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- South America »
- Argentina »
- Buenos Aires »
- Bahía Blanca »
- Radio Universal
Tune in to Derrapando 1° Emision, Transnoshe Universal, as well as broadcasts like Otro Dia, in addition to others.
Bahía Blanca - Buenos Aires, Argentina - Spanish
Viva La Radio Corazon Latino De aqui a la movida Domingo Universal Frente A Cano See all shows...
Songs playing in Radio Universal
Get our Simple Radio app for iOS devices (download here).
Android app is coming soon, so stay tuned!
We've also developed a mobile website that will work on all devices. You can check it out by visiting our mobile radio site from your phone or tablet's mobile browser - it's free, no download required. For more information go to our Mobile Support Site .
In other languages
See this page in French: Ecouter Radio Universal en ligne
See this page in German: Hören Radio Universal online
See this page in Portuguese: Reproduzir Radio Universal ao vivo
See this page in Spanish: Escuchar Radio Universal en vivo


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Search Results for gun accessories approach
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Final Approach X-2 Hunting Blind
hunting blind you could ask for. Final approach hunting accessories are all about keeping you mobile ... Final Approach X2 Hunting Blinds are a complete combination package for excellent concealment ... and useful storage. The X-2 Shooting Blind from Final Approach can be utilized as a hunting backpack ... at bringing home a trophy with the X-2 Blind. Final Approach 432495: X-2 Realtree Max-5 Duck Blind ... Final Approach 432445: X-2 Mossy Oak Blades Duck Blind Specifications for FA Brand X2 Ground Blind: ... Dimensions: 26" W x 84" L x 14" H Weight: only 12 lbs. Features of Final Approach Blind X-2: ... in concealment Padded headrest and gun rest Original fast-access side flagging holes Double waterproof poly...
Starts at $163.49
Final Approach Sport Utility Blinds
you've come to expect from all FinalApproach Hunting Accessories - and it fits just about anywhere! Final ... Approach a premier provider of high quality hunting accessories. Hunting Accessories by Final ... retail customers. We sell FinalApproach Hunting Accessories for the best price online. Final ... Final Approach Sport Utility Eliminator SUB Blinds feature comfortable padded reclined seating ... and insulated foot bag for warmth. The newly-designed FA hunting accessory for the perfect fit! Now ... "Sport Utility Blind" by Final Approach incorporates the excellent quality and rugged durability ... Approach are field-tested and enjoy a reputation of quality and value amongst shooters, hunters and other...
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Starts at $173.49
Final Approach Pro Guide XL,42x90x20in
heavy clothing, this Hunting Accessory from Final Approach provides 15% more room to meet your ... needs. The padded head and gun rest in the Final Approach Pro Guide Extra Large Ground Blind keeps you ... Comfortable and spacious, the Final Approach Pro Guide XL, 42x90x20in offers a roomy interior ... pickups, the multi-purpose Final Approach Pro Guide Giant Blind is the most versatile blind available. ... Final Approach 432795: Pro Guide XL,42x90x20in,Realtree Max-5 Final Approach 432745: Pro Guide ... XL,42x90x20in,Mossy Oak Blades Specifications for Final Approach Pro Guide XL, 42x90x20in: Weight: 20 ... Features of Final Approach Pro Guide XL, 42x90x20in: 15% larger to accommodate hunters...
Starts at $268.99
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In a day when some preachers are compromising their moral standards or stretching the truth if it suits their purposes, Jack Hayford is still a paragon of strength, maturity and humility. read more
Charisma Magazine
Page 7 of 28
DOJ Diversity Police Seeking to Shackle Christians
How can we stop the current administration from trampling on our religious freedoms and enforcing a radical gay agenda that most Americans don't accept? read more
Government Forcing Employees to Affirm Homosexuality
Can you believe the Department of Justice is forcing federal employees to publicly affirm homosexuality? Silence is considered disapproval. read more
Help My Friend Help Unborn Babies
By supporting Ben Ferrell's run in the Rock 'n' Roll half-marathon in San Diego this weekend, you can take part in saving the lives of babies in Israel. read more
Our Interview With Paul and Jan Crouch
Take a journey into our archives to read our 1983 story about TBN and an interview with Paul and Jan Crouch. read more
Hungry for God's Power
Read why we must honor the Holy Spirit and do more than simply remember the day of Pentecost. read more
Tragedy Sparks the Church to Spring Into Action
The citizens of central Oklahoma have been through a terrible tragedy this week. Read about how quickly local and national churches are responding to help. read more
The Real Power Behind Pentecost
Charisma Publisher Steve Strang shares why we must do more than just remember the Day of Pentecost. read more
What Pentecost Means to Both Christians and Jews
Israel's Independence Day falls on Shavuot, also known as Pentecost, when Moses received the Law. Next Sunday, we Christians celebrate the founding of the church, when the Holy Spirit fell on the Day of Pentecost 10 days after Jesus ascended to heaven. read more
I'm Inspired By How God Is Using Business Leaders Worldwide
There's a greater reason for optimism than you may realize when it comes to business and the gospel read more
Bible Scholar: The NEW Date for Christ's Return
Why one Bible scholar is arguing that Hal Lindsey's famous 1988 prediction for Christ's ...
Get R.T. Kendall's New Book & Devotional
Experience the Holy Spirit in a way that will change your life!
Prophetic Dream: You Will Learn to Fly
Three groups of people featured in this startling end-times dream. In which group will you find ...
