text:
A short article in the New Yorker on my favorite topic – business models for antibiotic use and innovation.
Category Archives: Research Funding
The Revival of Phage Therapy to Fight Antimicrobial Resistance (AMR) – Part III: What about patent protection and alternative incentives?
In Part II of this blog on legal issues relating to the revival of phage therapy I discussed the US Supreme Court's decisions in Myriad and Prometheus, which might present major obstacles to the patentability of phage-related technology (a more detailed analysis of the Myriad and Prometheus decisions is available here).
Yet, all is not lost. As indicated in Part II, Myriad does not directly affect the patentability of synthetically modified biological compounds and Prometheus would still allow patents on inventive applications of natural processes and correlations that add new features to "natural laws". Thus there still seems to be considerable leeway for patenting within the area of page therapy.
One example, mentioned in a recent Nature article, could be the skillful selection and precise combination of different phages in order to attack one specific type of bacteria. Such selections, however, would face a tough battle to overcome the "additional features that add significantly more" and "not identical" thresholds set by Prometheus and Myriad. Another example with even better prospects for patentability relates to genetically modified phages that are – due to human intervention – enabled to target only specific bacteria. This technology was recently presented by MIT researchers at the 2014 American Society for Microbiology Meeting. The researchers led by Timothy Lu had genetically engineered phages that use a DNA-editing system called CRISPR to target and kill only antibiotic-resistant bacteria while leaving other susceptible cells untouched. The significant engineering and alteration of natural products and processes involved in such inventions would most likely meet both the Myriad and Prometheus standards.
Yet, while the USPTO has recently issued new patent eligibility guidance and the CAFC has begun to directly apply Prometheus and Myriad to reject patent claims in biotech cases (e.g. In re Roslin), many questions remain unsolved. In particular, it is still not sufficiently clear exactly how much modification is required to render a molecule or method sufficiently distinct from naturally occurring product and processes. And even if the patent-eligibility threshold could be met in extraordinarily circumstances, the claimed invention would still have to fulfil other patentability requirements such as novelty, non-obviousness and the written description-requirements. The threshold for these requirements, however, have been heightened in recent years (see e.g. KSR v. Teleflex (2007) , Nautilus (2014) etc.). Considering that phage therapy is almost a century old with a substantial common general knowledge and a state of the art employing routine methods, these crucial requirements might still prevent the patentability of many useful applications.
The Revival of Phage Therapy to Fight Antimicrobial Resistance – Part II: What about patent protection and alternative incentives?
Three days ago I commented on a couple of legal issues raised in the recent Nature report "Phage therapy gets revitalized" by Sara Reardon. One challenge concerns the reluctance of pharma companies to broadly invest in the development of phage therapies. As pointed out in the report, this does of course very much (but not only) relate to the question of patentability. Various aspects might present obstacles to the patentability of technology relating to phage therapy. To not complicate the discussion and considering recent developments I decided to focus on some of aspects under US patent law.
Like in Europe, the first door to patentability that phage-related technology would need to pass concerns patent eligibility. In the last years the US Supreme Court has rendered an astonishing number of fundamental patent-decisions, including not less than four (!) landmark judgments on patent eligibility, i.e. Bilski v. Kappos (2010), Mayo v. Prometheus (2012) , AMP v. Myriad (2013) and Alice v. CLS (2014). Most relevant in this context are the decisions in Prometheus and Myriad.
My Slate Article on the Importance of Replicating Science
I have a long article in Slate (with Chris Chabris) on the importance of replicating science. We use a recent (and especially bitter) dispute over the failure to replicate a social psychology experiment as an occasion for discussing several things of much broader import, including:
- The facts that replication, despite being a cornerstone of the scientific method, is rarely practiced (and even less frequently published) not only in psychology but across science, and that when such studies are conducted, they frequently fail to replicate the original findings (let this be a warning to those of you who, like me, cite empirical literature in your scholarship);
- Why replications are so rarely conducted and published, relative to their importance (tl;dr: it's the incentives, stupid);
- Why it's critical that this aspect of the academic research culture change (because academic science doesn't only affect academic scientists; the rest of us have a stake in science, too, including those who fund it, those who help researchers produce it (i.e., human subjects), those who consume and build on it (other scholars and policy-makers), and all of us who are subject to myriad laws and policies informed by it); and
- Some better and worse ways of facilitating that cultural change (among other things, we disagree with Daniel Kahneman's most recent proposal for conducting replications).
How an IRB Could Have Legitimately Approved the Facebook Experiment—and Why that May Be a Good Thing
By now, most of you have probably heard—perhaps via your Facebook feed itself—that for one week in January of 2012, Facebook altered the algorithms it uses to determine which status updates appeared in the News Feed of 689,003 randomly-selected users (about 1 of every 2500 Facebook users). The results of this study—conducted by Adam Kramer of Facebook, Jamie Guillory of the University of California, San Francisco, and Jeffrey Hancock of Cornell—were just published in the Proceedings of the National Academy of Sciences (PNAS).
Although some have defended the study, most have criticized it as unethical, primarily because the closest that these 689,003 users came to giving voluntary, informed consent to participate was when they—and the rest of us—created a Facebook account and thereby agreed to Facebook's Data Use Policy, which in its current iteration warns users that Facebook "may use the information we receive about you . . . for internal operations, including troubleshooting, data analysis, testing, research and service improvement."
Some of the discussion has reflected quite a bit of misunderstanding about the applicability of federal research regulations and IRB review to various kinds of actors, about when informed consent is and isn't required under those regulations, and about what the study itself entailed. In this post, after going over the details of the study, I explain (more or less in order):
- How the federal regulations define "human subjects research" (HSR)
- Why HSR conducted and funded solely by an entity like Facebook is not subject to the federal regulations
- Why HSR conducted by academics at some institutions (like Cornell and UCSF) may be subject to IRB review, even when that research is not federally funded
- Why involvement in the Facebook study by two academics nevertheless probably did not trigger Cornell's and UCSF's requirements of IRB review
- Why an IRB—had one reviewed the study—might plausibly have approved the study with reduced (though not waived) informed consent requirements
- And why we should think twice before holding academics to a higher standard than corporations
"That's a Lot of Marijuana"
Nadia N. Sawicki
Earlier this month, the Drug Enforcement Administration issued notice that it would be increasing the 2014 production quota for marijuana from 21 kilograms to 650 kilograms – an almost 3000% increase. In the words of DEA spokeswoman Barbara Carreno, "That's a lot of marijuana." This step, according to the National Institute on Drug Abuse (NIDA), was a necessary response to a dramatic increase in current and proposed marijuana research. Continue reading
A More Transparent System for Clinical Trials Data in Europe – Mind the Gaps!
Following the approval of the European Parliament (EP) earlier last month, the Council of the European Union (the Council) adopted on 14 April 2014 a "Regulation on clinical trials on medicinal products for human use" repealing Directive 2001/20/EC. As described in a press-release, the new law:
"aims to remedy the shortcomings of the existing Clinical Trials Directive by setting up a uniform framework for the authorization of clinical trials by all the member states concerned with a given single assessment outcome. Simplified reporting procedures, and the possibility for the Commission to do checks, are among the law's key innovations."
Moreover, and very importantly, the Regulation seeks to improve transparency by requiring pharmaceutical companies and academic researchers to publish the results of all their European clinical trials in a publicly-accessible EU database. In contrast to earlier stipulations which only obliged sponsor to publish the end-results of their clinical trials, the new law requires full clinical study reports to be published after a decision on – or withdrawal of – marketing authorization applications. Sponsors who do not comply with these requirements will face fines.
These groundbreaking changes will enter into force 20 days after publication in the Official Journal of the EU. However, it will first apply six months after a new EU portal for the submission of data on clinical trials and the above mentioned EU database have become fully functional. Since this is expected to take at least two years, the Regulation will apply in 2016 at the earliest (with an opt-out choice available until 2018).
New regulatory pathways and incentives for sustainable antibiotics: Recent European & US Initiatives
Please find attached a ppt presentation on "New regulatory pathways and incentives for sustainable antibiotics: Recent European & US Initiatives" given on March 7, 2014 at the Broad Institute of MIT and Harvard. The presentation was followed by a discussion moderated by US patent attorney Melissa Hunter-Ensor, Partner at Saul Ewing, Boston.
I started out by emphasizing increasing problems of antimicrobial resistance (AMR) on a global level, providing new statistics and facts. This was followed by a discussion of main reasons for these alarming developments, such as inappropriate use in agriculture and medicine, insufficient precautions, lack of education, climate change, travel behavior, insufficient collaboration and funding of R&D, scientific complexities, and the problem that incentives provided by the traditional innovation system model often fail in the case of antibiotics.
Next the presentation focused on a variety of solution models that could be discussed to fight AMR. These include both conservational and preventive approaches comprising use limitations, increased public awareness, and better hygiene, but also reactive push & pull strategies, such as increased investments, new collaborative models for R&D in antibiotics, prizes, "sui generis" IP-related incentives, regulatory responses and new pathways for approval.
Clinical Trials of Primary Care Drugs: Could Smaller Be Better?
By Kate Greenwood
Cross-Posted at Heath Reform Watch
Lately it seems that each passing day brings another article about the cost of orphan drugs. Earlier this week at FiercePharma, Tracy Staton reported that the United Kingdom's National Institute for Health and Clinical Excellence (NICE) has asked Alexion Pharmaceuticals to justify the price of its drug Soliris which is, per Staton, "the most expensive drug in the world" at around $569,000 a year. Specifically, NICE seeks "'clarification from the company on aspects of the manufacturing, research and development costs'" of the drug. According to Staton, this latest development in a review process characterized by "halting progress" is "a departure from NICE's usual calculations, which typically focus on quality-of-life years and the like."
Pushback by NICE and other payers notwithstanding, the orphan drug market is growing. As I blogged about here, in 2013 EvaluatePharma estimated that "the worldwide orphan drug market is set to grow to $127 [billion], a compound annual growth rate of +7.4% per year between 2012 and 2018[,]" which "is double that of the overall prescription drug market, excluding generics, which is set to grow at +3.7% per year." In a recent article in the New England Journal of Medicine, venture-capital investors Robert Kocher and Bryan Roberts note that "more than half of the 139 drugs approved by the FDA since 2009 are for orphan diseases" and suggest that there is a risk of "systematically underinvesting in other important areas of medicine."
Kocher and Roberts' explain that one reason that orphan drugs attract investment is that their development costs are low. The problem or potential problem of underinvestment in diseases like depression and diabetes could therefore be addressed, they contend, by bringing the cost of developing treatments for these common conditions in line with the cost of developing treatments for rare diseases. And, they argue, one promising approach to doing so is to reduce clinical trial costs by reducing the size of clinical trials. Continue reading
Kevin Outterson on the Search for New Antibiotics
Kevin Outterson appeared on NPR's "Here & Now" to discuss the growing problem of antibiotic resistance and possible ways to incentivize development of new antibiotics. From the interview:
On the misuse of antibiotics
"We should think of this as a global resource that needs to be conserved and taken care of. So antibiotics should never be used inappropriately. In the country right now, we have something on the order of 23 million people who are getting antibiotics for ear aches. Most of those situations would resolve on their own in a couple of days. We also give antibiotics many times for people just because they have some sort of a common cold — it's estimated 18 million prescriptions a year — doesn't help anyone who has the common cold. It's a complete waste."
On the rise of antibiotic-resistant bacteria
"It's frightened people for more than a decade. You mentioned at the top the 23,000 Americans who are dying from resistant infections. The CDC said on top of that, there's another 14,000 dying from a horrible disease, intestinal disease, called Clostridium difficile [C-diff] in the United States. Together, that's larger than the number of people who die in this country each year from AIDS. And we're not — as bad as things are now, the more troubling aspects, or what might happen in five or 10 years if some sort of a pathogen was resistant to everything we had got out to the population. It sounds like a Hollywood movie."
You can listen to the full interview here.
Book Review published on SSRN
Three weeks ago I blogged about my recent review of "Pharmaceutical Innovation, Competition and Patent Law – a Trilateral Perspective" (Edward Elgar 2013). The full review, which is forthcoming in a spring issue of European Competition Law Review (Sweet Maxwell), is now available at SSRN: http://ssrn.com/abstract=2396804.
Progress is Possible in the Institutional Corruption of Healthcare
Today, there are two big stories that relate to the "institutional corruption" of medicine (aka conflicts of interests). For those who have been working long and hard on these issues, they are cause for hope. The needle does move.
First, one of the biggest pharmaceutical companies, GlaxoSmithKline, has decided that it will stop paying doctors to promote their drugs. My prior work has shown that such payments are quite common (e.g., 61% of urologists and 57% of gastroenterologists taking money), and that they likely influence the prescribing decisions of the doctors who take such money. In recent months, Glaxo has made several such moves towards greater transparency and integrity, often as a result of threatened or actual criminal prosecutions. (See their newfound commitment to opening up their clinical trial data too.)
The NYT story quotes an industry consultant suggesting that the move to stop paying physicians is a result of the Affordable Care Act's "sunshine" requirement that such payments will be disclosed, and that several other drugmakers are considering similar moves. I am a bit skeptical that the disclosure mandate had such an effect, since the disclosures were already required by Massachusetts and other states, and as part of the "corporate integrity agreements" that came of several federal prosecutions. My sense is that such disclosures are not likely to reach patients in a useable way, so its hard to understand how the transparency could really impose much of a disincentive on the companies. Yet, something has caused Glaxo to change course.
Second, the National Football League has decided to give the National Institute of Health $30 million to study brain injuries. The counterfactual is that the NFL could have kept the money, of course. But the more interesting alternative is that the NFL could have just spent the money itself, hand-picking the researchers and carefully specifying how the research should be performed, in order to buy the scientific conclusions that it preferred. This has been the classic strategy of industries facing litigation risk, from tobacco, to asbestos, and now the paper industry, whose law firm actually commissions scientific studies on its behalf. The NFL's move instead proves that it is possible for a self-interested party to nonetheless fund independent, credible, gold-standard research, by using an intermediary, such as the NIH.
This is exactly the sort of reform that I have called for, as an alternative to the false dichotomy between public funding and private interest. For companies that have a bona fide interest in discovering and publicizing the scientific truth, a credible intermediary like the NIH can reassure consumers of scientific information that it is valid. Now, if only we can get big pharmaceutical companies to make the same move for their clinical trials and other scientific research studies. Perhaps the first-movers will be the most innovative companies who have bona fide products and are tired of them being lost in the cheap talk? If physicians making prescribing decisions continue to give greater credence towards NIH-funded research, such integrity could be rewarded.
EDIT: Corrected link to NFL story on NYT, and corrected amount from $100M to $30M. Also, disclaimer: I am not involved in this Petrie Flom Center collaboration with the NFL, and the views expressed here are entirely my own.
PAPER NOW AVAILABLE for 11/18 Health Law Workshop w/Aaron Kesselheim
Aaron Kesselheim is a physician and an Assistant Professor of Medicine at the Harvard Medical School. He will be speaking at the Petrie-Flom Health Law Workshop on Monday, November 18, at 5:00pm, on "Do March-In Rights Protect Public Interests in Medical Products Arising from Federally-Funded Research?"
For more details on the workshop, including information on how to obtain a copy of the paper, please visit the Petrie-Flom Center's website.
11/7: PRIM&R Session, "Bioethics Funding at the National Institutes of Health"
Looking for a great, informative session about bioethics grants?
Bioethics Funding at the National Institutes of Health
Thursday Nov. 7, 10:30 – 11:45 a.m.
Room 305
- Learn about NIH funding opportunities for bioethics research and scholarship
- Receive helpful tips and tools for the grant application process
- Provide input to NIH staff about bioethics priorities you would like to see funded
- Meet other colleagues interested in bioethics grants
Session panelists | |
Liza Dawson, PhD
NIH/NIAID Division of AIDS |
Joe Millum, PhD
Ann Hardy, DrPH
Sam Garner, MBE
Holly Taylor, PhD, MPH
JHU Berman Bioethics Institute |
Please contact Liza Dawson, email@example.com, with questions.
Unreliable Biomedical Science, and a Solution?
The Economist has a long, detailed, and readable piece about the difficulties of inferring anything from the published findings of biomedical science. There are all sorts of problems that fall short of scientific fraud, including the the biases caused by industry-funding of biomedical science, the biases of unblinded raters who see what they want to see, and the biases of journal editors towards only publishing "positive" findings. (I am particularly enamored with this graphic, which shows the fundamental problem of inference.) It is rare for researchers to even bother to attempt to replicate prior findings, but when replications are attempted, they often fail.
The Economist piece can be read as something close to an outright assault on empiricism, at least as we now know it. In practical terms, it is prudent for physicians, patients, and payors to be wary of the findings presented in even the top journals.
One of the beauties of our scientific system is that it is wildly decentralized. Scientists (and their funders) can test any hypothesis that they find interesting, and they can use whatever methods they prefer. Likewise, journal editors can publish whatever they want. While such academic and market freedom is attractive, it results in quite a hodgepodge of science, with replication studies and publication of null results being afterthoughts. The NIH and NSF have in the past functioned to set an agenda and demand rigor, but as their funding wanes, the chaos waxes.
The problems are scientific, but any solution will be institutional (and thus legal). I have argued for a partial solution to industry bias in my short article, called "The Money Blind: How to Stop Industry Influence in Biomedical Science Without Violating the First Amendment." Independent scientific testing could be conducted by a neutral intermediary, which would pool funds. In a similar vein, there is also a new project of the Science Exchange, called "The Reproducibility Initiative." This program offers to be the independent scientific agency, which attempts to validate known results. But there is not yet a large-scale funding model in place. If biomedical journal editors would at least put disclosures in their structured abstracts (an intervention we have tested), over the long run that may also nudge industry to use such gold-standard independent testing, when they have something that is truly provable. And, at least in the domain of the products regulated by the FDA, the agency should consider using its current statutory authority to push companies towards independent, robust, and replicated science.
Popular Distrust of Health Science: A Crowdsourced Solution
Enjoying the fall foliage in Mt. Auburn Cemetery yesterday, I came across this marker for Benjamin Waterhouse. In the overwrought language that is appropriate on a grave marker: "In 1800 he introduced to the new world the blessing of vaccination. Overcame popular prejudice and distrust by testing it on his own children and thus established a title to the gratitude of future generations."
No less today, there seems to be plenty of popular distrust of elite science. (And it doesn't help that so much of contemporary science is infected by conflicts of interest.) Self-experimentation does have a long venerable history, which has recently become more prominent in the quantified self movement. (I'm not sure about experimenting on my kid though.)
Tomorrow, I'm heading to NYC to make a pitch to the Robert Wood Johnson Foundation's Pioneer Fund, for major funding to launch a new project that would create a platform for robust, randomized experiments of lifestyle interventions (think: migraine management, diets, exercise regimens, nutritional supplements) for which there is virtually no FDA oversight and thus no regulatory imperative for rigorous scientific investigations. Nonetheless, these lifestyle factors are the primary drivers of health and healthcare costs. By crowdsourcing these sorts of experiments in an sound ethical framework robust against institutional corruption, I hope to develop gold-standard scientific knowledge with huge samples, but also build public engagement, public understanding, and public trust of health science.
The crowd uses Wikipedia to organize knowledge, and Indiegogo to invest in new health devices. The crowd needs a platform to create knowledge too, especially through randomized interventions, which have the potential to actually change behaviors for the better and eliminate the confounding factors that undermine observational studies.
So, wish me luck in NYC tomorrow: http://bit.ly/pioneerpitch
Government Shutdown: Why the Pipeline Matters
Much attention has been paid to the government shutdown that started last week. Many of us heard heart-tugging stories on public radio about the NIH closing down new subject enrollment at its "House of Hope," the clinical trial hospital on the NIH main campus. These stories gave many people the impression that clinical research halted around the country when the federal government failed to approve a Continuing Resolution.
The reality is both less dramatic in the short term and more concerning for the long term. For the most part, federally-funded projects at university campuses and hospitals are continuing as usual (or, the new "usual," as reduced by sequestration), because the grants already awarded are like I.O.U.s from the government. By and large, university researchers will keep spending on their funded grants, with the knowledge that reimbursement will come once the government re-opens for business. The universities and hospitals are, in a sense, acting like banks that loan the government money while waiting for these expenses to be reimbursed.
Also, many clinical trials are funded by the pharmaceutical industry. So it is not the case that hospitals are closing their doors to research en masse. But the long-term effects of a shutdown will have lasting and compounding effects on our science pipeline. The U.S. federal government is the single largest funder of scientific research at American universities. Each month, thousands of grant proposals are sent to the various federal funding agencies for consideration. These in turn are filtered and assigned to peer review committees. The whole process of review, scoring, and funding approval typically takes months, sometimes more than a year.
Under the terms of the shutdown, the staff who normally receive and triage these grant proposals are considered non-essential. All but one of the federal grant on-line submission portals have been taken off-line. So thousands of researchers who had been working for months to write grant proposals for funds needed to conduct the next generation of studies are now left wondering when it will be possible to submit for agency review. Those studies hold the keys to future discoveries that could bring needed cures to the bedside, important products to the marketplace, and new jobs into the economy. Continue reading
"How I Stopped Worrying and Learned to Love Test Tube Meat (and Started Thinking It May Be Immoral NOT to Eat It)" Or "Hooray For Chickie Nobs!!??!!"
If you were watching television this week you may have seen this clip of a taste test for hamburger meat grown in a "test tube" in London discussed here. The meat was grown from stem cells from existing cows used to grow 20,000 strands of tissue. Costing more than $330,000 to make, with funding by google Co-Founder Sergey Brin, the day where this will be available at your grocery store or served at your fast food franchise is far away. But it may come sooner if we conclude that there may be a moral duty to develop and eat this kind of meat rather than animal-grown meat and press our governments to start funding this work. What is the morality of test tube meat consumption?
Sometimes narrative can be a way into ethics so consider this bit from one of my favorite novelists (and Canadian public intellectuals) Margaret Atwood from her novel Oryx and Crake. She imagines a dystopian future that includes the the consumption of "Chickie Knobs" in one scene:
"This is the latest," said Crake.
What they were looking at was a large bulblike object that seemed to be covered with stippled whitish-yellow skin. Out of it came twenty thick fleshy tubes, and at the end of each tube another bulb was growing.
"What the hell is it?" said Jimmy.
"Those are chickens," said Crake. "Chicken parts. Just the breasts, on this one. They've got ones that specialize in drumsticks too, twelve to a growth unit.
"But there aren't any heads…"
"That's the head in the middle," said the woman. "There's a mouth opening at the top, they dump nutrients in there. No eyes or beak or anything, they don't need those."
To be clear the test tube meat unveiled earlier this week is not a Chickie Nob, it is grown from stem cells rather than being a cow with extra parts and brains missing (Atwood is silent on some characteristics of the Chickie Nob that may matter ethically such as whether it feels pain or is sentient), but I think many will react to the test tube meat the same way: disgust. Some in bioethics, like Leon Kass, think there can be a "Wisdom of Repugnance." In my own work I have been a persistent skeptic on this theme. For me repugnance and disgust are good and should be cultivated as reactions for that which we deem immoral, but should be broken down and overcome for those things which we conclude are morally worth pursuing. Thus repugnance is a tool whose proper deployment depends on prior moral conclusions. In the case of test tube meat, whatever repugnance we feel is one we should get over and media, government, etc, should help us do so.
"Measuring the Un-measurable"
By Scott Burris
A couple weeks ago, I was in a conference room at a global health organization, all ready to give my talk on monitoring and evaluating legal health interventions. The chief of the organization's formidable M&E operation was my host, and after briefly going through my bio he wound up his introduction by describing me as "the guy who will be telling us how to measure the un-measurable."
In that one flourish, he captured the biggest barrier to more and better research on the impact of laws and legal practices on health: the cultural belief that law is different from other forms of individual and institutionalized human behavior and belief, so that it, alone, must perforce remain an evidence-free zone. This is certainly a tragedy of low expectations if ever there was one. Uncertainty is part of any hard decision, but if people in the organization I was visiting were talking about defining the optimum treatment regimen for a particular disease, they would take for granted that the deliberations of the decision-makers would be guided by a substantial evidence base. Yet when the question is what package of laws and legal practices create the best environment for preventing the same disease, or encouraging people to seek treatment, they see nothing strange about proceeding entirely on intuition and experience.
As Evan Anderson and I have recently written, the importance of law to health, and the overall success in properly evaluating its impact, belie this continued cultural prejudice. Law can be hard to evaluate, but so are most other influences on our behavior and environment. In a number of areas of legal intervention, researchers have found ways to measure the hard-to-measure and produce credible findings that have shaped policy. They have done so in ways that respect the prosaic realities of practical science work: developing reliable measures and data and deploying them within robust designs is not the work of individuals, it's not cheap, and it is not quick. Where legal evaluation has thrived, it has done so because enough money was available for long enough to support multiple lines of inquiry by multiple teams of researchers. Careers, or stands of careers, could be built, and competition and disagreement could drive rigor and relevance.
This week, PHLR is celebrating one very tangible result of investment in the field: the publication of Public Health Law Research: Theory and Methods, which was conceived by the PHLR Methods Core and edited by Alex Wagenaar and me. The book, which was written both as a methods class text book and a general reference work, is an important piece of field-building, in that it tries to define the basic good practices of PHLR. But I think it does more: Alex, whose work on crash law exemplifies all that legal monitoring and evaluation can be, has led the production of a book that we can drop on the desk of every person in every funding and health services organization who thinks that measuring law is measuring the un-measurable.
Politics and Science
By Joanna Sax
On April 29, Scott Burris blogged about a new bill that would allow Congress to set the scientific agenda, which would replace the traditional peer review process. I echo his expressed concerns, but want to add more. The idea that politicians, and not scientists, could determine the advancement of science is, frankly, a disaster. In the past we have seen political leaders spar with scientists over many things – such as whether the earth is round, whether the earth is the center of the universe, etc. If scientists did not or could not answer those questions, we might think we are walking on a flat earth.
Even now, there is a strong interaction between politics and science. Evolution, a scientific theory with unequivocal consensus among the scientific community, still faces political opposition. Recently, I've been thinking and writing in this area, that is, the interaction of politics and science. Questions for scientific inquiry should be determined by scientists. How we allocate and manage our resources requires, as others have argued, experts in many areas, including economics, management, and public policy.
To look at the interaction of science and politics, I conducted an empirical analysis comparing the type of information communicated to the public versus the consensus in the scientific community to determine whether politics is playing a role in scientific inquiry. The study centers on the debate regarding the funding of embryonic stem cell research. If you are interested in this area, please check out a recent draft here. It's an early draft and I welcome comments – you can email comments to me at email@example.com


