text:
Howdy, Stranger!
It looks like you're new here. If you want to get involved, click one of these buttons!
FJ Cruiser Manual or Auto?
We are ready to buy an FJ and can't decide whether to get a manual or auto transmission. Any thoughts on pros and cons of either (other than gas mileage)?
aperson Posts: 5I prefer driving an automatic and my husband prefers a manual. My husband is going to be the primary driver, so I guess we will go with the manual. He was just trying to figure out if there was any downside to getting the manual other than the gas mileage isn't as good. When he drove an FJ last year, there weren't any manuals available at the lot so he has only driven an automatic FJ.
tidester Posts: 10,109I think that in the end it comes down to personal preference but here are some factors you might consider:
(a) Automatic will be less tiring if you do a lot of stop and go city driving.
(b) Automatic transmissions typically cost $600 to $1,000+ more than manual transmissions.
(c) You do get better gas mileage with a manual transmission.
(d) Automatic transmissions are much more complicated than manual transmissions so reliability may be a factor, i.e. more can go wrong with them.
(e) Many feel that a manual transmission provides better "road feedback" giving them better control over the vehicle.
Did I adequately muddy the waters for you?
tidester, host
SUVs and Smart Shopper -
brownznh Posts: 2The manual does NOT get better gas mileage- check the stickers! I have a manual and I love to drive it, but the gas is killing me. It is at least 5 mpg less than auto because it is FULL TIME 4x4. On the other hand, unless you are off road, you never have to shift for bad weather/road conditions.
kawagumby Posts: 2Although a manual transmission is simpler, it comes with a part that often needs attention - the clutch. How long a clutch will last, without the need to be replaced or otherwise serviced, often depends a lot upon the driver. But for most long-term car use, a clutch will need to be replaced at least once during ownership. With today's labor charges, that can be a fairly expensive item. If the flywheel needs to be resurfaced the cost can skyrocket.
meeh Posts: 1Hello I am thinking about purchasing an FJ and was wondering whether to go with the FJ Manual or Auto. I have never driven anything but manual on my cars and trucks. Im driving a 4x4 5spd 4Runner right now. I have test driven an auto FJ and it was nice. good acceleration and handling, but there isnt an MT available to test drive. I was wondering how you guys liked it so far? How does the clutch feel? The Gears? How about the MPG? you guys getting the 15/18?Just any information on the MT FJ and the way you feel about them would be nice. Thanks.
sparklemahn Posts: 11
takafoomi1 Posts: 8Guys i have a question. A local dealership, Toyota dealer, has a yellow 6-speed 2007 FJ Cruiser with 90k miles. Apparently someone used it for commuting. Apparently I can get it for about $15,500 w/o tax and tags. The question is, should I? It's a ton of mileage in a short period of time. They tell me they've gone over it with a fine tooth comb, new tires, fluids, and so forth. It's physically clean.
I have owned/own other toyotas - my 91 MR2 Turbo has 112k miles and it's much older. Whats the risk in getting something so used up in the prime of its life? Does anyone else have a high mileage FJ?
Thanks! -
tidester Posts: 10,109That sounds like a decent price considering the miles. You may want to browse through Toyota FJ Cruiser Prices Paid and Buying Experience to get an idea of what others have been paying recently. I'll just note that the original owner was apparently concerned enough about the high miles on a two year old vehicle to trade it in.
tidester, host
SUVs and Smart Shopper
This discussion has been closed.


text:
The file you were looking for has gone totally AWOL. Shit, shit, shit! I know I put it somewhere... where the hell is it?
>>> Hey Rhona, you know that file I was using as a frisbee earlier, can you remember where I put it?
>>> Don't be such a dork! You put it in the trash compactor!
Look I am really sorry, it's gone and I don't think I can put it back together again!
Please go back to Gobananas Home page to find some relevant content of your search.

