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Feuerstein's Biotech-Stock Mailbag
Thanks for returning to the Biotech Mailbag, where I try my best to answer your biotech investment questions. This week, I'll focus on Cell Genesys (CEGE), Encysive Pharmaceuticals (ENCY), Gilead Sciences (GILD) and Alexion Pharmaceuticals (ALXN).
I'll kick off the action with a note from Dore S., who writes: "Hey Adam, your faithful herd would probably appreciate an update on Cell Genesys. The company released a Feb. 15 press release that smelled like a subset analysis but has catapulted the stock. Your two cents for all to read would be appreciated."
Dore's sense of smell is pretty good. I'm
Pfizer's (PFE)
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Things Are Settling Down - For Me!
... you imagine dining al fresco on November 4? We had to wait for the paella too long but the 2 for 1 sangrias helped pass the time.
Richard is off to Lowes for a drill so we can make the guest bed, hang the paper towels, complete our desk etc., and finally I can use a laptop to edit these entries. The iPad is difficult I find. However, I still have to load some pictures. Stay ...
Williston, FL
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As we were driving near Ocala on I-75, we noticed Don Garlits' Museum of Drag Racing, so we drove there on Friday.
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Home Sweet Home
After a stop at the Florida Welcome Centre for a map and a drink of juice we drove into Florida! Our destination was 28 degrees, 50 minutes and 23 seconds north, 82 degrees, 00 minutes and 05 seconds west a.k.a.1964 Somerset Ave. - altitude 70 - 100 feet depending upon the day.
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Isaac is coming close and we HAVE to know!
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The weather channel is the place to be in these matters. Current (local) weather updates are followed by short documentaries of weather disasters and than again by the updates on the storm Isaac. It's incredible how much they can tell you about this storm, all of the weather systems around this, what the risks are, what to do, what not to do... and that 24/7. If you watch the ...

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Dec 11, 2011; Detroit, MI, USA; Detroit Lions tight end Brandon Pettigrew (87) is announced before the game against the Minnesota Vikings at Ford Field. Tim Fuller-US PRESSWIRE
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Sony's head of hardware development for both the PS3 and the PSP, Izumi Kawanishi, sat down with Famitsu magazine to discuss the details of the plaguing question: what's with the connectivity between the PS3 and the PSP... game-wise? Clearly, just viewing the media wouldn't be enough, so... there's got to be more to it than that. Says IGN: "While Kawanishi didn't get into specifics, we imagine the PSP being used just to display game footage sent to it by the PS3 and send back controller data input by the player." Yeah, well, if that isn't a revelation, here's a bit of foresight: Kawanishi purposely created the PSP with a 16:9 display because he had this idea for the future in mind. Good job, Izumi-chan. Can we say that? Of course, you need the 60GB Wi-Fi model of the PS3 to take advantage of this connectivity. Kawanishi didn't really go into whether a USB Wi-Fi connection with the lower-end model will yield the same result, but really, why wouldn't it?
In a similar but mostly unrelated vein, updating your system software will be done via flash media or game/media software -- similar to the PSP system updates. Kawanishi made mention also that the PS3 games will indeed be region-free, so they can be played as-is (although there will be "exceptions"...). So there you have it -- a few questions answered, a couple left. Any plaguing you in particular? We'll keep an eye out for certain ones that pop up often.
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I do love it too, but I hold on for dear life
Join Date: Mar 2007
Posts: 1,278
awww thanks for posting paula,it looks fab !
Oct 2006 - Daytrip - Berny Riviere
July 2007 - Daytrip - Berny Riviere
Aug 2008 - 4 days - Adagio Aparthotel
Dec 2008 - 2 days - Explorers
Oct 2009 - Daytrip - Berny Riviere
Oct 2010 - 2 days - Le Chene Gris
Feb 2011 - Daytrip (using the SUN hoppers) Adagio Aparthotel
March 2012 - Daytrip (using SUN hoppers )The Kyriad
in planning : October 2012 using the Sky free tickets
Join Date: Aug 2008
Location: Isle of Man
Posts: 217
Love the WALL.E photo
Anne xxx
2008 Off-site: I-Drive (never again!)
2007 Caribbean Beach Resort
Join Date: Jul 2001
Location: scotland
Posts: 92
Day 7
Today we are using the last of our eBay tickets, and park hopping to see what we have missed thus far.
We decide to split up for the morning and meet at the rondez vous des stars for lunch. Shannon and I head for the Disneyland park and ady and Emma the movie studios, from this point I can only tell you what we got up to.
We headed straight for dumbo this morning to try and ride that first, this was the only ride I saw anywhere in the park with a queue again grrrrr, we pass on this and go and do the teacups, twice, Shannon loves this one lol, the carousel next, Peter pan (which she thought was going to be like crush and have a big drop) back to the t cups and then its a small world.
I asked her what she would like to do next and she said POTC, so we did that twice (had to force myself you know *ahem*) then on to buzz .where my 4 year old beat me .oh the shame!!!! So we went back on I stole the spin control and I won
I decided to go look for some characters now as apart from café Mickey we hadnt seen very many; I headed back to where we had been before (in front of the cookout restaurant?) and not a character in sight, then I saw a path ahead so went a wander down it and found woodys roundup, and we also found Halloween decorations woohooo. I was so pleased they started to put these up and I would like to have been there when they started the parades (I must remember that lottery ticket!!!).
We head into Woodys and we find Jesse, Shannon whips out her autograph book and gets in line, she is delighted to meet Jesse and is looking for woody, alas no sign of woody (woody is her absolute favourite Disney character followed by wall-e and remmy) she however throws herself with gusto at Jesse and nearly knocks her over with the force of her hug. We just finish with Jesse and Minnie appears and goes into her little house, the picture I got here was one of my favourites of the holiday I have it as my screensaver.
We wander around roundup for a bit and take pics of Shannon on bulls eye and with stinky Pete, and head out again to see characters out front, more or less the same ones as as had been there the day before, but wait, there are more coming
minnie-my favorite trip picture
out .ohhhhhhhhh eeyore and tiger, Shannons hand is grabbed and we are off at a gallop, and get there first result, eeyore first (he is my absolute favourite) and I manage to get someone to take a picture of us both with him. Then we turn to tiger, he has his back to me and I try to catch his tail, he turns round and gives me his best tiger beady eyed look and wags his finger at me Shannon cracks up lol. We wait and wait (why oh why are people so rude and cant just wait their turn) and it is finally Shannons turn, when, I see this child about 11 years old, heading for tiger at a flat our run and he has not seen Shannon, I put my arm out to stop him and with the force of his speed, he goes straight on his bum (I did not mean to do this, just to stop him mowing down my child but I am fed up with all the pushing and shoving, at least us brits know how to queue and have manners) so on with the show tiger was a delight and I got lots of pics and he gave me a special cuddle too, wouldnt let me leave until he had one, so I made myself do it caus I was at Disney and everything you understand *ahem*.
We started to head for the park entrance to move to the movie park for lunch, and saw Donald and went to get a pic there, no joy he was just leaving.
We see chip and dale, daisy, micky, goofy and Pluto at the entrance of movies, but are nearly late and cant stop. (Apparently this is where the princesses are as well, so we missed that as well, next time though)
We meet ady and Emma, and head in for lunch, I loved it the food was really good in here; I forget how many times I went back up for more. I would go back here fro dinner anyday. I had pate and crusty bread to start, then garlic king prawns, chicken wings, beef buerginoin, with ratatouille and a creamy courgette dish, and tried a little of all the puddings .we waddled out of there and just wanted to sleep lol.
But no, we headed back to the Main Park and Emma and ady headed for Indy (it was shut the first day) and we did pirates, again lol. Then we all headed for the lion king and it was shut, I was disappointed as I really wanted to see this, they were doing a lot of filming while I was there though so might have been something to do with that .hey ho next time.
