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Kissimmee, United States of America
3205 Running Bear Way, Indian Wells (office address only), Lake Buena Vista, Kissimmee, FL 34746, United States of America – Show map
Excellent location – rated 9.1/10! (score from 226 reviews)
Rated by guests after their stay at Laguna Villas.
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279 properties in Kissimmee
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226 verified reviews
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Laguna Villas's staff speaks: English
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BBQ Facilities, Outdoor Pool
Tennis Court
WiFi is available in all areas and is free of charge.
Free public parking is available on site (reservation is not possible).
Non-smoking Rooms, Heating, All Spaces Non-Smoking (public and private), Air Conditioning
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Summer Bay Orlando by Exploria ResortsLatest booking: 2 hours ago There are 7 people looking at this vacation home.
Encantada Resort by E ManagementLatest Booking: December 21 There is 1 person looking at this holiday home.
We loved the location so close to Epcot. The house was impeccable with cleanness, towels, space, quiet and full size kitchen. We spent most of our eating just for breakfasts at home.
Location was great. Quiet well kept neighborhood. The house itself spacious and clean, very comfortable.
TV's and all major kitchen appliances could use an upgrade. Wi-fi to slow to stream movies.
Very convenient to the parks and a Walmart for what you forgot. House well equipped with everything you could possibly need in the kitchen. It is an easy in and out to the highway, yet close to everything. Plenty of space for a family of 8.
Nothing really.
recreational facilities. Size of house. cleanliness and quiet community.
these villas are ideal for someone who doesn't drive in America ,it is minutes away from Wal mart and lake Buena vista shopping outlet is a 15 minute stroll ,we go for the shopping so we go back every year and use the same villas ,they are value for money ,
the unit could benefit from a re furb but you get what you pay for and we go every year so its not too bad
This house offered a combination of great location and value. Tons of space and a pool for great price. House was very neat and inviting.
land lord office staff attitude private pool internet speed location
rude owner representative (the lady) old and in-comfort furniture very very very limited TV channels
I stayed for 3 weeks i like the Location , every thing is close from indian hills propertey , Also i got a lake side 3 bedroom, the villa was clean every thing is provided , if the furnture is new it would be aosome ,
Like every one said the furnture is outdated .
facility, equipment, own pool
Narrowness to the neighbourhood
Some of the appliances didn't work.,nor did the key for the pool. The dressers were broken.Other than that we had great time.
Awesome location to Disney and shopping right down the road! Very clean, friendly neighborhood. Palm trees up front, a pool out back, great place!
Poor WiFi reception
Private swimming pool Lots of space Perfectly equipped kitchen/house
I loved the location because it was close to all of the activities and town.
I was not happy with the air, We were not able to control it so it was uncomfortable at night. The pool have no pump to keep the water moving.
There wasn't anything I did not like!
Not really anything
The clean up lady was very nasty
Everything We Needed Was Right There. House Was Spacious & I Had 5 People With Me. Close To Everything
Nothing. Everything Was Good. Luv Staying Here
We loved everything. Great place to stay. Definitely will come back.
Loved the house The staff was very friendly.
The Internet connection was too slow.
Tv's could have been more up to date
I've never stayed in a villa before but definitely will consider for my future trips. There was a lot of space, privacy, and comfort for very good price. The pool was clean and villa was well furnished.
One of the Remote controls for the TV's was not working. Thankfully the other remote could work both TV's.
The price was reasonable and we were close to a lot of places. Walmart, Nike store, etc. Also my kids enjoyed access to the community pool!
The furniture was old fashion :) and closet doors weren't hanging to well, we stayed a week so we used the closet space! That's all though!
It hit every mark - I'll definitely using them again and won't hesitate to advise family and friends - thank you
Plenty of space and privacy for large family. Comfortable furniture and beds with lots of linens. Very clean. Location was close to many restaurants, stores and Disney World without having to travel the congested interstate.
The Laguna ad projects the pool location as being close within a villa setting. The pool is actually a gated "neighborhood" park with limited access and not so close.
The private pool.
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I want to give my kids the world….but not in the sense of every material possession they could dream up. I want to give them the world – and understanding of the world and how they fit into it all. Geography. Culture. People. History. With a month long road trip still fresh on our minds, we are diving into US Geography and history this year. There is something incredible about watching my kids, at different levels, understand where they 'are' in the world. It is a beautiful thing. It is powerful thing. And, lucky for me, US maps are all the rage these days. Everywhere the kids look they see outlines of states and our country. Decor trends are making homeschool easy!
My oldest is aiming to freehand the US map by the end of the school year. We watched the following video together and I was completely inspired to be able to freehand the US map too. It is long, but so amazing to me. My kids want to watch it over and over again. I suggest enlarging it to your full screen size.
So inspiring, right?!
If you are looking for more US map inspiration, here are a few I pinned:
All this map tracing and state studying is getting us all a little anxious for another roadtrip. Our list of places to visit just keeps growing….what are some of your favorite US destinations?

