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Masala King Prawn Recipe Cooking Show
Masala King Prawn Recipe is a fine sea food to try this out which is really a healthy as well as tasty to have it.
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How to make Channa Masala - a delicious recipe that you'll love
Here is a great recipe for Channa Masala. This is one of the most popular dishes in the world. It's vegetarian, tasty and pretty simple to make. Here we show you how
Added: 1877 days ago by
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Delicious Masala Idly Recipe Cooking Show
Watch how to prepare Masala Idly which is a nice and tasty reicpe from south just try this healthy dish to have.
Added: 1878 days ago by
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Chilly mutton masala Recipe Cooking Show
This a popular South Indian spicy mutton recipe. This recipe serves four people and is good to pair with rice.
Added: 1881 days ago by
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Channa Masala Recipe Cooking Show
Here is a recipe for Channa Masala, it's an easy dish to make and vegetarian too.
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The Boulder County Parks and Open Space Department will conduct irrigation ditch, agriculture and forestry wood pile burns on county open space lands this spring.
Agricultural and irrigation ditch burns will occur between now and the end of the year as conditions allow.
Dear Editor,
Like most everyone else in Lyons, and many of the other communities in the Front Range, the floods of September 2013 will always be a "before and after" event in my life. In the weeks and months following the
Login to read more: I Still Have Faith in this Community
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Town Of Lyons Board Of Trustees Meeting
7 p.m., Monday, February 2, 2015
Shirley F. Johnson Council Chamber, Lyons Town Hall, 432 5th Avenue, Lyons, Colorado
Dearest fellow Lyons-ites,
I value open space as much as the next person, BUT, how can one think for more than ten seconds about the
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The normal Monday night meeting for the Board of Trustees (BOT) was held on Tuesday this week to accommodate the legal holiday celebrating Dr. Martin Luther King's birthday. A full agenda got considerably thinner when two applications for business licenses for medical and
At approximately 4:45 p.m. on Wednesday, January 21, Boulder County Communications received a 9-1-1 call from the Bank of Estes Park, located in the Niwot Market, 7980 Niwot Road. The caller reported two males had entered the bank, demanded money and left on foot.
Boulder County Area Agency on Aging, a Division of Community Services, offers two training programs beginning in February for family caregivers of older adults; one focused on the hands-on skills of caregiving, and the other on caregiver self-care.

subset: commoncrawl


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The Emmy Award-winning Making It Grow! is a live, interactive call-in program produced by ETV and Clemson University. Host Amanda McNulty from Clemson Extension along with Clemson Extension Resource Agent Terasa Young and featured guests including Dr. John Nelson from the USC Herbarium focus on gardening topics, while highlighting interesting places and products from around the state. Watch on Tuesdays at 7:00 pm on ETV and at 8:00 pm on the SC Channel. Also, watch on Saturdays at 3:30 pm on the SC Channel.
Full Episodes | 157
See AllMaking it Grow January 20, 2015
Making it Grow January 13, 2015.
Making it Grow.
The feature segment is an interview with Cory Tanner.
Making it Grow was recorded live on November 11, 2014.
Making it Grow was recorded live on November 4, 2014.
Making it grow was recorded live at our ETV Sumter studios on October 21, 2014.
The feature segment is a creative home landscape in Spartanburg.
Watch videos from your favorite PBS KIDS shows with the PBS KIDS Video app for your tablet or phone.
Downton Abbey Collection
Bring home the complete collection: DVDs, Blu-rays, books, gifts and more. Visit ShopPBS.


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Dicom CD Burner
Dicom Images to CD, DVD, Blu-Ray Discs
DicomBurn application is an automated Dicom CD Burner solution with a built-in Dicom server/Dicom network communicator, creates Dicom CD, DVD, Blu-Ray Discs. CD/DVD burning happens automatically as Dicom Images are sent from PACS Systems, Imaging Modalities, Worklist (MWL) Servers, NAI Dicom Box, or any on-site/remote Dicom Imaging Network. DicomBurn can be installed in PACS workstations and standard office PCs.
Dicom CD Publisher
Dicom CD Printing, Labelling & Disc Burning
Radiology/Medical CD Publishing with DicomBurn and Primera Disc Publishers
Dicom Disc Publisher is a operator-less/standalone Dicom CD burning and label printing solution. DicomBurn software integrates with Primera CD Publishers for printing customized labels on CD, DVD, Blu-ray discs. Dicom Disc Publisher automatically gathers disc label data from Dicom images and create patient label CDs. Options include adding Dicom Viewers, kiosk/silent mode burner, single or multiple studies per disc.
Dicom USB Burner
Distribute Dicom Studies to Portable Memory Drives
Dicom USB Burner application burns Dicom studies to USB drives such as memory sticks, , dongles, external HDDs. The process is simple as select all imaging studies and dicom-send to a USB HDD drive as an easy backup for offices with no backup and low tech skills. Similarly a USB pen drive could be used for quick random backups, or hand out study images to radiologists, referrals or in an outpatient facility. Imprinted Dicom USB sticks having Imaging facility name, logo, Image acquisition details can be distributed to patients.
Request Quote
Please fill in the form.
We will respond to your message as soon as possible, usually within 4 - 6 hours.


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Spamming on the financials BEGGING for investors. Lots of meaningless statements being posted to try and be relevant. Don't touch it!
Sentiment: Strong Sell
How is this a "small cap"??? It brings in less than $5million in revenue! I think you mean "micro cap".
Gotta love when a mass spamming campaign comes out pimping the $not out of a penny stock and then the board and/or CFO comes out and says "we know nothing about this". Yeah, sure u don't! I've seen this a MILLION times folks, it's a SCAM and if you buy in now you will lose. If somehow you made money in this thing...good for you...now get out! Time will show the truth. You've been warned.


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Please enter search term
Search by category, business name or keyword e.g. restaurants
Location in Phuket (or Phang Nga & Krabi), e.g. Patong. Leave blank to search ALL Locations
Tropical Garden Resort
Kata, West PhuketDrive time from Phuket International Airport is approximately 43 minutes and 20 minutes to lively Patong beach.
Is this your business?
Claim ownership and edit this business listing - it only takes a few moments! Just click on the "Claim Business" button and complete the simple form.
247 Koktanode Road, Kata Beach, A. Muang, Phuket 83100 | |
www.tropicalphuketresort.com/ | |
[email protected] | |
+66 (0)76 285 211-9 | |
+66 (0)76 285 210 | |
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January 24 |
Featured Business
Recent Reviews
Kata Rocks Restaurant
OMG the chic, elegant architecture and design of this restaurant is a must see. The menu has a mix o
Trattoria Capri Da Rico
Fabio was charming and professional. Thoroughly enjoyed our seafood pasta and dessert of Tiramisu. R
The Speakeasy Phuket
Loved the decor, the place is filled sofas and arm chairs, including a long leather Chestfield loo
SALA Phuket Restaurant
We dined upstairs. It was stunning and romantic being under the stars, watching and hearing the sea.


