŃo (mestrado)ŚUniversidade de BrasĒlia, Centro de Desenvolvimento Sustentßvel, 2011. O turismo estß em franca expansŃo e se desenvolvendo a taxas bastante significativas no Brasil. Emģ (more)
Medeiros, Mßrcio Bastos
El NCI inicia un estudio para evaluar la utilidad de la secuenciaci¾n genķtica para mejorar los resultados en los pacientes
El Instituto Nacional del Cßncer (NCI) lanzarß este mes un estudio clĒnico piloto denominado M-PACT con la finalidad de evaluar si el tratamiento asignado seg·n mutaciones genķticas especĒficas puede brindar beneficios a pacientes con tumores s¾lidos metastßsicos.
Radioterapia extema radical en cßncer infiltrante de vejiga en pacientes gerißtricos con contraindicaci¾n mķdica para la cirugĒa: experiencia institucional
ResumenĀĀSe analiza retrospectivamente la tolerancia y el control tumoral en pacientes con cßncer infiltrante de vejiga cuya ·nica\\u000a alternativa terapķutica radical es la radioterapia externa.\\u000a \\u000a Cuarenta y siete pacientes (3 mujeres y 44 varones), con contraindicaci¾n para cistectomĒa, fueron tratados con radioterapia\\u000a externa con intenci¾n curativa. Cuarenta (85%) tenĒan una edad al diagn¾stico ? 70 a±os. Nueve presentaban performance status
Ra·l Matute MartĒn; Arnaldo Alvarado Astudillo; Nuria E. MartĒnez Moreno; Josķ A. Arranz Arija; Marina G¾mez EspĒ; Dolores de la Mata Moya; Esperanza Lozano Guerra; Javier Serrano Andreu; Rafael Herranz Crespo; Manuel Felipe A. Calvo
Populań§es estelares em galßxias HII
Analisamos o conte·do estelar de 74 galßxias HII a partir do contĒnuo observado nos espectros ¾pticos dessas galßxias, utilizando mķtodos de sĒntese de populańŃo estelar. Descobrimos que todas as galßxias para as quais encontramos soluń§es contĻm uma populańŃo estelar velha que domina a massa estelar, e numa maioria dessas tambķm encontramos evidĻncia de uma populańŃo de idade intermediaria alķm da gerańŃo jovem que estß se formando agora. ConcluĒmos que a formańŃo estelar dessas galßxias se realiza em surtos individuais, Esses surtos sŃo interrompidos por longos perĒodos de inatividade, com os primeiros consumindo a maior parte do gßs. Sugerimos, portanto, que as galßxias HII sejam galßxias anŃs normais flagradas em um perĒodo de surto.
Westera, P.; Cuisinier, F.; Telles, E.; Kehrig, C.
Burning the EMS candle. EMS shifts and worker fatigue.
Has coffee become your best friend? Do you sleep only in your dreams? Is your bed merely an illusion? If so, you are not alone; sleep deprivation is a fact of life for many EMS personnel. Though widely accepted, isn't it time that we question the effects of those long days and nights? PMID:10116022
McCallion, R; Fazackerley, J
Programa de Ps-Graduao em Economia
1 Programa de P├│s-Gradua├¦├Żo em Economia PPG-ECO Universidade de Bras├Łlia UnB UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 1/2014 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA PARA O CURSO DE MESTRADO PROFISSIONAL EM ECONOMIA ┬Ł ├üREA DE CONCENTRA├?├?O
Maier, Rudolf Richard
The European Mobile System (EMS)
NASA Technical Reports Server (NTRS)
The European Space Agency is presently procuring an L band payload in order to promote a regional European L band system coping with the specific needs of the European market. The payload, and the two communications systems to be supported, are described below. The potential market for EMS in Europe is discussed.
Jongejans, A.; Rogard, R.; Mistretta, I.; Ananasso, F.
WRF-EMS Aviation Products
This lesson illustrates how numerical guidance from the Weather Research and Forecasting Model - Environmental Modeling System (WRF-EMS) can be added to surface observations, satellite graphics, and conceptual models of important aviation phenomena, to produce TAFs. Specifically, the lesson describes how visibility, cloud ceilings, and the flight categories variables provide values for aviation forecasts in Africa.
Anormalidades oculares em 20 pacientes com sĒndrome de Williams-Beuren Ocular abnormalities in 20 patients with Williams-Beuren syndrome Anormalidades oculares en 20 pacientes con sĒndrome de Williams-Beuren
Objective: to alert pediatricians, geneticists and ophthalmologists to ophthalmologic aspects of Williams-Beuren syndrome (WBS). Casuistic and Methods: there was performed an ophthalmological evaluation in 20 patients (11M:9F) 9.5 years-old aged (average) range - 5 to 17 years-old. Results: the following ocular anomalies were observed: punctate opacities in the lens (84%), strabismus (45%), stellate iris pattern (42%), retinal vessel tortuosity (42%),
Sofia Mizuho; Miura Sugayama; Luiz Carlos Ferreira de Sß; Kikue Terada Abe; Clßudio Leone; Maria de Lourdes; Lopes Ferrari Chauffaille
Angus Robichaud's Reel G Em D A Bm D7
Angus Robichaud's Reel 4 4 D G A D D G A D 3 3 G Em D A Bm D7 3 3 G Em D A D Animas Reel Bernie Waugh 4 4 3 3 G D G Bm Em C Am C D G D G Bm Em C Am D G The Arkansas Traveler 4 2 D G A D Em A 3D G A D Em G A D D G D A Bm Em A D G D A Em G A D #12;Asher Rodney Miller 4 4 D Em F#m G A D Em G A D A D1 2
Doyle, Peter
Angus Robichaud's Reel 4 4 D G A D D G A D 3 3 G Em D A Bm D7 3 3 G Em D A D Animas Reel Bernie Waugh 4 4 3 3 G D G Bm Em C Am C D G D G Bm Em C Am D G The Arkansas Traveler 4 2 D G A D Em A 3 D G A D Em G A D D G D A Bm Em A D G D A Em G A D #12; Asher Rodney Miller 4 4 D Em F#m G A D Em G A D A D 1
Anßlisis de componentes cognoscitivos y psiquißtricos en pacientes con demencia frontotemporal y alzheimer / Analysis of cognitive and psychiatric components in patients with frontotemporal dementia and Alzheimer.
??Reyes Gavilßn, Pablo Alexander (2010) Anßlisis de componentes cognoscitivos y psiquißtricos en pacientes con demencia frontotemporal y alzheimer / Analysis of cognitive and psychiatric componentsģ (more)
Reyes Gavilßn, Pablo Alexander
Efectos del tratamiento con anti-TNF-?, infliximab, sobre la resistencia insulĒnica, adipocinas (visfatina, leptina, adiponectina, resistina y apelina) y angiopoyetina-2 en pacientes con espondilitis anquilosante.
??RESUMEN: La Espondilitis Anquilosante (EA) es una enfermedad inflamatoria cr¾nica que afecta fundamentalmente a la columna vertebral produciendo sacroileĒtis. Estos pacientes presentan una aterogķnesis aceleradaģ (more)
Miranda Filloy, Josķ Alberto
estudio recomendado aquellos pacientes sĒntomas especĒficos tales como: dolor extremidades pseudoclaudicaci¾n sĒntomas atĒpicos. travķs informaci¾n espero pueda enriquecer formaci¾n quieran leerlos.
EPA Pesticide Factsheets
Search instead for estudio recomendado aquellos pacientes sĒntomas especĒficos tales como: dolor extremidades pseudoclaudicaci¾n sĒntomas atĒpicos. travķs informaci¾n espero pueda enriquecer formaci¾n quieran leerlos. ?
Effect of amlodipine compared to atenolol on small arteries of previously untreated essential hypertensive patients
In a previous retrospective study, long-term treatment of essential hypertensive patients with a slow-release calcium channel blocker resulted in normal resistance artery structure and endothelial function, which did not occur with a ?-blocker. In the present prospective study, 19 previously untreated essential hypertensive patients (aged 47 ▒ 2 years, 75% male) were treated for 1 year in a double-blind randomized
Ernesto L Schiffrin; Qian Pu; Jeong Bae Park
DEPARTAMENTO DE ECONOMIA MESTRADO EM ECONOMIA EDITAL DE CONVOCA├?├?O ┬Ł 2014 Est├Żo abertas as inscri├¦├Ąes para o Mestrado em Economia da PUC-Rio, a iniciar-se em janeiro de 2014. Para candidatos residentes no Brasil: A admiss├Żo ├® feita atrav├®s do Exame Nacional de Economia, organizado pela ANPEC
DEPARTAMENTO DE ECONOMIA DOUTORADO EM ECONOMIA EDITAL DE CONVOCA├?├?O ┬Ł 2014 Est├Żo abertas as inscri├¦├Ąes para o Doutorado em Economia da PUC-Rio, a iniciar-se em janeiro de 2014. O per├Łodo de inscri├¦├Ąes ]: Departamento de Economia [ref.: Candidatura ao Doutorado] Pontif├Łcia Universidade Cat├│lica do Rio de Janeiro
Lietuvos teritorijos ×em?s plutos deformacij? ir seismotektoninio potencialo ryÜys
Lietuvoje yra statini?, kelian?i? ekologinio pavojaus gr?sm? (Ignalinos atomin? elektrin?, Ma×eiki? naftos perdirbimo ?mon?, chemijos gamyklos Jonavoje bei K?dainiuose ir pan.). Seisminiai ?vykiai gali sutrikdyti Üi? ?moni? veikl? ir net lemti didel? pavoj? aplinkai, t. y. gali b?ti sukelta didel? aplinkos tarÜa chemin?mis bei radioaktyviosiomis med×iagomis. Seisminius ?vykius lemia teritorijos seismotektoninis potencialas. Seismotektoninis potencialas ir Äem?s plutos deformacijos yra tarpusavyje susij? rei\\vskiniai, kuriuos sukelia da×nai tie patys giluminiai procesai Äem?s gelm?se. Äem?s plutos deformacij? tyrimas yra vienas iÜ informacijos Üaltini? prognozuojant teritorijos seismotektonin? aktyvum?. Straipsnyje nagrin?jamos Äem?s plutos horizontaliosios deformacijos, nustatomi Äem?s plutos ?tempi? poky?iai Lietuvos teritorijoje pagal GPS matavim? duomenis. Atlikus tyrimus pagal pateikiam? Äem?s plutos horizontali?j? deformacij? ir ?tempi? tyrimo metodik?, gauti nauji horizontali?j? deformacij? charakteristik? bei ?tempi? poky?i? rezultatai ir nustatytos j? s?sajos su seismotektoniniu potencialu.
Zakarevi?ius, Algimantas; Stanionis, Arminas; Levinskait?, Daiva
7 CFR 1945.20 - Making EM loans available.
Code of Federal Regulations, 2012 CFR
...2012-01-01 false Making EM loans available. 1945.20 Section 1945.20 Agriculture Regulations of the Department...CONTINUED) EMERGENCY Disaster Assistance-General ¦ 1945.20 Making EM loans available. EM...
AvaliańŃo da prevalĻncia de sofrimento psĒquico em pacientes com dermatoses do espectro dos transtornos psicocutŌneos* Assessment of the prevalence of psychological distress in patients with psychocutaneous disorder dermatoses
B ACKGROUND - It is estimated that emotional aspects are involved in one third of patients with skin diseases. OBJECTIVE - To verify the prevalence of psychological distress in patients with psychocutaneous disorder dermatoses (PDD), as well as to relate the degree of psychological distress to the disease, duration of disease progression, gender and age of patients. M ETHODS -
Maria-Laura V. V. Taborda; Elaine Silveira Freitas
Estudo do polimorfismo C677T do gene da metilenotetrahidrofolato redutase (MTHFR) em pacientes com mucosite de trato gastrointestinal ap¾s transplante alogĻnico de medula ¾ssea.
??Oral mucositis remains an important side-effect and life-threatening complication of hematopoietic stem cell transplantation. It can occurs in 100% of patients underwenting allogeneic stem cellģ (more)
Fabio Luiz Coracin
SUMMARY Renal transplants are been carried out in an increasing number of elderly people and patients with diabetes who alsohavewidespreadaterosclerothiclesionswichisenhancedbyprolongedhemodialysis,arterialhypertension and other risk factors. The most common is the aneurysm of the abdominal aorta. There are currently several different opinions about the technique to adopt for the prevention of the ischaemic damage to the transplanted kidney. In this article, we
LuĒs Henrique; Gil Franńa; Ricardo Cķsar; Rocha Moreira; Simone Dyniewicz; Cristiano Marcos; D'Alcantara Schmitt; Alessandra Vedolin; Marcelo Barros; Caroline Gomes Bredt; Josiane Souza
Padr§es ventilat¾rios na espirometria em pacientes adolescentes e adultos com fibrose cĒstica* Respiratory patterns in spirometric tests of adolescents and adults with cystic fibrosis
Objective: To evaluate spirometric patterns of respiratory disorders and their relationship with functional severity and maximal expiratory flows at low lung volumes in patients with cystic fibrosis (CF). Methods: A retrospective cross-sectional study including adolescents and adults with CF. All of the patients were submitted to spirometry. Patients were classified as having preserved respiratory function, obstructive lung disease (OLD), OLD
Bruna Ziegler; Paula Maria Eidt Rovedder; Paulo de Tarso; Roth Dalcin; Sķrgio Saldanha Menna-Barreto
Pneumot¾rax espontŌneo simultŌneo bilateral em um paciente adulto com fibrose cĒstica* Simultaneous bilateral spontaneous pneumothorax in an adult patient with cystic fibrosis
Pneumothorax is a common complication in cystic fibrosis and is associated with worsening of lung function. However, bilateral simultaneous pneumothorax in cystic fibrosis is a rare condition. We describe the case of a 17-year-old female with cystic fibrosis who presented with spontaneous pneumothorax. Clinically, she presented right-sided chest pain and progressive breathlessness. The pneumothorax failed to resolve after the initial
Kamlesh Mohan; Martin James Ledson; Martin John Walshaw; Edson Marchiori
Perception of disease severity in adult patients with cystic fibrosis* PercepńŃo da gravidade da doenńa em pacientes adultos com fibrose cĒstica
Objective: To evaluate the perception of disease severity in patients with cystic fibrosis (CF), investigating its relationship with clinical score, radiographic score, respiratory function tests, adherence to treatment and perception of self-care practices. Methods: Prospective, cross-sectional study involving CF patients treated in a program for adults with CF. The perception of disease severity, adherence to treatment and reported self-care practices
Paulo de Tarso; Roth Dalcin; Greice Rampon; LĒlian Rech Pasin; Sinara CorrĻa Becker; Viviane Ziebell de Oliveira
PercepńŃo da gravidade da doenńa em pacientes adultos com fibrose cĒstica* Perception of disease severity in adult patients with cystic fibrosis
Artigo Original Capacidade submßxima de exercĒcio em pacientes adolescentes e adultos com fibrose cĒstica* Submaximal exercise capacity in adolescent and adult patients with cystic fibrosis
Objective: To determine the submaximal exercise capacity of patients with cystic fibrosis (CF) by means of the 6-minute walk test (6MWT), correlating the results with clinical score, nutritional status, radiographic score, and pulmonary function tests. Methods: This was a prospective, cross-sectional study involving patients aged 16 or older enrolled in a program for adults with CF. The patients were submitted
Bruna Ziegler; Paula Maria Eidt Rovedder; Janice Luisa Lukrafka; Claudine Lacerda Oliveira; Sķrgio Saldanha Menna-Barreto; Paulo de Tarso; Roth Dalcin
Emprego de metilfenidato para o tratamento de dķficit cognitivo em paciente com seq³ela de traumatismo cranioencefßlico Methylphenidate for the treatment of cognitive deficit in traumatic brain injury
Traumatic brain injury is the main cause of death and disability among young people. Attention deficits and executive dysfunction occur frequently after prefrontal cortex damage. The authors report a case of methylphenidate use for the treatment of cognitive deficits in a patient with a two-year evolution of traumatic brain injury. After two months, the patient reported significant improvement in his
Fßbio Lopes Rocha; Leandro F. Malloy-Dini; Clßudia Hara
Binge eating disorder, anxiety, depression and body image in grade III obesity patients CompulsŃo alimentar peri¾dica, ansiedade, depressŃo e imagem corporal em pacientes com obesidade grau III
Introduction: The objective of this study was to assess the frequency of Binge Eating Disorder (BED) or Binge Eating episodes (BINGE), anxiety, depression and body image disturbances in severely obese patients seeking treatment for obesity. Method: We assessed 50 patients (10M and 40F) with Body Mass Index (BMI) between 40 and 81.7 Kg\\/m2 (mean 52.2▒9.2 Kg\\/m2) and aging from 18
Maria Isabel R Matos; Luciana S Aranha; Alessandra N Faria; Sandra R G Ferreira; Josuķ Bacaltchuck; Maria Teresa Zanella
EMS communications development: History and commentary
The history of emergency medical services (EMS) communication systems development from the FCC's first allocation of frequencies for hospitals and ambulances up to the present is discussed. Up until the late 1960's EMS communication systems were virtually nonexistent. Most early networks were developed by hospital associations for coordination of hospital disaster operations. Many significant changes were seeded in 1966. By
B. A. Smith
School Budget Hold'em Facilitator's Guide
"School Budget Hold'em" is a game designed to help school districts rethink their budgeting process. It evolved out of Education Resource Strategies' (ERS) experience working with large urban districts around the country. "School Budget Hold'em" offers a completely new approach--one that can turn the budgeting process into a long-term visioningģ
Education Resource Strategies, 2012
EM international activities. February 1997 highlights
EM International Highlights is a brief summary of on-going international projects within the Department of Energy`s Office of Environmental Management (EM). This document contains sections on: Global Issues, activities in Western Europe, activities in central and Eastern Europe, activities in Russia, activities in Asia and the Pacific Rim, activities in South America, activities in North America, and International Organizations.
Contributo para a caracterizańŃo molecular de echinococcus granulosus em Portugal.
??Mestrado em CiĻncias Biomķdicas, Especialidade de Biologia Molecular em Medicina Tropical e Internacional A Equinococose/hidatidose ¢ doenńa causada pela fase larvar (hidßtide ¢ vulgarmente conhecidaģ (more)
Beato, SĒlvia Filipa Alves
Project X RFQ EM Design
Project X is a proposed multi-MW proton facility at Fermi National Accelerator Laboratory (FNAL). The Project X front-end would consist of an H- ion source, a low-energy beam transport (LEBT), a CW 162.5 MHz radio-frequency quadrupole (RFQ) accelerator, and a medium-energy beam transport (MEBT). Lawrence Berkeley National Laboratory (LBNL) and FNAL collaboration is currently developing the designs for various components in the Project X front end. This paper reports the detailed EM design of the CW 162.5 MHz RFQ that provides bunching of the 1-10 mA H- beam with acceleration from 30 keV to 2.1 MeV.
Romanov, Gennady; /Fermilab; Hoff, Matthew; Li, Derun; Staples, John; Virostek, Steve; /LBNL
EM International, July 1994, Volume 2
The Office of Environmental Management (EM) at the Department of Energy (DOE) is seeking out and leveraging foreign technology, data, and resources in keeping with EM`s mandate to protect public health and the environment through the safe and cost-effective remediation of the Department`s nuclear weapons sites. EM works closely with foreign governments, industry, and universities to obtain innovative environmental technologies, scientific and engineering expertise, and operations experience that will support EM`s objectives. Where appropriate, these international resources are used to manage the more urgent risks at our sites, secure a safe workplace, help build consensus on critical issues, and strengthen our technology development program. Through international agreements EM engages in cooperative exchange of information, technology, and individuals. Currently, we are managing agreements with a dozen countries in Europe, Latin America, and Asia. These agreements focus on environmental restoration, waste management, transportation of radioactive wastes, and decontamination and decommissioning. This publication contains the following articles: in situ remediation integrated program; in-situ characterization and inspection of tanks; multimedia environmental pollutant assessment system (MEPAS); LLNL wet oxidation -- AEA technology. Besides these articles, this publication covers: EU activities with Russia; technology transfer activities; and international organization activities.
Kinesiology Undergraduate Student Learning Outcomes (EMS)
1 Kinesiology Undergraduate Student Learning Outcomes (EMS) Kinesiology Undergraduate Student Learning Outcomes (PE) Kinesiology Graduate Program 1. Students will demonstrate knowledge of and skill sociocultural, historical, and philosophical perspectives on kinesiology. 4. Students will understand how motor
Structural Composites with Tuned EM Chirality.
National Technical Information Service (NTIS)
We have developed and implemented methods to predict the overall EM properties tensors including the coupling tensors based on the geometry and microstructure of an array of scattering elements, and fabricated and measured both the HM and mechanical prope...
S. Nemat-Nasser
Sincronizao em Sistemas Distribudos problemas clssicos
problema de coordena├¦├Żo distribu├Łda #12;ordena├¦├Żo de mensagens ┬Ę implementa├¦├Żo ┬Ł uso de uma fila de holdback em camada de comunica├¦├Żo chegada de mensagens processamento (aplica├¦├Żo) fila entrega fila holdback destinat├Īrio responde com uma proposta de n├║mero de ordem ┬Ł e deixa (msg, id_├║nico, num_ordem_proposto) em fila
Rodriguez, Noemi
Condiń§es fĒsicas em galßxias HII
Galßxias HII sŃo galßxias anŃs de baixa luminosidade que apresentam alta taxa de formańŃo estelar. Seus espectros sŃo dominados por intensas linhas de emissŃo devido Ó fotoionizańŃo pela presenńa de um grande n·mero de estrelas do tipo O e B. N¾s apresentamos um catßlogo espectrofotomķtrico de 111 galßxias HII observadas no telesc¾pio 1.52m do ESO com o espectr¾grafo Boller & Chivens. Determinamos propriedades estatĒsticas da amostra e derivamos condiń§es fĒsicas (temperatura eletr¶nica, densidade eletr¶nica) e abundŌncias quĒmicas. Para algumas galßxias, fomos tambķm capazes de resolver espacialmente regi§es de formańŃo estelar individuais e determinar propriedades espectrosc¾picas para estas regi§es separadamente, o que nos permitiu avaliar as flutuań§es das condiń§es fĒsico-quĒmicas dentro das galßxias HII. Em particular, vimos que apesar das galßxias HII apresentarem formańŃo estelar espalhada ao longo do corpo da galßxia, sŃo objetos quimicamente homogĻneos. A fim de estudar a evoluńŃo temporal dos objetos durante o tempo de vida das estrelas ionizantes construimos tambķm alguns diagramas relacionando raz§es de linhas de emissŃo com a largura equivalente de Hb (EW(Hb)). Para interpretar tais diagramas utilizamos modelos de fotoionizańŃo para populań§es estelares integradas. ConcluĒmos que as galßxias HII nŃo correspondem a simples idķia de um burst instantŌneo envolvido por um gßs opaco aos f¾tons ionizantes e com densidade constante. As relań§es observadas entre raz§es de linhas e EW(Hb) podem ser melhor compreendidas se as galßxias HII apresentarem populań§es estelares mais velhas, que contribuem para o contĒnuo ¾ptico observado.
Kehrig, C.; Telles, E.; Cuisinier, F.
DIVIS├O DE TRABALHO E RELAŪAO DE G╩NERO EM COMUNIDADES AMAZįNICAS: UMA REALIDADE EM TRANSFORMAŪ├O
As relań§es de gĻnero constituem o conjunto das relań§es sociais e econ¶micas no universo do trabalho, da cultura e da polĒtica. Estß organizada a partir dos papķis masculinos e femininos dentro de estruturas que permanecem constantes em algumas sociedades ou de forma presente no inconsciente social que Ós vezes ķ refletido em ań§es do cotidiano colocando cada agente social dentro
Albejamere Pereira de Castro
SOFIS FTS EM test results
The Solar Occultation FTS for Inclined-orbit Satellite (SOFIS) is a solar occultation Fourier transform spectrometer developed by the Ministry of the Environment (MOE) in Japan for the Global Change Observation Mission-A1 (GCOM-A1) satellite. GCOM-A1 will be placed in a 650 km non-sun-synchronous orbit, with an inclination angle of 69 degrees. ABB-Bomem is a sub-contractor of NTSpace (NEC-Toshiba Space) for the design and manufacturing of the FTS Engineering Model of SOFIS. SOFIS measures the vertical profile of the atmospheric constituents with 0.2 cm-1 spectral resolution for the spectral range covering 3-13 ?m. The atmospheric vertical resolution of SOFIS is 1 km. The target of SOFIS measurements is a global distribution of O3, HNO3, NO2, N2O, CH4, H2O, CO2, CFC-11, CFC-12, ClONO2, aerosol extinction, atmospheric pressure and temperature. NTSpace in Japan is the prime contractor of SOFIS. The spectrometer is an adapted version of the classical Michelson interferometer using an optimized optical layout and moving retro-reflectors. A solid-state laser diode operating at 1550 nm is used as metrology source of the interferometer. Its highly folded optical design results in a high performance instrument with a compact size. SOFIS FTS implements high performance control techniques to achieve outstanding speed stability of the moving mechanism. This paper describes the test activities of the SOFIS-FTS Engineering Model (EM) and preliminary results. The performances of the FTS are presented in terms of key parameters like signal-to-noise ratio, modulation efficiency and stability. Spectra acquired are shown and test methodology and analyses are presented. Lessons learned during assembly, integration and testing are described as well as improvements planned to be implemented in the Flight Model.
Soucy, Marc-Andre A.; Levesque, Luc E.; Tanii, Jun; Kawashima, Takahiro; Nakajima, Hideaki
Tour of the Electromagnetic Spectrum (EMS) Videos
These videos introduce middle- and high school-age learners to the electromagnetic spectrum. The product consists of 8 animations including an introduction to electromagnetic waves and one animation for each wavelength of the EM spectrum (Radio, Microwave, Infrared, Visible, Ultraviolet, X-Rays and Gamma Rays). Each wavelength of the EM spectrum offers a construct to illustrate and teach about NASA sensors, missions, and science. Emphasis is placed on relevant science, such as lunar exploration, and hot science topics, such as climate change. The examples and narrative for each wavelength animation build on the learnersŌ prior knowledge then introduces examples from NASA missions. These examples explore the use of spectral analysis and visualizations that help scientists make discoveries about the world around us using EM waves.
Benesch, Troy
Risk Communication Within the EM Program
The U.S. Department of Energy Environmental Management program (EM) conducts the most extensive environmental remediation effort in the world. The annual EM budgets have exceeded $6,000,000,000 for approximately ten years and EM has assumed responsibility for the cleanup of the largest DOE reservations (i.e., at Hanford, Washington, Aiken, South Carolina, and Idaho Falls, Idaho) as well as the facilities at Rocky Flats, Colorado and in Ohio. Each of these sites has areas of extensive radioactive and chemical contamination, numerous surplus facilities that require decontamination and removal, while some have special nuclear material that requires secure storage. The EM program has been criticized for being ineffective (1) and has been repeatedly reorganized to address perceived shortcomings. The most recent reorganization was announced in 2001 to become effective at the beginning of the 2003 Federal Fiscal Year (i.e., October 2002). It was preceded by a ''top to bottom'' review (TTBR) of the program (2) that identified several deficiencies that were to be corrected as a result of the reorganization. One prominent outcome of the TTBR was the identification of ''risk reduction'' as an organizing principle to prioritize the activities of the new EM program. The new program also sought to accelerate progress by identifying a set of critical activities at each site that could be accelerated and result in more rapid site closure, with attendant risk, cost, and schedule benefits. This paper investigates how the new emphasis on risk reduction in the EM program has been communicated to EM stakeholders and regulators. It focuses on the Rocky Flats Environmental Technology Site (RFETS) as a case study and finds that there is little evidence for a new emphasis on risk reduction in EM communications with RFETS stakeholders. Discussions between DOE and RFETS stakeholders often refer to ''risk,'' but the word serves as a placeholder for other concepts. Thus ''risk'' communication at RFETS is lively and involves important issues, but often does not inform participants about true ''risk reduction.''
Edelson, M.
7 CFR 1945.35 - Special EM loan training.
...2012-01-01 false Special EM loan training. 1945.35 Section 1945.35 Agriculture Regulations of the Department...CONTINUED) EMERGENCY Disaster Assistance-General ¦ 1945.35 Special EM loan training. (a)...
Code of Federal Regulations, 2010 CFR
...2009-01-01 true Special EM loan training. 1945.35 Section 1945.35 Agriculture Regulations of the Department...CONTINUED) EMERGENCY Disaster Assistance-General ¦ 1945.35 Special EM loan training. (a)...
Code of Federal Regulations, 2011 CFR
EM-ONE : an architecture for reflective commonsense thinking
This thesis describes EM-ONE, an architecture for commonsense thinking capable of reflective reasoning about situations involving physical, social, and mental dimensions. EM-ONE uses as its knowledge base a library of ...
Singh, Pushpinder, 1972-2006.
1 UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 04/2011 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA PARA O CURSO DE MESTRADO PROFISSIONAL EM ECONOMIA ┬Ł AREA DE CONCENTRA├?├?O EM GEST├?O ECON├?MICA DE FINAN├?AS P├?BLICAS PARA O SEGUNDO PER├ŹODO LETIVO DE
Lucero, Jorge Carlos
1 UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 4/2013 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA PARA O CURSO DE MESTRADO PROFISSIONAL EM ECONOMIA ┬Ł AREA DE CONCENTRA├?├?O EM GEST├?O ECON├?MICA DE FINAN├?AS P├?BLICAS PARA O SEGUNDO PER├ŹODO LETIVO DE
1 UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 5/2013 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA PARA O CURSO DE MESTRADO PROFISSIONAL EM ECONOMIA ┬Ł AREA DE CONCENTRA├?├?O EM GEST├?O ECON├?MICA DE FINAN├?AS P├?BLICAS PARA O SEGUNDO PER├ŹODO LETIVO DE
Marvin, rob¶ construtor para competińŃo em rob¾tica m¾vel
renatohsp@gmail .com Resumo: Este artigo ķ sobre a construńŃo do rob¶ aut¶nomo Marvin o Construtor, que foi construĒdo para participar da IV CompetińŃo IEEE Brasileira de Rob¶. A tarefa consiste em empilhar blocos em uma ßrea predeterminada em um menor tempo possĒvel, ganha a torre mais alta. O rob¶, construĒdo por alunos do Instituto Tecnol¾gico de Aeronßutica (ITA), foi construĒdo
Andrķ Martin Narciso; Carlos Augusto; Bentes da Silva; Jackson Paul Matsuura
On Convergence Properties of the EM Algorithm for Gaussian Mixtures
We build up the mathematical connection between the Expectation-Maximization (EM) algorithm and gradient-based approaches for maximum likelihood learning of finite gaussian mixtures. We show that the EM step in parameter space is obtained from the gradient via a projection matrix P, and we provide an explicit expression for the matrix. We then analyze the convergence of EM in terms of
Lei Xu; Michael I. Jordan
CURSO DE P├?S-GRADUA├?├?O EM METEOROLOGIA Coordenadora Acad├¬mica Maria Paulete Pereira Martins Membros Bueno Pereira, Ph.D., W.M.Rice University, 1980 Gilberto Fernando Fisch, Doutor, INPE, 1995 Iracema, INPE, 2002 Maria Paulete Pereira Martins, Doutora, INPE, 1996 Marley Cavalcante de Lima Moscati
CURSO DE P├?S-GRADUA├?├?O EM METEOROLOGIA Coordenadora Acad├¬mica Maria Paulete Pereira Martins Bueno Pereira, Ph.D., W.M.Rice University, 1980 Gilberto Fernando Fisch, Doutor, INPE, 1995 Iracema, INPE, 2002 Maria Paulete Pereira Martins, Doutora, INPE, 1996 Marley Cavalcante de Lima Moscati
CURSO DE P├?S-GRADUA├?├?O EM METEOROLOGIA Coordenadora Acad├¬mica Maria Paulete Pereira Martins-USP, 2002 ├?nio Bueno Pereira, Ph.D., W.M.Rice University, 1980 Gilberto Fernando Fisch, Doutor, INPE, 1995, INPE, 2002 Maria Paulete Pereira Martins, Doutora, INPE, 1996 Marley Cavalcante de Lima Moscati
GEOBULLETIN NOvEmBEr 8Th
GEOBULLETIN NOvEmBEr 8Th 2013 - 1 - GeoBulletin is distributed weekly, by E-mail. Contributions are requested! If you have a news item, a request, an announcement etc. email it to email@example.com or leave it at the office, Room 225 by Noon on Wednesday. WEEKS LECTURE - FALL 2013 Nov. 8 Graham Kent
Carlson, Anders
EMS response to an airliner crash.
This report of an aircraft crash at a major airport in Kingston, Jamaica examines the response of the local Emergency Medical Services (EMS). Factors that impacted the response are discussed, and the need for more disaster simulation exercises is highlighted. The objective of this case report was to document the response of EMS personnel to the crash of American Airlines Flight 331, and to utilize the information to examine and improve the present protocol. While multiple errors can occur during a mass-casualty event, these can be reduced by frequent simulation exercises during which various personnel practice and learn designated roles. Efficient triage, proper communication, and knowledge of the roles are important in ensuring the best possible outcome. While the triage system and response of the EMS personnel were effective for this magnitude of catastrophe, more work is needed in order to meet predetermined standards. Ways in which this can be overcome include: (1) hosting more disaster simulation exercises; (2) encouraging more involvement with first responders; and (3) strengthening the links in the local EMS system. Vigorous public education must be instituted and maintained. PMID:22853919
Dasgupta, Shuvra; French, Simone; Williams-Johnson, Jean; Hutson, Rhonda; Hart, Nicole; Wong, Mark; Williams, Eric; Espinosa, Kurdell; Maycock, Celeste; Edwards, Romayne; McCartney, Trevor; Cawich, Shamir; Crandon, Ivor
de Ps-Graduao em Enfermagem
CAPES/PNPD A Profa. Dra Marta Lenise do Prado, docente do Programa de P├│s-gradua├¦├Żo em Enfermagem da (via e-mail), para agendar uma entrevista para argui├¦├Żo do curr├Łculo, considerando o perfil adequado ao
Floeter, Sergio Ricardo
CNMP, CSP, EMS and Writing It Down
by farmers, leading to... ┬Ę Increasing importance of "writing it down" #12;Examples.. ┬Ę NMP, CNMP ┬Ę PMPOp & plan for more ┬Ę III - meet all natural resource concerns #12;NMP & CNMP ┬Ę NMP in WI rules; CNMP and erosion #12;EMS is HQ ┬Ę CSP, NMP, PMP, CNMP alphabet soup ┬Ę Are components of an Environmental Management
Balser, Teri C.
GEOBULLETIN NOvEmBEr 15Th
to hydrothermal convection of groundwater connected to surface water Thermal springs are ubiquitous features whose;GEOBULLETIN NOvEmBEr 15Th 2013 - 2 - hydrothermal convection cells circulating groundwater within the near hydrothermal circulation of groundwater. For example, these requirements are met in many areas within
Regional EM studies in the 80's
The review describes in broad terms the development of regional EM studies during the last five-six years. Large simultaneous magnetometer arrays, broadband and dense profiling with five component instruments, the use of remote reference techniques and in-field data processing have increased both the number and the quality of EM surveys. The increase has been strong all over the world. An extensive list of references, divided geographically, is presented. Selected examples of regional resisitivity-versus-depth curves are shown for Africa, the Baikal region, the Baltic Shield, the Canadian Shield, the Carpathian regions, the Central Andes, Iceland, India, the Juan de Fuca Plate, the M³nsterland Basin, the Rio Grande rift, the Scottish Caledonides, the Tasman Sea, and for the United States in general. Because of the influence of tectonic settings and the metamorphic grade of rocks, only qualitative aspects of the results are relevant. æClassicalÆ array studies, especially in Australia, in the Carpathian regions, in India, in North Germany and in Scotland have been reinterpreted and completed with more accurate 2D modelling and dense MT profiling. In the USA and Canada also new regions have been surveyed extensively. New regional EM work has been conducted extensively on the Baltic Shield and in Central and North Africa, Siberia, China, in the areas around the Caspian and Black Seas and in South America. The newest studies are supported by or compared with other geophysical data, which also are used in extrapolating for missing EM data density. There are several successful large-scale projects in operation: the European Geotraverse (EGT), the KAPG International Geotraverses and the EMSLAB project (with its first preliminary results). Regional EM studies have been increasingly applied to geothermal, hydrocarbon and mineral prospecting as well as local structural studies, e.g. studies of sites for nuclear waste disposal.
Hjelt, S. E.
Modelling and design for PM/EM magnetic bearings
A mathematical model of a permanent magnet/electromagnet (PM/EM) radially active bearing is presented. The bearing is represented by both a reluctance model and a stiffness model. The reluctance model analyzes the magnetic circuit of the PM/EM bearings. By combining the two models, the performance of the bearing can be predicted given geometric dimensions, permanent magnet strength, and the parameters of the EM coils. The overall bearing design including the PM and EM design is subject to the performance requirement and physical constraints. A study of these requirements and constraints is discussed. The PM design is based on the required magnetic flux for proper geometric dimensions and magnet strength. The EM design is based on the stability and force slew rate consideration, and dictates the number of turns for the EM coils and the voltage and current of the power amplifier. An overall PM/EM bearing design methodology is proposed and a case study is also demonstrated.
