text:
Ito, Toyota-Shi
Hideichi Ito, Toyota-Shi JP
Patent application number | Description | Published |
20090267326 | AIRBAG DEVICE - An airbag device includes: a bag body; a linkage member whose an end portion is provided with a latch stopper hole; and a retention device that has a retention member capable of penetrating the latch stopper hole, and that retains the linkage member while the latch stopper hole is penetrated by the retention member, and that discontinues retention of the linkage member as the retention member comes out of the latch stopper hole. The retention member is provided with a slope surface that transforms into a force acts in a direction from a site relatively near to a base end of the retention member to the distal end of the retention member. | 10-29-2009 |
Hiroyoshi Ito, Toyota-Shi JP
Patent application number | Description | Published |
20100102626 | POWER SUPPLY SYSTEM - The power supply system includes a generator, a transformer circuit, and a battery. The generator generates electric power of a first voltage. The transformer circuit boosts the electric power of the first voltage to a second voltage. The battery is connected, via the transformer circuit, to the generator and stores electric power of the second voltage obtained by the boosting by the transformer circuit. At least one of actuators is connected on the generator side of the transformer circuit, so as to be supplied with the electric power of the first voltage. | 04-29-2010 |
20100229017 | IN-VEHICLE POWER SUPPLY APPARATUS - Provided is an in-vehicle power supply apparatus which supplies power to both a high-power load such as an actuator, and the CPU for controlling the high-lower load, and which is capable of preventing reduction in voltage of the CPU even when voltage of the in-vehicle power supply is momentarily reduced due to power consumption of the high-power load, and which include an auxiliary power supply having its capacity reduced so as to enable reduction of the size of the power supply apparatus. The in-vehicle power supply apparatus for supplying a power to both a power load, and a CPU for controlling the power load comprises: a first distribution line for distributing, to the power load, the power supplied from an in-vehicle power supply through a bus; a second distribution line for distributing, to the CPU, the power supplied from the in-vehicle power supply through the bus; an auxiliary power supply, connected to the second distribution line, for supplying the power to the CPU when a voltage is reduced in the bus; and a backward flow prevention section for preventing a charge stored in the auxiliary power supply from flowing into the bus. | 09-09-2010 |
20110128855 | DATA COMMUNICATION NETWORK SYSTEM - A data communication network system which enables an intended unit to determine a start point for a transmission schedule in communication is provided. | 06-02-2011 |
20120228961 | SWITCH DEVICE - There are: a communication sheet that propagates electromagnetic wave; a wireless communication part arranged close to the communication sheet, and stores predetermined information, and wirelessly transmits the predetermined information to the communication sheet; a shield part that shields a radio signal wirelessly transmitted from the wireless communication part; an operation part that enables or disables wireless communication between the communication sheet and the wireless communication part; and a discrimination part that discriminates contents of operation by the operation part based on the predetermined information wirelessly transmitted by the wireless communication part. According to an operation by said operation part to disable the wireless communication between said communication sheet and the wireless communication part, said shield part shields the radio signal from the wireless communication part. | 09-13-2012 |
Ikuo Ito, Toyota-Shi JP
Patent application number | Description | Published |
20080253710 | Rolling bearing device - The rolling bearing includes an inner ring, and an outer ring which is arranged in a concave part which is formed in a fixing member so as not to rotate in a state preloaded in an axial direction toward the inner ring by way of a rolling element, with the fixing member at a bottom surface of the concave part. Moreover, a vibration isolating part formed of a laminated body including a pair of metal layers and a resin layer which is thinner than these metal layers and interposed between them is press clamped to be disposed between an end surface of the outer ring at a preloaded side in the axial direction and the bottom surface of the concave part, in such a manner that a direction of lamination may coincide with the axial direction. | 10-16-2008 |
Katsuyoshi Ito, Toyota-Shi JP
Patent application number | Description | Published |
20080203763 | Vehicle front structure - A vehicle front structure that includes: a fender panel having an outer wall, and an inside end part being bent at a boundary part with a hood panel; an apron upper member that extends in substantially the vehicle longitundinal direction, parallel to the outer wall; a shock-absorbing part that links an inside end of the fender panel and the apron upper member; a cover member, the base end of which is mounted on the inside and that hangs downward as a free end in the substantially downward direction of the vehicle, covers the distal end of the inside and the shock-absorbing part, and extends in substantially the direction transverse direction of the vehicle; and a vehicle side-structure that includes an insertion part formed in substantially the vehicle longitudinal direction near the distal end of the cover member, and into which the cover member may be inserted from above. | 08-28-2008 |
Keita Ito, Toyota-Shi JP
Patent application number | Description | Published |
20130285397 | BUMPER MODULE - A bumper module including a body portion that is positioned between a front bumper cover and a heat exchanger in a vehicle front-and-rear direction and is disposed extending in a vehicle width direction and the vehicle front-and-rear direction; plural longitudinal ribs that are integrally formed on a lower surface of the body portion, extend toward a vehicle lower side, are disposed extending in the vehicle front-and-rear direction, and are lined up at intervals apart from each other in the vehicle width direction; and an air guide rib that is integrally formed on an upper surface of the body portion, extends toward a vehicle upper side, guides cooling air from a vehicle front to the heat exchanger, and whose front end is unaligned in at least one direction of the vehicle width direction and the vehicle front-and-rear direction with respect to front ends of the plural longitudinal ribs. | 10-31-2013 |
Masakazu Ito, Toyota-Shi JP
Patent application number | Description | Published |
20110212497 | METHOD FOR PRODUCTION OF POLYLACTATE USING RECOMBINANT MICROORGANISM - It is an object of the present invention to provide a method for efficiently producing a polylactate via microbial fermentation with the use of a sugar as a starting material. | 09-01-2011 |
20120122165 | RECOMBINANT MICROORGANISM AND METHOD FOR PRODUCING ALIPHATIC POLYESTER WITH THE USE OF THE SAME - This invention provides a recombinant microorganism exhibiting excellent aliphatic polyester productivity and a method for producing an aliphatic polyester with the use of the recombinant microorganism. In this invention, the | 05-17-2012 |
20130045516 | RECOMBINANT MICROORGANISM AND METHOD FOR PRODUCING ALIPHATIC POLYESTER USING THE SAME - Aliphatic polyester productivity is improved for production of aliphatic polyester using a recombinant microorganism. A recombinant microorganism prepared by introducing a gene encoding a protein having activity of converting lactic acid to lactic-acid CoA and a gene encoding a protein having activity of synthesizing polyhydroxyalkanoate using hydroxyacyl CoA as a substrate into a host microorganism is cultured and then aliphatic polyester is recovered from the medium. | 02-21-2013 |
20130157327 | MUTANT POLYHYDROXYALKANOIC ACID SYNTHASE GENE AND METHOD FOR PRODUCING ALIPHATIC POLYESTER USING THE SAME - A substitution mutation that improves polymerization activity of a polyhydroxyalkanoic acid synthase is identified. At least 1 amino acid residue selected from the group consisting of a histidine residue at position 17, a proline residue at position 71, a valine residue at position 131, a methionine residue at position 205, a leucine residue at position 230, and a proline residue at position 239 of a polyhydroxyalkanoic acid synthase derived from | 06-20-2013 |
20130295616 | RECOMBINANT YEAST AND SUBSTANCE PRODUCTION METHOD USING THE SAME - Substance productivity is improved by introducing a metabolic pathway for synthesis of acetyl-CoA or acetic acid from glucose-6-phosphate into yeast. Acetic acid productivity, acetyl-CoA productivity, and productivity of a substance made from acetyl-CoA-derived are improved by attenuating genes involved in the glycolytic system of yeast and introducing a phosphoketolase gene into the yeast. | 11-07-2013 |
Masatoshi Ito, Toyota-Shi JP
Patent application number | Description | Published |
20090110340 | Bearing apparatus for supporting pinion shaft - A pinion shaft is supported in a housing by two tapered roller bearings which are arranged separately from each other in an axial direction, and these two tapered roller bearings are lubricated with lubricating oil in the housing in oil bath lubrication method. A labyrinth forming member in a disc-like shape is disposed with respect to a backward tapered roller bearing out of the two tapered roller bearings, on an end face at a small diameter side of an inner ring thereof in a press-contact manner, so as to be opposed to a rib part which is formed inwardly in a radial direction at a small diameter end of a cage. In this manner, a labyrinth structure for restricting a flow of the lubricating oil is formed between the rib part at the small diameter end side of the cage and the labyrinth forming member. | 04-30-2009 |
Noriaki Ito, Toyota-Shi JP
Patent application number | Description | Published |