text:
THE GIFT OF PETS by Bruce Coston; and BLACK DAHLIA & WHITE ROSE: STORIES, By Joyce Carol Oates
There's wonderful material in this veterinarian's memoir, with stories ranging from heartbreaking to funny to bizarre. (Be warned: There are nauseating chapters, too. Removing pieces of a tennis ball from a rottweiler's intestinal tract is not a pretty business.) Bruce Coston remembers a grade-schooler who used his allowance to pay for cancer surgery for his beloved pet rat, knowing that it would buy the animal just a bit more time. He hilariously describes his teen experience shadowing cattle and horse vets in Minnesota. (Cleaning out a cow's innards is not pretty business, either. He opted for pet medicine instead.) Unfortunately, the storytelling doesn't measure up to the material. The author is clearly a great vet, but he tends to overwrite, peppering his stories with exclamation points and lengthy descriptions that distract from the humor, love and grief he observes every day. Pet lovers and those interested in vet work will forgive the flaws, though, and will savor the stories Coston shares.
In yet another collection of raw, spooky and captivating stories set in troubled cities, families and psyches, Joyce Carol Oates demonstrates again that she is one of the nation's greatest writers. No one writes like her; no one so boldly explores the naïveté, narcissism and cruelty that lurk at the edges of many American lives and souls. In the title story, she returns to one of her obsessions, Marilyn Monroe, who as a young Norma Jeane Baker frets over the risks taken by her imagined 1940s roommate, Elizabeth Short, soon to be known as "the Black Dahlia," the infamous victim of a particularly horrific murder. In others, teenagers and adults with pinched lives work hard to shore up facades that fool no one but themselves. Yet as grotesque and even repulsive as some of Oates' characters can be, they are rendered with her distinctive muted compassion. And the most startling thing of all about them is that we've met these people; sometimes, we are these people. Oates' genius imagination is matched only by her mighty powers of observation. Many critics say Oates writes way too much, but this faithful reader says she can't possibly write enough.

