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Results 166 to 180 of 354
June 16th, 2011, 02:26 AM #166
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Thanks for the incite. Very helpful. After reading yours and another person's comments, I feel that maybe this novel has a more YA feel to it.
The basic themes as I told the other commenter, Window Bar, is "Overall, the themes are exploring the truth of who you are, fighting for something just, friendship and loyalty. I believe that these are important themes for YA's and adults."
As for a sex scene there are none in the novel, however. There is sexual tension between the two main characters. Only a few curse words (damn is used a few times, but is used by a character and represents her speech pattern, language usage, etc. Yet it can be reworded to fit appropriate audience. I also use other dialogue and word usage for that character to establish accent without stereotyping or cliche.) There are a few scenes that deal with death and severe injury. The antagonist to the main characters both minor and major is killed quite gruesomely and another main character is stabbed. All are a part of the development, climax and resolution of the story's problems, etc.
In some ways the journey of the main character is like the main character's journey in "Becoming Naomi Leon." A great YA novel, yet although my story is remotely like "Becoming Naomi Leon," the theme of discovering one's self through the discovery of the truth is apart of both my main character and the one in "BNL".
As I continue to revise and revise, I will look into finding representation that deals with both YA, SFF, and the adult SFF too.
KatG, you're very knowledgeable. Thanks for your input.
Also another question (for anyone). I have many notes on the languages that I have created for the novel, myths/legends etc. I would like to include this in the novel as part of its presentation to agents/publishers.
Good/bad idea? Or something to be used later if published as a companion piece to the novel itself?
Also, the older characters in the book have a similar journey to that of the younger main characters. For example, in the novel itself, the main character finds his aunts manuscript for a short story-like journal that chronicles their own journeys and adventures in the alternate reality. The importance being it serves as a bridge to the past that the main character was too young, or not born, to remember; it explains the origins and connection with Earth and the alternate reality.
I have the notion to include the journal mentioned in the main novel as a separate short short. Again, Good/bad idea to include in the submitted manuscript, or save it as a companion piece for later publishing?Last edited by djjaes; June 16th, 2011 at 02:30 AM. Reason: wording errors
June 16th, 2011, 10:33 AM #167
Save them, because that material is about production costs for whether the publisher wants to include it in the product. Your language notes might be used as an appendix at the back of the novel, but that's something to discuss with the publisher when you have one. The language notes and the short story re the journal are things that you could also use for promotion -- stuff for teens or other readers to explore on your website, etc. You can mention to agents/publishers that you have ancillary material that can be used as enhancement and promotion, but the first thing they are looking at is whether they are interested in the main story usually.
June 16th, 2011, 12:33 PM #168
Young Adult? Yes, it sounds that way to me, too. With any luck, you'll have crossover adult readers anyway.
BTW-- Given KatG's background, her insights will be based on deeper experience than mine.
Make certain you get several outside people (a professional editor, if you can afford one / some erudite friends if you can't) to edit for you. We all make spelling, typing and syntax errors. There is a world of difference between insight and incite, and the word processor's spell check won't be enough. Without a thorough clean-up, no one will read to the end.
Enjoy -- WB
June 16th, 2011, 02:11 PM #169
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October 17th, 2011, 08:26 AM #170
Getting Publishished Part Deux: More questions answered.
I just started reading Tim's post on getting published and thought it was a wonderfully generous thing for him to do. But I also found that his path was much different than my own. And publishing is changing so much right now that I wanted to bring to light some other alternatives. I didn't want to hijack his thread so I thought I might start my own.
Okay...a short background...and I'll try to make it short. I wrote 10 (or 12 can't remember) novels in my "adult years" and tried to get an agent with no success. I finally got "really serious" and studied the market, worked hard to carefully craft the prose, and wrote what I think was the best thing I was capable of (it was literary fiction). I got many agents saying how good it was but that there was no market so I finally threw in the towel. I quit writing and vowed never to write creatively again.
Well as other writers know...as much as you hate writing sometimes you also can't stop the ideas from coming so ten years later I decided to write something "just for me". I had no intention of publishing. I promised I would keep this short so the condensed version is I eventually did decide to publishe and a small press picked it up, had financial problems and then I was more or less "forced" into self-publishing (to meet some deadlines for the 2nd book that fans were waiting on).
I published 5 books (of a six-book series) releasing one every six months and sales slowly grew to about 1,000 a month (across 4 titles) when my 5th book came out it jumped to 2,600 a month and I started thinking maybe I should try New York again. I thought it would take years to get any nibbles but had 7 publishers interested immediately. (I'm sure the fact that at the same time as I was "shopping" the series the books went viral - 10,000 - 12,000 copies a month didn't hurt ;-). But still...for the most part my sales were still very much on the "respectible" end when I was talking to publishers.
So...here we are about a year later and my six-book series is now coming out from Orbit (Fantasy imprint of #2 publisher Hachette Book Group) in just over a month. They fast tracked the project and the books will be released as follows:
- Theft of Swords (Nov 2011)
- Rise of Empire (Dec 2011)
- Heir of Novron (Jan 2012)
I received a much higher advance than most "first time" authors (typically $5,000 - $10,000 a book and I got six figures for three) and have now done it all (self publishing, small press, big-six) so I can talk a bit about the pluses and minues of each. (None of them is the "right" path -- there is only "right for you") ...
So just as Tim did - I'm going to offer up my brain for picking. The lanscape has changed a great deal recently and I think I'm a bit more "plugged into" the "out of the box" approach that is working for quite a few of the authors I'm familiar with.Last edited by sullivan_riyria; October 17th, 2011 at 10:36 AM. Reason: Fixed typo in title
October 17th, 2011, 08:54 AM #171
I just finished reading/sometimes skimmming the whole post...It seems like Tim dropped off and Kat graciously stepped in. She is right on the money about how traditional publishing works.
My intention is to "stay with this post" so hopefully we won't have to drag Kat into it - but as I'm more from "grass roots" and she is more "traditional approach" I'd love to see her comments as we go along.
October 17th, 2011, 10:19 PM #172
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Hello Sullivan,
Which thread are you referring to? And are you opening this thread for us wannabes to ask questions?
October 18th, 2011, 12:35 AM #173
We merged you. We stickied the thread to be a general topic of interest to writers, so they could ask publishing questions.
For me, having worked with self-publishing authors long before the e-book market took off, the recent distinction of the indie field as grass roots and publishing as "traditional" publishing is not really there, I guess, but that doesn't mean that authors aren't facing different factors coming into the market from different directions. You are pretty much running the whole gauntlet, Sullivan, so I'm sure people will find it very helpful.
One thing to keep in mind re Sullivan's interaction with publishers for reprint: 10,000 copies sold in total, much less 10,000 a month, from a self-published author is not considered "respectable" or medium sales for publishers. It's considered extremely successful and reflecting the potential for really large audiences in a published edition. The sales levels they are looking at for authors on their lists and self-published authors are not the same. Just thought I'd throw that distinction in there as we have writers doing every kind of publishing here at this point. (Basically, I'm saying that Sullivan is being too modest here.)Last edited by KatG; October 18th, 2011 at 12:42 AM.
October 18th, 2011, 10:06 AM #174
October 18th, 2011, 12:22 PM #175
Congratulations on your success, Sullivan. From where I'm sitting as a newbie author who only just started querying for his first book, your story makes it sound like I am standing at the bottom of a mountain range looking up your trail, Many miles above. What advice can you offer a newbie author like myself that has no literary credentials? (to make the hike up the mountain less difficult)
Second question. When you were writing a manuscript who was your most helpful person for you to turn to when you had a question about the direction of your plot, or just editing in general, and why?
Thanks for your time, Sir. -IK
October 18th, 2011, 10:09 PM #176
This thread - I guess I had a seperate thread because my path was different then Tim the OP. But yes, I'm hear to answer any questions about getting published (self, small press, or big-six) and what's going on in the industry...as least as I see it.
There are many people who may have different opinions which is great. All I can speak to is what I've experience first hand as I've done all three and I see that the business is a lot different than when I started in this a decade or so ago.
