text:
Superman Homepage Ringer T-Shirt Now you can show the world that you are a fan of the No. 1 Superman site in the world! For only $17.99 you can wear this shirt with pride and help get the word out about our super community here. (More colors and designs available) US$17.99 |
Superman: Earth One Vol. 3 The follow-up to the NEW YORK TIMES #1 bestselling graphic novels SUPERMAN: EARTH ONE VOL. 1 and 2 is here! Written by J. Michael Straczynski with art by Ardian Syaf, SUPERMAN: EARTH ONE VOL. 3 follows a young Clark Kent as he continues his journey toward becoming the World's Greatest Super Hero. |
The DVD will include episodes 9-12 of the first season of the animated series: Bereft, Targets, Terrors and Home Front.
"Young Justice: Season 1, Volume 3" will be released on DVD on February 21, 2012.
Smallville News:
Back to the Latest News page.


text:
Town Square
Luck looks ahead to New York City opportunity as Heisman finalist
Original post made on Dec 7, 2010
Andrew Luck, still months away from his high school graduation, sat with two other prep quarterbacks and listened to Bill Walsh, a special adviser to the Stanford athletic department at the time. That may have been the beginning of Luck's transcendence from high school All-American to Heisman Trophy finalist.
Read the full story here Web Link posted Tuesday, December 7, 2010, 1:23 PM
Comments (1)
a resident of Stanford
on Dec 7, 2010 at 3:58 pm
Good "luck", Andrew. Just remember that if you don't win, there is always next year. Right? A Stanford education is a terrible thing to waste.
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Teavana Palo Alto closes
By Elena Kadvany | 5 comments | 2,929 views
Council Priorities 2015: Honesty, Focus, and Listening about Listening
By Douglas Moran | 10 comments | 1,707 views
Sometimes the Rules Go Out the Window
By Cheryl Bac | 5 comments | 1,627 views
What Freshmen Should be Thinking About College
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Clarifying the Process of Canonization
By Nick Taylor | 0 comments | 880 views

subset: commoncrawl


text:
Seatronics Ltd invests in iXBlue's inertial and acoustic products used for positioning in deepwater projects.
Seatronics Ltd, an Acteon company, has expanded its equipment rental pool to include more iXBlue inertial and acoustic products in response to increasing market demand for inertial navigation technology to enhance positioning for deepwater projects in West Africa and Brazil. The order, which brought the company's total 2012 expenditure with iXBlue to more than €3 million, reflects a wider shift to inertial technology as the subsea market moves away from relying on acoustic positioning solutions.
The systems covered by the latest round of investment include:
Seatronics Ltd is part of Acteon's marine electronics, instrumentation and survey business, and continuing investment in new technology is helping to maintain its position as a world leader in the rental and sale of electronic marine equipment."This investment establishes Seatronics as iXBlue's largest commercial customer and shows the faith that Seatronics and its clients have in the iXBlue product range," said Seatronics Group managing director David Currie. "We can perform system calibrations before mobilisation and integrate full inertial navigation system and multi-beam echo-sounder spreads through a high-end RTS Gen 5 fibre multiplexer solution. The combination of Seatronics' engineering support and more than 140 iXBlue assets enables us to meet customer requirements for inertial navigation system solutions."
Three large new escort tugs contracted by Norwegian operator Østensjø Rederi, will feature Wärtsilä dual-fuel (DF) engines integrated with a customized gas storage
Oman to roll out the national maritime communications network along its lengthy coastline soon, says Al-Madakhel Investment that has been tasked with design, construction
For Russian Maritime Register of Shipping (RS), 2014 marked the 101st year of its activities. The classification society said 2014 also marked a landmark year,
Greatship (India) Limited (GIL), a wholly owned subsidiary of The Great Eastern Shipping Company Limited, has signed a contract to buy a 2015-built 4000 dwt Platform Supply Vessel (PSV).
The Obama administration on Tuesday proposed allowing for the first time oil and gas exploration in a wide swath of U.S. waters off the Atlantic Coast. The
InterMoor has completed a mooring and foundation installation campaign for bpTT's Juniper gas project offshore Trinidad and Tobago, reportedly the largest foundation
Fugro N.V. announces that the Supervisory Board of Fugro nominates Mrs. P.H.M. Hofsté and Mrs. A.H. Montijn for appointment as members of the Supervisory Board
Last September the test bed in Rostock was the stage of a single lift of the RL-K 7500 subsea crane. The same crane was then loaded and shipped to the South Korean customer.


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Today, smoothies are available in many prepackaged and powdered forms. Still, they are generally prepared with juice concentrates and includes over sugar. At the time of packing, the vitamins and minerals might loss and the drink will only have empty calories and over sugar for people to drink.
If you make smoothies at home, you can ensure that right elements of healthy items have been included while making the drink, along with controlled sugar. With the help of best blender, you can emulsify different fruits, vegetables and seeds. A horsepower blender will get this job done in an effective manner.
Smoothies that are homemade would be the smart and healthy way to begin the day for kids and adults.
Besides this, you can also choose from a variety of designs and style for your HP blender to complement the kitchen. A HP blender is necessary for a kitchen to mix, chop and blend craved foods.
This product completely replaces processors and you just need to clean one appliance only. Since there are many choices of blenders available in the market, you may think that a 1 or 2 HP blender is appropriate for home use.
But, with this blender, you still need to have the processor and chop raw materials into small pieces before blending it.
So, you need to have a 3 HP blender which can save a good amount of time and produce very little waste even when the whole vegetables or fruits are used. 3 HP blenders can also crush ice without toning the blades down. Thus, buying a commercial blender for home use will offer much health, time-saving and cost effective benefits.
Why You Actually Need to Have An Omni Blender At Your Home?
If you are out in the market to buy a blender than you will surprised with the choices you are offered. There are lots of blenders' brands such as counter top blenders, crush ice blenders, immersion blenders, food processor blenders and much more. Amongst all these blenders there is one blender that has created a buzz and that is Green smoothie Omniblend blender.
This Omniblend blender is tagged as a "Green Smoothie blender" because of all right and healthy reasons. Especially; when you are dieting and looking for natural way to diet than this is the blender to go for. Using green smoothie blender means opting for healthy and simple eating habits that is perhaps most helpful in weight reducing, anti-aging, detoxifying, health enhancing and numerous other benefits.
If you are considering opting to lead a healthy life style then with just with a simple change you can do it. Buying a JTC's Omniblend blender can revolutionize your health that super charges your body with every obtainable natural resource from green vegetables and fruits. The blender very efficiently breaks open the cells of these natural produces that makes you available their natural phytochemicals and anti-oxidants which are extremely good and rejuvenating for your body and all these in one switch.
This blender comes with high powered 3HP motor with speed control and 6 cutting stainless steel blades. With 3 years of warranty period and 2 unbreakable jars it is indeed a good buy for your family that feeds them healthy.
Omniblend practices blending of fruits and vegetables at a very higher speed that makes into desirable soup or green smoothie. This may not sound most appetizing to most of you, but they are truly delicious to those who are not vegetable and fruit lovers. This nutritional green smoothie Omniblend blender has become a growing trend not amongst health conscious people, but who are seeking prevention from various diseases that develops with the age, or those who wants to improve their diet by filling it the missing gaps.
You can make your kind of healthy recipes through this Omniblend blender to avoid monotonous consumption. This green smoothie blender is often referred as the most nutritious blender available on the earth. The blender is highly sold at your nearest home appliances store or you can simply order online through any of the house-hold appliance portal.


