text:
Shuttle Discovery on track for Sunday launch, unless...
On March 12, NASA managersscrubbed the launch of Discovery and its seven-member crew to the International Space Station. Now managers say they are shooting for a launch Sunday evening.
The reason for the scrub: a leaky valve at the fuel-tank end of a line that draws excess hydrogen gas out of the tank to be burned off at the end of a tall pipe some distance from the launch pad. You can read more about the particulars behind the delay here.
Have they found out why the valve gave them trouble and fixed it? No. They'll certainly try to. During a briefing this morning, launch director Mike Leinbach expressed confidence that engineers will identify the problem before launch.
But just to be sure Discovery stands a fighting chance of launching on time to achieve most of its objectives, mission managers have decided to replace the balky valve. The mission's major task is to install the station's final set of solar panels.
"If we can't find the smoking gun, it will be declared an unexplained anomoly, " Mr. Leinbach said.
Because it must rendezvous with the space station, Discovery is on a tight schedule. Because of the orbits involved, that means it has only a small window each month in which to launch.

subset: commoncrawl


text:
We hear a lot about vitamins and minerals such as B12, folate, magnesium, vitamin C, and so on, but there seems very little talk these days on the importance of dietary lecithin and choline. Are you consuming an adequate amount of acetylcholine, or other phospholipids? The odds are that you are not.
A little bit about choline
The human body produces choline by methylation of phosphatidylethanolamine (from dietary sources such as lecithin and others) to form phosphatidylcholine in the liver by the PEMT enzyme. Phosphatidylcholine may also be consumed in the diet or by supplementation. Choline is oxidized to betaine which acts as an important methyl donor and osmolyte.
For those wanting to see how this relates to the methylation cycle, below is a nice graphic (courtesy of Wikipedia).
It is well known that magnesium deficiency is widespread (57% of the population does not meet the U.S. RDA according to the USDA), but the numbers for choline deficiency are even more shocking.
According the National Health and Nutrition Examination Survey (NHANES) in 2003-2004, only about 10% of the population have an adequate intake of choline. This means about 90% of the population consumes a diet deficient in choline. Furthermore, those without an adequate intake of choline may not have symptoms.
Along with folate and B12 deficiency, inadequate consumption of choline can lead to high homocysteine and all the risks associated with hyperhomocysteinaemia, such as cardiovascular disease, neuropsychiatric illness (Alzheimer's disease, schizophrenia) and osteoporosis. Inadequate choline intake can also lead to fatty liver or non-alcoholic fatty liver disease (NAFLD).
The most common symptoms of choline deficiency are fatty liver and/or hemorrhagic kidney necrosis. Consuming choline rich foods usually relieve these deficiency symptoms. Diagnosing fatty liver isn't as simple as running ALT and AST since nearly 80% of people with fatty liver have normal levels of these enzymes according to a population study published in the journal Hepatology. In fact, in an experiment, 10 women were fed a diet low in choline. Nine developed fatty liver and only one had elevated liver enzymes.
For those who are genotyped by 23andMe, there is a SNP (rs7946) related to NAFLD you can look at in the PEMT gene called PEMT G523A (V175M). Caucasians with nonalcoholic fatty liver are more likely to carry the rs7946 (T), with the effect being most pronounced for rs7946(T;T) genotypes. [PMID 16051693]
If you are genotyped by 23andMe, make sure you are logged in to 23andMe and you will see your results for this SNP.
Choline, the nervous system, and the heart
Despite it's role in the CNS and stimulating parasympathetic activity, there is very little info about choline and mental illness. However, in a large population-based study published in The American Journal of Clinical Nutrition, people with higher blood levels of choline had lower levels of anxiety – however, levels of choline did not correlate with depressive symptoms.
Despite the lack of studies, it has been clinically observed that supplementing Lecithin or putting patients on a Lecithin rich diet can lower levels of anxiety, help the nervous system by establishing balance between sympathetic and parasympathetic, and even manage cardiac dysrhthmias. The Milner Acetylcholine Protocol (MAP) uses lecithin to manage cardiac dysrhthmias.
Phospholipids and the cell membrane
The fundamental building blocks of all cell membranes are phospholipids. Lecithin consists of phospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, Phosphatidic acid, other minor phospholipids and glycolipids. About 50% of the mass of most cell membranes are composed of phospholipids. The plasma membranes of cells also contain glycolipids and cholesterol – which correspond to about 40% of the total lipid molecules. Adequate intake of phospholipids and glycolipids is important for the integrity of the cell membranes. Lecithin contains a balanced amount of phospholipids and glycolipids.
Phospholipid supplementation has also been shown to help with mitochondrial dysfunction in patients with diseases such as Chronic Fatigue Syndrome, chronic Lyme Disease, Fibromyalgia, and Gulf War Illness. Fatigue reduced about 40% in Chronic Fatigue Syndrome patients after lipid replacement therapy (supplementing phospholipids) according to the Journal of Chronic Fatigue Syndrome.
Adequate intake of choline and choline-rich foods
Adequate intake of choline varies by age. Here is a table by CholineInfo.org.
Population | Adequate Intake (AI) |
Infants:(0-6 months) (7-12 months) | 125 milligrams 150 milligrams |
Children:(1-3 years) (4-8 years) (9-13 years) | 200 milligrams 250 milligrams 375 milligrams |