Pang, D.; Kirk, J. A.; Anand, D. K.; Johnson, R. G.; Zmood, R. B.
The association between EMS workplace safety culture and safety outcomes
Objective Prior studies have highlighted wide variation in EMS workplace safety culture across agencies. We sought to determine the association between EMS workplace safety culture scores and patient or provider safety outcomes. Methods We administered a cross-sectional survey to EMS workers affiliated with a convenience sample of agencies. We recruited these agencies from a national EMS management organization. We used the EMS Safety Attitudes Questionnaire (EMS-SAQ) to measure workplace safety culture and the EMS Safety Inventory (EMS-SI), a tool developed to capture self-reported safety outcomes from EMS workers. The EMS-SAQ provides reliable and valid measures of six domains: safety climate, teamwork climate, perceptions of management, perceptions of working conditions, stress recognition, and job satisfaction. A panel of medical directors, paramedics, and occupational epidemiologists developed the EMS-SI to measure self-reported injury, medical errors and adverse events, and safety-compromising behaviors. We used hierarchical linear models to evaluate the association between EMS-SAQ scores and EMS-SI safety outcome measures. Results Sixteen percent of all respondents reported experiencing an injury in the past 3 months, four of every 10 respondents reported an error or adverse event (AE), and 90% reported safety-compromising behaviors. Respondents reporting injury scored lower on 5 of the 6 domains of safety culture. Respondents reporting an error or AE scored lower for 4 of the 6 domains, while respondents reporting safety-compromising behavior had lower safety culture scores for 5 of 6 domains. Conclusions Individual EMS worker perceptions of workplace safety culture are associated with composite measures of patient and provider safety outcomes. This study is preliminary evidence of the association between safety culture and patient or provider safety outcomes. PMID:21950463
Weaver, Matthew D.; Wang, Henry E.; Fairbanks, Rollin J.; Patterson, Daniel
PERFIL EPIDEMIOLėGICO DO TRAUMA DE FACE DOS PACIENTES ATENDIDOS NO PRONTO SOCORRO DE UM HOSPITAL P┌BLICO EPIDEMIOLOGY OF FACIAL TRAUMA OF PATIENTS ADMITTED TO A PUBLIC HOSPITAL EMERGENCY DEPARTMENT
RESUMO: Objetivo: Avaliar os dados epidemiol¾gicos e a localizańŃo dos traumas de face de pacientes atendidos no Hospital Regional da Asa Norte (HRAN), BrasĒlia, Distrito Federal. Mķtodo: Trata-se de um estudo retrospectivo, realizado no pronto socorro do HRAN- DF, visando avaliar o perfil epidemiol¾gico dos pacientes atendidos pela equipe da Unidade de Cirur gia Plßstica vĒtimas de trauma de face
Jefferson Lessa; Soares de Macedo; Larissa Macedo de Camargo; Pedro Fragoso de Almeida; Simone CorrĻa Rosa
Crosshole EM in steel-cased boreholes
The application of crosshole EM methods through steel well-casing was investigated in theoretical, laboratory and field studies. A numerical code was developed that calculates the attenuation and phase delay of an EM dipole signal propagated through a steel well casing lodged in a homogeneous medium. The code was validated with a scale model and used for sensitivity studies of casing and formation properties. Finally, field measurements were made in an oil field undergoing waterflooding. Our most important findings are that (1) crosshole surveys are feasible using a well pair with one metallic and one non-metallic casing. (2) The casing effect seems be localized within the pipe section that includes the sensor. (3) The effects of the casing can be corrected using simple means and (4) crosshole field data that are sensitive to both formation and casing were acquired in a working environment.
Wilt, M.; Lee, K.H.; Becker, A.; Spies, B.; Wang, B.
Helicopter EMS: Research Endpoints and Potential Benefits
Patients, EMS systems, and healthcare regions benefit from Helicopter EMS (HEMS) utilization. This article discusses these benefits in terms of specific endpoints utilized in research projects. The endpoint of interest, be it primary, secondary, or surrogate, is important to understand in the deployment of HEMS resources or in planning further HEMS outcomes research. The most important outcomes are those which show potential benefits to the patients, such as functional survival, pain relief, and earlier ALS care. Case reports are also important ōoutcomesö publications. The benefits of HEMS in the rural setting is the ability to provide timely access to Level I or Level II trauma centers and in nontrauma, interfacility transport of cardiac, stroke, and even sepsis patients. Many HEMS crews have pharmacologic and procedural capabilities that bring a different level of care to a trauma scene or small referring hospital, especially in the rural setting. Regional healthcare and EMS system's benefit from HEMS by their capability to extend the advanced level of care throughout a region, provide a ōbackupö for areas with limited ALS coverage, minimize transport times, make available direct transport to specialized centers, and offer flexibility of transport in overloaded hospital systems. PMID:22203905
Thomas, Stephen H.; Arthur, Annette O.
Planificaci¾n de la transici¾n a la atenci¾n en la etapa final de la vida para los pacientes de cßncer en estadio avanzado (PDQ«)
Resumen de informaci¾n revisada por expertos sobre la preparaci¾n necesaria por parte de los proveedores de atenci¾n de la salud, los pacientes y sus familas para la transici¾n a la etapa final de la vida en los casos de cßncer en estadio avanzado.
Los NIH anuncian el lanzamiento de 3 estudios integrados de medicina de precisi¾n; ALCHEMIST es para pacientes con ciertos tipos de cßncer de pulm¾n en estadio inicial
Los Estudios sobre la Secuenciaci¾n e Identificaci¾n de Marcadores para el Mejoramiento de la Terapia Adjuvante para el Cßncer de Pulm¾n, conocidos con el nombre de ALCHEMIST, identificarßn a pacientes con cßncer de pulm¾n en estadio inicial cuyos tumores albergan ciertos cambios genķticos, y evaluarßn si los tratamientos con medicamentos que act·an sobre esos cambios pueden mejorar la supervivencia.
Planificaci¾n de la transici¾n a la atenci¾n en la etapa final de la vida para los pacientes con cßncer en estadio avanzado (PDQ«)
Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol
995 Summary Background Blood pressure reduction achieved with ? -blockers and diuretics is the best recorded intervention to date for prevention of cardiovascular morbidity and death in patients with hypertension. Left ventricular hypertrophy (LVH) is a strong independent indicator of risk of cardiovascular morbidity and death. We aimed to establish whether selective blocking of angiotensin II improves LVH beyond reducing
Bj÷rn Dahl÷f; Richard B Devereux; Sverre E Kjeldsen; Stevo Julius; Gareth Beevers; Ulf de Faire; Frej Fyhrquist; Hans Ibsen; Krister Kristiansson; Ole Lederballe-Pedersen; Lars H Lindholm; Markku S Nieminen; Per Omvik; Suzanne Oparil; Hans Wedel
Sequence analysis of two tandemly linked Em genes from wheat
DNA sequences are presented for two members of the wheat Em gene family. The sequences correspond to the two linked genes at the Xem-1AL locus. Comparisons of these sequences with that of another wheat Em gene and two Em cDNA clones reveals substantial homology within the protein-coding regions, and the presence in the 5'-flanking regions of the genomic sequences of
T. Simon Futers; Sertac Onde; Muge Turet; Andrew C. Cuming
UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 03/2012 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S- GRADUA├?├?O EM ECONOMIA PARA O CURSO DE DOUTORADO ACAD├?MICO PARA O PRIMEIRO SEMESTRE LETIVO DE 2013 A Coordena├¦├Żo do Programa de P├│s-Gradua├¦├Żo em Economia da Universidade de
1/4 UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 02/2011 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA PARA O CURSO DE DOUTORADO PARA O PRIMEIRO PER├ŹODO LETIVO DE 2012 1. PRE├?MBULO 1.1. O Coordenador do Programa de P├│s-Gradua├¦├Żo em Economia, no uso de
UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 03/2013 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S- GRADUA├?├?O EM ECONOMIA PARA O CURSO DE DOUTORADO ACAD├?MICO PARA O PRIMEIRO SEMESTRE LETIVO DE 2014 PRE├?MBULO O Coordenador do Programa de P├│s-Gradua├¦├Żo em Economia da
UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 04/2011 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S- GRADUA├?├?O EM ECONOMIA PARA O CURSO DE DOUTORADO ACAD├?MICO PARA O PRIMEIRO SEMESTRE LETIVO DE 2012 A Coordena├¦├Żo do Programa de P├│s-Gradua├¦├Żo em Economia da Universidade de
1/4 UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 02/2010 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA PARA O CURSO DE DOUTORADO PARA O PRIMEIRO PER├ŹODO LETIVO DE 2011 1. PRE├?MBULO 1.1. O Coordenador do Programa de P├│s-Gradua├¦├Żo em Economia, no uso de
1/3 UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 01/2011 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA PARA O CURSO DE MESTRADO ACAD├?MICO PARA O PRIMEIRO PER├ŹODO LETIVO DE 2012 1. PRE├?MBULO 1.1. O Coordenador do Programa de P├│s-Gradua├¦├Żo em Economia
Photon kinetic description of 1D relativistic EM pulse solitons
Photon kinetics provides a novel formalism to describe intense EM fields-plasma interactions, where the EM fields are described as a collection of quasi-particles (photons). Photon kinetics provides a better physical picture of the EM fields dynamics, is computionally less demanding, and allows for an easy description of broadband incoherent light pulses. We have developed a 1D photon kinetic code, where
R. Trines; R. Bingham; W. B. Mori; L. O. Silva
Propriedades termodinŌmicas de um gßs ideal em superfĒcies hiperb¾licas compactas.
??Neste trabalho investigamos algumas propriedades termodinŌmicas de gases ideais em superfĒcies compactas de curvatura constante e negativa. Super- fĒcies com propriedades similares aparecem, por exemplo,ģ (more)
Diego de Fl¶or e Silva
Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey
2. HI PAR (ACQUISITION RADAR) TOWER AND ENLISTED MEN (EM) BARRACKS WITH RADAR ATTACHED. - Nike Hercules Missile Battery Summit Site, Battery Control Administration & Barracks Building, Anchorage, Anchorage, AK
BUSCA LOCAL PARA P┬┤OS-PROCESSAMENTO EM RESULTADOS DE OTIMIZA┬ĖC~AO MULTI-OBJETIVO EM REDES DE FILAS otimiza┬Ėc~ao de redes de filas finitas, a capacidade total do sistema em ┬┤areas de espera deve ser a menor redistribui┬Ėc~ao de ┬┤areas de circula┬Ėc~ao entre as filas, preservando fixa a capacidade total do sistema. Um
Cruz, Frederico
HISTėRIA, LITERATURA E DITADURA: O CASO JO├O PAZ EM INCIDENTE EM ANTARES
This article refers to a possible critic of the Brazilian military and dictatorial regime in the 1960┤s and 1970s, trough the eyes of JoŃo Paz, a character in the novel of Erico VerĒssimo, Incidente em Antares . The research, from a bibliographic point of view, has been based on recent theories that relate to facts in the History and Literature
Daniela Freitas Torres; Elaine dos Santos
BENJAMIN FRANKLIN E A HISTėRIA DA ELETRICIDADE EM LIVROS DID┴TICOS
IntroduńŃo Nos ·ltimos anos, a hist¾ria da ciĻncia vem sendo introduzida em materiais didßticos utilizados em sala de aula. Uma das raz§es para isso ķ a pressŃo de ¾rgŃos governamentais, tais como a Secretaria de EducańŃo Bßsica, responsßvel pela avaliańŃo destes livros dentro do Programa Nacional de Livros Didßticos para o ens ino fundamental e mķdio. Os editais destes programas
Cibelle Celestino Silva; Ana Carolina Pimentel
Processamento auditivo e SPECT em crianńas com dislexia
RESUMO - Aplicamos em um grupo de 36 crianńas os testes dic¾tico de dĒgitos, dic¾tico de dissĒlabos altern a- dos e dic¾tico nŃo-verbal, os quais fazem parte do conjunto de avaliańŃo do processamento auditivo. As crianńas foram divididas em dois grupos que foram correlacionados: grupo experimental (GE) formado por 18 crianńas com diagn¾stico de dislexia e 18 crianńas normais compondo
Luciane Sauer; Liliane Desgualdo Pereira; Sylvia Maria Ciasca; Magda Pestun; Marilisa M. Guerreiro
10 CFR Appendixes E-M to Part 52 - [Reserved
10 Energy 2 2014-01-01 2014-01-01 false [Reserved] E Appendixes E-M to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Appendixes E-M to Part 52...
Standard Errors for EM Estimates in Generalized Linear Models with
. As additional covariate among others the temperature was recorded. The bacteria content was determinedStandard Errors for EM Estimates in Generalized Linear Models with Random Effects Herwig Friedl of EM estimates in generalized linear models with random effects. Quadrature formulae are used
Friedl, Herwig
Stochastic EM-based TFBS motif discovery with MITSU
Motivation: The Expectation¢Maximization (EM) algorithm has been successfully applied to the problem of transcription factor binding site (TFBS) motif discovery and underlies the most widely used motif discovery algorithms. In the wider field of probabilistic modelling, the stochastic EM (sEM) algorithm has been used to overcome some of the limitations of the EM algorithm; however, the application of sEM to motif discovery has not been fully explored. Results: We present MITSU (Motif discovery by ITerative Sampling and Updating), a novel algorithm for motif discovery, which combines sEM with an improved approximation to the likelihood function, which is unconstrained with regard to the distribution of motif occurrences within the input dataset. The algorithm is evaluated quantitatively on realistic synthetic data and several collections of characterized prokaryotic TFBS motifs and shown to outperform EM and an alternative sEM-based algorithm, particularly in terms of site-level positive predictive value. Availability and implementation: Java executable available for download at http://www.sourceforge.net/p/mitsu-motif/, supported on Linux/OS X. Contact: email@example.com PMID:24931999
Kilpatrick, Alastair M.; Ward, Bruce; Aitken, Stuart
Under Review Scaling Down EM Using Graph Based
a probabilistic model formulation characterized by the parameters of the probability distribution. For example, in the above applications [3, 17] a #12;Scaling Down EM Using Graph Based Models 3 Gaussian distributionUnder Review Scaling Down EM Using Graph Based Models Ian Davidson Department of Computer Science
Davidson, Ian
A Double Layer Electromagnetic Cloak And GL EM Modeling
In this paper, we propose a novel electromagnetic (EM) cloaking structure that consists of two annular layers between three spherical shells and model its performance numerically and theoretically by using a Global and Local EM field (GL) method. The two annular layers contain distinct cloaking materials: the outer layer provides invisibility; the inner layer is fully absorbing. The cloaking materials are weakly degenerative. The wavefield from an EM source located outside the cloak propagates as in free space outside the outer shell, never be disturbed by the cloak and does not penetrate into the inner absorbing layer and concealment. The field of a source located inside inner layer or the cloaked concealment is completely absorbed by the inner layer and never reaches the outside of the middle shell, Moreover, the EM wavefield excited in concealment is not disrupted by the cloak. There exists no Maxwell EM wavefield can be excited in a single layer cloaked concealment which is filled by normal material. More...
Xie, Ganquan; Xie, Feng; Xie, Lee
Estudo sobre qualidade de vida com pacientes p¾s-TMO: aplicańŃo do questionßrio WHOQOL-Bref Study on quality of life of post-BMT patients: application of WHOQOL-Bref questionnaire Estudio de la calidad de vida de pacientes de post-TMO: aplicaci¾n del cuestionario WHOQOL-Bref
RESuMO: O presente trabalho teve por objetivo avaliar a qualidade de vida de pacientes submetidos ao transplante de medula ¾ssea utilizando-se um questionßrio de avaliańŃo de qualidade de vida, e refletir sobre as contribuiń§es deste instrumento para a compreensŃo do impacto da doenńa na vida destes sujeitos, bem como a utilidade destes indicadores para formular e fundamentar o raciocĒnio clĒnico
Maria da ConceińŃo dos Santos; Fernanda de Castro Ferreira; Silva Moreira; Marina Ribeiro Rodrigues
Electromagnetic optimization of EMS-MAGLEV systems
In EMS-MAGLEV high-speed transport systems, devices for propulsion, levitation and contactless on-board electric power transfer are combined in a single electromagnetic structure. The strong coupling among the windings affects the performance of each device and requires the utilization of numerical codes. The paper describes an overall optimization procedure, based on a suitable mathematical model of the system, which takes into account several items of the system performance. The parameters of the model are calculated by an automated sequence of FEM analyses of the configuration. Both the linear generator output characteristics and the propulsion force ripple are improved applying the procedure to a reference configuration. The results are compared with the results obtained by a sequence of partial optimizations operating separately on two different subsets of the geometric parameters.
Andriollo, M.; Martinelli, G.; Morini, A.; Tortella, A. [Univ. of Padova (Italy). Dept. of Electrical Engineering] [Univ. of Padova (Italy). Dept. of Electrical Engineering
DOE EM industry programs robotics development
The Office of Science and Technology (OST) manages an aggressive program for RD&D, as well as testing and evaluation for the U.S. Department of Energy`s (DOE) Environmental Management (EM) organization. The goal is to develop new and improved environmental restoration and waste management technologies to clean up the inventory of the DOE weapons complex faster, safer, and cheaper than is possible with currently available technologies. OST has organized technology management activities along focus teams for each major problem area. There are currently five focus areas: decontamination and decommissioning, tanks, subsurface contaminants, mixed waste, and plutonium. In addition, OST is pursuing research and development (R&D) that cuts across these focus areas by having applications in two or more focus areas. Currently, there are three cross-cutting programs: the robotics technology development; characterization, monitoring, and sensor technologies; and efficient separations and processing.
Staubly, R.; Kothari, V. [Dept. of Energy, Morgantown, WV (United States)
Evaluation of Fracture Azimuth by EM Wave and Elastic Wave
Fracture system plays an important role in the development of underground energy, for example enhanced geothermal system (EGS), oil shale and shale gas, etc. Therefore, it becomes more and more important to detect and evaluate the fracture system. Geophysical prospecting is an useful method to evaluate the characteristics of the subsurface fractures. Currently, micro-seismology, multi-wave seismic exploration, and electromagnetic (EM) survey are reported to be used for the purpose. We are studying a method using both elastic wave and EM wave to detect and evaluate the fracture azimuth in laboratory. First, we build a 3D horizontal transverse isotropy (HTI) model, shown in the figure 1, by dry parallel fractures system, which was constructed by plexiglass plates and papers. Then, we used the ultrasonic system to obtain reflected S-wave data. Depending on the shear wave splitting, we evaluated the fracture azimuth by the algorithm of Pearson correlation coefficient. In addition, we used the full Polarimetric ultra wide band electromagnetic (FP-UWB-EM) wave System, shown in the figure 2, to obtain full polarimetric reflected EM-wave data. Depending on the rotation of the EM wave polarimetry, we evaluated the fracture azimuth by the the ration between maximum amplitude of co-polarimetric EM wave and maximum amplitude of cross-polarimetric EM wave. Finally, we used both EM-wave data and S-wave data to evaluate the fracture azimuth by the method of cross plot and statistical mathematics. To sum up, we found that FP-UWB-EM wave can be used to evaluated the fracture azimuth and is more accurate than ultrasound wave. Also joint evaluation using both data could improve the precision.
Feng, X.; Wang, Q.; Liu, C.; Lu, Q.; Zeng, Z.; Liang, W.; Yu, Y.; Ren, Q.
Cultivo hidrop¶nico de lisianto p ara flor de corte em sistema de fluxo laminar de nutrientes
Resumo - O objetivo deste trabalho foi avaliar as caracterĒsticas produtivas e comerciais do cultivo de quatro cultivares de lisianto (Eustoma grandiflorum) em trĻs soluń§es nutritivas em sistema de fluxo laminar de nutrientes (NFT). Utilizou-se o delineamento em blocos casualizados, em esquema fatorial 4x3, com trĻs repetiń§es. Os tratamentos foram compostos de quatro cultivares (Echo Champagne, Mariachi Pure White, Balboa
Alice Antonello; Londero Backes; Josķ Geraldo Barbosa; Paulo Roberto Cecon; Josķ Antonio Saraiva Grossi; Rogķrio Luiz Backes; Fernando Luiz Finger; Av. P. H. Rolfs
Autonomia e MotivańŃo em narrativas de aprendizes de portuguĻs como lĒngua estrangeira1
Neste artigo, discuto os resultados de minha pesquisa dentro do projeto AMFALE - Autonomia em um Modelo Fractal de AquisińŃo de LĒngua Estrangeira. Com base em conceitos de autonomia e motivańŃo e na correlańŃo entre eles, analiso narrativas de aprendizes de portuguĻs como lĒngua estrangeira em Belo Horizonte. Tais anßlises atestam que a experiĻncia de aprendizagem inserida em uma comunidade
Fernanda Sousa Carvalho
An Innovative Tool to Assist in Rural EMS Response
technologies for EMS -NextGeneration 911 -IP telephony -AACN -Mobile phones -Computer Aided Dispatch (CAD) -GPS (security & privacy) !Users must want to use it, be able to use it, like to use it !Leverage growth
Minnesota, University of
EM 9043 October 2011 Growing Farms: Successful Whole
of the Oregon State University Extension Service Small Farms Program (http://smallfarms.oregonstate.edu) #12 ................................................................5 SWOT Analysis...............................................................7 Resource InventoryEM 9043 ┬Ę October 2011 Growing Farms: Successful Whole Farm Management Planning Book Think It
Tullos, Desiree
Genķtica de populań§es e relań§es de parentesco em Ciconiiformes (Aves).
??Estudos de genķtica de populań§es e de parentesco genķtico foram desenvolvidos em colhereiro (Platalea ajaja), cabeńa-seca (Mycteria americana) e garńa-branca-grande (Ardea alba egretta), de col¶niasģ (more)
Carolina Isabel Mi±o
Structure of Matter, Forces, EM Waves, Spectroscopy, Doppler Effect
These supplemental class notes cover the basic properties of matter, the nature of forces, the electromagnetic spectrum, and how astronomers exploit the properties of the EM spectrum to deduce the physical nature of distant objects.
O'Connell, Robert
NASA EM Followup of LIGO-Virgo Candidate Events
We present a strategy for a follow-up of LIGO-Virgo candidate events using offline survey data from several NASA high-energy photon instruments aboard RXTE, Swift, and Fermi. Time and sky-location information provided by the GW trigger allows for a targeted search for prompt and afterglow EM signals. In doing so, we expect to be sensitive to signals which are too weak to be publicly reported as astrophysical EM events.
Blackburn, Lindy L.
Users of midwest EMS firm stuck without software
Four midwest energy management system (EMS) users report delays in software delivery and a failure to achieve energy savings with National Control Systems Inc. (NCS) equipment. A fifth user has already replaced an unsatisfactory NCS system. Representatives of the users relate their experiences in trying to make the EMS systems works and to acquire the necessary software beyond the original start/stop functions. Most expect to deal with larger, more established companies in the future. (DCK)
Galvin, C.
EM algorithm estimation of TCM scheme over multipath fading
estimate is available to the receiver. B. Previous Research The following are some studies in application of EM algorithm in a, communicat, ion problem. Han and Georghiades [I] investigated the application of EM algorithm to t, he optimum receiver... 4. In Sections A and C, the structure of encoder an&i decoder implemented in the simulation is described. We described how the fading model is simulated in Section B. A. Transmitter A transmitter used in this study employs Ungerboeck's 8-state...
Gunawan, Wiedy
An Effective EMS Hardware and Software Interface- The Trained Operator
you have es tablished operator training objectives, selecting appropriate training methods becomes easier. OPERATOR SKILL CATEGORIES Identifying and defining your EMS instructional objectives can be a fairly straightforward process. There is a... ings are minimal. An operator needs the full capability of being able to address all the EMS features and related individ ual building functions. Can you see the results of having a fully trained operator? Less personal frustration, improved use...
Cherry, C. L.
EM clustering analysis of diabetes patients basic diagnosis index.
Cluster analysis can group similar instances into same group and different instances into different groups. It assigns classes to samples without known the classes in advance. EM clustering algorithm can find number of distributions of generating data and build "mixture models". It identifies groups that are either overlapping or varying sizes and shapes. In this project, by using EM in Weka system, diabetes patient basic diagnosis index data have been analyzed for clustering. PMID:16779444
Wu, Cai; Steinbauer, Jeffrey R; Kuo, Grace M
Fibrose pulmonar ocupacional, cŌncer de laringe e pneumonia de repetińŃo em paciente idoso: relato de caso interdisciplinar Occupational lung fibrosis, cancer of the larynx and pneumonia of repetition in an aged patient: an interdisciplinary case study Fibrosis ocupacional del pulm¾n, cßncer de la laringe y pulmonĒa a repetici¾n en un paciente envejecido: un estudio de caso interdisciplinario
ReSumO: A fibrose pulmonar apresenta in·meras complicań§es sistĻmicas, como a desnutrińŃo e a reduńŃo da capacidade funcional. O tratamento deve ser indi- vidualizado e desenhado para minimizańŃo dos sintomas, otimizańŃo do status funcional e reduńŃo dos gastos com sa·de. Este estudo teve por objetivo avaliar o impacto da abordagem interdisciplinar na reabilitańŃo de idoso com fibrose pulmonar e desnutrińŃo. Trata-se
Dķbora Rocha Oliveira; Alexandre Luque; Maria Alice de Gouveia Pereira; Andrķa de Souza; Vera Silvia Frangella
EM Task 9 - Centrifugal Membrane Filtration
This project is designed to establish the utility of a novel centrifugal membrane filtration technology for the remediation of liquid mixed waste streams at US Department of Energy (DOE) facilities in support of the DOE Environmental Management (EM) program. The Energy and Environmental Research Center (EERC) has teamed with SpinTek Membrane Systems, Inc., a small business and owner of the novel centrifugal membrane filtration technology, to establish the applicability of the technology to DOE site remediation and the commercial viability of the technology for liquid mixed waste stream remediation. The technology is a uniquely configured process that makes use of ultrafiltration and centrifugal force to separate suspended and dissolved solids from liquid waste streams, producing a filtered water stream and a low-volume contaminated concentrate stream. This technology has the potential for effective and efficient waste volume minimization, the treatment of liquid tank wastes, the remediation of contaminated groundwater plumes, and the treatment of secondary liquid waste streams from other remediation processes, as well as the liquid waste stream generated during decontamination and decommissioning activities.
Stevens, B.G.; Stepan, D.J.; Hetland, M.D.
The Office of Science and Technology (OST) manages an aggressive program for RD and D, as well as testing and evaluation for the Department of Energy`s (DOE`s) Environmental Management (EM) organization. The goal is to develop new and improved environmental restoration and waste management technologies to clean up the inventory of the DOE weapons complex faster, safer, and cheaper than is possible with currently available technologies. Robotic systems reduce worker exposure to the absolute minimum, while providing proven, cost-effective, and, for some applications, the only acceptable technique for addressing challenging problems. Development of robotic systems for remote operations occurs in three main categories: tank waste characterization and retrieval; decontamination and dismantlement; and characterization, mapping, and inspection systems. In addition, the Federal Energy Technology Center (FETC) has some other projects which fall under the heading of supporting R and D. The central objective of all FETC robotic projects is to make robotic systems more attractive by reducing costs and health risks associated with the deployment of robotic technologies in the cleanup of the nuclear weapons complex. This will be accomplished through development of robots that are cheaper, faster, safer, and more reliable, as well as more straightforward to modify/adapt and more intuitive to operate with autonomous capabilities and intelligent controls that prevent accidents and optimize task execution.
Staubly, R.; Kothari, V.
Isolamento de Salmonella spp. em pombos (Columba livia) no Distrito Federal : aspecto de relevŌncia ao sistema de vigilŌncia em sa·de.
??DissertańŃo (mestrado)ŚUniversidade de BrasĒlia, Faculdade de Agronomia e Medicina Veterinßria, Programa de P¾s-GraduańŃo em Sa·de Animal, 2014. A domesticańŃo de pombos da espķcie Columba livia,ģ (more)
Santos, Ivanildo de Oliveira Correia
CondensańŃo de Bose-Einstein para um gßs de b¾sons nŃo interagentes em confinamentos bidimensionais em automatos celulares complexos.
??Neste trabalho estudamos as propriedades termodinŌmicas da CondensańŃo de Bose-Einstein (CBE) para um gßs de b¾sons nŃo-interagentes confinado em potenciais bidimensionais V(x,y) que apresentam classicamente,ģ (more)
Daniel Schardosim Calovi
SĒndrome de Wolff-Parkinson-White e outras Vias Acess¾rias Atrioventriculares em 1465 Pacientes Submetidos Ó AblańŃo por Radiofreq³Ļncia Wolff-Parkinson-White Syndrome and other Atrioventricular Accessory Pathways in 1,465 Patients Undergoing Radio-Frequency Ablation
Background: Several studies analyzed clinical and electrophysiological data for patients with accessory pathways, most of them not Brazilian and based on a relatively small number of patients. Objective: To describe the number and location of the accessory pathways in Brazilian patients undergoing radiofrequency ablation. Methods: A retrospective analysis was conducted of 1,465 consecutive patients with accessory pathways who u n
Iara Atiķ; Washington Maciel; Eduardo Andrķa; Nilson Ara·jo; Hecio Carvalho; LuĒs Belo; Leonardo Siqueira; Clßudio Munhoz; Rodrigo Cosenza; Fabiana Mitidieri; Lara Fonseca; Cristiane Bortoluzzo; Tarik Arcoverde; Bruno Andrķa; Jacob Atiķ
Efeitos da prßtica mental combinada Ó cinesioterapia em pacientes p¾s-acidente vascular encefßlico: uma revisŃo sistemßtica Effects of mental practice combined with kinesiotherapy in post stroke patients: a systematic review
SUMMARY Introduction. Mental practice (MP) consists of mental simulation of repetitive movements with the intention of promoting the learning of a motor ability. Objective. To investigate if MP, when combined to kine- siotherapy, is efficient in the motor deficit recovery in upper limbs of post stroke patients. Method. We realized Systematic Review throughout Data Bases PubMed\\/Medline, Cochrane Database of Systematic
Mariana Pacheco; Sergio Machado; Josķ Eduardo Lattari; Clßudio Elidio Portella; Bruna Velasques; Julio Guilherme Silva; Victor Hugo Bastos; Pedro Ribeiro
Methylene blue use in coronary artery bypass surgery: a prospective randomized study of the hemodynamic and inflammatory responses Efeito do azul de metileno na resposta inflamat¾ria e hemodinŌmica em pacientes submetidos Ó cirurgia de revascularizańŃo miocßrdica com circulańŃo extracorp¾rea
Objective: To assess the effects of methylene blue infusion on on-pump coronary artery bypass patients in relation to hemodynamic, laboratorial and systemic inflammatory response. Method: Sixty patients were randomized in two groups. Methylene blue was infused in one group. Blood samples were collected before the anesthesia and 3, 6, 24 and 48 hours after the end of the extracorporeal circulation
Josķ da Cruz VIANA; Eduardo Novaes; Mitermayer GalvŃo REIS; Sķrgio Almeida de OLIVEIRA
Resultados da cirurgia de transferĻncia do m·sculo reto anterior da coxa em pacientes com paralisia cerebral Anßlise computadorizada da marcha prķ e p¾s-operat¾ria * Results from transfer surgery of rectus anterior muscle of the thigh in cerebral palsy patients
Objective: To assess results of distal thigh rectus anterior muscle transfer in patients with spastic cerebral palsy. The surgery was indicated for improvement of knee flexion motion during the swing phase of the gait. Methods: A total of 58 patients were included in the study, comprising 31 males (53.4%), and 27 females (46.5%). A total number of 104 limbs were
Melanda AG; Godoy W; Lopes Jr AG; ALESSANDRO GIURIZATTO MELANDA; GARCIA LOPES JR
Nutritional, clinical and socioeconomic profile of patients with cystic fibrosis treated at a referral center in northeastern Brazil* Perfil nutricional, clĒnico e socioecon¶mico de pacientes com fibrose cĒstica atendidos em um centro de referĻncia no nordeste do Brasil
Objective: To describe the profile of patients with cystic fibrosis (CF). Methods: A prospective, cross-sectional study involving CF patients ? 18 years of age, evaluated between March and July of 2006 at a referral center in northeastern Brazil. Nutritional assessment was performed using Z scores for height\\/age (H\\/A), weight\\/age (W\\/A) and weight\\/height (W\\/H), as well as %weight\\/height (%W\\/H) and body
Silva Pinto; Cristiane Pereira da Silva; Murilo Carlos; Amorim de Britto
Prevalence of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis in the state of Bahia, Brazil* PrevalĻncia de aspergilose broncopulmonar alķrgica em pacientes com fibrose cĒstica na Bahia, Brasil
Objective: To determine the prevalence of allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis treated at a referral center in the state of Bahia, Brazil. Methods: A cross-sectional study, with prospective data collection, carried out at the Cystic Fibrosis Referral Center of Bahia of the Octßvio Mangabeira Specialized Hospital. We evaluated 74 patients diagnosed with cystic fibrosis, older than
Ana Clßudia; Costa Carneiro; Ant¶nio Carlos Moreira Lemos; Sķrgio Marcos Arruda; Maria Angķlica Pinheiro; Santos Santana
Original Article Chronic bacterial infection and echocardiographic parameters indicative of pulmonary hypertension in patients with cystic fibrosis* InfecńŃo bacteriana cr¶nica e indicadores ecocardiogrßficos de hipertensŃo pulmonar em pacientes com fibrose cĒstica
Objectives: To examine the relationship between chronic bacterial infection and pulmonary hypertension, using Doppler echocardiography, in patients with cystic fibrosis (CF). Methods: A prospective cross-sectional study involving CF patients (? 16 years of age) admitted to a program for adults with the disease. The study included 40 patients with a mean age of 23.7 ▒ 6.3 years. Patients were submitted
Paula Maria Eidt Rovedder; Bruna Ziegler; Lilian Rech Pasin; Ant¶nio Fernando; Furlan Pinotti; Sķrgio Saldanha; Menna Barreto; Paulo de Tarso; Roth Dalcin
Artigo Original PrevalĻncia de aspergilose broncopulmonar alķrgica em pacientes com fibrose cĒstica na Bahia, Brasil* Prevalence of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis in the state of Bahia, Brazil
Objective: To determine the prevalence of allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis treated at a referral center in the state of Bahia, Brazil. Methods: A cross-sectional study, with prospective data collection, carried out at the Cystic Fibrosis Referral Center of Bahia of the Octavio Mangabeira Specialized Hospital. We evaluated 74 patients diagnosed with cystic fibrosis, older than
Ana Clßudia Costa Carneiro; Ant¶nio Carlos Moreira Lemos; Sķrgio Marcos Arruda; Maria Angķlica Pinheiro; Santos Santana
Perfil nutricional, clĒnico e socioecon¶mico de pacientes com fibrose cĒstica atendidos em um centro de referĻncia no nordeste do Brasil* Nutritional, clinical and socioeconomic profile of patients with cystic fibrosis treated at a referral center in northeastern Brazil
Preditores da dessaturańŃo do oxigĻnio no teste da caminhada de seis minutos em pacientes com fibrose cĒstica* Predictors of oxygen desaturation during the six-minute walk test in patients with cystic fibrosis
Objective: To identify the predictive factors of oxygen desaturation during the six-minute walk test (6MWT) in patients with cystic fibrosis (CF). Methods: Prospective cross-sectional study involving clinically stable patients with CF aged ? 10 years. The patients were submitted to nutritional evaluations, oral glucose tolerance tests, pulmonary function tests, chest X-rays and 6MWTs. Results: The study included 88 patients (43
Bruna Ziegler; Claudine Lacerda Oliveira; Sandra Jungblut Schuh; Paulo de Tarso; Roth Dalcin
Artigo Original InfecńŃo bacteriana cr¶nica e indicadores ecocardiogrßficos de hipertensŃo pulmonar em pacientes com fibrose cĒstica* Chronic bacterial infection and echocardiographic parameters indicative of pulmonary hypertension in patients with cystic fibrosis
Objectives: To examine the relationship between chronic bacterial infection and pulmonary hypertension, using Doppler echocardiography, in patients with cystic fibrosis (CF). Methods: A prospective cross-sectional study involving CF patients (?16 years of age) admitted to a program for adults with the disease. The study included 40 patients with a mean age of 23.7 ▒ 6.3 years. Patients were submitted to
Comparison among pulmonary function test results, the Shwachman-Kulczycki score and the Brasfield score in patients with cystic fibrosis* ComparańŃo entre provas de funńŃo pulmonar, escore de Shwachman-Kulczycki e escore de Brasfield em pacientes com fibrose cĒstica
Objective: To study correlations among pulmonary function, chest radiology and clinical status in cystic fibrosis. Methods: A retrospective cross-sectional study was performed to evaluate chest X-rays and clinical charts of patients treated at the Hospital de ClĒnicas de Porto Alegre. Spirometry findings, Shwachman-Kulczycki (S-K) scores and Brasfield scores were analyzed. Results: The final sample consisted of 40 patients (mean age
Ivanice Duarte Freire; Fernando Ant¶nio de Abreu; Manuel ┬ngelo de Ara·jo
Estudo dos efeitos sens¾rio-motores da fisioterapia aqußtica com pacientes em estado de coma vigil Study of the effect motor-sensories of the aquatic therapy with patients in vigil coma stage
SUMMARY Purpose: The aim of this study was to evaluate the effect in the picture of the patient after Brain Injury (BI), in vigil coma stage, with the precocious intervention of the aquatic therapy. Method: The study it consists of a story of case, carried through in the Israelita Albert Einstein Hospital, analyzing patient after BI in vigil coma stage,
Fabio Jakaitis; Ada Bianca; Abdulmacih Guazzelli
Efeito preventivo da fisioterapia na reduńŃo da incidĻncia de quedas em pacientes com Doenńa de Alzheimer Preventive effect of the physical therapy to minimize the occurrence of falls in patients with Alzheimer's Disease
SUMMARY The purpose of this review is to provide better understanding of the preventive effect resulted by the Physical Therapy in- tervention to minimize the occurrence of falls in patients with Alzheimer Disease. The Alzheimer Disease is the main cause of dementia between aged people. In recent years it has been showing an increase in the number of patients proportional
TetsadĻ CB Piermartiri; NaaraĒ Camboim Bezerra; Alexandre Ademar Hoeller
STF mantm cobrana de taxa para inscrio em vestibular A Procuradoria-Geral Federal em atuao conjunta com a Procuradoria Regional
STF mant├®m cobran├¦a de taxa para inscri├¦├Żo em vestibular A Procuradoria-Geral Federal em atua├¦├Żo sustentava a constitucionalidade da cobran├¦a da taxa de vestibular. Ao apreciar o caso, a Ministra Ellen a de inscri├¦├Żo em vestibular. Fonte: STF #12;
Incidencia de infecciones del torrente sanguĒneo por Staphylococcus aureus en pacientes crĒticamente enfermos en unidades de cuidado intensivo en Colombia 2004-2008 / Incidence bloodstream infection by Staphylococcus aureus in critically ill patients intensive care unit in Colombia 2004-2008.