October 18th, 2011, 10:15 PM #177
Many people point out, and correctly so, that self-publishing has alwasy been around. The difference today is that for the first time we now have distribution channels (especially fore ebooks). And as ebooks gain more and more ground it means that authors really can make a decent living with self-publishign wherein the past most could not.
Well I can't speak to what the big-publishers consider a "good track record" as I have no experience being on that side of the fence. What I do have is some knowledge of what some other self-published authors have sold. I personally know people who have sold 300,000 books in a few months. And of course there are the Locke's and Hockings who sell 1,000,000 copies but I consider them Outliers like King and Rowlings. I guess my point is that in the circle I run in (the authors I know that self publish) my numbers were not nearly what theirs were/are.
October 18th, 2011, 10:20 PM #178
My wife runs the small press that I was with before Orbit picked me up and although on some months I was the "top seller" there were others when I was eclipsed. Examples:
- Nathan Lowell - 3,600 copies of Full Share in the first week of release and 9,500 in a single month with half the titles as I had
- Marshall Thomas: 19,500 copies in a single month (across six-titles)
- Leslie Ann Moore: 5,000 copies across 2 titles in a month
Then there are authors I know like H.P. Mallory who was selling 20,000 books a month when I was selling 10,000 and David Dalglish routinely sells about 11,000 a month
I venture to say most people have never heard of any of these names because in many respects we are all "small frys" but the ebook revolution has been very good to us and we could have never sold at these numbers pre Nov 2010.
October 18th, 2011, 10:47 PM #179
Well the first thing is to realize that EVERY author in existence was where you are now. i.e. a newbie with a mountain to climb. Persistence is the absolute key. The only sure way to fail is to quit. But it can be difficult at times and you'll want to throw in the towel - heck I did for a decade. I think the biggest mistake new authors make is they can't wrap their heads around the "business side". You have to "think like a publisher" whether you are published through someone else or yourself. Major keys... (assuming fiction) is that genre is easier than more broad based work like literary fiction. And multiple books (i.e. a series) is really necessary to make "good money". I think most would be very hard pressed to do well with a single book. Frequent release dates (6 months or less) keep your name in front of your fans. Book bloggers are amazing people who work tirelessly to get the word out for authors - treat them with the utmost respect, and help them do their job...and always thank them as they are (IMO) the most important ingredient.
Until you asked this question I didn't realize that I don't ever ask anyone about direction in plot etc while I'm writing. My process goes like this.
- I outline - but very briefly and I'll deviate from it as the story develops if needs be.
- Once I finish I take a few day to think is there any way that I can raise it another peg. In many ways I'm running the whole story through my head looking for how I can produce a bigger bang. This usually results in some fairly major changes
- Once I have it the way I'm happy it goes to my wife. She is hands-down the best "story editor" I have ever seen. She finds plot holes...tells me what areas need expanding...which are dragging...if I started in the wrong place...missed opportunities where a slight change will take it to that next level that I didn't see. In most cases she may see a problem and present a solution...more often than not I don't use the solution but it will lead me to an "even better idea.
- After we've got it the way we want it. I send it to beta readers and writer friends whose opinions I trust. This may lead to some more changes but they are relatively minor and usually just a tweak here and there - I don't think I've ever made a large scale change based on that feedback.
Keep in mind this is what I do...and every author has a different approach it may not work for you, but you asked so I thought I should answer.
October 18th, 2011, 11:09 PM #180
thank you. Thats what i wanted to know. I dont have the editor/wife. Nor many friends that read SF/F, or even read fiction Makes it difficult at times. I do appreciate your reply tho.


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This is a high quality replica of Hans Wegner's famous "Wishbone" chair (aka the Wegner Y chair or the Wegner CH24). I am the proud owner of an original that I got from my grandfather's estate, and I got this one so I could have a set (but without having to pay the enormous price of an original). Wegner is a world-famous mid-century Danish designer who passed away a few years ago (and ever since the market for his work has gone through the ceiling). For fans of classic mid-century design, this piece is well worth the price.
We have owned the real Wegner chairs for several years. And we wanted a couple of more chairs for extra guests but did not want to spend the money that we did on the originals. After reading the reviews, we took a chance and ordered two. We were indeed surprised by the quality. The finish on the wood and twine on the seats are very similar and the feel when sitting is no different than the real Wegners. And it only cost us on a fraction of what we spent on the real thing. Love them!!A
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Rustic cabin built in the 60s in quaint Mayfield Village. Mayfield Village is about 15 minutes east of I-5 on Highway 12 (Exit 68) in Lewis County, Washington--90 minutes from either Portland or Seattle, 2 hours from Yakima. The village has a marina and resort on Mayfield Lake, which is a 13-mile-long lake with excellent fishing and water sports as well as beautiful wooded shores and shallow areas that can only be reached by boat for wading and sunbathing. Our efficient cabin has a full kitchen, 1 bedroom, 1 bath; central room divides into 2 separate sleeping areas with futons, so can accommodate 6. Large covered deck off back of cabin, small private deck off bedroom. Minutes' walk to marina. Use of our membership to marina included in rental. Bring your boat and use the slip, play at the beach, attend the Saturday Night Dance (during the summer). Fishing, waterskiing, kayaking are popular on this large lake. Marina has canoes and kayaks, a pontoon boat for rent, as well as a store and restaurant with wine and beer.
Above the friendly little village are miles of trails in state forest for hiking and ATVs.
For year-round recreation, Mt. Ranier, Gifford Pinchot National Forest and Mt. St. Helens are within 1 hour's drive for beautiful hiking, camping, cross-country skiing and exploring.
White Pass ski resort (pictured below) is a 90-minute easy drive for family-friendly skiing during a winter vacation.
Our cabin is not fancy, does not have a lake view, but it is very functional and full of great family memories. We hope you can make some of your own here.
Our trip at your place was really fun. The cabin was really enjoyable and we felt at home immediately. We went canoeing both days and caught some trout. I even managed to tip the canoe over out in the middle of the lake...what a fridgid experience that was! Anyways...we barbequed and relaxed and had fun and did see the waterfall.
Thank You for the experience and we will recommed that other people choose your cabin and friendliness when they heading that direction.
Any time of the year, Lewis County has beautiful mountains and rivers to explore. Mt. Ranier National Forest, Mt. St Helens and Gifford Pinchot National Forests all have miles and miles of trails with alpine lakes and breathtaking scenery. Because Mayfield Lake is so close to both Portland and Seattle, it is easy to really get "away" from the city quickly--an hour-and-a-half drive
Summer: Boating, fishing, swimming, waterskiing, hiking, ATV trails, birdwatching (including eagles and osprey at the lake)
The lake is a 5-minute easy walk from cabin with swimming, nice protected boat docks, restaurant, store, and the family-friendly Saturday Night Dance in the summers
Winter: Downhill and cross-country skiing--White Pass (pictured below) is an easy 90-minute drive away, Mt. Ranier, Giffford Pinchot National Forest and Mt. St. Helens within 1 hour's drive
Centralia is about 1/2 hour away with antique and outlet stores, McMenamin's Pub with movies and burgers, Amtrak station
Casinos are also within driving distance


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Back to Newsletters
July 2009 HCV Advocate
Download English printable version
In This Issue:
Pregnancy Drug Categories Alan Franciscus, Editor-in-Chief
HealthWise: Hepatitis C and Metabolic Syndrome Lucinda Porter, RN
FDA Takes Action on Acetaminophen Liz Highleyman
Book Review - Healing Hepatitis Lucinda Porter, RN
Consequences of Hepatitis C - Cost of a Baby boomer Epidemic of Liver Disease Alan Franciscus, Editor-in-Chief
HCV Advocate Eblast Stay informed on the latest news ..click here to register for email alerts
Back to top Pregnancy Drug Categories Alan Franciscus, Editor-in-Chief
Which drugs are safe to take while a woman is pregnant? If a woman becomes pregnant while on therapy is there a risk to the fetus? If a woman is pregnant, which drugs increase the risk of birth defects? To help guide medical providers and patients, the Food and Drug Administration (FDA) has established certain categories that for the most part define what is safe and what is not safe. But there are gray areas within most of the categories. This is why it is so important to seek medical advice—medical providers base decisions on a variety of factors, such as does the risk outweigh the benefit, personal experience using a certain drug and the latest medical research.
