text:
I think I've made it pretty clear that in general, I'm not one for politics. Of course, like anyone else, when politics start to encroach on my everyday life and business, that changes. Internet freedom is someone we've discussed here before and it's a subject that for most of us, hits directly home both personally and financially.
Freedom, fundamentally, requires that everyone must have it or none will. So if you and your neighbours are free, but your fellows the next town over aren't, then you aren't really free either. Whomever took the freedom from those next to you will surely attempt to take yours. The Internet is global and thus, if the entire Internet is not free of censorship and tyranny, then none of it is. Sure, it may not hurt you or I if they block certain sites or suppress certain types of speech in Iran or China, but those small chinks in Internet freedom's armour mean that, eventually, someone will get the idea to do it here too.
Currently, despite being the world's largest democracy, India is seeing some decided non-democratic censorship online. Websites like Vimeo (the video sharing site) are blocked from use in India and activists are finding their web blogs and websites being seized and closed. To their credit, Indians aren't just sitting back and watching and have staged protests and hunger strikes to promote Internet freedom.
In China, where much of the Internet is inaccessible thanks to government firewalls, an active underground industry of hackers and activists routinely circumvent those blockades and get out to the world anyway – bringing some of the world back in with them when they return. In Iran, Saudi Arabia, and other places that have restrictions on what can be accessed online, the same phenomenon happens.
'But those are faraway places,' many people would say. 'They aren't Canada. They aren't the USA.'
Sure. Not yet, anyway.
But Internet freedom is being challenged here as well. A few months ago, 'SOPA' was all the rage in the news as activists and pundits went back and forth about whether or not this legislation would have helped or hindered, destroyed or bolstered freedom. Even I said a few words about it. Most people believe that with the demise of that and similar legislation, things are now well and good.
Except they aren't. Things are still happening. Rumbles, grumbles, mentions, little amendments here and there in Washington and Ottawa. Although freedom of speech in our countries is largely open and unrestricted, there are those who want to change that. Their primary target is the Internet.
Why? Because it's been the single most connecting and prolific source of political turmoil and paradigm change since the telephone. More than television, phones, radio, or any other communications medium, the Internet has fundamentally altered how we as humans interact and share information. For people who crave power and control, this is not a good thing.
So they seek to stop it.
I'm not going to tell you that you should get active or call your elected representatives. I'm just telling you that if the Internet doesn't remain open and free, then we'll lose the single greatest tool we have for exercising our own freedom of speech and the best way we have of freely communicating without restriction or restraint. The only people who fear the Internet's open communications are those who fear freedom and want to control it. Beware of those people.


text:
Kofax Optimizes Enterprise Capture Platform with Enhanced Capabilities
Kofax, a provider of capture driven process automation solutions, recently announced that it was extending its enterprise capture platform by adding powerful new capabilities which will help users to manage critical information across their enterprises more effectively.
Now that Kofax has extended its high volume capture capabilities, customers will now not only have a robust process for safely capturing all types of inbound information but will also be able to immediately extract and validate the accuracy of information on which their organization thrives. Kofax's new capture driven process automation solutions will boost productivity levels, reduce operation costs and errors that are normally associated with manual tasks, as well as improve the overall quality of information.
In a release, Jim Nicol, Executive Vice President of Products at Kofax, said, "Our market leadership and global customer base are proof that Kofax's capture driven process automation solutions deliver the most scalable and powerful software available. These new capabilities make Kofax's market leading solutions even easier to leverage across the enterprise. Administrators can ensure high user success through more customized features as well as expand complete capture capabilities to any input source, in any location and to any destination. These capabilities reduce the costs associated with training and support and increase efficiency and productivity across the enterprise."
Some of the new and improved features of Kofax capture driven process automation solutions include:
- Browser-based deployment where Kofax Capture modules can now be deployed and operated within the browser, enabling scanning, indexing, validation and overall operations to function within a thin client environment, significantly reducing deployment costs;
- User centric interface where capture operations will now extend into front office, customer facing processes at remote branch locations and new departments within an organization, a standardized, intuitive user interface is vital for ensuring ease of use while reducing training and support costs;
- Expanded customization tools that offer improved filtering and search capabilities, as well as enhanced workflow capabilities and expanded application programming interfaces (APIs) allow administrators to customize and prioritize applications; and
- Expanded language packs that allow client facing applications to run in the user's preferred language.
Want to learn more about the latest in communications and technology? Then be sure to attend ITEXPO West 2011, taking place Sept. 13-15, 2011, in Austin, Texas. ITEXPO (News - Alert) offers an educational program to help corporate decision makers select the right IP-based voice, video, fax and unified communications solutions to improve their operations. It's also where service providers learn how to profitably roll out the services their subscribers are clamoring for – and where resellers can learn about new growth opportunities. To register, click here.
Carolyn John is a Contributor to TMCnet. To read more of her articles, please columnist page.
Edited by John Lahtinen

subset: commoncrawl


text:
SVT Group and AVPN have come together to produce a guide for venture philanthropists and social investors for impact measurement in Asia. Organisations that contributed to the report with regards to their approaches include AVPN members: Dasra, Insitor Fund, LGT Venture Philanthropy, Social Ventures Australia and Social Ventures Hong Kong.
Download the full report here.


text:
Girlie Night
PITCH PERFECT Sing-Along
Director | Jason Moore |
Year | 2012 |
Starring | Anna Kendrick, Rebel Wilson, Skylar Astin |
Rating | PG-13 |
Run Time | 112min |
Age Policy |
18 and up; Children 6 and up will be allowed only with a parent guardian. No children under the age of 6 will be allowed. |
More Info | IMDb |
Are you ready to get pitch-slapped? Join us for an aca-awesome and totally interactive screening of PITCH PERFECT!
Girlie Night and the Action Pack have teamed up to bring you a night where making music with your mouth isn't just encouraged, it's downright mandatory. We've subtitled all of your a capella lady jams, so you can sing-along with the Barden Bellas and the Treblemakers, as well as all of your favorite quotes, because we're Dixie Chick serious about loving this movie.
We'll also have special plastic cups for everyone so you can try to be as talented as Anna Kendrick (good luck with that). And, as long as you're not the cookie-tossing Aubrey type, you're encouraged to compete in our live riff-off before the movie for a chance to win a totally fake replica of the microphone that Hoobastank used when they rocked the performing arts center!
So start practicing your harmonies and your mermaid dancing, but leave those lame sock puppets at home, because we're heading to nationals, bitches. Aca-believe it! (Sarah Pitre)


text:
Sounds great! Hope you had a magical time!
Arrival Night/Check In
My 2 friends, Catherine (cat) & Christy left work at 4:30 pm Wednesday afternoon heading to Disney World. Not much traffic at all. We arrived just after midnight.
We checked into the All Stars Music with no problem. However, once we arrived at our room (which was in Calypso) we noticed the door was open (hmmmm). We walked in thinking maybe the guy bringing the fridge just didnt shut the door good, but there was no fridge & the TV station/dresser was in the middle of the room. Then we noticed the bed was a King sized & not 2 doubles. I called the front desk to see what we could do. Keep in mind this was after we trucked all of our luggage & stuff to the room. Brice- a great CM at the front desk sent a CP to our aid with a luggage cart & room keys for our new room which was now located in building 7. It was a LOT further from the lobby/bus loading area, but it had two double beds, so we had to take it. There was still no fridge. At this point, were all getting really tired since its now after 2 am! I call Brice again to inquire about the fridge & he said the guy should be bringing it any minute. And of course about 10 minutes later the guy showed up. He was not the friendliest CM at Disney, but I guess if I were delivering fridges at 3 in the morning I might be grumpy too.
We all hit the hay & prepared to wake early for our first day at Disney!
Thursday, April 21, 2005 Blue skies, warm temps with light breeze.
Magic Kingdom
Grand Entrance:
I really wanted to make it to the park before opening since it was Christys first trip EVER to WDW! We arrived about 20 minutes before the park opened. We were greeted by Mickey :mickey: as he opened the gates to the Magic Kingdom. We headed straight to the hat shop to get Christy & Cat their mouse ears. (I of course, already had mine). We made our way through the candy store but before stepping on Main Street, I had Christy close her eyes. I led her to the middle of the street & said, Open. It was her first view of the castle & I could tell by the look on her face she was immediately hooked! We said Hello to the Mayor as we passed & waved to the Dapper Dans on the trolley.
Adventure Land:
We crossed the bridge into Adventure Land & immediately noticed the park was not very crowded at all! We climbed The Swiss Family Robinson Tree House, took a few pictures, & climbed down heading for Aladdins Carpets. After our quick spin around Agrabah we of course went to visit my friends, the Pirates of the Caribbean! We all loved it! (duh!) Since Jungle Cruise & the Tiki Room were both closed till 10, we went into Frontier land to hit a couple of Floridas famous mountains!
Frontier Land:
Since there was no line at either mountain, we jumped on Big Thunder Mountain to get our blood flowing! After a crazy ride through the mining mountain, we headed south for some slipping falls fun! Again, there was no line at all. I think we waited about 7 minutes for our log. Christy & I sat up front & of course got soaked! That was ok though since the weather was really nice! We were walking around Lou land I mean Frontier Land just taking in the sights & sounds when Christy sees Woody! She runs up & jumps in line to get his autograph (it wasnt a stamp either- he actually signed his name!) She was too cute!
Since it was after 10:00, we ran back to Adventure land for the Jungle Cruise & the Tiki Room! (again no long lines)
Liberty Square:
Ok, by now, the park is starting to get a little crowded. We make our way to the Haunted Mansion & get in line. It says there is a 25 minute wait (actually only about 10). We decide to run grab a couple of waters & eat lunch. We packed our sandwiches & chips so we just decided to feast while waiting in line. What a great way to save time! (Not to mention money!!!) We were all 3 in one doom buggy & my mouse ears were scraping the top making a really creepy noise! I pointed out some hidden secrets to Christy while in there (the plate HM was not in place). After the hitchhiking ghost ran us out of the manor, we decided to hit Fantasy Land (YAY!)
Fantasy Land:
The first thing we did was hop on a boat for the happiest cruise that ever sailed! It was so pretty in there! It just looked a lot brighter than before. Of course we all 3 came out singing (no surprise there). Then we went on an Adventure with Snow White, took a spin on the teacups, rested our feet for Mickeys PhilarMagic, rode the carousel, & finally took flight with Dumbo! That was probably the longest line so far. It was about a 20 minute wait.
Mickeys Toon Town Fair:
After Dumbo landed, we had to go see Mickey!!! We visited Minnies house, then Mickeys & of course went to see him at the Judges tent! Christy also met Tigger , Eeyore & Pooh for the first time! We left toon town heading for Tomorrow land
Tomorrow Land:
Before hitting tomorrow land, we bought a pretzel in Fantasy Land & went to get some hot cheese from the Starlight Café, but they didnt have any! We waited for about 25 minutes for hot cheese, but we finally just had to eat our pretzel cold & plain. (sigh).
After our cold snack, we went for a drive along the speedway. While waiting in line, we noticed a little girl spitting on the drivers from the ramp. We yelled at her to stop. She got embarrassed & turned around. She then spit from the other side! How Gross!!! Way to watch, mom! Anyway We got fast passes for Buzz & hit the line for Space Mountain. We waited about 35 minutes for our rocket. After SM, we decided to give Stitch a try. I can not believe he burped that nasty chili dog breath in our faces! It was so gross I thought I was going to gag! I did not smell that last time I was there! GROSS!!! Anyway after groddy ol Stitch, we relaxed for a few minutes on the TTA! Then it was on to Buzz Lightyears Space Ranger Spin. I was in a car by myself so I could steer & shoot. Well, the ride broke down a couple of times & believe it or not I got 999,999 points!!! I was so excited!!! I hit a couple of key targets up front so I started out with more than 100,000 points! I usually loose, so I was thrilled at the high score!
We decided to grab a bite to eat & find a place for the Spectromagic parade & Wishes. We ate at Cosmic Rays. We ordered the chicken/rib/mashed potato meal, the chicken finger meal & an extra order of fries to all share! It was delicious!!! We all got a great meal & only paid about 8 bucks a piece! Not a bad deal.
Spectromagic Parade & Wishes:
We found a place on the curb just to the right of Partners & waited for the parade. It was still beautiful. We got a great picture of the villain from Night on Bald Mountain (Cant think of his name at the moment). After the parade, we moved to Main Street to wait for Wishes. Once again, it was beautiful! I was not thrilled with all of the Cinderellabration equipment on the stage that blocked some of the castle. That firework show can bring tears to my eyes every time I see it! After the show, Christy turned to me & Cat & said, This really has been the best day of my life!
As we were leaving, Mickey was waving telling everyone goodbye. It was a perfect ending to the perfect day at Magic Kingdom!
"What ARRRRGH you doing?"
"What are you doing?"
"No, What ARRRRGH you doing?"Cap'n Jack lives again!"I'll try anything once or twice, that's the kind of mouse I am"
Sounds great! Hope you had a magical time!
Por favor mantanganse alijado de las puertas.
Thanks Taylor! We had a blast!!
"What ARRRRGH you doing?"
"What are you doing?"
"No, What ARRRRGH you doing?"Cap'n Jack lives again!"I'll try anything once or twice, that's the kind of mouse I am"
By the way...the name of the Fantasia villain is Chernabog...he's my icon! LOL
If we can dream it, we can do it.
Thanks Kevin! I can NEVER remember his name!
"What ARRRRGH you doing?"
"What are you doing?"
"No, What ARRRRGH you doing?"Cap'n Jack lives again!"I'll try anything once or twice, that's the kind of mouse I am"