subset: commoncrawl


text:
Ricardo Appreciation SocietyRe: Ricardo Appreciation SocietyLooks familiar to the bike I am working on. I see what you mean about the front forks being replacements.
Check out my practical cycling and cycle touring website: VELOPHILE AUSTRALIA
Re: Ricardo Appreciation Societyall this Ricardo love makes me miss the first bike i ever bought, when i was a kid I saved all my hard earn't brown one dollar notes until i had $176 of them and bought what i thought was a real, fair dinkum, racing bike, with an amazing array of 10 gears , cant remember the model and it was all white, not exactly what i would have chosen as a colour when i was a kid but that was all i could have in a large size to fit me. I'd ride that thing as fast as it would take me (and before that i thought my super elliott was fast, huh! ), got pulled over by the cops on more than one occasion, a few times when as kids we would race the cars down the narrow winding steep decent into the SA country town of Yankalilla, the cops said it was dangerous, we kept doing it, duh..another time in the city (adelaide) they pulled me over at a radar trap and told me to slow down, "the speed limit applies to you too kid"
As kids we used to talk about what brands of bikes were the best, in our micro world we all thought and bragged that Ricardo was the best you could get well we all knew Porshe were the best bikes in Oz, they had a really cool emblem too, but that bloody german company that made the 4 wheel jalopies made them change their name to Ricardo!arrg! so that now made Ricardo the best bikes!!! incidentally, there are a couple of Porshe (old Ricardo) bikes on the ol auction site at the moment, with the shield emblem and South Australian Piper (magpie bird) on the head-tube, not racers unfortunately, one ladies and one roadster type thing, its got a stick shift!
Re: Ricardo Appreciation SocietyHi All
Well Finally got around to getting to the old's place and rummage through my stuff, and well I got more than I bargain for, and hopefully a bit of a treat for you all down memory lane. Not only did I have sales brochures from 1985 thru to 1988 I also had brochures for 1989 and 1990 -1991 plus I dug out my group set of early frame stickers. Plus a dealer shop sticker, for now I have uploaded for your perusal the 1985-1986/1987-1988 brochure covers and specification pages. I will further upload the later brochures once I have shrunk them down enough to fit on my scanner bed and let you know. I would like to scan these in as an Ebook if possible, so if anyone has any tips on how do so would be happy to do it. http://i758.photobucket.com/albums/xx22 ... 1289394608 http://i758.photobucket.com/albums/xx22 ... 5-1986.jpg http://i758.photobucket.com/albums/xx22 ... 7-1988.jpg http://i758.photobucket.com/albums/xx22 ... 7-1988.jpg http://i758.photobucket.com/albums/xx22 ... ickers.jpg Regards Ricardoman My Ride Ricardo "WHITE LIGHTNING" 1990 Full Shimano Tange 2 Frame, Complete Shimano 600 Ultegra componentry.
Previous Rides: Ricardo Elite 1986, Ricardo Viva 1986(Z Series), Ricardo Viva 1988.
Re: Ricardo Appreciation Society
Sweet merciful crap!!! That is fantastic RicardoMan. I think quite a number of us would dearly love to see the full sheet/brochure scans. I wouldn''t even worry about doing them as a single continuous PDF file; if you could save each page as individual JPG file or similar, one of us would gladly compile them in sequence into a PDF. It basically depends on the hardware resources (and time) you have at your disposal as well as what you can email or upload, data volume wise. I myself now have 3 Ricardo frames of reasonable to better quality construction; two 'Tange 900' Vivas and a 'Tange 2' Nuovo. Happy to help hold the torch for what I believe to be one of the last Australian made brand names. - Kym
Please don't assume I'm on Facebook.
Re: Ricardo Appreciation Society+1
Great stuff!!! fantastic to look through, i am only sad you dont have stuff from the early 70's, grass is always greener.... amazing!
Re: Ricardo Appreciation SocietyHi Drubie,
Thanks for the info and putting the pics up on the big screen. Not much on the forums application as yet. My bike has 105 throughout apart from the crank. Ricardomans info is great but is mine a White Lightning? Chainstay stickie identical to Richardomans so can only guess that the other stickies are what was on the bike originally. Funny paintwork is growing on me but to reco whole bike will require it's demise as some little rusty bits in several spots. Tonyj
Re: Ricardo Appreciation SocietyHi Tonyj
Here is the link to the Frame stickers: http://photobucket.com/White-Lightning Let me know if you need any more pics. Also after reviewing your new purchase, here is a link also to the Elite SX, Ricardo were obviously painting bikes in that style: http://i758.photobucket.com/albums/xx22 ... SX1990.jpg Do you have a serial number for this bike ?, I have been given a bit of an explanation how they are interrupted, where I purchased my bikes from the owner of the bike shop who has now retired and has been a close family friend for many years as qiven me a run down on the serial numbers. I'd be interested in comparing your serial number to mine. Ricardoman My Ride Ricardo "WHITE LIGHTNING" 1990 Full Shimano Tange 2 Frame, Complete Shimano 600 Ultegra componentry.
Previous Rides: Ricardo Elite 1986, Ricardo Viva 1986(Z Series), Ricardo Viva 1988.
Re: Ricardo Appreciation SocietyHi All
Just posted up a counter flyer from 1988-1989 for perusal. http://i758.photobucket.com/albums/xx22 ... r1988a.jpg http://i758.photobucket.com/albums/xx22 ... r1988b.jpg Enjoy Ricardoman My Ride Ricardo "WHITE LIGHTNING" 1990 Full Shimano Tange 2 Frame, Complete Shimano 600 Ultegra componentry.
Previous Rides: Ricardo Elite 1986, Ricardo Viva 1986(Z Series), Ricardo Viva 1988.
Re: Ricardo Appreciation SocietyThanks again Ricardoman..
It seems the guy who posted them originally has gone to ground, but the two near twin "Pinnacle" models here (coupla pages back in this thread) are very interesting. Only mention I've seen of any of the Ricardos with Reynolds tubing. By the L9.... serials - would that suggest they're more the period of your later model "White Lightenings"? Well chuffed with the scan you've done of that counter flyer from 1988 - that's basically my Nouvo on the front page ('cept mines a 63cm version) Please, keep the memorabililia coming. - Kym
Please don't assume I'm on Facebook.
Re: Ricardo Appreciation Society
Hi HappyHumber Glad you liked the Nouvo flyer that was it's last year of production 1988, I raced with a guy that had a Nouvo in 1986. I'll have a go at the serial number sequence and open it up for discussion, and base this of what I have interpreted and explained to me. My serial number for the White Lightning is L 90 B 0878 [L] Leisure Cycles (company name) [90] or [9] Year of manufacture [B] ? this is either model type i.e "White Lightning" or frame type i.e Tange 2 frame. [0878] ? production serial number, number made of a particular model i.e (White Lighting was introduced to production in 1989 as Ricardo's top of range road bike) So this production number may represent that count or total ongoing frame production for year 1990. As for the Pinnacle numbering it was offered in 1990 and replaced the white ligtning as there new range leader delegating the white lighting into the next model down. It's production number L9P0077 and L9P0080 were probably early production numbers for the model. There are obvious minor inconsistances in the production numbering, mine being L 90 and the Pinnacle L9, my Elite from 1986 is just stamped L 0391. I can still remember when I ordered my White Lightning and having to wait some time for it to be made, I think about a month or so at the time. On my next trip home I will grab my original receipts and actually see when I bought all my bikes. I will also check my production numbers of my Viva's off the paper work. I also had a thought that part of the serial number may have been the frame size as 87mm is also the height of my fork tube, (Probably a coincidence), however I noticed in the brochure they appear to measure by the seat tube. My final thought is there may have been some method in there serial numbers as they may have attempted to incorporate some practicality in them i.e frame type, model, production number, production year. Anyway stay tuned for more brochure picture uploads... Regards Ricardoman. My Ride Ricardo "WHITE LIGHTNING" 1990 Full Shimano Tange 2 Frame, Complete Shimano 600 Ultegra componentry.
Previous Rides: Ricardo Elite 1986, Ricardo Viva 1986(Z Series), Ricardo Viva 1988.
Re: Ricardo Appreciation SocietyJust recently recommissioned my 63cm Viva (#L7K0569) , generously passed along to me by Zeus here in the forums as a Fixed Gear general runabout & commuter. Loving it.
I found it a little odd their top of the line Nouvo was only specced with the 105 Groupset. My bike is fairly original with its 105, but otherwise pretty flogged out. I have similar period Shimano 600 components, and I plan to gradually build it back up as a 9sp friction shifter. Paint is by and large OK, with a few rust-blurred chips here and there but It should clean up well enough as is. Possibly one for the Shed sub-forum, but I wonder how some NOS Shimano Biopace rings would go with a 9speed cassette... - Kym
Please don't assume I'm on Facebook.
Customized Ricardo Society...This much used Ricardo stopped in at the LBS at the same time as me.
Note the custom head angle and fork rake. Eric. Newer does not automatically mean betterer.
Re: Customized Ricardo Society...
Is it actually jiggered, or is it merely the skewiff mudguard mountings? they might be for 700c wheels, when this is a 27" wheeled beastie.... But I tell you what - the seat post set up is definitely an eyebrow raiser! - Kym
Please don't assume I'm on Facebook.
Ritardo Society...
Yes the frame is most definitely bent - paint is flaked off top and down tubes and the forks are bent back from a collision no doubt. The bloke riding it had no clue about bikes... "I bet the handling's a bit twitchy with the forks like that ?" "Ummm, dunno." "It'd be pretty hard to ride no hands too eh ?." "Ummm, I've never ridden it no hands" Confirms my theories about Ritardo riders. Eric. Newer does not automatically mean betterer.
Re: Ricardo Appreciation Society
Always wonder about people who lurk about in topics they've only got negative things to say about. - Kym
Please don't assume I'm on Facebook.
Not All Ricardo's Are Good...The lower end Ricardo's like the one above are nothing special - K-Mart bike in their day.
Eric. Newer does not automatically mean betterer.
Re: Ricardo Appreciation Society
My nouvos were supplied with 600. YMMV
Fine. 10sp chain is starting to risk getting chain betwixt rings but nine seems to be fine. Again, YMMV Stop handing them the stick! - Dave Moulton
Re: Ricardo Appreciation SocietyHi All
More brochure Covers and data sheets to look at from 1989 and 1990. Will start the big scan work shortly on the entire brochures time permitting. Well enjoy the sneak peek. Caution when opening contains 80's styling.. http://i758.photobucket.com/albums/xx22 ... re1989.jpg http://i758.photobucket.com/albums/xx22 ... ec1989.jpg http://i758.photobucket.com/albums/xx22 ... re1990.jpg http://i758.photobucket.com/albums/xx22 ... ec1990.jpg You will note the 1990 range was quite extensive in comparison to the previous years, mainly due to the introduction of imported bikes to the lower range. All others frames were made in Australia by Ricardo. It's nice to see they were open in regards to identifying their imported models. Ricardoman. My Ride Ricardo "WHITE LIGHTNING" 1990 Full Shimano Tange 2 Frame, Complete Shimano 600 Ultegra componentry.
Previous Rides: Ricardo Elite 1986, Ricardo Viva 1986(Z Series), Ricardo Viva 1988.
Re: Ricardo Appreciation SocietyMy first 'real' bike was a Ricardo MX, black on black, loved it to death. It got pimped with black Skyway Tuffs, Shimano DX pedals and GT bar pads. Ah the memories!
Merida Ride Lite 93 2012
Mojo Urban fixed 1984 Christoff R.I.P
Re: Ricardo Appreciation SocietyI have an 1984 Ricardo Elite that I paid approx. $700 (?) for with my hard earned from uni summer vacation work. My parents were distraught at the thought of spending that much money - but it was my sole form of transport.
I want to make some room in the garage and want to 'give' it away to a good home, but to someone who appreciates the history of it. The frame and gears etc are in pretty good nick as it has never been left outside...... if anyone is interested and live in the Adelaide area happy to hear from them.
Re: Ricardo Appreciation Society
Hi Peter, if the offer is still there I'll take it. Owned a Ricardo Elite myself until I broke it and quite like the marque. I'll PM you
Re: Ricardo Appreciation Societyand here it is. Thanks to the kindness of Peter, this red one will go faster...
Ricardo Elite, Tange 900 CrMo tubeset (incl fork legs) 23inch frame, so 58 x 58cm centre-to-centre Serial # LGX 2690 All original fitout with possible exception of saddle, nearly all SR (Sakae Ringo) componentry except brakes and levers are DiaCompe and derailleurs/shifters are Shimano. Original 27inch wheels with 6 speed screw on cluster. Kept under cover all its life, usual chips and scratches in paint, only real damage is a minor dent in centre of top tube and middle braze on cable guide has been knocked off. If anyone want to know more about the build/spec let me know. Oh, and the 27in wheels will be for sale for a pittance, I'll be putting some 700c on it. SR hubs, 36 x 3 cross 14g spokes to Weinmann 27 x 1 1/4 rims. Quite tidy wheels, strong and true.
Re: Ricardo Appreciation SocietyWhat an excellent example, very nice Elite.
Ricardoman My Ride Ricardo "WHITE LIGHTNING" 1990 Full Shimano Tange 2 Frame, Complete Shimano 600 Ultegra componentry.
Previous Rides: Ricardo Elite 1986, Ricardo Viva 1986(Z Series), Ricardo Viva 1988.
Re: Ricardo Appreciation SocietyAny more juicy scans for us Ricardoman??
I'd love some of those 1988 era decals to show up.... My Nouvo paint is borderline passable at the moment. I love the yellow fade.. but my examples had it's fair share of chips & scratches. - Kym
Please don't assume I'm on Facebook.
Re: Ricardo Appreciation SocietyGot this from the dump the other day $15, just needed two new tyres and a couple of brake cables and a jolly good scrub. Man I'm loving this bike , you forget how relaxing riding can be and how going slow never felt so damn cool! Its got a Shimano 3s hub that I inadvertently disassembled whilst greasing the axle and after 2 days of scanning the net for answers I fluked it and am happy to say it works a treat. Big question is it's a Ricardo... what?? Nothing on the frame I can make out, and any ideas of the year. Look forward to hearing back.
Cheers BurtO
Who is onlineUsers browsing this forum: WestcoastPete |
Popular Bike Shops
> FREE BNA Stickers |


text:
Chrysler Voyager 2000-2003 MPV Tailgate / Boot Gas Strut.
- Price: £27.30 - In stock
- Brand: NitroLift
We recommend always replacing struts as a pair to keep the force even between them - often replacing just one strut causes the older strut to fail soon after. This is because even if an old strut hasn't totally failed it will have lost pressure, and matching it with a new strut will cause unequal forces between the two struts, side loading and premature failure of both struts.
No reviews have been found
Chrysler Voyager 2000-2003 MPV Tailgate / Boot Gas Strut.
All our products come with a minimum of a 2 year domestic warranty, with extended and lifetime warranties on selected products. Please see our warranty page for more information.


text:
FiberBuilt Patio Collection 7.5' Umbrella with Crank Handle and Tilt Button - Bronze Frame Model:7HCRCB-T
FiberBuilt Patio Collection 7.5' Umbrella with Crank Handle and Tilt Button - Bronze Frame
From the FiberBuilt Patio Collection, this 7.5' hexagonal umbrella with crank and tilt functions (7HCRCB-T) features a market style canopy that looks sharp and stays stiff, never drooping due to slack or extra hanging fabric. The sturdy aluminum pole, coated in a champagne bronze finish, is equipped with a crank handle that allows for easily raising and lowering the umbrella with the turn of a handle. Once opened, push the button to tilt it into the desired position.
Known for their superior quality and durability, every component of a FiberBuilt umbrella is built to withstand harsh outdoor weather conditions. The flexible fiberglass ribs that support the canopy are designed to bend and absorb strong wind gusts and rain storms, ultimately protecting the umbrella's overall shape and appearance. Atop the durable frame is a thick, olefin material canopy, specifically made to block intense sunlight and resist fading, stains and mildew. Choose to either blend, match or colorfully accent your backyard, poolside or patio furniture decor with our selection of six different canopy colors.
Durability and Longevity:
Molded nylon joints, hubs and tips and a high-grade powder coat finish allow FiberBuilt umbrellas to maintain their appearance for years. Their unique fiberglass rib construction lasts an average of four to five times longer than traditional steel or wood ribbed umbrellasPole Construction:
Constructed of two separate pieces, the thick aluminum pole includes a crank mechanism and a tilt button and generally fits bases 1.5 inches in diameterSix Color Choices:
Available in a variety of color choices including beige, black, forest green, natural, navy blue and pacific blue
Note: This umbrella does not include a stand. Colors may vary.