20090122788 | Wireless Communication System - A disclosed wireless communication system for realizing a packet switching communication and a circuit switching communication between a mobile station and a fixed station is provided. In this system, said fixed station is configured to, when the packet switching communication is established between said mobile station and said fixed station and the line quality of that packet switching communication deteriorates to a level equal to a predetermined level or less, attempt to establish the circuit switching communication with said mobile station; and said mobile station is configured to, when the packet switching communication is established between said mobile station and said fixed station and said mobile station receives a call from the fixed station on the circuit switching communication, establish the circuit switching communication with the fixed station by responding to that call and then disconnect the packet switching communication with the fixed station. | 05-14-2009 |
20100238052 | EMERGENCY REPORTING APPARATUS - An emergency reporting apparatus including an emergency signal outputting part that outputs an emergency signal when a vehicle is in an emergency status and a logic circuit part that stores an emergency signal output by the emergency signal outputting part with a logic circuit. Furthermore, an emergency reporting apparatus conducts an emergency report with respect to the outside based on the emergency signal output from the emergency signal outputting part. | 09-23-2010 |
Shinya Ito, Toyota-Shi JP
Patent application number | Description | Published |
20120137675 | CONTROL DEVICE FOR INTERNAL COMBUSTION ENGINE WITH SUPERCHARGER - In an internal combustion engine with a variable nozzle vane turbocharger, when the flow rate (VN passage flow rate) of exhaust gas passing through nozzle vanes has reached a spatial resonance region in an exhaust gas passage space between a turbine housing and a catalyst during acceleration, the flow rate is increased so that the spatial resonance region can be quickly passed. When the flow rate (VN passage flow rate) of exhaust gas passing through the nozzle vanes has reached the spatial resonance region during deceleration, the flow rate is decreased so that the spatial resonance region can be quickly passed. Such a control can reduce a period of time during which the frequency of pressure pulsation occurring at the rear ends of the nozzle vanes is amplified in the spatial resonance region, whereby noise caused by the pressure pulsation can be reduced. | 06-07-2012 |
Taira Ito, Toyota-Shi JP
Patent application number | Description | Published |
20140352393 | FORMING DIE APPARATUS AND DIE MEMBER - A forming die apparatus includes a first die on which a die surface is formed and a second die for pressing a workpiece placed on the first die. At least one of the first die and the second die is configured by assembling a plurality of die members. Each die member has a concave side surface facing another die member. | 12-04-2014 |
Takehiro Ito, Toyota-Shi JP
Patent application number | Description | Published |
20140306091 | CASTING MEMBER AND METHOD FOR MANUFACTURING SAME - Disclosed are an inexpensive casting member on which a film with high peel strength is formed, and a method for manufacturing the casting member. A surface-treated mold ( | 10-16-2014 |
Tokiji Ito, Toyota-Shi JP
Patent application number | Description | Published |
20080283007 | ACTUATOR CONTROL APPARATUS AND METHOD - An actuator control apparatus includes: an actuator that changes a state amount of an internal combustion engine; a sensor that detects an actual operation position of the actuator; a controller that controls the actuator to bring the actual operation position of the actuator to a target operation position set based on the operation state of the internal combustion engine; and a diagnosis portion that diagnoses the operation state of the actuator to be normal if the deviation between the target operation position and the actual operation position has been small for a predetermined time period and the amount by which the target operation position has changed in the predetermined time period is equal to or larger than a predetermined value. A method for controlling such an actuator control apparatus is also provided. | 11-20-2008 |
20080289605 | ACTUATOR CONTROL APPARATUS - An actuator control apparatus is provided which has: an actuator provided in an internal combustion engine at a position distant from combustion chambers to change an engine state amount; a sensor that detects the actual operation position of the actuator; a controller that controls the actuator to bring the actual operation position to a target operation position set based on the engine operation state; a diagnosis portion that diagnoses the actuator to be in an abnormal state when the deviation of the actual operation position from the target operation position has been larger than a reference amount for a reference time; and a setting portion that sets, upon the diagnosis by the diagnosis portion, the reference time such that the lower the engine coolant temperature, the longer the reference time, and the lower the ambient temperature, the longer the reference time corresponding to the engine coolant temperature. | 11-27-2008 |
20110174251 | CONTROL DEVICE AND CONTROL METHOD FOR VARIABLE VALVE ACTUATION MECHANISM - A control device includes an engine valve and a variable valve actuation mechanism that is able to change at least one of a valve operating angle and valve lift of the engine valve. When the at least one of the valve operating angle and the valve lift is larger than or equal to a prescribed upper limit, the control device increases an operating speed of the variable valve actuation mechanism as compared with when the at least one of the valve operating angle and the valve lift is smaller than the prescribed upper limit. | 07-21-2011 |
20110178694 | CONTROL DEVICE FOR VARIABLE VALVE ACTUATION SYSTEM - A control device for a variable valve actuation system includes: an engine valve; a variable valve actuation mechanism that variably controls a valve timing of the engine valve and at least one of a valve operating angle and valve lift of the engine valve; a variable setting unit that variably sets a control range, in which at least one of the valve operating angle and the valve lift is controlled by the variable valve actuation mechanism, on the basis of the valve timing; a detecting unit that detects a plurality of valve timings of the engine valve in different modes in such a manner that the control range is changed; and a control range setting unit that variably sets the control range using one of the plurality of detected valve timings. | 07-21-2011 |
20110192364 | VARIABLE VALVE SYSTEM CONTROL APPARATUS - A control apparatus of a variable valve system includes a variable valve timing mechanism that performs variable control of the valve timing of an intake valve of an internal combustion engine, a variable operation angle mechanism that performs variable control of the operation angle of the intake valve, and a control unit that performs drive control of the variable valve timing mechanism and the variable operation angle mechanism. The control unit sets an upper guard for the operation angle according to an actual value of the valve timing, and when a target value of the valve timing is a value on the retard side of a specified determining value, the control unit reinforces the upper guard compared with when the target value of the valve timing is not a value on the retard side of the specified determining value. | 08-11-2011 |
20130133401 | APPARATUS AND METHOD FOR DETECTING ABNORMALITY OF IMBALANCE OF AIR-FUEL RATIOS AMONG CYLINDERS - A detecting apparatus that detects an abnormality of imbalance of air-fuel ratios among cylinders of a multi-cylinder internal combustion engine, which is equipped with a variable working angle mechanism of an intake valve, the detecting apparatus includes an abnormality detection portion that detects a parameter regarding rotational fluctuations of each of the cylinders and detects whether or not there is an abnormality of imbalance of air-fuel ratios among the cylinders. The abnormality detection portion refrains from determining that the air-fuel ratios are normal when the working angle at the time of detection of the parameter is within a predetermined large working angle range, and determines that the air-fuel ratios are normal when the working angle at the time of detection of the parameter is within a predetermined small working angle range that is on a small working angle side with respect to the large working angle range. | 05-30-2013 |
20130192548 | METHOD AND APPARATUS FOR CONTROLLING A VARIABLE VALVE SYSTEM - A variable valve timing apparatus for an internal combustion engine, includes an actuator ( | 08-01-2013 |
20140290219 | CONTROL DEVICE OF INTERNAL COMBUSTION ENGINE - A control device of an internal combustion engine according to the present invention has units configured to inject fuel at a first predetermined ratio from first and second fuel injection valves which are provided in each of cylinders to calculate a first value indicating a degree of variation in air-fuel ratios between the cylinders based on a output of the engine, and inject fuel at a second predetermined ratio therefrom to calculate a second value in the same manner. Furthermore, the control device has a unit configured to select one mode from modes relating to abnormality in the first fuel injection valve or the second fuel injection valve on the basis of the first and second values, and calculate a value indicating the degree of the variation in the air-fuel ratios between the cylinders, thereby calculating a fuel amount of the basis of them. | 10-02-2014 |
20140290348 | ABNORMALITY DETECTING DEVICE OF INTERNAL COMBUSTION ENGINE - An abnormality detecting device of an internal combustion engine according to the present invention includes a sensor nick abnormality detecting unit configured to detect a nick abnormality in a detecting element of a downstream side sensor which is provided in a downstream side of an exhaust gas purifying catalyst in an exhaust passage and generates an output corresponding to an oxygen concentration in exhaust gas, on the basis of a matter that a distribution of an output of the downstream side sensor is biased to an area in which the air-fuel ratio is leaner than a theoretical air-fuel ratio, and an inhibiting unit configured to inhibit detection of the nick abnormality of the detecting element by the sensor nick abnormality detecting unit in the case that an intake air amount exceeds a predetermined amount. | 10-02-2014 |
Toshikazu Ito, Toyota-Shi JP
Patent application number | Description | Published |
20100045018 | TANK MOUNTING MECHANISM AND VEHICLE EQUIPPED WITH TANK - A tank mounting technique of the invention effectively responds to a variation in size of a high-pressure tank T in its longitudinal direction and allows positioning of the high-pressure tank T around its longitudinal axis. A tank receiving recess | 02-25-2010 |