5 Ways to Position Yourself to Fulfill God's Call
I watched a single woman become ordained to go to the nations last Sunday. Here are 5 things she ...
When Christians Struggle With Mental Illness
The church has put a stigma on Christians fighting a mental illness. Yet the cause could be ...
Why I Don't Tell My Children About Santa
This mom shares why she doesn't include Santa in her Christmas celebration.
Why Are Some Pastors So Against Intercession?
There are many reasons why, but Scripture is clear about our call to pray.
"Warn My People to Avoid This Dangerous, Raging Cloud!"
This cloud has plagued the people of God for thousands of years, and it's rearing its insidious ...
10 Rites of Passage to Spiritual Influence and Authority
If you are praying for God to enlarge your territory, consider these 10 steps in Christ's ...
Get R.T. Kendall's New Book & Devotional
Experience the Holy Spirit in a way that will change your life!
How Christian Marriages Don't Enjoy One of God's Greatest Gifts
Sex and romance got the lowest scores in a recent survey conducted by a marriage and family ...
Rediscovering Jesus in the Christmas Madness
In a day when Frozen tree ornaments outsell nativity scenes, let's refocus on Jesus.
How to Pray With Life-Changing Boldness
What Jesus says about pushing the boundaries in prayer isn't just startling, it's ...
Uncover the Mystery of the Magi
It's a story you've likely heard thousands of times, but how much do you really know about ...
God Adores the Heart of a Praying Mother
Here's how you, much like Mary the mother of Jesus, can forge a family legacy of protection and ...
Never Ignore These Cancer Warning Signs
If you begin to experience these symptoms, it is recommended that you see your doctor right away.
Jameis Winston: 'They Will Be Held Accountable'
The Florida State University quarterback recently chastised the media and his accusers for ...
When People Hate You
Have you wondered why someone hates you without cause? Here's what the Bible says about hating ...
The Key to Understanding the Spiritual Realms of Authority
Many people try to operate in the spirit and do not understand spiritual realms. In order to ...
Why Some Jews Will Never Trust Evangelical Christians
Given the history, Jewish cynicism toward evangelical Christians is understandable. But here's ...


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Hurricane Irene: Broadway Shows Will Not Go Dark
On Friday afternoon, Disney canceled The Lion King and Mary Poppins performances scheduled for this weekend, along with other productions. For the full story, go here.
As New York City readies for Hurricane Irene, that hasn't stopped Broadway shows from continue as scheduled.
The Broadway League said on Friday that all Broadway shows that are scheduled to play this weekend will go on as scheduled, the Associated Press reports. The Off-Broadway League also added that it had not been notified of any cancellations due to the impending storm.
The New York International Fringe Festival, however, canceled all of its festivities set to take place on Sunday, which included its closing night event. Early Friday afternoon, festival organizers issued a statement saying all of the shows set to take place on Saturday have also been canceled.
"Due to the necessity of shutting down subways as of noon on Saturday, as well as keeping the roads clear for those under mandatory evacuation orders, all Saturday and Sunday performances of FringeNYC shows are cancelled," the statement read.
Hurricane Irene is expected to hit North Carolina on Saturday before moving its way up the East Coast, causing the National Weather Service to issue a hurricane watch for the Big Apple. The hurricane could hit near New York City by Sunday.
Hurricane Irene could potentially put a dent in the domestic box office this weekend, with the Washington D.C. area expected to have torrential rains and dangerous winds beginning Saturday. On Thursday, Mayor Bloomberg told city residents to be prepared to evacuate the city and ordered evacuations of nursing homes and five hospitals in low-lying areas on Friday. The subway system would also be shut down on Saturday.
Distribution executives said that it would undoubtedly be a tough weekend in the box office, with major studios in less of a bind than the independents.
"I'd hate to be opening a movie now," said one studio executive.
Several events have been canceled due to the hurricane. The Afro-Punk Music Festival, set to take place Saturday and Sunday in Commodore Barry Park, was canceled after the city rescinded event permits.
Never miss a story. Stay up-to-date with THR's Daily Headlines.
Must Reads
Michael Wolff: 8 Hollywood Predictions for 2015
Chris Pratt, Angelina Jolie, Taylor Swift and Hollywood's 26 Rule Breakers of 2014
Angelina Jolie on Ditching Her Team, Directing Brad Pitt: "A Therapist Would Have a Field Day"
Film Fighters, All in One Frame: J.J. Abrams, Judd Apatow, Bennett Miller, Christopher Nolan and Edgar Wright
Perverted Wolves, Cheating Wives and a Fired 10-Year-Old: The Dark Path to Disney's 'Into the Woods'
Chris Rock Pens Blistering Essay on Hollywood's Race Problem
Hollywood's 100 Favorite Gifts
What Hollywood Earns
Hollywood Salaries Revealed
Studio Perks of the Hollywood Exec: Home Screening Rooms, Private Jets, Huge Expense Accounts
Jessica Alba's Tears on Her Way to Building a $1 Billion Business


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Vuly Trampolines
Vuly Trampolines sets the benchmark of international trampoline excellence by creating the highest quality trampolines and accessories worldwide. Our world-class engineers, designers and safety experts work together to develop revolutionary products that are the safest and most durable on the market. They also have the world's best bounce!
Vuly Classic is available in 8ft, 10ft, 12ft and 14ft sizes, and Thunder is available in M, L and XL.