We headed back down the park and got a spot to wait for the parade near to small world. The parade was really good. Shannon at last saw and woody and was screaming WOODY WOODY WOOOOOODY at him and he must have heard (who didnt) and waved at her made her whole holiday, tiger was great on his bouncy legs great touch, and jasmine and snow white came and spoke with her. All in all we all loved the parade.
We went back to the movie studios and went to Animagique; I loved this show so much and was singing along with all the songs.
I went on RNRC 3 times and had to draw a line under it then as I was starting to loose my voice lol, the other went to TOT again and Shannon and I did cars and carpets. We went into cinemagique and played around in there for a while, and did a little shopping.
parade (i was filming and only got one pic)
and again
halloween decs
and more
shannon is in that pot peeping lol
one more
sports bar
We headed back to the main park for candlebration, which was ok, I think this show needs full darkness for the lights to really be effective, but Im glad I saw it.
We headed for DD and had a couple of beer and some hot dogs and fries for tea, and did lots of shopping, then headed back to the hotel where I did a little packing, got changed and me and ady headed back to DD to have a few drinks.
We came back on the last bus and hit the sack
Next up
More shopping and the long trek home
Cannot stop singing "Just like we dreeeeamed it"
Has a calming influence
Join Date: Jun 2007
Posts: 12,287
Wooo Hoo all those characters !
We did that too this past trip - coaster fiends went one way, us character stalkers went another
Feb 07 Santa Fe, Oct 07 Santa Fe, Nov 07 Cheyenne, June 08 Explorers, Oct 08 surprise upgrade to the Newport Bay Club! May 09 Magic Circus, Dec 09 Santa Fe VIP, Oct 10 Santa Fe "Cars stylee", March 11 St Patricks Day Santa Fe, Nov 11 Dream Castle bonfire and Christmas, June 12 Dream Castle 20th Dreams, Feb 13 Santa Fe & Dreams, April 14 Santa Fe Spring Festival Fun, December 14 HNY
Join Date: Jul 2001
Location: scotland
Posts: 92
It was more that there was more for her to do in disney, than that but I was very pleased at how many more characters we saw that morning
Join Date: Aug 2008
Location: Isle of Man
Posts: 217
The picture with Minnie is gorgeous
Anne xxx
2008 Off-site: I-Drive (never again!)
2007 Caribbean Beach Resort
Disney VIP
Anyone for haggis
Aren't we all a cagey lot
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Location: 6,800Km from our happy place
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You achieved so much on day 7. Cracking photos
Join Date: Jul 2001
Location: scotland
Posts: 92
Last Day
This is our last *sniff sniff* day before the long trek home
We had nothing really planned, just a wander around DD for last minute bits and pieces.
We *I* packed, and tidied up the room oh hello we had carpet
Had a huge breakfast, and made up some rolls for later on
Caught the pink bus, and it was quiet, must have been because most people were at the parks already.
We were going to go up in the balloon, but it was too windy so that was that idea out the window.
More shopping then lol, I bought a jack sparrow towel yum yum Johnny all wrapped around me when Im just outta the shower!!!
Two Disney mugs, one eeyore and one Mickey, a cup with a straw down the side for Shannon again with Mickey. Couple of pens, and a pair of Minnie boots for Shannon which were on sale and a Disney princess top also on sale.
Purse emptied we wandered around there was this random guy skiing around the place, who entertained us for a bit.
Then we went and put our hands in all the handprints at Planet Hollywood mine fitted Dudley Moore and Harrison ford.
We had a good look around the rainforest café, and this is on my to-do list for next time. Shannon spent a long time watching the fish while I shopped awesome!!!!
And she loved the crocodile had a hard time getting her away from it.
Time was up so we headed back to the hotel, and repacked, seeing as I had bought more, and went down to wait for the shuttle bus, which arrived on time. A wave to Disney on the way and we were on our way home
fish tank
the balloon we never got on
im a princess too
rainforrest snake
last pic at the hotel
tired before we start lol
im bad lol
The journey back seemed even longer than the one out, and we arrived safe and sound Aberdeen at the back of ten, sorted the kids beds and flaked.
I got a days shopping in Aberdeen and emptied primark (Orkney has nowhere for cheap kids clothes and mine is rough on hers so I dont mind throwing out a top that cost a couple of quid lol) and that was my money done lol.
We got the boat at 5pm and were back home at midnight.
That is the end of our epic journey, to recap, highlight of the trip .had to be Shannons face everytime she saw a character and the enthusiasm which they gave her , had tears in my eyes many times. My highlight playing around with tiger and my massive hug. Emmas highlight was just being there, as she had never been out of the UK before and of course TOT lol . I hope you enjoyed reading this, It took back many memories for me and mostly all of them good, so it seems to have done the job of sorting things in my head.
See you on the boards and thanks for all the kindness and support shown to me throughout my ramblings
Cannot stop singing "Just like we dreeeeamed it"
Has a calming influence
Join Date: Jun 2007
Posts: 12,287
Fabulous trip report Paula - the highs, the lows, the highers .
Loved reading it.
Feb 07 Santa Fe, Oct 07 Santa Fe, Nov 07 Cheyenne, June 08 Explorers, Oct 08 surprise upgrade to the Newport Bay Club! May 09 Magic Circus, Dec 09 Santa Fe VIP, Oct 10 Santa Fe "Cars stylee", March 11 St Patricks Day Santa Fe, Nov 11 Dream Castle bonfire and Christmas, June 12 Dream Castle 20th Dreams, Feb 13 Santa Fe & Dreams, April 14 Santa Fe Spring Festival Fun, December 14 HNY
I do love it too, but I hold on for dear life
Join Date: Mar 2007
Posts: 1,278
awww lovely end to your trip
we loved Rendez Vous Des Stars too ,back in Aug would def eat there again
lmao @ you hodling your arm out to that boy (and he went on his butt ! )
have to say i soooo dont blame you
lovely lovely pics thanks for sharing
Oct 2006 - Daytrip - Berny Riviere
July 2007 - Daytrip - Berny Riviere
Aug 2008 - 4 days - Adagio Aparthotel
Dec 2008 - 2 days - Explorers
Oct 2009 - Daytrip - Berny Riviere
Oct 2010 - 2 days - Le Chene Gris
Feb 2011 - Daytrip (using the SUN hoppers) Adagio Aparthotel
March 2012 - Daytrip (using SUN hoppers )The Kyriad
in planning : October 2012 using the Sky free tickets
Join Date: Jul 2001
Location: scotland
Posts: 92
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text: Chargers WR Keenan Allen potentially out for rest of th... Chargers WR Keenan Allen potentially out for rest of th... Jon Lester featured on this week's Sports Illustrated c... Jon Lester featured on this week's Sports Illustrated c... Marcus Mariota shines on Letterman Marcus Mariota shines on Letterman Bobby Petrino's unique bonus Bobby Petrino's unique bonus Louisville vs. FIU: Game time, live stream, TV coverage Louisville vs. FIU: Game time, live stream, TV coverage Close Tweet0 Share0 Comment0 Share0 Share0 Stumble It0 Print0 More SI Wire Browns rookie Ausar Walcott charged with attempted murder by John Otano Email Posted: Wed Jun. 26, 2013 Ausar Walcott has been charged with attempted murder. (David Dermer/Getty Images)Cleveland Browns rookie linebacker Ausar Walcott has been charged with attempted murder after he allegedly punched a man in Passaic, N.J., according to The Record. The Browns released Walcott later Wednesday.According to Detective Andrew White of the Passaic police, Walcott punched Derrick Jones, 24, in the head outside a gentlemen's club early Sunday morning. Jones, who lives in New York City, was hospitalized and remains in critical condition.Walcott was charged with first-degree attempted murder, second-degree aggravated assault and third degree endangering an injured victim. Walcott turned himself in to police and his bail has been set at $500,000. The Browns signed Walcott as an undrafted free-agent last month and said they are "aware of the situation."The former University of Virginia linebacker was suspended two years ago after he was arrested following an altercation at James Madison University. SI WIRE: Aaron Hernandez arrested, released by Pats Promoted Stories Tweet Story0 Share Story0 Comment0 More Share Story0 Share Story0 Stumble It0 Print0 Comments


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PG at Nearly 48???
