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|9-10 years ago when I lived in North Carolina's "High Country" -- Watauga and Jefferson Counties -- I was given an unusual squash. It was large, round, pink, and slightly flattened, though not so flat as the then newly popular "Cinderella" pumpkins. I was told that it was a "pie pumpkin" and told to save the seed.
It was one of the most delicious squash I've ever tasted.
It was a couple years before I could try to plant any of it and I was never able to get it to grow. I had believed that at some point during multiple moves that seed had encountered conditions that had killed it.
This year I made a last effort. I threw handfuls of the seed into the best place I had -- the spot where I'd removed an old compost heap. To my great delight as many as 1 in 3 of those seeds have sprouted.
I'll be very interested to see what the pumpkins are like. Especially to compare them to the Long Island Cheese that I'm growing since that's the best match I've ever found for that pumpkin's description.
Follow-Up Postings:
|Saying it is similar to long island cheese and that it was referred to as a pie pumpkin, makes me thing you had an amish pie pumpkin. But I don't know if I would consider it round or pink (I think it is shaped like a strawberry and tan colored). Anyway it is supposed to be a delicious pumpkins for pie. Here is a picture:
- Posted by iam3killerbs 7 NC Sandhills (My Page) on Sat, Jun 20, 09 at 12:55
|No, it was nothing like that shape.
It was wide and flattened. It looked very much like the pictures of the Long Island Cheese except that it was larger than the description for that variety. Probably about 15lbs. I remember getting multiple meals from it.
|Are you planning to hand pollinate, or are you isolated enough from others that you will be able to save seed?
- Posted by iam3killerbs 7 NC Sandhills (My Page) on Mon, Jun 22, 09 at 21:03
|I have a number of different winter squash planted with multiples of each species since I'm in a new zone and need to see what will grow well. My plan is to hand-pollinate some of these.
They may be Long Island Cheese or they may be some little-known, Appalachian strain. I'll find out when I can sit the two varieties side by side.
- Posted by iam3killerbs 7 NC Sandhills (My Page) on Fri, Jun 26, 09 at 13:09
|The plants are old enough now to start to compare them. The Long Island Cheese does not have silver mottling on its leaves. The plants from the resurrected seed, which I'm tentatively calling "Watauga Pie Pumpkin", do have the silver mottling. Its too soon to see if they have it to the same extent that the Argonaut squash do.
I'll give them a few more days to put on some new leaves then I'll post some pictures.
- Posted by dirtdauberz5mo (My Page) on Fri, Jun 26, 09 at 17:11
|Keep us posted, I'm interested. The Tatume squash I planted had the silver mottling on the first leaves, but subsequent larger ones have been solid green....
|Hi! I think I might have found your squash/pumpkin? Does this look like it? It's called Boston Marrow.
- Posted by iam3killerbs 7 NC Sandhills (My Page) on Wed, Jul 1, 09 at 22:25
|No. My squash is definitely not a Boston Marrow. That photo doesn't match the other photos of Boston Marrow I've seen and the original squash didn't match either your photos or the other type. http://www.cherrygal.com/images/SquashBostonMarrow.jpg My squash was both a flattened globe shape and a pale color more pink than orange but, IIRC, not as tan as a butternut. It was nowhere near as boldly colored as any version of the Boston Marrow.
Its possible that my squash may be a relative of Old-Fashioned Tennessee Vining Pumpkin, though the ones in the picture are taller and less symmetrical. http://www.southernexposure.com/productlist/prods/53603.html
I'll have photos next week of my "Watuaga Pie Pumpkin" plants to compare to the Long Island Cheese plants. They are obviously different even young -- my unknown one has the silver mottling on the leaf while the Long Island Cheese does not.
- Posted by iam3killerbs 7 NC Sandhills (My Page) on Fri, Jul 3, 09 at 10:53
- Posted by sazji 8bNW Turkey (firstname.lastname@example.com) on Sun, Jul 5, 09 at 18:13
|I'm fascinated! I'm sorry I can't help you with the identification but I love growing winter squash, espeically interesting old varieties. Beautiful leaves too. Can I request a little seed if you have extra? I can send you seed of a very good and slightly bizarre one from Turkey (there's a thread on it here, the Adapazari squash). I'm growing Rouge Vif d'Etampes ("Cinderella") and Marina di Chioggia this year.
- Posted by iam3killerbs 7 NC Sandhills (My Page) on Sun, Jul 5, 09 at 19:48
|I do have some extras of my very old seed. I'm going to hand-pollinate them when the blossoms start so I can get good seed in this year's crop.
Assuming that my seed comes true to my memory and my hand-pollination works I'm intending to offer the seed to gardeners who's like to try it once I've got a fresh supply.
If you want to take your chances with some of my 10-year-old seed -- I can't guarantee any degree of reliable germination -- I'll be happy to send some. And I'd love to try the Adapazari squash. :-)
- Posted by sazji 8bNW Turkey (firstname.lastname@example.com) on Mon, Jul 6, 09 at 16:43
|Well, it's too late for this year anyway I think; just make sure you bag those female flowers the day before they open if you're growing any other varieties around! :) By the way the yahoo email address is wrong; I'm using email@example.com now. I tried resetting it but it won't let me do it without picking a state (in US - I live in friggin' Istanbul!). I don't have Adapazarý seed just now but the markets are full of it in the fall and I'll get you some. There's a big oblong pumpkin they grow in the east of Turkey that i want to get my hands on too. (Heh...I said "no more big squash" but who am I fooling...)
- Posted by iam3killerbs 7 NC Sandhills (My Page) on Mon, Jul 6, 09 at 16:50
|I've studied the thread on how to hand pollinate squash and am going to practice on my summer squash this week.
Hopefully I'll have good, fresh, uncrossed Watauga Pie Pumpkin seed come fall.
Fortunately, since I have 4 kids big squash aren't a problem for me.
- Posted by gardener_mary 6 MA (My Page) on Sat, Jul 11, 09 at 0:21
|Your pumpkin/squash sounds very interesting and looks very nice. If you are open to sharing a few I would be willing to take a chance with those 10 yr old seeds.
Good gardening, Mary
- Posted by iam3killerbs 7 NC Sandhills (My Page) on Mon, Aug 3, 09 at 11:43
|Here are some photos of the largest plant and the very first female flower. Its growing on top of a compost pile and vining across some sweetpotatoes.
I'll keep adding photos as things grow and develop.
|I am growing a squash which I received from Garden Web member "rodger" who lives in NC. It's called Old Timey Cornfield Pumpkin and has variable shaped fruit. So far I've noted mango shaped, watermelon shaped and ridge fruit. I planted about 6-8 plants and they are taking over an entire garden! Here's a picture of the leaves of Old Timey Cornfield Pumpkin. Rodger says that this one was traditionally grown in the corn, in that neck of the woods and that they used the fruit for pies, even when they were still green. (I don't know how they did that!)
Here's a picture of some of the vine & leaves, along with a mango shaped fruit which had recently been hand pollinated.
- Posted by iam3killerbs 7 NC Sandhills (My Page) on Thu, Aug 6, 09 at 17:45
|Looks like the leaves are quite similar, just slightly deeper lobes and a coarser tooth around the edge. A cousin, perhaps?
I should be able to get a better picture of the first female flower tomorrow.
The ones I saw when living in the High Country were uniformly round and slightly flattened with very little variation in size and shape.
|Hey, guys. Just curious if iam3killerbs was able to get mature fruit and (more importantly) fresh seeds... Did the fruit match your memories? Were you able to track down the actual variety?
- Posted by John Allan Tallant 7(firstname.lastname@example.com) onSat, Apr 3, 10 at 0:52
|I grew up in Catawba County in NC and my Daddy gave me some seeds of what he called a mountain pumpkin 30 years ago or so. He said he had looked for them for years. I have kept growing them since then and the leaves look like the pictures. They set roots along the vines as they run and I believe they are a type of Cucurbita moschata. The pumpkins are flattened and moderate in size. They make great pies, the flesh is dark orange and flavorful. I have enough seeds from past years to share if anyone is interested is trying to grow them.
- Posted by christine00 (My Page) on Thu, Apr 8, 10 at 16:10
|i would be interested in growing a few! winter squash are fascinating!
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|28 Sep 2012
Windows 7 Themes interfering with FireFox/Gadgets useability
I have a custom theme that I have been using for the past month.
It is a theme with dark menus that I have come to love. I have never had problems with it interfering with Firefox or desktop gadgets before.
Last night, I tried an 'Aero' theme and decided I didn't like it and switched back to my old theme. However, now whenever firefox is loaded, the page background appears the wrong color and pictures do not load. This happens for youtube, facebook, and netflix (all opened in my homepage). I have uninstalled firefox and reinstalled twice since this issue has come up and nothing has changed.
Gadgets also do not load correctly (appearance). This has never occurred before.
This problem goes away when I use an Aero theme or the Windows 7 classic theme, but returns when I use my custom theme or a high contrast theme.
I do not believe I changed any settings under my custom theme, but if we have to, we could run through all the setting under
Appearance and Personalization > Personalization > Window Color and Appearance
To see if I have accidentally filled a field that affects Firefox/gadgets
Here are some pictures for explanation:
So this is what the gadgets should be doing and this is with the Windows 7 Aero Theme
And this is how Firefox looks
And this is how the Menu looks
Everything is fine with this theme.
