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Clinical Trials (PDQ®)
Basic Trial Information
Trial Description
Further Trial Information
Eligibility Criteria
Trial Contact Information
Phase | Type | Status | Age | Sponsor | Protocol IDs |
Phase II | Biomarker/Laboratory analysis, Treatment | Active | 18 and over | NCI, Other | CDR0000675211 P30CA022453, WSU-2010-056, 2010-056, NCT01147016 |
RATIONALE: Neoadjuvant chemotherapy for women with stage II-III Her negative breast cancer followed by Her2Bi armed activated T cells (ATCs) may significantly improve the pathologic complete response (pCR) rate at the time of surgery. Arming ex vivo expanded T cells in the laboratory may help the T cells kill more tumor cells when they are put back in the body. Giving combination neoadjuvant chemotherapy followed by laboratory-treated T cells before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed.
PURPOSE: This phase II clinical trial is studying how well giving laboratory-treated T cells after neoadjuvant chemotherapy works in treating women with stage II or stage III breast cancer undergoing surgery.
Further Study Information
- To determine, in a phase II clinical trial of women with stage II-III triple-negative breast cancer, if a regimen of neoadjuvant chemotherapy followed by HER2Bi-armed activated T cells (ATCs) improves the pathologic complete response (pCR) rate at the time of surgery.
- To investigate the association between pCR and clinical responses (disease-free survival and overall survival).
- To determine if HER2Bi-armed ATCs administered after neoadjuvant chemotherapy will modulate the cytotoxicity of lymphocytes in the blood and tumor-infiltrating lymphocytes.
- To determine if there is an association between systemic and tumor site anti-tumor responses.
- To determine if HER2Bi-armed ATCs administered after neoadjuvant chemotherapy decreases the frequency and colony-forming ability of the putative breast cancer stem cells in the tumor tissue at the time of surgery compared to that obtained in the tumor biopsy after chemotherapy.
- To investigate the association between the observed changes in numbers and proportion of CD44^hi/CD24^lo, CD133, aldehyde dehydrogenase activity (ALDH1)-positive cells and the pCR.
OUTLINE: This is a multicenter study.
- Neoadjuvant chemotherapy: Patients receive doxorubicin hydrochloride and cyclophosphamide every 2 weeks for 4 doses. Patients then receive paclitaxel once a week for 12 doses.
- Neoadjuvant immunotherapy: Beginning 3-6 days after the last dose of chemotherapy, patients receive autologous HER2Bi-armed activated T cells (ATCs) IV over 30-60 minutes once a week for 4 weeks.
- Surgery: Approximately 2 weeks after the last dose of HER2Bi-armed ATCs, patients undergo standard surgery.
Tissue and blood samples are collected periodically for correlative immune function tests.
After completion of study treatment, patients are followed up every 8 weeks for 48 weeks and then every 3 months thereafter.
Eligibility Criteria
Inclusion Criteria
- Signed and dated institutional review board (IRB)-approved consent form
- Women of reproductive potential must agree to use an effective nonhormonal method of contraception during therapy
- Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0 or 1 and/or Karnofsky PS of >= 70%
- Diagnosis of invasive adenocarcinoma of the breast made by core needle biopsy
- Palpable primary breast tumor measuring >= 2.0 cm on physical exam or imaging
- Patients with stage II-IIIA breast cancer that is HER2-negative by immunohistochemistry (IHC) (0-2+) or fluorescence in situ hybridization (FISH) (HER2/chromosome enumeration probe [CEP]17 amplification ratio < 2.2) for whom definitive surgical treatment after "third generation" neoadjuvant chemoT is planned; Patients with HER2 (3+) cancer by IHC that also demonstrate a FISH ratio <2.2 are also eligible. Estrogen receptor (ER) or progesterone receptor (PR) status can be positive or negative; the receptor status needs to be recorded
- Patients may have lymph node positive or negative disease, as long as they have clinical stage II or IIIA breast cancer; patients may have the lymph nodes assessed by any method deemed appropriate by the treating physicians, including pre-neoadjuvant therapy sentinel lymph node biopsy
- Patients must discontinue sex hormone therapy prior to registration, e.g. birth control pills, hormonal replacement therapy
- Absolute neutrophil count (ANC) must be >= 1200/mm^3
- Platelet count must be >= 100,000/mm^3
- Hemoglobin must be >= 9.0 mg/dL
- Total bilirubin must be =< the upper limit of normal (ULN) for the lab unless the patient has a grade 1 bilirubin elevation (> ULN to 1.5 x ULN) resulting from Gilbert's disease or similar syndrome due to slow conjugation of bilirubin; and
- Alkaline phosphatase must be =< 2.5 x ULN for the lab
- Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) must be =< 1.5 x ULN for the lab
- Alkaline phosphatase and AST/ALT may not both be > the ULN; for example, if the alkaline phosphatase is > the ULN but =< 2.5 x ULN, then the AST/ALT must be =< the ULN; if the AST/ALT is > the ULN but =< 1.5 x ULN, then the alkaline phosphatase must be =< ULN
- Patients with either skeletal pain or alkaline phosphatase that is > ULN must have a bone scan showing they do not have metastatic disease; suspicious findings on bone scan must be confirmed as benign by x-ray, magnetic resonance imaging (MRI), or biopsy
- Patients with AST/ALT or alkaline phosphatase > ULN must have liver imaging that does not demonstrate metastatic disease
- Patients with AST/ALT > ULN must have negative hepatitis studies
- Patients with stage II disease and clinical suspicion for metastatic disease based on reported symptoms, physical examination findings, or laboratory abnormalities must have staging studies demonstrating no evidence of metastatic disease (with exception of axillary lymph nodes or mammary nodes); patients with stage IIIA disease must have staging studies demonstrating no evidence of metastatic disease (with exception of axillary lymph nodes or mammary nodes), even if asymptomatic with normal physical examination and laboratory values; such staging studies must include: chest imaging (chest X-ray, computed tomography [CT], or MRI), abdominal/pelvis imaging (CT or MRI), and bone imaging (bone scan or positron emission tomography [PET]-scan); abnormalities that are indeterminate and too small to biopsy should be followed with further imaging, as appropriate, but do not exclude patients from the study; abnormalities that are suspicious and large enough to biopsy exclude patients from the study, unless a biopsy is performed and is negative for metastatic disease
- Serum creatinine =< 1.5 x ULN for the lab
- Pre-entry core biopsy with sufficient material for correlative studies
- Left Ventricular Ejection Fraction (LVEF) >= 50 % (by multigated acquisition scan [MUGA] or echocardiography)
Exclusion Criteria
- Tumor determined to be HER2-positive by immunohistochemistry (3+) or by fluorescent in situ hybridization (HER2/CEP17 amplification ratio >= 2.0)
- Tumors clinically staged as T4 or N3
- Definitive evidence of metastatic disease with exception of axillary lymph nodes or mammary nodes
- Synchronous bilateral breast cancer (invasive or ducal carcinoma in situ [DCIS])
- Treatment including radiation therapy, chemoT, biotherapy, and/or hormonal therapy for the currently diagnosed breast cancer prior to study entry
- Any sex hormonal therapy, e.g., birth control pills, ovarian hormonal replacement therapy, etc. (These patients are eligible if this therapy is discontinued 1 week prior to registration)
- Prior history of invasive breast cancer (Patients with a history of DCIS or lobular carcinoma in situ [LCIS] are eligible)
- Prior therapy with anthracyclines for any malignancy
- Other malignancies unless the patient is considered to be disease-free for 5 or more years prior to randomization and is deemed by the physician to be at low risk for recurrence; patients with the following cancers are eligible if diagnosed and treated within the past 5 years: carcinoma in situ of the cervix, carcinoma in situ of the colon, melanoma in situ, and basal cell or squamous cell carcinoma of the skin
- Known cardiac disease that would preclude the use of anthracyclines; this includes:
- Angina pectoris that requires the use of anti-anginal medication
- History of documented congestive heart failure
- Serious cardiac arrhythmia requiring medication
- Severe conduction abnormality
- Valvular disease with documented cardiac function compromise; and
- Uncontrolled hypertension defined as blood pressure (BP) that is consistently > 150/90 on antihypertensive therapy at the time of registration (Patients with hypertension that is well controlled on medication are eligible)
- History of myocardial infarction (MI) documented by elevated cardiac enzymes with persistent regional wall motion abnormality on assessment of left ventricular (LV) function (Patients with history of MI must have an echo instead of/in addition to a MUGA to evaluate LV wall motion)
- Symptomatic peripheral vascular disease
- Sensory/motor neuropathy >= grade 2, as defined by the National Cancer Institute (NCI)'s Common Terminology Criteria for Adverse Events Version 4.0 (CTCAE v4.0)
- Other non-malignant systemic disease (cardiovascular, renal, hepatic, etc.) that would preclude treatment with any of the treatment regimens or would prevent required follow-up
- Chronic ongoing steroid use at the time of registration for any condition (such as asthma, rheumatoid arthritis, etc)
- Administration of any investigational agents within 30 days before study entry
- Pregnancy or lactation at the time of registration
- Psychiatric or addictive disorders or other conditions that in the opinion of the investigators would preclude the patient from complying with the study protocol.
Minor changes from these guidelines will be allowed at the discretion of the research team under special circumstances. The reasons for exceptions will be documented
Trial Lead Organizations/Sponsors
Barbara Ann Karmanos Cancer Institute
National Cancer InstituteLawrence Lum, M.D. | Principal Investigator |
Trial Sites
Michigan | |||
Detroit | |||
Barbara Ann Karmanos Cancer Institute | |||
Clinical Trials Office - Barbara Ann Karmanos Cancer Institute | Ph: 800-527-6266 | ||
Zaid Al-Kadhimi | Sub-Investigator | ||
Rouba Ali-Fehmi, M.D. | Sub-Investigator | ||
Lydia Choi, M.D. | Principal Investigator | ||
Abhinav Deol, M.D. | Sub-Investigator | ||
Neb Duric, Ph.D. | Sub-Investigator | ||
Lawrence E. Flaherty | Sub-Investigator | ||
David Gorski, M.D., Ph.D. | Sub-Investigator | ||
Sayeh Lavasani, M.D. | Sub-Investigator | ||
Michael Simon, M.D., MPH | Sub-Investigator | ||
Archana Thakur | Sub-Investigator | ||
Link to the current ClinicalTrials.gov record.
NLM Identifer NCT01147016
ClinicalTrials.gov processed this data on October 20, 2014
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Summary: Chinua Achebe's first novel portrays the collision of African and European cultures in people's lives. Okonkwo, a great man in Igbo traditional society, cannot adapt to the profound changes brought about by British colonial rule. Yet, as in classic tragedy, Okonkwo's downfall results from his own character as well as from external forces. Contributors to this anthology include Assia Djebar, Abdurazak Gurnah, Kojo Laing, Daniel Mandishona, Ben Okri, and Tijan Sall ...show moreah. The volume contains twenty "short stories written between 1980-1991. They are divided by region: five stories from Southern Africa; two from Central Africa; five from East Africa; two from Northern Africa; and six from West Africa." (SLJ) This collection of essays and speeches by the Nigerian novelist begins with an analysis of bigotry in Joseph Conrad's Heart of Darkness and "ends with a tribute to James Baldwin. Along the way there are speeches on broad topics, such as 'The Truth of Fiction' and 'Thoughts on the African Novel', a personal tribute to Christopher Okigbo, and passing reflections on the present needs of his own society." (Times Lit Suppl) Bibliography. Index. This is Chinua Achebe's classic novel, with more than two million copies sold since its first U.S. publication in 1969. Combining a richly African story with the author's keen awareness of the qualities common to all humanity, Achebe here shows that he is "gloriously gifted, with the magic of an ebullient, generous, great talent." -- Nadine Gordimer ...show less
Edition/Copyright: 96Filter by: All (45) | New (6) | Very Good (5) | Good (27) | Acceptable (7)
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subset: commoncrawl


