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Texas Politics
All Texas politics all the time from the San Antonio Express-News and Houston Chronicle
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Perry adds congressional redistricting to special session
This morning, the Republican legislative leadership released a congressional redistricting plan that splits Travis County into five Congressional districts. This afternoon, Gov. Rick Perry added it to the call, effectively killing the collective press corps dream for a short special session. – Nolan Hicks A statement from the governor did not accompany the release of […] [Read More]
Math says use the Rainy Day Fund, lawmaker says
House Appropriations member Rep. Ruth Jones McClendon, D-San Antonio, offers her view on the state's Rainy Day Fund: Your Texas legislature has just completed the 140-day marathon known as the Regular Legislative Session. We have been called back for a Special Session by the Governor, mainly to decide what to do about funding our public […] [Read More]
A moment can change everything
After spending the last 140 days trying to find a way to crystallize their opposition to the Republican budget, Democrats got the gift of the session from the filibuster given by the woman who has nothing to lose. Sen. Wendy Davis, D-Fort Worth, who had already lost her district to redistricting, managed to become the […] [Read More]
Dewhurst wants anti-groping bill added to special session
Lt. Gov. David Dewhurst late Sunday sent Gov. Rick Perry a letter with a list of bills he would like to see included in the special session, including the controversial "anti-groping bill" that Sen. Dan Patrick blamed Dewhurst for defeating. Patrick said Monday evening that he spoke with Dewhurst about petitioning the governor to add […] [Read More]
Dems say they're standing up for convictions
Shortly after Lt. Gov. David Dewhurst announced that the governor had called a special session for Tuesday morning and then gaveled the 82nd regular session to an anticlimactic end, Senate Democrats gathered at the press table and ruminated about what the filibuster by state Sen. Wendy Davis the night before had wrought and what they […] [Read More]
Dewhurst: Special session tomorrow after school finance fails
Lt. Gov. David Dewhurst said GOP leaders couldn't resurrect a school finance plan and will be back in a special session in the morning. "As hard as I've tried, we have not been able to get an agreement to suspend the rules, so we will be back tomorrow morning," Dewhurst said. The chamber adjourned minutes […] [Read More]
Van de Putte concerned over potential special session scope; Ogden says there's a risk education funding could be cut
Sen. Leticia Van de Putte, head of the Senate Democratic Caucus, didn't give a yes or no when asked if she may vote with Republicans to resurrect a school funding bill and avoid a special session that could be packed with issues Democrats don't like. Senate leaders need a 4/5 vote, or 25 of the […] [Read More]
House Democrats on sideline; won't pledge to Speaker Straus – for now
ouse Speaker Joe Straus might have to delay the customary ritual of collecting colleague pledges of support for re-election. Democrats are collecting signatures on a letter asking Democratic House members to delay pledging support to the San Antonio Republican. "We should not be so eager to give up the authority given to us by our […] [Read More]
Tuesday special session likely for Legislature
State Sen. Wendy Davis, D-Fort Worth, began a filibuster late Sunday to kill a crucial school finance legislation that she believes will create inequities in public school financing, harshly criticizing the Legislature's plan to cut $4 billion owed to school districts under current law. Lt. Gov. David Dewhurst called her decision to kill the measure […] [Read More]
General Texting Ban Survives Floor Maylay
The Texas House voted to back a ban on 'texting while driving' after more than an hour of sometimes contentious floor debate that featured Rep. Tom Craddick facing off against some of his usual allies on the floor. "This is about saving lives and preventing accidents," said Rep. Craig Eiland, D-Galveston, who said that he […] [Read More]
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Deep Roots, Lush Leaves – Transformation of Hmong Dance in Minnesota
Deep Root, Lush Leaves – Transformation of Hmong Dance in Minnesota
"Only by Deepening the Roots, We Can Expect the Lush Leaves."
~ Dr. Nengher N. Vang
The "Deep Root, Lush Leaves – Transformation of Hmong Dance in Minnesota" Multimedia Exhibition is presented from June 1st to July 28, 2013 at the University of MN Urban Research and Outreach Center (UROC) Gallery (2001 Plymouth Ave N, Minneapolis MN 55411). A series of events will be hosted throughout this 2 months of exhibition:
1. Multimedia Gallery Exhibition and Opening Reception
Date: June 27th (Thursday), 2013, 5pm – 8pm
FREE and open to the public
5pm * Opening Reception
6pm * Exhibition Introduction and Asian Dance Performance
2. Hmong Costume Fashion Show and Discussion Panel
Date: July 27th (Saturday), 2013, noon -3pm
FREE and open to the public
Noon * Fashion Show
2pm * Panel Discussion
This Multimedia Exhibition explores the complex history of Hmong Dance from China, to Southeast Asia to the United States. It examines, in particular, the transformation of Hmong dancing through their migration, encounter, and interaction with outside groups, including the Chinese, the Lao, the Thai, the Vietnamese, and finally the settlement in America. To examine such transformative history of Hmong Dancing, however, one also has to examine the changing history of Hmong Traditional Costume style, because the change of Hmong Dress significantly affected the Transformation of Hmong Dance.
This Exhibition presents a parallel vision of Hmong Costumes and Dances from its origin and to its evolution in America. It shows that, throughout their long history of immigration, the Hmong have incorporated dress styles, music, dances, and other artistic expressions with outside groups' cultures, and to integrate into as their own distinctive styles. Today, especially at New Year Celebrations in places such as St. Paul, Minnesota, and Fresno, California, Hmong men and women in a variety of dress style can be seen dancing to music and in dance style appropriated from a variety of cultures.
This Transformative Hmong Dance History reflects in the old saying, – "Only by Deepening the Roots, We Can Expect the Lush Leaves." This Exhibition shows that, throughout their long and complex history, the Hmong have integrated dress styles, music, dances, and other artistic expressions from outside groups and cultures to create their own dress, music, and dance. Such hybridity of Hmong Dance shows not only the evolution of Hmong culture over time but also the incredible resilience of the Hmong. That is, not only does the Hmong, stateless people, survive years of warfare and displacement, their culture also has not died off, as some have feared, but merely evolved over time, and celebrated in a proud way. And this Exhibition represents the true reflections of such lush leaves from the deepest Hmong dance roots.
This Exhibition is curate by the Iny Asian Dance Theater's Artistic Director – Iny Xiong, Coordinators – See Xiong and Ange Hwang; and the Photos are contributed by the well-known Hmong Photographers – Nolan Lee and Cam Xiong. Special thanks for the write up of this cultural interpretation – "Transformative History of Hmong Dress, Music, and Dance," by Dr. Nengher N. Vang (Elizabeth City State University)
This project is supported in part by University of MN, UROC, and MN State Arts Board. This activity is made possible in part by a grant provided by the Minnesota State Arts Board through an appropriation by the Minnesota State Legislature from the State's arts and cultural heritage fund with money from the vote of the people of Minnesota on November 4, 2008.
For more information please contact: email@example.com or 612-376-7715 or email@example.com
Beading Works on the Hmong Dance Costume
Hmong Story Cloth portraying the Hmong Dance Competition
One Response to "Deep Roots, Lush Leaves – Transformation of Hmong Dance in Minnesota"
I like it when individuals come together and share opinions.
Great website, continue the good work!