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Haptix is a sensor that enables multitouch on any surface, such as a screen, keyboard, or table. The creators are competing in MAKE's 2013 Hardware Innovation Workshop, set for May 14-15 to compete in the "pitches with prototypes" contest.
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Publications (9)51.08 Total impact
- [Show abstract] [Hide abstract]
ABSTRACT: In vivo models of human tumor vasculature are essential for the study of tumor angiogenesis and validation of therapeutic targets. To date, however, few standardized animal models of human tumor angiogenesis have been characterized. It was recently shown that human renal cell and prostate carcinoma primary xenografts, established from biopsy specimens, contained vessels lined mainly by human endothelial cells 1 month after implantation in immunodeficient mice. We selected colorectal cancer (CRC) as a primary xenograft model and studied the response of the vascular compartment to the new microenvironment during the same lapse of time. Immunohistochemical analysis of the origin of endothelial cells demonstrated that, in contrast to the mentioned study, human endothelial cells were rapidly substituted by their murine counterparts (nearly 50% by day 10 after implantation). Apoptotic human endothelial cells could not be detected 10 days after implantation, suggesting that apoptosis is not the mechanism underlying their replacement. Interestingly, host endothelial cells were found to colocalize with human laminin, suggesting a colonization of human vascular basement membranes after human endothelial cell disappearance. To rule out that the differences observed between the fate of human vasculature in the CRC model and those previously reported were because of methodological aspects, we established renal cell carcinoma (RCC) primary xenografts using the same protocol. In clear contrast with CRC xenografts, vasculature within RCC xenografts was mostly of human origin 35 days after implantation. These results support the notion of angiogenic heterogeneity in malignant neoplasms. Elucidation of the molecular mechanisms that determine persistence or disappearance of human endothelial cells in different tumor contexts can help to shed light on the intimate regulation of the angiogenic process.Laboratory Investigation 12/2008; 89(1):91-7. · 3.96 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Hereditary non-polyposis colorectal cancer (HNPCC) represents 1-3% of all colorectal cancers. HNPCC is caused by a constitutional defect in a mismatch repair (MMR) gene, most commonly affecting the genes MLH1, MSH2 and MSH6. The MMR defect results in an increased cancer risk, with the greatest lifetime risk for colorectal cancer and other cancers associated to HNPCC. The HNPCC-associated tumor phenotype is generally characterized by microsatellite instability (MSI) and immunohistochemical loss of expression of the affected MMR protein. The aim of this study was to determine the sensitivity of IHC for MLH1, MSH2 and MSH6, and MSI analysis in tumors from known MMR gene mutation carriers. Fifty-eight paired normal and tumor samples from HNPCC families enrolled in our high-risk colorectal cancer registry were studied for the presence of germline mutations in MLH1, MSH2 and MSH6 by DGGE and direct sequencing. MSI analysis and immunostaining for MLH1, MSH2 and MSH6 were evaluated. Of the 28 patients with a real pathogenic mutation, loss of immunohistochemical expression for at least 1 of these MMR proteins was found, and all except 1 have MSI-H. Sensitivity by MSI analysis was 96%. IHC analysis had a sensitivity of 100% in detecting MMR deficiency in carriers of a pathogenic MMR mutation, and can be used to predict which gene is expected to harbor the mutation for MLH1, MSH2 and MSH6. This study suggests that both analyses are useful for selecting high-risk patients because most MLH1, MSH2 and MSH6 gene carriers will be detected by this 2-step approach. This practical method should have immediate application in the clinical work of patients with inherited colorectal cancer syndromes.Oncology Reports 10/2004; 12(3):621-9. · 2.19 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Topoisomerase (Topo) II isoenzymes are the targets for drugs, such as epidophyllotoxins and doxorubicin. The aim of this study was to determine whether the expression of Topo IIalpha and Ki67 in advanced Hodgkin's disease (HD) played a role as a prognostic factor or predictor of response to treatment. Forty-two patients who were homogeneously treated and had a long-term follow-up were selected for the study. Immunohistochemistry of paraffin-embedded tissue sections was performed. The effect of patient and tumor characteristics on failure-free survival (FFS) and overall survival were evaluated in a univariate analysis using the Cox proportional hazards model. The Cox model was also implemented in a multivariate analysis using stepwise selection. Positive nuclear staining for Topo IIalpha in Reed-Stemberg or Reed-Stemberg variant cells was seen in 90% of HD cases, and coexpression of Ki67 and Topo IIalpha in 79%. No significant difference in the percentage of Topo IIalpha-positive cells was detected among histological HD subtypes. In the univariate analysis for FFS, the male gender, high lactate dehydrogenase, and Topo IIalpha < 30% were associated with more relapses. In the multivariate analysis for FFS, only Topo IIalpha < 30% was statistically associated with shorter FFS, with relative risk of 3 (95% confidence interval, 1.26-7.15; P = 0.013). In uni- and multivariate analyses for overall survival, only Topo IIalpha was associated with shorter survival. Topo IIalpha expression could be useful in advanced HD to identify patients with a higher risk of relapse and lesser overall survival. It is of potential utility in the design of specific treatments.Clinical Cancer Research 05/2003; 9(4):1406-11. · 8.19 Impact Factor -
Article: Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
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ABSTRACT: The development of new therapeutic strategies is essential for the management of gliomas, one of the most malignant forms of cancer. We have shown previously that the growth of the rat glioma C6 cell line is inhibited by psychoactive cannabinoids (I. Galve-Roperh et al., Nat. Med., 6: 313-319, 2000). These compounds act on the brain and some other organs through the widely expressed CB(1) receptor. By contrast, the other cannabinoid receptor subtype, the CB(2) receptor, shows a much more restricted distribution and is absent from normal brain. Here we show that local administration of the selective CB(2) agonist JWH-133 at 50 microg/day to Rag-2(-/-) mice induced a considerable regression of malignant tumors generated by inoculation of C6 glioma cells. The selective involvement of the CB(2) receptor in this action was evidenced by: (a) the prevention by the CB(2) antagonist SR144528 but not the CB(1) antagonist SR141716; (b) the down-regulation of the CB(2) receptor but not the CB(1) receptor in the tumors; and (c) the absence of typical CB(1)-mediated psychotropic side effects. Cannabinoid receptor expression was subsequently examined in biopsies from human astrocytomas. A full 70% (26 of 37) of the human astrocytomas analyzed expressed significant levels of cannabinoid receptors. Of interest, the extent of CB(2) receptor expression was directly related with tumor malignancy. In addition, the growth of grade IV human astrocytoma cells in Rag-2(-/-) mice was completely blocked by JWH-133 administration at 50 microg/day. Experiments carried out with C6 glioma cells in culture evidenced the internalization of the CB(2) but not the CB(1) receptor upon JWH-133 challenge and showed that selective activation of the CB(2) receptor signaled apoptosis via enhanced ceramide synthesis de novo. These results support a therapeutic approach for the treatment of malignant gliomas devoid of psychotropic side effects.Cancer Research 09/2001; 61(15):5784-9. · 9.28 Impact Factor -
Article: Analysis of genetic and epigenetic processes that influence p14ARF expression in breast cancer.
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ABSTRACT: The INK4a/ARF locus encodes two unrelated cell cycle-regulatory proteins that both function in tumor suppression, p16INK4a and p14ARF. In human tumors including breast cancer, alterations affecting selectively p14ARF have been poorly analysed. We have performed a comprehensive analysis of the inactivation mechanisms (mutation, homozygous and hemizygous deletion, and promoter hypermethylation) in a large series of 100 primary breast carcinomas. RT-PCR showed expression variable of the p14ARF transcript, with 17% demonstrating overexpression and 26% demonstrating decreased expression. No detectable alterations were observed in the majority of cases with overexpressed p14ARF mRNA, but 77% of tumors with decreased expression presented at least one of these genetic/epigenetic alterations. Nevertheless, a statistically significant correlation was observed between decreased p14ARF expression and several poor prognostic parameters.Oncogene 08/2001; 20(33):4586-90. · 8.56 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: To explore the induction of chemotherapy (CT) DNA damage and its correlation with tumor response and patient survival, we undertook the present study in 20 small cell lung cancer (SCLC) patients. All patients underwent the same treatment based on CT courses of carboplatin and etoposide. Blood samples were taken before and immediately after CT and every 12 weeks during follow-up. Nuclear DNA damage was determined through the variations in three mitochondrial pseudogene mutations in DNA of peripheral blood mononuclear cells. They were detected by mutation-specific PCR and assessed by a semiquantitative method. The relative level of mutation rose after chemotherapy in all cases. Among the 11 patients (55%) with higher relative levels of mutations, 9 (82%) of them achieved a complete response. In contrast, of the 9 patients (45%) with lower relative levels of mutations, only 2 (18%) achieved a complete response, displaying a statistically significant difference (P=0.02). The overall survival for patients with marked genomic damage was 18 months (range 10-24), and for patients with low degree of DNA damage, it was 12 months (range 5-15) (P=0.002). Genomic damage detected after chemotherapy treatment correlates positively with tumor response and patient survival.Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 12/2000; 456(1-2):65-71. · 4.44 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Hypermethylation of exon 1 of p16INK4a was examined in tumour and plasma DNA of a series of breast cancer patients. De novo methylation was observed in the tumours of eight patients (23%), and in plasma DNA in five (14%) of these eight patients. Our data show that de novo methylation of exon 1 of p16INK4a can be demonstrated in plasma DNA of breast cancer patients, a fact that provides additional evidence of the tumour-related origin of free plasma DNA in cancer patients.British Journal of Cancer 07/1999; 80(8):1262-4. · 4.82 Impact Factor - European Journal of Cancer 09/1998; 34. · 4.82 Impact Factor
- European Journal of Cancer 02/1998; 34. · 4.82 Impact Factor
Publication Stats
282 | Citations | |
51.08 | Total Impact Points | |
Top Journals
Hospital Universitario Puerta de Hierro-Majadahonda
Madrid, Spain