Find a Conversation
PG at Nearly 48???
|Fri, 08-01-2003 - 6:46pm
Here's the scoop...I'll be 48 in October. DH and I have been TTC for 2 years. We married (my second) his first in 2001. I had a TR done late 2000 and after 1 1/2 yrs of ttc w/no luck we had an HSG done and found that one tube completely blocked and the other isn't perfect. We gave up on getting pg naturally and started to investigate other options like DE/IVF. We were going to go for a December cycle and then DH had an accident and broke leg/arm and I got sent off to another city with my job. After two months not TTC for obvious reasons, I came home for a weekend and we BD. I normally have a 26 day cycle and now I'm on CD 30 and have been feeling quessy for about a week. I just thought that I was running late but now I'm beginning to wonder if that weekend with all the saved up swimmers did the trick! It would have been around the time I should have "O"d but didn't feel anything like I normally do...what do ya think...I'm out of town again and haven't mentioned it to DH...I'm afraid to test because it always seemed to jinx it in the past.
|Mon, 08-25-2003 - 5:26pm
I've been looking for a post from you to see if you are pg?? Please let us know. I hope it was ++++ !!!
|Fri, 09-05-2003 - 9:08am
Oh that would give me so much hope!! I'm 43....and also had a TR done in late 2000....three years of trying (naturally except for 2 cycles of clomid)....
What are the results?????
What are the results?????
Patricia B.
|Mon, 09-15-2003 - 3:30am
Hello! Best wishes and good luck, dmd1002, canookie 7 and everyone.
Can you tell me what a TR is? I'm nearly 46, but haven't had an HSG. I miscarried several years ago (with a slight infection afterwards). Having conceived previously, and now FSH at 14 - 21 the clinic doesn't think its worth doing any investigations. I wonder tho' - my sister has endometriosis and I've heard this can run in families and can affect tubes. Thank you - Clunas.


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Jacob, Issac, and George Hosler came to Hocking County Abt 1820.Their father was Johanas Hassler from Pa. Jacob was born in Lebanon CO. Pa. At sometime the family moved to Ohio. May have been Hocking co. or may have been elsewhere.Would like to exchange information with Hosler Decendents.
Thank You
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Make way for The Real Housewives of Miami
The rumors were true and now it's official: Bravo's The Real Housewives of Miami, is hitting the airwaves Feb. 22, the network announced Thursday. And no, contrary to what you've heard, drag-que...
The rumors were true and now it's official: Bravo's The Real Housewives of Miami, is hitting the airwaves Feb. 22, the network announced Thursday. And no, contrary to what you've heard, drag-queen extraordinaire Elaine Lancaster didn't make the cut. She will make some drama-filled cameos, though.
Lea Black: Philanthropy and charity functions are her bag, so expect lots of dressing up. She and her husband, famed criminal defense attorney Roy Black, have a 9-year-old son.
Alexia Echevarria: The executive editor of Venue magazine lives on Miami Beach with her husband Herman. ``The Cuban Barbie'' has two sons from a previous marriage.
Marysol Patton: The PR diva owns the Patton Group, throwing hot parties, mostly revolving around fashion. Word is she gets romantically entangled while cameras roll.
Cristy Rice: A so-called basketball wife, the mom of five/Miami native recently divorced NBA star Glen Rice (they had some nasty scuffles). The show will follow her home and work life at her online children's clothing store, Bri Bri Boutique.
Adriana Sidi: The gallery owner of Adriana de Moura in Coral Gables also hits the social circuit pretty hard. The Brazilian bombshell is ``coming off a traumatic divorce,'' says the release, but the mother of one son is engaged to someone new.
Larsa Pippen: The former model is married to retired NBA star Scottie Pippen and they live in Fort Lauderdale. Bravo has this to say about the Lebanese beauty: ``When she's not busy turning her three little boys into star athletes, shopping for her one-year-old princess, or firing nannies, Larsa is happy to spend a little time on herself.''
Let the fur fly, ladies!
On Our Radar
On Our Radar
- One Direction loves Florida, records concert special
- Celebrity spotting in Miami
- What did most Miamians search for in 2014?
- See Fort Lauderdale native Jason Kennedy tie the knot
- Fleetwood Mac drummer Mick Fleetwood showcases his photography
- Ne-Yo plays Santa Claus in Kendall
- Rosario Dawson in Miami to talk new movie
- Diner en Blanc lands on Miami Beach
- Annie stars in Miami
- Shakira's mansion reportedly back on the market


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About this Conference:
Although pharma R&D and technology spending continues to increase, overall productivity is decreasing. To address this productivity gap, pharma and biotech must effectively manage and integrate data from all stages of the pharmaceutical value chain to enable more informed decisions. This is seen in the emerging trend of dedicated data science groups in pharma and the growing numbers of data scientists.
CHI's Seventh Annual Integrated Pharma Informatics & Data Science conference explores the transformation of current IT and informatics teams into data science groups and current progress made by such groups in the analysis, integration and visualization of complex data sets, including genomic, imaging, clinical, external/collaboration, and real world data. Dedicated sessions at the conference will focus on visualization and analysis of big data, and informatics in support of collaboration and externalization.
Day 1 | Day 2 | Day 3 | Plenary Session | Download Brochure
Monday, February 16
10:30 am Conference Program Registration
INTEGRATIon, ANALYsis AND VISUALIZATION OF PHARMA R&D DATA
11:50 Chairperson's Opening Remarks
Michael H. Elliott, CEO, Atrium Research & Consulting LLC
12:00 pm Using Informatics to Enable Precision Medicine in Oncology
Susie Stephens, Senior Director, Oncology & West Coast IT, Pfizer
Successfully enabling precision medicine for oncology requires a robust strategy for working with data, implementing analysis pipelines, and sharing results of analyses with scientists. This presentation highlights capabilities that have been enabled in these areas through a close collaboration between Oncology Research and Research IT.
12:30 Pharmacophore Informatics - Integrate, Analyze, and Visualize Pharma Research Data
Andreas Friese, Head, Research-IT, Bayer HealthCare R&D-IT, Bayer HealthCare AG
Pharmacophore Informatics (PIx) is an IT solution for Bayer HealthCare's Research Organization. The system uses "the power of data" to help the scientists to find the best drug candidates. Pharma research data is integrated, analyzed, and visualized - all in one system for easy usage by the scientist.
1:00 Session Break
1:15 Luncheon Presentation l: Bioinformatic and Information Solutions to Unlock the Power of Omics Data in Precision Medicine
Colin Williams, Director, Product Strategy, Intellectual Property & Science, Thomson Reuters
As volumes of Omics data and the number of applications in research and clinical care rapidly grows, organisations are faced with the problem of extracting relevant insights from that data to understand disease, identify drug targets and interpret patient genomic profiles. This presentation will talk about Thomson Reuters solutions to manage omics data and extract the relevant insights from this complex data through manual curation of information and sophisticated bioinformatics.
1:45 Luncheon Presentation II
Speaker to be Announced
2:15 Session Break
2:30 Chairperson's Remarks
Arturo J. Morales, Ph.D., Vice President, Informatics, Beryllium Corp.
2:40 Creating Public & Private Collaborations & Partnerships with Academic, Governmental and Industrial Partners around the Globe to Enable New Innovations to Take Patient Care "Beyond the Pill"
Robert J. Boland, Senior Manager, External Innovation R&D IT, Janssen, Pharmaceutical Companies of Johnson & Johnson
An overview of how translational research can improve the overall results within R&D and the technology architecture provides a new method for working collaboratively across partners. I will discuss how collaborative research can be obtained and remain secure to meet all regulations and show a visual of what a translational research environment would look like and examples of the types of research that can be developed in this type of environment.
3:10 Enabling Discovery Research through Partnerships, Collaboration Tools and Shared Transparency
In the age of externalization and research collaborations, informatics systems play a crucial role and must evolve. Although the exchange of files through portals and email keeps the process going, we must improve the transparency and data flow between systems to lower the physical barriers that we put in place.
