text:
Enter your Email address:
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy.
You currently have no recent searches
Helbig, Grzegorz
Department of Hematology and Bone Marrow Transplantation, Silesian Medical University, Katowice, Poland
Correspondence to Grzegorz Helbig, MD, PhD, Department of Hematology and Bone Marrow Transplantation, Silesian Medical University, 40-032 Katowice, Dabrowski Street 25, Poland. Tel: +48 322591310; fax: +48 322554985; e-mail: email@example.com
Purpose of review: Eosinophils play an important role in the pathogenesis of allergic, infectious and malignant diseases. Over the last decade, new diagnostic tools and treatment modalities have led to the re-evaluation of the existing definition of eosinophilic disorders. This review discusses a recent proposal for new terminology and classification of hypereosinophilia. The results of targeted therapy for hypereosinophilia-related disorders are also summarized.
Recent findings: A panel of multidisciplinary experts agreed on unifying definitions and criteria of eosinophilia-associated disorders and created a new classification of hypereosinophilia-related conditions based on clinical, haematological and laboratory findings as well as the underlying cause of hypereosinophilia. Recent results of the treatment of idiopathic hypereosinophilic syndrome (HES) with the anti-interleukin 5 monoclonal antibody mepolizumab showed its efficacy and manageable safety profile. The treatment of platelet-derived growth factor alpha (PDGFRA)-positive HES with imatinib demonstrated long-lasting efficacy and low likelihood of drug resistance.
Summary: The unifying terminology and definitions should aid physicians caring for patients with hypereosinophilia. Despite much progress, serum biomarkers correlate with disease severity and predict responses to treatment that are needed. There is also a great need for understanding and specific therapy for PDGFRA-negative HES.
Eosinophils play a pivotal role in inflammatory processes, tissue injury, remodeling and fibrosis. Eosinophil development and differentiation in the bone marrow is mediated by specific transcription factors. Maturation and exit from the marrow is promoted by eosinophilopoietic cytokines, mainly interleukin (IL)-5, but also granulocyte-macrophage colony-stimulating factor and IL-3. Activated T cells remain the primary source of IL-5; IL-5 is regarded as playing an essential role in the promotion of reactive eosinophilia in blood and marrow in allergic and parasitic diseases, as well as in Churg–Strauss syndrome (CSS) and some variants of hypereosinophilic syndrome (HES). Exposure to IL-5 is known to prolong the survival of eosinophils and promote the secretion of eosinophil granule contents [1].
The central role of IL-5 in the development and functioning of eosinophils has prompted the development and studies of anti-IL-5 monoclonal antibodies as steroid-sparing agents for several eosinophilia-associated disorders. Studies have demonstrated the effectiveness of this treatment strategy [2–4].
In response to a variety of stimuli, eosinophils are activated and invade most organ systems, thereby causing organ dysfunction and disease. Typically, eosinophils in peripheral blood represent less than 5% of total leukocytes, Eosinophilia is defined as absolute blood eosinophil count (AEC) exceeding 0.5 × 109/l. Hypereosinophilia refers to AEC greater than 1.5 × 109/l [5]. It should be mentioned that tissue eosinophilia may be accompanied or not accompanied by blood eosinophilia and vice versa. Whereas a modest number of eosinophils are found in normal tissues, for example, the gastrointestinal tract, their excessive infiltration may result in organ damage and lead to local or systemic disease. Hypereosinophilia is associated with inflammation, tissue fibrosis and has a tendency to cause thrombosis presumably because of tissue infiltration by eosinophils and release of their granule contents. This may impair the function of critical organs, for example, heart, lungs or central nervous system. The candidate mechanisms by which eosinophils cause tissue damage have been proposed and this was presented in detail elsewhere [6]. This current review will focus on the recent clinical advances in the field of eosinophilia.
The introduction of new diagnostic tools and treatment modalities has prompted modification of the existing criteria of HES established nearly 40 years ago [7]. Some key questions are as follows:
1. Should a HES patient remain untreated for 6 months despite features of organ dysfunction?
2. How should the clinician manage a patient with blood hypereosinophilia without signs of tissue infiltration?
3. What is the proper classification for a patient with eosinophilia-associated organ damage and AEC less than 1.5 × 109/l?
4. How should a patient, originally diagnosed as idiopathic hypereosinophilia, be classified after the identification of a fusion gene involving platelet-derived growth factor receptor α (PDGFRA) [8]?
To deal with these important questions, experts first recommended that the original Chusid criteria for HES should be loosened, with the requirements for the duration of hypereosinophilia as well as the degree of eosinophilia modified when there is documented organ damage [9]. Then a panel of multidisciplinary experts agreed on new terminology, criteria and classification of eosinophilic disorders [10▪▪]. The most important new findings can be outlined as follows:
1. The term hypereosinophilia should be used when the AEC is greater than 1.5 × 109/l on two occasions with a minimum of a 1-month interval. The exception is when the AEC is greater than 1.5 × 109/l and there is life-threatening organ dysfunction and/or tissue eosinophilia is documented. For the diagnosis, the following criteria should be met: eosinophils should constitute more than 20% of all nucleated cells in the bone marrow section; massive tissue infiltration by eosinophils should be found in tissue biopsies by pathologic study; and specific staining should reveal local deposition of eosinophil-derived contents.
The proposed classification of hypereosinophilia includes four variants that are as follows:
1. familial clustering with unknown pathogenesis;
2. asymptomatic eosinophilia of undetermined significance with no known underlying cause (HEus);
3. neoplastic eosinophilia with the evidence of myeloid/eosinophilic clonality;
4. reactive eosinophilia mostly cytokine-driven with known underlying nonclonal cause.
According to a new proposal, the patients with an aberrant T-cell population in blood and hypereosinophilia-associated organ damage are now regarded as a variant of reactive HES.
HES patients generally require treatment, but the management of patients with severe blood hypereosinophilia without organ involvement is challenging. The expert panel proposed the term HEus for patients with benign, idiopathic hypereosinophilia; but there was no consensus regarding the therapeutic management for HEus patients. Treat or not to treat? – this question remains open.
In my opinion, this new diagnostic terminology accurately reflects this patient population. It also clearly indicates the need for long-term follow-up information on these patients, similar to the need for more information about patients with monoclonal gammopathy of undetermined significance [11]. In my practice, I follow patients with eosinophilia at 3–6 month intervals. In my observation, patients may remain asymptomatic for months or even years despite the long-lasting elevation of blood levels. When AEC is greater than 5.0 × 109/l, I usually start treatment with corticosteroids in order to avoid end-organ damage, but this management is not supported by literature data. Others prefer to implement the treatment with higher counts, for example, AEC exceeds 30 × 109/l, but this is, again, not endorsed by the evidence [12].
The identification of organ damage in a patient with HEus is synonymous with the HES diagnosis and, when present, the initiation of treatment is inevitable. A major challenge regarding the HEus patients is to define the risk factors that may predict the transformation to HES, but such data has yet to be published. The definition of eosinophilia-attributable organ involvement is another problem. As was mentioned previously, histological evidence of tissue eosinophila is absolutely necessary for the diagnosis of HES. However, it is extremely difficult to implement this criterion in clinical practice because the involved organs are often inaccessible for biopsy or the biopsy procedures are associated with high risk of severe complications. Imaging studies are often inconclusive. From a practical point of view, the diagnosis of hypereosinophilia-related organ dysfunction is often made by the exclusion of other causes, as in a recent report of a large series of HES patients [13].
The expert panel proposed clinical and laboratory parameters to be performed on patients with hypereosinophilia [5], but the list of recommended investigations was long and expensive. For example, immunophenotyping of T cells by flow cytometry as well as molecular assays by PCR are not widely available and can be performed only in specialized laboratories. Although samples may be shipped for some of these tests, there is a clear need for simplified diagnostic methods and specific biomarkers that accurately predict prognosis for these patients.
Eosinophils exhibit a variety of characteristic alterations when activated [5]. Sialic acid immunoglobulin-like lectins (Siglecs) are cell surface proteins found predominantly on leukocytes. Siglec-8 is uniquely expressed on eosinophils and mast cells and weakly on basophils [14]. This protein is engaged in apoptosis of human eosinophils, and IL-5 priming increases Siglec-8-mediated apoptosis, a finding that may have a potential clinical implication [15]. In fact, studies in IL-5 transgenic mice with hypereosinophilia have shown that administration of an antibody directed against Siglec-8 resulted in a prompt and significant reduction of blood eosinophilia [16]. Thus, Siglec-8 may be a promising target for monoclonal antibodies in eosinophilia-related conditions [17]. Recently, a novel assay for the measurement of serum Siglec-8 was developed, but its utility needs to be validated [18].
A variety of serum cytokines and chemokines have been used as markers of different eosinophilia-related disorders. Some of them were found to be elevated in patients with active CSS and also in HES patients. Therefore, they may not serve as biomarkers distinguishing between these disorders [19,20]. These findings have been confirmed in a large retrospective study including CSS and HES patients. Despite the fact that some serum markers were elevated in CSS/HES when compared with healthy controls, there were similarities between eosinophilia-related conditions [21]. Recently, Wilson et al.[22] reported on serum IL-5 receptor α (IL-5Rα) levels in patients with blood eosinophilia including patients with idiopathic HES and PDGFRA-positive HES. It was demonstrated that serum soluble IL-5Rα levels correlated positively with blood AEC and that an elevation of the serum IL-5Rα levels was associated with increased serum IL-5 and IL-13 levels and other markers of eosinophil activation. An inverse correlation was found between surface expression of IL-5Rα on blood eosinophils and AEC. These results may have clinical implications with respect to novel agents targeting IL-5Rα [23].
The therapeutic approach to eosinophilic disorders has changed during the past several years. The identification of specific targets may influence the prognosis and improve the quality of life. Benralizumab is a humanized monoclonal antibody targeting IL-5Rα, and this compound has been tested in a phase I study of patients with asthma. This treatment resulted in marked decrease of AEC as well as serum eosinophil cationic protein levels [23]. Taking into account these promising results, the further studies of individuals with CSS/HES are expected to be initiated. Another IL-5 targeting agent, mepolizumab, has been investigated for the treatment of many eosinophilic disorders including HES. A randomized, placebo-controlled study of 85 HES patients receiving prednisone at 20–60 mg daily (q.d.) was designed in order to evaluate the efficacy of mepolizumab as a steroid-sparing agent. The primary end point of a reduction of the prednisone dose to 10 mg daily or less for eight or more consecutive weeks was achieved in 84% of patients on mepolizumab if compared with 43% in the placebo group [2]. Recently, the results of mepolizumab treatment for PDGFRA-negative HES were reported, confirming its high efficacy and manageable safety profile as a steroid-sparing agent in long-term observation [24▪]. Alemtuzumab, an anti-CD52 antibody, has been reported to be effective for refractory HES patients [25]. Twelve patients were included in this retrospective analysis; 10 (83%) achieved complete hematologic response and the remaining two individuals met partial response criteria. It was found that alemtuzumab maintenance for patients in remission resulted in a significantly longer progression-free survival if compared with the patients who did not continue the antibody treatment [25]. Alemtuzumab may be an alternative therapeutic option for HES patients who failed prior therapy and are not candidates for allogeneic stem cell transplantation, but it appears to be a relatively expensive and poorly tolerated treatment. Targeted therapies for eosinophilic disorders that are currently available or in clinical trials were presented in a recently published review by Wechsler et al.[26▪].
Despite the progress that has been made in the development of targeted agents, the glucocorticosteroids and hydroxyurea remain the cornerstone of therapy for PDGFRA-negative HES [13]. Our group reported on the results of steroid treatment for 33 patients with HEus and idiopathic HES. The median starting dose of steroids was 30 mg daily and 64% of treated individuals achieved complete remission. In our study, therapy was well tolerated with only a single case of severe gastric complications. In another report, imatinib mesylate was found to be effective in three out of seven steroid-resistant or intolerant patients [27].
The updated results of imatinib mesylate treatment for PDGFRA-positive HES were published last year from the Mayo Clinic. Twenty-two patients with mutated FIP1L1–PDGFRA (F/P) were identified and, of these, 18 were treated with imatinib mesylate. Most patients (77%) received imatinib mesylate at 100 mg daily. One individual was found to be intolerant to imatinib mesylate, the remaining 17 patients achieved complete remission. Median follow up of the imatinib mesylate-treated population was 6 years. These results confirmed the impressive response to low doses of imatinib mesylate with the low probability of developing secondary resistance. However, the authors' conclusion is that the therapy with imatinib mesylate should be continued indefinitely [28].
Our results are in line with those of the Mayo study. Twenty-five patients with mutated F/P received imatinib mesylate at a starting dose of 100 mg daily. All responded promptly and after a median follow up of almost 6 years remained in remission. Imatinib mesylate at 100 mg weekly was found to be sufficient for response maintenance. However, in contrast to the final statement of the Mayo Group, we discontinued imatinib mesylate therapy in two patients who had negative PCR in consecutive assays for 5 years and they are still disease-free with more than 1 year being off therapy [29]. The presence of PDGFRA mutation in eosinophilia-associated acute leukemia or lymphoma was also associated with very impressive and sustained responses to imatinib mesylate despite the failure of prior therapy with conventional chemotherapy [30]. Most F/P-positive patients are adult male and only single case reports included children. Only four F/P-mutated children have been described in the literature so far. Three children received imatinib mesylate with excellent responses [31].
In contrast to the previously mentioned population with PDGFRA mutations, there is a lack of long-term survival data for individuals with PDGFRA-negative HES. Podjasek et al.[32▪] presented the 19-year experience of HES-related mortality at Mayo Clinic, probably the largest report published. The study included 247 HES patients, of whom 23 died (10%), but the cause of death was identified in only 15 patients. Most individuals died of presumably eosinophilia-attributable cardiac damage and unrelated infections and malignancies. Only two patients developed thrombotic phenomena likely to be secondary to HES. Unfortunately, there are no data on histologic studies of affected organs. Moreover, blood eosinophilia before death was only available for a small minority of these patients.
In summary, in 2013 important changes were introduced to better define and classify patients with hypereosinophilia. With the exception of PDGFRA-mutated HES cases, the molecular mechanisms remain unknown for the vast majority of these patients, and therefore targeted therapy is not possible. On the other hand, we are witnessing rapid development of monoclonal antibodies targeting IL-5/IL-5Rα, but thus far these agents are not available beyond clinical trials. Steroids and hydroxyurea remain the first-line therapeutic options for the HES population, but their long-term administration may be associated with severe side-effects. IL-5/IL5Rα are promising targets currently being investigated. Treatment of PDGFRA-positive HES with imatinib mesylate results in an excellent response rate, long-term efficacy and a low likelihood of drug resistance. The question remains open whether these patients will be cured following imatinib mesylate discontinuation. Future studies should focus on a better understanding of the pathogenesis of HEus. The other challenge is to identify the serum biomarkers that may predict disease severity and responsiveness to therapy. Better diagnostic tools are also required for the evaluation of eosinophilia-related end-organ damage.
There are no conflicts of interest.
Papers of particular interest, published within the annual period of review, have been highlighted as:
▪ of special interest
▪▪ of outstanding interest
A summary of the recent developments in the pathogenesis and classification of eosinophilic disorders.
This article reports on safety aspects of anti-IL-5 antibody treatment for hypereosinophilic syndrome.
A comprehensive review of the targeted therapies for eosinophilia-related conditions.
A large review reporting the main causes of death in patients with hypereosinophilic syndrome.
classification; eosinophilia; hypereosinophilic syndrome; treatment
© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Colleague's E-mail is Invalid
Your Name: (optional)
Your Email:
Colleague's Email: Separate multiple e-mails with a (;).
Message: Thought you might appreciate this item(s) I saw at Current Opinion in Hematology.
Send a copy to your email
Your message has been successfully sent to your colleague.
Some error has occurred while processing your request. Please try after some time.
An Existing Folder
A New Folder
Folder Name:
The item(s) has been successfully added to "".
Login with your LWW Journals username and password.
Username or Email:
Forgot Password?
Enter and submit the email address you registered with. An email with instructions to reset your password will be sent to that address.
Link to reset your password has been sent to specified email address.
What does "Remember me" mean? By checking this box, you'll stay logged in until you logout. You'll get easier access to your articles, collections, media, and all your other content, even if you close your browser or shut down your computer.
To protect your most sensitive data and activities (like changing your password), we'll ask you to re-enter your password when you access these services.
What if I'm on a computer that I share with others? If you're using a public computer or you share this computer with others, we recommend that you uncheck the "Remember me" box.
Save my selection
Keyword Highlighting Highlight selected keywords in the article text.
Search for Similar Articles You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.