subset: commoncrawl


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Small animal imaging with human PET
Bahri, Mohamed Ali ; ; Warnock, Geoffrey et al
Poster (2012, September)
PET studies provide valuable information in the assessment of animal models for human diseases. MicroPET systems provide the high resolution needed to explore small organs but suffer from a reduced axial ... [more ▼]
PET studies provide valuable information in the assessment of animal models for human diseases. MicroPET systems provide the high resolution needed to explore small organs but suffer from a reduced axial FOV. Multiple bed positions are then used to obtain whole body scans resulting in increased scan time and incomplete dynamic data. In contrast, human PET systems have larger axial FOV but a lower resolution. In this study, an image-based model of the scanner spatial response function combined with a 3D-OSEM reconstruction algorithm were used to improve spatial resolution of the Siemens ECAT EXACT HR+ PET scanner. A stationary double Gaussian model [1] of the ECAT EXACT HR+ point spread function was derived from 18F point source measurements performed at different radial and axial locations in the scanner FOV. This model was used in a 3D-OSEM reconstruction (3D-OSEM-RM). Sinograms were normalized and attenuation and scatter corrected using the Siemens ECAT tools before reconstruction. Both NEMA NU 2-1994 performance phantoms and NEMA NU4-2008 image quality phantom mimicking small animals were used to evaluate the accuracy of corrections for physical effects and the overall image quality. A 50 min dynamic FDG rat study was conducted on the ECAT HR+ and reconstructed with 3D-OSEM-RM. The images were used to compute the metabolic rate of glucose (MRglu) in multiple brain structures. These images were also visually compared to the static image obtained with a FOCUS 120 microPET immediately after the HR+ dynamic scan. The standard deviations of the two Gaussians used to model the transaxial (axial) resolution in a central FOV of 5 cm radius were σ1 = 1.6 (2.75) mm and σ2 = 3.66 (4.16) mm, and the ratio of the weights between the first and second Gaussians was ρ = 0.2 (0.7). Image uniformity and accuracy of scatter and attenuation corrections, evaluated following NEMA NU 2-1994, were found to be very similar between 3D-OSEM, 3D-OSEM-RM, 2D- and 3D-FBP reconstructed images. When using the NEMA NU4-2008 image quality phantom a significant increase of the hot rod recovery coefficient was observed. This effect was rod size dependent and amounted to 17-35% for the 3D-OSEM-RM compared to the 3D-OSEM and to 35-62% compared to the FBP reconstructions. Nevertheless the values obtained with 3D-OSEM-RM were around 20-35% lower than those obtained with the FOCUS 120 microPET scanner. Most of the small brain structures observed on microPET images were also visible on the images obtained with the HR+ scanner and 3D-OSEM-RM. Rat cerebral MRglu values calculated on 3D-OSEM-RM images were in the range of published values [2] (e.g. whole brain = 25.34 μmol/min/100g). Using an approximate model of the ECAT EXACT HR+ spatial response in 3D-OSEM resulted in sufficient image quality for dynamic whole body scans of small rodents, despite the large FOV, and resulted in improved contrast compared to images generated using the built-in software. This methodology will be applied for future small animal dosimetry and modeling studies in our laboratory. [1] Comtat et al. IEEE Nucl Sci Symp Conf Record. pp. 4120-4123 (2008) [2] Schiffer et al. J Nucl Med 48:277-287 (2007) [less ▲]Detailed reference viewed: 144 (15 ULg)
Dosimetry for 6-[18F]Fluoro-L-DOPA in humans based on in vivo microPET scans and ex vivo tissue distribution in mice
Bretin, Florian ; Warnock, Geoffrey ; Bahri, Mohamed Ali et al
Poster (2012, September)
Radiation dosimetry of new radiopharmaceuticals generally starts with studies in small animals such as mice and rats. The traditional technique has long been ex vivo measurement of the biodistribution ... [more ▼]
Radiation dosimetry of new radiopharmaceuticals generally starts with studies in small animals such as mice and rats. The traditional technique has long been ex vivo measurement of the biodistribution over time using harvested organs at different times post administration of the radiopharmaceutical. Since this approach requires a significant amount of animals, dynamic microPET studies, where the biodistribution of the tracer over time can be determined in vivo in a single scan, are an invaluable alternative. Due to known imaging artifacts and limitations, such as partial volume effect, a hybrid technique combining harvesting organs (post-scan) and dynamic imaging was introduced to achieve a cross-calibration to account for these limitations. Since 6-[18F]Fluoro-L-DOPA is a widely used PET tracer to study the dopaminergic system in neurology and oncology and there is no sound published dosimetry data, absorbed doses for major organs in humans were estimated using the traditional ex vivo technique and by dynamic microPET imaging in mice, allowing direct comparison of the results from the two techniques. The tissue distribution over time of 6-[18F]Fluoro-L-DOPA was determined by radioassay of harvested organs at 2, 5, 10, 30, 60, 120 minutes post administration (n=5 at each time point) in isoflurane-anaesthetized mice. Dynamic PET images were acquired with a FOCUS 120 microPET for 120 minutes after injection of 6-[18F]Fluoro-L-DOPA followed by radioassay of harvested organs (n=4). A bladder voiding scenario was used to simulate excretion every 2 h. The organ time-activity-curves (TACs) from both methods were extrapolated from a simulated 35 g standard mouse to a 70 kg standard male human using a technique based on organ to bodyweight ratios. The absorbed doses in major human organs were calculated with the commercially available human dosimetry software OLINDA/EXM (Version 1.1) using the extrapolated TACs. The extrapolated organ TACs obtained using the two methods showed a high correlation (average r = 0.94 ± 0.05, p < 0.001). However, TACs from PET alone under- or overestimated the activity in individual organs in contrast to TACs obtained using the cross-calibration of the PET data with the activity in post-scan dissected organs. Those organs in the excretion pathways, comprising bladder wall, kidneys and liver, received the highest organ doses. The total body absorbed dose was 0.0118 mGy/MBq for both the imaging based and harvesting based methods. The effective dose was 0.0193 mSv/MBq for the hybrid imaging-harvesting technique and 0.0189 mSv/MBq for the pure harvesting technique. Scaling errors in the PET TACs are likely caused by quantification errors such as partial volume effects and image artifacts. The use of a hybrid imaging technique to cross-calibrate the TACs improved the accuracy of the imaging-based dosimetry estimates. Therefore the hybrid technique combining dynamic imaging and harvesting organs (post-scan) is a suitable alternative to the gold standard ex vivo radioassay method. It yields comparable results yet reduces significantly the amount of animals needed in the study and can accelerate data acquisition. [less ▲]Detailed reference viewed: 84 (20 ULg)
PET In Conscious Rodents - Quantification of Stress During The Training Process
Warnock, Geoffrey ; Bahri, Mohamed Ali ; Bretin, Florian et al
Poster (2012, September)
Recently several methods for performing PET studies in conscious rodents have been developed [1-3]. These methods have the potential to greatly improve the translational nature of PET studies in rodents ... [more ▼]
