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Genetic diversity in Capsicum baccatum is significantly influenced by its ecogeographical distribution
- Elena Albrecht,
- Dapeng Zhang,
- Anne Deslattes Mays,
- Robert A Saftner,
- John R Stommel
- … show all 5 hide
The exotic pepper species Capsicum baccatum, also known as the aji or Peruvian hot pepper, is comprised of wild and domesticated botanical forms. The species is a valuable source of new genes useful for improving fruit quality and disease resistance in C. annuum sweet bell and hot chile pepper. However, relatively little research has been conducted to characterize the species, thus limiting its utilization. The structure of genetic diversity in a plant germplasm collection is significantly influenced by its ecogeographical distribution. Together with DNA fingerprints derived from AFLP markers, we evaluated variation in fruit and plant morphology of plants collected across the species native range in South America and evaluated these characters in combination with the unique geography, climate and ecology at different sites where plants originated.
The present study mapped the ecogeographic distribution, analyzed the spatial genetic structure, and assessed the relationship between the spatial genetic pattern and the variation of morphological traits in a diverse C. baccatum germplasm collection spanning the species distribution. A combined diversity analysis was carried out on the USDA-ARS C. baccatum germplasm collection using data from GIS, morphological traits and AFLP markers. The results demonstrate that the C. baccatum collection covers wide geographic areas and is adapted to divergent ecological conditions in South America ranging from cool Andean highland to Amazonia rainforest. A high level of morphological diversity was evident in the collection, with fruit weight the leading variable. The fruit weight distribution pattern was compatible to AFLP-based clustering analysis for the collection. A significant spatial structure was observed in the C. baccatum gene pool. Division of the domesticated germplasm into two major regional groups (Western and Eastern) was further supported by the pattern of spatial population structure.
The results reported improve our understanding of the combined effects of geography, ecology and human intervention on organization of the C. baccatum genepool. The results will facilitate utilization of C. baccatum for crop improvement and species conservation by providing a framework for efficient germplasm collection management and guidance for future plant acquisitions.
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- Title
- Genetic diversity in Capsicum baccatum is significantly influenced by its ecogeographical distribution
- Open Access
- Available under Open Access This content is freely available online to anyone, anywhere at any time.
- Journal
BMC Genetics
- Online Date
- August 2012
- 10.1186/1471-2156-13-68
- Online ISSN
- 1471-2156
- Publisher
- BioMed Central
- Additional Links
- Topics
- Authors
- Elena Albrecht (1)
- Dapeng Zhang (2)
- Anne Deslattes Mays (1)
- Robert A Saftner (3)
- John R Stommel (4)
- Author Affiliations
- 1. Keygene Inc., 155 Gibbs Street, Suite 405, Rockville, MD, 20850, USA
- 2. United States Department of Agriculture, Agriculture Research Service, Beltsville Agricultural Research Center, Plant Sciences Institute, Sustainable Perennial Crops Laboratory, Beltsville, MD, 20705, USA
- 3. United States Department of Agriculture, Agriculture Research Service, Beltsville Agricultural Research Center, Plant Sciences Institute, Food Quality Laboratory, Beltsville, MD, 20705, USA
- 4. United States Department of Agriculture, Agriculture Research Service, Beltsville Agricultural Research Center, Plant Sciences Institute, Genetic Improvement of Fruits and Vegetables Laboratory, Beltsville, MD, 20705, USA


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[QUOTE=RMS123;1202281]You have a very nice writing style. I remember enjoying your posts from your time in Africa. Bet your novel is going to be great![/QUOTE]Thank you. I appreciate that. It may or may not ever get published but the process is interesting.
[QUOTE=cori93437;1202289]That quote "[B]The cure for anything is salt water - tears, sweat, or the sea[/B]." -Isak Dinesen, from Seven Gothic Tales (Same dude who wrote Out of Africa) is the reason to live near the ocean/sea.
I aspire to that. Seriously. It's my dream to move south and to the coast... or just to the coast left or right at minimum.
I want to be able to go out and sit on my own dock and drink coffee, and jump in my yak and paddle whenever, and catch the fishes and eat them for dinner.
Also. Sex. Yeah... that stuff is important.
I can't believe how many people underestimate this.
I made husband pause the fights last night for a bit.
[B]15 years and we still got it. :o[/B][/QUOTE]That quote is so true. And you and your hubs give me hope for longer term relationships. I have never managed anything past about four years at a stretch in my life.

subset: commoncrawl


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Sunday, March 06
Camelback Ranch - Glendale, AZ
Attendance: 4,197
Glendale, AZ (Sports Network) - Clint Robinson went 2-for-5 with two runs batted in and Mike Aviles added three hits and scored twice as Kansas City knocked off the Chicago White Sox, 8-3, in Cactus League play.
Lance Zawadzki and Pedro Feliz hit home runs for the Royals, who banged out 17 hits. Luke Hochevar earned the win after allowing a run on three hits over three frames in the start.
Adam Dunn had two hits and an RBI while Juan Pierre, Brent Lillibridge and Tyler Flowers also had a pair of hits for the White Sox.
Mark Buehrle took the loss after getting roughed up for five runs on nine hits over three frames.
Eric Loveless
Chris Guccione
Mark Ripperger
Chris Ward