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CES 2015: Intel introduces Compute Stick with Atom quad-core CPU
The PC-on-a-stick will come pre-loaded with Windows 8.1 for $149, or Linux for just $89, when it starts shipping in March.
The PC-on-a-stick will come pre-loaded with Windows 8.1 for $149, or Linux for just $89, when it starts shipping in March.
System monitoring can be expensive and difficult, but it doesn't have to be. Pulseway changes the enterprise monitoring and management game with its mobile management solution. Now you can receive alerts and manage your systems from anywhere on any device. Monitor and manage all of your Windows, Linux, and Mac servers and workstations with a simple app on your mobile device.
Microsoft has released a new public preview of Azure Active Directory Connect, a tool for connecting Windows Server AD to Azure AD. It will replace DirSync and the standalone Azure AD Sync tools.
The Samsung 850 EVO Series SSDs are out and they're fast, furious, and in fabulous 3D. Check out Samsung's newest SSDs by the numbers on Linux and on Windows.
Two new variants of malware targeting government and business targets have been unearthed.
Microsoft's MDOP 2014 R2 set of management and deployment tools for Windows, adds new application and user-experience virtualization features.
Microsoft is looking to the .NET Core to help bring its programming framework across different Windows flavors, as well as Linux and Mac OS X.
According to a new report from The Linux Foundation, Linux is leading Windows on both the cloud and in enterprise application deployments.
Businesses in the Asian country face unexpected performance and downtime issues with their cloud deployment, and call for more external support and tools to deal with the challenges, reveals global survey.
As Linux malware matures, Google's malware checker will give samples the same treatment as those uploaded for Windows.
The Windows, Mac and Linux versions of Flash Player all have critical security vulnerabilities patched in a new version.
Other performance monitoring and management tools tell administrators what problems occurred. Loggly claims that its tool can quickly tell them why the problems happened.
Red Hat Enterprise Linux 7 is still new, but there are even newer programming tools. Fortunately, with the latest Version of Red Hat Software Collection, programmers can keep up to speed.
Microsoft joins a push towards ARM servers that have been building up for years.
The mayor of Munich has revealed that abandoning Linux and returning to Windows, after spending years moving away from Microsoft, would cost the German city millions of euros.
New Relic, an application performance monitoring company, adds a series of tools that could expand its market beyond developers and operations execs.
Splunk says the new offerings extend its analytics platform to a broader number of users while also delivering tools to improve mobile app performance.
With the release of Lightworks version 12.0, EditShare reaches its goal of a cross-platform video NLE for Windows, Linux and now OS X. Unfortunately this is accompanied by a substantial price increase for the Pro version.
The technical preview of Windows 10 is heavy on tools for the power desktop user that businesses will want to evaluate, but the most important features will be visible later in the preview cycle.
A beta of the next version of Microsoft's Visual Studio and other new tools for Windows developers are expected to get updates in November.


text:
Sorry for the inconvenience. There may be some Navigation header breakage of "Previous:" and "Next:" links, please use the Table of Contents until things are fixed.
Difference between revisions of "IceWM/9.2"
From PC-BSD Wiki
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Drulavigne (Talk | contribs) |
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− | {{NavHeader|back=Enlightenment|forward= | + | {{NavHeader|back=Enlightenment|forward=ScrotWM}} |
[http://www.icewm.org/ IceWM] is a light-weight window manager. | [http://www.icewm.org/ IceWM] is a light-weight window manager. | ||
Revision as of 12:05, 27 July 2011
(Sorry for the inconvenience)
IceWM is a light-weight window manager.
Figure 5.7a shows a screenshot of IceWM running on PC-BSD. In this example, the user has launched the Application menu by clicking on the IceWM button in the lower left corner. This menu can also be launched by right-clicking anywhere on the desktop.
Figure 5.7a: IceWM on PC-BSD


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Welcome to Flickr Hive Mind, almost certainly the best photo search engine on the web. Returning logged in users may need to re-authenticate for FHM to work properly (go to preferences, log out, log in)
Dropbox storage - get 20 GB of Cloud Storage for free.
50 hairy arms 30 woman 29 women 28 girl 23 hair 18 arm 4 man legs chest men muscle 3 paulo moreno carvalho torax boy nipples black beard furry peito vieira bear de famous arpit braço stubble mamilos diego torso muscles nipple sao january sampa bracelet fauna zoo dinossauro 2010 selfportrait pirates san pablo dino pimata daddy morcego cascavel amazon brazil fish crocodilo tattoo aquario cobra ginger jiboia lady crock girls animals delll pinguin deo redheaded aquarium dinossaur jacare pirata flora amazonas animais face deu masculine tematico hands serpente sucuri brasil tamandua long peixe guy paulblackely fat butt santos pose chino talking fit male masayas vision:face=099 paulista microscope mirror december ugly portraiture powertool compound jardin vision:people=099 52260mm 2006 sexy biceps screws red privacy wristwatch me spiritlevel wymm nebulous powertools framing tent pregnant gay cell distort familia back diptych phone eye papa swimwear stretch sideburns okeeheeleepark mustache homosexual sunglasses sunshades diy chang tshirt yucky macro balding ofme swirl shirtless espelho wedding joshcolwell famili work margaretatwood chesthair masaya customerservice hoodie diptyque religión cloud whiteman flower machado drill cellphone embarazada hyland lines gym estadio bald pyrex lounge sketchbook boda pic chubby hand willyoumarryme cold hunk spider fly bride cel mysterious unselfconscious fadedcolours vneck bignose dorothy vindell foto outofbed funnel vision:outdoor=0893 menatwork frames spooky novia novio color originals 2009 positivespin buffed hijo sarah edible oz flexing head circle smile pacaembu science sketch arthropod leather zines belly scary happy zine washedout tool 2013 carnaval vision:text=0501 tools chinos level photocopy beach frame feliz shorts sugarcookies fadedcolors domingo vision:groupshot=099 fade couple matrimonio florida academia lasagna recording uncensored soul mama facets workout outside s0ulsurfing vision:outdoor=0747 daisy portrait blue experimental mail picture wizard working play upclose groome vision:outdoor=0719
Pairs: 44 arms,hairy 29 hairy,women arms,women woman,women hairy,woman arms,woman 28 arms,girl girl,hairy 27 girl,woman girl,women 22 hair,hairy
Users: JenniferChristie 29 diegovieiradecarvalho 3 rrttrrtt555 LittleOtter jorgemejia melissamurphy1989 I Love Elizabeth Warren - LarryJay99 sandy_kreps missgreenbean jdevious Nathan Wade Carter markusshoppen dimitri_ca jamesofoakland s0ulsurfing nettsu cheshirecat666-the fur files
Flickr Hive Mind is a search engine as well as an experiment in the power of Folksonomies. All thumbnail images come directly from Flickr, none are stored on Flickr Hive Mind. These photos are bound by the copyright and license of their owners, the thumbnail links take to you to the photos (as well as their copyright and license details) within Flickr. Because some other search engines (Google, etc.) index parts of Flickr Hive Mind, you may have been led here from one of them. Welcome to Flickr Hive Mind, almost certainly the best search engine for photography on the web. If you are a Flickr user and use Flickr Stats you may have seen people being led to your photos via Flickr Hive Mind (as a Referrer). Flickr requires that I inform you that Flickr Hive Mind uses the Flickr API, but is neither endorsed nor certified by them. There are literally hundreds of other web tools built around the Flickr API, see Flickr Bits for a bunch of examples. If you are unhappy with your photos' presence on this site, you can (a) make your photos private for yourself, friends, and family. These settings will be instantly honored by Flickr Hive Mind and all other API-driven applications. (b) Hide your photos globally from text and tag searches on 3rd party sites that use the Flickr API, via your preference settings on Flickr. See the privacy tab at: http://flickr.com/account/. To also remove yourself from searches for specific user names, you will need to set your Flickr profile to be hidden from searches. Flickr has finally created a single page with all these settings, this is much easier to do now and is the preferred method - it will shut down all API driven sites. (c) Finally, you can Banish Yourself From Flickr Hive Mind. To banish yourself from Flickr Hive Mind, you must first authenticate to Flickr, which lets Flickr Hive Mind identify who you are. Once logged in, come back to this area and there will be a link to banish you. If there are any problems email me at nosflickrhivemind ... at ... fiveprime ... dot ... org. (a few people with weird characters in their user names may have had problems)Log In To Flickr Now
Flickr Hive Mind is a data mining tool for the Flickr photography database, allowing search by: tags(keywords); Flickr photography groups; Flickr users, their contacts, and favorites; free text; the Flickr Explore algorithm for interestingness. Flickr Hive Mind can also be an effective tool to identify photography with licenses that allow non-commercial (and sometimes) commercial use. Written by: Nathan Siemers. Inspired by (and thanks to) Flickr Leech. Dedicated to Anna and her Flickritis. If you find your login does not work, perhaps your browser has disabled the cookies that I use to track your session. Try telling your browser to accept them. Flickr Hive Mind stores no personal information nor photos, but some general time and IP address information ends up in my apache server logs. For additional details see the privacy policy. Any revenue generated through advertisement on this site is used only to cover the cost of keeping the site online, beyond that Fiveprime donates to charitable organizations (also, there are no ads on User pages). Flickr Hive Mind is currently consuming about 13.6 terabytes of network bandwidth per year (not including the photos themselves)!
Fiveprime.org supports The Mountain Institute - Sustaining mountain people, cultures and environments through education, conservancy, and sustainable development.