Adolescents:(14-18 years) | 400 milligrams (Females) 550 milligrams (Males) |
Adults:(19 and older) | 425 milligrams (Females) 550 milligrams (Males) |
Pregnant women | 450 milligrams |
Breastfeeding women | 550 milligrams |
CholineInfo.org also has a very nice graphic showing the best sources of choline. According to their chart, beef liver and egg are by far the best sources for lecithin with modest amounts in lean beef, chicken breast, cod, wheat germ, and cauliflower.
Unfortunately, not all nutrition data is the same, and for the sake of comparison, below is what Wikipedia lists as high choline foods.
Since cooking eggs at high temperatures destroys the choline content, it's best to cook the egg so the yolk is runny to preserve lecithin content. For people without egg allergies, properly cooked eggs is one of the best sources of lecithin.
In presence of an egg allergy, consuming liver or supplementing with sunflower lecithin may be the best options to ensure an adequate intake of choline. Sunflower lecithin may be a better source for lecithin than soy because unlike soy lecithin, sunflower lecithin is never derived from GMO crops. Also, soy is generally more allergenic than sunflower, so soy lecithin could potentially provoke unwanted effects in sensitive individuals.
Acetylcholine, phospholipids, autoantibodies, and a word of caution
Acetylcholine and antiphospholipid autoantibodies are seen in various autoimmune and chronic illnesses. It is well know that with Myasthenia Gravis, patients most commonly have autoantibodies against nicotinic acetylcholine receptor (nAChR). A large number of CFS patients may have acetylcholine receptor antibodies according to a study published in the International Journal of Molecular Medicine.
Dysautonomia and POTS can also be associated with autoantibodies against acetylcholine receptors. Mayo medical laboratories has a very comprehensive Autoimmune Dysautonomia Evaluation lab test that tests for autoantibodies against acetylcholine receptors and much more.
Antiphospholipid Syndrome (or Hughes syndrome) is an autoimmune condition that can lead to hypercoagulation and blood clots. Conditions such as Lupus, Sjogren's syndrome, Chronic Fatigue Syndrome, and Fibromyalgia are often associated with antiphospholipid antibodies. Antiphospholipid antibodies can even develop in presence of chronic infections such as Hepatitis C, Syphilis, Chlamydia pneumoniae, EBV, HHV-6, Lyme disease, mycoplasma, Q Fever, and many other infections. Antiphospholipid syndrome can be tested for with LabCorp's Thrombotic Risk Profile.
At this time there is insufficient evidence to determine if supplementing lecithin would be beneficial or harmful for those with acetylcholine receptor autoantibodies or antiphospholipid syndrome. More clinical research is needed to understand how lecithin supplementation influences the various autoimmune processes that may exist in these patients.
Whether you are a health expert with experience utilizing choline rich foods or lecithin supplements to treat chronic illness, or a patient using choline to promote your own health, please share your experience below.
This article was particularly interesting to me as I have been diagnosed with Lyme and CFS in the past and also have Myasthenia Gravis, POTS/Dysautomnia as well as heterozygous for the MTHFR gene, which I've begun to suspect plays a role in my diseases and perhaps this as well. Thanks for the valuable info!
Thanks for the good information. You may also want to add some information about cystic fibrosis and choline. There's been some interesting papers from British Columbia on this topic. Thanks for the reference to the papers on chronic fatigue. Very helpful.
Susan – If I were to include all info there is about choline, I might as well write a book. But interesting note about cystic fibrosis. A little research shows that they can have high homocysteine and tend to have low glutathione too. And choline can improve homocysteine and glutahtione in cystic fibrosis patients. There is a lot of talk about using B12 and Folate to reduce homocysteine, with not as much talk about how prevalent choline deficiency is. Choline lowers homocysteine. And like folate, it turns into an important methyl donor when it is oxidized into betaine.
Interesting history Melissa. Were you ever tested for acetylcholine receptor autoantibodies or antiphospholipid antibodies?
I have several biggie mutations in the methylation cycle and have been on various vitamins and supplements for several years with mixed results. I started on 1 Tbsp per day of liquid soy lecithin back in the spring, and there was an almost immediate and very noticeable difference in my anxiety level, chronic constipation, and focusing issues. Despite being in the gifted program as a kid and having a high IQ, I have always been frustrated with my attention level and ability to finish what I start (didn't finish HS on time, dropped out/kicked out of college multiple times 10 years ago). I am now taking college classes and getting all A's. In the middle of summer semester I ran out of lecithin and kept meaning to pick some up and didn't really make it a priority, but for the 2 weeks I was off of it I would just sit in front of the computer, unable to complete the papers I had to write. That spaciness and lack of focus went away as soon as I restarted the supplement. I've tried citicoline and a normal choline/inositol supplement, and they both made me nutty. Lecithin doesn't do that. Tastes like crap and the texture is nasty but I can choke it down if it gets me through school. : )
I have Dysautonomia (hyperMCAS POTS and NCS/NMH) plus a host of comorbid conditions. I am a 'no call' on this allele. Any suggestions?
Shae – A no call for that gene probably means that 23andMe had trouble genotyping that part or area of your DNA. So there are no conclusions you can draw from that.
