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From Public Housing To Legal Career Tracks
by Meagan Jordan | Jun 18, 2014 10:53 am
(2) Comments | Commenting has been closed | E-mail the Author
Posted to: Housing, Schools
Shirley-Ann Feliciano who ranked in the top 5 in her senior class at Metropolitan Business Academy, received recognition and a Kindle Tuesday along with 20 other high-school graduates who grew up in public housing.
That happened at a recognition ceremony held at the monthly Housing Authority of New Haven (HANH) commissioners' meeting on Orange Street.
Starting in the fall Feliciano will be a pre-law student at the University of New Haven. She has aspired to become a prosecuting attorney ever since she was child, looking forward to putting the bad guys away. "I feel that's the way I am going to help my community," she said.
Feliciano, who holds a GPA of 4.36, she was surprised to learned she'd cracked her school's Top 5. "I thought I was going to be top 10," she said smiling. To prepare for her journey to a legal career, Feliciano has taken prep classes such as a business law course, which helped keep her motivated.
"My mom always taught me if you work hard for something it'll be worth it at the end," said Feliciano
Tuesday's recognition and gift ceremony, the housing authority's first, honored seniors who will attend college or vocational training programs or join the military post graduation.
"We really wanted academic success for kids," said HANH Executive Director Karen DuBois-Walton. The authority has a program called HANH Believes, which provides after school homework help and support for parents to better engage their children. It also partners with programs such as New Haven Promise to better inform families of available services.
The program will keep track of the seniors as they move on, DuBois-Walton said. "We really want to support these kids as they graduate, and stay connected when they come home." She also vows to focus on the retention rate, to make sure kids are not only going to college but also staying in college.
Wilbur Cross seniors Tamara Gray, who lives at Quinnipiac Terrace, and Daejah Brown, from Farnam Courts, were both recipients. "I greatly appreciate the support," said Gray, who will attend UCONN at the Waterbury campus this fall.
Brown will attend Tiffin University in Ohio next fall. "A lot of people don't believe in people our age graduating high school," she said. She plans to major in criminal justice, with the goal of becoming a police detective.
Tags: Housing Authority of New Haven
Post a Comment
posted by: Brutus2011 on June 18, 2014 12:49pm
Congrats all…
One question though, how does one get a 4.36 GPA?
posted by: Interesting thought on June 18, 2014 5:00pm
That's a weighted GPA. Many classes, such as AP classes have higher qualitative points. My daughter has a weighted GPA of 4.43, unweighted GPA is 3.970.
Colleges will recalculate GPAs according to their scale. I hope that helps.


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Great Day Universal Zero-Turn Lawnmower Canopy
Don't let a couple of hours of zipping around on a riding lawnmower develop into a "cookout" - with you being the one on the grill! With Great Day's Big-Top Canopy, mowing the lawn is always a "shady deal". No more worrying about heat strokes and skin cancer. The Big-Top canopy measures 36" wide and 46" long and fits rollbar widths of 32 in - 36 in wide,covering and shading the operator at all times.
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The Big-Top cover is made of heavy-duty 1/8 inch, UV resistant, crack-proof polyethylene. All metal components are powder coat painted for years of dependable service. The big-Top canopy weighs only 27 lbs and ships by UPS.
Fits Ferris, Scag and all other models with roll bars.
Additional Information
Manufacturer | Great Day |

subset: commoncrawl


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Scholars A-Z
Born on 1304
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Ibn Al-Shater was an astronomer and mathematician.
Died on 1204
Abu Muhammad 'Abdallah ibn Muhammad ibn Hajjaj al-Adrini, more commonly known as Ibn al-Yasamin. As his name indicates, he was originally from a Berber tribe from the Maghreb (North Africa). Although his exact date of birth is unknown, we can reasonably place it in the second half of the twelfth cen...
Born on 830
'Abd al-Hamid Ibn Turk was a well known mathematician of the early 9th century, probably contemporary to al-Khwarizmi.
Born on 982
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Ibn Zur'a was a philosopher and translator. He was fluent in both Syriac and Arabic.
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quote:Lots of fun action, they are dwarves,
quote:Why did Smaug call Thorin, "Oakenshield"?? That nickname was earned after Smaug had taken the lonely mountain.
quote:Saw it in 2D as well. I'll go back and see it in 3D to see if that helps. I didn't like the first installment until I watched it several times.


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The Camptonville Volunteer Fire Department
Mission Statement
The Camptonville Volunteer Fire Department (CVFD) provides fire protection, rescue and emergency medical services, education in fire safety and emergency standards, and other services to protect lives and property while maintaining the highest level of safety for firefighters and rescue personnel. Services are provided in a professional manner within the economic and demographic limitations of our community and in recognition of the need for dedicated volunteer involvement, using innovation and flexibility in response to local needs and conditions.
Stay informed!Read Chief Mark Jokerst's April 2012 Report here or in the April Edition of the Camptonville Courier
Read Chief Mark Jokerst's March 2012 Report here or in the March Edition of the Camptonville Courier


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Learning Sustainability with Sim City
Sybil Hill
Sim City is a computer game that has the player design a city. They become the mayor. While designing the city from ground, they can choose sustainaiblity energy options such as wind farms, geothermal, and solar. The game includes greening options and pollution factors. Teachers in a variety of disciplines can utilize this to bring their core course concepts to life.
Unit 3: Translating the Message
Brittany Brand, Boise State University; Pamela McMullin-Messier, Central Washington University; Melissa Schlegel, College of Western Idaho
Students will identify potential stakeholders and assess the importance of communication and interaction among these groups to make recommendations on how to define and develop prepared communities.
Unit 1: Hazards, vulnerability and risk
Brittany Brand, Boise State University; Pamela McMullin-Messier, Central Washington University; Melissa Schlegel, College of Western Idaho
Students will identify and apply credible geologic and social science data sets to identify local hazards and vulnerable groups and structures, and assess risk for their community.
Environmental Footprint
Christina Gallup, University of Minnesota-Duluth
This activity has students do a web-based environmental footprint quiz and integrate their results into a class mean. The students compare their results by creating a bar graph and do some simple calculations to see how much of the Earth just the population of the US requires.
Migration: An Empathy Exercise
Maureen Ryan, Western Washington University
Migration: An Empathy Exercise is a multi-step reflective exercise designed to build empathy and personal insight into processes of loss, change, and reconnection associated with the disruption of personal and cultural connections to landscape.
What is the West?
Maureen Ryan, Western Washington University
What is the West? is a written reflective exercise, with associated readings and discussion, designed to 1) build insight into how personal experiences shape our perception of landscapes, 2) enhance knowledge of the geography and ecology of the American West, and 3) illuminate the role of water (or lack of water) in the natural and cultural history of the American West.
Old Sticks in the Mud: Hazards of Lahars from Mount Rainier Volcano
Patrick Pringle, Centralia College
Volcanic debris flows (lahars) flow long distances, bury and aggrade river valleys, and cause long-term stream disturbances and dramatic landscape changes. Students will evaluate the nature, scale, and history of ...
Making Sustainable Business Decisions In Four Different Industries and Their Effect on People (Social), Planet (Environment), and Profit (Economics)
Walt White
The student will gain a better understanding of "Global Warming" and the "Triple Bottom Line" by viewing the first two videos. Further the CEO2 game will introduce many new ideas/options that specific industries have to select from in achieving their desired corporate/company goals.
Introduction to Google Earth
Liane Stevens, Bentley University
This assignment is designed as an introductory Google Earth tutorial on navigation; layers and featured content; and the creation and modification of Placemarks, Paths, and Polygons. The assignment is intended as a ...
Our Place in the World (Long Island Series)
Glenn Richard, SUNY at Stony Brook
Our Place in the World is a hands-on Google Earth activity designed to establish a local, regional, and global geographic context in connection with a course, workshop, or field trip.