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Baked ricotta with pear and walnut salad
Jill Dupleix transforms creamy fresh ricotta into a beautiful dinner by baking it and serving with a crunchy Italian-style salad.
To Prep |
To Cook |
AVG RATING (0 Members) |
recipe To my
- Ingredients
- Nutrition
Energy 1619kJ |
Fat saturated 11.80g |
Fat Total 27.10g |
Carbohydrate sugars 9.70g |
Carbohydrate Total 18.90g |
Dietary Fibre 2.70g |
Protein 15.00g |
Cholesterol 36.00mg |
Sodium 392.00mg |
All nutrition values are per serve.
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Pronunciation: /ˈhəʊpləsnəs; ˈhəʊplɪsnɪs/
Translation of hopelessness in Spanish:
uncountable/no numerable- 1.1 (of situation) lo desesperado 1.2 (despair) desesperanza (feminine)
Definition of hopelessness in:
- British & World English dictionary
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Cultural fact of the day
An estanco is an establishment selling tobacco, stamps, bus and subway passes and other products whose sale is restricted. Cigarettes etc are sold in bars and cafés but at higher prices. Estancos also sell stationery and sometimes newspapers.


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Published June 29, 2012
- Music by: Mountaineering Club
- Read the article on Grapevine.is Here
Published June 29, 2012
Like most decent Reykjavikings, Grapevine's friend Kormákur Arthursson hung out in 101 Reykjavík on December 23rd. His trusty smartphone in
We caught up with Krummi Björgvinsson and had a chat about his new project, Döpur. Krummi is notorious for his
Mathcore-hardcore band In The Company Of Men just released their first video! Ever! The video to song "Lost In Black"
We sat down with the poet-punk trio of Kælan mikla after their gig at Dillon and talked about punk, poetry
We met up with frontman Kalli of hardcore powerhouse band Muck and talked about singing in English, graffiti, and shiny
We caught up with duo Logi and Karen of Highlands (now Young Karin) after their very first show at Harlem.


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Our staff will deliver extraordinary guest service.
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Read a book; work on your computer; or just people watch in our cozy lobby.
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Enjoy more room in our guest rooms with two queen beds.
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Our King Studio features a separate living area.
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The Corner Suite features a 47-inch HDTV and has DirecTV programming.
Suite Amenities
Our suites feature well-lit desks with comfortable seating. All of our rooms feature over 100 channels of HD programming.
Suite Bathroom
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Our business center has complimentary Wi-Fi, printing, and faxing.
The Corner Market
Snacks, beverages and sundries are available 24 hours per day in our Corner Market.
Breakfast Area
Enjoy our complimentary hot breakfast daily.
Dining Area
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Find relaxation in our large refreshing pool.
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Our fitness center is open 24 hours and features free weights as well as cardio equipment.
Peachtree Meeting Space
Our meeting space can accommodate many different setups and sizes. We have the technology to make your meetings easy and affective.


text:
- Actors: John Cusack, Chiwetel Ejiofor, Danny Glover, Woody Harrelson, Tom McCarthy
- Directors: Roland Emmerich
- Format: Multiple Formats, AC-3, Color, Dolby, Dubbed, NTSC, Subtitled, Widescreen
- Language: English, French
- Subtitles: English, French
- Dubbed: French
- Region: Region 1 encoding (US and Canada only)
PLEASE NOTE: Some Region 1 DVDs may contain Regional Coding Enhancement (RCE). Some, but not all, of our international customers have had problems playing these enhanced discs on what are called "region-free" DVD players. For more information on RCE, click . - Aspect Ratio: 2.40:1
- Number of discs: 1
- Rated: PG-13 (Parental Guidance Suggested)
- Studio: Sony Pictures
- DVD Release Date: March 2, 2010
- Run Time: 158 minutes
- Average Customer Review: 3.4 out of 5 stars See all reviews (957 customer reviews)
- Amazon Best Sellers Rank: #8,323 in Movies & TV (See Top 100 in Movies & TV)
- Learn more about "2012" on IMDb
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text:
Definition of conflama
- When situations include conflict AND drama.
"Our different perspectives on this issue created a lot of conflama for all involved."Last edited on Feb 19 2010. Submitted by Steve from Boulder, CO, USA on Feb 19 2010.
+ | Add a definition for this slang term |
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None. How about some random words?
Definitions include: to stop talking. | |
Definitions include: a female travel-companion. | |
Definitions include: This term means "Your fly (zipper) is open". | |
Definitions include: under 18, jail bait. | |
Definitions include: to imitate competitors. | |
Definitions include: Short for American. | |
Definitions include: semen. | |
Definitions include: a remark on the repetitive, boring nature of life. | |
Definitions include: one who behaves as a goddess or queen. | |
Definitions include: in collusion with. |
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text:
Burning Man Video Acculturation Trailer
4 years ago
Super 8 Female Performance Artists: "Lisa Bufano"
5 years ago
Female Performance Artists: "Valerie Geffner"
Here are all of the videos that rosalie has uploaded to Vimeo. Appearances are videos that rosalie has been credited in by others.
More stuff from rosalie
3 Videos
2 Channels
6 Groups
1 Album


text:
Book your room at Hotel Zdraviliški Dvor
Economy Double Room
Max Occupancy: 2 guests (up to 1 child, 1 infant)Classic Twin Room
Max Occupancy: 2 guests (up to 1 child, 1 infant)Classic Single Room
Max Occupancy: 1 guestClassic Double Room Single Use
Max Occupancy: 1 guestRiverfront hotel with 2 restaurants and restaurant
Situated in the historical district, this spa hotel is within 6 mi (10 km) of Church of St. Martin, Laskem Park, and Tabor Castle. Celje Castle and Museum of Recent History are also within 12 mi (20 km).
Nearest Transport Options
Nearest Airports
Hotel Features
2 restaurants, a restaurant, and an indoor pool are available at this hotel. Free WiFi in public areas and train station pick-up are also provided. Other amenities include an outdoor pool, a fitness center, and a bar/lounge.
Room Amenities
All 76 rooms provide free wired Internet, room service, and satellite TV. Hair dryers, safes, and showers are among the other amenities that guests will find.
Information missing or incorrect? Tell us!


text:
A sundress made from light silk habutai for this hot summer days! The dress is based on Burda Style patterns # 111 from the March issue. I drafted a princess seam back and made a shorter skirt.
For more details I invite you to read my blog
Jun 23, 2013, 07.27 PMby Monty Howe
I like the style and the print, kinda hippy.
Jun 23, 2013, 07.00 PMby loves2sew555
I love the pattern on the fabric; it is so pretty :) perfect summer dress
Jun 23, 2013, 06.19 PMby Mary Athey
gorgeous dress, the fabrics lovely and its a great shape on you x
We have just extended registration to accommodate a few more students
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Many of the world's leading companies and organizations use Mynewsdesk to publish their news. We can help you find the stories most relevant to you. Receive the news you want directly in your inbox, on your own terms.
Press Release • 27 Jan 09:22 GMT
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Researchers at Chalmers University of Technology have discovered that the insulation plastic used in high-voltage cables can wi... Read more
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Research published by ISACA has shown that close to half (46%) of respondents to a global survey of IT professionals expect the... Read more
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Phoenix Contact has extended its FL COM-Server serial device server product range with two special versions with an extended te... Read more
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International Railway Journal and IRITS Events Ltd are proud to announce the participation of Banedanmark, the publicly owned ... Read more
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The Republic of the Union of Myanmar has engaged the services of ÅF as part of a project implementation consultancy assignment ... Read more
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The FDA's Breakthrough Therapy Designation is big news. As of December 29, 2014, the US Agency has given 16 approvals to drugs ... Read more
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I'll feel more confident about the economy when this ratio begins growing robustly instead of bouncing along the bottom of the valley like it's doing now.
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Do you know how rich the family of founder Sam Walton is or where Walmart stands as a user of solar power? Read on
Some of these careers are not all they're cracked up to be, while others have serious potential