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Telephone & Addresses
Adam Aaron Holden (Age: 31)
33301 Fort Lauderdale FL
Adam Ben Holden (Age: 50)
94583 San Ramon CA
Adam Blake Holden (Age: 20)
32407 Panama City Beach FL
Adam Holden, Bohemia, US, Sycamore Ave, Ste 72
View Adam L.'s social profiles and photos on Facebook, MySpace, and +40 Networks.
Yellow Page contacts
Adam Holden by Adam Holden on Prezi
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North Miami Beach, FL, Hillel Community High School
George Kenyon Holden - Australian Dictionary of Biography
George Kenyon Holden (1808-1874), solicitor and politician, was born in Worcester, England, son of Adam Holden, sugar-refiner, and his wife Maria, née Gillam ...
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IMDB Filmography: Adam Holden
Actor, Swimmer
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Bad news
legacy.com: Adam H. Holden
HOLDEN - Adam H. Holden passed away January 15, 2006. Arlington Park Funeral Home.
legacy.com: Adam H. Holden
HOLDEN Adam H. Holden, age 29 left us to be with Christ Jesus on Sunday January 15, 2006. He was born July 15, 1976 and was predeceased by his grandparents Frank Holden and Carrie
findagrave: Holden, Adam H
07/15/1976 - 01/15/2006, Jacksonville (Duval County, Florida)
Anthony Holden Obituary - Palm Northwest Mortuary and Cemetery | Las...
Obituary for Anthony Holden, Anthony Holden, 29, a member of Local 12, passed away Friday, Aug., 17, 2012. He was born Jan. 23, 1983, in Escondido, Calif....
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Adam Holden is fundraising for The Benevolent - JustGiving
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Adam Holden's Fundraising Page
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Books & Literature
Re-building Manchester: the Discursive Construction of the Urban ...
Adam L. HOLDEN, University of Manchester. School of Geography. Publisher ...
Adam and Holden (Men of Smithfield #4) by L.B. Gregg — Reviews,...
Adam and Holden has 758 ratings and 105 reviews. Jenre said: In and Out is the fourth and final book in the Men of Smithfield series by LB Gregg. I've e...
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A Genealogical and Heraldic History of the Landed Gentry of Great...
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Adam Holden-bache, Ceo/managing director at Mass transmit
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Adamholden, Professor at Fort hays state university | SlideShare
View all of adamholden's Presentations.
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adam holden - YouTube
Tame Impala Performs Feels Like We Only Go Backwards Live at Radio 104.5 Philadelphia 19th June 2013. adam holden commented on a video 1 year ago.
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Butch Jones, the new football coach for the University of Tennessee, shakes the hand of 22-year-old Adam Holden after speaking during a ...
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ANINE MARIE LUFHOLM | Duluth News Tribune
and Adam L. Holden of Lake Nebegamon and her mother, Lois Lufholm of Duluth
Reports & Statements
Adam Holden
Longtime educator Dr. Adam Holden presently serves as an Adjunct Professor for Saint Bonaventure University and an Assistant Professor in Fort Hays State ...
Member Adam L Holden @ All About Jazz
www.allaboutjazz.com/php/profile.php?id=45318Member account: Adam L Holden @ All About Jazz.
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The Kooples Campaign FW 2013-14 - Adam Holden, Bambi Northwood Blyth by Raphael Elicha - 9/4/2013.
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GRETNA – Two law enforcement officers and their employers are being sued for allegedly injuring a man in a car accident. John Polk Jr. filed ...
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This week has been non stop go, go, go… A quick recap: Monday We visited with a neurodevelopmental pediatric specialist. I was overwhelmed, driving two hours with two kids for a two plus hour appointment to then drive two hours home. I normally take my dad with me to clinics to help out with the kids so I can actually communicate with the doctors, but he was home packing for his trip to visit his family in Spain. Most of the visit went well. I only had to carry both kids through the parking deck by their arms because they both decided at the same time that their feet were not working. The conclusion of this visit is that Nathan is an inflexible, rigid personality. No drugs required thank God, he needs no more medicine than he is already on. Basically for a normal child, the parent would decrease the amount of pediasure/milk to increase hunger to the point where the child would eat. This does not hold true for Nathan. He is so strong willed that he would rather starve and dehydrate himself – remember how his blood sugar was crashing at 24 when he was admitted to the PICU a few weeks ago. We left this visit with a referral to a applied behavioral analyst at a feeding and swallowing clinic. As soon as we returned home, we had to hop right back in the car to drive my dad and brother to the bus stop. Being that the bus stop was 5 minutes from my husband's job and my anxiety level was peaking, we made a quick visit at the end of his work day to meet his coworkers. Perk of the visit: sending kids home in daddy's car, making a pit stop to walk around DSW aimlessly, trying on shoes, and not spending a penny. Tuesday A pretty low key day at home. Had business to take care of and needed to be home for two clients to stop by. Wednesday Another visit to the hospital, this time to see Nathan's CF team and pulmonogist. My father in law watched Teagan which helped tremendously. The traffic stunk but what was even worse – forgetting my wallet at home, no money for breakfast, no money for parking, no money for lunch, no money period. We arrived 15 minutes late because of the horrible traffic, I kept popping off the highway to take parallel running back roads. Nathan and I had some deep conversations about whether or not I had Nathan when I was a baby. One main conclusion to our discussion is that Nathan wants "this many *raise both hands, ten fingers* baby brothers". He says he will ask God to give him baby brothers and the proceeded to name them all funky names beginning with "sinbastar". Sorry Nathan, but looks like you will have to be happy with one little sister named Teagan. Clinic update: Nathan is 36 pounds, not terrible but slowly falling off his curve. We definitely need to follow up with feeding and swallowing clinic ASAP. His doctor brought up the possibility of utilizing a feeding tube (gtube) again. Since we know limiting the pediasure isn't going to lead him to eat solid food, we are temporarily lifting the limit on his pediasure consumption. For the time being he should be having 4-5 cans of the 1.5 cal pediasure. If his stool sample still cultures c. dif (I already collected, it's in the test tube, triple bagged thanks to mother in law, in my freezer) then after he finishes flagyl next week he will go on vankomycin. By the time we finished up at clinic I was starting to get dizzy. It was mid afternoon and I was still running on an empty stomach, not even a spark or a pumpkin spice latte to carry me over. I googled that domino's pizza accepted paypal but my phone was nearly dead, my dad's kindle wouldn't connect to the wireless, and I had no money to exit parking deck. Luckily, at the gate I called an attendant to explain the problem to and he gave me a deferred payment slip. And then my husband came to the rescue and ordered me a Hawaiian pizza and a diet coke at a nearby domino's and managed to give me directions just before my phone died. Today A day of mixed emotions, spent crafting and woodworking. Don't feel like revisiting much of what I felt today. Tomorrow …will be a new day and a clean slate. Praying for my soul friend who is having surgery early tomorrow morning. That's all folks. |
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You can get to Dutch Hill Cemetery by heading towards Washingtonville and then taking Rt. 642 east through Jerseytown. The cemetery is on the left side of the road not far from Millville. Notify Administrator about this message?
Home | Help | About Us | Site Index | Jobs | PRIVACY | Affiliate |
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Dr. Gregory J. Radio, MD
Obstetrics & Gynecology, Obstetrics & Gynecology Associates Of Lehigh Valley
- 5649 Wynnewood Dr Ste 102
Laurys Station, PA 18059 - 2 Office Locations
- (610) 262-5899
Dr. Gregory J. Radio graduated from the Pennsylvania State University College of Medicine in 1973. He works in Laurys Station, PA and 1 other location and specializes in Obstetrics & Gynecology. Dr. Radio is affiliated with Lehigh Valley Hospital Cedar Crest and Lehigh Valley Hospital 17Th Street. He speaks English and Spanish.
Gender: Male
Years in Practice: 42 Years
Languages Spoken: English, Spanish
Medical School: Pennsylvania State University College of Medicine
Graduation Date: 1973
Hospital Affiliations: Lehigh Valley Hospital Cedar Crest, Lehigh Valley Hospital 17Th Street
Specialties: Obstetrics & Gynecology
*This physician has multiple office locations. See Appointments for details.


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Baltimore, Take Steps to Find a Cure!
Take Steps for Crohn's & Colitis is CCFA's largest fundraising event having touched over 240,000 people and raised nearly $60M to help further the Foundation's mission.
Our Take Steps walks offer a wonderful day for family, friends and the community to celebrate all of the efforts that have been put forth in raising funds towards our mission. Our walk events are filled with live music, food, kids' entertainment, educational materials, and, of course, wonderful exposure for our corporate partners. In 2014, more than 70,000 people joined us nationwide, helping us raise $11M.
82 cents of every dollar raised goes towards breakthrough research, public and professional education, and patient support services in communities across the nation.
Register today. Join thousands of others in the fight against digestive diseases.
The Take Steps for Crohn's & Colitis walk is the nation's largest event dedicated to finding cures for digestive diseases. Many patients have only ever met a handful of other patients suffering from IBD – this is a unique opportunity to meet hundreds of IBD patients, families, and supporters from your own backyard. There is no fee to register and no team is too big or small!
Walk day is an incredible experience for all to celebrate the efforts that have been put forth in raising funds toward our mission. It is a day filled with live music, food, kids' activities, educational materials, and of course wonderful exposure for our corporate partners.
Here are a few proven tips to help you have a rewarding and successful walk experience with your team!
Step 1: Set a realistic and meaningful goal for your team
There is no cost to register and no fundraising minimum. It is up to you to set a personally meaningful and significant goal for you and your team. Communicate that goal to your team members and work together to achieve it dividing the goal among each other.
Step 2: Write Personal Fundraising Letters & Emails
Compose a passionate and individualized letter about why you are walking and how people can support your fundraising efforts.
Step 3: Recruit Participants
Ask your friends, neighbors, family members and co-workers to join your team and help you to spread awareness and reach your team's fundraising goal through their contacts.
Step 4: Raise Money
The national fundraising average per person is $250 encourage your each of your of your team members to beat the national average. Approach the businesses you frequent, or even better, ask your own company! Lead by example, by making the first donation your own!
Step 5: Create Excitement
Design a team t-shirt or a unique team name, post flyers in your neighborhood, and share information on social media!
Step 6: Celebrate Your Team's Success
Attend the Walk. Take a team photo. Eat, drink and celebrate raising funds to find cures for Crohn's and colitis!
Have you collected donations that need to be applied to your fundraising page?
Maryland/Southern Delaware Chapter
ATTN: Misty Keens
1201 S. Sharp St.
Suite 107
Baltimore, MD 21230
Visit the Maryland/Southern Delaware Chapter website here
Find a support group here


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We Have One Big Issue With Justin Bieber's Apology
We accept your apology, but…
The Top 10 Covers of Mark Ronson & Bruno Mars' 'Uptown Funk' (So Far)
Don't believe us, just watch!
118 Thoughts Everyone Has Watching Broad City For The First Time
"I hate Bevers."
Quiz! How Well Do You Know The Lyrics To Blink 182's Biggest Songs?
Test your skills!
June 14th, 2004
The MMVA mayhem has begun!?I've been?climbing over piles of half-finished sets and lighting gear and inhaling sawdust particles all day…and LOVING EVERY MINUTE OF IT! There's this energy that fills Much HQ the week before the big bash that is unlike any other time of the year!
This morning Devon and?I went on a covert mission into the parking lot, where they were setting up the main stage, to take the photo of the day. Luckily he was wearing a hardhat/sunglasses disguise so people would just think he was part of the construction crew…
Now I have to figure out what area to infiltrate tomorrow…
Posted on Monday, June 14th, 2004 at 5:19 pm by Kelly and is filed under Blog.