subset: commoncrawl


text:
Fujifilm 20-Pack Instax Wide Instant Color Print Film, ISO 800
Ways to Save
Why Adorama?
Easy Returns, Fast Shipping, Trusted for over 35 years.Need help? Call 800-223-2500 212-741-0052
Get the best value shopping our selection of used gear.
Shop UsedWe Pay top dollar for your used photo & video equipment.
Get A QuoteNeed help? Call 800-223-2500 212-741-0052
The Fujifilm Instax Film is an incredible ISO 800 film made for use in Instax series cameras. The film has a glossy finish and is an excellent choice for general use, portraiture or even with electronic flash. The film prints ultra sharp for an 800 speed film making it extremely useful in low light scenarios. It is also enhanced to maintain its stability over the years making it a good choice for archival storage.
The Fujifilm 20-Pack Color Filter is commonly used for Parties, Photography and more.The Fujifilm 20-Pack Color Filter is most used by customers who consider themselves to be a Casual photographer, Photo enthusiast among others.The Fujifilm 20-Pack Color Filter is popular because customers like the following qualities of the Fujifilm 20-Pack Color Filter: Consistent and Fast film loading.
Type | Instax |
Speed | ISO 800 |
Applications | General purpose photography |
Color Saturation | Excellent |
Process | Instant |
Grain | Very fine |
Sharpness | Very sharp |
Warranty | Fujifilm warranty |