The categories are only applied to medications that have been approved by the FDA. Over-the-counter medications (OTC), herbs and most supplements are not assigned a pregnancy classification unless they have been previously scrutinized by the FDA. In these instances medical providers will use their previous experience or information from scientific sources to advise what is safe or unsafe to take.
In a perfect world every drug would have solid scientific data on humans to advise about the potential risk of medications, but this isn't always the case in the real world. There are many reasons why studying a drug in humans isn't feasible or why pharmaceutical companies don't pursue these trials, such as the obvious risk of exposing certain drugs to pregnant women, the cost of studying the issues and the potential lawsuits the pharmaceutical companies may be exposed to. As a result much of the information about medications and pregnancy is based on test tube or animal studies and anecdotal information about drugs that have a long history of use.
"If a woman is pregnant or thinking about becoming pregnant she should talk with her doctor about any prescribed medications, over-the-counter medications, herbs, and/or supplements that she is taking or thinking of taking."
Pregnancy Categories:*
Category A: In human studies, pregnant women used the medicine and their babies did not have any problems related to using the medicine.
Category B: In humans, there are no good studies. But in animal studies, pregnant animals received the medicine, and the babies did not show any problems related to the medicine.
In animal studies, pregnant animals received the medicine, and some babies had problems. But in human studies, pregnant women used the medicine and their babies did not have any problems related to using the medicine.
Category C: In humans, there are no good studies. In animals, pregnant animals treated with the medicine had some babies with problems. However, sometimes the medicine may help the human mothers and babies more than it might harm them.
No animal studies have been done, and there are no good studies in pregnant women.
Category D: Studies in humans and other reports show that when pregnant women use the medicine, some babies are born with problems related to the medicine. However, in some serious situations, the medicine may still help the mother and the baby more than it might harm them.
Category X: Studies or reports in humans or animals show that mothers using the medicine during pregnancy may have babies with problems related to the medicine. There are no situations where the medicine can help the mother or baby enough to make the risk of problems worth it. These medicines should never be used by pregnant women. *Source: Food and Drug Administration
FDA Approved Medications for Treating HBV and HCV.
Ribavirin warning: Ribavirin has been shown to cause birth defects and miscarriages. Women of childbearing age, their male partners, and female partners of male patients taking ribavirin must use at least two forms of effective contraception during treatment and during the six-month post-treatment follow-up period. Back to top Healthwise: Hepatitis C and Metabolic Syndrome —Lucinda Porter, RN
"Hepatitis C Patients with Metabolic Syndrome Are at Greater Risk of Death," wrote Liz Highleyman, reporting on research presented at the 2009 European Association for the Study of the Liver meeting. This research is a wake-up call for those with chronic hepatitis C virus infection (HCV). This month, we'll discuss metabolic syndrome—how to avoid it or manage it if you already have it.
Experts don't agree on the definition or even if metabolic syndrome is an actual disease. Generally recognized is that there are a collection of signs, warning of potential problems, such as heart disease, stroke, and diabetes. Those with HCV and metabolic syndrome are at risk for early death.
The National Heart Lung and Blood Institute developed the following guidelines to identify who is at risk for metabolic syndrome. The more of these a person has the greater the risk for serious medical complications. These signs include:
Some people have uncontrollable risk factors for metabolic syndrome. These include:
There does seem to be a link between HCV and metabolic syndrome, but research has yet to state unequivocally that HCV is a risk factor. What is known is that having the two is a risk factor for early death.
Here is the good news – the warning signs for metabolic syndrome can be managed, reduced and often eliminated by lifestyle changes. Yes, lifestyle changes. Did I hear someone groan? Yet another reason to manage our weight and stay physically active!
Those of you who are still reading this article, congratulations. Perhaps you are like me – not thrilled about reducing calories and exercising more – but even less thrilled about the alternative. Let's talk about the alternative. If it was just premature death, then there wouldn't be much to discuss. Some of us cry, "I'd rather die than spend the rest of my life on a treadmill and eating celery." However, it doesn't work that way. Typically people who are unhealthy spend the last third of life in decay and discomfort.
Simply put, it isn't like one day we are out frolicking around, eating fried chicken and a pint of Ben and Jerry's Cherry Garcia and suddenly we keel over in bliss. Rather, it takes decades – we slow down, we ache, take medication, do less, enjoy less, go to the hospital and doctor a lot, get tubes inserted in places where we don't want tubes, maybe have a stroke and can't walk or talk, and on and on this goes. By the way, Ben Cohen of Ben and Jerry's had a coronary bypass following a heart attack in 2001.
Or, we can get some help and change our lives – for the better. Easy? Of course not. I understand. I am writing this during one of the worst brain fog episodes I have had in years. I'd rather sleep than exercise, but physical fitness is non-negotiable for me. I do something every day – rain or shine. It's the law. Worth it? Absolutely.
There are tricks to making lifestyle changes. The first trick is to find out what works for you. Look at where you have been successful in the past. What worked and what didn't? What motivates you? Do you work better alone, with a partner or in a group? Do rewards help?
If you are at risk for metabolic syndrome, aim for the following:
If you are overweight and have had trouble losing those pounds, consider using the one tool that has consistently shown to help with weight loss – a journal. To gain control of what we eat, there is nothing like looking at it in black and white. You can do this online or on paper, but either way, you need a tracking system. Calorie counting is a good one, particularly with the Internet. Some links are provided at the end of this article.
If you keep a journal, set 3 to 5 goals. Make them reasonable, specific and achievable. A goal of "getting healthy" is too general. More specific is "lose 12 pounds in 6 months" and "walk 30 minutes daily at least 5 times a week." Write 3 reasons why you have these goals. Examples are "to lower blood pressure, to feel better, and to not have to buy a new belt."
Look at these reasons and goals every day. Use them to remind you why health matters. If you fall off the wagon, don't beat yourself up. That just leads to more problems. Also, don't quit, but recommit. If we all quit every time we had a setback, we'd never get anywhere.
Declining health is a drag. It is a hard time to make changes, but start slow, take baby steps and be patient. Although it takes time, time passes either way. Doesn't it make sense to watch time pass while we are taking a walk rather than playing solitaire? Besides, what do we have to lose, besides our waistlines and misery?
Further Information
Back to top FDA Takes Action on Acetaminophen —Liz Highleyman
The pain reliever acetaminophen is generally safe for most people when used as directed, but it can cause life-threatening liver injury if taken at high doses or by individuals at risk for hepatotoxicity.
As acetaminophen toxicity remains one of the leading causes of acute liver failure in the United States—accounting for an estimated 50,000 emergency room visits and 500 deaths annually, according to the American Association for the Study of the Liver—the Food and Drug Administration (FDA) has mandated stronger warnings and stricter regulation of the drug.
Acetaminophen Liver Toxicity Acetaminophen, like many drugs, is metabolized by the liver. If the normal processing pathway is overwhelmed by a high dose, a different pathway known as the cytochrome P450 system takes over. This leads to production of a metabolite, NAPQI, that is toxic to liver cells.
If acetaminophen toxicity is diagnosed in its early stages—which can be difficult due to nonspecific symptoms and sometimes slow onset—N-acetylcysteine (NAC) can be administered as an antidote; NAC restores the natural antioxidant glutathione, which detoxifies NAPQI. But as liver damage progresses, decompensation may occur, necessitating a liver transplant in the most severe cases.
A significant proportion of acetaminophen-related liver toxicity is due to intentional overdose, typically a suicide attempt. Most cases of serious liver damage occur in people who have taken at least 10-15 grams—much more than twice the recommended total daily adult dose of 4 grams (4,000 mg).
However, accidental overdoses are also common, accounting for about half of all cases, in part because the drug is present in so many products. In addition to the familiar Tylenol brand, acetaminophen—also known as APAP or paracetamol—is an ingredient in hundreds of prescription painkillers (often combined with narcotics such as hydrocodone or oxycodone) and over-the-counter or OTC products (including many cold, cough, and sinus remedies) (see sidebar for a partial list). This ubiquity increases the likelihood that people will unknowingly mix acetaminophen-containing products, thereby exceeding the maximum recommended dose.