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US 2883861 A Abstract available in Claims available in Description (OCR text may contain errors) United States Patent LIQUID LEVEL INDICATOR Howard E. Van Valkenburg, Candlewood Isle, and Raymond E. Sansom, Bethe], Conn., assignors to Sperry IYI'OILIIMS, Inc., Danbury, Conn., a corporation of New Application June 14, 1957, Serial No. 665,860 4 Claims. (Cl. 73-290) This invention relates to means for measuring the liquid level within a container by ultrasonic means. 7 A large number of liquid level measurement problems cannot be solved with presently known techniques. Such problems arise, for example, in a variety of atomic reactor applications involving sealed tanks having high temperatures, turbulence, bubbling, pressure, or corrosive conditions. It is an object of this invention to provide an ultrasonic liquid level measuring device capable of absolute calibration because it does not depend on the velocity of the ultrasonic vibrations in the liquid. It is a further object of the invention to provide an ultrasonic liquid level indicator which may employ high frequencies and thus permit the use of small piezoelectric transducers. It is a further object of this invention to provide an ultrasonic liquid measuring device which does not depend upon the reflection of pulses from a discontinuity, and thus there is eliminated problems due to reverberation in tank walls, reflections from bubbles and similar conditions. Further objects and advantages of this invention will become apparent in the following detailed description thereof. The accompanying drawing is an assembly view partly sectioned vertically and partly diagrammatic showing one embodiment of this invention. Referring to the drawing, there is disclosed a tank 10 within which there is a body of liquid 11, whose depth is to be determined. For this purpose there is provided a series of rods 12a, 12b, 12c, and so forth, extending through the top 15 of tank 10, and fastened thereon as, for instance, by welding. The portions of the rods extending into the tank are of progressively increasing length from a point adjacent the top of the tank to a point adjacent the bottom of the tank. Cooperating with the rods 12a-12f is a series of rods 14a-14f extending through the bottom wall 16 of tank 10 and fastened therein in any suitable manner, as, for instance, by welding. The rods of each pair are in alignment and are spaced from each other lengthwise to provide a small gap 20 to form a discontinuity. A piezoelectric element 30a, 30b-30f is applied to the outer end of each of the upper rods and a similar piezoelectric element 31a, 31b-31f is applied to the outer end of each of the lower rods. It will now be seen that if the piezoelectric elements 30a-30f are energized to generate ultrasonic pulses, such pulses will travel down rods 12a-12f. If no liquid appears to close the gap 20, the pulses will not be transmitted to the corresponding lower rods. This is the case in the example shown in the drawing with respect to rods 12a, 12b and 12c because there is an air gap suflicient to prevent transmission of the pulses to the corresponding lower bars 14a, 14b, 14c. However, the gap 20'between upper rod 12d and lower rod 14d is closed by the liquid which is a good transmitter of sound, and hence the pulse gen-- 2,883,861 Patented Apr. 28, 1959 erated by crystal 30d will be transmitted through rod 12d, the liquid 20, rod 14d to the receiver crystal 31d. The same is true with respect to the pair of rods 12e--14e and 12f--14f. In order to utilize the foregoing arrangement to give an indication of liquid depth, there may be employed the oscilloscope 40 having horizontal plates 41 between which a sweep is generated by a sweep generator 42 energized periodically by a synchronizer 43. The synchronizer may also energize a pulse generator 44 so that these pulses are synchronized with the sweep. The pulses generated by pulser 44 are applied simultaneously to the entire set of transmitting transducers 30a-30f which are connected in parallel. The receiving transducers 31a-31f are also connected in parallel and their output is fed to a receiver amplifier 45 so that the amplified signal may be applied to the vertical plates 46 of the oscilloscope to deflect the sweep if a signal is received by any of the transducers 3111-31 The sweep of the oscilloscope represents a certain time interval, and in order that discrete indications along the sweep corresponding to the respective pairs of rods may be obtained, the sum total length of the pairs of rods (including the gap 20) is made progressively longer. The time of travel of the pulse from the transmitting transducer to the receiving transducer will thus be different for each pair of rods, and the received signals will appear at different points along the sweep length. The diflerent effective lengths of the pairs of rods may be obtained by making the portions of the rods 12a-12f projecting out side the tank of increasing length. Thus, for the six pairs of rods, pulses received by their receiving transducers 31a-31f will appear on the oscilloscope sweep at the six spaced points shown. Referring to the oscilloscope 40, it will now be seen that the pair of rods in position 1 corresponding to high depth of liquid will not transmit the pulse because of the attenuation by air gap 20, and a blank will appear at position 1 of the sweep corresponding in time to the time it would take the pulse to travel through rods 12a--14a and the gap 20. Similarly, no indication appears on the oscilloscope at position 2 or position 3 corresponding to the time it would take the pulse to travel the increasing lengths of rods 12b-14b and 12c-14c and their gaps 20, because the liquid level does not cover the gap 20 between these rods and the corresponding rods 14b and 140. At position 4, however, the pulse applied to crystal 30d is received by crystal 31d because the liquid in the tank covers the gap between rods 12d and 14d, and the liquid being a good conductor of ultrasonic vibrations, the pulse is received. This is disclosed by the oscilloscope at position 4 where the sweep is deflected. Similarly, deflections are received at positions 5 and 6, corresponding to the travel of the pulses through the rods 12:? and 12 to their cooperating rods Me and 14 Therefore, the first pulse to be indicated along the oscilloscope sweep is a measure .'of the depth of liquid in the tank, and the sweep of the oscilloscope may be calibrated directly in terms of linear depth within the tank. A continuous rod 50 without any gap or other discontinuity therein may be provided with a transmitting crystal 50a and a receiving crystal 50b so that the pulse will always be transmitted therethrough regardless of liquid level and thus give an indication of the operativeness of the system and provide a calibrating position for setting the start of the sweep. The number and positioning of the pairs of rods within a tank may be varied for finer or coarser indication. Having described our invention, what we claim and desire to secure by Letters Patent is: 1. A device for indicating the level of liquid within closed containers, comprising a plurality of pairs of sound-conducting members extending into the container, one member of each pair extending into the container through the top thereof, the cooperating member of each pair extending into the container through the bottom thereof, the ends of the members of each pair within the container being spaced apart normally to prevent passage of ultrasonic vibrations from one member of a pair to the other member in the absence of liquid spanning the space, the spaces between the respective pairs occurring at different distances above the bottom of the container, means for generating ultrasonic pulses, means for transmitting .said pulses into the members extending into the top of the container, means connected to the members extending into the bottom of the container for receiving said pulses, the total length of said pairs of conducting members and their spacing varying progressively to provide difierent traverse times for the passage of the generated pulses, and means for indicating the received pulses. 2. A liquid level indicating device as specified in claim 1 in which the means for transmitting said pulses into the members extending into the top of the container are piezoelectric transducers energized by the pulse generating means and connected to said members, and the means 4 connected to the members extending into the bottom of the container for receiving said pulses are piezoelectric transducers connected to said indicating means. 3. A liquid level indicating device as specified in claim 2 in which all transmitting transducers are connected in parallel and all receiving transducers are connected in parallel. 4. A liquid level indicating device as specified in claim 3 in which the means for indicating the received pulses includes an oscilloscope having a sweep generator, means for synchronizing the sweep generator with the pulse generating means and means for deflecting the sweep by the pulses received by the receiving transducers. References Cited in the file of this patent UNITED STATES PATENTS 2,534,006 De Lano et al. Dec. 12, 1950 2,713,263 Turner July 19, 1955 2,746,480 Hildyard May 22, 1956 2,787,158 Valkenburg et a1. Apr. 2, 1957 FOREIGN PATENTS 736,464 Great Britain Sept. 7, 1955 Patent Citations
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Publications (26)99.37 Total impact
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ABSTRACT: Maillard reaction products are known to have anti inflammatory property. Objective of this study was to assess anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal and its action mechanisms. Lipopolysaccharide (LPS)-activated macrophage (RAW264.7) and synoviocytes were treated with (E)-2,4-bis(p-hydroxyphenyl)-2-butenal for in vitro assay. (E)-2,4-bis(p-hydroxyphenyl)-2-butenal (5 mg/kg) was also periorally administered for 30 days to collagen (50 μg/g) induced arthritic mice. Clinical score, histopathological exam, NO generation, iNOS and COX2 expression, and NF-κB/IKK and STAT3 activities were determined in cultured cell and joint tissues of mice. Binding of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal to STAT3 was evaluated by a Pull-down assay and its binding site was predicted using molecular docking study with Autodock VINA. (E)-2,4-bis(p-hydroxyphenyl)-2-butenal (2.5-10 μg/ml) inhibited LPS (1 μg/ml)-induced NO generation, iNOS and COX2 expression, and NF-κB/IKK and STAT3 activities in macrophage and synoviocytes. (E)-2,4-bis(p-hydroxyphenyl)-2-butenal suppressed the collagen induced arthritic responses through inhibition of the expression of iNOS and COX2, and NF-κB/IKK and STAT3 activities, and also reduced the extent of bone destruction and fibrosis in joint tissues. A Pull-down assay proved that (E)-2,4-bis(p-hydroxyphenyl)-2-butenal interfere with the binding of ATP to STAT3. Subsequent docking study proposes that (E)-2,4-bis(p-hydroxyphenyl)-2-butenal binds to the the DNA binding interface of STAT3 possibly causing ATP binding to STAT3 in an allosteric manner. (E)-2,4-bis(p-hydroxyphenyl)-2-butenal exerted its anti-inflammatory and anti-arthritic effects through inhibition of NF-κB/STAT3 pathway via direct binding to STAT3, and that it could be a useful agent for the treatment of arthritic disease.British Journal of Pharmacology 02/2014; · 5.07 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: The medicinal properties of functionally active organosulfur compounds such as allin, diallyl disulfide, S-allylmercaptocysteine, and S-trityl-L-cysteine isolated from garlic have received great attention by the large number of investigators who have studied their pharmacological effects for the treatment of various diseases. These organosulfur compounds are able to prevent for development of cancer, cardiovascular, neurological, and liver disease as well as allergy and arthritis. There have been also many reports on toxicities and pharmacokinetics of these compounds. The aim of this study is to review a variety of experimental and clinical reports, and describe the effectiveness, toxicities and pharmacokinetics, and possible mechanisms of pharmaceutical actions of functionally active compounds isolated from garlic.Pharmacology [?] Therapeutics 12/2013; · 7.75 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: The Maillard reaction products are known to be effective in chemoprevention. Here, we focused on the anti-cancer effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal on in vitro and in vivo colon cancer. We analysed the anti-cancer activity of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal on colon cancer cells by using cell cycle and apoptosis analysis. To elucidate it's mechanism, NF-κB DNA binding activity, docking model as well as pull-down assay. Further, a xenograft model of colon cancer was studied to test the in vivo effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal. (E)-2,4-Bis(p-hydroxyphenyl)-2-butenal inhibited colon cancer cells (SW620 and HCT116) growth followed by induction of apoptosis in a concentration-dependent manner via down-regulation of NF-κB activity. In docking model as well as pull-down assay, (E)-2,4-bis(p-hydroxyphenyl)-2-butenal directly binds to three amino acid residues of IKKβ, thereby inhibited IKKβ activity in addition to induction of death receptor 6 (DR6) as well as their target apoptotic genes. Finally, (E)-2,4-bis(p-hydroxyphenyl)-2-butenal suppressed anchorage-independent cancer cell growth, and tumor growth in xenograft model accompanied with apoptosis through inhibition of IKKβ/NF-κB activity, and overexpression of DR6. These results suggest that (E)-2,4-bis(p-hydroxyphenyl)-2-butenal inhibits colon cancer cell growth through inhibition of IKKβ/NF-κB activity and induction of DR6 expression.Apoptosis 09/2013; 19(1). · 3.61 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Cytokine and activation of lymphocytes are critical for tumor growth. We investigated whether interleukin (IL)-32β overexpression changes other cytokine levels and activates cytotoxic lymphocyte, and thus modify tumor growth. Herein, IL-32β inhibited B16 melanoma growth in IL-32β-overexpressing transgenic mice (IL-32β mice), and downregulated the expressions of anti-apoptotic proteins (bcl-2, IAP, and XIAP) and cell growth regulatory proteins (Ki-67 antigen (Ki-67) and proliferating cell nuclear antigen (PCNA)), but upregulated the expressions of pro-apoptotic proteins (bax, cleaved caspase-3, and cleaved caspase-9). IL-32β also inhibited colon and prostate tumor growth in athymic nude mice inoculated with IL-32β-transfected SW620 colon or PC3 prostate cancer cells. The forced expression of IL-32β also inhibited cell growth in cultured colon and prostate cancer cells, and these inhibitory effects were abolished by IL-32 small interfering RNA (siRNA). IL-10 levels were elevated, but IL-1β, IL-6, and tumor necrosis factor-alpha (TNF-α) levels were reduced in the tumor tissues and spleens of IL-32β mice, and athymic nude mice. The number of cytotoxic T (CD8(+)) and natural killer (NK) cells in tumor tissues, spleen, and blood was significantly elevated in IL-32β mice and athymic nude mice inoculated with IL-32β-transfected cancer cells. Constituted activated NF-κB and STAT3 levels were reduced in the tumor tissues of IL-32β mice and athymic nude mice, as well as in IL-32β-transfected cultured cancer cells. These findings suggest that IL-32β inhibits tumor growth by increasing cytotoxic lymphocyte numbers, and by inactivating the NF-κB and STAT3 pathways through changing of cytokine levels in tumor tissues.Cell Death & Disease 05/2013; 4:e640. · 5.18 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: High doses of acetaminophen (APAP; N-acetyl-p-aminophenol) cause severe hepatotoxicity after metabolic activation by cytochrome P450 2E1. This study was undertaken to examine the preventive effects of thiacremonone, a compound extracted from garlic, on APAP-induced acute hepatic failure in male C57BL/6J. Mice received with 500 mg/kg APAP after a 7-day pretreatment with thiacremonone (10-50 mg/kg). Thiacremonone inhibited the APAP-induced serum ALT and AST levels in a dose-dependent manner, and markedly reduced the restricted area of necrosis and inflammation by administration of APAP. Thiacremonone also inhibited the APAP-induced depletion of intracellular GSH, induction of nitric oxide, and lipid peroxidation as well as expression of P450 2E1. After APAP injection, the numbers of Kupffer cells, natural killer cells, and cytotoxic T cells were elevated, but the elevated cell numbers in the liver were reduced in thiacremonone pretreated mice. The expression levels of I-309, M-CSF, MIG, MIP-1 α , MIP-1 β , IL-7, and IL-17 were increased by APAP treatment, which were inhibited in thiacremonone pretreated mice. These data indicate that thiacremonone could be a useful agent for the treatment of drug-induced hepatic failure and that the reduction of cytotoxic immune cells as well as proinflammatory cytokine production may be critical for the prevention of APAP-induced acute liver toxicity.Evidence-based Complementary and Alternative Medicine 01/2013; 2013:974794. · 2.18 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: The Maillard Reaction Products (MRPs) are chemical compounds which have been known to be effective in chemoprevention. Death receptors (DR) play a central role in directing apoptosis in several cancer cells. In our previous study, we demonstrated that (E)-2,4-bis(p-hydroxyphenyl)-2-butenal, a MRP product, inhibited human colon cancer cell growth by inducing apoptosis via nuclear factor-κB (NF-κB) inactivation and G2/M phase cell cycle arrest. In this study, (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate, a new (E)-2,4-bis(p-hydroxyphenyl)-2-butenal derivative, was synthesized to improve their solubility and stability in water and then evaluated against NCI-H460 and A549 human lung cancer cells. (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate reduced the viability in both cell lines in a time and dose-dependent manner. We also found that (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate increased apoptotic cell death through the upregulation of the expression of death receptor (DR)-3 and DR6 in both lung cancer cell lines. In addition to this, the transfection of DR3 siRNA diminished the growth inhibitory and apoptosis inducing effect of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate on lung cancer cells, however these effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate was not changed by DR6 siRNA. These results indicated that (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate inhibits human lung cancer cell growth via increasing apoptotic cell death by upregulation of the expression of DR3.Biomolecules and Therapeutics 11/2012; 20(6):538-43. · 0.84 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: BACKGROUND AND PURPOSE: This study was performed to investigate the effects of 4-O-methylhonokiol (MH), a constituent of Magnolia officinalis, on human prostate cancer cell growth and its mechanism of action. EXPERIMENTAL APPROACH: Anti-cancer effects of MH were examined using human prostate cancer or normal cells. The effects were validated by in vivo Xenograft animal model. KEY RESULTS: Pull-down assay and molecular docking study suggested that MH may directly bind to PPAR-γ and elevate its activity. In consistent with these results, MH increased transcriptional activity of PPAR-γ, while decreased NF-κB activity. Growth inhibition of human prostate cancer cells was achieved by MH, which was blunted by PPAR-γ antagonist (GW9662). MH caused apoptotic cell death and it was related to G(0) -G(1) phase cell cycle arrest. We found that MH increased expression of the cell cycle regulator p21, and apoptotic proteins, whereas the compound decreased phosphorylation of Rb and anti-apoptotic proteins. Small interfering RNA against p21 or transfection of p21 with mutation on cyclin D1/Cdk4 binding site blocked MH-induced cell growth inhibition, and inhibition of NF-κB activity. With animal studies, MH inhibited tumor growth, NF-κB activity and expression of anti-apoptotic proteins, whereas increased transcriptional activity and expression of PPAR-γ, and the expression of apoptotic proteins as well as p21 in tumor tissues. CONCLUSIONS AND IMPLICATION: These results indicate that MH may suppress growth of human prostate cancer cells through activation of PPAR-γ, suppression of NF-κB as well as arrest of cell cycle. Thus, MH might be a useful tool for treatment of prostate cancer.British Journal of Pharmacology 10/2012; · 5.07 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Resveratrol (Res), from the skin of red grapes, induces apoptosis in some malignant cells, but there are no reports on the apoptotic effect of Res on human malignant pleural mesothelioma. We found that Res interacts with specificity protein 1 (Sp1). The IC50 for Res was 17 µM in MSTO-211H cells. Cell viability was decreased and apoptotic cell death was increased by Res (0-60 µM). Res increased the Sub-G1 population in MSTO-211H cells and significantly suppressed Sp1 protein levels, but not Sp1 mRNA levels. Res modulated the expression of Sp1 regulatory proteins including p21, p27, cyclin D1, Mcl-1 and survivin in mesothelioma cells. After