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Sleeps | 8 |
Bedrooms | 3 |
Bathrooms | 2 |
Property type | house |
Minimum Stay | 4 - 7 nights |
This home is located close to Disney, Orlando/Kissimmee and the Central Florida attractions. Come and enjoy the freedom of a home rental rather than the restrictions of a hotel. This property is on an oversized lot, in a residential vacation rental area. The home has an alarm system if you wish to use it and the doors out to the pool all have pool alarms. A book is supplied in the home to give you information on the area, access routes to the parks and grocery/shopping places. Publix (grocery) is 5 mins away along with fast food and dining in that plaza, or use the 24 hour walmart - two to choose from less than 10 mins from the home. Perhaps you want to shop the Malls/discount outlets or flea Markets - there is a lot to choose from!. The 192 resort area has an ambundance of fastfood, buffet style, family and fine dining. Out back steak house, Red lobster, Italien cusine, Chineese restaurants and buffet, or perhaps choose one of the many hotel restaurants - perhaps a character breakfast!
NEW guest service - We HAVE FREE LONG DISTANCE AND FREE INTERNATIONAL CALLS -Includes Canada and UK! Plus FREE WIRELSS INTERNET for the duration of your stay.
It is a short drive( Direction in the book in the home) to all the Disney Parks - 15/20 mins (Magic Kingdom,Epcot, Hollywood Studios, Animal Kingdom, Blizzard Beach) or visit Seaworld, Aquatica, Universal Studios, Islands of Adventue, Wet and Wild, or one of the many Dinner shows, of the famous Cirque Du Soleil. There are many other activities to do not forgetting mini golf, movie theatres( At the Loop and Pleasure Island), Downtown Disney, The Orlando Science Center, and Orlando art exhibts/Museums - see a show/play or concert.
An often overlooked area of Orlando is the oppotunities to watch wildlife - Gators at Gatorland, or bird watching at the Nature conservancy and lake front. Get first hand knowledge with Kissimmee Valley Audubon on their filed trips or monthly meeting - free. Walk/hike many of the nature trails in the area - the enviromental center is close by or visit the Birds of prey/refuge center in Maitland. There is always horse back riding at the nearby stables, or take an airboat ride, Kayak from many boat ramps or on shingle creek which leads to the Everglades. Forever Florida is a great family day out and has a Zip cord run plus a Swamp buggy tour- see the real Florida. Perhaps do some local fishing or hire a guide. We have info and brochures to help you make your plans.
This house is professionally managed, by a company close to the property, and maintained including pest control, to a high standard. The lawn and pool are looked after by liscensed companies. We have received a high number of repeat or referal bookings. Our rentals are based on satisfied clients. Call or e-mail Michelle to ask any questions you may have, or make a reservation. We are members of the Kissimmee St. Cloud Visitors Bureau.
Payment: $100 will confirm your reservation and put the house in your name for your dates. The remaining balance, plus $200 damage deposit (refunded 7/10 days after your stay), Plus a $25 booking fee is due 60 days prior to arrival. We acept Visa, Master Card Amex, USA Dollars or Sterling. we have a secure link for payment by credit card or e-check.
We have a UK address that Sterling checks can be mailed to - to accomodate the many reservations we take from the UK market, or online bank transfer to Barclays .
Keywords: Private Home
Hi Michelle,
Herewith I'd like to thank you for the wonderful house in Kissimmee.
Everything was good on it and we enjoyed our stay. I'm sure that we
will use one of you houses again in the future!
Once again many thanks for your service.
Kind regards,
Andy Heideman
I loved the location of this home close enough to visit all the theme parks but far away from all the hassle. I was not surrounded by the over tired parents or children you have when you stay at vacation resort. Check in was so easy just followed the instructions emailed to us opened up the house pulled into the garage and unpacked, none of the hassles of checking in at a hotel and lugging your bags behind you. Also had 2 living rooms 2 dining area, 3 bedrooms and a private pool for a same price as 1 room at a resort. Almost all the residences are perm residences and the few we met were very kind giving us valuable info like the best places to shop, eat and check out. It was so nice just to get up in the morning and have coffee around the pool before we started our day of site seeing. The master bedroom was huge with a wonderful with an on suite that had a door that lead right out to the pool. In fact both bathrooms had doors that lead you right out to the pool which made changing so much easier. I know it sounds funny but the thing I liked best was the washer and drier in the garage. Renting the house even made coming home easier as I did not have to come home to unpacking and loads and load of laundry. The owner thought of everything for families with babies to families with teens. It was an excellent house for an excellent price and I would recommend it to anyone.
This home is very spacious. The layout is great. Very comfortable and convenient. It's location is in a quiet and pleasant area but not too far from many attractions and conveniences. I love the fact that there are doors from each bathroom which access the pool area and also that you can come into the house from the pool via the French door but you don't come directly into the living room as I've seen in other homes. The home is well maintained in all areas. The management is excellent. If you have questions or need anything they are quick to respond and assist. I will definitely be booking a stay here for next year.
We were very please with how clean the house was when we arrived. The layout of the house was good including enough seating for 6 - 8 people. It drives me crazy when I look for places that say sleep 6 to 8 and the living room/family room has seating for 5 which puts someone in a dinning room chair or on the floor. The master bedroom was huge along with the master bath. The other two rooms were average size but well furnished. Actually I would say that the home was also comfortably furnished and nothing was heavily worn. For those that have to have a TV in the bedroom the master bedroom is the only one that had a TV. Good for me since I stayed in the master bedroom and my husband can't unwind without 10 minutes of TV of some kind. But there are 2 other TVs in the house. There were plenty of towels, linens and dishes for everyone. We only made a couple of eggs and bagels so I don't recall 100% all the cooking utensils, but everything we needed and looked for was there. We did not use the pool but it was very clean and warm when we stuck our foot in it. We did go out in the pool area one morning and sit. Again enough seating for all the people with us. The alarm on the door to the pool surprised us, quite loud, but fully understand why. The location was very good but you do need a car. We were away from the crowds in a nice development, right off the main road to get there, but only a 10 minute drive to Irlo Bronson Hwy (I think that was the name) to tons of restaurants, souvenir shops and grocery stores. There was also a grocery store about 5 minutes away from the house, but our GPS took us the scenic route on the way there which took us 10 minutes. It was about 20 minutes from Disney with traffic and almost 30 minutes with traffic to Universal. I think Universal took longer than expected because we were driving during morning rush hour. Michele the property manger was quick to respond and helped us with information in the area.
This is a beautiful home, we felt very comfortable and safe. It was convenient for the places we went. The neighbors were friendly and the neighborhood was nice and quiet after a long day filled with fun. We would definitely rent this again.
We enjoyed our stay at this very spacious and well maintained home. Heated pool was awesome! Very close to the parks and shopping. House looks even better in person. We didn't want to leave! Thanks for a great stay!
I would recommend this property! We had a great time. The rental process was easy and Behlor Realty was very accommodating. The house was very clean and had everything we needed. The pool and lanai were very relaxing. Quiet neighborhood. While it seemed a bit off the beaten path, once we got familiar shopping, etc. were easy to get to. We enjoyed being in a quiet neighborhood and out of the busier areas.