3:40 Examining the Landscape of Solutions for Virtualized Research Ecosystems
Spending on Virtualized Research Ecosystems is growing over 20%, creating new data integration and information management challenges. Until recently, point solutions such as provisioning an internal system were the norm. However, this is inadequate for a multi-partner ecosystem. This talk examines trends, tools, and the impact of the cloud.
4:10 Sponsored Presentation
4:40 Break and Transition to Plenary Session
5:00 Plenary Session
6:00 Grand Opening Reception in the Exhibit Hall with Poster Viewing
7:30 Close of Day
Tuesday, February 17
7:00 am Registration and Morning Coffee
8:00 Plenary Session
9:00 Refreshment Break in the Exhibit Hall with Poster Viewing
10:05 Chairperson's Remarks
Martin Leach, Ph.D., Vice President, R&D IT, Biogen Idec
10:15 Experience & Challenges of Creating and Implementing a Data Science Function
Juergen Hammer, Ph.D., MBA, Roche Pharmaceutical Research and Early Development; Center Head, Informatics/IT; Global Head, Data Science, Roche Innovation Center New York
The Data Scientist profession has been named "The Sexiest Job of the 21st Century" and is often considered an essential component of Big Data Analytics. However, the Data Scientist Function in Pharma and Biotech is far from being established. I will discuss the organizational positioning of our multi-capability Data Science teams, how we measure performance, and which cultural shifts are required to maximize the impact of Data Science on the drug pipeline. I will provide a number of Data Science examples highlighting the importance of this Function in bridging the gap between massive content and end-user decision making in a world of deficient Application Landscapes.
10:45 Data Sciences at Biogen Idec
Biogen Idec established an enterprise-wide Data Sciences capability in July of 2013 to enable innovative data-driven approaches at the intersection of science, medicine and economics. We will discuss lessons learned in organizational structure and governance towards this goal. We will also describe our efforts to build out an inventory of inter-related cross-domain data assets across the Company to permit data exploration and analysis.
11:15 Hiring and Growing a Data Science Team – A Broader Industry Perspective
Jake Klamka, Founder, Insight Data Science Fellows Program
As the amount of data filling their servers has grown exponentially, Silicon Valley technology companies have aggressively scaled up their data science teams to extract value from this data. Data Scientists have a very unique skill set that is often hard to identify and hire for. The Insight Data Science Fellows Program has helped over 150 quantitative Ph.D.s transition to careers in data science at top companies like Facebook, LinkedIn, Twitter, Square, and many others. This talk will share lessons learned in selecting, hiring and growing a data science team based experience developing an elite data science fellowship program.
11:45 PANEL DISCUSSION: Assembly, Creation and Implementation of Data Science Groups for Pharma
Moderator: Martin Leach, Ph.D., Vice President, R&D IT, Biogen Idec
Panelists: Susie Stephens, Senior Director, Oncology & West Coast IT, Pfizer
12:15 pm Session Break
12:25 Luncheon Presentation l: Text Mining to Support Cancer Immunology Research
Maria Shkrob, Ph.D., Senior Bioinformatics Scientist, Biology Products Research, ELSEVIER
Recent progress in understanding the cellular and molecular mechanisms of cancer immunity has opened a new era in treatment strategies, including approaches that unleash the patient's own immune system to attack the tumor. To help scientists benefit from previously published research and keep up with the pace of this fast-growing field, we developed a text mining pipeline to aggregate information about immune cell biology. Using this pipeline, we created a knowledgebase that enables researchers to explore the complexity of molecular interactions underlying cancer immunity.
12:55 Luncheon Presentation ll (Sponsorship Opportunity Available)
1:25 Refreshment Break in the Exhibit Hall with Poster Viewing
2:00 Chairperson's Remarks
Barry Bunin, Ph.D., CEO, Collaborative Drug Discovery (CDD), Inc.
2:10 Enabling Secure Real World Data Exchange and Collaborative Analytics across Healthcare Organizations
Patrick Loerch, Director, Health IT, Information Technology, Merck & Co.
Healthcare reform, the decline in the price of genome sequencing and growing pressures from government and payers to demonstrate the effectiveness of novel therapies are creating a new market centered on access to real world data. The increasing economic pressures of this rapidly growing market are colliding with the need to ensure the security of patient data. We have developed, proven out and executed on a novel approach to enabling the secure sharing and collaborative analysis of real world data across healthcare organizations. As a representative of one of the core consumer bases of the secondary use of real world data we are introducing new modality for secure information exchange and collaborative analytics that benefits and meets the security needs of diverse healthcare organizations.
2:40 Modern Drug Research Informatics Applications to CNS, Infectious, Neglected, Rare, and Commercial Disease
Layering unique collaborative capabilities upon requisite drug discovery database functionality unlocks and amplifies synergy between biologists and chemists. The application of collaborative technologies to interrogate potency, selectively, and therapeutic windows of small molecule structure activity relationship data will be presented in half a dozen case studies. Novel collaborative technologies in the CDD Vault platform provide an ever-increasing competitive advantage for forward-leaning, open-minded collaborators.
3:10 The New FDA Janus Clinical Trial Repository: Data Harmonization Architecture for Accelerated Regulatory Review
Kelly McVearry, Ph.D., Chief Scientist, Ekagra Technologies in collaboration with FDA
FDA Janus Clinical Trials Repository (CTR) system, a standards-based clinical data repository for all future regulatory submissions and FDA medical reviewer analysis, is based on the Biomedical Research Integrated Domain Group model (BRIDG) and is designed to support industry standards and international initiatives for data interoperability, including inter alia Clinical Data Interchange Standards Consortium (CDISC); Health Level 7 (HL7); International Council on Harmonization adverse event classification system, the Medical Dictionary of Regulated Activity (MedDRA); the International Health Terminology Standards Development Organization (IHTSDO) Clinical Terms (SNO-MED CT), and the International Disease Classification System (ICD). The CTR system promotes interoperability through shared semantics and includes components for frictionless receipt, validation, loading, and management of submitted Study Data Tabulation Model (CDISC SDTM) data, CT standard selected by the FDA. Findings: FDA medical reviewers on the Janus CTR platform evaluation team were able to access harmonized datasets from multiple sources in a common platform with shared semantics, reporting decreased time-to-analysis (n=from 9 months to four hours for one therapeutic area) and improved data quality. Additionally, medical reviewers report the platform's ability to enable rapid meta-analysis, with seamless access to across-study datasets for the first time in FDA history.
3:40 ScienceCloud: Collaborative Workflows in Biologics Research and Development
Ton van Daelen, Ph.D.,
ScienceCloud Product Director, BIOVIA
Matt Hahn, Ph.D., CTO, BIOVIA
The life sciences industry has undergone dramatic changes and effective global collaboration has become a key success factor in this new age. BIOVIA is providing a hosted and comprehensive solution stack for externalized, collaborative research for pharma/biotech and CROs to address these new challenges. Recently we added support for biologics data management and IP capture. In this talk we will present collaborative and comprehensive capabilities in antibody characterization and development.
3:55 Sponsored Presentation (Opportunity Available)
4:10 Mardi Gras Celebration in the Exhibit Hall with Poster Viewing
5:00 Breakout Discussions in the Exhibit Hall
This interactive session provides attendees an opportunity to choose a specific discussion group to join. Each group has a moderator to ensure focused discussions around key issues within the topic. This format allows participants to meet potential collaborators, share examples from their work, vet ideas with peers, and be part of a group problem-solving endeavor. The discussions provide an informal exchange of ideas and are not meant to be a corporate or specific product discussion.