Add even more fun to trampolining with these fantastic trampoline accessories:
- Deluxe Tent: Transform your trampoline into a secret hideout or cubby house!
- Basketball Hoop: Slam-dunk and stay super safe.
- Vuly Deck: Get air and perform sweet skate tricks and flips!
- Ladder: Access to your trampoline safely and easily.
- Anchor Kit: Secure your trampoline to the ground.
Click "Visit Website" for more information. Please give us a call on 1300 667 514, or visit our showroom in Brisbane today! You can also place your order online at: http://www.vulytrampolines.com
Contact: 1300 667 514
User reviewsAdd a Business Listing FREE
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Thank you, your review has been posted.
Poor serviceBy Kylie on 20/11/2014 10:00:07 PM
I had so many issues getting the correct trampoline (two different models sent, wrong size tent sent), and the customer service was terrible - I had to keep chasing them up after they had sent incorrect product. I had to phone and email so many times - certainly not what you would expect when you have just paid over $1700 for a trampoline. Trampoline seems like a good pro (...) Read more
Half price parts, triple price delivery feeBy Mark on 14/11/2014 12:47:13 PM
Overall the product is solid and the customer service experience is pretty good as well. Come several years down the track, when you have a ripped net and water logged padding, you might remember that customers are offered replacement parts for "half price". Unfortunately you may be looking at more or less full price once the $50+ delivery fee and credit card surcharge (...) Read more
vuly trampolineBy Mel on 15/10/2014 3:11:58 PM
Purchased a thunder trampoline back in Sept for our daughter's birthday which is early October. Have had huge delays with installation, first trying to get installers contact details from Vuly and secondly missing parts which I have had to ring twice to have sent out. Unfortunately it is now 2 weeks since our daughters birthday and she has not received her present, even th (...) Read more
AWESOME!!By Russell on 30/08/2014 4:34:43 PM
Our new Vuly trampoline has been amazing the kids have been on it nearly everyday- the service was fantastic from Queensland and it is by far the springiest trampoline i have ever used!
Great Customer ServiceBy Rich on 25/08/2014 1:23:40 PM
I purchased an 8ft Vuly trampoline in December 2013. It is great value for money. My kids love jumping and spend hours entertaining themselves. The ladder began rusting after 8 months. Vuly responded to my email within 2 hours and advised it would be replaced without any fuss. Brilliant customer service and another reason to purchase from this company.
Great serviceBy Amanda on 23/06/2014 7:51:28 AM
Our new Vuly trampoline arrived interstate in 2 days, we were really impressed by the turnaround. It was quite easy to put together and our daughter adores it.
DANGEROUS - BEWAREBy Luke on 18/03/2014 9:14:22 PM
I bought a trampoline from this company in 2008. Recently, the mat, springs and joints that join the mat to the springs completely buckled. This happened when I landed on the mat from a very high jump. My body instantly collapsed and compressed, and did not bounce back up. My neck and back experienced intense pain. Six weeks later, after seeing a chiropracto (...) Read more
Surprised at serviceBy D J Neil on 10/03/2014 10:16:11 AM
I must say i was really surprised at the service and subsequent replacement of our netting. We had a concern, sent in a photo and without complaint recieved a replacement immediately. Well Done and Thank You.
Happy with the trampoline -eventuallyBy John on 9/03/2014 11:50:23 PM
Purchased a Vuly trampoline for our grandsons birthday. But experienced considerable disappointment as they mucked up the delivery doubling up on several boxes and omitting another. Fixed in 4 days but missed the birthday. The trampoline is now erected and is much loved. Disappointing initial impressions though.
Thunder - Why the spary paintBy Ron on 25/02/2014 5:49:12 AM
I was a bit miffed to get a can of spray paint the other day for my Thunder which I brought for xmas 2013. Has anyone else received this for yours? Having spent heaps on it I was a bit cranky that I'm expected to spray the whole thing! Specially as we've only had it for a couple of months!!! The letter that came with it says that my warranty won't apply if I don't do it wh (...) Read more


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Town Square
Shop Talk
Original post made on Oct 4, 2010
Read the full story here Web Link posted Friday, September 24, 2010, 12:00 AM
Comments (1)
a resident of Downtown North
on Oct 4, 2010 at 7:18 pm
It's important to know that a restaurant can be full all the time, and still fail. If the operators fail to control costs, they will spiral out of control sooner or later. Unfortunately, people who are good in the kitchen are not always good on Quickbooks.
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Spell the Secret Word: Practice Subtraction 10
If your child dreads doing math practice, try this worksheet that makes subtraction problems fun. Once he's completed the 8 problems by rewriting the equations and solving for the difference, your child will use his answers to uncover a secret word. Not only will he be able to check his work, but he'll be able to enjoy the satisfaction of completing a puzzle!
Want more? Try the rest of the worksheets in the secret word series!
Topics: Second Grade, Subtraction
Common Core: 2.NBT.B.5
Updated on Jan 21, 2010
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Our online tools make booking, managing your schedule and paying for lessons easy and hassle-free.
Access and compare detailed information about teaching style, experience, education, and more.
If for any reason you're not satisfied after your first lesson, we'll help you find another teacher or refund your entire purchase.
No matter where you live, chances are we can introduce you to an
amazing teacher in your neighborhood. You can take lessons in the
privacy of your own home or at your teacher's location. Start by
searching in your ZIP code to find teachers near you.