text:
You are visiting our UK site. Click here to view our US site
Tewa Acupuncture Needles
We are an authorised Tewa retailer. High quality acupuncture needles with stainless steel tips available in various presentations including individual guide tubes, cluster packs, detox packs, copper, steel or plastic handles.
Made in China under German supervision.
Tewa Copper Handle
High quality copper handle acupuncture needles, stainless steel tip wi... [more info]
Tewa Copper Handle Multipack
High quality copper handle acupuncture needles, stainless steel tip wi... [more info]
Tewa Plastic Handle
High quality plastic handle acupuncture needles, stainless steel tip w... [more info]
Tewa Detox Needles
High quality bright plastic handle needles for Detox protocol [more info]
Tewa Intradermal Needles
Intradermal needles are effective for a variety of clinical applicatio... [more info]
Subscribe To CMT
Shopping Basket
Your basket is empty!
Change Language
Change Currency
Events Calendar
Auriculotherapy Seminars - The 2014 UK Weekend Workshops with Jim Chalmers
A brief history of Ear Acupuncture, Anatomy and Enervation of the Ear, Techniques to locate active points, Prioritisation of point selection, TCM integration... [more]
Master Tung Acupuncture with Philip Weeks (22nd/23rd January 2015)
Tung Acupuncture is well known for its quick and spontaneous results... [more]


text:
(09-05-2012 11:44 AM)nineof Wrote: Wow, nice work getting the AJ Green, Mr. 264!!! Awesome looking card all around.
(09-07-2012 08:01 PM)younglover Wrote: Wow! Congrats on getting the mini whale I love all the prestige colors! That set could end up looking absolutely incredible. Looove the Chi Chi
(09-11-2012 08:20 AM)nineof Wrote: Holy poop on the Manning auto!!! Big time pickup there, Mr. 264.
(09-10-2012 07:47 PM)ugameck Wrote: Love the Spahn!
(09-11-2012 10:10 AM)warcraftin Wrote: That is a holy poop SWEET Manning you got there.
(09-15-2012 10:35 AM)nineof Wrote: Really sweet additions, Mr. 264! Two awesome jersey pieces on the SP Authentics. And 50% of the set is bonkers!
(09-17-2012 11:25 AM)0264 roadrunner1964 Wrote: Thanks, T. Wouldn't it be cool to complete it at 100%? I am working a little "variant" angle to try and make that 34 card set complete. But, would love all the 264/s.


text:
Publication Types
Publish Date:
This three-page overview provides a framework for promoting healthy sexuality as an approach to sexual violence prevention. It provides a foundation in defining healthy sexuality and positive characteristics and behaviors and outlines the connection to prevention, social change and support for survivors. Also available in Spanish.


text:
This Week
Rochester's business leaders have highest overall, future confidence.
Matthew Flanigan aims to build Flower City Habitat for Humanity.
When will downtown retail development gain momentum like the office and housing sectors?
Tender Loving Family Care follows a different model than most of its home care agency peers.
Taren Greenidge says helping Littler Mendelson clients do the right thing is rewarding.
See the 20th anniversary edition of the Forty under 40 supplement.
Business & Charitable Events Calendar
- Charitable
- Business
- All
June 7, 2013
- Course—"HR Management Series, Basic" (5/20/2013 - 6/15/2013)
Rochester Business Alliance Inc. - Network International Meeting (6/7/2013)
The Referral Team Chapter of Business - Network International Meeting (6/7/2013)
Mid Day Masters Chapter of Business
« Go back to the detailed calendar. Or go to the annual Charitable Events Calendar special section.


text:
Fishing for Grayling
This was my first time fishing for grayling. So much fun!!! I took my buddy Wil who is new to fly fishing and getting more into it the more he practices and goes out. He had a good time and caught some fish too! Needless to say we are both hooked....who hasnt heard that pun before?


text:
- Flat Rate Shipping. Any Size Order! -
- A Portion of Proceeds Benefit Miami Athletics -
Miami Hurricanes Gear
Miami Hurricanes Accessories
Miami Hurricanes Accessories Ladies
(150 items)
Product ID: 1481866
Main Content
This item ships within one business day.
Order as many items as you like with our $7.99 flat rate shipping.
Need it faster?
Complete your game day look with this Miami Hurricanes quilted saddle bag! Featuring vibrant quilted fabric, this Miami Hurricanes purse by Littlearth also offers additional details like an embroidered applique team logo, magnetic flap closure and internal side pocket. The versatile faux-leather strap expands to 50", so you can wear this as a Hurricanes cross-body purse and keep your hands free to clap during the game!
- Allover quilted pattern
- Embroidered applique patch with team design
- Magnetic flap closure
- Officially licensed
- Quilted saddle bag
Hurricanes Customers also liked:
Special event items are produced by manufacturers only after the outcome of a game
or event. These are advanced sale items and will ship immediately after they are
received in our warehouse.
Manufacturer direct items are shipped directly from the manufacturer. These items
are not available for international or expedited shipping.
Customized items can be personalized with options such as your name, your favorite
number, and/or designs. Some options may be limited by league rules.


text:
Internet Explorer problems can be caused by out-of-date files, incorrect or incomplete registration of files, or because the Desktop or Start menu shortcut of Internet Explorer have been deleted or do not function properly. If your Internet browser is under this situation, you need to uninstall Skype for a new one. If you are not sure what to do, please follow the instructions below.
Download Now - FreeMethod 1
This is how easy it works. However, sometimes it can happen that the uninstall fails. This can be because it simply failed, or because there are some files left on your registry and on your hard-drive that are Skype related. What do you need to do now to uninstall and to remove Skype from your computer?
Method 2
Using an uninstaller with a high reputation is highly recommended. And Best Uninstall Tool is such a program.
Best Uninstall Tool is able to solve all your uninstall problems, including uninstalling of any kinds of Internet software related to:
Chat / IM / SMS
File Sharing
RSS / Podcast / Blog
Telephony / VoIP
Other Internet


text: Style-savvy mums-to-be need look no further for the latest hits of the season. We've rolled super chic dressing and total comfiness into one with our Maternity clothing. From essential skinny jeans to a striking print swimsuit, we've got maternity clothes nailed for expectant mamas - including pieces you can wear once your little one has arrived too. Maternity wear stays totally on trend with Topshop - check out our most lovable looks right now.


text:
Narrow By Clear All
- $375 - $500 (1)
Some items might be eligible for immediate Delivery in your area. Enter your ZIP to check.
- Layaway(1)
- Store Pickup(1)
- Delivery(1)
- Free Delivery(1)
- All Items On Sale (1)
- Buy More Save More (1)
- Companion (1)
- Free Delivery (1)
+Earn Points
Use upright freezers for extra kitchen storage
Upright freezers are a simple, stylish solution when you need more cold storage in the kitchen. The slim style fits right in with your other appliances, allowing you to stock up on more of your favorite foods. Having extra freezer space makes storing homegrown produce a breeze. Sears stocks a variety of stand-up freezers along with other useful appliances and accessories for your kitchen.
The simple act of making ice can take up a lot of room in your freezer, especially if you entertain frequently. Freezer ice makers solve this problem by providing a dedicated space just for making ice. Both freezers and ice makers need regular maintenance to continue operating smoothly. Ice maker cleaner, filters and freezer parts help you keep your appliances in tip-top shape over time.
Outfitting your kitchen with enough freezer space ensures that you'll always have storage space for your favorite frozen foods. At Sears, you'll find both large and small upright freezers, so you can stock up at the store or freeze your own fresh recipes to enjoy any time. Check out this selection to find the right stand-up deep freezer for your kitchen along with the parts to maintain it for years to come.


text:
Use your MavMAIL username and password.
Instant messaging lets you send quick short messages to one or multiple people.
Presence enables real-time status of staff, faculty and students (based on calendar information, login/activity status, and user preference) to be displayed across the University to enable users to contact the right person using a quick chat session.
Available Presence states: Available, Busy, Do Not Disturb, Be Right Back, Away, Appear Offline.
Presence is automatically updated based on your MavMAIL or Outlook Calendar. If you want to change your presence status, you can do so by clicking the small arrow next to the Presence indicator in MavMAIL or Lync.
Double-Click the name of the person you would like to chat with. A pop-up window will appear.
Double-Click the name of the person you would like to chat with. A pop-up window will appear. In the pop-up window you can start typing a message to that person. Notice that IM (Instant Messaging) is selected.
In your chat window, click on the down arrow next to "Share". Then you can select the monitor you would like to share, and this will only display your selection. You can use the same process to share an application. In the chat window, click on the down arrow next to the word "Share" and select your program. A new window will open up, in which you can choose what you would like to share. The other people in your meeting will only see your selection.
In your chat window, click on the down arrow next to "Share" and select "New Poll", which you can name in the "Create a Poll" box. A newly created poll can be used later in an online meeting or chat session. Write your question in the question box, and your offered answer under "Choices". Click 'OK' to start sharing the poll.
After you have Lync installed, there will be a new button in the Outlook rib that says "New Online Meeting" in the calendar view. Click the "New Online Meeting" button.
In the body of your meeting message you will notice some instructions on how to join the meeting. The attendees can join by clicking the "Join online meeting" link, or you can copy the URL to a web browser. You can also join the meeting by phone.
Once you click on the URL to join the meeting, it will automatically launch Lync. If you do not have Lync installed, a web page will open instead, and offer three options:
Joining the meeting with your web browser comes with two options. Join as a guest, which is very useful for attendees who are not students, faculty or staff at Minnesota State University, Mankato. They will have limited functionality in the meeting, but they do have an option to type their name and then click "Join Meeting".
Guests will have to wait in the lobby to be admitted by the presenters who are hosting the meeting. The presenter will have to click on "Admit" in Lync or *8 on their phone to allow everyone in.
Now that everyone has been admitted to the meeting, the meeting can begin. Make sure to look at other sections of the document that discuss joining a meeting using your phone, sharing your desktop or using polls.
To start an Ad-Hoc meeting click on the down triangle settings gear in the upper right hand corner and select "Meet Now". This will start a "Group Conversation". To add people to your Ad-Hoc meeting, you can drag and drop names from the contact list into the group conversation window. If you click on the "Join Information and Meeting Options" link, you will see the details for the meeting. There will be a dial-in number. (507) 389-2800 and a conference ID: ##### followed by a meeting link. The meeting link can be emailed to anyone so they can join the meeting through a web browser.
To attend a meeting using your phone dial (507)389-2800 and then enter the conference ID of the meeting that you would like to join. The conference ID can be found in the "Join Information and Meeting Options" within your meeting or if the meeting information that was emailed to you.
Yes, but you will need to send them the meeting link through email. Once they click on the link, a web page will open. If they have Lync install on the computer, it will automatically start and join them to the meeting. If Lync is not installed, the web page will provide links to join the meeting using the web browser, download and install Lync Attendee or use Microsoft Communicator. Joining the meeting with a web browser will be the easiest option.
Lync Web App or joining a meeting with your web browser will give you basic Lync functionality. You can instant message, share your desktop or share a program. Lync Web App does not have voice or video. However, you can still call into the meeting with a telephone, or if you have enterprise voice enabled with your Lync account, Lync can call you.
Lync Attendee does not have the contact list that Lync has. Lync Attendee cannot initiate meetings. But it still can join meetings with instant messaging, voice, video and program and desktop sharing.
In a group conversation click on the two ">>" near the upper right hand corner and select "Start Recording". This will announce to all participants that the meeting is being recorded.
This will record the following actions in the meeting:
To stop recording, click on the stop button in the lower right hand corner. It looks like a square. Once the recording has stopped, Lync Recording Manager will open or display a balloon message near the clock that Lync Recording Manager is processing the recording. You can also open Lync Recording Manager by using the start menu. Once the status is complete, the recording can be played. The recordings are saved on the local computer running Lync in .wmv format. This format can be play with Windows Media Player.
At this time, Lync can only communicate with other Lync users in our campus organization.
If you would like more information regarding Lync, please contact the ITS Help Desk @ x6654.
MavCHAT is a subset of features available from the Microsoft Lync 2010 Server. Go to http://www.microsoft.com/Lync for more information on Microsoft Lync 2010.