Informatics in Support of Collaboration and Externalization
Genomic Data-Sharing in a Proprietary World
Robert M. Kuhn, Ph.D., Associate Director, Genome Browser, Center for Biomolecular Science & Engineering, University of California Santa Cruz
Real World Data
Sebastien Lefebvre, Director R&D IT Platform, Biogen Idec
6:00 Close of Day
Wednesday, February 18
7:00 am Breakfast Presentation (Sponsorship Opportunity Available) or Morning Coffee
8:00 Plenary Session PANEL
9:45 Refreshment Break and Poster Competition Winner Announced in the Exhibit Hall
10:35 Chairperson's Remarks
Mark Schreiber, Ph.D., Director, Information Architecture, Merck Research Laboratories
10:45 Creating a Truly Innovative Holistic System that Captures and Channels Insights out to the Right People
Sebastien Lefebvre, Director, R&D IT Platform, Biogen Idec
Combination of technologies to harness data, with 21st Century social media concepts to channel the information to the right people. Gain insight into the recent launches of master data management, an information sharing portal and next generation search techniques.
11:15 Combining Machine & Human Intelligence to Successfully Integrate Biomedical Data
The biggest data challenge in the biomedical space is data variety. It is one of the three V's of Big Data—the others being volume and velocity. Much of this diverse data is highly valuable, but it is hard to integrate and interpret, as there is tremendous difference in terms of how things are described and recorded. The resulting variety not only increases the need for integration, it makes the effort much more challenging. In biomedicine, there is general awareness that modern research requires much better integration of information from as many sources as possible. And, since research is getting increasingly expensive, it is no longer seen as acceptable for the data resulting from experiments to be used by only one research project. Manual curation can produce high¬ quality results, but it can be difficult to scale and tends to be extremely expensive. To address this, Novartis began evaluating machine¬ learning approaches. That type of automated curation is very scalable, but it frequently does not deliver the kind of precision that data scientists expect. Data variety is, in part, a human problem. Unlike volume and velocity, you cannot just throw technology at it. There is a very important and necessary human role to play, even in a highly automated solution. In an attempt to merge the machine learning and human expertise approaches we have partnered with academia and industry to develop a hybrid machine-learning and crowd-sourcing approach to data integration problems. The results of these approaches, both social and technical, will be discussed.
11:45 A Global Approach to Genomic Data Using the UCSC Genome Browser
A large number of datasets exist to assist in the interpretation of genomic data. Variants are being accumulated in many different databases, and many, often competing, efforts have been made to aggregate the data in super databases, but sharing between them is limited. The UCSC GenomeBrowser is a public resource that operates under a clearinghouse paradigm, pulling in as many useful databases as possible and allowing a researcher to visualize data from any or all of them at once, along with private data, in a consistent display framework.
12:25 Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own
1:00 Refreshment Break in the Exhibit Hall and Last Chance for Poster Viewing
1:40 Chairperson's Remarks
Ajay Shah, Ph.D., MBA, PMP, Director, Research Informatics & Systems, City of Hope National Medical Center
1:50 Finding Cohorts for Clinical Trials – An Integrated Informatics Approach
Integrating discovery, clinical and translational research informatics systems and data can help solve one of the key challenges in clinical trials – finding cohorts for clinical trials. SPIRIT – Software Platform for Integrated Research Information and Transformation is utilized to encode computable eligibility criteria, identify cohorts from EMR system via i2b2 and perform cohort analytics and visualization.
2:20 Building the High Performance Genomics Big Data Platform to Support Drug Discovery &Translational Medicine
Monica Wang, Ph.D., Lead Software Engineer, Project and Program Manager, Research Systems, Takeda
With the great advance of sequencing technology, vast amounts of genomics data is being generated every day. The ultimate challenge will be to best utilize the data and extract knowledge out of it to advance science and medicine. We will share our experience building the enterprise Genomics Big Data Platform with a focus on high performance to support our internal research effort for drug discovery and translational medicine.
2:50 Hackathons: Feed Innovation, Creativity, and Promote Thinking Outside of the Box
Kristen Cleveland, PMP, Senior IT Project Manager, R&D IT, Biogen Idec
Explore what a Hackathon is, how to plan it, and how to get the best out of the event for your organization.
3:20 LiveDesign - Schrödinger's Next Generation Platform for Collaborative Drug Design
Mark Brewer, Research Leader, Drug Discovery Applications Group, Schrödinger
Medicinal chemists can benefit enormously when collaborating with their computational team members but, in practice, the collaborative process can be challenging and time-consuming. LiveDesign addresses these challenges head-on by providing a platform for enabling real-time collaboration and design by all members of a drug discovery team. In this presentation, we discuss the LiveDesign platform and how it is integrated into existing pharma workflows and infrastructure in order to accelerate small-molecule design processes.
3:50 Refreshment Break
4:00 Chairperson's Remarks
4:10 KEYNOTE PRESENTATION: Global Exchange of Human Genetic Data for Medicine and Research
David Haussler, Ph.D., Distinguished Professor and Scientific Director, UC Santa Cruz Genomics Institute, University of California Santa Cruz
Every human disease is a rare disease at the molecular level. No single institute has enough patients to understand any particular molecular subtype. For genomics to benefit medicine and science, we must share data. This presentation outlines the data standards and Application Programming Interfaces developed by the Global Alliance for Genomics and Health that are intended to address this issue, and highlight a few global genomics projects that use them.
4:40 SIDRAiTrip Data Mining Framework in Building Personalized Medicine Based on the Integrated Phenotypic and Omics Databases
Emad Elsebakhi, Ph.D., Principal Investigator, Division of Biomedical Informatics, Sidra Medical and Research Center
Rashid Al Ali, Ph.D., Deputy Chief Research Officer and Division Chief Biomedical Informatics, Sidra Medical and Research Center
Over the next 10 years in the Genomic Wide Association Study (GWAS), it is anticipated that the employment of novel predictive modeling techniques will be significantly increased in both analytics and knowledge management which will lead to complex decision support tools. These innovative tools will enable researchers and physician to achieve their main goal of GAW to evaluate the existing analytical and modeling methods and to provide an impetus for developing new methods.
5:10 XPRIZE: Transforming Science Fiction into Science Reality through Incentivized Competition
Grant Campany, Senior Director, XPRIZE
Imagine a portable, wireless device in the palm of your hand that monitors and diagnoses your health conditions. That's the technology envisioned by the $10 million Qualcomm Tricorder XPRIZE competition, and it will allow unprecedented access to personal health metrics. The end result: Radical innovation in healthcare that will give individuals far greater choices in when, where, and how they receive care.
5:40 Close of Conference Program
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text:
Winnipeg Free Press - PRINT EDITION
Grit, gimmicks stifle Jets, fans
Wild employ strong defence, anthem trickery in victory
ST. PAUL, MINN. -- First, they stifled the Winnipeg Jets fans.
And then they stifled the Winnipeg Jets.
The Minnesota Wild put on a smothering exhibition of hockey against the Jets at Xcel Energy Center Sunday night, devising a gimmick to take visiting Jets fans out of the game and then doing the same for their team with good, old-fashioned defensive play.
By night's end, the latter plan worked better than the former -- there was no shutting up the thousands of Jets fans who made this trip south, although the Wild tried, with a French version of the Canadian anthem to start the night that was clearly aimed at trying to prevent the visitors from shouting out their presence in the arena with a trademark shout of "True North."
But on the ice, the Wild executed a scheme to silence the Jets players to near perfection, holding Winnipeg to just two shots in the first period and then earning a hard-fought 2-1 victory with a late third-period goal.
The loss snapped a four-game winning streak for Winnipeg and dropped them back to .500 for the season at 10-10-2.
After the game, Jets players were left to wonder what might have been after the second consecutive 2-1 loss to the Wild this season.
"Tonight's a game we could have won," said centre Bryan Little. "We had a pretty slow start in the first period, but we were a few minutes away from forcing another overtime. And we've been pretty hot there."
The Jets had three straight shootout wins coming into Sunday night.
A Dustin Byfuglien deflection of a Little shot just 54 seconds into the third period tied the game 1-1, but the Jets could not close the deal and yielded the game-winner at 16:48 of the third when Minnesota's Mikko Koivu scored his second of the game.
