text:
Comparison of the Pharmacokinetics and Pharmacodynamics of the Aldose Reductase Inhibitors, AL03152 (RS), AL03802 (R), and AL03803 (S)
- Young Han Park,
- Philip R. Mayer,
- Ronnie Barker,
- Mark DuPriest,
- Brenda W. Griffin,
- Gary W. Williams,
- Billie M. York,
- John T. Slattery
- … show all 8 hide
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The pharmacokinetics of AL03152 (RS) and its enantiomers, AL03802 (R) and AL03803 (S), were studied in the Sprague–Dawley rat following intravenous bolus administration. The enantiomers had differing pharmacokinetic profiles, while the racemic compound exhibited pharmacokinetic parameters approximating the mean values of the individual enantiomers. The total clearance (CLT) values of the two enantiomers were similar, but the intrinsic clearance (Clint) was much greater for the S-enantiomer than for the R-enantiomer. The volume of distribution (Vss) for AL03802 (R) was threefold greater than that for AL03803 (S). The stereoselectivity in V ss could not be totally accounted for by the slight difference in serum protein binding of the isomers and resulted in a difference in the half-lives of the enantiomers. Only the R-isomer exhibited a persistent terminal elimination phase, consistent with more extensive tissue binding than the S-isomer. AL03152 enantiomers were equivalent in potency assessed from in vitro IC50 values toward rat lens aldose reductase and rat kidney L-hexonate dehydrogenase and lens EC50 values in diabetic rats.
- R. K. Brazzell, Y. H. Park, C. B. Wooldridge, B. McCue, R. Barker, R. Couch, and B. York. Interspecies comparison of the pharmacokinetics of aldose reductase inhibitors. Drug Metab. Disp. 18:435–440 (1990).
- R. K. Brazzell, P. R. Mayer, R. Dobbs, P. J. McNamara, R. Teng, and J. T. Slattery. Dose-dependent pharmacokinetics of the aldose reductase inhibitor imirestat in man. Pharm. Res. 8:112–118 (1991).
- Y. H. Park, R. Barker, B. Griffin, D. Barratt, M. DuPriest, K. Brazzell, B. York, and P. Mayer. Pharmacokinetics and efficacy of structurally related spirohydantoin and spirosuccinimide aldose reductase inhibitors. Xenobiotica 22:543–550 (1992).
- Y. H. Park, P. Mayer, K. Brazzell, B. York, R. Barker, B. McCue, J. Mattern, B. Bracken, M. Stoltz, and R. Couch. Comparative disposition studies of the aldose reductase inhibitors imirestat and AL03152. Abstracts, Third North American ISSX Meeting, 1990, p. 18, No. 41.
- B. W. Griffin, G. W. Williams, J. Y. Crider, R. K. Brazzell, P. R. Mayer, Y. H. Park, M. T. DuPriest, and B. M. York. Efficacy of aldose reductase inhibitors AL03152 and AL04114 administered to diabetic rats for one month. Abstracts, United States-Japan Aldose Reductase Workshop, 1991, p. 89, P38.
- P. J. McNamara, R. A. Blouin, and R. K. Brazzell. Serum protein binding of AL01576, a new aldose reductase inhibitor. Pharm. Res. 5:319–321 (1988).
- B. A. McCue, Y. H. Park, R. K. Brazzell, and J. J. Boltralik. Capillary gas chromatographic—electron-capture assay for the aldose reductase inhibitor imirestat in lens and plasma. J. Chromatogr. 565:255–264 (1991).
- B. W. Griffin and L. G. McNatt. Characterization of the reduction of 3-acetylpyridine adenine dinucleotide phosphate by benzyl alcohol catalyzed by aldose reductase. Arch. Biochem. Biophys. 246:75–81 (1986).
- B. W. Griffin, L. G. McNatt, M. L. Chandler, and B. M. York. Effects of two new aldose reductase inhibitors, AL01567 and AL01576, in diabetic rats. Metabolism 36:486–490 (1987). CrossRef
- K. Yamaoka, T. Nakagawa, and T. Uno. Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations. J. Pharmacokin. Biopharm. 6:165–175 (1978).
- Y. H. Park, C. B. Wooldridge, J. Mattern, M. L. Stoltz, and R. K. Brazzell. Disposition of the aldose reductase inhibitor AL01576 in rats. J. Pharm. Sci. 77:110–115 (1988).
- J. Y. Chien, C. R. Banfield, R. K. Brazzell, P. R. Mayer, and J. T. Slattery. Saturable tissue binding and imirestat pharmacokinetics in rats. Pharm. Res. 9:469–473 (1992).
- Y. H. Park, P. R. Mayer, R. Barker, J. Mattern, B. Griffin, G. W. Williams, and B. M. York. Comparison of the pharmacokinetics and efficacy of the aldose reductase inhibitors, AL03152 (RS), AL03802 (R) and AL03803 (S). Gordon Research Conference on Drug Metabolism, 1991, Poster No. T-8.
- Personal communication with D. Ziegler of Clayton Foundation Biochemical Institute and Department of Chemistry and Biochemistry, University of Texas, Austin, TX 78712.
- Title
- Comparison of the Pharmacokinetics and Pharmacodynamics of the Aldose Reductase Inhibitors, AL03152 (RS), AL03802 (R), and AL03803 (S)
- Journal
Pharmaceutical Research
Volume 10, Issue 4 , pp 593-597
- Cover Date
- 1993-04-01
- Print ISSN
- 0724-8741
- Online ISSN
- Publisher
- Kluwer Academic Publishers-Plenum Publishers
- Additional Links
- Topics
- Keywords
- aldose reductase inhibitor
- enantiomers
- pharmacokinetics
- Industry Sectors
- Authors
- Young Han Park (1)
- Philip R. Mayer (1)
- Ronnie Barker (1)
- Mark DuPriest (1)
- Brenda W. Griffin (1)
- Gary W. Williams (1)
- Billie M. York (1)
- John T. Slattery (2)
- Author Affiliations
- 1. Research and Development, Alcon Laboratories, Inc., 6201 South Freeway, Fort Worth, Texas, 76134
- 2. Department of Pharmaceutics, University of Washington, Seattle, Washington


text:
SSR 2013 does not restore folder contents
Article:TECH200578 | | | Created: 2012-12-06 | | | Updated: 2013-09-24 | | | Article URL http://www.symantec.com/docs/TECH200578 |
NOTE: If you are experiencing this particular known issue, we recommend that you Subscribe to receive email notification each time this article is updated. Subscribers will be the first to learn about any releases, status changes, workarounds or decisions made. |
When you restore a folder from a file folder backup, the contents of the folder are not restored.
This is a known issue that will be fixed in the future releases or service packs.
Rather than restoring on folder level, restore the contents (files) of the folder individually.
Symantec Corporation has acknowledged that the above-mentioned issue is present in the current version(s) of the product(s) mentioned at the end of this article. Symantec Corporation is committed to product quality and satisfied customers.
This issue is currently under investigation by Symantec Corporation. Pending the outcome of the investigation, this issue may be resolved by way of a patch or hotfix in current or future revisions of the software. However, this particular issue is not currently scheduled for any release. If you feel this issue has a direct business impact for you and your continued use of the product, please contact your Symantec Sales representative or the Symantec Sales group to discuss these concerns. For information on how to contact Symantec Sales, please see http://www.symantec.com
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Description | Restore of Folder from File/Folder backup does not restore contents of the folder |
Article URL http://www.symantec.com/docs/TECH200578
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subset: commoncrawl


text:
You hear this saying all the time, "Preach the gospel…if necessary use words."
You don't have to have the Bible memorized to make a difference in people's lives…it's really just about being a friend.
I'm reading this new book, by Bob Goff it's called Love Does. Full of stories from his life…about acts of love…not telling people that their life is wrong and dragging them to church…(I'm sorry if someone has done that to you). He writes about doing things out of love for others…
I highlighted this passage:
"I'm not that great at spelling and thankfully my phone auto corrects the words I type for me. What I've noticed though is every time I type in the word love, it gets changed to the word "live". It's a reminder to me of something I learned about following Jesus. I learned that fully loving and fully living are not only synonymous, but the kind of life that Jesus invited us to be part of. "
Love Does by Bob Goff
Now Playing: On Fire Artist: Sanctus Real On-Air: Larry & Lauren


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Build Desktop Apps with Sencha GXT
Title | Version | Date Added | Difficulty | |
Sencha GXT 2.x to 3.0 Migration Guide Sencha GXT 3.0 is the next generation of the components and tools that, in conjunction with the GWT compiler and runtime, make it possible to build large scale maintainable browser-based web applications. | 2.x, 3.x | Apr 30, 2012 | Easy | |
Running Ext GWT 2 and 3 Together Over the past weeks, we introduced you to some of the new features and improvements in Ext GWT 3. To allow a smooth transition from Ext GWT 2 to 3, Ext GWT lets you include both v2 and v3 components in the same application. This article explains the steps you need to take to run components from both versions at the same time. | 2.x, 3.x | Nov 29, 2011 | Easy | |
Ext GWT 3 Declarative Markup with UiBinder UiBinder support has been one of the major driving factors for many of the API changes in Ext GWT 3.0. | 3.x | Sep 19, 2011 | Medium |