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Live Stats Listen: Mix 101.3 FM Watch: OVCDN UTM Game Notes
MARTIN, Tenn. – The University of Tennessee at Martin women's basketball team will look to continue its winning ways with an Ohio Valley Conference road matchup at SIU Edwardsville on Saturday, Feb. 8. Tipoff from the Vadalabene Center is schedule for 4 p.m. as both teams join in the Pink Zone to help create awareness and raise funds for breast cancer research.
The Skyhawks (17-6, 10-0) are off to their best start in the program's conference history, winning their first 10 games and holding an overall .739 winning percentage. The league's leading scoring offense tallied 87 points against Eastern Kentucky, the most points allowed by the Lady Colonels on the season.
Offensively the night belonged to senior guard Heather Butler who tied the Skyhawks program record with 44 points on 12-of-19 shooting from the floor and 14-of-15 from the free throw stripe. Two other Skyhawks scored in double figures as Jasmine Newsome tossed in 16 points and six assists while Ashia Jones tallied 12 points to go along with five rebounds and two blocks in just 24 minutes of play.
SIUE (6-17, 2-8 OVC) snapped a four-game losing streak with a 59-54 victory over NJIT on Monday evening. Two players scored in double figures for the Cougars, led by the play of freshman Micah Jones who tallied 18 points, nine rebounds and six steals. Ashley Capotosto tallied 10 points for the Cougars to round out the team's double-digit scorers.
The Skyhawks own an 8-5 advantage in series history, winning the most recent matchup on Jan. 25 in Martin 111-72. The team's 111 points ranked as the second highest in program history and the most ever scored at home. Six players scored in double figures, led by the play of the freshman tandem of Jones and Elizabeth Masengil who combined for 36 points.
Fans can watch the game live, free of charge, on the OVC Digital Network by clicking on the link at the top of the webpage. Chris Brinkley (play-by-play) and Alex Boggis (color) will be live on the call locally on Mix 101.3 FM. Live stats for the game will also be provided at the link above.


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On 02/13/2013 09:37 AM, drew Roberts wrote:
Well, the Pengiun folks are breaking a law, since the things they copy
are public domain. They are not infringing any copyrights, and are not
making use of someone's property illegally. Are they "ripping people
off?" I don't know. Go ask their customers if they knew they could
have gotten all of that legally for free.
>From what I've seen, people buy pirated DVDs because they either don't
have a DVD burner, or they believe that it is safer to buy it for cash
at some flea market where there is no paper trail leading to them.
My bands, CD projects, music, news, and pictures:
My blog, with commentary on a variety of things, including audio,
mixing, equipment, etc, is at:
Staat heißt das kälteste aller kalten Ungeheuer. Kalt lügt es auch;
und diese Lüge kriecht aus seinem Munde: 'Ich, der Staat, bin das Volk.'
- [Friedrich Nietzsche]
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Hosting provided by the Virginia Tech Department of Music and DISIS.


text:
Items Tagged with 'creative'
Dillon Tardiff
Conference-Crashing Gen Y Advocate
'This industry is one of the world's best-kept secrets.'
Read More
The THINK Conference
'Tolerate Failure'
Startup guru suggests leaders 'talk last' if they want to encourage employees to innovate.
Read More
Top-Notch Marketers: Part II
Marketing: The Blessing and the Curse
Marketing is constantly changing, requiring marketers to change with it.
Read More
Leading Edge
Pixar Animation Studios encourages imagination, inventiveness, and collaboration. What can CUs learn from its approach?
Read More


text:
My Profile
MIAMI, Florida
Member since May 2006
Flag This ProfileFlag as Inappropriate
Reviewed Monster Muffaletta
Jan 5, 2013 in Food Network Community Toolbox on FoodNetwork.com
"This was an awesome recipe!!! My 7 year old loved loved the olive salad!! We had some left over and put it on crustini chibatta bread--delicious!! It is also easy enough to let the kids help prepare the sandwich! We added fresh romaine for a little crunch!! Big hit we will be making this over and over!!! Now the kids are always looking for Sandwic""


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Fri, Oct 19, 07 at 17:53
I have a zucchini/carrot cake that I have always baked in a 9 x 13 inch cake pan. I have one of those flexible ('plastic') bundt pans that can be used either in the oven or microwave & was wonderng if I could bake this cake in the bundt pan also .. or are recipes calculated for specific size pans? I'd hate to ruin the cake but I thought once in awhile the cake would look better in the bundt pan.
Would appreciate any ideas! -vieja |
Follow-Up Postings:
I don't see why not. You'll probably have to adjust the baking time, but that's not hard to figure out. Just test the cake for doneness at various intervals around it's normal baking time. |
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Nick Jonas Is Single!
Women of the world, rejoice! Nick Jonas is officially on the market!
Nick, 16, appeared on 104.3 MYfm's 'Valentine in the Morning' show to discuss many topics—among them, the sudden popularity of the acronym "OMJ" (tweener shorthand for "Oh, my Joe!").
More importantly, he divulged his current relationship status, and it's good news for the young ladies out there.
When host Sean Valentine told Nick—who's been romantically linked to Miley Cyrus and Wizards of Waverly Place star Selena Gomez—that he'd heard Jonas is currently unattached, the littlest JoBro at first replied coyly, "That's the rumor I'm hearing."
But Scott Valentine can smell a hot story from a mile away. Or at least within the confines of his broadcast studio. So he pressed on, offering Jonas an opportunity to tell his listeners the truth.
Better sit down while you read the following sentence...
"Absolutely; yes, I'm single," Jonas 'fessed up.
Don't believe us? Listen to the shocking admission here.
So there it is, people. Nick. Jonas. Is. Single!!!!
Is that an earthquake we just felt, or the stampede of eager females nationwide?