treatment with Res, apoptosis signaling cascades were activated by the activation of Bid, Bim, caspase-3 and PARP, upregulation of Bax and downregulation of Bcl-xL. Res (20 mg/kg daily for 4 weeks) effectively suppressed tumor growth in vivo in BALB/c athymic (nu+/nu+) mice injected with MSTO-211H cells, an effect that was mediated by inhibition of Sp1 expression and induction of apoptotic cell death. Our results strongly suggest that Sp1 is a novel molecular target of Res in human malignant pleural mesothelioma.International Journal of Molecular Medicine 04/2012; 30(1):21-7. · 1.88 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Garlic extracts exert anti-cancer and anti-inflammatory effects. However, the anti-adipogenic effect of garlic-derived compounds remains unclear. In this study, we examined the effect of thiacremonone, a sulfur compound isolated from garlic, on adipocyte differentiation using 3T3-L1 cells. We found that thiacremonone significantly inhibited 3T3-L1 differentiation via down-regulation of adipogenesis-related transcription factors and adipogenic markers. The inhibitory effect mainly occurred at the early phase of differentiation in 3T3-L1 cells. There was no cytotoxic effect of thiacremonone in 3T3-L1 cells and treatment of differentiating 3T3-L1 cells with thiacremonone resulted in AMPK activation, which led to an attenuated expression of acetyl CoA carboxylase-1 (ACC-1), an essential enzyme for the synthesis and usage of fatty acids. Moreover, thiacremonone enhanced the mRNA level of carnitine palmitoyltransferase (CPT-1). The modulating effect of thiacremonone on expressions of genes involved in lipolysis was partially abrogated by treatment with compound C, an AMPK inhibitor. Taken together, these results indicated that thiacremonone-induced AMPK activation, inhibition of ACC-1 expression and concomitant recovery of CPT-1 expression resulted in the suppression of intracellular lipid droplet levels, suggesting that thiacremonone may induce reduction of lipid synthesis and increases in fatty acid oxidation partially mediated via AMPK activation. Thiacremonone may be a promising compound for the treatment of obesity.The Journal of nutritional biochemistry 03/2012; · 4.29 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: We isolated a substance from fructose–tyrosine Maillard reaction products (MRPs) and investigated its antiproliferative effect on six human cancer cell lines. The ethyl acetate fraction of fructose–tyrosine MRPs showed a strong antiproliferative effect; this fraction was isolated and purified using silica gel column chromatography, semipreparative RP-HPLC, and recycling HPLC. The structure of the purified compound was determined using spectroscopic methods. The isolated compound was identified as 2,4-bis(p-hydroxyphenyl)-2-butenal (C16H14O3, HPB242). HPB242 inhibited cell growth in a dose-dependent manner (10–80 μg/ml) on the six human cancer cell lines. The IC50 values of HPB242 on the six human cancer cell lines were 17.34 μg/ml (MCF-7), 29.21 μg/ml (HCT-116), 34.57 μg/ml (H-460), 34.87 μg/ml (HepG2), 48.77 μg/ml (PC-3), and 55.83 μg/ml (MKN-45).Food Chemistry 02/2012; 130(3):547–551. · 3.26 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Garlic is widely used as a spice. Garlic extracts exert anticancer and antiinflammatory effects, but its antiobesity efficacy studies have produced conflicting results. The antiobesity effects of thiacremonone, a sulfur compound isolated from garlic, was evaluated in obese db/db mice. Thiacremonone was orally administrated to mice for 3 weeks. The thiacremonone-treated db/db mice showed a loss of body weight and decrease in blood triglyceride and glucose levels compared with the control mice. Histological analysis further revealed that thiacremonone significantly decreased lipid accumulation in the fatty livers of treated db/db mice. It was observed that GLUT-4 expression and glucose uptake were up-regulated by thiacremonone in 3T3-L1 adipocytes. Thiacremonone treatment also suppressed expression levels of acetyl-CoA carboxylase (ACC) and fatty acid synthase (FAS), which are involved in lipid metabolism, in the liver of db/db mice. In addition, thiacremonone enhanced peroxisome proliferator-activated receptor γ (PPARγ) expression in the fatty liver. Taken together, these results suggest that thiacremonone may play a vital role in improving the management of obesity and related metabolic syndromes via inhibition of lipid accumulation. Copyright © 2012 John Wiley & Sons, Ltd.Phytotherapy Research 01/2012; 26(9):1265-71. · 2.40 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: PPARγ ligands have been reported to reduce proliferation of human prostate cancer cells. However, the molecular mechanism of PPARγ agonist-induced cell growth inhibition of prostate cancer cells is not clear. GSK-3β expression and NFκB activity have important roles in prostate cancer development. To investigate the mechanisms of the PPARγ agonist-induced prostate cancer cell growth inhibition, we examined the effect of troglitazone on the expression of PPARγ, GSK-3β and activity of NFκB as well as on the prostate cancer cell growth. Troglitazone induced the expression of PPARγ in the nuclear of PC-3 cells, but not in LNCaP cells. Troglitazone (0-16 uM) inhibited cancer cell growth in a similar extend between both cells accompanied by the induction of cell cycle arrest in G(0)/G(1) phase and an increased in the similar extent of apoptotic cell death in concentration dependent manner. Troglitazone inhibited the constitutive expression of GSK-3β and activation of NFκB. Co-treatment of troglitazone with a GSK-3β inhibitor (AR-a014418) or GSK-3β siRNA significantly augmented the inhibitory effect of troglitazone on the NFκB activity and on prostate cancer cell growth inhibition and apoptotic cell death. However, overexpression of GSK-3β hindered troglitazone-induced cell growth inhibition and NFκB inactivation. These results suggest that PPARγ agonist, troglitazone, inhibits prostate cancer cell growth through inactivation of NFκB via suppression of GSK-3β expression.Cancer biology & therapy 08/2011; 12(4):288-96. · 3.29 Impact Factor -
Article: 4-O-methylhonokiol inhibits colon tumor growth via p21-mediated suppression of NF-κB activity.
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ABSTRACT: Biphenolic components in the Magnolia family have shown several pharmacological activities such as antitumor effects. This study investigated the effects of 4-O-methylhonokiol (MH), a constituent of Magnolia officinalis, on human colon cancer cell growth and its action mechanism. 4-O-methylhonokiol (0-30 μM) decreased constitutive activated nuclear factor (NF)-κB DNA binding activity and inhibited growth of human colon (SW620 and HCT116) cancer cells. It also caused G₀-G₁ phase cell cycle arrest followed by an induction of apoptotic cell death. However, knockdown with small interfering RNA (siRNA) of p21 or transfection with cyclin D1/Cdk4 binding site-mutated p21 abrogated MH-induced cell growth inhibition, inhibition of NF-κB activity as well as expression of cyclin D1 and Cdk4. Conversely, inhibition of NF-κB with specific inhibitor or siRNA augmented MH-induced apoptotic cell death. 4-O-methylhonokiol inhibited tumor growth, NF-κB activity and expression of antiapoptotic proteins; however, it increased the expression of apoptotic proteins as well as p21 in xenograft nude mice bearing SW620 cancer cells. The present study reveals that MH causes p21-mediated human colon cancer cell growth inhibition through suppression of NF-κB and indicates that this compound by itself or in combination with other anticancer agents could be useful for the treatment of cancer.The Journal of nutritional biochemistry 08/2011; 23(7):706-15. · 4.29 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Oxidative stress induced neuronal cell death by accumulation of β-amyloid (Aβ) is a critical pathological mechanism of Alzheimer's disease (AD). Intracerebroventrical infusion of Aβ1-42 (300 pmol/day per mouse) for 14 days induced neuronal cell death and memory impairment, but pre-treatment of 4-O-methylhonokiol (4-O-MH), a novel compound extracted from Magnolia officinalis for 3 weeks (0.2, 0.5 and 1.0 mg/kg) prior to the infusion of Aβ1-42 and during the infusion dose dependently improved Aβ1-42-induced memory impairment and prevented neuronal cell death. Additionally, 4-O-MH reduced Aβ1-42 infusion-induced oxidative damages of protein and lipid but reduced glutathione levels in the cortex and hippocampus. Aβ1-42 infusion-induced activation of astrocytes and p38 mitogenic activated protein (MAP) kinase was also prevented by 4-O-MH in mice brains. In further study using culture cortical neurons, p38 MAP kinase inhibitor abolished the inhibitory effect of 4-O-MH (10 μM) on the Aβ1-42 (5 μM)-induced reactive oxidative species generation and neuronal cell death. These results suggest that 4-O-MH might prevent the development and progression of AD through the reduction of oxidative stress and neuronal cell death via inactivation of p38 MAP kinase pathway.The Journal of nutritional biochemistry 05/2011; 22(5):476-486. · 4.29 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Several studies have shown physiological functions of interleukin (IL)-32, a novel cytokine. However, the role of IL-32 in cancer development has not been reported. In this study, we showed that IL-32γ inhibited tumor growth in IL-32γ-overexpressing transgenic mice inoculated with melanoma as well as colon tumor growth in xenograft nude mice inoculated with IL-32γ-transfected colon cancer cells (SW620). The inhibitory effect of IL-32γ on tumor growth was associated with the inhibition of constitutive activated nuclear transcription factor-κB (NF-κB) and of signal transducer and activator of transcription 3 (STAT3). The expression of antiapoptotic, cell proliferation and tumor-promoting genes (bcl-2, X-chromosome inhibitor of apoptosis protein (IAP), cellular IAP and cellular FADD-like IL-1β-converting enzyme-inhibitory protein, cyclin D), cyclin-dependent kinase 4, cycolooxygenase-2 and inducible nitric oxide synthase was decreased, whereas the expression of apoptotic target genes (caspase-3 and -9, bax) increased. In tumor, spleen and blood, the number of cytotoxic CD8(+) T cells and CD57(+) natural killer cells and the levels of IL-10 increased, but that of tumor necrosis factor-α (TNF-α), IL-1β and IL-6 decreased. We also found that forced overexpression of IL-32γ inhibited colon cancer cell (SW620 and HCT116) growth accompanied with the inhibition of activated NF-κB and STAT3 in vitro. In addition, when IL-32γ was knocked down by small interfering RNA (siRNA) or neutralized with an anti-IL-32γ antibody, IL-32γ-induced colon cancer cell growth inhibition, the IL-32γ-induced decrease of TNF-α, IL-1 and IL-6 production, and the increase of IL-10 production were abolished. However, siRNA of NF-κB and STAT3 augmented IL-32γ-induced colon cancer cell growth inhibition. These findings indicate significant pathophysiological roles of IL-32γ in cancer development.Oncogene 03/2011; 30(30):3345-59. · 8.56 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: The bioactive constituents isolated from the bark of Magnolia officinalis such as magnolol, honokiol and obovatol have anti-inflammatory properties through the inactivation of NF-κB which is an important factor in the regulation of inflammatory reaction. We recently isolated a novel neolignan compound, 4-O-methylhonokiol, from M. officinalis. In the present study, we investigated whether or not 4-O-methylhonokiol inhibits inflammatory reaction through the inhibition of NF-κB activity. The results showed that 4-O-methylhonokiol (2.5–10 μM) inhibited LPS (1 μg/ml)-induced NO generation in macrophage Raw 264.7 cells in a concentration-dependent manner with IC50 value 9.8 μM. The inhibition of NO generation by 4-O-methylhonokiol was consistent with the inhibitory effect on the expression as well as transcriptional activity of inducible nitric oxide synthase (iNOS). In addition, 4-O-methylhonokiol inhibited the LPS-induced transcriptional and DNA binding activities of NF-κB as well as p50 and p65 translocation into the nucleus. Topical application of 4-O-methylhonokiol (0.1–1 mg/ear) inhibited 12-O-tetradecanoylphorbol-13-acetate-induced inflammatory ear edema formation, NF-κB activity, and iNOS and COX-2 expression. The present results provided evidence that 4-O-methylhonokiol has anti-inflammatory properties through inhibition of the NF-κB pathway, and suggested that 4-O-methylhonokiol can be used as an anti-inflammatory agent.Chemico-Biological Interactions 12/2010; 188(3):677-677. · 2.98 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Peroxisome proliferator-activated receptor (PPAR)-gamma agonists such as troglitazone, pioglitazone and thiazolidine have been shown to induce apoptosis in human colon cancer cells. The molecular mechanism of PPARgamma agonist-induced apoptosis of colon cancer cells, however, is not clear. Glycogen synthase kinase-3beta (GSK-3beta) is an indispensable element for the activation of nuclear factor-kappa B (NF-kappaB) which plays a critical role in the mediation of survival signals in cancer cells. To investigate the mechanisms of PPARgamma agonist-induced apoptosis of colon cancer cells, we examined the effect of troglitazone (0-16muM) on the activation of GSK-3beta and NF-kappaB. Our study showed that the inhibitory effect of troglitazone on colon cancer cell growth was associated with inhibition of NF-kappaB activity and GSK-3beta expression in a dose-dependent manner. Cells were arrested in G(0)/G(1) phase followed by the induction of apoptosis after treatment of troglitazone with concomitant decrease in the expression of the G(0)/G(1) phase regulatory proteins; Cdk2, Cdk4, cyclin B1, D1, and E as well as in the anti-apoptosis protein Bcl-2 along with an increase in the expression of the pro-apoptosis-associated proteins; Caspase-3, Caspase-9 and Bax. Transient transfection of GSK-3beta recovered troglitazone-induced cell growth inhibition and NF-kappaB inactivation. In contrast, co-treatment of troglitazone with a GSK-3beta inhibitor (AR-a014418) or siRNA against GSK-3beta, significantly augmented the inhibitory effect of troglitazone on the NF-kappaB activity, the cancer cell growth and on the expression of G(0)/G(1) phase regulatory proteins and pro-apoptosis regulatory proteins. These results suggest that the PPARgamma agonist, troglitazone, inhibits colon cancer cell growth via inactivation of NF-kappaB by suppressing GSK-3beta activity.Chemico-biological interactions 10/2010; 188(1):75-85. · 2.46 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Amyloid beta (Abeta)-induced neurotoxicity is a major pathological mechanism of Alzheimer disease (AD). In this study, we investigated the inhibitory effect of l-theanine, a component of green tea (Camellia sinensis), on Abeta(1-42)-induced neuronal cell death and memory impairment. Oral treatment of l-theanine (2 and 4 mg/kg) for 5 weeks in the drinking water of mice, followed by injection of Abeta(1-42) (2 microg/mouse, icv), significantly attenuated Abeta(1-42)-induced memory impairment. Furthermore, l-theanine reduced Abeta(1-42) levels and the accompanying Abeta(1-42)-induced neuronal cell death in the cortex and hippocampus of the brain. Moreover, l-theanine inhibited Abeta(1-42)-induced extracellular signal-regulated kinase (ERK) and p38 mitogen-activated protein kinase as well as the activity of nuclear factor kappaB (NF-kappaB). l-Theanine also significantly reduced oxidative protein and lipid damage and the elevation of glutathione levels in the brain. These data suggest that the positive effects of l-theanine on memory may be mediated by suppression of ERK/p38 and NF-kappaB as well as the reduction of macromolecular oxidative damage. Thus, l-theanine may be useful in the prevention and treatment of AD.Free Radical Biology and Medicine 09/2009; 47(11):1601-10. · 5.27 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Sulfur compounds isolated from garlic exert anti-inflammatory properties. We recently isolated thiacremonone, a novel sulfur compound from garlic. Here, we investigated the anti-inflammatory and arthritis properties of thiacremonone through inhibition of NF-kappaB since NF-kappaB is known to be a target molecule of sulfur compounds and an implicated transcription factor regulating inflammatory response genes. The anti-inflammatory and arthritis effects of thiacremone in in vivo were investigated in 12-O-tetradecanoylphorbol-13-acetate-induced ear edema, carrageenan and mycobacterium butyricum-induced inflammatory and arthritis models. Lipopolysaccharide-induced nitric oxide (NO) production was determined by Griess method. The DNA binding activity of NF-kappaB was investigated by electrophoretic mobility shift assay. NF-kappaB and inducible nitric oxide synthetase (iNOS) transcriptional activity was determined by luciferase assay. Expression of iNOS and cyclooxygenase-2 (COX-2) was determined by western blot. The results showed that topical application of thiacremonone (1 or 2 microg/ear) suppressed the 12-O-tetradecanoylphorbol-13-acetate-induced (1 microg/ear) ear edema. Thiacremonone (1-10 mg/kg) administered directly into the plantar surface of hind paw also suppressed the carrageenan (1.5 mg/paw) and mycobacterium butyricum (2 mg/paw)-induced inflammatory and arthritic responses as well as expression of iNOS and COX-2, in addition to NF-kappaB DNA-binding activity. In further in vitro study, thiacremonone (2.5-10 microg/ml) inhibited lipopolysaccharide (LPS, 1 microg/ml)-induced nitric oxide (NO) production, and NF-kappaB transcriptional and DNA binding activity in a dose dependent manner. The inhibition of NO by thiacremonone was consistent with the inhibitory effect on LPS-induced inducible nitric oxide synthase (iNOS) and COX-2 expression, as well as iNOS transcriptional activity. Moreover, thiacremonone inhibited LPS-induced p50 and p65 nuclear translocation, resulting in an inhibition of the DNA binding activity of the NF-kappaB. These inhibitory effects on NF-kappaB activity and NO generation were suppressed by reducing agents dithiothreitol (DTT) and glutathione, and were abrogated in p50 (C62S)-mutant cells, suggesting that the sulfhydryl group of NF-kappaB molecules may be a target of thiacremonone. The present results suggested that thiacremonone exerted its anti-inflammatory and anti-arthritic properties through the inhibition of NF-kappaB activation via interaction with the sulfhydryl group of NF-kappaB molecules, and thus could be a useful agent for the treatment of inflammatory and arthritic diseases.Arthritis research & therapy 09/2009; 11(5):R145. · 4.12 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Alzheimer's disease (AD) is characterized by the extracellular deposition of beta-amyloid peptide (Abeta) in cerebral plaques. Abeta is derived from the beta-amyloid precursor protein (APP) by the enzymes alpha-, beta- and gamma-secretase. Compounds that enhance alpha-secretase, but inhibit beta- or gamma-secretase activity, have therapeutic potential in the treatment of AD. Green tea, or its major polyphenolic compound, has been shown to have neuroprotective effects. In this study, we investigated the possible effects of (-)-epigallocatechin-3-gallate (EGCG) on memory dysfunction caused by Abeta through the change of Abeta-induced secretase activities. Mice were pretreated with EGCG (1.5 or 3 mg/kg body weight in drinking water) for 3 wk before intracerebroventricular administration of 0.5 microg Abeta(1-42). EGCG dose-dependently reduced the Abeta(1-42)-induced memory dysfunction, which was evaluated using passive avoidance and water maze tests. Abeta(1-42) induced a decrease in brain alpha-secretase and increases in both brain beta- and gamma-secretase activities, which were reduced by EGCG. In the cortex and the hippocampus, expression of the metabolic products of the beta- and gamma-secretases from APP, C99, and Abeta also were dose-dependently suppressed by EGCG. Paralleled with the suppression of beta- and gamma-secretases by EGCG, we found that EGCG inhibited the activation of extracellular signal-regulated kinase and nuclear transcription factor-kappaB in the Abeta(1-42)-injected mouse brains. In addition, EGCG inhibited Abeta(1-42)-induced apoptotic neuronal cell death in the brain. To further test the ability of EGCG to affect memory, EGCG (3 mg/kg body weight) was administered in drinking water for 1 wk to genetically developed preseniline 2 (PS2) mutant AD mice. Compared with untreated mutant PS2 AD mice, treatment with EGCG enhanced memory function and brain alpha-secretase activity but reduced brain beta- and gamma-secretase activities as well as Abeta levels. Moreover, EGCG inhibited the fibrillization of Abeta in vitro with a half maximal inhibitory concentration of 7.5 mg/L. These studies suggest that EGCG may be a beneficial agent in the prevention of development or progression of AD.Journal of Nutrition 09/2009; 139(10):1987-93. · 4.23 Impact Factor
Publication Stats
352 | Citations | |
99.37 | Total Impact Points | |
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Chungbuk National University
- College of Pharmacy
Chinsen, North Chungcheong, South Korea
Korea National University of Transportation
- Department of Food Science and Food Technology
Seoul, Seoul, South Korea