??Contreras Villamizar, Kateir Mariel (2010) Incidencia de infecciones del torrente sanguĒneo por Staphylococcus aureus en pacientes crĒticamente enfermos en unidades de cuidado intensivo en Colombiaģ (more)
Contreras Villamizar, Kateir Mariel
Astronomia para/com crianńas carentes em Limeira
Em 2001, o Instituto Superior de CiĻncias Aplicadas (ISCA Faculdades de Limeira) iniciou um projeto pelo qual o Observat¾rio do Morro Azul empreendeu uma parceria com o Centro de PromońŃo Social Municipal (CEPROSOM), instituińŃo mantida pela Prefeitura Municipal de Limeira para atender crianńas e adolescentes carentes. O CEPROSOM contava com dois projetos: Projeto Centro de ConvivĻncia Infantil (CCI) e Programa Crianńa e Adolescente (PCA), que atendiam crianńas e adolescentes em Centros Comunitßrios de diversas ßreas da cidade. Esses projetos tĻm como prioridades estabelecer atividades prazerosas para as crianńas no sentido de retirß-las das ruas. Assim sendo, as crianńas passaram a ter mais um tipo de atividade - as visitas ao observat¾rio. Este painel descreve as vßrias fases do projeto, que envolveu: reuni§es de planejamento, curso de Astronomia para as orientadoras dos CCIs e PCAs, atividades relacionadas a visitas das crianńas ao Observat¾rio, proposta de construńŃo de gn¶mons e rel¾gios de Sol nos diversos Centros Comunitßrios de Limeira e divulgańŃo do projeto na imprensa. O painel inclui discuss§es sobre a aprendizagem de crianńas carentes, relatos que mostram a postura das orientadoras sobre a pertinĻncia do ensino de Astronomia, relatos do monitor que fez o atendimento no Observat¾rio e o que o n·mero de crianńas atendidas representou para as atividades da instituińŃo desde o inĒcio de suas atividades e, em particular, em 2001. Os resultados sŃo baseados na anßlise de relatos das orientadoras e do monitor do Observat¾rio, registros de visitas e matķrias da imprensa local. Conclui com uma avaliańŃo do que tal projeto representou para as Instituiń§es participantes. Para o Observat¾rio, em particular, foi feita uma anßlise com relańŃo Ós outras modalidades de atendimentos que envolvem alunos de escolas e p·blico em geral. Tambķm ķ abordada a questŃo do compromisso social do Observat¾rio na educańŃo do p·blico em questŃo.
Bretones, P. S.; Oliveira, V. C.
Quantitation of PET data with the EM reconstruction technique
The expectation maximization (EM) algorithm offers high spatial resolution and excellent noise reduction with low statistics PET data, since it incorporates the Poisson nature of the data. The main difficulties are long computation times, difficulties to find appropriate criteria to terminate the reconstruction and to quantify the resulting image data. In the present work a modified EM algorithm has been implements on a VAX 11/780. Its capability to quantify image data has been tested in phantom studies and in two clinical cases, cerebral blood flow studies and dopamine D2-receptor studies. Data from phantom studies indicate the superiority of images reconstructed with the EM technique compared to images reconstructed with the conventional filtered back-projection (FB) technique in areas with low statistics. At higher statistics the noise characteristics of the two techniques coincide. Clinical data support these findings.
Rosenqvist, G.; Dahlbom, M.; Erikson, L.; Bohm, C.; Blomqvist, G.
Longitudinal information and radiation damage in EM calorimetry
The SCC radiation field is higher than that encountered by previous hadron collider detectors. In particular, the electromagnetic (EM) calorimeter compartment sees the highest radiation dose. Since an EM calorimeter also makes the most precise energy measurement, special care must be lavished on this part of a calorimeter. Previous studies have concentrated on Monte Carlo examinations of 2 longitudinal compartments within the EM which can alleviate radiation damage. Recently, it was realized that a ``shower maximum`` detector, such as exists in CDF, also contains information of the conversion point of an electromagnetic shower. As such, it can potentially be used in a fashion analogous to the longitudinal compartments, although it is not designed to be optimized for this role.
Green, D.
The SCC radiation field is higher than that encountered by previous hadron collider detectors. In particular, the electromagnetic (EM) calorimeter compartment sees the highest radiation dose. Since an EM calorimeter also makes the most precise energy measurement, special care must be lavished on this part of a calorimeter. Previous studies have concentrated on Monte Carlo examinations of 2 longitudinal compartments within the EM which can alleviate radiation damage. Recently, it was realized that a shower maximum'' detector, such as exists in CDF, also contains information of the conversion point of an electromagnetic shower. As such, it can potentially be used in a fashion analogous to the longitudinal compartments, although it is not designed to be optimized for this role.
Propulsion From a Rotating EM Tether at Jupiter
The Jovian system with its rapid planetary rotation and strong magnetic field presents exciting opportunities for the use of electrodynamic (EM) tethers. Previous analysis for a radial, 10 km length tether demonstrated the possibility of propulsive forces as large as 50 Newtons near the planet. For orbital positions beyond about 2.5 Jovian radii, an EM tether can simultaneously be used for power and increases in the orbital altitude. Although the previous study demonstrated the physical feasibility of EM tether use at Jupiter, it did not address the issues of limited gravity gradient force for tether orientation and the practical use of this technology in an engineered system. This presentation will discuss these issues and current progress in an ongoing science/engineering transitional study.
Gallagher, D. L.; Moore, J.
EMS Stretcher "Misadventures" in a Large, Urban EMS System: A Descriptive Analysis of Contributing Factors and Resultant Injuries
Purpose. There is a paucity of data regarding EMS stretcher-operation-related injuries. This study describes and analyzes characteristics associated with undesirable stretcher operations, with or without resultant injury in a large, urban EMS agency. Methods. In the study agency, all stretcher-related ōmisadventuresö are required to be documented, regardless of whether injury results. All stretcher-related reports between July 1, 2009 and June 30, 2010 were queried in retrospective analysis, avoiding Hawthorne effect in stretcher operations. Results. During the year studied, 129,110 patients were transported. 23 stretcher incidents were reported (0.16 per 1,000 transports). No patient injury occurred. Four EMS providers sustained minor injuries. Among contributing aspects, the most common involved operations surrounding the stretcher-ambulance safety latch, 14/23 (60.9%). From a personnel injury prevention perspective, there exists a significant relationship between combative patients and crew injury related to stretcher operation, Fisher's exact test 0.048. Conclusions. In this large, urban EMS system, the incidence of injury related to stretcher operations in the one-year study period is markedly low, with few personnel injuries and no patient injuries incurred. Safety for EMS personnel and patients could be advanced by educational initiatives that highlight specific events and conditions contributing to stretcher-related adverse events. PMID:22606379
Goodloe, Jeffrey M.; Crowder, Christopher J.; Arthur, Annette O.; Thomas, Stephen H.
Mixture densities, maximum likelihood, and the EM algorithm
The problem of estimating the parameters which determine a mixture density is reviewed as well as maximum likelihood estimation for it. A particular iterative procedure for numerically approximating maximum likelihood estimates for mixture density problems is considered. This EM algorithm, is a specialization to the mixture density context of a general algorithm of the same name used to approximate maximum likelihood estimates for incomplete data problems. The formulation and theoretical and practical properties of the EM algorithm for mixture densities are discussed focussing in particular on mixtures of densities from exponential families.
Redner, R. A.; Walker, H. F.
Developments in the EM-CCD camera for OGRE
The Off-plane Grating Rocket Experiment (OGRE) is a sub-orbital rocket payload designed to advance the development of several emerging technologies for use on space missions. The payload consists of a high resolution soft X-ray spectrometer based around an optic made from precision cut and ground, single crystal silicon mirrors, a module of off-plane gratings and a camera array based around Electron Multiplying CCD (EM-CCD) technology. This paper gives an overview of OGRE with emphasis on the detector array; specifically this paper will address the reasons that EM-CCDs are the detector of choice and the advantages and disadvantages that this technology offers.
Tutt, James H.; McEntaffer, Randall L.; DeRoo, Casey; Schultz, Ted; Miles, Drew M.; Zhang, William; Murray, Neil J.; Holland, Andrew D.; Cash, Webster; Rogers, Thomas; O'Dell, Steve; Gaskin, Jessica; Kolodziejczak, Jeff; Evagora, Anthony M.; Holland, Karen; Colebrook, David
Waste fuel, EMS may save plant $1M yearly
A mixture of paper trash and coal ash fueling an Erie, Pa. General Electric plant and a Network 90 microprocessor-based energy-management system (EMS) to optimize boiler efficiency will cost about $3 million and have a three-to-four-year payback. Over half the savings will come from the avoided costs of burning plant-generated trash. The EMS system will monitor fuel requirements in the boiler and compensate for changes in steam demand. It will also monitor plant electrical needs and control the steam diverted for cogeneration. (DCK)
Barber, J.
Aquisi??o de Estreptococos Mutans e Desenvolvimento de C?rie Dental em Primog?nitos
Objetivo Avaliar o momento de aquisińŃo de estreptococos mutans (EM), desenvolvimento de cßrie dental e as varißveis a eles associadas no decorrer de 23 meses, em primogĻnitos de famĒlias de baixo nĒvel socioecon¶mico, desde os sete meses de idade. Mķtodo A amostra foi selecionada com base em mŃes densamente colonizadas por EM, incluindo todos os membros de 14 famĒlias que conviviam na mesma casa. Foram envolvidos no estudo 14 mŃes, pais e primogĻnitos e 8 parentes, na maioria av¾s. Exames clĒnicos e radiogrßficos iniciais determinaram os Ēndices de cßrie e condińŃo periodontal dos adultos. Contagens de EM foram feitas em todos os adultos nas duas primeiras visitas. Nas crianńas foram avaliados os nĒveis de EM, o n·mero de dentes e de cßries, em quatro visitas. Resultados A prevalĻncia de EM nos adultos foi alta, estando ausente em apenas um dos pais. EM foram detectados em 1, 2, 3 e 10 crianńas, respectivamente nas visitas #1, 2, 3 e 4. A cßrie dental foi detectada em apenas trĻs crianńas na ·ltima visita (aos 30 meses de idade), as quais apresentaram escores de EM significantemente maiores que as crianńas sem cßrie, na mesma visita. ConclusŃo Exclusivamente a condińŃo social de baixa renda e mŃes densamente colonizadas por EM nŃo sŃo sin¶nimo de colonizańŃo precoce e alta atividade de cßrie em crianńas cuidadas em casa. O desenvolvimento de cßrie estß significantemente associado a escores elevados de EM nas crianńas. PMID:22022218
NOCE, Erica; RUBIRA, Cassia Maria Fischer; da Silva ROSA, Odila Pereira; da SILVA, Salete Moura Bonifacio; BRETZ, Walter Antonio
de livro com ISBN ou paper em peri├│dico Qualis B2 ou inferior, 15 pontos por livro ou paper em (M├Īximo 100 pontos) 100 (*) 7 pontos por cap├Łtulo de livro com ISBN ou paper em peri├│dico Qualis B2 ou inferior, 15 pontos por livro ou paper em peri├│dico Qualis B1 ou superior. (**) 2,5 por ano/projeto (***) 2
Airborne EM for geothermal and hydrogeological mapping
Within the "VIGOR" project, aimed at assessing the geothermal potential of four regions in southern Italy, Airborne EM data have been acquired, modeled and interpreted. The system deployed was SkyTEM, a time-domain helicopter electromagnetic system designed for hydrogeophysical, environmental and mineral investigations. The AEM data provide, after data acquisition, analysis, processing, and modeling, a distribution volume of electrical resistivity, spanning an investigation depth from ground surface of few hundred meters, depending on resistivity condition. Resistivity is an important physical parameter for geothermal investigation, since it proved to be very effective in mapping anomalies due to hydrothermal fluid circulation, which usually has high salt content and produces clayey alteration minerals. Since the project required, among other issues, to define geothermal resources at shallow level, it was decided to perform a test with an airborne electromagnetic geophysical survey, to verify the advantages offered by the system in covering large areas in a short time. The geophysical survey was carried out in Sicily, Italy, in late 2011, over two test sites named "Termini" and "Western Sicily". The two areas were chosen on different basis. "Termini" area is covered by extensive geological surveys, and was going to be investigated also by means of electrical tomography in its northern part. Since geological condition of Sicily, even at shallow depth, is very complex, this area provided a good place for defining the resistivity values of the main geological units outcropping in the region. "Termini" survey has been also an occasion to define relations between resistivity distribution, lithological units and thermal conductivity. The "Western Sicily" area cover the main thermal manifestations of western Sicily, and the research target was to establish whether they are characterized by common hydrogeological or tectonic features that could be mapped by resistivity. SkyTEM data have been acquired in a series of flight lines and were then processed and inverted. In the "Termini" area the flight line spacing had 150 m separation. In the "Western Sicily" area two different line spacing were used: the 1 km spacing was used for the regional mapping, whereas for infill areas, around the main hydrothermal springs, the flight lines had 100 m spacing. The total number of flight line was 4580 km, and the explored surface was in excess of 2000 km2. After acquisition, data were processed to eliminate coupling with infrastructures, and noise. Inversions was then carried out using the quasi 3-D Spatially Constrained Inversion. The obtained resistivity volume has then been the base for a detailed lithological and geothermal interpretation. Lithological and geological maps were used to constrain surface condition and to understand the resistivity ranges of the different lithological units. On the base of resistivity values, lithological units were combined to establish the main litho-resistive units, then modeled at depth, down to achievable investigation depth. This detailed interpretative modeling was also the occasion of recognizing resistivity anomalies within carbonate units, which may possibly represent hydrogeological or hydrothermal bodies. The litho-resitive 3D model is now under investigation to verify how it can represent a viable way to image thermal conductivity variations at depth.
Menghini, A.; Manzella, A.; Viezzoli, A.; Montanari, D.; Maggi, S.
Quasi-Monte Carlo Sampling to improve the Efficiency of Monte Carlo EM
Quasi-Monte Carlo Sampling to improve the Efficiency of Monte Carlo EM Wolfgang Jank email@example.com November 17, 2003 Abstract In this paper we investigate an efficient implementation of the Monte Carlo EM al- gorithm based on Quasi-Monte Carlo sampling. The Monte Carlo EM algorithm is a stochastic version
Jank, Wolfgang
Mutagenic effectiveness and efficiency of EMS, DES and gamma-rays in rice
Data on chlorophyll mutation frequency after treatment with EMS, DES and gamma-rays and sequential administration of gamma-rays and the two alkylating agents in three varieties of rice have been used to work out quantitatively the effectiveness and efficiency of each mutagen and combination treatment. For effectiveness, the order is EMS > DES and for efficiency it is EMS > DES
M. L. H. Kaul; A. K. Bhan
Convergence results for the EM approach to mixtures of experts architectures
The Expectation-Maximization (EM) algorithm is an iterative approach to maximum likelihood parameter estimation. Jordan and Jacobs recently proposed an EM algorithm for the mixture of experts architecture of Jacobs, Jordan, Nowlan and Hinton (1991) and the hierarchical mixture of experts architecture of Jordan and Jacobs (1992). They showed empirically that the EM algorithm for these architectures yields significantly faster convergence
Michael I. Jordan; Lei Xu
O ser em metamorfose Jornal Circulao n. 55
ass├®dio moral quando, em 1912, Kafka escreveu o livro, mas a hist├│ria serve bem como met├Īfora para os Samsa, no livro, n├Żo desperta de novo humano e morre sozinho, reduzido ├Ā condi├¦├Żo de inseto, porque n├Żo
ISSN 0103-9741 Monografias em Cincia da Computao
Carlos Jos├® Pereira de Lucena T├Īcio Mauro Pereira de Campos M├┤nica Priscila Hernandez Moncada-9741 Editor: Prof. Carlos Jos├® Pereira de Lucena Novembro, 2009 Um Agente Especialista em Recomenda├¦├Żo de Pereira de Lucena, T├Īcio Mauro Pereira de Campos, M├┤nica Priscila Hernandez Moncada bneto
Endler, Markus
GEOBULLETIN NOvEmBEr 1sT
GEOBULLETIN NOvEmBEr 1sT 2013 - 1 - GeoBulletin is distributed weekly, by E-mail. Contributions are requested! If you have a news item, a request, an announcement etc. email it to email@example.com or leave it at the office, Room 225 by Noon on Wednesday. WEEKS LECTURE - FALL 2013 Nov. 1 Laura Wallace UT
Learning Active Basis Models by EM-Type Algorithms
Learning Active Basis Models by EM-Type Algorithms Zhangzhang Si1, Haifeng Gong1,2, Song-Chun Zhu1 scheme for learning image templates of object categories where the learning is not fully supervised. We and orientations to account for the deformations of object shapes. The model can be easily learned when the objects
Wu, Ying Nian
The EM Algorithm February 2/4, 2004
(energy) and the second term, which does not depend on , is the entropy. ┬Ę Thus, in the M-step, maximizing optimization easier. Expectation-Maximization (EM) Algorithm ┬Ę Iterative algorithm with two linked steps: E of a marginal probability: (; x) = log p(x|) = log z p(x, z|) which is the incomplete log likelihood. #12
Roweis, Sam
Fault Tolerant Control for EMS systems with sensor failure
The paper presents a method to recover the performance of an EMS (Electromagnetic suspension) under faulty air gap measurement. The controller is a combination of classical control loops, a Kalman estimator and analytical redundancy (for the air gap signal). In case of a faulty air gap sensor the air gap signal is recovered using the Kalman filter and analytical redundancy.
Konstantinos Michail; Argyrios Zolotas; Roger Goodall; John Pearson
Accurate EM-TV algorithm in PET with low SNR
PET measurements of tracers with a lower dose rate or short radioactive half life suffer from extremely low SNRs. In these cases standard reconstruction methods (OSEM, EM, filtered backprojection) deliver unsatisfactory and noisy results. Here, we propose to introduce nonlinear variational methods into the reconstruction process to make an efficient use of a-priori information and to attain improved imaging results.
Alex Sawatzky; Christoph Brune; Frank Wiibbeling; Thomas Kosters; Klaus Schafers; Martin Burger
Iterative EM Design of an MRI Magnet Using HTS Materials
Conventional superconducting MRI magnet electromagnetic (EM) design involves the critical parameters of the magnet field and dimensional requirements, plus the low temperature superconductor (LTS) wire properties. When using HTS material for an MRI magnet, in addition to the conventional characteristics of a superconductor, the wire and the joint resistance need also to be considered. This is mainly due to the
Minfeng Xu; Michele Ogle; Xianrui Huang; Kathleen Amm; Evangelos T. Laskaris
Resumo: O intuito desta exposińŃo ķ apresentar, com base na anßlise da experiĻncia da RED- U - Red Estatal de Docencia Universitaria constituĒda por universidades espanholas, uma reflexŃo em torno do desenvolvimento profissional do docente universitßrio no atual contexto de globalizańŃo. A referida rede representa um espańo para a difusŃo e o intercŌmbio de polĒticas, experiĻncias, metodologias e ferramentas utilizadas
Solange Maria Longhi
Cost-Effectiveness Analysis of Helicopter EMS for Trauma Patients
Study objective: To evaluate the cost-effectiveness of helicopter EMS for trauma patients. Methods: We applied a cost-effectiveness analysis from the service provider's perspective to cost and effectiveness estimates. The cost estimates comprise direct operating costs and additional survivors' hospital costs. The effectiveness estimates were calculated with the TRISS methodology from literature sources and data from a cohort of patients transported
Peter A Gearhart; Richard Wuerz; A. Russell Localio
University of Northern British Columbia Posting #12-079EM
duties, the Residence and Student Life Manager is responsible for the effective management of ResidenceUniversity of Northern British Columbia Posting #12-079EM Residence & Student Life Manager (Regular to a sustainable future. UNBC's main campus is located in Prince George, a city of nearly 80,000 people near
Northern British Columbia, University of
NUMBER: EM 1.00 (NEW) SECTION: Emergency Management
NUMBER: EM 1.00 (NEW) SECTION: Emergency Management SUBJECT: Emergency Notification System Policy: Michael Amiridis Issued by: Emergency Management I. Policy Per the Higher Education Opportunity Act the Carolina Alert system. a. Emergency Management Coordinator, University of South Carolina Division of Law
Almor, Amit
Leica EM AFS2 Automatic Freeze Substitution System
" excludes humidity and oxygen ┬Ę Fast UV polymerization with LED UV lamp Flexibility ┬Ę Any choice is polymerized under UV light in the EM AFS2 and can be cut and immuno labelled. LED UV lamp FS chamber with new. An integrated LED UV lamp allows immediate polymerization of the samples. Automatic process ┬Ę One step
Chapman, Michael S.
Hierarchical mixtures of experts and the EM algorithm
We present a tree-structured architecture for supervised learning. The statistical model underlying the architecture is a hierarchical mixture model in which both the mixture coefficients and the mixture components are generalized linear models (GLIMs). Learning is treated as a maximum likelihood problem; in particular, we present an expectation-maximization (EM) algorithm for adjusting the parameters of the architecture. We also develop
Michael I. Jordan; Robert A. Jacobs
Hierarchical Mixtures of Experts and the EM Algorithm
We present a tree-structured architecture for supervised learning. The statistical model underlying the architecture is a hierarchical mixture model in which both the mixture coefficients and the mixture components are generalized linear models (GLIM's). Learning is treated as a maximum likelihood problem; in particular, we present an Expectation-Maximization (EM) algorithm for adjusting the parameters of the architecture. We also develop
An EM algorithm for a semiparametric mixture model
An EM algorithm for a semiparametric mixture model Laurent Bordes1 Didier Chauveau2 Pierre Marne-la-Vall┬┤ee & CNRS January 2006 Abstract. Recently several authors considered finite mixture models not obvious, and when it occurs, inference methods are rather specific to the mixture model under
Vandekerkhove, Pierre
Symmetry-restrained flexible fitting for symmetric EM maps
Summary Many large biological macromolecules have inherent structural symmetry, being composed of a few distinct subunits, repeated in a symmetric array. These complexes are often not amenable to traditional high-resolution structural determination methods, but can be imaged in functionally relevant states using cryo-electron microscopy (cryo-EM). A number of methods for fitting atomic-scale structures into cryo-EM maps have been developed, including the molecular dynamics flexible fitting (MDFF) method. However, quality and resolution of the cryo-EM map are the major determinants of a methodÆs success. In order to incorporate knowledge of structural symmetry into the fitting procedure, we developed the symmetry-restrained MDFF method. The new method adds to the cryo-EM map-derived potential further restraints on the allowed conformations of a complex during fitting, thereby improving the quality of the resultant structure. The benefit of using symmetry-based restraints during fitting, particularly for medium to low-resolution data, is demonstrated for three different systems. PMID:21893283
Chan, Kwok-Yan; Gumbart, James; McGreevy, Ryan; Watermeyer, Jean M.; Sewell, B. Trevor; Schulten, Klaus
EM Structure-Based Accelerators Working Group Summary
This Working Group (WG) focused on EM Structure-Based Accelerators, which covers a broad area of mechanisms and experiments. Topics covered included dielectric wakefield accelerators (DWA), photonic bandgap accelerators (PBGA), inverse free electron lasers (IFEL), vacuum laser accelerators (VLA), other novel schemes, and supporting analysis and modeling. In addition, this WG was tasked at the Workshop with developing conceptual (strawman) designs
W. D. Kimura; S. M. Lidia
ISO 14001 EMS standard registration decisions among Canadian organizations
This study characterized the costs and benefits associated with adopting ISO 14001 environmental management system (EMS) standard, based on a survey of ISO 14001-registered organizations in Canada. Decision makers are contemplating whether it is necessary to register to one or more of the ISO and other international standards and, if so, which ones. Furthermore, an organization that has registered separate
Emmanuel K. Yiridoe; J. Stephen Clark; Geb E. Marett; Robert Gordon; Peter Duinker
A Science Service Feature 1 WHYTHE"EmHER ?
A Science Service Feature 1 WHYTHE"EmHER ? Dr. Charles F. Erooks, Secretary, American the plain white f l a g has a dark trh@&aLr f l a g above i t the prophesy is fair and warmer by Science Service Science Service, 1115 Conn. Ave., Washington, D .C . #12;
PAPEL DO EXERC═CIO F═SICO NA DISFUNŪ├O ENDOTELIAL DE PACIENTES COM S═NDROME METABėLICA E DIABETES MELLITUS The role of physical exercise in endothelial dysfunction of patients with Metabolic Syndrome and Diabetes Mellitus
RESUMO Pacientes com sĒndrome metab¾lica e diabetes mellitus tĻm morbidade e mortalidade cardiovascular aumentada. A disfunńŃo endotelial tem sido implicada na patogĻnese da doenńa vascular diabķtica. Essa funńŃo anormal ocorre precocemente antes da manifestańŃo da doenńa cardiovascular, caracterizando-se por reduńŃo do vasorelaxamento dependente do endotķlio. Neste sentido, intervenń§es com a L-arginina, drogas de reduńŃo lipĒdicas (estatinas), antioxidantes (vitamina C) e
Carlos Alberto da Silva; Josķ Carlos Grando
"Cada ser, em si, carrega o dom de ser capaz de ser feliz" : um estudo de caso baseado em Alfred Adler, Lev Vigotski e Gonzßlez Rey.
??DissertańŃo (mestrado)ŚUniversidade de BrasĒlia, Faculdade de EducańŃo, 2011. As crianńas que apresentam qualquer marca em seu desenvolvimento, seja um defeito fĒsico, ausĻncia sensorial ou, atķģ (more)
Batista, Anelice da Silva
Algoritmos e Estruturas de Dados II IBm1022 Departamento de Computao e Matemtica 2 Semestre/2012
paciente contendo os campos: paciente-id, nome, sexo, idade. A chave ├® campo paciente-id, um inteiro. O arquivo paciente deve ser criado contendo os seguintes registros: Registro paciente-id nome sexo idade 1 1 Sexo Idade 3 3 Alfredo Piva m 25 Posicionar em qual registro? 5 Posicionando... Ponteiro no registro
Baranauskas, Jos├® Augusto
Composting of rice straw with effective microorganisms (EM) and its influence on compost quality
This study aims to assess the effect of EM application on the composting process of rice straw with goat manure and green waste and to evaluate the quality of both compost treatments. There are two treatment piles in this study, in which one pile was applied with EM and another pile without EM. Each treatment was replicated three times with 90Ādays of composting duration. The parameters for the temperature, pH, TOC and C/N ratio, show that decomposition of organic matter occurs during the 90-day period. The t-test conducted shows that there is a significant difference between compost with EM and compost without EM. The application of EM in compost increases the macro and micronutrient content. The following parameters support this conclusion: compost applied with EM has more N, P and K content (P?0.05) compared to compost without EM. Although the Fe in compost with EM is much higher (P?0.05) than in the compost without EM, for Zn and Cu, there is no significant difference between treatments. This study suggests that the application of EM is suitable to increase the mineralization in the composting process. The final resultant compost indicated that it was in the range of the matured level and can be used without any restriction. PMID:23390930
Mķtodo numķrico das diferenńas finitas no domĒnio do tempo aplicado a ondas Alfvķn em plasma astrofĒsico
Ondas Alfvķn em plasma astrofĒsico tĻm sido objeto de intenso estudo nas ·ltimas dķcadas pelo fato de apresentarem papel importante em muitas ßreas de pesquisa na astrofĒsica. Particularmente sŃo importantes no mecanismo de aquecimento da coroa solar; em ventos estelares; em jatos galßcticos e extragalßcticos; em discos protoestelares, etc. A formulańŃo para diferenńas finitas no domĒnio do tempo (FDTD), aplicada a plasma magnetizado ķ desenvolvida para estudo das propriedades de ondas Alfvķn em trĻs dimens§es (3D-FDTD). O mķtodo ķ aplicado inicialmente a um plasma homogĻneo e isotķrmico imerso em uma regiŃo com campo magnķtico externo B0, que sofre uma pequena perturbańŃo. Uma vez gerada a onda, esta perturbańŃo ķ retirada e, entŃo analisamos a evoluńŃo temporal das ondas, bem como a forma de seu amortecimento.
Dos Santos, L. C.; Kintopp, J. A.; Jatenco-Pereira, V.; Opher, R.
Environmental Restoration and Waste Management (EM) program: An introduction
This booklet introduces the reader to the mission and functions of a major new unit within the US Department of Energy (DOE): the Office of Environmental Restoration and Waste Management (EM). The Secretary of Energy established EM in November 1989, implementing a central purpose of DOE's first annual Environmental Restoration and Waste Management Five-Year Plan, which had appeared three months earlier. The contents of this booklet, and their arrangement, reflect the annual update of the Five-Year Plan. The Five-Year Plan supports DOE's strategy for meeting its 30-year compliance and cleanup goal. This strategy involves: focusing DOE's activities on eliminating or reducing known or recognized potential risks to worker and public health and the environment, containing or isolating, removing, or detoxifying onsite and offsite contamination, and developing technology to achieve DOE's environmental goals.
Superconducting Electromagnetic Suspension (EMS) system for Grumman Maglev concept
The Grumman developed Electromagnetic Suspension (EMS) Maglev system has the following key characteristics: a large operating airgap--40 mm; levitation at all speeds; both high speed and low speed applications; no deleterious effects on SC coils at low vehicle speeds; low magnetic field at the SC coil--less than 0.35 T; no need to use non-magnetic/non-metallic rebar in the guideway structure; low magnetic field in passenger cabin--approximately 1 G; low forces on the SC coil; employs state-of-the-art NbTi wire; no need for an active magnet quench protection system; and lower weight than a magnet system with copper coils. The EMS Maglev described in this paper does not require development of any new technologies. The system could be built with the existing SC magnet technology.
Kalsi, Swarn S.
EvoluńŃo temporal de discos circunstelares em estrelas Be
A pesquisa do mecanismo que leva uma estrela do tipo Be a perder massa e formar um envelope circunstelar, nomeado como fen¶meno Be, ķ uma questŃo em aberto, intrigante, e que adquire contornos interessantes em face Ós informań§es espectrosc¾picas de alta resoluńŃo. Nesta ·ltima dķcada, consolida-se a idķia de que a forma destes envelopes ķ de tipo disc¾ide, obedecendo a uma lei Kepleriana de velocidades, e mais ainda, recentemente hß evidĻncias de que a distribuińŃo de matķria nestes discos pode assumir um carßter de anel. Medidas de algumas dimens§es de discos circunstelares puderam ser obtidas pela anßlise de espectros de alta resoluńŃo e alta relańŃo sinal-ruĒdo para as estrelas Be: alpha Eri (HD 10144, B3Vpe), omicron And (HD 217675, B6IIIpe), e eta Cen (HD el972, B1.5Vne), no perĒodo dos anos de 1991 a 2001. Alguns modelos clßssicos de envelope predizem uma distribuińŃo de massa que decresce suavemente a partir da superfĒcie estelar. Entretanto, considerando que a separańŃo de picos de emissŃo em perfis de linhas do HeI e H-alpha, alargados por efeitos cinemßticos, ķ funńŃo do raio estelar e da velocidade rotacional projetada (vsini); nossos resultados sugerem a presenńa de um anel de matķria circunstelar, que aparece logo ap¾s a ejeńŃo do material fotosfķrico, imediatamente acima da superfĒcie estelar, e que se expande para raios maiores ao longo do tempo, eventualmente desconectando-se da superfĒcie por uma regiŃo de densidade de matķria mĒnima. Tais interpretań§es revivem a idķia de que anķis de matķria circunstelar podem ser os responsßveis por algumas variabilidades em perfis de linhas de emissŃo, como as variań§es V/R.
Fernandes, M. V. M.; Leister, N. V.; Levenhagen, R. S.
Pereira Sardinha Carlos Jos├® Pereira de Lucena Departamento de Inform├Ītica PONTIF├ŹCIA UNIVERSIDADE;Monografias em Ci├¬ncia da Computa├¦├Żo, No. 32/05 ISSN: 0103-9741 Editor: Prof. Carlos Jos├® Pereira de Lucena * Carolina Howard Felic├Łssimo, Jos├® Alberto Pereira Rodrigues Sardinha, Carlos Jos├® de Pereira de Lucena
Override problems lead chain to EMS with remote monitor
When R.B. Furniture Co. employees began overriding the Trimax energy management system (EMS) in the company's 61 showrooms, the company shifted to En-Log units for the remaining stores despite the 9- to 22-month payback of the Trimax systems. Remote communications allow monitoring of the En-Log systems and prevent overrides. The case history compares specifications and costs for the two systems. (DCK)
EMS users find solutions to voltage-surge problems
The microchips in energy-management systems (EMS) are especially vulnerable to damage due to voltage surges, but the addition of surge suppressors to cut off the peak of spikes at a certain level or the use of fiber-optic cable that transmits light signals instead of electricity can overcome the problem. Users are often unaware that lightning, utility-grid switching, or the shutting down of large equipment can cause surges that garble computer information. (DCK)
PUC ISSN 0103-9741 Monografias em Ci├¬ncia da Computa├¦├Żo n┬░ 05/06 IPTV Conceitos, Padr├Ąes e Solu├¦├Ąes Computa├¦├Żo, No. 05/06 ISSN: 0103-9741 Editor: Prof. Carlos Jos├® Pereira de Lucena Fevereiro, 2006 IPTV ) ! %& % * & + %& %& 1 >1 , 2 Solu├¦├Ąes e provedores de servi├¦o de IPTV 2.1 Solu├¦├Ąes : %) % %) % 6
Da universidade para o mercado de trabalho em onze pases
Universia est├Ī a ser lan├¦ado em v├Īrias institui├¦├Ąes de ensino superior portuguesas. Rede ibero-americana regista por m├¬s 195 mil ofertas ANA BELA FERREIRA Desde quinta-feira que os 23 mil alunos da Universidade a pr├│-rei- tora, Ana Nunes de Almeida. Ao aderir a esta plataforma, que con- centra n├Żo s├│ ofertas
Instituto de Sistemas e Robotica
Perda de massa em ventos empoeirados de estrelas supergigantes
Em praticamente todas as regi§es do diagrama HR, as estrelas apresentam evidĻncias observacionais de perda de massa. Na literatura, pode-se encontrar trabalhos que tratam tanto do diagn¾stico da perda de massa como da construńŃo de modelos que visam explicß-la. O amortecimento de ondas Alfvķn tem sido utilizado como mecanismo de acelerańŃo de ventos homogĻneos. Entretanto, sabe-se que os envelopes de estrelas frias contĻm grŃos s¾lidos e molķculas. Com o intuito de estudar a interańŃo entre as ondas Alfvķn e a poeira e a sua conseq³Ļncia na acelerańŃo do vento estelar, Falceta-Gonńalves & Jatenco-Pereira (2002) desenvolveram um modelo de perda de massa para estrelas supergigantes. Neste trabalho, apresentamos um estudo do modelo acima proposto para avaliar a dependĻncia da taxa de perda de massa com alguns parŌmetros iniciais como, por exemplo, a densidade r0, o campo magnķtico B0, o comprimento de amortecimento da onda L0, seu fluxo f0, entre outros. Sendo assim, aumentando f0 de 10% a partir de valores de referĻncia, vimos que aumenta consideravelmente, enquanto que um aumento de mesmo valor em r0, B0 e L0 acarreta uma diminuińŃo em .