Recently several methods for performing PET studies in conscious rodents have been developed [1-3]. These methods have the potential to greatly improve the translational nature of PET studies in rodents. One of the most easily implemented methods is the training of a rat to tolerate head fixation in a restraining device. Training consists of intervals of restraint over several days. However, the stress induced by this training procedure has not been quantified in detail. Limited changes in plasma corticosterone have been reported, but this data may be confounded by sample timing and baseline levels. An implantable telemetry system (Telemetry Research) was used to remotely measure blood pressure, heart rate and core temperature during training. Transmitters were implanted in the abdominal cavity under isoflurane anesthesia, with the blood pressure sensor fixed in the abdominal aorta. Training was started after a recovery period of at least 1 week. Training consisted of a 5 min period of acclimatization in the cage containing the restraining device, followed by increasing durations of restraint in the device on subsequent training days (15, 30, 45, 60, 90 min). Telemetry data was acquired from 5 min prior to acclimatization to 60 minutes post-training. In this initial pilot study, a single rat was trained, without head fixation, for 4 consecutive days and again on day 7. All reported values are mean ± SEM across the five training days. In the home cage, prior to acclimatization, baseline heart rate (HR) was 294 ± 15 bpm. During the acclimatization period, HR was elevated to 411 ± 7 bpm. Immediately after starting training, HR was 419 ± 16 bpm. During the training period HR showed a tendency to decrease, with raised periods at undefined intervals. After return to the home cage, HR remained elevated for 15-20 min before returning to a value (313 ± 9 bpm) close to baseline. A similar pattern was seen in blood pressure (mean; BP). Baseline BP was 76 ± 7 mmHg, increasing to 94 ± 9 mmHg during acclimatization. After commencing training, a peak in BP was reached at 102 ± 8 mmHg. After the 15-20 min recovery interval, BP returned to a baseline of 77 ± 9 mmHg. The HR and BP responses to acclimatization and to the training protocol persisted throughout all training days, with the main noticeable difference being the number of bouts of increased HR, which increased with training duration. Core body temperature (baseline: 37.45 ± 0.21 °C) increased during restraint training, with a subsequent post-training peak (38.21 ± 0.03 °C). Measurement of core temp is complicated during longer training sessions by the need to charge the transmitter. This early data indicates that stress induced by the training procedure for conscious PET persists after several days of training. In subsequent studies the head will be fixed and the effect of the training on plasma corticosterone and central glucose metabolism (using [18F]FDG) will be examined. [1] Momosaki et al. (2004) Synapse 54:207–213 [2] Wyss et al. (2009) NeuroImage 48:339–347 [3] Itoh et al. (2009) J Nucl Med 50:749–756 [less ▲]Detailed reference viewed: 51 (18 ULg)
Imaging Guided Proteomics Unveils Heterogeniety in Colorectal Carcinoma Liver Metastases – Implications for Targeted Therapies.
; Turtoi, Andrei ; Delvaux, David et al
in Proceedings Giga Day 2012 (2012, May 04)Detailed reference viewed: 43 (21 ULg)
Fast and reliable method for the preparation of ortho- and para-[18F]fluorobenzyl halide derivatives: Key intermediates for the preparation of no-carrier-added PET aromatic radiopharmaceuticals
Lemaire, Christian ; Libert, Lionel ; Plenevaux, Alain et al
in Journal of Fluorine Chemistry (2012), 138Detailed reference viewed: 42 (12 ULg)
NEMA NU4-2008 Performance Evaluation for the MicroPET FOCUS 120 and Iodine-124
Taleb, Dounia ; Bahri, Mohamed Ali ; Warnock, Geoffrey et al
in IEEE proceedings of ANIMMA 2011 (2012, March 12)Detailed reference viewed: 49 (22 ULg)
X-ray Dose Quantification for Various Scanning Protocols with the GE eXplore 120 micro-CT
Bretin, Florian ; Bahri, Mohamed Ali ; Warnock, Geoffrey et al
Poster (2012)Detailed reference viewed: 60 (26 ULg)
Performance evaluation of the General Electric eXplore CT 120 micro-CT using the vmCT phantom.
Bahri, Mohamed Ali ; Warnock, Geoffrey ; Plenevaux, Alain et al
in Nuclear Instruments & Methods in Physics Research Section A (2011), 648
The eXplore CT 120 is the latest generation micro-CT from General Electric. It is equipped with a high power tube and a flat panel detector. It allows high resolution and high contrast fast CT scanning of ... [more ▼]
The eXplore CT 120 is the latest generation micro-CT from General Electric. It is equipped with a high power tube and a flat panel detector. It allows high resolution and high contrast fast CT scanning of small animals. The aim of this study was to compare the performance of the eXplore CT 120 with the one of the eXplore Ultra, its predecessor for which the methodology using the vmCT phantom was already described [1]. The phantom was imaged using typical rat (fast scan or F) or mouse (in vivo bone scan or H) scanning protocols. With the slanted edge method, a 10% modulation transfer function (MTF) was observed at 4.4 (F) and 3.9-4.4 (H) mm-1 corresponding to 114 μm resolution. A fairly larger MTF was obtained with the coil method with the MTF for the thinnest coil (3.3 mm-1 ) equal to 0.32 (F) and 0.34 (H). The geometric accuracy was better than 0.3%. There was a highly linear (R2 > 0.999) relationship between measured and expected CT numbers for both the CT number accuracy and linearity sections of the phantom. A cupping effect was clearly seen on the uniform slices and the uniformity-to-noise ratio ranged from 0.52 (F) to 0.89 (H). The air CT number depended on the amount of polycarbonate surrounding the area where it was measured: a difference as high as approximately 200 HU was observed. This hindered the calibration of this scanner in HU. This is likely due to the absence of corrections for beam hardening and scatter in the reconstruction software. However in view of the high linearity of the system, the implementation of these corrections would allow a good quality calibration of the scanner in HU. In conclusion, the eXplore CT 120 achieved a better spatial resolution than the eXplore Ultra (based on previously reported specifications) and future software developments to include beam hardening and scatter corrections will make the new generation CT scanner even more promising. [less ▲]Detailed reference viewed: 266 (40 ULg)
Use of a beta microprobe system to measure arterial input function in PET via an arteriovenous shunt in rats
Warnock, Geoffrey ; Bahri, Mohamed Ali ; Goblet, David et al
in European Journal of Nuclear Medicine and Molecular Imaging Research (2011), 1
Kinetic modeling of physiological function using imaging techniques requires the accurate measurement of the time-activity curve of the tracer in plasma, known as the arterial input function (IF). The ... [more ▼]
Kinetic modeling of physiological function using imaging techniques requires the accurate measurement of the time-activity curve of the tracer in plasma, known as the arterial input function (IF). The measurement of IF can be achieved through manual blood sampling, the use of small counting systems such as beta microprobes, or by derivation from PET images. Previous studies using beta microprobe systems to continuously measure IF have suffered from high background counts. In the present study, a light-insensitive beta microprobe with a temporal resolution of up to 1 s was used in combination with a pump-driven femoral arteriovenous shunt to measure IF in rats. The shunt apparatus was designed such that the placement of the beta microprobe was highly reproducible. The probe-derived IF was compared to that obtained from manual sampling at 5-s intervals and IF derived from a left ventricle VOI in a dynamic PET image of the heart. Probe-derived IFs were very well matched to that obtained by "gold standard" manual blood sampling, but with an increased temporal resolution of up to 1 s. The area under the curve (AUC) ratio between probe- and manually derived IFs was 1.07 ± 0.05 with a coefficient of variation of 0.04. However, image-derived IFs were significantly underestimated compared to the manually sampled IFs, with an AUC ratio of 0.76 ± 0.24 with a coefficient of variation of 0.32. IF derived from the beta microprobe accurately represented the IF as measured by blood sampling, was reproducible, and was more accurate than an image-derived technique. The use of the shunt removed problems of tissue-background activity, and the use of a light-tight probe with minimal gamma sensitivity refined the system. The probe/shunt apparatus can be used in both microprobe and PET studies. [less ▲]Detailed reference viewed: 62 (19 ULg)
Bahri, Mohamed Ali ; Taleb, Dounia ; Warnock, Geoffrey et al
Poster (2011, May 29)Detailed reference viewed: 27 (6 ULg)
Evaluation des performances du microPET Siemens FOCUS 120 pour l'Iode 124 en utilisant la norme NEMA NU4-2008
Taleb, Dounia ; Bahri, Mohamed Ali ; Warnock, Geoffrey et al
Poster (2011, May 07)Detailed reference viewed: 48 (19 ULg)