text:
Creating an account with Tribecafilm.com gives you access to more features and services, like our weekly newsletter and other special features just for the film community.
Print Source
Alex Garcia
FiGa Films
Los Angeles,
Phone: 323 309 4856
US Sales Contact
Sandro Fiorin
FiGa Films
Los Angeles,
Phone: 323 258 5241
International Sales Contact
Sandro Fiorin
FiGa Films
Los Angeles,
Phone: 323 258 5241
Press Contact
Tiffany Malloy
Tribeca Film Festival
New York,
Phone: 201 925 1122
This film is co-presented by:
When tickets for a screening or event are no longer available, they will be listed as RUSH. The Rush system functions as a stand-by line that will form at the venue approximately 45 minutes prior to scheduled start time. Admittance is based on availability and will begin 15 minutes prior to program start time. Rush Tickets are the same price as advance tickets payable upon entry. There is a limit of one Rush Ticket per person.


text:
In Reply to: Re: Wanted: Ford NAA/Jubilee Selec-trol valve posted by souNdguy on November 05, 2008 at 10:39:49:
Thanks for the super quick reply - you and I have traded emails about hydraulics in the past (one armed loader) and I appreciate your help.
I've read, re-read, and read again the excellent piece that Paul put together. My situation doesn't quite fit - unless I'm missing something. I recently bought a Jubilee. It is somewhat 'farmerised'. It does not have the stock hydraulic top plate that Paul's project is contingent on. Get this; the Jubilee I have actually has the 'other' rather rare hydraulic accessory valve that has been modified to supply hydraulic pressure to a Dearborn Dozer/Snowplow blade. The mods don't stop there. The ram for the blade is not stock. Instead of gravity down, it has down pressure, as supplied by the modified accessory valve. I've attached a picture of the type of valve that my Jubilee has. What's pictured is not actually my valve - but one that Ed Gooding has stashed on his fine website. The configuration of the valve on my Jubilee has rendered the rear lift arms inoperative. I'd like them back. And I'm not hard over on having down pressure on the Dearborn blade. I thought I could have my cake and eat it too with the Selec-Trol valve. The touch control lever would operate either the rear lift arms, or the Dearborn blade depending on the position of the Selec-Trol valve. Now, if these Selec-Trol valves are made of unobtanium (or gold), then I'll move on. What do you think?


text:
The program in advanced education in general practice residency is accredited by the Commission on Dental Accreditation. The commission is a specialized accrediting body recognized by the United States Department of Education. The Commission on Dental Accreditation can be contacted by phone at 312-440-4653 or by mail at 211 East Chicago Avenue, Chicago, IL, 60611.
The commission has accredited the postdoctoral program in general practice residency; however, this education area is not one of the American Dental Association's (ADA) recognized dental specialty areas. Therefore dentists graduating from this program cannot announce that they are specialists, as recognized by the ADA.
The GPR program participates in both the "PASS" and "Match" programs. Apply for PASS.
For more information contact the administrative assistantat 401-444-7195 or email firstname.lastname@example.com.
To read more about the program, download our brochure. (Note: the information in the brochure will change depending on the fiscal year. Please contact us for the most up-to-date information.)
| More about the Residency Program


text:
The latest version of Adobe Flash Player is required to watch this video. Please click on the link below to download the latest version. Thanks!
Well-known televangelist Creflo Dollar is the target of a new lawsuit.
California businessman Devone Lawson filed the suit against the pastor Wednesday.
Lawson claims he spent a year working with Dollar's ministry to develop a spiritual text messaging service, but was then shut out when dollar started another company with a similar service called "Word on the Go."
Attorneys for the inventor estimate the service generates more than $50 million a year.
No one at Dollar's ministry could be reached for comment.
Dollar is the founder of World Changers Church International Church in Atlanta, Ga.
Log in or create an account to post a comment.
Are you seeking answers in life? Are you hurting? Are you facing a difficult situation?
Find peace with God, discover more about God or send us your prayer request.
Call The 700 Club Prayer Center at 1 (800) 823-6053, 24 hours a day.
A caring friend will be there to pray with you in your time of need.
CBN News is a national/international, nonprofit news organization that provides programming by cable, satellite, and the Internet, 24-hours a day. Follow us on Facebook, Twitter, and Google+.
More Info
Sign up for the CBN News Dispatch and receive CBN News Reports in your inbox each day.Subscribe Now >>
Add CBN News, articles, latest videos and blog feeds to your favorite RSS reader. Subscribe Now >>
E-mail us your news tips, story ideas, questions & comments. Contact Us >>


text:
Rome Through The Ages
Rome Through The Ages is a three credit, interdisciplinary course taught in the Spring semester. Students will be able to take this course for credit in history, theology, or art, whichever one for which they sign up. This course on Roman culture will embrace several unusual features. The classroom experience will be limited to 15 classes taught on Mondays and Wednesdays from 3:30 to 5:00 PM. The remaining course requirements will be fulfilled by participation in an 8 day trip to the city of Rome during the Spring break. The focus of our excursion to Rome will be on-site visits to some of the most important and interesting historical, artistic and religious monuments of one of Europe's most important and beautiful cities.
Onsite visits in Rome include the following places and many others not mentioned: the Fora, Colosseum, Circus Maximus, Seven Hills, Pantheon, Museums(Capitoline and Vatican), Vatican City(St. Peter's Basilica, Sistine Chapel, Library, Grottoes) the Major Basilicas, churches of diverse architectural styles and those containing major artistic forms(painting, sculpture, frescoes, mosaics) created by the world's most renowned artists such as Giotto and Fra Angelico, Michelangelo and Raphael, Caravaggio and Bernini.
Included in the trip will be attendance at the Wednesday general audience with the Pope at St. Peter's
Important considerations for prospective students include the following requirements:
the course is limited to 20 students;
enrollment will be available to qualified students only from any of the four classes of HCC students, first year to fourth year students;
2 academic pre-requisites for the course include from any of the following courses:
Theo 140(Intro to Theology)
Hist 101(Western Civilization I) or Hist 102(Western Civilization II)
Hist 323 (Greek Civilization) or Hist 331(Renaissance and Reform)
Art 115(Art History Survey)
Latin I or II
In addition to the tuition fee for the class itself, the cost of the trip will be announced later once it is set by our travel agent and will include ground and air transportation to and from Rome, hotel accommodations and continental breakfasts at the hotel, and tickets to museums and public transportation in the City.
Enrollment for this class will take place in the Fall semester during the times regularly scheduled for signing up for classes. Shortly after the school year begins this August an informational meeting will take place where I will provide more specific details about the class and the trip and where potentially interested students will have an opportunity to ask pose questions they may have regarding these.
For more information regarding the class or the trip to Rome contact:
Fr. Michael Sullivan, csc
Theology/Philosophy Chair
Holy Cross College
(574) 239 8419
Rome City Tour—Tentative Itinerary
Your adventure begins when you board your overnight flight for Rome.
Arrive in Rome this morning where you will be met and transferred to your hotel, The Pomezia. This afternoon walk to the Piazza della Rotonda where you will find the Pantheon, a Roman masterpiece, one of the largest, most complete ancient buildings, which was constructed about AD 125. It has a huge concrete dome with a central oculus opened to the sky, representing a major engineering feat. This Temple of all the Gods, for nineteen centuries had the biggest dome in the world, and also the bronze doors are the largest that actually exist from the ancient Roman world. Inside the temple, you will find the tombs of the first two kings of the Italian State, and also the tomb of the painter Raphael. The piazza was Rome's fish market for centuries turning into a bird market in the 19th century. You will also visit Santa Maria sopra Minerva church with Michelangelo's statue of Jesus the Redeemer, the Piazza Navona & the Bernini Fountains as well as the Church of San Luigi dei Franchesi and the Church of St. Augustine where you will view several paintings of Caravaggio.
Join Father Michael Sullivan, CSC for Mass at a local church. This afternoon enjoy another day of sight-seeing including the Roman Forum & Colosseum and Rome's earliest hills, the Capitoline, the Palatine and the Aventine. The beginnings of Rome initiated in the area known as the Roman Forum and the Palatine Hill, essential parts of any tour in Rome, and must be visited! Within an acceptable walking distance the remains of the centers of government, entertainment and religion can be admired: the Senate House, the Temple of Vesta and the Colosseum. The Colosseum is one of the most famous monuments of ancient Rome, with an elliptical shape that measures over 530 meters in circumference and could hold over 50,000 people, who would enter it from its eighty doors. For more than three hundred years it was the place where the Romans could enjoy cruel shows such as ferocious combats between gladiators, public massacres where criminals and undesirables were fed to wild beasts, and mock naval battles.
Spend your day in Rome exploring St. Peter's Square, the Basilica, roof, dome & crypt. The opulent, gilt-encrusted St. Peter's is the most imposing church in Christendom and the ultimate destination for pilgrims and visitors interested in masterpieces of art and architecture. The dome, designed by Michelangelo, is one of the largest in the world, but when you approach it through Bernini's monumental Piazza San Pietro, the dome sees to sink behind the church's high facade, which was designed by Carlo Maderno after Michelangelo's death.
The basilica contains magnificent works of art, including Michelangelo's Pieta, the tomb of Clement XIII by Canova and a stunning mosaic by Giotto. The incredible amount of gold mosaic work and Bernini's enormous, ornate bronze baldachino are striking, as is the sheer size of the building. On the lower level is a crypt where many popes (and four women) are buried.
You'll also visit the Vatican Museum, where some of the richest collections of artifacts in the world are kept & tour the Sistine Chapel where Michelangelo's famous frescos cover the ceiling and the Last Judgment, covers the entire wall behind the altar.
St. John Lateran is your sight-seeing destination today. This is the oldest, and ranks first among the four great "patriarchal" basilicas of Rome. The site was, in ancient times, occupied by the palace of the family of the Laterani. You will also visit the Holy Stairs, the Church of San Clemente with two underground Christian churches and a pagan temple as well as the Church of St. Peter in Chains which houses Michelangelo's magnificent sculpture of Moses.
The day begins day with a visit to the Pope during a General Papal audience before exploring the Castel Sant'Angelo . The Castel Sant'Angelo was built, as was the Elian bridge in front, by the Emperor Hadrian (117-138) as a Mausoleum for himself and his successors. It was completed by Antoninus Pius in 139. In 271, the Emperor Aurelian incorporated the pile into the defense system he designed: it lost its function as a tomb to become a fortress. The Gianiculum Hill with is large park and one of Rome's best panoramic views of the city will be a good setting for lunch followed by a tour of the Trastevere region, one of the City's oldest regions across the Tiber and site of the Basilica of Santa Maria in Trastevere regarded as Rome's oldest public church.
Your explorations today will include St. Paul's Outside the Walls, the Catacombs of San Sebastiano, and the Trappist Abbey of the Tre Fontane site of St. Paul's excution by the sword. About 2 km away on the Via Ostiense rises the Basilica St. Paul outside the walls, built over the burial place of the Apostle of the Gentiles and consecrated in 324. The building of the first place of worship over St. Paul's tomb has been attributed to the Emperor Constantine.
The Catacombs were a subterranean burial place for the Christians. All catacombs were outside the walls of the city, as there was a law forbidding the burial of bodies within the precincts of Rome. The Catacombs of San Sebastiano were Rome's first catacombs and served for a period of time as the resting place of the bones both of Saints Peter and Paul.
Your wonderful trip to Rome had to end. This morning you'll transfer to the airport for your return flight to Chicago. Welcome Home.
For more information regarding the class or the trip to Rome contact:
Fr. Michael Sullivan, csc
Theology/Philosophy Chair
Holy Cross College
(574) 239 8419
Click her to download Picture Yourself... or Word Document: Trip Description or Rome Tentative Itinerary or Rome Webpage
Return to Holy Cross College