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You may have heard the phrase "panic attack" or "panic disorder" before. But you may be left wondering: What is a panic attack? If you've experienced one of these attacks or think you may be experiencing them, you know how frightening they can be. Other people may be worried for you at first then become frustrated and blame you for the condition. Once you understand panic attacks better you can help others learn what is happening to you. Learning First Hand " What is a Panic Attack? " One long-term sufferer of panic attacks described her first attack as "an intense feeling that I was about to die." She recalled sitting in a darkened movie theater surrounded by her family and suddenly feeling a tightening in her chest that she believed was a sign of a heart attack. She couldn't breathe. As soon as the movie ended, she had her family take her to the emergency room where she was diagnosed as being perfectly fine. This is not an unusual story for people who suffer from panic attacks. The attacks bring on a series of physical sensations – often similar to those described for a heart attack – but which are triggered by the body's own flight or fight response system. Usually, the system responds to fearful situations but in the case of a panic attack, the trigger is usually nothing frightening at all and might be something as simple as the fear of having another attack. So what is a panic attack? The same type of reaction you might have to have life threatening situation but in a situation that could be as harmless as watching a movie, having dinner at a restaurant, or sleeping. The APA Diagnosis According to the American Psychological Association (APA), the answer to the question "What is a panic attack?" includes three criteria besides the physical symptoms: • The attack must happen suddenly As many as 4 million people in the United States may have suffered from at least one or two panic attacks in their life. For those who suffer from repeat or frequent panic attacks, the condition is elevated to panic disorder. People who have panic disorder and who do not receive proper treatment can continue having worsening panic attacks and can even develop full-blown social phobias. Taking the Right Steps If you think you have had or are having a panic attack, your first stop should be your doctor. The symptoms of these attacks are similar to those of serious health problems that might require immediate medical attention. You need to rule that out before deciding you're only having a panic attack. Once you've ruled out health problems as the cause for your condition, you may need to speak to a mental health professional about the attacks so you begin receiving appropriate treatment. They can also help you further understand what is a panic attack. By: D. More Suffering from Panic Attacks is pure hell — I know! seconds. Reclaim Your Freedom Now by visiting: http://AnxietyPanicFreeZone.com Technorati Tags: cure panic attacks, overcome panic attacks, panic attack, panic attacks, Stop Panic Attacks |
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Hotel Airport Tirana
- Shuttle bus service
- Continental Breakfast
- Suites
- Free High-Speed Internet
- Restaurant
- Swimming pool
TripAdvisor Reviews Hotel Airport Tirana
Travel Blogs from Tirana
Tirana (Albania), Montenegro and Dubrovnik
... solely a concrete shell then they only had 1 small portion of 1 floor that looked like it was lived in with the other floors remaining empty concrete shells. Reinforcing bars sticking up all over the show indicating the thoughts of future enlargement but they just haven't gotten quite that far yet. The Albanians also sound like a superstitious bunch with teddy bears and dolls hanging from some ...
Tirana International Film Festival
... do was fill out some information and pay the visa fee ($60US!!) and they emailed the visa straight to us! So easy! When all that was done and we'd finished eating, we went for a walk in a random direction that we hadn't been yet and found ourselves in a market full of clothing stores. We had a bit of a look around and Darren bought some new undies then we headed back to the hostel for jumpers, before we were planning to go back to the film festival. ...
We're in Albania, yo!
... another tour was showering - gust of wind a lot of pale skin... enough said, I never want to speak of it again! ha Not sure if I've mentioned that Greece doesn't have a great sewerage system, and used toilet paper can not be flushed but, instead, is placed in a bin next to the toilet. Not sure why, but these bins are comparable in size to itty bitty bins!!? Imagine having the job of emptying those every 5 minutes!! The reason I may be mentioning this again is that I am ...
Farewell to the mountains
... we took a small side road instead of the right one. This led us down to a valley, from where the only way out was on the motorway. (We could also have returned the same way but the road was steep and in very bad condition so we wouldn't have got too far before sunset.) It was not an easy decision even though in Albania it is common practice to cycle on any road and the traffic was very low. Actually, I had to use all my negotiation skills ...
... construction just sitting. The whole way if I had taken a photo every 30 seconds going down the road you would see half-finished places – it is quite depressing. On the way from Montenegro to Tirana where we are staying tonight we went over the hills on a back road rather than take the motorway. This was an interesting drive to say the least. There are no road rules here ...