text:
More Videos...
07 350z with GReddy EVO2 exhaust 07 with just GReddy cat-back Exhaust, resonated test pipes are coming soon...
'07 350z Greddy Evo2 Exhaust 2007 nissan 350z with greddy evo-II Exhaust and stillen high flow cats as well as nismo dual cold air intakes. WARNING ANY DAMAGES TO SPEAKERS DUE TO WATCHING THIS VIDEO WILL BE AT OWNERS RESPONSIBILITY! ENJOY ;-)
2007 Nissan 350Z 500+HP Greddy Twin Turbo Motordyne TDX Exhaust -Test Drive Drag Burnout to contact us with sales questions visit http://www.vivalasvegasautos.com To view our blog, go to http://vivalvautos.blogspot.com Standard Equipment 3.5 Liter DOHC V6 Engine 306 horsepower @ 6,800/268 ft-lbs torque @ 4,800 RPM * Variable Valve Timing Close Ratio 6-Speed Manual Transmission Front Engine/Rear Wheel Drive Engine Speed Sensitive Power Rack and Pinion Steering 4-Wheel Power Disc Brakes with ABS and Brake Force Distribution 4-Wheel Independent Suspension with Rear Shock Tower Brace Carbon Fiber Composite Driveshaft Power Windows Power Heated Outside Mirrors Power Locks Remote Keyless Entry Bi-Xenon HID Head Lights LED Park and Tail Lights Tire Pressure Monitoring System Air Conditioning with Automatic Climate Control Fuel, Temperature, 9,000 RPM Tachometer and 160 MPH Speedometer 3-Bay Gauge Cluster: Trip Computer, Oil Pressure and Volt Gauges Multi-Function Trip Computer Overhead Console with Mao Lights and Glasses Storage Tilt Steering Column with Integrated Gauges Shift-Up Indicator Center Floor Console with Storage and Locking Rear Box Dual Lighted Visor Vanity Mirrors with Visor Extenders AM/FM/CD Audio with 6-Speakers * 8-Way Manual Driver's Seat Leather Wrapped Steering Wheel Leather Wrapped Shift Knob and Emergency Brake Handle Brushed Aluminum Interior Trim Dual Stage Driver and Passenger Airbags with Seatbelt/Occupant Classification Sensors Seatbelt Pretensioners and Load Limiters Driver and Passenger Side Knee Support Vehicle Security System with Immobilizer Front and Rear Power Outlets 5-Cup Holders Passenger Side Storage Net Intermittent Wipers Rear Wiper Rear Defrost Tinted Glass Carpeted Floor Mats Rear Cargo Mat 20-Gallon Fuel Tank * These items upgraded and/or replaced. Optional Equipment Enthusiast: Traction Control Limited Slip Differential Drilled Aluminum Pedals and Dead Pedal Illuminated Steering Wheel Controls Cruise Control HomeLink Universal Transceiver Auto-Dimming Rear View Mirror Additional Items GReddy 20g Twin turbo Kit with Two (2) TD06 SH-20G turbochargers, Intake Piping/Filters and Type 20 Intercooler Heat Wrapping (all turbo and Exhaust parts down to cats) HKS EVC 6 Boost Controller HKS turbo-Timer Walbro 255LPH Fuel Pump Deatsch Werks 600cc Injectors Motordyne TDX High Polished Stainless Steel Exhaust System Ti Blu Titanium Exhaust Tips Jim Wolf Tech Heavy Duty Clutch Jim Wolf Tech Flywheel Pioneer AVIC Z120BT Head Unit with 7-Inch LCD Screen, DVD/Bluetooth/iPod Connection Two (2) JL Audio 10-Inch W3 Subwoofers in JL Audio Stealth Box JL Audio 1,000 Watt V2 Amplifier HKS Comp2 System (view gauges/systems on stereo LCD screen) Black Chrome X Logo Trunk Badge Volk Racing RE30 19 x 10 (front) and 19 x 11 (rear) Forged Aluminum Wheels Volk Center Caps and Valve Caps Bridgestone Potenza RE-11 Steel Belted Radials 265/35R19 (front) 285/35R19 (rear)
Subaru WRX - Greddy SP Elite Exhaust Some footage of different driving scenarios with the Greddy SP Elite CBE. Wish I got more out of car footage, but this will do for now. Enjoy!
Scion FR-S Greddy SP Elite Exhaust Greddy SP Elite catback (axelback)
Greddy EVO TT 350Z stock engine .... this is the before engine build/greddy twin turbos/sgp open dump install...after install movie coming soon
Greddy Evo2 Exhaust Greddy Evo-II Exhaust
2005 350z GReddy EVO2 exhaust 2005 350z GReddy EVO2 Exhaust, resonated test pipes, JWT POPcharger
Greddy Ti-C Dual Exhaust [HD] - 2005 Honda S2000 AP2 You ever wanted to know how the Greddy Pipes sound on the Honda S2000?
Stock 350z exhaust vs HKS hi powered 2008 350z HKS hi powered Exhaust and a AEM cold air intake
L-SCHLEGS 08 STI - Greddy TI-C Exhaust - Equal Length Headers Watch in HD! Edit of my car with sound clips of my newest Exhaust. Perrin Equal length headers to P & L custom catless downpipe and Greddy Ti-C Catback. The car is stock motor with a rotated 35r. It puts down 447whp and 395wtq. You can view more of the car and mod list here: http://www.iwsti.com/forums/gr-members-journals/149393-l-schlegs-08-sti-447 -whp-395-wtq-rotated-35r-prodrive-bride-seibon-more.html ps....I shoot a massive flame at like 1:20 :)
GReddy 35RX GT-R - Fuji Speedway Top Speed Challenge Visit http://greddy.com/products/jdm-special-order/R35-GTR/ for more information. TRUST, Japan R&D project for Top Speed Challenge, GReddy 35RX GT-R. Fearless Option Video driver Tarzan Yamada takes to the Fuji Speedway for high speed test, over 200mph! 1250ps via GReddy 4.3l stroker engine and twin TD06-20G Twin turbo kit. Type-29 Intercooler, DCT Cooler kit, DCT cooling pan, high-flow Intake Manifold, GReddy Exhaust. Art Factory LIvery. BenSopra wide-body Aero kit. https://www.facebook.com/GReddyRacing http://www.trust-power.com/ http://greddy.com/
BEST of Start Up sounds!! More than 70 Exhaust Sounds! To celebrate my 600th video, I have made this compilation: probably all the start up sounds from supercars I've recorded in the past years. It's the largest start-up sound compilation on YouTube right now! I have put them together in one video with more than 70 start up sounds! What's you favorite start up sound? Let me know by leaving a comment behind! PART 2: http://youtu.be/hgz22nhf5ZQ Follow me: http://www.Gumbal.tv 1st Channel: http://www.YouTube.com/GUMBAL 2nd Channel: http://www.YouTube.com/GUMBALTV 3rd Channel: http://www.YouTube.com/CarChannelClassic FACEBOOK: http://www.fb.com/GUMBALTV INSTAGRAM: http://www.instagram.com/GUMBALTV TWITTER: http://Twitter.com/GUMBALTV GOOGLE+: https://plus.google.com/+Gumbal Thanks you for watching my videos. All feedback on my videos are appreciated! Don't forget to like the video and subscribe to my channel. More videos coming up! - Hans
GReddy Racing FR-S - Behind the Build Get a behind the scenes look at the development of the Scion Racing/GReddy Racing Scion FR-S. Sit down with Kenji Sumino, Ken Gushi, and others as they discuss the process behind preparing the FR-R for the first event of the 2012 Formula Drift season.
Scion FR-S Greddy Evo 3 Catback Invidia Catless DP Scion FR-S Greddy Evo 3 Catback with Invidia Catless Downpipe.
Tesla Model S P85D Insane Mode Launch Compilation Video
McLaren MP4-12C Alpha Performance Tune Testing
Tesla Model S P85D vs Mercedes E63s AMG 1/4 Mile Drag Racing
Lamborghini Aventador LP720-4 1/4 Mile Launch Control Demo 11.3 @ 133.4 MPH
Which car is faster?
Similar 1/4 mile timeslips to browse:
1995 Nissan 350Z Single Turbo: 9.340 @ 145.470 gbaker, Engine: 3.5L VQ35DE, 8500rpm redline, Turbos: Garrett GT42R 76mm Ball-Bearing Single Turbo Tires: MT 305/35-18 Drag Radials
2003 Nissan 350Z Touring Stock Motor Vortech V2 SC-Trim: 10.954 @ 127.560 TimRod, Engine: Total Stock Motor, Never touched, Supercharger: Vortech V2 SC-Trim Turbos: None Tires: 28 x 10.50 x 15 ET Drags
2003 Nissan 350Z Twin Turbo Touring 6MT: 10.967 @ 126.840 Brian Vogelsinger, Engine: VQ35DE, Turbos: Twin Garrett GT2871R Tires: MT ET street radials
2003 Nissan 350Z Track Greddy Turbo: 11.190 @ 126.180 Alberto, Engine: 3.5L, Turbos: Greddy Tires: ET Streets
2004 Nissan 350Z TT 700BB: 11.378 @ 128.210 zorrotsi, Engine: VQ35DE, Turbos: JWT 700bb Tires: mt et streets
2005 Nissan 350Z Twin Turbo: 11.470 @ 131.960 sbaset, Engine: 3.8L Darton sleeved shortblock,
2003 Nissan 350Z APS Twin Turbo: 11.536 @ 120.800 Brian Vogelsinger, Engine: stock, Turbos: APS Twin Turbo kit Tires: MT ET street
2004 Nissan 350Z touring JWT 700BB Turbo: 11.560 @ 125.060 Rafa, Engine: VQ35DE, Turbos: JWT 700BB Tires: MT STREET
2005 Nissan 350Z Extreme APS TT: 11.618 @ 124.820 Manuel Ferro, Engine: Built, Turbos: Extreme APS TT
2003 Nissan 350Z touring: 11.833 @ 115.530 jeremy tibbs, Engine: vq35de,
2003 Nissan 350Z Track Single Turbo: 11.875 @ 124.058 Shon (me), Engine: VQ35, Turbos: Turbinetics Tires: 225/40/18 front 245/40/18 rear
2003 Nissan 350Z performance: 11.937 @ 123.821 Steven, Engine: 3.5L VQ35DE, Supercharger: none Turbos: none Tires: 275/40/18
2006 Nissan 350Z Base: 12.051 @ 112.900 Jon Stevenson, Engine: Stock, Supercharger: N/A Turbos: N/A Tires: BFG Drag Radials 295/35-18
2003 Nissan 350Z Nitrous Express: 12.052 @ 113.670 Integrity, Tires: ET Streets
2004 Nissan 350Z Touring Nitrous: 12.055 @ 112.500 Jerome, Engine: 3.5L, Tires: MT Slciks
2005 Nissan 350Z Enthusiast Twin Turbo: 12.100 @ 115.590 Thomas Hornig, Engine: VQ35DE, Turbos: APS TT Tires: MT ET Street rear, Toyo T1R front
2004 Nissan 350Z Touring: 12.255 @ 112.910 Stephen Kirouac, Engine: VQ , Turbos: TN Single Tires: Drag Radials
2005 Nissan 350Z Touring Vortech Supercharged: 12.282 @ 114.290 Sveinn Elíasson, Engine: VQ35DE, Supercharger: Vortech V2 Tires: Mickey Thompson E/T Street 16
2007 Nissan 350Z Base Supercharger Stillen: 12.322 @ 117.500 Edgar Guerrero, Supercharger: Stillen Tires: Drag radials 275/40/17
2003 Nissan 350Z Single Turbo: 12.345 @ 113.370 Craig L, Engine: vq35de (stock internals), Turbos: Turbonetics 60-1 ball bearing Tires: Falken FK-451 STREET TIRES
©2015 DragTimes - Disclaimer - Contact Us