Learn More
What if the teacher who best fits your needs is on the other side
of the country? No problem. Our online lesson platform connects
you with any teacher, anywhere. All you need is a reliable Internet
connection, a webcam, and a microphone.
Learn More
Your search for the perfect teacher starts with the subject you'd like to learn and your ZIP code. From the list of recommended teachers, compare detailed information about each option before you make your teacher selection.
Take some time to review the teachers in our network. All of our teachers provide detailed profiles, including information about their background, specialties, and teaching style. You can also read reviews from past and current students.
Select your teacher and book online. After you book, your teacher will contact you directly to talk about your first lesson and you'll be able to manage your entire schedule through our free online account.
Take your voice to the next level. Download free video tutorials to start singing like the star you are!
Getting Started with Music Lessons guides you through selecting a teacher & preparing for your first lesson.
Kickstart your guitar playing. Download free video tutorials to learn about chord progressions, strumming, and more!
I've been teaching private lessons since 2010 and have loved helping my students learn to sight read, perform and acquire new skills and self confidence. I studied privately and then earned a Masters in Fine Art in 2004. I'm an encouraging, flexible and light-hearted individual and my teaching style includes enjoyment, skill and appreciation.
I look forward to helping you reach your goals! I encourage anyone to learn and play any genre they desire. I was trained in classical music which I find is a wonderful springboard to any type of music.
I incorporate basics that all students will benefit from and then direct them towards their goal and them help them enjoy! enjoy! enjoy!!!!!!
I have been teaching piano to students of all ages since 1992, both to individual students and groups. I taught with the Music Learning Center of Michigan. I have been a music teacher and choir director for a number of years as well. For eight years I have played the organ and piano for Church worship.
*** Lesson Details ***
Music should be appreciated and enjoyed. Lessons should be fun without sacrificing quality. This is the approach I offer to students. I focus on teaching independence through music theory and sight reading. Performance is an important part of learning so I provide two recitals every year- one for Christmas and another in the spring, at the end of the school year.
*** Studio Equipment ***
Separate room dedicated to teaching with upright piano, also has digital ...
Composer Troy W. graduated from the New England Conservatory, earning his Bachelors, Masters (cum laude) and Graduate Diploma while studying with mentor Malcolm Peyton. After spending a year studying with Lukas Foss in Boston, Mr. W. moved to Houston in 2001 where he continued graduate studies at Rice University's Shepherd School of Music.
During his time as a teacher with the Michael P. Hammond Preparatory Program at Rice University's Shepherd School of Music, Troy taught classes in music fundamentals and music theory for pre-college students. He has also served on the faculty of the Summer Institute for Piano teaching courses in Form & Analysis for pre-college students.
Troy also has maintained a private studio, tutoring and teaching private lessons in composition, ...
Robert began playing guitar in Houston, Texas at the age of 12. It was not long before he began playing in bands and played his first professional gig at age 17. Robert performed in and around the Houston area for five years before deciding to study music on the college level. He attended the University of North Texas and later attended Musicians Institute. While a student at MI, Robert was given the Outstanding Student of the Year Award for 1991-'92. Robert began teaching at MI in the guitar school (GIT) in 1993. He has played with Bo Diddley, Tim Bogert, Chevy Chase, Floyd Radford, Deacon Jones, Joe Houston and countless others. He has performed for Buddy Ebson and Chevy Chase and has partied with the Monkees. In addition to playing guitar Robert also plays and teaches bass ...
Ralph B
Thank you for viewing my profile for guitar instruction.
I also can teach and help with composition and "score to picture".
The band I currently record guitars for {A Bad Think} has been placed on the ballot by the Grammys for Best Rock Album of the year.
Kingwood, Texas
Voting Grammy member
I was born in New Jersey, and soon after moved to St. Louis where I began to play guitar at age 6 at the Mel Bay Studios from Mell Bay himself, and later from the person who taught him to play. After attending music school for a while, I moved to a recording studio in Houston Texas, where I was a session player and learned the art of recording and producing from major label producers and engineers. During this time I recorded on albums for Freddy Fender as well as ...
Zane W. starting taking lessons from Guitar Institute of technology graduate, Charlie Lair at 12 years of age and studied with him for 6 years. Zane began serious classical voice lessons when he was 18 from Dr. Paul Busselburg, and is now currently taking speech level singing.
He has taken 8 music theory courses and 8 ear training courses. Also, he is a proficient song writer.
Zane has been teaching both singing and guitar lessons for 4 years.
***He recently lost touch with most of his previous students due to working with t.v. show "The Voice" but is passionate about sharing his gift with others now that he is back in Houston.
TakeLessons is the nation's leading private lessons provider, offering customized one-on-one lessons in hundreds of subjects in over 2,800 U.S. cities, including Humble and surrounding areas.
Whether you are a beginner, intermediate, or experienced musician, you can benefit from working with a TakeLessons Instructor in Humble to make your dreams a reality. Choose from a variety of music lessons taught in the Humble area, including guitar lessons, voice lessons, drum lessons, piano lessons, violin lessons and many more! Explore our Humble teacher profiles to compare each teacher's teaching style, background, student feedback, hourly availability, and more.