Okay, so this is the "Life" Theme. This is a dark theme that doesn't interfere with gadgets/firefox.
And this is how Firefox looks
And this is how the menus look
Seems to be fine, despite the obvious and drastic change of colors.
Now here's where problems come in with my theme.
Here's how gadgets look.
Here's how Firefox looks
Here's how the menus look
I never had this problem until last night and don't remember changing anything except for switching to Aeros and back.
Is there something I'm missing? Is there a way to set windows themes to not interfere with other programs?
Thanks a lot to anyone who answers, I've become really attached to this theme and would hate to lose it.
|My System Specs
|28 Sep 2012
Welcome to the Seven Forums
Which one did you use the Universal Theme Patcher or UxStyle to enable custom themes?
|My System Specs
|29 Sep 2012
Do you mean in Firefox or in Windows?
I don't believe I initially installed any additional software to alter windows themes.
I eventually did install Universal Theme Patcher, it was an impulse decision that I made because I was trying to change the color of the taskbar in windows (which I eventually decided I didn't even want to do).
I have uninstalled it though.
There was a piece of software (add-on) that I installed in Firefox, after the issue came up, to try and fix the problem, but I ended up uninstalling it because I had no luck with it. It now doesn't show up in Firefox add-ons. However, I haven't checked the Program Files (x86) folder and there could be some left over files there.
Like I said, I have reinstalled Firefox twice since this incident, but maybe there are still files left over that are causing this to happen.
I'm somewhat comfortable/proficient with Windows, but I honestly don't know where to start backtracking and I don't even know how the problem originally came up.
Thanks for you response.
|My System Specs
|29 Sep 2012
Windows 7 Home Premium x64 SP1
Welcome to Seven Forums NewUserOne. You would have had to use some sort of system patcher to get your 3rd party custom theme working in the 1st place? I would suggest running the System File Checker, then repatch to enable your custom theme.
SFC /SCANNOW Command - System File Checker
A Guy
|My System Specs
|29 Sep 2012
Microsoft Windows 7 Home Premium 64-bit 7600
i would just system restore if you want it back with your dark theme working as it did the previous night.
sfc scan will reset windows themes and file icons to default .
|My System Specs
|29 Sep 2012
Like A Guy said to use a custom theme you will need to do 1 of these 2 ways of Enabling custom themes for it to work.
Enabling Custom Themes - Windows 7
Theme - How to Apply Custom Themes
Do the scan A Guy posted then repatch
|My System Specs
|29 Sep 2012
I did the SFC Scan and got this message:
Then when to CBS Logs and got the message: "Access is denied" and it opens a blank notepad file.
I have restarted the computer and nothing has changed cosmetically and I have still having the same problems with Firefox.
I would like to repatch the problems, but I need to be able to see them.
Should i just do a system restore?
|My System Specs
|29 Sep 2012
Should i just do a system restore?
Try the sfc /scannow 3 times with a restart after each scan.
|My System Specs
|29 Sep 2012
Should I try the 3 SFC/Restart first?
( should I keep system restore as last resort ? )
Also, there were some modifications like removing start button and removing start menu user picture, will these be altered/reset by system restore?
Thanks SO MUCH for your quick response!
|My System Specs
|29 Sep 2012
Should I try the 3 SFC/Restart first?
should I keep system restore as last resort
|My System Specs
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text:
OYO Geospace Reports Fiscal Year 2011 First Quarter Results
OYO Geospace (NASDAQ: OYOG) today announced net income of $8.2 million, or $1.30 per diluted share, on revenues of $43.1 million for its quarter ended December 31, 2010. This compares with net income of $1.1 million, or $0.18 per diluted share, on revenues of $26.3 million in the comparable quarter last year.
"Our first quarter of fiscal year 2011 produced outstanding financial results due to several factors. Foremost, during the quarter we delivered almost 29,000 channels of our GSR wireless data acquisition system to various customers, including 7,800 rented channels. GSR feedback from our customers has been positive, and we are pleased to hear about productivity improvements to our customers' operations. We now have almost 60,000 GSR channels sold, rented or available for rent. In addition, other important products contributed significantly to the first quarter's financial performance, including our marine and borehole reservoir monitoring products," said Gary D. Owens, OYO Geospace's Chairman, President and CEO.
"To meet our growing product demand, we increased our worldwide employee headcount during the first quarter from 891 to 976, an increase of 9.5 percent. The added personnel, especially at our Houston manufacturing plant, improved our factory productivity and utilization. Backlog at December 31, 2010 has more than doubled since the beginning of our fiscal first quarter."
"Cash flow remained healthy throughout the first quarter. During the first quarter ended December 31, 2010, we paid off a $7.7 million mortgage on our Pinemont property in Houston, Texas and ended the first quarter debt free.""At this time, we are optimistic about the immediate outlook. Regarding the second quarter of fiscal year 2011, we expect to fulfill sales commitments for approximately 11,000 single-channel GSR units. In addition, we expect to fulfill rental commitments for another 12,000 single-channel GSR units during the second quarter, which will bring our total GSR rental commitments to approximately 20,000 channels. Other key product categories, including marine, borehole and sensor products also have ample levels of commitment for delivery in the second quarter. Although our quoting activities are high, we remain cautious about the future outlook given our limited visibility beyond the next quarter. However, we are encouraged with our first quarter results and with the feedback we are receiving from our customers."
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text:
Solazyme, Inc. Prices Offering Of $115 Million Of 6.00% Convertible Senior Subordinated Notes
Solazyme, Inc. (NASDAQ: SZYM) announced today the pricing of its offering of $115 million aggregate principal amount of Convertible Senior Subordinated Notes due 2018 (the "Convertible Notes") in a private placement under the Securities Act of 1933, as amended (the "Securities Act"). Solazyme also granted the initial purchaser a 30-day option to purchase up to an additional $10 million aggregate principal amount of Convertible Notes solely to cover over-allotments. The sale of the Convertible Notes is expected to close on January 24, 2013, subject to customary closing conditions.
Solazyme expects that the net proceeds from this offering will be approximately $109.8 million, after deducting discounts to the initial purchaser and estimated offering expenses payable by Solazyme. Solazyme intends to use the net proceeds of the offering to fund project related costs and capital expenditures and for general corporate purposes.
The Convertible Notes will bear interest at a fixed rate of 6.00% per year, payable semiannually in arrears on August 1 and February 1 of each year, beginning on August 1, 2013. The Convertible Notes will mature on February 1, 2018, unless earlier repurchased or converted. Solazyme may not redeem the Convertible Notes prior to maturity. The initial conversion price will be approximately $8.26 per share of common stock and, under certain circumstances, Convertible Note holders will be entitled to additional payments upon conversion. The Convertible Notes are described in more detail in the Company's Form 8-K filed January 18, 2013.
The offering is being made to qualified institutional buyers pursuant to Rule 144A under the Securities Act. Neither the Convertible Notes nor the shares of Solazyme's common stock issuable upon conversion of the Convertible Notes have been or are expected to be registered under the Securities Act or under any state securities laws and, unless so registered, may not be offered or sold in the United States or to U.S. persons except pursuant to an exemption from, or in a transaction not subject to, the registration requirements of the Securities Act and applicable state securities laws. This press release does not constitute an offer to sell or the solicitation of an offer to buy any securities, nor shall it constitute an offer, solicitation or sale in any jurisdiction in which such offer, solicitation or sale is unlawful.
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text:
Cheerful, optimistic Nadja is one of many English orphans living in the quaint Applefield Orphanage. Yet one fateful day, when the orphange is attacked by men looking for her mother's brooch, Nadja learns that her mother may still be alive after all. Hoping to protect the rest of the inhabitants of Applefield and to escape her would-be captors, Nadja runs away from the orphanage and joins the Dandelion Troupe -- a traveling band of circus performers. Filled with the greatest hope, Nadja's grand adventure begins in a search for her mother and her own identity...
2 votes
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1 votes
Well it's been a little while since I've watched this, but what the heck, let's try a review. Ashita no Nadja (50 ep) is about a girl who decides to go on a journey to search for her mother, BUT -don't be suprised- somebody else doesn't want her to meet with her mother/wants something from her and everyonce and while will try to stop her. There's also that little snibit of romance with the blond... read more
This anime is awesome. It has a mix of romance, mystery,tragic,and adventure. The story takes place in Europe and starts of with a orphan named Nadja. She lives in an orphanage peacefully until some robbers come by and starts a fire. Nadja tries to run away, and ends up with the Dandilion Travel Performers. On the way she finds new friends ,overcome obstacles, and fine clues about her mom. Usually I don't cry... read more
|Ashita no Nadja
Character Design
If you liked or , you'd like the other because...


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text:
Camping out????????????
Hi you two roughnecks!!! No electric; no phone; no beds; no showers,and no breakfast places. I can't really say with my whole heart- I wish I was there.
Have FUN and keep us posted.
Love you two
Howdy Pardner!
Trip Start Jul 01, 2009
28Trip End Jul 25, 2009
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Best Western
We drove from Moab, UT to Pinedale yesterday crossing some beautiful and wide open spaces.
There were mountains, high desert, hills, valleys mountain passes with very curvy roads and severe drop-offs, the 455 foot high Green River dam in Flaming Gorge National Recreational Area. That's where the deer and antelope play. We saw them when crossing from Utah to Wyoming, the antelope anyway.