text:
Biosketch / Results /
Alan B Frey, Ph.D.
Associate Professor; Course Director-Tutorial in Cell BiologyDepartment of Cell Biology (Cell Biology)
Contact Info
550 First Avenue
Floor 6 Room 623
Medical Science Building
New York,
212-263-8129, 212-263-5354
— Dr. Frey was a Princeton University Postdoctoral Fellow in Molecular Biology, PostDoctoral Training— Sackler Institute of Biological Sciences, Medical Education
1985 — New York University, Graduate Education
Research Summary
Cancers are antigenic and recruit CD8+ T cells into the tumor tissue, referred to as ''TIL'' for tumor infiltrating lymphocytes. However, antitumor T cells are dysfunctional and are defective in cytolysis. Since exocytosis of lytic granules from T cells may potentially be dependent upon Immune Synapse (IS) formation and non-lytic tumor infiltrating lymphocytes (TIL) cannot exocytose granules, we considered that TIL IS formation or function is defective. Therefore, in conjugates formed between TIL and cognate tumor cells, using a combination of confocal microscopy and biochemical assays, we investigated the localization and activation status of proteins important in signal transduction, IS formation, and lytic function. Signal transduction in freshly-isolated, non-lytic TIL is defective: they do not flux calcium, activate PLCI?-1, increase protein tyrosine phosphorylation, or recruit WASp, Pyk-2, F-actin and the microtubule organizing center (MTOC) to the target contact site (CS) formed between TIL and cognate target cells. The block in signaling is proximal since LAT is not phosphorylated and ZAP70, although recruited to the CS, is only weakly activated. Importantly, the inhibitory motif in p56lck (Y505) becomes rapidly phosphorylated upon binding to cognate tumor cells. Consistent with a proximal signaling defect, Csk is recruited to the plasma membrane and Shp-2 is retained in the cytoplasm. In addition, Shp-1 localizes at the CS where it may mediate de-activation of various SH3-containing proteins (such as ZAP70) therein preventing propagation of the activation signal. Furthermore, we showed that upon contact with cognate target cells, non-lytic TIL assemble many signaling components (TCRI?I?, CD3I?, p56lck, ZAP70, LFA-1, LAT, and lipid rafts) with kinetics typical of activated CD8+ T cells, showing that non-lytic TIL are triggered by conjugate formation. However, CD2, the CD3 complex, and CD8, which associate with the TCR prior to conjugate formation, rapidly dissociate and are excluded from the CS. Tumor-induced disruption of T cell activation at a point downstream of triggering, therein blocking proximal tyrosine kinase activity, calcium flux, and dependent lytic function, is a novel mechanism for inhibition of the CD8+ T cell effector phase. Collectively our data suggests that proximal TCR-mediated signaling in non-lytic TIL is rapidly blocked after conjugation with cognate tumor target cells. The signaling defect likely is mediated by tumor-induced enhanced Shp-1 activity in TIL which prevents activation of proximal tyrosine kinase activity, affinity upregulation of LFA-1, and calcium flux ultimately preventing exocytosis of lytic granules and lysis of tumor cells. Importantly, the TIL lytic defect is an acquired property restricted to T cells within the tumor microenvironment since in vivo systemic T cell function is not affected by tumor growth whereas TIL are characterized by the inability to mobilize the MTOC to the CS and exocytose lytic granules. Acquired transient lytic defects in TIL have also been described in several transgenic TCR mouse tumor models. Consideration of the observation that human TIL are antigen-specific but non-lytic, together with our description of defective lytic function of murine TIL, supports the notion that tumor-induced inhibition of TIL lytic function may be a common characteristic which may contribute to tumor growth in the presence of antitumor immune response. Tumor-induced lytic dysfunction also may restrict T cell based immunotherapy of cancer. Current research investigates the detailed biochemical basis of the tumor-induced profound defect in T cell signaling.Research Interests
CD8+ T Cell immune response in cancerResearch Keywords
immune response in cancer, tumor immunology, vaccine therapy