TakeLessons is here to help you find the right instructor to fit your interests...
and skill level. Lessons are offered at studio locations throughout Humble, and some of our instructors will even travel to you if you prefer in-home lessons. Our teachers work with students of all ages and offer lessons for kids, teenagers, and adults. Our teachers will strive to give you a personal one-on-one learning experience with a customized lesson that exceeds your expectations. In fact, we are so committed to your satisfaction that we offer all new customers a 100% Money Back Guarantee on your first music lesson.
Get started with music lessons in Humble today! TakeLessons student counselors are standing by and ready to help; simply give us a call at 800-252-1508. You also have the option of selecting your teacher and signing up for private classes online. Get ready to learn, grow, challenge yourself, and open your life to the advantages of ongoing education through lessons.
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"My daughter's wedding was weeks away and I had never been able to dance a step. With Jenny's help, I came further than ever before in such short time in any subject."


text:
Immunohistochemical analysis of O6-methylguanine-DNA methyltransferase in human melanoma in comparison with skin squamous cell carcinoma
- Yasuhito Kokunai,
- Motomu Tsuji,
- Yuko Ito,
- Teruo Kurokawa,
- Yoshinori Otsuki,
- Shinichi Moriwaki
- … show all 6 hide
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Alkylating agents, often used for chemotherapy in patients with melanoma, can produce O6-alkylguanine (O6AG) which is related to tumor cell killing after treatment with alkylating agents. O6AG is effectively eliminated by O6-methylguanine-DNA methyltransferase (O6MGMT) and its level is correlative to the resistance to alkylating agents. However, little is known about the relationship of O6MGMT to the characteristics of melanoma. This study investigated the expression of O6MGMT in 12 melanomas and compared it with that in 11 skin squamous cell cancers (SCCs) immunohistochemically to evaluate the O6MGMT activity in melanoma and its clinical significance. All of the SCC samples had high O6MGMT expression, while the expression of O6MGMT in melanoma was diverse and 4 out of 12 samples had no or extremely low O6MGMT activity. Out of 6 lesions obtained from metastasis, 4 had a high O6MGMT activity. Two out of 3 cases with a low O6MGMT activity in each primary lesion did not show any evidence of metastasis or local recurrence. The evaluation of O6MGMT activity in melanoma may, therefore, be useful to determine the characteristics of tumor in each melanoma case. In addition, the present study implies the possibility of selective cancer chemotherapy for melanoma in the near future.
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- Hassel JC, Sucker A, Edler L, Kurzen H, Moll I, Stresemann C, Spieth K, Mauch C, Rass K, Dummer R, Schadendorf D (2010) MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome. Br J Cancer 103:820–826 CrossRef
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- Christmann M, Verbeek B, Roos WP, Kaina B (2011) O6-methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry. Biochim Biophys Acta 1816:179–190
- Qian XC, Brebt TP (1997) Methylation hot spots in the 5′ flanking region of the O6-methylguanine-DNA methyltransferase gene. Cancer Res 57:3672–3677
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- Ma S, Egyhazi S, Ueno T, Lindholm C, Kreklau EL, Stierner U, Ringborg U, Hansson J (2003) O6-methylguanine-DNA-methyltransferase expression and gene polymorphisms in relation to chemotherapeutic response in metastatic melanoma. Br J Cancer 89:1517–1523 CrossRef
- Glassner BJ, Weeda G, Allan JM, Broekhof JL, Carls NH, Donker I, Engelward BP, Hampson RJ, Hersmus R, Hickman MJ, Roth RB, Warren HB, Wu MM, Hoeijmakers JH, Samson LD (1999) DNA repair methyltransferase (MGMT) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents. Mutagenesis 14:339–347 CrossRef
- Middleton MR, Lunn JM, Morris C, Rustin G, Wedge SR, Brampton MH, Lind MJ, Lee SM, Newell DR, Bleehen NM, Newlands ES, Calvert AH, Margison GP, Tahtcher N (1998) O6-methylguanine-DNA-methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma. Br J Cancer 78:1199–1202 CrossRef
- Ma S, Egyhazi S, Martenhed G, Ringborg U, Hansson J (2002) Analysis of O6-methylguanine-DNA methyltransferase in melanoma tumours in patients treated with dacarbazine-based chemotherapy. Melanoma Res 12:335–342 CrossRef
- Ma S, Egyhazi S, Ringborg U, Hansson J (2002) Immunohistochemical analysis of DNA repair protein and O6-methylguanine-DNA methyltransferase in melanoma metastases in relation to clinical response to DTIC-based chemotherapy. Oncol Rep 9:1015–1019
- Rietschel P, Wolchok J, Krown S, Gerst S, Jungbluth A, Busam K, Smith K, Orlow I, Panageas K, Chapman P (2008) Phase II study of extended-dose temozolomide in patients with melanoma. J Clin Oncol 26:2299–2304 CrossRef
- Balch CM, Gershenwald JE, Soong SJ, Thompson JF, Atkins MB, Byrd DR, Buzaid AC, Cochran AJ, Coit DG, Ding S, Eggermont AM, Flaherty KT, Gimotty PA, Kirkwood JM, McMasters KM, Mihm MC Jr, Morton DL, Ross MI, Sober AJ, Sondak VK (2009) Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 27:6199–6206 CrossRef
- Egyhazi S, Margison GP, Hansson J, Ringborg U (1997) Immunohistochemical expression of O6-methylguanine-DNA methyltransferase in human melanoma metastases. Eur J Cancer 33:129–134 CrossRef
- Moriwaki S, Nishigori C, Takebe H, Imamura S (1992) O6-alkylguanine-DNA alkyltransferase activity in human malignant melanoma. J Dermatol Sci 4:6–10 CrossRef