Pinedale (population of 1400 before natural gas was found recently) was going to be a place to pass out after about 500 miles of driving. It turned out to be a celebration with live music, fireworks, good Chinese food (better than back home) and lots of friendly people
We're headed to the Tetons tonight and Yellowstone tomorrow. Hard to update a website while camping with no electricity and no Internet. We'll try...


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Nick Punto Rumors
Odds & Ends: Guerrier, McCutchen, Blue Jays, Punto
As the baseball world says goodbye to Cubs great Ron Santo, here are some news tidbits heading into the weekend…
- The Red Sox have made an offer to reliever Matt Guerrier, reports WEEI.com's Alex Speier (as passed along in a tweet from WEEI.com's Rob Bradford).
- Rob Biertempfel of the Pittsburgh Tribune-Review looks at how Jay Bruce's extension might influence a future extension offer from the Pirates to Andrew McCutchen.
- Lyle Overbay would be a familiar solution to Toronto's search for a first base/DH partner for Adam Lind, but MLB.com's Gregor Chisholm thinks Overbay "does not appear to be a good fit" since Overbay wants an everyday job. Chisholm's piece also contains several quotes from Alex Anthopoulos from the winter meetings and what the Jays might look to do during the rest of the offseason.
- The Indians and Nick Punto had "meaningful negotiations" at the winter meetings, reports MLB.com's Jordan Bastian.
- Manny Ramirez will receive $15MM in deferred payments from the Dodgers over the next three years and $1.94MM for each of the next 16 years from the Red Sox, reports Gordon Edes of ESPNBoston.com (with a tip of the cap to Cot's Baseball Contracts).
- Larry Stone of the Seattle Times looks back at the 11-year contract Dave Stieb signed with the Blue Jays before the 1985 season.
- Also from Stone, Jack Zduriencik says the Mariners could be in the market for an extra infielder.
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Full Story | Comments | Categories: Andrew McCutchen | Boston Red Sox | Cleveland Indians | Los Angeles Dodgers | Lyle Overbay | Manny Ramirez | Matt Guerrier | Nick Punto | Pittsburgh Pirates | Seattle Mariners | Toronto Blue Jays
Indians Notes: Colon, Encarnacion, Choo, Punto
The Indians have been quiet this offseason, but GM Chris Antonetti is making progress on potential moves, as MLB.com's Jordan Bastian and others report:
- The Indians have some interest in bringing Bartolo Colon back to Cleveland, according to Enrique Rojas of ESPNDeportes (on Twitter). The right-hander pitched for the Tribe from 1997-2002 and is back on the radar and attempting a comeback. He last pitched in the majors for the 2009 White Sox. Paul Hoynes of the Cleveland Plain Dealer disagrees, shooting down the idea on Twitter.
- The Indians' interest in Edwin Encarnacion appears to have cooled, Bastian notes on Twitter.
- The Indians will discuss the possibility of a Shin-Soo Choo extension with agent Scott Boras this offseason. I looked at Choo's case for an extension back in September.
- Antonetti said the club could have interest in adding an infielder. They are interested in Adam Everett, according to ESPN.com's Jayson Stark.
- The Tribe met a number of agents today, including the representatives for free agent infielder Nick Punto.
- The Indians are close to signing former Rockies catcher Paul Phillips to a minor league contract.
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Full Story | Comments | Categories: Bartolo Colon | Cleveland Indians | Edwin Encarnacion | Nick Punto | Shin-Soo Choo
Odds & Ends: Hardy, Punto, Dunn, Marlins, Lee
Some items to wrap up the week…
- The Pirates were close to a trade for J.J. Hardy on Thursday night, reports Ken Rosenthal of FOXSports.com. Pittsburgh is known to have an interest in Hardy and could still work out a deal given that the Twins tendered Hardy a contract.
- There is "mutual interest" between Nick Punto and the Indians, reports Paul Hoynes of the Cleveland Plain Dealer. (Twitter link) The two sides will continue their talks during the winter meetings.
- Yahoo Sports' Big League Stew blog collects some of the Washington media's reaction to Adam Dunn leaving town, and it isn't very positive.
- It's looking increasingly unlikely that Arizona will trade Justin Upton, but if Upton is moved, it won't be to Florida, writes Juan C. Rodriguez of the South Florida Sun-Sentinel. Rodriguez says the Marlins are looking for a left-handed bench bat and possibly a left-handed reliever, though the club is unlikely to re-sign Will Ohman.
- Phillies assistant GM Scott Proefrock tells Fox Sports Radio's Jim Bowden (Twitter link) that his club isn't interested in bringing back Cliff Lee. "That ship has sailed," Proefrock said.
- Erik Bedard tells Larry Larue of the Tacoma News Tribune that he was offered a guaranteed deal from another club but turned it down to sign a non-guaranteed contract with Seattle.
- The Mariners "are becoming a West Coast version of the Orioles, a place top-tier free agents avoid because the stench of losing is overwhelming," writes Yahoo's Steve Henson in his winter meetings preview.
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Full Story | Comments | Categories: Adam Dunn | Chicago White Sox | Cleveland Indians | Cliff Lee | Erik Bedard | J.J. Hardy | Justin Upton | Miami Marlins | Minnesota Twins | Nick Punto | Paul Konerko | Philadelphia Phillies | Pittsburgh Pirates | Seattle Mariners | Washington Nationals | Will Ohman
Twins Pick Up Kubel's Option, Decline Punto's
The Twins exercised Jason Kubel's $5.25MM option for 2011 and turned down Nick Punto's $5MM option, according to MLB.com's Kelly Thesier (on Twitter).
Kubel posted a .249/.323/.427 line this year and his lowest OPS since 2006. He hit 21 homers, spending most of his time at right field and DH. The 28-year-old would have been a Type A free agent, so Minnesota could have obtained draft picks if Kubel had turned down arbitration to sign elsewhere. As we predicted in August, the Twins chose to retain Kubel for another season.
Punto, 33 next month, batted .238/.313/.302 in 288 plate appearances and played short, second and third. As Thesier pointed out earlier this month, the Twins were not expected to pick up Punto's option. He is not a ranked free agent, so the Twins won't get compensation picks if they offer arbitration and he signs elsewhere. An offer of arbitration for Punto seems extremely unlikely.
Full Story | Comments | Categories: Jason Kubel | Minnesota Twins | Nick Punto | Transactions
Odds & Ends: Twins, Izturis, Rangers, Yankees
Seven years ago today, Luis Castillo popped a ball up into the stands at Wrigley Field and a fan caught it, even though Moises Alou was right there. The Cubs were five outs away from clinching a World Series berth, but they ended up losing the 'Steve Bartman game' and the 2003 NLCS. Here are your links for Thursday…
- The Twins aren't expected to bring Orlando Hudson back or pick up Nick Punto's $5MM option, according to MLB.com's Kelly Thesier.
- Cesar Izturis, a favorite of Buck Showalter's, seems more likely to return to Baltimore than other Orioles free agents, according to Roch Kubatko of MASNSports.com. Last month, Izturis told MLBTR that he "definitely" wants to return to Baltimore.
- Yankees GM Brian Cashman tells Joel Sherman of the New York Post that he's "comfortable" with the fact that the Yankees didn't complete their near-trade for Cliff Lee. The lefty will take the Yankees on in the ALCS and he figures to be a difference-maker.
- Mark Teixeira told Kristie Ackert of the New York Daily News that he and Alex Rodriguez are happy for Michael Young and the Rangers. Both Teixeira and Rodriguez spent years in Texas before joining the Yankees, but they don't figure to show much mercy in the League Championship Series.
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Full Story | Comments | Categories: Alex Rodriguez | Baltimore Orioles | Cesar Izturis | Cliff Lee | Mark Teixeira | Minnesota Twins | New York Yankees | Nick Punto | Orlando Hudson | Texas Rangers
Twins Rumors: Pavano, Cabrera, Punto
The Twins and Carl Pavano are both interested in making a deal, but it's unlikely we'll see anything finalized before Pavano hits the open market, according to Joe Christensen of the Minneapolis Star Tribune. The Twins have exclusive negotiating rights for now, but Pavano's likely to test the open market first.
The righty made $4.35MM this season, mostly by reaching performance incentives. This time, Pavano's agent suggests his client deserves more guaranteed money. Pavano has repeated that he enjoyed playing for the Twins after they acquired him from the Indians in August, so a return seems possible.
Pavano is a Type B free agent; the Twins will get a supplementary round pick if they offer arbitration only to see Pavano sign elsewhere.
Another Twins free agent, Orlando Cabrera, won't be playing shortstop next year, but manager Ron Gardenhire wants him back regardless. Sid Hartman of the Minneapolis Star Tribune reports that Gardenhire would like Cabrera at second base, J.J. Hardy at short and Nick Punto at third.
Full Story | Comments | Categories: Carl Pavano | Minnesota Twins | Nick Punto | Orlando Cabrera
Twins Still Exploring Shortstop Options
According to Joe Christensen of the Minneapolis Star-Tribune, the Twins are still exploring shortstop options despite signing Nick Punto.
Two of the team's targets do not seem available – J.J. Hardy and Yunel Escobar. The Braves were hard-pressed to discuss Escobar even when they thought they had Rafael Furcal, though the Twins inquired. And Doug Melvin is sticking to his stance on Hardy.
We talked about other failed Twins infield pursuits yesterday.