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This native South Carolinian offers up what he calls "Island-infused drum 'n' bass, gospel-Ninja-soul" to crowds of dancers at clubs from coast to coast. The jam band scene knows Zach Deputy as a one-man band ...
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Fracking Boom Gives U.S. Geopolitical Leverage
Steve Inskeep talks to Gregory Zuckerman, a senior writer with The Wall Street Journal, about how the fracking boom has given the U.S. power in pushing for an agreement with Iran on its nuclear weapons program. Zuckerman is the author of The Frackers: The Outrageous Inside Story of the New Billionaire Wildcatters.
Copyright © 2013 NPR. For personal, noncommercial use only. See Terms of Use. For other uses, prior permission required.
American oil production has grown so much that it may affect American global strategic thinking. The technology known as fracking has allowed a flood of previously inaccessible oil.
It has also prompted a flood of questions about polluting ground water and other environmental effects. But fracking has given the global oil market a fresh source of supplies.
MONTAGNE: That allows the U.S. and other nations the freedom to take steps, like choking off the supply of oil from Iran. U.S.-led sanctions have intensified against Iran, which hasn't sold oil directly to the U.S. for years, but has sold a lot of oil to India and China.
INSKEEP: That pressure has prompted Iran to engage in nuclear negotiations this fall. Those watching the story includes The Wall Street Journal's Gregory Zuckerman, author of a new book called "The Frackers."
GREGORY ZUCKERMAN: Oil prices are really set by global buyers and global sellers. So the fact that you've got Iran, which is producing about half of what it was producing just a few years ago in crude, but we're taking up the slack that really has helped us keep a lid on oil prices internationally.
INSKEEP: Work me through some numbers here. How many barrels of oil per day is the world using right now?
ZUCKERMAN: Right now it's about 89 million barrels per day. And we, the United States, are responsible for production of about nine percent of that - about eight million barrels. And that's up since 2005, when we were at about five million barrels. We've added about four percent to the global supply of crude.
INSKEEP: That's a big deal.
ZUCKERMAN: It is. And at the margin, it's a really big deal. It's not to say people kind of say to me well, Greg, you wrote this book about the energy revolution, why aren't I paying a lot less at the pump? And I'm not sure we're going to be paying a lot less at the pump, but it's relative to what we would have to pay. Had this revolution not taken place we wouldn't have been able to do the kind of sanctions and boycotts of Iran that we've orchestrated and we would be paying a lot more. And so it has had an effect for consumers.
INSKEEP: Are you willing to argue that if the United States had not been able to boost its production of oil in the last several years that the global sanctions regime against Iran would be a lot weaker - would have fallen apart? There would be other countries that would say there's just not enough oil in the world, we need Iran's oil far more badly than you realize, America?
ZUCKERMAN: Yeah. I do think that the temptation to not participate in the sanctions of Iran would've been much greater had it not been for this fracking and energy revolution in the United States. It's not to say that we wouldn't have had partners and allies in the effort, but not everyone would've participated like they are today.
INSKEEP: You know, it's nice to be able to think that the United States would be less dependent on a frequently unstable region like the Middle East. But is that something of an illusion? Because it is a global market and if supplies from Saudi Arabia say, are disrupted or supplies from Iraq are disrupted, even if that oil wasn't going directly to the United States, it's going to affect oil prices in the United States.
ZUCKERMAN: That's exactly right. As long as we care about oil, we're going to care about the Middle East. But at the margin, it's going to give us a lot more flexibility. I really think that we are going to be less involved in the Middle East. And I really think countries like China are going to become more important and more involved in the Middle East. And frankly, the kind of military experts I talked to are still trying to figure out if that's a good thing or a bad thing. But either way we're going to be much less dependent on the Middle East and much less involved in the Middle East and energy is going to play a much bigger role.
Last year, Hillary Clinton, when she was Secretary of State, she created a dedicated energy bureau within the State Department, and she said energy is going to play a bigger role in future diplomacy, and I think that's really going to be the case.
INSKEEP: So let me just make sure I understand where the numbers are headed. You're saying that a few years ago the United States was producing five million barrels of oil per day - which is a lot but not nearly as much as we consume, it's now gone up very quickly to eight million barrels of oil per day. What's the upper end? How high can it go?
ZUCKERMAN: Some people say we could hit 11. There is a lot of discrepancy and disagreement about the shale wells that are key to it all because their production falls out very quickly. Some skeptics say nah, we are never going to kind of get energy independence. I kind of agree. I think energy independence is a little overstated and we can really hope for that. But I think energy's secure over the next few years, meaning we depend on some of our allies. Mexico and Canada are much less reliant on places like the Middle East. It's all very healthy. I don't know, frankly, how long it's going to last, maybe a last five years or 10 years, but for that period it'll be very healthy for us.
INSKEEP: Gregory Zuckerman of The Wall Street Journal. His book is called "The Frackers." Thanks very much.
ZUCKERMAN: Sure. Great to be here.
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Sprint affiliate sues over Virgin deal
KANSAS CITY, Mo. (AP) – Sprint Nextel Corp. affiliate iPCS Inc. is asking an Illinois court to block the wireless provider's planned acquisition of Virgin Mobile USA Inc., while Deutsche Telekom has called in banking advisers to study a possible multi-billion-dollar bid for Sprint.
Three subsidiaries of Schaumburg, Ill.-based iPCS filed the lawsuit last week in the Circuit Court of Cook County, seeking an injunction to stop the $483 million deal. They claim it would violate an agreement by Sprint not to compete against iPCS within its territories.
iPCS sells Sprint-branded products and services within a swath of the Midwest.
"This is now the third time in four years that Sprint has attempted to unlawfully compete against and cannibalize its own affiliates," the lawsuit states.
Matt Sullivan, a spokesman for Overland Park, Kan.-based Sprint, said the company was fighting the lawsuit. "We think the claims are without merit," he said.
Sprint and iPCS have battled in the courts before over Sprint's 2005 acquisition of Nextel Communications Inc. and last year's deal with Clearwire Corp. to provide high-speed wireless Internet services – also under the claim that they violated the exclusivity agreement.
A Cook County judge agreed with iPCS on the Nextel deal, ordering Sprint to cease operating its Nextel network in iPCS' markets. Sprint announced in June that it planned to turn over ownership and operation of its Nextel-branded network in parts of Illinois, Iowa, Michigan and Nebraska.
Several Sprint affiliates sued shortly before and after the Nextel purchase, leading the company to buy most of them. The company hasn't said whether it plans to acquire iPCS.
The lawsuit regarding the Clearwire deal is still pending. Sprint merged its WiMAX network with Kirkland, Wash.-based Clearwire last fall.
IPCS has since amended that suit to allege that Sprint is providing "advanced technologies" to Clearwire in violation of its affiliation agreement and will seek damages.