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Publications (31)173.15 Total impact
Article: Genetic Spectrum and Clinical Correlates of Somatic Mutations in Aldosterone-Producing Adenoma.
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ABSTRACT: Primary aldosteronism is the most common form of secondary hypertension. Somatic mutations in KCNJ5, ATP1A1, ATP2B3, and CACNA1D have been described in aldosterone-producing adenomas (APAs). Our aim was to investigate the prevalence of somatic mutations in these genes in unselected patients with APA (n=474), collected through the European Network for the Study of Adrenal Tumors. Correlations with clinical and biochemical parameters were first analyzed in a subset of 199 patients from a single center and then replicated in 2 additional centers. Somatic heterozygous KCNJ5 mutations were present in 38% (180/474) of APAs, whereas ATP1A1 mutations were found in 5.3% (25/474) and ATP2B3 mutations in 1.7% (8/474) of APAs. Previously reported somatic CACNA1D mutations as well as 10 novel CACNA1D mutations were identified in 44 of 474 (9.3%) APAs. There was no difference in the cellular composition of APAs or in CYP11B2, CYP11B1, KCNJ5, CACNA1D, or ATP1A1 gene expression in APAs across genotypes. Patients with KCNJ5 mutations were more frequently female, diagnosed younger, and with higher minimal plasma potassium concentrations compared with CACNA1D mutation carriers or noncarriers. CACNA1D mutations were associated with smaller adenomas. These associations were largely dependent on the population structure of the different centers. In conclusion, recurrent somatic mutations were identified in 54% of APAs. Young women with APAs are more likely to be KCNJ5 mutation carriers; identification of specific characteristics or surrogate biomarkers of mutation status may lead to targeted treatment options.Hypertension 05/2014; · 7.63 Impact Factor -
Article: KCNJ5 mutations in aldosterone producing adenoma and relationship with adrenal cortex remodeling.
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ABSTRACT: Somatic mutations of KCNJ5, coding for the potassium channel GIRK4, have recently been implicated in the formation of aldosterone producing adenoma (APA). While a causal link between KCNJ5 mutations, membrane depolarization and aldosterone production has been established, the precise mechanism by which these mutations promote cell proliferation and APA formation remains unclear. The aim of our study was to correlate KCNJ5 mutation status with morphological and functional characteristics of the adrenal cortex adjacent to APA. While GIRK4 was expressed in APA and in the zona glomerulosa of the adjacent cortex, significantly lower levels were detected in APA harboring a KCNJ5 mutation. There was no correlation between KCNJ5 mutation status and the morphological measures of adrenal cortex remodeling, including nodulation, vascularization and expression of CYP11B2. The cell composition of APA was not significantly different between groups. These results indicate that KCNJ5 mutations are not correlated with adrenal cortex remodeling in APA.Molecular and Cellular Endocrinology 01/2013; · 4.24 Impact Factor - Annales d Endocrinologie 09/2012; 73(4):265. · 0.66 Impact Factor
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ABSTRACT: Aldosterone producing adenoma (APA) is the most common form of surgically curable hypertension. To further understand mechanisms involved in APA formation, we investigated the expression of molecules linked to adrenal stem/precursor cells [β-catenin, Sonic hedgehog (Shh), CD56], and nuclear receptors that play key roles in adrenocortical development and function steroidogenic factor 1, dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1) in six control adrenal glands and 14 adrenals with APA and compared their expression with that of specific markers of zona glomerulosa (ZG) [CYP11B2, Disabled 2 (Dab2)]. Both Dab2 and CD56 were expressed in ZG. Although Dab2 associates uniquely with differentiated ZG cells and its expression is lost when cells transdifferentiate to zona fasciculata (ZF) cells, CD56 was also expressed in ZF and in aldosterone-producing cell clusters, confirming that these structures possess an intermediate phenotype between ZG and ZF cells. Shh was barely detectable in cells located to the outer part of the ZG in the control adrenal; in contrast, its expression was detected in the entire APA and was dramatically increased in the hyperplastic peritumoral ZG. Transcriptome profiling revealed differential expression of components of Shh signaling pathway in a subgroup of APA. Similarly, Wnt/β-catenin signaling was activated in the majority of APA as well as in the entire peritumoral adrenal cortex; however, no mutation was identified in the CTNNB1 gene that could account for β-catenin activation. Our data suggest that both APA and adjacent ZG present characteristics of stem/precursor cells; the reexpression of genes involved in fetal adrenal development could underlie excessive ZG cell proliferation and APA formation.Endocrinology 12/2011; 152(12):4753-63. · 4.72 Impact Factor - La Revue de Médecine Interne 12/2011; 32:S277. · 1.32 Impact Factor
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ABSTRACT: The prognosis of patients with colorectal cancer has sometimes proved uncertain; thus, the prognostic significance of immune criteria was compared with that of the tumor extension criteria using the American Joint Committee on Cancer/International Union Against Cancer-TNM (AJCC/UICC-TNM) staging system. We studied the intratumoral immune infiltrates in the center of the tumor and in the invasive margin of 599 specimens of stage I to IV colorectal cancers from two independent cohorts. We analyzed these findings in relation to the degree of tumor extension and to the frequency of recurrence. Growth of the primary tumor and metastatic spread were associated with decreased intratumoral immune T-cell densities. Sixty percent of patients with high densities of CD8(+) cytotoxic T-lymphocyte infiltrate presented with stage Tis/T1 tumor, whereas no patients with low densities presented with such early-stage tumor. In patients who did not relapse, the density of CD8 infiltrates was inversely correlated with T stage. In contrast, in patients whose tumor recurred, the number of CD8 cells was low regardless of the T stage of the tumor. Univariate analysis showed that the immune score was significantly associated with differences in disease-free, disease-specific, and overall survival (hazard ratio [HR], 0.64, 0.60, and 0.70, respectively; P < .005). Time-dependent receiver operating characteristic curve analysis illustrated the predictive accuracy of the immune parameters (c-index = 65.3%, time-dependent c-index [Cτ] = 66.5%). A final stepwise model for Cox multivariate analysis supports the advantage of the immune score (HR, 0.64; P < .001; Cτ = 67.9%) compared with histopathologic features in predicting recurrence as well as survival. Assessment of CD8(+) cytotoxic T lymphocytes in combined tumor regions provides an indicator of tumor recurrence beyond that predicted by AJCC/UICC-TNM staging.Journal of Clinical Oncology 02/2011; 29(6):610-8. · 17.88 Impact Factor -
Article: Adrenal cortex remodeling and functional zona glomerulosa hyperplasia in primary aldosteronism.
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ABSTRACT: Primary aldosteronism is the most common form of secondary hypertension with hypokalemia and suppressed renin-angiotensin system caused by autonomous aldosterone production. Our aim was to compare zona glomerulosa (ZG) structure and function between control adrenals and the peritumoral tissue from patients operated on for aldosterone-producing adenoma. ZG morphology and CYP11B1, CYP11B2, and disabled 2 expression were studied in 15 control adrenals and 25 adrenals with aldosterone-producing adenoma. A transcriptome analysis was done using publicly available data sets. In control adrenals, ZG was discontinuous, and CYP11B2 expression was focal or partly continuous and localized to 3 structures, foci, megafoci, and aldosterone-producing cell clusters. CYP11B2 expression was restricted to a limited number of ZG cells expressing Dab2 but not CYP11B1; aldosterone-producing cell clusters were composed of cells with an intermediate phenotype expressing CYP11B2 but not disabled 2 or CYP11B1. In peritumoral tissue, large remodeling of the adrenal cortex was observed with increased nodulation and decreased vascularization that were not correlated with CYP11B2 expression. In 17 out of 25 adrenals, hyperplasia of adjacent ZG was observed with persistent expression of CYP11B2 that was extended to the entire ZG. In all of the adrenals from patients with aldosterone-producing adenoma, CYP11B2 expression was present in foci, megafoci, and aldosterone-producing cell clusters. Transcriptome profiling indicates a close relationship between peritumoral and control adrenal cortex. In conclusion, adrenal cortex remodeling, reduced vascularization, and ZG hyperplasia are major features of adrenals with aldosterone-producing adenoma. Transcriptional phenotyping is not in favor of this being an intermediate step toward the formation of aldosterone-producing adenoma.Hypertension 10/2010; 56(5):885-92. · 7.63 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: In adrenocortical tumors (ACT), Wnt/β-catenin pathway activation can be explained by β-catenin somatic mutations only in a subset of tumors. ACT is observed in patients with familial adenomatous polyposis (FAP) with germline APC mutations, as well as in patients with Beckwith-Wiedemann syndrome with Wilms' tumors reported to have WTX somatic mutations. Both APC and WTX are involved in Wnt/β-catenin pathway regulation and may play a role in ACT tumorigenesis. The aim of this study was to report if APC and WTX may be associated with FAP-associated and sporadic ACT. ACTs from patients with FAP and sporadic adrenocortical carcinomas (ACC) with abnormal β-catenin localization on immunohistochemistry but no somatic β-catenin mutations were studied. APC was analyzed by denaturing high-performance liquid chromatography followed by direct sequencing and by multiplex ligation-dependent probe amplification when allelic loss was suspected. WTX was studied by direct sequencing. Four ACTs were observed in three patients with FAP and were ACC, adrenocortical adenoma, and bilateral macronodular adrenocortical hyperplasia, all with abnormal β-catenin localization. Biallelic inactivation of APC was strongly suggested by the simultaneous existence of somatic and germline alterations in all ACTs. In the 20 sporadic ACCs, a silent heterozygous somatic mutation as well as a rare heterozygous polymorphism in APC was found. No WTX mutations were observed. ACT should be considered a FAP tumor. Biallelic APC inactivation mediates activation of the Wnt/β-catenin pathway in the ACTs of patients with FAP. In contrast, APC and WTX genetic alterations do not play a significant role in sporadic ACC.Clinical Cancer Research 10/2010; 16(21):5133-41. · 8.19 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: KRAS mutations are a strong predictive marker of resistance to anti-epidermal growth factor receptor (EGFR) antibodies in advanced colorectal cancer (CRC) but only a subset of wild-type (WT) KRAS patients are responders, suggesting the existence of additional markers of resistance to this treatment. The activation of EGFR downstream signaling pathways may be one of these ones. In a series of 42 patients with advanced CRC treated with cetuximab/panitumumab, for whom KRAS status was previously determined, we retrospectively analyzed the intratumor expression of EGFR downstream signaling phosphoproteins of the RAS/MAPK and PI3K/AKT pathways (pERK1/2, pMEK1, pAKT, pP70S6K and pGSK3beta) using Bio-Plex phosphoprotein array. Association with tumor response, progression-free survival (PFS) and overall survival (OS) was assessed. The expression of all the phosphoproteins was higher in KRAS mutated tumors than in WT tumors. The expression of pP70S6K was lower in responders than in nonresponder patients. In univariate analysis, patients with high pMEK1 or pP70S6K expression had a shorter PFS than those with low expression. Patients with high pP70S6K expression also had a shorter OS. In multivariate analysis, PFS was shorter for patients with high pMEK1 or pP70S6K expression, independently of KRAS status, as OS for patients with high pP70S6K expression. Therefore, WT KRAS patients with high pP70S6K expression had a shorter survival than those with low expression. Our results suggest the importance of EGFR downstream signaling phosphoproteins expression in addition to KRAS status to define the subgroup of patients who will not benefit from anti-EGFR therapy.International Journal of Cancer 09/2010; 127(6):1321-31. · 6.20 Impact Factor - Journal of Hypertension 01/2010; 28. · 4.22 Impact Factor
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ABSTRACT: Phaeochromocytomas and paragangliomas are neuro-endocrine tumours that occur sporadically and in several hereditary tumour syndromes, including the phaeochromocytoma-paraganglioma syndrome. This syndrome is caused by germline mutations in succinate dehydrogenase B (SDHB), C (SDHC), or D (SDHD) genes. Clinically, the phaeochromocytoma-paraganglioma syndrome is often unrecognised, although 10-30% of apparently sporadic phaeochromocytomas and paragangliomas harbour germline SDH-gene mutations. Despite these figures, the screening of phaeochromocytomas and paragangliomas for mutations in the SDH genes to detect phaeochromocytoma-paraganglioma syndrome is rarely done because of time and financial constraints. We investigated whether SDHB immunohistochemistry could effectively discriminate between SDH-related and non-SDH-related phaeochromocytomas and paragangliomas in large retrospective and prospective tumour series. Immunohistochemistry for SDHB was done on 220 tumours. Two retrospective series of 175 phaeochromocytomas and paragangliomas with known germline mutation status for phaeochromocytoma-susceptibility or paraganglioma-susceptibility genes were investigated. Additionally, a prospective series of 45 phaeochromocytomas and paragangliomas was investigated for SDHB immunostaining followed by SDHB, SDHC, and SDHD mutation testing. SDHB protein expression was absent in all 102 phaeochromocytomas and paragangliomas with an SDHB, SDHC, or SDHD mutation, but was present in all 65 paraganglionic tumours related to multiple endocrine neoplasia type 2, von Hippel-Lindau disease, and neurofibromatosis type 1. 47 (89%) of the 53 phaeochromocytomas and paragangliomas with no syndromic germline mutation showed SDHB expression. The sensitivity and specificity of the SDHB immunohistochemistry to detect the presence of an SDH mutation in the prospective series were 100% (95% CI 87-100) and 84% (60-97), respectively. Phaeochromocytoma-paraganglioma syndrome can be diagnosed reliably by an immunohistochemical procedure. SDHB, SDHC, and SDHD germline mutation testing is indicated only in patients with SDHB-negative tumours. SDHB immunohistochemistry on phaeochromocytomas and paragangliomas could improve the diagnosis of phaeochromocytoma-paraganglioma syndrome. The Netherlands Organisation for Scientific Research, Dutch Cancer Society, Vanderes Foundation, Association pour la Recherche contre le Cancer, Institut National de la Santé et de la Recherche Médicale, and a PHRC grant COMETE 3 for the COMETE network.The Lancet Oncology 09/2009; 10(8):764-71. · 25.12 Impact Factor - The American Journal of Gastroenterology 05/2009; 104(4):1069. · 9.21 Impact Factor
Article: [Management of small bowel polyps].
Gastroentérologie Clinique et Biologique 04/2009; 33(4):247-52. · 1.14 Impact Factor - Gastroentérologie Clinique et Biologique 04/2009; 33(4):247-252. · 1.14 Impact Factor
- Gastroentérologie Clinique et Biologique 04/2009; 33(3):186. · 1.14 Impact Factor
- Gastroentérologie Clinique et Biologique 03/2009; 33(3):186-186. · 1.14 Impact Factor
- Gastroentérologie Clinique et Biologique 03/2009; 33(3):225-6. · 1.14 Impact Factor
- Annales d Otolaryngologie et de Chirurgie Cervico-Faciale 12/2008; 125(6):331-40.
- Annales d Otolaryngologie et de Chirurgie Cervico-Faciale 12/2008; 125(6):331-340.
- Gastroentérologie Clinique et Biologique 08/2008; 32(8):782-784. · 1.14 Impact Factor
Publication Stats
1k | Citations | |
173.15 | Total Impact Points | |
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Université René Descartes - Paris 5
Lutetia Parisorum, Île-de-France, France
French Institute of Health and Medical Research
Lutetia Parisorum, Île-de-France, France
Hôpital Européen Georges-Pompidou (Hôpitaux Universitaires Paris-Ouest)
- Service d'Anatomie-Pathologie
Lutetia Parisorum, Île-de-France, France