Full Story | Comments | Categories: Atlanta Braves | J.J. Hardy | Milwaukee Brewers | Minnesota Twins | Nick Punto | Yunel Escobar
Pirates Sign Ramon Vazquez
FRIDAY, 1:51pm: Kovacevic says the Vazquez signing is official at two years and $4MM.
THURSDAY, 11:37pm: Dejan Kovacevic says the Pirates have agreed to the framework of a contract with Vazquez. The contract is not signed yet, and Vazquez needs to take a physical. Another note: the Twins' signing of Nick Punto reduces the already-weak market for Jack Wilson. Kovacevic says the Dodgers have leverage if they want to go after Wilson as a Rafael Furcal fallback.
12:32am: Vazquez's agent told Kovacevic they're "very, very close" but not done. Neal Huntington also said it's not done.
10:51am: Dejan Kovacevic phrases it as "trying to sign" Vazquez.
10:12am: According to ESPN's Buster Olney, the Pirates are on the verge of a two-year, $4MM deal with infielder Ramon Vazquez. Vazquez should be able to step in at either middle infield position if the Bucs manager to trade Freddy Sanchez or Jack Wilson. He needs to sit against lefties though.
Full Story | Comments | Categories: Jack Wilson | Los Angeles Dodgers | Minnesota Twins | Nick Punto | Pittsburgh Pirates | Rafael Furcal | Ramon Vazquez
Twins Re-Sign Punto
According to Joe Christensen of the Minneapolis Star-Tribune, the Twins re-signed infielder Nick Punto to a two-year, $8.5MM deal with an option for 2011. Punto drew interest from the D'Backs, Yankees, Phillies, Mets, and Tigers at the Meetings.
Full Story | Comments | Categories: Minnesota Twins | Nick Punto
D'Backs Rumors: Clark, Punto, Rhodes, Unit
8:10pm: Piecoro says the D'Backs don't want to trade Snyder; in fact, they'd like to extend him.
Piecoro notes talks with Eddie Guardado, but they didn't go far. And Japanese lefty Ken Takahashi is not on Arizona's radar.
7:20pm: The D'Backs have discussed a contract with Tony Clark for '09, says Gilbert.
6:20pm: Rosenthal says the D'Backs want to trade the more pricey Snyder to clear a path for Montero. They could then ink a Gregg Zaun type to back him up.
3:30pm: Gilbert says the D'Backs have a one-year offer out to Loretta.
3:18pm: MLB.com's Steve Gilbert says the D'Backs have not resumed talks with Randy Johnson.
12:12pm: Piecoro says talks between the D'Backs and Mark Loretta have advanced in recent days. They've made a "significant overture" according to Loretta's agent.
2:26am: Nick Piecoro of the Arizona Republic has the latest on the Diamondbacks, in blog posts here and here.
- Piecoro dissects the D'Backs' thought process behind their decision not to offer arbitration to Type A free agent Adam Dunn. He notes that their rumored two-year offer to Dunn was "more of an exploratory offer, nothing formal." They'll stay in touch with Dunn in case the market is not to his liking.
- Free agent targets: Nick Punto, Arthur Rhodes, and the aforementioned Joe Beimel.
- Punto is one of many candidates for second base. Ramon Vazquez was the top target, but he was two guaranteed years rather than one with an option.
- Piecoro wonders if the D'Backs might now be able to scrape together another $3MM or so for Randy Johnson, given the Dunn draft pick savings and Brandon Lyon's decision to decline arb.
Full Story | Comments | Categories: Adam Dunn | Arizona Diamondbacks | Arthur Rhodes | Eddie Guardado | Gregg Zaun | Joe Beimel | Ken Takahashi | Mark Loretta | Nick Punto | Ramon Vazquez | Tony Clark


text:
Investigation Of Buyout Of Capital Gold On Behalf Of Capital Gold Shareholders By Tripp Levy PLLC
Reissuing release to correct ticker symbol for searching purposes: Ticker should read (AMEX: CGC) sted (AMEX: CDC). Also, the acronym CDC should read CGC throughout the release.
The corrected release reads:
Tripp Levy PLLC, a leading national securities law firm, announces an investigation into the proposed acquisition of Capital Gold Corp. (AMEX: CGC). On October 5, 2010, it was announced that CGC entered into an agreement to be acquired by Gammon Gold, Inc. ("Gammon Gold") (NYSE: GRS). Under the terms of the transaction, each common share of Capital Gold will be exchanged for 0.5209 common shares of Gammon Gold and a cash payment in the amount of $0.79 per share. The total consideration for the purchase of 100% of the fully diluted in-the-money shares of Capital Gold is approximately $288 million or $4.57 per Capital Gold share based on Gammon Gold's closing price on September 24, 2010.The investigation concerns, among other things, whether the consideration to be paid to CGC shareholders is grossly unfair, inadequate, and substantially below the fair or inherent value of CGC. Indeed, analysts have projected that CGC's true inherent value is in excess of $10 per share. The investigation further concerns whether the board of directors of CGC may have breached their fiduciary duties by not acting in CGC shareholders' best interests in connection with the sale process of CGC. If you own CGC common stock and you wish to discuss this matter with us, or have any questions concerning your rights and interests with regard to this matter, please contact Tripp LevyTripp Levy PLLC125 East 82 nd Street9 th FloorNew York, New YorkToll Free: 877-772-3975Email: email@example.com Tripp Levy PLLC is a national law firm that specializes in mergers & acquisitions, takeover litigation, shareholder rights, and corporate governance matters in state and federal courts throughout the United States.
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text:
Bill Polian leading candidate in KC
View Single Post
OM analyst
Roby AND Latimer?Who the Hell Knew?
Join Date: Sep 2003
Location: INDY
Posts: 10,130
Malik Jackson
Please, Please let this be true
Polian is as tied to the past in his philosophy as Shanahan is devoted to mediocre sycophants being around him!
I would absolutely love Polian walking into that mess in KC and trying to meld their personnel into his philosophy. He destroyed INDY the last few years without Dungy and has not been a solid drafter in over 6 years. Yes he did a great job in Manning versus Leaf, Edgerrin James versus Ricky Williams, and even getting Freeney in the mid first round. However, he has not been able to draft the new talent coming out of college for a decade. His last major success was Freeney in 2002. Who else has he drafted since then? The ONLY decent player left from him is Antoine Bethea. 2005 til last year he has swung and missed on a ton of players.
Polian would be the perfect guy to take over KC from a broncos perspective. 5 more years of disarray and mediocrity at best IMHO.
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text:
Now showing items 155-174 of 268Next Page
|Articular cartilage defects are most often caused by trauma and osteoarthritis and less commonly by metabolic disorders of the subchondral bone, such as osteonecrosis and osteochondritis dissecans. Such defects do not heal spontaneously in adults and can lead to secondary osteoarthritis. Medications are indicated for symptomatic relief. Slow-acting drugs in osteo - arthritis (SADOA), such as glucosamine and chondroitin, are thought to prevent cartilage degeneration. Reconstructive surgical treatment strategies aim to form a repair tissue or to unload compartments of the joint with articular cartilage damage. In this article, we selectively review the pertinent literature, focusing on original publications of the past 5 years and older standard texts. Particular attention is paid to guidelines and clinical studies with a high level of evidence, along with review articles, clinical trials, and book chapters. There have been only a few randomized trials of medical versus surgical treatments. Pharmacological therapies are now available that are intended to treat the cartilage defect per se, rather than the associated symptoms, yet none of them has yet been shown to slow or reverse the progres sion of cartilage destruction. Surgical débridement of cartilage does not prevent the progression of osteoarthritis and is thus not recommended as the sole treatment. Marrow-stimulating procedures and osteochondral grafts are indicated for small focal articular cartilage defects, while autologous chondrocyte implantationis mainly indicated for larger cartilage defects. These surgical reconstructive techniques play a lesser role in the treatment of osteoarthritis. Osteotomy near the knee joint is indicated for axial realignment when unilateral osteoarthritis of the knee causes axis deviation. Surgical reconstructive techniques can improve joint func tion and thereby postpone the need for replacement of the articular surface with an artificial joint.
|Acquired myasthenia gravis (MG) is a rare antibody-mediated autoimmune disease caused by impaired neuromuscular transmission, leading to abnormal muscle fatigability. The aetiology is complex, including genetic risk factors of the human leukocyte antigen (HLA) complex and unknown environmental factors. Although associations between the HLA complex and MG are well established, not all involved components of the HLA predisposition to this heterogeneous disease have been revealed. Well-powered and comprehensive HLA analyses of subgroups in MG are warranted, especially in late onset MG. This case-control association study is of a large population-based Norwegian cohort of 369 MG patients and 651 healthy controls. We performed comprehensive genotyping of four classical HLA loci (HLA-A, -B, -C and -DRB1) and showed that the DRB1*15:01 allele conferred the strongest risk in late onset MG (LOMG; onset ≥60years) (OR 2.38, pc7.4×10−5). DRB1*13:01 was found to be a protective allele for both early onset MG (EOMG) and LOMG (OR 0.31, pc 4.71×10−4), a finding not previously described. No significant association was found to the DRB1*07:01 allele (pnc = 0.18) in a subset of nonthymomatous anti-titin antibody positive LOMG as reported by others. HLA-B*08 was mapped to give the strongest contribution to EOMG, supporting previous studies. The results from this study provide important new information concerning the susceptibility of HLA alleles in Caucasian MG, with highlights on DRB1*15:01 as being a major risk allele in LOMG.