subset: commoncrawl


text:
Vot (in halat) alb
Ppop vs. Brushvox
Lovageddon Suicide
The Fatter of Mact
Doomstep Prophecies
Los Josus [EP]
Mashed, Scratched, Trashed
The Ghost of the Absent Father
Badtime Stories
Mr. Pan[k]sament with Oedip Piaf
Faking the Tree
Chasing Shadows
All the Best, from Bucharest!
One Bullet [REsolution]
New Blues
Frust-Rated XXX (1999)
Nation's Slum
Back to the Basement (1992)
Mr. Pan[k]sament Romania
I had ended up at the microphone of a garage rock band back in 1988 by mistake and fortune and ever since I'm "doing" music
one way or another with different bands or by my own. I played piano, bass, guitar, some drums and I learned working with computers, samplers, midi controllers - and stuffs.
I usually work with Propellerhead's Reason, my old Oxygen 8 and the Reaper.
... more


text:
Flying Conundrum
Take a break from the drudgery with some of these jokes, song parodies, anecdotes and assorted humor that has been
collected from friends & from websites across the Internet. This humor is light-hearted and sometimes slightly
offensive to the easily-offended, so you are forewarned. I have taken care to censor "humor" with overt sexual
overtones (or undertones) and hateful
tirades, so it is all workplace-safe. I have also tried to warn of any links that will result in audio
clips so you can take appropriate precautions. Please send any potential candidates for this humor
page to the e-mail link above.
Here's a great conundrum sent to me by Steve Swartz. Quiz: This is a true story -- can you guess the answer? My wife, Barbara, and I left on a flight to New Orleans on June 9, from Baltimore Washington International airport. Halfway through the flight I took these photos. Barbara was reading her book and then looked up. No one else was on the plane, so I went to the cockpit and no one was there either! This is not staged. Here are pictures that document this true story. What could have happened?
Custom Search
More than 10,000 searchable pages indexed. Your RF Cafe
single-handedly redefining what an engineering website should be. |


text:
Zack: We might be edging into the 70's on this one. When was the last time people wore fluted vests and pauldrons?
Steve: What time is it right now?
Zack: This game looks more fun than Mech Assault 2, which is a good thing, because that was a pretty fun game.
Zack: For a bitch idiot to play.
Steve: They're not playing a game, bro. This is deadly serious. This is the situation room of the future.
Zack: That would make the guy with the beard Hillary Clinton and I think the woman talking into her giant headset and seemingly holding a pancake house's syrup carafe is Joe Biden.
Steve: Dumping syrup on a Locust sounds like something he'd do.
Hows about you, me, and five uncomfortable minutes in my basement apartment next to the dusty Christmas tree that's still up from my last visit with my estranged children.
The Upper Kitchen Cabinet Where Your Roommate Keeps His Food: You'll 'need the footstool' to reach your roommate's 'fine selection' of 'stale cereal,' but he'll never notice if 'only a little is missing from each box.' Feel less guilty by reminding yourself that Jeff 'acts weird around your girlfriend,' and always 'asks about her.' What a 'creep.'
Take a look back with us at some of the best and worst awful movie moments of the year!
Pictures of cute animals are taking the Internet by storm! (It's a very destructive storm.)
This ain't your daddy's globe...! .... or is it?!
Zack Parsons, Steve "Malak" Sumner, and friends tackle bizarre role playing game products that make them wonder, "What the fuck!?" From the early days of Gygax to contemporary role playing games, none will be spared.
Copyright ©2015 Rich "Lowtax" Kyanka & Something Awful LLC.


text:
follow Dictionary.com
Know how to use "fewer" and "less"? Find out.
1889, "tall hat;" also used synechdochically for men who wear such hats; figurative meaning "swelled head" is from 1923. Drum set sense is from 1934.
(also high-hatty): his high-hat posturings/ high-hatty pretentions (1925+)
: How come you're high-hatting me, old buddy? (1925+)


text:
(Updates with excerpt from filing in third paragraph.)
Jan. 9 (Bloomberg) -- Two Wall Street groups asked a federal appeals court to delay a U.S. Commodity Futures Trading Commission rule that limits commodity speculation, saying the regulation is already imposing "irreversible harms."
The International Swaps and Derivatives Association Inc. and Securities Industry and Financial Markets Association filed an emergency request today in Washington urging a three-judge panel to put the rule on hold while the court considers their legal challenge. The groups asked the court to issue a ruling by Jan. 27.
"The rule will force market participants to forgo efficient trading strategies, impair their ability to hedge against risks, and potentially require them to restructure their businesses," the groups said in the filing. "These costs will mount now absent a stay, and they would be impossible to recoup if the rule is invalidated -- as it likely will be."
The groups, in one of the financial industry's highest- profile efforts to weaken last year's Dodd-Frank law, filed lawsuits challenging the rule in two federal courts in Washington last month.
'Flawed' Analysis
They argue that the CFTC used a flawed analysis of Dodd- Frank when it decided to impose the restrictions. The associations also said the CFTC failed to properly weigh the rule's costs and benefits.
In today's filing with the U.S. Court of Appeals, the groups argue that their challenge will likely succeed, noting that a majority of commissioners concluded the rule was unnecessary and would have rejected it "but for one commissioner's mistaken view that Congress required it."
They said the rule will impose costs on the economy because some companies may not invest in other companies as a way of avoiding the aggregation requirements.
Steven Adamske, a CFTC spokesman, declined to comment on today's filing.
The CFTC, on Jan. 4, asked the appeals court to dismiss the challenge claiming it doesn't have jurisdiction to consider the lawsuit. The agency said that the district court must first consider a challenge to the rule.
Banks, Asset Managers
In response to questions from the district court judge, the groups said last month they didn't oppose putting the district court case on hold while the appeals court considers the challenge.
The groups, in today's filing, said the appeals court has jurisdiction to consider the case.
The two associations represent JPMorgan Chase & Co., Goldman Sachs Group Inc. and Morgan Stanley, among other banks and asset managers.
The rule is among the most controversial provisions of Dodd-Frank, and spurred more than 13,000 public comments to the CFTC from supporters including Delta Air Lines Inc. and opponents such as Barclays Capital. The agency voted 3-2 at an Oct. 18 meeting to approve the final regulation, with Jill E. Sommers and Scott O'Malia, both Republicans, voting in opposition.
The case is International Swaps and Derivatives Association v. CFTC, 11-01491, U.S. Court of Appeals for the District of Columbia (Washington).
--With assistance from Silla Brush in Washington. Editors: Mary Romano, Michael Hytha
To contact the reporter on this story: Tom Schoenberg in Washington at email@example.com.
To contact the editor responsible for this story: Michael Hytha at email@example.com.