Central Troubles
The loss dropped Winnipeg's record against Central Division opponents to just 3-8-1, something that's going to have to improve dramatically if Winnipeg intends to be in the playoff conversation come season's end.
But Jets forward Blake Wheeler thinks his team's record against division rivals thus far is misleading.
"I like the way we play against these teams. I argue we have the toughest division in hockey and I haven't been a part of a game yet where I felt outmatched," said Wheeler.
"I feel like we're every bit as good as even the best teams in our league."
Buff on a roll
With another goal Sunday, Jets defenceman Dustin Byfuglien has now scored three goals in his last two games and four goals in his last four games.
Add to that a goal against the Nashville Predators he had taken away and it would seem he has safely excised that goal-scoring monkey from his back this month.
Little, who took the third-period shot that Byfuglien was credited with deflecting into the Wild net, was asked if he thought Byfuglien actually touched the puck.
Little laughed.
"He probably says he did," Little grinned. "If he wants it that bad, he can take it."
Ellerby Steps In
With Zach Bogosian week-to-week with a groin injury, waiver pickup Keaton Ellerby stepped up Sunday night to take Bogosian's customary spot next to regular defensive partner Toby Enstrom.
Ellerby finished the night minus-2, but was serviceable in playing just over 22 minutes, said his head coach.
"I thought Ellerby was real good. I thought he played smart," said Noel. "He moved the puck. It didn't look like the extra minutes was an issue. I thought he was smart, managed it well."
Up Next
While they lost on the road Sunday night, they have another winning streak they will take into their game tonight at the MTS Centre against the Calgary Flames -- a four-game home winning streak.
After having started the last five games in a row for Winnipeg, it's widely expected Noel will give goaltender Ondrej Pavelec the night off against the Flames in favour of backup Al Montoya.
Republished from the Winnipeg Free Press print edition November 18, 2013 C3
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34 year old woman | Conshohocken, PA, USA | Seeking men 27-37 within 40 miles
Active within 24 hours
So, a little about me... Friends and family are most important - my 2 year old niece is my biggest love. I like to explore and travel. Always open to trying new things and having new experiences. I consider myself a very loyal person and it's something I value a lot in other people. Love going to concerts - probably been to about 70 shows over the years. I am infamous for my napping skills and I'm not ashamed to admit it :) At the same time, I like staying active - spinning and yoga are my favorite. I am an avid Jeopardy and HGTV watcher (yes, I am a dork) and will try any kind of food at least once...I have a very adventurous palette! I'm looking for someone to challenge me and make me laugh. I especially appreciate goofy humor. I like an open minded and family oriented person. Someone who doesn't take themselves too seriously and tries to get the most out of life.
Alumni connections , Coffee and conversation , Cooking , Dining out , Hobbies and crafts , Movies/Videos , Museums and art , Music and concerts , Exploring new areas , Nightclubs/Dancing , Performing arts , Playing cards , Playing sports , Shopping/Antiques , Travel/Sightseeing , Volunteering , Watching sports , Wine tasting
Aerobics, Cycling, Dancing, Other types of exercise, Running, Soccer, Swimming, Walking / Hiking, Weights / Machines, Yoga
I exercise 3-4 times per week.
I have Dogs
Dogs are the best, in my opinion.
Middle of the Road
I'm a Jersey girl at heart, so the beach is one of my favorite places. I like hanging out in Conshy and occasionally venture into Philly to try new bars or restaurants.
Saint Joseph's University, Philadelphia, PA
Love all kinds of music and going to concerts, especially in the summer time. Favorite live band is DMB, but I've seen a variety of artists from country to jazz, pop to rap.
I love being with my friends. Exploring new things. I am social person and love being around people. Love live music. Going to the movies. Reading. Eating good food. Traveling to a new place at every opportunity.
Game of Thrones, the 3rd book; The Great Gatsby; The Fault in Our Stars
Z{{Cta}} {{#if HasMoreInfo}} ?{{CtaSecondary}} {{/if}}
|What she is looking for
|5'1" (154cms)
|5'5" (165cms) to 6'5" (195cms)
|Body type:
|About average
|About average, Athletic and toned
|No preference
|Dark blonde
|No preference
|No Way
|No Way
|Social Drinker
|Social Drinker
|I'll tell you later
|No preference
|I'll tell you later
|No preference
|Never Married
|No preference
|Have kids:
|Wants kids:
|Background / Values
|White / Caucasian
|White / Caucasian
Italian, with a little British
|Christian / Catholic
|No preference
|Graduate degree
|No preference
Studied Higher Education at Drexel Univ for my Masters.


text:
Filed under: Stress
Progressive muscle relaxation (PMR) is a way to relieve the physical symptoms of stress and anxiety that show up as tense, aching muscles. This mind-body practice helps you consciously release muscle tension so that you're able to function throughout the day and relax during downtime. Using PMR, you learn to release tension and develop deep relaxation by actively tensing and then relaxing the muscles throughout your body. The outcome: You can train your body to relax on command. Check out the description of how to do PMR in the Controlled Response handbook section of the OSOK Total Force Fitness program.
For more information on relaxation strategies, check out the Stress Control resources in HPRC's Mind Tactics domain.
Researchers have long been interested in meditation and its potential benefits. A recent study found that regular meditation practice of 20 minutes a day has a lasting effect on how your brain processes emotions. This suggests that meditation could potentially help your brain handle stress, anxiety, and depression, and possibly other feelings. For those individuals dealing with relocation, deployment after-effects, chronic stress overload, recent family changes, or new training assignments, having a strategy to improve your resilience and help process the expected extra doses of emotions can be helpful.
For more information on meditation, visit the National Center for Complementary and Alternative Medicine's meditation page. HPRC will be adding a new section on Mind-Body Strategies in the near future that will give you more resources, too—so check back for that.
Many jobs involve duties that can cause minor musculoskeletal tension that builds over time until you find yourself experiencing pain. Sitting or standing for long periods of time, lifting or carrying heavy objects, and other common mission-related actions of active-duty personnel wear on the body, leading to increased risk for injury. Yoga can help to reduce this risk by improving posture, increasing energy, and stretching overused or tense muscles. If you don't have time for yoga between work, your normal exercise routine, or family obligations, suggest sharing a quick yoga session with buddies in your unit during a break to reduce your risk for injury and help get through the afternoon. There are different styles of yoga for all skill levels.
Virtual reality was first introduced as a therapy tool for people with anxiety disorders such as phobias, but it is now used for a wide range of conditions, from PTSD to childhood ADHD. In fact, it recently warranted its own symposium at Walter Reed National Military Medical Center, where experts exchanged ideas on the current state of research.
Virtual environments used in therapy sessions are created for the individual's needs—for example, a noisy classroom for a child with ADHD, the re-creation of the 9/11 attacks for a firefighter or police officer, or "Virtual Iraq" for a soldier. "Virtual Afghanistan" is the newest creation and is already being used to help service members overcome PTSD. Active-duty men and women are gradually brought back to their traumatic event using the virtual world as the therapist provides verbal cues to facilitate the healing process.
With a view to mitigating future need for therapy, a series of episodes is currently being created to provide pre-deployment "Stress Resilience Training for Warfighters." The goal is to help reduce the risk of PTSD and better prepare warriors for actual scenarios they will encounter in theater.
For more information about how to prevent and manage stress, visit HPRC's Stress Control section.
When you're in pain, any relief is welcome. The good news is that researchers have found pain can be managed and alleviated, to a degree, by employing strategies that have you put your focus elsewhere. Meditation is one such strategy. A recent small study examined the experience of pain from fourteen experienced meditators and fourteen inexperienced participants. It turns out that the old adage is true: Practice makes perfect. The experienced meditators experienced pain to a lesser degree and got used to the pain more quickly. They also registered less anxiety than the unpracticed participants. The message? Practicing meditation regularly may improve how your brain handles pain.
For more information see the write-up on the University of Wisconsin's news page or the research article.
And tune in again later for HPRC's new section in Total Force Fitness on pain management—coming soon.