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I am very interested in this game. Something different with less violence and a great story and provoking emotion. This is the impression i get from reviews. I read the puzzles aren't real hard but still interesting and graphics look great. Gamespot said he finished the game in 6 hrs another site said 10 hrs.
whoever bought valiant heart please give your review here.
- ewalthour
- Member Since: August 24, 2013
- Posts: 764
- hrt_rulz01
- Member Since: December 2, 2006
- Posts: 6421
- Forum Posts: 6421
- Followed by: 18
- Reviews: 0 Stacks: 0
I have yet to finish it, but so far I'm really enjoying it. It's not challenging, but I don't mind that at all. It has great style, and definitely hooks you emotionally. I think it's a safe bet!
- ewalthour
- Member Since: August 24, 2013
- Posts: 764
- ewalthour
- Member Since: August 24, 2013
- Posts: 764
Well the he'll with those who didn't response witg providing impressions of thr game if you could have. I like the art style and puzzles and the history. Yes the game isn't combat oriented which I am cool with. I just started and playing as freddy blowing up the bridge. I am going to sleep.
So far I am glad I purchased it after reading a myriad of reviews that were very good. I like emotional games and not enough of them latelybare made.This makes me excited for sherlock Holmes with the solving puzzle or clues type game with logical thinking. Oh and the music score is fantastic. So far I give It a 8/10 for a indie style, mostly non interactive non-violent game.


text:
Siegfried Lenz, one of the great writers of German post-war literature is dead. He died on 7 October 2014, surrounded by his family. He was 88 years old.... more
Die Welt 04.07.2008
Wieland Freund has a charming conversation with Jonathan Franzen, who seems to be lingering in Berlin for the opening of the American Embassy, and speaks about the advantages of the German language and literature, and about Berlin: "It is magnificent to come to a city ...
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I just have to vent. The rabbits have pretty much desimated eight rose bushes in one of my beds, plus numerous others in several other beds. I used liquid fence, but it still did not stop them. They chewed down large old bushes as well as new ones. They even cleaned out my climbing hydrangea, which has been taking forever to establish. Tney have eaten barberry bushes, wiegelia, euonymous and who knows what else. And my yard is FULL of rabbit poop. I hate rabbits! |
Follow-Up Postings:
- Posted by crzy4flowers 7GA (My Page) on Tue, Mar 25, 08 at 15:51
I am so sorry for you trustmissy! I have one really big rabbit that hangs around my back yard. He is too too funny. He only poops in one place and it's an old tree stump. He just piles in on. It is hilarious. I told him he could stay as long as he eats ONLY grass and so far he has behaved. I hate to hear that yours are most definitely NOT behaving! I'm praying mine will continue to be happy just eating grass. April |
- Posted by mgleason56 5b (My Page) on Tue, Mar 25, 08 at 16:35
I know how you feel! I have now gone to great lengths to protect my rarer bushes from the rabbits after they also decimated an entire area 2 years ago. I wish my DW & kids could be convinced to try rabbit stew! |
I SO know how you feel. I have a terrible rabbit problem. They eat my roses and they especially love my lilies! I,too,have tried everything on the market with no relief. I now must use chicken wire around anything I value. Let me say, this does not make for the beautiful garden I strive for. Please let us know if you find anything else that works. You have my sympathy.....Lesley |
- Posted by athenainwi z4b/5 WI (My Page) on Tue, Mar 25, 08 at 19:19
The only thing that works for me is a very secure fence and two dogs, and I still get some damage. Rabbits are very hard to discourage and they love roses. I use Liquid Fence in the front yard which isn't fenced, but it needs to be reapplied often. |
I have a gazillion of star of Bethlehem and rabbits love its tender leaves. I usually cover these bulbs with a "bird net" after noticing that they were eaten to the ground. Last year rabbit(s) ate my baby Quietness to the ground but happy surprise, it came back from its roots and since that it was protected with a chicken wire ring. Another favorite of rabbits is Delphinium (I often read that Delphiniums are poisonous but it seems, not to rabbits) so my Dowdeswell Delphiniums also have ugly chicken wire rings around them after they reemerged from their roots. I've never noticed that rabbits were interested in lilies. In any case, this year when I let the rabbits feed on star of Bethlehem again and again, they didn't hurt the roses. Needless to say, I had no Star of Bethlehem blooming. However, I doubt that my rabbit issue can be compared to many of you; we probably have only a few. |
heres a site to get some Rabbit Scram to stop them from eating up every thing.I am not bothered with rabbits eating up everything,I am bothered with deer eating up my roses and daylilies,and this deer scram works. http://www.deerscram.com/ Jean |
- Posted by jerseywendy z6 NJ (My Page) on Wed, Mar 26, 08 at 7:10
I can very much relate, and have learned to hate wild rabbits with a passion. Liquid Fence helps a lot, but I have to reapply it often. My (live) rabbit trap has only caught a single one of those rose munchers, but the sling shot my son made has worked wonders. :) --- |
I feel your pain! Last year I had a constant struggle, and felt that putting in new plants and/or roses was just putting in rabbit food. All my roses were/are enclosed with rabbit fencing or chicken wire---not a pretty sight, but it's better than chewed roses, and the foliage eventually covers the cages. A nursery advised weekly spraying with Liquid Fence, which helped a lot. Then a pair of bobcats moved into our Park and the rabbit population went down dramatically! This year I doubled the dose (per gallon) of Liquid Fence (it didn't damgae the plants at all) at the initial spraying, and have continued the weekly spraying with the prescribed dose. Voila! No chewed roses------Yet! Hang in there, and good luck. Beth's mom |
What was I thinking, or not as usual. What a perfect gift, sling shots to the girls next door who lost a floppy eared waabbit. I have been reluctant to set snares because of the girls. I had best talk with their dad first, but what a perfect solution. Too bad they are not boys. Boys like to kill stuff at that age. Perhaps not. I do not like guns after Korea. Ill eagle in the city anywho. I thought about those plastic double sided pads of spikes, but I do not always use knee pads. Ouch! I wish I could afford a paintpall gun. It would mark some targets for our local owl. He does quite well on it's own but ---. We live close to a park which is a waabbit generator no matter how many I encourage to move on. The spray gets pretty expensive in short order. No good solutions. The sling shot idea is worth kicking around. Thanks! F.L. |
- Posted by minnepiper 4a (My Page) on Wed, Mar 26, 08 at 12:07
i chicken wired about 20 roses last oct. the bunnies still pruned them, but only to the top of the wire. |
- Posted by simonne uk(firstname.lastname@example.com) onMon, Jun 14, 10 at 17:49
I have had the unfortunate miss-fortune of looking on here for help regarding my two pet rabbits eating my plants, even though they pain me sometimes and yes! I joke to about making a rabbit stew...regardless, I love them dearly like I love all nature. SLING SHOTS? I am discusted at reading how many people think it's a good idea to harm any part of nature in-humainly! I feel sick of the thought of some poor creature being injured. Hunters use guns! or maybe a dog or you could buy a cat and let nature take it's course? A more humain way is fox urine, Liquid Fence. TOO EXPENIVE? A mixture of garlic, onion, chilli powder and pepper. This works a treat. If nothing else fails. MOVE FROM THE COUNTRY SIDE YOU SICK #**#*##! |
- Posted by slowcookedwithonions (My Page) on Mon, Nov 1, 10 at 3:25
Hi from Oz, Here in Oz rabbits are a pest. Landholders have a requirement to keep numbers down. Not to mention the destruction caused by the warrens. I personally would not endorse the use of a slingshot- what happens if you only maim the animal? and it dies a slow lingering death. No here in Oz the options would be Snare, Gun, Ferret, hunting dog, netting, CO (exhaust fumes hosed down a warren with all openings sealed), or traps. In USA i expect that shooting is not possible neither ferreting, dogs ,netting nor C0. So that leaves snaring , which is an excellent way of capturing & disposing of troublesome pests. A well placed snare that is checked 2-3 times a day ,maybe in a hole in a fence could just be the go. Incidentally to keep rabbit numbers low you need to remove 85% of offspring. A slow cooked stew with wild rabbit is excellent- very little fat and plenty of protein. Also rabbit droppings make excellent manure or compost (at a cost to your plants) |
- Posted by professorroush 5B (My Page) on Mon, Nov 1, 10 at 10:02
Hav-A-Hart traps; worked well for me....not so well for the area across town where I set them free again. |
Here is a link that might be useful: Garden Musings blog
- Posted by karl_bapst_rosenut 5a, NW Indiana (email@example.com) on Mon, Nov 1, 10 at 12:40
I use a very quiet pellet gun and bury the critters near a rosebush. They make great fertilizer. If one uses a pellet gun, be careful as some have the power of a 22 rifle. Aim towards the ground to avoid wayward pellets. |
My pet rabbit is a beloved menace, so I both feel your pain and am appalled that the cute little guys have pellets and rocks coming at them...these are the plants I have noticed he doesn't care for (much): Hibiscus, Allysum (after he nibbled a few he lost interest), Oriental Poppies, Citrus trees, Lavender, Salvia, Nasturtium (only likes the dead leaves), Tomatoes (weird right?), Squash. He does love the rose bush but only eats the leaves and flowers, so once the bush got tall enough he left it alone, only eating the lower leaves and shoots. Hope this helps! |
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While the series has taken a beating over the past few years, it showed some promise with its last installment, but even that excitement was curtailed by the franchise showing its age. For whatever reason, the creative forces behind the Saw films have never upped the ante or expanded the world in any way. That might be something fans complain about as forced with other sequels, but heading back into the same dank squalor to hear the old familiar voice on the tape recorder is a little faulty and repetitive. Fortunately, the new teaser trailer for the seventh installment in the horror series shows some promise that the producers are thinking outside the box by putting someone in it.
Cast List for 'Saw 7′ May Contain Spoilers
Movie News By Scott Beggs on April 26, 2010 | Be the First To CommentDiscuss: The 'Saw' Series Might Just Be Ending
Movie News By Scott Beggs on February 9, 2010 | Comments (10)SDCC: Saw VII in the Works, New Saw VI Poster Revealed
In Development By David Baxter on July 24, 2009 | Comments (3)Absolute shocker of the day, deals are in place and Saw VII is greenlit. In other shocking news, bears shit in the woods.
Neil Miller
Scott Beggs
Rob Hunter
Kate Erbland
Christopher Campbell