However, it's just a single gene and it's not determinant of fatty liver or choline deficiency. It just increases odds of developing fatty liver which can be caused by choline deficiency.
I don't give medical advice, but do you eat eggs? Some may do well with them, some potentially worse depending on autoantibodies and allergies. Nevertheless, most otherwise healthy people do not get enough lecithin as described in the post.
POTS can be caused by acetylcholine dysregulation and acetylcholine receptor antibodies and many other things. What to do in that case isn't clear to me, but a good POTS specialist (found at dinet.org) usually knows how to test for these things and what to do about them.
I love eggs. Unfortunately, I'm a complicated zebra…I can't take the typical Meds, and have unfortunate comorbidities. Kinda hosed, basically. I'm also hyperMCAS POTS (extremely rare subset of hyper POTS) as well as NCS/NMH, so it gets complicated, indeed. I know several of my COMT SNPs carry mutations.
I got a prenatal diagnosis of trisomy 21 for my last child and read a study in a mouse model of T21 where pre- and perinatal choline improved symptoms. I started 3 g/day choline at ~20 weeks and my now 8 month old was born with no major health issues and is progressing age appropriately in terms of meeting milestones. We have continued choline during breastfeeding. I would love to find out the level of methylation on my son's 21st chromosome as I'm sure that the high dose choline has decreased the severity of effects from the additional chromosome.
the snp you named above for pemt is the one my results say is the normal one TT and shows green not red colored like the mthfr.
Why would the wild type normal be a higher risk for fatty liver?
First, the wild type isn't always beneficial. Second, it is the wild type for caucasians, but not for most other ethnicities.
Digging a bit more before this comment, it doesn't appear that there is universal agreement that this SNP increases risk of NAFLD. However, caucasians with NAFLD appear to be more likely to be TT. Confusing indeed!
Great article but I think there is an error.
We are only interested in the raw egg yolk portion of the egg which would be about 17 grams. This means there is roughly 116 mg of lecithin per raw egg yolk and not 389 mg.
James – thank you for your correction. Will correct the article.
I am diagnosed with myasthenia gravis.and undergone post thymectomy. Can I use this lecithin as a supplement. Will I see any improvement in my situation. Thanks in advance.
I have been having some intermittent ptosis (eyelid drooping) and myasthenia gravis was suggested as a possibility. I put together several conversations about myasthenia gravis with a word I remembered from my detox report "acetylation", so I ran my 23andme results for PEMT and I am +/+ homozygous TT for the rs7946 and also rs4646408 is +/+ TT as well. Of the rest of the PEMT there are 22 heterozygous, 10 normal, and 13 not genotyped. According to my detox report I am probably a slow acetylator since I have NAT2 R197Q rs1799930 AA +/+. Also in the detox report are CYP1B1 L432V rs1056836 GG +/+ and CYP1B1 N453S rs1800440 CC +/+ but I'm not sure if that has an impact on acetylcholine or not. Myasthenia gravis is an autoimmune disease. In myasthenia gravis, antibodies block, alter, or destroy the receptors for acetylcholine at the neuromuscular junction, which prevents the muscle contraction from occurring. I have autoimmune diseases already which automatically makes me susceptible to others.
Am I correct in thinking that these gene defects regarding acetylation would mean that I have less acetylcholine in the first place? If so it would seem to me that antibodies further blocking receptors for what little there is might bring on symptoms or exacerbate them.
I was having an episode of ptosis yesterday and I find it interesting/strange that I had a craving for fried eggs with runny yolks. I ate 5 of them. The ptosis went away later that evening. I hadn't read your article at that time but now I wonder if it was my body craving the lecithin for the choline? Also, I happen to have choline bitartrate powder… would that be beneficial to take or not?
I'm hoping to connect the dots between this and BCHE gene rs1799807, cholinesterase inhibitors, nightshade intolerance. Anne Wright has written on it.
I've had a decrease in POTS like symptoms, mysthenia gravis like symptoms, CFS/Fibromyalgia, just from eliminating Nightshade foods.
I like eggs but they seem to make me sick to my stomach, I wish I could benefit from a choline supplement I still have anxiety and memory problems.
HI Christi,
I'm not a doctor, but a patient like you. I've also found that I need to avoid nightshade foods big time or I get muscle cramps, twitching, and just overall overstimulation. High acetylcholine levels can cause anxiety as well due to that overstimulation.
I recently found a study that showed a connection between B12 deficiency and low acetylcholinesterase levels, suggesting that perhaps B12 may help increase the breakdown of acetylcholine.
The same with l-carnitine. Treatment with l-carnitine helped restore acetylcholinesterase levels in aged rats.
Not sure if the same thing occurs in humans, but it's worth noting that B12 levels are often functionally low, as are l-carnitine.
Hope this is helpful in some way.
No discussion about choline, phosphatidylcholine or lecithin (or even L-carnitine, betaine or TMG) consumption is complete without a thorough discussion of TMAO (Trimethylamine N-oxide).
There are several studies on this subject. Here is one:
Gut flora metabolism of phosphatidylcholine promotes cardiovascular… – PubMed – NCBI
As far as popular media, Dr. Oz, who used to recommend L-Carnitine supplements, has retracted that recommendation. When it comes to TMAO, there is little difference between L-Carnitine and choline supplements.
I have acetylcholine esterase deficiency. My C-reactive protein test was "7″. Do I have a higher level of inflammation or does this mean that a serious health telatefevent is imminent?