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School District 2 hopes it will find the best people for its committee tasked with redrawing school boundaries.
Members of the board's planning and development committee looked at draft applications at their meeting Monday night. District leaders hope to have a final application ready to go out to the public in a couple weeks.
The district is looking for roughly 20 people — parents, community leaders, SD2 employees, trustees and planning experts — to sit on the committee that will readjust or fix school boundaries across the city.
"I want it to go smoothly, and to go smoothly, you need reasonable people," said Superintendent Terry Bouck.
Trustees hope to have a method in place for selecting committee members and giving them direction by their regular board meeting in two weeks.
They'd like to have the committee formed by late June or early July.
Also at the meeting Monday night, trustees talked about updating the district's scoreboards. Mark Wahl, SD2's director of activities, talked about options for replacing and updating scoreboards and possibly using advertising to help cover some of the cost.
The state offers loans to school districts specifically for purchasing scoreboards. The loans are offered at roughly 2 percent and are paid back over seven years.
Trustees are looking at four options that would cost between $805,000 and $1.3 million.
With new scoreboards in place, the district would have the option of selling ad space on them to area businesses and merchants, Wahl said.
Finally, trustees heard updates on the McKinley and Broadwater elementary school renovation projects and the new new middle school designs.
The work at McKinley and Broadwater is being overseen by CTA Architects. Work will begin as soon as school lets out next month. CTA has hired contractors for the window replacement and masonry work. Bids for both projects came in on budget.
For the new middle school in the Heights, A&E Architects is in the process of meeting with middle school teachers from across the district to give feedback on the space and function design of the new middle school's classroom.
Design work on the school will finish up this year and construction will begin next spring.


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Months Into Mission, U.S. Action Against Kony Unclear
By editor
Originally published on Wed April 18, 2012 5:54 pm
In the Central African Republic, U.S. Special Forces soldiers are on the hunt for Joseph Kony, the brutal leader of the rebel group the Lord's Resistance Army (LRA). The LRA has been responsible for abducting tens of thousands of children and turning them into sex slaves or killers. The U.S. military set up its outpost in the country four months ago. Audie Cornish talks to Washington Post reporter Sudarsan Raghavan, who wrote about the U.S. involvement.


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food for thought!
(10 Recipes) Created by DZEISSET1
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This recipe is really easy; it's really more of a process than a recipe. Rice paper wrappers, which are available in the ethnic sections of most larger supermarkets these days, are a great way to wrap your veggies and protein for a quick snack or light lunch. Submitted by CHEF_MEG Carbs: 18.3g | Fat: 1.9g | Fiber: 3.8g | Protein: 16.6g | Calories: 156.4
Sweet and tangy oranges pair perfectly with rich, salty miso. Submitted by CHEF_MEG Carbs: 7.9g | Fat: 9.3g | Fiber: 1.1g | Protein: 29.3g | Calories: 236
This low-calorie, low-fat version of the classic BBQ sandwich will be a new family favorite! Submitted by INFJMJ Carbs: 22.8g | Fat: 4g | Fiber: 5g | Protein: 22.1g | Calories: 200.7
A low fat take on a New Orleans favorite Submitted by DEBBEV Carbs: 7.1g | Fat: 5.2g | Fiber: 0g | Protein: 32g | Calories: 217.3
This is a delicious chicken recipe that my family loves Submitted by ALECSANDRA Carbs: 4.3g | Fat: 8g | Fiber: 0g | Protein: 19.4g | Calories: 166.4
Citrus and cilantro dress up grilled fish. Submitted by CHEF_MEG Carbs: 12.8g | Fat: 8.4g | Fiber: 2.7g | Protein: 29.1g | Calories: 240.6
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These are a yummy treat, hard not to over indulge! I got this from the Kraft Foods website Submitted by CSHOLL24 Carbs: 5.6g | Fat: 5.7g | Fiber: 0.2g | Protein: 3.6g | Calories: 87.8
These crab cakes skimp on fat but not on flavor. They're packed with chunks of rich crab. Submitted by LOSER1231 Carbs: 8.1g | Fat: 2.5g | Fiber: 0.5g | Protein: 17.1g | Calories: 129.2
Fresh and juicy during spring and summer months, strawberries are delicious when combined with tender spinach, creamy goat cheese and crunchy toasted almonds. Submitted by CHEF_MEG Carbs: 6.4g | Fat: 16.6g | Fiber: 2.3g | Protein: 4g | Calories: 181.2


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Greece's sovereign debt may fall to as low as 116 percent of the nation's gross domestic product by 2020 if a larger number of private sector institutions participate in a debt swap, Reuters reported, citing two unidentified European Union officials.
That level of indebtedness would be below the 120 percent the International Monetary Fund views as sustainable and compares with a target of 121.5 percent under the current participation rate in the debt swap of 96 percent, the newswire reported.
To contact the reporter on this story: Cornelius Rahn in Frankfurt at firstname.lastname@example.com
To contact the editor responsible for this story: Kenneth Wong at email@example.com


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>Why To Live
That sounds simple enough, just find out why to live. However, what struck me as I
uploaded this just now is that those people who have to struggle desperately with 'how'
to live (poverty, war, concentration camps, illness) are the ones that usually find out
the 'why'. Sort of a chicken or the egg type thing I suppose?


