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Research Topics
Genomes and Genes
Ku70 Binding Protein-5 (KUB5), a Novel Factor in Nonhomologous End Joining
Principal Investigator: David Boothman
Affiliation: University of Texas Southwestern Medical Center
Country: USA
Abstract: DESCRIPTION (provided by applicant): Alterations in DNA repair play major roles in breast cancer resistance to ionizing radiation (IR) and chemotherapies. Factors operating in both DSB repair and RNA transcription, specifically proteins regulating RNA polymerase (Pol) II, have been suggested, but few reported. When RNA Pol II stalls, or when transcription cannot properly terminate, RNA/DNA hybrids (R-loops) have extended half-lives that result in DNA double strand break (DSB) formation and genetic instability. Using yeast two hybrid analyses, we identified Ku70 binding protein #5 [(Kub5)/Hera], a highly conserved human homolog of yeast rtt103 that terminates RNA transcription via its regulation of RNA Pol II. Stable loss of Kub5/Hera expression, either by heterozygote knockout or knockdown by siRNA/shRNA expression, leads to elevated basal DSBs, ATM activation, foci formation and chromatid aberrations that were abrogated by RNase H forced over- expression, suggesting a role for R-loops in genetic instability. Kub5/Hera knockdown cells were hypersensitive to IR, equivalent to Ku70 deficient cells, and failed to repair DSBs that require DNA end-processing. We hypothesize that KUB5/HERA plays dual roles in the cell to: (i) regulate RNA Pol II to terminate RNA transcription via its interaction with the RNA Pol II CTD domain;and (ii) stimulate NHEJ processing of complex DSBs by Ku70 and Artemis interactions. When its expression is depressed (e.g., one-half via haplo-insufficiency) R-loops form and DSBs are created due to deficient RNA transcription termination. DNA damage is simultaneously amplified by the cell's inability to repair DSBs downstream, leading to IR hypersensitivity. Three Specific Aims are proposed: Aim 1: to perform structure/function analyses of Kub5/Hera focusing on two regions, the RPR and coiled-coil domains, to uncouple transcription termination and DSB repair;Aim 2: to define functions of KUB5- Ku70-Artemis complexes in DSB repair;and Aim 3: to define the role(s) of KUB5/HERA in regulating RNA Pol II function, RNA transcription termination, and spontaneous DSB formation and chromatid aberrations. These studies will allow us to explore the role of KUB5/HERA over-expression in human breast cancer radio-resistance. PUBLIC HEALTH RELEVANCE: Human Ku70 binding protein #5, also known as HERA, (KUB5/HERA) is a new factor involved in the repair of DNA ends with complex damage, such as blunt-end breaks. Elevations of KUB5/HERA in breast and ovarian cancers, and our demonstration that KUB5/HERA is extremely important for drug and radiation resistance, suggests that this protein is a valuable target for future therapies and a 'valuable predictor of response'for therapies. Our recent observation that KUB5/HERA is required for RNA termination allows us to also investigate the interface between DNA repair and regulation of RNA Polymerase II and transcription termination.
Funding Period: ----------------2010 - ---------------2015-
more information: NIH RePORT
Top Publications
Detail Information
- DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosisLong Shan Li
Laboratory of Molecular Stress Responses, Department of Oncology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
J Biol Chem 283:21394-403. 2008..Thus, MMR-dependent intrinsic apoptosis is p53-independent, but stimulated by hMLH1/c-Abl/p73alpha/GADD45alpha retrograde signaling...
- Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effectD Klokov
Radiological Protection Research and Instrumentation Branch, Chalk River Laboratories, Atomic Energy Canada Limited, Chalk River, ON, USA
Oncogene 32:479-90. 2013..Thus, sCLU is a pro-survival bystander factor that abrogates TGFβ1 signaling and most likely promotes wound healing...
- Cytoplasmic TRADD confers a worse prognosis in glioblastomaSharmistha Chakraborty
Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA
Neoplasia 15:888-97. 2013..Thus, our study suggests that increased expression of cytoplasmic TRADD is both an important biomarker and a key driver of NF-κB activation in GBM and supports an oncogenic role for TRADD in GBM...
- Opposing effect of EGFRWT on EGFRvIII-mediated NF-κB activation with RIP1 as a cell death switchVineshkumar Thidil Puliyappadamba
Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Cell Rep 4:764-75. 2013..If EGFRWT is overexpressed with EGFRvIII, the addition of EGF leads to a RIP1 kinase-dependent cell death. The EGFRWT-EGFRvIII-RIP1 interplay may regulate oncogenicity and vulnerability to targeted treatment in GBM. ..
- Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseasesJulio Morales
Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75399
Crit Rev Eukaryot Gene Expr 24:15-28. 2014..The PARP pathway and its inhibition thus offers a number of opportunities for therapeutic intervention in both cancer and other disease states. ..
- Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repairJulio C Morales
Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390 8807, USA, Department of Biological Sciences, Columbia University, New York, NY 10027, USA, Laboratory of Genetics, Salk Institute of Biological Studies, La Jolla, CA 92037, USA, Department of Radiation Oncology, Case Western Reserve University, Cleveland, OH 44106, USA and Department of Experimental Therapeutics, M D Anderson Cancer Center, Houston, TX 77030, USA
Nucleic Acids Res 42:4996-5006. 2014..Artemis re-expression in K-H-deficient cells restored DNA-repair function and resistance to DSB-inducing agents. However, R loops persisted consistent with dual roles of K-H in transcription termination and DSB repair. ..


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Right, after six years I thought they may have bucked up their installers but I was wrong. Last time I installed it, massive issues with the DB. This time, Its the DB again.
Using TMG 2010 on Windows Server 2008 (would use R2 if TMG did not choke on it). Try to install Triton and it assumes that the DB is already installed. It isn't.
After way too long messing about with it, turns out it only detects and uses the 32bit version of SQL Express 2008 R2.
May help someone else getting stupid pointless undocumented errors from the hopeless installer.
Oh and after manually installing 32bit SQL express 2k8 r2 remember to enable tcp/ip comms to it and give it a different port number as TMG takes the default. You'll need to do this for the Web Security component to talk to it as it can't use shared memory.
Then manually build the DB: http://www.websense.com/content/supp...ng.aspx#598745
Who wrote this installer??? yikes, did they work for RIM beforehand.
Last edited by SYNACK; 26th November 2012 at 11:10 AM.
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subset: commoncrawl


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Internal strife turning Lebanon from Syria front to own war-zone
Assassination of top Hezbollah operative in Beirut sparked speculations ranging from sectarian violence to Israeli involvement, but one thing is clear: A Syrian cease-fire won't necessarily lead to one in Lebanon.
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Residents of the Lebanese city of Baalbek, near the Syrian border, were quick to deny Wednesday that locals were involved in the assassination of a senior Hezbollah operative, gunned down in Beirut a day earlier, further demonstrating Lebanon's increasingly precarious situation.
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I made a Burglar Alarm for under 5 bucks, and items I found laying around the house! No soldering required. (soldering optional)
electric motor, juice lids, battery and sugar, you can make your own cotton candy machine
This is a tutorial on how to hack club penguin, using cheat engine. see my other cheat engine tutorial at http://www.metacafe.com/watch/884358/how_to_hack_games_with_cheat_engine_bloons_td_example/
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Turn a sling shot into a deadly spear gun. See how it's made, then watch the gun's destructive power when I test it at the end of the video.
aparently the owner of this once hot website has been busted. this was one of the greatest resourses for black market movies and shows...RIP...i will bring you another movie site i use that even better that this one was stay tuned ~ SYMSYD
Magnetic gloves make a balloon stand into the air and you control the balloon. Take a look, is a great experiment..
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Amazing display of speed and skill! This painting was made in just under 1 minute! Gotta see it to beleive it.