Vidotto, A. A.; Jatenco-Pereira, V.
Hydration-layer models for cryo-EM image simulation
To compare cryo-EM images and 3D reconstructions with atomic structures in a quantitative way it is essential to model the electron scattering by solvent (water or ice) that surrounds protein assemblies. The most rigorous method for determing the density of solvating water atoms for this purpose has been to perform molecular-dynamics (MD) simulations of the protein-water system. In this paper we adapt the ideas of bulk-water modeling that are used in the refinement of X-ray crystal structures to the cryo-EM solvent-modeling problem. We present a continuum model for solvent density which matches MD-based results to within sampling errors. However, we also find that the simple binary-mask model of Jiang and Br³nger (1994) performs nearly as well as the new model. We conclude that several methods are now available for rapid and accurate modeling of cryo-EM images and maps of solvated proteins. PMID:22609687
Shang, Zhiguo; Sigworth, Fred J.
The US DOE-EM International Program - 13004
The U.S. Department of Energy (DOE) Office of Environmental Management (EM) conducts international collaboration activities in support of U.S. policies and objectives regarding the accelerated risk reduction and remediation of environmental legacy of the nations' nuclear weapons program and government sponsored nuclear energy research. The EM International Program supported out of the EM Office of the Associate Principal Deputy Assistant Secretary pursues collaborations with foreign government organizations, educational institutions and private industry to assist in identifying technologies and promote international collaborations that leverage resources and link international experience and expertise. In fiscal year (FY) 2012, the International Program awarded eight international collaborative projects for work scope spanning waste processing, groundwater and soil remediation, deactivation and decommissioning (D and D) and nuclear materials disposition initiatives to seven foreign organizations. Additionally, the International Program's scope and collaboration opportunities were expanded to include technical as well as non-technical areas. This paper will present an overview of the on-going tasks awarded in FY 2012 and an update of upcoming international activities and opportunities for expansion into FY 2013 and beyond. (authors)
Elmetti, Rosa R.; Han, Ana M.; Williams, Alice C. [Department of Energy, Office of Environmental Management, 1000 Independence Ave. SW, Washington, DC 20585 (United States)] [Department of Energy, Office of Environmental Management, 1000 Independence Ave. SW, Washington, DC 20585 (United States)
Improving EM&V for Energy Efficiency Programs (Fact Sheet)
This fact sheet describes the objectives of the U.S. Department of Energy Uniform Methods Project to bring consistency to energy savings calculations in U.S. energy efficiency programs. The U.S. Department of Energy (DOE) is developing a framework and a set of protocols for determining gross energy savings from energy efficiency measures and programs. The protocols represent a refinement of the body of knowledge supporting energy efficiency evaluation, measurement, and verification (EM&V) activities. They have been written by technical experts within the field and reviewed by industry experts. Current EM&V practice allows for multiple methods for calculating energy savings. These methods were developed to meet the needs of energy efficiency program administrators and regulators. Although they served their original objectives well, they have resulted in inconsistent and incomparable savings results - even for identical measures. The goal of the Uniform Methods Project is to strengthen the credibility of energy savings determinations by improving EM&V, increasing the consistency and transparency of how energy savings are determined.
Aneurisma de artķria cerebral em crianńa com sĒndrome da imunodeficiĻncia adquirida: relato de caso
RESUMO - A dilatańŃo aneurismßtica dos vasos do polĒgono de Willis ķ manifestańŃo incomum da infecńŃo pelo vĒrus da imunodeficiĻn cia adquirida (HIV), tendo sido relatados, atķ o momento, 15 casos na literatura. O presente estudo tem por objetivo relatar um novo caso dessa apresentańŃo rara, alķm de revisar aspectos importantes relacionados Ó mesma. Um paciente, do sexo masculino, 6
Arnolfo de Carvalho Neto; Isac Bruck; Luiz Otßvio de Mattos Coelho; Cristina Rodrigues da Cruz; Cristian Bark Liu; Andrķ Francisco Gomes; SĒlvio Atsushi Ogata; Tony Tannous Tahan
Retrospectively exploring the importance of items in the decision to leave the emergency medical services (EMS) profession and their relationships to life satisfaction after leaving EMS and likelihood of returning to EMS.
An exit survey was returned by a sample of 127 respondents in fully compensated positions who left the EMS profession, most within 12 months prior to filling out the exit survey. A very high percentage continued to work after leaving EMS. Respondents were asked to rate the importance of each of 17 items in affecting their decision to leave EMS. A higher than anticipated response to a "not applicable" response choice affected the usability of 8 of these items. Nine of the 17 items had at least 65 useable responses and were used for further analysis. Within these 9, stress/burnout and lack of job challenges had the highest importance in affecting the decision to leave EMS, while desire for better pay and benefits had the lowest importance. Desire for career change was positively related to life satisfaction after leaving EMS and negatively related to likelihood of returning to EMS. Stress/burnout was positively related to life satisfaction after leaving EMS. Study limitations and future research issues are briefly discussed. PMID:21695362
Blau, Gary; Chapman, Susan
Inhomogeneous Media 3D EM Modeling with Integral Equation Method
In general, only the half space of earth is considered in electromagnetic exploration. However, for the long bipole source, because the length is close to the height of ionosphere and also most offsets between source and receivers are equal or larger than the height of ionosphere, the effect of ionosphere on the electromagnetic (EM) field should be considered when observation is carried at a very far (about several thousands kilometers) location away from the source. At this point the problem becomes one which should contain ionosphere, atmosphere and earth that is ōearth-ionosphereö case. There are a few of literatures to report the electromagnetic field results which is including ionosphere, atmosphere and earth media at the same time. We firstly calculate the electromagnetic fields with the traditional controlled source (CSEM) configuration using integral equation (IE) method for a three layers earth-ionosphere model. The modeling results agree well with the half space analytical results because the effect of ionosphere for this small scale bipole source can be ignorable. The comparison of small scale three layers earth-ionosphere modeling and half space analytical resolution shows that the IE method can be used to modeling the EM fields for long bipole large offset configuration. In order to discuss EM fieldsÆ characteristics for complicate earth-ionosphere media excited by long bipole source in the far-field and wave-guide zones, we first modeled the decay characters of electromagnetic fields for three layers earth-ionosphere model. Because of the effect of ionosphere, the earth-ionosphere electromagnetic fieldsÆ decay curves with given frequency show that there should be an extra wave guide zone for long bipole artificial source, and there are many different characters between this extra zone and far field zone. They are: 1) the amplitudes of EM fields decay much slower; 2) the polarization patterns change; 3) the positions better to measure Zxy and Zyx change; 4) there exits the polarization ellipse of electric and magnetic fields; 5) the long axis direction of the polarization ellipse in wave guide zone changes comparing to quasi static EM fields. In order to further model the EM fields for complex inhomogeneous media, we conducted the EM fields modeling for Biyang depressed basin of China. The bottom depth of the oil basin is about 8km. We added one ionosphere layer with thickness 100km and resistivity 104 Ohm-m and one atmosphere layer with thickness 100km and resistivity 1014 Ohm-m over the solid earth surface during the forward modeling. For easily to compare with the 2D seismic exploration result, we conducted the apparent resistivity modeling of equatorial array for the same survey line as seismic did for an 50km long bipole source with offset 400km and the same frequencies as that used for above three layers model. The modeling apparent resistivity pseudo-section has clearly shown the oil basin geology structure.
di, Q.; Wang, R.; An, Z.; Fu, C.; Xu, C.
-80, 2011. Dispon├Łvel em: http://www.portal.fae.ufmg.br/seer/index.php/ensaio/article/viewFile/309/715 Leia-162, 2000. Dispon├Łvel em: http://www.portal.fae.ufmg.br/seer/index.php/ensaio/article/viewFile/21/52. 5 diferentes abordagens. Rev. Ensaio, v.13, n.3, p.67-80, 2011. Dispon├Łvel em: http://www.portal.fae.ufmg.br/seer
0.5setgray00.5setgray1 Determinao de coeficientes em equaes
de Imagens em Medicina Nuclear ┬Ę SPECT ┬Ł Single Photon Emission Tomography, ┬Ł p. 13/7 #12;T├®cnicas para Gera├¦├Żo de Imagens em Medicina Nuclear ┬Ę SPECT ┬Ł Single Photon Emission Tomography, ┬Ę PET ┬Ł Positron Emission Tomograpy; ┬Ł p. 13/7 #12;T├®cnicas para Gera├¦├Żo de Imagens em Medicina Nuclear ┬Ę SPECT
Cipolatti, Rolci
1 UNIVERSIDADE DE BRAS├ŹLIA PROGRAMA DE RESID├?NCIA M├?DICO VETERIN├üRIA EM ANATOMIA PATOL├?GICA ANATOMIA PATOL├?GICA VETERIN├üRIA PARA O PRIMEIRO PER├ŹODO LETIVO DE 2011 1. PRE├?MBULO 1.1 O Presidente da Veterin├Īria em Anatomia Patol├│gica Veterin├Īria, em conformidade com as exig├¬ncias do Regulamento deste
EmNets 2006 Life Under your Feet 1 Life Under your Feet
EmNets 2006 Life Under your Feet 1 Life Under your Feet: A Wireless Soil Ecology Sensor Network R the Beginning... EmNets 2006 Life Under your Feet 2 ┬Ę The Cast ┬Ę An ecologist: Katalin Szlavecz ┬Ę An undergrad Step EmNets 2006 Life Under your Feet 3 ┬Ę The sensors were thoroughly tested in the lab ┬Ę 2 out of 6
Amir, Yair
UNIVERSIDADE DE BRASLIA (UnB) PROGRAMA DE PS-GRADUAO EM ECONOMIA
UNIVERSIDADE DE BRAS├ŹLIA (UnB) PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA EDITAL No. 06/2013 SELE├?├?O DE CANDIDATOS ├?S VAGAS DO PROGRAMA DE P├?S-GRADUA├?├?O EM ECONOMIA, PARA O CURSO DE MESTRADO PROFISSIONAL, ├üREA DE CONCENTRA├?├?O EM ECONOMIA DO SETOR P├?BLICO, PARA O PRIMEIRO PER├ŹODO LETIVO DE 2014. 1. PRE├?MBULO 1.1 O
EMS-CO2 Welding: A New Approach to Improve Droplet Transfer Characteristics and Welding Formation
In this article, to improve the stability of droplet transfer and reduce the spatter of pure carbon dioxide gas shield welding (CO2 welding), we propose a new welding method called EMS-CO2 welding by applying an additional longitudinal electromagnetic field to a CO2 welding process (abbr. EMS-CO2 welding). The characteristics of droplet transfer, welding formation and microstructure between EMS-CO2 welding and
Jian Luo; Qian Luo; Xiangjie Wang; Xiaochuan Wang
Evaluation of the Sympathetic Nervous System Using Heart Rate Variability and Plasma Hormones in Hypertensive Patients Treated with Cilazapril and Atenolol
In a double-blind placebo-controlled parallel study, we assessed basal and post-therapeutic sympathetic activity both in supine and standing positions in mildly to moderately hypertensive patients by two different methods: frequency domain indices of heart rate variability (HRV) and plasma levels of both noradrenaline (NA) and its metabolite, 3,4-dihydroxyphenylglycol (DOPEG). Patients were evaluated on placebo and after 8 weeks of treatment
Manuel Campelo; Jorge Pol¾nia; Paula SerrŃo; Mario Cerqueira-Gomes
Melasma extra-facial : avaliańŃo clĒnica, histopatol¾gica e imuno-histoquĒmica em estudo caso-controle.
??Fundamentos: O melasma extra-facial ķ dermatose freq³ente na prßtica clĒnica dermatol¾gica. Apresenta caracterĒsticas especiais em relańŃo tanto aos aspectos clĒnicos como aos provßveis fatores etiopatogĻnicos.ģ (more)
Clarice Gabardo Ritter
ADMINISTRATION AND COLLEGE MASTERS 343342 ADMINISTRATION Emergency Medical Service (EMS) .................................................... Bill Taylor
ADMINISTRATION AND COLLEGE MASTERS 343342 ADMINISTRATION Emergency Medical Service (EMS .................................................. Adria Baker Intramural Sports. Lieberman Media Relations and Information ................................................ Margot Dimond
Richards-Kortum, Rebecca
AdministrańŃo peridural de morfina ou tramadol em cŃes: efeito analgķsico e cardiorespirat¾rio.
??Objetivou-se com este estudo duplo cego avaliar o efeito analgķsico e cardiorrespirat¾rio da morfina ou tramadol quando utilizados via peridural, em cadelas submetidas Ó ovariossalpingohisterectomiaģ (more)
Celso Sawaya Neves
Motivaciones, expectativas y satisfacci¾n de pacientes atendidos en consulta docente-asistencial de homeopatĒa en la Universidad Nacional de Colombia 2009-2010 / Motivations, expectation, and satisfaction of patients seen in consultation-care teaching homeopathy at the National University of Colombia 2009-2010.
??Ducuara Cruz, Diana (2010) Motivaciones, expectativas y satisfacci¾n de pacientes atendidos en consulta docente-asistencial de homeopatĒa en la Universidad Nacional de Colombia 2009-2010 / Motivations,ģ (more)
Ducuara Cruz, Diana
General 4-week toxicity study with EMS in the rat.
In this subacute toxicity study, ethyl methanesulfonate (EMS) was administered daily by oral gavage to SPF-bred Wistar rats of both sexes at dose levels of 20, 60 and 180/120 mg/kg body weight (bw)/day for a period of 28 days (for 19 days in the high-dose group). A control group was treated similarly with the vehicle, bidistilled water, only. The groups comprised 10 animals per sex, which were sacrificed after 28 days, respectively 19 days in the high-dose group, of treatment. Additional five rats per sex and group were treated accordingly and then allowed a 14 days treatment-free recovery period. Additional six rats per sex and group (three rats per sex in the control group) were treated accordingly and used for hemoglobin adduct analysis after EMS exposure. All animals survived until their scheduled necropsy. Treatment with EMS had a direct dose-dependent effect on food consumption and consequently on body weight at doses > or =20mg/kgbw/day in male rats and at > or =60 mg/kgbw/day in females rats. Hence, treatment with the high dose of 180 mg/kgbw/day had to be interrupted for 9 days after which, the animals were re-dosed at 120 mg/kgbw/day. This dose was also poorly tolerated over the remaining two treatment weeks causing again a marked reduction in food consumption and body weight. A dose of 60 mg/kgbw/day was moderately tolerated over 4 weeks treatment with mean daily food consumption and body weight distinctly lower than in controls. Primary targets of systemic toxicity were the hematopoietic system, thymolymphatic system and sexual organs. Characteristic changes in hematology parameters were decreased red blood cell counts, hematocrit, and hemoglobin concentration. White blood cell counts were also decreased due to reduced lymphocyte and granulocyte populations of each fraction. The corresponding histopathology findings were fatty atrophy of bone marrow and minimal hypocellularity of the white pulp of the spleen. Similarly, treatment with EMS caused an involution of the thymolymphatic system characterized by decreased organ weight of thymus, lymph nodes, and spleen microscopically associated with atrophy of the thymus and hypocellularity of Peyer's patches, lymph nodes and the white pulp of the spleen. The effects on sexual organs included lower organ weight/reduced size for testes, epididymides, seminal vesicles, prostate, and uterus. Tubular atrophy, single cell necrosis of the germ cells and in epididymides reduced spermatozoa were recorded microscopically. The described findings occurred at doses of 60 and 180/120 mg/kgbw/day and were dose-dependent with regard to incidence and severity. Other target organs were the pancreas (acinar cell vacuolation), thyroid gland (follicular cell hypertrophy), and salivary gland (secretory depletion of convoluted ducts). The systemic exposure to EMS was monitored by hemoglobin ethylvaline adduct measurement. The concentration of hemoglobin ethylvaline adducts was linear with the dose and accumulated 11-26-fold over the treatment period. In summary, decreases in food consumption and body weight were the dose-limiting effects of treatment with EMS. Organ toxicity was characterized by depression of cell proliferation (hematopoiesis and spermatogenesis) and changes suggestive of reduced metabolism and/or physiological imbalances (e.g. thymolymphatic system and thyroid gland) without signs of inflammatory or necrotic lesions. For some findings, especially the effects on the thymolymphatic system and sexual organs, it cannot be excluded that starvation-like condition contributed to the occurrence of such changes. The low dose of 20 mg/kgbw/day was basically free of adverse effects despite of a clear evidence for hemoglobin adducts. PMID:19442710
Pfister, Thomas; Eichinger-Chapelon, Anne
Transmission characteristics of EM wave in a finite thickness plasma
One of the key factors for solving the problems of re-entry communication interruption is electromagnetic (EM) wave transmission characteristics in a plasma. Theoretical and experimental studies were carried out on specific transmission characteristics for different plasma sheath characteristic under thin sheath condition in re-entry state. The paper presents systematic studies on the variations of wave attenuation characteristics versus plasma sheath thickness L, collision frequency ?, electron density n e and wave working frequency f in a ? 800mm high temperature shock tube. In experiments, L is set to 4 cm and 38 cm. ? is 2 GHz and 15 GHz. n e is from 1ū1010 cm-3 to 1ū1013 cm-3, and f is set to 2, 5, 10, 14.6 GHz, respectively. Meanwhile, Wentzel-Kramers-Brillouin (WKB) and finite-difference time-domain (FDTD) methods are adopted to carry out theoretical simulation for comparison with experimental results. It is found that when L is much larger than EM wavelength ? (thick sheath) and ? is large, the theoretical result is in good agreement with experimental one, when sheath thickness L is much larger than ?, while ? is relatively small, two theoretical results are obviously different from the experimental ones. It means that the existing theoretical model can not fully describe the contribution of ?. Furthermore, when L and ? are of the same order of magnitude (thin sheath), the experimental result is much smaller than the theoretical values, which indicates that the current model can not properly describe the thin sheath effect on EM attenuation characteristics.
Zhu, Nai-Yi; Huang, Li-Shun; Wu, Bin; Yu, Xi-Long; Wu, Run-Hui; Meng, Gang; Ren, Ai-Min; Hu, Xin-Tian
Epidemiology of major incidents: an EMS study from Pakistan
Background A major incident is defined as an event that owing to the number of casualties has the potential to overwhelm the available resources. This paper attempts to describe the incidence and epidemiology of major incidents dealt with by a government-run emergency medical service (EMS) in the Punjab province of Pakistan, a developing country in South Asia. A major incident in this EMS is defined as any incident that produces three or more patients, or any incident in which extraordinary resources are needed. Methods All the calls received by an EMS Rescue 1122 were studied over a 6-month period. Calls that were defined as major incidents were identified, and further details were sought from the districts regarding these incidents. Questions specifically asked were the type of incident, time of the incident, response time for the incident, the resources needed, and the number of dead and injured casualties. Retrospective data were collected from the submitted written reports. Results Road traffic crashes (RTCs) emerged as the leading cause of a major incident in the province of Punjab and also led to the greatest number of casualties, followed by fire incidents. The total number of casualties was 3,380, out of which 73.7% were RTC victims. There was a high rate of death on the scene (10.4%). Certain other causes of major incidents also emerged, including violence, gas explosions and drowning. Conclusion Road traffic crashes are the most common cause of a major incident in developing countries such as Pakistan. Injury prevention initiatives need to focus on RTCs. PMID:21798011
A compulsator driven rapid-fire EM-gun
A compulsator-driven railgun is an attractive alternative to the homopolar generator-inductor-switch configuration, especially for repetitive duty. A conceptual design of a rapid-fire EM-gun system is presented. The generator is sized to accelerate a 0.08-kg projectile to 2 to 3 km/s at a 60 pulse-per-second repetition rate. Initial design parameters are discussed, and example current and velocity waveforms are given. The generator is discharged at the proper phase angle to provide a current zero just as the projectile exits the muzzle of the railgun.
Pratap, S.B.; Bird, W.L.
Hospital picks EMS from 3 guaranteed savings bids
A Wheeling, WV medical center stipulated $54,000 guaranteed annual savings from all bidders when it selected an MCC Powers System 600 energy management system (EMS) from among several bidders. A DOE grant will reduce the payback period to one year. A staff energy audit was the basis for the guaranteed savings figure. Programming ease and the ability to display building systems were positive features of the System 600 besides the low bid, but visits to other facilities using the system were a major factor in the decision. (DCK)
SEI: Junior E&M I Course Materials - Electrodynamics
This is a collection of resources for teaching electrodynamics. Included are homework questions, concept tests, student tutorials, and information about common student difficulties in the topic and ways to address these difficulties. This material was developed as part of a education research-based course transformation for junior level E&M. All of the resources developed for this course are available, sorted by individual topic and type, at http://www.compadre.org/psrc/items/Relations.cfm?ID=7891. Because this topic is not typically taught in depth in the courses used in developing these course materials, these materials are less complete than the other sections.
Pollock, Steven J.; Chasteen, Stephanie V.
SEI: Junior E&M I Course Materials - Math Fundamentals
This is a collection of resources for teaching mathematical fundamentals of electro- and magnetostatics constructed over the course of four semesters of a transformed junior-level Electricity and Magnetism course. Included are homework questions, concept tests, and information about common student difficulties in the topic and ways to address these difficulties. This material was developed as part of a education research-based course transformation for junior level E&M. All of the resources developed for this course are available, sorted by individual topic and type, at http://www.compadre.org/psrc/items/Relations.cfm?ID=7891.
Aristarchus's <em>On the Sizes and Distances of the Sun and the Moonem>: Greek and Arabic Texts
In the 1920s, T. L. Heath pointed out that historians of mathematics have "given too little attention to Aristarchus". This is still true today. The Greek text of Aristarchus's On the Sizes and Distances of the Sun and the Moonem> has received little attention; the Arabic editions virtually none. Much of what this text has to tell us about ancient and medieval mathematics and the mathematical sciences has gone unnoticed. It should be taken as an important source for our understanding of the mathematical sciences of the early Hellenistic period.
Berggren, J. L.; Sidoli, N.
Efeitos da suplementańŃo aguda de aspartato de arginina na fadiga muscular em voluntßrios treinados
RESUMO A atividade fĒsica influi em mecanismos especĒficos responsß- veis pela reduńŃo da produńŃo de forńa e conseq³entemente Ó fadiga. A preocupańŃo em melhorar o desempenho fĒsico tem sido propostos; observamos que estudos dŃo atenńŃo para reduzir ac·- mulos dos metab¾litos que diminuem a fadiga durante o exercĒcio fĒsico intenso, usando aminoßcidos conhecidos por induzir mudan- ńas metab¾licas, entre eles
Ricardo Pombo Sales; Carlos Eduardo Cķsar Minķ; Andrķia Dell· Franco; ╔rika Lima Rodrigues; Renato de Souza e Silva; Josķ Carlos Cogo; Rodrigo A. B. Lopes-Martins; Rodrigo Lazo Osorio; Wellington Ribeiro
On the EM Algorithm and Bootstrap Approach Combination for Improving Satellite Image Fusion
This paper discusses EM algorithm and Bootstrap approach combination applied for the improvement of the satellite image fusion process. This novel satellite image fusion method based on estimation theory EM algorithm and reinforced by Bootstrap approach was successfully implemented and tested. The sensor images are firstly split by a Bayesian segmentation method to determine a joint region map for the
Tijani Delleji; Mourad Zribi; Ahmed Ben
A reduńŃo dos nĒveis de cortisol sanguĒneo atravķs da tķcnica de relaxamento progressivo em nadadores
Reduction of blood cortisol levels through the progres- sive relaxation technique in swimmers Objetivo: Analisar os efeitos da tķcnica de relaxamento progressivo na reduńŃo\\/controle dos nĒveis de cortisol san- guĒneo em nadadores durante determinado perĒodo de trei- namentos. Metodologia: Nadadores de ambos os sexos (n = 23) foram divididos em dois grupos: experimental - GE (n = 11), submetido a
MaurĒcio Gattßs; Bara Filho; Luiz Carlos ScipiŃo Ribeiro; Renato Miranda; M¶nica Tavares Teixeira
Method for evaluating compatibility of commercial electromagnetic (EM) microsensor tracking systems with surgical and imaging tables
Electromagnetic (EM) tracking systems have been successfully used for Surgical Navigation in ENT, cranial, and spine applications for several years. Catheter sized micro EM sensors have also been used in tightly controlled cardiac mapping and pulmonary applications. EM systems have the benefit over optical navigation systems of not requiring a line-of-sight between devices. Ferrous metals or conductive materials that are transient within the EM working volume may impact tracking performance. Effective methods for detecting and reporting EM field distortions are generally well known. Distortion compensation can be achieved for objects that have a static spatial relationship to a tracking sensor. New commercially available micro EM tracking systems offer opportunities for expanded image-guided navigation procedures. It is important to know and understand how well these systems perform with different surgical tables and ancillary equipment. By their design and intended use, micro EM sensors will be located at the distal tip of tracked devices and therefore be in closer proximity to the tables. Our goal was to define a simple and portable process that could be used to estimate the EM tracker accuracy, and to vet a large number of popular general surgery and imaging tables that are used in the United States and abroad.
Nafis, Christopher; Jensen, Vern; von Jako, Ron
Presenńa de dentes permanentes irrompidos em escolares da regiŃo metropolitana de Porto Alegre
RESUMO Foi realizada uma pesquisa de campo em duas escolas da rede p·blica estadual de Porto Alegre, com a finalidade de verificar a presenńa de dentes permanentes irrompidos em crian- ńas com faixa etßria entre seis a dez anos. Foram examinadas 327 crianńas, considerando as varißveis de idade, sexo e rańa. NŃo foi observada diferenńa significativa para a ķpoca de
Karine Squeff; Guilherme Pessoa Cerveira; Luciane Quadrado Closs; Jose Ant¶nio Bosio
PrevalĻncia de sobrepeso\\/obesidade em crianńas e adolescentes com constipańŃo cr¶nica funcional
RESUmO Objetivo: Avaliar a prevalĻncia do sobrepeso\\/obesidade em um grupo de crianńas com constipańŃo cr¶nica funcional. Mķtodos: Estudo retrospectivo com 257 crianńas de dois a 15 anos com constipańŃo cr¶nica funcional diag- nosticada segundo critķrios de Roma II, atendidas con- secutivamente em clĒnica tercißria de gastroenterologia pedißtrica. Informań§es demogrßficas, clĒnicas, diagn¾s - ticas e antropomķtricas foram obtidas de prontußrios. O
Francisca Teresa V. Faleiros; Cristiane Camargo Omae; Cristiane Yoshie Nakazawa; Mary de Assis Carvalho; Nilton Carlos Machado
CompetĻncia social e empatia: um estudo sobre resiliĻncia com crianńas em situańŃo de pobreza
Social competence and empathy: Study about resilience with children in poverty Resumo O objetivo desse estudo foi avaliar a competĻncia social e a empatia em crianńas escolares que vivem em situańŃo de po- breza. Participaram da pesquisa 100 crianńas, de ambos os sexos, com idades entre seis e nove anos. Os instrumentos utilizados foram o Teste das Hist¾rias Incompletas (THI)
Alessandra Marques Cecconello; SĒlvia Helena Koller
2.5D EM modeling in TIV conductive media Torgeir Wiik
2.5D EM modeling in TIV conductive media Torgeir Wiik , Bj├Ėrn Ursin and Ketil Hokstad, Norwegian domain EM model- ing in conductive media, i.e. in media which are assumed invariant in one direction. Further, we consider media which are transversely isotropic in the vertical direction 1 #12;(TIV), thus
Ursin, Bj├Ėrn
Uterus Image Segmentation Using Multi-feature EM Algorithm Based on Gabor Filter
In this work the image is segmented effectively based on texture feature by reducing the noise. For effective image segmentation Expectation-Maximization (EM) algorithm based on Gabor filter is used. The EM algorithm is applied on 2D Ultrasonic image of uterus and tested. The Gabor function has been recognized by its multiresolution properties and the precision of locating the texture features
S. Malarkhodi; R. S. D. W. Banu
UMA AN┴LISE DO CUSTO DE VIAGEM PARA A PRAIA DA AVENIDA EM MACEIė
A cidade de Macei¾ em Alagoas constitui uma cidade litorŌnea da RegiŃo Nordeste do Brasil dotada de beleza natural tais como praias e lagoas, as quais constituem atrativos para o turismo tanto nacional como internacional. Todavia, nesta o crescimento do setor turĒstico tem sido afetado pela poluińŃo dos recursos ambientais, mais especificamente o despejo do esgoto em praias e lagoas.
Eliane Aparecida Pereira De Abreu; Agnaldo Gomes da Silva; Gilberto Gomes Da Silva Junior; Rebecca Suzannah Nascimento De Melo
BWR loss-of-coolant accident analysis capability of the WRAP-EM system
The modular computational system known as the Water Reactor Analysis Package (WRAP) has been extended to provide the computational tools required to perform a complete analysis of LOCAs in BWRs. The new system is known as the WRAP-EM (Evaluation Model) system and will be used by NRC in interpreting and evaluating reactor vendor EM methods and computed results. The system
M. R. Buckner; R. R. Beckmeyer; M. V. Gregory; R. L. Reed; W. G. Winn
Potential cauchy-poisson waves generated by submarine eruptions of kick 'em Jenny volcano
Kick 'em Jenny is the only known currently active submarine volcano in the Lesser Antilles. The volcano has erupted at least 10 times since first being discovered in 1939 and the summit has shoaled from a depth of ~232 m in 1962 to its present-day depth of ~150 m. Kick 'em Jenny is located in a province of explosive volcanism,
M. S. Smith; J. B. Shepherd
Efeito da vitamina C no ganho de peso e em parŌmetros hematol¾gicos de tambaqui
Resumo - O objetivo deste trabalho foi avaliar o efeito da suplementańŃo dietßria com ßcido L-asc¾rbico (vitamina C) no ganho de peso e em parŌmetros hematol¾gicos de juvenis de tambaqui, Colossoma macropomum. Ap¾s dez semanas, em que foram alimentados com dietas contendo 0, 100 e 500 mg de ßcido L-asc¾rbico por kg de rańŃo, os peixes foram capturados e imediatamente
Edsandra Campos Chagas; Adalberto LuĒs Val
ISOLAMENTO E IDENTIFICAŪ├O DE BACT╔RIAS CANDIDATAS A PROBIėTICOS EM CAMARšES DA ESP╔CIE LITOPENAEUS VANNAMEI
RESUMO O objetivo desse trabalho foi isolar e identificar bactķrias candidatas a probi¾ticos do trato intestinal de camar§es da espķcie Litopenaeus vannamei, em diferentes fases de desenvolvimento. Foram utilizados camar§es nas fases de recria e inicial (p¾s-larva) e de crescimento (juvenil), os quais eram adaptados Ó ßgua doce da Fazenda BAHIA PESCA, especializada em aq³icultura, localizada no municĒpio de Santo
BSSDATA - um programa otimizado para filtragem de dados em radioastronomia solar
A partir de 1998, entrou em operańŃo regular no INPE, em SŃo Josķ dos Campos, o Brazilian Solar Spectroscope (BSS). O BSS ķ dedicado Ós observań§es de explos§es solares decimķtricas com alta resoluńŃo temporal e espectral, com a principal finalidade de investigar fen¶menos associados com a liberańŃo de energia dos \\
A. R. F. Martinon; H. S. Sawant; F. C. R. Fernandes; S. Stephany; A. J. Preto; K. M. Dobrowolski
Jur├Łdicas Contratuais e Responsabilidade Civil; (iv) Rela├¦├Ąes Jur├Łdicas Familiares e Sucess├Żo; (v) Ensino1 N├?CLEO DE ESTUDOS EM DIREITO CIVIL CONSTITUCIONAL PROJETO DE PESQUISA VIRADA DE COP├?RNICO ESTUDOS EM DIREITO CIVIL CONSTITUCIONAL ┬Ł PROJETO DE PESQUISA VIRADA DE COP├?RNICO, observadas as seguintes
Paran├Ī, Universidade Federal do
Anxiety levels in EMS providers: Effects of violence and shift schedules
We tried to measure anxiety levels in emergency medical service (EMS) providers to determine the effects of (1) having had a violent encounter during a shift and (2) different shift schedules, conducting a prospective observational study over 3 months in an urban EMS system setting. A convenience sample of 23 EMTs and 40 EMT-Ps was observed. Anxiety levels were measured
Elisabeth Fowlie Mock; Keith D Wrenn; Seth W Wright; T. Chadwick Eustis; Corey M Slovis
PERFIL DOS ACIDENTES POR LIQUIDOS AQUECIDOS EM CRIANŪAS ATENDIDAS EM CENTRO DE REFER╩NCIA DE FORTALEZA The Profile of Accidents by Hot Liquids in Children Attended at a Reference Center in Fortaleza
RESUMO As queimaduras sŃo acidentes frequentes e representam a segunda causa de morte na infŌncia. Este trabalho objetivou identificar o perfil dos acidentes em crianńas queimadas por lĒquidos aquecidos. Estudo descritivo, realizado com 62 pais de crianńas internadas em um Centro de Tratamento para Queimados, em Fortaleza, Cearß, no perĒodo de janeiro a junho de 2002. As varißveis estudadas foram:
Rita Neuma; Dantas Cavalcante; ╔rika Porto Xavier; Luiza Jane; Eyre de Souza
Cryo-EM modeling by the molecular dynamics flexible fitting method
The increasing power and popularity of cryo-electron (cryo-EM) microscopy in structural biology brought about the development of so-called hybrid methods, which permit the interpretation of cryo-EM density maps beyond their nominal resolution in terms of atomic models. The Cryo-EM Modeling Challenge 2010 is the first community effort to bring together developers of hybrid methods as well as cryo-EM experimentalists. Participating in the challenge, the molecular dynamics flexible fitting (MDFF) method was applied to a number of cryo-EM density maps. The results are described here with special emphasis on the use of symmetry-based restraints to improve the quality of atomic models derived from density maps of symmetric complexes; on a comparison of the stereochemical quality of atomic models resulting from different hybrid methods; and on application of MDFF to electron crystallography data. PMID:22696404
Chan, Kwok-Yan; Trabuco, Leonardo G.; Schreiner, Eduard; Schulten, Klaus
EMS1 gene expression in primary breast cancer: relationship to cyclin D1 and oestrogen receptor expression and patient survival
The EMS1 and CCND1 genes at chromosome 11q13 are amplified in about 15% of primary breast cancers but appear to confer different phenotypes in ER positive and ER negative tumours. Since there are no published data on EMS1 expression in large series of breast cancers we examined the relationship of EMS1 expression with EMS1 gene copy number and expression of
Rina Hui; Jonathon R Ball; R Douglas Macmillan; Frances S Kenny; Owen WJ Prall; Douglas H Campbell; Ann L Cornish; Richard A McClelland; Roger J Daly; John F Forbes; Roger W Blamey; Elizabeth A Musgrove; John FR Robertson; Robert I Nicholson; Robert L Sutherland
A Gentle Tutorial of the EM Algorithm and its Application to Parameter Estimation for Gaussian Mixture and Hidden Markov Models
We describe the maximum-likelihood parameter estimation problem and how the Expectation- Maximization (EM) algorithm can be used for its solution. We first describe the abstract form of the EM algorithm as it is often given in the literature. We then develop the EM pa- rameter estimation procedure for two applications: 1) finding the parameters of a mixture of Gaussian densities,
Jeff A. Bilmes
Efeitos da monensina sobre a fermentańŃo e sensibilidade de bactķrias ruminais de bovinos sob dietas ricas em volumoso ou concentrado
RESUMO - Objetivou-se avaliar os efeitos da monensina sobre as mudanńas nos padr§es de fermentańŃo e resistĻncia Ó perda do potßssio intracelular das bactķrias ruminais provenientes de quatro bovinos recebendo dietas ricas em volumoso ou concentrado. As bactķrias obtidas por centrifugańŃo diferencial foram resuspensas em um meio pobre em potßssio, no qual foi medida a perda do p otßssio intracelular,
Rogķrio de Paula Lana; James B. Russell
We present a spectral analysis of the Far Ultraviolet Spectroscopic Explorer (FUSE) spectra of the eclipsing double-line spectroscopic binary EM Cygni (EM Cyg), a Z Cam DN system. The FUSE spectrum, obtained in quiescence, consists of four individual exposures (orbits): two exposures, at orbital phases {phi} {approx} 0.65 and {phi} {approx} 0.90, have a lower flux; and two exposures, at orbital phases {phi} = 0.15 and 0.45, have a relatively higher flux. The change of flux level as a function of the orbital phase is consistent with the stream material (flowing over and below the disk from the hot spot region to smaller radii) partially masking the white dwarf. We carry out a spectral analysis of the FUSE data, obtained at phase 0.45 (when the flux is maximal), using synthetic spectra generated with the codes TLUSTY and SYNSPEC. Using a single white dwarf spectral component, we obtain a white dwarf temperature of 40, 000 K {+-} 1000 K, rotating at 100 km s{sup -1}. The white dwarf, or conceivably, the material overflowing the disk rim, shows suprasolar abundances of silicon, sulphur, and possibly nitrogen. Using a white dwarf+disk composite model, we obtain that the white dwarf temperature could be even as high as 50,000 K, contributing more than 90% of the FUV flux, and the disk contributing less than 10% must have a mass accretion rate reaching 10{sup -10} M{sub sun} yr{sup -1}. The single white dwarf model fits the absorption lines better than the white dwarf+disk model, but the white dwarf+disk model fits better the continuum in the shorter wavelengths. In both cases, however, we obtain that the white dwarf temperature is much higher than previously estimated. We emphasize the importance of modeling the spectra of EM Cyg around phase {phi} < 0.5, when the white dwarf and disk are facing the observer, and we suggest that the discrepancy between the present analysis and previous spectral analysis might be due to the occulting effect of the stream veiling the white dwarf and disk.