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LLRX writes "
Sabrina I. Pacifici documents federal and state resources that address the proliferation of ID theft and online fraud, including current law and pending legislation, as well as consumer advocacy guides and selected news. New on LLRX.com for February 15, 2003 at Identity Theft: An Annotated Bibliography of Federal, State, Consumer and News Resources "


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Ekman Garden Resort
Categories: Accommodation > Resort
Address: 39/2 Moo 5, Sao Phao, Sichon, Nakhon Sri Thammarat 80120 Thailand See map
0 reply, 2,838 viewed
Ekman Garden Resort is a family-run resort priding itself on offering guests a peaceful and friendly atmosphere, situated a 30 minute drive from the Samui ferry pier. The resort has eight rooms on the ground floor which feature a patio and four rooms on the second floor with a balcony. Facilities include a swimming pool, restaurant, spa and parking, while activities on offer include shopping and local sightseeing tours. Snorkelling and boat trips to nearby islands can be arranged.
- Open days
Monday, Tuesday, Wednesday, Thursday, Friday, Saturday, Sunday
Input price range
1,150 - 3,825 Baht/Day or 38 - 128 USD/Day
Remark: "Star" of accommodation is based by Hotel Association of Thailand. If the accommodation are not listed in Hotel Association, we will use the star which is announced in the websites of accommodation.
- Address
39/2 Moo 5, Sao Phao, Sichon, Nakhon Sri Thammarat 80120 Thailand
- Phone number
+66 (0) 7536 7498 +66 (0) 7536 7566
- Mobile number
+66 (0) 8195 82493
- Email
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If Britain ever wants any of my tourism dollars you'll have to restaff those curry places fast. Indigenous ethnic food forces are what brought us Taco Bell. We don't want to go down that dark road again.
MOST OECD countries generally get two types of immigrants, low-skilled and high-skilled. Many natives are unenthusiastic about the prospect of skilled or unskilled immigrants, but they can be especially resistant to the unskilled.
It is well known that wealthier countries often face shortages of unskilled labour willing to do the more unpleasant jobs, so they need more unskilled migrants. But it's been a fairly new development for many OECD countries to also target skilled immigrants (Australia and Canada being a notable exception). Targeting skilled foreigners has become much more popular in Europe and Britain in the last decade. Some countries have even begun to target skilled workers who plan on starting a new business. Pro-immigration policymakers get dewy-eyed at the sight of a Silicon Valley immigrant who starts a tech firm which provides growth, prosperity and jobs.
But when it comes to entrepreneurial immigrants most are actually unskilled. Unskilled immigrants often have a rough time assimilating, they have higher rates of unemployment and earn lower wages. Many end up starting their own business (small shops, restaurants, laundries) because they have trouble finding regular work. The economic benefit of these firms is often discounted, but they do generate a non-trivial amount of economic activity. They also provide employment for other unskilled foreign workers and a greater variety of low cost goods and services to natives.
We may underestimate the extent to which we've come to rely on those goods and services. Andrew Leonard points us to the shortage of curry chefs over the last year in Britain, not helped by tougher visa restrictions (from March 2008):
Tightened immigration requirements in the U.K., set to kick in November, will require that immigrants from the subcontinent, hitherto brought in on sponsored visas to work as cooks in the thousands of Indian restaurants that are the U.K.'s most delicious hangover from empire, must now speak fluent English and possess a "high-level" cooking certificate.
The curry-chef shortage has resulted in the closings of curry houses all over Britain. Skilled workers are generally regarded as highly educated, but this just goes to show that the definition of skill may need to be broadened.
Still, leave it to a Conservative MP to say that rather than import more curry chefs Britain needs to develop "our own indigenous curry workforce".


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GOD'S WORD Translation (GW) | New International Version (NIV) |
63 The men who were guarding Jesus made fun of him as they beat him. | 63 The men who were guarding Jesus began mocking and beating him. |
GOD'S WORD® is a copyrighted work of God's Word to the Nations. Copyright © 1995 by God's Word to the Nations. All rights reserved. Used by permission. (God's Word Translation -Online Bible) | Scripture quoted by permission. Quotations designated (NIV) are from THE HOLY BIBLE: NEW INTERNATIONAL VERSION®. NIV®. Copyright © 1973, 1978, 1984 by Biblica. All rights reserved worldwide. (New International Version Bible Online) |


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About Sketch Fest ~ The History of Sketch FestLog In or Register Registration and login are optional! | Sketch Fest #59: Sketches ~ Prompts
Finished Work Available Sketches Previous Sketch Fests |
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Smileby AnonPrompt: Shapeshifter Drifter Smile |
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The Cavision RS15SP-2 is a shoulder pad accessory for 15mm rod support systems. This device connects to the lightweight support system and offers a shoulder support for camera stability.
- Convenience
- Adjustable to fit different shoulder widths
- Includes two tilt controls
- Constructed primarily out of ABS material to reduce weight <
- Compatibility
- The Universal design allows this device to work with most handheld sized camcorders.


text:
What does ATL mean in Laboratory?
This page is about the meanings of the acronym/abbreviation/shorthand ATL in the Medical field in general and in the Laboratory terminology in particular.
Accredited Testing Laboratory
Find a translation for ATL in other languages:
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Use the citation below to add this abbreviation to your bibliography:
"ATL." Abbreviations.com. STANDS4 LLC, 2015. Web. 1 Feb. 2015. <http://www.abbreviations.com/term/1446286>.
ATL also stands for:
- Above Tha Law
- Above the Law
- Above the Line
- Accelerated Tariff Liberalization
- Accessible Travel And Leisure
... and 38 more »
Nearby & related abbreviations:
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text:
Sun, Sep 5, 10 at 8:42
Today is Calamity's Birthday. Let's all send her oour best wishes. I hope you have a great day Jane and lots of birthday love. |
Follow-Up Postings:
- Posted by slowmedown (My Page) on Sun, Sep 5, 10 at 9:53
Ditto!!!!!!!!!!!!!! and love you very much. |
- Posted by wackyweeder (My Page) on Sun, Sep 5, 10 at 10:19
Happy Birthday you crazy woman! |
- Posted by calamity_j (My Page) on Sun, Sep 5, 10 at 12:53
Ahhh, Thanks Everyone! I plan to enjoy the day by installing my GOG!Glad I got the day off from work! You are all soooo SWEET! And I love you all! |
- Posted by nanatricia (My Page) on Sun, Sep 5, 10 at 18:49
Hey I hope you had a great Birthday!! |
- Posted by shrty411 (firstname.lastname@example.com) on Sun, Sep 5, 10 at 19:38
Happy Birthday! Hope you had a wonderful day! |
Happy Birthday! |
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text: I read this somewhere online. However, the methods seemed awfully complicated... and it said you couldn't use a treadmill. I dunno. However, I was wondering how many people here use High Intensity Interval Training- and do you feel it is really more effective than steady cardio? I am thinking of trying it. But, I haven't done it before. Would it be okay if I just ran until I couldn't run anymore, and then powerwalked until I had receovered? Or do I really need to time myself? How long should I do it for? I really feel like I need to take my workouts to a more intense level. I really want to get the biggest bang for my buck when it comes to exercise, ya know? I would LOVE insight on this from people who have done it.


text:
Break Up Quotes, Sayings about break ups - Page 35
Its hard to say goodbye, when there was never a hello! :(
For females, remember, an ex boyfriend or husband is an ex for a reason.
You never stop loving someone, you just learn to live without them.
If you love him you would get over him and let him live his life happily…!!
It's hard to move on and harder to forget, but the hardest thing… Is to admit she's still the best.
When the heartache is over, I know I won't be missing you!
I've honestly tried to let you go, I've honestly tried to forget you, I've honestly tried not to think of you but I honestly can't cause I honestly don't want to.
Wish I didn't know now, what I didn't know then.
Love hurts, but no matter what happens, the sun still shines, time still passes, and life goes on
When you see him with his new girlfriend your eyes fill up with tears because you love him so much and you wish he knew…
I don't hate you for breaking my heart…I hate my heart for breaking over you!
You make me Happy. Sad. Excited. Angry. Upset. Ecstatic. Humiliated. You make me everything I can be. Your brought joy into this life of mine, but left with more than that. I've changed and I don't know if it's good. I've become stronger, and wiser. Yet unhappiness and dread lurk inside of me. You may not believe it, but I loved you, or at least thought I did. Now I don't know how I can put it but no matter how much I try to forget, I never will. Because unlike you, forever and always meant something to me.
There is no such thing as letting go, there is just moving on and forget.
How do you get over someone you never really had?
What hurts the most is the fact that all these memories mean everything to me.. And they mean nothing to you at all.
Breaking up hurts, But in the end, You always remember that's what made you stronger.
It hurts when she says don't expect anything from me…
Break- ups aren't that bad, they help us. If they break- up with you it means that they never loved you. And if you break- up with them then you know that they're not the one. This doesn't make them hurt any less but it makes you release that they help you find the right person for you.
You tell me to move on, but where do I move to when I belong with you.
It's Not How Long You Spend With The Person. But, The Memories You Created With Them, That Will Leave An Impression On Thier Life And Yours As Well.
Change is always for the best, even tho when you may be to blind to realize it at first; but in the end you will see how much better off you truly are.
Move On, easy word to say, but the hardest thing to do.
Everyone falls n love at least once and everyone is destined to get their heart broken which only makes them stronger for the next obstacle.
Sometimes the hardest part about love is realizing you really don't know how to. You give everything you've got but nothing comes back. This is just for the guys who want to love but can't. I don't know why I can tell someone I love them but the moment they say it back I run away. All I know is that if you don't love some one or you know that some one doesn't love you. By staying in that relationship you're only making life more complicated than it has to be. Pain is a part of life. That's why god gave us logic to deal with it. We are human our minds are never made up.
He said lets just be friends. It broke my heart and I cry over him. I just hope one day he will feel the pain he caused me.