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Tue, 03 Feb 2015 / Drum & Bass Special - Krakota Krakota, Photon, Nuera, Chemical Case, Kindred..2 Attending
Fri, 8 Nov 20132 commentsHeidi billed for WearejunkThe Jackathon DJ will help ring in the new year for the Southampton party.
Tue, 14 Jun 201114 commentsKerri Chandler sets sail with Circo LocoThe US house legend will appear at Junk club with Lee Curtiss this weekend.
Wed, 25 Aug 2010Post a commentBank Holiday round-up: South & EastWe take a look at what's going on in Brighton, Maidstone and Southampton this Bank Holiday.
Tue, 8 Jun 2010Post a commentSimian Mobile Disco celebrate Five years of JunkThe techno-electro duo will play the Southampton club's fifth birthday next weekend.
Sat, 7 Feb 2015108 AttendingMoody Disco 4th Birthday: Richy Ahmed, Clive Henry & Russ YallopThe Brighton Coalition


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For patients
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What we offer
Postgraduate medical education
Education and training
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Work with us
Continuing professional development
At the Whittington we are committed to Continuing Professional Development. We believe that life long learning helps to meet the requirements of those people needing the NHS.
At the Whittington we provide continuing professional development that is:
Purposeful and patient centred
Targeted at identified educational need
Educationally effective
Part of a wider organisational development plan in support of local and national service objectives
Focused on the development needs of clinical teams, across traditional professional and service boundaries
Designed to build on previous knowledge, skills and experience
Designed to enhance the skills of interpreting and applying knowledge based on research and development.
Continuing professional development is available for all practitioners and the modes of delivery are variable and flexible. This allows you to develop your individual career pathway with support from the Trust.
Specialist Roles To Support
The Trust has a number of roles with a specific remit for education. An Assistant Director of Education oversees the provision of education to all staff, with the exception of doctors in training who are supported by the Director of Postgraduate Medical Education. There are a number of practice development nurses and midwives, whose role is to contribute to the development of skills amongst nurses and midwives in clinical areas. For postgraduate medical education there is also a network of highly experienced educational supervisors.
We'll support you in meeting your PREP requirements
To be part of the Continuing Professional Development Framework and maintain NMC Registration, all registered Nurses and Midwives are required to undertake a minimum of 35 hours of learning activity during each three-year registration period, irrespective of the number of qualifications they possess. When practitioners do not comply with the above CPD standard and the maintenance of a personal professional profile, they will be considered to have allowed their own registration to lapse. We encourage our staff at the Whittington to record all learning in a personal professional portfolio provided by the Trust. This enables staff to demonstrate to the NMC all learning activities that have been undertaken.
In-Service Clinical Education and Training Programme
Personal development planning is actively encouraged by the Trust and once a plan has been agreed staff may commence on an education programme. We provide development programmes for all our staff nurses and sisters along with a range of individual clinically focused study days such as Advanced life support, intravenous Cannulation, Stroke management, discharge planning, to name but a few. The list is endless. These study days meet individual's development needs and importantly provide resources to deliver high standards of patient care. Our human resources department also runs a range of study days from interviewing skills to assertiveness training.
Links with Higher Education Institutions (HEIs)
We have close links with two major Higher Education Institutions (HEIs), Middlesex University and University College London. Middlesex University provide pre and post registration-training opportunities for nurses and midwives, along with post registration opportunities. The post registration opportunities are wide and varied, there is access to a full clinical course e.g. intensive care or A&E nursing. There may be times when it is not necessary for you to undertake a full clinical course. However, a specific module or modules may be pertinent to your practice. In this situation, you could undertake the module(s) and on successful completion be credited with the relevant number of academic credits.
And of course there are other ways to further your development, which we encourage.
Attendance At Conferences
A large number of conferences are regularly organised across a wide variety of venues throughout the country. Conferences serve several purposes; they give you the opportunity to:
Keep up to date with ongoing developments within your own specialist area.
Share knowledge and new skills
Network with colleagues from similar backgrounds.
At the Whittington we advertise widely the wide range of forthcoming conferences.
Informal Learning
This can be extremely helpful and informative and take many forms e.g. reading books, relevant journals, observing others at work and attending meetings. All clinical areas have access to the internet and all members of staff have access to the local Trust and university library resources.
Learning Within The Workplace
This can be done through a variety of methods including, clinical supervision, Mentorship, critical incident analysis and peer review, to name but a few.


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Melissa Etheridge News
LYRIC VIDEO PREMIERE: Melissa Etheridge 'Uprising of Love'
100% of ALL PROCEEDS from the single are going toward the Russia Freedom Fund to assist LGBT activists in Russia
Similar Artist News
Share Your Thoughts On Kelly Clarkson's 'Piece by Piece' Lyrics
The pop star's seventh studio album drops March 3rd! She's got a cool new lyric feature for her fans in the meantime
It Takes Two! These Duos Will Blow You Away At The GRAMMYs
Check out the list of 2015 GRAMMY pairings who'll take the stage together on Feb. 8th
Is This The Most Random GRAMMYs Performance Lineup Ever?
The 2015 awards show will host a bevy of totally different music genres — not to mention generations
Madonna's Leaked 'Rebel Heart' Tracks: Ranked
How do Madge's latest crop of songs from her upcoming LP stack up? We analyzed 'em track by track
Get To Know The 'WILD' Soundtrack With These Exclusive Lyric Cards
Seriously, this movie's getting some major Oscar buzz: see the most pivotal songs from the film's soundtrack in lyric…
Our Pop Xmas Playlist Might Make You Drop Your Shopping List & Dance
Don't say we didn't warn you. Here's our ultimate Christmas pop playlist on Spotify and YouTube!
Watch Band Aid 30's "Do They Know It's Christmas?" and Help Stop Ebola
Can you spot all the stars in the latest Band Aid roundup? Listen to the reworked song and help fight the Ebola virus
Find Out The 20 Most Catchy Songs Of All Time
Can you guess which ones made the list?
Watch BBC Music's Star-Studded "God Only Knows" Cover
Pharrell, Lorde, One Direction, Florence Welch, Chris Martin & more take on the Beach Boys' classic hit
Watch Foo Fighters & Heart Play 'Kick It Out' on Letterman
Night two of the Foo Fighters' week-long Letterman residency...
WATCH Renowned Songwriter Dan Wilson Share His Secret to a Great Collaboration
Dan explains what goes into a great collaboration using The Dixie Chicks' "Not Ready To Make Nice" as an example...
Fleetwood Mac Returns! Co-Founder Mick Fleetwood Dishes On Reunion Tour
Tune in to CBS Sunday Morning on Sept. 28th to get the details on the legendary rock band's comeback
Counting Crows To Perform New Song 'Scarecrow' on CBS This Morning
Plus an exclusive interview...
Sarah McLachlan Admits She Was "Musically Nowhere" To CBS Sunday Morning
Even best-selling singer/songwriters go through writer's block. Find out what was holding Sarah back on her new album
Play These 8 Reggae Jams At Your Next Beach Outing
What is it about reggae that makes us think of sunshine? Enjoy these tracks on your next sunny day on the sand.
Madonna Shares Lyrics to New Song "Messiah" On Instagram
Take a look at a snippet of new lyrics from the legendary pop star.
Celebrate Canada Day With 15 Songs By Canadian Artists
It's Canada Day on July 1st! Celebrate your Canuck status with these 15 songs...
WATCH Tori Amos' "Trouble's Lament" Lyric Video
The lead single from the singer/songwriter's new album 'Unrepentant Geraldines' gets the lyric video treatment!
The 10 Best Songs From Pop Star Mamas
Just in time for Mother's Day, these 10 pop stars know a thing or two about motherhood, especially in their lyrics!
15 Earth-Friendly Anthems For Earth Day 2014
Happy Earth Day! Let Michael Jackson, Madonna, Marvin Gaye & more show their love of Planet Earth in our green playlist.
15 Easter-Ready Tracks To Kick Off Your Long Weekend
Hoppy Easter! Celebrate with our Spotify playlist on your Easter long weekend.
All The Highlights From The 49th ACM Awards
Miranda Lambert was this years' big winner: see who strutted their stuff on the ACMs stage in Vegas!
International Women's Day: 15 Girl Power Tracks
We're celebrating International Women's Day by blasting these 15 tunes about being a girl!
All The Musical Moments at the 2014 Oscars
The 86th annual Academy Awards just went down -- who were the big music winners / performers?
10 Single & Proud Songs for Valentine's Day
These pop stars don't need a man (or woman!) this V-Day!
Paramore, Little Mix, and J.Lo Top Our Trending Tuesday List
These 10 #TrendingTuesday songs are on our radar this week!
The Best Songs From Super Bowl Halftime Performers
Go from present (Bruno Mars) to past (No Doubt) performers in our Spotify playlist for the 2014 Super Bowl.
See What Songs Miley Cyrus Performed On MTV's 'Unplugged'
The country cutie went Western (and brought Madonna on board) for her unplugged set!
Our Favorite Disney Movie Songs Sung By Popstars
Inspired by Lana Del Rey's "Once Upon A Dream" rendition, we're counting down the best Disney songs by some of pop's…
GRAMMYs Recap: All The Winners And Performances
The 56th annual GRAMMY awards went down last night, and we're highlighting the best moments from the show!
15 Songs From 2013's Best Movies
Just in time for the Oscar nominations, we've put together a movie-magic playlist just for you.
All The 'Best Original Song' Nominees at the 2014 Oscars
Check out who's up for an Oscar thanks to their songwriting skills!
The 5 Best Lyric Videos of 2013
This year was jam-packed with some of the best lyric vids we've ever seen...
Daniel Kim's "Pop Danthology" Mashup Features 2013's Biggest Songs
Check out this amazing 6-minute mashup of 2013's smash hits!
Let Drake, Eminem and Celine Dion Sing Your Thanksgiving Playlist
Feeling thankful for turkey this Thanksgiving? Give our Spotify playlist a spin!
U2's New Song "Ordinary Love" Gets An Extraordinary Lyric Video
The band's first new track in four years comes with a gorgeous new lyric clip.
Kelly Clarkson's Pregnant! 3 Lyrics That Celebrate Her New Chapter
These 3 KC lyrics are perfect for her to dedicate to her baby-to-be.
Kelly Clarkson Reveals Lyrics to Christmas Single "Underneath the Tree"
Get to know the words to the diva's holiday pop single!
15 Superstitious Songs For Friday The 13th
Spooked out by Friday The 13th? This playlist might not be for you...