All of the attractions - Disney, Magic Kingdom, Hollywood Studios, Epcot, Animal Kingdom, Blizzard Beach, Thphoon Lagoon,Universal Studios and Islands of Adventure, Sea world, Disovery Cove, Aquatica, 15/20 mins drive. Cocoa Beach 1 hours drive & Clearwater Beach 2 hour drive, with Bush Gardens 1 hour from the hosue . If environmentally minded perhaps visit the Disney Wilderness Reserve( run by the nature conservancy), Or shingle creek, the enviromental Center, Or many Birding sites and Kayaking
Rate Period | Nightly | Weekend Night | Weekly | Monthly | Event | ||||
Jan 3 2015 -
Mar 20 2015
4 night minimum stay
Easter period
Mar 21 2015 -
Apr 10 2015
7 night minimum stay
Mid season
Apr 11 2015 -
Jun 5 2015
4 night minimum stay
Jun 6 2015 -
Sep 4 2015
7 night minimum stay
Sep 5 2015 -
Dec 18 2015
4 night minimum stay
Christmas Period
Dec 19 2015 -
Jan 8 2016
7 night minimum stay
Jan 9 2016 -
Mar 11 2016
4 night minimum stay
Easter period
Mar 12 2016 -
Apr 8 2016
7 night minimum stay
Apr 9 2016 -
Jun 3 2016
4 night minimum stay
Jun 4 2016 -
Sep 2 2016
7 night minimum stay
Sep 3 2016 -
Dec 16 2016
4 night minimum stay
Dec 17 2016 -
Jan 6 2017
7 night minimum stay
Refundable damage deposit | $200 |
Booking fee | $25 |
Tax Rate | 13.0% |
Notes |
Visa/Mastercard/Discover - we have a secure link for credit card payments, or e-checks (free), thru Homeaway or VRBO. Please e-mail Michelle, from this site, or firstname.lastname@example.com. For stays 5 nights or less for an accurate quote.
Pool heat if needed $105 per week |
Payment is usually accepted in the quoted currency (USD) unless the currency and the amount is specifically agreed in advance with the owner / advertiser.


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33 images for bjp youth wing president | ||||
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subset: commoncrawl


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Fergie's Legs Are Her Lucky Spot — Do You Have One?
Fergie's Legs Are Her Lucky Spot — Do You Have One?
After putting on 17 pounds for the movie Nine, Fergie learned it takes a lot longer to lose weight than it does to gain. Let's just say she's "2000-and-late" when it comes to learning this weighty reality (can you tell I've added the Black Eyed Peas' Boom Boom Pow to my workout mix?).
The extra poundage is nowhere to be seen on Fergie's skin-baring Allure cover shot, and the singer credits working out with her hot husband's trainer for getting her super-toned body back. In her interview with the magazine for its May issue, Fergie said,"If I don't do sit-ups, my stomach sticks out. Legs are easy for me. That's my lucky spot."
Well, it's a little reassuring to know that taut tummy doesn't come without hard work. Do you have one area that you can count on to look good without much effort, like Fergie and her stems?
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Middle EastAl Jazeera staff face Egypt verdict next week Court adjourns 12th session of trial of journalists, who have now spent 170 days in jail accused of aiding "terrorists|. 16 Jun 2014 17:08 GMT | Middle East, Egypt, #FreeAJStaff The trial, which began on February 20, has triggered international outrage [AP]An Egyptian court has said it will deliver its verdict next week on three Al Jazeera journalists accused of aiding the blacklisted Muslim Brotherhood and reporting "false news". Judge Mohamed Nagui Shehata on Monday told the 12th session of the trial in Cairo that he had reserved June 23 to pronounce the verdict against Baher Mohamed, Peter Greste and Mohamed Fahmy. The three journalists have now been held for 170 days on charges that Al Jazeera strongly denies. Egyptian prosecutors have demanded the maximum penalty of 15-25 years in jail for all defendants, but defence lawyers and relatives expect the accused to be acquitted. The prosecution has submitted as evidence items including a pop video by Gotye, a faked photograph, a BBC podcast and videos made outside of Egypt about an animal hospital. Live Box 20141810351259628 The trial, which began on February 20, has triggered international outrage amid fears of growing media restrictions in Egypt. Of those on trial, 16 are Egyptians charged with joining the Brotherhood, which was designated a "terrorist" organisation in December following the army's overthrow of Islamist president Mohamed Morsi in July. "Today was the final summation by the defence, again the weaknesses of the prosecution case has been exposed. On the balance of arguments, Al Jazeera hopes the judge will take into consideration the facts presented to him and acquit Peter, Baher and Mohammed of any wrong doing," said Al Jazeera's spokesman Osama Saeed. "On June 23, the entire world will be watching Egypt to see whether they uphold the values of press freedom." Nine of the 20 defendants are in custody, with the rest being tried in absentia. During the hearings Greste, a Peabody Award-winning journalist, and his co-defendants have denounced the trial as "unfair and political", charging that the evidence against them had been "fabricated". Some of their co-defendants have claimed to have been tortured in prison. "For six months now we have been treated like terrorists with weapons," Fahmy told the court on Monday. "A television channel cannot destroy a country," said Fahmy. The authorities have previously said that the accused were operating in Egypt without any valid media accreditation. Al Jazeera stands by its reporting from Egypt. Click here to watch our reports from July to December 2013. Source: Al Jazeera
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Jane Eyre Trailer: Hello, Mr. Rochester!
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Pochomil Near The Ocean Vacation Rentals(8)
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Recent Pochomil Reviews
Great place to get away from it all
We have just returned from a great stay in Pochomil. The house was perfect for our young family (2.5 year old and 7 month old). The beach was a stones throw away, and deserted. It was so great to disconnect for a week, spend time at the house and enjoy the simple things. Highly suggest a trip or 2 to the fish market. Also the housekeeper and cook is fantastic. She made our vacation a true vacation...never having to worry about meals or spending nap time prepping dinner! Fresh mangos from the tree by the pool were an extra treat!
Awesome Vacation As suncion
Awesome Vacations.
Definitely I highly recoment Casa Marbella(pochomil beach)
We staying in this property on December 26 thru 28. My family and I have a great time, this house is peaceful, relaxing views ectacular and the staff is extremely nice and helpful and Maria is a wonderful cook.
Marbella house was by far our best experience.
Thank you Carmen for allowing us to rent your beautiful house.
Just a Wonderful Vacations
My brother and I, rent this house, its just great. clean, and the people working there, just amaze, they keep everything clean and we cant ask for more. thanks its was a very pleasant experience.