text:
Learning to Speak Alzheimer's: A Groundbreaking Approach for Everyone Dealing with the DiseaseJoanne Koenig Coste, now a renowned pioneer in implementing positive methods of caring for Alzheimer's patients, began to develop her groundbreaking approach when her middle-aged husband was diagnosed with progressive dementia shortly after the birth of her fourth child. As she struggled to care for him and their family, she recognized that it was possible to avoid some of the tremendous emotional burdens Alzheimer's patients and their care providers endure during the course of the disease. In this book Koenig Coste explains the five tenets of her "habilitation" approach, an accessible and comprehensive plan proven to have worked with thousands of patients and care providers. Refuting long-accepted ideas, she calls for care "partners" to join patients in their current sense of place or time; to encourage patients to use their remaining skills to support their sense of independence and dignity; and, most of all, to continue communicating with patients by focusing on their emotional "language." Learning to Speak Alzheimer's also offers hundreds of practical tips to ease life for everyone involved with Alzheimer's, including how to - cope with the diagnosis and figure out if the patient wants to discuss it - respectfully stop the person from driving - make meal and bath times as pleasant as possible - adjust room design and lighting for the patient's comfort - deal with wandering, paranoia, and aggression - establish a plan of care Learning to Speak Alzheimer's revolutionizes the way we perceive and deal with Alzheimer's disease. |
What people are saying - Write a review
User ratings
5 stars |
| ||
4 stars |
| ||
3 stars |
| ||
2 stars |
| ||
1 star |
Review: Learning to Speak Alzheimer's: A Groundbreaking Approach for Everyone Dealing with the Disease
User Review - Kathy - GoodreadsThis book had valuable insights, it is such a terrible disease, see my dad slipping away Read full review
Review: Learning to Speak Alzheimer's: A Groundbreaking Approach for Everyone Dealing with the Disease
User Review - Dennis - GoodreadsThis is an excellent book for anyone who will interact with an Alzheimer's patient - family or friend. My mother has some dementia (probably not Alzheimer's) but I found the book really helpful as her ... Read full review


text:
In every part of our vast country you'll find unique experiences to make your dream holiday come true.
The Gold Coast is the 'theme park capital of Australia' with plenty of choices to appeal to all ages. From the world's tallest and fastest thrill rides, to parks where you can see native Australian wildlife, or splash around in swimming pools and water slides; you'll find it all on the Gold Coast. Meet your favourite movie characters and super-heroes; or swim with dolphins and sharks. Explore the rainforest canopy; or find eggs from when dinosaurs roamed the earth. Cuddle a koala; feed kangaroos and meet colourful native birds. There's also plenty of indoor entertainment, from futuristic attractions to museums.
Dreamworld is Australia's largest theme park and is like visiting multiple worlds in one. Dreamworld features an assortment of rides, shows and attractions, including The Tower of Terror 2, one of the tallest and fastest thrill rides in the world. Visit Tiger Island, where magnificent Bengal and Sumatran tigers play with their keepers. On the 'Australian Wildlife Experience' you can see more than 500 Australian native animals. Challenge yourself on the Flowrider – the perfect combination of surfing, skateboarding and body boarding. Dreamworld is right next door to WhiteWater World.
WhiteWater World has some of the best water attractions in the world, including the top four water slides. Hire a private cabana for your family and cool off from the tropical Queensland heat. Surf lessons are held Cave of Waves under lights after the park closes, several times a week.
Wet'n'Wild Water World is Australia's biggest water theme park and combines the latest in fun-filled water slides and leisure pools for all the family. Plunge seven stories down a speed coaster or simply laze in the giant wave pool. There's also around 20 acres of shaded subtropical gardens for relaxing.
Warner Bros. Movie World is where your favourite movies come to life. Meet the stars and go on thrilling rollercoaster rides such as the Green Lantern Roller Coaster and Superman Escape and others based on your favourite Warner Bros. movie characters and super-heroes. At the Kids' Fun Zone meet your favourite Looney Tunes characters including Bugs Bunny and Daffy Duck.
Sea World and has been a family favourite theme park for over 35 years. Sea World has more than exciting rides, attractions and shows. It is also committed to marine research and rescue, and a place where visitors can learn about and make contact with a variety of marine animals. See the delightful Dolphin Discovery show; polar bears and penguins swimming underwater; and get up close to a fearsome shark. Linked by monorail to Sea World theme park, Sea World Resort and Water Resort is Australia's only theme park hotel.
Those seeking futuristic games and indoor family entertainment should try Infinity; Timezone; Ripley's Believe It Or Not Odditorium; or Dracula's Haunted House. The Gold Coast Wax Museum is listed as one of the Great Wax Museums of the World. It's the largest Australian museum of its kind and features life-size wax figures, copies of the British Crown Jewels and dioramas of Australian history. Experience the spirit of the Australian outback at the Warner Brothers Australian Outback Spectacular. Be dazzled by wild horses, stampeding cattle, and an unforgettable display of horsemanship.
In the Gold Coast hinterland you can explore the rainforest canopy on the Tamborine Rainforest Skywalk. Thunderbird Park on Tamborine Mountain has walking tracks, hundreds of birds, Australian native animals and rare plants. Find 'thunder-eggs' formed when dinosaurs roamed the earth; tackle the high ropes on the Tree Top Challenge or enjoy the horse-riding trails through the rainforest. Scale the treetop course at Adventure Parc at Currumbin Wildlife Sanctuary where you can also cuddle a koala; feed a kangaroo and colourful wild lorikeets. At Tropical Fruit World you can taste more than 500 varieties of weird and wonderful exotic fruits.
More Australian Ideas
Gold Coast
Great Barrier Reef
Three Great Days on the Gold Coast, QLD
Plan Your Visit


text:
Hello Everyone,
I am the owner of a 2001 Toyota Tacoma with a 1st generation supercharger, TRD headers and a AEM Brute force intake. I have recently noticed some degradation in boost pressure over the last few months and was wondering if you all had some insight into some areas to look for problems. Currently the boost gauge is only registering about 4-4.5Lbs of boost when I push it as hard as possible. I was pretty sure when I got it that is was putting out more like 5-6psi when I got the Truck. The car is equipped with the TRD dynamic tensioner and I just replaced all my belts, washed and rinsed all my pulleys, and checked all my lines for vacuum leaks when I noticed the low boost pressure. The TRD installation manual claims that it is supposed to put out 7lbs psi. What kind of boost ratings are you all getting and where else should I look for issues? The PO claimed that they had the whole supercharger warrantied approximately 30,000 miles ago but there was no paperwork to prove it. The truck runs/drives/idles just fine. Any help or suggestions would be great.


text:
King James Version (KJV) | New International Version (NIV) |
12 I know that the LORD will maintain the cause of the afflicted, and the right of the poor. | 12 I know that the LORD secures justice for the poor and upholds the cause of the needy. |
The King James Version is in the public domain. (The King James Bible Version Online) | Scripture quoted by permission. Quotations designated (NIV) are from THE HOLY BIBLE: NEW INTERNATIONAL VERSION®. NIV®. Copyright © 1973, 1978, 1984 by Biblica. All rights reserved worldwide. (New International Version Bible Online) |


text:
First batch ever making eomuk!
Have a cool photo you want to share?
14 more photos of eomuk:
Korean fishcakes made with chicken ^^
photo by Wenni
First time Eomuk – A success!!
photo by RamandaSpicyPassion
Homemade Fishcakes
photo by Maangchi
Sandy's homemade Fish Cake
photo by Skates
Fishcake – Eomuk
photo by aTrueRedHead
Eomuk (fish cake)
photo by __sawaa
My Fish Cake
photo by Sunghan
Homemade Fish Cake
photo by stonefly
Fish Cakes
photo by StarryLiz
Eomuk ( Fish Cake )
photo by jaylivg
Spicy Stirfried Fish Cakes
photo by quinnbabe
photo by Kjbehr
Homemade fishcakes
photo by Laifa
photo by Inge
Fish Cake Soup ( Eomukguk )
photo by jaylivg


text:
Current Students
Faculty & Staff
Business Partners
Contact Us
Campus Life
Strategic Plan
Strategic Plan 2007-2012
Enterprise Systems and Process Renewal Project
Where We've Been
» Message from the President, October 2009
Message from the President, October 2009
We live in a time of accelerated change, both social and technological. Higher education continues to become more and more competitive, and the current economic crisis sharpens that competition. Ball State has laid out an ambitious strategic plan that is crucial to the future success of our institution. Much of that success will depend on talented people: faculty, staff, and an increasingly bright and curious student body. In order to reach our common goals, we must provide the members of our community the tools and processes that will support their efforts.
Ball State's core administrative systems have been around a long, long time and have served the institution well. However, in a time of great change, we need systems that can grow and adapt to meet the challenges and opportunities that lie ahead.
When David Letterman returned to his alma mater for the dedication of the Letterman Communication and Media Building, he commented that he was "old" media, that the future of communications was represented in the state-of-the-art facility where we would be developing the next generation of communicators and leaders. In much the same way, it is time for Ball State to examine our "old" administrative systems—and ways of doing business—and move forward to the next generation of approaches and applications that will help us achieve our strategic goals.
Over the past year and a half, the vice presidents have worked together to evaluate our current state of business processes and systems. They recommended to me that we begin a process of renewing—and replacing—our core enterprise systems. They have recommended a rigorous process of assessment and evaluation, and I concur with their recommendations.
This is no small undertaking. The size and complexity of the project is challenging, and the resource demands will be significant, but this project is also crucial to the continued vitality of Ball State.
This is not a narrow administrative or IT project but truly a university-wide priority. This is not so much about administrative systems but rather ways of doing business. I am confident that working together as a community we can be successful.
Jo Ann M. Gora, President
October 1, 2009
Where We've Been
Message from the President, October 2009