text:
58015 Apartments for Rent
Search Apartments in 58015
"You make this whole apartment searching process a lot easier. The way your site is set up helps me search and contact places to find the information I need to make my decision." - Christine,ND
Why Search With MyNewPlace?
- Floor Plans
- Photos
- Interactive Maps
- Videos
Apartment Living in 58015
Finding an apartment in 58015
58015 has great apartment rentals to choose from in a wide variety of different neighborhoods and surrounding cities. You can easily find a pet friendly apartment in 58015 or search for amenities like a fitness center, swimming pool or off-street parking. Make sure that you discover all that 58015 has to offer when looking for an apartment for rent.
Cities Near Christine, ND
There are many great communities and cities nearby Christine, ND to also consider:


text:
Amy Grant to Join Vince Gill
Recent Headlines
It's a dog-eat-dog world at the 2015 Puppy Bowl
It's Ruff versus Tuff in the 11th annual football game of puppy power!
in Music
Miranda Lambert leads Academy of Country Music Award nominees
Miranda Lambert looks set to dominate the ACM Awards after scooping eight nominations.
Nickelodeon latest to offer streaming service
Good news for "SpongeBob SquarePants" fans.
in Sports, Viral Videos
WATCH: 4 unforgettable Super Bowl halftime shows
Four of the most memorable Super Bowl halftime shows ever.
Jeff Bridges hopes his new album puts fans to sleep
"The Big Lebowski" star has released "Sleeping Tapes," a project full of spoken word pieces and meditation mantras.


text:
Webcams may let you stay in touch with friends and family also a webcam allows you to record and stream video from your computer or laptop to the Internet or a video file. When you are not using
WebCam On-Off v1.2
Easy Context menu v1.5
Ntfs Drive protection v1.3
USB Flash Drives helps us to transfer files from desktop to/from laptops or even share its content with our peers. It makes our life easier but If the USB flash drive is infected with virus, not only you may
Ratool v1.2 (Removable Access tool)
Removable Access tool is a very simple-to-use portable freeware Application it helps an individual or a system administrator control USB storage devices , CD-DVD devices, Floppy device , Tape and


text:
Marcus, William Allen and Elliott Clinton Daughterty were brothers who lived with their father John Daugherty in or near Lincoln Co in the mid-1800's. Marcus and William joined the Confederate army in this county. Any information to be shared would be appreciated. Lana Tevis Griffin
Home | Help | About Us | Site Index | Jobs | PRIVACY | Affiliate |
© 2007 The Generations Network |


text: My family of 6 enjoyed renting a pontoon for the afternoon and exploring Sodus Bay. They only have one boat for rent, so it's best to call ahead and reserve it. The staff and owners were friendly and helpful and the boat was in perfect condition. After our afternoon on the water, the kids went to play on the beach... More


text:
Read what other Viator.com travelers think about the New Orleans Original Cocktail Walking Tour. What they loved, what they liked and what they think could be improved, it's all here to help you make the most of your next trip.
Click here for tour details, schedule and pricing
Great tour! So much fun, we can't wait to do it again.
Was tremendous and got so much info from Jo our guide. The best part of our trip to NO!
Very good experience on the Cocktail Walking Tour. Learned a lot about the bars, cocktails, and history of New Orleans. Highly recommend taking this tour early in your trip.
Our guide Joe was the consumate guide. He knew his subject, loved his subject and taught how to appreciate New Orleans and its history. Not a pub crawl but a very informative tour of the historic areas of the French Quarter. He also shared a first person account of Katrina. 5+ stars!!
My wife and I had a fantastic time. It was really cool to go into bars off the beaten path and to get away from Bourbon Street. Our guide was amazing "Sandy Smith". This activity was more than I expected. My wife and I took this trip and thought it would be more like a pub crawl that takes you to the different bars and tells you about some city highlights along the way. How narrow was that thought. This tour is so much more. We learned much history in a short amount of time. Our guide, Joe shared he had been doing this tour for 12 years. He shared great information and managed the group well. There always seems to be a person or two that makes comments or asks strange questions that make you think, really??? We had a couple like that in our group and Joe was professional in either commenting or just moving the tour along. Joe asked if anyone had been on the tour before as there are several historical bars he can take the group to so if there were some that had been on the tour before, he would take the group to other places to make it a different experience. Each historic bar we went to is known for a unique drink. While the drinks are not included in the price and you can decide if you want one or not, it was interesting to hear the history of the drink and/or how it is made. These are bars not on Bourbon Street. Antoine's was a place Joe took us to areas that are not open to the public.
Fascinating history of cocktails and the best place to get a classic Our guide was perfect. This is not a pub crawl, but rather NOLA history with cocktails.
My wife and I had a fantastic time. It was really cool to go into bars off the beaten path and to get away from Bourbon Street. Our guide was amazing "Sandy Smith". If you decide to do the tour you must must must request Sandy Smith. She made the tour!!
Very informative and guide had alot of local knowledge. Was well worth the money.
More then I imagined . I learned more history in 2 hours about New Orleans then my whole life time. The drinks were an added bonus. Needs to be at the top of your checklist when in Mew Orleans
Off the beaten path is definetly the way to go!
This is like a historical tour; it's a history of the bars around the Quarter and the drinks they created (available but not included in the price). Really fun, and tasty. I would do it again.
The tour was great. So informative and fun. We got to see things that we wouldn't on our own. Etienne (sp?) our tour guide was a wealth of knowledge.
Different, entertaining, and full of info. I felt enlightened and a tad drunk.
Guide was very entertaining. I was amazed by some of the drinks!!! Definitely do that one again. And again, really need to clean up the smell in French Quarters...nasty!!


text:
Two and a Half Men Review: "One False Move, Zimbabwe!"
Walden tries to meet Zoe's parents on this week's Two and a Half Men, while we get to meet his mother and brother.
Posted in:
Two and a Half Men
Top Shows
© 2015 TV Fanatic | About Us | Copyright Inquiry | Privacy Policy | Contact Us | TV Fanatic Plus
Sign up for our daily newsletter to receive personalized television news for free!
No thanks. I hate television.


text:
Street Style Pictures of Black-and-White Clothing
15 Street Stylers Prove You Can Never Go Wrong With Black and White
15 Street Stylers Prove You Can Never Go Wrong With Black and White
Here's the thing: the black-and-white color combo isn't going anywhere anytime soon. It's no wonder why glamorous A-listers, the downtown-cool set, and everyone in between gravitate toward this monochromatic dressing palette: it's virtually impossible to get it wrong. The only snag that comes with this classic pairing is breathing new life into it. To keep this quintessential contrast fresh, we've culled an eclectic mix of street stylers in their black-and-white best. From stark graphic prints and strategic LWD colorblocking to old-school denim cutoff and t-shirt match-ups, there's enough styling inspiration to keep our sleek Summer outfits on point. For more monochromatic goodness, just keep clicking.
Black and White
Summer Style
Street Style
Link Love
- Say goodbye to the affordable Kate Spade shop — The Cut
- And the next face of Chanel is . . . — Style.com
- Joe Zee is the king of fashion, but it's not all fun and games — HuffPost Style
- Now you can get your hands on Shay Mitchell's jewelry — SheFinds
- Currently coveting: all of Victoria Beckham's must haves — Who What Wear
- You have to see Sarah Jessica Parker's latest shoe collection — InStyle
- Is there any hope for Coach? — Fashionista
- Dov Charney just can't let American Apparel go — Racked
- Put down the basic blazer — your work wardrobe, revamped — Lucky
Latest Fashion


text:
The leaks are about to happen at any given moment now, usually night time(EST/PDT). EST members are 14 hours behind Tokyo time and PDT members are 17 hours behind. Please keep this thread updated for any leakage of information. In case you don't know what I am talking about: http://gamingeverything.com/35253/famitsu-teases-surprising-metal-gear-solid-news-for-next-issue/
I bet it's gonna be something stupid, like a line of Metal Gear Rising themed t-shirts from Uniqlo or something.
Just a reminder from your friendly neighborhood Four, don't post scans or link to articles which have uploaded scans.
If we can't link to pages with scans, are we allowed to at least say "Hey go to XXX.Com and read the article"?
No, you link to an article that links to an article that links to a tumblr that mentions an instagram that goes to a photobucket that has a screencap of a website that contains an article that links to an email containing the zip file which opens a rar program to open up the ace file containing the scans. Scanception.
Famitsu review scores are being posted so expect the MGS "surprise" announcement to be leaked anytime now. Source: http://gamingeverything.com/35808/famitsu-review-score-121812/
They showed alot of things for Rising in the past week...like ALOT. Don't think it is Rising related. What kind of "surprise" can we expect from Rising anyway? revealing Sunny? Don't think so.
Someone leaked Famitsu's Final Fantasy XIII-3 announcement. Nothing for Metal Gear yet! Something is not right.
XOFRepublic: I would tell you to STFU, but the fact is it can't be liquid. Unless. Unless. Unless. Unless his arm transplant became more and more advanced. So much so that Snake and us couldn't tell the difference at shadow moses. But the terrors of phantom pain were somehow stored within. Ocelot didn't know.
XOFRepublique, you ruined it when you said it was Liquid. Liquid lost his arm post Shadow Moses events which was between 2005-2007. He always had his own arm when he was alive. Secondly, Liquid lost his right arm because that's what Ocelot lost, the trailer shows a left lost limb. Bottom line, it can't be Liquid. UPDATE: Apparently FFXIII-3 was NOT leaked from a Famitsu magazine. It was a different japanese gaming magazine.
Just ask him to find a youtube link and if your bullshit-radar starts going crazy we'll know it's him.
ONE LAYMAN MIGHT INFER, WELL WHAT'S SYMBOLIC THEN ABOUT THAT WHALE? WELL WHALE, THREE WORDS, KASATKA KILLER WHALE, NEED I SAY MORE? THE WHALE IS LENDING DEFINITION TO THE HELICOPTER IT SWALLOWS, AND ONE FAVORITE FOR OCELOT, WHICH IN TURN LENDS DEFINITION TO THE MOST LIKELY INTRUDERS, SOVIETS. WHY IN ANY NATURE WOULD THE RUSSIANS BE ATTACKING OUTER HAVEN? I'LL EXPAIN SOON.... I feel stupid by not catching that. "KA-60 Kasatka; the killer whale." Fucking DUH!!!!!!!
Nothing..yet. Magazine is officially out on Thursday. Apparently no one wanted to leak the info or maybe today.
See this thread on the front page. 44 replies. Can't wait for the new MGS info. It's just some guy talking rubbish in capital letters. Nevermind
It is coming. The magazine is officially out in Japan on Thursday. It's 4:10AM now in Japan. Hopefully within the next 5-8 hours someone from Japan shares the MGS section.
The magazine comes out on Thursday which is now in Japan(11:16pm). Someone needs to pick up the mag and share the Metal Gear bits.
This is odd I don't see a single page about the Famitsu magazine in Japanese or English and I can't find anything related to MGS I don't think anyone has got it up on the internet is my bet. And hopefully this magazine isn't anything about MGR. tomorrow morning or afternoon, expect then.