Drinking even a small amount of alcohol while taking acetaminophen—or a few hours before or after doing so—increases the risk of liver toxicity. Research indicates that people with pre-existing liver disease, including chronic viral hepatitis, have an elevated risk of acetaminophen-related hepatotoxicity, although most hepatitis B or C patients with compensated liver disease can safely use the drug at recommended doses. Finally, some individuals are prone to acetaminophen toxicity at or near the recommended amount for unknown reasons, possibly having to do with genetic factors.
Revised Labeling On April 28, the FDA issued a final rule requiring manufacturers of OTC pain relievers and fever reducers to revise product labeling to include warnings about potential safety risks, including liver damage associated with acetaminophen and gastrointestinal bleeding due to nonsteroidal anti-inflammatory drugs (NSAIDs), which include aspirin and ibuprofen.
"Acetaminophen and NSAIDs are commonly used drugs for both children and adults because they are effective in reducing fevers and relieving minor aches and pain, such as headaches and muscle aches," Charles Ganley, MD, director of FDA's Office of Nonprescription Drugs, stated in an agency press release. "However, the risks associated with their use need to be clearly identified on the label so that consumers taking these drugs are fully aware of the potential harm they can cause. It is important that they know how to take these medications safely to reduce their risk."
Under the new rules, manufacturers must prominently list all active ingredients in a product both on the external packaging and on the bottle. The label must warn of the risk of severe liver damage with acetaminophen and stomach bleeding with NSAIDs. These changes must be made by April 29, 2010.
The full revised rules, formally titled "Organ-Specific Warnings; Internal Analgesic, Antipyretic, and Antirheumatic Drug Products for Over-the-Counter Human Use"—consisting of 25 pages in the Federal Register—are available online at http://edocket.access.gpo.gov/2009/pdf/E9-9684.pdf.
What Took So Long Many clinicians and consumer advocates consider the new warning long overdue. FDA advisory panels have recommended a liver toxicity warning for acetaminophen on several occasions (in 1977, 1988, 1993, and most recently 2002) but this was never formally adopted—an outcome some advocates attribute to pharmaceutical industry lobbying. However, in 1998 the agency did require a label warning stating, "If you consume three or more alcoholic drinks every day, ask your doctor whether you should take acetaminophen or other pain relievers/fever reducers."
In 2004, the FDA launched a public education campaign about the risks of acetaminophen, but the effort was small and poorly funded. That same year, the agency asked state pharmacy boards to consider requiring stronger labeling on prescription acetaminophen products, but by 2008, none had done so. Some companies voluntarily strengthened their side effects warnings, but not enough to satisfy FDA officials.
In December 2006, the FDA issued proposed labeling requirements for OTC acetaminophen products, and in 2007 the agency's Center for Drug Evaluation and Research convened a multidisciplinary working group to discuss the issues of acetaminophen-related liver injury and possible prevention measures. This group devised a report with options to be presented for public discussion and comment, which provides the basis for the agency's latest actions.
Further Steps On June 29 and 30, after the HCV Advocate went to press, the FDA held a joint meeting of the Drug Safety and Risk Management Advisory Committee, the Anesthetic and Life Support Drugs Advisory Committee, and the Nonprescription Drugs Advisory Committee to discuss the public health problem of liver injury related to acetaminophen in OTC and prescription products and to consider further steps the agency might take to reduce the risk.
"The association between acetaminophen and liver injury is not common knowledge. Consumers are not sufficiently aware that acetaminophen can cause serious liver injury, and their perceptions may be influenced by the marketing of the products," the FDA wrote in its meeting announcement. "Current labeling on OTC products may be overlooked, as can the patient information provided with dispensed prescriptions. Programs to educate the public about safe use of acetaminophen have been small and encountered a number of obstacles. Advertisements of OTC drugs often emphasize the effectiveness of products, but are not subject to the same requirements to offset such messages by providing warning information as prescription products. Also, acetaminophen is available in retail outlets in large quantities (e.g., 500 tablets per bottle) which may contribute to the perception that the ingredient is unlikely to be harmful."
Possible measures include lowering the recommended single dose and cumulative daily dose, reducing the amount of acetaminophen in maximum strength tablets and liquid pediatric formulations, removing acetaminophen from combination products, and restricting the number of pills that can be sold at one time. Such a restriction might help reduce intentional overdoses, but likely would not reduce the risk for people who develop liver toxicity at or near the recommended dose. The U.K. instituted acetaminophen pack-size restrictions in 1998, but whether this has decreased deaths due to toxicity remains subject to debate.
Outcomes of the FDA committee meeting will be covered in future issues and on the HCV Advocate web site (www.hcvadvocate.org).
Common Products Containing Acetaminophen (Not a complete list)
Prescription Darvocet Esgic Hydrocet Lortab Percocet Roxicet Vicodin Zebutal
OTC Actifed* Alka-Seltzer Plus Anacin* Comtrex Contac* Dimetapp* Dristan Excedrin Midol* Nyquil Panadol Robitussin* Sinutab* Sudafed* TheraFlu Tylenol
*Certain products under this brand name. Back to top Book Review: Healing Hepatitis Lucinda Porter, RN
Book Review – Healing Hepatitis C: A Patient and a Doctor on the Epidemic's Front Lines Tell You How to Recognize When You Are at Risk, Understand Hepatitis C Tests, Talk to Your Doctor About Hepatitis C, and Advocate for Yourself and Others, by Christopher Kennedy Lawford and Diana Sylvestre, Harper Paperbacks, 2009, paperback, 208 pages, $14.99
There are a number of good books about hepatitis C (HCV). I have read most of them. When I ordered Healing Hepatitis C, I expected it to be much like the others. What I didn't expect is that I would pick it up and not want to put it down until I finished it. Yes, it was that good.
I am acquainted with one of the authors, Diana Sylvestre. A physician, researcher, and faculty member at the University of California, San Francisco, Sylvestre's passion is working with disenfranchised patients. Her warmth shines through the pages. The other author, Christopher Kennedy Lawford (yes, of the Kennedy-Lawford family) provides good humored insight from the patient's perspective. His story is inspirational and honest.
Healing Hepatitis C is different from most of theother HCV books. The format is a dialog between the two authors, but it manages to come across as if the authors are speaking to the reader. Although I enjoyed it immensely, this style may not appeal to everyone. My only criticism of the book is sometimes I wasn't sure which author was narrating.
Lawford expands the dialog concept when he converses between "Sober Chris" and "Junkie Chris." I don't know how other readers will find this, but it worked for me. It illustrates some of the turmoil that we experience over this disease, particularly regarding treatment. I assume that patients who have not wrestled with addiction will still be able to relate to the inner struggles that seem to go with living with HCV.
Lawford and Sylvestre address the core issues and fears associated with HCV treatment that many of us have. This is the magic of this book. It is real yet it reads like a novel. The book is not highly technical yet it succeeds in getting across a lot of information without boring the reader. The Online Resource section provides tools for the reader wanting to know more about various aspects of HCV.
Healing Hepatitis C offers genuine hope for HCV patients. It can be summarized best in the authors' own words, "…we hope to walk you through the process of facing the diagnosis and treatment head-on, to show you that it is possible to get through this hepatitis C thing—and to be cured—without surrendering your life to it." That sounds like inspiration to me.
Review by Lucinda K. Porter, RN
Back to top
New Patient Education Module Click here
Check out all of our modules at www.hcvadvocate.org/hepatitis /training_resources.asp
Back to top Consequences of Hepatitis C: Cost of a Baby Boomer Epidemic of Liver Disease —Alan Franciscus, Editor-in-Chief
In May 2009 a report commissioned by Vertex Pharmaceuticals, and compiled by Milliman on the future disease burden of hepatitis C (HCV) was released. The report estimated the future cost of hepatitis C over a 20-year period.