text:
Web browsing not just for smartphone users
Consumers with basic capability phones, such as those offered free by carriers, consume as much or more raw data than iPhone users, according to Internet mobility company Novarra. The vendor today published its first mobile Internet experience benchmark report studying how consumers access and use the mobile Internet on its Vision browser and mobile Internet platform. more


text:
Enter your email address and password to access your locker and member area. View your past orders, edit your stored address and account settings, and see your loyalty points. If you're not already a member, follow our easy sign up process now to take advantage of our extra benefits.
TaylorMade Ghost Manta Long Putter - Mass Appeal Without Masses Of Putts!
The Ghost Manta Long putter from TaylorMade has been designed to everyone who is looking for more forgiveness and a perfectly balanced putter. PURE ROLL technology in the face gives you great feedback after every putt. Read full description


text:
There are currently no reviews for this product.
The Blue Without You Sugar Cookie Gift Box is the perfect way to tell someone special you miss them. These Cookies From Scratch hand decorated cookie shapes include hearts, flowers, bows, cottages, and teddy bears. Each gift box contains one dozen delicious blue sugar cookie crisps. The Blue Without You Sugar Cookie Gift Box is a perfect Valentine gift or a gift anytime for someone you miss.
Looking for a last minute gift? Send a Wisconsinmade.com E-Mail Gift Certificate