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GPhotos multiple scripts cross-site scripting
gphotos-multiple-xss (26426) | Medium Risk |
GPhotos is vulnerable to cross-site scripting, caused by improper validation of user-supplied input by the index.php, diapo.php or affich.php script. A remote attacker could exploit this vulnerability using the 'rep' or 'image' parameter to execute script in a victim's Web browser within the security context of the hosting Web site, allowing the attacker to steal the victim's cookie-based authentication credentials.
Gain Access
No remedy available as of September 1, 2014.
- BugTraq Mailing List, Sat May 13 2006 - 06:22:10 CDT: Gphotos Directory Traversal and Cross Site Scripting.
- ComScripts.com Web site: Gphotos.
- BID-17967: Gphotos Multiple Input Validation Vulnerabilities
- CVE-2006-2397: Multiple cross-site scripting (XSS) vulnerabilities in GPhotos 1.5 and earlier allow remote attackers to inject arbitrary web script or HTML via the (1) rep parameter to (a) index.php or (b) diapo.php or (2) image parameter to (c) affich.php. NOTE: item 1a might be resultant from directory traversal.
- OSVDB ID: 25497: GPhotos index.php rep Parameter XSS
- OSVDB ID: 25498: GPhotos diapo.php rep Parameter XSS
- OSVDB ID: 25499: GPhotos affich.php image Parameter XSS
- SA20095: GPhotos Cross-Site Scripting and Disclosure of Arbitrary Directories
Platforms Affected:
- Visialis Gphotos 1.5
May 13, 2006
The information within this database may change without notice. Use of this information constitutes acceptance for use in an AS IS condition. There are NO warranties, implied or otherwise, with regard to this information or its use. Any use of this information is at the user's risk. In no event shall the author/distributor (IBM Internet Security Systems X-Force) be held liable for any damages whatsoever arising out of or in connection with the use or spread of this information.
For corrections or additions please email ignore thisxforceignore this@ignore thisus.ignore thisibm.comignore this


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In The Box | |
Sales Package | AMD Processor, Installation instructions, Limited Warranty information and a thermal solution designed for use in a desktop pc |
Memory | |
Maximum Memory Bandwidth | 21.3 GB/s |
Memory Channels Supported | 2 Channel |
Memory Type Supported | DDR2-1066, DDR3-1333 |
General | |
Voltage Range | 0.825 V - 1.40 V |
Cache Memory | 128 KB (L1), 2 MB (L2) |
Speed | 3.2 GHz |
Manufacturing Process | 45 nm |
Maximum Thermal Design Power [TDP] | 65 W |
Bus-Core Ratio | 16 |
Number of Cores | 2 Cores |
Warranty | |
Domestic Term | 3 Year |
Warranty Summary | To obtain warranty service for your AMD Processor in a Box, contact your computer system manufacturer or distributor during the systems warranty period. After your computer system warranty has expired, you can submit a warranty request to AMD Customer Care. To submit a warranty claim visit http://www.amd.com/WarrantyServices. |
Service Type | Carry In |
Warranty Type | Limited |
Not Covered in Warranty | This limited warranty does not cover any costs relating to removal or replacement of any AMD processor or any other cost associated with replacement for the AMD processor. This limited warranty does not cover damages due to external causes, including improper use, problems with electrical power, accident, neglect, alteration, repair, improper installation, or improper testing. This Limited Warranty shall be null and void if the AMD microprocessor which is the subject of this Limited Warranty is used with any heatsink/fan other than the one provided herewith. |
General Features | |
Brand | AMD |
Virtualisation | Yes |
Threading/Transport | Yes |
Type | Desktop |
Series | Athlon II |
Architecture | 64-bit |
Instruction Sets | SSE, SSE2, SSE3, SSE4a, MMX |
Model ID | Athlon II 260 |
Socket Type | AM3 |
Please Note: All products sold on Flipkart are brand new and 100% genuine
Feb 14, 2013
Look No Further
Feb 9, 2013
$hawn Noronha
Feb 1, 2013
Very affordable dual core. RAVI KISHORE G. is a bit misinformed, understand the Truth.
Jan 31, 2013
VFM processor
Deepak Malik
Dec 21, 2012
Using this from august 29, 2012
'Top Reviews' lists the most relevant product reviews only. Show ALL instead?
Expand all ReviewsPushkar Patili
Dec 4, 2011
Amazingly COOL!!!
I'm using this processor on a Gigabyte board and 2 GB Transcend RAM. I haven't seen CPU temperature goes above 28 C. when surfing, working with office documents and even playing videos.Sandip Kumar
Mar 13, 2012
A beautiful mind!
Flipkart, you rock as always!Jay Shree Kant Shreevastava
Jan 30, 2012
Mind Blowing Performance !!
I am already FAN of AMD. this processor can be used for mid level gaming purposes. it has excellent performance. by using it with a ATI RAEDON graphic card it boosts ...Deepak Malik
Dec 21, 2012
Using this from august 29, 2012
I am an average user most of the time i just surf the net, watch youtube, read office documents,large PDF files and watch movies (in 720 HD also).Shlok Johri
Sep 1, 2012
Great Buy - At par with core i3 probably better
Got this great processor from flipkart along with a Gigabyte GA-78LMT-S2PT Motherboard, G.Skill NT DDR3 4 GB RAM and a otac NVIDIA GeForce GT210 1 GB graphics card. Had an old cabinet and am still using an IDE Seagate HDD & an IDE DVD drive...$hawn Noronha
Feb 1, 2013
Very affordable dual core. RAVI KISHORE G. is a bit misinformed, understand the Truth.
This is a very good dual core processor for the price, and its compatible with AM2+, AM3 as well as AM3+ socket motherboards if proper BIOS support is provided. :) Really good deal, especially if your upgrading from some of the older generation AMD chips.Rangan Das
May 7, 2012
Top of the line Dual Core processor.
With Dual Core processors becoming dated, AMD Athlon II X2 Regor 3.2 GHz is one processors that bring dual core computing back to life. The frequency multiplier is locked, so it can be overclocked by changing bus speed only, and amazingly, it crossed the 4GHz mark. I run it at 3.7GHz and it's stable (overclocked with ASUS TurboKey). In case of single core performance, it outruns many newer processors.MACJAN CAMILO FERNANDES
Jan 23, 2012
Best for performance at medium level gaming
I only what to say that I have seen my single core celeron ,core2 duo and i3 processors working at 48 to 62 Degrees but this one has beaten all of them up..ANAND
Oct 27, 2012
BEST PROCESSOR FOR HOME USE...GO FOR IT RATHER THAN INTEL DUAL CORES OR I3 PROCESSORS,ITS TIME TO BE AMD...Ravi
Feb 14, 2013
Look No Further
Good budget processor with killer specs. My earlier intel c2d was noisy and slow and sluggish on multitasking like listening to music while some ofiicial work on MS office and opening more than 2-3 tabs on chrome but with this I'm able to open 10-15 tabs without any hiccup with other programs running at background! Gaming is great and much beteer in compare to c2d or i3 I have used at friend's place.