- Augustine CK, Yoo JS, Potti A, Yoshimoto Y, Zipfel PA, Friedman HS, Nevins JR, Ali-Osman F, Tyler DS (2009) Genomic and molecular profiling predict response to temozolomide in melanoma. Clin Cancer Res 15:502–510 CrossRef
- Kleibl K (2002) Molecular mechanisms of adaptive response to alkylating agents in Escherichia coli and some remarks on O6-methlyguanine DNA-methyltransferase in other organisms. Mutat Res 512:67–84 CrossRef
- Kage H, Christmann M, Kern MA, Dietel M, Pick M, Kaina B, Schadendorf D (1999) Expression of DNA repair protein hMSH2, hMSH6, hMLH1, O6-methylguanine-DNA methyltransferase and N-methylpurine-DNA glycosylase in melanoma cells with acquired drug resistance. Int J Cancer 80:744–750 CrossRef
- Luo Y, Dallaglio K, Chen Y, Robinson WA, Robinson SE, McCarter MD, Wang J, Gonzalez R, Thompson DC, Norris DA, Roop DR, Vasiliou V, Fujita M (2012) ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells 30:2100–2113 CrossRef
- Title
- Immunohistochemical analysis of O6-methylguanine-DNA methyltransferase in human melanoma in comparison with skin squamous cell carcinoma
- Journal
Medical Molecular Morphology
Volume 47, Issue 1 , pp 8-13
- Cover Date
- 2014-03-01
- 10.1007/s00795-013-0030-3
- Print ISSN
- 1860-1480
- Online ISSN
- 1860-1499
- Publisher
- Springer Japan
- Additional Links
- Topics
- Keywords
- Alkylating agent
- DNA repair
- Melanoma
- O6-alkylguanine
- O6-methylguanine-DNA methyltransferase
- Skin squamous cell carcinoma
- Industry Sectors
- Authors
- Yasuhito Kokunai (1)
- Motomu Tsuji (2)
- Yuko Ito (3)
- Teruo Kurokawa (1)
- Yoshinori Otsuki (3)
- Shinichi Moriwaki (1)
- Author Affiliations
- 1. Department of Dermatology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan
- 2. Department of Pathology, Osaka Medical College, Takatsuki, Japan
- 3. Department of Anatomy and Biology, Osaka Medical College, Takatsuki, Japan


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Pablo Martinez Monsivais, AP
"Free" — in regards to health care, housing or food — is such an interesting idea. The thought that having basics without cost sounds tempting to anyone who is struggling, but where does that "free" thing come from?
If we are talking about health care, it seems especially inviting. Consider, however, the cost that the doctor put into his education in time, energy and actual money. Ask him to give that away for free, and he becomes an unpaid servant to those he is treating.
His investment gains him nothing.
But we can get the costs paid by the government or someone else, some would answer. Who is the government but other people who pay taxes, or that someone who gives donations to charity.
Having the state or other government agencies pay for things can easily and directly be equated to having your neighbor pay for your things. We pay with money in our current system, either from our own accounts or from the accounts of others.
Things — some of them even important and necessary — do not come free, even if we would like them to.
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|Hotel Urune Barrio Txakale, 8, 48392 Muxika, Spain (3 miles from Marmiz)
Score from 74 reviews: WonderfulThis charming 18th century house is in the Urdaibai Biosphere Reserve, just outside Muxika. The simple rooms feature exposed stone walls and enjoy views of the beautiful surrounding landscape. More…
" The owner and staff exemplify the wonderful Basque hospitality while providing exceptional service. This is an old farmhouse in a great location that was well renovated - the rooms and common areas retain ... "
$114 Average price per night
|Eco Hotel Mundaka Florentino Larrinaga 9, 48360 Mundaka, Spain (7.8 miles from Marmiz)
Score from 186 reviews: Very good There is 1 person looking at this hotel.Hotel Mundaka is situated in central Mundaka, just 100 metres from one of Europe's famous surfing destinations. More…
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|Hotel-Apartamento Rural Atxurra Barrio Arronategi s/n, 48370 Bermeo, Spain (8.3 miles from Marmiz)
Score from 249 reviews: WonderfulHotel-Apartamento Rural Atxurra has an ideal setting in the Urdaibai Natural Park, near the Basque coastal town of Bermeo. It has a terrace and a garden, and offers free parking. More…
" Location, views of the coast and mountains and the accommodation was also excellent. The evening meal with an excellent house wine which was included in the price and the very good choices for breakfast "
|Zubieta Portal de Atea S/N, 48280 Lekeitio, Spain (8.4 miles from Marmiz)
Score from 204 reviews: ExcellentThe traditional 18th Century building of Hotel Zubieta is situated in Lekeitio. All rooms are uniquely named and decorated, and have free Wi-Fi and satellite TV. More…
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|Palacio Urgoiti Arritugane, s/n, 48100 Munguía, Spain (10.3 miles from Marmiz)
Score from 232 reviews: Very good There is 1 person looking at this hotel.This 17th-century palace is 7.5 miles from the center of Bilbao, 3 miles from Bilbao Sondika Airport. All guests enjoy free Wi-Fi and free parking on site. More…
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$88 Average price per night
|Aisia Derio Hotel Museo Spa Camino Ereaga s/n. Parque Tecnológico Edificio 806., 48160 Derio, Spain (11.2 miles from Marmiz)
Score from 256 reviews: Review score There is 1 person looking at this hotel.The hotel is located within the Parque Tecnológico de Zamudio, just 5 minutes from Bilbao airport and 15 minutes from the town centre. More…
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Barack Obama and John McCain, the US presidential candidates, have squared off in their third and final - and most heated - televised debate.