text:
Comfort and range
The A350-800 is the shortest fuselage version in Airbus' new A350 XWB all-new family of mid-sized widebody airliners. It accommodates 276 passengers in a typical two-class cabin, with a flight range of 8,250 nautical miles.
A shortened variant of the family's cornerstone A350-900, the A350-800 retains maximum commonality with family's other versions, with the same cross section, cockpit and pilot type rating – along with common engines, systems, operating and maintenance procedures.
Its extra widebody 220-inch interior cross-section is five inches larger than the nearest competitor. This provides the additional space for integrating innovative premium class solutions at up to six- or seven-abreast seating, while providing airlines with the advantage of comfortably accommodating economy class passengers at eight-, nine- or 10-abreast arrangements.
The A350 XWB's wide fuselage cross-section was designed for an optimum travel experience in all classes of service. Passengers will enjoy more headroom, wider panoramic windows and larger overhead storage space. With a cross-section of 220 inches from armrest to armrest, the jetliner's cabin provides the widest seats in its category, being five inches larger than its nearest competitor. In addition to providing the space for unmatched premium first class and business solutions, the A350 XWB allows for high-comfort economy seating in a nine-abreast arrangement, with a generous 18-inch seat width.
Over 70 per cent of the A350 XWB's weight-efficient airframe is made from advanced materials that combine composites (53 per cent), titanium and advanced aluminium alloys. The innovative carbon fibre reinforced plastic fuselage results in lower fuel burn as well as easier maintenance. With this new fuselage – along with the latest systems and engines, as well as an advanced wing optimised for Mach 0.85 cruise speed – the A350-800 is a step ahead of its direct competitor, benefitting from an eight per cent lower fuel burn, eight per cent lower operating costs, and eight percent lower CO2 emissions.
Fly-by-wire continuity
As with the other A350 Family members, the A350-800 utilises Airbus' fly-by-wire controls for excellent handling characteristics and protection throughout the flight envelope. Its flight deck features six large identical, interchangeable instrumentation displays as an evolution of the A380's configuration. This preserves the maximum commonality with other Airbus jetliners, allowing crews to benefit from cross crew qualification and mixed fleet flying with the A320, A330, A340 and A380 families.


text:
Sign In to Your Account
Shop The Large Selection Of All Magtech .45 Colt Ammo At Rock Bottom Low Prices...Guaranteed at Sportsman's Guide
Remington® .45 Colt 250 Grain Lead RN Target
Glaser® Blue #12 Shot Safety .45 Colt+P 145
Federal® Champion® .45 Colt 225-grain Semi Wadcutter HP,
Hornady® .45 Colt® 225 Grain FTX™ 20 rounds
Item not currently available for sale.
50 rds. Remington® Target Pistol / Revolver Rounds. Perfect for practice, so your aim is when it counts (perfect, that is).
You know what they say about practice. Do it to perfection with Remington Target Pistol / Revelver Ammo. Consistency, accuracy and iron-clad reliability, made with high-quality components and available in all traditional revolver bullet styles. For the quality wheelgun owners demand, Remington Target delivers.
Order ONLINE Now!
More Details...
Glaser® Blue & Silver Safety Ammo
Glaser® Blue uses #12 shot in its core to provide exceptional ricochet protection. Glaser Silver uses #6 shot in its core for slightly higher penetration.
Glaser patented safety slug, with a special jacket and a compressed shot core with a plastic tip. It's 100% guaranteed to feed reliably. Safe to use in all modern firearms. 6 per box.
GBSA = Glaser® Blue Safety Ammo
In Stock
Federal® Champion® Loads Great bullets for target practice!
Hone your aim with these target loads for a great price!
Hornady® LEVERevolution® Ammo, "100 years NEW!"
Its higher ballistic coefficient delivers flatter trajectories for fantastic downrange energy, bullet expansion and accuracy.


text:
Reader comments are listed below. Comments are currently closed and new comments are no longer being accepted.
While these two shrewd chess players are pitted in their delicate match, public approval of their institution is circling the drain.
There's always bipartisanship. The parties just colluded on the terrible idea of throwing federal money at local airports, in key districts. There is a bipartisan effort to jack up the cost of dental care. The farm bill passed in a bipartisan vote. The parties have an otherwise unusual ability work together when it comes to making congressional districts as uncompetitive as possible. There's plenty of bipartisanship I could use less of.
"People of the same trade seldom meet together, even for merriment and diversion, but the conversation ends in a conspiracy against the public, or in some contrivance to raise prices." - Adam Smith
Reid is at least an intersesting fellow.(Sourpuss) McConnell is so predictably antediluvian a conservative. It would be worthwhile to study his record during the Bush Jr. years. He has shown precious little leadership.
The really odd couple is McConnell & Boehner. One always in tears, the other unable to crack a smile.
Indeed, not to mention the republic itself.
Our House rep has been in Congress forever, is high in the GOP leadership, and is dumb as a post.
I was in a small meeting with him and a few local business leaders a few years back, five folks around a table, and it was clear that our Rep was the dumbest guy in the room.
I spoke with another participant about it later, and he said that that was why he ended up in Congress, i.e., it was his best financial option given his skill-set, or lack thereof.
"Mr Reid, for his part, did not give in to the hotheads in his party who wanted to use yet another procedural manoeuvre to make it much harder to filibuster."
In what world is that an act of pragmatism, and in what world is that the work of 'hotheads'? I really don't follow how continuing to hold the bar at 60 votes for the purpose of defending his own power counts as pragmatism, and how being frustrated at the utter sclerosis of the modern senate makes one 'hot headed'
The original text is correct. Do a bit of research on the anglosaxon genitive.
Two children squabbling over half a candy bar they found underneath the couch cushions would be a more appropriate graphic in my opinion.
Well, I'd just respond with the following, per my cranky theme of this morning -
The best way to be healthy and financially successful in America, from what I can tell, is to move out of a GOP-controlled state :) -
The most recent attempt by a senator to derail a Flood Insurance Bill with an abortion amendment was certainly a test of that pragmatism.
Harry Reid is basically spineless and Mitch McConnell has virtually single handedly obstructed the entire Obama term with more filibusters under his watch then the past 60 years combined. Reid should be sacked. McConnell should be in jail for ruining the nation.
I think its humorous to listen to the individuals take shots at EITHER Reid or McConnell calling one better than the other. Seriously we as Americans champion too hard and become so vested in our politicians and respective parties, as if they were your pick of a national sports superstar on your favorite team. Democrats say conservatives are the losers and vice versa. As if being tied to a party and having your party win vindicates your beliefs. Reid and McConnell , liberals vs. Conservatives , it doesn't matter they can't be popular without each other kind of like the yin AND the yang they need each other. It seems in a time that we as a nation is becoming more polarized, do you really think these polticians fight like us when they aren't in public...no of course not they are all sipping on expensive spirits laughing like old pals I bet. They are nothing like the typical American...but they are sure loving us buying into thier rhetoric to solidify thier popularity in thier respective party. In sum the system is designed, not to mention funded by corporations to ensure a somewhat politically stable centrist environment but hey you all keep rooting for your respective heros if it makes you feel better.
The article is about the Senate. You can't make Senate districts less competitive by any means other than moving state lines.
"Mr Reid has adopted an old slogan of Harry Truman's....". Harry Truman's what? Oh, you mean an old slogan of Harry Truman? English dear boy, English.
Actually, that's the second-best way. The best way (unless you happen to have lots of talent which is prized by a financial firm or something) is to get elected to Congress. No entry requirements, no talent required, just lots of perks and people giving you money (nominally not tied to anything you have done for them). And once you have done it, you can get lobbying firms to lavish yet more money on you.
Sen. McConnell is a throwback to days of Senate yore, when a Southern senator might cane a detractor.
Except that McConnell is so bloody old, that he'd probably throw out his back...
I think Smith's observation needs a small amendment.
"People who run businesses in the same trade..." I frequently see technical people get together and the talk is about how to do the stuff that they do better. Lots of cooperation, but not on how to make more money out of what they do.
Which, I suppose, says something about the differences in the mindsets between those who manage and those who work for a living.
In 1914 trench warriors created a Christmas truce in parts of the Western Front. Afterward the slaughter resumed. Unless cooperation counts as much as partisan warfare, the Senate and House are doomed to see ever lower approval ratings. The party which has the highest percentage of representatives who follow the party line should be viewed with the greatest suspicion.
In a just world, Reid and McConnell would be cellmates...
If McConnell is Andrew Butler, then who is Preston Brooks? Any Kentucky GOP nutjobs in the House up to it?
Anti-Semitism and free speech: Outlawing intolerance
Graphic detail
The Philippines' peace process: Bungling into bloodshed
Press freedom and national security: Why locking up leakers makes sense
Democracy in America
The Economist explains: Saudi Arabia's dress code for women
The Economist explains
Epidemiology: Virulent encounters
Science and technology
Consumer-goods firms and advertising: The dangers of cut-price soap
Business and finance
Have you listened to The Economist Radio on Facebook?
The Economist Radio is an on-demand social listening platform that allows you to listen, share and recommend The Economist audio content
Test your EQ
Take our weekly news quiz to stay on top of the headlines
In Other Words
Try our new audio app and website, providing reporting and analysis from our correspondents around the world every weekday
Want more from The Economist?
Visit The Economist e-store and you'll find a range of carefully selected products for business and pleasure, Economist books and diaries, and much more


text:
Spring Valley is a populated place LOCATED WITHIN the City of Noel. In turn, the City of Noel is located within McDonald County.
Spring Valley is located at latitude 36.552 and longitude -94.5. The elevation of Spring Valley is 814 feet above mean sea level.
Since Spring Valley is located within the City of Noel, all of the census and demographic data for residents of Spring Valley are included as part of the information reported for City of Noel in the "Data" tab above.
In similar fashion, ALL OF THE NAVIGATION TABS ABOVE ARE FOR THE City of Noel Community Profile.
McDonald County: Cities & Towns | ZIP Codes | Schools | Features (airports, churches, hospitals, etc.)
BIG Map |
Driving Directions |
Data Source - USGS GNIS FID: 754355
BOUNDARY MAPS: City of Noel | Township of Elk River West | McDonald County
The Demographic Data for the 3,542 Missouri cities, towns, counties, ZIP Codes and Census Designated Places (CDPs) profiled in this gazetteer is updated annually. Last Update: July 1, 2014.
The ZIP Code maps and the data regarding the number of residential and business addresses in each ZIP Code are updated four times per year. Last Update: November 1, 2014.
The information on the 56,553 Missouri Physical, Cultural and Historic Features is updated six times per year. Last Update: December 2, 2014.
The School Attendance Zone Maps for 2,256 Missouri public schools are updated four times per year. Last Update: October 6, 2014.