text:
DES MOINES – High water could close portions of Wapsipinicon State Park and affect access while clean-up of past flooding damage will close Wilson Island State Park starting July 1st.
If the forecast is accurate, the Wapsipinicon River is expected to reach a flood stage of 27 feet, one foot higher than the 2008 floods, by Friday. Currently, the Wapsipinicon River is at 17 feet.
Should the Wapsipinicon River reach that depth, the Rotary lodge, playground shelter and the Dutch Creek Shelter at Wapsipinicon State Park in Jones County will be inaccessible due to roads flooding. Depending on if, and how badly these areas are damaged, these areas may be closed during the week of Fourth of July. The Boy Scout Lodge, campground and golf course are not expected to be affected.
The county has closed E-24 until further notice. As a result, Wapsipinicon State Park is only accessible from the south.
Wilson Island, in Pottawattamie County, will also be closed for rebuilding starting July 1st. In addition to extensive cleanup from previous floods, culverts will be added to several roads to improve water drainage. Construction is expected to last until May, 2014.
Other parks affected by flooding include George Wyth State Park, which is expected to reopen July 1st if conditions allow, and the Yellow River Forest campground, which has extensive flood damage. The damage is being assessed by the DNR. There is not yet an expected date for reopening.


text:
This week we hear from Morgan Springsteen, who is currently acting in The Tempest.
As is always true in life, for everything there must be a beginning, for each path a starting point. My interest in theatre stretches back as far as I can remember. However, I remember distinctly the first time I stepped onto a stage and decided, almost instantaneously, that acting was my passion. This production of The Tempest marks another first for me. This is my first time acting in one of Shakespeare's plays. It is an experience unlike anything I have ever had in many ways, some which I have found challenging, all of which I have found exciting.
Working with Pigeon Creek requires a level of self-management that I had not yet experienced working in educational theatre at Grand Valley. A major reason for this is that this show was ensemble directed. Ultimately, what we as actors choose to put on the stage is our choice. However, we are dependent on the cast as a whole to make sure that everything looks cohesive and makes sense. In order to be a functional and effective cog in the machine, you must be willing to take constructive criticism you're your peers and not be afraid to give it out. As a novice to Shakespearean acting, it was difficult at first to pipe up and give direction. However, as my understanding of the process grew, so too did my confidence.
Another thing that sets this experience apart is that I am playing multiple small roles, on top of understudying the role of Ariel. Trying to flesh out the characters of a salty mouthed sailor (the Boatswain), an eager and optimistic lord in the company of the king (Adrian), and a rainbow goddess at the marriage of Ferdinand and Miranda (Iris) requires a keen sense of contrast. It has been fun finding the nuances of each character and discovering what makes each one stand out from the others.
On top of these three parts, it has been an added challenge to keep track and learn all of the things Ariel is in charge of throughout the play. I am still working to find the balance between following the character Kate has fleshed out and still allowing room for my own interpretation. I am excited to tackle the role in a few weeks when we head to Toledo, and I only hope my performance lives up to Kate's.
This truly has been a hugely valuable experience. I'm sure I will find myself comparing this production with new theatre experiences as they come along. I am so glad I got to work with this amazing group of people and put together a show that I not only feel much attached to, but extremely proud of.


text:
tagged with: "rrkidz"
The RRKidz app made its debut on Apple's iTunes in June 2012 and I joined representatives from Holiday House Books, Little Brown and Company, Hachette Book Group, and others for the launch party. Mr. Burton — oh, who am I kidding, he's LeVar! — LeVar and I exchanged good wishes and he thanked ABRAMS for providing, yep, our beautiful books (and it should come as no surprise that I have a newfound interest in Star Trek: Next Generation 365).


text:
Howdy, Stranger!
It looks like you're new here. If you want to get involved, click one of these buttons!
replacment key
i had lost my car key to my ignition and i was woundering if the buick dealership can order me a new key that works for a 1992 buick park ave? the key has to have the chip on it for the secerity system.
imidazol97 Crossroads of America: I70 & I75Posts: 18,643I'm not sure what you are meaning. Are you wanting to bypass the VATS system? This is the security system that reads the key chip resistance and makes sure it's the right amount to match whichever one of 15 choices the car is set to need.
Do you have a key that works? You will need it to read the resistance to know which key will need to be cut to match the cylinder.
autoz Posts: 3I am a proud owner of a 2001 Buick Park Ave (Std., not Ultra}
My fuel gage was pegged so I installed a different speedometer/gage assembly from a 2003 P.A., salvage yard purchase. At this time I also changed the factory radio to a factory radio that has a C.D. player. It appears that the fuel gage and radio function just fine. The problem is that now when I turn the ignition to on, all of the system check light activate, but when I turn the key to start all the display goes out and there is no attempt to start the car. Next I walked the original fuel gage counter-clockwise back to empty and reinstalled the original speedometer cluster. The same symptoms exist, but the fuel gage works. Is there an issue with the Pass key III security system? Please share any thoughts! Thanks, Dave -
imidazol97 Crossroads of America: I70 & I75Posts: 18,643>At this time I also changed the factory radio to a factory radio that has a C.D. player.
I believe the radio is part of the car's security system. I suspect taking it out affected that operation.
Put the original radio back in.
If you change the radio I'll bet it will require a dealer to reset the system. At least it will take someone with
Tech II to do that. -
imidazol97 Crossroads of America: I70 & I75Posts: 18,643Homelink.com has instructions.
You hold the two outside buttons for 20 seconds up to 30 seconds till the red light blinks to clear the settings in all three from the previous owner.
Then you hold your transmitter next to the unit and press the button on the unit and the button on the transmitter. Hold till the light blinks fast. -
imidazol97 Crossroads of America: I70 & I75Posts: 18,643
imidazol97 Crossroads of America: I70 & I75Posts: 18,643If it has a theft deterrent system for the doors and trunk, that may be keeping the light on.
Does it go off when driving?
Try pulling the tamper wire on the trunk lid latch. You may have to pull back the felt covering to find it. Some people have reported a problem with that sensor occurring most often.
You have an earlier system of the anti theft key portion. I believe it's managed by the powertrain computer. After a couple more years, there's a separate theft module for the key check for resistance. You might search for VATS on the net.
I suspect yours is not from the key resistance reading. You haven't mentioned trouble getting the car to crank, which is what would happen if it didn't read the key resistor right. With the later (95 or thereabouts) the key theft portion can fail in 4 modes and one of them is it decides it lost its mind and doesn't prevent the car from starting, but the security light stays on. But on my 98 leSabre the security light never comes on--but I don't have the trunk and door check security stuff on mine (ordered it without, intentionally).
You might try the key portion by turning the key to ON and seeing if the security light comes on for about 5-10 seconds and then goes off. That is what the key portion should do if it's getting the right resistance.
This discussion has been closed.