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#31642 of 0 points
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Lib Technologies Skate Banana BTX Snowboard - Assorted Bananas
Hey im buying my first board/park board....
Hey im buying my first board/park board. I have done alot of research and I have come down to two boards that iv heard good things about. I need somthing that will do good on jibs, in park, and on the pipe. Im looking at either the skate banana or the Ride dh2.4, i have heard great things about both but my concern with the skate banana is that its not good on pipe which would be a issue. What would you recommend I do, or is there a better board I didnt mention that I should check out? also what size would you recommend for me? im 6ft 165lbs and wear a 13 boot. Last but not least I have some old flow bindings, would that be fine to stick on my new park board?
0 Answers


text:
Follow-Up Postings:
- Posted by Michelle1973 (My Page) on Fri, Jun 6, 14 at 10:35
Also....I want to do a shiplap on the ceiling in the living, dining, and kitchen. Any suggestions on using faux beams with it? Which direction should the beams run? Not sure I want them to run in both directions as I want to avoid the coffered look. |
I love it....Great house! |
Hi Michelle1973, I think the elevation looks very charming and not farmhouse-y. Hopefully others will weigh in on what you might incorporate in terms of Craftsman details. Perhaps one thing to address is roof pitch? The Craftsman homes I'm used to seeing have a shallower pitch (but then again we don't see snow here). I think your floorplan is quite nice. One picky thing -- if it were mine, I probably would prefer a more direct alignment of the kitchen/living/dining areas. It's great that you are thinking about the ceiling treatment now; with shiplap it will be easier if your joists are running the right direction. Also useful to consider your joist placement if you are planning to use recessed lighting. Good luck! |
Here is a link that might be useful: Craftsman
This post was edited by Oaktown on Fri, Jun 6, 14 at 19:10
I love it. |
The shed dormer is definitely craftsman. Use some tapered columns and some detailing at the peak of the gables. The link I posted might give you some ideas. I plan on incorporating many of these details into my plan. |
Here is a link that might be useful: Craftsman Style
I can see why you love it! So my favs are the shed dormers, window sets and your office off the kitchen. Great location. I also like how you configured the mud entrance - lockers and easy access to the kitchen. And the privacy you have at the master beds room entrance (we missed that with ours). Oh and those kitchen windows! Two Thumbs up! Do you have plans for that angled garage space? |
- Posted by Michelle1973 (My Page) on Sat, Jun 7, 14 at 21:24
Wow, thanks for the positive responses! We are very excited. Autumn, we don't have garage elevations yet...she's working on that next. When we sign off, architect will work on construction drawings...she said that takes up to four weeks. I'm hoping it doesn't take that long....I'm so ready to dig a hole! |
- Posted by neroselover (My Page) on Mon, Jun 9, 14 at 3:22
I think tapered columns would help change the look from farmhouse to craftsman. |
- Posted by Renovator8 (My Page) on Mon, Jun 9, 14 at 6:20
The dominant steep-roofed two-story narrow cross-gable element will prevent this house from successfully emulating the Craftsman Style no matter how many Craftsman features are added. Two story Craftsman cross-gables typically have a lower gabled front porch and in your case the front porch is added to the corner of the cross-gable and wraps around it ending in a small gabled portico. This might be considered a farmhouse form if the porch continued farther across the house. The result is more of a Folk Style house IMO. It's not imposible to make this house into a Craftsman Style but it would probably require moving the cross-gable back and centering a more dominant Craftsman-like one story front porch. A front or side gabled form might also be possible. It is clear that it was not the architect's intention to design a Craftsman house so I suspect there might have been a miscommunication in the early stages of the design process or the plan was developed too much before the style of the house was determined. |
michelle-I hear ya. So hard to wait wait wait but I think you will be glad that you re-worked things before forging ahead. One thing I might mention - just cuz we have been in 2 weeks and it's one thing that bothers ME is your bed against the master bath sink wall. Ours is not on it but next to it and I DO wake up when dh uses the sink in the middle of the night, it really cuts the silence. Maybe double drywall on that wall to buffer? |
- Posted by Michelle1973 (My Page) on Mon, Jun 9, 14 at 16:01
Thanks Autumn....I'll make a note to do some soundproofing on that wall. Renovator, thanks for commenting....I was hoping you would. We have since received a "more" craftsman like elevation. I understand this home doesn't fit the craftsman mold due to the two story set up, among other things. I'll post the new elevations soon (I'm on my phone right now). One thing we love about this look is the exposed rafters....but aren't those a great deal more expensive? Since we are already 500 sq ft over our target size, we must be careful. If the exposed rafters don't meet budget, is there a way to mimic the look without making the house look tacky? |
- Posted by Michelle1973 (My Page) on Mon, Jun 9, 14 at 16:35
Here's the new elevation. It changed up a bit in the laundry room area. There will be a small, high window to the right of the main entrance as well. So, what do you think? Does this new elevation look less farmhouse, more craftsman? |
- Posted by Renovator8 (My Page) on Mon, Jun 9, 14 at 19:36
The shed dormer should be pulled at least a foot away from the front facing gable so water can drain. In a cold climate it should be pulled away at least 2 feet. It's a much better design but it is still not a Craftsman house. The steep roofs, boxed cornices and pent roofed pediments are Victorian which is not a bad thing. You should allow the house to be what it wants to be instead of trying to disguise it as a style that is foreign to it. I see a great opportunity to make it into a Shingle Style house which I consider to be far more elegant and easy to adapt to modern life styles. It's almost there; the long continuous rake being a hallmark of the style. Add some more shingles that wrap around the corners (no corner boards), place the porch posts farther apart and make them tapered round or square columns (a column has a base and a capital) with entasis (convex side curve) and delete the big rake overhangs and brackets. Pair the windows with enough space between them to look traditional and use mullions only in the top sash. |
- Posted by Michelle1973 (My Page) on Mon, Jun 9, 14 at 20:23
Thank you, Renovator....I agree about the shingle style, and thanks for the heads up on the shed/gable dormers. I will ask architect. |
- Posted by Renovator8 (My Page) on Mon, Jun 9, 14 at 21:30
This Shingle Style house hangs on my wall to remind me that great houses can come from seemingly simple ideas. |
- Posted by Renovator8 (My Page) on Mon, Jun 9, 14 at 22:00
- Posted by Michelle1973 (My Page) on Mon, Jun 9, 14 at 22:47
Renovator.....I'm liking it! Thanks.....will definitely share with architect. :) |
- Posted by missingtheobvious (My Page) on Tue, Jun 10, 14 at 1:26
I'm worried about the width of the dining room. With 3 seats on the two sides of the dining room table, and those sides boxed in by the divider between living room and dining room on one side, and the kitchen island on the other side, there just isn't enough room. From the experts on GW's Kitchen and Bath forum: Walkways....In a seating area, 36" of clearance from counter/table edge to wall/obstruction if no traffic passes behind seated diners. 65" of total clearance when this includes a walkway (i.e., traffic). [From the NKBA Kitchen Planning Guidelines With Access Standards] It also looks like the corridor along the sink cabinets is too tight: both the area around the door between the kitchen and desk room, and also between those cabinets and the island. |
- Posted by Renovator8 (My Page) on Tue, Jun 10, 14 at 8:56
I have no idea if such a design would be appropriate for your location; it's just an idea for simplifying and unifying the character of the exterior. Shiplap boards on a ceiling would require face nailing. Tongue & groove boards would be better. |
- Posted by Michelle1973 (My Page) on Tue, Jun 10, 14 at 9:41
missingtheobvious, I very much appreciate that you took the time to look at the plans. Your post spurred me to measure my current dining room to see if I need to add more on to the plan. Our current dining room is 11 feet wide, and there are bar stools included in the width. Plus, our current table is 47" wide, and the table I plan on ordering from Restoration Hardware is 42" wide. The dining room on the plans is 11' 5" inches, with about 6 inches being eaten up by the wall divider. But, I gain back 5" with the narrower table. My current dining room is PLENTY big for our needs. So, I feel comfortable moving forward with the size in the dining room. But thank you! |
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- Added: 02 February, 2011
- Idol: Maria Ozawa
- Duration: 112 minutes 11 sec ( 4 scenes )
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Sept 19, 2007
If there's one thing the Guilty Gear games have always done well, it's get us pumped up to kick some faces in. And with its blasting rock music, brilliantly colored fighting arenas, and frantic one-on-one 2D fighting action Guilty Gear XX Accent Core doesn't stray from tradition. In fact, it's really not much of a change at all - one might call it a stripped down, re-mastered XX, which is a bit disappointing when we're used to every iteration of the series pushing it to new areas. That aside, the changes that have been made, while minimal, do make it even better, and Accent Core is absolutely a must-have for any fan of 2D fighters.
So what's different? Two new characters, Order Sol and A.B.A., have been added to the roster, and both are as unique as any other character in the game - in other words, they're completely insane. A.B.A., for instance, is a bandaged, bleeding girl - actually a manufactured human - who carries a seven foot-tall key with a smiley face on it. Both have appeared in previous games, but Sol's wasn't released in the US and A.B.A.'s was a side-scrolling beat 'em-up, so this is the first time both are in a traditional, US-released fighting game. Justice and Kliff however, are not in this version, so the roster stands at a still healthy 23 characters, not counting the alternate "EX" versions of each one.