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Volvo P1800S 1969 in very good condition Beautiful, in very good condition 1969 Volvo P1800S. Great red paint, interior black with red carpet. Beautiful old... More
1973 Volvo 1800ES Sport WagonStation wagonAuto transmissionLots of new partsRuns goodVery little rustNew fuel pumpNew hosesFactory airGreat investment125000 milesV4Vehicle is located in Charlotte... More
Volvo 1800ES 1972 very good condition Beautiful, very good maintained 1972 Volvo 1800ES. Red paint, electric sunroof. Car runs and drives superb, great paint, beautiful... More
Volvo P1800S 1966 projectcar 1966 Volvo P1800S for restoration including welding to be done. Engine turns by hand. Car has Belgium title. Easy to register in... More
Volvo P1800E 1970 in good condition This is a very nice, in good condition Volvo P1800E from 1970. Car has automatic gearbox, airconditioning fonctions fine.... More
1965 Volvo 1800S Coupe Just arrived at SportsCar LA, this Volvo was delivered new in California and has been a Hollywood car for... More
We are very excited to present this 1972 Volvo P1800E Coupe! Finished in its original shade of 110 – Cypress Green over 351-811 –... More
1982 Volvo 245 Turbo Light overall restoration about 3 years old with paint. Light metallic blue with blue velour interior. Manual transmission, power windows, power... More
1971 Volvo P1800E that is a good candidate for restoration. The car is in silver with a black interior and it has automatic transmission... More
1966 Volvo P1800S that is a good candidate for restoration. The car is in red with a black interior. It has been standing for... More
This 1966 Volvo 122 S Coupe is a very cool and early example of these great cars, this one is a US version that is rusn and drives... More
1968 Volvo P1800 '68 Volvo P1800, maroon with black interior, sitting for many years, excellent original car to restore. For $6,950 USD. If you have any additional... More
VOLVO: 1972 1800 ES, very nice, long time New Mexico car, well maintained, recent respray in original color, tan leather interior, recent reseal of... More
VOLVO: 1968 122S, good condition, some minor rust, original owner, 169,000 miles, runs well, $7,500, negotiable. 914-329-3718, NY.... More
VOLVO: 1986 740 turbo wagon, very low hours on rebuilt engine, accident-free, sound body, California auto, not running, maroon, needs some TLC, value in... More


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Dr. David W. Smith, MD
Cardiovascular Disease, Southern Medical Group
- 1300 Medical Dr
Tallahassee, FL 32308 - 1 Office Location
- (850) 216-0100
Dr. David W. Smith graduated from the University of Florida College of Medicine at Gainesville in 1983. He works in Tallahassee, FL and specializes in Cardiovascular Disease. Dr. Smith is affiliated with Tallahassee Memorial Healthcare.
Gender: Male
Years in Practice: 32 Years
Languages Spoken: English
Medical School: University of Florida College of Medicine at Gainesville
Graduation Date: 1983
Hospital Affiliations: Tallahassee Memorial Healthcare
Specialties: Cardiovascular Disease


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Wii Bowling for Adults - LSC-CyFair
Ten Pin Challenge Events
The Ultimate Wii Sporting Competition Returns February 23!
New for 2015!
Practice and Tournament All on One Day!
February 23 at 9:00 a.m.-10:00 a.m.
February 23 at 10:00 a.m.-12:00 p.m.
Free. No registration is required. Open to anyone at least 18 years old. Sessions are held in LRNC 131. Prizes are generously donated by the Lone Star College-CyFair Branch Friends of the Library!
Contact Tracy Williams (phone 281-290-3243 or e-mail firstname.lastname@example.com)
Contact the LSC-CyFair Library: chat | e-mail | 281.290.3214 or 281.290.3219
Maintained by: T. Williams-Reference Librarian


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2 million in grants fuel Gothenburg development in 2012
A full plate could describe the past year in Gothenburg with everything from grants for development and improvements to medical facility construction and a lingering drought.
Development of a new industrial site, in southeast Gothenburg, was buoyed by a $500,000 grant from the Nebraska Department of Economic Development plus a $300,000 rural development grant from the United States Department of Agriculture.The grants will help pay for the estimated $1.3 million project that will pave, install sewer and water and make other improvements to part of the 350-acre site .
Close on the heels of the awarding of those grants was $1.2 million in grants, with $308,301 still pending, from various agencies for the rehabilitation of Lake Helen.
Draining, dredging and shrinking the lake, along with other improvements, is estimated to cost $1.5 million and is expected to help clean and rid the lake of geese.
At the beginning of 2012, the town celebrated the opening of $2.9 million doctor's clinic that adjoins Gothenburg Memorial Hospital.
The 18,000 square-foot clinic took about nine months to build and was expected to alleviate cramped conditions in the building where Gothenburg Family Practice was formerly located.
For ag producers and ag-related businesses, high commodity prices were offset by a year of little or no rain with scorched pastures and burned up dry-land corn.
Much more precipitation, than what the area received in last week's snowstorm, is needed to improve soil conditions for spring planting and cattle grazing.
Latest Headlines
- Two Swedes in winner's circle
- Cozad contains Swedes in rivalry game
- Swedes fail to sweep Chase County
- New county leadership
- Eagles fly high after 1-1 weekend
- Gasoline prices catching up with drop in crude oil prices
- Lecturer says genetically engineered animals could ease world hunger
- Peterson: Movie-making in Chicago friendlier atmosphere than in LA, NYC


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Speed through town on Schwinn's simple and stylish Racer. This urban bike boasts a nimble steel frame and fork with easy-rolling 700c aluminum wheels for an efficient, smooth ride you'll love. You also get a flat handlebar for excellent control as well as a rear coaster brake and front hand brake… [more]
From its retro-style frame to its fixie attitude, Schwinn's Cutter screams sleek simplicity. This city rig is made of steel for an efficient ride plus strength and durability so you'll enjoy this beauty for years to come. The flat bar and aluminum stem provide ample control, while the brakes offer… [more]
Civia's Twin City Step Over 1-speed is all about simplicity with clean aesthetics and low maintenance components. Its reinforced steel frame and fork features an upright riding position for comfort and easy viewing of the road ahead. A chainguard keeps your pants clean, and the single speed gearing… [more]


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Spanish bullfighter Jose Tomas on September 25, 2011
Final fight: Jose Tomas in action on the final day of bullfighting at Barcelona's Monumental arena.
If you have inside knowledge of a topic in the news, contact the ABC.
This service may include material from Agence France-Presse (AFP), APTN, Reuters, AAP, CNN and the BBC World Service which is copyright and cannot be reproduced.
AEDT = Australian Eastern Daylight Savings Time which is 11 hours ahead of UTC (Greenwich Mean Time)


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How to Do Your Hair Like Anna and Elsa From Frozen
Do You Wanna Build an Updo? 5 Cool Hairstyles Inspired by Frozen
What's Your Reaction?
Thanks for your reaction
Don't forget to share this with your friends!
Do You Wanna Build an Updo? 5 Cool Hairstyles Inspired by Frozen
Children, mine included, have been singing the songs from Disney's Frozen for months now, but my daughter went a step above crooning the tunes over and over again. She wanted their updos. And badly. She told me she wished her locks would look "exactly how the real Anna and Elsa's mommy does theirs." So, as any good mom (who's bad at hair) would do, I scoured the web and found a few easy enough tutorials that are sure to have your Arendalle-dreaming-lady looking like the princess you already know she is.
Source: Instagram user kappen_erica
Hair Tutorials
Link Love
- Shakira welcomes a second son — People Moms & Babies
- Can you love your child too much? — BabyCenter Blog
- The skills your mom never taught you — Real Simple
- The 9 mom "friends" you don't need — HuffPost Parents
Latest Moms


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Spacious, plenty of tables. Prompt service and good coffee. Small selection of baked goods. Easy parking. Free WiFi. What more could you want?
If you own or manage Durango Joe's Coffee on College Dr., register now for free tools to enhance your listing, attract new reviews, and respond to reviewers.