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June 25, 2012
Stacey Dooley investigates the current global financial crisis and its affects on the young in her brand new BBC 3 TV series Coming Here Soon.
Stacey travels to Greece, Ireland and Japan to find out what it's like to be young and caught up in the world's worst financial meltdown in living memory.
In the first episode of the series Stacy visits Greece to see how austerity measures have dramatically affected the lives of young Greeks, leaving many unemployed, angry and all unsure about their futures. In the second episode Stacey heads to Ireland to where she meets a group of young protesters angry at the financial mess they have inherited and in the final episode she travels to Japan where an entire generation have experienced two decades of an economic slump.
In each episode Stacey offers an insight into what could happen in the UK if our debt was to get any worse and how lessons could be learned.
Coming Here Soon starts at 9pm on BBC 3, Tuesday 26 June. Watch the trailer below:
Six Curtis Brown clients for your discovery
Curtis Brown Group Limited. Registered in England and Wales No 00679620. Registered Office 5th Floor, Haymarket House, 28-29 Haymarket, LONDON SW1Y 4SP. Terms & Conditions | Privacy Policy | Disclaimer


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Cable bundling: So, Comcast (CMCSA), a subscriber can get sweet Internet and cable hookups for $99 to $179 a month for 12 months and all he or she has to do is get a landline phone and caller ID service they neither want nor need? Awesome!
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Some carriers are starting to get it, as Verizon now offers a $70 "double play" version of its $90 "Triple Play" that nixes the landline and saves the consumer $240 a year. Granted, Verizon (VZ) hasn't figured out how to incorporate the voice, text and data customers from its mobile plan into an all-in-one deal for multichannel and Internet, but it's taken an important baby step toward value.
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Angry about the latest tax hikes? Each year, thousands of Americans pack their suitcases, rip up their US passports and move permanently overseas to prevent Uncle Sam from taking their money.
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Thos efew countries that have signed the accord with the usa, are the lowest of the sc um on the earth. Selling their own residents for a fistful of dollars. Bunch of cre -tins.a rse lickers. Luckilly usa is now in a downwards flight. And a fast one. Hopefully it will implode soon. No one needs it. And then it will be the open season on all those juda bankers. The preppers and survivalists in teh usa will hunt them down like rats and clean up the mess. There are whole websites dedicated to that hunt in the near future. Can't wait for that to happen. I would love to see them hanging off some tree, all of them.
I am an American living in Germany
1 we pay taxes in DE
2 we are NOT rich
please dont tax us twice!
i cant believe i cant curse you out on here!
Income Tax in the USA is NOT Mandatory! It's voluntary, says IRS! Fill 1040 with all zeros, morons!
citizenship used to give you citizen rights. No longer true. US can detain or kill you without trial
USA should go after all the illegals within, leave us tax paying(to other countries)citizens alone!
The US government is currently trying to force all of the banks around the world to act as US IRS police. So far, several countries have signed up to this program, but China is resisting. If FATCA succeeds, then your suggestion might be limited to Iran and North Korea.
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2008 Jaydee Custom Guitars
Lead Guitars
Tony Iommi
I was first introduced to Tony back in 1970 when working with John Birch, who was a pioneer of custom made pick-ups,
making them in such a way that they were mechanically noiseless.
In those days Tony used a beautiful Gibson cherry red SG special that had
been fitted with some of John's early pick-ups in the stainless steel covers.
It was this guitar that I used as the blueprint for the contours on our own SG.
In the following years Tony and I became good friends as I was able to solve
some of the niggling intonation problems that he had suffered for many years.
He also had some of the early prototype John Birch guitars, such as a 24 fret
Les Paul shape (pictured) and the first 24 fret black SG with crucifix inlays
and stainless steel scratchplate, which he used up until about 1980.
I couldn't make the guitar in John Birches time so I made it at home. It was made on the kitchen table
and was completed in about 2 weeks. The lacquer was still soft when it was taken to the US, and it
was this factor combined with severe changes in temperature and humidity that caused the paint to crack
and flake off, giving the 'Old Boy' the well worn look that it has today. The guitar was not given a proper
unveiling until I had produced the pick-ups that could deliver the sound that Tony was happy with.
The Jaydee 'Old Boy' SG has become one of Tony's favourites and it is still used today.
In 1975 I was asked if I would tour the east coast of the
States with Black Sabbath as a guitar tech for Tony.
I was reluctant at the time but I gave in eventually through
Tony's persistence. It was then that I thought it would be
a good idea to make Tony another guitar to take to the States as a spare, and also to experiment with
The Supernaturals
Custom Specials
Jaydee SG Series
Jaydee Hooligan
Jaydee Explorer
Jaydee Flying Vee
One Off Specials
Mark King
George Anderson
Tony Iommi
Angus Young
Roy Orbison
Lester J Batchelor
Jaymi Millard
Archive pictures
Customer pictures
Construction pictures
Bass Price List
Guitar Price List
Repair service


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Reviewed Bacon-Wrapped Double Pork Meatloaf
Jan 11, 2012 in Food Network Community Toolbox on FoodNetwork.com
"Absolutely LOVE this meal! My husband usually hates meatloaf, but he loved it and actually had two servings! Used sweet Italian sausage instead of bratwurst and used Ritz crackers instead of Saltines. Definitely will be making this again....awesome, awesome, awesome! """


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The city of Crest Hill is located in the southwest suburbs of Chicago in Will County, IL. This family-friendly community is situated near Lockport and Joliet, and is just a short commute from Downtown Chicago. Will County is one of the fastest growing counties in the Chicagoland area, and Crest Hill is a thriving community. According to statistics from the U.S. Census Bureau, Crest Hill has experienced a growing population from 10,900 residents in 2000 to nearly 21,000 people today. Individuals looking for Crest Hill apartments for rent will enjoy this prosperous suburb in the Land of Lincoln.
People looking to move to Crest Hill should consider the high average commute time for residents, which is 32 minutes. However, the cost of living is 3 percent lower than the national average.
Many residents in Crest Hill apartments and homes commute to the city of Joliet or Howntown Chicago for employment; however, there are many opportunities for employment throughout Will County. Some of the top employers include Provena St. Joseph Medical Center, Silver Cross Hospital, Hollywood Casio, RR Donnelley, Harrah's Casino and Caterpillar Inc.
Residents in the area have access to many entertainment and recreation options throughout the region. During the fall season, many people take advantage of Siegel's Cottonwood Farm, a large pumpkin patch that features a massive corn maze intricately designed. Past designs have been the Chicago Blackhawk and Bulls symbols, a pirate skull and politically-themed pictures during election years.
More adventurous residents head to the top rated haunted house in Illinois, and one of the top 25 haunted houses in America: Statesville Haunted Prison.
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- Notes: With parking and corner light holes
- Replaces OE Number: 55000682
- Replaces Partslink Number: CH2513108
- Warranty: 1-year, unlimited-mileage warranty
Product reviews
rebuild by foreverjeep, September 21, 2012
|Ease of Use/Installation:
|Overall Rating:
Got everything I ordered and its all good stuff. I think I can keep this vehicle forever now.