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It's Halloween costume time again, and this time I need a costume for a puppy. I wanted to make something easy for Dexter to wear, since he has zero patience for nonsense right now.
I fell in love with this costume and it seemed easy enough to make. I made my costume for under $5 and it took me a little over an hour to complete. I had most of the necessary materials at home, I bought the harness at the dollar store and the Beanie Baby at a thrift store.
Tools and Supplies
You will need; a dog harness, a soft toy that has posable arms & legs (and a hat if possible), red & brown felt, shiny red fabric, black & white Vet Wrap (self-adhesive animal bandage), a china marker, a magic marker, scissors, needle & thread, a measuring tape and a hot glue gun.
STEP 1 – Fitting The Harness
Put the harness on your dog. Take the china marker and make marks approximately half way on your dogs shoulder.
STEP 2 – Making The Saddle Pad
Lay the harness flat and measure the length and width between the marks. You want a little overlap over the back strap of the harness, so add an inch or two. Use the marker to trace out the dimensions. Cut out the saddle pad piece with scissors.
STEP 3 – Making The Saddle
Fold the brown felt in half and trace out a size appropriate saddle shape. You might have to trim your shape down a few times until it fits on the saddle pad.
STEP 4 – Assembling The Saddle & Pad
Place the saddle shape onto the pad. Use the magic marker to make a few marks, under the saddle, to use as a guide for hot glue placement. Use the hot glue to trace the marked area. Put the saddle shape onto the hot glue and press firmly. Behind the saddle shape, use the magic marker to write a number.
STEP 5 – Attaching the Saddle & Pad To The Harness
To attach the saddle & pad to the harness, place generous strips of hot glue along the straps of the harness. Now the first part of the costume is finished!
STEP 6 – Preparing The Doll
Cut all clothing and accessories off of the doll.
STEP 7 – Making the Pants
Cut the white Vet Wrap into small strips. Half way up the legs of the doll, wrap the vet wrap around the legs. This is a totally lazy way of making pants for the doll since Vet Wrap sticks to itself. If you want to sew pants for the doll, go ahead!
Wrap the Vet Wrap around the midsection of the doll until no fabric is showing. The doll now looks like he is wearing riding pants!!
STEP 8 – Making The Boots
Cut small strips of the black Vet Wrap and wrap around the lower leg of the doll. Make sure that the black wrap lays over the white wrap to give a finished appearance.
Take the magic marker and colour in the shoes to give the appearance of the doll having tall riding boots.
STEP 9 – Making The Shirt
Take a rectangle of the shiny fabric, fold it in half and cut a semi-circle in the middle of the fold. Place the doll's head through the hole.
Locate the armpit of the doll. Cut the front of the fabric, stopping about 1/2″ below the doll's arm.
Flip the doll over. Hot glue the strip of fabric to the doll's arm and trim the excess.
Turn the doll back over. Cut the fabric from the back of the shirt about 1/2″ below the underside of the arm. Hot glue the fabric to the arm and trim excess fabric. Repeat for the other arm.
Fold the back sides of fabric to the front of the doll and hot glue down. Trim any excess fabric.
STEP 10 – Finishing The Doll
With the magic marker, colour the hat black & you're done! Using the needle and thread, sew the hat to the doll's head.
STEP 11 – Fitting the Doll To The Harness
Center the saddle pad between the legs of the doll and arrange the legs the way that you would like. Using the needle & thread, stitch the doll's legs to the saddle pad.


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Philips 700 PLUS Series brand longer lasting Warm White 32 Watt T8 fluorescent lamp with 700 Series color rendering. ALTO II technology uses less mercury for an environmentally safer lamp.
Full 32 Watts of light output
3000K Warm White color is popular with Hospitality businesses such as hotels and restaurants looking to achieve an inviting, relaxed atmosphere
700 Series Color Rendering Index means objects are less vibrant than those lit by 800 Series or 900 Series lamps with CRI in the 80's and 90's providing a better representation of true colors
Performance - well known brand name product at competitive price
Full case (25) only, priced per bulb
That's why we make the process as easy as possible and pledge to never leave you in the dark when it comes to buying replacement bulbs and lighting accessories.
Receive special offers and information from Bulbs.com.


text:
Wade H. Jeffrey
Current and Recent Research Projects
(click on the title for a project description)
Glacial "hitchhiking:" A mechanism for bacterial speciation in an extremely cold environment.
UV effects on marine production by bacteria and phytoplankton: Assessing the impact of UVB
Latitudinal effects of ultraviolet radiation on marine microbial communities and molecular diversity of genes important in biogeochemical cycles
Ultraviolet radiation induced DNA damage in bacterioplankton in
the southern ocean. II
Photochemical & trophic interactions and seasonal patterns of UV response.
Investigation of molecular diversity of important functional genes in marine bacteria
Ultraviolet radiation induced DNA damage in coral reef microbial communities
Science Training in Ecology Program
Oceanographic Techniques
Interactive Effects of UV and Vertical Mixing on Phytoplankton and Bacterial Productivity of Ross Sea Phaeocystis Blooms.
Interactive Effects of UV Radiation and Temperature on Pelagic Foodwebs
Back to Wade Jeffrey's Home Page


text:
Check Out the Companies with the...
Making Molecular Analysis Count in Diagnostics,...
Findings from the National Faculty Study
A Fast-Moving and Evolving Space
What does a retired chemistry professor do with his free time? Work on his online chemistry textbook, of course! That is precisely what Dr. Stephen Lower, formerly of Canada's Simon Fraser University, provides with his Chem1 Virtual Textbook. A project that began in the late 1980s, the online textbook includes 20 chapters that canvas the content of a year-long general chemistry course. The content pages include text and illustrations/diagrams, as well as a number of in-text links to other online resources. In addition to the text, the site includes a page of links for students, a page of links for teachers, and links to two other online chemistry texts. The entirety of the virtual textbook can be downloaded, and a section of the website highlights recent changes to the text.
*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.
Should bans on science education, of the sort imposed on Iranians hoping to study physics and engineering in the United States, encompass other nationals and other fields of study, including biotechnology?
Be sure to add email@example.com to your Address Book or Safe Senders List.
Click here for instructions.
If you have any questions about your subscription, click here to email us or call at (914) 740-2189.
You may also be interested in subscribing to the GEN magazine, an indispensable resource for everyone involved in the business of translating discoveries at the bench into solutions that fight disease and improve health, agriculture, and the environment. Subscribe today to see why over 60,000 biotech professionals read GEN to keep current in the areas of genomics, proteomics, drug discovery, biomarker discovery, bioprocessing, molecular diagnostics, collaborations, biotech business trends, and more.
© 2015 Genetic Engineering & Biotechnology News All Rights Reserved


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I would be remissed if I didn't remind everyone that it is Child Passenger Safety Week. Recently, I learned a little more about car seats thanks to the beautiful people at Britax. For example, I had my daughter's harness coming up and over her shoulders when in fact, they should have been coming down on her shoulders. As she's grown, I've adjusted some things but didn't realize the importance of others. Little things like that, that I never realized.
It makes me think about the very first time I put the frog princess in the car seat and I strapped the bottom of the harness wrong. I cannot tell you how many books I read, how much I checked safety, researched what I had in the home, took childbirth classes, etc. But here I was having never really taken the time to figure out how a car seat was supposed to work.
Something as simple as the fact that when you latch them up top you need to move that up to their chest area as opposed to leaving it around their bellies in case of accidents. I could go on and on and on.
According to the US Department of Transportation's National Highway Traffic Safety Administration (NHTSA), the majority of car seats are still not used correctly. Up until recently, I was part of that group. The idea that car crashes are the leading cause of death in children 1-13 was sobering to read.
This isn't a post where I'm going to tell you what you should buy. This is a post where I share my open and honest opinions (like you didn't already know this). Because of all of the times for you to not be sure about something, this would rank way a the bottom.
Last week upgraded my baby girl to what I like to call the ultimate booster seat. I now have the peace of mind of knowing not only that I have the best protection out there for her but, that I'm using the car seat the way that it was intended.
On September 22, 2012 car seat inspection stations nationwide will provide car seat checks and hands-on advice to parents and caregivers about selecting the right car seat for a child's age and size as well as installation tips. I think I'll swing by one and make sure I have everything in order, just in case I missed something. How about you?
Here are some additional resources for you:
- Tips for safely installing car and booster seats.
- A car seat inspection station locator that includes the option of searching for Spanish-speaking technicians.
- Instructional videos for installing several types of car seats and booster seats.
- An ease-of-use rating system for car seats and booster seats.
Stay safe!


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Communities begin approving CILA homes
by WILY/WRXX News Staff • April 15, 2013 • News
As one community fights against the closure of the Warren G. Murray Center in Centralia, another community has announced the opening of a new group home for individuals with developmental disabilities will open in their community this spring.
The West Frankfort City Council has agreed to donate three lots to the H Group for a "community integrated living arrangement."
The home will bring at least nine full- or part-time jobs with it, according to Rob Ford, the h group director of vocational and residential services.
The h group hopes to open the home by june 1.