text:
This User Agreement and Privacy Policy governs each website, mobile site, application, and/or other service, regardless of how distributed, transmitted, published, or broadcast (each, a "Service") provided by Advance Publications, Inc., its parent, subsidiaries and/or affiliates ("we," "us," or "our") that links to this User Agreement and Privacy Policy, which is binding on all those who access, visit and/or use the Service, whether acting as an individual or on behalf of an entity, including you and all persons, entities, or digital engines of any kind that harvest, crawl, index, scrape, spider, or mine digital content by an automated or manual process or otherwise (collectively, "you" or "your").
Please read this User Agreement and Privacy Policy carefully. You can access this User Agreement and Privacy Policy any time in the footer of the Service's home page or initial screen. Your access, visitation and/or use of the Service, including without limitation any registration on any aspect of the Service, will constitute your agreement to this User Agreement and Privacy Policy. If you do not agree with the terms and conditions of this User Agreement and Privacy Policy, you may not access, visit and/or use the Service.
The User Agreement and Privacy Policy may be modified from time to time; the date of the most recent revisions will appear on this page, so check back often. Continued access of the Service by you will constitute your acceptance of any changes or revisions to the User Agreement and Privacy Policy. If you breach, violate, fail to follow, or act inconsistently with the rules, restrictions, limitations, terms and/or conditions that apply to the Service, whether listed in this User Agreement and Privacy Policy, posted at various points in the Service, or otherwise communicated to users of the Service (collectively, the "Agreement"), we may terminate, discontinue, suspend, and/or restrict your account/profile, your ability to access, visit, and/or use the Service or any portion thereof, and/or the Agreement, including without limitation any of our purported obligations hereunder, with or without notice, in addition to our other remedies. In addition, we may curtail, restrict, or refuse to provide you with any future access, visitation, and/or use of the Service. We reserve the right, in addition to our other remedies, to take any technical, legal, and/or other action(s) that we deem necessary and/or appropriate, with or without notice, to prevent violations and enforce the Agreement and remediate any purported violations. You acknowledge and agree that we have the right hereunder to an injunction without posting a bond to stop or prevent a breach or violation of your obligations under the Agreement.
In the event of any conflict or inconsistency between the terms and conditions of this User Agreement and Privacy Policy, and any rules, restrictions, limitations, terms and/or conditions that may be posted at various points in the Service or otherwise communicated to users of the Service, we shall determine which rules, restrictions, limitations, terms and/or conditions shall control and prevail in our sole discretion, and you specifically waive any right to challenge or dispute such determination.
Among other things, the Agreement governs all text, articles, photographs, images, graphics, illustrations, creative, copy, artwork, video, audio, music, podcasts, ringtones, games, trademarks, trade names, service marks, and other brand identifiers, designs, plans, software, source and object code, algorithms, data, statistics, analysis, formulas, indexes, registries, repositories, and all other content, information, and materials (collectively, "Content") available on or through the Service, whether posted, uploaded, transmitted, sent or otherwise made available by us, our licensors, vendors, and/or service providers, or by you, and/or other users or third parties, including any such Content uploaded manually or bookmarked by you and/or other users.
We strive to provide an enjoyable online experience for our users, so we may monitor activity on the Service, including in the social, community and public discussion areas, photo and video galleries, bulletin boards, forums, chats, blogs, personal/job search and other classified ads, and elsewhere, to foster compliance with the Agreement. You hereby specifically agree to such monitoring. Nevertheless, we do not make any representations, warranties or guarantees that: (1) the Service, or any portion thereof, will be monitored for accuracy or unacceptable use, (2) apparent statements of fact will be authenticated, or (3) we will take any specific action (or any action at all) in the event of a challenge or dispute regarding compliance or non-compliance with the Agreement. We generally do not pre-screen Content before it is posted, uploaded, transmitted, sent or otherwise made available on or through the Service by users, so you may be exposed to Content that is opinionated, offensive, and/or inappropriate, including Content that violates the Agreement.
We do not necessarily endorse, support, sanction, encourage, verify, or agree with the comments, opinions, or statements posted, uploaded, transmitted, sent or otherwise made available on or through the Service, including without limitation in our social, community and public discussion areas, photo and video galleries, bulletin boards, forums, chats, blogs, columns, articles, personal/job search and other classified ads, contests/sweepstakes, or elsewhere. Any Content posted, uploaded, transmitted, sent or otherwise made available on or through the Service, including advice and opinions, are the views and responsibility of those who post the Content and do not necessarily represent our views or the views of our licensors, vendors, and/or service providers. You agree that we and our licensors, vendors, and/or service providers are not responsible, and shall have no liability to you, with respect to any Content posted, uploaded, transmitted, sent or otherwise made available on the Service, including Content that violates the Agreement.
We reserve the right, but undertake no duty, in our sole discretion, with or without notice, to review, edit, move, add, delete, or otherwise change any features, functionality, and/or Content available on or through, or downloadable from, the Service, including without limitation any Content in your account/profile, or any of your messages, posts, or threads. This includes updates or upgrades to Content, automatic or otherwise. You agree to accept, and to take no action to interfere with, automatic upgrades or updates. Any changes to the Service may not be consistent across all platforms, computers, or devices. If you do not refresh the Service after each such change, or download the update(s) or upgrade(s), your experience may not reflect the most recent features, functionality, and/or Content, for which we and our Indemnitees disclaim any and all responsibility and liability. If any changes require you to obtain new, additional, or different equipment, hardware, software, and/or telephone, mobile, wireless, Internet and/or other services, you are solely responsible for any additional expense. Even after Content is removed from your account/profile, your messages, post(s), and/or threads, regardless of whether such removal or deletion is by you or by us, copies of that Content may be retained and/or remain viewable by us, our licensors, vendors, service providers and/or other third parties, including other users.
Jerry Birenz, Esq. | |
Sabin, Bermant & Gould LLP | Phone: (212) 381-7057 |
4 Times Square, 23rd Floor | Fax: (212) 381-7201 |
New York, NY 10036-6526 | E-mail: email@example.com |
Note: Only copyright complaints should be sent to agent. No other communications will be accepted or responded to.
For communications on other matters, please contact us through the means described on the Service, if available (for example, in the "Contact Us" section), or if no such means are specified, contact our Privacy Policy Coordinator as described in our Privacy Policy.
You agree to indemnify, defend and hold harmless us, our licensors, vendors, service providers, and each of our and their respective officers, directors, members, employees, independent and sub-contractors, agents, representatives, successors and assigns (collectively, "Indemnitees") from and against any and all claims, disputes, demands, proceedings, cause of action, judgments, damages, liabilities, losses, costs or expense (including, but not limited to reasonable attorneys' fees) of any kind and nature, known and unknown, suspected and unsuspected, disclosed and undisclosed (collectively, "Claims") which may arise out of or are in any way connected with your access, visitation and/or use of the Service, your Content, unauthorized use of Content obtained on or through the Service, breach or alleged breach of the Agreement, or from any of your acts or omissions in connection with the Service.
The following provision applies to all visitors (which shall include persons and representatives of legal entities, whether such representatives are persons or digital engines of a kind that crawls, indexes, scrapes, copies, stores or transmits digital content). By accessing this Web site or digital service, you specifically acknowledge and agree that: (i) Associated Press text, photo, graphic, audio and/or video material shall not be published, broadcast, rewritten for broadcast or publication or redistributed directly or indirectly in any medium, and shall be subject to all terms and conditions made available at the AP Terms and Conditions web page available here http://www.ap.org/termsandconditions/ ; (ii) No Associated Press materials nor any portion thereof may be stored in a computer except for personal and non-commercial use; (iii) The Associated Press will not be held liable for any delays, inaccuracies, errors or omissions therefrom or in the transmission or delivery of all or any part thereof or for any damages arising from any of the foregoing; (iv) The Associated Press is an intended third party beneficiary of these terms and conditions and it may exercise all rights and remedies available to it; and (v) The Associated Press reserves the right to audit possible unauthorized commercial use of AP materials or any portion thereof at any time.
You understand and agree that various entities unaffiliated with us make up the "mobile ecosystem" that enables you to access, visit and/or use the Service via your computer, mobile or other device, including without limitation equipment, hardware and software manufacturers and providers, telephone, mobile, wireless, and Internet network providers and carriers, and sellers or providers of Content for use with the Service (collectively, the "Mobile Participants"). We do not represent, warrant or guarantee that all portions of the Service, or the Service as a whole, can be accessed via all mobile or other devices, or via all carriers and service plans or is available in all geographic locations. THESE MOBILE PARTICIPANTS MAY REQUIRE THAT YOU AGREE TO THEIR ADDITIONAL TERMS, CONDITIONS, CONTRACTS, AGREEMENTS AND/OR RULES. YOUR COMPLIANCE WITH ANY SUCH ADDITIONAL TERMS, CONDITIONS, CONTRACTS, AGREEMENTS AND/OR RULES IS SOLELY YOUR RESPONSIBILITY AND WILL HAVE NO EFFECT ON YOUR CONTINUING OBLIGATION TO COMPLY WITH THE AGREEMENT WHEN USING THE SERVICE. WE AND OUR INDEMNITEES SPECIFICALLY DISCLAIM ANY AND ALL LIABILITY IN CONNECTION WITH THE ACTS OR OMISSIONS OF SUCH MOBILE PARTICIPANTS. We have agreements with some of these Mobile Participants that require us to make certain disclosures and pass along certain responsibilities to you. For such Mobile Participants, you specifically acknowledge and agree that: (i) the Agreement is between us and you; the Mobile Participants are not parties to the Agreement; (ii) the Mobile Participants and their parent, subsidiaries and affiliates are third party beneficiaries of the Agreement and upon your acceptance of the terms and conditions of the Agreement, the Mobile Participants will have the right (and will be deemed to have accepted the right) to enforce the Agreement against you; (iii) the license granted to you hereunder is limited to a non-transferable license to use the Service on the particular product authorized by the applicable Mobile Participant that you own or control and as permitted by such Mobile Participant's applicable usage rules; (iv) Mobile Participants have no obligation whatsoever in connection with the functionality or content of the Service, or to furnish any maintenance or support services with respect to the Service; (v) in the event of any failure of the Service to conform to any applicable warranty, you may be able to notify the applicable Mobile Participant to receive a refund of all or part of the amount you paid for the Service, if any (to the maximum amount permitted by applicable law, Mobile Participants will have no other warranty obligation whatsoever with respect to the Service); (vi) Mobile Participants are not responsible for addressing any claims, losses, liabilities, damages, costs or expenses by you or a third party relating to the Service or your possession, access, visitation and/or use of the Service, including without limitation (a) product liability claims; (b) any claim that the Service fails to conform to any applicable legal or regulatory requirement; and (c) claims arising under consumer protection or similar legislation; and (vii) in the event of any third party claim that the Service or your possession, access, visitation and/or use of the Service, infringes such third party's intellectual property rights, Mobile Participants are not responsible for the investigation, defense, settlement and/or discharge of such claim.
Your information may be transferred to, and maintained on, servers and databases located outside of your state, province, country or other governmental jurisdiction where the privacy laws may not be as protective as your jurisdiction. Please be advised that we may transfer your information to and from any state, province, country or other governmental jurisdiction, and process it in the United States or elsewhere. Your consent to this Privacy Policy followed by your submission of such information represents your agreement to any such transfer.
This Web site uses services provided by News Registry. News Registry collects content usage information and may use cookies in conjunction with this activity. Your continued readership of the Site means you accept the privacy policy of the News Registry. Please refer to the News Registry privacy policy at http://www.apnewsregistry.com/privacycenter/servicepolicy.aspx for further information.
If you have any concerns or questions about any aspect of this policy, please feel free to contact our Privacy Policy Coordinator as follows:
Make sure to include enough information for us to help you, including for example your name, contact information, and the specific website, mobile site, application, and/or other service you're contacting us about.
Note: Only inquiries about this policy or your personal information should be sent to the Privacy Policy Coordinator. No other communications will be accepted or responded to.
For communications on other matters, please contact us through the means described on the Service, if available (for example, in the "Contact Us" section).


text:
The most under-appreciated erogenous zone for both men and women alike just might be the nipples. But you're really missing out if you're not paying your pinkies enough attention during sex. Stimulating your nipples, whether with light tickling, licking, sucking or pinching, can push your arousal over the edge and intensify your orgasms. So, the next time you get down and dirty, don't forget to let your nips be involved in the fun!
Adam & Eve carries an assortment of toys to meet all your nipple-pleasing needs. Nipple pumps suck your nipples so they're nice and hard. Nothing tells your partner you're turned on and ready to play quite like erect nipples. Plus, all that blood flow to those tightly packed nerves means increased sensitivity! Our nipple clamps and teasers are each designed to maximize arousal, delivering just the right amount of pressure to drive you or your lover wild.
Take that sensation to a whole new level with vibrating nipple clamps and nipple massagers, which are easy to control and have varying levels of vibration to keep you satisfied. We also have nipple clamps with fun accessories, like bells and feathers, so you can get creative with your foreplay.
For BDSM enthusiasts, Adam & Eve has several nipple toys designed to incorporate just the right amount of pleasurable pain to your nipple play—from weighted nipple clamps, to clamps that deliver a small shock. And with nipple clamps outfitted with chains that attach to collars and clit clamps you can achieve both the look and feel of your kinkiest fantasies.
For the softer side of nipple play, try a nipple tickler. These tickle your nipples until you can't stand it anymore and need something harder to satiate your needs!
For the ladies, we also have breast enlargers that give your titties the porn-star treatment. You will love how extra sensitive your ta-tas are and your partner will love putting your big breasts in his or her mouth.
With so many options, there's no reason to neglect your precious headlights!