text:
|Name: _________________________
|Period: ___________________
This quiz consists of 5 multiple choice and 5 short answer questions through Chapter 8, Shadow Warriors.
Multiple Choice Questions
1. Who meets Rashid and Haroun at the railway station?
(a) Twin teachers.
(b) Two politicos.
(c) Two children.
(d) Two firemen.
2. Why is the story Haroun dreams strange?
(a) Because Iff poisoned the story.
(b) Because when he woke up he was upside down.
(c) Because the story was told backwards.
(d) Because the water he drank was polluted.
3. What is Moody Land?
(a) A country that changes depending upon the mood of its residents.
(b) A school that teaches the magic of Moody.
(c) An underwater world where everyone is sad and blue.
(d) A theme park full of sad mascots and visitors.
4. How do the bus drivers tease the passengers wanting to get on the buses?
(a) They drive very slowly around the depot.
(b) They open their doors and then shut them.
(c) They turn on and off their engines.
(d) They walk around pretending to chat with people.
5. How does Blabbermouth treat Haroun when they first meet?
(a) Friendly.
(b) Hostility .
(c) Blabbermouth and Haroun never meet.
(d) Neutrally.
Short Answer Questions
1. What happens when Haroun drinks the story water Iff gives him?
2. What happens to Rashid at the end of Chapter 1?
3. What happens to the water the closer Haroun gets to Chup territory?
4. How long ago did a bus plunge into the gully?
5. Who is also known as the "Shah of Blah"?
This section contains 276 words
(approx. 1 page at 300 words per page)


text:
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Reviewed Mongolian Beef
Dec 10, 2011 in Food Network Community Toolbox on FoodNetwork.com
"This Mongolian Beef is the best that I've ever had!! I am so happy to see the recipe here. I've tried other places since then, and there's just nothing like Benny's. I saved the show on my DVR so that I can watch it while I try to recreate the dish.
I constantly wish that I was still in Alaska to get a plate (minus the snow!!)...."
Saved Recipe Savory Mushroom, Spinach & Cheese Crepes by **Tinkerbell**
Apr 5, 2011 on Food.com
Saved Recipe Candy Apple Jelly by Karen From Colorado
Aug 24, 2010 on Food.com


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MOVIEmeterSEE RANK
Up 18,244 this week
The Bad Man (1941)
- Comedy | Western - 28 March 1941 (USA)
Lopez is a bandit who has stolen the herd at Gil's ranch, so Hardy is about to foreclose. But Lucia has come back from New York and Gil is happy until he meets her husband, Morgan. Saying ... See full summary »
Director:Richard Thorpe
Writers:Porter Emerson Browne (play), Wells Root (screenplay)
Stars:Wallace Beery, Lionel Barrymore, Laraine Day | See full cast and crew »


text:
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North Korea threatens US over Sony
North Korea threatens unspecified attacks on the US as it escalates a war of words over the Sony Pictures cyber-attacks.
China investigates ex-leader's aide
China launches an investigation into former President Hu Jintao's top aide, state media report, after he is accused of "disciplinary violations".
Pope Francis deplores Vatican 'ills'
The Pope tells cardinals there is a need to purge "spiritual Alzheimer's" and "the terrorism of gossip" from the Vatican.
Essebsi wins Tunisia president vote
Beji Caid Essebsi is confirmed as winner of Tunisia's first free presidential poll, but critics say this marks the return of the old regime.
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Congestion and a collision are causing slow traffic at 9:20 a.m. Tuesday on Johnston Road in southern Mecklenburg County.
The collision is at Johnston Road and Ballantyne Commons Parkway, and it is causing moderate delays.
Another trouble spot is the Cotswold area, with Charlotte-Mecklenburg police reporting that a pedestrian was struck in the area near Sharon Amity and Randolph roads.
Here is the 9:20 a.m. update:
I-77 southbound, Lake Norman area ... Congestion; traffic moving 20-30 mph from Brawley School Road (Exit 35) down to Gilead Road (Exit 23).
Sugar Creek Road at North Davidson Street ... Earlier collision with injuries being cleared; minor delays.
Beatties Ford Road near I-85 ... Collision; minor delays.
Harrisburg Road near I-485 ... Collision with injuries; moderate delays.
Johnston Road ... Congestion and a wreck with injuries at Ballantyne Commons Parkway; traffic moving 15-25 mph northbound from the state line to I-485.
Providence Road inbound ... Congestion; traffic moving 20-25 mph from the Arboretum area to Wendover Road.
I-77 northbound, south Charlotte ... Congestion; traffic moving 25-35 mph from Carowinds Boulevard up to Clanton Road.
Billy Graham Parkway ... Congestion; traffic moving 20-25 mph between West Boulevard and I-85.
Karendale Road at Tuckaseegee Road ... Collision with injuries; minor delays.
Shopton Road at New Fashion Way ... Collision; minor delays.
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Portugal is likely to become the sixth European nation—after Belgium, Norway, Sweden, Spain and the Netherlands—to legalize gay marriage. The Portuguese government has proposed to change the country's official definition of marriage to include same-sex unions. —KA
AP via Google News:
The law is almost certain to pass, as the center-left Socialist government has the support of all left-of-center parties, who together have a majority in Parliament. Right-of-center parties oppose the measure.
The proposal changes Portuguese law to remove references to marriage being between two people of different sexes, Cabinet Minister Pedro Silva Pereira told a news conference Thursday, adding the government will send its proposal to lawmakers for a debate, probably in January.
If approved by Parliament, the proposed law goes to Portugal's conservative President Anibal Cavaco Silva, who can ratify or veto it. A veto can be overturned by Parliament.
If there is no presidential veto, the first gay marriage ceremonies could take place in April — a month before Pope Benedict XVI is due on a four-day official visit.
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text:
Truthfully, I am feeling a tad impatient, but I am also trying to be a good sport because I know this kind of thing happens to everyone. The man who is a contractor is asked at a holiday party what he would do to make the host's living room just a bit larger. A massage therapist hears the same joke every time: "Wow, your husband must love being married to you!" The dentist is asked how she can stand to "look at all those people's teeth every day!" The thing is I am used to fielding questions—from parents and teachers alike—in a more typical manner: through emails or phone, or at meetings in conference rooms. Sometimes I am even stopped in the halls at the schools I work in so I can give my opinion as to whether or not a certain child's behavior in the classroom is "typical of a gifted kid."
On this occasion, though, the reason I am biding my time, hoping that the sales lady at Lens Crafters will soon be available, is because the lady talking to (read: at) my wife and I has entered that stage of the conversation that is commonly joked about among those in education: Everyone thinks their child is gifted.
Of course, I am being a bit facetious. For all I know, this lady's son really is gifted but I cannot judge based solely on the evidence she is offering. She insists her son must be so because as, a kindergartner, he is already reading at the second grade level.
Please understand: this reading level is impressive, sure, and like the school curriculum for any learner, this child's advanced abilities in this area should require his school teacher to adjust her lessons accordingly. However, that claim alone is not enough to certify this young man as gifted.
Although I will not get into this exchange of ideas now—seated as we are among others who are waiting their turn to have lenses ground or frames adjusted—I have had this conversation, or similar ones, many times over. Once we finally get there, at the heart of it all, will lie two central debate points. One is the age old question of Nature versus Nurture. The other will focus on how we ultimately define and assess the quality of "gifted-ness."
Um, not so fast. Perhaps it's true that he is gifted, but it is not necessarily true merely because those examples could be offered.
It is possible that this lady's young child is reading above grade level because he comes from a household that is rich with stimulation (ahem, Nurture). His parents, and in particular his mother who is an English teacher, likely read to him every night. They engage him in conversation and use wide-ranging vocabulary to express themselves. They encourage and foster his reading skills when, say, they go the grocery store and ask his help as they read the signs above each aisle trying to find the ketchup (catsup?). More than likely, this child even sees reading modeled as a habit at home. So when his Fountas and Pinnell pre-test places him at Level G—while another child whose home is a bit less stimulating lands on Level B—it is tempting to look for the gifted traits right away.
And yet if the parents of both children—the lower and higher enrichment households—could somehow look ahead into their child's third or fourth grade school year, they might be surprised to find that each child is reading now at the same level. Why would this happen? Simply put, the enriched child's household gave him a leg up on his peers, but true "giftedness," as we might typically define it in most schools, was never really at play.
And so you see why the second debate point arises: This begs the definition of what true "giftedness" really is.
That conversation is a hard one to navigate and it's made no less difficult when you find yourself in a strip mall store with a person you have met only fifteen minutes ago. Another reason why I have decided to let this mother speak her mind as I, mostly, nod my head.
Granted, Gardner never wrote actually wrote about the nature of being "gifted" in the way that this mother is discussing that word with me. And yet, his theory single-handedly created a new way to have a conversation about any individual's strengths and weaknesses, both in and out of school. It allowed teachers and parents alike to see and identify the real "gifts" that were at play when, say, a high school sophomore could completely deconstruct and then reassemble a car's V-8 engine—even as he failed his English end-of-grade test by just a few points.
Alas, … I would eventually have to tell this very animated woman before me that—no matter how much I personally love his theory's inclusiveness—Gardner's particular notion of intelligence (and what that might imply for defining "giftedness," and offering subsequent "gifted services") is a little less than practical in most schools. The truth is that it is easier to identify students as traditionally "gifted" if we fall back on the more standard, nationally norm-referenced assessments, like,… yes, an IQ test.
You're clever, dear Reader. You can see where this is going and, now, why I have avoided engaging in this dialogue: at this point in the conversation, the same central two debate points we might have been plowing through would come full circle.
Did the enriched verbal household give that child an advantage in his early gifted identification? Is that why it appears that the other child had "caught up" by fourth grade? Or perhaps that young child truly is gifted. How then, some would argue, do we define that other fourth grader's "gifts?" It's easy for this to become a circular conversation, and you start to see why a lot of school districts don't even bother with full-bore "gifted identification" until the third grade year.
I see that, finally, a store employee has been freed up, and so now it is our turn to be fitted.
"Yeah," I say, standing up, "I hear you. That's a tough call." I'm hedging my bets as I wrap up the conversation because, as I've told you, I don't know her child at all—especially to intuit solely by this conversation if he's gifted or not. "I think you should talk to the teacher some more. You can always ask for him to be screened whenever you want. And keep doing what you're doing at home!"
We shake hands. It occurs to me that Howard Gardner might tell her not to worry so much about her kindergartener, to instead look at all the ways her child is "gifted"... and talented.
There's certainly merit in that.