With fears over the US and global economy dominating viewers' minds, the pair repeatedly clashed at the Hofstra University campus on Long Island in New York state on Wednesday.
Rob Reynolds, Al Jazeera's senior Washington correspondent, said some of the exchanges between the pair were "the most genuine - and the angriest - in all three debates".
McCain was chosen to open the debate and, asked by Bob Schieffer, the debate moderator, how he would tackle the current economic problems, he launched off by saying they needed a "short-term fix and a long-term fix" to solve the current problems.
He said: "Let's take $300bn and go in and buy up those [bad] mortgages.
"We've got to reverse this, I'm disappointed that [Henry] Paulson [the US treasury secretary] and others haven't made this their priority."
'Worst crisis'
Obama responded: "Everyone understands we are experiencing the worst crisis since the Great Depression."
He said the bailout financial plan was "an important first step" but added "what we haven't yet seen is a rescue package for the middle class".
Follow our coverage of the debate live on Al Jazeera's Twitter service
He added it was necessary to have a rescue package for the middle class, with a focus on boosting domestic employment and offering families cuts in taxation, adding that the long-term challenges were to "fix energy policy, fix healthcare and invest in the education system".
The debate quickly took on a hard edge, with McCain aggressively focussing on comments made by "Joe the plumber" - an American voter Obama addressed during his campaigning - to try and highlight differences between the pair.
He said to Obama: "What you wanna do to Joe the plumber is to have tax increases and not let him realise the American dream [of home ownership]."
Aggressive tack
Asked by Schieffer if they would cut US government spending plans because of the economic crisis, McCain said "we need to freeze spending" while Obama answered "we need to cut programmes that don't work".
There was tension between the pair, with McCain taking an aggressive stance towards Obama.
McCain declared: "I'm not George Bush."
Asked about negative campaigning that had reportedly marred both candidates' campaigns, Obama said McCain "runs negative campaigns" while McCain said "Obama has double standards".
McCain said: "It's been a tough campaign ... Obama has spent more money on negative political ads then any other campaign in history and I can prove it.
Addressing his rival, he said: "You didn't keep your word, you didn't tell the American people the truth."
'Failed policies'
Obama responded by saying: "The American people cannot afford four more years of failed economic policies, we need to talk about what's most pressing to them - the economic crisis.
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Rob Reynolds said: "I thought McCain's best moment was saying he's not Bush and if Obama wanted to run against Bush, he should 'have done it four years ago'.
"McCain looked pretty strong; Obama jabbed back that McCain's policies were the same as Bush's, but he didn't look as strong."
Schieffer asked both candidates: "Why is your vice-presidential running mate better than your opponent's?"
McCain said his running mate, Sarah Palin, was "a role model for women" while Obama said Joe Biden had "huge experience".
Schieffer queried how either of the pair would reduce US dependence on foreign oil in their first term.
McCain said he would seek to invest in nuclear power, while Obama said he would promote alternative energies.
Rob Reynolds said: "The most genuine - and the angriest - exchange between the two ... was on Schieffer's question about negative campaigning. Obama kept his cool but McCain seemed to get angry towards the end.
"Overall, I think it was a strong performance by John McCain - he appeared to be aggressively questioning Obama on a number of issues, without really appearing offensively aggressive.
"Joe the plumber - he is the stand-in for the middle class American who's worried about the economic meltdown - was the person that both McCain and Obama were trying to reach."
He said the pair showed "very controlled emotions, especially Obama. He didn't make any mistakes".
"His job was not to step on himself. McCain's job was to really not appear unpleasant ... and I think both of them did their jobs."
Under pressure
McCain, the Republican candidate, was under pressure to put in a strong performance to help reverse his position in the opinion polls.
The debate was held amid opinion polls that show Obama gaining strength nationally and also in battleground states.
The lastest New York Times/CBS poll showed Obama on 53 per cent and McCain on 39.
The debate was the last big event in the campaign before both candidates hit the trail for the two-and-a- half week drive to the elections on November 4.
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"It's tough to remind myself that it's still early, especially days like that where it wasn't sharp command-wise by any means. I felt like I did a good job making pitches when I had to get out of jams. That's what I'm going to focus on right now, getting that mental aspect back."
Related quotes
"We forget ourselves and our destinies in health, and the chief use of temporary sickness is to remind us of these concerns."
"This reminds me, Godmother, to ask you a serious question. You are as wise as wise can be (having been brought up by the fairies), and you can tell me this: Is it better to have had a good thing and lost it, or never to have had it?"
"The (basketball) coaches bring it up a lot, especially when they are putting us through our drills. They'll remind us that we didn't finish the job. I just tell him, 'C'mon, Coach. Don't talk like that. That's pretty harsh.' But they know how to motivate us."
"Every part of his game is very sound, very sharp. He's going to be tough to beat tomorrow. But I believe I've got the tools to beat him."