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Episode Information
This week on The Needle Drop, the UK post-punk trio Let's Wrestle makes their US debut with a new album. In the Court of the Wrestling Let's is an assembly of new tracks and rerecorded favorites from past releases. Like their name suggests, Let's Wrestle comes across pretty rowdy, but their hooks are extremely calculated and well-written. Some attitude, some swagger, some sophomoric charm: What's not to like?
We've got new tracks from the National and Tobacco; plus, Titus Andronicus' new album The Monitor. Titus takes the sweaty, feral, punk-fueled sounds of their first album, but applies them to the most unlikely album concept: the American Civil War.
- Let's Wrestle- I Won't Lie To You
- Let's Wrestle- Tanks
- Let's Wrestle- Insects
- Pete & The Pirates- Jennifer
- Let's Wrestle- We Are The Men You'll Grow To Love Soon
- The National- Bloodbuzz Ohio
- Tobacco- Sweatmother
- Jamaica- I Think I Like U 2
- The Tallest Man On Earth- Burden of Tomorrow
- Autechre- Qplay
- Titus Andronicus- A More Perfect Union
- Titus Andronicus- ...And Ever
- Titus Andronicus- To Old Friends and New


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Cycle Toronto Observes More Bikes than Cars on College Street
Submitted by Jared Kolb on 13 December, 2013 - 09:38
Torontonians are commuting by bicycle more now than ever, and in record numbers.
Cycle Toronto observed this trend this fall, when it counted more bikes than cars on College St. On Thurs Sept 19th, from 5pm to 6pm, Cycle Toronto counted 680 bikes and 618 cars travelling westbound. The overall bicycle mode share was 52%, and one 15-minute interval had a mode share of 57%. This hourly count occurred within an overall westbound count between 4:30pm and 6:30pm of 1,150 bikes and 1,227 cars (48% bikes, 52% cars). Since 2010, bike traffic on College St has increased by 67%!
Illustration by Mike Himmel. Bicycle counts completed by John Taranu, Burns Wattie and Antony Hilliard. Special thanks to the University of Toronto Cycling Think and do Tank for enabling the counts. Our counts are available here and the raw video here . Download & share the graphic file attached at the bottom of this page.
The City of Toronto did similar counts at College & Spadina in September 2010. On a clear sunny day in September, there were only 408 bikes per hour in the afternoon rush hour. In 3 years, bicycle traffic on College St has increased by 67%. During rush hour, the westbound College St bike lane moves about the same number of people as both westbound vehicular travel lanes. In other words, if given a safe option, a significant number of people will commute by bike.
"It's incredible," commented Jared Kolb, Executive Director of Cycle Toronto. "It's the first time in Toronto's history that we've seen a major arterial roadway in Toronto move more bicycles than motor vehicles in a single direction. It's a testament to the increasing importance bicycles play in Toronto's transportation mix."
Reducing congestion & expanding transit are widely discussed themes across Toronto. Bicycles, however, have largely been absent in Toronto's transit discussion. Investments in bicycle infrastructure are low cost, high impact interventions to get Torontonians moving. 19% of the roadway on College St at Spadina Ave is reserved for cyclists and 81% is reserved for motor vehicles. However, in the peak of rush hour, the westbound bicycle lane on College St carried more vehicular traffic than both westbound motor vehicle lanes combined.
Network of protected bike lanes and low speed roads needed to get Toronto moving
55% of all trips in Toronto are less than 7 kilometres in length, which can typically be travelled by bicycle in 30 minutes or less (Source: Road to Health). Cycling is an increasingly critical way in which Torontonians move around the city. According to recent polling data, 7% - or 182,000 Torontonians - are now cycling every day. 69% of Torontonians want to ride more often, but the lack of safe cycling infrastructure is holding them back.
Toronto's bicycle network inadequately serves the city. The 2001 Bike Plan called for 495 kms of bicycle lanes to be built; today, the city has just 111.6 kms of bicycle lanes (Source: City of Toronto). Last year, Toronto added net zero kms of bicycle lanes. Significantly, we have fewer kilometres of bicycle lanes today than we did in 2009. Even the College St bike lanes, where the counts were conducted, only run for 2.2km from one end to the other.
City Council must get serious about cycling and accelerate the installation of safe cycling infrastructure across Toronto. Specifically,
- Transit: All higher-order transit lines such as subways and LRTs should be supported by bicycle lanes and comprehensive bicycle parking. The Bloor-Danforth, Yonge and University corridors should all have high quality physically separated bike lanes, giving transit riders an alternative to avoid overcrowded subways.
- Schools: All schools should be connected by networks of bicycle lanes and low-speed residential roads and supported by comprehensive bicycle parking to enable students to get to school by bicycle.
- Winter Cycling: The City should develop a comprehensive network of snow routes for cyclists that receive priority clearing that helps Torontonians to stay on their bicycles across the 4 seasons.
Cycling infrastructure is an affordable, efficient and quick way to get Torontonians moving. With the right investment, College St is an example of the gains we can make city-wide.
Cycle Toronto is a diverse, member-supported organization that advocates for a healthy, safe cycling-friendly city for all.
Attachment | Size |
College St Graphic Final | 180.48 KB |


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OFFICE ASSISTANT Bilingual, Engl/Span. Strong gen. offc. computer skills. Accounting skills a plus More info |
Kendall Toyota, The Capital of Toyota, and West Kendall Toyota is searching for experienced Automoti More info |
Villar Gallery is looking for a dynamic and multitask Receptionist at the flooring and construction More info |