text:
Pink Sugar Sensual Perfume
By Aquolina for Women
Pink Sugar Sensual Perfume by Aquolina, Launched in 2009 this is a sweet and seductive fragrance for women and an oriental vanilla version of the original . Top notes are black currant, tangerine and bergamot, heart notes are orange blossom, light nuances of pink jasmine petals and tiare flowers. Base notes are alluring and seduce with the sweetness of vanilla, black sugar and woody accords of sandalwood. All products are original, authentic name brands. We do not sell knockoffs or imitations. ... Read More
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Item #482197
Testers are even more discounted than the fancy boxed versions and are great if you don't have a need for the fancy packaging... Read more Testers are 100% authentic, fresh and completely full just like the original fragrance, however they are meant for the counter in a department store. Testers often come in a plain white box but sometimes they do not have a cap or box.The savings on the packaging means you save even more!
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All as promised, delivered safely and quickly! Thanks!
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REVIEW SNAPSHOT®by PowerReviews
- Great smell (24)
- Sensual (21)
- Great value (16)
- Draws compliments (13)
- Sexy (13)
- Doesn't hold (6)
Best Uses
- Anytime (21)
- Special occasions (10)
- Daily use (9)
- Evening (9)
- Signature fragrance (4)
- Reviewer Profile:
- Adventurous style (10), Classic style (9), Natural style (7)
- Fragrance Type:
- Oriental/spicy (11), Citrus/fruity (10), Woody/earthy (7), Powdery (6), Floral (5)
Most Liked Positive Review
Sweet and sassy, sexy and bold. It it not too strong right off the bat. I really love this fragrance, however it doesn't hold very long. I don't usually go for the...Read complete review
Sweet and sassy, sexy and bold. It it not too strong right off the bat. I really love this fragrance, however it doesn't hold very long. I don't usually go for the sweet ones, but this is delicious!
Most Liked Negative Review
Sugary and vanilla, young fragrance
I enjoy this fragrance, its a little too musky for me, though every time I sprayed it before I bought it, I loved it, but when I received it, I thought it...Read complete review
I enjoy this fragrance, its a little too musky for me, though every time I sprayed it before I bought it, I loved it, but when I received it, I thought it smelt a whole lot like a bathroom deodorizer. Anyway, I determined to like it, and now think it smells like gummy bears and rich vanilla at other times. It had to grow on me. I don't think its very sensual though. That's just me. It's not something I can't live without.
its definitely a younger girl's fragrance and too potent to wear out, with that being said, it also does not have good sillage or lasting power either though. i think i might be embarrassed to wear this in the office, maybe for more casual get togethers though. it smells like something that would be at a *young* teenagers store.
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Comments about Aquolina Pink Sugar Sensual Perfume:
I just want to congratulate Fragrance X for such great perfumes. I am really enjoying my Pink Sugar Sensual. It makes me feel sexy everyday..My husband loves the perfume.. I think it is graet
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Best Uses
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Comments about Aquolina Pink Sugar Sensual Perfume:
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- Sensual
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Best Uses
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It smells great can't wait to wear it tomorrow. I bought the tester. It was packaged great and was full. My order arrived within 3 business days.
- Fragrance Type:
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- Draws Compliments
- Great Smell
- Great Value
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- Doesn't Hold
Best Uses
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- Signature Fragrance
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Great perfume for everyday use. It is definitely a signature smell and people will ask you what smell you have on, because it is so special (in a positieve way). Unfortunately it does not hold very long, but other than that it is amazing. I would definitely recommend it to my friends. In fact, a friend even bought this perfume because she liked it so much.
- Fragrance Type:
- Herbal, Oriental/Spicy, Woody/Earthy
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text:
Euro stable versus dollar on weak US trade data
In late London trade, the euro traded at 1.2522 dollars from 1.2505 dollars late in New York New York, state, United States
New York, Middle Atlantic state of the United States. It is bordered by Vermont, Massachusetts, Connecticut, and the Atlantic Ocean (E), New Jersey and Pennsylvania (S), Lakes Erie and Ontario and the Canadian province of on Wednesday.
French President Nicolas Sarkozy said ahead of a weekend summit on the global financial crisis that the dollar can no longer claim to be the sole world currency.
"I leave for Washington tomorrow to explain that the dollar, which at the end of World War II End of World War II can refer to:
- End of World War II in Europe
- End of World War II in Asia
The euro's rebound followed a report that while the US trade deficit narrowed in September, imports showed a record slide, with exports also down sharply -- indications that US economic momentum was running out of steam.
The euro rose to 120.07 yen from Wednesday's level of 118.19, but it was kept in check by more gloomy indicators of recession in Europe.
Official figures showed on Thursday that eurozone Eurozone
same as Euroland
Eurozone n → eurozona, zona euro
Eurozone n → zona euro kingpin Germany plunged into recession for the first time in five years as the global financial crisis hammered the world's third biggest economy.
It was the first major economy to confirm that a long-feared recession had arrived, with France, Italy and the entire 15-nation eurozone expected to follow on Friday.
Dealers were meanwhile awaiting to hear speeches from the head of the European Central Bank European Central Bank (ECB)
Bank created to monitor the monetary policy of the countries that have converted to the Euro from their local currencies. The original 11 countries are: Austria, Belgium, Finland, France, Germany, Ireland, Italy, Luxembourg, the Netherlands, Portugal, , Jean-Claude Trichet Jean-Claude Trichet (born December 20, 1942) is a banker was born in Lyon, France, trained as an engineer at the École nationale supérieure des Mines de Nancy and later as a civil servant at the Institut d'etudes politiques de Paris (best known as Sciences Po) and the Ecole and other bank chiefs at a conference of the European Central Bank on Thursday.
"The risk... in our view is that ECB See electronic code book. speakers sound more dovish, especially given the recent weakness in data, which would weigh further upon the euro," said David Woo at Barclays Capital Barclays Capital is the investment banking division of Barclays plc. It is a primary dealer in U.S. Treasury securities and various European Government bonds.
Barclays Capital is led by CEO Robert (Bob) Diamond, an American who had been vice-chairman of Credit Suisse First .
After the ECB had last week slashed eurozone interest rates by half a percentage point, Trichet suggested at a press conference that more reductions could be on the way.
Against the Japanese currency meanwhile, the dollar climbed to 95.89 yen from a level of 94.61 yen reached on Wednesday.
The yen gave back some of the previous day's strong gains that were sparked by news Washington is scrapping a plan to buy up toxic mortgage debt.
Market watchers said the yen could turn higher again because of falling stock markets and growing worries about the financial crisis. The yen tends to benefit from market turmoil because it is often sold to fund risky bets, and is seen as a relatively safe haven 1. Designated area(s) to which noncombatants of the United States Government's responsibility and commercial vehicles and materiel may be evacuated during a domestic or other valid emergency.
2. investment.
The British pound meanwhile suffered more against the euro, hitting 1.1824 euros, a low point not seen since 1992, according to Lee Hardman of Bank of Tokyo-Mitsubishi. Sterling sank to a six-year low of 1.4807 dollars.
The euro changed hands at 1.2522 dollars against the level of 1.2505 dollars reached late on Wednesday, at 120.07 yen (118.19), 0.8458 pounds (0.8350) and 1.5016 Swiss francs (1.4825).
The dollar stood at 95.89 yen (94.61) and 1.1991 Swiss francs (1.1864).
The pound was at 1.4804 dollars (1.4955).
On the London Bullion Market The London bullion market, is entirely different from, but often confused with the London Metal Exchange. Only base metals are traded at the London Metal Exchange (LME), while gold and silver are traded by members of the London Bullion Market Association (LBMA), loosely overseen by , the price of gold fell to 713.50 dollars an ounce from 724.75 dollars late on Wednesday.
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Nikita Denise is a Porn Star from Czech Republic. She was born in Brno on July 25, 1976. Nina Ferrari is a Porn Star from United States. She was born on January 13, 1975.Incoming search terms:
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(Graphic: Charles Schwab)
According to a new study from Schwab, seven in 10 affluent investors feel today's financial markets are too complicated to navigate without an advisor. One-third of study participants also say their desire for investment advice has increased in the past year, and three-quarters say they are most confident making investment decisions when they collaborate with their investment professional; just one-third say they feel that same level of confidence when making investment decisions by themselves.
Advice and the Affluent Investor: A Study of Attitudes and Behavior by Charles Schwab (AAIS) surveyed more than 1,000 affluent Americans who receive some form of professional financial advice. Seventy percent of those surveyed work with a single advisor, and while on average their advisor handles 43 percent of their assets, nine in 10 want to work with an advisor who looks at their entire financial picture.
Trust and transparency are cornerstones of these relationships. Those surveyed trust individuals in the financial services industry (72 percent) more than financial services companies (42 percent), and 10 percent trust no one; an overwhelming majority want transparency around how their advisor is compensated for the advice they are providing (85 percent).
"Regardless of how much and how deep the advice, today's affluent investors have one thing in common: they want a trusted expert on their side looking at the big picture on their behalf," says Bernie Clark, executive vice president and head of Schwab Advisor Services.As of May 31, Schwab's suite of advice offerings for retail investors has grown to $139 billion assets under management from $114 billion the prior year. Additionally, as of March 31, Schwab custodied $895 billion in client assets for more than 7,000 independent Registered Investment Advisors (RIAs). The study found that very few (11 percent) affluent investors see themselves as advanced investors; most label themselves as an intermediate (68 percent) and one in five (21 percent) describe themselves having beginner skills. Fully half of respondents see investing as a chore, and not an activity they particularly love or hate. Despite these tepid feelings, four in ten (41 percent) say they are much more involved in their investments in 2013 than they were in 2012.
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text: Insight Genetics Culture Insight is proud of its culture, which focuses on providing a meaningful and challenging work environment where individuals are part of a team and are recognized for their creativity and ability to meet company goals. We offer a competitive salary, as well as medical and life insurance. Scientific Environment Insight Genetics is a technology- and people-driven company that prides itself on its scientific excellence. We seek to hire exceptional scientists who thrive in collaborative, team-oriented research programs. If you are a forward thinking, productive scientist with an interest in improving cancer patient care through the creation and development of more effective diagnostic assays, please apply for a position with us. Current Openings: Research Associate I Organizes and performs a variety of molecular laboratory procedures using established methods and techniques. Capable of performing analysis and interpretation of data for presentation to scientific staff. Has knowledge of commonly used concepts, practices, and procedures within molecular diagnostics. View the full job description here. Clinical Laboratory Molecular Biologist The clinical laboratory molecular biologist position performs all aspects of pre-analytic, analytic, and post-analytic activities of the laboratory workflow appropriate for the Clinical Laboratory sections. View the full job description here. We look forward to hearing more about your background and interest in joining the Insight Genetics team. Please use the form below to contact us. NAME: EMAIL: PHONE: UPLOAD CV: INQUIRY:


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A person can't just drive around the North Slope, visit the locals, stop in at a burger joint. There are no locals, no burger joints, no houses, no cities, no churches. The gateway to the oil fields is the town of Deadhorse, where the airport is, and where security restricts passage to anyone but workers who fly in and get bused to camps for two-week hitches.
It took nearly a year for me to gain access to the Slope. The corporate giants who control the fields—BP, ConocoPhillips, ExxonMobil—have little to gain from public scrutiny. Rarely do stories of Alaska's oil emerge unless there is a freak accident to talk about—the odd spill, usually set against a snowy backdrop featuring a winsome caribou looking dismayed about the greedy nature of the human race. But Pioneer Natural Resources—the company that built the island, where TooDogs is in charge of the rig and Kung Fu plays the fiddle and Turtle fake-hates Jason for lying to him about being married to a stripper named Onyx—was willing to allow me in. Pioneer is the first independent operator to produce oil on the Slope, a market cornered by the three majors for its entire history. In many ways, it represents a glimmer of hope. Everyone knows the oil up here is running out; production is declining 6 percent a year, down from an all-time high of 2 million barrels a day in 1988 to 700,000 today. But everyone also knows the oil isn't really running out—it's just a lot harder to get to. It is a common story in the saga of natural resources, whether you are talking coal or gas or oil: The big companies suck out the easy, vast reservoirs, and then in come the little companies nimble enough to pick away at the leftovers.
The ongoing debate over whether or not we should be drilling for oil in Alaska—onward to ANWR to the east—typically leaves out one factor: We are drilling for oil in Alaska, every hour of every day for the past thirty years, drilling in some of the most extreme conditions on earth, where the windchill can easily reach minus ninety-eight degrees, so cold that you have to leave your pickup running twenty-four hours a day or you'll never get it started again, where it is pitch dark for nearly two months each winter, where people live without families, without homes, without access to so much of what most of us think of when we think of what it means to be human.
Who are these people, and how do they get the oil out of the ground? It seems, on its face, an embarrassingly simple question, and maybe that's the point. Crude. Petroleum. We process it into gasoline, asphalt, plastic, fertilizer. We fill up our cars with it, drive on roads made of it. We use it to make all those soda bottles and all those Baggies holding our lunches, the foam in our mattresses, the padding in our running shoes. The vegetables we eat are fed with and protected from bugs by it. We travel because of it, drink out of it, sleep on it, wear it, eat it, whine about how much it costs, argue about it, hate needing it, love it, kill for it. It is our most ubiquitous natural resource, the juice that made the past century possible. How we get it in the first place would seem to be a fundamental building block in our understanding of what it means to be a modern human. And yet here is an industry and a culture that is as alien to most of us as the moon.
I visited the North Slope twice, once in summer and then again in February, when I settled in for a two-week hitch. The temperature, on the day I landed in Deadhorse in February, was forty-five degrees below zero. I worried about what that might feel like, wondered if the clothing I'd been provided—thick overalls, massive parka, enormous gloves and boots—would really do the trick. I geared up and felt like an astronaut. I bounced out of the plane, squinted as if preparing for a punch. I felt nothing of the sort. For the first three or four seconds, cold is just…cold. Nothing spectacular at all. Then my glasses seemed to freeze to my face, and I took a breath and felt a sting in my lungs that might have been instant ice but probably wasn't. Within minutes, my cheeks, chin, and nose began to ache, first the skin and then…muscle? I had no other way of understanding that weird sort of ache. Soon I learned to aim the hood of my parka, lean my head so the fur trim would catch the wind and steer it away. Every little bit helped. I started admiring animals with very bushy fur.
Deadhorse is a place that greets you with the emblematic architecture of the Slope. Nothing is lovely, nothing is charming, nothing is intended for anything other than hard use. Modular corrugated-steel Conex boxes serve as office buildings, machine shops, a hotel, and a general store decorated outside with a cartoon drawing of a dying horse with its tongue hanging out.
The two-hour bus ride to Oooguruk, over the ice roads, was a visit to a postapocalyptic world, an endless industrial landscape without the humanizing effect of pedestrians. We saw a musk ox. The heater on the bus barely worked, and so the guys huddled into their parkas and shivered but did not complain. Oooguruk is six miles off the coast, and so by the time we drove into camp, there were no signs of other rigs, other camps. No neighbors at all.