text:
Quoted from Jane Get some Catechol (sp?) for yourself. That will help with the anxiety. Years ago there was someone on these boards. He was from Germany I think and he swore that rice and Maine blueberries saved his life when he had IBD. He lived on just that for a while. I have it too, have had it for many years and been following O diet since the mid-90s. Some veggies do bother me - too many carrots for one thing. When I was first diagnosed in 1994 before I found BTD, doctor wouldn't allow me any veggies, not even baby food veggies. Thinking has certainly changed since then and I eat most things that are O compliant. One of these days I'll get to Bridgeport and get a Pro SWAMI. I feel best on lean buffalo - I buy the fresh ground at WFs and add seasalt and ground garlic and grill it. If I want a sandwich, I use the Food for Life breads - mostly the Bhutanese Red Rice or the Black China Rice. If I can't find them which I haven't been able to lately at my local SFs, I buy the millet/rice. You have to toast them but they don't fall apart like most GF breads. I never had to go on the steroids. I take an English drug called IC Balsalizide (much cheaper than the ASAs) and the Canasa Suppositories. They help a lot.I wish you son the best. By the way, Dr. D once recommended I try something called Seacure - it's made from Whitefish. Bought it once but I didn't see much difference. You can google it to find it. Maybe it will help your son.
Quoted Text it was what I was I isolated that they should consume that would make them better."
Quoted from misspudding It's so frustrating. I hate seeing him in pain and just want him to feel better right now.
Quoted from misspudding Technically, his poops aren't liquid, but he's just having such urgency and frequency...it's not "normal". After 2 years of constipation, this is just such an odd problem to have.
Quoted from Mother None of the fiber type things work for me at all. I know other forms of magnesium are recommended but mag oxide works all the time. 750 mg, I think it's Natures Bounty from Walgreens or Walmart. Cheap and VERY effective. Take just before bed with a glass of water. It is the only thing that works consistently. It might take 2 or 3 days for results and then you are home free.
Quoted from A HealthNut For healing the stomach I have read that pre digested fish capsules have had good results. I need healing and would like to know if anyone(especially A's) have any feedback on this.
Quoted from A HealthNut My other concern is for a additional fiber... what is a good supplement to help in this area. I know you are going to respond by saying eat more fiber foods which I do as a vegetarian diet but I still need a supplement so please help with this.
Quoted Text [Are you talking about Seacure?
Quoted from Jane MissP,Is the SNP rs3024505? I'm GG for that which indicates homozygous right?
Quoted from Mother Senna KILLS me but so does psyllium .
Quoted from Jane Poor kid and so hard on you too. Have you ever tried the suppositories like Canasa or are they too far down to help. They help me more than anything.


text:
found a new home!
Plenty of my friends are looking
for one too. Find a pet to adopt.
Find a pet to adopt |
My name is Donovan!
Facts about Donovan
- Breed: Cocker Spaniel
- Color: Red/Golden/Orange/Chestnut
- Age: Young
- Size: Small 25 lbs (11 kg) or less
- Sex: Male
Donovan's Info...
I am already neutered, purebred, a special needs pet, and up to date with shots.
Donovan is a two year old male. He has such a handsome red coat, he's frequently called Redmon around his foster home. Donovan is an active, alert fellow with a touch of obsessive-compulsive disorder. Seriously. He's taking busprione twice a day to help him focus. Donovan
Other Pets at Cocker Spaniel Rescue of East TX
Why Adoption is a Great Option
Donovan, a Houston Cocker Spaniel dog was adopted! Here's how you can benefit by looking at adoption as an option to buying a Cocker Spaniel for sale in Houston, or seeking a Cocker Spaniel dog from a breeder in Houston.
- Rescues and shelter volunteers in Houston already know the personality and tendencies of their pets. This means they can match you with the right pet. That will makes it much easier transition to owning a pet for yourself and your new pet.
- On average adoption fees are much less than you'd pay a Houston breeder, or pet store. Plus most often rescue pets have already been to the veterinarian for a check-up, had a round of vaccinations, and are spayed or neutered. That is a lot of savings!
- You will become a hero, and give a needy dog or cat a loving home. In fact, there are even Cocker Spaniel breeders who help with Cocker Spaniel rescue. One puppy or kitten adopted in Houston paves the way for another one to be saved.


text:
'Scandal' Recap: Olivia Gets Outmaneuvered By Her Father
This week's episode of "Scandal" delved deeply into Olivia's Daddy issues. Full recap — plus, watch the entire episode …
This week's episode of "Scandal" delved deeply into Olivia's Daddy issues. Full recap — plus, watch the entire episode …
The Season 2 finale of "Scandal" left fans gasping and tweeting in shock: Jake (Scott Foley) was thrown in the hole, Quinn (Katie Lowes) embraced her new role as torturer,… More
Kerry Washington is not Olivia Pope. Both women are smart, driven, and passionate about their work. But Olivia Pope, the character Washington plays on "Scandal", would never wear suede high… More
The conspiracy grows bigger on Thursday night's episode of "Scandal" as we discover in flashbacks a lot more about what happened with the rigging of the presidential election — and… More
ABC's 'No Ordinary Family' hasn't even premiered yet, and already it's sparking up a mini 'Weeds' reunion for cast member Romany Malco. Guesting on the soon-to-premiere action-dramedy will be Guillermo… More
Your hub for all the personal finance news that affects you and your family.
A blog about health, food, beauty, fitness, fashion, parenting and travel focused on how we, as individuals and as a society live our lives.
A blog keeping you up to date on the most popular news across the web.
An up-to-the-minute blog covering celebrities, gossip and entertainment news.
Covering the latest news, opinions and analysis across the world of sports.
A blog about television, characters, programming, actors, and the business of the small screen.
A blog about movie news, movie stars, movie premieres and the business of the big screen.
About music, artists and the news that envelops the industry.


text:
From The Print Section :: Page 178
Jane Lee Ball
Jane L. Ball died on Monday, March 28. She was 81.
Daniel Daley Hotaling
Daniel Daley Hotaling died Tuesday, March 28, surrounded by his family at the Tidewell hospice center in Venice, Fla. He was 82.
Rahmanian an Antioch College academic leader
Longtime Antioch College faculty member and former Nonstop leader Hassan Rahmanian has been named the revived college's new dean for curriculum, assessment, planning and interdisciplinary learning.
Bill Hooper
William (Bill) Hooper, well-known contractor, former Antioch and Miami Township trustee and local activist, died March 25 at Greene Memorial Hospital in Xenia. He was 91 years old.
Expressing the inexpressable through dance
Movement can convey more emotion than words. Just watch dancer and choreographer Tricia Gelmini, whose piece at this weekend's community dance concert will blend sorrow and joy in an expression of loss.
Village offers support
At the meeting, Village leaders pledged their support to do what they can to ensure that YSI continues to stay in Yellow Springs.
Nonstop examines Progressive arts in small towns
Does being an arts town mean just producing art, or also encouraging the questioning of and critical thinking about the dominant culture that artists tend to provide?
Minister passionate about justice
Now preaching from the pulpit of the First Presbyterian church, new pastor Joe Hinds has a Southern accent and a passion for social justice.
State cuts have local budget impact
Local institutions are reeling from the release of Gov. John Kasich's biennial budget last week, which proposes funding cuts for local governments, schools, libraries and elder care facilities.
Council moves ahead with housing
Villagers offered a robust show of community support for Village Council's proposed affordable housing project at Council's meeting Monday, March 21, when Council unanimously approved moving ahead with the first of three steps for the housing project.


text:
Vivas Guesthouse & Schiller Park Suites
The Vivas Guesthouse is an inviting and relaxing home located in Historic German Village. It is moments away from Schiller Park. German Village is a quiet, urban, friendly neighborhood that is listed on the National Register of Historic Places and was recognized as a Preserve America Community. Located south of downtown Columbus, this lovely historical neighborhood offers so much to its visitors. Enjoy strolling the brick streets while surrounded by beautiful homes and gardens. Indulge in fine dining by visiting restaurants like G. Michaels, Lindey's and Barcelona. They are all close to the Vivas Guesthouse. Continue your walk or bike ride to Third Street and visit the many small businesses that thrive in this unique community. The Downtown Loft is a two story cozy residence... a true boutique experience. Located within minutes of Schiller Park, you are steps away from some of the best restaurants and bars in town as well as Columbus landmarks. Minutes away from Short North, OSU, River Side and German Village.
Vivas Guesthouse sleeps up to ten people - The first floor has a living room, dining room, 1/2 bath and a large, fully stocked kitchen with a great island for entertaining friends. The second floor has 2 bedrooms with 1 queen bed and 1 full bed and a full bath. The third floor master suite has a queen bed and a full bath. All linens and towels included.
Vivas Guesthouse can be rented by the room, offering private floors or as a vacation rental.
Schiller Park Suite sleeps up to eight people - The first floor has a modern and open living and kitchen area. The kitchen is fully stocked with a lovely dining table for 4. The second floor has three rooms. Off street parking available for 2 cars. All linens and towels included.
Schiller Park Suites is available as a vacation rental, making this your private residence for your travel needs in Columbus


text:
Your cart is empty!
Active Ingredients
Aluminum Zirconium Tetrachlorohydrex Gly (18.5% W/W).
Inactive Ingredients
Cyclopentasiloxane, PPG 14 Butyl Ether, Stearyl Alcohol, Hydrogenated Castor Oil, PEG 8 Distearate, Talc, Fragrance (Parfum), Zea Mays Corn Starch.
Apply a thin layer to underarms only.
Secret scent expressions ooh la la body splash, lavender - 3 oz
Our Price:$4.54
Old Spice red zone anti-perspirant deodorant invisible solid, Pure sport - 2.6 oz
Our Price:$4.62
TomS Of Maine Natural Deodorant Stick, Calendula - 2.25 Oz
Our Price:$4.26
Dove men care powerful protection deodorant, clean comfort - 3 oz
Our Price:$2.90
Product descriptions and images presented on the site are for representational use only and do not constitute or substitute for medical information from your health care or medical professional. Information on this site is provided for informational purposes only. You should read carefully all on correct product packaging and follow the instructions. If you have or suspect that you have a medical problem, promptly contact your health care provider. Information and statements regarding dietary supplements on this site have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease and may be for commercial. Image shown for reference only. Actual item you recieve may differ from shown.