text:
User talk:Themmozhi
From Wikiquote
Toditalai Vizhutandinar[edit]
I noticed that you recently created Toditalai Vizhutandinar with a long quote, then blanked the page the next day. Could you tell me why you did this? It seems like logical Wikiquote content, although it may be more suitable for Wikisource. I would appreciate your insight. Thank you for participating on Wikiquote! — Jeff Q (talk) 09:57, 23 Apr 2005 (UTC)
Could you please move Pirates Of The Caribbean to Pirates of the Caribbean: The Curse of the Black Pearl? - 18.104.22.168 02:06, 24 Apr 2005 (UTC)


text:
If you've ever made contact with a desert cactus, you can understand why more people don't want to grow them in their yard. Try using a good pair of cactus gloves to ease the pain. Angela O'Callaghan explains the hows and whys of these slow-growing, resource conserving, and well-defended desert plants. More on the Web:
Nevada Public Radio is not responsible for the content of external links.


text:
Event Name
- OR - Select an option belowWe'd argue that Anthony's has the best pizza this side of Italy - the blackened, bubbly crust is so authentic you can taste ancient culinary history in it. That's thanks to a coal-fired brick oven that cooks not only outstanding pies ($15.95 for a 12-inch, $18.95 for an 18-inch), topped with everything from broccoli rabe and arugula salad to breaded eggplant, but also roast beef for focaccia sandwiches ($7.95), chicken wings ($8.95 for ten, $14.95 for 20), and calzones ($14 for a small, $17 for a large). And Anthony's has been successful enough to prove us right: Many new locations have popped up with zero decline in quality. The menu is rounded out with a simple but fresh house salad ($8.95) and a slice of New York-style cheesecake ($4.50), both large enough for two.


text:
Absolutely stunning, this diamond eternity ring showcases perfectly matched cushion-shape diamonds set in enduring platinum.
Blue Nile has the jewelers everywhere - LA to Dallas to NYC - concerned. There is little chance to meet or beat them on quality/pricing.
Anonymous, LAS VEGAS, NV – August 2011
Blue Nile realizes that you may not know the ring size for a given finger, and we want to help. We provide a printable ring sizer that can help determine your ring size. Prior to printing, ensure that page scaling is set to "none" on your print dialog box.
The perfect balance of creativity and craftsmanship are the hallmarks of Blue Nile's Extraordinary collection.
View extraordinary


text:
Mionix Releases Naos 3200 Gaming Mouse with LED-Optical Sensor
Mionix, the Swedish manufacturer of professional high-end gaming accessories today unveiled the Mionix Naos 3200, an ergonomically designed LED-optical gaming mouse with unique features and many customization options.
"With Mionix Naos 3200 we wanted to create a high performance mouse with outstanding ergonomics at an affordable price. The Mionix Naos 3200 constitutes an important part of our product-range and is our first gaming mouse with an LED-optical sensor technology which is very popular among fps-players", says Carl Conradsson, Mionix.
The shape of the Mionix Naos 3200 is based on the same unique ergonomic concept and build-quality as Mionix Naos 5000. Equipped with only carefully selected high-end components and paired up with reliable LED-optical sensor technology, the Mionix Naos 3200 offers great accuracy and long term durability. The integrated LEDs supports extensive color options and can be configured from the software among other functions such as adjustable polling rate, dpi sensitivity, macros and many more.
Plug n Play - Completely Plug n Play, software needed only for configuration
3200 dpi LED - optical sensor - Reliable and accurate LED-optical sensor technology
Built-in memory - Bring your settings and recorded macros with you
Customizable LED light system - Personalize your mouse with your favourite color
3 steps customizable dpi in-game adjustment - Set 3 dpi values and switch easily between them in-game
7 programmable buttons - The buttons can be assigned to any key, mouse command or macro
Adjustable polling rate - Tune it all the way up to 1000Hz through the software
Availability and Pricing
Mionix Naos 3200 will be available in July 2010
Suggested retail price: 54,99