text:
This is the home page for the Maven users space. Where users can contribute documentation for others users and for incorporation into the main site. Any users with outside documentation should share it with others here. This is our sandbox and it's only as good as we make it.
Just for fun.... A song for Maven's developers: Got My Mojo Working
All information in this wiki is licensed under the Apache License, version 2.0. Please keep this in mind when you contribute.
Table of Contents
- Scala and Maven
- Maven Day at Intuit (Thursday October 9th)
- Maven Patch Day
- Getting Started with Maven
- Maven Best Practice Guide
- Proposed Documentation
- Enterprise Maven
- Examples
- MavenPlugins
- Maven Skins
- Mini Guides
- Archived Docs
- Nexus Maven Repository Manager
- Archiva
- Continuum
- Doxia
- Surefire
- User Proposals
- Utilities
- Solving the Skinny Wars problem
- Tomcat
- Using Maven to manage .NET projects
This wiki space is not for final documentation, but a workspace for creating it. If you think a document can be contributed back to the main site, please record that in JIRA. For discussions, ideas and design documents related to Maven, see the Maven space.
If you're a java Java software developer that 's has worked in any type of team situationenvironment, you know that the having a proper process is important to developing a quality product. Also, you You also know , that rote methods can help maintain consistency and standardization among developers. Apache ANT does that for some of us very well. Maven kicked it up a notch provides most of this however Maven improves upon it in several areas. Maven took takes some of that classpath and jar dependency frustration frustrations out of the hands of the day-to-day developer. Most will would agree with me that maintaining the project structure, dependencies, J2EE packaging, etc. is very difficult . When and when things are not structured correctly, applications don't workcannot be built properly. Jars could be in the wrong place, jars could be the wrong version, an XML file might be missing a descriptor, and a host of other project infrastructure issues can bring a project to stop. When this happens it's its sometimes difficult to determine where things are wrong. And, most developers aren't up on all their J2EE archive types. Nor do they focus on the trivia of J2EE descriptors. Developers went wrong. Maven is an excellent tool that solves most of these problems.
While the stereotypical typical project manager might disagree with me, Maven meets the project manager and the development staff somewhere in the middle. Apache's ANT is a powerful tool, but there's no standardization in targets. In fact, it may be too customizable. Maven did right by holding to a distinct set of build lifecycle goals. If you're the do-it-yourself type, you can create your own plugins to extend the functionality of Maven. Project managers want control and Maven injects this technical control into the build process. Maven assures everyone that the build and deploy process is done the same everytime. Musician's every time. Musicians practice scale repetition for this very reason. Rote processes that work are very effective because their commonality consistency and effectiveness save time and assure quality.
Want to write a wiki documentation but don't know where to put it? - Write it first here, then let's transfer it latterlater.
Other material
Material on Maven 2, outside the maven site.
- Working with Maven 2: bullet-type course notes
- Testing strategies with Maven 2: Notes on testing strategies
- Maven related materials: Articles, books, extensions, IDEs, tutorials.
- Development by Example: Maven & Archiva


text:
The air monitoring network plan will assist the Iowa DNR in its efforts to monitor the quality of Iowa's air and to keep the public aware of air quality problems. The plan is required by EPA's national ambient air monitoring regulations. It contains detailed information about the location and purpose of any monitor in Iowa's air monitoring network that produces data for comparison with national ambient air quality standards. Errors in the lead emissions estimates were noted in the network plan posted on 5/30/13. The revised plan contains the corrected lead emissions estimates. The plan and comments will be submitted to EPA after a 30 day review period.
The Air Quality Bureau must receive all public comments by July 1, 2013. Written comments may be sent by regular mail to: Sean Fitzsimmons Lead Worker Ambient Air Monitoring Section Iowa Air Quality Bureau 7900 Hickman Road, Suite 1 Windsor Heights, Iowa 50324
or by email to email@example.com. Please include "2013 Air Monitoring Network Plan" in the subject line of the e-mail. This list serve article is intended for consultants, industries, environmental groups, general public, and other entities regulated under the Clean Air Act. It was written by the DNR Air Quality Bureau to share regulatory news, program updates and technical guidance.


text:
1st summer bath
This photo was shot on film. Taken by disdis with a Lomo LC-A+ RL (available in our Online Shop) loaded with Kodak Elitechrome ED film (available in our Online Shop) in Durana, Spain. These tags describe this photo: vitoria, disdis, krab, water, underwater, doubles, double, myself, portrait, selfportrait, xpro, ed200, lca, lc-a, rl, textures, numbers, numero, summer, verano, hot, bath, baño, feria, fair, x-pro, and 35mm. Date: 2012-08. This photo can also be found in the album Doubles with numbers and textures.Please login to get more out of this site
You are currently not logged in, do so now to add comments, like articles as well as photos, submit to competitions, translate articles and gain access to unlimited photo upload! If you are not registered yet, go here to find out more about Lomography and join now! If you just want a limited account for now you can use Twitter or Facebook. We would love to have you as a member here!
24 people like this photo
Liking photos helps us to present the best ones to you and others. 24 people like this photo. 24 people like this photo: gilemilio, mariskaviska, japsix, hhjm, clickiemcpete, isabel_mebarak, grazie, snailish, ripsta, fisher-price, lilithmoon, red_constructor, minilidia, warning, atria007, tennisguy, aexel, maria_vlachou, why-yu, rik041, emkei, aoizumi, mafiosa, and lomomowlem.
No comments yet, be the first
Where is this?
Nearby popular photos – see more
Nearby LomoLocations
Santa Isabel Graveyard - 200 Years of Death
A place full of heroin addicts, tomb raiders, pagan rites. Rumors or truth? Anyway, it's sti…
El Boulevard de Euskal Herria - The MALL
20 years ago, the mayor of Vitoria was against the big malls. Now, after he retired 11 years…
Cantón de la Soledad - Escalators to The Past
In 2007, the old part of the city which is in a hill, became accessible for everyone.
Vitoria Gazteiz Jazz Festival - Free Concerts Everywhere
Once a year, during two weeks, all the city looks like an open air stage for jazz musicians!


text:
Eligible Bradley County residents may come in and pick up their commodity allocations under the USDA Temporary Emergency Food Assistance Program.
This shipment is scheduled to be distributed at the Bradley-Cleveland Community Services Agency, 155 6th St. S.E., from 9 a.m. to noon or until supplies are exhausted.
Appointments have been scheduled for this distribution; therefore, clients will be seen according to the appointment listed on the back of their Red card issued during the last distribution. New cards were issued in October.
Applicants who wish to have their commodities picked up for them must send their authorized representatives. If this person is not available, they must send a note authorizing the individual to pick up their commodities.
Individuals who do not already have Red commodity cards may come in after 1 p.m. and pickup any remaining commodities. They must bring the necessary information to prove eligibility.
Household categories which are eligible to receive the commodities, are as follows: Food Stamp recipient; Families First (former AFDC program) recipients; SSI (Supplemental Security Income) recipients; income not exceeding the poverty guidelines; public housing; and lieap (Low-Income Energy Assistance Program) recipients.
Households may prove they meet the criteria by bringing one of the following documents of proof: Food stamps — letter of approval, identification card or inert card that comes form Stamps; Families First — Letter of approval and Families First identification card; SSI — Letter of approval or letter form Social Security; Low-income household — income information; public housing — Address identification.
If a person is picking up the commodities for someone else, he or she must bring a note from the recipient saying he is a predetermined amount of each commodities as long as they last.
Recipients are urged to bring two grocery bags with them. Households should remember that misrepresentation of need, or exchange of USDA commodities are prohibited and could result in a fine, imprisonment or both.


text:
sign up to receive exclusive offers and men's wardrobe tips.
new subscribers join and receive $10 off your purchase of $50 or more.
You are now subscribed to receive exclusive offers and new collection & product updates from Paul Fredrick.
Click to update your preferences or continue shopping.
new subscribers join and receive $10off your purchase of$50 or more.
Wool pants are a wardrobe staple, so finding the right fit is essential. All men's wool pants from Paul Fredrick are guaranteed to fit. If not, exchange them for free. Paul Fredrick has men's wool pants, both casual and dress for all occasions.


text:
January 29, 2015
Refine Your Results
"The hottest musical on Broadway" -The New York Times
Click here for details.
Contact Us | Advertise: Rates & Media Kit | Privacy Policy
Send questions and comments to the Webmaster Copyright © 2015 Playbill, Inc. All Rights Reserved.
Free Membership Exclusive Ticket Discounts


text: By Mike Swanger(Orrville, OH) With both tracks having highly competitive fields of Super Late Models with many of the regions best drivers competing at both tracks in the past and now with NAPA Wayne County Speedway switching to Saturday night racing in 2014, Promoters John Bores of Attica Raceway Park along with Jason and Kristin Flory of NAPA Wayne County Speedway announce the formation of an eight race Super Late Model Challenge Series this season. Each track will hold four races during the season with each race paying $1,500 to win and $200 to start the feature with $60 for all non transfer cars. The Late Model Challenge Series will have it's own point fund as a title sponsor is still being sought and a $10 entry fee for each race will be charged and added to the point fund. The first night for the Late Model Challenge Series will be on Friday, May 2nd at Attica Raceway Park with the series in action the next night, Saturday, May 3rd at NAPA Wayne County Speedway. Attica Raceway Park will host the next two night for the series on Friday, June 20th and again on Friday, July 11th as NAPA Wayne County Speedway will resume the series on Saturday, July 12th and then on Saturday, August 9th. The final weekend for the series will be double points at both tracks as Attica Raceway Park will run on Saturday, August 30th and the final race will be on Sunday, August 31st at Napa Wayne County Speedway. A tire rule will be in effect for both tracks with American Racers 44 or harder and Hoosier 1300, LM 20 or harder that will be allowed as each track will run their regular rules and race procedures. Watch for further information about the Late Model Challenge Series and for more information on both tracks, go to their websites at www.atticaracewaypark.com and www.waynecountyspeedway.com.