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Jovan Belcher's Secret Girlfriend Should Have Acted on "Would Shoot" Text Message
The murder-suicide story involving Kansas City Chiefs linebacker Jovan Belcher keeps getting worse and worse. A newly-surfaced police report states Belcher texted his "secret girlfriend" several weeks before he killed Kasandra Perkins, the mother of his three-month-old daughter, saying he "would "shoot" her "if she didn't leave him alone."
Naturally, the still undisclosed secret girlfriend said she thought Belcher was joking. Earlier reports state Belcher and Perkins had an argument the night before he murdered her and then took his own life at the Chiefs' team facility in front of head coach Romeo Crenell. Needless to say, things are starting to add up.
Of course, nothing is any excuse to take someone else's life or one's own. Some feel sympathy for both Perkins and Belcher while others perceive the now former Chiefs linebacker a murderer, which technically, he is.
Some moronic talking heads, namely NBC's Bob Costas, have used this tragic story as a platform for stances against things like gun control and such individuals should be stripped of their titles. Regardless of your opinion of Belcher, a murder, his family is going through something right now that no one should ever experience. If a loved one of yours committed suicide and/or took another person's life, would you want some idiot like Costas discussing a political issue like this while your loved one's death was the headline? Of course not! And you'd probably have some pretty ill feelings toward that talking head, and rightfully so!
What should be taken away from this new information regarding the case is nothing should be assumed anymore. The teachers and students at Sandy Hook Elementary School in Newtown, Connecticut assumed no insane 20-year-old would come into their school and shoot them just like Crenell assumed none of his players would murder anyone, much less themselves, in front of him at the team's facility.
The NFL seems to have been in hot water lately regarding player safety, but this is the other part of. That is the only other spin to this story you should even consider, Mr. Costas.
Jeric Griffin is the Director of Content for RantSports.com. Follow him on Twitter @JericGriffin, "Like" him on Facebook or add him to your network on Google
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Hedgehug: A Sharp Lesson in Love (Hardcover)
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Love is patient, and love is kind,
but for Hedgehug love is prickly, too.
Join this lonely hedgehog as he searches
for someone to accept his heart .
About the Author
Dan Pinto lives in Brooklyn. He likes to draw things. He once drew a bunch of drawings that eventually became a film called Hedgehug. The book youre now holding is based on that film. Its Dans first book. He hopes you like it.
Benn Sutton is a writer living in Sydney, Australia. He doesnt know much about love, but he sure knows what its like to be a prickly character.