text:
What does BFFL mean in Community?
This page is about the meanings of the acronym/abbreviation/shorthand BFFL in the field in general and in the Community terminology in particular.
Find a translation for BFFL in other languages:
Select another language:
Discuss this BFFL abbreviation with the community:
Use the citation below to add this abbreviation to your bibliography:
"BFFL." Abbreviations.com. STANDS4 LLC, 2015. Web. 6 Mar. 2015. <http://www.abbreviations.com/term/375230>.
BFFL also stands for:
- Be Fit For Life
- Best Friend For Laughing
- Best Friend for Life
- Best Friends Forever Love
- Blackice Fantasy Football League
... and 1 more »
Nearby & related abbreviations:
Alternative search:
- Search Best Friends For Life on Amazon
- Search Best Friends For Life on Google


text:
Share with Friends
Statistics problems often involve comparisons between two independent sample proportions. This lesson explains how to compute probabilities associated with differences between proportions.
Suppose we have two populations with proportions equal to P1 and P2. Suppose further that we take all possible samples of size n1 and n2. And finally, suppose that the following assumptions are valid.
Given these assumptions, we know the following.
It is straightforward to derive the last bullet point, based on material covered in previous lessons. The derivation starts with a recognition that the variance of the difference between independent random variables is equal to the sum of the individual variances. Thus,
σ2d = σ2P1 - P2 = σ21 + σ22
If the populations N1 and N2 are both large relative to n1 and n2, respectively, then
σ21 = P1(1 - P1) / n1 And σ22 = P2(1 - P2) / n2
σ2d = [ P1(1 - P1) / n1 ] + [ P2(1 - P2) / n2 ] And σd = sqrt{ [ P1(1 - P1) / n1 ] + [ P2(1 - P2) / n2 ] }
In this section, we work through a sample problem to show how to apply the theory presented above. The approach presented is valid whenever we need to analyze differences between independent sample proportions. In this example, differences between proportions are modeled with a normal distribution; so we use Stat Trek's Normal Distribution Calculator to compute probabilities. The calculator is free.
The normal calculator solves common statistical problems, based on the normal distribution. The calculator computes cumulative probabilities, based on three simple inputs. Simple instructions guide you quickly to an accurate solution. If anything is unclear, frequently-asked questions and sample problems provide straightforward explanations. Access this free calculator from the Stat Tables tab, which appears in the header of every Stat Trek web page.
Problem 1
In one state, 52% of the voters are Republicans, and 48% are Democrats. In a second state, 47% of the voters are Republicans, and 53% are Democrats. Suppose 100 voters are surveyed from each state. Assume the survey uses simple random sampling.
What is the probability that the survey will show a greater percentage of Republican voters in the second state than in the first state?
The correct answer is C. For this analysis, let P1 = the proportion of Republican voters in the first state, P2 = the proportion of Republican voters in the second state, p1 = the proportion of Republican voters in the sample from the first state, and p2 = the proportion of Republican voters in the sample from the second state. The number of voters sampled from the first state (n1) = 100, and the number of voters sampled from the second state (n2) = 100.
The solution involves four steps.
Therefore, the probability that the survey will show a greater percentage of Republican voters in the second state than in the first state is 0.24.
■ Variables
■ Central tendency
■ Variability
■ Measures of position
■ Patterns in data
■ Dotplots
■ Histograms
■ Stemplots
■ Boxplots
■ Cumulative plots
■ Scatterplots
■ Comparing plots
■ One-way tables
■ Two-way tables
■ Sets and subsets
■ Stat experiments
■ Counting data points
■ What is probability
■ Probability problems
■ Rules of probability
■ Bayes' rule
■ Types of variables
■ Distributions
■ Mean and variance
■ Independence
■ Combining
■ Transforming
■ Random sampling
■ Sampling distribution
■ Diff between props
■ Diff between means
■ Probability dist
■ Discrete/continuous
■ Binomial distribution
■ Negative binomial
■ Hypergeometric
■ Multinomial
■ Poisson
■ Normal distribution
■ Standard normal
■ Student's t
■ Chi-square
■ F distribution
■ Estimation overview
■ Standard error
■ Margin of error
■ Confidence intervals
■ Estimate proportion
■ Small samples
■ Estimate mean
■ Matched pairs
■ Hypothesis tests
■ How to test
■ Test of the mean
■ Diff between pairs
■ Test for a proportion
■ Region of acceptance
■ Power of a test
■ How to find power
■ Goodness of fit
■ Homogeneity
■ Data collection
■ Sampling methods
■ Survey sampling bias
■ Survey sampling
■ SRS analysis
■ Stratified sampling
■ Stratified analysis
■ Cluster sampling
■ CLS analysis
■ Sample size: SRS
■ Sample size: STR
■ Find right method
■ Measurement scales
■ Linear correlation
■ Linear regression
■ Regression example
■ Residual analysis
■ Transformations
■ Influential points
■ Slope estimate
■ Slope significance
■ Experiment intro
■ Experimental design
■ Simulations