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From Wikipedia, the free encyclopedia - View original article
Flywheel energy storage (FES) works by accelerating a rotor (flywheel) to a very high speed and maintaining the energy in the system as rotational energy. When energy is extracted from the system, the flywheel's rotational speed is reduced as a consequence of the principle of conservation of energy; adding energy to the system correspondingly results in an increase in the speed of the flywheel.
Most FES systems use electricity to accelerate and decelerate the flywheel, but devices that directly use mechanical energy are being developed.[1]
Advanced FES systems have rotors made of high strength carbon filaments, suspended by magnetic bearings, and spinning at speeds from 20,000 to over 50,000 rpm in a vacuum enclosure.[2] Such flywheels can come up to speed in a matter of minutes — much quicker than some other forms of energy storage.[2]
Contents |
A typical system consists of a rotor suspended by bearings inside a vacuum chamber to reduce friction, connected to a combination electric motor and electric generator.
First generation flywheel energy storage systems use a large steel flywheel rotating on mechanical bearings. Newer systems use carbon-fiber composite rotors that have a higher tensile strength than steel but are an order of magnitude less heavy.[3]
Magnetic bearings are sometimes used instead of mechanical bearings, to reduce friction.
The expense of refrigeration led to the early dismissal of low temperature superconductors for use in magnetic bearings. However, high-temperature superconductor (HTSC) bearings may be economical and could possibly extend the time energy could be stored economically. Hybrid bearing systems are most likely to see use first. High-temperature superconductor bearings have historically had problems providing the lifting forces necessary for the larger designs, but can easily provide a stabilizing force. Therefore, in hybrid bearings, permanent magnets support the load and high-temperature superconductors are used to stabilize it. The reason superconductors can work well stabilizing the load is because they are perfect diamagnets. If the rotor tries to drift off center, a restoring force due to flux pinning restores it. This is known as the magnetic stiffness of the bearing. Rotational axis vibration can occur due to low stiffness and damping, which are inherent problems of superconducting magnets, preventing the use of completely superconducting magnetic bearings for flywheel applications.
Since flux pinning is the important factor for providing the stabilizing and lifting force, the HTSC can be made much more easily for FES than for other uses. HTSC powders can be formed into arbitrary shapes so long as flux pinning is strong. An ongoing challenge that has to be overcome before superconductors can provide the full lifting force for an FES system is finding a way to suppress the decrease of levitation force and the gradual fall of rotor during operation caused by the flux creep of SC material.
Compared with other ways to store electricity, FES systems have long lifetimes (lasting decades with little or no maintenance;[2] full-cycle lifetimes quoted for flywheels range from in excess of 105, up to 107, cycles of use),[4] high energy density (100-130 W·h/kg, or 360-500 kJ/kg),[4][5] and large maximum power output. The energy efficiency (ratio of energy out per energy in) of flywheels can be as high as 90%. Typical capacities range from 3 kWh to 133 kWh.[2] Rapid charging of a system occurs in less than 15 minutes.[6] The high energy densities often cited with flywheels can be a little misleading as commercial systems built have much lower energy density, for example 11 W·h/kg, or 40 kJ/kg.[7]
The maximum energy density of a flywheel rotor is mainly dependent on two factors, the first being the rotor's geometry, and the second being the properties of the material being used. For single-material, isotropic rotors this relationship can be expressed as[8]
where the variables are defined as follows:
The highest possible value for the shape factor of a flywheel rotor, is , which can only be achieved by the theoretical constant-stress disc geometry.[9] A constant-thickness disc geometry has a shape factor of , while for a rod of constant thickness the value is . A thin cylinder has a shape factor of .
For energy storage purposes, materials with high strength, and low density are desirable. For this reason, composite materials are frequently being used, in advanced flywheels. The strength-to-density ratio of a material can be expressed in the units [Wh/kg], and values greater that 400 Wh/kg can be achieved by certain composite materials.
Several modern flywheel rotors are made from composite materials. Examples include the Smart Energy 25 flywheel from Beacon Power Corporation,[10] and the PowerThru flywheel from Phillips Service Industries.[11]
For these rotors, the relationship between material properties, geometry and energy density can be expressed by using a weighed-average approach.[12]
In the 1950s, flywheel-powered buses, known as gyrobuses, were used in Yverdon, Switzerland and there is ongoing research to make flywheel systems that are smaller, lighter, cheaper and have a greater capacity. It is hoped that flywheel systems can replace conventional chemical batteries for mobile applications, such as for electric vehicles. Proposed flywheel systems would eliminate many of the disadvantages of existing battery power systems, such as low capacity, long charge times, heavy weight and short usable lifetimes. Flywheels may have been used in the experimental Chrysler Patriot, though that has been disputed.[13]
Flywheels have also been proposed for use in continuously variable transmissions. Punch Powertrain is currently working on such a device.[14]
During the 1990s, Rosen Motors developed a gas turbine powered series hybrid automotive powertrain using a 55,000 rpm flywheel to provide bursts of acceleration which the small gas turbine engine could not provide. The flywheel also stored energy through regenerative braking. The flywheel was composed of a titanium hub with a carbon fiber cylinder and was gimbal-mounted to minimize adverse gyroscopic effects on vehicle handling. The prototype vehicle was successfully road tested in 1997 but was never mass-produced.[15]
Flywheel systems have also been used experimentally in small electric locomotives for shunting or switching, e.g. the Sentinel-Oerlikon Gyro Locomotive. Larger electric locomotives, e.g. British Rail Class 70, have sometimes been fitted with flywheel boosters to carry them over gaps in the third rail. Advanced flywheels, such as the 133 kW·h pack of the University of Texas at Austin, can take a train from a standing start up to cruising speed.[2]
The Parry People Mover is a railcar which is powered by a flywheel. It was trialled on Sundays for 12 months on the Stourbridge Town Branch Line in the West Midlands, England during 2006 and 2007 and was intended to be introduced as a full service by the train operator London Midland in December 2008 once two units had been ordered. In January 2010, both units are in operation.[16]
FES can be used at the lineside of electrified railways to help regulate the line voltage thus improving the acceleration of unmodified electric trains and the amount of energy recovered back to the line during regenerative braking, thus lowering energy bills.[17] Trials have taken place in London, New York, Lyon and Tokyo,[18] and New York MTA's Long Island Rail Road is now investing $5.2m in a pilot project on LIRR's West Hempstead Branch line.[19]
Flywheel power storage systems in production as of 2001 have storage capacities comparable to batteries and faster discharge rates. They are mainly used to provide load leveling for large battery systems, such as an uninterruptible power supply for data centers as they save a considerable amount of space compared to battery systems.[20]
Flywheel maintenance in general runs about one-half the cost of traditional battery UPS systems. The only maintenance is a basic annual preventive maintenance routine and replacing the bearings every five to ten years, which takes about four hours.[6] Newer flywheel systems completely levitate the spinning mass using maintenance-free magnetic bearings, thus eliminating mechanical bearing maintenance and failures.[6]
Costs of a fully installed flywheel UPS are about $330 per kilowatt.[21] In combination with a diesel generator set or integrated design, it supplies continuous power as long as there is fuel.
A long-standing niche market for flywheel power systems are facilities where circuit-breakers and similar devices are tested: even a small household circuit-breaker may be rated to interrupt a current of 10,000 or more amperes, and larger units may have interrupting ratings of 100,000 or 1,000,000 amperes. The enormous transient loads produced by deliberately forcing such devices to demonstrate their ability to interrupt simulated short circuits would have unacceptable effects on the local grid if these tests were done directly from building power. Typically such a laboratory will have several large motor-generator sets, which can be spun up to speed over some minutes; then the motor is disconnected before a circuit breaker is tested.
Other similar high power applications are in tokamak fusion (like the Joint European Torus) and laser experiments, where very high currents are also used for very brief intervals. JET has two 775 ton flywheels that can spin up to 225 rpm.[22]
The Incredible Hulk roller coaster at Universal's Islands of Adventure features a rapidly accelerating uphill launch as opposed to the typical gravity drop. This is achieved through powerful traction motors that throw the car up the track. To achieve the brief very high current required to accelerate a full coaster train to full speed uphill, the park utilizes several motor generator sets with large flywheels. Without these stored energy units, the park would have to invest in a new substation and risk browning-out the local energy grid every time the ride launches.
Since FES can store and release energy quickly, they have found a niche providing pulsed power (see compulsator).
The FIA has re-allowed the use of KERS (see kinetic energy recovery system) as part of its Formula One 2009 Sporting Regulations.[23] which is now back in for the 2011 Formula 1 season. Using a continuously variable transmission (CVT), energy is recovered from the drive train during braking and stored in a flywheel. This stored energy is then used during acceleration by altering the ratio of the CVT.[24] In motor sports applications this energy is used to improve acceleration rather than reduce carbon dioxide emissions—although the same technology can be applied to road cars to improve fuel efficiency.[25]
Automobile Club de l'Ouest, the organizer behind the annual 24 Hours of Le Mans event and the Le Mans Series, is currently "studying specific rules for LMP1 which will be equipped with a kinetic energy recovery system."[26]
Beacon Power opened a 20 MW, (5 MWh over 15 mins)[27] flywheel energy storage plant in Stephentown, New York in 2011.[28] Lower carbon emissions, faster response times and ability to buy power at off-peak hours are among some advantages of using flywheels instead of traditional sources of energy for peaking power plants.[29]
Flywheels may be used to store energy generated by wind turbines during off-peak periods or during high wind speeds.
Beacon Power recently began testing of their Smart Energy 25 (Gen 4) flywheel energy storage system at a wind farm in Tehachapi, California. The system is part of a wind power/flywheel demonstration project being carried out for the California Energy Commission (Beacon Power Press Release March 2010).
Friction motors used to power many toy cars, trucks, trains, action toys and such, are simple flywheel motors.
In industry, toggle action presses are still popular. The usual arrangement involves a very strong crankshaft and a heavy duty connecting rod which drives the tup. Large and heavy flywheels are driven by electric motors but the flywheels only turn the crankshaft when clutches are activated.
Flywheels are not as adversely affected by temperature changes, can operate at a much wider temperature range, and are not subject to many of the common failures of chemical rechargeable batteries.[30] Unlike lithium ion polymer batteries which operate for a finite period of roughly 36 months, a flywheel can potentially have an indefinite working lifespan. Flywheels built as part of James Watt steam engines have been continuously working for more than two hundred years.[31] Working examples of ancient flywheels used mainly in milling and pottery can be found in many locations in Africa, Asia, and Europe.[32][33] They are also less potentially damaging to the environment, being largely made of inert or benign materials. Another advantage of flywheels is that by a simple measurement of the rotation speed it is possible to know the exact amount of energy stored. However, use of flywheel accumulators is currently hampered by the danger of explosive shattering of the massive wheel due to overload.
One of the primary limits to flywheel design is the tensile strength of the material used for the rotor. Generally speaking, the stronger the disc, the faster it may be spun, and the more energy the system can store. When the tensile strength of a flywheel is exceeded the flywheel will shatter, releasing all of its stored energy at once; this is commonly referred to as "flywheel explosion" since wheel fragments can reach kinetic energy comparable to that of a bullet. Consequently, traditional flywheel systems require strong containment vessels as a safety precaution, which increases the total mass of the device. Fortunately, composite materials tend to disintegrate quickly to red-hot powder once broken, instead of large chunks of high-velocity shrapnel. Still, many customers of modern flywheel energy-storage systems prefer to have them embedded in the ground to halt any material that might escape the containment vessel.
An additional limitation for some flywheel types is energy storage time. Flywheel energy storage systems using mechanical bearings can lose 20% to 50% of their energy in 2 hours.[34] Much of the friction responsible for this energy loss results from the flywheel changing orientation due to the rotation of the earth (a concept similar to a Foucault pendulum). This change in orientation is resisted by the gyroscopic forces exerted by the flywheel's angular momentum, thus exerting a force against the mechanical bearings. This force increases friction. This can be avoided by aligning the flywheel's axis of rotation parallel to that of the earth's axis of rotation.
Conversely, flywheels with magnetic bearings and high vacuum can maintain 97% mechanical efficiency, and 85% round trip efficiency.[27]
When used in vehicles, flywheels also act as gyroscopes, since their angular momentum is typically of a similar order of magnitude as the forces acting on the moving vehicle. This property may be detrimental to the vehicle's handling characteristics while turning. On the other hand, this property could be utilized to keep the car balanced so as to keep it from rolling over during sharp turns. Conversely, the effect can be almost completely removed by mounting the flywheel within an appropriately applied set of gimbals, where the angular momentum is conserved without affecting the vehicle (see Properties of a gyroscope). This doesn't avoid the complication of gimbal lock, and so a compromise between the number of gimbals and the angular freedom is needed. A single gimbal, for instance, could free a car for the 360 degrees necessary for regular driving. However, for instance driving up-hill would require a new gimbal mechanism with a new degree of freedom. Two gimbals would theoretically solve this problem and never lock unless the car rolls.
An alternative solution to the problem is to have two joined flywheels spinning synchronously in opposite directions. They would have a total angular momentum of zero and no gyroscopic effect. A problem with this solution is that when the difference between the momentum of each flywheel is anything other than zero the housing of the two flywheels would exhibit torque. Both wheels must be maintained at the same speed to keep the angular velocity at zero. Strictly speaking, the two flywheels would exert a huge torqueing moment at the central point, trying to bend the axle. However, if the axle were sufficiently strong, no gyroscopic forces would have a net effect on the sealed container, so no torque would be noticed.


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Billboard advertising accounted for 17,6% of 2013 revenues. It is the largest segment of the outdoor advertising market.
JCDecaux considerably diversified its activity into billboard advertising in 1999 with the acquisition of Avenir, the outdoor advertising division of Havas. JCDecaux is the European leader in billboards with 191,000 advertising panels.
By basing its action on the qualitative aspect of the display media, JCDecaux has revolutionized this market with flagship products such as new-generation scrolling panels known in France as 'Vitrines'. More attractive, and less numerous, than traditional billboard systems, they produce a greater impact when placed on strategic sites, back-illumination and designed to blend harmoniously into the surrounding environment.
As of 31st December 2013, the geographic distribution of our billboards was as follows:
(1) Includes Austria, Belgium, Bulgaria, Croatia, Czech Republic, Denmark, Estonia, Finland, Germany, Italy, Latvia, Lithuania, the Netherlands, Norway, Poland, Portugal, Republic of Ireland, Slovenia, Slovakia, Spain, Sweden and Turkey. (2) Includes China, Singapore and Thailand. (3) Includes Telephone Kiosk panels. (4) USA. (5) Includes Kazakhstan, Qatar, Russia, Ukraine and Uzbekistan.source: Annual Report


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5 Most Beautiful Gardens in Virginia
Published on June 22nd, 2011.
If planning a trip to Virginia, then waste no time by thinking of heading anywhere else. When it comes to Virginia, the one true fact that is beneficial to all is that it is the home of many things. By this being so; especially in this case, coming across a lot of unique gardens will be beyond extremely easy to accomplish. From small gardens to large ones, Virginia has literally hundreds (if not) thousands of gardens of any size throughout its spacious landscape.I found some more information here. With that said, the following information will touch on the five most beautiful gardens that are found in all of Virginia.
Lewis Ginter Botanical garden
Located in Richmond, Virginia, this 40 acre botanical garden is bordered by a lake and has well over 200 orchids and several other beautiful flowers.
Green Spring Gardens
This 27 acre area of land is the home of many gardens. When visiting here, one thing that will prove to be true is that you will find a garden that is beyond perfect.
Maymont offers a large park and several exquisite gardens.
Colonial Gardens of Williamburgs Ash lawn
Taking the time out to visit Colonial Gardens or Ash Lawn will allow you to witness over 90 acres of both greens and beautiful gardens.
Filled under Uncategorized.