All data from NYU Health Sciences Library Faculty Bibliography — -
A novel p56lck-interacting protein expressed in CD8+memory cells and tumor infiltrating T cells that inhibits proximal TCR-mediated signaling
Frey, Alan; Burns, Jeremy; Vazquez-Cintron, Edwin
2012 MAY 1;188:-, Journal of immunology (1950)
id: 169546,
year: 2012,
vol: 188,
page: ,
stat: Journal Article,
Dendritic Cell Populations With Different Concentrations of Lipid Regulate Tolerance and Immunity in Mouse and Human Liver
Ibrahim, J; Nguyen, AH; Rehman, A; Ochi, A; Jamal, M; Graffeo, CS; Henning, JR; Zambirinis, CP; Fallon, N; Barilla, R; Badar, S; Mitchell, A; Rao, R; Acehan, D; Frey, AB; Miller, G
2012 Jun;:1061-1072, Gastroenterology
id: 172916,
year: 2012,
vol: ,
page: 1061,
stat: Journal Article,
Myeloid-Derived Suppressor Cells and anti-tumor T cells: a complex relationship
Monu, Ngozi R; Frey, Alan B
2012 ;41(6-7):595-613, Immunological investigations
id: 179092,
year: 2012,
vol: 41,
page: 595,
stat: Journal Article,
MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells
Ochi, Atsuo; Nguyen, Andrew H; Bedrosian, Andrea S; Mushlin, Harry M; Zarbakhsh, Saman; Barilla, Rocky; Zambirinis, Constantinos P; Fallon, Nina C; Rehman, Adeel; Pylayeva-Gupta, Yuliya; Badar, Sana; Hajdu, Cristina H; Frey, Alan B; Bar-Sagi, Dafna; Miller, George
2012 Aug;209(9):1671-1687, Journal of experimental medicine
id: 177029,
year: 2012,
vol: 209,
page: 1671,
stat: Journal Article,
Protocadherin-18 is a novel differentiation marker and an inhibitory signaling receptor for CD8(+) effector memory T cells
Vazquez-Cintron, Edwin J; Monu, Ngozi R; Burns, Jeremy C; Blum, Roy; Chen, Gregory; Lopez, Peter; Ma, Jennifer; Radoja, Sasa; Frey, Alan B
2012 ;7(5):e36101-e36101 e36101, PLoS one
id: 166801,
year: 2012,
vol: 7,
page: e36101,
stat: Journal Article,
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
Weiss, Jonathan M; Bilate, Angelina M; Gobert, Michael; Ding, Yi; Curotto de Lafaille, Maria A; Parkhurst, Christopher N; Xiong, Huizhong; Dolpady, Jayashree; Frey, Alan B; Ruocco, Maria Grazia; Yang, Yi; Floess, Stefan; Huehn, Jochen; Oh, Soyoung; Li, Ming O; Niec, Rachel E; Rudensky, Alexander Y; Dustin, Michael L; Littman, Dan R; Lafaille, Juan J
2012 Sep;209(10):2291-2299, Journal of experimental medicine
id: 178843,
year: 2012,
vol: 209,
page: 2291,
stat: Journal Article,
Dendritic cells promote pancreatic viability in mice with acute pancreatitis
Bedrosian, Andrea S; Nguyen, Andrew H; Hackman, Michael; Connolly, Michael K; Malhotra, Ashim; Ibrahim, Junaid; Cieza-Rubio, Napoleon E; Henning, Justin R; Barilla, Rocky; Rehman, Adeel; Pachter, H Leon; Medina-Zea, Marco V; Cohen, Steven M; Frey, Alan B; Acehan, Devrim; Miller, George
2011 Nov;141(5):1915-26.e1, Gastroenterology
id: 139730,
year: 2011,
vol: 141,
page: 1915,
stat: Journal Article,
In hepatic fibrosis, liver sinusoidal endothelial cells acquire enhanced immunogenicity
Connolly, Michael K; Bedrosian, Andrea S; Malhotra, Ashim; Henning, Justin R; Ibrahim, Junaid; Vera, Valery; Cieza-Rubio, Napoleon E; Hassan, Burhan U; Pachter, H Leon; Cohen, Steven; Frey, Alan B; Miller, George
2010 Aug 15;185(4):2200-2208, Journal of immunology (1950)
id: 111819,
year: 2010,
vol: 185,
page: 2200,
stat: Journal Article,
Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor
Connolly, Michael K; Mallen-St Clair, Jon; Bedrosian, Andrea S; Malhotra, Ashim; Vera, Valery; Ibrahim, Junaid; Henning, Justin; Pachter, H Leon; Bar-Sagi, Dafna; Frey, Alan B; Miller, George
2010 Apr;87(4):713-725, Journal of leukocyte biology
id: 108918,
year: 2010,
vol: 87,
page: 713,
stat: Journal Article,
Tumor-induced disruption of proximal TCR-mediated signal transduction in tumor-infiltrating CD8+ lymphocytes inactivates antitumor effector phase
Vazquez-Cintron, Edwin J; Monu, Ngozi R; Frey, Alan B
2010 Dec 15;185(12):7133-7140, Journal of immunology (1950)
id: 116210,
year: 2010,
vol: 185,
page: 7133,
stat: Journal Article,
In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha
Connolly, Michael K; Bedrosian, Andrea S; Mallen-St Clair, Jon; Mitchell, Aaron P; Ibrahim, Junaid; Stroud, Andrea; Pachter, H Leon; Bar-Sagi, Dafna; Frey, Alan B; Miller, George
2009 Nov;119(11):3213-3225, Journal of clinical investigation
id: 105172,
year: 2009,
vol: 119,
page: 3213,
stat: Journal Article,
Signaling defects in anti-tumor T cells
Frey, Alan B; Monu, Ngozi
2008 Apr;222:192-205, Immunological reviews
id: 92674,
year: 2008,
vol: 222,
page: 192,
stat: Journal Article,
Skewing the Th cell phenotype toward Th1 alters the maturation of tumor-infiltrating mononuclear phagocytes
Nonaka, Kenichi; Saio, Masanao; Suwa, Tatsuhiko; Frey, Alan B; Umemura, Naoki; Imai, Hisashi; Ouyang, Guan-Feng; Osada, Shinji; Balazs, Margit; Adany, Roza; Kawaguchi, Yoshihiro; Yoshida, Kazuhiro; Takami, Tsuyoshi
2008 Sep;84(3):679-688, Journal of leukocyte biology
id: 96103,
year: 2008,
vol: 84,
page: 679,
stat: Journal Article,
Protein kinase Cdelta regulates antigen receptor-induced lytic granule polarization in mouse CD8+ CTL
Ma, Jennifer S Y; Monu, Ngozi; Shen, David T; Mecklenbrauker, Ingrid; Radoja, Nadezda; Haydar, Tarik F; Leitges, Michael; Frey, Alan B; Vukmanovic, Stanislav; Radoja, Sasa
2007 Jun 15;178(12):7814-7821, Journal of immunology (1950)
id: 96104,
year: 2007,
vol: 178,
page: 7814,
stat: Journal Article,
Suppression of proximal T cell receptor signaling and lytic function in CD8+ tumor-infiltrating T cells
Monu, Ngozi; Frey, Alan B
2007 Dec 1;67(23):11447-11454, Cancer research
id: 75676,
year: 2007,
vol: 67,
page: 11447,
stat: Journal Article,
TNF expressed by tumor-associated macrophages, but not microglia, can eliminate glioma
Nakagawa, Jiro; Saio, Masanao; Tamakawa, Noriyuki; Suwa, Tatsuhiko; Frey, Alan B; Nonaka, Kenichi; Umemura, Naoki; Imai, Hisashi; Ouyang, Guan-Feng; Ohe, Naoyuki; Yano, Hirohito; Yoshimura, Sinichi; Iwama, Toru; Takami, Tsuyoshi
2007 Apr;30(4):803-811, International journal of oncology
id: 96105,
year: 2007,
vol: 30,
page: 803,
stat: Journal Article,
Myeloid suppressor cells regulate the adaptive immune response to cancer
Frey, Alan B
2006 Oct;116(10):2587-2590, Journal of clinical investigation
id: 69693,
year: 2006,
vol: 116,
page: 2587,
stat: Journal Article,
Effector-phase tolerance: another mechanism of how cancer escapes antitumor immune response
Frey, Alan B; Monu, Ngozi
2006 Apr;79(4):652-662, Journal of leukocyte biology
id: 66694,
year: 2006,
vol: 79,
page: 652,
stat: Journal Article,
Defective adhesion in tumor infiltrating CD8+ T cells
Koneru, Mythili; Monu, Ngozi; Schaer, David; Barletta, Justine; Frey, Alan B
2006 May 15;176(10):6103-6111, Journal of immunology (1950)
id: 64588,
year: 2006,
vol: 176,
page: 6103,
stat: Journal Article,
T-cell receptor signaling events triggering granule exocytosis
Radoja, Sasa; Frey, Alan B; Vukmanovic, Stanislav
2006 ;26(3):265-290, Critical reviews in immunology
id: 67541,
year: 2006,
vol: 26,
page: 265,
stat: Journal Article,
Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function
Koneru, Mythili; Schaer, David; Monu, Ngozi; Ayala, Aidee; Frey, Alan B
2005 Feb 15;174(4):1830-1840, Journal of immunology (1950)
id: 50292,
year: 2005,
vol: 174,
page: 1830,
stat: Journal Article,
Immunocytochemical demonstration of down regulation of HLA class-I molecule expression in human metastatic breast carcinoma
Saio, Masanao; Teicher, Matt; Campbell, Gaynor; Feiner, Helen; Delgado, Yara; Frey, Alan B
2004 ;21(3):243-249, Clinical & experimental metastasis
id: 67542,
year: 2004,
vol: 21,
page: 243,
stat: Journal Article,
Expression of rat complement control protein Crry on tumor cells inhibits rat natural killer cell-mediated cytotoxicity
Caragine, Theresa A; Imai, Masaki; Frey, Alan B; Tomlinson, Stephen
2002 Nov 1;100(9):3304-3310, Blood
id: 93833,
year: 2002,
vol: 100,
page: 3304,
stat: Journal Article,
A tumor-expressed inhibitor of the early but not late complement lytic pathway enhances tumor growth in a rat model of human breast cancer
Caragine, Theresa A; Okada, Noriko; Frey, Alan B; Tomlinson, Stephen
2002 Feb 15;62(4):1110-1115, Cancer research
id: 91293,
year: 2002,
vol: 62,
page: 1110,
stat: Journal Article,
The role of fibroblasts in thymocyte-positive selection
Lilic, Mirjana; Santori, Fabio R; Neilson, Eric G; Frey, Alan B; Vukmanovic, Stanislav
2002 Nov 1;169(9):4945-4950, Journal of immunology (1950)
id: 34693,
year: 2002,
vol: 169,
page: 4945,
stat: Journal Article,
CD8(+) tumor-infiltrating lymphocytes are primed for Fas-mediated activation-induced cell death but are not apoptotic in situ
Radoja S; Saio M; Frey AB
2001 May 15;166(10):6074-6083, Journal of immunology (1950)
id: 20291,
year: 2001,
vol: 166,
page: 6074,
stat: Journal Article,
CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis
Radoja S; Saio M; Schaer D; Koneru M; Vukmanovic S; Frey AB
2001 Nov 1;167(9):5042-5051, Journal of immunology (1950)
id: 25552,
year: 2001,
vol: 167,
page: 5042,
stat: Journal Article,
Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide
Saio M; Radoja S; Marino M; Frey AB
2001 Nov 15;167(10):5583-5593, Journal of immunology (1950)
id: 25551,
year: 2001,
vol: 167,
page: 5583,
stat: Journal Article,
Protection against tick-transmitted Lyme disease in dogs vaccinated with a multiantigenic vaccine
Straubinger, RK; Rao, TD; Davidson, E; Summers, BA; Jacobson, RH; Frey, AB
2001 Oct 12;20(1-2):181-193, Vaccine
id: 28209,
year: 2001,
vol: 20,
page: 181,
stat: Journal Article,
Type I IFN modulates innate and specific antiviral immunity
Durbin JE; Fernandez-Sesma A; Lee CK; Rao TD; Frey AB; Moran TM; Vukmanovic S; Garcia-Sastre A; Levy DE
2000 Apr 15;164(8):4220-4228, Journal of immunology (1950)
id: 11766,
year: 2000,
vol: 164,
page: 4220,
stat: Journal Article,
Distinct requirements for IFNs and STAT1 in NK cell function
Lee CK; Rao DT; Gertner R; Gimeno R; Frey AB; Levy DE
2000 Oct 1;165(7):3571-3577, Journal of immunology (1950)
id: 20292,
year: 2000,
vol: 165,
page: 3571,
stat: Journal Article,
Cancer-induced defective cytotoxic T lymphocyte effector function: another mechanism how antigenic tumors escape immune-mediated killing [In Process Citation]
Radoja S; Frey AB
2000 Jun;6(6):465-479, Molecular medicine
id: 11514,
year: 2000,
vol: 6,
page: 465,
stat: Journal Article,
Mice bearing late-stage tumors have normal functional systemic T cell responses in vitro and in vivo
Radoja S; Rao TD; Hillman D; Frey AB