text:
Porsche automobiles--History
From Library of Congress Subject Headings
Porsche automobiles--History
- http://id.loc.gov/authorities/subjects/sh2010107714
- info:lc/authorities/sh2010107714
- http://id.loc.gov/authorities/sh2010107714#concept
Instance Of
Scheme Membership(s)
Collection Membership(s)
- found: Work cat.: Porsche 356 and RS Spyders, 1991
Editorial Notes
- [Record generated for validation purposes.]
Change Notes
- 2010-05-18: new
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New liquidity rules for banks to start taking effect from Jan 2015
Published on Jun 24, 2014 8:39 PM
Tighter rules aimed at bolstering the cash buffer banks must hold in case of emergency start will start taking effect in January, Trade and Industry Minister Lim Hng Kiang said on Tuesday.
The new regulations centre around what is called a liquidity coverage ratio, a standard introduced under Basel III, the name given to wide-ranging reforms being implemented for the global banking industry.
It seeks to ensure that banks hold sufficient high-quality liquid assets to match their total net cash outflows over a 30-day period.
The Monetary Authority of Singapore consulted the public and the banking industry on these changes last August and took their feedback into account when finalising the new rules, Mr Lim said at an Association of Banks in Singapore dinner.
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- Running
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About This Activity
Enjoy a run under the full moon. This social event is tons of FUN! Great tshirts to the 1st 200 runners and lots of applause (no awards) at the finish.
Event schedule and times
Please park in the C-11 lot west of the Rec. Pick up your shirt from 9-9:30 pm or register outside the Rec Center at the south side of the Leisure Pool entrance. Everyone will be given 2 glow stick wrist bands--please feel free to wear other iridescent objects. You will be running on cinder track and roads. Walkers may do as many laps of the 1 mile track as desired. Only runners allowed on the 5K course through campus.
Organizer Info
Texas Tech Recreational Sports
Photos1 of 1
Map & Direction
Thursday, June 12, 2014
Student Rec Center 3219 Main Street Texas Tech University Lubbock, TX 79409Get Directions