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Welcome to the Alderney Tennis Club Alderney has a well deserved reputation for its hospitality; new members and visitors to the Island can be sure of a warm welcome when they visit our Tennis Club and enjoy our Club's facilities. Four separate, county size courts are available for hire and whether you are a beginner, a regular club player, or a veteran wewill be pleased to welcome you ‿and that goes for children too ! Our volunteer Club coaches have regular sessions for children of all ages throughout the summer months ‿and to a more limited extent throughout the winter. In fact, Alderney Tennis Club boasts the largest ongoing junior membership in the Channel Islands, with as many as sixty youngsters of all levels turning out on Saturday mornings and smaller groups receiving coaching during the week. Small groups of senior or veteran players are welcome too and, given warning, we can organize mini tournaments against Alderney Club players. Weather permitting, watches replica we have a 'round robin‿Senior Club Night every Wednesday evening during the summer months, with a barbecue to follow, to which visitors are most welcome. We are proud that our Club was built and funded entirely by its members and we would find it difficult to maintain the Club's facilities in good order without the funds generated by junior and senior memberships ‿and of course our visitors. So don't forget to bring your racquet and we look forward to welcoming you to our delightful Club. Ray Parkin If Kobe Bryant 29 return nba,will again be injured? lebron james in 2014 three-peat nba mvp and kevin durant regular season leading scorer,their equipment kobe bryant shoes,KD shoes,lebron shoes store. |
Alderney Tennis Club Website hosted by Island Computers & Web Design |


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Your Pop Alternative Source
Chapter Two - Arrivals.
Walking off the plane I felt the warm glow of the Californian sun it was beautiful out and it felt like I was finally home. Though it was nine in the morning and most of the city was sleeping. It still felt nice to be back.
If I were back in Newfoundland I would still be asleep right now I was quite awake. Between sugar rushes and the constant checking of how many minutes until landing I had allot of time to sleep on the flight.
On the plane I had changed from sweats into black skinnie capris, a tank top, studded belt, leather fingerless gloves and my long dark brown hair was straight as I was wearing my cherrytree converse. Last summer we had all painted the logo onto our shoes to show what we represented.
I walked into LAX picking up my suitcase as my backpack was on my back, I had tucked my purse into my backpack to save myself the bulk.
I was on my way to starbucks for a iced mocha when I felt someone grabbing my free hand as I turned to see who it was I let out a scream starteling and waking up all of LA.
"Kate!" I screamed as we both jumped at eachother her short hair falling arround her face in a soft mannor as her makeup was flawlessly done as always. Her outfit similar to mine except she was wearing a blue tank rather the black.
"Nessa! Gott I missed you!" Her voice was happier then it usually was as she was just as excited for camp as I was.
I looked next to her as I could see four cases worth of clothes and god only knows what else. I was now glad camp only had metal detectors rather then the cavity searches my old camp used to have.
It would take you a week just to go through one of Kate's suitcases let allone all four.
"Pack light much." I laughed as she gasped looking at my bags.
"You only brought two bags? Ness we are here for two months!" she pointed to my suit case and back pack in utter terror. I rolled my eyes as I let go of her grabbing my suit case heading to the cafe inside of the airport that was big enough to be a small island.
I was about to sit down when I heard a voice calling.
"Rockgirl do you ever stop with the caffeine? God you picked up some horrible habbits from camp last year including not calling your director when you got off the plane."
I turned arround to see the grammy nominated producer looking at me and Kate with a smirk on his face.
We both giggled.
"And Jumbie, your starting to pick up her habits too. What are we going to do with you?" he laughed ordering himself a coffee. Looks like were not the only ones who need a morning perk up.
"Taking us to camp would be a good start Tony." I laughed as Kate and I got our bags together.
"What did you do put your entire house into your bags?" he laughed again as we began for the black covertible with the logo on the hood as I could see a blond haired man sitting in shot gun.
"It's two months! I needed clothes and shoes and make up to look pretty!" Kate whined in a girly tone as I laughed.
"I look great and I fit all my stuff into one bag , although I do have four grand on my visa in american dollars. Thank god for my job." I laughed as we jumped into the car.
"You two stop bickering and lets hit the road. Red wood is a an hour away and you need to get set up. You two are the first here." Dean smiled getting out of the car giving us both a quick hug.
"Welcome back girls." he smiled as we all got into the car as Tony began to drive.
"Thanks Dean." we said in sync as Tony began to drive I put my head back on the seat.
It felt nice to be back in LA.
© 2015 Created by Cherrytree.


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6801 W Branch Hwy
Route 15
Lewisburg, PA 17837
B. Z. Motors maintains a comprehensive inventory of quality used Chrysler, Dodge, Jeep, RAM and pre-owned cars, trucks, vans, and SUVs in Lewisburg. If you are looking for a used Ram in Beaver Springs, we can help you find one right here in Lewisburg. All of our used vehicles go through an extensive inspection before hitting the pre owned car lot, and we strive to ensure that you buy a used car in Lewisburg PA which will be on the road for years to come. If you can't find a vehicle on our used car lot that suits your needs, fill out our CarFinder request form and we'll find it for you. Stop by our used car dealership at 6801 W Branch Hwy and take a test drive today! Check out our Lewisburg used car specials too! We're proud to provide used cars to Williamsport, Danville PA, Sunbury, and Beaver Springs.
More about buying a new or used car from B. Z. Motors in Lewisburg
Everyone here at the dealership is proud to provide select specials on used Chrysler, Dodge, Jeep and RAM vehicles. Take a look at our current deals and discounts today! If you can't find that perfect used car in Lewisburg on our pre owned car lot, consider buying a new Chrysler, Ram, Dodge, or Jeep from B. Z. Motors. Our car loan experts can work with you to build a car loan or Chrysler, Dodge, Jeep or RAM lease in Lewisburg around your budget because a new Chrysler, Dodge, Jeep or RAM may be more affordable than you think. Whether you buy new or used, B. Z. Motors' Chrysler, Dodge, Jeep and RAM auto parts and auto service departments in Lewisburg will make sure you are cruising in style for years to come. We look forward to seeing you soon.
* The advertised price does not include sales tax, vehicle registration fees, other fees required by law, finance charges and any documentation charges.
* Images, pricing and options shown are examples, only, and may not reflect exact vehicle color, trim, options, pricing or other specifications.
Enter your registered email address to request a password reset link.


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Sponsored by: Brakes Plus
Sep 7, 2011 1:15 PM by James H Egbert
The traffic accident just west of Academy Blvd on Palmer Park has partially blocked and closed eastbound Palmer Park due to emergency equipment in the roadway. Fire crews have investigated to see if the vehicle fire extended into the home when the car came to rest next to it. Only light smoke was seen in the home and no sign of fire damage. One patient was transported from the scene.
There was significant damage to some outside structures such as what appeared to be a gazebo.
2 months ago


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Review: Sayonara Siobhan
The highly-touted "Girls Year" has now turned into "The Year of the Girl," as the elimination of Siobhan Magnus leaves lone female Crystal Bowersox to duke it out with four guys. The 20 year-old glassblower is now preparing for her return home to Cape Cod, although who's to say she won't be boarding a spaceship instead? My friend Marc Nathan has suspected all along that Siobhan might be one of the aliens from the television show "V."
The Top 5 are now preparing for next week's Songs Of Sinatra, under the watchful eye of guest mentor Harry Connick, Jr. I have a feeling that the theme places the already-vulnerable Casey James (in the Bottom 2 again) at a distinct disadvantage, but this season certainly has a reputation as one where anything can happen. Big Mike rounded out last night's Bottom 3, but for some reason I can already picture him wearing a Frank Sinatra fedora and crooning one of those Rat Pack classics.
Here are a few other random thoughts and observations from the results show:
* Some of the top acts in country music took to the stage last night, including Lady Antebellum, Rascal Flatts, and…Shakira? The latin belly dancer/singer's presence made no sense to me initially, but with the help of Rascal Flatts, her song "Gypsy" ended up fitting in quite nicely.
* Sons of Sylvia are the opening act on Carrie Underwood's tour and they are certainly worth keeping an eye on. Their song "Love Left To Lose" sounded like a hit to my ears, but here's my question: what radio format? They seemed a little too goth to be a country act, but I imagine their dark attire and the possessed/intense gaze of the lead singer might be appealing to fans of the "Twilight" craze.
* Speaking of vampires, what was up with that Ford music video? Expect their convertible sales to plummet as consumers give in to their fears of being attacked by violent, ruthless bloodsuckers like Aaron Kelly.
* Sorry Adam Lambert, but my award for 2010's Best Live Performance on the Idol Stage now goes to Lady Antebellum. They sounded phenomenal, had great stage presence, and proved that they deserved all of their recent Grammy and CMA Awards. Plus, my friend Lee Williams says that lead singer Hillary Scott reminds him of a more grounded version of Fergie from the Black Eyed Peas. Much more grounded.
What did you think of last night's show? Were you surprised by Siobhan's exit? Who will likely be the next to go? Sound off below with a comment!