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EP Plenary debate: preparation for Spring European Council
Vice-President Maroš Šefčovič took part on Wednesday in the European parliament debate in Strasbourg on the preparation for next month's European Council meeting.
He presented the Commission's position ahead of the Council meeting, which like all Spring summits is to focus on economic and financial issues. He underlined the findings of the Commission's Annual Growth Survey for 2012, which focuses on five priority areas: promoting differentiated growth-friendly fiscal consolidation; restoring normal lending to the economy; boosting long-term growth and competitiveness; tackling unemployment and the social consequences of the crisis; and modernising public administration.
As the first so-called 'action teams' of Commission and national officials begin their visits to the eight Member States with the highest levels of youth unemployment, V-P Šefčovič also reiterated the need for concerted efforts from all Member States to promote growth and create jobs, in particular among young people. He also presented MEPs with the findings of the Commission's first Alert Mechanism Report – part of the 'six pack' of measures adopted late last year to improve long-term economic governance – which shows that 12 Member States are at risk of macroeconomic balances.


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Capt. James Loomis House (1828)
Friday, November 21st, 2014 Posted in Federal Style, Greek Revival, Houses, Windsor | Comments OffThe brick house at 881 Windsor Avenue in Windsor was built around 1825-1828 by Capt. James Loomis. A transitional Federal/Greek Revival house, it is one of several in the vicinity built by members of the Loomis family.
Captain Benjamin Allyn II House (1760)
Tuesday, September 16th, 2014 Posted in Colonial, Houses, Windsor | Comments OffLocal tradition holds that the house at 119 Deerfield Road in Windsor was built in 1670 and associates it with Thomas Allyn (1635-1696), which would make it a very early example indeed of a brick house. The house has wood framing which is tied into the brick walls with iron tie-plates. These plates once featured the date of the house, but only the "1" and the "0" survive, although it is agreed that the missing numerals were "6" and "7." While this could have been 1670, it is more likely, based on architectural evidence and Henry R. Stiles' History of Ancient Windsor, that house was built in 1760, probably by Captain Benjamin Allyn II, a descendent of Thomas Allyn. Thomas Eggleston is said to have provided the bricks for the house.
Daniel Payne House (1830)
Saturday, July 19th, 2014 Posted in Houses, Vernacular, Windsor | Comments OffBuilt around 1830, the house at 27 Park Avenue in Windsor is one of many examples in the town of early nineteenth-century brick construction. The earliest known owner of the house was Clarissa Loomis, who sold it to Daniel Payne, a farmer, in 1855.
John Fitch School (1921)
Tuesday, June 17th, 2014 Posted in Neoclassical, Schools, Windsor | Comments OffThe John Fitch School, at 156 Bloomfield Avenue in Windsor, was built in 1921. It was named in honor John Fitch, who was wounded in King Philip's War and returned to Windsor where he died in 1676. He left his estate to the town to be used in establishing a school. His bequest continued to help finance higher education in Windsor for 200 years. The Fitch School was designed in the Beaux Arts style by William Henry McClean of Boston. An addition was constructed in 1929 and this addition was expanded to the rear in 1934. Originally a high school it became an elementary school in the 1950s and was converted to senior housing in the 1990s. Read the rest of this entry »
John Moore House (1675)
Tuesday, May 27th, 2014 Posted in Colonial, Houses, Windsor | Comments OffJohn Moore (1645-1718), the eldest son of Deacon John Moore, built the central-chimney saltbox house at 390 Broad Street in Windsor in 1675. He had married Hannah Goffe in 1664. After her death he married Martha Farnsworth in 1701. By 1715 Moore had married his third wife, Mary. A description of the house from 1940 mentions that it had a new front porch and a bay window on the south. These later additions have since been removed and the house restored to a seventeenth-century appearance. Read the rest of this entry »
Col. James Loomis House (1822)
Tuesday, September 24th, 2013 Posted in Federal Style, Houses, Windsor | Comments OffThe house at 208 Broad Street in Windsor was built in 1822 for Colonel James Loomis (1779-1862). Built of bricks manufactured by the Mack Brick Company in Windsor, it was once one of a number of residences that once stood on Broad Street across from Broad Street Green. A descendant of Joseph Loomis, who settled in Windsor in 1639, Col. Loomis was the proprietor of the village store, which stood just south of his house. His wife, Abigail Sherwood Chaffee Loomis (1798-1868), inherited Nancy Toney (1774-1857), Connecticut's last enslaved person, in 1821. The children of James and Abigail would found what is now the Loomis Chaffee School. The house remained a residence until 1970, when it was converted into a bank.
Quartus Bedortha House (1835)
Wednesday, January 30th, 2013 Posted in Federal Style, Greek Revival, Houses, Windsor | Comments OffAmong the numerous brick houses built in Windsor in the early nineteenth century is the Quartus Bedortha House at 54 Poquonock Avenue. It was built by Quartus Bedortha in 1835. He was born in Agawam, Mass. on February 21 1808, married Ruth Loomis on February 28, 1832 (they had two children) and died on August 4, 1879.