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How do you keep children safe online?
Don't miss the highlights from our Twitter chat with online behaviour expert Ellen Ferguson in support of Safer Internet Day
Your help is delivering free school meals
Our Fair and Square campaign has helped bring free school meals to 200,000 more children in poverty
Steps in the right direction for trafficked children
We welcome government plans to trial independent advocates and new guidance for unaccompanied and trafficked children - but these young people need more
Become a DO-er today and enjoy whatever you DO
Our vibrant, new DO appeal is all about having fun doing what you enjoy for a cause that is doing great things for disadvantaged children - join in today
Cold Homes Week: Tackling the scourge of fuel poverty
New statistics reveal 2.2 million children in England in fuel poverty, an increase of 26% in the last year
'Yes, I'll climb Mount Kilimanjaro on my honeymoon'
Nigel Varndell, our Director of Church Partnerships, will spend his honeymoon climbing Kilimanjaro and raising funds for our work - please support his efforts
Become a DO-er today and enjoy whatever you DO
Our vibrant, new DO appeal is all about having fun doing what you enjoy for a cause that is doing great things for disadvantaged children - join in today
Extend free school meals to all families on universal credit
New government data reveals a rise of 250,000 children in poverty in working households
Boys don't cry? Young men can be victims of sexual exploitation, too
Our project in Lancashire recently hosted an event focusing on the under-addressed problem of sexually exploited boys and young men
Ten young people organise Bake and Brew event, raise money for our work
Ten young people hosted a Bake and Brew event, raising funds to support our work with vulnerable children across the country.
These beautiful photographs reflect young people's heritage, new home
After years of working with Roma and migrant children, artist Marta Kotlarska explains the importance of a new exhibition of young people's photos


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Sunday, January 10
Staples Center
Attendance: 18,997
Los Angeles, CA (Sports Network) - Shannon Brown scored 15 of his season-high 19 points in the second half, and the Los Angeles Lakers overcame an awful shooting night by superstar Kobe Bryant to beat Milwaukee, 95-77, at Staples Center.
Bryant, still playing with an avulsion fracture of his right index finger, went 4-of-21 from the field and finished with 12 points. Andrew Bynum had 17 points and 18 a career-best rebounds, while Lamar Odom pulled down 17 boards to go with nine assists and five points.
"We came out with a defensive mind and it worked out well for us tonight," Bynum said.
Jordan Farmar scored 17 -- 15 in the second half -- and Derek Fisher tallied 11 for the Lakers, who snapped a two-game skid and beat the Bucks for a fifth straight time. That includes a dramatic 107-106 overtime win in Milwaukee on December 16 when Bryant hit the winning shot at the buzzer.
"Sometimes these guys watch too much football for the way they played in the first half," Lakers coach Phil Jackson said. "We finished the game on a good note."
Bucks guard Michael Redd was helped to the locker room late in the first quarter with a sore left knee he suffered while driving to the hoop. He'll be examined Monday.
Hakim Warrick scored 14 for the Bucks, who had a three-game winning streak broken. This was the start of a six-game road trip for Milwaukee.
"We didn't have enough guys that played well," Bucks coach Scott Skiles said. "Our defense played well, but we couldn't get anything going offensively."
Milwaukee shot a horrific 4-of-21 in the opening quarter and scored just eight points, trailing by 16 after 12 minutes. The struggle by the Bucks allowed the Lakers to bolt to a 22-4 lead, a spurt Bryant finished with a pair of foul shots with 2 1/2 minutes left in the period.
The Lakers nearly gave that back in the second though, going 5-of-19. They still came away with a 39-28 lead at halftime. Milwaukee was within five early in the second before falling behind by 14 later in the quarter.
It was a much different story in the second half for the Bucks, as their defense broke down in allowing the Lakers to pull away. Brown ended with third quarter with a half-court shot for a 65-46 cushion, and the lead reached as high as 26 in the fourth.
Ron Garretson
Eric Dalen
Pat Fraher


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- Shopping Bag ( 0 items )
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Includes learning activites and definitions to help your child excel at language arts.
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Includes learning activites and definitions to help your child excel at language arts.
Once upon a time, there were three pigs: a big pig named Pig, a bigger pig name Pigger, and the biggest of the three name Piggest. They all lived in the castle of their father, the king.
One day their father called them in. "Pig," he said, "when you were born you were a little pig. And Pigger, you were an even littler pig. And Piggest, you were the littlest of my dear, sweet, dirty babies. But now you are great big pigs. And this castle isn't big enough for the four of us. It is time for you to go out and build homes of your own."
"Oh, yay!" the pigs said. "Homes of our own!" And off went Pig, Pigger, and Piggest.
As my be obvious to all this is a tale that springs from the Three Little Pigs theme. Certainly there are hundreds of these tales, however, if one were to read this story one would be delighted. It does carry the theme of the three little pigs and yet treads a new ground that gives these pigs their own porcine identity. This is somewhat established by the use of inflected endings(-er,-est). The absence of "The Wolf" as an antagonist is a refreshing change from this adaption of a classic tale. Using instead a trio of sister witches to make demands upon our heroes. The pigs overcome the difficulties and come upon an ending that I think most will enjoy, as it is not what some may expect.
The use of inflected endings is displayed nicely in the narrative and in the equally well crafted illustrations. This book will be a treasured addition to my classroom library, as it is well written and illustrated and also provides a nice example of the inflected endings -er and -est (and, yes, that is a selling point for me). I highly recommend this book to teachers, parents and fans of the Three Little Pigs genre.
Posted February 10, 2012
No text was provided for this review.


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Technical Data |
PARP Cleavage Site, p85, Asp214/Gly215 (Poly ADP-Ribose Polymerase) |
Description: Poly (ADP-ribose) polymerase (PARP) is zinc-dependent DNA binding protein that recognizes DNA strand breaks and is presumed to play a role in DNA repair (1). As a marker for apoptosis, PARP is cleaved in vitro by many caspases, and in vivo by Caspase-3 (2,3). Existing as a 116kD nuclear protein, PARP is cleaved between amino acids Asp214 and Gly215 to yield two fragments of 29kD and 85kD (2,4). Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunocytochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50 Western Blot: 1:1,000 Immunocytochemistry: 1:50 Immunoprecipitation: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam. |


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Stormborn Shawl
This pattern was used for the Game of Thrones MKAL 2014! Details regarding the MKAL are below, however if you purchase the pattern today, you will receive the option to download the pattern in it's full form instead of in clues.
Here are the details for this year's Game of Thrones Mystery KAL:
-The KAL pattern will be released in 6 clues on the following dates:
May 4th - Clue 1
May 11th - Clue 2
May 18th - Clue 3
May 25th - Clue 4
June 1st - Clue 5
June 8th - Clue 6
-This year we will be knitting a lace shawl inspired by Daenerys Targaryen! The mystery is in the design…
-The recommended yarn is 2 skeins of Lorna's Laces Shepherd Sock and we are using the May '14 Limited Edition color designed especially for this KAL - "Fire and Blood" which will be released on Friday, April 25th and only available at Jimmy Beans Wool. Lorna's Laces Solemate is also an appropriate substitute, and as usual, you are welcome to use ANY fingering weight yarn of your choosing. You are never required to buy yarn from Jimmy Beans Wool to participate in one of our KALs. Anyone is welcome!
-The pattern difficulty level is considered Intermediate. The stitches are basic enough (a list of abbreviations is available immediately when you download the pattern in case you need to brush up on any skills), but there is some interesting shaping that may challenge you a bit (in a good way of course.)
-The pattern will include both written instructions AND charts (by popular demand!)
-The KAL will be hosted entirely on Ravelry this year, so the pattern will also only be available on Ravelry.
-Each Sunday during the KAL, you'll receive a message on Ravelry that the pattern has been updated. You can download and print each clue individually, week by week.
-After the KAL is complete, everyone who purchased the pattern will receive a final version of the pattern in it's fully formatted and completed form.
-As usual, we'll have threads for each clue in the Jimmy Beans Wool Group here on Ravelry, so come on over and join in the conversation, ask questions, get help with the pattern, etc.!!!
If you've participated in past KAL's with JBW and myself, feel free to check out the JBW Blog explaining some of the improvements/changes we've made to our KAL format. We think you are going to love it!