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This video is part of the following collections:
- Like
- Thanks for voting!
- Download
- Collection
Rofllmaobbq May 31, 2011
Marriage material right there!
naughty little beggar May 17, 2011
what a delicious icing on that beautiful face!
trysexual June 24, 2011
Fake or not, it's fucking hot! WIsh I could blow a load like that every tenth time or something! Can you say anal creampie fart?
gman July 21, 2011
More PLzzzzzzzzzzzzzzzzzzzzz
ist August 5, 2011
fake und so
ron August 4, 2011
I guess, the man in the video save his sperm for 90 days. because he has a lot of sperm released. :)
hihi May 6, 2011
wow!!!.....flowing sperm long lasting!!
spoon April 26, 2011
that was a little more than a teaspooon lol
kiemol February 15, 2011
fake ofcourse
dim February 8, 2011
das February 15, 2011
whos that girl
code March 6, 2011
whats the name of the girl ? i think she's filipina ?
Aueia April 15, 2011
Its real... I can do that! ;)
fake! August 8, 2011
look at my name!!!!!
no August 14, 2011
i think only porn-noobs or people who never had sex, or female who never saw a man cum think this is real. it is ofc not. overdone
sss January 22, 2013
this video use old flash player version i think
anonymous September 18, 2012
This video don't works
dude February 10, 2013
fuck March 23, 2013
somebody can upload again the video?
Me November 23, 2014
Holy fuck, that was a lot of juice!
dude July 20, 2013
where else can one find this vid?
marco marongiu July 19, 2012
@chiara beri
anonymous February 29, 2012
sexy bitch
:) September 21, 2011
Such a lucky little girl
hochiminh September 9, 2011
fake or not, its always a lovely and horny scene of a beauty eating cum
Rico October 23, 2011
What a fucking magnificent load. Every spurt (11 in all) splatters her face. I'd love to watch him unload like that on my wife's face (and then do a "Milkman"). Again, all you guys who cry "fake" when you watch an incredible display of cum like this have either never been able to do it yourself, or you never saw anybody do it. This guy is totally sexy. Delicious cumscene.
shoot master November 29, 2011
Cumwhore I would love to shoot on your face baby
misspop69 December 21, 2011
not real. i'm a cum lover, and that aint real. still hot, tho. nothin beats getting a faceload from a cock thats been rested for a week
jejeje February 6, 2011
This is a midjapan girl i know
random January 31, 2011
only because you cant cum that much, doesnt mean its fake
aajajaj July 28, 2010
jajaja was scheisse
ranten202 July 25, 2010
fake for sure
K August 17, 2010
Not real I'm afraid
why August 19, 2010
This can happen... with proper hydration and a LOT of days waited :)
Boner August 27, 2010
sos August 20, 2010
i wish he cummed fully in her mouth, she would choke!!!!anyway is that guy african????
Jnr July 25, 2010
hmmm cumwhore, you sound like a great person to be with lol
WhoGives July 17, 2010
Anyone know where to find the full video? Plz help
F*ck! June 3, 2010
Anyway, who's that girl? Anyone knows her name?
Randy B June 1, 2010
That lot should have been in her cunt, it would make for a never ending creampie
JohnnyRio June 4, 2010
fala sério... que porra é essa?
LOL June 14, 2010
Fake! He does a good job at hiding the tube and pump
l June 18, 2010
i would like to see this guy making more facial . are really sexy
no September 12, 2010
bulad September 25, 2010
fake... why would he choke his dick (points at his right hand)?? so meaning he is hiding something
milkman 2 December 30, 2010
hey milkman wtf? u licked of your friends cum of your wife's face?
Milkman December 29, 2010
I had my mate over once - we both got drunk and went and doubleteamed my wife. I remember when we woke up in the morning I went downstairs to make some coffee. Last thing I said was don't start anything without me there. When I got to the top of the stairs my wife was on her knees sucking his magnificent cock. When he saw me standing there watching them whilst slowly wanking myself off at the sight, he pulled his cock out of her mouth and dumped a load at least as big as that over her face. I just had to lick it off.
Porno January 10, 2011
LOL January 28, 2011
milkman 3 January 31, 2011
hahahaha milkman nice story ;) but are u g ? likcing the cum of your friend ? omfq wtf xDDDDDD
Fake Cummer December 8, 2010
Another tube hidden behind the cock trick.
suckmy November 23, 2010
it can't be faker
fuck September 30, 2010
fake thats not a cum its a condense
Sumit September 27, 2010
Anthanagore October 9, 2010
Fake, obviously
ouzou October 12, 2010
If cum was that thick, this cock would explode before u say "FAP".
luckynumber7 November 23, 2010
dont know if this is fake or not, but size of cumshot is very normal. personally i get like between 6-8 shots when i cum. but everyones different. some guys i know max out at 2-4 shots. not counting drippings.
Cumwhore May 31, 2010
That girl is so lucky. I wish to take of him like that or clean up her face with my tongue. His cum looks so delicious...
Loading Comments


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- Alternative Titles
- Palmer's Index to The Times (1790-1905) (DLPS version)The Official Index to the Times (1906-1980) (DLPS version)The Times IndexPalmer's Index to The Times (London)The Official Index to the Times (London)
- Description
Brief citations to articles that appeared in The Times (London) (1790-1905). Searchable by keyword in the title and/or in article main heading. Searches are combined with The Official Index to The Times (London) (1906-1980).
- Type
- Article Index
- Stable URL
- http://www.lib.umich.edu/database/link/11171
- Access


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Former Rushville police officer who worked as DARE officer admits to inappropriate relationship
Cale Worley pleads guilty to 2 counts
RUSHVILLE, Ind. - A former police officer who worked with Rushville Community Schools has pleaded guilty to having an inappropriate relationship with a teenage girl.
Cale Worley, 28, of Rushville, pleaded guilty Wednesday to official misconduct and contributing to the delinquency of a minor.
Worley, who worked as a DARE officer with the district, resigned from the department in August 2012 when state police began investigating his communications with a 15-year-old girl.
Investigators said Worley met with the girl after hours and communicated through text messages and on Facebook, talking about the girl's sex life and other topics.
In addition to his plea, Worley's credentials and certifications to be a police officer and EMT have been revoked in the state of Indiana.


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Kings Destroy
United States
Last Known Status: Active
Latest Kings Destroy News
Below is our complete Kings Destroy news coverage, including columns and articles pertaining to the band. Some articles listed may be indirectly related, such as side projects of the band members, etc.
Kings Destroy Posts New Track
New York doom act Kings Destroy is streaming an advance track, "Casse Tete," from its upcoming release "A Time For Hunting." That new release from the band will be issued on May 14th via War Crime Recordings. Stream the new single below.
Kings Destroy takes its name from the 70's Bronx graffiti crew and features guitarists Carl Porcaro and Chris Skowronski from NYC hardcore act Killing Time. Kings Destroy has also posted a small series of concert dates, which follows.
Kings Destroy on tour:
Jun. 07 Brooklyn, NY – Saint Vitus (Record Release Show w/ Clamfight, Windhand, Belus)
Jun. 20 Chicago, IL – Reggies (w/ the Swan King and Yakuza)
Jun. 21 Milwaukee, WI – Days of the Doomed Fest
June 22 Columbus, OH – Cafe Bourbon St (w/ Tank Destroyer)
Kings Destroy Reveals New Album Tracklisting
New York doom metal act Kings Destroy has revealed the tracklisting for its debut full-length album. The album, titled "And the Rest Will Surely Parish," was produced by Sanford Parker (Zoroaster, The Gates of Slumber) at Water Music Recorders in Hoboken, New Jersey.
The track listing for Kings Destroy "And the Rest Will Surely Parish" is as follows:
1. The Mounty
2. Dusty Mummy
3. The Whittler
4. Planet XXY
5. Medusa
6. Stung
7. Two Tons
8. Old Yeller
Kings Destroy Posts "Old Yeller" Video
Brooklyn's stoner/doom rock group kings Destroy has launched the band's first music video for the song "Old Yeller," which can be viewed below. "Old Yeller" comes from the band's self-released debut 7-inch EP.
"'Old Yeller' was a collaboration between a filmmaker friend of ours named Dave Danesh, and Morgan Nichols," explains vocalist Steve Murphy. "The idea surrounding it is pretty self-explanatory and goes hand-in-hand with the lyrics. The song is about how the media has been bought off by the US government, and therefore lost its way in terms of protecting our democracy as the fourth check and balance. So grab a nice cold PBR and hail the demise of our glorious nation."
Kings Destroy Streaming New Songs Online
Kings Destroy, Brooklyn's up-and-coming doom/stoner rock outfit, released their debut 7-inch EP on Tuesday. The self-titled EP was recorded by Mike Moebius at Moonlight Mile studios in Hoboken, NJ. The tracks "Old Yeller" and "Medusa" are currently available for streaming on the band's official MySpace page.
Kings Destroy played their EP release show Wednesday night at the Cake Shop in Manhattan, donating proceeds to the members of the band Torche, who were robbed while on tour in Chicago earlier this month. The band is still accepting donations for Torche, via Paypal to the email address: firstname.lastname@example.com.
The band will head into the Water Music recording studio in Hoboken, NJ this June, to record their debut full-length record with producer Sanford Parker (Yob, Pelican, Nachtmystium). The full-length is expected to be released this fall.