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Took these shots of images of chicken which I transformed into my art. Used the same roll during an afternoon swim while in Rio. Unlike an older album I posted, this set didn't successfully expose the second layer which was self-portraits underwater. Nevertheless, the shots well captured the textures and colors I used around the fowl.
This photo was shot on film. Taken by lakandula with a Canon A1 x Fisheye loaded with Fuji Provia 100F 35mm film in Muntinlupa City + Rio de Janeiro, Brazil, Philippines. These tags describe this photo: chicken, doubles, artwork, self-portraits, swimming, pool, and xpro. Date: 2011-04-26. Time: Afternoon. This photo can also be found in the albums S-E-O-U-L Isn't Hard To FindFoul Fowl Doubles.Please login to get more out of this site
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Form: Customize this purging letter to get in touch with long-lost clients
Oct 06, 2011
Need to get in touch with clients you haven't heard from in a while? Use this purging letter to find out whether your veterinary practice should keep their files active. Click here to download the form.
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ALBANY, N.Y., June 27, 2013 /PRNewswire/ -- Trans World Entertainment Corporation (Nasdaq: TWMC) today announced that its Board of Directors (the "Board") has authorized the Company to repurchase shares of the Company's common stock in a "modified Dutch auction" tender offer for up to $25 million in value of its common stock, at a price of not less than $4.50 and not greater than $5.10 per share (in increments of $0.05) (the "Tender Offer"). This price range represents a 13% premium to a 28% premium to the average closing price per share for the Company's common stock for the last 120 days.
A "modified Dutch auction" tender offer allows shareholders to indicate how many shares and at what price(s) they wish to tender within the Company's specified price range. Based on the number of shares tendered and the prices specified by the tendering shareholders, the Company will determine the lowest price per share within the range that will enable the Company to purchase $25 million in value of its common stock (or a lower amount if the offer is not fully subscribed). All shares purchased by the Company in the Tender Offer will be purchased at the same price.
In the fourth quarter of the fiscal year ended February 2, 2013, the Company declared and paid a special cash dividend of $0.47 per share, the first dividend in the Company's history. This was a one-time special dividend and does not guarantee any future dividends. In deciding to authorize the Tender Offer, the Board carefully reviewed various alternatives, including the payment of one-time and regular dividends, for returning capital to the Company's shareholders and increasing long-term shareholder value. The Board determined that the Tender Offer would be the most prudent and effective way to return capital to the Company's shareholders and increase long-term shareholder value. The Board concluded that the Tender Offer would, among other things, permit shareholders desiring liquidity to reduce their holdings at a time when the Company's stock price is at or near a five-year high and permit remaining shareholders to benefit from increased future earnings per share.
Robert J. Higgins, Chairman of the Board and Chief Executive Offer did not participate in any of the Board's decisions regarding the Tender Offer.
The Company expects to fund the Tender Offer from cash on hand and does not expect to borrow any funds for the purpose of the Tender Offer. The Tender Offer will be subject to a number of terms and conditions, which will be specified in the offer to purchase and the other documents relating to the Tender Offer. The Company anticipates commencing the Tender Offer in the near future.Check Out Our Best Services for Investors
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Imray Chart 2300.2 Western Approaches to the Solent
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Astronomical Research at Durham
Durham University is one of the UK's leading centres for astronomical research with world-class groups working in a wide range of fields covering the observational, theoretical and instrumentation aspects of astronomy.
September 2014: | Scientist collects prestigious prize for detection of "cosmic ruler" to measure expansion of the Universe |
July 2014: | Durham University astronomers create precision map to calculate amount of dark matter in far off galaxy cluster. |
June 2014: | Durham University named Europe's leading centre for space science researchers. |
June 2014: | Four astronomy group members are listed in the most highly-cited 1% of researchers in Space Science for 2002-2012 (Thomson Reuters ESI). |
May 2014: | Prof Shaun Cole is a joint winner of the 2014 Shaw Prize for his work on cosmological structure with the 2dF galaxy survey. |
April 2014: | European Best Doctoral Thesis Prize for former Durham PhD student Claudia Lagos The 2014 MERAC Prize for the Best Doctoral Thesis in Theoretical Astrophysics has been awarded to former Durham student Claudia Lagos, who undertook her thesis work here at the ICC between Oct 2009 and Sept 2012, under the supervision of Prof. Carlton Baugh and Dr. Cedric Lacey. |
February 2014: | £7.4M award to support astronomy research at Durham University STFC have recently announced the award of a £7.4M grant to support astronomy research at Durham University for 2014-17. This resource will fund research activities within the Centre for Advanced Instrumentation, the Institute for Computational Cosmology and the Centre for Extragalactic Astronomy. |
10 Jan 2014: | Prof Carlos Frenk awarded the 2014 Royal Astronomical Society Gold Medal |
1 Jan 2014: | Prof Ian Smail has been appointed as Chair of the STFC Astronomy Grants Panel |
Durham has the largest number of highly-cited researchers in Space Sciences (which covers research into astronomy and astrophysics) of any institute in Europe and is joint fifth world-wide, according to the most recent league table from Thomson Reuters ESI.
There are 28 academic staff across the combined astronomy groups, with over 100 postdocs, postgraduate students and support and technical staff involved in astronomy research. The majority of our astronomical research is undertaken in the following groups:
Contact Details
Department of Physics,Durham University,
South Road,
Durham DH1 3LE
Tel: 44 (0)191 3343635


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Jada Pinkett Smith didn't make our list of "Sexy Celebs Who Can Go Braless" this morning, but she's further proof that small-chested women can look stunning in v-necks. Her animal-print, polka dot hybrid gown is also beautiful with the red clutch that adds the right pop of color. [L.A., 4/17/10]
Jada, We Didn't Mean To Make You Feel Left Out!
Posted Under: celebrity style, fashion, jada pinkett smith, quick pic


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POSTED: Thursday, October 24, 2013 - 7:18pm
UPDATED: Friday, October 25, 2013 - 6:38am
(CNN) — President Barack Obama on Thursday touted the immigration reforms that the Senate passed in June but were blocked in the House, and called on House Republicans to work with Democrats to get a deal. "This reform comes as close to anything we've got to a law that will benefit everybody now and far into the future. Let's see if we can get it done, and let's see if we can get it done this year," Obama said at the White House.