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15 results for "pick six"
Halftime analysis: Texas A&M 24, Baylor 14David Ubben
COLLEGE STATION, Texas -- Weird end to the half when Robert Griffin III appeared to throw what would have been a game-changing pick-six, but the ball hit the ground before it was kicked. Griffin delivered a big hit at the end of the play, but the ...Blog | October 15, 2011
Landry Jones can prove he's a different QBDavid Ubben
GLENDALE, Ariz.--We've seen that before. A little over a month ago, Landry Jones threw a pick-six in the Sooners' biggest game of the year at that point, helping Oklahoma State linebacker Shaun Lewis bring the Cowboys to within four points. His...Blog | January 01, 2011
OSU mistake allows impressive Jones reboundDavid Ubben
STILLWATER, Okla. -- Landry Jones bounced back from his worst throw of the night, an easy pick-six to Oklahoma State's Shaun Lewis, with two of his best passes. The first was a 16-yard throw to Cameron Kenney to convert on a 3rd-and-9. On the next pl...Blog | November 27, 2010
Aggies' bandwagon looking creakyDavid Ubben
Jerrod Johnson was voted preseason Big 12 Offensive Player of the Year, but he hasn't looked like it against Florida International. Johnson just threw a pick-six to Anthony Gaitor that has Texas A&M trailing 20-6 late in the third quarter at home...Blog | September 18, 2010
Wrapping the Big 12 afternoon gamesDavid Ubben
Nebraska 56, Washington 21: What a dominating second half from the Huskers on both sides of the ball. The defense limited Jake Locker and forced him into a pick-six that gave them a four-touchdown lead. And we can probably count on seeing Taylor Mart...Blog | September 18, 2010
Eddie Jones' pick six boosts Texas to 47-0 leadDavid Ubben
WACO, Texas -- A 60-yard interception return for a touchdown by Texas defensive end Eddie Jones accounted for the first points of the second half, boosting the Longhorns to a 47-0 lead with 7:37 left in the game. Baylor quarterback Nick Florence a...Blog | November 14, 2009
Thomas adds another pick-six adding to Texas' defensive feeding f...David Ubben
Posted by ESPN.com's Tim Griffin STILLWATER, Okla. -- Texas is turning this one into a laugher after Earl Thomas' 31-yard pass interception return for a touchdown extended their lead to 34-7. It marked Thomas' conference-leading sixth intercept...Blog | October 31, 2009
Curtis Brown's pick-six extends Texas' leadDavid Ubben
Posted by ESPN.com's Tim Griffin STILLWATER, Okla. -- Curtis Brown provided some cushion for Texas with a 77-yard pass interception return for a touchdown, extending Texas' lead to 17-0 over Oklahoma State with 6:21 left in the second quarter. ...Blog | October 31, 2009
Big 12 has a handful of value picksDavid Ubben
The Big 12 will likely have a pair of top-10 picks tonight and five selections in the first round, but there will still be six more rounds over the next two days, and plenty more Big 12ers will have a new home soon. Middle and late-round picks are...Blog | April 28, 2011
Early success for Big 12 at next levelDavid Ubben
The Big 12 had a record-breaking performance in the 2010 NFL Draft, landing nine first-round picks and five of the first six picks. A few of those picks have spent the first half of the season proving they were worth the hefty first-round price ta...Blog | November 04, 2010
Sorting out the draft for the Big 12David Ubben
The Big 12 had 30 players drafted over the weekend, fifth most among the major six conferences. Conference Total picks Picks per team SEC 49 4.08 Big Ten 34 3.09 Pac-10 28 2.8 ACC 31 2.58 ...Blog | April 26, 2010
Pick finishes spring with flurryDavid Ubben
Entering spring, Kale Pick was one of six quarterbacks vying to open the Turner Gill era at Kansas as the starting quarterback. He took his divvied-up snaps and by the final week of spring, joined Jordan Webb as the two front-runners for the job. ...Blog | April 26, 2010
Big 12 set to flex in NFL draft's first roundDavid Ubben
We're only a few hours away from tonight's first round of the NFL draft, one that could be unprecedented for the conference. As many as five of the first six picks could come from the Big 12. Oklahoma's Sam Bradford is the assumed first pick. D...Blog | April 22, 2010
Four from Big 12 to attend draftDavid Ubben
The Big 12 could have as many as six players drafted in the first 10 picks of the first round of the NFL draft on April 22. I haven't mentioned this on here yet, but four have confirmed they'll attend: Gerald McCoy, DT, Oklahoma Russell Okun...Blog | March 31, 2010
Big 12 picks: Look for more struggles vs. Big EastDavid Ubben
Posted by ESPN.com's Tim Griffin The Big 12 will be on display the next two nights as underdogs against two powerful Big East foes. After losing two games in six days to the Big East, the conference is looking for a quick turnaround. Here are my pick...Blog | September 18, 2008


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Who We Are
Welcome to Valley Charter Middle School! We are a free, public charter school serving Los Angeles' San Fernando Valley. Launched in August 2011, we continue to grow and commit ourselves to ensuring that every student achieves success in his or her learning. We value community, diversity, responsibility and academic excellence. Our classrooms are small, our environment warm, and our instruction dynamic. Feel free to browse through our website to learn more about our program.
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Valley Charter School presents an important meeting for all parents December 8 at 7:00 in the VCES sanctuary. RSVP by emailing firstname.lastname@example.com
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School tours are a great way to meet the principal, get your questions answered, and see learning in action at Valley Charter Middle School. Please email us to book a tour today.