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Only not, because I've programmed this entry to appear after I leave. Bazinga!
I would really like to petition to the universe to get about four more hours in every day. I'm not asking for much. Just two more hours in the morning to sleep, and two more hours at night to finish work and probably watch Top Gear.
The second request on my petition to the universe is that Netflix won't get rid of Top Gear on Instant Watch because we haven't watched all the episodes we've wanted yet. Then I would humbly include a clause requesting that Netflix doesn't double in price.
Bottom line: I've been busy. But that's not new news. I think if I wasn't so stubborn about getting an exorbitant amount of sleep (going to bed at 9 PM and waking up at 5:30 AM has worked out well for me), I'd probably have more than enough time to surf the internet do my homework.
But things have been going well. Fall is here! It's both chilly and sunny, and that is my favorite.


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© 2011 St Marys Motors all rights reserved Fri Mar 06 2015 06:03:38 GMT-0500 (Eastern Standard Time)
Used Cars in Lexington Park are sold at St. Mary's Motors (Saint Mary's Motors). We have customers that come from Waldorf, Prince Frederick, Leonardtown, California, Solomons Island and even Prince Georges County. Every buyer qualifies and is guaranteed top level service and we have buy now pay now or buy here pay here programs in place. At St. Mary's Motors we believe that each customer will drive away a used car today with only little money down. You can have bad credit, little credit or no credit when it comes to purchasing your used car. Waldorf Used Cars doesn't compare to the type of cars we carry. Everyone drives away with a luxurious dealer financed vehicle the same day. You can reach our dealership at 301-737-6400 and our address is 21555 Great Mills Road, Lexington Park, MD 20653.


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Item Details:
Make this summer the brightest yet with our SW Mirrored Style #54060! These retro style sunglasses have a bright plastic frame with colorful mirrored lenses.? The UV400 sun protection takes the worry out of wearing for your next concert, beach party, or sporting event.
- Plastic Frame
- UV400 Sun Protection
- Available colors:
Compare to Ray-Ban Wayfarer®


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Thin Ice
Written by on April 6th, 2012Thin Ice is about an asshole who gets into deep trouble with another asshole because of their collective assholery. Sound fun? It's torture. In addition to the oily, cheap, thoroughly unlikable main character, an insurance salesman named Mickey (Greg Kinnear), there's the nagging fact that the film, directed by Jill Sprecher (Thirteen Conversations About One Thing) and co-written by her and her sister Karen, is a blatant Fargo rip-off, set during a Wisconsin winter and centered on a desperate man with money problems. The only things differentiating Thin Ice from the Coen brothers' gem are 1) a lack of Midwestern accents and 2) a lack of entertainment value.
Mickey is illogically drawn as an award-winning salesman and convention speaker who nevertheless can barely keep a staff and has to siphon funds from his business for personal use. When a new hire tells him about a prospective customer, Mickey steals the sale, talking a senile retiree named Gorvy (Alan Arkin) into buying more insurance than he needs. He also discovers that Gorvy owns a rare violin that's worth quite a chunk of change. Let the conniving ensue.
The first half of the film progresses almost episodically, with scenes such as Mickey getting robbed by a seductive drunk or trying to win back his ex-wife (Lea Thompson) really having little to do with each other. It's not until he meets a shady locksmith (Billy Crudup) at Gorvy's place that an actual plot kicks in. Theft is on each of their minds, but when they're almost caught, things grow much more dire fast.
Kinnear is admittedly good at playing an unethical jerk, but that's actually a problem: It's difficult to root for a guy to wriggle his way out of a bad situation when he's intolerable. Crudup's Randy, meanwhile, is too much of a loose cannon to be taken seriously, and Arkin's Gorvy is more demanding-old-man irritating than pitiable. The film's worst sin, though, is its resolution, which is needlessly complicated and relies on way too many coincidences to be believed. It's also probably nonsensical upon closer inspection, but it's doubtful that any viewer will want to inspect Thin Ice more closely.


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Software Developers
What do you need from your software? The world is your oyster.
Here at Eskdale Solutions, in addition to web design, we write all our own programming and create all our own software which means we know it inside-out, enabling us to give you the most comprehensive support and advice.
So? Why should you be bothered about that?
It means that all our web software is thoroughly tried and tested, giving you a solution that is functional, easy to use and reliable. As technology is constantly evolving, you need software that can integrate additional applications and developments as your business needs them. Our software can do that, we don't believe in the one size fits all philosophy. We believe in tailoring our software and services around the exact needs of your business.


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Did you know that today (February 1st) is National Freedom Day? It's not technically a holiday – it's a day of observance that honors the signing of the resolution that proposed the 13th Amendment of the US Constitution to outlaw slavery. President Harry S Truman signed a bill in 1948 that proclaims February 1st as National Freedom Day in the US and over the years, National Freedom Day has become a day to promote good will, equality and to appreciate freedom.
For National Freedom Day 2012, I propose that we all clean out our coupon binders and organizers and gather up all the coupons that expired on 1/31/2011 and mail them out to a military family, who serves our country and helps keep us free!
If you have not yet adopted an overseas military family to mail your coupons to, you can do so here!


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December 10, all Cummer lots across Riverside Avenue from the museum will be closed for a complete renovation. Construction is scheduled to be completed by Spring 2013. During this period, visitors…
Tag Archives: Dedicate a Brick Campaign
Cummer Parking Transformed
by Holly Keris, Curator in Behind the Scenes, Gardens
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Action Bronson - Big Bad & Dangerous Feat. Smoke DZA (Prod. By 183rd)
Big Bad & Dangerous Action Bronson Feat. Smoke DZA Produced by 183rd
Listen to Big Bad & Dangerous (Prod. by 183rd), the new track by Action Bronson featuring Smoke DZA which was dropped on Thursday, August 25th, 2011.
Stream Big Bad & Dangerous (Prod. by 183rd), the newest drop from Action Bronson which features Smoke DZA. The cut was released on Thursday, August 25th, 2011. Action Bronson continues to impress with each new leak, and Big Bad & Dangerous (Prod. by 183rd) is no exception. It's strengthens Action Bronson's already impressive body of work, which has seen positive change over the years. We're most definitely anticipating Action Bronson's next offering.
Check out Action Bronson on Muslim Wedding (Prod By Harry Fraud). If you're down, make sure to visit Action Bronson's profile page for the newest info, news, songs, and mixtapes. Follow Action Bronson on Facebook and Twitter, if you aren't already.
Is this a good combination? Can you appreciate the bars here?


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About BadgerLink
BadgerLink is Wisconsin's online library which provides access to licensed content such as magazines, newspapers, scholarly articles, videos, images, and music. These resources are provided exclusively for use by all Wisconsin residents and are materials that are not available through regular search engines such as Google.
Who can benefit from the BadgerLink resources? All Wisconsin residents including...
Students, Educators, and Librarians! BadgerLink provides access to many educational resources, including:
- 3,100 royalty-free songs and sound effects
- 8,000+ full text magazines and journals
- Primary sources like firsthand accounts and American foundational documents
- Standards-based content including reference books, encyclopedias, photos, maps, flags, animations, and videos
- STEM (Science, Technology, Engineering and Math) materials such as science experiments and skill-building practice tests
- Test preparation materials and practice tests for ACT, SAT, AP, ASVAB, GED, and more!
Everyone Else! BadgerLink provides resources to those interested in a variety of other areas:
- Genealogists and local history buffs can access more than one billion full text newspaper articles from 1607 to the present and use tools like Census, Revolutionary war, and Freedman's Bank records
- Investors can use industry reports, market research reports, SWOT analyses, and full text business journals
- Job seekers can find test preparation materials, practice tests, business writing and interviewing tutorials, and company profiles
- Professional and amateur mechanics can find auto repair manuals, schematics, and wiring guides
- Seekers of health information can use health fact sheets, reports, drug guides, medical videos, and animations
- A number of BadgerLink resources can be accessed using text-to-speech and offer a translation feature for more than 25 languages!
BadgerLink is managed by the Resources for Libraries and Lifelong Learning team within the Wisconsin Department of Public Instruction, Division for Libraries and Technology, in cooperation with public, school, academic, special libraries, and Internet Service Providers. BadgerLink services began in July, 1998 and the project is supported by $2.2 million from the Universal Service Fund per year with partial support provided by the Institute of Museum and Library Services. By purchasing and providing library content on a statewide basis, BadgerLink saves Wisconsin libraries and residents approximately $74 million dollars per year.
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Throw on this Legend Authentic Football Font performance tee by Nike and display your Texans pride while you're pumping iron or scrimmaging on the field! It features team-colored "Houston Texans Football" lettering printed across the front and flat seams designed to reduce irritation from chafing and seam-stacking, which can result when layers have seams in the same place. It also features ergonomic seaming that matches the contours of the body for smooth, non-restrictive movement and Nike's patented Dri-FIT technology to keep you dry, cool and comfortable no matter how hard you work or play.
- 100% Polyester fabric
- Dri-FIT technology for ultimate comfort
- Imported
- Officially licensed NFL performance shirt
- Reinforced taped collar seam
- Screen print graphics
- Tagless collar
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- Authentic Look
- Quality Construction
- Shows Off Team Pride
- Stylish
Best Uses
- Anytime
My husband was so surprised when I got this for him and was even more surprised when I told him how little I had to pay:-)
Good quality for a great price!
- Sizing:
- Feels true to size
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text: > It's XML, almost every single language has a way to parse it and could > in fact either become a fe or be, with a little hacking, if it was done > in a shell script, we would be limited to that single interface. (that > being a shell) [Disclaimer: I don't really know what I'm going to talk about, so if you want to correct me so I finally _do_ know what I will be talking about in the future. Right now I'm just going to write down what my gut tells me. I'll be writing as if I'm the expert (makes it easier to write instead having to add "I think" or "I believe" or "something to that effect" every other sentence ;)] One of the barriers shell scripting introduces is when we need it to communicate with a front-end. Ideally we won't have to run the backend or even know it's there. We start out front-end, say QT based, and click on a "Start install" button. How would we have bash talk back to the QT app? As bash has no XML support I'm aware of, it'll have to resort to echo'ing a status to a file, stdout, stderr, or QT's stdin and QT will have to interprete that 'echo' and do something with it. This becomes a little bit harder when it has to be done over a network. I suppose bash could start a c program that makes a network connection to the QT app, dumps some status message, waits for reponse. To me I guess this would need to be a continuous open socket so the fe and be can send message at any given time. I also see problems with bash waiting for input. Perhaps an extra daemon can SIGALRM1 bash or something. That i won't begin to guess. So I guess technically we could stop using XML and start using shell scripts, but when we get to networking support I'm afraid bash won't meet our goals. If we were to use XML-RPC (or RPC-XML; whichever way) we could tell QT "interrupt backend, send this new profile". Over RPC-XML we send an XML profile, be gets it, does not need to do anything with, can run it immediately (then again you could tell the RPC thing to just send a bunch of command sequences to the shell on the other side and tell it "run this, until EOF.....commands.....EOF". Would it be feasible? -- Gerard Beekmans www.linuxfromscratch.org -*- If Linux doesn't have the solution, you have the wrong problem -*- -- Unsubscribe: send email to alfs-discuss-request at linuxfromscratch.org and put unsubscribe in the subject header of the message