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Welcome International Customers
We're excited to share our jewelry collection with you!
Just choose your country and currency to personalize your shopping experience.
We're excited to share our jewelry collection with you!
Just choose your country and currency to personalize your shopping experience.
14kt Yellow Gold Textured Bangle Bracelet
Super Deal from: $395.00
18.25 ct. t.w. Blue and London Blue Topaz Bracelet in Sterling Silver
Super Deal from: $265.00
Sterling Silver Stackable Bangle Bracelet
Super Deal from: $65.00
14kt Rose Gold Over Sterling Silver Stackable Bangle Bracelet
Super Deal from: $65.00
Item#: 821515
This bracelet is inspired by a kaleidoscope – and just as charming. Features multi-shapes of 15.25 ct. t.w. multi-stones, including garnet, blue topaz, citrine, peridot and amethyst. Lobster clasp, 18kt yellow gold over sterling silver bracelet.
Due to the incredible value on your Super Deal selection, no additional discounts apply.
Details Gift
Box Our 100%
3/8 inch
18kt 18KT: Karat (abbreviated kt or K) is a unit that indicates the purity of gold in the metal. 18kt is 75% gold. In Europe, 18K yellow gold is most favored and used in jewelry. Gold Over Sterling STERLING SILVER: Also known as "Standard Silver," sterling silver is silver alloyed with other metals to increase the hardness and durability. Generally, sterling is 92.5% silver and 7.5% other metals. Some sterling silver jewelry is plated with 14kt-18kt gold and referred to as "vermeil," or "gold over sterling." Silver
Polished POLISHED: A buffed-out finish used to produce a mirror-like shine.
Lobster LOBSTER CLASP: named after the pinching style of the hook, this clasp is often shaped like a lobster's claw. Use your finger to work the lever to open the clasp.
Stone 1:
Topaz TOPAZ: Available in a stunning selection of shades, the topaz's sky blue hue is one of the most popular colors for jewelry designs. Once thought to offer protection, today topaz is favored for its durability and affordability. Yellow topaz is the birthstone for November while blue topaz is for December. (Color: Blue, Quantity: 4, Shape & Cutting Style: Multiple, Weight: 5.25 ct. t.w., Size: 6-7 mm)
Stone 2:
Citrine CITRINE: A member of the quartz family, citrine symbolizes cheerfulness and prosperity. Its name is derived from the French word citron meaning lemon. This sunny stone comes in colors from lemon yellow to amber brown, with its coloring agent attributed to iron. Citrine is the birthstone for November. (Color: Yellow, Quantity: 4, Shape & Cutting Style: Multiple, Weight: 3.30 ct. t.w., Size: 7-7x5 mm)
Stone 3:
Peridot PERIDOT: the birthstone of the month of August, peridot is only found in one color: green. Historians are now convinced that some, if not all, of the emeralds that Cleopatra was famous for wearing were not actually emeralds but deep green peridot stones from Egypt. (Color: Green, Quantity: 2, Shape & Cutting Style: Multiple, Weight: 2.20 ct. t.w., Size: 6-7 mm)
Stone 4:
Amethyst AMETHYST: A natural variety of quartz, amethyst ranges in color from deep purple to pale lavender, and even to warm greens. Amethyst has been used during meditation to provide a sense of spiritual balance. Amethyst is the birthstone of February. (Color: Purple, Quantity: 2, Shape & Cutting Style: Multiple, Weight: 2.20 ct. t.w., Size: 7 mm)
Stone 5:
Garnet GARNET: the birthstone of January. One glance at the deep red seeds nestled inside of a pomegranate explains why the word "garnet" comes from the Latin word "granatus," meaning "grain" or "seed." This name was given to the garnet because of its close resemblance to the succulent seed. (Color: Burgundy, Quantity: 2, Shape & Cutting Style: Multiple, Weight: 2.30 ct. t.w., Size: 6-7 mm)
All weights and measures are approximate.
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420.00 ct. t.w. Multi-Stone Torsade Necklace With Sterling Silver Clasp. 18"
Super Deal: $100.00
Multi-Stone Torsade Necklace With Sterling Silver. 18.5"
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Multi-Stone and Cultured Pearl Torsade Necklace With Sterling Silver. 18"
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Set of Five Pairs of 25.10 ct. t.w. Multi-Stone Earrings in Sterling Silver
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Turquoise and 2.60 ct. t.w. Multi-Stone Pendant in 18kt Gold Over Sterling
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Learn More About: Sterling Silver Polished Finish Lobster Clasp Topaz Citrine Peridot Amethyst Garnet


text:
- Critic & User
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- Codes
& FAQs
- Gameplay
- Similar
Game Details
- Release Date 3/8/2007
- Publisher Eidos
- Platform PS2
- Genre Arcade/Puzzle
- Number of Players 2
Game Description
Carol Vorderman, the ultimate Sudoku expert, will show you how to play and conquer the number game phenomenon that is sweeping the world! There are over one million puzzle boards to choose from, meaning countless hours of puzzling fun. Learn step-by-step strategies to playing the game, or test your skills in head-to-head matches. Four difficulty levels mean all players, from beginner to expert, are welcome. Multiple game modes let you choose a casual game or the chance to take on the master and win your Sudoku black belt. You can choose the level of help you get from the Tutor, so you can tailor your own learning, and if you get totally stumped, the powerful Puzzle Solver will come to the rescue.
User Reviews
Average Member Rating: 5.4 out of 10
Same old. (5 out of 10)
posted by Bazza702 (BILOXI, MS) on Sep 17, 2009
Member since Apr 2006
Member since Apr 2006
I was really looking forward to this game. I have been a fan of Carol's since high school when she first became famous on Countdown in my home country of England. I am also a Sudoku addict and have been for many years. Putting all this together and as you might expect I was thinking great things of ...more
Specs & Requirements
Modes Simultaneous, Versus, Career, Arcade, Training, Challenge
Similar Games
- Grand Theft Auto IVRelease 4/28/2008
- God of War IIIRelease 3/15/2010
- Guitar Hero IIRelease 11/6/2006


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Well Played: Charlene
The royal really revved it up for the F1 Grand Prix. Read More »
Well Played: Reese
The pregnant star looked lovely in blue at Cannes. Read More »
Well Played: Kirsten
Kirsten Dunst returned to her Lisbon roots at Cannes. Read More »
Well Played: Jessica
Jessica Chastain goes for a low dip Cannes. Read More »
At first, I wasn't sure if I should post this look as a "Well Played," "A Lot Of Look," or "Love It Or Leave It." In some ways, with the animal print VANS and printed leggings, it is a lot of look. And for some, that look may be kind of fugs. But I think Whitney Port totally pulls it off and exudes a feminine, skater-girl vibe. Could I rock this? No. But I don't do leggings of any sort. [Photo: Bauer-Griffin]


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My Profile
Member since Oct 2011
Flag This ProfileFlag as Inappropriate
Reviewed Overnight Cinnamon Rolls
Oct 17, 2011 in Food Network Community Toolbox on FoodNetwork.com
"These are fantastic! The recipe was very easy to follow. I'm not very experienced and this recipe is fool-proof. I doubled the icing and had plenty leftover. These are a hit at my home, with the neighbors and I'll be preparing them again for my bible study group. """


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Jonathan Howell: Man accused of stealing woman's purse, then her SUV
A man faces carjacking charges after police said he robbed a woman in West Palm Beach, stole her truck, drove it to Lake Worth and then crashed it along Interstate 95.
Police said it happened shortly before 6 p.m. Thursday in a parking lot along the 1900 block of Palm Beach Lakes Boulevard, just west of I-95 in West Palm Beach.
MUGSHOTS: Who Got Arrested In South Florida?
Investigators said a woman was walking to her truck when Jonathan Howell, 33, grabbed her neck, stole her purse and then took off in her vehicle.
Police said they spotted the woman's Nissan XTerra in Lake Worth and eventually caught the man when he crashed along the I-95 northbound exit ramp to Okeechobee Boulevard.
Police said Howell tried to run away but was caught within a matter of seconds.
Howell was treated at a local hospital for minor injuries, police said.
He is locked up in the Palm Beach County Jail and is scheduled to make his first appearance in court Friday morning.
Follow Chris McGrath on Twitter at @wpbf_chrismcg
BEST OF THE WORST: Mugshot Hall Of Shame On WPBF.com:
Copyright 2014 by WPBF.com All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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East Coast Media Can't Handle the Chelsea Truth
Female entertainers who make upwards of $20 million a year normally get a little more media respect than Chelsea Handler. According to an entertaining profile in Newsweek, that's how much the host of E!'s Chelsea Lately earned in 2010 thanks to an ever-expanding empire that encompasses books, large venue stand-up comedy performances and various in-progress TV spinoffs.
Handler tells reporter Jennie Yabroff she is aware of the discrepancy between her success and media coverage, but that overall she's fine with "being a bit under the radar." Writes Yabroff:
Unlike Tina Fey or Jon Stewart, Handler is not a darling of the media elite. She rarely appears on magazine covers. She's never hosted Saturday Night Live (though a Facebook group is lobbying for this to happen). Her books aren't reviewed by The New York Times. And when they do notice her, critics are unkind.
After Handler hosted the Video Music Awards, the Times called her performance "among the worst in the show's history." The New Yorker described Chelsea Lately as "too sloppy by half."
One exception to the NYC media bias is friend Katie Couric, who is favorably quoted several times in the Newsweek piece. The 35-year-old Handler insists in the article that she wants to be done with the on-camera portion of her career by the time she hits 40.