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10/07/2009 08:42
nobel annoucement 248 88 ap. (photo credit:AP)
Prof. Ada Yonath of the Weizmann Institute of Science - whose highly abstruse field and targets were regarded with skepticism by colleagues and who was treated like "the village fool" for years - has been awarded the 2009 Nobel Prize in Chemistry for her four decades of research on protein "factories" in cells. Her dedicated work has led to the current struggle against antibiotic-resistant bacteria and many other applications. Yonath is the world's first woman to become a chemistry laureate since 1964, and only the fourth in history. Her prize will be Israel's ninth Nobel and its second in chemistry, and the Rehovot institute's first. The ceremony will be held in Stockholm on December 10. Continuing a message expressed numerous times by Prof. Aaron Ciechanover after he won the 2004 Nobel in Chemistry with his mentor, Prof. Avram Hershko, Yonath warned on Wednesday that inadequate government funding available for aspiring Israeli scientists would make it far more difficult for younger researchers to earn Nobel Prizes in the future. "Those who win the prize now do so because of what has happened before, not because of what is happening now," she said. However, she added that the world would soon be hearing about a promising new generation of Israeli scientists. The Royal Swedish Academy of Science announced two other winners to share the prize - American scientists Venkatraman Ramakrishnan and Thomas Steitz, for their work on mapping ribosomes at the atomic level. The three will share the $1.4 million (10 million Swedish kroner) in prize money. All three chemistry laureates generated three-dimensional models that show how different antibiotics bind to ribosomes, but Yonath's work was the pioneering "mother" of the field. All three have used a method called X-ray crystallography to map the position for each and every one of the hundreds of thousands of atoms that make up ribosomes, the academy stated. Appearing shell-shocked, with her famous mane of curly grey hair looking slightly wild, Yonath told a hastily arranged Wednesday press conference at the institute - which like all other universities is on Succot vacation - that she suspected reports of her winning the Nobel prize were an elaborate hoax until she received the official phone call notifying her of the award. "When I saw the +46 Swedish country code on my phone screen, I thought, they're really taking this prank far," she said. "I'm happy, and shocked. I can't say exactly how I felt when I heard." "Celebrities are more important than professors - everybody knows that," she added. Asked by Channel 2 TV what she would be doing first thing Thursday, the down-to-earth new Nobel laureate replied that she had to take her car for its annual licensing test. "Oh, and I first have to wash it." Yonath has one daughter, Dr. Hagith Yonath, a senior internal medicine specialist in Sheba Medical Center at Tel Hashomer, and one teenage granddaughter, Noa. "I am very proud of my mother," Hagith said with emotion. "This is a prize that has arrived after many years of hard work. We always believed in what she was doing in her special way." Struggling with the intense media spotlight cast upon her, Yonath told dozens of reporters and photographers surrounding her, "What I went through to get into this room is almost as difficult as my research. I have almost lost the ability to speak." Yonath said she was working away in her laboratory when she got the news and that she continued working after taking the call - until she was forced to stop by colleagues and friends. Addressing younger Israeli scientists, Yonath said curiosity was the key to scientific progress. "If one has curiosity, then one stands the chance of attain a high level of scientific inquiry." Israeli scientific achievement has gone up several notches since "the days when I finished my doctorate," Yonath added. Soon after the award was announced, President Shimon Peres called Yonath to congratulate her. "We are proud of you, it's hard to describe just how proud. One must remember that modern economies are not just global, but also individualistic - as a single person with creativity and innovation can be the basis for whole industries, and Israel excels in human talent." Prime Minister Binyamin Netanyahu followed by telling her: "I feel deeply proud. The Nobel Prize is humanity's real Olympics [medal]. Such contributions to science and academia have characterized the Jewish nation and the State of Israel for many years," he added. Science and Technology Minister Daniel Herschkowitz, a leading mathematician who previously taught at the Technion-Israel Institute of Technology, told The Jerusalem Post that he hadn't been informed Yonath was a candidate but knows her personally and has long been impressed. "It is true for all laureates that the prize is given decades after their achievement. It takes much time from the moment of the discovery until it is appreciated," he said. He added that he would not predict whether young Israeli scientists starved for research funds and positions - while others are successfully lured to remain abroad - would win Nobel Prizes in the future. "But I definitely agree that unfortunately, Israel is not investing enough in science, and we must do more," the minister said. The Weizmann Institute was delighted. "The Nobel Prize committee has recognized the significance of Prof. Ada Yonath's scientific research and awarded her this important prize. Her research is driven by curiosity and ambition to better understand the world and our place within it. This research aims high - to understand one of the most complicated 'machines' of the biological system," a statement it issued said. The institute, which was taken by surprise even though Yonath has been regarded as a serious Nobel candidate for years, said that her "basic research - which began in the attempt to understand one of the principles of nature - eventually led to the understanding of how a number of antibiotics function, something that is likely to aid in the development of more advanced and effective antibiotics. It is hoped that her discovery will also help in the struggle against antibiotic-resistant bacteria, a problem recognized as one of the most central medical challenges of the 21st century." "I was simply in tears; what an achievement," enthused Prof. Rivka Carmi, president of Beersheba's Ben-Gurion University of the Negev who is a leading geneticist and pediatrician in her own right, as well as Israel's first female university president. "It is about Israel and the world and women - but it is above all about Ada with her incredible science, vision, stamina, determination and courage. And it is to me about closing a small circle: Note that Rosalind Franklin [the woman who was actively involved in describing the double-helix structure of DNA but did not receive a Nobel with Profs. James D. Watson and Francis Crick] was also a crystallographer." Prof. Karen Avraham, a leading molecular geneticist at Tel Aviv University's Sackler School of medicine and chairman of its search committee for new faculty, told the Post that Yonath "made her discoveries at a time of great challenges - at a time when our country was young - and while science was blossoming, resources were scarce. She worked in an area of basic research; the applications of this work were unknown then. Now we know that her work, and that of her co-winners, has been a major factor in our understanding how antibiotics work, which is undoubtedly one of the most important medical achievements in the past century." She was greatly influenced by another woman scientist, Marie Curie, added Avraham. "Young women scientists need role models, and Ada has been a model for many of us in Israel and beyond. She has shown us how hard work and intellect can lead to success. Ada's discovery was and is brilliant - a timeless event, since while at the time it was made it was ground-breaking, the work continues to have far-reaching implications for human health and medicine." Prof. Mary-Claire King, the highly respected geneticist at the University of Washington School of Medicine who is widely praised for her discovery of the BRCA1 gene responsible for many breast and ovarian cancers, e-mailed the Post to say that Yonath - her good friend - solved the structure of the ribosome down to the level of each of its atoms. "The understanding of the ribosome's function was revealed by its structure. Just as for DNA, structure revealed function. I particularly admire Ada's evolutionary perspective on the ribosome, these elegant structures over the entire course of their very long history, from bacteria to mammals. Her evolutionary perspective led, I believe, to the critical link of bacterial ribosomes as a target for antibiotic therapy." Prof. Ehud Razin, president of the Israel Chemistry Society, noted that chemistry and computer science have proven to be the country's two leading fields. Chemicals, he said, constituted a quarter of its exports. Of nine state presidents, two - Chaim Weizmann and Ephraim Katzir - had been chemists, he added. Although Yonath has accumulated prizes - more than 30 of them - like other women collect jewelry, she is very modest and unassuming. Among her most important previous awards were the Israel Prize, the Wolf Foundation Prize and the Technion's Harvey Prize (both of which often preceded the Nobel), She installed the medallions, statues and parchment scrolls on a wall near her office "to bring joy to Helen Kimmelman, my New York benefactor who has invested in my research since 1988." She recalled in a Post interview last year that "I was the village fool for many years. It didn't bother me at all. I had doubts of course. At first, I wasn't sure that it would work. I had a lot of luck. For quite a while, I didn't receive a higher academic status. I didn't feel any discrimination