|A 41-year-old man suffered hypothermic cardiac arrest after water immersion and was transported to our university hospital by ambulance helicopter for rewarming on cardiopulmonary bypass. He resumed spontaneous cardiac activity 6 h 52 min after cardiac arrest and recovered completely.
|Background: Recalcitrant lateral epicondylitis (elbow extensor–origin tendinosis) is a common cause of elbow pain with many treatment options. In the present study, the medium-term results after open release and radiofrequency microtenotomy are reported. Hypothesis: Microtenotomy would provide long-term pain relief that was as good as the open release method. Study Design: Prospective, randomized trial. Methods: Twenty-four patients randomized to either open release or microtenotomy were assessed after 5 to 7 years. Clinical examination and dynamic infrared thermography (DIRT) of both elbows were performed preoperatively and at the medium-term follow-up. Magnetic resonance imaging (MRI) of both elbows was performed at the medium-term follow-up. Results: Significant pain reduction was found using a visual analog scale (VAS) at the medium-term follow-up in both groups compared with the preoperative assessment (P < .005). The Mayo Elbow Performance Score (MEPS) increased significantly in both groups (P < .01). The improvement in grip strength was not significant in either group. There was no significant difference between the groups in terms of VAS, strength, and the MEPS. On the DIRT examinations, there were significantly fewer hot spots at the medium-term follow-up than preoperatively (P ¼ .0067, both study groups together). The MRI examinations revealed grade II changes in the operated elbow in 1 patient in each group at the medium-term follow-up, while all the other MRI examinations revealed a normal tendon. Conclusion: In this prospective, randomized trial with a medium-term follow-up, the results were similar after surgical release and microtenotomy in patients with recalcitrant lateral epicondylitis. The hypothesis was thus verified. Keywords: tendinosis; epicondylitis; microtenotomy; infrared thermography
|The aim of this manuscript is to review the current knowledge in terms of retro-trochanteric pain syndrome, make recommendations for diagnosis and differential diagnosis and offer suggestions for treatment options. The terminology in the literature is confusing and these symptoms can be referred to as 'greater trochanteric pain syndrome', 'trochanteric bursitis' and 'trochanteritis', among other denominations. The authors focus on a special type of sciatica, i.e. retro-trochanteric pain radiating down to the lower extremity. The impact of different radiographic assessments is discussed. The authors recommend excluding pathology in the spine and pelvic area before following their suggested treatment algorithm for sciaticalike retro-trochanteric pain. Level of evidence II.
|Background: Videoconferencing on mobile phones may enhance communication, but knowledge on its quality in various situations is needed before it can be used in medical emergencies. Mobile phones automatically activate loudspeaker functionality during videoconferencing, making calls particularly vulnerable to background noise. The aim of this study was to investigate if videoconferencing can be used between lay bystanders and Emergency Medical Dispatch (EMD) operators for initial emergency calls during medical emergencies, under suboptimal sound and light conditions. Methods: Videoconferencing was tested between 90 volunteers and an emergency medical dispatcher in a standardized scenario of a medical emergency. Three different environments were used for the trials: indoors with moderate background noise, outdoors with daylight and much background noise, and outdoors during nighttime with little background noise. Thirty participants were recruited for each of the three locations. After informed consent, each participant was asked to use a video mobile phone to communicate with an EMD operator. During the video call the EMD operator gave instructions for tasks to be performed by the participant. The video quality from the caller to the EMD was evaluated by the EMD operator and rated on a five step scale ranging from "not able to see" to "good video quality". Sound quality between participants and EMD operators was assessed by a method developed for this trial. Kruskal – Wallis and Chi-square tests were used for statistical analysis. Results: Video quality was significantly different between the groups (p <0.001), and the nighttime group had lower video quality. For most sessions in the nighttime group it was still possible to see actions done at the simulated emergency site. All participants were able to perform their tasks according to the instructions given by dispatchers, although with a need for more repetitions during sessions with much background noise. No calls were rated by dispatchers as incomprehensible due to low sound quality and only 3% of the calls were considered somewhat difficult or very difficult to understand. Conclusions: Videoconferencing on mobile phones can be used for the initial emergency call during medical emergencies also in suboptimal conditions.
|Increased glomerular filtration rate (GFR), also called hyperfiltration, is a proposed mechanism for renal injury in diabetes. The causes of hyperfiltration in individuals without diabetes are largely unknown, including the possible role of borderline hyperglycemia. We assessed whether impaired fasting glucose (IFG; 5.6–6.9 mmol/L), elevated HbA1c, or hyperinsulinemia are associated with hyperfiltration in the general middle-aged population. A total of 1,560 individuals, aged 50–62 years without diabetes, were included in the Renal Iohexol Clearance Survey in Tromsø 6 (RENIS-T6). GFR was measured as single-sample plasma iohexol clearance. Hyperfiltration was defined as GFR >90th percentile, adjusted for sex, age, weight, height, and use of renin-angiotensin system inhibitors. Participants with IFG had a multivariable-adjusted odds ratio of 1.56 (95% CI 1.07–2.25) for hyperfiltration compared with individuals with normal fasting glucose. Odds ratios (95% CI) of hyperfiltration calculated for a 1-unit increase in fasting plasma glucose (FPG) and HbA1c, after multivariable-adjustment, were 1.97 (1.36–2.85) and 2.23 (1.30–3.86). There was no association between fasting insulin levels and hyperfiltration. A nonlinear association between FPG and GFR was observed (df = 3, P < 0.0001). GFR increased with higher glucose levels, with a steeper slope beginning at FPG ≥5.4 mmol/L. Borderline hyperglycemia was associated with hyperfiltration, whereas hyperinsulinemia was not. Longitudinal studies are needed to investigate whether the hyperfiltration associated with IFG is a risk factor for renal injury in the general population.
|Introduction We recently demonstrated that intravenously
infused recombinant human activated protein C (APC)
attenuates ovine lipopolysaccharide (LPS)-induced lung injury.
In this study, our aim was to find out whether treatment with
inhaled aerosolised APC (inhAPC) prevents formation of
increased lung densities and oedema and derangement of
oxygenation during exposure to LPS.
Methods: Sheep were anaesthetised during placement of intravascular introducers. After one to four days of recovery from instrumentation, the animals were re-anaesthetised, endotracheally intubated and mechanically ventilated throughout a six-hour experiment where the sheep underwent quantitative lung computed tomography. Sheep were randomly assigned to one of three groups: a sham-operated group (n = 8) receiving inhaled aerosolised saline from two hours after the start of the experiment; a LPS group (n = 8) receiving an intravenous infusion of LPS 20 ng/kg per hour and, after two hours, inhaled aerosolised saline over the next four hours; a LPS+inhAPC group (n = 8) receiving an intravenous infusion of LPS 20 ng/kg per hour and, after two hours, aerosolised APC 48 µg/kg per hour inhaled throughout the experiment. Data were analysed with analysis of variance; P less than 0.05 was regarded as significant.
Results: An infusion of LPS was associated with a reduction of well-aerated lung volume and a rapid fall in arterial oxygenation that were both significantly antagonised by inhaled APC. Pulmonary vascular pressures and extravascular lung water index increased significantly during exposure to LPS, but inhaled APC had no effect on these changes.
Conclusions: Inhalation of aerosolised APC attenuates LPSinduced lung injury in sheep by preventing a decline in the volume of aerated lung tissue and improving oxygenation.
|Background Blunt implementation of Western trauma system models is not feasible in low-resource communities with long prehospital transit times. The aims of the study were to evaluate to which extent a low-cost prehospital trauma system reduces trauma deaths where prehospital transit times are long, and to identify specific life support interventions that contributed to survival. Methods In the study period from 1997 to 2006, 2,788 patients injured by land mines, war, and traffic accidents were managed by a chain-of-survival trauma system where non-graduate paramedics were the key care providers. The study was conducted with a time-period cohort design. Results 37% of the study patients had serious injuries with Injury Severity Score ≥ 9. The mean prehospital transport time was 2.5 hours (95% CI 1.9 - 3.2). During the ten-year study period trauma mortality was reduced from 17% (95% CI 15 -19) to 4% (95% CI 3.5 - 5), survival especially improving in major trauma victims. In most patients with airway problems, in chest injured, and in patients with external hemorrhage, simple life support measures were sufficient to improve physiological severity indicators. Conclusion In case of long prehospital transit times simple life support measures by paramedics and lay first responders reduce trauma mortality in major injuries. Delegating life-saving skills to paramedics and lay people is a key factor for efficient prehospital trauma systems in low-resource communities.
|Background: Studies on the effect of organizational factors on the involuntary admission of psychiatric patients have been few and yielded inconclusive results. The objective was to examine the importance of type of service-system, level of care, length of inpatient stay, gender, age, and diagnosis on rates of involuntary admission, by comparing one deinstitutionalized and one locally institutionalized service-system, in a naturalistic experiment. Methods: 5538 admissions to two specialist psychiatric service-areas in North Norway were studied, covering a four-year period (2003-2006). The importance of various predictors on involuntary admission were analyzed in a logistic regression model. Results: Involuntary admission to the services was associated with the diagnosis of psychosis, male sex, being referred to inpatient treatment, as well as type of service-system. Patients from the deinstitutionalized system were more likely to be involuntarily admitted. Conclusions: Several factors predicted involuntary status, including male sex, the diagnosis of psychosis, and type of service-system. The results suggests that having psychiatric beds available locally may be more favourable than a traditional deinstitutionalized service system with local outpatient clinics and central mental hospitals, with respect to the use of involuntary admission.