text:
This apartment could not be better located, looking out over the Colosseum and Foro Romano in the heart of the old Roman city centre. The Colosseum, opened in 80 AD, is perhaps the most iconic sight of Rome. The Foro Romano is equally impressive, considered the oldest part of the city and home to several important Government buildings dating from the height of the Roman Empire.
This charming and colourful apartment is situated in a traditional Rome building recently renovated to the highest standards, combining stylish design and elegant décor. The living room is bright and spacious with large windows, wooden floors and high ceilings. The room is furnished with a double sofa-bed, armchairs, a desk with chair and a flat screen TV. The kitchen is fully equipped with everything needed to prepare meals, including a microwave, hob, fridge and freezer. The kitchen also features a small dining table.
The bedroom is bright and spacious, with a double bed, elegant lamps and plenty of closet space.
The neighbourhood is a typical Rome neighbourhood and exploring the streets around the apartment will reward you with the discovery of great restaurants, boutique shops, great food, hidden churches and other memorable public spaces. The Colosseum, opened in 80 AD, is perhaps the most iconic of sight of Rome. For close to 2000 years the Amphitheatre has captured the hearts and minds of locals and tourists alike and is often considered one of the greatest works of Roman architecture and engineering. The Foro Romano is equally impressive, considered the oldest part of the city and home to several important Government buildings dating from the height of the Roman Empire. Spending a few hours walking around the Forum gives you an idea of the just how impressive the city would have been 2000 years ago. Within walking distance of the apartment are other major Rome attractions including the stunning Trevi Fountain, one of the largest fountains in Rome. This stunning fountain stands 26 metres high and 20 metres wide and it is said that visitors should throw a coin into the fountain to ensure a return to Rome in the future. Just a few hundred metres from the Trevi fountain are the Spanish Steps, the widest steps in Europe and something that must be visited on any trip to the city. From the bottom of the steps make your way to Piazza del Popolo, Northern Rome's biggest piazza complete with an obelisk, lion sculptures, churches and a beautiful garden located just above. Walking around this amazing city you will be confronted with historic sights on every corner and this apartment is in the ideal location to do just that.Check-in: | From 15:00 Check-out: Until 11:00 |
Payment: |
Visa, MasterCard Note: the hotel can pre-authorize your card before arrival; they check for sufficient funds in order to guarantee your booking. |
Internet: | Wi-Fi Internet free of charge in all rooms and general areas (lobby/reception etc.) |
Parking: | Public parking |
Pet policy: | Pets allowed Free of charge |
Rooms: | 1 |
General facilities: |
Extra common areas: |
Important information & conditions: |
Please note that a non-refundable deposit will be charged on the given credit card and the remaining balance will have to be paid in cash at the time of check-in. The keys will be handed once the total amount of the reservation is paid. |
Note: It is the responsibility of the hotel chain and/or the individual property to ensure the accuracy of the photos displayed. We are not responsible for any inaccuracies in the photos. | |
Please provide this reference number to our customer service center representative on request, so we can help you better


text:
From Wikipedia, the free encyclopedia
Esser is a surname. Notable people with the surname include:
- Esser (musician), English musician born Ben Esser
- Clarence Esser (1921–2009), American football player
- Dave Esser (born 1957), English footballer
- Dick Esser (1918–1979), Dutch field hockey player
- Dragutin Esser, French racing driver
- Franz Esser (1900–1982), German footballer
- George Esser (died 2006), American civil rights activist
- Hans Esser, German fencer
- Heinrich Esser (1818–1872), German classical violinist, composer and conductor
- Hermann Esser (1900–1981), German Nazi leader
- Irene Esser (born 1991), Venezuelan beauty pageant winner
- Jan F. Esser (1877–1946), Dutch plastic surgeon
- Janice Ferri Esser, American television writer
- Leo Esser (born 1907), German diver
- Luke Esser, American politician
- Mark Esser (born 1956), American baseball player
- Markus Esser (born 1980), German hammer thrower
- Michael Esser (born 1987), German footballer
- Patrick J. Esser, American businessman
- Paul Esser (1913–1988), German actor and voice actor
- Piet Esser (1914–2004), Dutch sculptor
- Robin Esser (born 1935), English newspaper executive and editor
- Roswitha Esser (born 1941), West German sprint canoeist
- Walter Esser (born 1945), German modern pentathlete
See also[edit]
- Esser Hill, mountain in Victoria Land, Antarctica
- Esser Bluff, cliff on Ross Island, Antarctica
This page or section lists people with the surname Esser. If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link. |


text:
ROCHESTER, Minn. and WASHINGTON -- The world's first and largest group medical practice and one of the nation's premier volunteer service organizations of professional African American women are joining forces to eradicate health disparities among communities of color in the United States. Mayo Clinic and The Links, Incorporated have established a formal collaboration that aims to develop a more diverse health care workforce. The joint initiative ranges from raising health awareness in the African American community to facilitating scientific research -- with a special focus on cardiovascular disease, cancer, organ transplantation and obesity. The collaboration stems from one patient's experience.
Ginger Wilson, a Chicago lawyer and businesswoman, had been experiencing breathing problems -- wheezing, shortness of breath -- as well as weight loss, inflammation and digestive issues.
"After 18 months, I had been diagnosed with asthma, an intestinal bug, an ulcer, rosacea and more," she says. "I received treatment for the individual symptoms, but never one diagnosis for all the symptoms."
One day, while on an outing, Wilson found she couldn't hike more than a few hundred yards. A friend, who was a doctor in training at Mayo Clinic, asked if she'd been checked for carcinoid syndrome, a condition caused by secretions from a slow-growing tumor. Wilson traveled to Mayo Clinic for evaluation, where the diagnosis was confirmed and she underwent treatment. Seven surgeries later, she is back to being active in her Chicago community and owns the first African American female legal staffing firm.
Wilson shared her experience with her friends at Mayo and The Links, Incorporated. Conversations occurred, connections were made and pilot projects developed. To date, educational forums have been held with Mayo Clinic physicians and Links chapters in Chicago and Atlanta. Public service announcements have been produced, and research findings
Contact: Bob Nellis firstname.lastname@example.com 507-284-5005 Mayo Clinic Source:Eurekalert |


text:
This site uses cookies to improve your user experience.
Click View Hotel(s) button to view. Otherwise, continue to Check Availability
Please specify any room allocation details and requirements below
For those travelling to the hotel by car there is free parking on-site for 300 cars.
in Aberdeen °C or °F
31 Jan Sat
01 Feb Sun
02 Feb Mon
03 Feb Tue


text:
Schedule TBA
©2015 Belle-Clair Speedway All rights reserved
At the ripe young age of just 23, Trey Marcham is working hard to accomplish what hopes to be a racing career someday. With over 12 years of racing experience, Trey, from Newcastle, Oklahoma, will be competing in four different venues of racing on 18 different tracks in 10 different states. Trey will be running NASCAR late models on asphalt on the east coast, minisprints, midgets and outlaw cars in the center of the country, and midgets on the west coast. A valedictorian at Newcastle High School, currently attending the University of Oklahoma full time studying mechanical engineering, Trey stays pretty busy. Spending almost all his free time racing or working on his cars, he has collected quite an array of achievements over the past eleven years he has been racing.
2014 Honda USAC-Western States Midget A Feature Winner twice at Bakersfield Speedway and once at Tulare 2013 Honda Western MIdgets Rookie of the Year 2013 Myrtle Beach Raceway back-to-back Late Model A Feature wins 2013 BCRA Midget A Feature Winner Petaluma Raceway 2013 Ryan Craighead Memorial A-Class Friday night A-Feature Winner, I44 Riverside Speedway 2012 Donnie Ray Crawford Memorial/Race4Life A-Class Winner and Non-wing Winner, Port City Raceway, Tulsa, OK 2012 Newport Speedway NASCAR Late Model UARA Series Rookie of the Race/2nd Place finish, Newport, TN 2012 Hickory Motor Speedway NASCAR Late Model UARA Series Holley Performer of the Race, Newton, NC 2012 66 Mike Phillips Memorial Race Outlaw Class Hard Charger Award, Southern Illinois Raceway, Marion Il 2011 I44 Speedway A-Class Track Champion and Non-wing Track Champion, I44 Speedway, Newcastle, OK 2011 Ryan Craighead Memorial Non-wing Preliminary Night A Feature win
No news found at this time
MyRacePassTM is your ticket to the online motorsports world. Tired of having to remember your username and password for countless different racing websites? MRP is a globally recognized login across a vast network of motorsports websites (including this site). Having your "MyRacePass" account will handle your username, password, profile picture, and all account information for any website on the network. You will be notified of updates to the network as it continues to grow. We thank you for being a part of this ground-breaking motorsports online experience.


text:
The finest pregnancy nutrition should incorporate plenty of high fiber low fat whole foods for a sound, balanced diet. Expecting mothers need to monitor their nutritional needs carefully. While researching healthy pregnancy nutrition , understand that it is healthier to consume vitamins, minerals and other nutrients that are attached to whole foods, not isolated supplements. The body absorbs nutrients from whole foods most effectively, whereas isolated vitamins and minerals are often flushed out before the body can put them to use for fuel.
Calcium is a valuable mineral for flawless pregnancy nutrition. Nonetheless, it is challenging to get a sufficient amount of calcium from whole foods like fruits and vegetables. Some of the more common sources of calcium are broccoli, yogurt, cheese, milk, and beans. For those inclined to take a calcium supplement , not only is it critical for pregnancy nutrition that the calcium originates from whole foods, it is equally important that Vitamin D2 is present. Vitamin D2 is important to aid the body in absorbing calcium and is a required component for improved bone strength and density. Folate, also called Folic Acid and Vitamin B9 is another critical nutrient for complete pregnancy nutrition. Folic acid is a B vitamin that helps the body to generate healthy new cells. That is why folate is very important for pregnancy nutrition as hopeful mothers create new life. Moms who add plenty of folic acid in their diets are doing the right things toward preventing birth defects. For accurate pregnancy nutrition, a woman needs around 800 mcg of folic acid daily. Nursing mothers only require about 500 mcg. This benchmark may not be easy for some to achieve, as it requires up to six servings of whole foods such as leafy green vegetables, broccoli, or beans, every day. If a pregnant woman is not getting enough folate from whole foods, then whole food vitamins or supplements should be investigated. |
Write a comment:


text:
Updated 11/06/2014
This high-volume hotel is at the south end of long and lovely Bucerías Beach and has manicured grounds and a pool for each of its six buildings. Rooms are plain and not particularly modern, with laminate bathroom counters and cheap doors. But that's a small price to pay for the excellent beachfront location and astoundingly low all-inclusive prices. Rooms in the older section have the best views, since they were built along the water; rooms on the other side of the road
have the benefit of being adults-only and are almost brand new. Besides location, the only real distinction between one room and another is whether the room has a king or two double beds. The median age of the clientele here is around 50 years old.
329-298–0226; 01800-011–1111
Website: www.decameron.com
Hotel Details:
Updated 11/06/2014