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- dotTech - http://dottech.org -
How to remotely locate, lock, or erase your lost or stolen Android smartphone or tablet [Guide]
Posted By DavGit On October 25, 2013 @ 10:05 AM In Android | No Comments
If you own a smartphone, you have probably wondered if there is a way to track it down if it gets lost. In some cases, it could simply mean that you misplaced it around the house and can't figure out where it is, while in other situations it may be stolen. Google has made it easy for Android phone and tablet owners to not only keep track of where their devices are located, but also to secure them if they get misplaced. In this guide, you are going to learn how you can lock your device when it is misplaced, locate, ring, or even wipe it remotely of all data if you think it has fallen into the wrong hands.
In this tip we will be describing how to use Android Device Manager, a native feature Google has built directly into Android itself.
In order to use the Android Device Manager, you need to be logged into your Google Play account, otherwise it will not be possible to access the features and services of this new tool. And ensure that your device is running Android 2.2 and above.
Before you can use Android Device Manager, you need to set it up on your device. To do that, do the following:
Done! Android Device Manager is now activated on your device.
After Android Device Manager is activated on your device, to remotely locate, ring, lock, or erase your Android device that you have misplaced, do the following:
The Android Device Manager will automatically try to locate and show you the exact location of your device on a map in real time. When you click on Ring, the device rings at maximum volume even when in silence mode.
The Android Device Manager now allows you to securely protect your data and resources from access by unauthorized person even when you have misplaced or lost your device. Google makes the service available to any 2.2 and above Android device owner who has a Gmail account and is logged into the browser for free. Enjoy!
Article printed from dotTech: http://dottech.org
URL to article: http://dottech.org/132687/how-to-locate-lock-erase-data-android-device/
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[3] http://www.google.com/android/devicemanager: http://www.google.com/android/devicemanager
Click here to print.
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Archive by Author
Breathtaking Bolivia: Our week in Potosí, the world's highest city
Posted on 24. Feb, 2014 by Jess.
Explore breathtaking (literally!) Potosi with us, the highest city in the world, colonial gem of Bolivia and once the world's richest city thanks to its silver mine.
Continue Reading
Llama trekking to the Rio Grande | New Mexico
Posted on 21. Feb, 2014 by Jess.
Trekking into the Rio Grande gorge with four llamas in tow was one of our favorite experiences in New Mexico. Read all about the hike and our awesome llamas:
Continue Reading
Striking gold in Silver City and the Gila Cliff Dwellings, New Mexico
Posted on 18. Feb, 2014 by Jess.
The first stop of our New Mexico road trip turned out to be one of our favorites. Read on to find out what makes Silver City and the Gila Wilderness so incredibly special.
Continue Reading
Aliens, llamas and cave dwellings…let us take you on a trip through New Mexico (Video)
Posted on 16. Feb, 2014 by Jess.
We're excited to tell you all about our New Mexico road trip over the next few weeks – check out this teaser video to see what to expect!
Continue Reading
The Break Free Podcast 12: Alex Baackes of AlexInWanderland.com
Posted on 02. Feb, 2014 by Jess.
Alex Baackes found out early that a corporate lifestyle wasn't for her. Listen to Session 12 find out how she found her tribe, how she hustled to create multiple income streams and how she maintains a lifestyle of location independence, a successful business and a serious case of wanderlust.
Continue Reading
How to upset an entire nation: Why Chileans Think We SUCK!
Posted on 31. Jan, 2014 by Jess.
We have angered an entire nation. Find out what we said, what we didn't say, and how the Chileans reacted…
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Polaroid of the Week: Broken in Peru
Posted on 30. Jan, 2014 by Jess.
This week's Polaroid encapsulates the short, sad story of Jess breaking her ankle in Cusco, Peru.
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GlobetrotterGirl of the Month January 2014: Drummer, Singer, Solo Artist Nico Turner
Posted on 29. Jan, 2014 by Jess.
We're kicking off the new year with the inspiring and authentic Nico Turner, who launched her solo career opening for Cat Power. Her love of the true essence of travel is contagious!
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Warming up to the Iquique coastline in Northern Chile
Posted on 19. Jan, 2014 by Jess.
Question: The more you travel, do you start to compare every new place with somewhere you've been before? We do this constantly now and not only the general feeling of a place, but even specific corners, streets and neighborhoods, too. It took us quite a while to warm up to Iquique, a city in Northern […]
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Polaroid of the week: Machu Picchu, The Lost City Of The Incas
Posted on 16. Jan, 2014 by Jess.
We finally made it to Machu Picchu, one of the biggest items on our bucket list. The ancient Inca city did not disappoint – definitely a highlight of all our travels!


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Greenville Avenue
Good Samaritan Stabbed To Death Breaking Up A Fight Will Be Remembered
A candlelight vigil is planned to honor the memory of Terrell Cowherd, 26, who was stabbed to death early Saturday morning outside Club Kush on Greenville Avenue after he tried to break up a fight.
Stabbing Suspect Turns Himself Into Dallas Police
The suspect accused of stabbing a good Samaritan who was trying to break up a fight along Greenville Avenue turned himself into police less than 24 hours after police released photos of the suspect.
Fire Destroys Former Restaurant In Dallas
Investigators were out on Monday morning looking for the cause of a three-alarm fire that destroyed a former Mexican restaurant in northeast Dallas and left one person dead.
Homeowners Prepare For St. Paddy's Day Parade Crowds
aint Patrick's Day is this weekend so that means Dallas residents living on the "M" Streets are getting ready for big crowds headed to the area for the annual parade on Greenville Avenue.
Ways For DFW Kids To Celebrate St. Patrick's Day
St. Patrick's Day is more than just green-colored brew and rowdy parades. DFW offers several family-friendly (and affordable) events that are guaranteed to be fun for kids.
3-Alarm Fire Destroys Dallas Condominium Unit
As North Texas drivers were out fighting rush hour traffic, members of Dallas Fire Rescue were out battling a 3-alarm fire. The blaze destroyed a unit at the Birchbrook II Condominiums, near Greenville Avenue and Lovers Lane.
Dallas Debates If RPOs Are The Way To Go
Resident Parking Only or RPOs started in the Greenville Avenue district several years ago. Today, RPOs can be found in five of the six entertainment districts.
Violent Crime Spree Leaves Dallas Man Possibly Paralyzed
Ryan Lusk was ending a night of celebrating St. Patrick's Day, along Dallas' Greenville Avenue. Everything changed early Sunday morning
Eye On Traffic: March 17-23
The Annual St. Patrick's Parade down Greenville Avenue is happening this Saturday, followed by a concert in Energy Square and subsequent merriment. There will also be a St. Patrick's 5K at 8 a.m. that morning […]
Dallas St. Patrick's Day Parade Brings Excitement & Dread
Some residents of Lower Greenville Avenue are embracing the prospect of huge crowds this St. Patrick's Day weekend, but others are more skeptical.
Best Dallas Pubs, Crawls & Events On St. Patty's Day
Join other emerald-clad folks in Dallas this St. Patrick's Day for some good old-fashioned beer drinking and shenanigans, and possibly a run.
Cajun Food Truck Brings 'Big Easy' To 'Big D'
A new food truck along Greenville Avenue in Dallas is bringing the taste of New Orleans to North Texas, just in time for Mardi Gras celebrations.


text: National Alliance on Mental Illness page printed from NAMI Metropolitan Baltimore Support NAMI Metropolitan BaltimoreOther Ways to Give Mail: Please send your donation to 5210 York Road, Baltimore, MD 21212 Workplace Campaigns: Choose #5697 through your United Way, MD Combined, and/or City Charitable Campaign! Employer Matching Gifts: Matching employee's gifts to NAMI: Check with your employer for forms! Donate your Car, RV, or Boat: Your donation of a car, RV, or boat is tax deductible. Click here for more information and a donation form. |