against me as a woman scientist, but I hadn't produced a lot of science journal articles. The Weizmann Institute showed me respect and didn't require many administrative tasks, so I was quite independent. I did what I wanted." She was born in 1939 in Jerusalem's Geula quarter to Zionist parents born in Poland. Her father was a rabbi who didn't know much about science and ran a grocery store in the neighborhood with her mother's help, she said. She studied at the state elementary school in the capital's Beit Hakerem neighborhood. Yonath acknowledged her humble beginnings. "My neighborhood didn't really encourage women, though it didn't prevent women from progressing either," she said. "My kindergarten teacher encouarged me to learn, as did my school headmaster, who gave me a grant to study," she added. Interested in science at an early age, Yonath conducted experiments on their apartment balcony. "Once, when I tried to calculate the height of the balcony, I broke my arm. Another time, I wanted to see if water moves faster than kerosene. When my father came out to smoke, a fire broke out." But her father died at 42, when she was only 10; her widowed mother, 38, had difficulties trying to run the grocery alone and moved with her and her sister to Tel Aviv to become a low-paid Treasury clerk. After military service, Yonath returned to Jerusalem to earn her bachelor's degree in chemistry and master's degree in biophysics at the Hebrew University. She earned her Ph.D. at the Weizmann Institute and accepted postdoctoral positions at the Massachusetts Institute of Technology and Carnegie Mellon University in the US. In 1970, she established at Weizmann what was for nearly a decade Israel's only protein crystallography laboratory. After returning from a sabbatical year at the University of Chicago, she also headed for 17 years a research unit at the famed Max Planck Research Unit in Hamburg, Germany, in parallel to her research activities at Weizmann. The target of Yonath's research for two decades has been ribosomes, which assemble proteins according to the genetic code, in a process called translation. Ribosomes build proteins from the genetic instructions held within messenger RNA. "I wanted to reveal how genetic code is translated into protein. I knew a great application could be for antibiotics, since half of the useful ones target the ribosomes, but I didn't believe I could contribute to it. It was like the next Mount Everest to conquer. It was my dream to contribute something to humanity," she recalled. Her work took a big step forward in 1987, when she and her team developed the cryo technique. Her methodology contributed not only to ribosome research but also to the entire field of structural biology. Before then, a few hundred protein structures had been determined. Since 2000, 27,000 have been added. Yonath devoted herself to discovering the structure of the ribosomal machinery of peptide-bond formation and was the first in the world to pioneer ribosomal crystallography, against all odds and singlehandedly, when others couldn't even conceive its possibility. By pushing crystallography to its limits, she demonstrated the feasibility of this technique, thus inspiring prominent groups to repeat her experiments. By determining - in an incredibly short time - the structures of over a dozen different complexes of antibiotics, she revealed the ribosome-antibiotics binding sites on the molecular level and provided insight into antibiotics selectivity. Only on Tuesday, Israeli academics were disappointed when leading Tel Aviv University physicist Prof. Yakir Aharonov was not chosen for that Nobel Prize, even though he was highly rated in the competition. Yonath's prize on Wednesday made up for that disappointment.
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OK, so the "robbed in Italy" post got me to thinking, it's been almost a decade since I've travelled to Paris, and this time we'll have two children with us. That's almost a guarantee of being a bigger potential target. Not that I'm paranoid or worried, but just that it's probably wise to know what some of the latest scams and tricks are to be mindful of. Maybe which neighborhoods or attractions to be wary of, etc. Lingo or buzzwords or behaviors to be wary of.
Obviously one shouldn't stand around Gare Du Nord looking lost or distracted with an ipad dangling haphazardly out of an open handbag. (I've seen large groups of tourists looking like this in almost every European train station I've ever arrived in.)
But I do think it's helpful and important to know what to look for these days... either in general and in Paris specifically.
Back in the good ol' days of the nineties, back before iPhones and iPads and wifi, back when they had money called Lire and Francs, back when passports were tucked deep into money belts that fit comfortably under my pre-baby jeans, back when I could pack everything I needed into a carryon... oh wait... got lost reminiscing.
Can't wait to go back, scams and hustles and pickpockets be damned!
What are the latest scams & hustles in Parisian travel?
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There has been much discussion on Fodor's Forum about cell phones being stolen from tourists sitting at cafes. We sat in many cafes and were careful with out phones and did not witness any other phones being stolen. In fact many locals would lay their phones on the table whole eating/chatting.
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The usual scams are the gold ring scam, the string bracelet guys, the petition girls, pickpocketing, leaving a cell phone or wallet on an outdoor cafe table and having it stolen, people who offer to help you buy metro tickets from the machines and people who get stuck in front of you in a metro turnstile while someone behind you bumps into you and pickpockets your valuables. Other than that you have nothing to worry about.
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Learn to ignore people who approach you. Teach your children that you may act differently to strangers in Paris. I explained to my 11 yr old daughter about a few scams, the ring and petition girls and explained that mommmy may appear to be rude ignoring people and why, see at home we do not need to ignore people so I knew she would find it odd. Well sure enough after a few days in Paris a lady tried the ring scam on us and my daughter burst out laughing at ladys "madam" and said , "oh look its the ring scam".. the lady immediatly and sheepishly walked on as we did also( we did not stop for whole spiel) .
Most of the scams are not new at all, being going on for years and years.. lol
You are correct about all our pocket electronics,leave nothing on cafe table , waiter told me to put my Kobe ereader on my lap when I set it on table to go in my purse for a minute.. so yes, do watch that. -
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I am always suspicious of ever new ways to steal cash from ATM machines. I always try to use machines located in the public places someone else has successfully obtained cash ahead of me. If one person walks away empty handed, I examine the machine super carefully and if I thought the person was clueless. If more than one person walks away empty handed, I would stay away from that machine.
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I never even think about scams and hustles or worry about them because I don't have anything to do with strangers on the street or in the metro, etc. trying to do weird things, asking me to participate in any stupid activity (whether signing a petition, asking if anyone speaks English, on and on) nor do I talk to them nor engage with them, nor will I allow them to invade my personal space nor touch me in any way (some of them do, they'll come up to you and take your hands, put things in it, etc, I would never allow someone to do that). I would never even talk to some person walking around picking up things on the ground and approaching strangers, which is what you'd have to do to be fooled by the stupid ring scam.
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oh, since you are concerned about your children, you should have taught them not to interact with strangers already, on the street, in stores, etc. There is no magic lingo or buzzwords, they just shouldn't do that anyway, the idea that you would allow your children to talk to or take things from strangers on the street if they don't say some magic buzzword isn't what I would call being cautious in any city.
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Wow, reading what Christina had to say made me a bit sad that the world has come to this. I think that I would have missed out on many lovely interactions with strangers if I had adhered so strictly to a "no talking to strangers" rule. Of course you need to be cautious and aware of yourself and your possessions, but I must admit that I sometines talk to strangers, in Paris and elsewhere. Last time I was in Paris, I ignored the woman who approached me with the ring, but when I saw a young girl weeping by herself outside a restaurant, I asked her if she needed help. She told me that she just had a phonecall that her father had died. Having lost my own dad months earlier, I offered what words of comfort I could and stayed for a while till her friend arrived. After our brief conversation she thanked me for stopping to talk to her. I should probably have looked to see if she had an accomplice waiting nearby to relieve me of my valuables, but sometimes you just go with your gut. I have also been the recipient of unexpected kindness or heard interesting stories from strangers on many occasions. I have asked strangers for directions in European cities and had them turn and lead me to to the place I was asking for because it was easier than explaining. Of course, I've also encountered unfriendly people - I'm pretty sure I must have run into Christina once or twice.(insert smiley face!)