Reliability in kinetic modeling of [18F]fallypride binding in the mouse brain: application of test-retest method
Geuzaine, Annabelle ; Bahri, Mohamed Ali ; Warnock, Geoffrey et al
Poster (2011, May)Detailed reference viewed: 31 (6 ULg)
[18F]fallypride binding in the mouse brain: test-retest and effects of registration
Bahri, Mohamed Ali ; Geuzaine, Annabelle ; Warnock, Geoffrey et al
Conference (2011, January 17)
The quantification of in vivo receptor kinetics with PET tracer experiments is an intricate and challenging problem especially for small animals such as rats and mice. A test-retest scan is usually set up ... [more ▼]
The quantification of in vivo receptor kinetics with PET tracer experiments is an intricate and challenging problem especially for small animals such as rats and mice. A test-retest scan is usually set up in order to confirm an observed experimental effect or to examine the reliability of the experiment design. Inadequate processing of the image data may also mask small effects. The purpose of this study was to investigate the effect of image registration on [18F]fallypride binding potentials calculated from PET mouse test-retest data. Sub-optimal registration affected the quantification of in vivo receptor kinetics with [18F]fallypride. The absence of anatomical information in the [18F]fallypride image and the lack of a homogeneous tracer distribution, even during the earlier minutes of the scan, lead to erroneous automatic registration. A FDG scan after each [18F]fallypride test could improve registration as FDG provides a more homogeneous brain image. Variability in the data could also result from stress induced by anaesthesia or the experimental environment. [less ▲]Detailed reference viewed: 117 (24 ULg)
Image Quality evaluation for 124I in the microPET Focus 120 scanner using the NEMA NU4-2008 phantom
Bahri, Mohamed Ali ; Warnock, Geoffrey ; Taleb, Dounia et al
Conference (2011, January 17)
Physical properties of iodine-124 such as its high positron energy, corresponding large positron range in tissue and the fraction of the single γ-photons emitted may have detrimental effects on the PET ... [more ▼]
Physical properties of iodine-124 such as its high positron energy, corresponding large positron range in tissue and the fraction of the single γ-photons emitted may have detrimental effects on the PET image quality. The purpose of this work was to evaluate the image quality for iodine-124 in the small animal microPET Focus 120 scanner using the NEMA NU4-2008 image quality phantom. Although the 2 ns timing window gives higher recovery coefficients and slightly lower spill-over ratios and combined with the 350-590 keV energy window gives the lowest spill-over ratio, the combination of the 350-650 keV and 6 ns windows seems to be the best compromise to obtain images with high contrast and low noise content. [less ▲]Detailed reference viewed: 99 (5 ULg)
Memantine-induced brain activation as a model for the rapid screening of potential novel antipsychotic compounds: Exemplified by an mGlu2/3 receptor agonist
; ; et al
in Society-for-Neuroscience Abstracts/Annual Meeting Publications (2010, November 17), 40
Schizophrenia is a severe, disabling chronic disorder affecting approximately 1% of the population. Unfortunately, patients afflicted by this difficult to treat psychiatric illness remain stigmatized and ... [more ▼]
Schizophrenia is a severe, disabling chronic disorder affecting approximately 1% of the population. Unfortunately, patients afflicted by this difficult to treat psychiatric illness remain stigmatized and are likely to suffer permanent cognitive and social deficits. Improvements and development of more robust and hopefully predictive screening assays for this disease should enhance the identification and development of novel treatments. The present study describes a rapid and robust method for the testing of potential novel antipsychotics by utilising a simplified [14C]2-deoxyglucose (2-DG) uptake autoradiography technique following memantine-induced brain activation. Male C57BL/6JCRL mice were treated with either vehicle, ketamine (30 mg/kg, s.c.) or memantine (20 mg/kg, s.c.). Both NMDA antagonists induced significant increases in 2-DG uptake in specific brain region such as lateral orbital cortex, olfactory tubercle, piriform cortex, cingulate cortex, retrosplenial cortex, lacunosum molecular layer of the hippocampus and the lateral posterior thalamic nucleus. Interestingly, memantine elicited a more robust brain activation signature with a larger dynamic window than ketamine. For further characterisation of the assay, we also tested the effect of diet (fasting versus non-fasting) and different vehicles. In addition, dedicated software, developed particularly for this assay, was evaluated for automated quantification of the brain sections. In subsequent reversal studies, we found that in accordance to the ketamine challenge model (Duncan et al. 1998), the "atypical" anti-psychotic clozapine (2.5 and 10 mg/kg, s.c.) significantly reversed memantine-induced 2-DG uptake whilst the "typical" anti-psychotic haloperidol (0.32 mg/kg, s.c.) was inactive thus further validating our choice of memantine for the challenge agent. An additional study then determined the effects of a mGlu2/3 receptor agonist on both ketamine and memantine-induced brain activation. Pre-treatment with LY404039 (10 mg/kg, s.c.) fully reversed both the ketamine and memantine-induced increase in 2-DG uptake without effects on basal 2-DG uptake. Finally, a small animal PET study was performed with [18F]-FDG in mice and rats investigating the effect of memantine (20 mg/kg) administration in vivo. This study confirmed the memantine-induced brain activation previously demonstrated by autoradiography. In conclusion, this novel pre-clinical method shows potential for the screening of compounds targeting the NMDA receptor hypofunction hypothesis of schizophrenia and may assist in translating these findings from the bench to clinic. [less ▲]Detailed reference viewed: 67 (7 ULg)
Warnock, Geoffrey ; Bahri, Mohamed Ali ; Goblet, David et al
Poster (2010, September)Detailed reference viewed: 33 (15 ULg)
Kinetic modelling of 18F-fallypride binding to dopamine receptors – a comparison between beta microprobe and microPET
Warnock, Geoffrey ; Bahri, Mohamed Ali ; Goblet, David et al
Poster (2010, September)Detailed reference viewed: 25 (6 ULg)
Warnock, Geoffrey ; ; Bahri, Mohamed Ali et al
Poster (2010, September)Detailed reference viewed: 37 (8 ULg)
Warnock, Geoffrey ; ; Bahri, Mohamed Ali et al
Poster (2010, September)Detailed reference viewed: 33 (10 ULg)
Click chemistry : radiolabelling of oligonucleotides with fluorine- 18 for PET
Kaisin, Geoffroy ; Flagothier, Jessica ; Mercier, Frédéric et al
Poster (2010, June)
Oligonucleotides (ONs), especially small interfering RNA (siRNA), are promising therapeutic agents, but their pharmacokinetics and biodistributions are widely unknown. Positron Emission Tomography (PET ... [more ▼]
Oligonucleotides (ONs), especially small interfering RNA (siRNA), are promising therapeutic agents, but their pharmacokinetics and biodistributions are widely unknown. Positron Emission Tomography (PET) using fluorine-18 is a suitable technique to image and quantify such biological processes. The challenge for the radiochemist is to introduce this short half-life isotope (t1/2(18F)=109.7 min) onto oligonucleotides or, more generally, biomolecules. The most common technique requires the coupling of a prosthetic group bearing the radiotracer with the biomolecule. Current methods for labeling ONs with fluorine-18 have sub-optimal yields and require a long synthesis time.1 Click chemistry, e.g. 1,3-dipolar Huisgen cycloaddition of azides to alkynes, could be an efficient way to increase yields and reduce synthesis time. Conjugations with ONs are usually performed at 3'-ends using a well-chosen linker in order to limit degradation by exonucleases and to avoid alteration of hybridization properties and siRNA gene silencing efficiency. This also allows the development of universal solid supports used for the solidphase synthesis of ONs. Here we report the synthesis of three alkyne-bearing linkers , the synthesis and radiosynthesis of the complementary azido-bearing prosthetic groups (1-(azidomethyl)-4-[18F]- fluorobenzene) and coupling with functionalized ONs. [less ▲]Detailed reference viewed: 141 (32 ULg)