text:
Bishop Ford Freeway
Cyclist Struck, Killed By Semi On I-80/94 Entrance Ramp
Illinois State Police said the cyclist appeared to be riding onto the Torrence Avenue entrance ramp onto the eastbound lanes of the Bishop Ford Freeway around 5:15 a.m., when a tanker truck struck him.
Man Critically Injured In Fiery Crash On Bishop Ford
Charges are pending against the driver who state police say caused a fiery three-car accident on the Bishop Ford Freeway that left one man critically injured late Tuesday in south suburban Dolton.
Woman Killed When Tire Smashes Into Windshield On Bishop Ford
A 64-year-old woman was killed Wednesday morning, when a tire flew off an SUV on the Bishop Ford Freeway, and smashed into the windshield of her car.
Man Killed In Crash On Bishop Ford
He was driving a motorcycle that struck another vehicle.
Jackknifed Semi Blocks Lanes On Bishop Ford Freeway
The accident, which occurred about 5:15 a.m., blocked one southbound and two northbound lanes, according to Illinois State Police.
Crash On Bishop Ford Injures 6, Closes Southbound Lanes
Six people were injured in a traffic crash involving two semi-trucks and a passenger vehicle on the Bishop Ford Freeway early Tuesday, prompting authorities to close the interstate's southbound lanes to travel.
Woman Dies After Falling Out Of SUV, Being Hit By Semi On Bishop Ford
Jennifer Mitchell, 27, was struck sometime before 1 a.m. near 154th Street by at least two vehicles, authorities said.
2 Men Shot In Bishop Ford Freeway Drive-By
The Bishop Ford Freeway was shut down for hours Saturday morning, as Illinois State Police investigated a shooting.
Three Females Hurt In Bishop Ford Crash
Three females were hurt in a two-vehicle rollover crash early Sunday that led to two related wrecks on the Bishop Ford Freeway (I-94).
Man Killed, 2 Women Injured In Crash On Bishop Ford Exit Ramp
A man was killed and two women were injured early Monday in a crash on an exit ramp from the Bishop Ford Freeway.
1 Dead, 1 Wounded In Bishop Ford Crash
One motorist is dead and one other is wounded after a two-vehicle crash early Sunday on the Bishop Ford Freeway where alcohol is believed to be a factor, state police said.
Man Driving To Work Killed By Wrong-Way Driver On Bishop Ford
A motorist on his way to his job at the Chicago Tribune was killed early Monday when a wrong-way driver collided with his vehicle on the Bishop Ford Freeway.
Truck Runs Over Car, Causes Pileup On Bishop Ford
A car was essentially run over by a semi-trailer truck on the Bishop Ford Freeway early Wednesday, causing a pileup and a major traffic jam.
Shots Fired At Nightclubbers On Bishop Ford, Driver Wounded
A motorist was shot while driving on the Bishop Ford Freeway early Sunday on the Far South Side.
Dump Truck Accident Snags Bishop Ford Freeway
Traffic jams mounted on the Bishop Ford Freeway Tuesday morning, when a dump truck slammed into a divider wall and left a lane blocked.
Mystery Surrounds Deadly Bishop Ford Crash
As investigators try to get to the bottom of a deadly weekend accident on the Bishop Ford Freeway, one major question remains.
3 Killed In Crash On Bishop Ford Freeway
A woman, her son and another man were killed Sunday morning when their car was rear-ended by an SUV while they were stopped in the center lane of the Bishop Ford Freeway.
Police Vehicle Bursts Into Flames On Bishop Ford
An investigation is underway after a Chicago Police vehicle went up in flames overnight on the Bishop Ford Freeway.
Man Found Dead On Bishop Ford Exit Ramp
A man's body was found Thursday afternoon on a Bishop Ford Freeway ramp on the Far South Side.
Man Killed In Bishop Ford Crash
Police say an Evergreen Park man fell asleep at the wheel on the Bishop Ford Freeway, and it cost him his life.


text:
Where the lives of the cats you followed in the books become the real thing; and so much more! Everyone is welcome here, so join in the fun today!
free, forum, warriorclan, warriors, erin, hunter, roleplay, warrior, cats, tribe, role, play, written, #clans
An immersive, active role-play website based on the "Warriors" series by Erin Hunter, though the characters are wolves.
four, #clans, immersive, active, role-play, website, based, "warriors", series, erin, hunter, though, characters, wolves
Come join the one of the best Call of Duty communities/clans there is! We are active and still going strong after a whole year!
Four clans, four different lives. Which path will you take? Your choice, could be deadly..
A place to discuss strategy, rules, bases, recruitment, promotions etc between the 2 clans.
gold, squad, pyrite, clash, #clans, base, troops, strategy, clan
Sisters both who was born as vampires was broken apart because of rage. Now seperated they formed two clans one of darkness the other of light. Will you choose one?
shadowed, intells, sisters, both, born, vampires, broken, apart, because, rage, seperated, they, formed, #clans, darkness, other, light, will, choose, one?
The world in our paws is a warrior cats RPG based off of Erin hunters Warriors series. Play in one of the four clans (Thunderclan Riverclan Shadowclan Windclan).
world, paws, warrior, cats, based, erin, hunters, warriors, series, play, #clans, (thunderclan, riverclan, shadowclan, windclan)
A meeting place for the members of Iowa Clan!
3 clans, 2 good and one evil. What happens when evil tries to unbalance the scale of good and evil ?
free, forum, warrior, cats, evil, good, role-play, warriorcats, #clans, leaders, deputies, goodclan, evilclan, fight, warriorcatsforum, catforum, clanforum, activeforum, roleplayforum


text:
January 29, 2015, 06:36 pm
Kerry cited for not shoveling snow
By Jesse Byrnes
The secretary of state will gladly pay the ticket, a spokesperson said.
January 29, 2015, 06:36 pm
By Jesse Byrnes
The secretary of state will gladly pay the ticket, a spokesperson said.
January 29, 2015, 06:19 pm
By Jonathan Easley
He tweeted a fake phone call between two actors dinging his potential 2016 rivals.
January 29, 2015, 05:36 pm
By Peter Sullivan
The trips could open Clinton to attacks.
January 29, 2015, 02:56 pm
By Jonathan Easley
David Kochel, who headed Romney's past Iowa efforts, is in line to manage Bush's campaign.
January 29, 2015, 01:42 pm
By Peter Sullivan
The Vermont senator is considering a challenge to Clinton from the left.
January 29, 2015, 12:00 pm
By Ben Kamisar
He's launching the "Security through Strength" committee as he weighs a White House bid.
January 29, 2015, 10:29 am
By Ben Kamisar
The "First in the Nation Republican Leadership Summit" will be held April 17-18.
January 29, 2015, 09:40 am
In a radio interview, the Wisconsin governor shakes off criticism that he lacks charisma.
January 29, 2015, 08:18 am
By David McCabe
Clinton is reportedly considering rescheduling an announcement until the summer.
January 28, 2015, 05:53 pm
By Jonathan Easley
Indiana governor and potential GOP 2016 contender says the reports caught him by surprise.
The Hill 1625 K Street, NW Suite 900 Washington DC 20006 | 202-628-8500 tel | 202-628-8503 fax
The contents of this site are ©2015 Capitol Hill Publishing Corp., a subsidiary of News Communications, Inc.


text:
Choose Sport: Choose Region:
Apr. 20, 2012: Watch highlights from Hicksville's (black) 8-7 boys lacrosse victory over Port Washington (white).
Gregg Sarra and Carl Reuter break down the Long Island Championship games and discuss the Nassau County Awards Dinner.
Gregg Sarra and Carl Reuter discuss the fall's top student athletes, while Andy Slawson stops in to discuss Long Island wrestling.
Join Carl Reuter and Nick Garone as they discuss the Eastern National Championships, wrestlers to watch for in 2012-13 and talk to Rocky Point head coach Darren Goldstein.


text:
Bomb Attack On London
0Jul 7, '05 by Silverdragon102, RN Adminbomb attack x 7 in London (6 x tube stations and 1 bus)
My thoughts and wishes go with everyone in London and any visitors to the country caught up in the blasts -
0Jul 7, '05 by PeachyOrthoRNMy heart goes to everyone that was injured. I'll be praying for them all.
0Jul 7, '05 by jnette GuideBeen up watching the news on this since 0630... simply horrible. Certainly our hearts are with all of you in this devastating tragedy. Will be keeping our eyes on this situation for the remainder of the day.. and weeks to come.
Please stay safe, and sincerely hope that none of our British Allnurses friends have been personally affected in any way.. may their loved ones all be well.
(((HUGS))) to all of you.


text:
Offers for Toyota Land Cruiser 4.2 TD Automatic
Ask a question Write your own review Write a review and you will earn 0.5p per rating if other members rate your review at least helpful.
Receive review alert for this product
Comment on this review
Add review to Favourites
Print review
Upload video review
Add to my Circle of Trust
Subscribe to reviews
About me:
Member since:01.01.1970
Video reviews:1
Advantages: all of them
Disadvantages: eat petrol but who cares?
Recommendable Yes:
Detailed rating:
Value for Money
Road Handling
Fuel consumption
View all ratings
The overall rating of a review is different from a simple average of all individual ratings.
I love that car. ever since i bought it 6 months ago i promissed myself not to change cars ever again.i'll sell it only if i'm buying a new land cruiser.this is the car every house hold should have!
my next trip is going to be with the land cruiser to the deserts of morroco (sahara), to stay there for 2 weeks and survive like bear gryls from "born survivor", eating the best cuscus in the world and checkinghow it is to live on mountain tops.
Share this review on
« Previous review Next review »
Rate this review »
How helpful would this review be to a person making a buying decision? Rating guidelines
Rate as exceptional
This action can only be made by logged in members.
The review covers all aspects of the product and its user-friendliness which would be relevant to making a product choice. All remarks are founded on evidence from personal experience and the author remains objective throughout. A reader could find sufficient information here to base his/her purchase decision on this review alone.
Rate as somewhat helpful
The review is not always objective or founded on evidence from the author's experience. The presentation and structure are unclear.
Rate as very helpful
The review covers a wide range of product features and the author's position is clearly-explained, well-structured and founded, for the most part, on solid evidence. This review would be of great use to somebody making a product choice, but would have to be used in conjunction with other information sources.
Rate as not helpful
The review is not a helpful decision-making aid. The information it provides is subjective and lacks foundation. Perhaps the content contains comments which do not relate to the product and may be offensive to other members.
Rate as helpful
The review is accurate and clear. The author may not provide complete information but what (s)he does say is useful. The review would give readers an idea of the quality of the product.
Rate as off topic
Reviews relating to products in other categories, or those which stray onto unrelated subjects should be rated "off topic". This will let other readers know that they need not read the review when seeking information that would be useful in a purchase decision.
Write your own review Write a review and you will earn 0.5p per rating if other members rate your review at least helpful. Report a problem with this reviews content
Comments about this review »
blackmagicstar4 20.11.2008 11:02
Great review, sounds nice i like it in red xx
suehome 19.11.2008 23:32
Sure looks a mean beastie..........Sue
The photos have come out well. Eden is a cutie xx
Add your comment
max. 2000 characters
Maximum number of characters reached
Post comment
Car battery 12V 95Ah for Toyota Land Cruiser 100 (Diesel) 4.2 TD (HDJ100) 01/1998 -
By Battery. FULMEN batteries are manufactured by EXIDE and this battery is equivalent to ... more
Car battery 12V 95Ah for Toyota Land Cruiser 90 (Diesel) 4.2 TD 08/1999 - 08/2001
Car battery 12V 70Ah for Toyota Land Cruiser 80 (Diesel) 4.2 TD (HDJ80) 01/1990 - 12/1997
Show all 14 similar offers
Product Information »
Manufacturer's product description
Product details
Show all Product Information
More reviews »
A masterpiece in its class
very helpful
The God of all 4*4
somewhat helpful
Land Cruser
Review Ratings »
This review of Toyota Land Cruiser 4.2 TD Automatic has been rated:
"helpful" by (93%):
and 11 other members
"somewhat helpful" by (7%):
Products you might be interested in »
Toyota Celica 1.8
Hatchback, Coupe - Front (FWD) - 6 Speed Manual Gearbox - 1794, 1796 cc - Max Speed: 127, 140 mph - 140, 189 bhp - Petrol - Available Trims: S, Style, Red, Premium Red, Premium, Blue, T Sport, GT
User reviews (32)
Buy Now
Toyota Yaris 1.3
Hatchback - Front (FWD) - 5 Speed Manual Gearbox, 4 Speed Automatic, 5 Speed Manual - 1298 cc - Max Speed: 109 mph - 86 bhp - Petrol - Available Trims: TR, T3, T Spirit, Colour Collection, Blue
User reviews (42)
Toyota Yaris 1.0
Hatchback - Front (FWD) - 5 Speed Manual Gearbox, MMT Automatic, 5 Speed Manual - 998 cc - Max Speed: 96 mph - 64 bhp - Petrol - Available Trims: TR, T3, T2, T Spirit, Colour Collection, Blue
User reviews (61)