I know this is about looking out for scams, as we absolutely should, but I don't think we need to raise rude, paranoid children in order to do that. (Not talking about your daughter, Justine, her response was perfect in that context.) -
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I learned the ring scam is alive and well as I was approached twice within ten minutes in the area around the Pont Solferino that connects the Tuilleries and D'Orsay. Another Paris GTG attendee was approached on the bridge as well. I laughed when it happened the second time and in hindsight wished I'd snapped a photo.
Ann Marie -
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I was amused last night watching a French film,
After Autumn, Winter. An american, his first night in Paris falls for the ring scam (you only know this later)
One night walking about he sees a gypsy lady pulling the scam on a couple and runs up to them yelling no no it's a scam.
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I am way overdue to write this review. Since I stayed at Ca' della Corte, I have stayed at another B&B in Venice and now have something to compare. Ca' della Corte is definitely my top choice for my next visit to Venice. I actually preferred the location tremendously. You can get there without having to get on the vaporetto... More
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March 4, 2015
Cowen to hold a conference
35th Annual Health Care Conference is being held in Boston on March 2-4 with webcasted company presentations to begin on March 4 at 8 am; not all company presentations may be webcasted.
Webcast Link
March 3, 2015
GlaxoSmithKline looking for buyers for Nicotinell business, AFR reports
GlaxoSmithKline is looking for a buyer for its Australian nicotine chewing gum business Nicotinell, according to the Australian Financial Review.
Reference Link
March 2, 2015
Isis Pharmaceuticals earns $15M from GlaxoSmithKline for advancing ISIS-TTR Rx
Isis Pharmaceuticals (ISIS) announced that it has earned a $15M milestone payment from GSK (GSK) related to advancing the Phase 2/3 study of ISIS-TTRRx in patients with familial amyloid polyneuropathy. ISIS-TTRRx is an antisense drug Isis is developing with GSK for the treatment of transthyretin amyloidosis, a severe and rare genetic disease characterized by progressive dysfunction of peripheral nerve and/or heart tissues. Including this milestone payment, Isis has generated $60 million in upfront and milestone payments for advancing ISIS-TTRRx. In addition, if GSK elects to exercise its option to exclusively license ISIS-TTRRx, Isis is eligible to receive a license fee, regulatory and sales milestone payments and double-digit royalties on sales of ISIS-TTRRx.
February 25, 2015
GlaxoSmithKline sees Novartis transaction closing next week
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GlaxoSmithKline announces return of alli to retail stores
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February 23, 2015
RBS could name Howard Davies as chairman this week, FT reports
Royal Bank of Scotland (RBS) could name Howard Davies as its chairman as early as Thursday, when the bank reports its full-year results, the Financial Times reports. Davies is currently chairman of insurance business Phoenix Group and chairs Morgan Stanley's (MS) risk committee. Current RBS Chairman Philip Hampton is set to become GlaxoSmithKline's (GSK) chairman as early as this summer.
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FTC puts conditions on Novartis's proposed acquisition of GSK oncology drugs
According to the FTC, Global pharmaceutical company Novartis (NVS) has agreed to divest all assets related to its BRAF and MEK inhibitor drugs, currently in development, to Boulder, Colorado-based Array BioPharma (ARRY) to settle charges that Novartis�s $16B acquisition of GlaxoSmithKline�s (GSK) portfolio of cancer-treatment drugs would likely be anticompetitive...If the acquisition goes forward as proposed, Novartis would likely delay or terminate development of both its BRAF and MEK inhibitors, as well as the combination product. For that reason, Novartis�s acquisition of GSK�s portfolio of cancer-treatment drugs would likely cause significant competitive harm in the U.S. markets for both the BRAF and MEK inhibitors, ultimately raising prices for consumers and depriving them of potentially superior products. Under the terms of the proposed consent agreement, Novartis is required to provide transitional services to Array BioPharma to ensure that development of the BRAF and MEK inhibitors continues uninterrupted and that competition in BRAF and MEK inhibitor markets is not reduced.
Reference Link
February 20, 2015
AbbVie replaces Pfizer as top global pharma pick at Jefferies
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American Academy of Allergy, Asthma and Immunology to hold annual meeting
2015 Annual Meeting of AAAAI is being held in Houston, Texas on February 20-24.
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Oakland, CA (SportsNetwork.com) - Reigning NBA Rookie of the Year Damian Lillard poured in a game-high 21 points to lead the Portland Trail Blazers to a 90-74 win over the Golden State Warriors in the preseason finale for both teams.
LaMarcus Aldridge added 16 points and 12 rebounds, while Robin Lopez and Mo Williams finished with 11 points apiece for the Trail Blazers, who will open up the regular season in Phoenix on Wednesday.
Portland finished the preseason 5-2.
Stephen Curry scored 17 points and Klay Thompson added 16, but the duo went a combined 15-for-42 from the field for the Warriors, who will host the Los Angeles Lakers in their season opener on Wednesday.
Golden State went 3-4 in the preseason.
Dayton's spring football practices will be condensed to a 12-day period in April.
Joe Gibbs Racing announced on Tuesday that David Ragan will drive the No. 18 Toyota in place of the injured Kyle Busch for the next several Sprint Cup Series races, beginning with this weekend's 500-mile event at Atlanta Motor Speedway.
Matt Hasselbeck will be back with the Indianapolis Colts for a 17th NFL season in 2015, as the team announced it has agreed to terms with the veteran quarterback on a one-year contract extension.
The Toronto Blue Jays have signed pitcher Johan Santana to a minor league contract with an invitation to spring training.
Cleveland, OH (Sports Network) - Cleveland Cavaliers guard Kyrie Irving injured his left shoulder in Thursday's 110-99 win over the Golden State Warriors.
The Columbus Blue Jackets acquired forward David Clarkson from the Toronto Maple Leafs on Thursday in exchange for injured forward Nathan Horton.


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Compton, California By Ways Of Portland, Oregon
6'2" 200 lbs
September 2006
The Player "The Player" JT Evans The Kendo Kid JT Twiztid (Masked)
Cadillac Driver(Reverse Pedigree) H8r X-Terminator(Curbstomp) Player Hater(Middle Rope Legdrop)
Chris Hamrick Senior Flamer Liberty Kid Wolfen Black
JT Evans - OWW
Here is a listing of independent wrestling events for the next two weeks. This listing is sent weekly by Nate Stein.
OMEGA Lives crown their first heavyweight champion since 2000
WWE Hall of Fame special to air on USA Network
The Voice of the Fans
CAC Future Legend is busy defending her title
SHIMMER champion Cheerleader Melissa puts the title on the line against Leva Bates. Can Leva beat the odds and score her first major singles title?
WWE tag team legends The Hart Foundation
WCW and TNA Legend


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very true. We spent most of the day running errands
false, unless you count venturing out into the snow to get the mail.
False. I haven't even gone out to check the mailbox yet.
true - dd had dance
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Jei Miranda Savoy's DJ BOOTH PROFILE
Name: Jei Miranda Savoy
Join Date: December 19, 2011 Last Login: January 14, 2012 Total Ratings: 2 |
Jei Miranda Savoy's TOP HIP HOP SINGLES
» View More of Jei Miranda Savoy's Top-Rated Tracks
Jei Miranda Savoy's TOP ALBUMS
» View More of Jei Miranda Savoy's Top-Rated Albums
Note: Favorited tracks and albums no longer show up on member profiles
- Epic Fail: Bobby Shmurda's Label Cashed In & Then Bailed Out
- Open Mic: Why Rappers Need to Play Small Shows
- 1 Listen Album Review: Big Sean's "Dark Sky Paradise"
- Could Kanye's Rapper Reparations Idea Actually Work?