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National Security
Power surges with no clear fix led NSA to delay the opening of a major data center in Utah. (Stock image)
The opening of the National Security Agency's $1.5 billion Utah Data Center has been delayed for a year, according to a Wall Street Journal report citing project documents and current and former officials. The 1 million square foot data center, rumored to be the largest on Earth -- though its exact storage capacity is classified -- was most recently scheduled to open in the fall of 2013.
Instead, a series of 10 electrical surges over the past 13 months has curtailed the NSA's computing effort at the Bluffdale, Utah, facility south of Salt Lake City. The cause of the meltdowns remains unclear, and none of the proposed fixes are guaranteed to solve it, an unnamed Utah official told the Wall Street Journal.
The surges have added to the Utah Data Center's price tag, causing several hundred thousand dollars' worth of damage to equipment, and likely adds to the NSA's internal list of recent problems that include top-secret surveillance documents leaked by former contractor Edward Snowden.
Ironically, the Utah Data Center was set to open three months after Snowden disclosed its likely contents: intercepted phone records, e-mails, Internet traffic and a slew of satellite and other telecommunications data.
About the Author
Frank Konkel is a former staff writer for FCW.
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FCW is proud to support this Feb. 9 event to help the soldiers of Operation Iraqi Freedom and Operation Enduring Freedom transition to civilian careers.
Click here to learn more
FCW investigated efforts by the departments of Defense and Veterans Affairs to improve a joint data repository on military and veteran suicides. Something as impersonal and mundane as incomplete datasets could be exacerbating a national tragedy.
Despite delays, the program is at a critical point for determining the ultimate impact of cloud technology in the government space.
In an interview with FCW, the Department of Veterans Affairs' chief technology officer talks about overhauling the digital experience for VA customers.
The National Information Exchange Model's usefulness extends far beyond its origins in justice and law enforcement.
ACT-IAC'S Rick Holgate and Dan Chenok look ahead to what's next for federal IT in 2015.
A bill that will allow DHS to hire cybersecurity professionals faster and pay them more now heads to the president for his signature.
How NASA and other agencies are using contests to bring better ideas into acquisition.
ONC will focus more on data interoperability and the use of health IT to improve patient outcomes.
A new report from the DOD CIO offers soup-to-nuts guidance on security for commercial cloud providers and Defense Department customers.


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National Maple Syrup Festival
March 5 - 8, 2015 / Brown County, Indiana
About The Festival
The Dutch Oven Diva
Sweet Victory Challenge
Dinner Series
Christine Tailer:
Thu., March 5 @ 6 p.m.
Mike Farrell:
Fri., March 6 @ 6 p.m.
Breakfast Series
Visit Brown County!
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Cool U.S. Maple Headlines
Roy Boswell
Donna Shortt (Making Syrup)
Donna Shortt (Making Syrup in March)
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Pamela C. Newell Painting
Roy Boswell Painting
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Explore Brown County!
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Judge Declares ObamaCare Unconstitutional
A federal judge today struck down U.S. President Barack Obama's controversial ObamaCare law, declaring parts of the health care bill unconstitutional. More specifically, the judge sided with 20 states – including Georgia – in ruling that Obama can't force Americans to buy health insurance if they don't want it.
U.S. District Judge Roger Vinson agreed with the states that the new law violates people's rights by forcing them to buy health insurance by 2014 or face penalties. He went a step further than a previous ruling against the law, declaring the entire thing unconstitutional if the insurance requirement does not hold up.
Attorneys for the administration had argued that the states did not have standing to challenge the law and that the case should be dismissed.
Justice Department spokeswoman Tracy Schmaler said Monday the department strongly disagrees with Vinson's ruling and intends to appeal.
"There is clear and well-established legal precedent that Congress acted within its constitutional authority in passing this law and we are confident that we will ultimately prevail on appeal," she said in a statement.
52 Responses to "Judge Declares ObamaCare Unconstitutional"
Conservative judicial activism..who would have thunk it?
Hell, I don't mind paying more in taxes if it helps others! I SUPPORT MY PRESIDENT!!!
Sandra, calm down.
stunnaz says:
I think Americans need a health care plan like we have here in the UK….your health bills are just so damn expensive , it affects your overall incomes…. everyone should have access to healthcare
I concer. My old boss was British and he got a kick out of our "nightly drug commercials" that run every other minute. Only in America!
concur -
BusyBee, I feel you. I just know alot of people that need health care. I know some dead folks that might have been here now only if they had access to health care.
Bee, not all fit into those categories. Your state probably deals with more aliens than any other. I'm in Chicago, it's not them that in the ER,(too scared to get deported)it's everybody and their momma up in there. Not every sick person needs an ER, they need to be able to go to a doctors office and get preventive care and health education.
We could discuss immigration policy, or lack thereof, all night long.
RealAsh, if I could I would, but I can't so we don't and won't have to worry about that
I'm too busy footing my own!
LA, it was my understanding that you couldn't purchase the "care" across state lines. Is that not that case?
This is so sad. There is not one time, in my lifetime, that I can remember when a president that I voted for, has taken an initiative to try and do something about our health and well being as a country. I rarely get sick BUT I have ALWAYS made sure that I had health insurance for me and my family "just in case". Same goes for my car insurance or home insurance. You have it, "just in case" and not only that, when something DOES go haywire, aren't you glad you had it to begin with?!
Sandra what is your opinion on the turmoil over in Egypt?
Miss_Net says:
One thing that I do believe should change with the bill is that there should be an option to opt out for those who don't want to be part of it.
The problem with that is healthy people are needed in the pool to offset the medical costs of those with pre-existing conditions like you.
Also healthy people have accidents and when they don't have insurance the rest of us who have insurance pay for it anyway.
Comments are closed for this post


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Funny Marriage Quotes and Sayings - Page 7
I found another word for slave… Groom
When a man goes down on his knees to ask a women to marry him, and she says yes, he remains on his knees forever.
Marriage is like a hot bath, once you get in it, it ain't so hot.
These are great Ihope you don't mind if I share them… I sent you a cup of coffee to enjoy… Thank you for the smiles and laughs…I needed them.
Falling in love is a beautiful experience; Marriage is hitting the rock bottom reality.
Mom: When I married you're father I had to put all my dreams on wait.
Daughter: Really what was you're dream.
Mom: To be single and childless.
Marriage changes Everything!…..Suddenly your in Bed with A Relative!
A married man is like a dead bird, his goose is cooked.
Women marry for prosperity, development and security whereas men marry for enjoyment, destruction and insecurity.
If marriages are made in heaven…
Then it's obvious that someone up there doesn't like us.
Another word for a court judge saying "you are sentenced to life imprisonment with hard labor" is marriage.
Why dogs don't get married? Because they are already leading a dog's life.
Wife: Worries Invited For Ever
Congrats, you're married but for how long again???
I now truly believe "happily married" is an oxymoron.
A woman before marriage is your very best friend, after marriage she's just a plain old' dog.
Marriage rocks! as in a rocky mountain…
I require only three things of a man. He must be handsome, ruthless and stupid.
"Marriage is like a work; it's routinary to serve your partner everyday."
Marriage is a place where two people have to live together for the rest of their lives…or at least until they get divorced!
One day the thunderbolt will hit you, and if you survive that you'll make the dumb mistake of getting married.
The secret to a good marriage is… Divorce!!
Marriage. Man's worst nightmare.