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ImmunoGen, Inc. Reports Fourth Quarter And Fiscal Year 2013 Financial Results And Provides Fiscal Year 2014 Financial Guidance And Corporate Update
ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops anticancer therapeutics using its Targeted Antibody Payload (TAP) antibody-drug conjugate (ADC) technology, today reported financial results for the three-month period and fiscal year ended June 30, 2013. ImmunoGen also provided guidance for its 2014 fiscal year and an update on the Company.
"We are starting to see the first commercial rewards from our many years of scientific innovation," commented Daniel Junius, President and CEO. "Kadcyla sales are off to a strong start in the US for its first indication, with many additional approvals expected. It is particularly gratifying to hear from patients about the difference Kadcyla is making for them and their caregivers."
Mr. Junius continued, "We're using our industry-leading technology and expertise to develop a pipeline of wholly owned compounds for cancers with significant unmet need today. We plan to meaningfully advance our clinical-stage pipeline over the course of this fiscal year, with achievements expected to include: initiation of clinical testing with our IMGN289 product candidate; presentation of additional clinical data for IMGN853; making a next-step decision for IMGN901; and having the dosing information needed to begin evaluation of our IMGN529 compound in specific non-Hodgkin's lymphoma subtypes. We also expect a number of partner-related events over the course of this fiscal year. For Kadcyla alone, we're expecting a decision about approval in the European Union and presentation of data from the TH3RESA trial within the next few months."
Product Pipeline Update
- Kadcyla is an approved product that utilizes the Company's TAP technology. It is being developed and commercialized by Roche under an agreement with ImmunoGen. ImmunoGen receives and recognizes royalties on Kadcyla sales one quarter after the sales are reported by Roche.Kadcyla gained FDA marketing approval in the US on February 22, 2013 for the treatment of people with HER2-positive metastatic breast cancer (BC) who had received prior treatment with Herceptin ® (trastuzumab) and a taxane. Roche reported "strong uptake" of Kadcyla in the US, with year-to-date sales of 82 million CHF (approximately $87 million) through June 30, 2013.Kadcyla was approved in Switzerland in May 2013, and Roche reported sales through June 30 of 1 MM CHF. Roche expects a decision about approval in the EU in 2H2013. A marketing application is also under review in Japan.Roche is assessing Kadcyla in a number of additional indications, including for first-line treatment of HER2-positive metastatic BC (MARIANNE trial), for uses in early stage HER2-positive BC (including the KATHERINE trial), and for the treatment of advanced HER2-positive stomach cancer (GATSBY trial). The progression-free survival (PFS) endpoint of TH3RESA has been met, and Roche intends to submit these data for presentation at the ESMO annual meeting Sept. 27-Oct. 1, 2013. Roche expects results from MARIANNE in late 2014 and to apply for first-line treatment of HER2-positive metastatic BC and for treatment of advanced HER2-positive gastric cancer in 2015.
- IMGN901 is ImmunoGen's lead wholly owned product candidate and is being evaluated for first-line treatment of small-cell lung cancer (SCLC). Its target, CD56, is found on a variety of cancers, including SCLC, other tumors of neuroendocrine origin, and multiple myeloma.The Company's NORTH Phase II trial is designed to assess whether the addition of IMGN901 to standard of care etoposide/carboplatin (E/C) provides a meaningful benefit over E/C alone as first-line treatment for newly diagnosed, extensive disease SCLC. The primary endpoint is progression-free survival (PFS), with objective response rate and overall survival (OS) among the secondary endpoints. Current first-line therapy for this cancer has a median PFS of 5-5.5 months and OS of 9-11 months.ImmunoGen expects to complete patient enrollment this quarter and to have the data needed to make next-step decisions for the compound by mid-2014. The Company expects NORTH clinical data will be reported at one or more medical conferences in 2014.
- IMGN853 is a potential new therapy for ovarian, endometrial, and adenocarcinoma lung cancers, as well as other cancers that overexpress its folate receptor α (FRα) target. This TAP compound is also wholly owned by ImmunoGen.The first IMGN853 clinical data were reported at the ASCO annual meeting in June 2013. They were from the dose-escalation part of the Phase I trial underway, which is designed to establish the IMGN853 dose for the expansion phase of the trial. Dose levels ranging from 0.15 to 7.0 mg/kg had been evaluated, and at the time of data cut-off for presentation, the 5.0 mg/kg dose was being further explored. Evidence of activity was reported in patients with strong FRα expression who had received IMGN853 at doses of 3.3 mg/kg or above.ImmunoGen expects to start the expansion phase of this trial later this year, and to report updated findings from it in disease-specific populations in mid-2014.
- IMGN289 is ImmunoGen's third wholly owned TAP compound for solid tumor indications, and is a potential new treatment for EGFR-positive cancers, including most squamous cell lung and head and neck cancers.In preclinical testing, IMGN289 was found to be highly active against cancer cells resistant to EGFR inhibiting agents − including tyrosine kinase inhibitors (TKIs) – as well as those responsive to EGFR inhibition. This is attributed to the ability of IMGN289 to kill cancer cells directly with its potent cytotoxic component as well as through EGFR inhibition. The IMGN289 Investigational New Drug (IND) application is now active and ImmunoGen expects to begin its clinical testing by the end of 2013.
- IMGN529 is ImmunoGen's lead wholly owned TAP compound for hematological malignancies. It is a potential treatment for CD37-positive non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukemia (CLL), and is currently in Phase I testing for NHL.
- In addition to Kadcyla, six other TAP compounds and a CD38-targeting therapeutic antibody are in clinical testing through ImmunoGen's collaborative partnerships, with additional compounds progressing preclinically.
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text:
The Blood Type Diet Archives Volume 1
Posted By: Kathy BarazDate: March 10, 1997 at 13:55:14
I am blood type O and my husband is AB. We have been taking Intra for a couple of months now. t came highly recommended by a friend of ours who has been taking it for 3 years. It contains 23 different herbs in a natural juice base. Not specified. There are no amounts listed just the dosage.(1-2 oz.per day). The herbs listed are as follows: alfalfa extract,aloe vera gel,astragalus root extract,bee pollen, capsicum fruit extract,cascara bark extract,celery seed extract, chicory root extract,chinese pearl barley extract,dandelion root extract,fenugreek, german camomille extract, ginger root extract,juniper berry extract,licorice root extract,passion flower extract,pipissewa extract,reishi mushroom extract, rose hip extract,sarsaparilla extract, schisandra berry extract,siberian ginseng extract thyme extract.From your book I know that alfalfa and aloe are on the avoid list for O types.(Also I never had a bleeding problem) Aloe is on the avoid list for AB types. Could you comment on this? Should we keep taking Intra? Kathy


text: Em 22-08-2013 11:08, Bruce Dubbs escreveu: > Fernando de Oliveira wrote: >> Three points: >> >> First one, I could do, but the other ones, I would prefer, either is a >> too important decision or it is too big for me, but if necessary, can try. >> >> 1. Minor one, but noticed it, yesterday: >> >> In the book, >> cleaning: rm -r certs BLFS-ca-bundle* >> >> However, certdata.txt is left. Is it intentional, or should be cleaned too: >> >> rm -r certs BLFS-ca-bundle certdata.txt > > That's the downloaded data. Leaving it was intentional. Do you delete > the tarballs after you install the package? Right. >> 2. Minor one, too: >> >> Never understood: wget is explicitly used, but only optional. Perhaps, >> should be placed at "Recommended" or "Required", alternatively, the >> comment "a web browser may be used instead of wget but the file will >> need to be saved with the name certdata.txt" could be closer to "Optional"? > > You can change it to Recommended. There are alternate ways to fetch the > data, but the instructions do assume wget. Done. >> 3. This, I think is important, although, can be delayed. However, it >> might be good having it for an eventual BLFS-7.4. >> >> DJ requested a "blob" with how to install or update cacerts for OJDK, in >> this page. I would like to open a ticket for us not to forget this. If >> needed, I could help. For example, if a xml could be sent to me with the >> places and some comments of the new items, and them, I could insert the >> commands. > > That's fine. You never need 'permission' to open a ticket. It can > always be closed. Since I don't do much java, I really don't have an > opinion of the OJDK cacerts, but it does seem reasonable. Done. -- []s, Fernando


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William J. Mara
Administrative Coordinator
Room L-317A, 617-638-5123 William Mara or
Billy joined the GMS team in 2014 as the administrative coordinator for the M.D./Ph.D & Ph.D programs, as well as the official liaison between the GMSSO student organization & GMS. In relation to the doctoral programs, he participates in the admissions, selection, and interview processes, and assists in the administration of graduate medical/doctoral coursework. Billy also works as an event coordinator, overseeing commencement and other GMS Division activities. A graduate of Quinnipiac University's Class of 2013, he majored in Marketing with a minor in Legal Studies, and plans to earn a masters degree in International Relations from Boston University. An outspoken Bay State Original, he has a passion for traveling as well as spending time with friends and family across the northeast, in his hometown of Andover, and in the great city of Boston.