With the holidays upon us, the number of problems that you have to solve might be kicking up a notch or two. A Department of Defense and Veterans Affairs initiative, Moving Forward, has a website that gives you tools for "overcoming life's challenges." As you encounter challenges this holiday season, give their module a test run—it takes you through a step-by-step process for solving problems. They suggest:
- Define the problem and set goals
- Come up with alternative solutions.
- Pick one solution
- Put your solution into action and analyze the outcome.
HPRC's website also has useful information on stress management.
It's how you react to stressful situations—not the causes of stress themselves—that can affect your future health. Research has shown that people who react more strongly and remain "stressed out" longer are more likely to develop chronic diseases such as heart conditions and arthritis.
Even if you can't control the stressful situations you find yourself in, you can learn to control how you react to them. Simple mind-body strategies such as deep breathing and cognitive reframing can help. Try some of the relaxation strategies from the Navy & Marine Public Health Center website the next time you find yourself reacting to a stressful situation and see if they make a difference.
Understanding how stress affects you both mentally and physically in high-stress situations is important for optimal performance—which is why training under stress is a central part of combat preparation. Knowing what your reactions are, when to pause and take a deep breath, how to use positive self-talk, when to recalibrate one's physical responses, and how to recharge (sleep and proper nutrition) after a stressful event are key for being at your peak mental performance. Getting support from comrades and using appropriate humor also can help relieve stress.
The holidays can sometimes be a stressful time filled with loved ones and activities. This year, try practicing one of the healthy stress busters you can find on HPRC's website—by yourself or with your family. For example, give brief meditation a try.
You can even try this as a family: Have someone lead the meditation and give occasional cues. Note that this generally works better with older children!
For more information on strategies for stress, visit the Stress Control section in HPRC's Mind Tactics domain.
Not being able to quiet your mind at night can be very frustrating— and it's not just an "adult" problem. If your child has difficulty sleeping because of a restless mind, try setting aside some "worry time" during the day. Help your child create a "worry box" and personalize it through art. Children can write down their worries—each on a separate index card—and deposit the worry in the worry box. Doing this while getting ready for bedtime can be a good way to spend some quality time with your child every night. For more information on sleep strategies, visit HPRC's Mind Tactics section.


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Subic Get AwayThis photo was shot on film. Taken by renenob with a Vivitar Ultra Wide & Slim loaded with Photo Porst Chrome X 100 film in Subic, Olongapo, Philippines. These tags describe this photo: lomography, summer, rene, nob, analog, and beach. Date: 2008-04. Time: Morning. This photo can also be found in the album Subic, Philippines.
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Design Toscano KY71004 Fiona the Flower Fairy Sculpture
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At nearly a foot-and-a-half tall, Fiona lends a magical presence with her lacy butterfly wings, flower-wreathed curls and delicate fingertips. This exquisite sculpt is from the workshop of artist Evelyn Myers Hartley and cast in quality designer resin. Fiona is finished in faux antique stone as the perfect accent, whether peeking from a flowerbed or resting on your bedroom floor.
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Gene Rice is a HUD Section 8/202 apartment community designed especially for the elderly and mobility impaired living. You'll find everything you want and need here -- including utilities -- at an affordable, subsidized price.
Our property is located near Valley METRO bus stop, Banner Dell E. Webb Medical Center, Arrowhead Mall, and other shopping and dining services. The beautiful grounds of the apartment feature a park like atmosphere. Rental units include the following great amenities emergency call systems. This 84-unit Tiempo community offers studio and one-bedroom apartments in a park-like atmosphere with in-unit emergency call systems, a large recreational room with up-to-date library, gazebo with barbecue grill, and well-landscaped, spacious grounds. With so many options for fun, you'll only need to leave the grounds for shopping or errands, and both are a snap to get to from Gene Rice. The property is conveniently located in the sun-soaked city of Peoria, a large suburb of Phoenix. And with the Valley METRO bus stop right outside the front door, residents are mere minutes from several nearby medical facilities including Banner Dell E. Webb Medical Center. In addition, Arrowhead Mall and other shopping, services, and restaurants are all minutes from this community.
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text: Roraima Trek Roraima is one of the best trekking trips in Latin America. Trek to the lost world to receive incredible views and meet another world with 70% of endemic lifestyle. This is unique in the world. Day 1: In the morning we leave Santa Elena for a 2 hours drive to the last Indian Village before Roraima. Paraitepuy is 1600 m above sea level and will be our starting point for the trekking to the Lost World. We will walk about 5 hours trough open savannah before reaching the Tök Camp at a height of 1050m. Day 2: After a good breakfast we start a five-hour walk to the base camp, which is 1870m above sea level. In order to reach it we need to cross two rivers, which can be tricky because the Kukenan River grows after rainfall to a respectful stream. Our experienced guides will help with the first adventure crossing the river. The walk also requires 2 hours uphill walking. On our way we will cross smooth hills in the savannah and beautiful landscapes covered with orchids and carnivores. Here starts the jungle so we should use the late afternoon light to find some attractive shots for our cameras. Day 3: After having breakfast in the camp we start off to the tough part of the day: a 2-hour steep hike in the jungle. Afterwards we will be exhausted but amazed by the beauty and the overwhelming number of bromeliads, ferns and other rare plants. Finally we can touch the wall of the Roraima Mountain and a small waterfall will bring us our much needed refreshment! From there we need another hour to ninety minutes to reach the top, which is 2700 meters above sea level. The path leads us through the jungle and over stones of different forms and shapes. Stones looking like sea turtles or dragonheads welcome you finally at the top. Now we have the whole afternoon for discovering the closer area around the camp. Day 4: The whole day we will discover the mystical top of the Roraima and feel the magic related to the mountain. We will find thousands of faces and sculptures in bizarre stone formations, some might remind us of lizards or Fidel Castro, others will seem to us like fantasy creatures or fairy tale witches. We will be amazed by the valley of crystals and the fantastic view from the top of Roraima to the valley. When the fog rises up the mountain we can feel the mystery. And do not be surprised when you feel like you are walking on the moon because the surface looks just alike. Day 5: In the morning we will have a last chance to take some pictures before you descend the mountain again to reach the campsite at Rio Tök. Today we have to walk about 7 hours downhill that means from 2700m down to 1050m above sea level. Shortly before the camp we have to cross the two rivers from the first day again. A light lunch is given on the way and at the camp there will be served a warm meal. At the end of the day we can enjoy a great swim in the river with a fabulous view to the Kukenan and Roraima mountains. www.backpacker-tours.com -1- email@example.com Roraima Trek Day 6: After the last four hours of walking we will reach the Indian village Paraitepuy again. Please watch out! Every tourist is searched for crystals by the park rangers. The crystals are a lot more beautiful on the top of Roraima then in your apartment at home! Our Toyotas are already waiting for us with cold drinks and lunch. After lunch we go back to Santa Elena. In agreement of the group there is a short stop at the Quebrada de Jaspe with its brilliant red shining Jaspe stones. Roraima `s day phases: 1. Day: Paraitepui – Tök Camp 2. Day: Tök Camp – Base Camp 3. Day: Base Camp – Camp 4. Day: Hochplateau 5. Day: Camp – Tök Camp 6. Day: Tök Camp – Paraitepui This Tour includes: • Transfer forth and back from Santa Elena to Paraitepuy • Professional guide, bilingual • Tents, sleeping bags and ground mats • 5x breakfast, 6x lunch, 5 x dinner • A warm meal and cold drinks at your arrival in Paraitepuy the last day • Porters for tents, food and cooking gear • Transportable toilet • Communication on the way and first aid kit We recommend taking the following items with you: • Good walking shoes and sandals • Thick socks and 2 pairs of socks for the river crossing • Sun hat and sun cream • Bottle for water and insect repellent • Short or light pans for the hike • Good raincoat and flashlight • Some sweets • Passport We recommend not bringing more than 10kg with you! www.backpacker-tours.com -2- email@example.com


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Added Jan 17, 2013
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Jan 20, 2013, 11.01 PMby Mary Athey
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Lovely! Your coat looks really cool and the lining with the heart is sweet <3
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Thank you so much :)
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Yet it is still inspiring for cooks and chefs, giving fresh ideas of what is good and what makes sense.