The authors noted a couple of caveats or limitations of the study: First, the analysis did not factor in development and use of more effective medications to treat hepatitis C, such as the new HCV protease and polymerase inhibitors that could dramatically reduce both future deaths as well as the financial impact of HCV disease progression; secondly, the authors also noted that the report is based on the NHANES study that grossly underestimated the prevalence of HCV in the United States.
Key points of the report:
The authors concluded, "In the absence of improved and accessible treatments that can alter the progression of disease, payers, especially Medicare, will feel the impact of a baby boomers' advanced liver disease epidemic.
In addition to the new and more effective treatments that offer hope of reducing the HCV disease burden is the introduction of new HCV antibody test – the Orasure HCV Rapid Oral Antibody test. The new test will be easier to use for mass screenings and will help to identify some of the 78% of people who have hepatitis C and don't know it. Integrating the newly diagnosed as early as possible into medical services to manage and treat hepatitis C is the best possible strategy for reducing the future HCV disease burden. But the real tipping point will only come if there are massive amounts of dollars pumped into HCV research to provide expanded testing, management and treatment. One can only hope!
The entire report can be viewed on the Vertex Pharmaceuticals Web site: http://www.vrtx.com/millimanreport.html Back to top Back to Newsletters
About Hepatitis | News Updates | Community & Support | Resource Library | About HCSP | Contact Us | Site Map | Recursos en Español | Home
© 2009 Hepatitis C Support Project


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World record planned to mark Thiruvalluvar Day today
S.V.G.V. Matriculation School in Karamadai is gearing up for a world record event, wherein the largest portrait of Thiruvalluvar will be created using pots on January 16 to mark Thiruvalluvar Day.
A release from the school said that as many as 1,330 students representing the 1,330 couplets in Thirukkural will stack the pots together to make the portrait.
The pot portrait has been planned to reach a height of 133 feet using 4,000 pots and each student would write a Thirukkural on three pots.
Elite World Records, Asian Records Academy in Singapore, India Records Academy in Mumbai and Tamil Book of Records in Chennai are the world record adjudicators will be present at the venue on January 16, according to the press release.
Keywords: Thiruvalluvar Day, S.V.G.V. Matriculation School


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Scottsdale Healthcare's three hospital gift shops are easily accessible and well-stocked stopovers for patients, families and visitors looking for a wide selection of interesting merchandise. Conveniently situated in the lobbies of the Osborn Medical Center, the Shea Medical Center and the Thompson Peak Hospital, the shops are managed by a dedicated staff of smiling volunteers. Members of this distinctive "sales force" donate their time to make the sites welcoming and convenient for all who visit.
Each shop has its own special personality, but all three have ample stocks of personal care items such as toothpaste and brushes, shampoo and shaving gear. "Special" items such as candy, greeting cards, games, snacks, stamps, stuffed animals, balloons, jewelry, and figurines are available for the shopper seeking something special for friends and loved ones.
Looking for something special but you're not close to one of our hospitals? Just call one of our shops and we'll gladly assist by phone. Or, if you're visiting a patient, please stop in and browse for a special gift to cheer up that person. Our talented staff will be happy to assist. (See below for telephone numbers and hours of operation)
(Shop located at east end of main floor near Outpatient Entrance) 7400 E. Osborn Rd. Scottsdale, AZ 85251 480-882-4055
Hours of Operation:
(Shop located in main lobby to left of Information Desk at south entrance) 9003 E. Shea Blvd. Scottsdale, AZ 85260 480-323-3055
(Shop is located inside main entrance, to the left) 7400 E. Thompson Peak Pkwy. Scottsdale, AZ 85255 480-324-7052
Each retail location offers membership/ loyalty programs for discounts on your shopping experience.


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May 4, 2011 By Steven Sandberg MEDFORD, Ore. — Seeing the effects of March's earthquake and tsunami in Japan has homeowners in the Rogue Valley wanting to be sure they have a solid footing in the event of an earthquake. Emergency managers it takes more than just being ready to ride out an earthquake. Plans … Continue reading »
Earthquake: Ready To Ride It Out? Part 2
May 3, 2011 By Steven Sandberg WHITE CITY, Ore. — Japan's devastating earthquake in March was also able to cause damage across the Pacific Ocean at the Oregon and California coasts. It has researchers looking into what kind of damage a similar quake would cause in Southern Oregon. Geologists say the Rogue Valley is in … Continue reading »
Earthquake: Ready To Ride It Out? Part 1
May 2, 2011 By Steven Sandberg BROOKINGS, Ore. — Emergency responders on the Southern Oregon and Northern California coasts admit they were not fully prepared when March's earthquake in Japan triggered a tsunami along the West Coast. Now, after millions of dollars in damage, crews say things need to change if we are to be … Continue reading »


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A Field Guide To The War On Wind Power (Part Two)
By Mike SeccombeOctober 5, 2012
People living near wind farms have complained of symptoms ranging from excessive scratching to loss of muscle tone. But do wind turbines really pose a credible health risk?
Question: When is a disease not a disease?
Answer: When it's a syndrome.
The word syndrome is usually applied to a bunch of symptoms indicative of a disorder or disease. In the case of wind-turbine syndrome, however, it is just a bunch of symptoms — a bewilderingly vague and all-inclusive array of alleged symptoms.
To those who say it's real, wind-turbine syndrome is indicative of the effects of low-frequency sound, so low it can barely be heard, and 'infrasound' which is so low it cannot be heard at all.
To those who don't believe it's real, wind-turbine syndrome is indicative of either hysteria or NIMBY-ism.
And this dispute takes us back to where we began yesterday's story, to the verbal stoush between Dr Michael Wooldridge, former Liberal federal health minister, and Dr Simon Chapman, Professor of Public Health at Sydney University.
Dr Wooldridge, you see, is a director of the Waubra Foundation, an organisation which exists to publicise the alleged health risks posed by wind turbines. The Waubra Foundation is the "go-to" body for other organisations hostile to wind power, such as the Australian Environment Foundation — the astroturfing, climate-change-denialist organisation we've already examined — and the Landscape Guardians, about which we'll say more shortly.
And Chapman has taken it upon himself to point out, often, vigorously, and sometimes mockingly, that the anti-wind health campaign lacks credible scientific evidence to back it. The professor also doesn't hold back in his assessment of Wooldridge and the others who run the Waubra Foundation and Landscape Guardians.
They are "landed gentry", he says, who are cynically fostering "panic" about a non-existent health threat.
"A lot of these people are arch-conservatives who don't subscribe to global warming and think it's a lot of green nonsense," he says. "They just don't want them [wind turbines] because they think it destroys their amenity," he says.
Chapman keeps a tally of the claimed dire consequences of wind-turbine noise. As of September 14, he had documented 198 such claims, ranging from brain tumours to heart disease to loss of balance, to the enigmatic condition "loss of bowels" to relationship breakdowns among peacocks. The list makes for entertaining reading.
Chapman says he got involved in the issue because, as a sociologist, he was interested in the history of medical panics.
"These things go back well into the 19th century," he says, pointing out that in 1888 the British Medical Journal warned of a plethora of diseases attributable to the use of the telephone.
"In this century [there have been similar panics about] TV, electric blankets, microwave ovens…the most recent one of course being mobile telephone towers," he says.
This wave of hysteria about wind turbines, he says, is being deliberately encouraged by people who have vested interests in stopping alternative energy, who are pursuing political advantage or who are simply looking for cover for their NIMBY-ism.
Chapman has studied the scientific evidence: "17 reviews, collections of what has been published, and all of them have basically said there is no evidence that infrasound is harmful to humans," he says.
To mention just a couple of the studies: in 2010 the National Health and Medical Research Council found no direct health effects from wind farms that could not be mitigated by existing planning requirements.
And the head of medicine at the University of Adelaide, Professor Gary Wittert, carried out a study of the medical prescriptions issued to people living close to wind farms, compared with others living further away, and found no difference in the medications taken.
Says Chapman: "This is very, very obviously a psychogenic phenomenon."
And it's only surfaced in recent times, although wind-generated power has been around for many years. Chapman points out that in some areas, such as Esperance in Western Australia, turbines have long operated without any associated health problems having been reported. Millions of people in Europe have lived with turbines for decades and are untroubled by illnesses that might be attributed to wind farming.