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Barack Obama with Britney Spears' body? Oh, it happened (PHOTOS) by Julie Sprankles Dec 19, 2014 Share Tweet Pin Share Save Britney Spears' Women's Health cover has been generating a ton of buzz this week — largely because many people are dubious it is Brit. Read Full Story
Nicolas Cage explains why he still feels like an outsider by Cailyn Cox Sep 23, 2014 Share Tweet Pin Share Save Nicolas Cage is notoriously private, so when he finally agrees to do an interview it's an exciting moment to finally be let inside the workings of his mysterious mind. Read Full Story
Resurrection, The Leftovers, and now Left Behind: Is Hollywood convinced the end is near? by Tiffany Antone Aug 06, 2014 Share Tweet Pin Share Save The recent spate of apocalyptic projects coming out of Hollywood has us wondering if they know something we don't. Read Full Story
VIDEO: Nicolas Cage as Superman? It almost happened by Tiffany Antone Jul 25, 2014 Share Tweet Pin Share Save Here are four names we never thought we'd hear put together for a movie pitch: Kevin Smith, Tim Burton, Nicolas Cage and Superman. Roll those together for your elevator pitch, and we'd be begging you to take our money. Yet, somehow, this fantastic cocktail of creative strangeness was never realized, and now someone is making a documentary all about why not. Read Full Story
Naya Rivera and other stars who married quickly by Kat Trofimova Jul 23, 2014 Share Tweet Pin Share Save Celebrities really do love getting married, eh? Naya Rivera married Ryan Dorsey only three months after ending her engagement to Big Sean. But she's not alone! Read Full Story
Nicolas Cage: Just call him grandpa by Kristyn Burtt Jul 03, 2014 Share Tweet Pin Share Save It's hard to believe that some of our favorite action stars are now old enough to be grandparents. That's exactly what happened to Nicolas Cage on Tuesday, July 1. Read Full Story
7 Celebrities with surprisingly exotic pets by Julie Sprankles Jun 13, 2014 Share Tweet Pin Share Save While most people are content to cuddle up with a kitten or play fetch with a puppy, some celebs opt to bring decidedly more exotic pets into their homes. From Justin Bieber's capuchin monkey to Kristen Stewart's wolves, you might be surprised by these celebrity companion animals. Read Full Story
Mighty Morphin Power Rangers movie dream cast by Tiffany Antone May 08, 2014 Share Tweet Pin Share Save The Mighty Morphin Power Rangers is set to return to the big screen, and we've got our dream cast all picked out. Read Full Story
Jonah Hill and other low-paid Hollywood actors by Kat Trofimova Jan 22, 2014 Share Tweet Pin Share Save Jonah Hill confessed to working on The Wolf of Wall Street for only $60,000! We've rounded up a few other actors with shockingly low movie salaries. Read Full Story
Nicolas Cage's steamy sex photos have been stolen! by Cailyn Cox Nov 13, 2013 Share Tweet Pin Share Save Nicolas Cage's headache continues. Steamy sex photos with ex-girlfriend Christina Fulton are still missing and while the potential culprit has been caught, there's still no sign of the illicit snaps. Read Full Story