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Western Refining Declares Special Dividend Of $1.50 Per Share
EL PASO, Texas, Dec. 11, 2012 (GLOBE NEWSWIRE) -- Western Refining, Inc. (NYSE:WNR) today announced that on December 10, 2012, its Board of Directors declared a special cash dividend in the amount of $1.50 per share, payable on December 28, 2012, to shareholders of record at the close of market on December 21, 2012.
Jeff Stevens, CEO and President of Western Refining, said, "The decision by our Board of Directors to declare a second 2012 special dividend reflects our on-going commitment to our shareholders. Our margin environment continues to be very strong. The Permian Basin crude oil discount significantly widened in December and continues to widen into 2013. This environment, coupled with our aggressive debt reduction, conservative capital structure, and on-going hedging initiative, allows the Company to continue to return cash to shareholders via dividends and our share repurchase program. In 2012, Western will return over $320 million to its shareholders. These actions, and our continued investment in the business, reinforce our commitment to create value for Western's shareholders."
About Western RefiningWestern Refining, Inc. is an independent refining and marketing company headquartered in El Paso, Texas. Western operates refineries in El Paso, and Gallup, New Mexico. Western's asset portfolio also includes stand alone refined products terminals in Albuquerque and Bloomfield, New Mexico; asphalt terminals in Phoenix and Tucson, Arizona, Albuquerque, and El Paso; retail service stations and convenience stores in Arizona, Colorado, New Mexico and Texas; a fleet of crude oil and finished product truck transports; and wholesale petroleum products operations in Arizona, California, Colorado, Maryland, Nevada, New Mexico, Texas, and Virginia. More information about the Company is available at www.wnr.com . The Western Refining, Inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=7615 Cautionary Statement on Forward-Looking Statements This press release contains forward-looking statements which are protected as forward looking statements under the Private Securities Litigation Reform Act of 1995. The forward-looking statements contained herein include statements about future: margin environments, Permian Basin crude oil discounts, ability to reduce debt aggressively or at all, conservativeness of our capital structure, hedging initiatives, return of cash to shareholders, dividends, share repurchases, investments in our business and value to Western shareholders. These statements are subject to the general risks inherent in our business and may or may not be realized. Additional information relating to the uncertainties affecting Western's business is contained in its filings with the Securities and Exchange Commission. The forward-looking statements are only as of the date made, and Western does not undertake any obligation to (and expressly disclaims any obligation to) update any forward-looking statements to reflect events or circumstances after the date such statements were made, or to reflect the occurrence of unanticipated events.
CONTACT: Investor and Analyst Contact: Jeffrey S. Beyersdorfer (602) 286-1530 Media Contact: Gary Hanson (602) 286-1777
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Sesame Street Season 45
Sesame Street's 45th season officially begins Monday September 15. After you see the new episodes, post here and let us know your thoughts.
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Toyota Camry: Problems & Solutions
Help Anyone,
I have posted this problem before, so my problem is engine noise when the vehicle is in gear. The dealership told me it was the drive belt, because when they removed the belt the slapping/tapping noise went away. They did replace the belt, but the noise is still there, and getting worse. Does anyone know if there is a fix for this, or is anyone else experiencing this problem? Thanks in advance. The Camry is a 4 cylinder XLE auto, and the vehicle has about 1000 miles.
Thanks Again
My wife and I have been experiencing vague a arbitrary shifted of my 2003 Camry V6 LE for about a year. I had taken it back to the local dealer where we bought twice in the past year. The tech and the dealership owner both test drove the car and both said they could not duplicate any of the problems I described. Last week the car was taken to a dealership that is more than 50 miles from where we live. After a brief test drive the tech check the fluid level and found it to be over filled. He indicated he had to drain almost 0.9 quarts of fluid from the transmission. When I drove the car away from the dealership I noticed an immediate difference. It no longer hesitated when accelerating from a dead stop and shifts from 1st to 2nd and 2nd to 3rd seemed more normal. By more normal I mean that the engine would rev in each gear rather than sometimes abruptly shifting to the next higher gear. The car went from being (for me) annoying to drive to being pleasant to drive.
I had written Toyota Customer Service in December 2004 about the car and their position was "if the Dealership cannot duplicate the problem they cannot fix it." Now my concern is what damage has been done after driving with the transmission over filled. Guess I will write them again for an explanation and ask for an extension my warranty. One more thing I noticed is my Owners Manual does not have a procedure for checking automatic transmission fluid level!
jdeib Posts: 70If you are interested in removing the dash to install a new stereo system, try Crutchfield.com, the stereo supplier. They have detailed directions that you can purchase from them for your Camry. It details how to remove the dash panel to get to the receiver and it also shows how to remove the door panels to replace the speakers. It would be alot cheaper than buying a shop manual if you are needing to just install the stereo.
Maybe not. Check my post on our 2003 Camry V6 LE 5spd automatic (nowoldmech), then check your transmission fluid level. Since there does not appear to be a procedure for this in the Owners Manual, if your not familiar with the procedure find a friend who is. If it is at all over filled take it to your Toyota dealer. I would be interested in what you find.
Sounds like a familiar story. Hesitation when starting from a dead stop, abrupt shifts from 1st to 2nd and 2nd to third. How about this symptom: at low throttle and you try to accelerate it seems the transmission is momentarily not in gear then abruptly shifts into gear. Or how about: sometimes when trying to merge into freeway traffic and you try to quickly accelerate but passing gear is flat with no increase in either power or acceleration! If these symptoms sound familiar then read my post on our 2003 Camry (nowoldmech). There is hope but first make sure you transmission was not over filled. I would be interested to hear what you find. Hope your problems turn out to be as simple.
hatedealers Posts: 9I think you have hit the nail on the head, hatedealers.
Never had a car that did this before.
It seems to be getting better over time.
Car now has 2100 miles on it and the lurch is still there but
much gentler.
It used to feel like it was always being rear-ended when I stopped
at a light, which was not a good feeling as it would cause a panic reaction
in me, having been rear-ended three times in the past.
I love this car otherwise except that every other car on the road looks just like it.
I got the "superwhite" color, so bright it almost glows in the dark.
Stereo in it is VERY bass heavy, guess they think we all drive around with the bass pounding away.
For a four cylinder it sure is PEPPY, especially on the highway where we all cruise at 90 mph here in south Florida. Cruises like a six cylinder. Power to spare.
This is not just a Camry problem. It is also occuring in other Toyota and Lexus models with the 5-speed automatic transmission. There is discussion of the problem going on at nearly all of the Edmunds message boards for the various models. There is also a forum that is dedicated to just the hesitation problem in all makes and models that has some good discussion/solutions regarding Toyota/Lexus:
94camryv6 Posts: 4I have a 94 Camry V6 with the same problem. Local mechanic mentioned that it could be the fuel filter. He didn't have time to replace it today. When I have it replaced, I'll let you know if that helps.
A note that when this first started about 8 weeks ago, I thought it was the transmission, I have 157K miles. Then, 2 weeks ago, reverse started to slip very bad, then the overdrive button didn't work when I wanted to use 3rd gear to help slow down. I had a used transmission put in. But the jerking is still there.
Hope I can help.
Hi, I have a 97 Camry and just the other day the check engine light came on. And me not knowing too much about cars didn't want to take any chances so I went straight to a mechanic. After doing a diagnostic they said it was the 02 sensory, so I say go ahead and replace it. After they were done the check engine light wasn't on anymore so I was all happy, and drove the car straight home, about a quarter mile from the mechanic. Then this morning I turn the car on for the first time since I got back from the mechanic and the light turned on again. So besides going back to the mechanic and demanding that something should be done, is there anything else I should do?
I noticed in day one when I picked the car about jerky thing. Immediately, I checked the transmission fluid and it was at correct level.
I mentioned this problem to service guy, he said " wait until 1000 miles over break-in period". Now the car has 20K and it's still jerky.
Brought the car to Toyota dealership twice, nothing they can do about it.
It's design flaw and Toyota could not figure out to fix it. There were several TSB about transmission and none of them could fix the problem. :confuse:
Monday 05/16/05 I purchased a 2003 Camry with 38,000 miles on it from the local FORD dealership here in Selma, Al. I love the car, it drives great, looks good, etc. Wednesday 05/18/05, the check engine light came on. I looked at the owners manual and it suggested that the gas cap may be loose. I checked this, it was not loose. I took the car back to the FORD dealership and of course they act like they have never seen me before, forgot all about my $14,000 purchase.
They say that I must take it to a toyota dealership. The nearest one is 50 miles away in Montgomery, Al. I am getting NO CO-OPERATION from these Goobers. I want to know if anyone else has experienced the Check Engine light problem with their 2003 Camry? Did I buy a :lemon: ?
I took my Camry back to the mechanic, and it turns out that the 02 sensor they installed was bad, and this is a sensor I watched them take out of the package, so I am guessing these things are pretty fragile. I have learned that your best bet is to go to AutoZone and let them to a free electronic diagnostic, and then if there is a problem you can decided what to do from there. And if there isn't just ask them to erase the check engine light, and if it turns on again then go to a mechanic, the dealerships are way too expensive.
siren1 Posts: 1The clicking sound for the turn signals of my 2005 Camry LE has very little volume and can't be heard in traffic with the window open or radio on etc. The dealer has offered to relocate the unit to be closer to the driver to possibly make the sound more audible. He said it would take 2-3 hours to do this . Are there any other solutions to increasing the sound level of the turn signals?
bunny2 Posts: 2I recently purchased a 1999 Toyota Camry LE V6 with 21,000 miles from a private owner. We immediately had the oil changed after we purchased the vehicle. I was surprised when the oil light came on before the next scheduled oil change. Around town the car drove fine. Then, I drove the car approximately 10 hours. Five hours going and five hours returning. I had to add 4 qts of oil in the car. I again took the car into my mechanic, since he checked the car out before I purchased it, and he could not locate any visible signs of an oil leak. Therefore he speculated that something was going on inside the engine. I need help from you as to the exact contents of the letter such as address and or telephone number so that I can get help. Thanking you in advance for your time and effort. How is your car?
Sounds like you could have the dreaded engine sludge problem. Symptoms include what appears to be a loss of oil (it isn't really being lost, it is just turned into a goo that does not circulate), smoke coming out of your exhaust, and eventually the check engine light may come on. Sometimes people can see that the oil is thick, very black, and even chunky on the dipstick. There is a lot of information on the internet about this, including some old archived discussions here at Edmunds. Do an Edmunds search and internet search for "engine sludge" - several other makes have this problem too, like VW.
There are several 1997 - 2002 Toyota and Lexus models affected (including 1999 Camry) that are covered under a free repair policy that is for 8 years from the original purchaes date, unlimited miles. I am pretty sure buyers of used vehicles are covered too, however, to get your engine repaired for free, you are supposed to provide proof of reasonable maintenance -- unless you have the maintenance records of previous owners, i don't know how you would do this. To positively identify sludge, you will need to get someone to pull the valve cover.
jamisont Posts: 4Refilling break fluid is real bad idea.
If break fluid level is low it means couple of bad things, such as leakage or very thin break pad etc so usually technicians at autoshop see low break fluid level, they would also check those parts.
Refilling break fluid would stop them from doing that, it might be just masking the real problem.
This discussion has been closed.