But once you convince people that something poses a threat to their health, they are apt to look for symptoms of illness in themselves and, if they find any symptoms, to attribute them to that thing.
Chapman says the most commonly reported symptoms of wind-turbine syndrome are "sleep problems and high blood pressure".
To which he adds, "about one-third of the population have sleep problems. High blood pressure afflicts 20 per cent of the population".
Chapman concedes wind farms may contribute to these kinds of ill health, but not directly.
"If you just don't like them [wind farms], when you see them going up and you feel powerless to stop them, you say 'this really makes my blood boil' — and it kind of does.
"That annoyance can turn into somatic problems — you can worry yourself sick. So if you're angry or depressed or worried, you can become ill.
"These reviews show the best predictor of annoyance is not anything like proximity to turbines or any measure of noise emanating from them. The biggest predictor of annoyance is pre-existing attitudes which are negative towards wind farms."
Chapman also doesn't discount the possibility that some people living close to commercial wind farms are motivated by the hope that the wind power developers will buy them out to shut them up.
Dr Michael Wooldridge, for his part, is surprisingly mild in what he has to say about the health impacts of wind turbines.
"I have no doubt that infrasound exists," he says, in what amounts to a statement of the obvious. No-one denies it exists; the argument is over whether it could cause health problems.
"I have no doubt it's a nuisance and should be treated as any other environmental nuisance," he says.
"I don't for a moment sign on to every silly thing anyone's ever said around the world. But I think it can, in some people, have a very substantial effect.
"There is, absolutely, growing evidence, in peer-reviewed articles, that infrasound is deleterious to human health."
Wooldridge provided The Global Mail with web links to various scientific journal articles. Almost all were from the one publication, the Bulletin of Science, Technology and Society. There was, however, one from the British Medical Journal, of which more later.
What really animates Wooldridge is his personal situation, his 120-hectare rural property which now has wind farms abutting two boundaries.
He remembers "standing for hours on the back of a D8 bulldozer while my grandfather cleared the land, 50 years ago," he says.
Then the "appallingly arrogant power companies" moved in next door; and now "I've been prevented from enjoying what is my special spot on the planet".
He also has "a philosophical problem" with government providing subsidies to energy companies in order to set up wind farms.
But what got him involved with Waubra was a personal relationship with the organisation's chairman, Peter Mitchell.
"He was president of the national Stroke Foundation when I was health minister," says Wooldridge.
You will remember Mitchell from Part One of this article. He's the bloke with the mining background, the advocate of nuclear power and speaker at that AEF conference. Simon Chapman identifies him as the central figure in both the Landscape Guardians and Waubra Foundation.
Environmentalists tend to play up Mitchell's background in the energy sector as his motivation for opposing wind power. But one of his better-informed opponents, Simon Holmes a Court — a wind advocate who helped set up, and remains chairman of, a small community-owned wind farm at Daylesford, Victoria — does not believe that. He thinks that what drives Mitchell is "wanting to keep turbines away from his family property".
Mitchell's family owns Mawallok, a heritage-listed property, west of Ballarat, a few kilometres from a proposed wind farm.
When contacted by The Global Mail, Mitchell is at first reluctant to speak. He doesn't want to talk to us if we have views like the ABC, or Fairfax media, he says.
He protests that the Landscape Guardians is a "terribly informal, grassroots group", set up long before wind farms were an issue, by members of the National Trust who were unhappy about developments that "defaced" the countryside.
In contrast, the Waubra Foundation is a group consisting just of its half-dozen office holders, which, Mitchell insists, is not "linked" to the Landscape Guardians.
"'Link' is a word which implies that we're all trying to do something which is probably against the public interest," he complains.
Sure, he says, Foundation office holders attended meetings convened by various Guardians groups, however Mitchell says this is not a "link", but a "service" provided to warn people about the effects of turbines.
"It [the Waubra Foundation] is just a small group of people that encourages other people who ring up and say 'Can you help us?'"
When asked about connections between Waubra and the AEF, he acknowledges his role as a speaker and says he also advises the AEF about health questions.
"We are the go-to people for health," he says.
In fact, Mitchell was involved in the establishment of both the Guardians and the Waubra Foundation. In 2011 Crikey reported that "The Waubra Foundation, the Landscape Guardians and Mitchell's investment company Lowell Capital all have the same post office box."
Perhaps more significantly, Waubra office holders have also been prominent in numerous Landscape Guardians groups, as has been variously recorded, notably by the early investigations of Sandi Keane, and by Labor MP John Murphy in Parliament in February this year.
Speaking with The Global Mail, Mitchell refuses to say whether or not he believes climate change is human-induced. Randall Bell, however, president of the Victorian Landscape Guardians, friend of Premier Ted Baillieu and, like Mitchell, ex-National Trust, when not writing anti-wind opinion pieces for Murdoch-owned newspapers, is a climate-change denier.
After our conversation, Mitchell also sent email links, including the British Medical Journal article Wooldridge pointed us to. And, in fairness, it should be recorded that the BMJ piece referred to several studies in which people living up to 2 km from turbines reported having experienced worse sleep since living near the turbines. Its conclusion, in essence, was that wind-turbine noise, like that of trucks, trains and aircraft, could cause sleep disturbance.
Mitchell, however, says turbines should not be sited closer than 12 km from the nearest habitation, which would put them not just out of earshot, but largely out of sight. And certainly nowhere near his property.
Simon Holmes a Court, along with Chapman, has put a lot of work into unravelling the sociology of the anti-wind movement. There has even been produced a "network analysis", a diagram of 40 or so key people and organisations, showing the multiple links between them.
Holmes a Court can recite a sort of genealogy of the conservative establishment in Victoria — up to and including Premier Ted Baillieu — who have worked to stop wind-farm construction near their "special spots on the planet".
Their opposition, in his view, has nothing whatever to do with health issues. It's pure NIMBY-ism. They don't want bloody great turbines spoiling their idyllic views.
He believes it is very much a matter of partisan politics.
"Every Labor state government has decided they [wind turbines] are a good thing; every conservative government has decided they are a bad thing."
Holmes a Court says he sees signs of American Tea Party-style "astroturfing" in the way the anti-wind-farm lobby constructed — a not unreasonable conclusion to draw given the involvement of the likes of Cory Bernardi, the Institute of Public Affairs, and their United States associates further up the chain of denialists and wind-power opponents.
"They have a model — the Karl Rovian model really — of creating outrage through a denial of science or denial of critical thinking or a denial of calm discourse.
"It's incredibly effective, but we end up with a crap society as a result," Holmes a Court says.
How crappy? According to one recent estimate, coal-fired power causes lung, heart and nervous-system diseases which cost Australia $2.6 billion a year, while the health cost of pollution from oil-fuelled vehicles is $3.3 billion a year.
In any case, the analysis shows a remarkably incestuous group of people with overlapping involvement in Waubra, the Landscape Guardians, and conservative think tanks, particularly the IPA, the AEF and the Liberal Party.
"I would be surprised if Landscape Guardians is actually more than about 50 core people," says Holmes a Court.
"But they've got a huge footprint because every time they hold a town-hall meeting, 50 or so people come along and shout and scream."
He also obtained — and presented to a Senate inquiry into wind power a couple of years ago — a damaging email from the head of the AEF, offering logistical help to the Guardians in organising protest action. Holmes a Court also presented photographic evidence of violence at the ensuing protest.
(The inquiry was a hotly contested but inconclusive one; it received 535 pro-wind submissions and 468 anti-wind submissions, and its ultimate decision was that more research was necessary.)
Holmes a Court told the inquiry: "The email is basically a run sheet for the protest and includes the artwork for the signage held by the rent-a-crowd you will see in the photo."
"It was an ugly protest... Cars were beaten with placards. Cars were shaken. My children heard a man yell, 'I hope you all die of cancer,'" he said.
Holmes a Court called the protesters "rent-a-crowd", but it's quite likely many are just people frightened about the perceived health problems wind turbines might cause their families, and the possible decrease nearby wind farms might cause in the value of their properties.