Godon, Patrick; Sion, Edward M. [Department of Astronomy and Astrophysics, Villanova University, Villanova, PA 19085 (United States); Barrett, Paul E. [United States Naval Observatory, Washington, DC 20392 (United States); Linnell, Albert P. [Department of Astronomy, University of Washington, Seattle, WA 98195 (United States)], E-mail: firstname.lastname@example.com, E-mail: email@example.com, E-mail: email@example.com, E-mail: email@example.com, E-mail: firstname.lastname@example.com
Dolasetron Injection
... Be sure to mention any of the following: atenolol (Tenormin, in Tenoretic), cimetidine; diuretics ('water pills'); medications ... pressure; medications for irregular heart beat such as atenolol (Tenormin, in Tenoretic), flecainide (Tambocor),quinidine (Quinidex, Quinaglute, ...
The EM SSAB Annual Work Plan Process: Focusing Board Efforts and Resources - 13667
One of the most daunting tasks for any new member of a local board of the Environmental Management Site Specific Advisory Board (EM SSAB) is to try to understand the scope of the clean-up activities going on at the site. In most cases, there are at least two or three major cleanup activities in progress as well as monitoring of past projects. When planning for future projects is added to the mix, the list of projects can be long. With the clean-up activities involving all major environmental media - air, water, soils, and groundwater, new EM SSAB members can find themselves totally overwhelmed and ineffective. Helping new members get over this initial hurdle is a major objective of EM and all local boards of the EM SSAB. Even as members start to understand the size and scope of the projects at a site, they can still be frustrated at the length of time it takes to see results and get projects completed. Many project and clean-up timelines for most of the sites go beyond 10 years, so it's not unusual for an EM SSAB member to see the completion of only 1 or 2 projects over the course of their 6-year term on the board. This paper explores the annual work planning process of the EM SSAB local boards, one tool that can be used to educate EM SSAB members into seeing the broader picture for the site. EM SSAB local work plans divide the site into projects focused on a specific environmental issue or media such as groundwater and/or waste disposal options. Projects are further broken down into smaller segments by highlighting major milestones. Using these metrics, local boards of the EM SSAB can start to quantify the effectiveness of the project in achieving the ultimate goal of site clean-up. These metrics can also trigger board advice and recommendations for EM. At the beginning of each fiscal year, the EM SSAB work plan provides a road map with quantifiable checkpoints for activities throughout the year. When the work plans are integrated with site-specific, enforceable regulatory milestones, they can provide a comprehensive work plan for not only the board, but also regulators, site contractors, and DOE. Because the work plans are reviewed and approved by DOE, they carry some weight in holding local boards of the EM SSAB accountable. This structure provides the basis for local boards to achieve their primary function, to provide DOE with information, advice, and recommendations concerning issues affecting the EM program at the site. (authors)
Young, Ralph [Paducah Citizens Advisory Board (United States)] [Paducah Citizens Advisory Board (United States)
Integrated EM & Thermal Simulations with Upgraded VORPAL Software
Nuclear physics accelerators are powered by microwaves which must travel in waveguides between room-temperature sources and the cryogenic accelerator structures. The ohmic heat load from the microwaves is affected by the temperature-dependent surface resistance and in turn affects the cryogenic thermal conduction problem. Integrated EM & thermal analysis of this difficult non-linear problem is now possible with the VORPAL finite-difference time-domain simulation tool. We highlight thermal benchmarking work with a complex HOM feed-through geometry, done in collaboration with researchers at the Thomas Jefferson National Accelerator Laboratory, and discuss upcoming design studies with this emerging tool. This work is part of an effort to generalize the VORPAL framework to include generalized PDE capabilities, for wider multi-physics capabilities in the accelerator, vacuum electronics, plasma processing and fusion R&D fields, and we will also discuss user interface and algorithmic upgrades which facilitate this emerging multiphysics capability.
D.N. Smithe, D. Karipides, P. Stoltz, G. Cheng, H. Wang
This Working Group (WG) focused on EM Structure-Based Accelerators, which covers a broad area of mechanisms and experiments. Topics covered included dielectric wakefield accelerators (DWA), photonic bandgap accelerators (PBGA), inverse free electron lasers (IFEL), vacuum laser accelerators (VLA), other novel schemes, and supporting analysis and modeling. In addition, this WG was tasked at the Workshop with developing conceptual (strawman) designs for a 1-GeV accelerator system based upon any of the experimentally-proven approaches covered in this WG. Two strawmen designs were developed based upon IFELs and DWAs. The presentations given and strawmen designs indicate great progress has been made in many areas. Proof-of-principle experiments will occur shortly in PBGA and VLA. Other well-proven devices, such as IFELs, are becoming accepted as "workhorse" providers of microbunches.
Kimura, W. D.; Lidia, S. M.
EM-based measurement fusion for HRR radar centroid processing
This paper develops a new algorithm for high range resolution (HRR) radar centroid processing for scenarios where there are closely spaced objects. For range distributed targets with multiple discrete scatterers, HRR radars will receive detections across multiple range bins. When the resolution is very high, and the target has significant extent, then it is likely that the detections will not occur in adjacent bins. For target tracking purposes, the multiple detections must be grouped and fused to create a single object report and a range centroid estimate is computed since the detections are range distributed. With discrete scatterer separated by multiple range bins, then when closely spaced objects are present there is uncertainty about which detections should be grouped together for fusion. This paper applies the EM algorithm to form a recursive measurement fusion algorithm that segments the data into object clusters while simultaneously forming a range centroid estimate with refined bearing and elevation estimates.
Slocumb, Benjamin J.; Blair, W. Dale
SEI: Junior E&M I Course Materials - Homework
This homework question collection was constructed over the course of four semesters of a transformed junior-level Electricity and Magnetism course on electro- and magneto-statics. Many questions are related to textbook problems, but with added elements of explanation, sense-making, estimation or approximation, real-world connections, and multiple-representations. Not all these homework questions were used in the course design project. Some problems used include detailed instructor notes, including statistics on student performance on each homework problem assigned. The homework solutions are only available to instructors by writing the authors, firstname.lastname@example.com This material was developed as part of a education research-based course transformation for junior level E&M. All of the resources developed for this course are available, sorted by individual topic and type, at http://www.compadre.org/psrc/items/Relations.cfm?ID=7891.
SEI: Junior E&M I Course Materials - Tutorials
This collection of tutorials and tutorial pre-tests was constructed for a transformed junior-level Electricity and Magnetism course. These tutorials are weekly student sessions, modeled after research-validated curricula developed at the University of Washington. Using these materials in study/recitation sections, students work in small groups with the instructor as a learning coach. The materials are designed to target known student difficulties, to elicit and develop conceptual understanding and math/physics connections. They also help faculty listen to student reasoning, get a clearer sense of student ideas, and determine where they are struggling. This material was developed as part of a education research-based course transformation for junior level E&M. All of the resources developed for this course are available, sorted by individual topic and type, at http://www.compadre.org/psrc/items/Relations.cfm?ID=7891.
Pollock, Steven J.; Chasteen, Stephanie V.; Kinney, Edward; Dubson, Michael
EM modeling of RF drive in DTL tank 4
A 3-D MicroWave Studio model for the RF drive in the LANSCE DTL tank 4 has been built. Both eigensolver and time-domain modeling are used to evaluate maximal fields in the drive module and RF coupling. The LANSCE DTL tank 4 has recently been experiencing RF problems, which may or may not be related to its replaced RF coupler. This situation stimulated a request by Dan Rees to provide EM modeling of the RF drive in the DTL tank 4 (T4). Jim O'Hara provided a CAD model that was imported into the CST Microwave Studio (MWS) and after some modifications became a part of a simplified MWS model of the T4 RF drive. This technical note describes the model and presents simulation results.
Kurennoy, Sergey S. [Los Alamos National Laboratory
Speech articulator measurements using low power EM-wave sensors
Very low power electromagnetic (EM) wave sensors are being used to measure speech articulator motions as speech is produced. Glottal tissue oscillations, jaw, tongue, soft palate, and other organs have been measured. Previously, microwave imaging (e.g., using radar sensors) appears not to have been considered for such monitoring. Glottal tissue movements detected by radar sensors correlate well with those obtained by established laboratory techniques, and have been used to estimate a voiced excitation function for speech processing applications. The noninvasive access, coupled with the small size, low power, and high resolution of these new sensors, permit promising research and development applications in speech production, communication disorders, speech recognition and related topics. {copyright} {ital 1998 Acoustical Society of America.}
Holzrichter, J.F.; Burnett, G.C.; Ng, L.C. [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States)] [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States); Lea, W.A. [Speech Science Institute, P.O. Box 240428, Apple Valley, Minnesota 55124 (United States)] [Speech Science Institute, P.O. Box 240428, Apple Valley, Minnesota 55124 (United States)
EM Properties of Magnetic Minerals at RADAR Frequencies
Previous missions to Mars have revealed that Mars surface is magnetic at DC frequency. Does this highly magnetic surface layer attenuate RADAR energy as it does in certain locations on Earth? It has been suggested that the active magnetic mineral on Mars is titanomaghemite and/or titanomagnetite. When titanium is incorporated into a maghemite or magnetite crystal, the Curie temperature can be significantly reduced. Mars has a wide range of daily temperature fluctuations (303K - 143K), which could allow for daily passes through the Curie temperature. Hence, the global dust layer on Mars could experience widely varying magnetic properties as a function of temperature, more specifically being ferromagnetic at night and paramagnetic during the day. Measurements of EM properties of magnetic minerals were made versus frequency and temperature (300K- 180K). Magnetic minerals and Martian analog samples were gathered from a number of different locations on Earth.
Stillman, D. E.; Olhoeft, G. R.
This Working Group (WG) focused on EM Structure-Based Accelerators, which covers a broad area of mechanisms and experiments. Topics covered included dielectric wakefield accelerators (DWA), photonic bandgap accelerators (PBGA), inverse free electron lasers (IFEL), vacuum laser accelerators (VLA), other novel schemes, and supporting analysis and modeling. In addition, this WG was tasked at the Workshop with developing conceptual (strawman) designs for a 1-GeV accelerator system based upon any of the experimentally-proven approaches covered in this WG. Two strawmen designs were developed based upon IFELs and DWAs. The presentations given and strawmen designs indicate great progress has been made in many areas. Proof-of-principle experiments will occur shortly in PBGA and VLA. Other well-proven devices, such as IFELs, are becoming accepted as 'workhorse' providers of microbunches.
Kimura, W.D. [STI Optronics, Inc., 2755 Northup Way, Bellevue, WA 98004 (United States); Lidia, S.M. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States)
QCD effective potential with strong U(1)em magnetic fields
We derive the analytic expression for the one-loop SU(Nc) QCD effective potential including Nf flavor quarks which nonlinearly interact with the chromomagnetic background field and the external U(1)em magnetic field. After the renormalization of couplings and fields, we obtain the correct one-loop ? functions of both QCD and QED, and the resulting effective potential satisfies the renormalization group equation. We investigate the effect of the magnetic field on the QCD vacuum by using the effective potential, in particular for the color SU(3) case with the three flavors (u ,d,s). Our result shows that the chromomagnetic field prefers to be parallel to the external magnetic field. Furthermore, quark loop contributions to the effective potential with the magnetic field enhance gluonic contributions, and then the chromomagnetic condensate increases with an increasing magnetic field. This result supports the recent observed gluonic magnetic catalysis at zero-temperature in lattice QCD.
Ozaki, Sho
Benchmarking a derivative-free minimax optimizer for EM design
The paper presents a model-based derivative-free minimax optimizer and a benchmarking methodology. The optimizer is dedicated to such simulation-based design scenarios, when a single simulation is time-consuming and not very accurate, and so when fast improvement of design is expected rather then high accuracy optimization. A benchmarking methodology is formulated to compare efficiency of optimizers in such scenarios. A set of electromagnetic (EM) designs, for which a design simulation involves solution of very large partial differential equations, is used to exemplify the methodology. Presented results demonstrate how accuracy requirements and computational budget change ranking of optimizers. The proposed optimizer is shown to provide competetively rapid and reliable initial design improvement for modest 5-10% tolerance, but for higher accuracy demands and larger computational budget other solvers become more competitive.
Opalski, Leszek J.
TrakEM2 software for neural circuit reconstruction.
A key challenge in neuroscience is the expeditious reconstruction of neuronal circuits. For model systems such as Drosophila and C. elegans, the limiting step is no longer the acquisition of imagery but the extraction of the circuit from images. For this purpose, we designed a software application, TrakEM2, that addresses the systematic reconstruction of neuronal circuits from large electron microscopical and optical image volumes. We address the challenges of image volume composition from individual, deformed images; of the reconstruction of neuronal arbors and annotation of synapses with fast manual and semi-automatic methods; and the management of large collections of both images and annotations. The output is a neural circuit of 3d arbors and synapses, encoded in NeuroML and other formats, ready for analysis. PMID:22723842
Cardona, Albert; Saalfeld, Stephan; Schindelin, Johannes; Arganda-Carreras, Ignacio; Preibisch, Stephan; Longair, Mark; Tomancak, Pavel; Hartenstein, Volker; Douglas, Rodney J
DOE-EM privatization and the 2006 Plan: Principles for procurement policies and risk management
The Department of Energy`s Office of Environmental Remediation and Waste Management (EM) has recently set in place programs to restructure the strategic planning mechanism that will drive its clean-up schedule, The 2006 Plan, and to create a new set of business relationships with private contractors that will reduce costs--privatization. Taken together, the 2006 Plan and privatization will challenge EM to create new business practices to recast its risk management policies to support these initiatives while ensuring that its responsibilities toward the environment, human health, and worker safety (ES and H) are maintained. This paper argues that the 2006 Plan has transformed EM`s traditional, bottoms-up approach based on technical dictates to a top-down approach based on management goals--a transformation from an engineering problem to an economic problem. The 2006 Plan evolved from EM`s Ten-Year Plan, and seeks to convert the largely open-ended planning approach previously undertaken by EM to a plan bounded by time and dollars. The plan emphasizes making tradeoffs and choosing activities that deliver the most clean-up for the dollar. It also recognizes that each major player--stakeholders, DOE, OMB and Congress--has distinct interests that must be resolved if the process is to succeed. This, in turn, has created the need for a corresponding transformation in risk management practices from compliance-driven to benefit/cost-driven.
Bjornstad, D.J.; Jones, D.W.; Duemmer, C.L.
Linear array implementation of the EM algorithm for PET image reconstruction
The PET image reconstruction based on the EM algorithm has several attractive advantages over the conventional convolution back projection algorithms. However, the PET image reconstruction based on the EM algorithm is computationally burdensome for today`s single processor systems. In addition, a large memory is required for the storage of the image, projection data, and the probability matrix. Since the computations are easily divided into tasks executable in parallel, multiprocessor configurations are the ideal choice for fast execution of the EM algorithms. In tis study, the authors attempt to overcome these two problems by parallelizing the EM algorithm on a multiprocessor systems. The parallel EM algorithm on a linear array topology using the commercially available fast floating point digital signal processor (DSP) chips as the processing elements (PE`s) has been implemented. The performance of the EM algorithm on a 386/387 machine, IBM 6000 RISC workstation, and on the linear array system is discussed and compared. The results show that the computational speed performance of a linear array using 8 DSP chips as PE`s executing the EM image reconstruction algorithm is about 15.5 times better than that of the IBM 6000 RISC workstation. The novelty of the scheme is its simplicity. The linear array topology is expandable with a larger number of PE`s. The architecture is not dependant on the DSP chip chosen, and the substitution of the latest DSP chip is straightforward and could yield better speed performance.
Rajan, K.; Patnaik, L.M.; Ramakrishna, J. [Indian Institute of Science, Bangalore (India)] [Indian Institute of Science, Bangalore (India)
Queda dos homic?dios em S?o Paulo, Brasil: uma an?lise descritiva
Objetivo Descrever a evoluńŃo da mortalidade por homicĒdios no MunicĒpio de SŃo Paulo segundo tipo de arma, sexo, rańa ou cor, idade e ßreas de exclusŃo/inclusŃo social entre 1996 e 2008. Mķtodos Estudo ecol¾gico de sķrie temporal. Os dados sobre ¾bitos ocorridos no MunicĒpio foram coletados da base de dados do Programa de Aprimoramento das Informań§es sobre Mortalidade, seguindo a ClassificańŃo Internacional de Doenńas, Dķcima RevisŃo (CID-10). Foram calculadas as taxas de mortalidade por homicĒdio (TMH) para a populańŃo total, por sexo, rańa ou cor, faixa etßria, tipo de arma e ßrea de exclusŃo/inclusŃo social. As TMH foram padronizadas por idade pelo mķtodo direto. Foram calculados os percentuais de variańŃo no perĒodo estudado. Para as ßreas de exclusŃo/inclusŃo social foram calculados os riscos relativos de morte por homicĒdio. Resultados As TMH apresentaram queda de 73,7% entre 2001 e 2008. Foi observada reduńŃo da TMH em todos os grupos analisados, mais pronunciada em homens (?74,5%), jovens de 15 a 24 anos (?78,0%) e moradores de ßreas de exclusŃo social extrema (?79,3%). A reduńŃo ocorreu, sobretudo, nos homicĒdios cometidos com armas de fogo (?74,1%). O risco relativo de morte por homicĒdio nas ßreas de exclusŃo extrema (tendo como referĻncia ßreas com algum grau de exclusŃo social) foi de 2,77 em 1996, 3,9 em 2001 e 2,13 em 2008. Nas ßreas de alta exclusŃo social, o risco relativo foi de 2,07 em 1996 e 1,96 em 2008. Conclus§es Para compreender a reduńŃo dos homicĒdios no MunicĒpio, ķ importante considerar macrodeterminantes que atingem todo o MunicĒpio e todos os subgrupos populacionais e microdeterminantes que atuam localmente, influenciando de forma diferenciada os homicĒdios com armas de fogo e os homicĒdios na populańŃo jovem, no sexo masculino e em residentes em ßreas de alta exclusŃo social. PMID:21390415
Peres, Maria Fernanda Tourinho; Vicentin, Diego; Nery, Marcelo Batista; de Lima, Renato Sergio; de Souza, Edinilsa Ramos; Cerda, Magdalena; Cardia, Nancy; Adorno, e Sergio
Ondas de choque em jatos de quasares e objetos BL Lacertae
Este trabalho ķ parte de um projeto que vem sendo realizado hß dois anos no CRAAM, cujos objetivos principais sŃo analisar e aplicar um modelo generalizado de ondas de choque em jatos relativĒsticos de plasma, presentes em quasares e objetos BL Lacertae, para explicar a variabilidade observada nestes objetos. O mķtodo consiste em uma decomposińŃo de curvas de luz em sķries de explos§es similares, em vßrias freq³Ļncias, baseando-se em uma evoluńŃo espectro-temporal mķdia das explos§es. A partir da evoluńŃo mķdia, um ajuste de cada explosŃo ķ feito com base em equań§es empĒricas, modificando-se apenas parŌmetros especĒficos de cada explosŃo. Inicialmente o modelo foi aplicado ajustando-se as curvas de luz a explos§es delineadas por uma evoluńŃo do choque em trĻs estßgios, segundo a predominŌncia do processo de emissŃo: sĒncrotron, Compton e adiabßtico. Entretanto, nesta nova fase de projeto, visando uma parametrizańŃo mais concisa, uma otimizańŃo do algoritmo de ajuste e uma convergĻncia mais rßpida, a formulańŃo para cada evento foi assumida com uma evoluńŃo em apenas dois estßgios: subida e descida. Isto possibilitou uma ¾tima delineańŃo das curvas de luz das fontes OV236, OJ287, 3C273 e BL Lac, entre 1980 e 2000, nas freq³Ļncias 4.8, 8.0, 14.5 e 22 GHz, utilizando-se dados do Observat¾rio da Universidade de Michigan, do Observat¾rio do Itapetinga (Atibaia SP) e do Observat¾rio Metsõhovi. Como conclus§es importantes, verificou-se que: os parŌmetros ajustados descrevem o comportamento do jato; os valores do Ēndice que descreve a expansŃo do jato sugerem que o mesmo se expande de uma forma nŃo-c¶nica; o campo magnķtico ķ turbulento atrßs da frente de choque; e as peculiaridades das explos§es sŃo devidas Ó influĻncia de grandezas tais como o coeficiente da distribuińŃo espectral de energia dos elķtrons, a intensidade de campo magnķtico e o fator de feixe Doppler, no inĒcio do choque.
Melo, F. E.; Botti, L. C. L.
EM Wake-Sleep email@example.com
┬ŁEM Wake-Sleep ┬Ł 21 2-1 email@example.com 1 (Latent Variable) 2 2.1 -5 -2.5 0 2.5 5 x+1), p(x; )) t+1 6 #12;3.3 Wake-Sleep EM G. Hinton EM Wake-Sleep [6] Helmholtz Helmholtz Helmholtz Helmholtz 6 M D q(y|x; ) p(x, y; ) 2 Wake-Sleep t+1 D M KL(q ,p )KL(p ,q ) t+1 t () ()() () t 7: Wake
Ikeda, Shiro
User's guide for the PWR LOCA analysis capability of the WRAP-EM system
The Water Reactor Analysis Package (WRAP) has been expanded to provide the capability to analyze loss-of-coolant accidents (LOCAs) in both pressurized water reactors (PWRs) and boiling water reactors (BWRs) by using evaluation models (EMs). The input specifications for modules in the WRAP-EM system are presented in this document along with the JOSHUA input templates. This document, along with the WRAP user's guide, provides a step-by-step procedure for setting up a PWR data base for the WRAP-EM system. 12 refs.
Beranek, F; Gregory, M V
EMS Provider Assessment of Vehicle Damage Compared to a Professional Crash Reconstructionist
Objective To determine the accuracy of EMS provider assessments of motor vehicle damage, when compared to measurements made by a professional crash reconstructionist. Methods EMS providers caring for adult patients injured during a motor vehicle crash and transported to the regional trauma center in a midsized community were interviewed upon ED arrival. The interview collected provider estimates of crash mechanism of injury. For crashes that met a preset severity threshold, the vehicleÆs owner was asked to consent to having a crash reconstructionist assess their vehicle. The assessment included measuring intrusion and external auto deformity. Vehicle damage was used to calculate change in velocity. Paired t-test and correlation were used to compare EMS estimates and investigator derived values. Results 91 vehicles were enrolled; of these 58 were inspected and 33 were excluded because the vehicle was not accessible. 6 vehicles had multiple patients. Therefore, a total of 68 EMS estimates were compared to the inspection findings. Patients were 46% male, 28% admitted to hospital, and 1% died. Mean EMS estimated deformity was 18ö and mean measured was 14ö. Mean EMS estimated intrusion was 5ö and mean measured was 4ö. EMS providers and the reconstructionist had 67% agreement for determination of external auto deformity (kappa 0.26), and 88% agreement for determination of intrusion (kappa 0.27) when the 1999 Field Triage Decision Scheme Criteria were applied. Mean EMS estimated speed prior to the crash was 48 mph▒13 and mean reconstructionist estimated change in velocity was 18 mph▒12 (correlation -0.45). EMS determined that 19 vehicles had rolled over while the investigator identified 18 (kappa 0.96). In 55 cases EMS and the investigator agreed on seatbelt use, for the remaining 13 cases there was disagreement (5) or the investigator was unable to make a determination (8) (kappa 0.40). Conclusions This study found that EMS providers are good at estimating rollover. Vehicle intrusion, deformity, and seatbelt use appear to be more difficult to estimate with only fair agreement with the crash reconstructionist. As expected, the EMS provider estimated speed prior to the crash does not appear to be a reasonable proxy for change in velocity. PMID:21815732
Lerner, E. Brooke; Cushman, Jeremy T.; Blatt, Alan; Lawrence, Richard; Shah, Manish N.; Swor, Robert; Brasel, Karen; Jurkovich, Gregory J.
Investigating the source of contaminated plumes downstream of the Alborz Sharghi coal washing plant using EM34 conductivity data, VLF-EM and DC-resistivity geophysical methods
Coal washing factories may create serious environmental problems due to pyrite oxidation and acid mine drainage generation from coal waste piles on nearby land. Infiltration of pyrite oxidation products through the porous materials of the coal waste pile by rainwater cause changes in the conductivity of underground materials and groundwater downstream of the pile. Electromagnetic and electrical methods are effective for investigation and monitoring of the contaminated plumes caused by coal waste piles and tailings impoundments. In order to investigate the environmental impact from a coal waste pile at the Alborz Sharghi coal washing plant, an EM34 ground conductivity meter was used on seven parallel lines in an E-W direction, downstream of the waste pile. Two-dimensional resistivity models obtained by the inversion of EM34 conductivity data identified conductive leachate plumes. In addition, quasi-3D inversion of EM34 data has confirmed the decreasing resistivity at depth due to the contaminated plumes. Comparison between EM34, VLF and DC-resistivity datasets, which were acquired for similar survey lines, agree well in identifying changes in the resistivity trend. The EM34 and DC-resistivity sections have greater similarity and better smoothness rather than those of the VLF model. Two-dimensional inversion models of these methods have shown some contaminated plumes with low resistivity.
Shiraz, Farzin Amirkhani; Ardejani, Faramarz Doulati; Moradzadeh, Ali; Arab-Amiri, Ali Reza
Serodiagnosis of alveolar echinococcosis: detection of antibody against EM18 in patients and rodents.
An international collaborative study on echinococcosis has been carried out for the establishment of a simple means for differential serodiagnosis of alveolar echinococcosis (AE) from other parasitic diseases including cystic echinococcosis (CE). The main candidate epitope is Em18 (previously undescribed epitope of a low molecular weight protein of 18.5 kDa). Evaluation of the usefulness of Em18 is introduced in this review paper. Serum samples showing antibody response against Em18 are exclusively from AE. The predominant IgG subclass recognizing Em18 is IgG4 or IgG1 or IgG4 + IgG1 but never IgG2. There are good correlations between (1) the antibody response against Em18 and the presence of active lesions and (2) the antibody response against Em18 and the Em2-ELISA values. Em18 is, therefore, expected to be reasonably reliable and useful for differentiation of active AE from inactive AE. A new ELISA system using a partially purified Em18 enriched fraction (PP-Em 18/16-ELISA) has been evaluated for serodiagnosis of AE compared with Em2plus-ELISA. A total of 194 serum samples were examined: 127 sera from AE (79) and CE (48) in China where both AE and CE are endemic, 21 sera from CE in Australia where CE only exists, 28 sera from cysticercosis (21), paragonimiasis (5) or sparganasis (2) in Korea where no indigenous AE nor CE exists and 11 normal sera. Antibody levels by PP-Em18/16-ELISA were much higher in AE than in CE and it was also true for commercially available Em2plus-ELISA. Some of CE from China showed exceptionally higher levels of antibody in comparison with those of CE from Australia. It is suggested that these strongly positive cases of CE from China may have been exposed to both species of Echinococcus. Although most of sera from paragonimiasis showed high antibody levels by Emplus-ELISA, they were negative by PP-Em18/16-ELISA. Therefore, PP-Em18/16-ELISA is expected to be more reliable for differentiation of AE from CE and others especially in Asian countries where paragonimiasis is still not rare. Antibody responses in rodents naturally infected with E. multilocularis: Serum samples from the wild vole, Clethrionomys rufocanus bedfordiae, infected with E. multilocularis showed similar antibody responses as in AE patients, whereas those from Norway rats, Rattus norvegicus, showed almost none. The latter rodents were simultaneously infected with Taenia taeniaeformis but showed no antibody response against T. taeniaeformis either. Therefore, we speculate that Norway rats may only be infected with E. multilocularis under some immunosuppressed conditions or genetic unresponsiveness. It is stressed that Em18 is highly specific to E. multilocularis, and antibody response against Em18 is reasonably reliable for differentiation of AE from other helminthic infections by Western blot and ELISA in humans and may be useful for detection of domestic animals contaminated with E. multilocularis in the endemic area. PMID:9656361
Akira, I
MINUTA DE PARECER DA COMISSO INTERNA DE SUPERVISO O Pleno da Comisso Interna de Superviso dos Cargos Tcnico-Administrativos em Educao da
". Neste Of'┐Įcio a pr'┐Įpria reitora em exerc'┐Įcio reconhece que, ap'┐Įs a avalia'┐Į'┐Įo participativa em todos os foi firmado em documento oficial pela pr'┐Įpria reitora em exerc'┐Įcio, deveria ser aberto processo
Simulating Suspended Silt Concentrations in the Ems Estuary, The Netherlands
1 Introduction The Ems Estuary is situated in the North-east Netherlands on the border with Germany. Its area, including the tidal river and excluding the outer delta, is ▒ 500 km2. The area of the outer delta is ▒ 100 km2. The length of the estuary from the inlet to the town of Leer in Germany is approximately 75 km. The mean tidal range varies over years (de Jonge, 1992), but is approximately 2.3 m near the island of Borkum (tidal inlet) and approximately 3.2 m near the town of Emden in Germany. The estuary receives water from the rain-fed River Ems (approximately 115 m3/s on average). A second much smaller freshwater input emanates from the small canalized river Westerwoldsche Aa (12.5 m3/s on average). These discharges vary strongly within and between years. The result of the interaction between freshwater discharge and seawater brought in by the tide is a salinity gradient, the length and position of which is strongly dependent on the water discharge by the rivers. The present morphology of the estuary is the result of natural processes such as tidal currents, wind and wave driven currents and river discharge, resulting in sediment trans-port and sedimentation and erosion patterns. These natural processes are affected by human interferences like maintenance dredging of the navigation channels, land reclamation, building of dikes, etc. The greatest changes in the last 50 years in the physical functioning of the Ems estuary have been the increased sea level and tidal range, the increased amplitude and frequency of storm surge, and greatly increased turbidity and sediment concentrations (particularly near the estuarine turbidity maximum). Much of the changes can be traced directly or indirectly to anthropogenic influence. 2 Aim and approach We studied the hydrodynamics and morphodynamics of the Ems estuary. One of the aims was to gain more insight in the behaviour of the suspended silt concentrations in the estuary and the anthropogenic influence thereon. We applied a beta release of the state-of-the-art Delft3D numerical model for this purpose. The model includes a new sediment transport module published by Van Rijn (2007, 2007a). The vertical distribution of the suspended sediment concentration in the transport module depends on the effective settling velocity of the sediment, the bed shear velocity and the turbulence. The silt transport is simulated every time step together with the flow (online), which means that the impact of the calculated concentration is accounted for in the hydrodynamics. Major challenge was to accurately simulate the relatively high suspended silt concentrations observed near the estuarine turbidity maximum. 3 Results The paper will compare observed and predicted water levels, salinity distributions and suspended silt concentrations. Figure 1 shows an example of predicted depth-averaged suspended silt concentrations during spring high tide without waves. Under these conditions the depth-averaged concentrations decrease from about 2 kg/m3 in the Unterems (upstream of Emden) to almost zero seaward of Borkum. PIC Figure 1: Figure 2 Observed and predicted salinities in the upper part of the water column along the estuary The presence of waves will increase the concentrations on the shoals but have a limited effect on the concentrations in the channels. Figure 2 presents observed and predicted salinities along the estuary. The model results encouragingly agree with the observations. PIC 4 References De Jonge, V.N., 1992. Tidal flow and residual flow in the Ems estuary. Estuarine, Coastal and Shelf Science, 34: 1-22. Van Rijn, L.C., 2007. Unified View of Sediment Transport by Currents and Waves. I: Initiation of Motion, Bed Roughness, and Bed-Load Transport. Journal of Hydraulic Engineering, 133(6): 649-667. Van Rijn, L.C., 2007a. Unified View of Sediment Transport by Currents and Waves. II: Suspended Transport. Journal of Hydraulic Engineering, 133(6): 668-689.
Grasmeijer, B. T.
EM anomalies before the Kozani earthquake: A study of their behavior through laboratory experiments
Strong electromagnetic (EM) anomalies have been detected, from MHz to kHz, prior to the three destructive earthquakes occurred during 1995-1999 in Greece. The observed sequence of EM anomalies before the Kozani-Grevena earthquake (K-G) of Ms = 6.6 on May 13, 1995 showed some important characteristics: (i) an increasing electromagnetic emission rate; (ii) an emergence of lower kHz frequencies with large amplitudes at the tail of the MHz electromagnetic anomaly; (iii) an electromagnetic quiescence approximately a few hours before the earthquake and (iv) a total absence of EM anomalies during the aftershock period. All these features are compatible with those reported by other authors. This sequence of the field observed EM signals revealed, in terms of emission pattern, similarities to the laboratory acoustic (AE) emissions during different stages of failure preparation process in rocks.
Eftaxias, K.; Kapiris, P.; Dologlou, E.; Kopanas, J.; Bogris, N.; Antonopoulos, G.; Peratzakis, A.; Hadjicontis, V.
Remembering A.S. Kronrod \\Lambda E.M. Landis and I.M. Yaglom
Remembering A.S. Kronrod \\Lambda E.M. Landis and I.M. Yaglom Translation by Viola Brudno Edited --- even by his appearance --- he was tall and had a beautiful sonorous voice. While still a freshman, A
Laurie, Dirk
V.S. Ramachandran and E.M. Hubbard The Phenomenology of Synaesthesia
V.S. Ramachandran and E.M. Hubbard The Phenomenology of Synaesthesia Abstract: This article the phenomenology of synaesthesia in greater detail, raise several new questions that have emerged from recent
Ramachandran, Vilayanur S.
Hist¾rico demogrßfico e filogeografia em populań§es brasileiras de Ardea alba egretta.
??Foram estudadas populań§es de Ardea alba egretta (garńa-branca-grande) da famĒlia Ardeidae (Aves), amostradas em quatro regi§es brasileiras, com latitudes diferentes (Rio Grande do Sul, Pantanal,ģ (more)
ThaĒs Camilo CorrĻa
DegradańŃo de paracetamol empregando tecnologia oxidativa avanńada baseada em fotocatßlise heterogĻnea usando irradiańŃo artificial e solar.
??No presente trabalho avaliou-se a oxidańŃo e a mineralizańŃo do paracetamol, baseada em processos oxidativos avanńados, via fotocatßlise heterogĻnea. Estudou-se a ańŃo de dois fotocatalisadores:ģ (more)
Marcela Dias Franńa
Mars' Magnetic Atmosphere: Ionospheric Currents, Lightning (or not), E&M; Subsurface Sounding, and Future Missions
Mars' ionosphere has no obvious magnetic signs of large-scale, dust-produced lightning. However, there are numerous interesting ionospheric currents (some associated with crustal magnetic fields) which would allow for E&M; subsurface sounding.
Espley, J. R.; Connerney, J. E. P.
EM2006K-33 revised Identification of forces shaping the commensal Escherichia coli
1 EM2006K-33 revised Identification of forces shaping the commensal Escherichia coli genetic title: Commensal Escherichia coli ecological structure Key words: Escherichia coli, commensal, animal forces shaping the Escherichia coli intraspecies ecological structure, we have characterized in terms
Tide-driven fluid mud transport in the Ems estuary
The Ems estuary, located at the border between The Netherlands and Germany, experienced a significant change of the hydrodynamic regime during the past decades, as a result of extensive river engineering. With the net sediment transport now being flood-oriented, suspended sediment concentrations have increased dramatically, inducing siltation and formation of fluid mud layers, which, in turn, influence hydraulic flow properties, such as turbulence and the apparent bed roughness. Here, the process-based understanding of fluid mud is essential to model and predict mud accumulation, not only regarding the anthropogenic impact, but also in view of the expected changes of environmental boundary conditions, i.e., sea level rise. In the recent past, substantial progress has been made concerning the understanding of estuarine circulation and influence of tidal asymmetry on upstream sediment accumulation. While associated sediment transport formulations have been implemented in the framework of numerical modelling systems, in-situ data of fluid mud are scarce. This study presents results on tide-driven fluid mud dynamics, measured during four tidal cycles aside the navigation channel in the Ems estuary. Lutoclines, i.e., strong vertical density gradients, were detected by sediment echo sounder (SES). Acoustic Doppler current profiles (ADCP) of different acoustic frequencies were used to determine hydrodynamic parameters and the vertical distribution of suspended sediment concentrations in the upper part of the water column. These continuous profiling measurements were complemented by CTD, ADV, and OBS casts. SES and ADCP profiles show cycles of fluid mud entrainment during accelerating flow, and subsequent settling, and the reformation of a lutocline during decelerating flow and slack water. Significant differences are revealed between flood and ebb phase. Highest entrainment rates are measured at the beginning of the flood phase, associated with strong current shear and rapid vertical mixing, inducing the highest instantaneous suspended sediment flux measured during the tidal cycle. During decelerating flood currents a lutocline is again established at a certain distance above the consolidated river bed. During slack water after the flood phase the concentration gradient increases and the thickness of the fluid mud layer below is constant, also during a significant part of the ebb phase. As water depth decreases during ebb, entrainment occurs only at the upper part of the fluid mud layer. The suspended sediment flux is low compared to the flood phase. These observations are further elaborated using turbulence parameters obtained from ADV and ADCP, explaining the difference between ebb and flood concerning the vertical location of the maximum concentration gradient. This study is funded through DFG-Research Center / Excellence Cluster "The Ocean in the Earth System". The Senckenberg Institute and the Federal Waterways Engineering and Research Institute are acknowledged for technical support.