|Introduction: Arginine vasopressin (AVP) is increasingly used to restore mean arterial pressure (MAP) in low-pressure shock states unresponsive to conventional inotropes. This is potentially deleterious since AVP is also known to reduce cardiac output by increasing vascular resistance. The effects of AVP on blood flow to vital organs and cardiac performance in a circulation altered by cardiac ischemia are still not sufficiently clarified. We hypothesised that restoring MAP by low dose, therapeutic level AVP would reduce vital organ blood flow in a setting of experimental acute left ventricular dysfunction. Methods: Cardiac output (CO) and arterial blood flow to the brain, heart, kidney and liver were measured in nine pigs using transit-time flow probes. Left ventricular pressure-volume catheter and central arterial and venous catheters were used for haemodynamic recordings and blood sampling. Transient left ventricular ischemia was induced by intermittent left coronary occlusions resulting in a 17% reduction in cardiac output and a drop in MAP from 87 ± 3 to 67 ± 4 mmHg (p < 0.001). A low-dose therapeutic level of AVP (0.005 U/kg/min) was used to restore MAP to pre-ischemic values (93 ± 4 mmHg). Results: AVP further impaired systemic perfusion (CO and brain, heart and kidney blood flow reduced by 29, 18, 23 and 34%, respectively) due to a 2.0-, 2.2-, 1.9- and 2.1-fold increase in systemic, brain, heart and kidney specific vascular resistances. The hypoperfusion induced by AVP was associated with an increased systemic oxygen extraction. Oxygen saturation in blood drawn from the great cardiac vein fell from 29 ± 1 to 21 ± 3% (p = 0.01). Finally, these effects were reversed 40 min after AVP was withdrawn. Conclusion: Low dose AVP induced a pronounced reduction in vital organ blood flow in pigs after transient cardiac ischemia. This indicates a potentially deleterious effect of AVP in patients with heart failure or cardiogenic shock due to impaired coronary perfusion.
|Recent studies from Italy, Japan and Norway have confirmed previous reports, which found that a large variety of palliative radiotherapy regimens are used for painful bone metastases. Routine use of single fraction treatment might or might not be the preferred institutional approach. It is not entirely clear why inter-physician and interinstitution differences continue to persist despite numerous randomized trials, meta-analyses and guidelines, which recommend against more costly and inconvenient multi-fraction regimens delivering total doses of 30 Gy or more in a large number of clinical scenarios. In the present mini-review we discuss the questions of whether doctors are ignoring evidence-based medicine or whether we need additional studies targeting specifically those patient populations where recent surveys identified inconsistent treatment recommendations, e.g. because of challenging disease extent. We identify open questions and provide research suggestions, which might contribute to making radiation oncology practitioners more confident in selecting the right treatment for the right patient.
|Aims. To evaluate whether reduced waiting time influences survival of patients treated with whole-brain radiotherapy (WBRT) for brainmetastases. Materials and Methods. Retrospective intention-to-treat study including 110 patients treated with primary WBRT (typically 10 fractions of 3Gy; no other treatment between diagnosis and WBRT). Uni- and multivariate tests were performed. Results. Median delay between imaging diagnosis and WBRT was 12 days (range 0–66 days).WBRT started within 1 week in 36%, during the second week in 28%, and during the third week in 18% of patients. No significant correlation between waiting time and survival was evident, except for one subgroup of patients. Those without extracranial metastases (potentially more threatened by worse intracranial disease control) survived for a median of 2.5 months from WBRT if waiting time was 2 weeks or longer as compared to 5.6 months if waiting time was shorter than 2 weeks (𝑃� = 0.03). The same correlation was seen if survival was computed from imaging diagnosis. Conclusion. If departmental resources are not sufficient to provide immediate WBRT within 2 weeks to all patients, those without extracranial metastases should be prioritised.This study did not address the impact of waiting time on quality of life or symptom palliation.
|Different approaches can be chosen to quantify the impact and merits of scientific oncology publications. These include source of publication (including journal reputation and impact factor), whether or not articles are cited by others, and access/download figures. When relying on citation counts, one needs to obtain access to citation databases and has to consider that results differ from one database to another. Accumulation of citations takes time and their dynamics might differ from journal to journal and topic to topic. Therefore, we wanted to evaluate the correlation between citation and download figures, hypothesising that articles with fewer downloads also accumulate fewer citations. Typically, publishers provide download figures together with the article. We extracted and analysed the 50 most viewed articles from 5 different open access oncology journals. For each of the 5 journals and also all journals combined, correlation between number of accesses and citations was limited (r = 0.01-0.30). Considerable variations were also observed when analyses were restricted to specific article types such as reviews only (r = 0.21) or case reports only (r = 0.53). Even if year of publication was taken into account, high correlation coefficients were the exception from the rule. In conclusion, downloads are not a universal surrogate for citation figures.
|Background: Prognostic scores might be useful tools both in clinical practice and clinical trials,
where they can be used as stratification parameter. The available scores for patients with brain
metastases have never been tested specifically in patients with primary breast cancer. It is therefore
unknown which score is most appropriate for these patients.
Methods: Five previously published prognostic scores were evaluated in a group of 83 patients with brain metastases from breast cancer. All patients had been treated with whole-brain radiotherapy with or without radiosurgery or surgical resection. In addition, it was tested whether the parameters that form the basis of these scores actually have a prognostic impact in this biologically distinct group of brain metastases patients.
Results: The scores that performed best were the recursive partitioning analysis (RPA) classes and the score index for radiosurgery (SIR). However, disagreement between the parameters that form the basis of these scores and those that determine survival in the present group of patients and many reported data from the literature on brain metastases from breast cancer was found. With the four statistically significant prognostic factors identified here, a 3-tiered score can be created that performs slightly better than RPA and SIR. In addition, a 4-tiered score is also possible, which performs better than the three previous 4-tiered scores, incl. graded prognostic assessment (GPA) score and basic score for brain metastases (BSBM).
Conclusion: A variety of prognostic models describe the survival of patients with brain metastases from breast cancer to a more or less satisfactory degree. However, the standard brain metastases scores might not fully appreciate the unique biology and time course of this disease, e.g., compared to lung cancer. It appears possible that inclusion of emerging prognostic factors will improve the results and allow for development and validation of a consensus score for broad clinical application. The model that is based on the authors own patient group, which is not large enough to fully evaluate a large number of potential prognostic factors, is meant to illustrate this point rather than to provide the definitive score.
|We evaluated the performance of the new 4-tiered melanoma-specific graded prognostic assessment (GPA) score and the previously published general GPA score in patients with brain metastases from malignant melanoma managed with different approaches including best supportive care. Materials and Methods: Retrospective analysis of 51 patients. Compared with the original analysis of the melanoma-specific GPA score, these patients were more representative of the general population of patients with brain metastases from this disease. The present data confirmed that both scores identify patients with favorable prognosis who might be candidates for focal treatments. However, survival in the 2 unfavorable prognostic subgroups defined by the melanoma-specific GPA was not significantly different. Median survival in the melanoma-specific GPA classes was 3.1, 3.7, 7.5, and 12.7 months. Karnofsky performance status (KPS) and serum lactatdehydrogenase (LDH) level significantly predicted survival. In order to select the right patient to the right treatment and avoid overtreatment and suboptimal resource utilization in patients with very limited survival, improved prognostic tools are needed. The melanoma-specific GPA does not include extracranial disease extent or surrogate markers such as LDH. We suggest that a combination of KPS <70 and elevated LDH might better predict short survival than any of the GPA scores. This hypothesis should be confirmed in larger studies.
|Background: This review addresses the strengths and weaknesses of 6 different prognostic
indices, published since the Radiation Therapy Oncology Group (RTOG) developed and validated
the widely used 3-tiered prognostic index known as recursive partitioning analysis (RPA) classes,
i.e. between 1997 and 2008. In addition, other analyses of prognostic factors in groups of patients,
which typically are underrepresented in large trials or databases, published in the same time period
are reviewed.
Methods: Based on a systematic literature search, studies with more than 20 patients were included. The methods and results of prognostic factor analyses were extracted and compared. The authors discuss why current data suggest a need for a more refined index than RPA.
Results: So far, none of the indices has been derived from analyses of all potential prognostic factors. The 3 most recently published indices, including the RTOG's graded prognostic assessment (GPA), all expanded from the primary 3-tiered RPA system to a 4-tiered system. The authors' own data confirm the results of the RTOG GPA analysis and support further evaluation of this tool.