text:
Home | Products | Search | Gadget of the Month | What's New | Gift Registry | Stores | Contact Us | My Basket
Sonoma Ivory Dinnerware Cereal Bowl (750575) |
$7.16 |
Add to Basket
Sonoma dinnerware is uniquely pleasing. The hand-applied glazes are rich in color and soft in appearance, with visible brush strokes, lending a warmth to your table and providing an appealing backdrop to food. Sonoma dinnerware is as practical and durable as it is attractive, made of rugged ironstone that's safe in the microwave and dishwasher.
Sonoma dinner plates measure 11" in diameter, salad plates 8.25", cereal bowls 6", and rim soup bowls 10". The mug has a 14 oz. capacity, the round platter is 14" in diameter, the serving 13.5" in dia. and the oval platter is 18" long. Special dinnerware shipping charges apply. |


text:
Nothing is more unique and private than your home, isn't it? The place where you are going to dwell, where your kids will grow up, where each day will add your own little world, new memories, the place which is your house. So the endeavour to assemble it must be put in attentive, experienced and well, perfect hands. You must realize that it is wholly your responsibility explain to them what you desire to be done, and completely to find the best home builders for yourself.
Before you let them convert it to a reality, your idea should be clear to you first, they'll work exactly what you want and as instructed, so make sure that your instructions are clear. If you can't get your point through to them and then whine once the job is done, so be attentive and thorough while preparation it would be no great. Do your research well on the kind of home you desire, ask your relatives and friends for his or her ideas, search on the net, keep your options and mind open. Once the preparation period is over, only then start home builder hunting.
Auckland master builders are the proficient individuals who build houses which are comparable in dimension, superiority, and attribute to your home you desire. They'll let you know how much per square foot they usually charge for the building. They could also provide you of what your eyesight residence may rate an estimated layout. Though, it is vital to comprehend exactly what's built-in in the price. If you inquire on some well-established or only new home builders, they are going to give you a list of presentation from the resources they use in constructing new houses for sale.
The instant you think of doing any alteration to your house, you would like to make sure that you only leave it. When making such a major difference to your own house, you're sure to be willing to spend the extra cash to make sure that you've got a job nicely done. For this reason it is vital to trust in Auckland master builders who can give your house all the effects that you desire.
There are different aspects to custom home construction. Some individuals might need to have their house. Using expertise and the skills of specialists in new construction will enable you to optimize the space that you have accessible, and also add it and a generous touch of style. Others may desire parts of their house altered. That is something which is not totally broaden, and desires the work of someone who can comprehend your space, give you what you're looking for and add an awareness of uniformity to the full job. The third is not being unable to rehabilitate houses which are weathered with age or have either been damaged. Having the ability to retain the good parts and build about what needs help is one thing that demands plenty of skill.
Master builders in Auckland are dream fulfillers. Individuals who hope to find themselves in a situation where they may be living in a house they helped to design and construct themselves can value the importance of finding a team of professionals who can make it happen. The truth is that there are numerous organizations willing to tell you they can allow you to build a house which is everything you dreamed it could be. However, not many can finally create for you just what you are thinking about. This can be an enormous investment of your money and time. Getting it right is crucial, and it's something the appropriate team should have the ability to do for you.
Remember that the exact same services are not provided by all master builders. There are several communities which are located in rural areas, while you might want to reside in a property that provides you with easy use of city life, schools and other amenities. As you tour the communities, take into consideration what your goals are for you and your family. Envision where you want to put roots down and raise your family. If you see a community that you just feel is what you've been looking for, do not hesitate to begin the process of having your house built. Once everything is done and you might have moved in, you will see and experience how good it feels to stay in a place which you helped layout. You won't have any regrets, because you didn't have to sacrifice your desires. By picking an excellent team of Auckland master builders, you could cut costs and get everything you needed in your new house.


text:
To place an Honor with Books order you may complete the following information to pay by credit card.
Check payments - click here for a PDF order form.
We would like to notify the Honoree about your gift. You may leave these fields blank if you do not want the Honoree to be notified by the Library.