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Free Photo Archive of over 30,000 vintage photographs. Find people and the places were they lived. Search for your surnames. Find photos of your ancestors. Make connections with genealogy cousins. Add your family's photos. |
Pine Flats School 1907 or 1908
Pine Flats School, Pine Flats, Indiana County, Pa.
Back row, left to right, Logan Parry, unknown, Mary Parry, Teressa Parry, seven unknown girls, Sara Roberts.
Second row, all unknown, except Etta Parry, far right.
Front row, two unknown girls, William Parry, rest unknown.
Photo taken in 1907 or 1908.
Recognize anyone? Please let me know.
To make this photo larger, click on the word "original" above.
Your Grandmother, Your Aunts & Uncles, Your Great-Grandfather - who will you find in the U.S. Yearbook Collection of yearbooks from the early 1900s to the 1980s. Thousands of full high school and college yearbooks scanned and on line.


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The final Double Duck arc ends here as we prepare for a brand new story in Donald Duck & Friends! The world's favorite feathered federal agent, Donald Duck, is undercover in Egypt face-to-face with the would be kidnappers of former Agency chief, Felino Felinys. It's going to take some slippery work to get them both home safely, all while protecting the Agency's biggest secrets! The exciting conclusion to the fan favorite saga! Featuring the hilarious backup story "Bugged Duck!"
Preview: Donald Duck and Friends #358
Tue, September 14th, 2010 at 3:01pm PDT
- Story by
- Marco Bosco, Laura Shaw, Mark Shaw
- Art by
- Francesco D'Ippolito, Flemming Andersen
- Letters by
- Jose Macasocol Jr.
- Cover by
- Magic Eye Studios, Jake Myler
- Publisher
- Boom! Studios
- Cover Price:
- $2.99
- Release Date
- Sep 15th, 2010
- Browse for similar previews
<< CBGB #3 | Previews Archive | Farscape #11 >>


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Your Holiday Cocktail Guide
Check your list and check it twice to be sure these must-have holiday cocktail recipes are invited to the party. Then get ideas for what to serve, from party appetizers to celebrity chef-endorsed holiday meals, with your festive seasonal sips.
You can now save these recipes to your recipebook!»
You can now save these recipes to your recipebook!»
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March 2 2015 Latest news:
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Well this is a LOT better NA JR MR and GH for CH PT and CC... We have swapped Cautious, Downbeat Manager for Hungry, Confident, Manager....Disengaged, clueless coaches for motivated disciplined coaches.... and added an experienced man to help with recruiting and contracts, which will prove essential for an inexperienced business manager like Adams... JR is the link between Adams and DM for player contract stuff as well as his contacts for recruitment... and most of all... all 4 of them have played for or worked with the club before and want to be here... let's hope it all comes together
Tuesday, June 03, 2014


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You're Only As Strong As Your Brand's Identity
Think of brands that you have never had an experience with before.
Some you will hate, some you will love and others you will be indifferent about, well it's their brand identity that is causing that.
Most people will judge a company by their past experiences with it, if they have had any, but if not they will rely on that brand's identity, which can include word of mouth, work in the community, advertisements and anything else that they may have heard or see from that brand.
Lately we have been thinking more and more about our brand, here at the Deuce Group. We feel that although there isn't really any negative sentiment towards the brand, there isn't any positive coming from our brand's identity. People that have done business with us have been more than happy with our work, but we need to go beyond that.
In the coming weeks and months, you will notice changes in the way things our presented on the website, changes in the advertisements that are displayed and there will be a lot more giving back to our readers, customers and visitors.
Along with changing our identity, we will be changing our logo to a much more modern looking design.
Which companies do you think have a great brand identity and which ones not so much?
This entry was posted on Friday, May 11th, 2012 at 7:47 pm and is filed under Business, Design. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. You can skip to the end and leave a response. Pinging is currently not allowed.


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- Life As Mom - http://lifeasmom.com -
TGIF: Host Your Own Film Festival
Posted By Jessica Fisher On February 20, 2009 @ 8:04 pm In Family Fun,TGIF | 4 Comments
For several years the kids and I hosted a 3-Day, afternoon movie shindig for friends and neighbors. It was a great way to break up the winter blahs as well as socialize with other families. It doesn't cost much at all to have a good time.
Invite your friends and neighbors – I made up a little flyer with the dates, times, and movie selections and passed it out to friends and neighbors. This kind of invitation doesn't have to be elaborate. But, we invited a lot of people. I didn't assume that every family would come every day, so it was fine to invite a crowd.
Pick your dates and times – We chose midweek afternoons during a one-week span of time, Tuesday, Wednesday, Thursday. Showtimes started late enough for families to get there after school, but ended early enough for them to get home for dinner or other evening commitments.
Select your movies – You can do this however you want. You pick. Let your kids pick. Or take a poll of friends' preferences. (The latter option is obviously a litte more complicated and you won't be able to please everyone.) We stuck with mostly G rated films, but there are plenty [5] that also appeal to older children and adults. The most successful movie days were those when we played a movie that most guests had not seen before. A new DVD release is a good choice for this.
Acquire snacks – When you're hosting something big that happens over a week's time, it's difficult to be "the hostess with the mostess" without going broke. Ask families to bring their own water bottles and a snack to share. You can pop some corn [6], too. Provide large plastic cups for kids to pile their snacks into.
Provide toddler toys – Inevitably there will be little ones who really aren't interested in watching a movie. Have a bucket of Little People or Duplos nearby to entertain. Unless you really want to do "kid duty" all over your house, be firm that the crowd stay in the same location.
Enjoy time with fellow moms – Sometimes we watched the movie, sometimes we sat in the back and chatted. It was a great way to break up the week and relax while the kids had a good time.
Do you host a special get together for family and friends? Tell us about it.
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[5] there are plenty: http://www.lifeasmom.com/2009/01/tgif-7-great-kid-flicks.html
[6] pop some corn: http://www.lifeasmom.com/2008/05/tgif-time-to-pop-some-corn.html
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In true Indiana fashion, the weather changed and super fast. Why does everyone wonder why we all get sick? Probably because Indiana likes to freak out and change weather all the time, but I can't complain. Fall is my favorite season, and for all you Summer lovers out there let me explain why Fall is so awesome.
1. Sweatshirts/Uggs
Who doesn't love sweatshirts?! They are so comfy and soft. You don't have to worry about what you are wearing under them because you most likely won't take it off, but if you do get too hot then you can always take it off! I especially love my Phillies sweatshirt, thanks to my friend Hank I started getting interested in the Phillies and now I am debating whether to buy another sweatshirt. Buying a new sweatshirt might be a problem because I am really thinking about buying new Uggs. You may think Uggs are ugly, but they are so comfy. They can go with anything and feel so soft and warm. Don't judge the uggs by the outside it's what inside that matters
2. Apple Cider/Chai = Chaider or any Fall drink Starbucks offers.
My friend, Natasha, has seriously got me hooked on Chaider, I don't even know if that's how you spell it correctly, but it is Apple Cider and Chai Tea mixed together! It's so good! Not only that but since Fall is back that means Pumpkin Spice Lattes are here. Nothing is better than having a warm drink in cold weather. Plus who doesn't love Apple Cider?! So awesome.
3. Football
I am a huge fan of football. Being that I am from Indianapolis, I love the Colts. I can't wait until September 11th when the season starts. I've been a little worried with the whole Peyton situation, but nonetheless I am still pumped. Football in the fall is great. Tailgating and eating good off the grill food is so yummy. Plus when you go to games at Lucas Oil or any stadium for that matter there's no better football experience than that.
4. Leaves Changing!
Here in Indiana we are known for our leaves having this crazy change in color. I can't wait until leaves begin to change here at Butler. I heard it is so pretty through the Monon trail and just through out campus since we have so many trees! For any students though and anyone visiting Indiana, Brown County is a must. For the past couple years I have been going camping with my friends Lindsey and Sara to Happy Hollows in Brown County with their families. It's so pretty there and I'm so mad we can't do it this year because they go to Purdue and being that we both have the same homecoming as the high schooler's Fall Break, we can't go! I am going to miss it, so hopefully we get to go some other time!
5. Bonfires
They keep you warm, and you can make awesome food with bonfires. For example, Smores. Who doesn't love smores?! They can be messy but the gooey awesomeness of smores is the best part. Until Fall is here I have to suffice with microwave smores or the smores cupcake from The Flying Cupcake. The cupcake is awesome, but I still want the actual thing! Plus with bonfires I love that smell! Right now is perfect bonfire weather.
Sorry about my Fall rant, I am just a little too excited.