Becker, Marius; Maushake, Christian; Winter, Christian
Using EM to Obtain Asymptotic Variance-Covariance Matrices: The SEM Algorithm
The expectation maximization (EM) algorithm is a popular, and often remarkably simple, method for maximum likelihood estimation in incomplete-data problems. One criticism of EM in practice is that asymptotic variance¢covariance matrices for parameters (e.g., standard errors) are not automatic byproducts, as they are when using some other methods, such as Newton¢Raphson. In this article we define and illustrate a procedure
Xiao-Li Meng; Donald B. Rubin
Application of Fuzzy Logic to EMS-type Magnetically Levitated Railway Vehicle
A type of the magnetically levitated railway system with the electro-magnetic suspension system (EMS), which is named HSST system, will be put into revenue service as an urban transport in Nagoya, Japan at the beginning of April 2005. To extend its operational velocity higher than 200km\\/h for applications in other cities, the design of its EMS system is reexamined for
Shinichi Kusagawa; Jumpei Baba; Katsuhiko Shutoh; Eisuke Masada
; ┬Ę Resson^ancia Magn┬┤etica ┬Ł MRI. ┬Ł p. 12/6 #12;T├®cnicas para Gera├¦├Żo de Imagens em Medicina Nuclear ┬Ę Single Photon Emission Tomography ┬Ł SPECT, ┬Ę Positron Emission Tomograpy ┬Ł PET; ┬Ę Medicina Nuclear┬┤ogicas, microscopia, entre outros. ┬Ł p. 10/6 #12;T┬┤ecnicas para Gerac┬Ė~ao de Imagens em Medicina ┬Ł p. 11/6 #12
Pre-flight risk assessment in emergency medical service (EMS) helicopters
A preflight risk assessment system (SAFE) was developed at NASA-Ames Research Center for civil EMS operations to assist pilots in making a decision objectively to accept or decline a mission. The ability of the SAFE system to predict risk profiles was examined at an EMS operator. Results of this field study showed that the usefulness of SAFE was largely dependent on the type of mission flown.
Shively, Robert J.
Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports
Poor partitioning of macromolecules into the holes of holey carbon support grids frequently limits structural determination by single particle cryo-electron microscopy (cryo-EM). Here, we present a method to deposit, on gold-coated carbon grids, a self-assembled monolayer whose surface properties can be controlled by chemical modification. We demonstrate the utility of this approach to drive partitioning of ionotropic glutamate receptors into the holes, thereby enabling 3D structural analysis using cryo-EM methods. PMID:25403871
Meyerson, Joel R.; Rao, Prashant; Kumar, Janesh; Chittori, Sagar; Banerjee, Soojay; Pierson, Jason; Mayer, Mark L.; Subramaniam, Sriram
AN├üLISE DE SUPERF├ŹCIES BOMBARDEADAS POR FEIXES DE EL├?TRONS AUTOFOCALIZADOS EM UM SISTEMA DE PLAMA um consider├Īvel aumento de dureza e redu├¦├Żo de desgaste no material sem afetar suas propriedades feixes de el├®trons deslocando-se em um tubo contento um g├Īs de baixa densidade. A colis├Żo de el├®trons com
(continuao das responsabilidades) um estudo em que voc talvez se inscreva, possvel
(continua├¦├Żo das responsabilidades) um estudo em que voc├¬ talvez se inscreva, ├® poss├Łvel tamb├®m que tenha que assumir um conjunto geral de responsabilidades pertinentes a todos os participantes da com informa├¦├Żo. Caso tenha alguma d├║vida a respeito de seus direitos como volunt├Īrio em um estudo de
Oliver, Douglas L.
Helicopter-borne measurements of sea ice thickness, using a small and lightweight, digital EM system
Sea ice is an important climate variable and is also an obstacle for marine operations in polar regions. We have developed a small and lightweight, digitally operated frequency-domain electromagnetic-induction (EM) system, a so-called EM bird, dedicated for measurements of sea ice thickness. It is 3.5Ām long and weighs only 105Ākg, and can therefore easily be shipped to remote places and
Christian Haas; John Lobach; Stefan Hendricks; Lasse Rabenstein; Andreas Pfaffling
Colquio em homenagem ao centenrio da morte de Henri Poincar Rio de Janeiro
Col├│quio em homenagem ao centen├Īrio da morte de Henri Poincar├® Rio de Janeiro 27 a 30 de novembro Henri Poincar├® (Universit├® Nancy 2) Em 2012, ocorrer├Ī o primeiro centen├Īrio da morte do matem├Ītico morte de Poincar├®, al├®m de ser uma merecida homenagem a um cientista-fil├│sofo, cujas id├®ias ainda hoje
Solodov, Mikhail V.
The use of EM-CCDs on high resolution soft x-ray spectrometers
Charge-Coupled Devices (CCDs) have been traditionally used on high resolution soft X-ray spectrometers, but with their ability to increase the signal level in the detector before the readout noise of the system is added, Electron-Multiplying CCDs (EM-CCDs) have the potential to offer many advantages in soft X-ray detection. Through this signal multiplication an EM-CCD has advantages over conventioanl CCDs of
James H. Tutt; Andrew D. Holland; Neil J. Murray; Richard D. Harriss; David J. Hall; Matt Soman; Randall L. McEntaffer; James Endicott
Fast, simultaneous and robust VLF-EM data denoising and reconstruction via multivariate empirical mode decomposition
The measurement of Very Low Frequency Electromagnetic (VLF-EM) is important in many different applications, i.e, environmental, archeological, geotechnical studies, etc. In recent years, improving and enhancing VLF-EM data containing complex numbers (bivariate) was presented by several authors in order to produce reliable models, generally using univariate empirical mode decomposition (EMD). Applying univariate EMD separately on each data is problematic. This results in a different number of misaligned Intrinsic Mode Functions (IMFs) which can complicate the selection of some IMFs for denoising process. Thus, a filtering method based on the multivariate empirical mode decomposition (MEMD) approach to decompose simultaneously bivariate data is proposed. In this paper we address two issues by employing the recently introduced noise assisted MEMD (N-A MEMD) for improving bivariate VLF-EM data. Firstly, the N-A MEMD to decompose bivariate measurement of the VLF-EM data into IMFs and a residue is defined as VLF-EM signal or unwanted noise. Secondly, the proposed method is used to enhance VLF-EM data and to reject unwanted noise. Finally, the proposed method is applied to a synthetic data with two added sinusoids. To demonstrate the robustness of the N-A MEMD method, the method was tested on added-noise synthetic data sets and the results were compared to the Ensemble EMD (EEMD) and Bivariate EMD (BEMD). The N-A MEMD gave more robust and accurate results than the EEMD and BEMD methods and the method required less CPU time to obtain the IMFs compared to EEMD. The method was also tested on several field data sets. The results indicate that the filtered VLF-EM data based on the N-A MEMD make the data easier to interpret and to be analyzed further. In addition, the 2D resistivity profile estimated from the inversion of filtered VLF-EM data results was appropriate to the geological condition.
Sungkono; Bahri, Ayi S.; Warnana, Dwa D.; Monteiro Santos, Fernando A.; Santosa, Bagus J.
The Soils and Groundwater ¢ EM-20 S&T Roadmap Quality Assurance Project Plan
The Soils and Groundwater ¢ EM-20 Science and Technology Roadmap Project is a U.S. Department of Energy, Office of Environmental Management-funded initiative designed to develop new methods, strategies and technology for characterizing, modeling, remediating, and monitoring soils and groundwater contaminated with metals, radionuclides, and chlorinated organics. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by EM-20 Roadmap Project staff.
Fix, N. J.
Apresentase neste apndice a definio de categoria cartesiana livremente gerada, apresentada em [Sernadas et al 92e]. Tal como em [Admek et al 90], assumese que
'')├?Mor C P desde que (s:c┬«c')├?Mor C P e (s':c'┬«c'')├?Mor C P ; . ((s':c┬«c')├?(s'':c┬«c''):c┬«c'├?c'')├?Mor C P desde que (s':c┬«c')├?Mor C P e (s'':c┬«c'')├? Mor C P ; pela rela├¦├Żo de equival├¬ncia induzida pelas, apresentada em [Sernadas et al 92e]. Tal como em [Ad├Īmek et al 90], assume┬Łse que Cat denota a categoria de
Lisboa, Universidade T├®cnica de
High-speed computation of the EM algorithm for PET image reconstruction
The PET image reconstruction based on the EM algorithm has several attractive advantages over the conventional convolution backprojection algorithms. However, two major drawbacks have impeded the routine use of the EM algorithm, namely, the long computational time due to slow convergence and the large memory required for the storage of the image, projection data and the probability matrix. In this study, the authors attempts to solve these two problems by parallelizing the EM algorithm on a multiprocessor system. The authors have implemented an extended hypercube (EH) architecture for the high-speed computation of the EM algorithm using the commercially available fast floating point digital signal processor (DSP) chips as the processing elements (PEs). The authors discuss and compare the performance of the EM algorithm on a 386/387 machine, CD 4360 mainframe, and on the EH system. The results show that the computational speed performance of an EH using DSP chips as PEs executing the EM image reconstruction algorithm is about 130 times better than that of the CD 4360 mainframe. The EH topology is expandable with more number of PEs.
Rajan, K.; Patnaik, L.M.; Ramakrishna, J. (Indian Inst. of Science, Bangalore (India))
Anisotropic 3D inversion of towed streamer EM data from the Troll West oil province (Invited)
Obviating the need for ocean bottom receivers, the towed streamer EM system enables CSEM data to be acquired simultaneously with seismic over very large areas in frontier and mature basins for higher production rates and more cost effective than conventional marine CSEM. The towed streamer EM data are currently processed and delivered as a spectrum of frequency-domain responses. We apply a 3D anisotropic inversion methodology for towed streamer EM data that includes a moving sensitivity domain. Our implementation is based on the 3D contraction integral equation method for computing the EM responses and Frķchet derivatives, and uses the re-weighted regularized conjugate gradient method for minimizing the objective functional with focusing regularization. We present an actual case study for the 3D anisotropic inversion of towed streamer EM data from the Troll West oil province in the North Sea, and demonstrate our ability to image the Troll West Oil and Gas Provinces. We conclude that 3D anisotropic inversion of the data from the current generation of towed streamer EM system can adequately recover both the vertical and horizontal resistivities in anisotropic hydrocarbon-bearing formations.
Mattsson, J.; Midgley, J.; Zhdanov, M. S.; ENDO, M.
Visualizing Proteins and Macromolecular Complexes by Negative Stain EM: from Grid Preparation to Image Acquisition
Single particle electron microscopy (EM), of both negative stained or frozen hydrated biological samples, has become a versatile tool in structural biology 1. In recent years, this method has achieved great success in studying structures of proteins and macromolecular complexes 2, 3. Compared with electron cryomicroscopy (cryoEM), in which frozen hydrated protein samples are embedded in a thin layer of vitreous ice 4, negative staining is a simpler sample preparation method in which protein samples are embedded in a thin layer of dried heavy metal salt to increase specimen contrast 5. The enhanced contrast of negative stain EM allows examination of relatively small biological samples. In addition to determining three-dimensional (3D) structure of purified proteins or protein complexes 6, this method can be used for much broader purposes. For example, negative stain EM can be easily used to visualize purified protein samples, obtaining information such as homogeneity/heterogeneity of the sample, formation of protein complexes or large assemblies, or simply to evaluate the quality of a protein preparation. In this video article, we present a complete protocol for using an EM to observe negatively stained protein sample, from preparing carbon coated grids for negative stain EM to acquiring images of negatively stained sample in an electron microscope operated at 120kV accelerating voltage. These protocols have been used in our laboratory routinely and can be easily followed by novice users. PMID:22215030
Booth, David S.; Avila-Sakar, Agustin; Cheng, Yifan
Reservoir characterization and process monitoring with EM methods. 1994 Annual report
During the past five years at Lawrence Livermore National Laboratory (LLNL) the authors have applied the EM induction method to the problem of petroleum reservoir characterization and enhanced oil recovery (EOR) monitoring. The goal is to develop practical tools for determining the electrical resistivity distribution between boreholes at a useful scale for reservoir characterization. During FY94 the authors conducted their largest field test to date. They applied crosshole and surface-to-borehole EM techniques to reservoir characterization at the Los Hills No. 3 oil field making three sets of measurements during the initial phase of the steam drive.From these data they were able to determine the resistivity and configuration of the oil sands, between the observation wells, and provide an image of the subsurface resistivity changes due to the steam drive. They also conducted a waterflood experiment at the Richmond Field Station facility using the borehole-to-surface EM technique. For this test they injected a small quantity of saltwater, and applied the Em technique to monitor the progress of the injected plume. Data collection for this experiment is complete but the results are yet to be interpreted. Finally, a project to understand EM propagation through steel casing was initiated in 1994. The goals of the experiment are to determine the limits and applications for crosswell EM surveys through steel well casing.
Wilt, M.
If EM waves don't interfere, what causes interferograms?
Photonics engineers involved in designing and operating Fourier transform spectrometers (FTS) often rely on Maxwell's wave equations and time-frequency (distance-wavenumber) Fourier theory as models to understand and predict the conversion of optical energy to electrical signals in their instruments. Dr. Chandrasekhar Roychoudhuri and his colleagues, at last year's conference, presented three significant concepts that might completely change the way we comprehend the interaction of light and matter and the way interference information is generated. The first concept is his non-interaction of waves (NIW) formulation, which puts in place an optical wave description that more accurately describe the properties of the finite time and spatial signals of an optical system. The second is a new description for the cosmic EM environment that recognizes that space is really filled with the ether of classical electromagnetics. The third concept is a new metaphysics or metaphotonics that compares the photon as a particle in a void against the photon as a wave in a medium to see which best explain the twelve different aspects of light. Dr. Henry Lindner presents a compelling case that photons are waves in a medium and particles (electrons, protons, atoms) are wave-structures embedded in the new ether. Discussion of the three new principles is intended to increase the curiosity of photonics engineers to investigate these changes in the nature of light and matter.
Wellard, Stanley J.
The tidal asymmetries and residual flows in Ems Estuary
A 3D unstructured-grid numerical model of the Ems Estuary is presented. The simulated hydrodynamics are compared against tidal gauge data and observations from research cruises. A comparison with an idealized test reveals the capability of the model to reproduce the secondary circulation patterns known from theoretical results. The simulations prove to be accurate and realistic, confirming and extending findings from earlier observations and modeling studies. The basic characteristics of dominant physical processes in the estuary such as tidal amplification, tidal damping, overtide generation, baroclinicity and internal mixing asymmetry are quantified. The model demonstrates an overall dominance of the flood currents in most of the studied area. However, the hypsometric control in the vicinity of Dollart Bay reverses this asymmetry, with the ebb currents stronger than the flood ones. Small-scale bathymetric characteristics and baroclinicity result in a very complex interplay between dominant physical mechanisms in different parts of the tidal channels and over the tidal flats. Residual flow reveals a clear overturning circulation in some parts of the estuary which is related to a mixing asymmetry between flood and ebb currents. We demonstrate that while areas close to the tidal river exhibit overall similarity with density controlled estuarine conditions, in large areas of the outer estuary barotropic forcing and complex bathymetry together with the density distribution affect substantially the horizontal circulation.
Pein, Johannes Ulrich; Stanev, Emil Vassilev; Zhang, Yinglong Joseph
EM modeling for GPIR using 3D FDTD modeling codes
An analysis of the one-, two-, and three-dimensional electrical characteristics of structural cement and concrete is presented. This work connects experimental efforts in characterizing cement and concrete in the frequency and time domains with the Finite Difference Time Domain (FDTD) modeling efforts of these substances. These efforts include Electromagnetic (EM) modeling of simple lossless homogeneous materials with aggregate and targets and the modeling dispersive and lossy materials with aggregate and complex target geometries for Ground Penetrating Imaging Radar (GPIR). Two- and three-dimensional FDTD codes (developed at LLNL) where used for the modeling efforts. Purpose of the experimental and modeling efforts is to gain knowledge about the electrical properties of concrete typically used in the construction industry for bridges and other load bearing structures. The goal is to optimize the performance of a high-sample-rate impulse radar and data acquisition system and to design an antenna system to match the characteristics of this material. Results show agreement to within 2 dB of the amplitudes of the experimental and modeled data while the frequency peaks correlate to within 10% the differences being due to the unknown exact nature of the aggregate placement.
Nelson, S.D.
14-3-3 proteins are part of an abscisic acid-VIVIPAROUS1 (VP1) response complex in the Em promoter and interact with VP1 and EmBP1.
Protein-DNA complexes were formed when nuclear extracts from embryogenic rice suspension cultures or maize embryos were incubated with an abscisic acid-VIVIPAROUS1 (VP1) response element (Em1a) from the Em promoter. Monoclonal antibodies generated to GF14, a 14-3-3 protein from plants, resulted in gel retardation of the Em1a-protein complexes. Antibodies generated to the C and N termini of GF14 detected protein isoforms in rice nuclear and cytoplasmic extracts, but no differences in distribution of the GF14 isoforms were recognized between the nucleus and cytoplasm or when abscisic acid-treated and untreated tissues were compared. When recombinant GF14 fusion proteins from rice were added to nuclear extracts, novel complexes were formed that required the dimerization domain of GF14. Chemical cross-linking showed that GF-14 interacted with the basic leucine zipper factor EmBP1, which binds specifically to Em1a, and with VP1, which transactivates Em through Em1a. GF14 proteins from rice were shown to interact with VP1 in yeast through the dimerization domain of GF14. Our results indicated that GF14 interacts with both site-specific DNA binding proteins (i.e., EmBP1) and tissue-specific regulatory factors (i.e., VP1) and may provide a structural link between VP1 and the Em1a transcriptional complex. PMID:9596641
Schultz, T F; Medina, J; Hill, A; Quatrano, R S
PrevalĻncia de adońŃo intra e extrafamiliar em amostras clĒnica e nŃo-clĒnica de crianńas e adolescentes Prevalence of intrafamilial and extrafamilial adoption in a clinical and non-clinical setting samples of children and adolescents
IntroduńŃo\\/Objetivos: Estudos realizados em diferentes paĒses demonstram que a proporńŃo de crianńas e ado- lescentes adotivos atendidos em clĒnicas psiquißtricas ķ maior em relańŃo Ó verificada nas demais clĒnicas e na populańŃo em geral. O objetivo deste estudo ķ verificar a prevalĻncia de adońŃo em amostra clĒnica e nŃo-clĒnica, identificando possĒveis associań§es entre tipos de adońŃo (extrafamiliar e intrafamiliar) e
Lee Fu I; Eneida B Matarazzo
Programa de Ps-Graduao em Literatura, Cultura e Contemporaneidade Rua Marqus de So Vicente, 225 -Gvea -22453-900
de P├│s-Gradua├¦├Żo em Literatura, Cultura e Contemporaneidade Rua Marqu├¬s de S├Żo Vicente, 225 - G├Īvea@puc-rio.br - www.letras.puc-rio.br PROGRAMA DE P├?S-GRADUA├?├?O EM LITERATURA, CULTURA E CONTEMPORANEIDADE EDITAL;__________________________________________________________________________________________________ Programa de P├│s-Gradua├¦├Żo em Literatura, Cultura e Contemporaneidade Rua Marqu├¬s de S├Żo Vicente, 225
EM-54 Technology Development In Situ Remediation Integrated Program. Annual report
The Department of Energy (DOE) established the Office of Technology Development (EM-50) as an element of Environmental Restoration and Waste Management (EM) in November 1989. EM manages remediation of all DOE sites as well as wastes from current operations. The goal of the EM program is to minimize risks to human health, safety and the environment, and to bring all DOE sites into compliance with Federal, state, and local regulations by 2019. EM-50 is charged with developing new technologies that are safer, more effective and less expensive than current methods. The In Situ Remediation Integrated Program (the subject of this report) is part of EM-541, the Environmental Restoration Research and Development Division of EM-54. The In Situ Remediation Integrated Program (ISR IP) was instituted out of recognition that in situ remediation could fulfill three important criteria: Significant cost reduction of cleanup by eliminating or minimizing excavation, transportation, and disposal of wastes; reduced health impacts on workers and the public by minimizing exposure to wastes during excavation and processing; and remediation of inaccessible sites, including: deep subsurfaces; in, under, and around buildings. Buried waste, contaminated soils and groundwater, and containerized wastes are all candidates for in situ remediation. Contaminants include radioactive wastes, volatile and non-volatile organics, heavy metals, nitrates, and explosive materials. The ISR IP tends to facilitate development of in situ remediation technologies for hazardous, radioactive, and mixed wastes in soils, groundwater, and storage tanks. Near-term focus is on containment of the wastes, with treatment receiving greater effort in future years.
Noninvasive monitoring of CO2 sequestration sites using airborne EM technology
Usage of conventional airborne EM methods for studies related to CO2 sequestration reservoirs have been restricted up to date due to depth and system noise limitations. Recently a family of new EM systems was developed and launched in Canada, allowing superior depth of investigation to that of the conventional EM systems. Depending on the resistivity of the area such systems are capable of recording response from targets emplaced at the depths of up to 2 kilometers below surface. These systems are powered by natural (telluric and storm lightning) EM fields and are particularly sensitive to contrast in electrical properties of the subsurface, rather than absolute values of the conductivities, which make these systems suitable for usage in both resistive and conductive environments, including the subsurface identification and mapping of gas, hydrocarbons, liquid CO2 and supercritical CO2. Based on the well log data collected at one of the proposed sequestration sites, forward modeling has been carried out in order to study which changes in electrical properties of reservoir rocks before and after the introduction of CO2 to the sequestration reservoir are sufficient to provide enough contrast so they become detectable by EM systems. The results of the modeling showed that under favourable conditions it is possible to differentiate between brine-filled reservoirs versus CO2-filled reservoir at a depth of more than 1 kilometer with the main controlling parameters being reservoir effective porosity, thickness, Total Dissolved Solids (TDS) content of the pore-filling fluid and CO2 saturation after the injection. EM surveying can play a crucial role in studies of moderately deep-seated reservoirs, specifically can assist in monitoring CO2 injection and migration and can provide some additional data regarding the CO2 saturation level. The benefits of application of these new EM systems compared with 3D reflection seismic, VSP, gravity, and other geophysical methods will also be discussed.
Kaminski, V.; Harbert, W. P.; Legault, J. M.
Intra- and extracellular regulation of activity and processing of legumain by cystatin E/M.
Legumain, an asparaginyl endopeptidase, is up-regulated in tumour and tumour-associated cells, and is linked to the processing of cathepsin B, L, and proMMP-2. Although legumain is mainly localized to the endosomal/lysosomal compartments, legumain has been reported to be localized extracellularly in the tumour microenvironment and associated with extracellular matrix and cell surfaces. The most potent endogenous inhibitor of legumain is cystatin E/M, which is a secreted protein synthesised with an export signal. Therefore, we investigated the cellular interplay between legumain and cystatin E/M. As a cell model, HEK293 cells were transfected with legumain cDNA, cystatin E/M cDNA, or both, and over-expressing monoclonal cell lines were selected (termed M38L, M4C, and M3CL, respectively). Secretion of prolegumain from M38L cells was inhibited by treatment with brefeldin A, whereas bafilomycin A1 enhanced the secretion. Cellular processing of prolegumain to the 46 and 36 kDa enzymatically active forms was reduced by treatment with either substance alone. M38L cells showed increased, but M4C cells decreased, cathepsin L processing suggesting a crucial involvement of legumain activity. Furthermore, we observed internalization of cystatin E/M and subsequently decreased intracellular legumain activity. Also, prolegumain was shown to internalize followed by increased intracellular legumain processing and activation. In addition, in M4C cells incomplete processing of the internalized prolegumain was observed, as well as nuclear localized cystatin E/M. Furthermore, auto-activation of secreted prolegumain was inhibited by cystatin E/M, which for the first time shows a regulatory role of cystatin E/M in controlling both intra- and extracellular legumain activity. PMID:22902879
Smith, Robert; Johansen, Harald T; Nilsen, Hilde; Haugen, Mads H; Pettersen, Solveig J; Mµlandsmo, Gunhild M; Abrahamson, Magnus; Solberg, Rigmor
Does contamination buildup limit throughput for automated cryoEM?
The development of automated systems for data acquisition in cryo electron microscopy has enabled the possibility of acquiring very large number of images from a single specimen grid. We have demonstrated that over images of 250,000 single particles can be acquired in a 24 h period. This has raised questions as to whether contamination buildup on the specimen limits the quality of the data that can be acquired during these long duration experiments and also whether the data acquisition session could be extended to allow acquisition of more than 1,000,000 particles. We report here a systematic characterization of contamination of specimens maintained for long periods of time at liquid nitrogen temperatures using standard side entry cryo stages. As part of this characterization we developed a more reliable method for accurately estimating specimen ice thickness. Using the method, we were able to calibrate image contrast against ice thickness under a variety of magnifications, objective aperture positions, and defoci, and demonstrated the strong dependence of the calibration curve on these parameters. The results show the anti-contamination aperture is, as expected, critical to the prevention of contamination and that loading film into the microscope dramatically increases the contamination rate, particularly in the first 3 h after the insertion of the film box. In the absence of film, we were able to reproducibly demonstrate that the contamination rate can be limited to a rate of approximately 1 angstrom/h providing reassurance that contamination will not be a major limiting factor for long term cryoEM experiments if a CCD camera is used for the imaging. PMID:16632377
Cheng, Anchi; Fellmann, Denis; Pulokas, James; Potter, Clinton S; Carragher, Bridget
Elimination of error factors, affecting EM and seismic inversions
EM or seismic data inversions are affected by many factors, which may conceal the responses from target objects. We address here the contributions from the following effects: 1) Pre-survey spectral sensitivity factor. Preliminary information about a target layer can be used for a pre-survey estimation of the required frequency domain and signal level. A universal approach allows making such estimations in real time, helping the survey crew to optimize an acquisition process. 2) Preliminary velocities' identification and their dispersions for all the seismic waves, arising in a stratified media became a fast working tool, based on the exact analytical solution. 3) Vertical gradients effect. For most layers the log data scatter, requiring an averaging pattern. A linear gradient within each representative layer is a reasonable compromise between required inversion accuracy and forward modeling complexity. 4) An effect from the seismic source's radial component becomes comparable with vertical part for explosive sources. If this effect is not taken into account, a serious modeling error takes place. This problem has an algorithmic solution. 5) Seismic modeling is often based on different representations for a source formulated either for a force or to a potential. The wave amplitudes depend on the formulation, making an inversion result sensitive to it. 6) Asymmetrical seismic waves (modified Rayleigh) in symmetrical geometry around liquid fracture come from S-wave and merge with the modified Krauklis wave at high frequencies. A detail analysis of this feature allows a spectral range optimization for the proper wave's extraction. 7) An ultrasonic experiment was conducted to show different waves appearance for a super-thin water-saturated fracture between two Plexiglas plates, being confirmed by comparison with theoretical computations. 8) A 'sandwich effect' was detected by comparison with averaged layer's effect. This opens an opportunity of the shale gas direct identification from the surface measurements.
Magomedov, M.; Zuev, M. A.; Korneev, V. A.; Goloshubin, G.; Zuev, J.; Brovman, Y.
Immunohistochemical distribution of the secretogranin II-derived peptide EM66 in the rat hypothalamus: a comparative study with jerboa.
EM66 is a 66-amino acid peptide derived from secretogranin II, a member of granin acidic secretory protein family, by proteolytic processing. EM66 has been previously characterized in the jerboa (Jaculus orientalis) hypothalamus and its potential implication in the neuroendocrine regulation of feeding behaviour has been demonstrated. In the present study, an immunohistochemical analysis of the localization of EM66 within hypothalamic structures of rat was performed and compared to the distribution of EM66 in the jerboa hypothalamus. In the rat hypothalamus, as in the jerboa, EM66 immunostaining was detected in the parvocellular paraventricular, preoptic and arcuate nuclei, as well as the lateral hypothalamus which displayed an important density of EM66-producing neurones. However, unlike jerboa, the suprachiasmatic and supraoptic nuclei of the rat hypothalamus were devoid of cellular EM66-immunolabeling. Thus, the novel peptide EM66 may exert common neuroendocrine activities in rat and jerboa, e.g. control of food intake, and species-specific roles in jerboa such as the regulation of biological rhythms and hydromineral homeostasis. These results suggest the existence of differences between jerboas and rats in neuroendocrine regulatory mechanisms involving EM66. PMID:17240057
Boutahricht, Mohammed; Guillemot, Johann; Montero-Hadjadje, Maitķ; Barakat, Youssef; El Ouezzani, Seloua; Alaoui, Abdelilah; Yon, Laurent; Vaudry, Hubert; Anouar, Youssef; Magoul, Rabia
PadronizańŃo de testes neurocomportamentais para investigańŃo da importŌncia funcional do wulst visual em corujas buraqueiras (Athene cunicularia).
??As aves tĻm sido utilizadas em numerosos estudos envolvendo habilidades visuo-cognitivas, constituindo um excelente modelo para a neurolobiologia comparativa. Vßrios estudos jß demonstraram que naģ (more)
Leticia Mercedes Gomes Correia Martins
??Este trabalho objetivou verificar os achados laboratoriais e histol¾gicos da infecńŃo experimental por Trypanosoma (Trypanozoon) evansi (Steel, 1885) Balbiani, 1888, em ratos (Rattus norvegicus) daģ (more)
Rovaina Laureano Doyle
Pre-flight risk assessment in Emergency Medical Service (EMS) helicopters
The Emergency Medical Service (EMS) industry has been the subject of several television and newspaper articles (Harvey and Jensen, 1987) which emphasized the negative aspects, (e.g., fatalities and high accident rates), rather than the life saving services performed. Until recently, the accident rate of the EMS industry has been five times as high as that of other civil helicopters. This high accident rate has been coupled with the dramatic rise in the number of programs. The industry has built from a single service at its inception in 1972, to over 180 in 1987 (Spray, 1987), to the point that 93 percent of the contiguous U.S. is now covered by some type of EMS service. These factors prompted the National Transportation Safety Board (NTSB) to study the accidents that occurred between May 11, 1978 and December 3, 1986 (NTSB, 1988). The NTSB report concluded that 'Sound pilot judgment is central to safe flight operations.' They further stated that '... factors unique to EMS helicopter operations--such as the influence of the mission itself, program competition, and EMS program management perspectives--can drastically influence pilot judgment during the EMS mission.' One of the most difficult decisions that a pilot must make is whether to accept or decline a mission. A pre-flight risk assessment system (SAFE) was developed at NASA-Ames Research Center for civil EMS operations to aid pilots in making this decision objectively. The ability of the SAFE system to predict mission risk profiles was tested at an EMS facility. The results of this field study demonstrated that the usefulness of SAFE was highly dependent on the type of mission flown. SAFE is now being modified so that it can 'learn' with each mission flown. For example, after flying a mission to a particular site, an EMS pilot would input information about this mission into the system, such as new buildings, wires, or approach procedures. Then, the next time a pilot flew a similar mission or one to the same area, this additional information would be taken into account in computing a risk assessment.
Shively, R. J.
Scalable and Interactive Segmentation and Visualization of Neural Processes in EM Datasets
Recent advances in scanning technology provide high resolution EM (Electron Microscopy) datasets that allow neuroscientists to reconstruct complex neural connections in a nervous system. However, due to the enormous size and complexity of the resulting data, segmentation and visualization of neural processes in EM data is usually a difficult and very time-consuming task. In this paper, we present NeuroTrace, a novel EM volume segmentation and visualization system that consists of two parts: a semi-automatic multiphase level set segmentation with 3D tracking for reconstruction of neural processes, and a specialized volume rendering approach for visualization of EM volumes. It employs view-dependent on-demand filtering and evaluation of a local histogram edge metric, as well as on-the-fly interpolation and ray-casting of implicit surfaces for segmented neural structures. Both methods are implemented on the GPU for interactive performance. NeuroTrace is designed to be scalable to large datasets and data-parallel hardware architectures. A comparison of NeuroTrace with a commonly used manual EM segmentation tool shows that our interactive workflow is faster and easier to use for the reconstruction of complex neural processes. PMID:19834227
Jeong, Won-Ki; Beyer, Johanna; Hadwiger, Markus; Vazquez, Amelio; Pfister, Hanspeter; Whitaker, Ross T.
Comunicantes domiciliares jovens de pacientes com TB pulmonar na regiŃo da grande Vit¾ria (ES): um estudo de coorte* Juvenile household contacts aged 15 or younger of patients with pulmonary TB in the greater metropolitan area of Vit¾ria, Brazil: a cohort study
Resumo Objetivo: Comparar aspectos clĒnicos, radiol¾gicos e laboratoriais de contatos domiciliares, menores de 15 anos, de pacientes com cultura positiva para Mycobacterium tuberculosis. Mķtodos: Realizou-se um estudo de coorte comparando crianńas e adolescentes (? 15 anos) que eram contatos domiciliares de casos de TB com baciloscopia e cultura positiva (grupo exposto, n = 100) ou com baciloscopia negativa e cultura
Ethel Leonor; Noia Maciel; Luiza Werner; Heringer Vieira; LucĒlia Pereira Dutra Molina; Rosana Alves; Reynaldo Dietze
Los Ēndices de mortalidad por cßncer de pulm¾n siguen bajando y contribuyen a reducci¾n de Ēndices generales de muertes por cßncer; Informe Anual a la Naci¾n tiene una secci¾n especial de los efectos de otras enfermedades en la supervivencia de pacientes
El Informe Anual a la Naci¾n sobre el Estado del Cßncer (1975 a 2010), mostr¾ un descenso mßs acelerado que en a±os anteriores de los Ēndices de mortalidad por cßncer de pulm¾n. Tambiķn contiene una secci¾n especial que destaca los efectos significativos que tienen otras enfermedades en la supervivencia de pacientes con cßncer.
C¾digo para imageamento indireto de estrelas em sistemas binarios: simulańŃo de variań§es elipsoidais e do perfil das linhas
As estrelas secundßrias em varißveis cataclĒ smicas (VCs) e binßrias-x de baixa massa (BXBMs) sŃo cruciais para o entendimento da origem, evoluńŃo e comportamento destas binßrias interagentes. Elas sŃo estrelas magneticamente ativas submetidas a condiń§es ambientais extremas [e.g., estŃo muito pr¾ximas de uma fonte quente e irradiante; tĻm rotańŃo extremamente rßpida e forma distorcida; estŃo perdendo massa a taxas de 10-8-10-10 Mż/ano] que contribuem para que suas propriedades sejam distintas das de estrelas de mesma massa na seq³Ļncia principal. Por outro lado, o padrŃo de irradiańŃo na face da secundßria fornece informańŃo sobre a geometria das estruturas de acrķscimo em torno da estrela primßria. Assim, a obtenńŃo de imagens da superfĒcie destas estrelas ķ de grande interesse astrofĒsico. A Tomografia Roche usa as variań§es no perfil das linhas de emissŃo/absorńŃo da estrela secundßria em funńŃo da fase orbital para mapear a distribuińŃo de brilho em sua superfĒcie. Neste trabalho apresentamos os resultados iniciais do desenvolvimento de um programa para o mapeamento da distribuińŃo de brilho na superfĒ cie das estrelas secundßrias em VCs e BXBMs com tķcnicas de astro-tomografia. Presentemente temos em operańŃo um c¾digo que simula as variań§es no perfil das linhas em conseq³Ļncia de efeito Doppler resultante da combinańŃo de rotańŃo e translańŃo de uma estrela em forma de lobo de Roche em torno do centro de massa da binßria, em funńŃo da distribuińŃo de brilho na superfĒcie desta estrela. O c¾digo igualmente produz a curva de luz resultante das variań§es de aspecto da estrela em funńŃo da fase orbital (variań§es elipsoidais).
Souza, T. R.; Baptista, R.
An Ems-Sensitivity Factor in Maize Conditioning Albino Leaf Stripes
A description is given for a recessive EMS-sensitivity factor conditioning albino leaf stripes. In the homozygous condition, there is low frequency of spontaneous leaf stripes. EMS, depending on the concentration, increases markedly the frequency of the stripes in 100% of the treated plants. The effects of EMS, given to the seeds, starts to appear from the 6th to 7th leaf and persists in all the leaves throughout the life cycle of the M1 plants. Only about 20¢25% of the M2 plants showed some variegation. These variegated M2 plants were not distributed at random among the different ear-to-row M2 rows. PMID:17248674
Efron, Y.