The alleged evidence of the deleterious health effects of wind farms is regularly presented in detail to community meetings by another doctor, albeit a non-practising one — Sarah Laurie. She also became active after a wind farm was proposed near her home in South Australia.
She is the CEO of Waubra. The interesting thing about Laurie is that she is not at all like most of the other people behind the anti-wind movement. She is not a climate change denier. She is not a member of the wealthy establishment, she is not a political conservative; indeed she readily admits to being something of a leftie. She is the kind of person all such movements need — someone fired by an almost religious conviction about their particular issue, be it fluoride in the water or sugar in kids' diets, or wind power.
Laurie is a zealous and implacable believer in the manifold dangers of turbines.
And she's concerned not just about wind turbines, but also about other industrial sources of infrasound. And coal-seam gas exploration. And corporations in general. And she has a point. There is no reason to assume the corporate developers behind most wind farms are any more concerned with the effects on local communities than any other big corporations are, when local concerns are at odds with maximising value for shareholders.
Laurie is full of anecdotes about people driven to such despair by their fear of, or experience of, infrasound that they have abandoned their properties.
Even Holmes a Court, who dismisses most of the leaders of the anti-wind movement as cynically manipulative NIMBYs, concedes she is sincere.
"Sarah Laurie is absolutely genuine," he says.
And so are most people now concerned about wind turbines. They are genuinely, but not necessarily rationally, concerned.
And that's the essential problem here. There are rational arguments to be had about the siting of wind farms, but this issue has gone way past the point of rational discourse.
And it's gone that way because of a very successful scare campaign by people who would rather hide their real motives.
See Part One of this story for more on the bitter disputes over wind power in Australia.
And read more from The Global Mail on the mine that's just been approved in a critically endangered habitat, and the former adviser to John Howard fighting Woodside Petroleum over its plans for a $40 billion gas hub in the Kimberley.


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What a shambles! Luton had done their homework and knew exactly how to contain us. We had no plan B. I think if we'd played for a week we wouldn't have scored.
Saturday, January 26, 2013


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WisdomTree Japan Hedged Equity Fund (DXJ) Surpasses $2 Billion In Assets
NEW YORK, Jan. 22, 2013 (GLOBE NEWSWIRE) -- WisdomTree (Nasdaq:WETF), an exchange-traded fund ("ETF") sponsor and asset manager, today announced the WisdomTree Japan Hedged Equity Fund (DXJ) recently surpassed $2 billion in assets, more than doubling its assets in just under a month. DXJ is designed to offer broad exposure to the Japanese equity market – with a tilt toward the exporters, who may stand to benefit from a depreciating yen – while hedging the currency fluctuations between the value of the Japanese yen to the U.S. dollar.
Jeremy Schwartz, WisdomTree Director of Research, commented, "Newly elected Prime Minister Shinzo Abe has been very effective through his plans and aggressive rhetoric to weaken the yen, and as a result, there has already been improved market sentiment in the world's third largest economy 1."
Mr. Schwartz added, "I believe DXJ offers the best tactical tool for gaining access to a country that possesses a strong negative correlation, or relationship, between its currency and its equity markets. DXJ attempts to remove one element of risk – fluctuations of the yen's exchange rate versus the U.S. dollar – from the equation, thus, creating the potential for a strategic place in an investor's portfolio should the yen further weaken or even stabilize in value over the long term." View standardized performance here.
Investors should carefully consider the investment objectives, risks, charges and expenses of the Funds before investing. To obtain a prospectus containing this and other important information, call 866-909-9473 or visit wisdomtree.com. Read the prospectus carefully before investing. There are risks associated with investing, including possible loss of principal. Foreign investing involves special risks, such as risk of loss from currency fluctuation or political or economic uncertainty. The Fund focuses its investments in Japan, thereby increasing the impact of events and developments in Japan that can adversely affect performance. Investments in currency involve additional special risks, such as credit risk, interest rate fluctuations, derivative investments which can be volatile and may be less liquid than other securities, and more sensitive to the effect of varied economic conditions. As this Fund can have a high concentration in some issuers, the Fund can be adversely impacted by changes affecting those issuers. Please read the Fund's prospectus for specific details regarding the Fund's risk profile.Check Out Our Best Services for Investors
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For many years I have had a desire to bring beautiful music to Israel to bring peace and comfort to the people of the land. As an opera singer, I acquired a vision many years ago to bring international classical musicians to Israel. This vision is still burning within me....
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Discarding the traditional "box" design, the Class R Series features an ultra-shallow profile that can be easily recessed into a condensed plenum. Available in two housings—the Class R1 with a 1 3/4-inch depth (shown) and the Class R2 with a 2 7/8-inch depth—the line is offered in three sizes: 1 foot by 4 feet, 2 feet square, and 2 feet by 4 feet. It can take one, two, or three T5 lamps and comes with four shielding options.
Two additions have been made to the Light Fields product line—a 1x1 recessed fixture and a 2x2 surface-mounted fixture—providing ease of specification and more flexibility. Each luminaire is equipped with a micro-pyramidal optic that offers excellent glare control and a shallow housing of clear anodized aluminum creates a clean, minimalist look. Available for lay-in, slot-grid, or concealed ceilings, the line (depending on fixture) takes T5, T5HO, and compact fluorescent lamps.
With energy savings, environmental sustainability, enhanced spaciousness, and economics in mind, the ES8 (shown) and ES8 Relight fixtures fuse high-performance T8 technology with an efficient distribution of light. Made from recyclable steel, the fixtures use just two lamps, which, according to the company, provides up to 67 percent energy savings in comparison with four-lamp T12 fixtures. The ES8 Relight fixtures eliminate the hassle of full-fixture replacement and are installed using existing fixture housings.
This energy-efficient, high-performance, disc-shaped pendant features a choice of rotatable uplight/downlight combinations in a contemporary, industrial-derived design. A single, rigid stem is finished to match the fixture housing and is available in a selection of lengths. Aircraft cable mounts also are offered. Illumination is provided by compact or biaxial fluorescents and a variety of lens options are available.
A unique lighting system that allows users to vary light direction with a simple twist of the wrist, NoLimit is slender and simple. Offering a wide range of illumination possibilities, the system is connected by a multifunction cube that joins the 4-foot lighting elements and allows them to rotate. Each lighting element contains an ultra-slim ballast and a T5 or T5HO lamp shielded by a satin diffuser. ADA-compliant wall-mount configurations also are available.
Designed with classrooms in mind, Radi-X combines a traditional steel fixture body with a new baffle material called LiteCycle resin, which consists of 50-percent-recycled (and 100-percent-recyclable) content. It provides direct/indirect illumination from two or three lamps, has an integrated daylight harvesting system, and is Cradle-to-Cradle Silver Certified.
The Stile series includes three unique and dramatic designs: Beam (shown), Bow, and Brace. Ideal for contemporary spaces, each luminaire is offered with integral and remote emergency lighting options and can be accented with various shielding styles. Using T5 and T5HO lamping technology with an LED option in the Beam and Bow styles, Stile provides energy-efficient illumination for a variety of applications.
A versatile series of suspended and wall-mounted luminaires, Extrudo is offered in sizes up to 7 1/2 feet in length and contains gimbal rings that can be pulled down, rotated, and tilted for precise aiming. Single, double, and triple configurations of light rings (with PAR lamps) embedded in laser-cut thick tempered clear glass can be combined with a 24W or 29W linear fluorescent center.
The Bruno collection features low-profile shapes, clean lines, and subtle light elements in a range of options—such as side and bottom perforations and downlights—for a variety of appearances and light distribution choices. Constructed of cold-rolled steel, the modular fixtures measure 8 inches wide and 2 inches deep and come in lengths of 4 and 8 feet. They can take T5, T5HO, or T8 lamps and come standard in white polyester powder paint.
A family of configurable segments—including arcs, circles, and ellipses—to create unique shapes, Infinity Art is constructed of extruded-aluminum side panels with architectural reveal and a fabricated housing bottom. Containing an optically enhanced LED source, available in amber, blue, green, neutral white, and red, the fixture also has an adjustable accent light available in LED and halogen sources with a 25-degree beam spread.