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- Vancouver Canucks Top Prospects
- Written by Brendan Ross
Dane Fox, C |
Shoots: L |
Height: 6-0 |
Weight: 185 |
Born: 1993-10-13 |
Hometown: Thamesville, ON, CAN |
Drafted: Undrafted, signed Vancouver Canucks Jan. 2014 |
May 2014 - After leading the OHL in goals, Dane Fox was named to the OHL's 1st All-Star Team joining Scott Laughton, teammate Connor Brown, Aaron Ekblad, Slater Koekkoek and Alex Nedeljkovic. Fox's junior hockey comes to a close so he will be competing for a roster spot with the Canucks in 2014-15 but it's more likely the skilled agitating winger heads to the AHL. Brendan Ross
January 2014 - The top scorer in the OHL by a wide margin (42 goals in 39 games) was recently signed by the Vancouver Canucks. He admits to making some personal mistakes in the past which could partially explain why he wasn't drafted two years running (ranked 48th last year by NHL central scouting). After hovering around a point per game pace for a few years, Fox is up around two points per game with 70 points as an overager. Some of that undoubtable comes from his linemates, notably Connor McDavid, but that is not all he brings. In an interview with Dean Youngblood, Fox said that he models his game after Steve Ott and Dave Bolland. His coach lauds him for his complete game and grittiness, saying that he is defensively responsible and doesn't cheat offensively; he projects Fox as a third liner with powerplay time in the NHL. Austin Wallace
While he is currently scoring a torrid pace, even for an overager, it is likely to be his grit that will secure him a spot at the NHL level. He models himself after Dave Bolland and Dave Bolland the third liner is a good fantasy comparable.
Dane Fox highlights:
Fantasy Prospects Report Notes (Any FPR's released in the last 18 months will not be listed here):
Buy the latest Fantasy Prospects Report here.
Dane Fox statistics courtesy of Elite Prospects


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Roberta Howard, CEO (928) 442-9205 ext. 3 Fax: (602) 535-3230 firstname.lastname@example.com
I would like to welcome you to our website and thank you for your interest in NAZCARE. We are glad you stopped by and hope this website will answer some of the questions you or others may have about our organization's mission, vision, values and services. Please feel free to contact us at any time! If you are looking for community wellness centers, recovery services, supportive housing, career training, supportive employment; we would love the opportunity to speak with you. NAZCARE is a quality recovery organization. We are a Peer-Operated agency. Most of our employees are peers and family members. We seek to enhance wellness, promote recovery, reduce stigma and reach out to consumers throughout the United States. Join us in our journey of recovery and better whole health and reducing stigma in your community.
NAZCARE, Inc. has spent a good deal of time working on a peer stabilization program which will lead to change in the crisis system in Arizona. NAZCARE drew upon Roberta L. Howard's experience working in-patient facilities and peer support recovery services to design this model that is implemented in phases. The first phase is the implementation of peer support groups within psychiatric facilities to establish a connection to peer and natural supports for an in-patient client once they leave the facility. The peer staff from NAZCARE also helps to identify needs of a client at and after discharge and convey this to the social work staff in order to better meet the needs of a client and prevent and reduce recidivism rates. Phase to is the implementation of services at time of discharge and after discharge along with a huge re-engagement piece. NAZCARE peer staff follows up with phone calls and home visits to check on the safety and wellness of a client and any concerns in order to address issues in a timely manner and eliminate barriers that may lead to crisis and relapse. NAZCARE is located throughout rural Arizona and thus us able to handle out-of-area placements with the same support and services through the model. If you have any questions, please contact,
Roberta l. Howard at (928) 830-6116 firstname.lastname@example.com
NAZCAREprovides the needed training and certification to become a Peer Support or Recovery Support Specialist. Our certificate is portable recognized by states through the US, Internationally and by the Veterans Affairs Administration. Trainings can be available for D/HH by a Deaf trainer who is fluent in ASL. NAZCARE's program is an evidence-based program...read more(Click Here)
Peer services inside a clinical setting are to integrate peers into clinical setting in order to change the cultural of an organization to be more recovery oriented from recovery language to awareness to recovery needs through peer services.
Peer services by a peer run organization are to integrate peers into the community through a community-based peer services from socialization, citizenship, adult life skills, community integration and community services to reduce and live stigma free as an integrated member of the community. Peer runs allow a person to self-direct one's recovery services and to have voice and choice in the recovery activities that occur at a peer run.
Peer services work in coordination of care along the continuum of care. A peer should not have one or the other but both.
Clinics and peer runs can bill for services on the same day – just NOT at the same time. Peer runs are block purchase and improve the CAP rate! Clinics may copy what we do in a clinical setting but the approach, methods and setting are NOT the same.


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Results tagged "Pakistan"
Would you like to limit the tag results display to a specific section?
If you do, then pick any of the sections below:
Or simply go to the aggregated tag results from:
Militants killed three people in a bombing at a Sufi shrine in Peshawar and two more in a bombing at a mosque in Quetta. The Taliban killed a soldier in an attack in South Waziristan.
Pakistan judge orders arrest of PM nominee Shahabuddin
Indonesia court to deliver verdict on Bali bombmaker
Pakistan - PM's disqualification delays signing of NATO supply deal
Pakistani Taliban's anti-US rant: 'Peace treaty to stay intact despite polio drive ban'
Dr Aafia still alive: US prison spokesperson
Pakistan detains al Qaeda operative tied to multiple plots
An al Qaeda operative named Naamen Meziche has been reportedly detained in Pakistan. Meziche had extensive ties to the 9/11 plotters and was part of a 2010 plot to launch Mumbai-style attacks in Europe. That plot also had significant links to al Qaeda's Iran-based network.Pakistan nabs French man with reported 9/11 links
Questions on Women's Rights and Ethnic Strife in Afghanistan
Ghazala Javed: A nightingale plunged into silence
Pakistan Supreme Court Dismisses Prime Minister
Popular Pakistani singer Ghazala Javed killed
Violence spikes across southern Afghanistan
Army won't leave South Waziristan: Kayani
Human traffickers in Pakistan stealing British sponsors' data
ISAF kills IMU, al Qaeda-linked Taliban commanders in airstrikes
The Taliban commanders killed in Nangarhar "facilitated the movement of foreign fighters across the border from Pakistan into Afghanistan." The Islamic Movement of Uzbekistan commander was involved in the kidnapping of four aid workers in Badakhshan.Pakistan's hardline groups ask gov't to shoot down US drones
Pakistan - In return for 'tactical' support, PPP won't field candidate against Fazl in elections
Pakistan - Tribesmen mourn Landikotal blast


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The Sample List is a listing of salesmen's samples, store display models, factory blemished, refurbished, trade-ins, products with damaged packaging, discontinued products and close-outs. Below are a few examples of goods that are currently on The SampleList.com web site.
See All Sample List Merchandise
Does any body know he formular for the height difference between back and front scope blocks? Thanks for your answer, Hank45
Northern British Columbia daveco2015-01-30 21:07:02
I have season tickets to college basketball. We are about half way up. I can see the game well enough but at times I would like to have some binocu...
So I replaced my Luepy GR 50mm spotter with a Pentax EDII 65mm a month ago. First off, great decision. Looking through the Leupy at 30X was no...
I had posted this on a firearms forum and someone said to join here and ask. I never knew this forum existed. So, firstly, hello.I was just wonderi...
All content copyright 2012 SWFA Inc.


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I'm looking for a language school near Lake Atitlan where I can learn a Mayan language, preferably tzotzil. Any help you can provide in helping me find this would be much appreciated!
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Amla honey shot, the sour indian gooseberry and honey – this is definitely a match made in heaven! star anise contributes a faint but appreciable aroma and flavour to the drink. Remember not to add too much star anise lest it steals the show without letting the other ingredients to shine. Glass used: shot glass
Preparation Time: 10 mins Makes 4 glasses Show me for glasses
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unusual combination! i drink fresh amla juice every morning...i must try it honey and star anise..is it ok if i do not use amla crush i want to avoid extra sugar
Bubbly Recipes with Baby Corn Missed out on our mailers?Our mailers are now online! View Mailer Archive


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A newer version of DRoster is available.
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DRoster's rostering capabilities respond to the needs of my organization. Its robust features (correlating staff with duties and user-defined reports) give flexibility in handling my hectic employee scheduling demands. The interface is user-friendly and intuitive. So far, it excells!