2000 Mar 1;164(5):2619-2628, Journal of immunology (1950)
id: 8539,
year: 2000,
vol: 164,
page: 2619,
stat: Journal Article,
Where have all the T cells gone? Mechanisms of immune evasion by tumors
Finke, J; Ferrone, S; Frey, A; Mufson, A; Ochoa, A
1999 Apr;20(4):158-160, Immunology today
id: 636212,
year: 1999,
vol: 20,
page: 158,
stat: Journal Article,
NKT cell cytokine imbalance in murine diabetes mellitus
Frey AB; Rao TD
1999 ;29(3):201-214, Autoimmunity
id: 6171,
year: 1999,
vol: 29,
page: 201,
stat: Journal Article,
Protection from Lyme neuroborreliosis in nonhuman primates with a multiantigenic vaccine
Pachner AR; Delaney E; Zhang WF; O'Neill T; Major E; Frey AB; Davidson E
1999 Jun;91(3):310-313, Clinical immunology
id: 8508,
year: 1999,
vol: 91,
page: 310,
stat: Journal Article,
Multidose streptozotocin induction of diabetes in BALB/cBy mice induces a T cell proliferation defect in thymocytes which is reversible by interleukin-4
Wood SC; Rao TD; Frey AB
1999 Feb 25;192(1):1-12, Cellular immunology
id: 6056,
year: 1999,
vol: 192,
page: 1,
stat: Journal Article,
Protection of human breast cancer cells from complement-mediated lysis by expression of heterologous CD59
Yu J; Caragine T; Chen S; Morgan BP; Frey AB; Tomlinson S
1999 Jan;115(1):13-18, Clinical & experimental immunology
id: 7468,
year: 1999,
vol: 115,
page: 13,
stat: Journal Article,
Oncogenes and immunity: immune responses against products of transforming genes and the effects of oncogene activity on immunogenicity
Appleman L; Frey AB
Molecular approaches to tumor immunotherapy Singapore : World Scientific, 1998,
id: 3588,
year: 1998,
vol: ,
page: ?,
stat: Chapter,
Rat NKR-P1+ CD3+ T cells: selective proliferation in interleukin-2, diverse T-cell-receptor-Vbeta repertoire and polarized interferon-gamma expression
Badovinac V; Boggiano C; Trajkovic V; Frey AB; Vujanovic NL; Gold DP; Mostarica-Stojkovic M; Vukmanovic S
1998 Sep;95(1):117-125, Immunology
id: 7999,
year: 1998,
vol: 95,
page: 117,
stat: Journal Article,
Repression of interleukin-2 mRNA translation in primary human breast carcinoma tumor-infiltrating lymphocytes
Lopez CB; Rao TD; Feiner H; Shapiro R; Marks JR; Frey AB
1998 Dec 15;190(2):141-155, Cellular immunology
id: 7394,
year: 1998,
vol: 190,
page: 141,
stat: Journal Article,
Administration of silica sensitizes lipopolysaccharide responsiveness of murine macrophages but inhibits T and B cell priming by inhibition of antigen presenting function
Rao TD; Frey AB
1998 May;27(3):181-199, Immunological investigations
id: 7751,
year: 1998,
vol: 27,
page: 181,
stat: Journal Article,
Soluble proteins isolated from Borrelia burgdorferi by extraction with Triton X-114 confer resistance to experimental infection
Rao TD; Frey AB
1998 Oct;89(1):94-104, Clinical immunology & immunopathology
id: 7431,
year: 1998,
vol: 89,
page: 94,
stat: Journal Article,
Study of immune response to tumors in the rat
Frey AB
1997 Jun;12(2):173-188, Methods
id: 7149,
year: 1997,
vol: 12,
page: 173,
stat: Journal Article,
Killing of rat adenocarcinoma 13762 in situ by adoptive transfer of CD4+ anti-tumor T cells requires tumor expression of cell surface MHC class II molecules
Frey AB; Cestari S
1997 May 25;178(1):79-90, Cellular immunology
id: 7150,
year: 1997,
vol: 178,
page: 79,
stat: Journal Article,
Tumors antigens encoded by oncogenes and the impact of oncogenes upon the immune responses
Appleman LJ; Frey AB
1996 May 25;170(1):1-10, Cellular immunology
id: 8048,
year: 1996,
vol: 170,
page: 1,
stat: Journal Article,
Role of host antigen receptor-bearing and antigen receptor-negative cells in immune response to rat adenocarcinoma 13762
Frey AB
1996 May 15;156(10):3841-3849, Journal of immunology (1950)
id: 6995,
year: 1996,
vol: 156,
page: 3841,
stat: Journal Article,
Dominant-negative p53 can restore tumorigenicity of L-929 cells in immunocompetent mice
Appleman LJ; Frey AB
1995 Nov 15;63(4):576-583, International journal of cancer
id: 7930,
year: 1995,
vol: 63,
page: 576,
stat: Journal Article,
Mouse embryo fibroblasts transformed by activated ras or dominant-negative p53 express cross-reactive tumor rejection antigens
Appleman LJ; Uyeki J; Frey AB
1995 Jun 9;61(6):887-894, International journal of cancer
id: 12762,
year: 1995,
vol: 61,
page: 887,
stat: Journal Article,
Rat mammary adenocarcinoma 13762 expressing IFN-gamma elicits antitumor CD4+ MHC class II-restricted T cells that are cytolytic in vitro and tumoricidal in vivo
Frey AB
1995 May 1;154(9):4613-4622, Journal of immunology (1950)
id: 12776,
year: 1995,
vol: 154,
page: 4613,
stat: Journal Article,
Expression of activated H-rasval12 in nontumorigenic and non-cross-reactive syngeneic cells induces tumor antigens cross-reactive with rat mammary adenocarcinoma 13762
Frey AB; Cestari S
1995 Nov 15;155(10):4783-4789, Journal of immunology (1950)
id: 6825,
year: 1995,
vol: 155,
page: 4783,
stat: Journal Article,
Single exposure of mice to Borrelia burgdorferi elicits immunoglobulin G antibodies characteristic of secondary immune response without production of interleukin-4 by immune T cells
Frey AB; Rao TD
1995 Jul;63(7):2596-2603, Infection & immunity
id: 6623,
year: 1995,
vol: 63,
page: 2596,
stat: Journal Article,
Apparent split tolerance of CD8+ T cells from beta 2-microglobulin-deficient (beta 2m-/-) mice to syngeneic beta 2m+/+ cells
Jhaver KG; Rao TD; Frey AB; Vukmanovic S
1995 Jun 15;154(12):6252-6261, Journal of immunology (1950)
id: 7900,
year: 1995,
vol: 154,
page: 6252,
stat: Journal Article,
Protective resistance to experimental Borrelia burgdorferi infection of mice by adoptive transfer of a CD4+ T cell clone
Rao TD; Frey AB
1995 May;162(2):225-234, Cellular immunology
id: 12773,
year: 1995,
vol: 162,
page: 225,
stat: Journal Article,
Th1 T cell immune response is produced in mice either by infection or immunization with Borrelia burgdorferi
Rao, T. D.; Frey, A. B.
1995 ;5(1):27-39, Immunology & infectious diseases
id: 98792,
year: 1995,
vol: 5,
page: 27,
stat: Journal Article,
Rat adenocarcinoma 13762 expresses tumor rejection antigens but tumor-bearing animals exhibit tumor-specific immunosuppression
Frey AB; Appleman LJ
1993 Nov;69(2):223-233, Clinical immunology & immunopathology
id: 13053,
year: 1993,
vol: 69,
page: 223,
stat: Journal Article,
Regulated replication of an episomal simian virus 40 origin plasmid in COS7 cells
Chittenden T; Frey A; Levine AJ
1991 Nov;65(11):5944-5951, Journal of virology
id: 55867,
year: 1991,
vol: 65,
page: 5944,
stat: Journal Article,
Differential expression of MAG isoforms during development
Pedraza L; Frey AB; Hempstead BL; Colman DR; Salzer JL
1991 Jun;29(2):141-148, Journal of neuroscience research
id: 14013,
year: 1991,
vol: 29,
page: 141,
stat: Journal Article,
Protein zero of peripheral nerve myelin: biosynthesis, membrane insertion, and evidence for homotypic interaction
D'Urso, D; Brophy, P J; Staugaitis, S M; Gillespie, C S; Frey, A B; Stempak, J G; Colman, D R
1990 Mar;4(3):449-460, Neuron
id: 606392,
year: 1990,
vol: 4,
page: 449,
stat: Journal Article,
Epstein-Barr virus DNA replication
Frey A; Chittenden T; Levine AJ
1989 ;144:227-232, Current topics in microbiology & immunology
id: 55869,
year: 1989,
vol: 144,
page: 227,
stat: Journal Article,
p53-plus-ras-transformed rat embryo fibroblasts express tumor-specific transplantation antigen activity which is shared by independently transformed cells
Frey AB; Levine AJ
1989 Dec;63(12):5440-5444, Journal of virology
id: 55868,
year: 1989,
vol: 63,
page: 5440,
stat: Journal Article,
Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP
Clarke CF; Cheng K; Frey AB; Stein R; Hinds PW; Levine AJ
1988 Mar;8(3):1206-1215, Molecular & cellular biology
id: 55870,
year: 1988,
vol: 8,
page: 1206,
stat: Journal Article,
Determination of the membrane topology of the phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4 using site-specific antibodies
De Lemos-Chiarandini C; Frey AB; Sabatini DD; Kreibich G
1987 Feb;104(2):209-219, Journal of cell biology
id: 18421,
year: 1987,
vol: 104,
page: 209,
stat: Journal Article,
Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines
Hinds PW; Finlay CA; Frey AB; Levine AJ
1987 Aug;7(8):2863-2869, Molecular & cellular biology
id: 55871,
year: 1987,
vol: 7,
page: 2863,
stat: Journal Article,
3-(Trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine photolabels a substrate-binding site of rat hepatic cytochrome P-450 form PB-4
Frey AB; Kreibich G; Wadhera AB; Clarke L; Waxman DJ
1986 Aug 26;25(17):4797-4803, Biochemistry
id: 18423,
year: 1986,
vol: 25,
page: 4797,
stat: Journal Article,
The structure of phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4. Production and characterization of site-specific antibodies
Frey AB; Waxman DJ; Kreibich G
1985 Dec 5;260(28):15253-15265, Journal of biological chemistry
id: 18424,
year: 1985,
vol: 260,
page: 15253,
stat: Journal Article,
Induction of cytochrome P-450 isozymes in rat hepatoma-derived cell cultures
Frey AB; Rosenfeld MG; Dolan WJ; Adesnik M; Kreibich G
1984 Aug;120(2):169-180, Journal of cellular physiology
id: 18429,
year: 1984,
vol: 120,
page: 169,
stat: Journal Article,
Studies on the subunit composition of rat liver glutathione S-transferases
Frey AB; Friedberg T; Oesch F; Kreibich G
1983 Sep 25;258(18):11321-11325, Journal of biological chemistry
id: 18430,
year: 1983,
vol: 258,
page: 11321,
stat: Journal Article,
Synthesis and incorporation of myelin polypeptides into CNS myelin
Colman DR; Kreibich G; Frey AB; Sabatini DD
1982 Nov;95(2 Pt 1):598-608, Journal of cell biology
id: 18436,
year: 1982,
vol: 95,
page: 598,
stat: Journal Article,
Studies on the biosynthesis of microsomal membrane proteins. Site of synthesis and mode of insertion of cytochrome b5, cytochrome b5 reductase, cytochrome P-450 reductase and epoxide hydrolase
Okada Y; Frey AB; Guenthner TM; Oesch F; Sabatini DD; Kreibich G
1982 Feb;122(2):393-402, European journal of biochemistry
id: 18440,
year: 1982,
vol: 122,
page: 393,
stat: Journal Article,
Colman, DR; Kreibich, G; Frey, AB; Sabatini, DD
1981 ;91(2):A404-A404, Journal of cell biology
id: 30541,
year: 1981,
vol: 91,
page: A404,
stat: Journal Article,
Location of a gelatin-binding region of human plasma fibronectin
Furie MB; Frey AB; Rifkin DB
1980 May 25;255(10):4391-4394, Journal of biological chemistry
id: 42396,
year: 1980,
vol: 255,
page: 4391,
stat: Journal Article,