text:
Obituary & Guest Book Preview for Olive Louise Evans Gettys
Olive Louise Evans Gettys Obituary
Published in The State on Nov. 5, 2013
First 25 of 312 words
: Louise Gettys WEST COLUMBIA - A graveside service to celebrate the life of Olive Louise Evans Gettys, 96, of West Columbia, SC, will be held...
View Full Obituary & Guest Book for Olive Gettys
Olive Gettys Guest Book | View 2 of 2 Entries:
View Full Obituary & Guest Book for Olive Gettys
Ways to View
Restore Obituary & Guest Book
Keep the Obituary and Guest Book online for one of these time periods:
Permanent Sponsorship
$ 79.99
One-Year Sponsorship
$ 29.99
24-Hour Restoration
$ 2.95
Print Obituary & Guest Book
Order a professionally printed copy, starting at $39.00:
Deluxe Hardcover Book
$ 79.00
Laminated Hardcover Book
$ 59.00
Laminated Softcover Book
$ 39.00
Didn't find the Obituary you were looking for?
Return to today's Obituaries for the The State.
Powered By
Search Obituaries
How To
Questions? Contact Us
Privacy Policy
© 2015 Legacy.com All Rights Reserved


text:
Total Time:
Prep Time:
Cook Time:
35 mins
15 mins
20 mins
Krystal-Belle's Note:
My husband is an empanada freak, and his mom used to make them occasionally, but not often enough for his liking. Once we got together and he tried mine, he fell in love all over again and now has me making these at least once or twice a month. My son thinks these are fantastic too and they are big enough to fill him up at dinner time with just one or two.
My Private Note
Serves: 5
Units: US | Metric
- 1 lb lean ground beef
- 1 -2 tablespoon Lawry's Seasoned Salt
- 1/2 small onion, chopped fine
- 1/2 teaspoon minced fresh garlic
- sofrito sauce
- 1 dash black pepper
- 15 discos (turnover pastry dough , in the frozen pastry dough or ethnic frozen foods aisle)
- water (to seal edges of pastry)
- oil (for frying)
- 1In a large frying pan on medium heat, brown ground beef, adding in seasoned salt, onion, garlic, and pepper. When meat is browned, drain and put into a bowl. To this, add chopped olives and sofrito until the mixture is somewhat wet, but not runny (it should be about the consistency of taco meat).
- 2Lay discos out on a flat surface and fill the centers with about 1 1/2 tbsp of meat mixture. Use a little bit of water on your finger to go around the edges of the pastry, then fold the dough over and press the edges down with a fork (the water helps the edges to stick and stay sealed). Poke the empanada with a fork in the center so that it does not over-inflate when frying.
- 3Place the empanadas in a deep fryer for about 6-7 minutes or until medium-brown on both sides, then drain on paper towels.
Nutritional Facts for Empanadas...mmm...
Serving Size: 1 (98 g)
Servings Per Recipe: 5
- Amount Per Serving
- % Daily Value
- Calories 163.1
- Calories from Fat 81
- 50%
- Total Fat 9.0 g
- 13%
- Saturated Fat 3.6 g
- 18%
- Cholesterol 58.9 mg
- 19%
- Sodium 60.1 mg
- 2%
- Total Carbohydrate 0.8 g
- 0%
- Dietary Fiber 0.1 g
- 0%
- Sugars 0.3 g
- 1%
- Protein 18.2 g
- 36%
The following items or measurements are not included:
Lawry's Seasoned Salt
Ideas from Food.com


text:
Already a Bloomberg.com user?
Sign in with the same account.
Don't have an account? Sign up.
Help! I can't access my account.
Feb. 21 (Bloomberg) -- Rafi Mohammed, founder at Culture of Profit, discusses the business plan of Uber and complaints of price gouging on Bloomberg Television's "Bloomberg Surveillance."
On Air Now
Davos 2015: Unpegged Watch Now
Inside LEGO
©2015 Bloomberg L.P. All Rights Reserved. Made in NYC Ad Choices


text:
Avanti Productions & Management Ltd.
film & theatre production company talent & literary management
MIHAI ARSENE cast as Stalin's right hand man, the "Iron Commissar" HERCULES SATINOV
Posted by AVAnti Productions on December 14, 2014 at 1:45 PM | comments (0) |
AVANTI P&M is very pleased to announce that our one of a kind actor MIHAI ARSENE
has been cast as Stalin's right hand man, the "Iron Commissar" Hercules Satinov,
in the short film "FATAL ROMANTICS",
inspired by the Simon Sebag Montefiori's "One Night in Winter" novel,
written and directed by Resul Keech.
STEPHANIE HAZEL cast in ROCK BOTTOM
Posted by AVAnti Productions on December 14, 2014 at 12:55 PM | comments (0) |
AVANTI P&M is very pleased to announce that our wonderful English rose STEPHANIE HAZEL,
after taking the vows of marriage earlier this autumn and making a new start in Gloucester,
has now been cast in ROCK BOTTOM short film,
written and directed by Johnny Engelmann, and producer by Tony Stubbs and The University of Gloucestershire.
Stephanie is inheriting the role of Sophie, a 16 years old girl from the West Country
who is trying to break the news to her parents that she is pregnant.
ALLEN WATTS cast in a new REED commercial
Posted by AVAnti Productions on October 27, 2014 at 8:00 PM | comments (0) |
AVANTI P&M is happy to announce that our actor ALLEN WATTS has been cast in a new commercial for REED.CO.UK, directed by Robert Panners and produced by Chloe Misson from Cloud Burst Productions Ltd. Our wonderful actor ALLEN WATTS will inherit the role of Jonny (a Mafia boss Assistant).
The new REED.CO.UK aims to air in two weeks time on internet.
ALLEN WATTS cast in new Channel 5 series FIRST KILL LAST KILL
Posted by AVAnti Productions on October 18, 2014 at 12:10 PM | comments (0) |
AVANTI P&M is very pleased to announce that our summer addition to the agency, actor ALLEN WATTS has been cast in a new Channel 5 series FIRST KILL LAST KILL,directed by Nick Aarons and produced by Crackit Productions. ALLEN WATTS will inherit the role of Harold Mackay, the father of Patrick Mackay who was a serial killer back in the 70s.
FIRST KILL LAST KILL is a documentary type series,
Commissioned as a six part series after the success of the Stockwell Strangler, with the help of leading experts, Prof. Wilson will examine this first kill in frighteningly forensic detail to get deep inside the mind of serial killers. He will walk in the murderers footsteps to understand how an unhinged member of society transforms into a violent and brutal slayer of innocent victims. What did they learn from their first kill and how did they apply it to their next? Then using the first and last kill to drive the narrative he'll forensically examine how our subject evolved from first time murderer to sophisticated serial killer throughout their killing spree, before pulling apart the details of the last grizzly slaying that led to their capture and subsequent demise. What was it about this last kill that led to their undoing? By comparing the first and last kill we'll bring fascinating and intelligent new insight into the life and mind of some of Britain's most notorious killers.
LAKEISHA LYNCH-STEVENS performing at BUSH THEATRE with I AM
Posted by AVAnti Productions on October 12, 2014 at 1:00 PM | comments (0) |
After a successful short run at Battersea Arts Centre, the new SPID experimental theatre show I AM has obtained funds for a UK tour, as well as a full run in London at BUSH THEATRE. With this ocassion, AVANTI P&M is very pleased to announce that our wonderful young actress LAKEISHA LYNCH-STEVENS is currently performing at BUSH THEATRE between 30th September - 25th October 2014.
I think, therefore…iAm
SILVIA BUSUIOC cast in the upcoming feature "UNTITLED"
Posted by AVAnti Productions on October 12, 2014 at 12:45 PM | comments (0) |
AVANTI P&M is very happy to announce that our lead Italian actress SILVIA BUSUIOC has been cast in the upcoming feature
directed by Chris Loizou and produced by Mike Capon and Truk Films.
Our wonderful polyglot actress wil inherit the role of KITTEN,
a beautiful Eastern European girl trafficked in the UK by a merciless man, now with thoughts of becoming a film producer...
Synopsis: "On the verge of his biggest deal yet, indie film producer Kurt Lovell is stuck in his office killing time waiting for the 6pm call that will change his life. As the hours tick by, via phone, email, Face Time, Skype and text, we get to meet the people who inhabit Kurt's world, including his unhappy wife, an obsessive writer, a drug dealing investor, the actress he has had an affair with, and his agent. But life begins to imitate art and events start to spiral out of control until Kurt is not quite sure what is or isn't part of his reality. "
CATALINA MIHAI performing as Lead in Daddies Don't Cry
Posted by AVAnti Productions on October 7, 2014 at 1:40 PM | comments (0) |
AVANTI P&M is very pleased to announce that our youngest Eastern European actress
CATALINA MIHAI will be performing as Anna (Lead) in a new show entitled DADDIES DON'T CRY,
written by Nikos Sarafianos and Margarita G. Pita, directed by Margarita G. Pita and produced by Aight Theatre Collective.
Why do children need both parents after divorce? A true story that starts in every part of the world is unfolding in London. Based on testimonies of parental alienation around the world, Daddies don't cry is a bold performance research project that brings forward the small/big crimes that happen inside broken families.
Sunday 19th October 2014 - 5.30pm
47/49 Tanner Street Arts Space
GEOFFREY CARD on tour in Dubai with The Gingerbread Man
Posted by AVAnti Productions on September 27, 2014 at 5:05 PM | comments (0) |
AVANTI P&M is very happy to announce that our actor GEOFFREY CARD is going on tour in Dubai with
THE GINGERBREAD MAN is directed by Lori Dorman and produced by Lollipop Theatre Company. Our actor GEOFFREY CARD is inheriting the part of PAT the Cow. The tour will be between 12th October - 18th December 2014.
Short Summary: "It's Christmas time! And Alberto the Baker along with his friend Pastry the Cat make gingerbread men biscuits for their customers, but first, they make one great big gingerbread man for themselves as a treat. After a comical misunderstanding listening to the instructions on their Radio, they do eventually succeed in making a giant Gingerbread Man, but suddenly, he comes alive, much to the surprise of Alberto and Pastry. He escapes, Alberto and Pastry want to capture and eat the gingerbread man so they run after him. The Gingerbread manages to hide from there pursuit but he encounters more dangers during his escape, Cow Pat (from Jack and The Beanstalk – The Most famous Cow in history according to….himself!! , Wonky Donkey (a limping, 3 legged, grunting one eyed donkey) and a Fox who is charming but devious hunter, none of whom can be trusted! All of them want to eat the Gingerbread Man! They all catch up with The Gingerbread Man but they all agree that what they are doing is wrong and that this is in fact The Gingerbread Man's story and that he alone should decide how the story should end. The Gingerbread Man decides' they all should become friends, The Gingerbread Man says they can come and see Alberto for food any time they like and they can all visit each other at any time.
They all live happily ever after."
With songs, puppetry, audience participation, slapstick and laughter galore, The Gingerbread Man is a fun family Christmas treat for everyone.
JOSHUA PLUMMER on tour with Rainbow Theatre Company
Posted by AVAnti Productions on August 31, 2014 at 3:05 PM | comments (0) |
AVANTI P&M is very pleased to announce that our young actor JOSHUA PLUMMER is currently in rehearsals and will be touring schools in London and the South East between September - December 2014 with Rainbow Theatre Company.
The Company will be peforming six history based workshops and one pantomine throughout the tour:
"Victorian Children", "The Great Fire of London", "A Child in Ancient Greece", "We'll Meet Again", "A Child in Roman Britain", "Moses & the Egyptians" and "Sleeping Beauty".
To keep up with Rainbow Theatre's touring schedule, please visite their website at:
LUING ANDREWS cast in DARK SIGNAL (2015)
Posted by AVAnti Productions on August 31, 2014 at 1:25 PM | comments (0) |
AVANTI P&M is very pleased to announce that our wonderful actor LUING ANDREWS has been cast in the upcoming feature film DARK SIGNAL (2015), inheriting the role of a tough Bailiff. Dark Signal is written and directed by Edwards Evers-Swindell, with co-writer Antony Jones and starts filming this early September.
Logline: The spirit of a murdered girl returns with a message. Now a stranded woman must team up with the staff of a local station to solve the mystery of her death.