- Every Rapper is Going to Die & So Will I
- An Anti-Elitist Guide to Respecting Gucci Mane
- Breaking Down the Sordid Details of the Lil Wayne vs. Cash Money Lawsuit
- Oh My God, If Drake Dies Is He A Legend?
- Fine, You Got Me: Your Favorite Rapper's First Tweet
- Your Favorite Indie Rapper is Secretly Signed to a Major Label


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Jeremy Chopra's TOP HIP HOP SINGLES
Metis - "Dirty"
"sweet colab.... slickly produced... dirty beats.... IAM ONE and Metis got to smash it more often...." Jeremy Chopra's Rating: Posted on Sep 07, 2011 |
- Epic Fail: Bobby Shmurda's Label Cashed In & Then Bailed Out
- Open Mic: Why Rappers Need to Play Small Shows
- 1 Listen Album Review: Big Sean's "Dark Sky Paradise"
- Could Kanye's Rapper Reparations Idea Actually Work?
- Every Rapper is Going to Die & So Will I
- An Anti-Elitist Guide to Respecting Gucci Mane
- Breaking Down the Sordid Details of the Lil Wayne vs. Cash Money Lawsuit
- Oh My God, If Drake Dies Is He A Legend?
- Fine, You Got Me: Your Favorite Rapper's First Tweet
- Your Favorite Indie Rapper is Secretly Signed to a Major Label


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Zachary Borovay BiographyAlso Credited As: Zachary Borovay News Feeds
Latest News on Zachary Borovay
EVITA National Tour Comes to the Kennedy Center Tonight (Sep 30, 2014)
EVITA National Tour Coming to the Kennedy Center, 9/30-10/19 (Aug 20, 2014)
Recently profiled in the New York Times Sunday Arts & Leisure section, projection designer Zachary Borovay utilizes cutting-edge computer technology and old world techniques to bring a soulful and organic world to life on stage.
BWW TV: One Cast More! LES MISERABLES Welcomes New Broadway Cast Members!BWW TV Exclusive: Renée Fleming & More Get into Character for LIVING ON LOVE; Go Inside the Cast Photo Shoot!BWW TV Exclusive: Spotlight on the Cast of AN AMERICAN IN PARIS- Meet Taeler CyrusVIDEO: Watch Two New Clips from Next Episode of HBO's LOOKINGSTAGE TUBE: Aaron Lazar Performs Cut Song from Sting's THE LAST SHIP at 54 BelowBWW TV: Watch Highlights from Signature Theatre's THE LIQUID PLAIN!BWW TV Exclusive: Spotlight on the Cast of AN AMERICAN IN PARIS- Meet Allison Walsh & Will BurtonSTAGE TUBE: Find Time for Broadway Green Alliance's College Green Captain Prize!VIDEO: Watch CHAPPIE's Hugh Jackman Attend the First Ever Holographic Press ConferenceVIDEO: Judi Dench Teaches Jimmy a Bollywood Dance Move on TONIGHTExtensive New Song-Focused FINDING NEVERLAND Video FeaturetteBWW TV Exclusive: Broadway Legend Barbara Cook Sings the Classics for the AMERICAN SONGBOOK Series!BWW TV Exclusive: Spotlight on the Cast of AN AMERICAN IN PARIS- Meet Victor J. WisehartBWW TV: Watch Highlights of Larry David & More in FISH IN THE DARK on Broadway!
Dan Stevens to Play 'Beast' in Disney's New BEAUTY AND THE BEAST Movie
Bruce Willis & Elizabeth Marvel Are Headed to Broadway in MISERY!
Exclusive: Previously Unreleased Track from SOUND OF MUSIC
Luke Evans to Join Emma Watson in BEAUTY AND THE BEAST Movie
SEINFELD & Theater Star Daniel Von Bargen Dies at 64


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Fiesta Scarlet Bread Tray
Item # HN-HPJC258- Fully vitrified lead-free china with a color glaze
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More Japan
By Jeremiah Jacques, from February 18, 2015 in News »
Several of Asia's ongoing territorial disputes are relics of World War II, but in one part of the region, the war technically never came to an end.
By Andrew Miiller, from January 7, 2015 in Top Stories »
Pornography, anime cartoons, texting, video games and Facebook are pulling an entire generation away from traditional relationships.
By Jeremiah Jacques, from December 28, 2014 in Analysis »
By Jeremiah Jacques, from August 31, 2014 in Top Stories »
Tokyo is wasting no time acting on its new interpretation of its Constitution.
By Jeremiah Jacques, from July 2, 2014 in Analysis »
By Robert Morley, from April 11, 2014 in Analysis »
House prices and debt levels are hitting new records; be worried.


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The owners of the children's show "Sesame Street" have asked the Obama campaign to pull down an ad released Tuesday that shows an image of Big Bird and mocks Republican nominee Mitt Romney for holding up the popular children's character as a symbol of unnecessary government spending.
"We have approved no campaign ads and, as is our general practice, have requested that both campaigns remove Sesame Street characters and trademarks from their campaign materials," said Sesame Workshop, a nonprofit educational organization that produces and owns the show, in a statement. The Wall Street Journal's Peter Nicholas tells Gordon Deal why Sesame Street isn't with President Obama's latest attack ad.
Storms continue to pelt the nation as the calendar turns to march, Netanyahu visit set to test Mideast relations and if you bought a look at your credit score you overpaid.
Could U.S. troops be drawn back in an Iraq war, the biggest cyber threats we face today and Major League Baseball's fight with fatigue.
Islamic State militant known as 'Jihadi John' identified, more airstrikes after Islamic State group kidnaps 220 Christians and political rivals take the fight to Twitter.
Three Brooklyn men arrested and accused of plot to join Islamic State, McConnell faces conservative backlash over compromise to fund DHS and what were you doing when you were 15.
Killer of 'American Sniper' Kyle sentenced to life in prison, compromise offered to end DHS funding fight and stop making these big mistakes on your tax return.
Wake up with America's first news – The Wall Street Journal This Morning. Host Gordon Deal and news anchor Gina Cervetti go beyond the headlines with the day's first look at news and business news from the U.S. and around the world; bringing a lively blend of intelligent information, humor, and expert analysis to morning radio.
Gordon Deal Before taking the helm at The Wall Street Journal This Morning in November 2005, Gordon was well-known to New York City radio listeners, having worked at both WINS-AM and WCBS-AM where he honed his writing skills and developed his distinctive on-air reporting style. He also served as New York City bureau chief for Metro Networks where his reports aired on WOR-AM and WABC-AM.
Gina Cervetti has an extensive radio news anchoring and reporting background including several years at Boston NPR affiliate WBUR-FM where she anchored the local production of "All Things Considered" and "Here and Now." Gina is an Associated Press Award-winning broadcaster, whose reports have been heard all over New England, including WRKO Boston and WTAG Worcester. She graduated from Boston University.