text:
All of you who guessed that a Hansen miniSpinner is my new wheel are right!
Here's what UPS brought on a day so snowy my husband and I had help dig out the truck when it got stuck at the end of our road.
Yes, two boxes, I got many things, just a second and I'll show you.
The boxes were so well packed, not one thing shifted.
Here's everything unpacked:
I got a maple eSpinner and it's beautiful. I got a WooLee Winder, the regular Hansen flyer, extra bobbins, the quill, orifice reducers and the brand new Lace flyer. I'm a little overwhelmed. I've been spinning a little and it's dreamy. I forgot about the fumbled fingered way I spin when I get a new wheel. I try to spin about six different types of yarn simultaneously. I'll be doing a big review in the First Fall issue of Knitty and until then I'll be getting to know her.
My next decision is which Züca bag to get:
Those of you that have Hansen eSpinners, I would love to hear any tips you have!


text:
George Visger in His Own Words: A Career of Concussions
Football damaged my brain and it didn't have to happen
GEORGE VISGER, a former 49er, tells his story
Due to the size and speed of today's football players, the kinetic energy they generate during hits can have long-term consequences. Here's my story:
My football career began at age 11 in 1970 when I suited up for the West Stockton Bear Cubs, the first Pee Wee Pop Warner team fielded in Stockton, Calif. Of the 29 kids on the team, three went on to sign NFL contracts in 1980 (myself — sixth round, New York Jets; Jack Cosgrove — eighth round, Seattle Seahawks; Pat Bowe — free agent, Green Bay Packers).
During my third year of Pop Warner, I was hospitalized when I knocked myself unconscious during a tackling drill. The exercise was a needless bull-in-the-ring drill that was more of a gladiator competition for the coaches' amusement than a means of teaching useful techniques to young players.
The coaches had us form a big circle about 25 yards across and numbered the 40 of us 1 to 20 on each side. When your number was called, you and the player on the other side with the same number sprinted directly at each other and hit head-to-head.
Concussions followed throughout my high school career, though I never missed a game or practice. In my senior year, we went 11-0 and ranked No. 3 in California. I was selected to the All-America Top 100 Team.
I entered the University of Colorado on a football scholarship in 1976 as a 6-foot, 5-inch 235-pound defensive tackle, majoring in biology. I was a starter for three years and suffered a number of minor concussions, but I never missed a play except after leg injuries.
Turning pro
In 1980, I was drafted into the NFL by the New York Jets at 259 pounds. The Jets had me beef up to 275 pounds. I was cut at the end of preseason but was picked up by the San Francisco 49ers early in the regular season.
On my first play with the 49ers in the first quarter against Dallas, I suffered a major concussion but played the entire game. The trainers told me afterward I went through 25 to 30 smelling salts on the sidelines. They would give me a handful each time I came out, I'd pop a couple, clear the cobwebs and go back in. We laughed about it as I watched the game films the next day and didn't remember a single play. Still, I never missed a practice.
Early in my second season with the 49ers, a few weeks after my first knee surgery, I developed hydrocephalus (water on the brain) and underwent emergency surgery to put a shunt in my brain that would drain trapped spinal fluid. I turned 23 lying in intensive care at Stanford Hospital.
Four months after we won Super Bowl XVI my shunt failed while on a fishing trip to Mexico with my brother Mel. He brought me back to the states in a coma. I had back-to-back emergency brain surgeries 10 hours apart and was given last rites the next day. I also was given the hospital bills and ended up suing the 49ers for workers compensation.
Life after football
For nearly five years I fought off creditors for the massive hospital bills while undergoing two more knee surgeries, including an experimental GoreTex ACL transplant. The workers comp case was settled in 1986, so at least my medical bills finally were covered.
That year I also returned to school at Sacramento State University to complete my biology degree. In 1987, while taking a full course load, I survived four more brain surgeries and several gran mal seizures, including a 55-minute seizure while sitting in organic chemistry class.
In 1990 I graduated at age 32 with a degree in biological conservation and have since been working as a wildlife biologist and environmental consultant.
Now 52, I suffer major short-term memory problems and have survived nine football-related emergency brain surgeries and multiple gran mal seizures. To combat seizures I take Lamictil, the sixth anti-seizure medicine I have taken due to horrible side effects from previous ones.
Struggling to cope
Over the years I have assembled an arsenal of coping mechanisms.
For 20-some years, I've written everything I do in Rite-in-the-Rain notebooks — small waterproof notebooks I began using for field notes when I first became a biologist — because I can't remember much of anything from day to day. I always carry one in my back pocket and write several pages a day, including the time and content of each phone call.
Every few days I review the prior week or so of notes to recall what I've done. I tell everyone I work with to never fear hurting my feelings if they have to remind me of an appointment. My home, truck and office are littered with Post-It notes. I set beeping reminders on my computer and phone, and still struggle to stay on top of commitments.
I also take fish-oil supplements, drink concentrated fruit and seaweed juices and take daily one-and-a-half hour treatments inside a pressurized chamber of pure oxygen to reduce inflammation in my brain and improve my memory.
Dr. Richard G. Ellenbogen, co-chair of the NFL Head, Neck and Spine Medical Committee, contacted me last spring and asked me to share my suggestions as to how players' heads could be better protected.
Several of my recommendations are being implemented thanks to Dr. Ellenbogen and his fellow co-chair, Dr. H. Hunt Batjer, including the controversial new standards on helmet-to-helmet hits (although I would make the penalties much tougher). They truly are trying to change the culture of football to protect players, especially younger players who emulate what they see on TV.
I recently coordinated a meeting with Dr. Ellenbogen and Steve Reimers of the Hyperbaric Oxygen Medical Association in an attempt to get hyperbaric chambers installed in all NFL locker rooms.
Concussions kill
In October, Nathan Stiles, a 17-year-old high school football star and homecoming king in Kansas, died of post-concussion syndrome after intercepting a pass and slamming his head on the turf during a typical tackle. He'd suffered a concussion earlier in the month during the homecoming game.
My heart goes out to his family and friends.
It's time we realize the human brain was not meant to be used as a weapon or repeatedly banged into the ground.
One of my suggestions that probably will never happen: Get rid of helmets. All the new technology makes one feel that much more invincible to injury.
I know I did.


text:
does anyone have an easy burrito recipe to share? I love these and buy so many??? |
Follow-Up Postings:
- Posted by Bugs(firstname.lastname@example.com) onWed, Aug 29, 01 at 13:36
I make them different ways but basically either use the following: cooked ground beef, shredded chicken or refried beans or half meat and half beans I have also mashed up a tin of baked beans to substitue and it worked good. If just using meat season with some chili powder, salt, pepper and a spoon of bouillon is great too. Use big tortilla shells and add about a 1/2 cup of the meat/bean mixture on the middle half of the shell, then layer a fistful of lettuce, tomato, onion, cheddar cheese. You can cook the onion with the meat too if you like. Fold over filling, sides in then roll over. Heat in the oven for about 15 min on 350, you can also microwave them, freeze them or use a little oil on the outside and make them a little crsipy while cooking. |
- Posted by Michelle_MO (My Page) on Wed, Aug 29, 01 at 13:44
I like this one (makes about 8-12 depending on the size of tortilla you use and how full you stuff 'em!) 1 lb ground beef, ground turkey, or cubed chicken optional Brown beef and use taco seasoning as directed on package. Mix refried beans in a small bowl with about 1 Tbsp of salsa (helps to make the beans a little easier to spread) and heat in microwave approx. 1 min 30 sec - just enough to make them easy to stir and spread. Heat tortillas one at a time on hot griddle (or use oven or microwave directions on tortilla package if you prefer). Spread each tortilla with beans, top with seasoned meat, cheese, sour cream, onions and salsa. Fold in 2 sides about 1" and roll up. Freeze on baking sheet until firm, then store in ziploc freezer bags. |
- Posted by Don(email@example.com) onWed, Aug 29, 01 at 16:05
Hi, I brown one pound of ground beef, add a jar of store bought salsa, one can of frioles, and melt in a sliced up pound of jack cheese. Makes about a dozen large burritos. Haven't had a complaint yet. |
Stop...you're making me hungry!! I have a questions though with the frozen burritos. Do you thaw them out first before you re-heat them or do you just put them in the microwave? Also, how long do you cook them after they have been frozen? Sorry for all the questions, but these sound like they'd make great lunch ideas to take to work. Sue |
- Posted by Bugs(email@example.com) onThu, Aug 30, 01 at 8:34
I usually take mine to work frozen then by lunch it is partially thawed if not fully then only have to heat it for about 2 minutes in the micro. |
Thanks, Bugs. I'll be making some of these this weekend! Sue |
I love bean burritos and I like them highly seasoned I have used cannned beans but really like them better when using home cooked dried beans. I saute onion and garlic and then add the beans and mash........when they are nice and smooth I add lots of cumin and grated cheese........soooooooo good. |
- Posted by Dustbunni(firstname.lastname@example.com) onThu, Sep 13, 01 at 12:49
Gosh, you can make burros out of just about anything you like. Here's a family favorite. Egg and potato burros. 4 mediup potatoes cut into small cubes. 1/2 onion chopped Minced garlic to taste Saute the above in oil until potatoes are lightly browned and cooked through. Crack 4-6 eggs over the top and scramble them in. Spoon this filling into flour tortilla. Add a strip of cheddar cheese. Add a pinch of chopped cooked bacon, ham, or sausage if desired. Roll up your buritto. Brown lightly in oil. Cool. Freeze. I've kept these for up to two months,(but only because they got lost in the freezer).I usually use within a month. Thaw in your lunch bag or microwave. Heat and serve. |
- Posted by Vicki_from_Nevada (My Page) on Thu, Oct 4, 01 at 17:32
I remember there used to be a burrito sold at our county fairs in California that had if I remember correctly, hamburger and green chili peppers (probably Ortega chili's). Anyone have an idea what this recipe might be. It was delicious. |
- Posted by Nicole(email@example.com) onThu, Oct 11, 01 at 9:18
I shred leftover chicken, mix with whatever leftover veggies I have, a drained can of diced tomatoes and Ortega burrito seasoning, and cook them on the George Foreman grill. I gives it a crunchy outside (kinda like a chimichanga, except it's not fried). The grill is also really good for breakfast burritos. Nicole |
Please Note: Only registered members are able to post messages to this forum. If you are a member, please log in. If you aren't yet a member, join now!
Return to the Once-a-Week Cooking Forum
Information about Posting
- You must be logged in to post a message. Once you are logged in, a posting window will appear at the bottom of the messages. If you are not a member, please register for an account.
- Please review our Rules of Play before posting.
- Posting is a two-step process. Once you have composed your message, you will be taken to the preview page. You will then have a chance to review your post, make changes and upload photos.
- After posting your message, you may need to refresh the forum page in order to see it.
- Before posting copyrighted material, please read about Copyright and Fair Use.
- We have a strict no-advertising policy!
- If you would like to practice posting or uploading photos, please visit our Test forum.
- If you need assistance, please Contact Us and we will be happy to help.
Learn more about in-text links on this page here


text:
Overall Rank:
Avg. Rating:
# of Ratings:
Theater Date:
DVD Release:
Ewan McGregorNaomi WattsGeraldine ChaplinMarta EturaTom HollandOaklee Pendergast
Like Movie:
Plot Outline:
Based on the 2004 tsunami that hit Thailand, a family is caught up in the chaos of the aftermath with tens of thousands of other people as their sons go missing following the devastating natural disaster. -- Chris Kavan
Characters left. Want more? See how.
Matthew Brady 08/01/2014 (0 of 0 found this helpful)
Rating of 3/4
Nothing is more powerful than the human spirit. Okay this movie is a true story well they are some things in this movie that was not really true like the wave itself I mean it looks more bigger then the photos.
Allison 06/12/2014 (0 of 0 found this helpful)
Great performance by Naomi Watts!
Alex 08/11/2013 (0 of 1 found this helpful)
Rating of 2.5/4
Surprisingly pretty good. I understand that it is based on a true story but much of it seems far fetched. The beginning starts off really well but once the family is clearly separated it looses steam. Throw in a few dumb parts with the kids and you have an above average film that falls a little flat. Still a decent feel good drama but not for me.
02/06/2013 (0 of 0 found this helpful)
Great feel good movie
I want to start this review by saying that if you are in a time in your life where you think everything is bad have a look at this film as it will make you feel that things aren't really that bad. Definatly the feel good movie of 2012. When i originally heard via Cnn in 2004 that on Boxing day of all days, that a 30ft Tsunami had hit the asian islands i could not believe my eyes as to the catastrophe that ensumed the eastern peninsula also the death toll was nothing short of astronomical with the huge wave leaving 230,000- 280,000 dead in it's wake. The worst mother nature disaster in history. The Impossible is based on the true life story of Maria Belon, a spanish physician (Although she was portrayed by english actress Naomi Watts who is nominared for best actress for it) who...
Rating of4/4
01/29/2013 (0 of 0 found this helpful)
The Impossible review
"It's a beautiful mystery isn't it?" Intense, moving and powerful. On Christmas Eve the Bennett family spend their vacation In Thailand. A tsunami hits and Maria Bennett (Naomi Watts) and her husband Henry (Ewan McGregor) and their three sons Lucas (Tom Holland), Tomas and Simon get lost in the incident. It has the most horrific/authentic opening disaster sequence on-screen. The hospital was grueling as well. This critic has never grimaced and winced as much on a movie, and this is a drama. Naomi Watts has that ability, to pull you in because of her vulnerability/pain because of the power to convince. McGregor was heart-wrenching as well. It's baffling how the Academy Awards snubbed a picture of this magnitude. Best lines: Maria - "You get to go and do something. Go help people....
01/20/2013 (0 of 0 found this helpful)
The Impossible (2013) Based on a true story of a family who, while on vacation at a coastal resort in Thailand, are separated after a devastating Tsunami hits. Naomi Watts, in an Academy Award nominated role, plays Maria, the mom who has given up being a doctor to raise her family. Ewan McGregor plays the father, Henry, who, when separated from his wife and oldest boy, risks his own life to find them once again. Watts is brilliant in the role of a woman who is determined to make sure that her oldest son (Tom Holland) survives the ordeal, even if it means risking her own life. The special effects are incredibly realistic and you get the full effect of what it would be like to be hit by a tidal wave of water and debris. This is an awe-inspiring film that keeps you not only on the edge of...
Advertise and Business
Developer API
Contact Us
About us
Support FilmCrave
FAQ and Help
News and Press
Terms of Use