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What should I do if my child falls and hits a tooth?
Your child is bound to fall on his face once in a while as he plays and tests his physical prowess. Occasionally he may hit a tooth.
First you'll want to make sure that he has no other injuries (to his face or head, for example) that need emergency treatment. If he does, call 911.
If his gums are bleeding, apply pressure with a piece of wet gauze for few minutes (or until the bleeding stops). A frozen juice pop can limit the swelling and has the added benefit of taking your child's mind off the pain. Over the next week, watch for signs of infection, such as fever or swelling and tenderness, and call the doctor or dentist immediately if you see anything unusual with your child's gums or teeth.
Should I take my child to the dentist if he hits a tooth?
If your child's teeth and gums look just fine and he doesn't seem to be in any pain, he should be okay without a dental check. If a tooth seems out of place, though, you'll want to have a dentist look at it to evaluate whether it needs to be repositioned.
If a tooth is badly chipped, take your child to the dentist right away. Bring the piece of tooth along if you can find it. (You may also want to apply a cold compress to your child's mouth to prevent swelling.) Even if the chip is small and it doesn't seem to be bothering your child, you'll want to schedule an appointment with a dentist. She can evaluate whether there are underlying cracks or other damage you can't see. She can also repair the tooth by filing it or by patching it with bonding material.
What should I do if my child knocks out one of his teeth?
If he knocks out a baby tooth, don't worry — a permanent tooth will eventually grow in its place. Baby teeth are important because they help your child eat and speak and because they hold a spot in your child's mouth for his permanent teeth to come in properly. See the dentist to make sure that no underlying teeth were damaged and that the permanent tooth will have enough space to grow in properly.
If your child loses a permanent tooth, find the tooth if you can and rinse it gently in water. (Don't scrub it or you may remove important tissue fragments and roots.) If possible, insert it back in your child's tooth socket and hold it there. Then go to the dentist's office. (If it's after hours, call the dentist's emergency number to find out where to go for emergency dental treatment.) If you can't get the tooth back in your child's mouth, put it in milk and take it with you. Not sure if it's a baby tooth or a permanent tooth? Proceed as if it's a permanent tooth, just to be on the safe side.
Will the dentist be able to put the knocked-out tooth back in?
The quicker you get to the dentist (hopefully less than 30 minutes), the better the chances. The dentist will clean your child's mouth and try to put the tooth back in place. She may also put a splint on the tooth to keep it in position until the root takes hold. During this time, your child may need to be on a soft diet, at least initially, and he may need to take an antibiotic. The dentist will take another look at the tooth in a week or so to see if the splint can come off, and she'll continue to evaluate the tooth periodically. If the root doesn't take hold, sometimes a special kind of root canal can help.
How can I keep my child from hurting his teeth?
You can't completely prevent accidents, but you can help a lot by taking these precautions:
- Make sure that your child wears a mouth guard when he plays contact sports.
- Teach your child to use caution when drinking from water fountains — it's easy to bump a tooth on the metal water jet.
- Teach your child to play safely on outdoor equipment, giving other children plenty of room. Tell him not to stand behind swings, for example, and not to pass other children on climbing equipment or water slides (two-thirds of water-slide injuries result in oral trauma).
- Always make sure your child is buckled up properly in his booster seat or seat belt.
- If your child has front teeth that protrude, have them evaluated by your dentist or an orthodontist. Teeth that protrude are more vulnerable than those that don't.
- Teach your child not to run with hard objects (like a lollipop or a toothbrush) in his mouth.


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England Crowned ICC
World Twenty20 Champions
Featured News | 16th May 2010
Nottinghamshire bowler Ryan Sidebottom took two wickets as England beat Australia to be crowned ICC World Twenty20 Champions.
Sidebottom was one of five Notts players to feature in the match with Graeme Swann claiming the prized wicket of Michael Clarke.
David Hussey, who will join Notts in early June, top-scored for Australia with 59 before he was athletically caught by Stuart Broad.
Needing 148 runs to win, Craig Kieswetter (63) and Kevin Pietersen (47) helped England cruise to their target with three overs to spare.
�I�ve had a great week and it�s due to the efforts of all of the lads�, said Kevin Pietersen who scored 238 runs in the tournament.
�It�s so good to be part of a dressing room where everybody works hard and is deserving of this success.
�This team is hungry for success and we work hard and strive for success in every training session.
�Playing against Australia is never easy because they have got some fantastic bowlers. You have to try and target every bowler and we got the better of them today.�
Dirk Nannes was the leading wicket-taker in the tournament with 14 and will arrive in Nottinghamshire on Wednesday to train with his new team mates ahead of the Friends Provident t20.


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Entries in 'atari' (13)
Atari 're-imagines' Asteroids with new open-world PC survival game
Not shy of reinvention, Atari is taking one of its classic arcade IPs and doing something different. Very different.
Atari announces Alone in the Dark: Illumination
The Alone in the Dark IP is making a return.
Alone in the Dark, Haunted House reboots heading to PC this fall
Atari has announced reboots for survival horror classics Alone in the Dark and Haunted House will release later this year.
Atari returns as 'interactive entertainment production' company
Atari Interactive has detailed plans to resurrect itself AGAIN, this time as an "interactive entertainment production company," with a focus on licensing, digital games, online gambling and more.
'Atari is a hardware brand' new CEO asserts
The Atari brand means many things to many people, but above all else it remains a hardware brand.
"I did that!" - James Heller said he was the man who buried all those ET cartridges
The man who was responsible for burying huge numbers of Atari 2600 cartridges in the New Mexico desert has revealed himself.
Atari landfill confirmed as dig uncovers E.T. cartridges
Copies of 1982 release E.T. The Extra-Terrestrial have been literally unearthed from the New Mexico landfill Atari allegedly buried them in.
Atari now says the future is digital and on mobile
Another week, another new direction for Atari.
Microsoft granted approval to excavate Atari's fabled ET dump site
The planned excavation of the fabled Atari dump site said to be filled with thousands of copies of ET The Extraterrestrial game cartridges has overcome its latest hurdle.
Atari documentary series to debut exclusively on Xbox in 2014
Xbox Entertainment Studios has announced it will be debuting a documentary series about Atari on Microsoft's consles next year.
Atari to exit bankruptcy
A U.S. judge has approved Atari's plan to leave bankruptcy protection a little less than a year after filing for Chapter 11 in January.
Outcast dev acquires IP from Atari
Appeal S.A, has purchased the rights to Outcast from Atari Europe.
Nordic Games acquires Desperados and Silver IPs from Atari
Growing publisher Nordic Games has moved to acquire yet more IP.


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Oil prices, world markets affected by Japanese quake
(Read article summary)Oil prices have dropped, and currencies in Japan, China, and Singapore will be affected.
Seth Wenig / AP
The currency markets stuck to their established pattern on Thursday with the dollar pushing up versus the majority of the majors. As you have undoubtedly heard by now, Japan was rocked with an 8.9 magnitude earthquake and slammed by a tsunami shortly after. This is the news that is dominating the markets, so I will break from my usual pattern of talking about the US first, and instead, begin in the west and work my way east.
The earthquake, which shook Northern Japan during their afternoon was the worst quake to hit Japan in over 300 years. The quake generated a Tsunami that slammed into the northeast coast of Japan causing additional damage. Surprisingly, the Japanese yen (JPY) rallied after the quake. This seems to be counter to what you would expect, as you would expect any catastrophic event to have a negative impact on the victims' currency. The quake that hit Christchurch, New Zealand is a good example, as the kiwi (NZD) has been sinking ever since it hit. But the Japanese yen rallied. After digging a bit, I uncovered what seems to be the reason. Japanese investors are big savers, but rates in Japan have been near zero for over a decade. These Japanese investors have invested their savings into foreign markets, including the higher yielding currencies of New Zealand and Australia (AUD). But this natural disaster has caused these Japanese investors to bring their currency back home, as they fear they will need it to help rebuild. And this repatriation of funds has been even more pronounced for Japanese companies who are moving their reserves back into their home currency.
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