Coco is a juried show of some of the finest young chefs, selected by some of the most innovative and storied chefs of our time.
The same could be said about the more traditional choices by chefs like Alice Waters and Fergus Henderson.
the visual layout of the book is slightly old-fashioned, pictures etc could be better but the content is good. Read morePublished 15 months ago by Kristof Stevens
great book, very good for chefs and profesional of gastronomy industry!, no doubt to buy it. Excelent for students and restaurantesPublished 19 months ago by Christian Jiménez Lira
this book has a lot of good names in it like ferran adria and gordan ramsay. the pictures and dishes are very impressive the only downfall is that the recipes dont do their dishes... Read morePublished 21 months ago by Thomas Baader
very good restaurant and, recipe book!
someday! i will eat all restaurant in this book!!!!!!!!!
this book is make me feel so beating!!!
This is a very unique cookbook. Showcasing 100 "up-and-coming" chefs, selected by 10 leading world chefs, each is a brief snippet of what the chef does and why they were chosen. Read morePublished on November 27, 2011 by Bradley Nelson


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Willamette Week's Stern takes county job
- Matt Kish
- Business Journal staff writer
Willamette Week managing news editor Hank Stern is leaving the weekly newspaper to take a communications job with Multnomah County.
He'll start his new job on April 20. His last day at Willamette Week will be April 19.
Stern has a strong reputation as a watchdog reporter. He joined Willamette Week in 2005 after working as a reporter at The Oregonian for seven years. In his time at Willamette Week, the newspaper regularly won top honors at the statewide journalism contest run by the Oregon chapter of the Society of Professional Journalists.
(Disclosure: I served on the board of Oregon's SPJ chapter with Stern.)
Stern will fill a job that opened up when Tara Bowen-Biggs left the county to take a job organizing an upcoming conference for NACo, a trade group for county governments.
His new salary is $80,000.
"It's better pay, benefits and I respect what the county's doing," Stern said. "It made a hard decision a little bit easier."
The Portland Mercury first reported the story.
Stern's new boss, David Austin, met Stern 13 years ago when they both worked at The Oregonian. At the time, Stern covered local government for the daily paper.
"He knows the issues we face on a daily basis," Austin said. "He brings a straight focus to our work, but he also brings a little bit of an edge because he worked for Willamette Week."
Stern will work with elected officials and agency heads in his new role.
"More and more people are turning to social services," Austin said. "To have someone of Hank's caliber helping us get the word out about the county's important programs, it's a total plus for us."
Willamette Week hasn't announced a plan to fill Stern's position.
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Godsey Martin is a fast growing, high energy, and fun loving personal injury law firm located in downtown Dallas. We seek visionaries and trendsetters who look to take their careers to the next level. Our managers encourage team members to "think outside the box" and be ...
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The Godsey Martin Law Firm is looking to add an Assistant Settlement Negotiator to its family. We are a fast growing, high volume firm that has a big heart for people. We would like to welcome an aggressive and hardworking individual to our team. The person must have a ...
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Because of our continual success we are growing by leaps and bounds, and we need an Assistant Case Manager ASAP!
The Godsey Martin Law Firm is a multi-million dollar personal injury law firm. Our mission is to get our clients justice and top compensation for their injuries. ...
Real Estate Attorney with 2-4 years of leasing and title experience
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The Godsey Martin Law Firm is looking to add a Settlement Negotiator to its family. We are a fast growing, high volume firm that has a big heart for people. We would like to welcome an aggressive and hardworking individual to our team. The person must have a passion for ...
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Database Administrator / Paralegal
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Janelle Monáe to Perform With FUN. at the Grammy Nominations Concert
Singer/songwriter Janelle Monáe will perform with FUN. on "The GRAMMY® Nominations Concert Live!! - Countdown To Music's Biggest Night®." Additionally, nine-time GRAMMY winner Sheryl Crow, country group Little Big Town, folk/rock group The Lumineers and country singer Chris Young have been added as presenters for the one-hour special. They join previously announced performers Luke Bryan, Hunter Hayes, three-time GRAMMY-winning group Maroon 5, three-time GRAMMY winner Ne-Yo, Recording Academy Lifetime Achievement Award recipients The Who, and The Band Perry and Dierks Bentley in a special tribute to Johnny Cash. Two-time GRAMMY winner LL Cool J and six-time GRAMMY winner Taylor Swift will co-host the one-hour concert special. The show - which will announce nominations in several categories as well as feature performances by past GRAMMY winners and/or nominees - will take place live for the first time ever at Bridgestone Arena in Nashville, Tenn., on Wednesday, Dec. 5, and will be broadcast in HDTV and 5.1 surround sound on the CBS Television Network (www.cbs.com) from 10 – 11 p.m. ET/PT (9 p.m. Central). For updates and breaking news, please visit www.grammy.com, and The Recording Academy®'s social networks on Twitter and Facebook: www.twitter.com/thegrammys, www.facebook.com/thegrammys.
Following the one-hour live telecast, guests will experience an exclusive one-hour concert by Maroon 5. Tickets for "The GRAMMY Nominations Concert Live!! - Countdown To Music's Biggest Night" are on sale now and are available online at www.ticketmaster.com or via Ticketmaster charge-by-phone lines at 800.745.3000.
For the second consecutive year, music fans can view live backstage coverage of the nominations by logging on to www.grammy.com/live or http://new.livestream.com/thegrammys/grammylive immediately following the live telecast (11 p.m. ET/8 p.m. PT).
About Author
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- Jason Aldean Among Winners of Inaugural AMERICAN COUNTRY COUNTDOWN AWARDS; Full List
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- The Recording Academy Launches 57th Annual GRAMMY AWARDS Ad Campaign
- Harry Connick Jr. Adds New York Date to 2015 Winter Tour
- VIDEO: Ashton Kutcher Talks TWO AND A HALF MEN Finale on Ellen


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Digital Design
The brief of this project was to create a cargo bike with an electrical assistance recharged by solar energy.
Let's look the project on Behance or my website to get the explications :
Software :
Autodesk Alias Studio
Autodesk 3ds Max / V-ray
Adobe After Effect
Adobe Audition
Gear used :
Canon 60D
Music : Cee-Roo - Work Song
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text:
General Info
I live in Athens, Greece
About myself
Marital Status
About my Partner
Looking for
Male, Gay-Couple, Group
Top Comments
All Comments
nice tits. my load would look so good all over them. too bad no vids.
Thanks for add to friends!
thanks, sexy
thanks for the friend request, hot nip stud!!
Thanks for the friend request
Thank you for adding me.
Thanks for the watch *hugs and gropes* I hope you enjoy and rate my vids if you like them ^^ love my nips too
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http://www.xtube.com the hairyness
thanks for the request
tnks for request
Thnx - Wanna Jack of together in the near future? ( add me on Skype: lars---dk )
Thanks for the friend request!
wraios, efxaristw man
you like your nipples done?
Thanks for the invite, friend. Woof!
Thanks for the add
thanks for the add bro
Ok. Added !
Ευχαριστω και εγω για την αποδοχη!!! Απλα τελειος...!!!!
Thanx for the invite, m8!
http://www.xtube.com for the invite!
Thanks for the friend request!
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I had decided to close my account. this was not me, because I work in the public service. this profile will be closed in a moment.
hey, I found your comment one one of my picture in the album "big, bigger, the biggest!" in kanell03's profil.
thank you.
Thanks for your request! You're incredibly sexy;-)
G'day handsome,
Thanks for the friend request.
Yeah! Great chest!
Hugs n tugs,
Queensland Australia
Thx for add
tks 4 add
Glad to have you as a FFriend!
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|nippletitlove Added a video to favorite
|nippletitlove Added a video to favorite