text:
Bryn Mawr College recently changed the Environmental Studies program from a concentration into a minor!
The Environmental Studies minor embodies Bryn Mawr's commitment to educating students to be agents for sustainable change in the world. Students in the program are able to master a variety of applications of sustainability, from geology and ecology to urban planning and environmental justice.
In the senior seminar for ES minors, students work to create applicable projects, many of which have benefited the Bryn Mawr community. Some of these include a syllabus for an Environmental Literacy PE course, a plan for a workable garden, and a bi-college transportation study.
Please see the Environmental Studies website for more information: Environmental Studies


text:
Rookie of the Year, five All-Star appearances, a National League MVP award, and glass urine containers. These are all items currently ingrained in the legacy of Ryan Braun. As Major League Baseball continues to funnel time, money, and energy into the Biogenesis clinic and the players who allegedly hold ties to the PED house, at least one of the names implicated in the scandal is leaving a lasting impact on the landscape of scary sports drugs. According to a report from Andy Martino at the New York Daily News, MLB has made a switch from plastic urine containers to glass in light of Ryan Braun's successful challenge on a 50-game PED suspension.
Braun overturned his suspension by challenging the sample collection process. The Milwaukee Brewers star's urine sample remained in possession of the collector for two days before it was sent to the lab for to be tested. Prior to Braun's victory, MLB used triple-sealed plastic containers to collect and transport urine samples. Now, as Martino reports, glass containers are used:
Now, the collectors use glass bottles, made by the same manufacturer, but considered even more secure. The bottles have a locking mechanism on the top, as opposed to tamper-proof stickers on the plastic version. The only way to open the glass bottles is to smash the top with a hammer, which the lab does in what a person familiar with the process described as a "controlled manner."
Martino notes the new glass containers will be more difficult to tamper with. While there was no announcement on the change, it was part of several changes made to the league's testing program over the last year.


text:
Bon Appétit | November 2005
I found myself with LOTS of extra stuffing and decided to try this. It was good, easy, and different. I used Pecorino Romano for the cheese because that is what I had. One thing, though. Use less salt! I used 1/2 t., and it was quite sufficient!!
28 reasons why doughnuts (and doughnut holes)baked or fried, glazed or dustedare perfect morning, noon, and night
plus: everything you need to know about making doughnuts at home ›
Get the inside dish on 10 restaurants Parisians don't want you to know about
plus: Over 1,300 recipes à la Française to cook at home ›


text:
Narrow Results By
- Holiday & Gifts > Gift Shop > Gourmet Gift Baskets
Beach Table Top Decor
Relax Table Top Decor
Surf's Up Table Top Decor
- Home Decor > Decorative Accessories > Decorative Accents
Shop school merchandise, find local stores and schedule pickup or delivery for your stuff!
Pick out what you want, and invite family and friends to pick up the tab.
Help is always available at 1-800-GO-BEYOND®
(1-800-462-3966). Please view our Returns Policy if you aren't satisfied with your order.
© 2015 Bed Bath & Beyond Inc. and its subsidiaries | Build : 2.05.01.006 | Build From : null | Tag Id : 2.05.01.006


text:
Valhalla Sales & Marketing Co., Visalia, is traditionally among the latest to offer navels, said Steve Nelsen, co-owner.
"We don't have any early, early varieties," he said. "We'll probably begin shipping about Dec. 1."
The volume of organic navels from Sunkist Growers also should be up this season. One reason for the increase is new acreage that has transitioned from conventional to organic, Smith said.
Harvest of organic navels will not likely begin before mid-December, she said, and sizes will be similar to conventional navels, slightly smaller than the 2009-10 crop.
Grower-shippers are winding down their valencia seasons. Most will have the fruit through October and some into early November, they said.
California's traditional summer orange crop is becoming a smaller and smaller player in the citrus game.
"It's a great tasting piece of fruit," said Mike Wootton, senior vice president for corporate relations and administration for Sunkist Growers. "The problem for the valencia has been the fact that there's so much competing product, not just citrus, but everything else that's in the marketplace today as well as all the Southern Hemisphere production."
Wileman Bros. & Elliott will have valencias at least until the start of its navel harvest, Felts said.
Fans of minneolas will have to wait until late in the year to find California-grown fruit on market shelves.
Valhalla Sales & Marketing could have limited supplies of minneolas the last week in December, Nelsen said. Sunkist Growers is scheduled to begin harvesting the desert crop of minneolas the week of Dec. 13, Smith said. The desert crop's volume is down as much as 30%, she said.
The variety grown in other regions of California will reach maturity after the first of the year, grower-shippers said, with volume about the same as last season.
Wileman Bros. & Elliott expects its minneola harvest to begin in February, Felts said. January is the target start for Sunkist's nondesert minneola crops, Smith said.
The harvest is expected to continue at least through February.


text:
Balloons are a festive way to create an elegant and fun party atmosphere.
Our creative design team with over a decade of experience is always available for corporate theme and color suggestions. We can incorporate your company logo and colors in any design. Whatever your occasion we'll create a stunning and memorable effect. We offer numerous balloon decorating ideas from simple balloon centerpieces to exploding cloudbusters, all designed to enhance your special event.
The very best parties deserve the very best balloons! Our staff only uses qualatex balloons! Use them for...
Large or small, we have the expertise to create the desired atmosphere to make your event spectacular, and do it all at a price that fits within your budget! Call today and speak to a staff creative designer regarding your upcoming event and you will have ideas, colors and themes emailed to you within 48 hours for your convenience.
Design by Stadia Studio


text:
The JetScan iFX is the latest technology and the fastest, most accurate cash counter and check scanner available. The JetScan iFX i100 processes 1,600 bills per minute – 33% faster than other money counting equipment. With fewer jams and advanced counterfeit detection, it's the fastest, most accurate cash counter machine around.
Designed for simple software upgrades, you can add serial number capture, check scanning and other document processing features as your needs change.
Contact us today to learn more about how the JetScan iFX i100 currency scanner can improve your business immediately!
Mixed bill processing: Count cash and denominate 33% faster than comparable currency counting models - up to 1,600 mixed bills per minute - to end shifts on time.
Serial number capture: Capture full-size images of every bill at up to 1,200 bills per minute for a highly effective means of tracking currency.
Counterfeit detection: The most advanced counterfeit detection in the industry, patented sensors and analytic software analyze each bill, catching counterfeits that others miss.
Check scanning: Process checks at 400 documents per minute. Reduce overtime costs, extend deadlines, and improve employee morale.
Future-ready design: Easily upgrade select models with a software activation key as new features become available.
As seen on the Steve Harvey Show.
Contact us today for prices on this product as well as pricing for other products and solutions that fit your needs.
Deposit balancing manager: Deposit preparation and processing completed in minutes. Process high-volume transactions faster and more accurately. Send electronic deposits to financial institutions via ICL.
Serial number capture: Capture and record serial numbers at 1,200 notes per minute.
Check imaging: Capture dual-sided check images at 400 documents per minute.
Check archive solution: Digitally capture check images and eliminate the need to store or microfiche physical documents.
Counterfeit detection: Choose from a wide range of counterfeit detection sensors,including magnetic ink, fluorescence, ultraviolet, infrared and IQ™ Sensing Technology.
Printers: Impact or thermal printers provide records of transactions.
Optional currencies: Canadian dollar (CAD), Euro (EUR), Turkish lira (TRY), Mexican peso (MXN), and Argentine peso (ARS).
Feeder | |
Type | Automatic feeder with auto-sensing document detection. |
Transport | |
Type | High-volume straight-through transport path. |
Exit Pocket Capacity | |
Maximum Capacity | 200 documents. |
Physical Specs | |
Dimensions | 9.5" H (without hopper) x 13.5" W x 13" D |
Weight | 20 lbs. |
Document Size |
Height: 2.41" to 4.0" Length: 4.5" to 8.75" |
Currency Processing Specs | |
Adjustable Processing Speed | 600, 800, 1,000, 1,200 and 1,600* notes per minute. (*Serial number capture is not available at 1,600 notes per minute) |
Denominations Scanned | $1, $2, $5, $10, $20, $50 and $100 |
Accuracy | 99.99+% |
Feeder Capacity |
Brick Currency: 500 notes Circulated Currency: 400 notes |
Imaging Specs | |
Document/Media Type | Checks (personal and business), currency and deposit slips. |
Image Capture Speed | 400 documents per minute (based on personal size checks). |
Feeder Capacity |
Personal Checks: 500 documents Mixed Checks: 200 documents (Personal and/or Business Checks) |
Output Resolution | 200 x 200 dpi |
Image/Data Transmission Format | TIFF |
Scanning Method | Front and rear image capture in one pass. |
Detection | Auto size, automatic document type, MICR character no read, piggyback, double, and chain. |
Image Quality | Background removal and cropping. |
Image Enhancement Technology | Digitally remove wrinkles from the image and align skewed documents. |
External Bar Code Scanner | Optional for label entry via USB port. |
External Keyboard | Optional keyboard/keypad via USB port. |
Printer | Optional Citizen impact or thermal printers available. |
Communications | USB, RS232, and Ethernet |
Suspect Note Detection | Options include imaging, magnetic ink, fluorescence, ultraviolet and IQ® sensors. |
Touch Panel Display | 4.3", full-color, touch-screen display with on-screen diagnostics. |
Operating System | |
Platform | Windows CE |
Cummins Allison is committed to keeping your equipment up and running so your organization performs at its best.
That's just one reason why our technicians are noted for their expertise, quick response and friendly customer service. Rigorous training is regularly conducted to ensure that our technicians are able to keep your equipment operating at peak efficiency.
Over 400 highly-trained local service technicians
50+ Cummins Allison-owned branch offices with local parts inventories
National Field Service provides advanced technical support for our branch operations
Worldwide Service Organization provides advanced technical support for our subsidiaries and distributors around the world
Cummins Allison products are designed to provide maximum productivity with minimal care requirements.
However, all machines need regular upkeep and maintenance. The Cummins Allison Preventative Maintenance Inspection Agreement (PMIA) reduces operating costs by extending the productive life and increasing the reliability of these products.
Your covered equipment is inspected and serviced on your premises on a scheduled basis. This includes partial disassembly; vacuuming, wiping and cleaning; plus lubrication and adjustments to factory specifications. Parts are replaced when needed to prevent possible breakdowns. Your machines are thoroughly tested to assure optimum working order.
Scheduled inspections find and fix little problems before they become big, unscheduled problems.
Your equipment always operates at peak efficiency.
The useful service life of your machines is extended for better return on investment.
Maintenance costs are easy to budget. The PMIA cost can be scheduled into your operating budget -- with no big surprise expenses.
Emergency service for problems that may occur between scheduled maintenance visits is free (during normal business hours).
PMIAs include all parts, labor, emergency service, preventative maintenance inspections, upgrades to existing software and all upgrades for new or redesigned currencies released by the US government during the term of the maintenance agreement.