text:
Driven by Drought
BY Nichole Sobecki | Jul. 15, 2011 | 3:13
Having already suffered years of war, many Somalians are now fleeing the most severe drought the region has known in 60 years.
PlaylistUp Next in Africa
← Previous Next →
- Now Playing
International 3:12
A Tragic Choice: Fight Malaria or Starve
Now PlayingOpinion 6:35
An African's Message for America
- Now Playing
Ebola Outbreak 3:16
The Path of the Ebola Outbreak
- Now Playing
Ebola Outbreak 4:03
In Ebola Outbreak, Fear and Evasion
- Now Playing
Ebola Outbreak 5:39
Ebola's Patient Zero
36 Hours
Now PlayingTravel 5:31
36 Hours in Casablanca
- Now Playing
Magazine 5:12
Fire and Ice: Mt. Kenya's Lost Glaciers
Now PlayingOpinion 4:55
Toys of War
- Now Playing
Ebola Outbreak 3:52
Limiting Ebola's Spread in Mali
Now PlayingOpinion 8:25
Gorillas in the Crossfire
- Now Playing
Ebola Outbreak 6:51
Inside the Ebola Ward
- Now Playing
Ebola Outbreak 7:30
Fighting Ebola Outbreak Street by Street
- Now Playing
Errol Morris: Peace Films 17:09
Leymah Gbowee: The Dream
- Now Playing
Ebola Outbreak 1:39
Modern Technologies and the Ebola Fight
- Now Playing
International 3:52
Boko Haram Kidnapping Tactics, Explained


text:
Have you ever watched a movie and wondered what single frame could perfectly summarize the entire film? Well, Geoff Todd did and his resulting creation is One Perfect Shot, a Twitter account that does just that. Read more…
Posts Tagged 'frames'
Incredible Focus Stacked Time-Lapse Video of Coral Made Up of 150K RAW Frames
If you're ready to have your mind blown for the next three and a half minutes, go ahead and press play. And keep in mind that the masterpiece your eyes are about to take in was anything but an easy task.
Created by videographer Daniel Stoupin from 150,000 22-megapixel RAW exposures, he put together a 4K masterpiece (despite Vimeo only showing it as 1080p). Read more…
212 Instagrammers Join Forces to Create Stop-Motion Car Video
Never underestimate the power of 212 Instagrammers. Now that might seem like a strange thing to say, but vehicle manufacturer Lexus quite literally put over 200 mobile-phone-toting-picture-takers on a lot with a 1,400-foot track and let them go to town on the 2014 Lexus IS F SPORT — a vehicle we all would probably like to see sitting outside our front doors. Read more…
Giant Picture Frame Shaped Like a View-Master Paper Disk
If you grew up enjoying 3D stereoscopic photos using a View-Master, then this picture frame is sure to cause a pang of nostalgia. It's a giant photo frame for your wall that's shaped like the paper slide holders used by the popular children's toy. It's sold by online shop Unkl347, but you might be hard pressed to find it in stock.
Wall Frame (via The Fancy)
Photo Frame in the Shape of Sunglasses
Check out this unique picture frame by Urban Outfitters. The Sunglasses Photo Frame is a "kooky oversized sunglasses picture frame" that shows your 3.5×2.75 photos through the two lenses. The temple arms work as a stand for the frame.
Read more…
Handmade Wooden Frames for Polaroid Pictures
Polaroid pictures might have an iconic look, but finding an elegant frame for them requires more than a trip to your nearest department store. Swiss design group Refurnished has a beautiful "Polaroid SX70 frame" that protects your white-bordered pictures inside a handmade wooden case.
Read more…
Digitally Altered Images That Turn Ornate Picture Frames Into Art
On a trip to the famous Louvre in Paris, photographer and artist Taylor Holland found himself more drawn in by the highly ornate frames around the art than with the art itself. This got him thinking about a project that would challenge "the viewer's notion not only of what art is, but the viewer's own perceptions about where to find and appreciate art in various settings such as the Louvre." Thus was born Fra[mes]. Read more…
Creating Still Photographs by Extracting Frames from HD Video
Are we close to the point at which HD video cameras are so good that professional photographs can simply be extracted from footage rather than shot with a still photography camera? That's a question photographer Kevin Arnold had, and when he finally got his hands on a $65,000 RED camera he decided to seek an answer:
What I hadn't anticipated going into this was the advantages this style of shooting would offer in terms of capturing natural expressions and key moments. Obviously, when you're shooting 120 frames-per-second, it's almost impossible to miss a moment. But there's more to it. Shooting video is comparably silent and, without the constant clicking of the shutter reminding them that their every movement was being recorded, the athletes were able to forget I was there. This is huge when you're striving for authentic, candid images, a hallmark of my work.
On the flip side, Arnold found that one of the biggest issues was achieving fast enough shutter speeds for sharp frames, as most of the frames in his videos were plagued with some kind of blur. Head on over to his blog to read his in depth exploration.
Stills, Meet Motion (via A Photo Editor)
Image credit: Photographs by Kevin Arnold
Upgrade the Look of Black Picture Frames with Spray Paint and Painters Tape
After seeing some elegant black picture frames with brass edges in a designer magazine, Courtney of A Thoughtful Place realized that she could create the same look on the cheap by using some plain painter's tape and a can of brass spray paint. The project takes a couple hours to complete and a few dollars in supplies, and is a thrifty way to add a dash of style to your home if you don't want to shell out money for pricey frames.
DIY Brass Frames: HB Knock Off (via Lifehacker)
Image credits: Photographs by Courtney/A Thoughtful Place
Use Wax Paper to Plan Out Your Picture Frame Layout on the Ground
If you're planning to hang a bunch of picture frames on a wall, Marissa Waddell of Roost suggests laying them out on the ground to figure out frame placement. Once you're happy with how the frames look, simply take a large sheet of wax paper and outline the frames. The paper can then be used as a guide for where to hammer in nails on the wall, giving you the exact layout you came up with.


text:
Created in this Craftsy Course
Take your serger out of the closet! Learn the fundamental setup stitches, then make three posh projects: an exposed zipper bag, an ombré ruffled apron and a striped knit scarf.
Other projects made as part of this class:
See All Class Projects »Offer some kudos...
Join the conversation...
Ask a question...
Add your comment...
Here are some details about my project: | |
Category | Sewing |
Type | Accessory |
Sizing | Women |
Style | Whimsical |
What are you most proud of? I used what I had on hand, which wasn't fusible fleece, but craftfuse. I also didn't have a nylon zipper. I think that the zipper was polyester, so I was cautious serging around it. I did need to reinforce the seam with my sewing machine...because I think that I was too cautious :-) I really like it, it is the first time I was able to use my serger on a project without feeling like I didn't understand what to do. Thank you Amy!!!!
Beautiful! I really love the double pull zipper. How handy! Did you buy a longer zipper to keep the pulls out of the way, or have any issue serging around them?
The zipper was the only one over 7" that I had :-) I was super nervous about serging over them. So much so that I put the end of the zipper on one side so I one had to go thru teeth on one side. I think that I am gonna make another with a shorter zipper and use fabric to extend the length to the end.


text:
Mind Control Forum, submitted by Sally. Mind control is one of those great conspiracy theories that has probably been with us longer than recorded history. I'm sure back before human knew how to write they were grunting about Memnoch the tribal shaman using herbs to control the minds of the rest of the tribe. Back then the conspiracy theorists probably would have burned poor Memnoch alive, these days they just get together and share made up stories about government and alien mind control plots.
HI, I would like to introduce myself. I am Heart I am the web site manager. Mind Control Forum has undergone some changes since its' beginnings. You can read about that in Ed Light's statement below and the Message from MTCs' founder Carrie Dawn.I first came across this site a few years ago and could not believe the wealth of information here. I have read all of the CKLN-FM radio series, it has been very useful to me learning and knowing about mind control with Ritual abuse survivors. Reading other articles that are posted here also gives allot of inside information that can help survivors to heal from the trauma that has been inflicted.
Heart has a web site of her own where we can find out a little bit more about the woman behind the legend.
As some of you know my site is about Multiple Personality Disorder or DID as they call it now. I don't think we are did's but do's because we can do it and no one can tell us any different. I really perfer MPG, Mulitiple Personality Gift. Because it is a gift that was given to us by what ever way it was given.
Oh, that's fantastic, she has "Multiple Gift Disorder" or whatever she called it! That adds HEAPS to her crazy conspiracy theory credibility. The only way it could be better is if she had another site full of baby pictures of her stillborn baby.
Be sure to sign Heart's Guestbook while you're looking around her informative sites!
The Upper Kitchen Cabinet Where Your Roommate Keeps His Food: You'll 'need the footstool' to reach your roommate's 'fine selection' of 'stale cereal,' but he'll never notice if 'only a little is missing from each box.' Feel less guilty by reminding yourself that Jeff 'acts weird around your girlfriend,' and always 'asks about her.' What a 'creep.'
This is the crown jewel of my erotic lamp collection, and a must-have for any serious pleasure lamp collector.
This ain't your daddy's globe...! .... or is it?!
*Galaxies and stars explode, revealing the Sports Center logo as the center of the new universe.*
'Sitcoms are so bad that they couldn't GET any worse haha.' 'Whoa buddy you're wrong... dead wrong!'
Awful Links of the Day spotlights the worst and weirdest websites on the internet. And we're not talking "weird" in a good way either.
Copyright ©2015 Rich "Lowtax" Kyanka & Something Awful LLC.