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Latest Articles
Premier League: Nicolas Anelka free to resume playing career in England
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Nicolas Anelka is free to resume his career in England after completing an education course following his quenelle gesture.
Transfer news: James Dayton joins St Mirren from Oldham on loan
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St Mirren have signed winger James Dayton from Oldham on loan until the end of the season.
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QPR midfielder Joey Barton is prepared to make a significant financial "sacrifice" to be able to play for Everton, according to his agent Willie McKay.
The 30-year-old spent last season on loan at Marseille and appears to have no future at Loftus Road, especially on reported wages of £70,000 a week, after their relegation to the Championship.
But his salary has put off the French club from making a move to sign him permanently and McKay is exploring other options in an attempt to find a new club.
Huyton-born Barton supported the Toffees as a boy and has this morning tweeted "Once a blue.." and his agent admits they have approached new manager Roberto Martinez about an opportunity.
"Obviously his package with QPR is pretty big for Marseille's terms really," McKay told talkSPORT.
"Joey said there was only one club he would make a sacrifice for and it would be Everton and I made that call to Martinez.
"That is the club he loves. I have approached them and said Joey would love to have Everton on his CV.
"Fair play to him he said he would lose money to go to Everton - and not many professionals would do that."
McKay claims Martinez, who is in the market for a central midfielder, is an admirer of Barton.
"Roberto Martinez said he likes him as a player and he also spoke to (Martinez's assistant Graeme Jones, who loves him as a player," he added.
"Anything can happen in football. It could happen."
Everton will not comment on speculation about players at other clubs.
However, Press Association Sport understands there is little likelihood of Barton securing a move to Goodison Park.
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Written by KRISTEN GELINEAU, Associated Press
SYDNEY (AP) — Amid a barrage of gunfire, police stormed a cafe in the heart of Sydney early Tuesday to end a 16-hour hostage siege by an Iranian-born gunman. Police said three people were killed — the gunman and two of the hostages — and four others were wounded.
Written by PAT EATON-ROBB, Associated Press DAVE COLLINS, Associated Press
HARTFORD, Conn. (AP) — The families of nine people killed in the Newtown school massacre filed a lawsuit against the maker and sellers of the Bushmaster AR-15 rifle used in the shooting, saying the gun should not have been sold for civilian use because of its overwhelming firepower.
Written by RICARDO ALONSO-ZALDIVAR, Associated Press
WASHINGTON (AP) — President Barack Obama's push to cover America's uninsured faces another big test Monday.
Written by THE ASSOCIATED PRESS
WASHINGTON (AP) — The Supreme Court is refusing to allow Arizona to enforce stringent restrictions on medical abortions while a challenge to those rules plays out in lower courts.
Written by MARILYNN MARCHIONE, AP Chief Medical Writer
Scientists often test drugs in mice. Now some cancer patients are doing the same — with the hope of curing their own disease.
Written by DAN PERRY, Associated Press JOSEF FEDERMAN, Associated Press
JERUSALEM (AP) — The population of Jewish settlers in the occupied West Bank has surged during Prime Minister Benjamin Netanyahu's years in office, growing at more than twice the pace of Israel's overall population, according to newly obtained official figures.
Written by STEVEN DUBOIS, Associated Press
PORTLAND, Ore. (AP) — A suspect in a shooting that wounded three students outside an alternative high school was arrested early Saturday in what appears to be a gang-related attack, Portland police said.
Written by MATTHEW BARAKAT
WASHINGTON (AP) — Protesters plan to converge on the nation's capital Saturday to help bring attention to the deaths of unarmed black men at the hands of police and call for legislative action.


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Welcome to Chair City Community Church!
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Life's most meaningful elements, peace with God, loving others, and finding purpose seem impossible to reach in our lives. The Good News is Jesus has enabled us to have all and it's part of His "Mission Possible" for you and me. Join us for this 3 week series as we discover "Mission Possible"!
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Break the Limits!
You are trapped in a room and the only thing you can do is think.
4.15 / 5.00 38,411 ViewsCap'n Marcela
Can you help Cap'n Marcela save her village from Evil Puffy shirt Morgan?
3.93 / 5.00 6,257 Views* For all of the frustrated ones: there's a video walkthrough thread at We Create Stuff > Portal: TFV's forum, and some community help. Good luck :)
We started working on this project a couple of months ago, and now, it is finally done. Lately we've been working on this project none stop, acknowledging if we release it after the real Portal - we fail, and our test will be terminated ( ;). So yes, the last piece of code of this game was programed just a couple of minutes ago. Don't worry - those minutes were on bugs!
Portal: The Flash Version includes over 40 challenging, portals thinking levels, which features almost every feature the real game does, in 2d - energy balls, cubes, turrets and even the famous crusher from the trailer. The game also includes a console to mess around with after finishing the game, or just being frustrated by thinking with portals (Commands are posted in our forums)
Left mouse button - launch a portal.
A W D - movement
Q - launch a blue portal.
E - launch a yellow portal.
R - Close both portals.
F - pick up an object.
~ - open up console (enable through the options)
O - quick quality adjust.
Esc/P - pause game.
Version history:
The game really is heavy on levels 30 and up. We did our best to optimize it, but if you still have a low frame rate simply change your quality and effect settings.
If you find any bugs, please report.
console commands
Level skip - nextlevel
previous level - prevlevel
Set gravity - gravity [0][number]
Suicide - kill
Go through walls with [Cursor keys] - noclip
View game information - info
Toggle sound - sound, sounds, or autoquality
Hold [Space] to open a portal - space, aim, or detectshot
Set quality level - quality [0-3]
Set effects level - effects [0-2]
View frame rate and level number - showfps
Toggle God mode - god
Toggle Portal Proof mode - portalproof or antiportal
Toggle dancing - dance or /dance
Toggle crosshair - crosshair
toggle Playercam - dynamiccam or dynamicam
Stop all sounds currently running - stopallsounds or stopsounds
Toggle map box - showmapbox
Toggle display of Portal box - showportalbox
Toggle display of Portal hit box - showportalhitbox
Toggle display of Portal mask - showportalmask
Toggle step visibility - showsteps or showstep
Toggle shot visibility - showshot or showshots
Spawn Box - createbox
Remove Box - removebox
Spawn Cam - createcam
Remove Cam - removecam
Spawn Ball - createball
Remove Ball - removeBall
Remove Turret - removeturret
Restart indicated level - restartlevel [number] or restartmap [number]
Should be a DSi ware!
This is the type of game i wanna see on the DSi. Awesome!