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Cheap and Easy Crafts
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How to Use Pillar Pins
By: CandleWic
If you have trouble with wicks bending inside the candle or leaking at hole of the wick, a pillar pin might simplify the process of wicking in making homemade candles. A pillar pin is an inexpensive tool for those making candles at home and solves many problems with ease.
- Wax
- Pouring Container
- Round Aluminum Molds
- Pillar Pin
You can start with any of the standard 2", 3" or 4" round aluminum molds. Slide the pillar pin into the wick hole (from the outside). The base of the pin should sit flush with the mold. The next step is to take your pillar wax (for best results wax should be a 136 or above) and pour into the mold. Top off as normal and remove. You can then take a pre-waxed wick assembly and slide it into the preformed hole. Then the bottom can be smoothed on a hot plate and the wick base will embed itself in the candle.
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Peugeot to sell logistics business for $1bn
PUBLISHED: 21 Sep 2012 07:49:23 | UPDATED: 21 Sep 2012 07:49:23PRINT EDITION: 21 Sep 2012PSA Peugeot Citron said it was negotiating to sell its Gefco logistics business to JSC Russian Railways for about $1 billion as the French car maker struggles to stay afloat in a faltering European market.
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Brit Floyd Tickets
Brit Floyd is the exquisite band from UK that has taken up the tremendously noble task of performing tributes to the one time, gigantically legendary band Pink Floyd. The Brits were created only recently in 2010 by the talented Chas Cole, who is the CMP Entertainment's Managing Director, and Damian Darlington who is the Musical Director of this wonderful progressive rock group. The band has made an exceedingly fascinating reputation for its live performances by touring across Europe including the United Kingdom. Their live presentations are based on line very parallel to the entertainment tactics of the original Pinks, who were famous for using extensive laser light shows alongside singing. Similarly, their celebratory band includes an intricately set up light show on the main stage with many additional projections, inflatables so that it is at least stylistically representing the Pink Floyd, with particular attention to their Division Bell Tour of 1994, that is frequently termed 'Pulse' tour same as the tour's DVD and album title. The performance glows and glitter have attracted many crowds of fans to get their Brit Floyd tickets within just a short time of their inception.
Brit Floyd Venues
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Latest Brit Floyd Events
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- Sun May 31 2015
In 2010, The Australian Pink Floyd Show (TAPFS) split due to an issue between the directors of TAPFS and CMP. As a result three owners of the show decided to bring in newly assigned management which resulted in their previous management company known as CMP Entertainment to form a completely new band with the fourth owner Damian Darlington who together called their group The British Pink Floyd Show. This name was shortened to Brit Floyd after some time. The band comprises of artists who have all had the opportunity to perform with TAPFS, if not throughout the world then at least in the concerts held in North America. There are only two members in the entire band who have never played with the former TAPFS in their tour of North America through 2008 to 2010. Damian Darlington, in addition, has proved to be the real asset to the group since he has had ample technical and professional experience participating in every performance around the world from 1994 January to 2010 November. He was also present at the performance of 1996 March when TAPFS celebrated David Gilmour's fiftieth birthday in London.
Brit Floyd delivered their earliest performance in January 2011 in Liverpool, at the huge Echo Arena that flocked together a crowd of six thousand people. The rock concert was filmed and recorded for DVD that was soon available to all those who were present at the following concert of the same tour and with their requests made on the group's official website. The Venues selected for the United Kingdom tour included some of the most well-established high-end arenas that are known for their ideal stage settings such as the O2 Arena and the Royal Albert Hall in London. The band then went on to play at Formula 1 Santander British Grand Prix located in Silverstone. The festival shows performed in 2011 included Glastonbury and The Isle of Wight. The Brits have toured rigorously through 2011, performing through Ireland and the UK in Spring, and then going on to play throughout most of Europe and Scandinavia in Autumn.
The band members of Brit Floyd are Damian Darlington, Ola Bienkowska, Emily Jollands, Amy Smith, Jacquie Willliams and Rob Stringer performing the vocals. Arran Ahmun beats the drums, Rick Benhow and Rob Stringer are responsible for the keyboard, whereas Ian Cattell does the bass guitar. Booby Harrison strums the regular acoustic guitar while Carl Brunsdon does multiple instruments including the saxophone, bass guitar, acoustic guitar, percussion, clarinet and the keyboard. Two important personnel members are Gareth Darlington as the front-of-house engineer and key sound designer, and Bryan Kolupski arranges the video, graphics, photography and animnation.
The members of Brit Floyd in collaboration with other big musical acts have performed periodically on tours and other shows under the banner of The Classic Rock Show, which is a concert that popularly covers smashing hit songs from the hottest albums from the seventies and eighties, by master musicians from the likes of The Who and Dire Straits. Get Brit Floyd tickets and attend a real happening rock concert that is sure to sell out the entire arena to an enormous crowd of wildly excited Floyd fans.
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Treasury's Paulson- subprime woes likely contained
NEW YORK, April 20
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NEW YORK, April 20 (Reuters) - U.S. Treasury Secretary Henry Paulson said on Friday the housing market correction appears to be at or near its bottom and that troubles in the subprime mortgage market will not likely spread throughout the economy.
"We've clearly had a big correction in the housing market. Retail housing was growing for some time at a level that was not sustainable," Paulson said in a speech to The Committee of 100, a business group in New York promoting better Chinese relations.
"I don't see (subprime mortgage market troubles) imposing a serious problem. I think it's going to be largely contained," he added.
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After wave of QE, onus shifts to leaders to boost economy
DAVOS, Switzerland - Central banks have done their best to rescue the world economy by printing money and politicians must now act fast to enact structural reforms and pro-investment policies to boost growth, central bankers said on Saturday.


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Event: Centrifugal Compressor Operations for 21st Century Users
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price was right for what we were looking for. An overnight on our way to someplace else. - Anonymous
Very clean, has all the basic amenities, helpful, friendly staff, great price; eady access to airport shuttle - Anonymous
The location in comparison to our travel plans. - Anonymous
like it very much, it,s a great experience and wish to visit it when i come back to NY again. - Anonymous
breakfast was fine - Anonymous
Excellent service, quiet rejuvenating environment. The owners are committed to healthy lifestyle which can be felt throughout your stay. The atmosphere is everything you would want for a weekend getaway. Exceptionally pleasant visit! - Anonymous
Very friendly and helpful staff. Super clean rooms with adjustable beds. Convenient on site restaurant. Will stay here again - Anonymous


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I rather like the animish/awesome design, from the large bayonett *it would be useful just slightly unwieldy in combat* to the styling of the characters
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I rather like the animish/awesome design, from the large bayonett *it would be useful just slightly unwieldy in combat* to the styling of the characters
Sounds just like old R.A2 music and is really awesome. *Gotta build a nice base to it then mass conscripts and A.T*
Don't make the animation too 'fancy' *Just personally i dislike fencers* But otherwise i have no criticism nor comment to make other then Awesome.
shield seems more nod then gdi.
Please fix the spelling and grammatical Issues. Other then that it sounds good.
Once again Sweet picture.
I can't wait till you get a release..ahh..someday.
I purchased the game its only 19.99 on Impulse you can have it within 30 minutes and its alot of fun.
Please support this game.
Let me clarify. Not meaning to say that its bad its actually good.
Kinda Epic. I like background stories and this one is typical of dawn of war. not to say its bad.
Cool but i hope nods is better.
Slightly disappointed *The name made me think their'd be Vein Holes' Other then that Great map though.
As jeff said it is nostalgic.
Awesome I like the Visceroid and damaging vehicles.
It would be awesome if Tiberium mutated people. and did damage to buildings so you had to fight it...and red zone maps would be utterly difficult to fight.
You could even add some abilities to Nod and Cabal/Scrin to manipulate Tiberian growth on a larger scale and add back in the VeinHoles.
I'd like it to be abit more vibrant *and glowing* but not so shiney on its on. Its gotta be abit darker naturally.
No offense not trying to be picky...but could we make the fields flow abit better into eachother?
Although i do see a nice sporetree always like those.
I can wait along time for a 40K Mod. The community almost always does.
make it abit more 'Shiney' and slightly sleaker. Maybe make the beams abit higher and tilt it downward slightly so it'll shine more and look better when firing. *As in tilt the actual banshee down abit while keeping the cannons in the same spot but put the beam abit higher making it look not only more real but shine abit more plus it'll look sleaker..Maybe make the red more like traditional nod red. abit more shine and abit more like fresh blood.
Love the wish there were mods.
I really look forward to this is this for Soul Storm?
Add an extra set of legs behind it *in the back area* for kinetic impact support.
Meaning when it gets hit it can fall back to the back 2 legs *being pushed backward* and they can dig in and stop the impact from destroying it.
It makes technical sense.
I would change the 'head' as it looks like a cockpit which is for cabal not exactly very 'Accurate' as cabal would likely use a computerized system rather then a pilot.
Awesomeness blackzones should be incredibly hostile.
But their should be a Nod Faction that is able to use them to their advantage *Due to nod utilizing tiberian infusion maybe a scientific group that is strong in blackzones? maybe has powers etc. based on tiberian manipulation and some such?*
Where could i find the music from the opening? the simple piano...I can only find the default and the fallfurther but not rise from Erebus opening with the haunting piano melody...
Please tell me where i could find it in the mod folder or the name and artist.
Thank you.
Glad I supported this at the start, it's an amazing game.
I personally dislike changing the government at all. but thats just my opinion.
I just think the 'reich' isn't the same without the leaders they were indoctrinated to believe in *and of course by 1949 alot of kids turning into teens and teens into semi adults* wouldn't have as much of a loyalty or ferocity in serving a different fuhrer.
just a point to make.
Cool. I like how all of their music is techno and jazzy feeling. its calm and relaxed. helps you to be cold and calculating.
Truly the only Good modern vampire games are vampire the masquerade redemption and bloodlines.