text:
The menstrual distress questionnaire: Are the critics right?
- Ellen Hawes,
- Tian P. S. Oei
- … show all 2 hide
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The Menstrual Distress Questionnaire (MDQ) is the most widely used method of assessing premenstrual symptomatology. It is also the most frequently criticized instrument in this field. A review of the criticisms made toward the MDQ revealed three major issues concerning the reliability and validity of this instrument and the sample from whom normative data were gathered. These issues were examined in light of 49 studies that used this instrument between 1968 and 1990. Many of the criticisms were found to be justified. A marked lack of adequate research into the MDQ's reliability, problems associated with the normative sample, and uncertain validity were found. In particular, the MDQ appears to measure constructs unrelated to the menstrual cycle and define premenstrual syndrome inaccurately. In addition, the factor structure of this instrument may be unstable. These conclusions were tempered with the knowledge that the MDQ has not been utilized to its full potential in most of the research conducted to date.
- Abdel-Khalek, A.M. (1983). The Menstrual Distress Questionnaire: An exposition and Egyptian study.Research in Behaviour and Personality, 3, 13–38.
- Abplanalp, J.M., Donnelly, A.F., & Rose, R.M. (1979). Psychoendocrinology of the menstrual cycle: Enjoyment of daily activities and moods.Psychosomatic Medicine, 41(7), 587–604.
- Ainscough, C.E. (1990). Premenstrual emotional changes a prospective study of symptomatology in normal women.Journal of Psychosomatic Research, 34(1), 35–45. CrossRef
- American Psychiatric Association. (1987).Diagnostic and statistical manual for mental disorders (rev. 3rd ed.) Washington, DC: APA.
- Badamy, Y., Kamel, N., Abel-Khalek, A., & Gaafer, M. (1983). The relationship between personality and premenstrual syndrome.Research in Behaviour and Personality, 3, 59–73.
- Blatt, M., Wiesbader, H.L., & Kipperman, H. (1953). Vitamin E and Climateric Syndrome: Archives of Internal Medicine, 9:792.
- Brooks, J., Ruble, D.N., & Clarke, A.E. (1979). College women's attitudes and expectations concerning menstrual-related changes.Psychsomatic Medicine, 39, 288–298.
- Brooks-Gunn, J., & Ruble, D.N. (March, 1979).The Social and Psychological Meaning of Menarche. Paper presented at the meeting of the Society for Research in child Development, San Francisco, California.
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- Maddocks, S., Hahn, P., Moller, F., & Reid, R.L. (1986). A double-blind placebo-controlled trial of progesterone vaginal suppositories in the treatment of premenstrual syndrome.American Journal of Obstetrics and Gynaecology, 154(3), 573–581.
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- Scrambler, A., & Scrambler, G. (1985). Menstrual symptoms, attitudes and consulting behaviour.Social Science Medicine, 20(10), 1065–1068. CrossRef
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- Title
- The menstrual distress questionnaire: Are the critics right?
- Journal
Current Psychology
Volume 11, Issue 3 , pp 264-281
- Cover Date
- 1992-09-01
- Print ISSN
- 0737-8262
- Online ISSN
- 1936-4733
- Publisher
- Springer-Verlag
- Additional Links
- Topics
- Industry Sectors
- Authors
- Ellen Hawes (1)
- Tian P. S. Oei (1)
- Author Affiliations
- 1. Psychology Clinic, Department of Psychology, The University of Queensland, 4067, Brisbane, Qld, Australia


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The Saccharomyces cerevisiae Pif1p helicase is a negative regulator of telomere length that acts by removing telomerase from chromosome ends. The catalytic subunit of yeast telomerase, Est2p, is telomere associated throughout most of the cell cycle, with peaks of association in both G1 phase (when telomerase is not active) and late S/G2 phase (when telomerase is active). The G1 association of Est2p requires a specific interaction between Ku and telomerase RNA. In mutants lacking this interaction, telomeres were longer in the absence of Pif1p than in the presence of wild-type PIF1, indicating that endogenous Pif1p inhibits the active S/G2 form of telomerase. Pif1p abundance was cell cycle regulated, low in G1 and early S phase and peaking late in the cell cycle. Low Pif1p abundance in G1 phase was anaphase-promoting complex dependent. Thus, endogenous Pif1p is unlikely to act on G1 bound Est2p. Overexpression of Pif1p from a non-cell cycle-regulated promoter dramatically reduced viability in five strains with impaired end protection (cdc13-1, yku80Delta, yku70Delta, yku80-1, and yku80-4), all of which have longer single-strand G-tails than wild-type cells. This reduced viability was suppressed by deleting the EXO1 gene, which encodes a nuclease that acts at compromised telomeres, suggesting that the removal of telomerase by Pif1p exposed telomeres to further C-strand degradation. Consistent with this interpretation, depletion of Pif1p, which increases the amount of telomere-bound telomerase, suppressed the temperature sensitivity of yku70Delta and cdc13-1 cells. Furthermore, eliminating the pathway that recruits Est2p to telomeres in G1 phase in a cdc13-1 strain also reduced viability. These data suggest that wild-type levels of telomere-bound telomerase are critical for the viability of strains whose telomeres are already susceptible to degradation.
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Meguiar's Instant Car Care Clinic - Get a free car care prescription that is tailored to your vehicle, your local environment and your specific goals. Just tell us the current condition of your vehicle, what your appearance goals are for your vehicle, and where you live and you'll receive recommendations on exactly what to use and how often to use it. Besides paint care, the Meguiar's will also recommend products to make your car's glass sparkle, wheels and tires shine and even detail your engine. Instant Car Care Clinic makes it easy to care for every surface of your vehicle.
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Meguiar's Online Forum - Meguiar's Online Forum is an online community for people interested in learning more about detailing cars and the wide spectrum of Meguiar's car care products. The community is made up from professional detailers to first time car owners. Everyone is helpful and ready to answer your questions. Visit the forum and follow a wide variety of discussions about all kinds of detailing related topics. If you choose to become a member of the Meguiar's Online Forum, you'll receive your own Photo Gallery so you can display your car related photos.
Car Care FAQ's - When you want to find an answer to a car care question, look to Meguiar's Car Care FAQ's. You'll find answers to everyday questions like, "Which wax is the best for my car?" or "What's the difference between polishing and waxing?" A wealth of surface care knowledge has been collected here and it's available to you 24 hours a day, 365 days a year.
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Material Safety Data Sheets - Material Safety Data Sheets (MSDS) are provided here for our business customers to comply with OSHA regulations (link to MSD download page)


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Playing The Field | Blue Whisper (Indie) | The Gift (Indie) |
Final Witness (Pilot) | Eric, Rob, & Issac AD Guys |
Memorize lines quickly and can stay in character for long periods of time. Unique and expressive facial expressions. Loves to make people laugh and get a reaction. Great at sports – soccer, baseball skateboarding, scooter riding, bike riding, basketball, and ice skating. Quick study and takes direction very well. Great sense of humor and a very vivid imagination. Takes great pride in acting and works hard to get the character to be believable.
Fast Track Program (Invitation Only) - Cathryn Sullivan - C.Sullivan Studios, TX 2/08 – Present; On Camera, Stage & Improv Camp - Cathryn Hartt - Hart & Sole Studio, TX 7/11; Acting Seminar - LA Casting Agent - Lewisville, TX 5/11; Improv Skills Seminar - Michael Welch - Lewisville, TX 2/11; Commercial Technique Seminar - Casting Director - Dallas, TX 12/11; Many Workshops - Casting Directors - Dallas, TX 2/08 - Present;


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By taking the green rating into account when buying a new car, you can reduce your impact on the environment and save on your fuel costs.
The amount of carbon dioxide a car produces is directly linked to the type of fuel it uses and its fuel consumption. With fuel prices on the rise, a fuel-efficient model also means more money in your pocket: for every 10,000 km you drive, each L/100 km less fuel your car consumes than another model saves you $130 (based on a fuel price of $1.30).
The government's Green Vehicle Guide allows you to compare the environmental impact and fuel consumption of all new passenger and light commercial vehicles up to 3.5 tonnes. Each version of each model gets a star rating, with five stars being the best. The rating takes into account the car's emissions of greenhouse gases and other air pollutants. The website also tells you what type of fuel the car uses, and its fuel consumption. Our tables show you the ratings for the best (4.5–5 stars) and worst (one star) performers, as well as for the 20 best-selling models on the market.
Image source: TOYOTA
Receive FREE email updates of our latest tests, consumer news and CHOICE marketing promotions.
Full results for all models are shown in the table below.
1 Star rating This is based on the combined point scores of the greenhouse and air pollution ratings. For example, a five-star rating requires at least 16 points, 9.5–11.0 points score three stars, and a model with less than five points only one star.
2 Greenhouse rating This is based on the carbon dioxide (CO2) emissions measured during the standard test for the fuel consumption label. The amount of CO2 depends on the fuel consumption and the type of fuel. As an example of how the ratings relate to each other, a car with a score of 5 produces about twice as much CO2 as one scoring 8.
3 Air pollution rating As examples of how the scores relate to each other, a petrol or LPG model with a score of 8.5 emits only about a third of the amount of nitrogen oxides (NOx) and hydrocarbons (HC) of a car scoring 6.5, which in turn only emits half the amount or less of a 5-point model. The rating isn't based on actual emissions, but on the emissions of NOx and HC, as well as particulate matter for diesel vehicles, that are allowed under the emission standard to which the model is certified for the Australian market.
4 Fuel consumption This is the figure you'll find on the fuel consumption label each new car has to display on its windscreen. It's based on a mix of city and highway driving in controlled, standard laboratory conditions, so the results are comparable across car categories. However, real-life driving conditions, your driving style and the car's condition are likely to be different, and real-life fuel consumption is therefore usually higher than the label figure.
This table shows how top selling cars rate for green credentials


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Kiersten Van Houten
Last Modified: November 1, 2001
Copyright © 1995, Kiersten Van Houten
In my head In my mind, In the deepest part of me, A thought grows, And it gets bigger, Beginning to overload my head With an emotion, Sometimes sad. Sometimes happy, Sometimes neither one I think of My Father, who has cancer, Walking with a cane, Moving so slow, That thought always seems to be The biggest one to grow. The second
Jan 24, 2011 - Depression and anxiety may be less common in cancer patients than previously thought, but mood disorders still occur in a substantial number of patients in various hospital settings, according to research published online Jan. 19 in The Lancet Oncology.