Evaluation model calculations with the water reactor analysis package (WRAP-EM)
The Water Reactor Analysis Package-Evaluation Model (WRAP-EM) is a modular system of computer codes designed to provide the safety analyst with the capability of performing complete loss-of-coolant calculations for both pressurized- and boiling-water reactor systems. The system provides a licensing-type calculation capability and thus contains most of the Nuclear Regulatory Commission-Approved EM options, as described in the Code of Federal Regulations, Title 10, Part 50, Appendix K. All phases of an accident (blowdown, refill, and reflood) are modeled. The WRAP consists of modified versions of five preexisting codes (RELAP4/MOD5, GAPCON, FRAP, MOXY, and NORCOOL), the necessary interfaces to permit automatic transition from one code to the next during the transient calculations, plus a host of user-convenience features to aid the analyst faced with a multitude of EM calculations. The WRAP has been verified against both calculated and experimental results.
Gregory, M.V.; Beranek, F.
Fabs enable single particle cryoEM studies of small proteins
Summary In spite of its recent achievements, the technique of single particle electron cryomicroscopy (cryoEM) has not been widely used to study proteins smaller than 100kDa, although it is a highly desirable application of this technique. One fundamental limitation is that images of small proteins embedded in vitreous ice do not contain adequate features for accurate image alignment. We describe a general strategy to overcome this limitation by selecting a fragment antigen binding (Fab) to form a stable and rigid complex with a target protein, thus providing a defined feature for accurate image alignment. Using this approach, we determined a three-dimensional structure of a ~65 kDa protein by single particle cryoEM. Because Fabs can be readily generated against a wide range of proteins by phage display, this approach is generally applicable to study many small proteins by single particle cryoEM. PMID:22483106
Wu, Shenping; Avila-Sakar, Agustin; Kim, JungMin; Booth, David S.; Greenberg, Charles H.; Rossi, Andrea; Liao, Maofu; Li, Xueming; Alian, Akram; Griner, Sarah L.; Juge, Narinobu; Yu, Yadong; Mergel, Claudia M.; Chaparro-Riggers, Javier; Strop, Pavel; Tampe, Robert; Edwards, Robert H.; Stroud, Robert M.; Craik, Charles S.; Cheng, Yifan
OsLEA1a, a new Em-like protein of cereal plants.
Proteins abundant in seeds during the late stages of development, late embryogenesis abundant (LEA) proteins, are associated with desiccation tolerance. More than 100 of the group I LEA genes, also termed Em genes, have been identified from plants, bacteria and animals. The wide distribution indicates the functional importance of these genes. In the present study, we characterized a novel Em-like gene, OsLEA1a of rice (Oryza sativa). The encoded OsLEA1a protein has an N-terminal sequence similar to that of other plant Em proteins but lacks a 20-mer motif that is the most significant feature of typical Em proteins. The location of the sole intron indicates that the second exon of OsLEA1a is the mutated product of a typical Em gene. Transcriptome analysis revealed OsLEA1a mainly expressed in embryos, with no or only a few transcripts in osmotic stress-treated vegetative tissues. Structural analysis revealed that the OsLEA1a protein adopts high amounts of disordered conformations in solution and undergoes desiccation-induced conformational changes. Macromolecular interaction studies revealed that OsLEA1a protein interacts with non-reducing sugars and phospholipids but not poly-l-lysine. Thus, although the OsLEA1a protein lost its 20-mer motif, it is still involved in the formation of bioglasses with non-reducing sugars or plasma membrane. However, the protein does not function as a chaperone as do other groups of hydrophilic LEA proteins. The orthologs of the OsLEA1a gene had been identified from various grasses but not in dicot plants. Genetic analysis indicated that rice OsLEA1a locates at a 193 kb segment in chromosome 1 and is conserved in several published cereal genomes. Thus, the ancestor of Em-like genes might have evolved after the divergence of monocot plants. PMID:21097897
Shih, Ming-Der; Huang, Lin-Tzu; Wei, Fu-Jin; Wu, Ming-Tsung; Hoekstra, Folkert A; Hsing, Yue-Ie C
A distribuińŃo de velocidades na linha de visada em galßxias barradas vistas de face
Com o objetivo de realizar um estudo cinemßtico da componente vertical de barras em galßxias, obtivemos espectros de fenda longa de alta razŃo S/N ao longo dos eixos maior e menor de 14 galßxias barradas vistas de face, nos telesc¾pios de 1.52m do ESO em La Silla, Chile, e de 2.3m do Steward Observatory em Kitt Peak, Arizona. Estes dados nos permitiram determinar a distribuińŃo de velocidades das estrelas ao longo do eixo vertical das barras e discos destes sistemas, tanto no centro como em pontos que distam cerca de 5 e 20 segundos de arco do n·cleo, correspondendo a distŌncias de cerca de 0.7 e 2.8 kpc, respectivamente. Desta forma, a variańŃo radial da distribuińŃo de velocidades tambķm p¶de ser avaliada. Este tipo de anßlise tem raros exemplos na literatura por ser caro em termos de tempo de telesc¾pio. Entretanto, ķ de fßcil justificativa, considerando que traz novas informań§es que podem ser utilizadas para aperfeińoar modelos te¾ricos acerca da formańŃo e evoluńŃo de galßxias. Um algoritmo por n¾s desenvolvido foi utilizado para obter as distribuiń§es de velocidades como Gaussianas generalizadas (polin¶mios de Gauss-Hermite), o que traz um ingrediente a mais neste tipo de estudo que, tradicionalmente, se utiliza de Gaussianas puras, uma hip¾tese nem sempre razoßvel. Apresentaremos os resultados deste trabalho, que incluem um diagn¾stico para a identificańŃo de barras recķm formadas, e testes para o modelo isotķrmico de discos. Mostraremos que: (i) a escolha das estrelas padrŃo em velocidade, e dos parŌmetros da Gaussiana, deve ser muito bem justificada jß que tem influĻncia significativa nos resultados; (ii) muitas galßxias apresentam uma depressŃo na dispersŃo de velocidades na regiŃo central, que pode estar associada a um disco interno; e (iii) a dispersŃo de velocidades ķ constante ao longo da barra, nos eixos maior e menor, mas cai substancialmente quando se passa da barra para o disco.
Gadotti, D. A.; de Souza, R. E.
The longitudinal study of turnover and the cost of turnover in EMS
Purpose Few studies have examined employee turnover and associated costs in emergency medical services (EMS). The purpose of this study was to quantify the mean annual rate of turnover, total median cost of turnover, and median cost per termination in a diverse sample of EMS agencies. Methods A convenience sample of 40 EMS agencies was followed over a 6 month period. Internet, telephone, and on-site data collection methods were used to document terminations, new hires, open positions, and costs associated with turnover. The cost associated with turnover was calculated based on a modified version of the Nursing Turnover Cost Calculation Methodology (NTCCM). The NTCCM identified direct and indirect costs through a series of questions that agency administrators answered monthly during the study period. A previously tested measure of turnover to calculate the mean annual rate of turnover was used. All calculations were weighted by the size of the EMS agency roster. The mean annual rate of turnover, total median cost of turnover, and median cost per termination were determined for 3 categories of agency staff mix: all paid staff, mix of paid and volunteer (mixed), and all-volunteer. Results The overall weighted mean annual rate of turnover was 10.7%. This rate varied slightly across agency staffing mix: (all-paid=10.2%, mixed=12.3%, all-volunteer=12.4%). Among agencies that experienced turnover (n=25), the weighted median cost of turnover was $71,613.75, which varied across agency staffing mix: (all-paid=$86,452.05, mixed=$9,766.65, and all-volunteer=$0). The weighted median cost per termination was $6,871.51 and varied across agency staffing mix: (all-paid=$7,161.38, mixed=$1,409.64, and all-volunteer=$0). Conclusions Annual rates of turnover and costs associated with turnover vary widely across types of EMS agencies. The studyÆs mean annual rate of turnover was lower than expected based on information appearing in the news media and EMS trade magazines. Findings provide estimates of two key workforce measures ¢ turnover rates and costs ¢ where previously none have existed. Local EMS directors and policymakers at all levels of government may find the results and study methodology useful towards designing and evaluating programs targeting the EMS workforce. PMID:20199235
Patterson, P. Daniel; Jones, Cheryl B.; Hubble, Michael W.; Carr, Matthew; Weaver, Matthew D.; Engberg, John; Castle, Nicholas
Quality assurance guidance for laboratory assessment plates in support of EM environmental sampling and analysis activities
This document is one of several guidance documents developed to support the EM (DOE Environmental Restoration and Waste Management) Analytical Services program. Its purpose is to introduce assessment plates that can be used to conduct performance assessments of an organization`s or project`s ability to meet quality goals for analytical laboratory activities. These assessment plates are provided as non-prescriptive guidance to EM-support organizations responsible for collection of environmental data for remediation and waste management programs at DOE facilities. The assessments evaluate objectively all components of the analytical laboratory process to determine their proper selection and use.
ModEM: A modular system for inversion of electromagnetic geophysical data
We describe implementation of a modular system of computer codes for inversion of electromagnetic geophysical data, referred to as ModEM. The system is constructed with a fine level of modular granularity, with basic components of the inversion - forward modeling, sensitivity computations, inversion search algorithms, model parametrization and regularization, data functionals - interchangeable, reusable and readily extensible. Modular sensitivity computations and generic interfaces to parallelized inversion algorithms provide a ready framework for rapid implementation of new applications or inversion algorithms. We illustrate the code's versatility and capabilities for code reuse through implementation of 3D magnetotelluric (MT) and controlled-source EM (CSEM) inversions, using essentially the same components.
Kelbert, Anna; Meqbel, Naser; Egbert, Gary D.; Tandon, Kush
"Separations: Dust to Dust" or " You Can't Escape Em"
"SEPARATIONS: DUST TO DUST" OR "YOU CAN'T ESCAPE EM" Robert G. Massey Office of Industrial Programs U.S. Dept. of Energy ABSTRACT Separations are recognized by industry as one of the larger, if not the largest, energy using processes..."SEPARATIONS: DUST TO DUST" OR "YOU CAN'T ESCAPE EM" Robert G. Massey Office of Industrial Programs U.S. Dept. of Energy ABSTRACT Separations are recognized by industry as one of the larger, if not the largest, energy using processes...
Massey, R. G.
INPE-12145-TDI/969 AN├üLISE DE EPIS├?DIOS DE TORNADO EM SANTA CATARINA: CARACTERIZA├?├?O SIN├?TICA E. An├Īlise de epis├│dios de tornados em Santa Catarina: caracteriza├¦├Żo sin├│tica e minera├¦├Żo de dados / I. P. O(meteorologia). 3.Meteorologia sin├│tica. 4.Imagem de sat├®lite. 5.Minera├¦├Żo de dados. 6.Paisagem. 7.Brasil. 8.Santa
A laboratory experiment on EM backscatter from Farley-Buneman and gradient drift waves
Results of laboratory experiment on Bragg backscatter of 3-cm microwaves by turbulent waves driven by the Farley-Buneman and gradient drift instabilities are reported. It is noted that the study is the third in a series of laboratory experiments performed to test, under controlled conditions, prevalent ideas on EM scattering by equatorial and high-latitude ionospheric waves and irregularities. It is shown through separate backscattering from fast and slow ion beam modes that a beam of EM radiation actually provides, in backscatter, information on the spectral content of the scattering medium.
Alport, M. J.; Dangelo, N.; Pecseli, H. L.
Rotating-bed reactor as a power source for EM gun applications
Electromagnetic gun applications of the Rotating Bed Reactor (RBR) are examined. The RBR is a compact (approx. 1 m/sup 3/), (up to several thousand MW(th)), high-power reactor concept, capable of producing a high-temperature (up to approx. 300/sup 0/K) gas stream with a MHD generator coupled to it, the RBR can generate electric power (up to approx. 1000 MW(e)) in the pulsed or cw modes. Three EM gun applications are investigated: a rail gun thruster for orbit transfer, a rapid-fire EM gun for point defense, and a direct ground-to-space launch. The RBR appears suitable for all applications.
Powell, J.; Botts, T.; Stickley, C.M.; Meth, S.
A hybrid ML-EM algorithm for calculation of maximum likelihood estimates in semiparametric shared frailty models
This paper describes a generalised hybrid ML-EM algorithm for the calculation of maximum likelihood estimates in semiparametric shared frailty models, the Cox proportional hazard models with hazard functions multiplied by a (parametric) frailty random variable. This hybrid method is much faster than the standard EM method and faster than the standard direct maximum likelihood method (ML, Newton¢Raphson) for large samples.
Hien T. V. Vu; Matthew W. Knuiman
The Value of Bus Rapid Transit: Hedonic Price Analysis of the EmX in Eugene, Oregon
1 The Value of Bus Rapid Transit: Hedonic Price Analysis of the EmX in Eugene, Oregon Peter of the bus rapid transit (BRT) line in the Eugene area based on changes in residential property values of the EmX in Eugene. #12;2 Table of Contents I. Introduction
Oregon, University of
RelańŃo entre Ēndice de massa corporal e habilidade motora grossa em crianńas de quatro a seis anos
RESUMO Este estudo teve por objetivo verificar a relańŃo entre o desem- penho em tarefas de habilidade motora grossa com o Ēndice de massa corporal (IMC) em meninos e meninas de quatro a seis anos de idade. Para tanto, foram analisadas 27 crianńas, sendo 16 meninos e 11 meninas, com idade mķdia de 5,64 ▒ 0,67 anos. As crianńas foram
Fabrizio Zandonadi Catenassi; Inara Marques; Carina Barbiero Bastos; Luciano Basso; Enio Ricardo Vaz Ronque; Aline Mendes Gerage
A gente mora na estrada e passeia em casa: Carga Pesada, um road-movie na TV
Resumo: O artigo em questŃo volta-se para uma anßlise do programa de televisŃo Carga Pesada, exibido pela Rede Globo de TelevisŃo, distinguindo os dois perĒodos em que foi produzido e exibido - inĒcio da dķcada de 80 e atual. Trata-se de compreender quais sŃo suas influĻncias e que estratķgias de linguagens sŃo absorvidas pelo programa. Sua relańŃo com o cinema
QUANDO A HISTėRIA INVADE A CENA: O CASO VLADIMIR HERZOG (RE)SIGNIFICADO POR FERNANDO PEIXOTO EM \\
Primeiramente, deve-se ressaltar que a proposta desta pesquisa (que se encontra em estßgio inicial e que, portanto, muitos questionamentos sŃo apenas apontados neste texto) ķ uma reflexŃo sobre a encenańŃo do espetßculo teatral Ponto de Partida de Gianfrancesco Guarnieri, em 1976, no Teatro TAIB (SP), numa produńŃo de Othon Bastos Produń§es ArtĒsticas e Documenta Produń§es ArtĒsticas. Neste sentido, tais anßlises
Ludmila Sß de Freitas
Theoretical and FEM analysis of suspension and propulsion system with HTS hybrid electromagnets in an EMS Maglev model
We have been constructed a proto-type electromagnetic suspension (EMS) based maglev vehicle system. The maglev concept utilizes magnetic forces for noncontact suspension, guidance and propulsion. The suspension system with high temperature superconducting (HTS) hybrid electromagnet (EM) is composed of HTS coils and normal coils, which consume little power to keep large suspension gap. The magnetic forces realize to guide the vehicle, propel the vehicle along the guide-way and assist in braking action. The proto-type EMS-based Maglev model is designed to keep the suspension gap of 20 mm. This paper presents the theoretical analysis of the maglev vehicle based on the EMS model to obtain the designing parameters for levitation and propulsion forces. The magnetic field distributions of the electromagnetic forces with hybrid EM and propulsion stator coils are analyzed based on three dimension (3D) finite element method (FEM) analysis. From the simulation results, appropriately design parameters of the suspension, guidance and propulsion were obtained.
Chung, Y. D.; Lee, C. Y.; Jang, J. Y.; Yoon, Y. S.; Ko, T. K.
O Prof. Paulo Helene Professor Titular da Universidade de So Paulo, Educador, Pesquisador renomado e respeitado Consultor. Engenheiro Civil, EPUSP. Especialista em "Patologa de las Construcciones", Instituto
Calif├│rnia em Berkeley, USA. Consultor do Concreto de Alto Desempenho HPC utilizado no Edif├Łcio mais alto do concreto bombeado no pa├Łs. Autor do CD desenvolvido em colabora├¦├Żo com a ABCP, destinado ao projeto, Execu├¦├Żo e Controle de Estruturas de Concreto usando HPC, publicado em 1999. Em 2002 alcan├¦ou o Recorde
A Spectrum of EM-Type Mantle Endmembers (Invited)
It has been a quarter century since White (1985) and Zindler and Hart (1986) proposed that Sr-Nd-Pb isotope ratios of oceanic basalts can be described as mixtures of depleted mantle (DMM) with a limited number of enriched global endmember components (HIMU, EMI, EMII). While the global endmembers clearly represent extremes of the timing and magnitude of mantle chemical fractionation processes, it remains a matter of debate how the intermediate isotopic compositions are formed. (1) Do they represent mixtures between the limited number of global endmembers? (2) Do they reflect processes intermediate to those forming the global endmembers? (3) Does each intermediate composition OIB suite reflect a unique timing and type of geochemical differentiation that forms its mantle source? Each possibility has important geodynamic implications. The EarthÆs mantle continuously undergoes chemical fractionation through partial melting during crust formation, and remixing through plate tectonic recycling and convection, suggesting variable timing and compositions of mantle sources forming OIB. However, such sources are likely composed of mixed lithologies (e.g. depleted peridotite and more enriched pyroxenite) and thus even extreme melt compositions might reflect mixtures of even more extreme compositions, possibly representing the global endmembers. We further address these questions based on two examples. Grande Comore Island is located on ca. 140 Ma Indian Ocean lithosphere and its lavas reflect plume-lithosphere interaction. The Grande Comore plume component has Sr-Nd-Pb isotopic compositions intermediate between HIMU and EMI, but its Os isotope ratios are extreme and among the highest measured in OIB shield building lavas. This further supports the presence of generally high Os isotope ratios in EMI and HIMU compositions. Globally in OIB, high Os isotope ratios do not correlate with lithospheric thickness, implying that high Os isotopes are not solely controlled by melt dynamics, but require variable proportions of pyroxenite/peridotite in individual OIB sources. Moreover, new isotope data from the second example, the Discovery Seamounts in the South Atlantic, reveal a continuum of compositions between the extreme EMI composition of Walvis Ridge DSDP 525A and the LOMU extreme of anomalous South Atlantic MORB related to the Discovery hotspot (Douglass et al., 1999). These compositional extremes require a range of enriched mantle compositions outside the mixing tetrahedron of the global endmembers. In the global context, each OIB suite with EM affinity appears to form a trend towards its own unique enriched mantle endmember, inconsistent with mixing between narrowly defined global endmembers. This wide spectrum of enriched mantle endmembers is consistent with a dynamic Earth that is continuously recycling varying proportions of oceanic crust and depleted peridotite, plus sediment and lower continental crust. Douglass, J., Schilling, J.-G. and Fontignie, D., 1999. J. Geophys. Res., 104: 2941-2962. White, W.M., 1985. Geology, 13: 115-118. Zindler, A. and Hart, S., 1986. Ann. Rev. Earth Planet. Sci., 14: 493-571.
Class, C.; Goldstein, S. L.; Shirey, S. B.; Le Roex, A. P.; O'Connor, J. M.; Jokat, W.
Schwannoma do nervo vestibular (neurinoma do acustico) : diagnostico e tratamento com variańŃo da abordagem cirurgica.
??O autor apresenta um estudo descritivo-retrospectivo, envolvendo 240 pacientes portadores de Schwannoma do Vestibular (SV) que foram operados em dec·bito dorsal (posińŃo de mast¾ide), monitorizadosģ (more)
Arquimedes Cavalcante Cardoso
Effects of manual chest compression and decompression in patients receiving mechanical ventilation.
??INTRODUŪ├O: Os pacientes internados em Unidades de Terapia Intensiva (UTI) que necessitam de ventilańŃo mecŌnica (VM) estŃo mais susceptĒveis ao desenvolvimento de complicań§es respirat¾rias, principalmenteģ (more)
Fabiana Della Via
Respostas posturais Ó perturbańŃo externa inesperada em judocas de diferentes nĒveis de habilidade
RESUMO O jud¶ ķ uma modalidade esportiva na qual ķ requerido o con- trole eficiente do equilĒbrio pelo atleta, por estar constantemente sujeito a movimentos inesperados impostos por seus adversßrios. Este estudo teve o objetivo de analisar as respostas posturais a uma perturbańŃo externa inesperada de judocas (n = 20) em dois nĒveis de habilidade (faixas marrom e verde) e
Sheylla Kyoko Yoshitomi; Clarice Tanaka; Marcos Duarte; Fernanda Lima; Edgard Morya; Fuad Hazime
Curso de posgraduac~ao em Astrofisica Prova de admiss~ao
, pergunta-se: qual m┬┤inima dist^ancia deve separar dois pontos sobre a superf┬┤icie lunar para que estes┬┤ermicos - = Wciclo / QA 5 #12;onde Wciclo ┬┤e o trabalho realizado em um ciclo de funcionamento do motor e QA ┬┤e
Zonation of intertidal macrobenthos in the estuaries of Schelde and Ems
Based on data, collected in 1980¢1990, the intertidal benthic macrofauna of the Schelde and Ems estuaries was compared. The spatial occurrence of the benthic macrofauna along the salinity gradient, including the freshwater tidal area was emphasized. Both estuaries appeared to have a very similar species composition, especially at genus level. The higher number of species observed in the Schelde estuary
T. Ysebaert; P. Meire; J. Coosen; K. Essink
EmNet: Satisfying The Individual User Through Empathic Home Networks: Summary
EmNet: Satisfying The Individual User Through Empathic Home Networks: Summary John R. Lange J, Empathic Systems, Human Factors 1. INTRODUCTION Increasingly, computer systems and networks are used to run. Measuring individual user sat- isfaction online and then using such measurements directly in the control
Dinda, Peter A.
Serological (Em2-ELISA) and parasitological examinations of fox populations for Echinococcus multilocularis infections.
Serum or body fluid samples of 1,006 foxes were investigated in an ELISA for antibodies against a highly sensitive and specific antigen (Em2-antigen) of Echinococcus multilocularis. Parasitological examinations of the intestines and simultaneous serological examinations were carried out in 505 foxes: A group of 98 blue foxes (Alopex lagopus) from Norwegian fox farms did not contain intestinal stages of E. multilocularis and was clearly sero-negative in Em2-ELISA. On the other hand in red foxes (Vulpes vulpes) originating from European areas known to be endemic for E. multilocularis the following average prevalence rates were found: 244 foxes from Southern Germany, E. multilocularis prevalence 55% and sero-prevalence 60%; 139 foxes from Austria, E. multilocularis prevalence 4% and sero-prevalence 12%. Serological identification of individual foxes with or without intestinal E. multilocularis infection was not possible. Only serological (no parasitological) examination in 402 foxes originating from endemic areas in Switzerland resulted in a sero-prevalence rate of 37%. Sero-prevalence was only 6% and 4% in 54 and 26 other foxes, respectively, originating from Swiss and German areas where E. multilocularis has not yet been reported. Negative control Norwegian (farmed) silver foxes (n = 43) were all sero-negative. The specificity of the Em2-ELISA was confirmed by negative Em2-serologies with sera from dogs infected with intestinal and tissue dwelling helminth species (with the exception of two from 24 dogs infected with E. granulosus).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1858455
Gottstein, B; Deplazes, P; Eckert, J; M³ller, B; Schott, E; Helle, O; Boujon, P; Wolff, K; Wandeler, A; Schwiete, U
Dendrite Tracking in Microscopic Images using Minimum Spanning Trees and Localized E-M
Dendrite Tracking in Microscopic Images using Minimum Spanning Trees and Localized E-M Fran properties of the complete set of dendrites. The optimal tree is obtained with a modified minimum such as Neurolucida1, Imaris2 or Metamorph3 provide with pow- erful interfaces to reconstruct dendritic trees
Fleuret, Fran├¦ois
Convergence results for the EM approach to mixtures of experts architectures \\Lambda
Head: Convergence results for mixtures of experts *Address for correspondence: Michael I. Jordan, E10 to support an Initiative in Intelligent Control at MIT. Michael I. Jordan is a NSF Presidential YoungConvergence results for the EM approach to mixtures of experts architectures \\Lambda Michael I
Jordan, Michael I.
A spectral domain approach to modelling of EM scattering for Synthetic Aperture Radar target recognition
A Fourier-based technique for electromagnetic (EM) wave reconstruction with application to polarimetric airborne and spaceborne radar data exploitation is presented. The method is different from conventional modelling techniques for Synthetic Aperture Radar (SAR) applications as a result of the full electromagnetic treatment of field interactions with the scatterer, the possibility of introducing new and controllable feature classes for target classification,
R. Sabry; P. W. Vachon
www.energy.psu.edu The EMS Energy Institute at Penn State is a leading research
www.energy.psu.edu The EMS Energy Institute at Penn State is a leading research and development organization focused on energy science and engineering. We are committed to: -- Providing academic and technical leadership in the development and assessment of energy technologies, -- Providing Penn State
Lee, Dongwon
Magnetic Properties of the Basalt in Hole EM 7, Mohole Project
The average direction of the remanent magnetization of the basalt layer at the bottom of hole EM 7 is inclined 36 ° above tile horizontal, indicating that the layer is reversely magnetized. Detailed demagnetization experiments with alternating magnetic fields to 800 oer- steds peak intensity indicate that the drilling operations did not remagnetize the basalts. The natural magnetization is extremely
Allan Cox; Richard R. Doell
A row-action alternative to the EM algorithm for maximizing likelihood in emission tomography
The maximum likelihood (ML) approach to estimating the radioactive distribution in the body cross section has become very popular among researchers in emission computed tomography (ECT) since it has been shown to provide very good images compared to those produced with the conventional filtered backprojection (FBP) algorithm. The expectation maximization (EM) algorithm is an often-used iterative approach for maximizing the
Jolyon Browne; Alvaro R. De Pierro
Monte Carlo EM for Generalized Linear Mixed Models using Randomized Spherical Radial
Monte Carlo EM for Generalized Linear Mixed Models using Randomized Spherical Radial Integration by Monte Carlo methods. However, in practice, the Monte Carlo sample sizes required for convergence for such methods. One solution is to use Monte Carlo approximation, as proposed by Wei and Tanner (1990
Booth, James
RESUMO Ś O presente trabalho trata das espķcies de Arales ocorrentes em lagoas de uma ßrea do semi-ßrido baiano. A ordem apresenta, no local, duas famĒlias com cinco espķcies: Lemna valdiviana Phil., Lemna aequinoctialis Welwitsch, Wolffiella lingulata (Hegelm.) Hegelm. e Wolffia columbiana Karsten (LEMNACEAE) e Pistia stratiotes L. (ARACEAE). PALAVRAS-CHAVE: Arales; plantas aqußticas; Lemnaceae; Araceae. ABSTRACT Ś This paper presents
Mßrcia Gonńalves Bezerra; Flßvio Franńa
Dynamic partnership: A new approach to EM technology commercialization and deployment
The task of restoring nuclear defense complex sites under the U.S. Department of Energy (DOE) Environmental Management (EM) Program presents an unprecedented challenge to the environmental restoration community. Effective and efficient cleanup requires the timely development or modification of novel cleanup technologies applicable to radioactive wastes. Fostering the commercialization of these innovative technologies is the mission of EM-50, the EM Program Office of Science and Technology. However, efforts are often arrested at the {open_quotes}valley of death,{close_quotes} the general term for barriers to demonstration, commercialization, and deployment. The Energy & Environmental Research Center (EERC), a not-for-profit, contract-supported organization focused on research, development, demonstration, and commercialization (RDD&C) of energy and environmental technologies, is in the second year of a cooperative agreement with the U.S. Department of Energy (DOE) Morgantown Energy Technology Center (METC) designed to deliver EM technologies into the commercial marketplace through a unique combination of technical support, real-world demonstration, and brokering. This paper profiles this novel approach, termed {open_quotes}Dynamic Partnership,{close_quotes} and reviews the application of this concept to the ongoing commercialization and deployment of four innovative cleanup technologies. 2 tabs.
Daly, D.J.; Erickson, T.A.; Groenewold, G.H. [and others
Are you under stress in EMS. Understanding the slippery slope of burnout and PTSD.
Burnout and PTSD are closely linked and often underreported in EMS. EMS classrooms do little or nothing to prepare providers for the inherent emotional stresses of emergency response and the "thick skin" culture of EMS may make many providers apprehensive about sharing their true feelings. Burnout is triggered by many of the same stresses that lead to the symptoms of PTSD and providers experiencing burnout that doesn't resolve within a few weeks may actually be experiencing PTSD. Be mindful of yourself and your fellow coworkers, particularly after a very traumatic response. And remember traumatic responses don't need to be as dramatic as Sept. 11, New Orleans after Hurricane Katrina or the Aurora, CO shootings to bother an EMS worker. In contrast, these are the calls where providers often receive the most attention. Instead, watch for the new father who just performed CPR on an infant the same age as his own, or the provider who just watched his or her friend die following a motor vehicle collision. Pay attention to yourself and colleagues, and be responsible and honest with yourself and others about when coping strategies are enough, and when they aren't. Finally, don't ever be afraid to seek help. PMID:23097838
Collopy, Kevin T; Kivlehan, Sean M; Snyder, Scott R
The heavy-tailed Multivariate Normal Inverse Gaussian (MNIG) distribution is a recent variance-mean mixture of a multivariate Gaussian with a univariate inverse Gaussian distribution. Due to the complexity of the likelihood function, parameter estimation by direct maximization is exceedingly difficult. To overcome this problem, we propose a fast and accurate multivariate Expectation- Maximization (EM) algorithm for maximum likelihood estimation of the
Tor Arne žigÕrd; Alfred Hanssen; Roy Edgar Hansen
Review Article Abstract: Many plant species abort a large fraction of their em-
Review Article Abstract: Many plant species abort a large fraction of their em- bryos. It has often abort- ed. Such selective embryo abortion would lead to investment of resources only in the offspring with the highest potential fit- ness. Many studies have shown that otherwise viable embryos are aborted. However
Klinkhamer, Peter
A very accurate design of monolithic inductors in a 2D EM simulator
This work discusses a strategy for the design of monolithic inductors through 2D EM simulations. Two different types of inductors are considered which were fabricated in a high frequency bipolar silicon process. The first type is an inductor on a traditional substrate with a solid n+-doped buried layer, the second type is an inductor on a substrate with an oxide
Egidio Ragonese; Giovanni Girlando; Giuseppe Palmisano
An EM Algorithm for Maximum Likelihood Estimation of Process Factor Analysis Models
In this dissertation, an Expectation-Maximization (EM) algorithm is developed and implemented to obtain maximum likelihood estimates of the parameters and the associated standard error estimates characterizing temporal flows for the latent variable time series following stationary vector ARMA processes, as well as the parameters defining theģ
Lee, Taehun
Relativistic MHD in dynamical spacetimes: Improved EM gauge condition for AMR grids
We recently developed a new general relativistic magnetohydrodynamic code with adaptive mesh refinement that evolves the electromagnetic (EM) vector potential (A) instead of the magnetic fields directly. Evolving A enables one to use any interpolation scheme on refinement level boundaries and still guarantee that the magnetic field remains divergenceless. As in classical EM, a gauge choice must be made when evolving A, and we chose a straightforward "algebraic" gauge condition to simplify the A evolution equation. However, magnetized black hole-neutron star (BHNS) simulations in this gauge exhibit unphysical behavior, including the spurious appearance of strong magnetic fields on refinement level boundaries. This spurious behavior is exacerbated when matter crosses refinement boundaries during tidal disruption of the NS. Applying Kreiss-Oliger dissipation to the evolution of the magnetic vector potential A slightly weakens this spurious magnetic effect, but with undesired consequences. We demonstrate via an eigenvalue analysis and a numerical study that zero-speed modes in the algebraic gauge, coupled with the frequency filtering that occurs on refinement level boundaries, are responsible for the creation of spurious magnetic fields. We show that the EM Lorenz gauge exhibits no zero-speed modes, and as a consequence, spurious magnetic effects are quickly propagated away, allowing for long-term, stable magnetized BHNS evolutions. Our study demonstrates how the EM gauge degree of freedom can be chosen to one's advantage, and that for magnetized BHNS simulations the Lorenz gauge constitutes a major improvement over the algebraic gauge.
Zachariah B. Etienne; Vasileios Paschalidis; Yuk Tung Liu; Stuart L. Shapiro
Improvement of coverage and utilization of EmOC services in southwestern Bangladesh
ObjectiveThe Government of Bangladesh has implemented safe motherhood programs throughout the country supported by the United Nations Children's Fund (UNICEF) and United Nations Population Fund (UNFPA) aimed at reducing maternal morbidity and mortality. The objective of this study is to assess the effect of the interventions on the UN emergency obstetric care (EmOC) process indicators in Khulna division, Bangladesh.
M. T. Islam; M. M. Hossain; M. A. Islam; Y. A. Haque
An EM Approach for Poisson-Gaussian Noise Modeling Anna Jezierska
the associated Poisson process is nonstationary in space and also exhibits an exponential decay in time, whereas the parameters of a probability distribution constitutes a fundamental task in many statistical signal processingAn EM Approach for Poisson-Gaussian Noise Modeling Anna Jezierska , Caroline Chaux, Jean
Boyer, Edmond
Quality Control of CNT Forests via EM Probing Tianyou Kou, C. Emre Koksal, and Eylem Ekici
, especially for flat-panel displays. During the process of growing the CNT forests, it is highly probable. Rather than relying on the oscillation of electrons inside the antenna in response to EM waves, CNTs was first proposed in [1] to use CNTs as non- traditional antennas to receive RF signals, further analyzed
Koksal, Can Emre
The St em Cell and Regenerat ive Medicine Cent er Post doct oral Fellowships
The St em Cell and Regenerat ive Medicine Cent er Post doct oral Fellowships I. General Information and highlights the significance of the work in stem cell biology and/or regenerative medicine (1 page). #12;III: Address Line #2: City: State: Zip Code: Country: Racial/Ethnic Heritage (optional): American Indian
Concepń§es de policiais sobre crianńas em situańŃo de rua: um estudo sobre preconceito
Resumo O objetivo deste estudo foi investigar a concepńŃo que policiais militares tĻm das crianńas em situańŃo de rua. Pela tķcnica da inserńŃo ecol¾gica, doze policiais homens foram selecionados ao acaso e entrevistados nas ruas perante um roteiro prķ-estabelecido. Foi realizada uma anßlise qualitativa do conte·do das entrevistas e de dißrios de campo dos pesquisadores. Os critķrios utilizados pelos policiais
Elder Cerqueira-Santos; SĒlvia H. Koller; Christian Pilz; Daniela D. Dias; Flßvia Wagner
ISO 14000 is considered a newcomer in the environmental management systems, but it is gradually gaining worldwide acceptance (10,000 certificates by June 1999). Although the food industry was not one of the first industrial sectors to implement EMS\\/ISO 14000, recent surveys in industrialized countries show that more than 1000 food companies worldwide have already applied the ISO 14001. The popular
Ioannis D. Boudouropoulos; Ioannis S. Arvanitoyannis
The VLF-EM imaging of potential collapse on the LUSI embankment
Collapse and overtopping repeatedly occur in LUSI Embankment. Discontinuities (crack or fracture) in the embankment are major reasons for embankment failures or collapses. Very-low frequency electromagnetic (VLF-EM) measurement is essentially a non-destructive technique which displays subsurface 2-D cross section of resistivity. The cross section result has the possibility of detecting discontinuities and liquid saturation in embankment before it collapsed by observing which part of it in the cross section has low resistivity. This paper presents results of a survey conducted at the LUSI embankment in Eastern Java, Indonesia in a part of potential collapse. VLF-EM profiles measured along the embankment crest provided an overview of the whole embankment and served to detect anomalous zones. The noise assisted multivariate empirical mode decomposition (NA-MEMD) is applied to reject unwanted VLF-EM noise and Inv2DVLF software is applied to obtain result of 2-D resistivity models. In the selected area, the drill log and the standard penetration test (SPT) value gave detailed information about subsurface layer below embankment. This information is valuable for supporting 2-D resistivity image obtained from VLF-EM data inversion. Furthermore, the low resistivity in embankment layer is associated to discontinuities (fracture, crack or fault) along the embankment which caused its collapse.
Sungkono; Husein, Alwi; Prasetyo, Hardi; Bahri, Ayi S.; Monteiro Santos, Fernando A.; Santosa, Bagus J.