text:
March 8, 2013: 100 DFL legislators ask State Legislative Auditor to study orchestra's use of public funds.
April 17, 2013: Talks break down as sides differ on details of financial analysis.
April 30, 2013: In a letter to the board, Vänskä says he will quit if Carnegie Hall cancels orchestra concerts set for November.
June 13, 2013: Legislative Auditor report says Orchestra has used state money properly, but may need to return $960,000 in state grants from 2013.
July, 2013: Former Senate Majority Leader George Mitchell agrees to mediate dispute.
July 22, 2013: Management proposes lifting lockout for two month of talks, with musicians taking a 25 percent cut if no agreement is reached; musicians reject offer.
Aug. 16, 2013: Mitchell proposes lifting lockout for four months, with musicians making their pre-lockout pay, but returning to lockout if no deal is reached. Musicians accept; management rejects.
Sept. 3, 2013: Negotiating team chairman Richard Davis says board is resigned to fact that Vänskä may leave if dispute is not settled.
Sept. 11, 2013: Musicians say they have made financial proposal. Board dismisses it as "vague framework."


text:
"Good plans shape good decisions. That's why good planning helps to make elusive dreams come true."
- - Lester R. Bittel, The Nine Master Keys of Management
The Office of Career Planning & Development is here to help students, alumni, and parents with all aspects of the career planning, process including self-assessment, career exploration, career experience and job search or graduate school planning.
Announcements and Reminders:
- "Backpack 2 Briefcase" Workshop series annouced for Fall 2014. Check the College's Event Calendar for times and locations.
- New off-campus internship opportunities have been announced. Visit the Online Internship Bulletin Board for details.
- Monday, Friday: 8:30 a.m.–6:00 p.m.
- Tuesday, Wednesday, Thursday: 8:30 a.m.–7:00 p.m.
Office of Career Planning & Development
Location: Student Union - Suite 301
Phone: 516-876-3067
Fax: 516-876-3027


text:
Call us for a quotation:
0845 519 4727
BF Internet have an easy way to pay your invoices by Direct Debit. This allows you to pay invoices automatically, direct from your bank account.
You can authorise for payments to be taken for:
Once you've authorised payments, we do the work automatically. This saves you time, leaving you free to concentrate on your business rather than boring admin tasks.
If you'd like to start using Direct Debit payments, you can register today in 2 ways:
Interested in using GoCardless to accept Direct Debit payments for your own business? Click here to find out more – www.bfinternet.co.uk/we-love-gocardless
It is no secret that for the majority of ecommerce website owners, generating more traffic and sales is the key to success. Knowing where to start and what to do is not always clear which is why we have decided to create our own practical guide to Ecommerce SEO.
Before you start to think about optimising your website, you need to have a plan. You may already have a good understanding of which keywords/phrases are important (get in touch if you don't) but don't just stop there. Take some time to type those phrases into Google and see who already appears on page one.
Press release, courtesy of Moore & Smalley and Freshfield PR:
When Mark and Lucy Fuller became frustrated with the lack of a suitable system for managing bookings at their South Lakes Hotel, the entrepreneurial couple decided to create their own.
The booking system they designed, in partnership with a web development agency BF Internet, has been so successful at maximising sales and improving efficiency, they have decided to launch a new venture offering the software to other hotels and accommodation providers.
Direct Room Sales has been designed specifically to help smaller independent hotels offer online sales, manage room allocation, and take electronic payments, all within their existing website.
Mark, who owns The Sun Inn at Kirkby Lonsdale with wife Lucy, said: "For smaller hotels, such as those with fewer than 20 bedrooms, there was nothing out there in terms of software that enabled them to manage online reservations in the efficient way that larger hotels do.
"We wanted a system that allowed us not just to sell our rooms online, but to sequence those room sales in a logical order, offer packages and extras, and do things like automatically change room pricing structures for weekends or certain times of the year. A key feature for us was the link into our EPOS to automatically charge the guest room account."
2013 sees an overhaul of our hosting packages, which we've recently updated onto our website. After listening to feedback from our customers the new range includes a wider choice of upgraded and premium shared hosting packages, offering increased server resource, uptime and support for businesses who rely on their website as a key source of income.
When putting together a hosting package, it is the physical rack space that makes up the bulk of the cost, rather than the hardware itself. By upgrading our hardware specifications to allow servers to be shared between 5-10 websites, we're able to offer this new range of competitive commercial packages. Sharing the rack space means enterprise features are available at the fraction of the cost of a dedicated machine, whilst offering comparable performance & uptime levels.
Google Shopping was a service that was originally started back in 2004 and has evolved over the years. Google recently announced that they were planning to begin changing their Google Shopping channel from a free service to a paid one. This is something that has already taken place in the US last year and will be rolled out in the UK throughout 2013.
Read the rest of this entry »
BF Internet, 7 Shoreline Business Park, Sandside, Milnthorpe, Cumbria, LA7 7BF, UK
Tel: 0845 519 4727 - Fax: 015395 64580 - Email:
1996 - 2015 Big Fish Internet Ltd t/a BF Internet


text:
Sale Sharks launches fundraising initiative
Rugby Union premiership team Sale Sharks has launched its Rugby at the Reebok Community Fundraising Initiative, which aims to raise more than £15,000 for community rugby. The initiative is available for schools, clubs and voluntary organisations purchasing more than 20 tickets for the Aviva Premiership game between Sale Sharks and London Irish at the Reebok Stadium, Bolton on 16 April 2011. The organisation will then receive cash-back for every ticket sold.
Sale Sharks are offering a 'Be the Sharks for a Week' prize for the organisation that sells the most tickets to Rugby at the Reebok. The prize includes training sessions with the first team coaches using state-of-the-art GPS equipment at the Sharks' Carrington training ground and the chance to be part of the behind-the-scenes build-up to an actual Sale Sharks match at Edgeley Park.
Sharks head coach Mike Brewer said: "The whole club is working together to ensure that Rugby at the Reebok is a success and the coaching and playing staff want to play an integral part in this."
Dave Southern, NW RFU regional development manager, said: "I am fully supportive of Rugby at the Reebok and its aim to not only be the premier club rugby event in the North of England, but also to provide an excellent focal point to further grow and develop rugby union and Sale Sharks in the region. This can only be achieved with the support of the whole rugby community."
Margaret Court Arena redevelopment design intent
Security increases at Super Bowl XLIX stadium
ISG named contractor for US$61m York Stadium scheme
Rangers fans protest against board at Ibrox Stadium
Boston 2024 reveals Games plans
Wi-fi can not only provide the backbone for enhanced fan engagement and communication, it also allows a host of commercial opportunities
Click here to read more
US sports fans are more likely to attend games and buy a beer if stadia go green, survey finds
Click here to read more
Tasked with securing the Test match status of Yorkshire County Cricket Club's Headingley Stadium, CEO Mark Arthur discusses the club's recently released £50m (US$84m) masterplan
Click here to read more
Everton FC's Goodison Park has modernised its video security system with the patented multifocal sensor system Panomera from Dallmeier
Click here to read more
Award-winning lighting designer Claudia Paz is passionate about light and finding ways to evoke emotion in those who experience her lighting projects
Click here to read more
We are building a list of leading suppliers covering all aspects of the stadia industry. Want to see your company included? Contact firstname.lastname@example.com for more details.
Do you have an opinion you'd like to share with the stadia community? We'd like to hear your views and opinions on the leading issues shaping the industry. Share your comments by sending up to 500 words to firstname.lastname@example.com
To send us your recruitment advertising or to receive information on placing a banner please email email@example.com


text:
By Bay City News Service
Four homeless people have died in Santa Clara County due to exposure to cold weather conditions, the county medical examiner's office announced today.
Based on results of autopsies, the people succumbed from hypothermia, according to the medical examiner's office.
The names, ages and genders of the individuals are not yet being released.
(Copyright 2013 Bay City News. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed.)


text:
Hi, I've got several bulbs that I've had for several years that are all blooming currently. Splash which is just a bulblet from my mother bulbs that died a few years ago, just 2 flowers and Splash is fragrant too! And then a bulb that I purchased as Royal Velvet but I have my doubts. It is a small flowered extremely dark red (much darker than the picture) with a dusky scape and the tips of the leaves are dark also. The flower is cupped and remains cupped. My mother bulb of Aphrodite succumbed to the NBF about 4 years ago and it took all this time for the three bulblets it produced to finally bloom. A shorter stem and not the usual long pedicels for which I was grateful. Supposedly LaForrest Morton but again I'm not sure. And Samba which reblooms faithfully for me each year. And last but not least my second bulb of Apple Blossom which I think is a different strain from my other which bloomed about 4 months ago and 2 years ago gave me a viable seedpod. This one was very fragrant of course. I have several more older varieties that are opening now too. Thanks for looking, Donna |
This post was edited by dondeldux on Wed, Apr 30, 14 at 10:43
Follow-Up Postings:
Very nice Donna, It seems as though spring arrived later for you this year. How nice that your bloom season is stretched out!! ENJOY!!! K |
- Posted by Jessiann63 8 (My Page) on Wed, Apr 30, 14 at 20:36
All very beautiful Donna. My aphrodite is blooming now also. I haven't heard from my apple blossom this year. I think it's on vacation or something. Louana |
Please Note: Only registered members are able to post messages to this forum. If you are a member, please log in. If you aren't yet a member, join now!
Return to the Amaryllis/Hippeastrum Forum
Information about Posting
- You must be logged in to post a message. Once you are logged in, a posting window will appear at the bottom of the messages. If you are not a member, please register for an account.
- Please review our Rules of Play before posting.
- Posting is a two-step process. Once you have composed your message, you will be taken to the preview page. You will then have a chance to review your post, make changes and upload photos.
- After posting your message, you may need to refresh the forum page in order to see it.
- Before posting copyrighted material, please read about Copyright and Fair Use.
- We have a strict no-advertising policy!
- If you would like to practice posting or uploading photos, please visit our Test forum.
- If you need assistance, please Contact Us and we will be happy to help.
Learn more about in-text links on this page here