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Glucose Sensor Reveals Glucose Patterns Around the Clock
If you test your blood glucose regularly, you probably think you have a pretty good idea of how high or low your numbers rise and fall during a typical day and night. However, what if you had 288 blood-glucose readings every 24 hours, instead of only a handful?
Since Medtronic MiniMed's Continuous Glucose Monitoring System (CGMS) was approved by the U.S. Food and Drug Administration three years ago, people using CGMS—which is also known as "the sensor"—have discovered that the avalanche of data reveals surprising patterns.
"The sensor has changed the whole approach to diabetes management," says Scott Lee, MD, of Loma Linda University Medical Center.
CGMS has shown that no matter how dedicated you are to self-monitoring, fingersticks provide only a meager snapshot of a much more complex picture.
"Patients are amazed by the results," says Allen King, MD, director and co-founder of the Diabetes Care Center in Salinas, California. "They have no idea [without CGMS] where their blood glucose is going."
'The Sensor'
CGMS, which is available to patients only under a doctor's supervision, is a small, flexible platinum electrode coated with the enzyme glucose oxidase within a semi-permeable membrane. It is inserted underneath the skin in the hip or abdomen with a needle-like device and is usually worn for three days at a time.
Glucose from interstitial fluid (the clear fluid just beneath the surface of the skin) is converted to an electronic signal. A wire cable from the sensor transmits the signal to a pager-sized monitor that acquires the data continuously.
When the data is downloaded to a computer at the doctor's office or clinic via a com-station, software generates graphs and pie charts that paint a startlingly clear portrait of blood-glucose changes. Thoughtful analysis can then uncover the reasons for excursions—episodes in which blood glucose drifts away from the target ranges—and provide an opportunity to change insulin and medications to prevent them.
Patients using the sensor are frequently disappointed to find that the screen on the CGMS monitor does not display "real-time" glucose values. However, the point of the process is not to provide instant information. The real value of CGMS is the opportunity to study trends over time to form a comprehensive picture.
Who Uses It and Why
Although CGMS seems to be most widely used by people on insulin pumps, it may also be helpful for people with diabetes who use multiple insulin injections and/or oral agents, for teenagers and children, for women who are planning to become pregnant or who are already pregnant, and for people with type 2.
What is the primary reason for requesting the sensor?
"Nighttime," says Mary Harris, RN, BSN, BA, a sensor specialist with Medtronic MiniMed. "Many patients are deeply concerned about blood-glucose changes while they're sleeping, and CGMS shows every rise and fall."
Doctors recommend CGMS in the following cases:
- When a person has a high A1C
- When a person's A1C results don't correspond with traditional blood-glucose self-monitoring results
- When unexplained blood-glucose excursions occur
- When there is an urgent need to control blood glucose, such as during a pregnancy or when trying to determine whether hypoglycemia is a factor in seizures
The device also helps diagnose the presence of gastroparesis—a condition in which nerve damage to the digestive tract causes delayed food absorption. CGMS can also allow people with diabetes to discover hypoglycemia unawareness.
Alan Marcus, MD, FACP, associate clinical professor at the University of Southern California Keck School of Medicine and president of South Orange County Endocrinology, participated in pre-approval studies for CGMS and has used the sensor in his practice for three years now. Marcus believes that even people with low A1C levels are CGMS candidates, as they may be hypoglycemic as much as 20 percent of the day.
Too Much Insulin?
Doctors assessing their patients' management with CGMS are finding that insulin doses are often incorrect.
"We're giving too much insulin," Dr. King observes.
King and Dana Armstrong, CDE, RD, co-founder of the Diabetes Care Center in Salinas, developed a novel approach, nicknamed "tweaking," which involves putting pump patients on CGMS for a week at a time. Patients eat the same foods each day and skip meals as directed on certain days to better assess baseline (basal) insulin. Data is downloaded every morning, and incremental insulin adjustments, or "tweaks," are made each day.
By week's end, according to King, control is near perfect. King and Armstrong are currently working to determine the time period required before another "tweak" is needed.
King found that CGMS data often shows that only half the amount of insulin is required compared to the standard recommendations.
Getting Rid of Hypoglycemia
CGMS has also shown that hypoglycemia is rampant.
"The rate of hypoglycemia is three times as much as we thought," Dr. King reports.
Other doctors using CGMS have made similar discoveries. Dr. Lee says that patients in his practice have used sensor data to reduce their hypoglycemic excursions by as much as 70 percent.
Laura Matarazzo of Aptos, California, an insulin pumper for 12 years, has been on CGMS more than ten times.
"I found that although we thought my basal rates were really good, I was actually dipping low in the early morning," she says.
The Diabetes Control and Complications Trial showed that one-third of hypoglycemic events occurred without symptoms. One CGMS study followed a patient who kept his A1C below 6% but also had severe hypoglycemic episodes. When his CGMS graphs showed drops below 50 mg/dl several times a day without symptoms, the patient immediately understood the urgent need to reduce his insulin.
The graphic representation of data has an impact on overall understanding that self-monitoring lacks.
"A picture is worth a thousand words," Dr. Lee explains. "When patients are actually able to visualize what's going on with their blood glucose, it has a profound effect on their compliance."
The Crucial After-Meal Period
After-meal glucose rises are receiving more attention from clinicians, and CGMS demonstrates the need to dose carefully to cover meals.
Doctors using CGMS are discovering new ways that pumpers can administer boluses to better accommodate meals, especially high-fat meals—pizza being a major culprit—that cause blood-glucose rises hours later.
Some pumpers using dual-wave boluses for meals—an insulin pump function that gives half the meal dose immediately and the other half spread over a specified period of time—have been able to reduce their A1C levels to the 5% range.
Additional Discoveries
Nighttime sensor data has been an eye-opener.
"The sensor shattered an image for me," says Evelyne Fleury-Milfort, NP, CDE, of the University of Southern California Center for Diabetes. "We always thought that almost everyone has low blood glucose at 3 a.m., but we found that a lot of patients have high blood glucose all night."
Others have found that although they wake with a normal blood glucose, their numbers spike high or drop low while they sleep.
Sensor Successes
Garth Borman of Monterey, California, found that CGMS revealed trends he couldn't detect with self-monitoring. Even though he tests 10 to 12 times day, CGMS showed his numbers spiking between tests. Borman says that CGMS data has allowed him to reduce his A1C steadily to around 6.1%.