Accelerated Iterative Reconstruction for Positron Emission Tomography Based on the EM Algorithm for Maximum Likelihood Estimation
The EM method that was originally developed for maximum likelihood estimation in the context of mathematical statistics may be applied to a stochastic model of positron emission tomography (PET). The result is an iterative algorithm for image reconstruction that is finding increasing use in PET, due to its attractive theoretical and practical properties. Its major disadvantage is the large amount
Robert M. Lewitt; Gerd Muehllehner
Resumo - Este trabalho apresenta um sistema de posicionamento automßtico para painķis fotovoltaicos, com o objetivo de melhorar a conversŃo da energia solar em energia elķtrica. Um prot¾tipo com movimentańŃo automßtica foi desenvolvido e sua eficiĻncia na gerańŃo de energia foi comparada a outro sistema com as mesmas caracterĒsticas, porķm fixo. Resultados obtidos demonstram um aumento significativo na eficiĻncia, obtido
Alceu F. Alves; Josķ A. Cagnon; Josķ R. C. P. Fraga
Environmental Cost Analysis System (ECAS) Status and Compliance Requirements for EM Consolidated Business Center Contracts - 13204
The Department of Energy (DOE) Office of Environmental Management (EM) has developed a web-accessible database to collect actual cost data from completed EM projects to support cost estimating and analysis. This Environmental Cost Analysis System (ECAS) database was initially deployed in early 2009 containing the cost and parametric data from 77 decommissioning, restoration, and waste management projects completed under the Rocky Flats Closure Project. In subsequent years we have added many more projects to ECAS and now have a total of 280 projects from 8 major DOE sites. This data is now accessible to DOE users through a web-based reporting tool that allows users to tailor report outputs to meet their specific needs. We are using it as a principal resource supporting the EM Consolidated Business Center (EMCBC) and the EM Applied Cost Engineering (ACE) team cost estimating and analysis efforts across the country. The database has received Government Accountability Office review as supporting its recommended improvements in DOE's cost estimating process, as well as review from the DOE Office of Acquisition and Project Management (APM). Moving forward, the EMCBC has developed a Special Contract Requirement clause or 'H-Clause' to be included in all current and future EMCBC procurements identifying the process that contractors will follow to provide DOE their historical project data in a format compatible with ECAS. Changes to DOE O 413.3B implementation are also in progress to capture historical costs as part of the Critical Decision project closeout process. (authors)
Sanford, P.C. [Consultant, 11221 E. Cimmarron Dr., Englewood, CO 80111 (United States)] [Consultant, 11221 E. Cimmarron Dr., Englewood, CO 80111 (United States); Moe, M.A. [EMCBC Office of Cost Estimating and Analysis, United States Department of Energy, 250 E. 5th Street, Suite 500, Cincinnati, OH 45202 (United States)] [EMCBC Office of Cost Estimating and Analysis, United States Department of Energy, 250 E. 5th Street, Suite 500, Cincinnati, OH 45202 (United States); Hombach, W.G. [Team Analysis, Inc., 2 Cardinal Park Drive, Suite 105A, Leesburg, VA 20175 (United States)] [Team Analysis, Inc., 2 Cardinal Park Drive, Suite 105A, Leesburg, VA 20175 (United States); Urdangaray, R. [Project Performance Corporation, 1760 Old Meadow Road, McLean, VA 22102 (United States)] [Project Performance Corporation, 1760 Old Meadow Road, McLean, VA 22102 (United States)
"Science affects the way we think together." SEEN ONE DAM, SEEN `EM ALL?
debate about removal of dams from the Columbia and Snake Rivers, an interesting twist emerges from"Science affects the way we think together." SEEN ONE DAM, SEEN `EM ALL?: THE SURPRISING STORY of private dams will be relicensed by the Federal Energy Regulatory Commission. Many of them
PEDRO ALMODėVAR ANALISTA DE SI MESMO?1 A movida madrile±a em \\
Resumo: Este artigo analisa as primeiras produń§es cinematogrßficas de Pedro Almod¾var identificadas ao movimento artĒstico-cultural denominado de movida madrilena. Busca-se relacionar o que Pierre Bourdieu chama em seu livro As Regras da Arte de visŃo soci¾loga do escritor francĻs Gustave Flaubert, construĒda na obra A educańŃo sentimental, com a hip¾tese de o cineasta espanhol Pedro Almod¾var tambķm se revelar um
Meize Regina de Lucena; Gustavo Colares; Melo Carlos
Em busca da caixa mßgica: o Estado Novo e a televisŃo
RESUMO A anßlise hist¾rica sobre a ExposińŃo de TelevisŃo (Rio de Janeiro, 1939), evento promovido pelo Estado Novo em parce- ria com o Terceiro Reich alemŃo, permi- te trazer, alķm de dados sobre a hist¾ria da TV no Brasil, elementos de compreen- sŃo sobre as primeiras relań§es entre po- der polĒtico e esse meio de comunicańŃo no paĒs. Pois, a
┴ureo Busetto
Responsabilidade Civil do Construtor e sua AplicańŃo em Auditoria de Obras P·blicas
Em auditorias de obras p·blicas, diversos fatores que podem implicar a mß qualidade e pouca durabilidade do trabalho nŃo podem ser efetivamente verificados. Diversos problemas, tais quais: mß qualidade de materiais, mß qualidade de mŃo- de-obra e inadequańŃo de projetos, que adversamente afetarŃo a qualidade da obra, a sua durabilidade e a sua funcionalidade, dificilmente podem ser constatados durante as
Carnot Leal Nogueira
Estimating Word Translation Probabilities from Unrelated Monolingual Corpora Using the EM Algorithm
Selecting the right word translation among several op- tions in the lexicon is a core problem for machine trans- lation. We present a novel approach to this problem that can be trained using only unrelated monolingual corpora and a lexicon. By estimating word translation probabilities using the EM algorithm, we extend upon target language modeling. We construct a word trans-
Philipp Koehn; Kevin Knight
Laboratory experiment on EM backscatter from Farley-Buneman and gradient drift waves
Results are reported of a laboratory experiment on Bragg backscatter of 3-cm microwaves by turbulent waves driven by the Farley-Buneman and gradient drift instabilities. The present work is the third in a series of laboratory experiments performed to test, under controlled conditions, prevalent ideas on EM scattering equatorial and high-latitude ionospheric waves and irregularities.
Alport, M.J.; D'Angelo, N.; Pecseli, H.L.
G EM OF HI E MO UNTA I S 2 (piece by pieee)
#12;#12;#12;#12;I ) #12;G EM OF HI E MO UNTA I S 2 (piece by pieee) student life academics #12;GEM and players alike motivated for the upcoming football game. ABOVE- Joe Vandal rings the bell in celebration people on the stage, and no pre-recorded music. FAR, LEFT - Onlookers clap as the Ul marching band
O'Laughlin, Jay
De-centralized and centralized control for realistic EMS Maglev systems
A comparative study of de-centralized and centralized controllers when used with real EMS Maglev Systems is introduced. This comparison is divided into two parts. Part I is concerned with numerical simulation and experimental testing on a two ton six-magnet EMS Maglev vehicle. Levitation and lateral control with these controllers individually and when including flux feedback control in combination with these controllers to enhance stability are introduced. The centralized controller is better than the de-centralized one when the system is exposed to a lateral disturbing force such as wind gusts. The flux feedback control when combined with de-centralized or centralized controllers does improve the stability and is more resistant and robust with respect to the air gap variations. Part II is concerned with the study of Maglev vehicle-girder dynamic interaction system and the comparison between these two controllers on this typical system based on performance and ride quality achieved. Numerical simulations of the ODU EMS Maglev vehicle interacting with girder are conducted with these two different controllers. The de-centralized and centralized control for EMS Maglev systems that interact with a flexible girder provides similar ride quality. Centralized control with flux feedback could be the best controller for the ODU Maglev system when operating on girder. The centralized control will guarantee the suppression of the undesired lateral displacements; hence it will provide smoother ride quality. Flux feedback will suppress air gap variations due to the track discontinuities.
Moawad, Mohamed M. Aly M.
A caminho do topo Criar em Portugal uma universidade de dimenso mdia no plano europeu,
Lisboa (a antiga "Cl'┐Įssica") e T'┐Įcnica de Lisboa teve o objetivo de criar uma nova institui'┐Į'┐Įo: a maior (a antiga "Cl'┐Įssica") com a Universidade T'┐Įcnica de Lisboa. Que cuidados foram necess'┐Įrios ter em
External Resource: Earth-Moon-Sun Dynamics: Building the EMS Model
In this unit of study, students participate in iterative model building as they encounter patterns in various celestial phenomena and attempt to provide a causal explanation for them. Each of the six materials within Building the EMS Model focuses on a di
Precision and accuracy of regional radioactivity quantitation using the maximum likelihood EM reconstruction algorithm
The imaging characteristics of maximum likelihood (ML) reconstruction using the EM algorithm for emission tomography have been extensively evaluated. There has been less study of the precision and accuracy of ML estimates of regional radioactivity concentration. The authors developed a realistic brain slice simulation by segmenting a normal subject's MRI scan into gray matter, white matter, and CSF and produced
Richard E. Carson; Yuchen Yan; BettyAnn Chodkowski; Tieng K. Yap; Margaret E. Daube-Witherspoon
UFF/PROGEPE/CASQ/DPVS Diviso de Promoo e Vigilncia em Sade-DPVS
fumantes sendo 47% homens e 12% mulheres. No Brasil, em pesquisa recente do INCA/MS, os dados apontaram para 18,8% da popula├¦├Żo brasileira como fumante, sendo 22,7% homens e 16% mulheres. Tamb├®m no Brasil
Souza, Max O.
Longer term impacts of transformed courses on student conceptual understanding of E&M
We have measured upper-division physics majors' performance using two research-based conceptual instruments in E&M, the BEMA and the CUE (Colorado Upper Division Electrostatics assessment.) The BEMA has been given pre/post in freshman E&M (Physics II) courses, and the BEMA and CUE have been given pre/post in several upper-division E&M courses. Some of these data extend over 10 semesters. We used PER-based techniques to transform the introductory and upper-division courses starting in Fall 2004 and 2007, respectively. Our longitudinal data allow us to measure "fade" on BEMA performance between freshman and junior year. We investigate the effects of curricula on students by comparing juniors who were enrolled in traditional vs. transformed physics as freshmen, as well as those who were enrolled in traditional or transformed upper-division E&M I, using both BEMA and CUE measures. We find that while freshman reforms significantly impact BEMA scores, junior-level reforms affect CUE but not BEMA outcomes.
EM+TV for Reconstruction of Cone-beam CT with Curved Detectors using GPU
EM+TV for Reconstruction of Cone-beam CT with Curved Detectors using GPU Jianwen Chen, Ming Yan with CT is significant. Methods that can enable CT imaging at reduced radiation exposure without improved reconstruction at lower radiation exposure levels. The method is based on the combination of 1
Cong, Jason "Jingsheng"
Crosshole EM for oil field characterization and EOR monitoring: Field examples from Lost Hills, California
A steamflood recently initiated by Mobil Development and Production U.S. at the Lost Hills No 3 oil field in California is notable for its shallow depth and the application of electromagnetic (EM) geophysical techniques to monitor the subsurface steam flow. Steam was injected into three stacked eastward-dipping unconsolidated oil sands at depths from 60 to 120 m; the plume is
Michael Wilt; Clifford Schenkel; Michael Wratcher; Ilia Lambert; Carlos Torres-Verdin; Tseng H. W
Color fusion based on EM algorithm for IR and visible image
As two of the most commonly used image sensors in night-vision for military applications, infrared (IR) and visible light cameras have their own advantages and limitations due to the physical differences between the image formation processes. In this paper, a new multi-scale scheme for color image fusion is presented using EM algorithm and color transfer algorithm for IR and visible
Gang Liu; Guohong Huang
Data for Environmental Modeling (D4EM): Background and Applications of Data Automation
The Data for Environmental Modeling (D4EM) project demonstrates the development of a comprehensive set of open source software tools that overcome obstacles to accessing data needed by automating the process of populating model input data sets with environmental data available fr...
Nonorthogonal PEEC formulation for time- and frequency-domain EM and circuit modeling
Electromagnetic solvers based on the partial element equivalent circuit (PEEC) approach have proven to be well suited for the solution of combined circuit and EM problems. The inclusion of all types of Spice circuit elements is possible. Due to this, the approach has been used in many different tools. Most of these solvers have been based on a rectangular or
Albert E. Ruehli; Giulio Antonini; Joris Esch; Jonas Ekman; Anita Mayo; Antonio Orlandi
Reduction of EMI for oblique incidence of em waves Ś A case study
Reducti on of Electromagnetic Interference (EM I), i.e., shielding effectiveness of different shields against the angle of incidence with conductors and conductive polymers using planeŁ wave theory are carried out. The plane wave shielding effectiveness of new combination of these materials is evaluated as a function of angle of incidence for the single shield. With recent advancements in synthesizing stable
K Brahmananda Reddy; JVS Srikanth Prasad; Ande Srikanth; K Ajit Kishan
KEY AND SUPPLEMENTARY COMPARISONS: RMO comparison final report: 2006-2007 Resistance standards comparison between SIM laboratories. SIM.EM-K1, 1 ? SIM.EM-K2, 1 G? SIM.EM-S6, 1 M?
The Working Group for Electricity and Magnetism of the Inter-American Metrology System (SIM) initiated the key and supplemental regional comparisons SIM.EM-K1-K2-S6 to provide the first internationally recognized comparisons of precision resistance measurements for nations of the western hemisphere. These comparisons include the official metrology institutes of six members of SIM and follow the guidelines for key comparisons under the 1999 CIPM Mutual Recognition Arrangement (MRA). The National Institute of Standards and Technology (NIST) provided the comparison standards and acted as the pilot laboratory in the SIM.EM-K1-K2-S6 comparisons, which began in January 2006 and were completed in September 2007. By means of procedures for linking key comparison data, the SIM.EM-K1-K2 comparisons will help to provide assurance of equality in measurements between the nations organized in SIM and the participants in the CCEM key comparisons. The analysis included in this report (Appendix A) specifically provides methods for calculating the degrees of equivalence and their uncertainties between the national measurement standards of the participating laboratories (Appendix B). A subsequent analysis (Appendix G) provides methods and results linking this regional comparison to CCEM key comparison CCEM-K2 and a recent BIPM-NIST bilateral comparison at the 1 ? level. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Elmquist, R. E.; Jarrett, D. G.; Zhang, N. F.
Cramer-Rao lower bound optimization of an EM-CCD-based scintillation gamma camera
Scintillation gamma cameras based on low-noise electron multiplication (EM-)CCDs can reach high spatial resolutions. For further improvement of these gamma cameras, more insight is needed into how various parameters that characterize these devices influence their performance. Here, we use the Cramer-Rao lower bound (CRLB) to investigate the sensitivity of the energy and spatial resolution of an EM-CCD-based gamma camera to several parameters. The gamma camera setup consists of a 3 mm thick CsI(Tl) scintillator optically coupled by a fiber optic plate to the E2V CCD97 EM-CCD. For this setup, the position and energy of incoming gamma photons are determined with a maximum-likelihood detection algorithm. To serve as the basis for the CRLB calculations, accurate models for the depth-dependent scintillation light distribution are derived and combined with a previously validated statistical response model for the EM-CCD. The sensitivity of the lower bounds for energy and spatial resolution to the EM gain and the depth-of-interaction (DOI) are calculated and compared to experimentally obtained values. Furthermore, calculations of the influence of the number of detected optical photons and noise sources in the image area on the energy and spatial resolution are presented. Trends predicted by CRLB calculations agree with experiments, although experimental values for spatial and energy resolution are typically a factor of 1.5 above the calculated lower bounds. Calculations and experiments both show that an intermediate EM gain setting results in the best possible spatial or energy resolution and that the spatial resolution of the gamma camera degrades rapidly as a function of the DOI. Furthermore, calculations suggest that a large improvement in gamma camera performance is achieved by an increase in the number of detected photons or a reduction of noise in the image area. A large noise reduction, as is possible with a new generation of EM-CCD electronics, may improve the energy and spatial resolution by a factor of 1.5.
Korevaar, Marc A. N.; Goorden, Marlies C.; Beekman, Freek J.
Cramer-Rao lower bound optimization of an EM-CCD-based scintillation gamma camera.
Scintillation gamma cameras based on low-noise electron multiplication (EM-)CCDs can reach high spatial resolutions. For further improvement of these gamma cameras, more insight is needed into how various parameters that characterize these devices influence their performance. Here, we use the Cramer-Rao lower bound (CRLB) to investigate the sensitivity of the energy and spatial resolution of an EM-CCD-based gamma camera to several parameters. The gamma camera setup consists of a 3Āmm thick CsI(Tl) scintillator optically coupled by a fiber optic plate to the E2V CCD97 EM-CCD. For this setup, the position and energy of incoming gamma photons are determined with a maximum-likelihood detection algorithm. To serve as the basis for the CRLB calculations, accurate models for the depth-dependent scintillation light distribution are derived and combined with a previously validated statistical response model for the EM-CCD. The sensitivity of the lower bounds for energy and spatial resolution to the EM gain and the depth-of-interaction (DOI) are calculated and compared to experimentally obtained values. Furthermore, calculations of the influence of the number of detected optical photons and noise sources in the image area on the energy and spatial resolution are presented. Trends predicted by CRLB calculations agree with experiments, although experimental values for spatial and energy resolution are typically a factor of 1.5 above the calculated lower bounds. Calculations and experiments both show that an intermediate EM gain setting results in the best possible spatial or energy resolution and that the spatial resolution of the gamma camera degrades rapidly as a function of the DOI. Furthermore, calculations suggest that a large improvement in gamma camera performance is achieved by an increase in the number of detected photons or a reduction of noise in the image area. A large noise reduction, as is possible with a new generation of EM-CCD electronics, may improve the energy and spatial resolution by a factor of 1.5. PMID:23552717
Korevaar, Marc A N; Goorden, Marlies C; Beekman, Freek J
The Distance to SN 1999em in NGC 1637 from the Expanding Photosphere Method
We present 30 optical spectra and 49 photometric epochs sampling the first 517 days after discovery of supernova (SN) 1999em, and derive its distance through the expanding photosphere method (EPM). SN 1999em is shown to be a Type II-plateau (II-P) event, with a photometric plateau lasting until about 100 days after explosion. We identify the dominant ions responsible for most of the absorption features seen in the optical portion of the spectrum during the plateau phase. We find the distance to SN 1999em to be D = 8.2 +/- 0.6 Mpc, with an explosion date of 5.3 +/- 1.4 days before discovery. We examine potential sources of systematic error in EPM-derived distances, and find the most significant to result from uncertainty in the theoretical modeling of the flux distribution emitted by the SN photosphere (i.e., the ``flux dilution factor''). We compare previously derived EPM distances to 5 SNe II in galaxies for which a recently revised Cepheid distance exists from the HST Key Project and find D(Cepheids) / D(EPM) = 0.96 +/- 0.09. Finally, we investigate the possible use of SNe II-P as standard candles and find that for 8 photometrically confirmed SNe II-P with previously derived EPM distances and SN 1999em, the mean plateau absolute brightness is M_V(plateau) = -16.4 +/- 0.6 mag, implying that distances good to ~30% (1-sigma) may be possible without the need for a complete EPM analysis. At M_V(plateau) = -15.9 +/- 0.2 mag, SN 1999em is somewhat fainter than the average SN II-P. The general consistency of absolute SNe II-P brightness during the plateau suggests that the standard candle assumption may allow SNe II-P to be viable cosmological beacons at z > 2.
Douglas C. Leonard; Alexei V. Filippenko; Elinor L. Gates; Weidong Li; Ronald G. Eastman; Aaron J. Barth; Schelte J. Bus; Ryan Chornock; Alison L. Coil; Sabine Frink; Carol A. Grady; Alan W. Harris; Matthew A. Malkan; Thomas Matheson; Andreas Quirrenbach; Richard R. Treffers
Marine EM inversion using unstructured grids and a parallel adaptive finite element method
Marine electromagnetic (EM) methods are increasingly being used for mapping tectonic structures and offshore resources. While the ability to collect dense 2D profiles and 3D grids of multi-frequency, multi-component data has grown significantly in industry and academia during the past decade, the ability to accurately and efficiently model this data remains a significant computational challenge. To date, most non-linear inversion algorithms applied for marine EM problems have relied on some form of rectangular grids for both the inversion model parameters and the finite-element (FE) or finite-difference discretization of the differential equations; often the same grid is used for both. This work explores the use of unstructured grids for two-dimensional marine EM inversion. Here the inversion minimization is based on the Occam approach but the parameterization is instead defined using arbitrarily shaped polygonal regions. Such a model discretization overcomes many of the shortcomings of rectangular grids. It readily allows for the accurate inclusion of known complex structures (e.g., seafloor bathymetry and seismic surfaces); it also allows for a more efficient model discretization since the parameter density can be concentrated (and refined) only where required. Due to the wide availability of robust triangulation algorithms, constrained conforming Delaunay triangulations are a convenient tool for generating an unstructured model discretization. The forward problem is implemented with a parallel adaptive finite element (FE) method that automatically generates an unstructured triangular FE grid that conforms to the model parameter boundaries. The FE grid is then automatically refined until the FE solution obtains an user specified tolerance. This inversion methodology has been implemented in a single code that handles both the magnetotelluric and controlled-source EM modeling problems. Along with a few synthetic examples that demonstrate the advantages of unstructured grid inversions, this algorithm is applied to a publicly available marine EM data set collected at Hydrate Ridge.
Key, K. W.
Fabrication of carbon films with ? 500nm holes for cryo-EM with a direct detector device.
Single particle electron cryomicroscopy (cryo-EM) is often performed using EM grids coated with a perforated or holey layer of amorphous carbon. Regular arrays of holes enable efficient cryo-EM data collection and several methods for the production of micropatterned holey-carbon film coated grids have been described. However, a new generation of direct detector device (DDD) electron microscope cameras can benefit from hole diameters that are smaller than currently available. Here we extend a previously proposed method involving soft lithography with a poly(dimethylsiloxane) (PDMS) stamp for the production of holey-carbon film coated EM grids. By incorporating electron-beam (e-beam) lithography and modifying the procedure, we are able to produce low-cost high-quality holey-carbon film coated EM grids with ?500nm holes spaced 4?m apart centre-to-centre. We demonstrate that these grids can be used for cryo-EM. Furthermore, we show that by applying image shifts to obtain movies of the carbon regions beside the holes after imaging the holes, the contrast transfer function (CTF) parameters needed for calculation of high-resolution cryo-EM maps with a DDD can be obtained efficiently. PMID:24269484
Marr, Chelsea R; Benlekbir, Samir; Rubinstein, John L
Emergence of vancomycin-resistant Enterococcus faecium after use of inhaled vancomycin in a cystic fibrosis patient chronically infected with methicillin-resistant Staphylococcus aureus EmergĻncia de Enterococcus faecium resistente Ó vancomicina em paciente com fibrose cĒstica e infecńŃo cr¶nica por Staphylococcus aureus resistente Ó meticilina ap¾s tratamento com vancomicina inalat¾ria
The authors describe a case of emergence of multi-resistant pathogens in a cystic fibrosis patient treated with inhaled vancomycin: A ten- year-old female patient, chronically infected with methicillin-resistant Staphylococcus aureus, presenting worsening of lung disease. She was placed on inhaled vancomycin with clinical improvement, but B. cepacia complex was isolated in sputum and vancomycin-resistant Enterococcus faecium was identified in a
Luiz Vicente; Ribeiro Ferreira da Silva Filho; Fabiola Villac Adde; Giuliana de Freitas Fongaro; Luciana Correia de Menezes; Alfio Rossi Junior; Joaquim Carlos Rodrigues
EmergĻncia de Enterococcus faecium resistente Ó vancomicina em paciente com fibrose cĒstica e infecńŃo cr¶nica por Staphylococcus aureus resistente Ó meticilina ap¾s tratamento com vancomicina inalat¾ria Emergence of vancomycin-resistant Enterococcus faecium after use of inhaled vancomycin in a cystic fibrosis patient chronically infected with methicillin-resistant Staphylococcus aureus
Prevalence of hereditary factors predisposing to thrombosis in 260 patients diagnosed as thrombosis and investigated at Hospital Israelita Albert Einstein, SŃo Paulo, Brazil PrevalĻncia de fatores hereditßrios que predisp§em Ó trombose em 260 pacientes com diagn¾stico de trombose e investigados no Hospital Israelita Albert Einstein, SŃo Paulo, Brasil
Objective: To evaluate the prevalence of genetic polymorphism in coagulation factors in thromboembolic disease in patients with clinical suspicion of thrombosis. Methods: A retrospective case collection was performed searching all patients with clinical suspicion of thrombosis who were submitted to coagulation factor analysis at the Hospital Israelita Albert Einstein from November 2003 to April 2004. We included 260 patients, 118
Campos Guerra; Marden Rene Ferreira; Claudio Albers Mendes; Valdir Aranda
A teoria do autocuidado no manejo dos fatores de risco (obesidade, hipertensŃo e tabagismo) em pacientes p¾s-infarto agudo do miocßrdio Contribution of the nurse attendance through the theory of self care in the handling of coronary risk factors (obesity, hypertension and smoking) in patient post acute myocardial infaction
Objective: To evaluate the effectiveness of reducing risk factors for established CAD, by adding a nursing program to conventional treatment based on the Theory of Self-Care. Methodology: This is a randomized clinical trial in a population consisting of 74 patients who have had a first myocardial infarction. The intervention (Group A) was a program of educational nursing actions. The control
AvaliańŃo da agregańŃo plaquetßria e dosagem do fibrinogĻnio em pacientes com doenńas cardiovasculares e sua correlańŃo com o uso de aspirina e fatores de risco coronariano Evaluation of platelet aggregation and level of fibrinogen in patients with cardiovascular diseases and the correlation of taking aspirin with coronary risk factors
Objective: To evaluate aspirin resistance in patients with cardiovascular diseases and to compare the amount of serum fibrinogen in patients taking aspirin with those who do not. To correlate the platelet aggregation and serum fibrinogen to cardiovascular risk parameters. Method: Eighty-two patients were divided into two groups: Group 1 - 41 patients who took 100mg aspirin daily and Group 2
Sthefano Atique GABRIEL; Cristiane Knopp TRIST├O; Luciana Cristante IZAR; Carolina DOMINGUES; Edmo Atique GABRIEL; Marcelo Gil CLIQUET
DeposińŃo pulmonar de tobramicina inalat¾ria antes e ap¾s fisioterapia respirat¾ria e uso de salbutamol inalat¾rio em pacientes com fibrose cĒstica colonizados por Pseudomonas aeruginosa* Pulmonary deposition of inhaled tobramycin prior to and after respiratory therapy and use of inhaled albuterol in cystic fibrosis patients colonized with Pseudomonas aeruginosa
Objective: To evaluate whether respiratory therapy followed by the use of inhaled albuterol modifies the pulmonary deposition of inhaled tobramycin in patients with cystic fibrosis (CF) and whether pulmonary deposition correlates with disease severity or genotype. Methods: A prospective study was carried out including patients with CF older than 6 years of age and colonized with Pseudomonas aeruginosa. Exclusion criteria
Milena Baptistella Grotta; Antonio Fernando Ribeiro; Juliana Romanato; Maria ┬ngela; Gonńalves de Oliveira Ribeiro; Josķ Dirceu Ribeiro
Objetivo Realizar uma anßlise da inserńŃo da ķtica e humanidades no currĒculo do Curso de Medicina da Escola Superior em CiĻncias da Sa·de - ESCS, escola p·blica do Distrito Federal, Brasil, de forma a contribuir com o processo de gestŃo curricular. Metodologia O Estudo ķ de coorte e documental. Foram pesquisados 37 termos relacionados Ó ķtica e 36 referentes Ó humanizańŃo nos objetivos educacionais e conte·do dos m¾dulos temßticos, habilidades e atitudes e interańŃo ensino-servińo-comunidade, de 1a a 4a sķrie e no programa do internato no currĒculo (ano 2006) e no projeto pedag¾gico do Curso de Medicina (2001). Resultados Maior inserńŃo da humanizańŃo, ķtica e bioķtica na 1a e 2a sķrie, quando comparado Ó inserńŃo na 3a e 4a sķrie e no internato, (IC95%-?=0,034, pvalue=0,007). Unidade de habilidades e atitudes: freq³Ļncia das 3 temßticas no currĒculo da 1a a 4a sķries (IC95%-?=0,026, pvalue=0,013). Quando comparada a inserńŃo entre o internato e as quatro primeiras sķries, observa-se que nestas a inserńŃo da temßtica humanizańŃo ķ superior (IC95%-?=0,042, pvalue=0,029). ConclusŃo O currĒculo desenvolvido no ano de 2006 na ESCS apresentou correlańŃo com o projeto pedag¾gico do curso e contemplou a temßtica de forma abrangente, em todas as sķries e internato. PMID:20396594
Novaes, Maria Rita Carvalho Garbi; Novaes, Luiz Carlos Garcez; Guilhem, Dirce; Lolas, Fernando; Silveira, Carla; Guiotti, Murilo
The U. S. Department of Energy's (DOE) Office of Environmental Management (EM) has the responsibility for cleaning up 60 sites in 22 states that were associated with the legacy of the nation's nuclear weapons program and other research and development activities. These sites are unique and many of the technologies needed to successfully disposition the associated wastes have yet to be developed or would require significant re-engineering to be adapted for future EM cleanup efforts. In 2008, the DOE-EM Engineering and Technology Program (EM-22) released the Engineering and Technology Roadmap in response to Congressional direction and the need to focus on longer term activities required for the completion of the aforementioned cleanup program. One of the strategic initiatives included in the Roadmap was to enhance long term performance monitoring as defined by 'Develop and deploy cost effective long-term strategies and technologies to monitor closure sites (including soil, groundwater, and surface water) with multiple contaminants (organics, metals and radionuclides) to verify integrated long-term cleanup performance'. To support this long-term monitoring (LTM) strategic initiative, EM 22 and the Savannah River National Laboratory (SRNL) organized and held an interactive symposia, known as the 2009 DOE-EM Long-Term Monitoring Technical Forum, to define and prioritize LTM improvement strategies and products that could be realized within a 3 to 5 year investment time frame. This near-term focus on fundamental research would then be used as a foundation for development of applied programs to improve the closure and long-term performance of EM's legacy waste sites. The Technical Forum was held in Atlanta, GA on February 11-12, 2009, and attended by 57 professionals with a focus on identifying those areas of opportunity that would most effectively advance the transition of the current practices to a more effective strategy for the LTM paradigm. The meeting format encompassed three break-out sessions, which focused on needs and opportunities associated with the following LTM technical areas: (1) Performance Monitoring Tools, (2) Systems, and (3) Information Management. The specific objectives of the Technical Forum were to identify: (1) technical targets for reducing EM costs for life-cycle monitoring; (2) cost-effective approaches and tools to support the transition from active to passive remedies at EM waste sites; and (3) specific goals and objectives associated with the lifecycle monitoring initiatives outlined within the Roadmap. The first Breakout Session on LTM performance measurement tools focused on the integration and improvement of LTM performance measurement and monitoring tools that deal with parameters such as ecosystems, boundary conditions, geophysics, remote sensing, biomarkers, ecological indicators and other types of data used in LTM configurations. Although specific tools were discussed, it was recognized that the Breakout Session could not comprehensively discuss all monitoring technologies in the time provided. Attendees provided key references where other organizations have assessed monitoring tools. Three investment sectors were developed in this Breakout Session. The second Breakout Session was on LTM systems. The focus of this session was to identify new and inventive LTM systems addressing the framework for interactive parameters such as infrastructure, sensors, diagnostic features, field screening tools, state of the art characterization monitoring systems/concepts, and ecosystem approaches to site conditions and evolution. LTM systems consist of the combination of data acquisition and management efforts, data processing and analysis efforts and reporting tools. The objective of the LTM systems workgroup was to provide a vision and path towards novel and innovative LTM systems, which should be able to provide relevant, actionable information on system performance in a cost-effective manner. Two investment sectors were developed in this Breakout Session. The last Breakout Session of the Technical Forum
Mayer, J.
F589 -QUINTA LISTA DE EXERCICIOS 1. Mostre, para um atomo de Thompson, que um eletron que esta em movimento em
F589 - QUINTA LISTA DE EXERC┬┤ICIOS 1. Mostre, para um ┬┤atomo de Thompson, que um el┬┤etron que est part┬┤icula de 5.30 MeV ┬┤e espalhada por um ^angulo de 60 graus ao passar por uma fina folha met. Mostre que a frequ^encia de rota┬Ėc~ao de um el┬┤etron em um ┬┤atomo no modelo de hidrog^enio de Bohr ┬┤e
de Aguiar, Marcus A. M.
[Evaluation of the diagnostic value of the ELISA tests developed by using EgHF, Em2 and EmII/3-10 antigens in the serological diagnosis of alveolar echinococcosis].
Alveolar echinococcosis (AE), caused by larva stage of Echinococcus multilocularis, is one of the lethal parasitic diseases of man and a major public health problem in many countries in the northern hemisphere. When the living conditions and habits in Turkey were considered in terms of relation with the life cycle of the parasite, it was suggested that AE has been much more common than reported mainly from the Eastern Anatolia region of Turkey. Since in vitro serologic diagnosis tests with high specificity for AE have not been used in our country, most of the cases with liver lesions were misdiagnosed by radiological investigations as malignancies. The aim of this study was to evaluate the diagnostic value of the in-house ELISA methods developed by using three different antigens (EgHF, Em2, EmII/3-10) in the serological diagnosis of AE. The study samples included a total of 100 sera provided by Bern University Parasitology Institute where samples were obtained from patients with helminthiasis and all were confirmed by clinical, parasitological and/or histopathological means. Ten samples from each of the cases infected by E.multilocularis, E.granulosus, Taenia solium, Wuchereria bancrofti, Strongyloides stercolaris, Ascaris lumbricoides, Toxocara canis, Trichinella spiralis, Fasciola hepatica and Schistosoma haematobium were studied. In the study, EgHF (E.granulosus hydatid fluid) antigens were prepared in our laboratory from the liver cyst fluids of sheeps with cystic echinococcosis, however Em2 (E.multilocularis metacestode-purified laminated layer) and EmII/3-10 (E.multilocularis recombinant protoscolex tegument) antigens were provided by Bern University Parasitology Institute. Flat bottom ELISA plates were covered with EgHF, Em2 and EmII/3-10 antigens in the concentrations of 2.5 Ąg, 1 Ąg and 0.18 Ąg per well, respectively, and all sera were tested by EgHF-ELISA, Em2-ELISA and EmII/3-10-ELISA methods. For each tests, the samples which were reactive above the cut-off value (mean OD of negative controls+2 SD) were accepted as positive. The sensitivity of the ELISA tests performed with EgHF, Em2 and Em2II/3-10 antigens were estimated as 100%, 90% and 90%, respectively, whereas the specificity were 63%, 91% and 91%, respectively. When Em2-ELISA and EmII/3-10-ELISA tests were evaluated together, the specificity increased to 96%. Our data indicated that the highest sensitivity (100% with EgHF-ELISA) and specificity (96% with Em2-ELISA + EmII/3-10-ELISA) for the serodiagnosis of AE can be achieved by the combined use of the ELISA tests with three different antigens. It was concluded that the early and accurate diagnosis of AE in our country which is endemic for that disease, could be supported by the use of highly specific serological tests such as Em2-ELISA ve EmII/3-10-ELISA contributing radiological data. PMID:25052112
Pekta?, Bayram; Altinta?, Nazmiye; Akpolat, Nezahat; Gottstein, Bruno
Center Publications (Updated April 2009) Kirchner SC and Faustman EM. Identifying mechanisms of developmental toxicity: Application of tools from
glutathione in methylmercury-induced toxicity in embryonic neuronal cells. Neurotoxicology. 1999: 20(5): 793 RN and Faustman EM. Human variability in mercury toxicokinetics and steady state biomarker ratios
Washington at Seattle, University of
p1 RJM 18/09/13 SE1EM11 Differentiation and Integration Part A Dr Richard Mitchell 2013
on Blackboard for module SE1EM11 where also a discussion board ask / answer questions here If lose notes, spare ┬Ł In (changing) from CD, Out to Loudspeaker Car ┬Ł driver press accelerator, velocity change gradually Aircraft
Mitchell, Richard
"AvaliańŃo clĒnica do crescimento gengival induzido por ciclosporina-A e tacrolimus em indivĒduos transplantados renais: estudo prospectivo".
??Este estudo teve como objetivos avaliar a ocorrĻncia de crescimento gengival derivado da administrańŃo de duas drogas imunossupressoras ciclosporina-A (CsA) e tacrolimus, em indivĒduos transplantadosģ (more)
Ricardo Takiy Sekiguchi
Noise models and cryo-EM drift correction with a direct-electron camera
Blurring due to specimen-holder drift is a common occurrence in cryo-EM images. Cameras employing active-pixel sensors are capable of high frame rates such that a single low-dose exposure can be acquired as a series of frames. In this paper we consider the possibility of tracking and compensating for overall drift in typical single-particle specimens through the analysis of frame sequences. A problem that arises in tracking through cross-correlation of frames obtained with the DE-12 camera from Direct Electron LLC is the presence of ōhot-pixel noiseö. This random pattern of bright pixels is highly correlated among frames. We show how a model of this noise can be employed to greatly reduce i