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Lastminute.com brought us on board to build them a web-based app for their internal marketing team.
As a forefather of e-commerce, we were particularly keen to work with a client such as Lastminute.com.
With a specific brief and requirement, and some help from us, we were tasked with producing a tool to help automate their email marketing process. The outcome was a web-based email briefing machine. We are told it's been a great help to them and very definitely worth their while and the team are making use of the time saved by their new tool.


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Clinical Trials (PDQ®)
Basic Trial Information
Trial Description
Further Trial Information
Eligibility Criteria
Trial Contact Information
Phase | Type | Status | Age | Sponsor | Protocol IDs |
Phase III | Biomarker/Laboratory analysis, Treatment | Closed | 18 and over | NCI, Other | NSABP-P-5 NCI-2011-09183, NCT01011478 |
RATIONALE: Rosuvastatin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving rosuvastatin after surgery may kill any tumor cells that remain after surgery. It may also keep polyps from forming or colon cancer from coming back. It is not yet known whether rosuvastatin is more effective than a placebo in treating colon cancer that was removed by surgery.
PURPOSE: This randomized phase III trial is studying rosuvastatin to see how well it works compared with placebo in treating patients with stage I or stage II colon cancer that was removed by surgery.
Further Study Information
- To compare the effect of rosuvastatin vs placebo on the 5-year occurrence of adenomatous polyps of the colon or rectum, metachronous colorectal carcinoma, or colon cancer recurrence (APMC+R) in patients with resected stage I or II colon cancer.
- To determine whether the effect of rosuvastatin vs placebo is of the same magnitude in patients taking aspirin (regardless of dose) compared to patients not taking aspirin.
- To determine whether taking aspirin (regardless of dose) vs no aspirin will decrease the occurrence or APMC+R and, if there is an effect, to explore the relationship to dose.
- To determine the effect of rosuvastatin in patients with familial colorectal cancer.
- To determine the effect of rosuvastatin in patients with microsatellite unstable tumors (i.e., tumors displaying loss of MLH1 or MSH2 expression by IHC).
- To determine the relationship between rosuvastatin therapy and features of colorectal adenomas as well as the size and number of colorectal adenomas.
- To compare the time to APMC+R in patients treated with rosuvastatin vs placebo.
- To compare the disease-free survival of patients treated with rosuvastatin vs placebo.
- To compare the overall survival of patients treated with rosuvastatin vs placebo.
- To compare the rate of recurrence of colon cancer in patients treated with rosuvastatin vs placebo.
- To compare the rate of second non-colorectal primary cancers in patients treated with rosuvastatin vs placebo.
- To determine the effect of rosuvastatin on health-related quality of life, global quality of life, and self-reported symptoms.
- To compare the incidence and severity of adverse events associated with rosuvastatin vs placebo.
- To assess relevant tumor and blood markers that may affect the metabolism, activity, or effect of the study drugs, such as HMG-CoA reductase, UGT1A6, P450-2C9, PTGS2 (COX-2), and other possible markers.
OUTLINE: This is a multicenter study. Patients are stratified according to family history of a first-degree relative with colorectal cancer (yes vs no), intended aspirin dose (none vs 81 mg vs 325 mg), and adjuvant therapy for colon cancer (yes vs no). Patients are randomized to 1 of 2 treatment arms.
- Group 1: Patients receive oral placebo once daily for 5 years.
- Group 2: Patients receive oral rosuvastatin once daily for 5 years.
Patients may complete a quality-of-life questionnaire at baseline and at 6, 12, 36, 60, and 84 months.
Tumor tissue, serum, and blood samples may be collected periodically for biomarker and other analyses.
After completion of study treatment, patients are followed up periodically for up to 2 years.
Eligibility Criteria
Inclusion Criteria
- Patients must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
- Patients must have the ability to swallow oral medication.
- Patients must have resected adenocarcinoma of the colon staged as American Joint Committee on Cancer (AJCC) Stage 0, I, II, or III.
- Patients must have had surgical resection of the colon adenocarcinoma with curative intent within 1 year prior to randomization. (Laparoscopically-assisted colectomy is permitted.)
- Patients must have completed any adjuvant therapy prior to randomization.
- Patients who are taking cardioprotective low-dose aspirin at study entry must not have clinically significant toxicity, as determined by the investigator, that precludes continuation of aspirin, and the patient must be willing to continue aspirin therapy (81 mg or 325 mg) throughout study therapy.
- Colonoscopy requirements within 180 days prior to randomization:
- The patient must have either undergone a preoperative or postoperative documented colonoscopy to the cecum (or small bowel anastomosis) with adequate bowel preparation.
- All observed polyps must have been removed. (Polyps can be removed during colonoscopy or surgery performed prior to randomization.)
- Postoperative serum creatinine performed within 90 days prior to randomization must be less than or equal to 1.5 x upper limit of normal (ULN) for the lab.
- The following criteria for evidence of adequate hepatic function based on postoperative testing performed within 90 days prior to randomization must be met: aspartate aminotransferase (AST) or alanine aminotransferase (ALT) less than or equal to 3.0 x ULN for the lab, and Total bilirubin less than or equal to 1.5 x ULN for the lab
Exclusion Criteria
- Tumor with the distal border located less than 12 cm from the anal verge.
- Total colectomy or total proctocolectomy.
- Classic Familial Adenomatous Polyposis, Attenuated Familial Adenomatous Polyposis (i.e., 20 or more adenomas, either synchronous or metachronous), or Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome).
- Malabsorption syndrome, ulcerative colitis, inflammatory bowel disease, resection of the stomach or small bowel, or other disease significantly affecting gastrointestinal function.
- History of documented upper GI bleeding or upper GI ulcerative disease.
- Statin use within 30 days prior to randomization.
- Hyperlipidemia with clinical indication for statin therapy or other prescribed medication. Determination of acceptable fasting lipid values, within 90 days prior to randomization, should be in accordance with current dyslipidemia management guidelines.
- Unwillingness to discontinue chronic use of nonsteroidal antiinflammatory drugs (NSAIDs) (other than cardioprotective low-dose aspirin 81 mg or 325 mg) prior to randomization.
- Anticipated need for chronic use of NSAIDs (other than cardioprotective low-dose aspirin 81 mg or 325 mg).
- Inadequately treated hypothyroidism, as determined by the investigator.
- History of myopathy or rhabdomyolysis.
- Hypersensitivity or intolerance to statins.
- Chronic drug therapy with cyclosporine, coumarin anticoagulants, gemfibrozil, some other lipid-lowering therapies (fibrates or niacin), lopinavir/ritonavir, or drugs (such as ketoconazole, spironolactone, or cimetidine) that lower levels or activity of steroid hormones.
- Pregnancy or lactation at the time of study entry. (Pregnancy testing must be performed within 14 days prior to randomization according to institutional standards for women of childbearing potential.)
- Previous malignancies unless the patient has been disease-free for 5 or more years prior to randomization and is deemed by the physician to be at low risk for recurrence. Patients with the following cancers are eligible if diagnosed and treated within the past 5 years: all in situ cancers and basal cell and squamous cell carcinoma of the skin.
- Other non-malignant systemic disease that would preclude a patient from receiving rosuvastatin or would prevent prolonged follow-up.
- Administration of any investigational agent within 30 days before randomization.
Trial Lead Organizations/Sponsors
National Surgical Adjuvant Breast and Bowel Project
National Cancer InstituteNorman Wolmark | Principal Investigator |
Link to the current ClinicalTrials.gov record.
NLM Identifer NCT01011478
ClinicalTrials.gov processed this data on February 27, 2015
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Peak District green lanes get permanent vehicle bans
Two Peak District routes are to get permanent vehicle bans despite protests from campaigners.
Long Causeway and Roych will both be subject to full traffic orders when limited controls associated with repair work come to an end.
The park authority said the restrictions were needed to protect the wildlife and character of the trails, known as green lanes.
But a pro vehicle group said it would lead to a "sanitised" countryside.
Park officials have been looking to cut the use of motor vehicles on the green lanes - a series of unsurfaced routes - for several years but have faced repeated protests and even legal action.
Green lanes vehicle ban timeline
- November 2011: The authority agrees to spend £100,000 on a two-year campaign to protect so-called "green lanes"
- May 2012: The authority starts consulting on the process
- September 2012: Trail riders organise "go slow" protests on the park's main roads
- December 2012: A temporary order banning vehicles from Chapel Gate is overturned in the High Court
- May 2013: Authority starts another public consultation on closing the route
- July 2013: The nearby Roych green lane is closed following a consultation
- September 2013: Park authority confirms permanent restrictions on Long Causeway and Roych
Now permanent orders have been approved for the 2.2 mile (3.5km) Roych, part of the Pennine Bridleway, near Chapel-en-le-Frith and a similar length of Long Causeway near Stanage Edge.
Christopher Pennell, who chairs the committee which made the latest decision, said: "We have given careful consideration to a range of options including partial restrictions of vehicle access, but, these would not have safeguarded the area's exceptional natural beauty and internationally important wildlife and habitats.
"In view of the area's significant environmental sensitivity and to preserve opportunities for its quiet enjoyment, the committee decided the best option for Long Causeway is to stop vehicles from using it."
Both routes currently have restrictions imposed by Derbyshire County Council during repair work.
The park authority's traffic orders come into force when the work finishes but no date for this has been confirmed.
Officials also said all similar routes would be monitored and further restrictions would be considered if damage was detected.
Richard Simpson, from Trail Riders Fellowship, said: "We are not surprised, the committee had its mind made up on this from the off.
"The park authority is spending a lot of money to exclude people who bring important revenue.
"I can see this ending with everyone, including mountain bikers and horse riders, restricted to a few approved routes in a very sanitised version of the countryside."