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Indie games developer Sean Hogan has offered free copies of Anodyne to those attempting to download the game through a Pirate Bay listings page.
After the 2D top-down adventure was posted on the Pirate Bay, Hogan issued a message within the comments section, asking users to vote for the game on Steam Greenlight if they enjoyed it.
"Hi, I'm one of the two guys who made Anodyne," Sean Wrote.
"It's neat that Anodyne's here and I'm glad that means more people can play it, though of course we'd love it if you bought the game. We're trying to get Greenlit [sic] on Steam so we'd really appreciate it if you and your friends gave us an up-vote".
Hogan also pointed users to his Twitter profile and asked for feedback regarding the game. He also posted six codes for others to download the game for free.
Discussing the move on his Twitter profile, Hogan asked "why fight piracy" and encouraged the community to spread the word about his game.
Why fight piracy? You should retweet and upvote this: reddit.com/r/gaming/comme...— Sean Hogan (seagaia) (@Seagaia2) February 11, 2013
While it is not customary for game studios to endorse the illicit file sharing of their products, Hogan is not the first developer to try and partner with Pirate Bay patrons.
Jonatan Soderstrom, the co-creator of PC title Hotline Miami, offered help and advice to those who had downloaded the game via The Pirate Bay.


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Links to Norman County Information
Norman County was organized on February 17, 1881, from a part of Polk County, which in turn had been a part of Pembina County. The name was chosen because of the great number of Norwegian immigrants who settled in the county. Norman County is located in
the Red River Valley of Minnesota, one of the great farming regions of the
world. To the east it is bounded by Mahnomen County, to the south by Clay
County, and to the north by Polk County. The western boundary is formed by the
Red River of the North and North Dakota. The county is made up of twenty-four
Check out the
of the county as it looked in 1895. The goal of this website is to be of assistance to those people seeking information regarding people who lived in Norman County. This goal can only be accomplished with the help of fellow genealogists who share information that will be helpful to others as they search for their Norman roots. Please contact the County Coordinator if you have information to share.
USGenWeb Project This site is maintained by Colleen Goltz with the dedication and assistance of the Norman County Historical and Genealogy Society. For any questions regarding this site please contact the State Coordintor @ Colleen Goltz/2014. |


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Aberdeen defender Andrew Considine is suspended for Saturday's Scottish Premiership visit of Dundee United after being sent off in the midweek draw with Ross County.
Peter Pawlett could return from a hip problem after training with the squad on Thursday but fellow midfielder Jonny Hayes (collarbone) is still out.
Clark Robertson continued his comeback from knee surgery by playing 60 minutes for the under-20s in midweek but the game is likely to come too soon for the defender.
Dundee United pair Nadir Ciftci and Andrew Robertson are suspended for the trip north.
On-loan Newcastle defender Curtis Good is still sidelined for United with hip injury.
Manager Jackie McNamara otherwise has a full United squad for the Pittodrie visit.


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Trego sophomore qualifies for state tennis
Published on -5/5/2013, 8:23 PM
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By The Hays Daily News
WaKeeney-Trego Community sophomore Isaiah Fabrizius qualified for the Class 3-2-1A state championship for the second straight year. He took sixth in singles at the WaKeeney regional. Fabrizius is 12-15 and scored the only two points for the Golden Eagles. WaKeeney finished seventh in the eight-team regional. Russell was eighth with one point. Claflin-Central Plains won with 23 points.
Fabrizius defeated Ellsworth's Aiden Mendez 6-0, 6-1, then lost to Hoisington's Ryan Smith 6-2, 6-1. Fabrizius defeated Cimarron's Caleb Neuschafer 6-2, 6-4 to earn a spot in the top six. Then, he lost to Ellsworth's Isaac Herzog 4-6, 6-3, 6-2 in the fifth-place match.


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Hell Horror
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Kris Lemche Cast as Lead in Tales From the Darkside Pilot Episode
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'Independence Day 2' Sequel Casts Jeff Goldblum, Jessie Usher, Liam Hemsworth and Release Date
So just like that, Independence Day 2 (2016) casts Jeff Goldblum, Jessie Usher and Liam Hemsworth for the Independence Day Sequel. Director Roland Emmerich seems to be setting the gears in motion fast trying to make the June 24, 2015 release date for Independence Day 2. This is the sequel to the Summer 1996 hit…
First Still and Poster for the Martyrs Remake
The Martyrs Remake is being directed by The Goetz Brothers and today we have the first movie still and poster. Starring in the remake are Bailey Noble, Troian Bellisario, Kate Burton and Blake Robbins. This remake is based on the hit Martyrs (2008) directed by Pascal Laugier. Did you see the original and what do…
Rob Kazinsky Cast as Lead in Fox's Frankenstein TV Series
Rob Kazinsky has been cast as the lead in the new reimagining of Fox's Frankenstein TV Series. Kazinsky will play the new version of the Frankenstein monster named Ray Pritchard. Also cast is Adhir Kalyan as Otto Goodwin, described as "one of Ray's creators, the quiet and brilliant Internet billionaire." What do you think so…
El Rey's From Dusk Till Dawn Season 2 Started Production Today
El Rey's From Dusk Till Dawn Season 2 began production today for the next 10 episode continuation into the vampire TV series. Robert Rodriguez will direct the first episode of season 2. I want to see more into the mythos this time around. The photo below features Eiza Gonzalez (Santanico Pandemonium), Robert Rodriguez (Creator, Director…
Scream Factory's 'Mad Max' Collector's Edition Blu-ray Release Details
Have you been waiting for the Collector's Edition of Mad Max (1979), Scream Factory is delivering. The extra bonus features include new interviews with Mel Gibson and audio commentary among others listed in full detail below. Director George Miller made a classic with Mad Max and the stars who include Mel Gibson, Joanne Samuel and…
New Horror Short - Killer Kart
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CW's iZombie Season 1 Third Poster Released
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News Release 605
Higginsville will receive Land and Water Conservation Fund grant for park improvements
Volume 38-605 (For Immediate Release)
For more information:
JEFFERSON CITY, MO. OCT. 18, 2010 -- The Missouri Department of Natural Resources today announced that Higginsville has been approved by the National Park Service for a $46,000 grant to renovate the softball field and make the parking areas accessible at Fairground Park.
"This is a great opportunity for Higginsville. Outdoor recreation is a great form of healthy fun and also brings the community together," said Bill Bryan, director of the department's Division of State Parks.
The grant is one of 11 FY 2010 Land and Water Conservation Fund grants for Missouri recommended to the National Park Service by the State Inter-Agency Council for Outdoor Recreation. The LWCF program provides federal grants to assist with park and recreation needs. Land developed with these funds is protected in perpetuity by the National Park Service and must be used for outdoor recreation.
The grants are available to all local governments and public school districts and can be used for development or renovation of outdoor recreation facilities or acquisition of park land. All projects require a 55 percent match. In Missouri, the program is administered by the Department of Natural Resources' Division of State Parks.
For more information on the Land and Water Conservation Fund grants, contact the Division of State Parks at 573-751-5374 or visit the website at mostateparks.com/grantinfo.htm.


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bioTheranostics To Present Data onCancerTYPE ID and Breast Cancer Index at 2013 ASCO Annual Meeting
Data from 11 studies demonstrate the clinical utility and cost-effectiveness of company's molecular tests for cancer of unknown primary and breast cancer recurrence
FOR IMMEDIATE RELEASE…May 29, 2013…SAN DIEGO…bioTheranostics, Inc., a leading provider of molecular diagnostic solutions for cancer, today announced that 11 data presentations will be released during the American Society of Clinical Oncology (ASCO) annual meeting May 31–June 4, 2013, in Chicago. The studies highlight the clinical utility of the company's CancerTYPE ID® assay and Breast Cancer IndexSM (BCI), with results supporting the role of these molecular tests in individualized treatment programs for cancer patients.
bioTheranostics also will host an Industry Expert Theater educational presentation titled, "Demanding Certainty in Metastatic Cancer Diagnosis: The Clinical Impact of
CancerTYPE ID®," June 2, 2013, at 11:30 a.m. The company's products will be demonstrated at booth #23041.
"These studies are part of a large and growing body of clinical evidence demonstrating the positive impact our CancerTYPE ID and Breast Cancer Index molecular tests have on the management of cancer patients," said Richard Ding, president and CEO of bioTheranostics. "The data provide key insights into the value of our molecular tests in influencing clinical decision making and impacting patient outcomes and healthcare costs, and we look forward to sharing and discussing the results during the 2013 ASCO meeting."
The studies were conducted by researchers at leading institutions, including Linköping University (Sweden); Louisiana State University Health Sciences Center; Massachusetts General Hospital; Sarah Cannon Research Institute; University of California, San Francisco, School of Medicine; University of Kentucky; University of Pittsburgh Medical Center; and the University of Texas MD Anderson Cancer Center.
CancerTYPE ID Posters & Abstracts
Breast Cancer Index Poster & Abstract
Abstracts for the 11 studies concerning bioTheranostics' molecular tests can be accessed on the ASCO website.
About bioTheranostics
bioTheranostics is the leading solution provider for metastatic cancer management, leveraging its unique expertise in expression profiling to develop a growing array of molecular diagnostic tests for cancer patients. The company operates a CLIA-certified, CAP-accredited diagnostic laboratory to perform its proprietary tests: the CancerTYPE ID® molecular classification test; PRÉCIS® Precision Medicine, which includes biomarker profiles for non-small cell lung and colorectal cancers, and other cancers; and
Breast Cancer IndexSM, which quantifies risk of recurrence of estrogen receptor-positive, lymph node-negative breast cancer. bioTheranostics, a bioMérieux company, is based in San Diego. For more information, visit www.biotheranostics.com.