Mike Gavin oversees the production of the show which includes coordinating segments with WSJ reporters, editors, and outside newsmakers. He also oversees the sound and content of the show including all music and sound elements. Mike had spent a decade in radio programming and production before finding a home at WSJ Radio in 2007. He lives at the Jersey Shore with his wife and son.


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Bear hunt application period open
Published 04/16/2012, Wadena Pioneer Journal
Applications for this fall's bear hunt will be accepted from Monday, April 2, through Friday, May 4, at any Minnesota Department of Natural Resources (DNR) license agent and online.
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US 5049374 A Abstract A stabilized oral pharmaceutical bead dosage form of sodium iodide I-131 is described. The sodium iodide I-131 is dissolved in a polymer film and the polymer film is applied by conventional coating technology which affixes the sodium iodide I-131 to inert substrate beads. The film also stabilizes the sodium iodide I-131 from chemical degradation.
The utility of the bead dosage form is that it provides a decreased radiation hazard over that of handling a sodium iodide I-131 liquid. At the time of manufacture a specified amount of sodium iodide I-131 is applied to the substrate beads. The sodium idoide I-131 containing beads are then stored appropriately until dispensed by the pharmacist or physician. The key advantage of this system is that dispensing flexibility is maintained because as the sodium iodide I-131 undergoes radioactive decay the pharmacist or physician can compensate for the loss by dispensing a larger quantity of the coated beads to constitute the prescribed sodium iodide I-131 dose. Then just prior to patient administration, the beads can be filled into a single hard gelatin capsule of if the patient prefers, the beads can be dispensed in water, orange juice, apple sauce or any suitable liquid or food intended for oral administration.
This dosage form described herein minimizes the radiation hazard from the time of manufacture to the time of administration, provides dosing flexibility to the pharmacist and physician and offers the patient numerous options in terms of dosage form administration.
Claims(3) 1. A coated bead pharmaceutical composition for oral administration comprising:
a) inert substrate beads b) a polymer film c) and a radioactive species of sodium iodide wherein said sodium iodide is uniformly dispersed in said polymer film; wherein said polymer film is affixed to said inert substrate beads. 2. The composition of claim 1 wherein said radioactive species of sodium iodide is sodium iodide I-131.
3. The composition of claim 1 wherein said radioactive species of sodium iodide is sodium iodide I-123.
Description Sodium iodide I-131 is frequently used as a marker in nuclear medicine for radionuclide studies involving the human thyroid. It is also used to measure thyroid uptake of iodine, and it is the preferred radiopharmaceutical agent for the identification and assessment of ectopic thyroid tissue. Sodium iodide I-131 is an important adjunct in therapy for thyroid carcinoma for ablation of postsurgical residual thyroid tissue in the neck and eradication of functioning local and distant metastases (1). The doses of sodium iodide I-131 that are used in the treatment of hyperthyroidism and in thyroid carcinoma range from approximately 100 megabecquerels (MBq) to several gigabecquerels (GBq). Sodium iodide I-131 is commercially available for oral administration in aqueous solution and capsule form (2). The liquid dosage form provides the pharmacist and physician with infinite flexibility in dose selection, but it presents significant radiation hazards association with spills; an additional hazard, unique to handling solutions containing sodium iodide I-131, is the inhalation of volatile components containing airborne radiation (3). In solution, sodium iodide can be oxidized to iodine gas by oxygen: 4HI+O2 →2I2 +2H2 O (4). Exposure to light, heat, and other oxidizing agents, such as chloride ions found in tap water, can accelerate the oxidation of the iodide. Schlosser capsule dosage form is the lack of dosing flexibility of the filled capsules. Once the capsules are filled with the predetermined radioactivity it is not possible to alter the dose. This is a problem because the sodium iodide I-131 undergoes radiactive decay and the Stern and Schlosser capsules decrease in activity over time. The sodium iodide I-131 has a half life of 8.06 days, therefore, once the predetermined amount of sodium iodide is filled into the gelatin capsules it is not possible to change the amount of radioactivity, and dosing flexibility is lost because the dose is fixed and can't be individualized to the patient. This means that the physician will have to administer several capsules (usually 2-5) to constitute the correct dose of sodium iodide I-131. This is an inconvenience to the patient and often creates compliance issues. A new dosage form that reduces the hazards of handling sodium iodide I-131 for the radiopharmacist and maintains dosing flexibility for the physician is needed. Rapidly dissolving beads, uniformly coated with a film that is impregnated with sodium iodide I-131, would meet these requirements. This patent describes the development of such a system. The present invention (dosage form) described herein consists of sodium iodide I-131 that is first dissolved in a polymer film and then applied on inert substrate beads through conventional coating technology. As used herein, dosage form is the final composition used for oral administration to humans. In this application, the dosage form consists of the beads layered with a film containing sodium iodide I-131. As used herein, a polymer film is a polymer based layer used to affix the sodium iodide I-131 to the inert substrate beads. As used herein, beads are inert spherical shaped particles ranging in diameter from 250-2,000 microns which are used as substrate upon which the film containing sodium iodide I-131 is applied. The polymer film also stabilizes the sodium iodide from chemical degradation. The sodium iodide I-131 containing beads are then stored appropriately until dispensed by the pharmacist or the physician. The key advantage of this system is that dispensing flexibility is maintained because as the sodium iodide I-131 undergoes radioactive decay the pharmacist or physician can compensate for the decay by dispensing a larger quantity of the coated beads to constitute the prescribed sodium iodide I-131 dose. Then just prior to administration, the beads can be filled into a single gelatin capsule or if the patient prefers, the beads can be dispersed in water, orange juice. Upon oral administration to humans, the gelatin capsule shell is soluble in the gastrointestinal juice thereby exposing the beads. Upon exposure of the coated beads to the gastrointestinal juices the polymer releases the sodium iodide I-131 and the sodium iodide I-131 becomes available in the gastrointestinal tract for absorption into the systemic system. The dosage form described herein minimizes the radiation hazard from the time of manufacture to the time of administration, provides dosing flexibility to the pharmacist and physician, and offers the patient numerous option in terms of dosage form administration. In addition, the composition of the present invention may contain optional pharmaceutically acceptable components which may modify the dose forms physical characteristics. As used herein, a pharmaceutically acceptable component is one which is suitable for use with humans and/or other animals without undue adverse side effects (such as toxicity, irritation and allergic response). The composition of the invention contains sodium iodide I-131 or sodium iodide I-123 as the active ingredient. The substrate bead is used as an inert substrate to which the sodium iodide I-131 containing polymer film is applied. The preferred composition of the beads is a mixture of one or more of the following: sucrose, mannitol, lactose, dextrose, sorbitol, cellulose or starch. The preferred mixture being sucrose and starch. The preferred size of the core beads is in the range of 250-2,000 microns. The most preferred are beads in the range of 400-700 microns. The major purpose of the polymer film is to affix the sodium iodide I-131 to the inert substrate