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Tag Archives: supra
EVENTS: Pacifico
Pacifico is the first show in southern California by Historic J, who have put on events like the Bayline Gathering, Vintage Auto Salon, and Shokuji J-Tin in the San Francisco area. If the show's name sounds familiar, you might be thinking of … Continue reading
EVENTS: 2014 Japanese Classic Car Show, Part 05 — Made in the 80s
While chrome-bumpered machines from the 60s and 70s are still the Japanese Classic Car Show's core, urethane capped 80s cars are making their presence known in a big way. In this installment we look at iconic cars from the Reagan decade.
Hachimaru Hero ranks the top 80s Japanese cars
Hachimaru Hero (80s Hero) is the Bubble Decade's counterpart to Nostalgic Hero. Both come from the same publisher but nowadays interest in 80s Japanese cars is picking up speed. Recently the magazine put out a reader survey asking for the … Continue reading
EVENTS: 2014 SpoCom
Google "SpoCom" and you'll find more photos of bikinied booth babes than actual cars, but occasionally this "automotive lifestyle" show for the dubstep crowd does turn up some JNC gems. To show you, we dodged legions of rehearsing dance crews, suffered loud electronic distortion … Continue reading
ART CORNER: Fujimi's Touge Series Box Illustrations
Long after earning driver's licenses and pinkslips to our rides, some of us still find ourselves mired in plastic model cars. Perhaps it reflects the constraint suffered by many of us on budget, space, or sanity (of ourselves and/or family … Continue reading
KIDNEY, ANYONE? 57-mile MA71 Toyota Supra Turbo
Yes, you read that right. 57 miles. 92 kilometers. That's the odometer reading of this Canadian MA71 Toyota Supra Turbo, likely a dealership showpiece for nearly 25 years. Now it's being offered by County Hills Toyota-Scion in Calgary after a lifetime of being … Continue reading
EVENTS: 2014 All-Toyotafest, Part 04 — Museum Pieces
For our final installment of Toyotafest coverage, we bring you the museum-worthy cars that put meaning to the word classic. Whether its racing provenance, rarity, pop culture status or just a stupendously fantastic specimen, these are the cars that are should be exhibited and preserved as inspiration … Continue reading
EVENTS: 2014 All-Toyotafest, Part 01— Luxe & GT
Hanging like a cloud over the festivities of the 19th annual All-Toyotafest this year was the news that had been leaked to the press a week prior: Toyota USA was moving its headquarters, which had been a southern California fixture … Continue reading
19th Annual All-Toyotafest, a preview
JNC on the way to the 19th annual All-Toyotafest, stopping for an early morning breakfast of champions. Supra-size me!
2014 All-Toyotafest, a reminder
There are only three days till the 19th annual All-Toyotafest. As usual, JNC will be there with a booth, and we'll be making the drive in this black 1980 Toyota Supra. Stop by and say hi. As it happens, the day of … Continue reading


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New to Typophile? Accounts are free, and easy to set up.
I have an alternate "t" with a rather long raised crossbar and another one with no crossbar at all. Is there some smart way I can create an opentype feature that let's me substitute my regular t's with these two in a word like this: txxxxt (x = any given lowercase letter)
Would this work?
First create a class of lowercase glyphs, @x.
sub t @x @x @x @x t' by t.nobar ;
sub t' @x @x @x @x t.bar by t.highbar ;
Do you mean you want this to occur when exactly four lowercase characters occur between the t's, or do you intend this to work with an arbitrary number of characters separating the two t's?
Thanks Nick. André: Arbitraty, but I'll probably have to have a maximum number, and also something that would work for a word like "retrett".
Sounds difficult, as the intervening letters could be quite different widths.
Nick, does your second line need to say t.nobar rather than t.bar?
This is a handwritten script. The crossbars will be rather freeflowing, so I'm ok with different widths.


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This game is a part of the 2010 Kansas High School Football Playoff Bracket - 3A tournament. These two teams meet in round 3 (Quarterfinals). You can view the full bracket here.
(November 12, 2010: Beloit, KS 67420) The Trinity Celtics football team (Hutchinson, KS), was knocked off 38-12 in Friday's non-league challenge with the host Beloit Trojans (Beloit, KS)
The Celtics now sport a 10-2 record.
Not a Member? Join MaxPreps now for free access to rankings for thousands of teams across all sports. IT'S FREE, IT'S FAST, IT'S EASY!


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Dr. Anju T. Peters, MD
Allergy & Immunology, Northwestern Medical Faculty Foundation
- 675 N Saint Clair St Ste 18-200
Chicago, IL 60611 - 1 Office Location
- (312) 695-9400
Dr. Anju T. Peters graduated from the University of Michigan Medical School in 1993. She works in Chicago, IL and specializes in Allergy & Immunology. Dr. Peters is affiliated with Northwestern Memorial Hospital. She speaks English and Spanish.
Gender: Female
Years in Practice: 22 Years
Languages Spoken: English, Spanish
Medical School: University of Michigan Medical School
Graduation Date: 1993
Hospital Affiliations: Northwestern Memorial Hospital
Specialties: Allergy & Immunology


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A few photos of my M and lenses with a bit of bling
Re: A few photos of my M and lenses with a bit of bling
In reply to bugbait,
Nov 7, 2013
I think your camera looks very cool. Distinctive for people shooting.
For my needs your effect might be a bit scary for insects that I often photograph, looks a bit like feathers or something.
I have gone the opposite way with function over formality. I added this silicone case for shock absorption and weather resistance.
But as you can see below from this fast mirror image, I have blacked out Canon and actually cut small grooves into the front grip to make it all the more grippy. The back of the case already has a very nice grip. I may make a tight fitting camouflage cover to go over most of it. I have put electrical tape over the side inputs as I do not use them so no need to allow them t potentially short circuit anything. The case also came with two rather good screen protectors. It has not affected the touch sensitivity. As for cutting grooves into silicone I happen to have wax carving tools that are ideal, they just scoop the material away. It is not pretty but handles very well.
I think the insects will scared right away when they see that silicone case!
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Jessica Simpson Kiss Me Jegging
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- Low rise zip fly stretch legging jean
- Slim through the hip and thigh
- 10" bottom opening
- Embroidered logo on back pockets
- Leather Jessica Simpson logo label on back
- 98% Cotton, 2% Spandex.
- Machine wash in cold water with like colors. Use only non-chlorine bleach when needed. Tumble dry low. Warm iron if necessary.
- Made in China.
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4:12 pm
Thu December 16, 2010
Water will Continue to Flow
By KWGS News
Tulsa, OK – A reprieve for the residents at the Somerset East Apartment complex near the old Eastland Mall. The city will delay cutting off the water to the complex until January 3rd. It was to have been cut off today because the complex owner is about 70-thousand dollars past due on his water bill. The residents are thankful for the city's action, but furious at the complex's out of state owner.
The city will also have the trash hauled away. Dumpsters have not been emptied since the complex defaulted on its trash bill three weeks ago.


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Norwich City
Scorchers win BBL title on final ball
IT was so close to being a fairytale ending for Brett Lee, but it was the Perth Scorchers who claimed back-to-back BBL titles with a thrilling win.
Simp-Lee amazing end to a great career
THE last of Brett Lee's 2,706 deliveries in Twenty20 cricket was very different to his first. There was only one thing that hadn't changed.
Teen sensation shocks the Open
MADISON Keys started playing tennis at age four because she liked the way Venus Williams dressed. Today, Venus wishes she'd worn something different.
The Super Bowl's big drama explained
DEFLATEGATE. By now you may have heard the term in passing. Over the next week, you'll be hearing it a lot more. This is the scandal rocking the NFL.
Stan, Serena, Djoker cruise into semis
NOVAK Djokovic will face Stan Wawrinka while Serena Williams and Madison Keys will clash in the semi finals. RE-LIVE IT
Millionaire cricketer causes Twitter storm
YOU may remember Stuart Broad as Australia's public enemy No. 1 during the 2013 Ashes series. Now he's created controversy once again.
Halfway in the NBA: Aussie report card
WE'RE a little more than halfway through the NBA season and it's time to check on the progress of all seven Australians plying their trade in the big time.
Wrong direction: Did Kyrgios snub Niall?
TO BE fair, he had just suffered a grand slam loss, so Nick Kyrgios had every reason to be distracted off court. No wonder he didn't notice this famous star.
Meet the man behind Smith's success
HE'S the man behind Steve Smith's incredible rise to the top of Australian cricket, and yet remains in the shadows.
'Mercedes' room for improvement is small'
DANIEL Ricciardo says engine development changes will help Red Bull as they attempt to close the gap to Mercedes.


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Located in Salinas, California, the town known as the "Salad Bowl of the World" it is only fitting that Alisal Union School District would have a true commitment to nutrition in the cafeteria and in the classroom. Under the leadership of the Director of Food Services, Suzanne DuVerrier and in partnership with Community Alliance with Family Farmers, the Alisal Union School District introduced cafeteria salad bars to all 11 schools in the district and installed gardens at nearly half of the district's schools. Additionally, a pilot Farm to School program has been implemented in two schools, combining the salad bar with farm-fresh produce, nutrition and physical activity education, and garden-based activities. The district has also passed a school food policy mandating that, among other things: fresh, local produce be offered on the school menu when possible; that soda and other beverages of questionable nutritional value not be sold on campus or distributed by teachers; and that teachers should model good nutrition and fitness for their students.
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Carter's Corner | Brown Bear | James Reed
The North American Brown Bear is America's apex predator. And without doubt ranks as truly dangerous big game. Early September found Sports Afield's James Reed in search of a big brown bear along the salmon streams of southeast Alaska. Hunting these big grizzlies along the salmon streams promises close encounters where instant target acquisition and close range make the 1-4x AccuPoint a perfect choice.
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Carter's Corner | Brown Bear | James Reed
PoliceOne top 5
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- 5 Video: Minn. officer shot to death during traffic stop