text:
Latest Updates
This is the stream of consciousness where there is a streaming list of updates from twitter and comments from the site.
A Summer of Pride!
Here's a list of all (that we know of!) Pride events happening this Summer across the North West.
- 12:17 PM Jun 23rdviaLGF Website
The LGF celebrates Manchester Day Parade in rainbow colours
The Lesbian & Gay Foundation (The LGF) is celebrating Manchester and other LGB&T friendly cities from around the world for this year's Manchester Day Parade on Sunday 22nd June.
- 16:29 PM Jun 21stviaLGF Website
thumbs up
- 16:51 PM Jun 19thviaLGF
Safer Sex Tips
Safer sex info for women who have sex with women.
- 18:21 PM Jun 13thviaLGF Website
Carers stories
- 10:55 AM Jun 12thviaLGF Website
Getting the help you need
- 10:55 AM Jun 12thviaLGF Website
Being lesbian, gay, bisexual or trans and a carer can bring about additional issues.
- 10:54 AM Jun 12thviaLGF Website
The LGF Volunteer Awards 2014
The Lesbian & Gay Foundation's (The LGF) annual Volunteer Awards ceremony was held during National Volunteer's Week and celebrated the achievements of all our fabulous volunteers.
- 15:29 PM Jun 10thviaLGF Website
Who are your Homo Heroes for 2014?
Nominations for The Lesbian & Gay Foundation's Homo Heroes Awards 2014 are now open so get nominating for the individuals, groups and organisations you feel have helped to make a difference to the community over the past year.
- 15:14 PM Jun 10thviaLGF Website
Make schools safer
Homophobic bullying is still endemic in UK schools, but our Safer Schools Packs help schools challenge homophobic bullying, support their lesbian, gay and bisexual students and promote understanding.
- 11:28 AM Jun 10thviaLGF Website
Spotlight on your cervix! What is cervical screening and do lesbian and bi women need to bother?
This week (8th – 14th June) is Cervical Screening Awareness Week, an annual initiative aimed at raising awareness of cervical screening and encouraging women to get regular screens. But what is cervical screening? And why should we bother?
- 16:36 PM Jun 9thviaLGF Website
GP experiences survey
- 11:51 AM Jun 5thviaLGF Website
Can a person get in to trouble for simply standing around in the cruising area, and can the police move you on if you are just in the area for a rest. Kind Regards
- 09:49 AM Jun 4thviaLGF
Homo Heroes Awards 2013 - your winners!
This year's Homo Heroes Awards received almost 500 nominations across 8 categories, and then went on to receive over 6000 individual votes from across the UK and beyond!
- 22:18 PM Jun 2ndviaLGF Website
"I'm not always open about my sexual orientation, especially in a healthcare setting but after seeing The LGF's condoms on the reception desk and in the consultation room, I chatted to the nurse...
- 10:30 AM May 28thviaLGF
Boys who like boys: A survey of understanding about sex
NAT (National AIDS Trust) have launched a nation-wide survey of young gay, bisexual men and other men who have sex with men (MSM) about where and how they learn about sex, relationships and HIV and whether the information and support they receive is helpful.
- 15:29 PM May 23rdviaLGF Website
Men! Get a tenner for talking to us!
Join our feedback group and receive a £10 shopping voucher! Help us find out about what men who have sex with men want to know about anal cancer and screening for the disease.
- 17:09 PM May 21stviaLGF Website
The LGF receives GSK Impact Award
The Lesbian & Gay Foundation (The LGF) received an award of £30,000 for helping to improve the health of lesbian, gay, bisexual (LGB) people by successfully campaigning for NHS England to monitor the sexual orientation of staff and patients at the GSK Impact Awards ceremony last night.
- 16:12 PM May 20thviaLGF Website
Tameside get's ready for Pride first!
On 28th June, Tameside will be holding its first ever Pride event and The Lesbian & Gay Foundation will be taking part. Here we talk to Bev Taylor from Tameside and Oldham Gay Society about what we can all look forward to on the day.
- 15:53 PM May 19thviaLGF Website
Bake the Rainbow, Share the Rainbow
The Lesbian & Gay Foundation (The LGF), in partnership with the Village Bakers, are encouraging people to bake their own rainbow coloured creations to mark International Day Against Homophobia, Biphobia and Transphobia (IDAHOBIT) on Saturday 17th May 2014.
- 13:27 PM May 17thviaLGF Website
The LGF launches Hate Crime Reporting Web-app
To mark International Day Against Homophobia, Biphobia and Transphobia (IDAHOBIT), The Lesbian & Gay Foundation (The LGF) have launched a new hate crime reporting web-app to encourage people to report hate crime incidents quickly and anonymously, if needed, and to ensure that no hate crime incidents go unreported.
- 00:43 AM May 17thviaLGF Website
Celebrate IDAHOBIT 2014 & The Rainbow Connection
International Day Against Homophobia, Biphobia and Transphobia (IDAHOBIT) takes place every year on 17th May, and this year The LGF is planning a number of ways to mark this important date in our calendar - to raise awareness of hate crime against lesbian, gay, bisexual and trans (LGB&T) people and to encourage reporting of hate crime.
- 16:38 PM May 16thviaLGF Website
Hear from awarded GPs
We asked some questions to a selection of the GP surgeries who are part of our 'Pride in Practice' scheme.
- 15:44 PM May 16thviaLGF Website
Privacy Policy
This privacy policy sets out how "LGF Online" uses and protects any information that you give "LGF Online" when you use this website.
- 15:24 PM May 16thviaLGF Website
Hate crime vigil for International Day Against Homophobia, Biphobia and Transphobia
A unique vigil to remember victims of hate crime will be held in Manchester on Saturday 17th May to mark International Day Against Homophobia, Biphobia and Transphobia (IDAHOBIT), including guest speaker Sylvia Lancaster.
- 15:06 PM May 16thviaLGF Website
Barclays support International Day Against Homophobia, Biphobia and Transphobia
Barclays bank is collaborating with The Lesbian & Gay Foundation (The LGF) over International Day Against Homophobia, Biphobia and Transphobia (IDAHOBIT) by displaying messages of support on their cash machines across the UK.
- 10:43 AM May 14thviaLGF Website
In the circa 1950's film about "The Homosexual" on YOUTUBE, the theme here is..."Beware of the SICK Homosexual ! " Labeling all gay men as sick and ill,...and all as child predators. By today's stand...
- 15:10 PM May 13thviaLGF
National LGB&T Partnership joins forces with Dying Matters
The National LGB&T Partnership are joining forces with the Dying Matters Coalition to encourage and support people from lesbian, gay, bisexual and trans communities to talk openly about end of life issues in the run-up to Dying Matters Awareness Week.
- 09:50 AM May 13thviaLGF Website
Part of the Picture - LGB Drugs and Alcohol Research
The Part of the Picture (POTP) research project is a five-year partnership between The Lesbian & Gay Foundation (LGF) and the University of Central Lancashire (UCLan), funded by the Big Lottery Fund's research programme between 2009-2014.
- 15:57 PM May 12thviaLGF Website
National Network
The National Network of Lesbian and Bisexual Women's Service Providers brings together organisations that are providing specialist services for self-identifying lesbian and bisexual women to improve service provision and enhance knowledge.
- 16:27 PM May 9thviaLGF Website