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Black ice Reference Libraries
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2009-07-04 15:43:10
Clear Ice refers to a solid precipitation that forms when air temperature is between 32 degrees and 27 degrees Fahrenheit and there is a presence of super-cooled, large drops of water (from freezing fog). A rapid build up and slow dispersing of latent heat of fusion favors conditions for the formation of the transparent ice. A similar phenomenon occurs when freezing rain or drizzle hit's a...
Word of the Day
- A gift; a largess; a gratuity; a present; a dole.
The word 'donative' comes from a Latin word meaning 'to give'.


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Scenarios of software value: putting software quality in context.
Sheriff, Mohamed and Georgiadou, Elli (2007) Scenarios of software value: putting software quality in context. In: 2007 SQM and INSPIRE Conferences., August 2007, University of Tampere, Finland. (Unpublished)
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Ayla Reynolds' grandfather arrested on criminal threatening charge
Updated On: Jun 05 2013 08:10:07 PM EDT
Ronald Reynolds, grandfather of missing toddler Ayla Reynolds, was arrested last Friday at his home on 83 Mona Road in Portland on the charge of criminal threatening with a dangerous weapon.
Reynolds, 53, displayed a knife in a threatening manner, said Lt. Jim Sweatt of the Portland Police Department. He offered resistance and a Taser was deployed by police.
He is the grandfather of Ayla Reynolds, who was was 20 months old at the time of her disappearance. Her father, Justin DiPietro, reported Ayla missing from his Waterville home on Dec. 17, 2011.
The dispute with Ronald Reynolds involved a family member in the home and was reported at 5:57 p.m., Sweatt said. Reynolds had a cut after being struck by a bat by a family member.
He was later bailed out of the Cumberland County jail, Sweatt said.
Copyright 2013 by WMTW.com All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Antonia Blanc 5 Piece Place Setting
Use code: MC2014
Antonia Dinnerware makes a fashionable, dramatic statement at a formal dining table. These fine bone china pieces feature a luxurious full-coverage platinum accented design. The striking, intricately woven pattern is enhanced by the clean white centers and brings a touch of sophistication to gatherings. Hand wash only. Not microwave safe. Blanc 5 piece place setting includes a 10-3/4 inch dinner plate, 8-1/2 inch salad plate, 6-1/2 inch bread and butter plate, 9-1/4 ounce tea cup and 6 inch saucer.


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CF Industries' Donaldsonville, Louisiana Nitrogen Complex Conducting Precautionary Plant Shutdown In Advance Of Tropical Storm Isaac
CF Industries Holdings, Inc. (NYSE:CF) today reported that its Donaldsonville, Louisiana nitrogen complex has undertaken an orderly shutdown at the facility in advance of Tropical Storm Isaac which is anticipated to impact the Donaldsonville area beginning in the next 12 to 24 hours. The Donaldsonville facility is located on the Mississippi River between New Orleans and Baton Rouge.
"Our immediate concern is the safety and welfare of our employees and neighbors who may be impacted by the storm," said Tony Will, senior vice president, manufacturing and distribution, CF Industries Holdings, Inc. "We are taking the plant down as a precautionary measure as part of routine hurricane procedures. We are in contact with our customers and will let them know when we expect to resume production and deliveries from the facility."
About CF Industries Holdings, Inc.
CF Industries Holdings, Inc., headquartered in Deerfield, Illinois, is the holding company for the operations of CF Industries, Inc. CF Industries is a global leader in manufacturing and distribution of nitrogen and phosphate products, serving both agricultural and industrial customers. CF Industries operates world-class nitrogen manufacturing complexes in the central United States and Canada; conducts phosphate mining and manufacturing operations in Central Florida; and distributes plant nutrients through a system of terminals, warehouses, and associated transportation equipment located primarily in the Midwestern United States. The company also owns 50 percent interests in GrowHow UK Limited, a plant nutrient manufacturer in the United Kingdom; an ammonia facility in The Republic of Trinidad and Tobago; and KEYTRADE AG, a global plant nutrient trading organization headquartered near Zurich, Switzerland. CF Industries routinely posts investor announcements and additional information on the company's website at
www.cfindustries.com and encourages those interested in the company to check there frequently.
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Roshan Bajracharya
Roshan Darshan Bajracharya is the senior economist at World Bank Nepal, based in Kathmandu.
Job Title: Senior Economist, World Bank Nepal
Language: Nepali, English
Martin Rama
Martin's previous assignments include being the Director of the 2013 World Development Report on Job as well as a one-year spell with the Chief Economist office in South Asia region, and from July to ... Show More +
Job Title: Chief Economist
Language: Spanish, English, French, Portuguese
Johannes Zutt
Johannes Zutt is the World Bank Country Director for Bangladesh and Nepal.
Job Title: Country Director for Bangladesh and Nepal
Language: Dutch, English


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March 26, 2014 | Vol.54 N.13
Fact Sheet
Following is a summary of key federal disaster aid programs that can be made available as needed and warranted under President Obama's emergency disaster declaration issued for the State of Washington.
Assistance for the State and Affected Local Governments Can Include as Required:
• FEMA is authorized to provide appropriate assistance for required emergency measures, authorized under Title V of the Stafford Act, to save lives and to protect property and public health and safety, or to lessen or avert the threat of a catastrophe in the designated areas.
• Specifically, FEMA is authorized to provide emergency protective measures (Category B), limited to direct Federal assistance, under the Public Assistance program at 75 percent Federal funding.
FEMA's mission is to support our citizens and first responders to ensure that as a nation we work together to build, sustain, and improve our capability to prepare for, protect against, respond to, recover from, and mitigate all hazards.
Follow FEMA online at http://www.fema.gov/blog, http://www.twitter.com/fema, http://www.facebook.com/fema, and http://www.youtube.com/fema. Also, follow Administrator Craig Fugate's activities at http://www.twitter.com/craigatfema.
The social media links are provided for reference only. FEMA does not endorse any non-government websites, companies or applications.
# # #
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Ahoy!Filmed by testerd. These tags describe this LomoKino movie: kino, lomography, boat, and thailand.
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replicarolex2012 A linha Designer Corpete Pescoço Scalloped-Edge personalizada com um vestido Train Shoulder Tribunal de Justiça (BWD-067) [BWD-067] - $135.99 :