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DEFINITION of 'Issue'
1. The process of offering securities as an attempt to raise funds. Companies may issue bonds or shares to investors as a method of financing the business.
2. A series of stocks or bonds that have been offered to the public. A bond or stock issue relates to the set of instruments that were released under one offering.
INVESTOPEDIA EXPLAINS 'Issue'
1. The issuance of securities can take many forms. Companies may have a new issue, where securities are released for the first time, or a seasoned issue, where an established firm offers additional shares.
2. For example, let's say a company sells a group of 10-year bonds to the public. That set of bonds will be referred to as a single issue
New Issue
A reference to a security that has been registered, issued and ... -
Seasoned Issue
An issue of additional securities from an established company ... -
Unissued Stock
Stock that a company is authorized to issue but has never been ... -
Bonus Issue
An offer of free additional shares to existing shareholders. ... -
The issue or sale of a security by a company. It is often used ... -
Junior Issue
A corporate security that ranks lower in claim to another corporate ...
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Find out why price inelasticity of demand shows the relationship between demand and price if the price of an inelastic good is either lowered or raised. -
Reassessing Your Approach To Bond Investing
Rethinking your fixed-income portfolio may not resonate in quite the same way as dropping 10 pounds or finally giving up that smoking habit. -
Mutual Funds & ETFs
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Investing a portion of total assets in a cash position such as a money market account provides investors access to funds in the case of an emergency. -
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How does preferred stock differ from company issued bonds?
Discover the primary differences between preferred stock and corporate bonds, two income-generating investment vehicles issued by certain companies. -
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What is the difference between yield to maturity and the yield to call?
Determining various the various yields that callable bonds can provide investors is an important factor in the bond purchasing process.


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Comment: Not bad... (Score 2) 35
The list of nominees is actually pretty well-rounded. It would be nice to see Okami win an award or two, especially in light of Clover getting shut down.
Slashdot is powered by your submissions, so send in your scoop
"Consequences, Schmonsequences, as long as I'm rich." -- "Ali Baba Bunny" [1957, Chuck Jones]


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Rockstar News
Sipes Words: "The General" GNCC Round 2 / Mar.19.2014
"Round 2 at The General was a mess! It rained 2 inches the morning of the race and made the course pretty nasty. It was probably the worst mud I've ever ridden in. I got a decent start and worked my way up to 4th by mile 2 but had a goggle malfunction and had to pull in for a new pair, leaving me way behind the pack. I was playing catch up from then on, picking my way through guys and getting as high as 6th at one point. I was riding kind of cautious out there, there were mud holes that would swallow the bike if you weren't careful. I feel like I rode better at this race than round 1 though. My line choices and track vision are coming around. I lost all brakes with 2 laps to go, then got stuck in one of those seat deep ruts on the last lap and lost a few spots. I finished up 8th on the day. Not ideal, but with the problems I had, I was glad to finish in the top ten. I know I'm learning and getting better, and that makes me excited for the next race! I can't wait to see what's in store. A huge thanks goes out to all my sponsors for believing in me and sticking behind me as I learn the ropes of this crazy sport!"
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ZOTAC Amplifies GeForce GTX 780 for Faster and Quieter Performance
New ZOTAC GeForce GTX 780 AMP! Edition delivers superior quietness and insanely-fast performance
August 14, 2013 1:06 by anila
Dubai, UAE – August 14, 2013 – ZOTAC International, a global innovator and manufacturer of graphics cards, mainboards and mini-PCs, today amplifies the GeForce GTX 780 with a new Triple Silencer Enhanced Cooling system for superior quietness.
The insanely-fast ZOTAC GeForce GTX 780 AMP! Edition gives demanding gamers an extra performance edge for superior smoothness without sacrificing maximum visual quality or noise levels.
"Our engineers spent extra time fine-tuning the ZOTAC GeForce GTX 780 AMP! Edition to perfection," says Carsten Berger, senior director, ZOTAC International. "We took that extra time to push the base clock past 1 GHz for up to a 16-percent performance boost and topped it off with our brand new Triple Silencer enhanced cooling system. The result is an amazing graphics card that's faster and quieter."
A brand new ZOTAC Triple Silencer enhanced cooling solution that incorporates three quiet high-performance fans that reduce temperatures up to 10C and noise levels by 15dBA under heavy gaming loads is exclusive to the GeForce GTX 780 AMP! Edition. The ZOTAC Triple Silencer is finished off with signature orange fan blades and a black fan shroud for styling that looks as good as it performs.
It's time to play with the ZOTAC GeForce GTX 780 AMP! Edition!
General details
- New ZOTAC GeForce GTX 780 AMP! Edition graphics card
- NVIDIA GeForce GTX 780 GPU
- Engine clock: 1006 MHz (base)
- 1059 MHz (boost)
- 2,304 processor cores
- 3GB GDDR5 memory
- Memory clock: 6208 MHz
- 384-bit memory interface
- Triple Silencer Enhanced Cooling System
- PCI Express 3.0 interface
- NVIDIA GPU Boost 2.0 technology
- NVIDIA Surround capable
- NVIDIA FXAA & TXAA technology
- NVIDIA Adaptive Vertical Sync
- NVIDIA SLI (3-way) ready
- NVIDIA SHIELD gaming portable ready
- NVIDIA NVENC video transcoding acceleration capable
- DirectX 11.1 (feature level 11_0) technology & Shader Model 5.1
- OpenGL 4.3 compatible
- Blu-ray 3D ready
- Loss-less audio bitstream capable
- ZOTAC Boost Premium software bundle
- Nero Kwikmedia
- UNIGINE Heaven DX11 Benchmark
- ZOTAC Splinter Cell Compilation game voucher
- Splinter Cell Double Agent
- Splinter Cell Conviction
- Splinter Cell Blacklist (downloadable summer 2013)
Product Name |
ZOTAC GeForce GTX 780 AMP! Edition |
GPU | NVIDIA GeForce GTX 780 |
Engine Clock speed | 1006 MHz (base) |
1059 MHz (boost)Processor Cores2,304Shader ClockN/AMemory Clock speed6208 MHzMemory3GB GDDR5Memory interface384-bitDisplay Outputs2 x DL-DVI, DisplayPort, HDMIHDCPYesCoolingTriple Silencer (dual-slot)DirectX versionDirectX 11.1 (feature level 11_0) with Shader Model 5.1Other hardware featuresHardware accelerated Blu-ray 3D readySoftware FeaturesHardware Video Decode Acceleration Technology, NVIDIA CUDA technology, NVIDIA GPU Boost 2.0 technology, NVIDIA Adaptive Vertical Sync technology, NVIDIA Surround ready, OpenGL 4.3Windows capabilityWindows 7/8 ready
About ZOTAC International (MCO) Limited
ZOTAC International is a part of PC Partner Ltd. Group. ZOTAC is also one of the largest NVIDIA graphics cards and motherboard manufacturer in the world with over 10 years of quality manufacturing experience. The ZOTAC philosophy is to deliver the latest products at competitive prices without sacrificing quality.
For further information please visit www.zotac.com
ZOTAC International (MCO) Limited does not warrant the accuracy, completeness or reliability of information, materials and other items contained on this website or server. No liability is assumed with respect to the use of the information contained herein. When accessing this website, users acknowledge that ZOTAC International (MCO) Limited will not be liable in any event for any damages arising out of the use of this site or any websites linked to it.
While every effort has been taken to ensure accuracy and completeness in the preparation of this site, we assume no responsibility for errors or omissions. Products shown in this site are provided for general reference purposes only. All product information herein is subject to change without notice.
Copyright ã2013 ZOTACâ International (MCO) Ltd. All rights reserved. All company and/or product names may be trade names, trademarks and/or registered trademarks of the respective owners with which they are associated. Features, pricing, availability and specifications are subject to change without notice.
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David Beckham retires from soccer |
| Print | |
Thursday, May 16, 2013 |
New York Times: David Beckham announced he will retire from soccer at season's end. |
The city as startupGuest BlogWednesday, January 14, 2015 BY NISHANT BHAJARIA | OP-ED CONTRIBUTORStartups in the growth phase are associated with a fresh infusion of capital — human and financial — a curiosity factor and products to disrupt the market and drive demand. Portland's economy gives off the same aroma. Read more... |
The Human FactorFebruary 2015Monday, January 26, 2015 BY BRIAN LIBBYMatt French opens up South Waterfront. Read more... |
The short list: Holiday habits of six Oregon CEOsThe LatestThursday, December 11, 2014 BY JACOB PALMER | OB DIGITAL NEWS EDITORWe ask business and nonprofit leaders how they survive the season. Read more... |
Powerbook PerspectiveJanuary-Powerbook 2015Friday, December 12, 2014 BY LINDA BAKERA conversation with Oregon state economist Josh Lehner. Read more... |
Tackling the CEO-worker pay gapJanuary-Powerbook 2015Thursday, December 11, 2014 BY OREGON BUSINESS STAFFAn SEC rule targets the disparity between executive and employee compensation, reigniting a long-standing debate about corporate social responsibility. Read more... |
Closing the Gap: The two Oregons and the way forwardFebruary 2015Monday, January 26, 2015 BY JOE CORTRIGHT"Nostalgia is not an economic strategy." Read more... |
Dan and Louis Oyster Bar opens up to a changing neighborhoodThe LatestThursday, December 11, 2014 By MEGHAN NOLTVIDEO: Revamping a Classic — an iconic eatery stays relevant in a changing marketplace. Read more... |
Real Time - Oregon Business
TWITTER FEED Tweets by @OregonBusiness |
Legislative Preview: A Shifting Balance |
Tackling the CEO-worker pay gap |
Corner Office: Pam Edstrom |
Corner Office: Timothy Mitchell |
Justice for All |
Corner Office: Sheree Arntson |
Powerbook Perspective |
Is your business ready to join us in the call for action? This opening panel includes Oregon businesses who will discuss why they signed the Oregon Climate Declaration, the investments they are making to reduce carbon emissions, and how their actions are affecting their companies.
Get ready for two days of special events produced with the EPA, Portland Timbers and ISOS before and after the GoGreen Conference on October 16.
hubbub health uses behavior change science to rethink wellness programs.
In Ashland, a public-private partnership results in online resources to help diversify the local economy.
How sports tourism is driving economic growth and making cities across Oregon a better place to live.
If you have given a former employee access to your company's electronic information by virtue of assigning a desktop or laptop computer and you suspect he or she of having taken electronically stored data, there are several steps to follow to preserve electronic forensic evidence from spoliation.
The official launch will be Jan. 14.
In a switch on the traditional trade show, representatives from UO departments and local and state agencies will host tables to connect with businesses and vendors. The fourth Reverse Vendor Fair will take place Wednesday, Feb. 25, in Eugene.