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PeanutsTuesday, January 10, 2006
Nestle Crunch with PeanutsAs I reviewed last week, Nestle is creating some limited edition bars. This tactic seems to encompass adding peanuts to current candy bars. The Nestle Crunch with Peanuts is simply a Nestle Crunch bar with peanuts mixed in. Think of it as Mr. Goodbar meets Krackel (well, if you were in the Hershey's universe). It's a really nice bar and I like how the peanuts moderate the sweetness of the Nestle chocolate. I actually prefer it over the regular Crunch bar which I've always found a little too sweet and bland. The crunches come from both the crisped rice and the roasted peanuts - so there's variation in texture and taste. I certainly prefer it to the Crunch with Caramel they did a while back. It also seems to be more innovative than the White Chocolate and Dark Chocolate versions from last year. I'm not likely to buy these, but if there were an assortment of Nestle miniatures with them in it, they'd certainly be one of the first I'd pick out. The other thing I like about adding nuts to chocolate and other sweets is that it gives a little protein/fat punch to the sugar. I know it sounds odd to be talking about things like glycemic load when talking about candy, but I like to feel good while eating candy and an hour later, instead of having a severe sugar crash and getting the shakes.
Friday, January 6, 2006
Take 5 Peanut ButterThis candy bar irritated me from the moment I picked it up. First was the rich mustard color of the wrapper. A compelling "look at me!" color, but not one that makes me think of peanuts in a fond way. (In fact, it makes me think of a peanut butter and mustard sandwich, which probably has some fans out there, but I can't count myself as one of them.) The second thing that rubbed me that wrong way when I read the package was the description, "pretzels, caramel, peanuts, peanut butter & peanut butter candy." What the heck is "peanut butter candy" and how is that different than the whole thing being considered a "peanut butter candy?" What I thought the peanut butter candy part meant was something like the inside of a Butterfinger bar (or a 5th Avenue if we're sticking to Hershey's products). And that actually sounds kind of interesting, have a layer of peanut crisp in there somewhere. What I didn't realize is that this bar has no chocolate (poor reading comprehension on my part) ... and that's what the peanut butter candy replaces. It's basically a peanut butter-white chocolate. Like the insides of Reese's Pieces! Of course this means partially hydrogenated oils. Bah! I don't want partially hydrogenated oils in my candy! Anyway, you get two bars in each package (which has a nice cardboard tray to keep them from getting crushed). The outside is a little odd looking as you can see the grains of peanut butter, but I got over that. It smells peanutty and is smooth, crunchy and has a nice hit of salt in it. I got no sense of the caramel at all. There was no chewiness to this bar at all, in the caramel sense. I suspect that the fats from the various peanut incarnations invaded the caramel and de-chewified it. If you're a big peanut fan and are not satisfied with the bazillion other Reese's branded bars, you can pick this up and argue with me about the glory that is a Peanut Butter Take 5. Instead of mucking around with adding more peanuts to the Take 5 line, they need to start making my version with extra dark chocolate and pecans! Interesting things: Take 5 bars are called Max 5 in Canada. The peanut butter version of the bar contains 2 more grams of saturated fat over the regular chocolate one, but twice the fiber. This is not a limited edition bar. Other Take 5 versions: Take 5 Chocolate (9/10) & White Chocolate Take 5 (6/10).
Tuesday, January 3, 2006
100 Grand with PeanutsIt looks like Nestle is finally going to go whole hog into the Limited Edition stuff like Hershey's and Mars have been doing. I saw a few mentions on Junk Food Blog about new Nestle Limited Edition candies. I immediately ran out to my local 7-11 that seems to carry these things and was lucky enough to find it on my first try. The 100 Grand with Peanuts is exactly what you'd think. A 100 Grand bar, which is caramel covered in milk chocolate and crisped rice. In this case the peanuts are mixed in with the caramel, not with the milk chocolate. First of all, during the five year period of time when I faithfully adhered to the Nestle boycott, the one bar that I missed was the $100,000 Bar (as it was called at the time). There is no other bar like it; caramel, chocolate and crisps seems like an obvious combination, but Nestle seems to have "unique" as a selling point. (Yes, Steve Almond goes on about some bar called a Caravelle in Candy Freak which was similar but better, but I don't think I ever had one.) This new version is interesting. Even though there aren't a lot of peanuts, because they're whole and mixed in with the caramel, it really bursts with caramel flavor, but not a lot of actual caramel chew. The salty-ness of the caramel goes nicely with the peanuts but I'm not getting enough sticky caramel to give me the nice contrast with the crispy rice. But, I'm comparing it to the regular 100 Grand. I think a better thing to compare it to is the Snickers Cruncher bar, which it seems I liked much better. Snickers just knows the peanut/chocolate combo much better. I'll keep picking up the regular 100 Grand in the future. Unless they bring back the Caravelle, then you can expect a new review.
Friday, December 30, 2005
Short & Sweet: Butterfinger Jingles and Mint MiniaturesThe Man picked up some new stuff for the stockings this year. Besides the typical hard candies (Brach's) and Hershey's Kisses (in red and green foils) we got two new items: Butterfinger Jingles (Nestle) - you know what's great about these? They're made with real milk chocolate. Instead of that waxy "chocolate coating" on the Butterfinger bar, Jingles start with real milk chocolate and then put little crunches of Butterfinger centers. They're a bit bigger than a Hershey's Kiss, which is a little too big in my opinion, but I'll survive with a larger bite. The other thing is, these made me realize is how clever Milton Hershey was when he decided how to wrap the Kisses with the foil wrapping "up" the Kiss, instead of putting the edges of the foil on the bottom. This is evident with the Jingles because all the foil edges are folded to the bottom of the Jingle so that it doesn't have a flat bottom ... they wouldn't sit straight for my photo. The other new candy for us was the Hershey's Mint Mix Miniatures. There are three different bars, Milk Chocolate with Mint, Semisweet Chocolate with Mint and White Chocolate with Mint and Candy Bits. The Milk Chocolate with Mint is positively blasted with mint. Seriously minty. Not Altoid-level, but for a chocolate product, I'm surprised it was brown it was so minty. I had to sequester these bars from the rest of the stocking mix because they were contaminating the Jingles. No one wants minted Butterfinger Jingles. The dark one was nice, nothing to write home about and maybe a little sweet but I did actually enjoy the White Chocolate one. I know, white chocolate, most people go, "ew." But I do have a fondness for misty mints and let's face it, that's all this is. The good news is that Hershey's uses actual cocoa butter in their white chocolate, so at least it's not jam-packed with trans fats. They are actually the best thing in this mix, smooth, not too sweet and not too artificially vanilla tasting. If you see any of these on sale after Christmas, they're well worth picking up to keep around for snacking. I really don't care what my candy is dressed in, as long as it's good. Rating - 7 out of 10 (but if you can find them for 75% off, then it's a 10 all the way) POSTED BY Cybele AT 4:27 pm Candy • Review • Christmas • Hershey's • Nestle • Chocolate • Mints • Peanuts • White Chocolate • 7-Worth It • United States • Wednesday, December 7, 2005
Clark BarName: Clark Bar I finally tracked down a Clark bar (they aren't that easy to find on the West Coast). Clark bars were originally manufactured by the Clark company in Pittsburgh, Pennsylvania starting in 1917 (WWI) but were bought a few years back by Necco. I remember when I lived in Pittsburgh one of the best things about it was the huge, lit Clark sign on the factory. What I also liked about the Clark company is that they made one of my favorite gums, Teaberry. The Clark bar is very similar to the Butterfinger and the current 5th Avenue bar. (All of these bars have changed hands over the years, Butterfinger was originally made by Curtis and 5th Avenue was by Ludens.) It's possible Clark was the original peanut butter honeycomb bar, but even if it wasn't it was one of the few to survive to the present day. The center of a Clark bar is honeycomb peanut butter crisp covered in a chocolate-like substance (I don't know if it was ever covered in real chocolate). Given the choice when it came to peanut crisp bars, I usually opted for the Zagnut, which is a coconut covered peanut crisp bar (now made by Hershey's). So my recollection of the real Clark bars is a bit dim. But what I can tell you about the one I tried is that it's very dense. It's not crispy like a Butterfinger and it lacks the complex toasted flavors of the 5th Avenue. (Look at the photos on the head to head review to see the difference in the centers.) However, the fake chocolate is much better than most, it's sweet and smooth without being waxy. The crisp ends up becoming rather chewy and finally gives up a little more molasses flavor, but still doesn't have the pop that 5th Avenue gives me. (Related nostalgia - Clark wrappers, Clark bar memories, Clark sign on Flickr, two more shots of the same old sign, story about classic sign on North Side.) Rating - 5 out of 10 UPDATE April 21, 2010: Necco has updated the Clark Bar, it's now bigger and has a real chocolate coating. They're also available in dark chocolate. Check out the new reviews as well as a full head-to-head comparison of Butterfinger, 5th Avenue and Clark Bar. Related Candies
POSTED BY Cybele AT 9:03 am Candy • Review • Necco • Chocolate • Mockolate • Peanuts • 5-Pleasant • United States • Comments (71) Monday, December 5, 2005
Reese's Snack BarzName: Reese's Snack Barz You know this is a cool candy for kidz because there's that hip Z at the end. This bar is not really a snack bar in the sense that a power bar or some sort of trail mix bar would be. It's a candy bar. (I think most bar shaped things that are sweet are considered candy bars whether you stuff some vitamins in there or not.) This bar is a peanut butter marshmallow crisped rice treat with a base of chocolate. The peanut butter mixed in with the marshmallow cement is smooth and nutty with a good hit of salt. The crisped rice is, well, crispy and it all pulls apart easily without crumbling into bits (as is a problem with some crunchy granola bars). The chocolate base for the whole thing is a really nice sweet complement. Hershey has a full range of these bars in different flavors including S'mores and Chocolate Cream. They're apparently fortified with calcium and seven essential vitamins (only 15% of the RDA for them though) and have no saturated fats but 3 grams of protein. There are worse decisions you can make for snack foods and certainly better ones in the candy family, but this is a nice in-between food. It's certainly satisfying and is a rather large feeling bar. I can see this being a good candy to travel with, a nice little snack on the plane with a watery cup of coffee to wash it down. Rating - 8 out of 10 Monday, November 21, 2005
Best Intentions: Sun DropsName: Sun Drops - Plain Milk & Peanut Here's a perfectly good idea gone awry. There's no reason there can't be good, tasty, "natural" chocolate candies (I think that's been proven more recently with things like Equal Exchange, Green & Black, Newman's Own, etc.). This is an example of a weak candy line. Here's why: First, the colors are dull and unappealing. They're not colors that I want to eat (except for the yellow, they look like old-lady lipstick colors). They're not strong or clean, they're muddy looking and uneven. A grainy looking outside does not bode well for the inside. The ingredients are basically sugar (natural with unsulfured molasses, blah, blah) then milk powder, then the chocolate ... that's a long way down the list. And it shows in the final product. The addition of molasses is a little odd. It gives the whole thing a rather toasty burnt flavor, which I enjoy with my oatmeal but not in my chocolate. In fact, I can taste everything in these drops except for the chocolate. The powdered milk, overly sweet sugar and slightly grainy chocolate just combine for a depressing treat. The crunchy shell is too tough and again adds sweet without flavor and further distances me from any chocolately goodness. If it's possible, the peanut ones tasted more like burnt sugar and milk powder. With the same number of calories and fat as M&Ms, why am I eating these? I gave them to Amy to try and after much cajoling (because the package, colors and list of ingredients scared her off - and she was the one that wanted to go to Wild Oats on Saturday!) she did put one in her mouth. She chewed a couple of times and then spit it out in my trash can. If you are a parent trying to find a wholesome treat for the kids, this isn't it. It sets them up for a lifetime of disappointments, now that's spoiling them. Just let them have some M&Ms in moderation (the Almond ones are actually not bad for you since the bulk of the candy is actually a very healthy nut). Or just let them have plain old semi-sweet chocolate chips. Dark chocolate really isn't that bad as a food. Raisinettes? Really, anything but this. Don't tease the poor kids by telling them this is candy. Rating: 2 out of 10 POSTED BY Cybele AT 9:39 am Candy • Review • Sunspire • Chocolate • Peanuts • 2-Appalling • United States • Comments (42) Wednesday, November 16, 2005
NutrageousName: Nutrageous Again I'm trying another Reese's candy bar. I'm not sure why. I think Reese's cups are pretty darn close to candy perfection. The Nutrageous bar adds whole nuts and caramel to that. The bar, as the photo shows, is a center of peanut butter (which is more crumbly than creamy), which has a caramel stripe under it, then the whole thing is rolled in nuts and covered in milk chocolate. It's a really satisfying, meaty bar. Not too sweet, a good hint of salt to it and some good textures. I don't know why I haven't tried this bar sooner. I prefer it far and away over a Snickers bar, which is a little too sticky sweet for me. It's still not a "go to" bar for me. I'll still pick up a packet of Reese's cups before this, unless I was really looking for a calorie charge with more protein in it. (Reese's cups has 4 grams of protein, the Nutrageous has 6 grams.) Rating - 7 out of 10 POSTED BY Cybele AT 9:12 am Review • Hershey's • Caramel • Chocolate • Peanuts • 7-Worth It • United States • Comments (18) |
Meticulously photographed and documented reviews of candy from around the world. And the occasional other sweet adventures. Open your mouth, expand your mind.