text:
From Proteopedia
| |||||
4ago, resolution 1.45Å () | |||||
Ligands: | , | ||||
Related: | 2biq, 1dt7, 2ybg, 1uol, 2j1x, 2foj, 2b3g, 2bin, 1olh, 1tsr, 1pes, 2j21, 2gs0, 2j0z, 2x0v, 1c26, 1sal, 1kzy, 1xqh, 2fej, 1a1u, 2ahi, 3sak, 2wgx, 1saf, 2foo, 2bio, 2ydr, 1olg, 2j11, 2bip, 1pet, 2j1y, 1jsp, 1ma3, 2x0w, 2xwr, 2vuk, 1aie, 2h1l, 1saj, 1tup, 1hs5, 2ata, 2x0u, 1ycq, 1gzh, 1sah, 2bim, 1ycr, 2j10, 2ady, 1sak, 1sae, 2j1z, 1ycs, 2ac0, 2j20, 1h26, 2j1w, 4agm, 4agq, 4agl, 4agn, 4agp | ||||
| |||||
Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||
Coordinates: | save as pdb, mmCIF, xml |
Contents |
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174
The destabilizing p53 cancer mutation Y220C creates a druggable surface crevice. We developed a strategy exploiting halogen bonding for lead discovery to stabilize the mutant with small molecules. We designed halogen-enriched fragment libraries (HEFLibs) as starting points to complement classical approaches. From screening of HEFLibs and subsequent structure-guided design, we developed substituted 2-(aminomethyl)-4-ethynyl-6-iodophenols as p53-Y220C stabilizers. Crystal structures of their complexes highlight two key features: (i) a central scaffold with a robust binding mode anchored by halogen bonding of an iodine with a main-chain carbonyl and (ii) an acetylene linker, enabling the targeting of an additional subsite in the crevice. The best binders showed induction of apoptosis in a human cancer cell line with homozygous Y220C mutation. Our structural and biophysical data suggest a more widespread applicability of HEFLibs in drug discovery.
Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53., Wilcken R, Liu X, Zimmermann MO, Rutherford TJ, Fersht AR, Joerger AC, Boeckler FM, J Am Chem Soc. 2012 Apr 18;134(15):6810-8. Epub 2012 Apr 5. PMID:22439615
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
[P53_HUMAN] Note=TP53 is found in increased amounts in a wide variety of transformed cells. TP53 is frequently mutated or inactivated in about 60% of cancers. TP53 defects are found in Barrett metaplasia a condition in which the normally stratified squamous epithelium of the lower esophagus is replaced by a metaplastic columnar epithelium. The condition develops as a complication in approximately 10% of patients with chronic gastroesophageal reflux disease and predisposes to the development of esophageal adenocarcinoma. Defects in TP53 are a cause of esophageal cancer (ESCR) [MIM:133239]. Defects in TP53 are a cause of Li-Fraumeni syndrome (LFS) [MIM:151623]. LFS is an autosomal dominant familial cancer syndrome that in its classic form is defined by the existence of a proband affected by a sarcoma before 45 years with a first degree relative affected by any tumor before 45 years and another first degree relative with any tumor before 45 years or a sarcoma at any age. Other clinical definitions for LFS have been proposed (PubMed:8118819 and PubMed:8718514) and called Li-Fraumeni like syndrome (LFL). In these families affected relatives develop a diverse set of malignancies at unusually early ages. Four types of cancers account for 80% of tumors occurring in TP53 germline mutation carriers: breast cancers, soft tissue and bone sarcomas, brain tumors (astrocytomas) and adrenocortical carcinomas. Less frequent tumors include choroid plexus carcinoma or papilloma before the age of 15, rhabdomyosarcoma before the age of 5, leukemia, Wilms tumor, malignant phyllodes tumor, colorectal and gastric cancers.[1][2][3][4][5][6][7][8][9][10] Defects in TP53 are involved in head and neck squamous cell carcinomas (HNSCC) [MIM:275355]; also known as squamous cell carcinoma of the head and neck. Defects in TP53 are a cause of lung cancer (LNCR) [MIM:211980]. LNCR is a common malignancy affecting tissues of the lung. The most common form of lung cancer is non-small cell lung cancer (NSCLC) that can be divided into 3 major histologic subtypes: squamous cell carcinoma, adenocarcinoma, and large cell lung cancer. NSCLC is often diagnosed at an advanced stage and has a poor prognosis. Defects in TP53 are a cause of choroid plexus papilloma (CPLPA) [MIM:260500]. Choroid plexus papilloma is a slow-growing benign tumor of the choroid plexus that often invades the leptomeninges. In children it is usually in a lateral ventricle but in adults it is more often in the fourth ventricle. Hydrocephalus is common, either from obstruction or from tumor secretion of cerebrospinal fluid. If it undergoes malignant transformation it is called a choroid plexus carcinoma. Primary choroid plexus tumors are rare and usually occur in early childhood.[11] Defects in TP53 are a cause of adrenocortical carcinoma (ADCC) [MIM:202300]. ADCC is a rare childhood tumor of the adrenal cortex. It occurs with increased frequency in patients with the Beckwith-Wiedemann syndrome and is a component tumor in Li-Fraumeni syndrome.[12] Defects in TP53 are the cause of susceptibility to basal cell carcinoma 7 (BCC7) [MIM:614740]. A common malignant skin neoplasm that typically appears on hair-bearing skin, most commonly on sun-exposed areas. It is slow growing and rarely metastasizes, but has potentialities for local invasion and destruction. It usually develops as a flat, firm, pale area that is small, raised, pink or red, translucent, shiny, and waxy, and the area may bleed following minor injury. Tumor size can vary from a few millimeters to several centimeters in diameter.[13]
[P53_HUMAN] Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; te function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.[14][15][16][17][18][19][20][21][22][23][24]
About this Structure
4ago is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
- Wilcken R, Liu X, Zimmermann MO, Rutherford TJ, Fersht AR, Joerger AC, Boeckler FM. Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53. J Am Chem Soc. 2012 Apr 18;134(15):6810-8. Epub 2012 Apr 5. PMID:22439615 doi:10.1021/ja301056a
- Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838
- ↑ Chehab NH, Malikzay A, Stavridi ES, Halazonetis TD. Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13777-82. PMID:10570149
- ↑ Law JC, Strong LC, Chidambaram A, Ferrell RE. A germ line mutation in exon 5 of the p53 gene in an extended cancer family. Cancer Res. 1991 Dec 1;51(23 Pt 1):6385-7. PMID:1933902
- ↑ Malkin D, Li FP, Strong LC, Fraumeni JF Jr, Nelson CE, Kim DH, Kassel J, Gryka MA, Bischoff FZ, Tainsky MA, et al.. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science. 1990 Nov 30;250(4985):1233-8. PMID:1978757
- ↑ Srivastava S, Zou ZQ, Pirollo K, Blattner W, Chang EH. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature. 1990 Dec 20-27;348(6303):747-9. PMID:2259385 doi:http://dx.doi.org/10.1038/348747a0
- ↑ Felix CA, Nau MM, Takahashi T, Mitsudomi T, Chiba I, Poplack DG, Reaman GH, Cole DE, Letterio JJ, Whang-Peng J, et al.. Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia. J Clin Invest. 1992 Feb;89(2):640-7. PMID:1737852 doi:http://dx.doi.org/10.1172/JCI115630
- ↑ Malkin D, Jolly KW, Barbier N, Look AT, Friend SH, Gebhardt MC, Andersen TI, Borresen AL, Li FP, Garber J, et al.. Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms. N Engl J Med. 1992 May 14;326(20):1309-15. PMID:1565144 doi:http://dx.doi.org/10.1056/NEJM199205143262002
- ↑ Frebourg T, Barbier N, Yan YX, Garber JE, Dreyfus M, Fraumeni J Jr, Li FP, Friend SH. Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome. Am J Hum Genet. 1995 Mar;56(3):608-15. PMID:7887414
- ↑ Varley JM, McGown G, Thorncroft M, Tricker KJ, Teare MD, Santibanez-Koref MF, Martin J, Birch JM, Evans DG. An extended Li-Fraumeni kindred with gastric carcinoma and a codon 175 mutation in TP53. J Med Genet. 1995 Dec;32(12):942-5. PMID:8825920
- ↑ Luca JW, Strong LC, Hansen MF. A germline missense mutation R337C in exon 10 of the human p53 gene. Hum Mutat. 1998;Suppl 1:S58-61. PMID:9452042
- ↑ Guran S, Tunca Y, Imirzalioglu N. Hereditary TP53 codon 292 and somatic P16INK4A codon 94 mutations in a Li-Fraumeni syndrome family. Cancer Genet Cytogenet. 1999 Sep;113(2):145-51. PMID:10484981
- ↑ Rutherford J, Chu CE, Duddy PM, Charlton RS, Chumas P, Taylor GR, Lu X, Barnes DM, Camplejohn RS. Investigations on a clinically and functionally unusual and novel germline p53 mutation. Br J Cancer. 2002 May 20;86(10):1592-6. PMID:12085209 doi:10.1038/sj.bjc.6600269
- ↑ Ribeiro RC, Sandrini F, Figueiredo B, Zambetti GP, Michalkiewicz E, Lafferty AR, DeLacerda L, Rabin M, Cadwell C, Sampaio G, Cat I, Stratakis CA, Sandrini R. An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9330-5. PMID:11481490 doi:10.1073/pnas.161479898
- ↑ Stacey SN, Sulem P, Jonasdottir A, Masson G, Gudmundsson J, Gudbjartsson DF, Magnusson OT, Gudjonsson SA, Sigurgeirsson B, Thorisdottir K, Ragnarsson R, Benediktsdottir KR, Nexo BA, Tjonneland A, Overvad K, Rudnai P, Gurzau E, Koppova K, Hemminki K, Corredera C, Fuentelsaz V, Grasa P, Navarrete S, Fuertes F, Garcia-Prats MD, Sanambrosio E, Panadero A, De Juan A, Garcia A, Rivera F, Planelles D, Soriano V, Requena C, Aben KK, van Rossum MM, Cremers RG, van Oort IM, van Spronsen DJ, Schalken JA, Peters WH, Helfand BT, Donovan JL, Hamdy FC, Badescu D, Codreanu O, Jinga M, Csiki IE, Constantinescu V, Badea P, Mates IN, Dinu DE, Constantin A, Mates D, Kristjansdottir S, Agnarsson BA, Jonsson E, Barkardottir RB, Einarsson GV, Sigurdsson F, Moller PH, Stefansson T, Valdimarsson T, Johannsson OT, Sigurdsson H, Jonsson T, Jonasson JG, Tryggvadottir L, Rice T, Hansen HM, Xiao Y, Lachance DH, O Neill BP, Kosel ML, Decker PA, Thorleifsson G, Johannsdottir H, Helgadottir HT, Sigurdsson A, Steinthorsdottir V, Lindblom A, Sandler RS, Keku TO, Banasik K, Jorgensen T, Witte DR, Hansen T, Pedersen O, Jinga V, Neal DE, Catalona WJ, Wrensch M, Wiencke J, Jenkins RB, Nagore E, Vogel U, Kiemeney LA, Kumar R, Mayordomo JI, Olafsson JH, Kong A, Thorsteinsdottir U, Rafnar T, Stefansson K. A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet. 2011 Sep 25;43(11):1098-103. doi: 10.1038/ng.926. PMID:21946351 doi:10.1038/ng.926
- ↑ Schneider E, Montenarh M, Wagner P. Regulation of CAK kinase activity by p53. Oncogene. 1998 Nov 26;17(21):2733-41. PMID:9840937 doi:10.1038/sj.onc.1202504
- ↑ Guo A, Salomoni P, Luo J, Shih A, Zhong S, Gu W, Pandolfi PP. The function of PML in p53-dependent apoptosis. Nat Cell Biol. 2000 Oct;2(10):730-6. PMID:11025664 doi:10.1038/35036365
- ↑ Louria-Hayon I, Grossman T, Sionov RV, Alsheich O, Pandolfi PP, Haupt Y. The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation. J Biol Chem. 2003 Aug 29;278(35):33134-41. Epub 2003 Jun 16. PMID:12810724 doi:10.1074/jbc.M301264200
- ↑ An W, Kim J, Roeder RG. Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53. Cell. 2004 Jun 11;117(6):735-48. PMID:15186775 doi:10.1016/j.cell.2004.05.009
- ↑ Ghosh A, Stewart D, Matlashewski G. Regulation of human p53 activity and cell localization by alternative splicing. Mol Cell Biol. 2004 Sep;24(18):7987-97. PMID:15340061 doi:10.1128/MCB.24.18.7987-7997.2004
- ↑ Zhao Y, Katzman RB, Delmolino LM, Bhat I, Zhang Y, Gurumurthy CB, Germaniuk-Kurowska A, Reddi HV, Solomon A, Zeng MS, Kung A, Ma H, Gao Q, Dimri G, Stanculescu A, Miele L, Wu L, Griffin JD, Wazer DE, Band H, Band V. The notch regulator MAML1 interacts with p53 and functions as a coactivator. J Biol Chem. 2007 Apr 20;282(16):11969-81. Epub 2007 Feb 22. PMID:17317671 doi:M608974200
- ↑ Taira N, Nihira K, Yamaguchi T, Miki Y, Yoshida K. DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage. Mol Cell. 2007 Mar 9;25(5):725-38. PMID:17349958 doi:10.1016/j.molcel.2007.02.007
- ↑ Allton K, Jain AK, Herz HM, Tsai WW, Jung SY, Qin J, Bergmann A, Johnson RL, Barton MC. Trim24 targets endogenous p53 for degradation. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11612-6. doi:, 10.1073/pnas.0813177106. Epub 2009 Jun 25. PMID:19556538 doi:10.1073/pnas.0813177106
- ↑ Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D, Khalil AM, Zuk O, Amit I, Rabani M, Attardi LD, Regev A, Lander ES, Jacks T, Rinn JL. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell. 2010 Aug 6;142(3):409-19. doi: 10.1016/j.cell.2010.06.040. PMID:20673990 doi:10.1016/j.cell.2010.06.040
- ↑ Wu L, Ma CA, Zhao Y, Jain A. Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression. J Biol Chem. 2011 Jan 21;286(3):2236-44. doi: 10.1074/jbc.M110.174755. Epub 2010 , Oct 19. PMID:20959462 doi:10.1074/jbc.M110.174755
- ↑ Vaseva AV, Marchenko ND, Ji K, Tsirka SE, Holzmann S, Moll UM. p53 opens the mitochondrial permeability transition pore to trigger necrosis. Cell. 2012 Jun 22;149(7):1536-48. doi: 10.1016/j.cell.2012.05.014. PMID:22726440 doi:10.1016/j.cell.2012.05.014


text:
These are some more newcomers (scales) that I will be adding to the web store tomorrow.
I thought a couple of them might look good on a western handle.
You mean all of them might look good... damn
Thats some great looking burl Dan, Now you got my attention!!!!
Inspired by God, Forged by Fire, Tempered by Water, Grounded by Earth, Guided by the spirit.. Randy Haas
Availible Knives
That is some nice ironwood, but your wooden Rorschach test has me concerned about my mental health...
"What happened to those other underpants you had?" -- Flight of the Conchords


text:
Nissan vehicles to use common visible parts
Fiat Chrysler to abandon sub-$25,000 minivans
Kia to unveil off-roader concept at Chicago show
TRW recall shows the mess life-saving airbags have become
Toyota, Honda, Fiat Chrysler must do 'follow up' recalls of 2.12 million vehicles
Mr. Cub made history in the car business, too
Toyota thinks TRD to win younger buyers
GM's lease incentive move to captive unit surprised, angered Ally's chief
Don't get mad, get a lawyer, panelists say
One vehicle that deserved a Super Bowl ad
Volvo and the 'sweet hereafter'
Ford's new F-150 and Transit face tough scrutiny from pundits, competitors
AutoNews Now: Chevy's chance to score?
First Shift: Recall clips Honda profit
Musk at Automotive News World Congress
February 19 at 2pm ET: 5 Payment Technologies, Including Apple Pay, Affecting Your Dealership
January 20 at 2pm ET: Know The Road Ahead: Don't Guess When Investing In Dealership Markets
December 11 at 2pm ET: Building the Best: Lessons from Best Dealerships To Work For 2014
2015 Automotive News PACE Awards
2015 Automotive News Marketing Seminar - Los Angeles
2015 Automotive News Marketing Seminar - New York
1 of 5
Photos of the new model revealed at the 2013 Texas State Fair.
Your browser does not support iframes.


text:
bio | website | |
location | ||
age | 17 | |
visits | member for | 2 years, 2 months |
seen | Mar 17 '13 at 16:43 | |
stats | profile views | 0 |
I love Physics, especially creating my own theories and formulas. I'm slow, but good at Math. I hope to be a Theoretical Physicist and a Mathematician one day. It's my ultimate aim to get a PhD. and a Nobel Prize in Physics by uncovering the secrets of the Universe. Please challenge my ideas as much as you can for I believe in constructive criticism. (I hate it when righties wear their watches on their right hands. Please stop doing it if you're one of them.)


text:
tate colorblock cashmere sweater
by DEMYLEE
After graduating from Parsons School of Design, New York-based designer Demy Lee wanted to design what she appreciated most in her own closet, something she reached for just about every day...sweaters. Her line Demylee is a collection of understated basics and cashmere sweaters designed to be both current and classic. Cashmere is the foundation of her collection, to which she uses luxurious ultra fine yarns sourced from goats in Inner Mongolia. Back To Product View All From This Designer
Men's Size Chart
Product Details
Super fine, cashmere pullover in a color block knit. Slim fit with crew neckline and solid rib trim.
• 100% cashmere
• imported
• model wears size Small
• model's height: 5'9"ïÿý, bust: 32.5"ïÿý, waist: 23.5", hip: 34"ïÿý
In this look: Shoes Like Pottery Low Top Canvas Shoe