CGMS allowed Matarazzo to eliminate her early morning hypoglycemia and drop her A1C from 9% to 6.6%.
The Right Attitude for Analysis
Doctors agree that unrecognized trends toward high and low blood glucose are the common theme in CGMS results, and they also agree that discovering these trends is best done in a supportive atmosphere that doesn't blame patients. Physicians experienced in reading CGMS data are not surprised by wild, pre-CGMS blood-glucose swings.
"This is not a test or a grading system," says Dr. Marcus, who encourages patients and doctors to focus on the problems they hope to solve by using CGMS and then look at the data as a tool to solve those specific issues.
"Patients need emotional support to make good decisions about their care," Dr. King adds.
The Emotional Impact
A sensor experience evokes an array of emotions. People are delighted with continuous data, yet frustrated by the lack of "real-time" numbers and the realization that the gadget is only one small piece of the long-anticipated "closed loop" or artificial pancreas.
Harris reports that patients' reactions to their results vary.
"The results are sometimes so surprising their jaws drop," she says. "They're absolutely shocked."
Others are pleased to find that the data corroborates trends they suspected but couldn't confirm with self-monitoring. This knowledge gives them the confidence to make needed changes.
Matarazzo says that it was frightening to see sensor data that showed her going so low while asleep, but she admits that it was a relief to be able to do something about it.
"There's no other way to catch that," she notes.
Nighttime findings are especially surprising. Fleury-Milfort describes individuals who look at their graph and remark, "That's not my blood sugar. I don't go that high [or that low] at night."
Fleury-Milfort asks her patients to do a self-test during the night to validate sensor findings.
Barriers to Wider Adoption
Doctors experienced with CGMS agree that although the cost to the provider is minimal—less than $3,000—in practice the device continues to be underused. Additional barriers have kept it from being more widely adopted.
The biggest remaining obstacle to wider CGMS use may be a lack of awareness and understanding among providers.
Dr. King says that more training is needed for providers to help them interpret results.
Without experience, doctors may find the huge volume of data that is collected to be initially overwhelming and even alarming.
Additionally, providers may hesitate to bring CGMS into their practice because they fear that administering it will be too time-consuming. However, doctors who are using the device now argue that it can save time in troubleshooting management problems and that the real time wasters are traditional doctor/patient appointments to adjust insulin and medications without CGMS data.
Once trained, cost-efficient mid-level providers such as certified diabetes educators can perform most of the tasks of administering CGMS and analyzing results.
The Holy Grail of Perfect Blood Glucose?
Does CGMS make perfect blood-glucose levels attainable? Absolute perfection in glucose numbers may not be necessary or realistic 100 percent of the time, even with continuous glucose monitoring.
"You don't need to get everything perfect to be really safe," Dr. Marcus advises.
Dr. Lee says that using CGMS with patients in his practice has allowed them to reduce their A1C levels to near normal.
"Staying within normal ranges is very achievable with CGMS."
Healthcare providers who are interested in training to interpret CGMS data can contact Dr. Allen King and Dana Armstrong via email at email@example.com. People with diabetes seeking access to CGMS can contact Medtronic MiniMed at (800) 933-3322 to find a provider in their area.
Perfect? Not Yet
Researchers Say Sensor May Give False Readings
If results from a Medtronic MiniMed Continuous Glucose Monitoring System (CGMS) indicate low blood-glucose excursions over-night, can you trust the readings?
The answer could be no, especially if your diabetes is tightly controlled, say researchers who studied seven adolescents and young adults with type 1 diabetes and an average A1C of 6.6%. The research subjects were admitted to the University of Minnesota Clinical Research Center for a round-the-clock study.
When blood-glucose measurements were taken with a laboratory standard glucose analyzer and compared with the CGMS readings, the CGMS readings were lower in 74 percent of the paired tests performed during the 24-hour test period. Readings were also taken with an Accu-Chek Advantage meter, but the glucose analyzer levels were used as the standard during the study.
The average correlation between CGMS readings and glucose analyzer readings during the 24-hour test period was only 0.76, with a trend for the poorest correlation to occur in the patients with the least variability in daily glucose levels.
When the lowest CGMS reading of the night was compared to its paired glucose analyzer reading, the CGMS level was lower in all cases by an average of 38 mg/dl plus or minus 15 percent. In six of the seven participants, the discrepancy was considered clinically significant. In at least four cases, CGMS overnight levels were falsely low in a range that might have resulted in inappropriate reduction of the nighttime insulin dose.
The researchers conclude that more studies should be done on people with varying levels of blood-glucose control, in order to rule out calibration inaccuracies. The CGMS software that directs the calibration of the device may require a wider range of glucose values as input to perform accurately. The CGMS development group has reportedly released a new calibration algorithm with a wider glucose value range that improves accuracy in persons with tight glycemic control. However, researchers also said it is possible that interstitial fluids, which the CGMS measures, lag behind the plasma glucose level.
In the meantime, the researchers urge caution in using overnight readings from the CGMS to adjust insulin dosages.
—Diabetes Care, September 2002
According to an earlier study, Israeli researchers tested CGMS on 11 people (six with type 1, three with type 2 and two without diabetes).
They concluded that "in a real-life setting, the accuracy of data provided by the Medtronic/MiniMed glucose sensor may be less than expected." The researchers added that, to avoid therapeutic errors, "sensor findings should be confirmed by independent means before clinical decisions are made."
Medtronic MiniMed responded by noting that this study used an earlier model of software, which has since been updated.
—Diabetes Care, July 2002
Closing the Loop
In June 2002, at the American Diabetes Association Scientific Sessions in San Francisco, California, Medtronic MiniMed announced the first results of closed-loop trials in five patients.
Each patient had a glucose sensor implanted in the bloodstream near the right atrium of the heart and linked to an implantable pump with an abdominal lead.
When sensor data regulated insulin delivery in this closed-loop system, the subjects' glucose levels were maintained near normal 42.3 percent of the time—approximately twice the effectiveness found in a control group using blood-glucose self-tests only.
Click Here To View Or Post CommentsCategories: A1c Test, Blood Glucose, Blood Sugar, CGMs, Diabetes, Diabetes, Food, Hypoglycemia Unawareness, Insulin, Insulin Pumps, Low Blood Sugar, Meters, Monitoring, Type 1 Issues, Type 1 Issues, Type 2 Issues


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