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Wounds of Waziristan Trailer
Wounds of Waziristan Trailer
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Alum AJ Russo (BA '88-'89) is working on "Wounds of Waziristan" with director is Madiha Tahir, an indie journalist based out of NYC and raised between Pakistan and NJ.
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It's been an uneven freshman year for new sitcom The Mindy Project. After a rocky start we've seen a few characters come and go, a string of Mindy Kaling's boyfriends get the axe, a bunch of truly memorable episodes (like Seth Rogen's visit or the company triathlon), and, of course, one haircut so awful it could have been made with a Flowbee. When the finale aired last night, I was so happy that there was another high point not only of Fox's Tuesday night lady-comedy block, but of the week in general. That is until the last few minutes of the episode where I was more disappointed than Mindy finding out there are no peanut M&Ms in the vending machine.
I was pissed because it looked like Mindy and Danny were going to smooch. By the last scene, Mindy had won her man Casey back and planned to move to Haiti with him for a year. But then she had a touching moment in the doctor's lounge with her coworker and foil Danny (the impossibly dreamy Chris Messina) and he leaned in toward her for what looked like I kiss and I shouted out, "No!" at the television screen. They didn't kiss, but they had one of those conversations in soft tones that is supposed to make the audience think, "Maybe she should leave her boyfriend, the one who is impossibly handsome, giving, kind, funny, wonderful, and has a big penis, so that she can be with Dr. Danny."
Let's get this clear, writers and producers of The Mindy Project...No one wants Mindy and Danny to get together. Not one single person who watches this show regularly wants this to happen. None! This seemed like the intention as the show kicked off, but like so many things this year, it seemed to course correct in a different direction. They went from Sam and Diane on Cheers, adversaries whose chemistry crackled with sexual tension, to Jack and Liz on 30 Rock, friends who approached the world from different angles but learned from each other. They've grown so close in a Platonic way that when they went for what seemed like it might be a kiss it seemed like Danny was about to kiss his younger sister or was going to lay one on a baby goat, something that would make us squirm or maybe giggle, but nothing that was going to make the live studio audience let out a collective "Awwww."
Not every man and woman on a show need to get together. Sure, New Girl has fast-tracked the Jess and Nick romance so that they're sweetly bumping uglies at the end of Season 2, but The Mindy Project is not New Girl. Unlike its predecessor in the lineup, it is essentially a workplace comedy (which is why they ditched the dead weight of having Mindy's friends in the episodes) and people hooking up with their coworkers never ends well in real life and ends even worse on TV. So give it a rest with the Mindy and Danny hot and heavy action, will you? With all the improvements made this year, Season 2 is shaping up to be humdinger, as long as they don't mess it up with Mindy and Danny humming and dinging for each other.
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