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Honeywell Inc. announced this week it's doubling the refining and casting capacity for high-purity copper and tin at its Spokane Valley production center.
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Man arrested for walking naked in Flagler Beach
Date: September 25, 2012
by: Andrew O'Brien | Associate Editor
(Click "Like" to become a fan of the Palm Coast Observer.)
An Ormond Beach man was arrested Saturday night after a Flagler Beach police officer saw him walking naked on the Flagler Beach boardwalk, according to a report.
Marty R. Parrish, 52, of Ormond Beach, was arrested around 9 p.m. Saturday, Sept. 22, after a Flagler Beach police officer saw him walking on the boardwalk "completely naked wearing nothing besides a hat on his head," the report states.
According to the officer, Parrish was "making no attempt to cover or conceal (himself)."
Parrish was walking directly across from the 7-11, which was open for business. The officer wrote in the report that there were women, children and elderly people in the area.
"He was also adjacent to Fishermen's Net restauarant, where he could be seen from the windows by patrons," the report states.
Although no witnesses offered statements, Parrish was recorded by an in-car camera, which will be submitted as evidence, the report states.
Parrish was transported to the Flagler County Inmate Facility on a charge of indecent exposure and was later released after posting $500 bail.
Currently 1 Response
- 1.
keep the news coming
- Dec
27 Kwanza
12:00 pm
- Dec
31 New Years Party
6:00 am
- Dec
31 New Years Eve Party
2:00 pm
- Jan
24 Waterfront 5K and 10 Mile Run
9:30 am
Gov. Rick Scott makes campaign stop in Palm Coast
Also, DeSantis makes stop in Flagler Beach.
Football teams, cheerleaders 'in the game' at PCUMC
Also, Flagler Sheriff recognizes three exemplary employees.
OUR TOWN: FPC Alumni Weekend set for Aug. 29
Also, FPRA Volusia/Flagler Chapter launches book drive for children; and Florida Ag. Museum receives bequest from former Ag. Commissioner.


text:
DHHS → MeCDC → Division of Public Health Systems → LPH Districts → Cumberland District Overview
Cumberland - District 2
- Covers Cumberland County
- District Characteristics
- 281,674 people (Census 2010) 337.2 persons per square mile (Census 2010 )
- 1 county government: Cumberland County
- 28 municipalities (incorporated local governments) including cities and towns. Several towns or villages are ocean island communities.
- Healthy Maine Partnerships (HMPs)
- The four District HMPs collaborate to assure HMP-funded staff provide a community-based health promotion presence.
- Healthy Portland and Healthy Casco Bay, (Lead agency/fiscal agent: City of Portland Division of Public Health) Healthy Casco Bay has a MOU with the Access Health HMP (Midcoast District) to deliver designated services to Brunswick in the Cumberland District.
- Healthy Rivers and Healthy Lakes Communities Promoting Health, (Lead/fiscal: People's Regional Opportunity Program [PROP], Inc.)
- Maine CDC District Contact
- Becca Matusovich - Cumberland Public Health Liaison
phone: (207) 797-3424
e-mail: firstname.lastname@example.com
- Becca Matusovich - Cumberland Public Health Liaison
- Health Data and Information


text:
"Avid gardener, and I raise poeltry including heritage turkeys and chickens. I have shopped at Sears since childhood"
"I am a country gal who likes the simple things in life. I like the outdoors including gardening and fishing."
"I love turning wrench on my projects - motorcycles and cars mostly. Racing fanatic, performance enthusiat, (Craftsman) brand loyalist."
"I work hard and am loyal to any company that I work for and represent. My humor can be a little dry sometimes, but I always enjoy a good ..."
"Call me Dee, I am about saving money and time, that is why I am here to help you! I'm not into sales, I've got a keen sense of style and ..."
"I have been married to my high school sweetheart almost 28 years. We have 2 grown children, and four grandchildren. I love my family!"
"I am Married have a 20 year old son, I dont work stay home mother. I love to get on computer to play shop your way rewards"
"Professional Financial Member Service Manager; Nationally Published Poet, Author; LGBTQ Gay Community Advocate & Nice Guy."
"Mom to 3; Grew up with Sears (can still remember the dresses my mom got me from Sears); Love Sears and KMart"


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Archive for the 'TV Ratings Reference' Category
March 29th, 2012 at 9:04 am
The TV Fan's Five Stages Of Grief
The signs to look for.[Read-More]
March 16th, 2012 at 4:52 pm
When Will You Know If Your Favorite Show Is Canceled or Renewed?
Here are the dates.[Read-More]
March 10th, 2012 at 8:39 am
Fear the Sun! What Will Daylight Saving Time Do To Your Favorite Show's Ratings?
It burns! (ratings)[Read-More]
February 24th, 2012 at 8:45 am
With No Blockbusters Up For Best Picture, Expect 'Academy Awards' Viewership To Fall; Ratings History + Your Guess For This Year (Poll)
Marvel at past Oscar viewership, and guess this years![Read-More]
February 21st, 2012 at 11:00 am
Numbers 101: What's a TV Rating and Who Is It Dating?
Updated Nielsen TV universe estimates for the 2011-12 season[Read-More]
February 11th, 2012 at 8:33 pm
Historical TV Ratings for the Grammy Awards: 1974-2011
Historical Grammy Awards ratings through 2011.[Read-More]
February 4th, 2012 at 9:06 am
Will 'Super Bowl XLVI' TV Viewership Set Another Record? (Poll+ Ratings History)
What's your guess for viewership for Super Bowl XLVI?[Read-More]
February 2nd, 2012 at 8:55 am
The Program After The 'Super Bowl': How Will 'The Voice' Do? (Poll+Ratings History)
Take a guess![Read-More]


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Simply connect with Facebook and kiss those password blues away,
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MBC3 is the children's entertainment channel. It delivers a programming mix of children's education and entertainment


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Acclaimed singer returning with a bang bang in Brum next January
Jessie J and Waterboys steal shows as events in Longbridge and Moseley wrap up weekend of top music
Dizzee Rascal topped Saturday's bill with former The Voice judge Jesse J headlining on Sunday
Josh Cuthbert answers your questions
Your chance to win tickets to the fantastic Fusion Festival!
Some of the best pop acts will perform at Fusion Festival 2014
Hip-hop duo to perform at Longbridge event alongside Pitbull, Jessie J, Dizzee Rascal, The Wanted, The Vamps, Lawson, Ella Henderson, Union J, Neon Jungle, Becky Hill and Foxes
The singer-songwriter, who plays Birmingham LG Arena in October, tops controversial list compiled by BBC Radio 1Xtra
Singer and former The Voice coach munched on Jamaican browned chicken at the popular restaurant
Wildly popular band The Wanted have been confirmed for this year's Fusion Festival…
Music festival season is on the horizon. Sarah Probert picks the best places to soak up the sights and sounds
Chart-topper added to line-up for Weston Park pop extravaganza
Organisers confirm bill for Cofton Park festival and offer half-price tickets for nearby residents
New stars unveiled for Weston Park music extravaganza
Vicky Jackson to perform at Coombe Abbey after travelling around the world with her stage show
Musicians and celebrities arrive for the Brits at the O2 Arena in London
Star comes to Birmingham on new
Eye catching pictures from events at home and around the world
The popstar's signing completes a change in the presenting line-up which has also seen Holly Willoughby replaced by Big Brother host Emma Willis
JLS, Jessie J, The Wanted, Labrinth and Ne-Yo delight music fans at Cofton Park
Tens of thousands flocked to the first ever Fusion Festival to watch acts including JLS, Amelia Lily and McFly
Headliners Kings of Leon gave a storming performance on the Virgin Media Stage at Weston Park
Save a massive £60 when you buy two tickets to upcoming pop extravaganza headlined by Jessie J, JLS, Ne-Yo and The Wanted
Celebrating 10 years on the pop scene, McFly are practically aging rockers. Singer Danny Jones chats to Tom Pell ahead of the band's appearance at the Midland's Fusion Festival.
Your guide to the V Festival in Staffordshire this weekend. How to get there, camping information and on-site facilities
If you're planning on staying in the area for event featuring stars such as The Wanted and Jessie J, here's some suggestions for accommodation
Taking place in Cofton Park, Birmingham, on August 31 and September 1, the music extravaganza features an amazing line-up of top pop stars
The Black Eyed Peas singer will perform in the city on December 4, in between Manchester and London's O2 during the three dates
Ian Cook helps celebrate the motor industry
Bartley Green's Matt - a dead-ringer for Black Eyed Peas singer Will.i.am, celebrated his achievements with an Indian meal with coach Jessie J.
Is there something happening in your area you would like us to report on?
Tell us about it and, if possible, send us a picture
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Over 66% of our visitors, who view over 4m* page impressions every month, are in the desirable ABC1 socio-economic groups.
To book an advert with the Birmingham Mail team call 0121 234 5000, email firstname.lastname@example.com or visit the Trinity Mirror Midlands website for more information.
The Birmingham Mail is part of Trinity Mirror Midlands, offering you unique access to our audience across the region online and in print.
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Editor, Birmingham MailEditor-in-Chief, Trinity Mirror Midlands
A born and bred Brummie, David was appointed editor of the Birmingham Mail in November 2009.
He has over 30 years experience as a journalist in the West Midlands including editorships on the Coventry Telegraph and Sunday Mercury.