text:
We seem to live in a culture today where people are more concerned with appearing to be something important rather than actually being something important.
It appears if I died, no one in the neighborhood I grew up in would notice or care. Conversely, if my dog left the house wearing a new collar, the entire neighborhood would have a conniption.
You end up choosing a career that does not really suit you. Your desire and interest slowly wane and your work suffers for it. You come to see pleasure and fulfillment as something that comes from outside your work. Because you are increasingly less engaged in your career, you fail to pay attention to changes going on in the field–you fall behind the times and pay a price for this.
At some point, I learned something important: that being ill could dissolve the uncompromising infrastructure of your young life like so many bad dreams. Instantaneously, sympathy! Others to do for you what normally you were left alone to manage! And most importantly, liberty from obligation.


text:
Rushmore screened on Sunday August 8th at Toronto Underground Cinemas as part of director Edgar Wright's Wright Stuff film series. For the last time on this blog, I beseech you to check out Wright's latest film Scott Pilgrim Vs. the World, now showing in multiplexes also showing the Expendables and Eat Pray Love everywhere.
Due to time constraints and the fact that I am far behind on these blogs, I will keep the joys of Rushmore simple. Rushmore is a brilliant dead pan comedy from a director I seem to have a love/hate relationship with. Wes Anderson has created a film that kind of works as a new genre unto itself and stands nicely alongside Ferris Bueller's Day Off. I like to call it, the reverse slacker film.
Max Fischer (Jason Schwartzman, in his first ever leading role) loves his extracurricular activities at Rushmore Academy, but seemingly detests the actual school part of things. Max doesn't seem to have many friends, but at the same time he has his hands in everything possible and is probably the most widely known person on campus. Max is a bit full of himself, but he uses everything he has at his disposal to make everything he does the biggest and best thing possible.
Max begins to have a crush on a first grade teacher (Olivia Williams) and soon finds himself embroiled in a battle for her affections (even though she wants nothing to do with him) with a much older and wealthier man played by Bill Murray. Both men act like small children and ultimately both end up alienating the woman of their dreams.
Schwartzman plays Max Fischer perfectly from Anderson and co-writer Owen Wilson's script. Max is very sure of himself, but also hopelessly naive. He is all street smarts and no book smarts, but all his street smarts comes from books that he wanted to read and not the ones he should have been reading in the first place to stave off his impending expulsion. Murray has also rarely been better, and that is saying quite a lot. He is the one who actually paid attention, but let life pass him by in the process. Their rivalry is one of the best in film history.


text:
ROGUE RIVER, Ore. — The ABC Network and "First Book" reached across the country last month to find schools in need of new books through the "Be Inspired" campaign. NewsWatch 12 asked the community to participate by nominating schools and programs deserving of new books for kids.
Southern Oregon entered more nominations than any other part of the country and two local schools received the most nominations of any in the entire nation. In fact, Rogue River Elementary School received the most nominations overall. Shady Cove Elementary came in a close second.


text:
Share your reviews,
photos and videos here!
Involvement:General (knows how to use it) - Ownership:less than 1 day
Pros:Very beautiful watch in the form of a turtle, with a long chain (like the right thing for my mom, she ordered the new year) is also very beautiful color, black and looks like an expensive item. Ticks do not hear (hear unless you can lean your ear) I think it's positive side. The clock is not in a hurry and do not be late, very happy:)
I do not see any disadvantages in this remarkable watch:)
It would be really cool if they brought in some little box and not just in the package.
I think it's the hours that will not be ashamed to give to a friend or loved one
Get great weekly deals and offers like: Collections