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Dr. Sunil K. Gallapalli, MD
Internal Medicine, Medical Group Of The Carolinas Inpatient Medicine
- 101 E Wood St
Spartanburg, SC 29303 - 1 Office Location
- (864) 560-6619
Dr. Sunil K. Gallapalli graduated from the Rangaraya Med Coll, Vijayawada Univ Hlth Sci, Kakinada, A P, India in 2002. He works in Spartanburg, SC and specializes in Internal Medicine. Dr. Gallapalli is affiliated with Spartanburg Regional Medical Center. He speaks English and Spanish.
Gender: Male
Years in Practice: 13 Years
Languages Spoken: English, Spanish
Medical School: Rangaraya Med Coll, Vijayawada Univ Hlth Sci, Kakinada, A P, India
Graduation Date: 2002
Hospital Affiliations: Spartanburg Regional Medical Center
Specialties: Internal Medicine


text: Danica Patrick By Jon Ledford January 24, 2014 6:27 PM | TheFW Share on Facebook Share on Twitter Source: Danica Patrick Category: Share on Facebook Share on Twitter More Leave a comment Send to a friend! Print this page Pin it! Reddit This! Share on Tumblr! More from KIX 105 Eat Well and Help Local Kids With Chili and Soup Cookoff for Boy Scout Troop 66 [INTERVIEW] Danielle Bradbery Enjoys Sports, The Excitement of Football Season Album Spotlight: Eric Church 'The Outsiders' – ToC Critic's Pick Enquiring Minds: Valentine's Day Gifts [SURVEY] Best of the Web