text:
Attitude Adjustment
I have before about emotional hygiene and doing the necessary maintenance on feelings as well as your physical body and household. Health reminders tell us to wash our hands frequently to prevent transmittal of diseases. Did you know you can "wash" your mood, too, and give yourself an attitude adjustment whenever you want to?
When I want to have a pleasant time with my husbandRichard, I know it's important to manage my mood and keep myself on an even keel—if anything happens that's disappointing, annoying, upsetting or stressful, I need to re-balance myself and not let it get to me or spoil the day.
Here are some ideas for how to turn your attitude around in the most common mood-disrupting situations:
Disappointment and Expectations
We all have high hopes and rosy pictures of the future when we enter a new situation or relationship. So when life turns out not to be perfect, things don't go the way you hoped, or you find out your partner actually is an imperfect human, just like you, it's disappointing. You may begin by expecting that your partner will always see your point of view, or that as long as you love each other, everything will be OK, but after a while, reality breaks through and you realize your expectations were unrealistic. If you feel you're constantly disappointed and frequently angry, consider that it may be because your expectations don't line up with reality.
No matter how little reality resembles your dreams, there's no need to squabble about it. We all deal with many disappointments in daily life, at home and at work. In most cases, neither you nor your partner would argue with the boss, colleagues at work, or your child's teacher the way you argue with each other. In domestic situations, you can choose your behavior in the same way—you don't have to argue with each other. Instead of bickering like children, use your grownup self-control to pull yourself out of the argument. If you're fighting over silly little things, remember you're having symbolic fights—it's not really about who didn't put the cap on the toothpaste, it's about disappointment, who is right, who has the most power, or who deserves to be loved.
Do's and Don'ts for Handling Disappointment
Okay, so you're disappointed. Your dream has ended in the trashbin. You may want to lay on the floor, kicking your heels, and screaming; or go on a drunken binge, or beat someone up, but if you try it, you'll find you're still disappointed, and all that acting out hasn't fixed anything. Disappointment is a dead-end in your road; so you need to figure out a new direction.
Here are some Do's and Don'ts to help you:
DO put it in perspective: If you're disappointed, it hurts, but your life is not over. Look to your future, and see what you can do to make it better.
DO understand that you had some control, but not total control over this: With an objective look at what went wrong, you can make plans to improve your team effort, your skills, your spirit and then look forward to the next event. Don't blame yourself for the things you couldn't control, but change the things you can.
DON'T give up: You're not a failure unless you quit; so don't quit when you're behind. Instead, get determined to do better.
DO try to learn from the experience: Every disappointment is an opportunity to learn from whatever went wrong. Replay your mental tapes of the event, and figure out how you can do better.


text:
Instructor of English, Interlochen Arts Academy
Instructor of English, The American School in Switzerland
Master of English Education, University of Georgia; Post-Graduate Study, Oxford University, UK; M.A., English, University of Rhode Island; B.A., Liberal Arts and Sciences, University of Illinois; Undergraduate Study, Nottingham Trent University, UK
Karen came to Interlochen in August of 2006 from TASIS England, an American school near London. Karen has also spent many summers teaching English at TASIS, The American School in Switzerland. Since coming to Interlochen, Karen has taught British Literature, English as a Language, Academic Writing, and Creating Children's Literature. She is currently in the process of writing a children's book and two young adult novels, as well as cultivating a Montessori-inspired learning environment for adolescents in her classroom.


text:
Hi everybody, we are building a house and I'm currently working on the kitchen design. I'm terrible at describing things, but it will go refrigerator, built in microwave, range / hood on one wall, and then double oven in the corner, and then around the other wall, sink and dishwasher. We'll have a center island that runs parallel to the refrigerator wall. Does anybody have experience with a double oven built into the corner? The builder says I'll have enough room to stand in front of the oven and open it without bumping into the corner of the island but I was curious if anybody had any experience with this type of layout. Thanks for your help! |
Follow-Up Postings:
Do you have a kitchen design design you can upload? I am no expert but my immediate thoughts would be to move the oven somewhere else. I am imagining taking a heavy dish out and hitting the wall or cabinets next to you. I would also make sure that the corner it is on will not interfere with how you put food in and take it out of your oven. If you usually approach your oven from the left and the wall is on the left the that would obviously be no good. |
My double ovens are in the corner, then a 21 inch countertop, then my range. This set up works nicely for me. I don't have an island to worry about behind me though. |
Here is a picture of the proposed layout. Sorry it's sideways - I can never figure out how to make my iphone shots work head on. Builder is telling me there is enough room to pull down the oven standing directly in front of it. I can't decide if having the island behind me will annoy me regardless! The other option would basically be to switch the double oven and the microwave. I'm worried that it will make the kitchen look heavy on that side with the two biggest appliances next to each other. Maybe not? |
Having ovens in the corner is not generally favored by the design experts on this forum. If you do a google search using the terms "double ovens and gardenweb" you should be able to find lots of previous posts and pictures regarding this topic. Even though they are not favored, I do happen to have my ovens in a corner. I like the way they look and it works fine for us except when I have to wipe off the back wall of the upper Advantium oven. I am a short person with short arms and while I can easily reach the back wall of the lower oven I cant quite do so in the Advantium. I have to snag a taller person to do that for me. I have no trouble getting food in or out of either oven . As you can see in the picture below, I have my ovens recessed into the corner. My cabinets were custom made so I was able to get a perfect fit for angled cabinets on the sides of the oven. The lower doors have a piano hing and they open up wide enough to have good access to the items stored there. If you are able to recess you ovens you would gain a couple more inches of clearance behind you. I didn't have an issue with clearance but liked having the ovens recessed anyway. |
This post was edited by badgergal on Wed, Apr 9, 14 at 20:43
Thanks for sharing your picture and experience badgergal. Your kitchen is beautiful! I searched the forums here for this topic and wasn't finding anything - thanks for the tip about just googling it. I found several posts which have been helpful. |
Alku05 has ovens in a corner. If you have the space, they can work well. Just keep in mind that a 33" oven cabinet takes about 48" on each wall. Check out the link below for pictures of corner ovens (double, MW, etc.) |
Here is a link that might be useful: Thread: Wall ovens in the corner...thoughts?
- Posted by sjhockeyfan (My Page) on Thu, Apr 10, 14 at 11:24
If there's enough aisle space behind you when the oven doors are open, then it will probably be fine. In a previous kitchen we had double ovens next to the fridge and I agree with your thought that it was too heavy/bulky. |
- Posted by ILoveNaptime (My Page) on Thu, Apr 10, 14 at 12:03
Our double ovens are in the corner and our layout is very similar to yours except without the island, with an additional row of cabinets opposite the sink wall, and with the fridge at the end of the sink run. I like the way it functions. It's easy to move things from cooktop to oven and the hot appliances are out of the main traffic thoroughfare, which is important to us because we have little kids running around. |
- Posted by sjhockeyfan (My Page) on Thu, Apr 10, 14 at 12:40
Just looked at the [sideways] picture again - can you move the island back so you have a wider aisle between the cooktop and the island? How wide is that aisle? The issue would be whether it's tight from the corner of the island to the [open] oven door. I would think you'd need at least the width of the oven door plus 24" minimum to be comfortable. I'm not sure what that translates to for the aisle. |
I don't think ovens in the corner are necessarily a bad thing, but I don't know if I would like the obstruction between sink and stove. In the sketch, I think the fridge cab, range hood and oven cabinet look really bulky with relatively small uppers in between. Makig those upper cabinets deeper, and keeping all the heights the same, would help. Are you planning on drawers in your base cabinets? Except for the cooktop, you've shown all doors. Drawers, if sized correctly, are much more efficient. |
- Posted by controlfreakecs (My Page) on Thu, Apr 10, 14 at 14:17
I grew up with stacked oven/mw combo in the corner and an island in similar location to your plan. It was never a problem for us feeling backed into the island when we opened the oven or used the microwave. However, without seeing an overhead plan with actual aisle widths, it is impossible for us, on this forum, to know for certain. Your plan looks pretty good, but I'd want a prep sink on the island, to create a more functional prep space there. I also agree with more drawers, which are much better storage for most things. |
Is there any way you can set the island back and round off the edges? Or maybe change it to a trapezoid/batwing shape? I can see you butting into that sharp corner when taking out a hot and heavy pan, yikes. Also, will y8u have enough clearance on each side of the ovem cabinet so the doors open comfortably? |
- Posted by hollysprings (My Page) on Fri, Apr 11, 14 at 7:09
That's a kitchen that a range would be more suitable choice. The corner ovens eat up a LOT of precious storage space. All of your pots and pans could fit n a lazy susan in that corner, and you'd gain back yards of precious counter space. The ovens interrupt the flow and waste space. |
Thanks for all of your thoughtful comments. We do in fact plan to have drawers in most of the locations in which doors are currently shown. Having worked with slide out shelves in our current kitchen, I agree with you and I can't wait to switch to drawers! I can't tell from our plan the exact distance from the corner of the cabinets to the corner of the island, but I like the idea to somehow round or reshape the edges if we do decide to stay with this layout. I will have to ask the builder for the exact measurement. Hollysprings, would you put a range where the cooktop is now, leave the microwave where it is, and have the corner be counter / cabinets? Thanks again for your comments everybody! I thought I knew what I wanted but now that I have to commit I'm struggling. |
Please Note: Only registered members are able to post messages to this forum. If you are a member, please log in. If you aren't yet a member, join now!
Return to the Kitchens Forum
Information about Posting
- You must be logged in to post a message. Once you are logged in, a posting window will appear at the bottom of the messages. If you are not a member, please register for an account.
- Please review our Rules of Play before posting.
- Posting is a two-step process. Once you have composed your message, you will be taken to the preview page. You will then have a chance to review your post, make changes and upload photos.
- After posting your message, you may need to refresh the forum page in order to see it.
- Before posting copyrighted material, please read about Copyright and Fair Use.
- We have a strict no-advertising policy!
- If you would like to practice posting or uploading photos, please visit our Test forum.
- If you need assistance, please Contact Us and we will be happy to help.
Learn more about in-text links on this page here