beads. Since sodium iodide is a deliquescent material (it gradually picks up moisture in the air and will turn from dry drug crystals to a liquid), the film protects the sodium iodide from moisture pick up. Sodium iodide also becomes brown in the air because of the liberation of iodine, therefore, the polymer film also prevents this reaction. The polymer film preferably comprises: a) a mixture of hydroxypropylmethylcellulose and ethylcellulose (commercially available as Aquacoat, FMC Corporation). b) a suitable plasticizer preferably dibutyl sebacate Film forming polymers, plasticizers and optional materials are described in the Handbook of Pharmaceutical Excipients (5), incorporated by reference herein. Preferably the polymer or polymers mix can consist of any combination that offers protection against moisture pickup, oxygen transfer and which is designed for immediate release of the sodium iodide I-131 upon human ingestion (by exposure to gastrointestinal juices) Preferably, the polymer material is selected from the group consisting of cellulose ethers, polyvinylpyrrolidone, polyethyleneglycols, methacrylic acid/methacrylic acid ester copolymers and mixtures thereof. Preferred are mixtures of cellulose ethers particularly hydroxypropylmethylcellulose, hydroxypropylcellulose and ethylcellulose. Particularly preferred is a mixture of ethylcellulose and hydroxypropylmethylcellulose. The preferred weight of the applied film on the substrate beads is between 5-25% (weight gain). The most preferred weight is from 5-10% (weight gain). Plasticizers useful in the film include, for example, polyethyleneglycol, glycerin, propylene glycol, triacetin, acetylated monoglycerides, phthalate esters, caster oil, dibutyl sebacate and selected mixtures thereof. The preferred amount of plasticizer is 5-40% to that of the polymer. The most preferred weight is 20-40%. In addition to sodium iodide I-131, polymer film former and plasticizers the film may contain optional fillers, pigments, and dyes. Such fillers include sucrose, kaolin, talc, magnesium stearate, titanium dioxide and mixtures thereof. Such dyes and pigments include those normally used in the pharmaceutical industry. The amount of sodium iodide I-131 applied to the beads in the film may vary depending upon the concentration desired in the finished product. Preferably the concentration of sodium iodide I-131 in the finished product is from several megabecquerels to several gigabecquerels per 1 gram of beads. The amount of sodium iodide containing polymer film applied to the beads is a function of the particular polymer present in the film. The compositions of this invention may be made by standard particle coating devices with appropriate lead shielding. The following are non-limiting examples of compositions and methods for the manufacture of the dosage form. ______________________________________ Substrate Beads - Size: 710-840 microns Weight: 600 grams______________________________________Polymer Film AmountIngredient (% w/w)______________________________________Hydroxypropylmethylcellulose E5 (10% in water) 23.1Distilled Water 34.7Ethylcellulose (Aquacoat dispersion FMC Corp) 38.6Dibutyl Sebacate 2.8Sodium Iodide I-131* --FD&C Red #3 Dye .8 100%______________________________________ *weight of sodium iodide I131 is negligible. 1) A 10% w/w hydroxypropylmethylcellulose (HPMC) E5 solution was prepared in distilled water and deaerated overnight at 5� C. 2) The Aquacoat (FMC) was plasticized with dibutyl sebacate. The dibutyl sebacate was added to the Aquacoat and mixed for 30 minutes with a Lightnin mixer. 3) The sodium iodide I-131 was dissolved in a portion of the distilled water and added to the HPMC solution. 4) FD&C Red #3 dye was added with mild agitation to the HPMC solution. 5) The HPMC mixture was added to the Aquacoat mixture and mixed for 20 minutes before coating and throughout the coating process. Using appropriate lead shielding, 600 g of the 710-840 microns beads were coated in a fluidized-bed coating column with an inlet coating temperature of 50� C. The sodium iodide polymer film was pumped at a rate of 6 g/min into the atomizer, which operated at a spray pressure of 2 atmospheres and had a spray-nozzle orifice of 1.1 mm. After coating, the beads were dried on trays at 45� C. for 24 hours. ______________________________________ Substrate Beads - Size: 590-840 microns Weight: 500 grams______________________________________Polymer CoatingIngredient Amount (% w/w)______________________________________Methacrylic acid ester copolymers 8(Eudragit E-100)Acetone 24Isopropyl Alcohol 56Polyethylene Glycol 3350 2FD&C Yellow #6 Dye .02Titanium Dioxide 1.4Purified Water 8.6Sodium Iodide I-131* -- 100%______________________________________ *The weight of sodium iodide I131 is negligible. The composition is made by a method essentially similar to that in Example 1. ______________________________________ Core Beads - Size: 800-1,000 microns Weight: 600 grams______________________________________Polymer CoatingIngredient Amount (% w/w)______________________________________Hydroxypropylcellulose E5 10Polyvinylpyrrolidine 5Distilled Water 76.9Polyethylene Glycol 8000 4Talc 4.0Blue Dye .1Sodium Iodide I-131* -- 100%______________________________________ *The weight of sodium iodide I131 is negligble. The composition is made by a method essentially similar to that in Example 1. 1) Mettler, F.A. and Guiberteau, M.J., Thyroid and parathyroid. In Essentials of Nuclear Medicine Imaging, 2nd Edition, Harcourt Brace Javanovich, Orlando, 1986, pp. 89-115. 2) United States Pharmacopeia, National Formulary USP XXII, NF XVII, The United States Pharmacopeial Convention, Inc., 12601 Twinbrook Parkway, Rockville, Md. 20852 pp. 709-710, 1990. 3) Haenchen, M., Eichling, J. and Glasgow, G., Assessment of the airborne activity levels during I-131 thyroid therapies. Poster presented at the 30th Annual Health Physics Society Meeting, Chicago, June 1985. 4) Howard, B.Y., Safe handling of radioiodinated solutions. J. Nucl. Med. Technol., 4 (1986) 28-30. 5) Handbook of Pharmaceutical Excipients, Published by the American Pharmaceutical Association, 2215 Constitution Ave., NW, Washington, D.C. 20037, 1980. Patent Citations
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Even though I'm taking a sabbatical from sex due to my health and taking care of mom, I seem to be losing guys that I am interested in getting together with on occasion. My twink that I had over twice blocked me on Grindr awhile ago and never came over one Saturday when he said he would and after I gave him $80 for both Friday and Saturday that week. The reason I gave him money is because he needed it for gas and weed allegedly, even though I knew it was more like prostitution, but I couldn't resist that boy and his perfect body. I feel ashamed for giving him money now and not being able to fuck him anymore. I wanted him all the time, but he doesn't know that.
A straight guy I sucked and rimmed in his van on a country road blocked me on Meetme and ignored my texts today. Not sure what caused that sudden change, but it alarmed me a bit, especially since he enjoyed it and said I did it better than the girls he's been with and we talked about a lot of different things. Straight guy problems on his part I guess?
Am I a fool for wanting these guys for good sex? I don't have to have sex with them all the time, and I've told them that we can just hang out, but that's not good enough and they go and block me and cut me out. Who else has this kind of bad luck where EVERY single guy you've been with doesn't come back for more and doesn't even consider friendship either? I guess it's awkward to be friends after fucking, but it's even more strange to do it once and never come back, leaves an unpleasant feeling inside you. I feel selfish for wanting sex and the company of a guy, though it helps with my anxiety to be near a guy and I can relax and enjoy being with one.
I deleted my accounts on Adam4Adam and Grindr, but might go back once I am well again and when mom is better. What bothers me is that if and when I go back, the guys I had sex with from there won't want anything to do with me and the guys I talked to on a friendly level or wanted to talk to will just ignore me. So difficult for me to make friends anymore and/or to find guys I want to hook up with, since my preferred ones are ignoring me and my "options" are dwindling. What does a guy like me do?