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This photo was shot on film. Taken by warning with a Lomo LC-A+ (available in our Online Shop) loaded with Kodak E100VS film in Madrid, Spain. These tags describe this photo: party, fiesta, premier, friends, amigos, presentación, movies, 35mm, cine, alfombra roja, red carpet, glamour, and lomokino. Date: 2011-11-03. Time: Night. This photo can be found in the album Lomokino Glamour.Please login to get more out of this site
You are currently not logged in, do so now to add comments, like articles as well as photos, submit to competitions, translate articles and gain access to unlimited photo upload! If you are not registered yet, go here to find out more about Lomography and join now! If you just want a limited account for now you can use Twitter or Facebook. We would love to have you as a member here!
56 people like this photo
Liking photos helps us to present the best ones to you and others. 56 people like this photo. 56 people like this photo: franan, chourique, isabel_mebarak, javihacefotos, weidong, meryl, lauralaula, clickiemcpete, littlekoala, atria007, adzfar, dakadev_pui, jandra, racarrete, sprofishgel, oscarrastaman, soleado, disdis, aprilrich427, icomewhenieatcaponata, moodification, albeelee, laviejasirena, realrampage, mapix, lola_juanlu, lilithmoon, sye, jeabzz, robter, mikahsupageek, adi_totp, suizidekid, hankerkizia, susielomovitz, emkei, johnnyfun, iskandar, lawypop, jennson, nicolas_noir, alisanri, neja, pepper-b, valennano, mafiosa, kitija, russheath, ena, escudero, wuxiong, mephisto19, kylethefrench, lisa-lisa, kiteflyin, and cyan-shine.
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@horaciov, el más elegante!!, sí que iba guapo!!
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When insomnia and technological convenience collide, a lifetime of binge reading reaches its full potential.
When insomnia and technological convenience collide, a lifetime of binge reading reaches its full potential.
A visit to the granddaddy of Japan's capsule hotels—with cot-sized individual spaces and shared amenities—and a lesson in different methods of getting along.
Just before and right after President Obama's State of the Union address, an editor telephones complete strangers around the country, to find out what's really going on.
Ignore the critics: Christopher Nolan's Interstellar is not only a serious, complex comment on space policy, it's a heartbreaking, philosophical look at the value of time.
How a book, booze, and a guilty hangover brought an admittedly non-athletic man to the starting line, and what happened next.
Even a fake history of blogging—going back to the Old Internet, when HTML templates were so raw—offers insight.
Micro-living is no longer just for the very poor and the very bohemian. But how much space do we really deserve?
Everything you need to know—in cartoon form—about debt-ceiling fiascos, from McKinley's war with Spain to Obama getting punk'd.
Another bag goes in, more waste goes in the landfill. A startling look at America's capacity for making garbage.
When insomnia and technological convenience collide, a lifetime of binge reading reaches its full potential.
I just spent the past four months reading all eight books in the Outlander series—and a five-book spinoff series—back to back. It wasn't because they were especially transcendent or because I'd become a fan of the Starz show. It was just because they were fun, and because I wanted to see how Jamie and Claire turned out.
And why not? Life is short, and my nights are long—two excellent reasons, as far as I'm concerned, not to endure cliffhangers or loose ends unnecessarily.
It started with A Game of Thrones, the book that launched a thousand HBO binges. It wasn't the kind of thing I usually read, but I figured it would be good in its own way. I had thoroughly enjoyed reading the Da Vinci Code on my last vacation—but I expected I'd finish it and move right along to the new Ondaatje or Mantel or Murakami. But after I finished the first book, I wanted to keep reading the series, and I wanted to read it all right away.... Continue Reading


text: Lucky me! I was found by some nice people and brought here so that I can be adopted into a loving home. I am very deserving of a family who will give me all the attention I need. It has been recommended that I go to a home with no small children. People here will tell you I can be vocal and I enjoy pets...especially on my head. Looking forward to meeting you soon. I am at the Dumb Friends League, 2080 S. Quebec Street, Denver and my ID# is 0695457. To see my other furry friends available for adoption, please visit ddfl.org.


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A missing baby has been found alive in Houston — thanks to a jogger.
The jogger stumbled upon the 8-month old baby girl on the side of the road yesterday – crying and strapped inside her car seat. Police say the baby had been kidnapped just hours earlier.
An 8 month old baby girl, alone, abandoned in the woods, crying out for help. Those cries heard by this woman, Hong Nguyen, who just happened to be visiting from Vietnam, and just happened to be on her first jog of the trip on this very day.
"I just come there…. see and take pictures…one, two…and stay there until the policeman come to keep the baby safe."
The baby abandoned after a carjacking in a Texas gas station. The mother, seen here in tears moments after the abduction. Police say she'd left the car running, with her baby, Genesis Haley, in the back while she made a quick run inside a stor, within seconds, the car and the baby were both gone.
"She went in it look liked a matter of a few moments."
The car was found abandoned, but for hours, the search for Genesis came up empty, until those cries were heard.
"We were very worried. But we're very glad that that jogger just happened to turn around to see her in her car seat."
And as heartbreaking as this photo is, this photo – of officer Albert pizana swaddling baby Genesis in his uniform – is equally uplifting.
"Whenever we can recover a baby that's alive it's very reassuring in our job."
Now the manhunt is on for the man who left her in the woods. Police have released this sketch.
"She describes him as a young black make with a slight slant in his hairdo and he has a small white or blondish patch on one side. So it's a pretty distinct picture of him."
Police say apart from being hungry and suffering what appeared to be several ant bites — Genesis was in good health when she was found.


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Some of these memories, oddly enough, are ascribed to other Tuskegee students of the era, as if Murray can creep out of his solipsistic shell only by degrees. And some have a collegiate friskiness to them, which seems only appropriate. Here, for example, Murray runs down the faculty roster, culminating in that agricultural wizard George Washington Carver, who was then so old that Henry Ford would soon pay to have an elevator installed in Carver's Tuskegee lodgings:
They all will remember W. Henri Payne with his brownskin Frenchman's moustache whether they took French or not that year. They will remember Alphonse Henningburg and his beautiful wife. Nor will anybody have forgotten that the only way to repeat anything Dr. Carver said was to imitate him in as high a pitch as possible (adding precisely enunciated dirty words which would have horrified him: "They ask me: 'Dr. Carver what makes rubber stretch?' and I say to them quite frankly I don't cop what the fuck makes that shit act up like that, I don't dig no rubber-stretching shit. I dig peanuts, I dig potatoes.")
It's instructive to compare Murray's Tuskegee interlude with the one V. S. Naipaul included almost 20 years later in A Turn in the South—after Murray himself prepped him for the visit! Naipaul's account is careful and cumulative. He gets the facts, elicits testimony from a couple of locals, and as he explores the broiling interior of Tuskegee's Dorothy Hall, notes that the "colors in the hot paneled club upstairs were like the colors of a gentlemen's club." The irony is unmistakable, but also quiet: a murmur. Whereas Murray is sweeping, breathless, atmospheric. He wants the feeling of the place, and the memories of it, and he wants to surprise himself in the act of remembering.
In Mobile, at last, he is really back home. There the Scott Paper Towel factory has gobbled up the landscape of his youth like a "storybook dragon disguised as a wide-sprawling, foul-smelling, smoke-chugging factory, a not really ugly mechanical monster now squatting along old Blackshear Mill Road." There Murray wanders the streets and connects with half-remembered acquaintances. And there, for the first time in the book, other voices climb confidently into the driver's seat.
In fact, the chapter is jammed with lengthy, back-porch soliloquies. Murray seldom identifies who is talking. And given the preoccupations of the speakers, which happen to be his preoccupations, it's pretty clear that he orchestrated and intensified what they had to say (much as he would later channel Count Basie in the bandleader's autobiography, Good Morning Blues). In any case, the results are frequently hilarious. One such speaker gives the back of his hand to the Black Power dream of African repatriation. The Africans, he says, will
take one look at them goddam jive-time Zulu haircuts and them forty-dollar hand-made shoes and they going to lock your American ass up in one of them same old slave-trading jails they put our ancestors in, and they going to have you writing letters back over here to this same old dog-ass white man in the United States of America asking for money. Hey, wait. Hey, listen to this. Ain't going to let them get no further than the goddam waterfront. They go lock them up with a goddam Sears, Roebuck catalogue. I'm talking about right on the dock, man, and have them making out order blanks to Congress for Cocolas and transistors, and comic books, cowboy boots and white side walls and helicopters and all that stuff.
This is identity politics as black comedy, with some incidental buckshot fired at American-style consumerism. It is also a sly bit of self-mockery, since Murray himself was an avid consumer of fine clothes, fine art, audio equipment, and probably the occasional transistor. And as a boyhood admirer of Tom Mix, he must have longed for the cowboy boots as well. Maybe he should have shared the microphone more often.
Murray's chronicle of his journey never appeared in Harper's. Perhaps Willie Morris found it too weird and wandering for his taste. It was one thing, after all, to devote an entire issue of the magazine to the heavy-breathing theatrics of Norman Mailer's "The Prisoner of Sex," quite another to publish Murray's unclassifiable (and occasionally unreadable) circuit of the South. More to the point, Morris himself was forced out in 1971. The owners argued that revenue was down and blamed the editor's penchant for long, liberal, supposedly ad-repelling articles. In that climate, it's no wonder that the raw materials for South to a Very Old Place got spiked.


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January 31, 1996
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