text:
Address: | Moscow, Russia |
Contact: | http://www.last.fm/music/Mujuice |
Similar in Moscow: | Tesla Boy People, Narkotiki People |
Similar Worldwide: | siohem Band (Samara), mplasek Band (Samara), Apparat Band (Berlin) |
He is a student of graphic design and also works professionally in this field.
He began his musical experience in early childhood by composing small piano pieces. Working without a formal musical education, he integrated his experience as a member of a hardcore guitar band with his first electronic music experiments while in his teens.
Source: http://www.last.fm/music/Mujuice


text:
Open Access
Wiley is committed to developing products and services which meet the needs of the scholarly community and support author choice. In partnership with our society and journal partners, we offer the following open access options to complement our subscription publishing:
Pay to publish open access publishing | Self-archiving open access | |
Wiley Open Access a program of fully open access journals. | OnlineOpen a hybrid open access option for over 1300 journals | Self Archiving for peer-reviewed (but not final) versions on a personal website or company/ institutional repository |
Resources for Librarians
Information and ideas to help promote Wiley online content to library users.
Customer Administration
Pricing and Licensing
Resources for Authors
Information on publishing with Wiley.
Author Services
Open Access
English Language Editing
Copyright Matters
More Resources
Resources for Societies
Wiley helps professional and scholarly societies succeed in today's changing information landscape with two centuries of publishing expertise.
Resources for Media
Find breaking news from Wiley Publishing and search an archive of press releases in the Wiley Press Room.


text:
trends bear a strong resemblance to the Northern Hemisphere's leading pattern of variability, the Arctic Oscillation/North Atlantic Oscillation (AO/ NAO) (Thompson and Wallace, 1998; Wallace, 2000). That is, the observed trends in the wintertime temperatures and precipitation appear to be largely regional expressions of the positive trend of the AO/NAO. There are indications of analogous trends in the Southern Hemisphere, in association with its annular mode (Thompson et al., 2000).
Several ideas have been put forth concerning the cause of those trends. Shindell et al. (1999, 2001) have proposed that they might be occurring in response to increasing concentrations of greenhouse gases, which warm the lower atmosphere but cool the stratosphere. Indeed, similar trends have been simulated in an atmospheric model driven by increasing concentrations of greenhouse gases. It has also been suggested that stratospheric ozone depletion (Volodin and Galin, 1999) and trends in sea-surface temperatures (Rodwell et al., 1999; Hoerling et al., 2001) might be capable of inducing similar trends in the AO/NAO. Because favored patterns of variability tend to be highly sensitive to external forcing, it is indeed quite plausible that they can be changed in a number of ways. Fyfe et al. (1999) give a contrasting view, that the AO/NAO did not appear to be altered substantially by greenhouse forcing, yet its Southern Hemisphere counterpart, the annular "AAO" mode, was indeed strongly amplified.
Whatever its cause, the observed trend in the AO/NAO is influencing other components of the earth system. The trend has altered the distribution of deep convection over the North Atlantic (Lilly et al., 1999, Dickson et al., 1996), caused glaciers in Norway to advance (Hurrell, 1995), and contributed to the thinning of the stratospheric ozone layer over middle and high latitudes of the Northern Hemisphere during winter and early spring (Thompson et al., 2000). Interactions with the oceanic thermohaline circulation (THC) have the potential to exert positive feedback on the AO/NAO itself, increasing its variability on decadal and longer scales. Owing to such feedback, it is conceivable that shifts in the AO/NAO contributed to some of the large climatic swings in the paleoclimate record.
If trends observed in the AO/NAO during the last 30 years were to continue into the twenty-first century, they could have important societal impacts. For example, the recovery of the stratospheric ozone layer from human-induced depletion during the twentieth century could be delayed by several decades (Shindell et al., 1999).


text:
Immizen View
A tribute to US multiculturalism
Stories & Poetry
Electoral College List
About Us
A brief geographical history of the "United" States …
Top Rated
Recent Posts
No Cheese
Complacency and the November Elections 2014
Big Bang: You Had Me At Singularity
The Fox News's Propaganda Machine Grasping at Straws
Obamacare. Aplica Hoy!
Father/Daughter Conversation about Obamacare
Meet The Fox News Welfare Surfer
The Art of Tango Dancing
NBC: Wealth of 85 richest people equal to wealth of half of the world's population
Koch Brothers' Obsession with Punishing the Poor
Teacher Pay 1940-2013: Losing Ground, Losing Status
Sarah Palin: sheFunny :(
Obamacare Awareness & Halloween Pimps
The news of the day in one picture
When it comes to poisoning people, right and left agree: US should focus on Monsanto not Syria
Don't be black in Florida. Don't be a woman in Texas. Don't be poor in America.
Breaking my silence on the Trayvon Martin case
Almost Dorothy returns with Edward Snowden
NSA poll shows partisan shift: If my Prez does it, it's okay!
Who says Republicans Hate Welfare?
If your prejudices made people sick…
IRS Scandal will backfire for Tea Party and Republicans
Business is booming in Texas
The 45 senators who chose to forget
Gun Votes For Sale
Is it a "good thing" or is it "a right"?
Jim Carrey: Fux News is a a media colostomy bag that has begun to burst at the seams
Harlem Shake in Egypt – A Little Protest Dance For Democracy
What Nerd Jargon Teaches Us About Obama, Ducks and How to Pass Laws
A Reason To Live (Oscars Short Film Edition)
Young Republicans Becoming the Forecasters of Doom
Obama's reelection bringing Fox News down – SOTU Fox News rating down 47%
Praise the Lord and Pass the Ammunition
FB wall post: "Obama will hurt military families"
In Mississippi, bible laws forcing the last remaining abortion clinic to close down
Why Republicans hate Chuck Hagel
Guns, Money & the 2nd Amendment
MASS: Mothers Against School Shootings
The World is Watching
Tax the Rich, An Animated Fairy Tale
Copyright © 2015
Immizen View
- All Rights Reserved
Powered by


text:
Recent Comments:
WRUP: Infuriating launcher detected {WoW}
Aug 7th 2010 3:26PM I haven't heard of this problem before. My download client stops at 100% at 4.1GB to go, but it doesn't seem to affect anything... I've been leveling my mage in new Tirisfal Glades quite well.
It's strange to think that I can play it and other people, who seem to have the exact same situation regarding the Updater, can't. Does the Play button not work for them?
Cataclysm Beta: New blacksmithing items revealed {WoW}
Jul 1st 2010 7:51AM I guess it's all in how you look at it. I just enjoy upgrading my characters' gear. Even with the "gear reset", I found it more enjoyable to play on my relatively newly 80 warrior than my raid-geared main, simply because my warrior was faced with much more clear-cut upgrades than my main.
The Queue: Strictly business. {WoW}
Jan 8th 2010 9:14PM While playing today, it struck me that some of the loading screen tips were new to me. In particular, one that read, "For additional features and functionality, merge your World of Warcraft account with a Blizzard Battle.net account."
Since I'm not aware of any new features my Battle.net account gives me in WoW itself, should I take this as a hint to the launch of Battle.net 2.0?
The Queue: Blood and glory {WoW}
Nov 10th 2009 3:57PM With the new LFG system on the PTR, might a player in the random dungeon queue get paired with a player queued for a specific dungeon?
For instance, if I happen to be the only player in my entire battle group who actually wants to do Occulus, will the system force some poor saps in the random dungeon queue to join me?
The Queue: Snape, snape {WoW}
Jul 21st 2009 6:44PM In general, World of Warcraft is more centered on teamwork than individual power. While most classes and specs are in some way or another viable in a group, a large number wouldn't have a chance 1v1, which isn't fun.
Also, in a 1v1 bracket, even the slightest imbalance between specs and classes would be magnified to an absurd amount. It wouldn't be a true duel of player skill, but just a Spec of the Month contest.
Windows Home Server Power Pack 3 beta adds Windows 7 conveniences {Engadget}
Jul 17th 2009 2:04PM Will be interesting to see how this turns out, but I'm confused by the "support for full image backup of Windows 7 PCs" part... doesn't WHS already do that?
Daily Chores achievement is no longer a chore {WoW}
May 1st 2009 3:45PM I'm really glad to hear this... the prospect of not getting the title (And so my drake) because I can't play on a certain day of the week was quite disheartening.
Noblegarden will apply to What a Long, Strange Trip {WoW}
Mar 9th 2009 4:09PM That's disappointing... I hope there aren't any RNG achievements, though I suspect there are (Haven't checked yet).
Patch 3.1 Dual Spec walkthrough gallery {WoW}
Feb 24th 2009 7:14PM Any word on players being able to "configure their talents before they are saved"?
Bioshock Tuesday: win an Xbox 360 and a copy of Bioshock {Engadget}
Aug 22nd 2007 9:19AM Rainbow Six: Vegas for 360


text:
, 2 full bath. Three (3)bedroom (Maybe 4) Fieldstone Ranch home with a full basement, on 10+ acres. Good bones and More info |
. More info |
. More info |
. Build your home in this magnificent Lexington equestrian community. Flexibility to make lot larger More info |
. Rare Fine! The Island. Last custom home site on the second island backing to water. Build your cust More info |
. Build your house on the widest lot in Walnut Grove Estates - 130' wide! 200' of Green Space on side More info |
, 3 full bath, 1 half bath. Share the beautiful views of your own private pond with the abundant wildlife on this 21 acre estat More info |
. Location Location!! Beautiful 20 acre farm only 12 minutes from New Circle Rd. - 14 minutes to Winc More info |
4 bed, 3 full bath. Spectacular views from every room of this upgraded and renovated contemporary ranch. This home boas More info |
. Large lot 1. 69+ acres on Fayette County! The lot has mature trees, utilities at front with sewer a More info |


text:
We have ourselves a new Tom Buchanan, folks. It has just been announced that Aussie actor, Joel Edgerton, will be replacing Ben Affleck in Baz Luhrmann's 3D version of "The Great Gatsby." Affleck, who dropped out because of scheduling conflicts, is just the kind of A-Lister we would expect to see amongst the all-star cast, which includes Leonardo DiCaprio, Tobey Maguire, and Carey Mulligan. So who is this guy tackling the role of Tom, Daisy's millionaire, white supremacist husband? After the jump, five things you should know about Joel Edgerton, a guy you're going to be seeing a whole lot of on the silver screen. Keep reading »
Zergnet: Simply Irresistible
- Popular


text:
With the Fiesta, Ford is hoping to lure buyers into $21,000 subcompacts with high-end features like keyless ignition, satellite radio, and heated, leather seats. The Mazda 2 takes a decidedly different tack, minimizing the options and the luxuries in favor of a bargain price tag. Make no mistake, though. This isn't a stripper. Instead, Mazda includes the bare essentials that make for a well-equipped, but not opulent, vehicle. Choose the $16,185 Touring model with the manual transmission, you get an auxiliary audio input, power windows and locks, and cruise control. You even get some frivolities like foglights, steering-wheel audio controls, and red piping on the seats. However, you can't get Bluetooth, which is increasingly required equipment as states adopt handsfree phone laws. As a whole, it works out to be a great car for the buyer who wants the warranty and reliability of a new car but is strapped for cash. Frankly, the 2's pricing and packaging makes me think of the Hyundai and Kia value buys from three years ago.
The 2 also drives quite nicely. Yes, it's underpowered, but just like my first car -- a 2003 Protege5 -- this Mazda rewards the driver for maintaining momentum through corners. As Joe mentioned, there's room to stiffen the suspension, but I suspect the typical buyer will be more impressed by how comfortable such a small, affordable car is.
Eric Tingwall, Associate Editor