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20 Jan 20:48 2015
Sorting rules for folder
Hello: I want to write a sorting rule for an IMAP folder in Becky, a folder in which emails sent from gmail on my computer or from gmail on my iphone end up and the, according to my rule, will be moved to a non-IMAP Becky folder. I understand that I must have a manual rule, since this is an IMAP folder ("messages are already there", in other words, they are not coming in or going out). However, I do not understand the box "Sorting Rules for This Folder". Are the only targets for sorting "Received Mail" or "Sent Mail"? What do these two labels denote? Thanks for some explanatory words. Hans L ------------------------------------ Posted by: Hans Leander <hansl@...> ------------------------------------ -- -- Plug-ins for Becky: http://groups.yahoo.com/group/beckymail/links/Plug_ins_001010085884 Upload a wish-list for Becky: http://groups.yahoo.com/group/beckymail/files/Wish-lists/(Continue reading)


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Tips for antiquing
I need some help on antiquing. Whenever i try to antique, i end up with colour all over the original paint. Although sometimes this looks good, its a pain when it looks awful and messes up your carefully painted sections!
I use watered down paint in a darker colour and wash it onto the area. Is this the right way to do it? If so, how do i stop staining on the main body of the paint?
Any help gratefully received!
Watered paint is fine. I believe that's what most people use. There is stuff you can buy to slow the dying of your paint but it's not necessary though.
If you clear coat before antiquing it helps the antique to wipe off cleanly. This also means you can fix mistakes or remove it completely alot easier if needed. Also if the paint is drying too fast try antiquing smaller areas.
Hope this helps.
After putting on the clear coat (and waiting a few days for it to really, really dry), I antique mixing 1/3 paint, 1/3 water and 1/3 antiquing medium (I buy mine at Michaels). It helps removing the excess, especially once it's a bit dry; you just use a humid sponge/paper towel/etc. With paint and water only, I think I'd find it harder to remove.
Nambroth (err, Jennifer) made a PYO tutorial. It has an antiquing section. It's not the only way to antique (I use a different method myself), but if you never read it, it's a great starter tutorial and provides a lot of helpful information =)
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So, to summarise. They fixed the facts, tortured the texts, invented the evidence, blitzed Blix, gelded Goldsmith, framed the French, wrecked Iraq and hanged Hussein.
What energy these people have, what a range of talents, it's hard not to admire them.
We had two interesting witnesses - Michael Wood the legal leader of the Foreign Office and one of his team members.
Elizabeth Wilmshurst is a formidable legal personality projected from remarkable moral structure. When the Attorney gave legal approval for the war she resigned. In civilian terms, there was something heroic about that, something most unusually admirable.
In the year before the war, all the legal advisers at the Foreign Office were of one opinion. This has probably never happened before. In private practice such unanimity constitutes professional malpractice. That is by the way. Going to war without a second UN resolution, all agreed, was illegal.
Every time ministers or officials alluded to regime change, Michael Wood wrote to them pointing out they were wrong. Once he wrote to Jack Straw telling him he was "completely wrong". And "occasionally you'd get the PM saying the wrong thing privately and I'd jump in." There was no deniability for any of them. They can't have liked that, not one bit.
When Wood sent a paper to Number 10 advising on the consequences of an illegal war the response came back, "Why has this been put into writing?"
A pretty straight kind of guy? Bad faith hardly starts to cover it.
The Attorney, it was said, was solid with the Foreign Office position: "I'm sure he was aware and agreed with it." He shared their reservations right up to his final decision ("the better view" as we heard it called).
So, Wood said, because the government knew what the Attorney's view was they didn't ask him for it.
Ms Wilmhurst said it was as though the legal opinion was an impediment, an obstacle. And it was "extraordinary" (in layman's terms, an effing scandal) that the legal OK wasn't sought before troops were deployed.
But life is a journey and with troops poised to invade, Goldsmith came to believe there was no need for a second resolution after all. This realisation came, we were told, through an interesting process. He didn't examine the text of the first resolution (that is, the famous 1441). Instead he talked to the people who negotiated it. By that means, he found out what they'd really intended.
Obviously the French negotiators wouldn't have known what was really intended so he didn't ask them.
He what? No, he didn't ask them.
Best question of the day came from Roderick Lyne: "Should the Attorney give draft advice, thereby opening up a process of negotiation?"
What a polite way of putting it.
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