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This will be contrast the water only show in the Highveld until we return in 2013. We are once again going on the road in the begining of May, as we have had a recall to the USA for this years summer circuit. We hope to see you all there, as we share a night of Death Metal with you, and our very, very special guests Bleeding Spawn.
Sounds Like: Cannibal Corpse, Pantera, Dying Fetus, Napalm Death, Divine Heresy
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Bio: Contrast The Water Began in 2006 spending hours practising above the Winston Pub in Durban. with line up changes and a release of a debut album the band as well as having the opening for some big international metal bands has grown to be one of the well supported metal bands in South Africa and ...See Full Bio
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Wise Quotes, Wisdom Sayings - Page 39
If you have nothing good to say to a person just don't say it.
If you call yourself a "master", stop asking people if you think you should! "Masters" must 'know' what to do!
If you're not going to risk one thing, you'll never risk and gain anything.
Nobody has the right to judge anyone, cause then we would have to judge ourselves, and we are our own worst critics.
Ambitious people, have a sense of direction in life, definitely work diligently to bring about success, creative thinking and well thought out plan, always growing in knowledge and acknowledging wisdom. Be the head or the leader of your great work and never a follower into a procrastinator or empty misleading followers.
– Jean- Claude Jennings
Without struggle there is no progress.
Invest your time wisely, it pays off in the future.
When you have to make hard decision, flip a coin.
Why? Because when that coin is in air, you suddenly know what you're hoping for.:)
Trying to be the best amongst the rest doesn't speak the best about you as with trying to be the best of your own self.
May your successes bring you courage and your failures bring you wisdom.
Like father like son.
Some people feel like they don't deserve love. They walk away quietly into empty spaces, trying to close the gaps of the past.
If we admit that human life can be ruled by reason, then all possibility of life is destroyed…
What if I were smiling and running into your arms? Would you see then what I see now?
I don't understand why people, why every single person is so bad to each other so often. It doesn't make sense to me. Judgment. Control. All that, the whole spectrum.
^^^ quotes from the movie "Into the wild".
Maybe it's not about the happy ending. Maybe it's about the story.
The past is practice.
Even the best fall down sometimes.
Wake up every morning with the thought that something wonderful is about to happen.
Always be thankful for what you have, because you can always have less.
That moment when you put a pot on the stove to boil…and realize you forgot the water.
Why be nice to people who have done wrong to you? Because you're not like them.
Courage is fire, and bullying is smoke.
Everyone's a star, but it's their choice whether they want to shine or not.:)
Nothing is cheap, nothing is expensive. People say it's expensive because they have little in their pockets, and they say it's cheap because they have more than enough in their pockets.
Hope for good, but prepare for the worst.
The one- eyed man doesn't thank God until he sees a blind man.
Never use 'always' or 'never' because 'never' and 'always' are absolutes and absolutes will get you into trouble.
We are all born into this world as nothing more than a lump of clay, but it takes the hands of learning and life to mold us.
Everyone has an equal chance, it's the ones who take it that are the lucky ones.
Never regret a word you say, because you meant every word you said, just the result of it is was not what you were expecting.


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Make Your "Five-Oh" Go Faster and Smoother
Learn how to pump up the volume in your pony.
It's a long way from Detroit to Milan, but Hudson's attempt to bridge that gap was nothing less than amazing.
V-8 power makes this the best C1 ever.
In just a few short years, Walter P. Chrysler took his company from an unknown automotive manufacturer to fourth in the industry, with...
Giving a 1927 Chrysler a really personal touch...and 3,000 rivets.
Dodge's assembly plant on Monroe Street was a testament to the highs and lows of the American automobile industry.
Putting a unique grille on your hot rod, rat rod, or custom is easier than you think.
Ford was just ramping up production of their new 1942 models when World War II rerouted production for a greater cause.
A peek inside "Flatjack" Jack Meyer's amazing flathead Ford collection.
Mustang's third body style emerges.
Giving credit to the man who many consider the reason for the Corvette's long lasting success.
We've picked 11 classics, built between 1965 and 1998 that we feel offer a great blend of style, individuality, performance and some cases,...
Upgrading a 1966 Mustang's Baer system from two-piston PBR caliper to six-piston Baer caliper.
After a light refresh Roger Moore's "other" spy car is ready to take to the screen again.
After four decades of slumber one of Zagato's finest creations returns to the limelight.
We pick what we think are the five best Lamborghinis ever.
A Fifties Lexicon
If not for the Corvette Sebring Racer, the life of the Corvette may have been a brief one.
Watch as the experts from Steele Rubber Products show you how to replace these often forgotten but very important window seals.
Watch as the experts from Steele Rubber Products show you just how quick and easy it can be to remove and replace your trunk seal.
Watch as the experts from Steele Rubber Products show you how to replace the door seals on a Ford truck.
Watch as the experts from Steele Rubber Products show you how to remove and replace the often overlooked bumpers that keep your hood and...
Lancia turned the docile Delta into a rip-snorting racing machine.
From normal hatchback to fierce racer, here are the highlights of the Lancia Delta Integrale story.
New Power For Old Iron
Proceeds From Sale of Car to Benefit Alliance of Auto Artisans
Utility and style meet with these great wagons.
We Interview Fast Five's Car Coordinator Dennis McCarthy
The true root of the hobby, these hot rods hit the jackpot.
Just because an engine lives under the hood doesn't mean it can't be beautiful.
A fitting finale for an amazing Ford filled event!
These high-dollar machines are right at home in Las Vegas.
A car guy's confession to not so temporary insanity.
AutoTrader.com Employees Show Off Their Rides!
New car plus old styling equals retro cool!
Are these cars the next great collectibles? Only time will tell...
AutoTrader Classics Editor Brian Medford travels to Streetside Classics in Powder Springs, GA to talk about the 2002 Camaro.
A quick sneak peak at the big show!
No more explanation needed, these are just some cool rides.
Classic cars invade downtown Atlanta.
Do horses of a feather flock together?
Steel may be real, but fiberglass has class!
Our Editor Brian Medford picks his favorite cars of the show.
These designers dared to be different.
Things are moving fast at the site of the south's newest raceway.
From horseless carriages to speedsters, these rolling masterpieces captured everyone's imagination.
Magnificent examples of living automotive history!
America's home grown sports car had a great showing at this year's concours.
Just a few of the cars you can find only on AutoTrader Classics.
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AutoTrader Classics Editor Brian Medford travels to Streetside Classics in Powder Springs, GA to talk about one of his favorite cars, the Impala SS.
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They will be handed over to Forest Department
Customs Air Intelligence officials seized 295 live star tortoises from a Kuala Lumpur-bound passenger at the Tiruchi airport on Thursday.
Intelligence received
Acting on specific intelligence, they intercepted Ahamed Sirajudeen (47) of Chennai, when he was about to board a Sri Lankan Airlines flight to Colombo on way to Kuala Lumpur.
Concealed in bags
An examination of the passenger's check-in baggage revealed the star tortoises concealed in six cloth bags kept inside a stroller bag.
The contraband was seized under the provisions of the Customs Act, 1962 read with the Wildlife Protection Act, 1972.
Protected species
Star tortoises are protected under Schedule IV of the Wildlife Protection Act, which bans their possession and transfer in any form for commercial use.
It is also protected under the Convention on International Trade in Endangered Species, to which India is a signatory.
Sources in the Customs Department said that investigations revealed that a person in Chennai is believed to have arranged for the illegal export of the tortoises through Ahamed Sirajudeen.
The seized tortoises and the passenger will be handed over to officials of the Forest Department for futher action.
Keywords: star tortoises, Customs Act, wildlife protection


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Document Type: | Book |
All Authors / Contributors: |
Thomas Henry Foster; Torch Press. |
OCLC Number: | 8944116 |
Description: | 72 pages, [4] leaves of plates : illustrations ; 22 cm |
Contents: | The unbought grace of life -- A businessman looks at books and literature -- The pleasures of collecting bookplates -- The humanities in a world of uncertainties. |
Other Titles: | Essays. |
Responsibility: | by Thomas Henry Foster ; with a foreword by Lawrence Oakley Cheever. |
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Half Year Cheer!
We are gearing up for Half Year Cheer (aka All-Star Prep). If your season with high school, pop warner cheer or another sport is ending, consider Half Year Cheer. This would be a great opportunity for those of you that have thought about joining an all-star cheer team but aren't sure. It is less expensive, the competitions are local and you will still get to train with experienced all-star coaches. Practices begin November 1. If interested, contact Gaby at firstname.lastname@example.com or give us a call, (916) 873-0735. Also follow us on Facebook at Royal Allstar Cheer - News.
Get Ready, Set, Cheer!
If you have thought about cheerleading but were too afraid to put on the uniform, we are looking for you. If you didn't make your high team, no worries, experience necessary, we will train you. We like building our own athletes.
If you have experience, we want your skills. We have a team for everyone and we offer skill discounts. Come to our family where you will be treated like Royalty.
Open Gym Mondays!
Open gym is on Mondays. Why not start out your week with us. Come out and practice a skill, just come and have fun with us 8:30 to 10:30p, $2 for Royalty and $4 for friends.
Tumbling Program
Checkout our tumbling program, we have a class for everyone. We even have a Tiny Tumbler program for 3-5 year olds. Tumbling classes are included in the youth to senior cheer program at no extra cost for our athletes. For more information, contact our office (916) 873-0735 or email us at firstname.lastname@example.com. You will find a comprehensive list of classes on our website. Our instructors also offer private sessions.


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Video: Sharing the load with Zach
Zach Sobiech, 18, of Lakeland passed away Monday morning, May 20, 2013, of a rare bone cancer. He spent his last months with friends, family and his girlfriend, Amy Adamle of Woodbury. "She's strong enough to share the load with me," Zach said. "It's unbelievable. She knows how to say things in a way that fixes everything."
Video by Ben Garvin, Pioneer Press
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Kids are now able to go to school because of available transportation. (Photo courtesy of Philippine Funds for Little Kids)
On January 20, 2012, I was invited to speak at TEDxMontpellier in southern France. There, I shared my experience in using social media to bring about social change in the Philippines — particularly about my experience in building up the Philippine Funds for Little Kids (or as it is popularly known, the Yellow Boat Project).
It's been an exciting journey for us over the last 16 months since I first found out about the story of the kids who have to swim just to be able to get to school in the mangrove village of Layag-Layag in Zamboanga City. We gave the first yellow boat last March, and we have since expanded into three communities, namely Layag-Layag, Bgy Talon-Talon, Zamboanga City; Isla Mababoy, Bgy Guinhadap, Monreal, Masbate; and Lakewood, Zamboanga del Sur.