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Item# 1122570
$374.00 $314.16
Item#: 1122570
custom made, allow 9-11 weeks, ships Premier Home Delivery, custom items may not be returned
Product Actions
Different sizes, frame options, paper, canvas, and more
The Details
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Dimensions: 24.25" w x 32.75" h
Item#: 1122570
New York Botanical Garden
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quote:Start raising children the way they were decades ago when this sort of shite didn't occur
quote:A ban on guns is just never going to work in the USA. So start requiring teachers to be trained in the use of firearms and also to carry concealed. As brave as the principle at Sandy Hook was, if she would have come of her office or meeting room blasting away with her Glock 9mm she and many of those innocent children might be alive.
quote:Intruder walks in, teacher grabs the gun in her desk or wherever they would keep such weapons, they shoot at each other, student hit in cross-fire. Then what?
quote:This would be met with extreme opposition by the left, but I see it as the only reasonable solution honestly.
quote:To be a teacher now you have to be combat ready?
quote:Intruder walks in. Teacher screams, students scream, intruder kills all and continues to kill until he kills himself or the police show up. Kinda of like what just happened.
quote:The idea is so impractical that it can't be taken seriously.
quote:The idea is so impractical that it can't be taken seriously. As """impractical""" as armed Commercial Airline Pilots?
quote:Do you really think if an intruder walked in, a teacher would have time to get to her gun wherever it would be? Not trying to pick a fight, just trying to see your point of view. Play the scenario in your head. An intruder walks in and he's going to let the teacher run to her desk, cabinet etc. to go get a gun? You don't think she would have been shot before doing so? The only way I see your plan working is if the teacher literally had a gun on her side in a holster. You really want a teacher walking around a bunch of 6 year olds teaching them to color with a gun at her hip?
quote:As """impractical""" as armed Commercial Airline Pilots?


text:
Welcome to the Muppet Central Forum!
You are viewing our forum as a guest. Join our free community to post topics and start private conversations. Please contact us if you need help with registration or your account login.
Sesame Street Season 45
Sesame Street's 45th season officially begins Monday September 15. After you see the new episodes, post here and let us know your thoughts.
"Muppets Most Wanted" Fan Reactions
After you see "Muppets Most Wanted", read fan reactions and let us know your thoughts on the Muppets eighth theatrical film.
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Lumiere West Newton
- b
- bostonrich1234 Nov 11, 2008 08:04 PM
I honestly feel that it might be, pound for pound,one of the best restaurant in the city. I know, but hear me out...
1. The service and atmosphere is upscale, but not stuffy.
2. There is always ample parking
3. The food is outstanding and extremely seasonal
4. The wine list is ample with some really good finds as well as easy to navigate
5. The menu is extremely reasonable. $40 tasting, $55 with wine
Let me know what you think. I've been 5 times and I am always impressed.


text:
10 Best New Stock Ideas by Steven Cohen
3. Shaw Group (SHAW)
Company Profile: The Shaw Group is a provider of construction and infrastructure services to industries like power generation, processing, chemicals and emergency response.SAC Capital's Investment: Cohen's fund bought 1.2 million shares of Shaw Group in the fourth quarter, which had a market value of $32.5 million as of Dec. 31. Share Price Performance: Shaw Group was a dog in 2011, dropping more than 23%. A rebound may be in the offing, with shares up nearly 9% already this year.
2. Michael Kors Holdings (KORS) Company Profile: Named after its fashion designer founder, Michael Kors designs and sells women's apparel and accessories. The company held its IPO the week before the Christmas holiday. SAC Capital's Investment: Cohen's fund bought 1.3 million shares of Michael Kors in the fourth quarter, which had a market value of $35.2 million as of Dec. 31. Share Price Performance: Since the IPO, shares of Michael Kors are up a whopping 80%. Since the beginning of the year, the stock has climbed almost 60%, likely making this position a big winner for Cohen and SAC Capital.
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Public Health and Environment
Public Health's goal is to protect, promote, and improve the health, environment, and quality of life to the residents of Elbert County. The primary purpose of public health is to assure the conditions in which people can be healthy.
Most of the work of public health agencies is population based--that is, it focuses on improving the health of the entire community.
Public Health Services are available to the entire community and are partly funded by tax dollars. There is a fee with all services but no one is refused due to inability to pay. Elbert County Public Health is devoted to preventative services and education. We are unable to offer emergency or sick care.
For current news and events please go to the "Public Health and Environment News" tab.


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Use code HA9MWXdetails >* To Save 10% on orders $249 or more. Use promotion code HA9MWX during checkout. Discount does not apply to shipping charges, delivery surcharges, duties or customs fees and cannot be combined with any other offer. Promotion cannot be used on previous orders. This promotional offer may be modified or terminated at any time. Offer expires 12/27/2014 at 11:59pm ET.
Bring the Sea to Life!
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I placed the order on a Thursday and it was on my doorstep the following tuesday- WITHOUT rush charges. The banner was vibrant and printed on quality materials. I will be ordering from ya'll again! Thank you!!
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Great mural. Worked perfectly with our theme for Homecoming.
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Q:can I glue on a window.. Is this durable
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A:If you choose the paper mural, you will receive wall paper paste with the product for walls. We do not recommend to glue to windows.
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Middlesex county, nJ, man sentenced to 18 months in prison for attempted escape from hospital while in federal custody
February 22, 2013
TRENTON, N.J. ŌĆō A Middlesex County, N.J., man who was in custody awaiting a hearing for allegedly violating conditions of his federal supervised release was sentenced today to 18 months in prison for attempting to flee from a Trenton hospital, U.S. Attorney Paul J. Fishman announced.
Joseph Vitale, 59, of Milltown, N.J., pleaded guilty on Nov. 8, 2012, before U.S. District Judge Freda L. Wolfson in Trenton federal court to an Information charging him with attempted escape.┬Ā
According to documents filed in this case and statements made in court:
On March 12, 2008, Vitale was convicted in U.S. District Court of bank fraud. He was sentenced to prison and released in April 2009, when he began serving five years of supervised release. In January 2012, Vitale was charged with violating several conditions of his supervised release and was taken into custody by the U.S. MarshalŌĆÖs Service on Feb. 7, 2012. After making an appearance in court, Vitale complained of chest pains and was taken to St. Francis Medical Center in Trenton, where he was placed in the custody of a private security service that has a contract with the U.S. MarshalŌĆÖs Service to provide security for federal prisoners being treated at the hospital. Vitale remained under 24-hour armed guard.
On Feb. 13, 2012, as one of the security guards was adjusting VitaleŌĆÖs leg restraints, Vitale ran out of his room, evaded the two security guards, and ran down the hallway in an attempt to escape. The two security guards ran down the hallway after Vitale and yelled at him to stop. At one point, Vitale screamed, ŌĆ£IŌĆÖm getting the (expletive) out of here.ŌĆØ The two security guards caught up to Vitale and while attempting to subdue him, one of the security guards struck his knees on the floor. Vitale continued to struggle with the security guards and made several attempts to grab one of their guns, but he was unable to remove it from its holster. With the assistance of at least one other individual, the security guards were able to subdue Vitale and handcuff him.
In addition to the prison term, Judge Wolfson sentenced Vitale to three years of supervised release.
U.S. Attorney Fishman credited deputy marshals of the U.S. MarshalŌĆÖs Service, under the direction of U.S. Marshal Juan Mattos Jr., with the investigation leading to todayŌĆÖs sentencing.
The government is represented by Assistant U.S. Attorney Jonathan W. Romankow of the U.S. AttorneyŌĆÖs Office Organized Crime/Gangs Unit.
Defense counsel: David Schafer Esq., Assistant Federal Public Defender, Trenton