Conclusion: This review provides a basis for further refinement of the current prognostic indices by identifying open questions regarding, e.g., performance of the ideal index, evaluation of new candidate parameters, and separate analyses for different cancer types. Unusual primary tumors and their potential differences in biology or unique treatment approaches are not well represented in large pooled analyses.
|The important role of combined chemoradiation for several groups of patients with nonsmall cell lung cancer (NSCLC) is reflected by the large number of scientific articles published during the last 30 years. Different measures of impact and clinical relevance of published research are available, each with its own pros and cons. For this review, article citation rate was chosen. Highly cited articles were identified through systematic search of the citation database Scopus. Among the 100 most often cited articles, meta-analyses (nD5) achieved a median of 203 citations, guidelines (nD7) 97, phase III trials (nD29) 168, phase II trials (nD21) 135, phase I trials (nD7) 88, and others combined 115.5 (p D0.001). Numerous national and international cooperative groups and several single institutions were actively involved in performing often cited, high-impact trials, reflecting the fact that NSCLC is a world-wide challenge that requires research collaboration. Platinum-containing combinations have evolved into a standard of care, typically administered concurrently.The issue of radiotherapy fractionation and total dose has also been studied extensively, yet with less conclusive results. Differences in target volume definition have been addressed. However, it was not possible to test all theoretically possible combinations of radiotherapy regimens, drugs, and drug doses (lower radiosensitizing doses compared to higher systemically active doses).That is why current guidelines offer physicians a choice of different, presumably equivalent treatment alternatives. This review identifies open questions and strategies for further research.
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Midwest Locations
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Profound Historical Youth
Join Date: Apr 2012
Posts: 1,238
I don't mean to spam, but here's another post.
Locations near St. Louis, MO:
~Botanical Gardens in St. Louis. Has everything from tropical plants to Victorian gardens to a Japanese one.
~Forest Park. It's bigger than Central Park, and has TONS of beautiful and fun places to take pictures. There's the zoo, the Jewel Box greenhouse, Art Hill, the Art Museum (which was a building from the 1904 World's Fair, so it'd look great for Edwardian/Victorian cosplays) the History museum, lovely park trails, the Science Center/Planetarium, (Good for futuristic/sci-fi cosplays...hell, the Planetarium was one of the main locations in the derpy 2006 sci-fi movie Black Hole.) and all sorts of other wonders. How much are all these? Almost everything in that park is FREE.
~The City Museum. Bring a flashlight for the caves, cosplay repair kit, and first aid kit. If you leave with a few bruises, you had fun.
~The Arch grounds get you a nice view of the Mississippi River.
~Castlewood State Park. Nice riverside beaches, secluded, quiet, and lots of flora.
~Historic St. Charles. Has the nice historic small town feel.
~Laumeier Sculpture Park. You can climb on certain statues, and even the natural woods look like a work of art.
Other MO locations:
~Mermac Caverns. One of the caves rooms used to be a freaking ballroom, so you'd have plenty of room in there for whatever.
~Lake of the Ozarks. It's beautiful.
~Various farms can be really pretty. Just get permission before you step on anyone's land. I think that most farm owners would be flattered that you think their farm is so pretty that you want to take pictures on it!
~St. Genevieve. It's a small city but has a LOVELY historical/small town charm that makes it so pretty.
IL locations:
~Cahokia Mounds. Ancient Native American ruins that look pretty cool.
~Lake Carlisle. Nice lakeside beaches.
~Somewhere on the coast of Lake Michigan and various parks in Chicago. (Last time I went I was in 3rd grade, so I can't remember anything about that city.)
~Various farms. (With permission! Trespassing charges are no fun!)
My username is an incredibly stupid pun that only I will get.
Currently working on:
Momoko Koigakubo -- Ghost Stories (Dub)
Scarlett O'Hara Drapery Dress -- Gone With the Wind
Deandra -- MPGiS
Anna Cornonation Dress -- Frozen
Vader Eloha/The Queen -- OFF
Princess Suwa -- Mascot of the city of Suwa, Japan
My favorite cosplays:
Brittnay Matthews -- MPGiS
Mom Lalonde -- Homestuck
Princess Kenny -- South Park
Last edited by EvilLittleKiss : 10-06-2012 at
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Book your room at Quay West Suites Melbourne
Queen Studio SuiteMax Occupancy: 2 guests (up to 1 child)
King Studio SuiteMax Occupancy: 2 guests (up to 1 child)
Deluxe One Bedroom SuiteMax Occupancy: 3 guests (up to 2 children)
Deluxe One Bedroom Suite - River ViewMax Occupancy: 3 guests (up to 2 children)
Premium One Bedroom Suite - City ViewMax Occupancy: 3 guests (up to 2 children)
Superior One Bedroom SuiteMax Occupancy: 3 guests (up to 2 children)
5-star luxury aparthotel in Southbank near Federation Square
This luxury aparthotel is located in the heart of Southbank, walking distance from Hamer Hall, Federation Square, and Eureka Tower. Also nearby are Crown Casino and National Gallery of Victoria.
Property Features
In addition to a restaurant, Quay West Suites Melbourne features an indoor pool. Other amenities include a bar/lounge and a conference center.
Room Amenities
Televisions come with cable channels. Guestrooms also feature kitchens, sofa beds, and refrigerators.Information missing or incorrect? Tell us!
At your hotel
At your hotel
In addition to an indoor pool, Quay West Suites Melbourne provides a spa tub, a sauna, and a fitness center. The aparthotel offers a restaurant. A bar/lounge is on site where guests can unwind with a drink. A computer station is located on site and high-speed wired and wireless Internet access is available for a surcharge.
This 5-star property offers access to a business center, limo/town car service, and meeting rooms. Event facilities measuring 4304 square feet (400 square meters) include a conference center and conference space. This luxury aparthotel also offers a rooftop terrace, multilingual staff, and a garden. For a surcharge, a roundtrip airport shuttle (available on request) is offered to guests. Onsite parking is available (surcharge).
Quay West Suites Melbourne has designated areas for smoking.
- 24-hour front desk
- Babysitting or childcare (surcharge)
- Airport transportation (surcharge)
- Total number of rooms - 114
- Number of floors - 15
- Bar/lounge
- Conference space size (meters) - 400
- Complimentary newspapers in lobby
- Conference space
- Dry cleaning/laundry service
- Elevator/lift
- Express check-out
- Fitness facilities
- Designated smoking areas
- Beach/pool umbrellas
- Computer station
- Rooftop terrace
- Luggage storage
- Express check-in
- Business center
- Laundry facilities
- Limo or Town Car service available
- Meeting rooms
- Multilingual staff
- Valet parking (surcharge)
- Garden
- Picnic area
- Porter/bellhop
- Restaurant
- Safe-deposit box at front desk
- Pool sun loungers
- Conference center
- Self parking (surcharge)
- Number of meeting rooms - 8
- Conference space size (feet) - 4304
- Sauna
- Number of buildings/towers - 1
- Spa tub
- Indoor pool
- Breakfast available (surcharge)
- Television in lobby
- Wedding services
- Wireless Internet access - surcharge
- Wired (high-speed) Internet access - surcharge
Stay connected
Available in all rooms: Wireless Internet access (surcharge) , Wired internet access (29.00 AUD per 24 hours surcharge)
Available in some public areas: Wireless internet access (29.00 AUD per 24 hours surcharge), Wired (high-speed) Internet access - surcharge
Park your car
Self parking (surcharge), Valet parking (surcharge)
In your room
- DVD player
- Balcony
- Separate sitting area
- Air conditioning
- Climate control
- Blackout drapes/curtains
- Microwave
- Kitchen
- Refrigerator
- Minibar
- Coffee/tea maker
- Daily housekeeping
- Bathrobes
- Complimentary toiletries
- Hair dryer
- In-room massage available
- Slippers
- Shower/tub combination
- In-room childcare (surcharge)
- Desk
- Cable TV service
- Iron/ironing board
- In-room safe (laptop compatible)
- Sofa bed
- Rollaway/extra beds available
- Cribs/infant beds available
- Wireless Internet access (surcharge)
- Wired high-speed Internet access (surcharge)
- Complimentary newspaper
- Room service (24 hours)
Eat and drink
Buffet breakfasts are available for a surcharge and are served each morning between 6:30 AM and 10 AM.
Jarrah Restaurant - This restaurant specializes in local cuisine and serves breakfast and dinner. Guests can enjoy drinks at the bar. A children's menu is available. Happy hour is offered.
Late night fare is available from 24-hour room service.
An indoor pool and a spa tub are on site. Other recreational amenities include a sauna and a fitness center.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Bicycle rentals nearby
- Hiking/biking trails nearby
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
- In-room accessibility
- Roll-in shower
- Accessible parking
- Accessible path of travel
The fine print for Quay West Suites Melbourne
When you arrive
Check-in time starts at 2 PM
When you leave
Check-out time is 11 AM
How you can pay
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
24-hour check-in
- Breakfast fee: AUD 34.00 per person (approximately)
- Fee for in-room high-speed Internet (wired): AUD 29.00 (for 24 hours, rates may vary)
- Fee for wireless Internet in public areas: AUD 29.00 (for 24 hours, rates may vary)
- Self parking fee: AUD 20 per night
- Valet parking fee: AUD 30 per day (in/out privileges)
We should mention
This property's policy is to refuse certain bookings for the purpose of group events or parties, including pre-wedding stag/bachelor and hen/bachelorette parties.
National Rating
Official Australia STAR Rating provided by AAA Tourism Pty Ltd
AAA Tourism Pty Ltd assigns an official STAR Rating for accommodations in Australia. This Apartment Hotel property is rated 5 stars.


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Do you think Renaissance masterpieces are just boring, dusty paintings? Collage artist James Kerr doesn't - and proves it with his creation of a number of animated GIFs using works of the great masters.
Fun with the old masters
Submitted by Milica on Mon, 2014-08-25 06:53
Do you think Renaissance masterpieces are just boring, dusty paintings? Collage artist James Kerr doesn't - and proves it with his creation of a number of animated GIFs using works of the great masters.
Location of Llanllyr nunnery discovered in Wales
Submitted by Milica on Sun, 2014-08-24 14:40
Sometime in the late 12th century, Rhys ap Gruffudd founded a daughter house to the convent of Strata Florida in the Aeron Valley of wales. Researchers have known about the Llanllyr nunnery, but never its precise location - until now when excavations in Ceredigion have revealed the convent as well as a cemetery and Tudor mansion.
Rare Ethelbert penny found in Sussex field
Submitted by Milica on Sun, 2014-08-24 09:10
King Ethelbert II was murdered, possibly for minting his own coins. Now an extremely-rare, 8th century silver penny, found by metal detectorist Darrin Simpson, has been discovered in a Sussex, England field. (photo)
Remains of Black Shuck found in ruins of Leiston Abbey?
Submitted by Milica on Sat, 2014-08-23 15:49
An old legend in Suffolk, England, tells of a massive black dog, known as Black Shuck, which terrorized the village folk, and was the subject of a report in 1577 by the Reverend Abraham Fleming. Now archaeologists believe they have found the remains of a huge dog buried in the area. (photo)
Lincoln Castle reveals Saxon buried in his boots
Submitted by Milica on Sat, 2014-08-23 10:34
The UK£22 million renovtion of Lincoln Castle continues to unearth medieval treasures, this time with the discovery of a high-status Saxon burial in a church wall. The remains showed a powerful man, suffering from rickets, who was buried in his boots.
Shire of Blackhawk sponsors Newcomers' Night
On June 19, 2014, the Shire of Blackhawk, the local chapter of the Society for Creative Anachronism in Rockford, Illinois, invited those interested in the Middle Ages to join them at the Northwest Community Center's Corbett Building for hands-on activities practiced by the group. The Rock River Times published the invitation. (photo)
Vindolanda Nero coin "a special find"
Submitted by Milica on Thu, 2014-08-21 17:03
Archaeologists working at Vindolanda, the Roman fort in northeastern England, made a "special" find recently: a rare gold coin bearing the image of Roman emperor Nero, the first gold coin found during the excavation's 40-year history. (photo)
"Holy Grail" stolen in Wales
Submitted by Milica on Thu, 2014-08-21 13:19
The Nanteos Cup is missing. Rumored to be the Holy Grail, brought to Britain by Joseph of Arimathea, the olive wood cup is normally kept in a bank vault in Wales, but was loaned to an ailing women in Weston-Under-Penyard. It was stolen from her home July 14, 2014. (photo)
Remains of Henry VII of Luxembourg buried with rare silk cloth
Submitted by Milica on Wed, 2014-08-20 20:19
Researchers in Italy have the rare opportunity to examine and analyze the remains of Henry VII of Luxembourg, German king and Holy Roman emperor, who died in 1313 and is buried in Pisa Cathedral. The remains were exhuned in 2013 to determine the emperor's physical features and cause of death. (photos)
"What's Up" with A&S in Drachenwald?
Submitted by Milica on Wed, 2014-08-20 11:31
For issue 8 of What's Up Wednesday, the A&S blog for the Kingdom of Drachenwald, the topic is sewing, featuring some amazing projects created by artisans of the Kingdom.
Newstead Abbey to receive grant from World Monuments Fund
Submitted by Milica on Tue, 2014-08-19 20:25
In 1540, the Byron family, ancestors of the famous Lord Byron, was given Newstead Abbey near Nottingham, England. Built in the 12th century, the abbey has since fallen into disrepair, and it has become the recipient of UK£40,000 from the World Monuments Fund to save the crumbling structure.
Viking amulet features detailed dress
Submitted by Milica on Tue, 2014-08-19 10:23
Experts in Denmark are intrigued by the recent discovery of a Viking Age amulet/figurine by a metal detectorist in a field near Revninge. The small silver figurine, possibly representing Freya the goddess of fertility, wears a marvelously-detailed Viking dress. (photo)
Medieval sewer system found at Drum Castle
Submitted by Milica on Mon, 2014-08-18 15:12
Archaeologists working on a dig at Drum Castle in Aberdeenshire, Scotland, have discovered the remains of the medieval sanitation system which once surrounded the 14th-century Tower of Drum.
Lilies War 28 photos online
Submitted by Milica on Mon, 2014-08-18 10:30
Sofya reports that a number of photo albums from Lilies War 28 are now available on the Calontiri website.
Mirabel de Malmesberie elevated to Laurel in the Outlands
Submitted by Milica on Sat, 2014-08-16 13:51
Kaliyan Kali reports that at Their Caer Galen Defender event, Their Majesties Walrick and Cecilia, of the Kingdom of the Outlands, offered elevation to the Order of the Laurel to the Honorable Lady Mirabel de Malmesberie.
Earliest case of Down syndrome diagnosed in French skeleton
Submitted by Milica on Sat, 2014-08-16 09:13
A team of archaeologists at the University of Bordeaux has identified the earliest known case of Down syndrome in the remains of a child who lived in 6th century France. The diagnosis was made after the remains were submitted to a (CT) scan.
Mystery of Wolsey's missing angels solved
Submitted by Milica on Fri, 2014-08-15 21:10
Once upon a time, four bronze angels adorned the gateposts of the Wellingborough Golf Club in Northamptonshire, England. No one paid much attention to them until two were stolen, but now all four, identified as Renaissance treasures, are the subject of a fundraising effort by the Victoria and Albert Museum. (photo)
The Known World Arts & Sciences display at Pennsic
Submitted by SleepyUnicorn on Fri, 2014-08-15 19:30
SleepyUnicorn has posted a photo album from the Known World A&S Display held at Pennsic 43.
Oldest copy of "The Brus" restored
Submitted by Milica on Thu, 2014-08-14 17:15
The oldest known copy of "The Brus," an epic poem describing the Battle of Bannockburn, has been restored in time for the 700th celebration of the event. The poem was written in 1375 by the Archdeacon of Aberdeen. (photos)
Chaninai al-Zarqa' bint Ibrahim ibn Rashid elevated to Pelican in the West
Gillian reports that Their Majesties Conor and Isa of the Kingdom of the West have chosen to elevate her protégé, Chaninai al-Zarqa' bint Ibrahim ibn Rashid, to the Order of the Pelican.
Shishido Tora Gozen elevated to Pelican in AEthelmearc
Submitted by Milica on Thu, 2014-08-14 11:29
In June 2014, Their Majesties Tindal and Etain of the Kingdom of AEthelmearc offered elevation to the Order of the Pelican to Shishido Tora Gozen. The elevation too place at the Kingdom's Equestrian Championship.
Brennos Agrocunos knighted in the West
Submitted by Milica on Wed, 2014-08-13 12:46
Morucatha reports that, at the recent West-An Tir War, Their Majesties Conor and Isa of the Kingdom of the West offered elevation to the Order of the Chivalry to Brennos Agrocunos.
The SCA is now on AmazonSmile
Submitted by Milica on Wed, 2014-08-13 08:24
Many of us shop at Amazon for a wide range of products. Did you know that the SCA can benefit from each purchase you make at no additional charge to you?
Viking sword has colorful history
Submitted by Milica on Tue, 2014-08-12 18:01
Auctioneers at Christie's have announced that they will offer for auction a double-edged Viking sword associated with the battles of Hastings, Stamford Bridge and Bannockburn. The sword is expected to bring between UK£80,000 to £120,000. (photo)
Pól the Pelican is cheered in Wales
Submitted by Gossip on Tue, 2014-08-12 14:18
Barun Pól O'Briain was yesterday elevated to the Order of the Pelican by the King and Queen of Drachenwald. Under threatening skies at Raglan Castle in Wales the two-time Viceroy of Insulae Draconis was made a peer before a tearful crowd of his noble friends and well-wishers.
SCA: A game of flashing weaponry, handmade crafts and occasional camping under the stars
Submitted by Milica on Tue, 2014-08-12 13:38
"Every time I come, it's like the highlight of my life. It's addictive. Especially if you're an adrenaline junkie," said fencer Susan Woodard about a recent fighter practice held at Roosevelt Park in Longmont, Colorado. Woodard spoke with Scott Rochat of the Times-Call about the SCA and the Barony of Caer Galen. (photos and video)
SCA Audit Team
Submitted by Milica on Mon, 2014-08-11 15:16
The State of California is requiring a full financial audit from the SCA. We have contracted with the CPA firm of Boman Accounting Group, Inc. to conduct the audit for the years 2012 and 2013 and report their findings.
New Laurel King of Arms named
Submitted by Milica on Mon, 2014-08-11 11:40
Current SCA Laurel King of Arms, Meistari Gabriel Kjotvason, reports that Andrewe Bawldwyn has been named to take over the position as head of the College of Arms.
Committee on SCA Chirurgeonate sought by BoD
Submitted by Milica on Mon, 2014-08-11 07:53
The Board of Directors of the Society for Creative Anachronism is seeking members for a committee concerning the Chirurgeonate.
Medieval bath found in Shkodër excavations
Submitted by Milica on Sun, 2014-08-10 12:55
An archaeological team from the Antiquity of Southeastern Europe Research Centre of the University of Warsaw, Poland has discovered a 14th century bath in northwestern Albania. The structure combines technologies of the Roman and Ottoman Empires.
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