subset: commoncrawl


text: ESPN Feed: champions classic http://assets.espn.go.com/i/tvlistings/tv_espn_original.gif ESPN en-us 10 ESPN Inc. http://espn.go.com/ Copyright 2010 ESPN Inc. Coming off a dazzling final-round 61 to clinch her first victory of the year, Inbee Park has rediscovered the putting magic that brought her three major titles last year. The timing couldn't be better.]]> June 18, 2014 14:39:49 PDT Jennie Finch, Stefanie Dolson, Swin Cash and Heather McPhie celebrate the 10-year anniversary of the release of "Mean Girls" by performing their favorite quotes.]]> April 29, 2014 09:09:27 PDT Coming off a runner-up finish, she's the defending champion for this week's State Farm Classic and the LPGA Championship in two weeks.]]> June 07, 2011 13:13:29 PDT


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Yes, that sounds right. I usually use about a lb of sugar/gal of finished soda. That's the ratio for how much sugar is in kool-aid, so it's not unheard of.
Find Recipes on my blog: The Homemade Soda Expert I'd love some feedback!
Now Available from Quarry Books -- Making Soda at Home: Mastering the Craft of Carbonation Like on Facebook!, Follow on Twitter, Add to Goodreads
Thanx. So I did 2 teaspoons in 30 oz of carbonated water and ended up using 20 drops of extra concentrated Ezsweetz. This received approval from the taste testers. Though my daughter really couldn't tell as we started adding sugar if it was lacking flavor or sugar as compared to the control batch.
On to other flavors once we get through these batches. Though right now I only have Cherry, Black Cherry and Vanilla besides the Orange, Cream and Root Beer. Coming in a few days are Lemon Lime, Ginger Ale, Grape, Sarsaparilla, Orange Dream and Chocolate Raspberry. So I'll probably try Orange and Cream again using these proportions. If no good, we'll make syrup for snow cones.


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-Jason & Linda
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Live like Fire, and does whatever you want in a life, does good with someone without any expectations.
i m innocent baby and funtastic guys for love and patience for the time bein .
I am humble,gentle, funny, jovial, friendly. I just love to meet people of different races cos I'm not a racist. I love making people around me glo…
One of my favourite qoutes (from Dune) is this:
"Eternity swings on flesh, thought and emotion. If we deny the need for thought, we lose the power…


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"Misinformation be damned – when you're a chaos witch, every myth is valid." Love this! I agree with Deborah: many of us are "fee
There seems to be a lot of this going around :-). Thanks for voicing it so beautifully. Fatigue definitely saps our ability to to
At the risk of sounding like Bill Clinton, "I feel your pain." The "2X4 school of enlightenment" seems to apply to many of us. Y
Dearest Lee - Wowsa! What a blog! I so appreciate your openness; your honesty, and your soul-searching. You do truly seem to be
Thank you for writing this piece. I am going through a liminal time as well, and this is just the sort of thing I needed. Blessi
Antipodean Witch: Weaving the craft down under
General Blog Description: Exploring Southern Hemisphere neo-pagan practice and culture from the point of view of a progressive witch living south of Perth, Western Australia.
Lee Pike
I think I am a little ill.
I've noticed my ailment when I have been visiting the shops recently (the local shopping mall, for those playing in the U.S.A). Rather than sneer or glare at the usual proliferation of Christmas decorations that are decking the halls and the delicious treats (Pfeffernüsse! Get in me) that are sitting on shelves in early October and November, I've been smiling to myself. Smiling! Carols are playing over the speakers and I don't mind at all. In fact, I'm trilling the yuletide carols. Where did the Grinch go of Christmas past?
I've got the fever. Xmas fever!
Christmas is an awkward celebration whichever way you turn it when you live south of the equator. For starters, those snowglobes become a little irrelevant and more than a few items from traditional Christmas iconography is rendered obsolete in the Australian context. I'll allow my dear readers to connect the dots and refer you to some of my previous blogs about the Summer Solstice and how it collides with Christmas in the Southern Hemisphere. Most Aussies grin and bear it. We throw a few prawns in the barbie, sit in the 40°C heat and whinge a little and carry on with the commercial abomination of Western Christmas over-indulgence. Many of us, including me usually, absolutely hate it. It's crass, it's inconvenient, and it's often overrated. The expectations culminate in a hangover of overeating, exhaustion, and familial resentment.
This year, I'm really enjoying it, and I'm really looking forward to Christmas. I can't pin down exactly why. After a year of largely stepping away from the Wheel of the Year, I'm ready to launch myself straight back into it, and I'm ready for a little bit of anarchy while I'm at it.
This is going to take the form of indulging a 'flipped' Wheel but spreading it thick with a little applesauce that only a Discordian can bring. Some demons are coming to the party and I am going to embrace all environmental aspects of the season. This includes the natural environment: the Summer Solstice, and the fey energies that are embedded within. An acknowledgement of the polar opposition within the Winter Solstice, and the time of turning inward and contemplation that this time of year brings. We live on one planet and to dichotomise things is starting to serve me no longer, and I am beginining to look at things from a more global perspective. The cultural environment, too, will play a significant role: my black Christmas tree will receive a heap of trimmings this year that are going to be a little unexpected but a whole lot of fun. Beginning with Jack from The Nightmare Before Christmas.
My plan is to both observe and celebrate the opportunity for revelry and retreat that this time of year brings for me. Sumsol celebrations will be held at my home with my coven, and I am really looking forward to some dastardly plans that will be enjoyed with much merriment, a lot of the colour red, and maybe a little bit of sun, sand and surf.
Wish me luck as I move on from my self diagnosis and jump into the treatment that holiday fever demands!
Upon my first flush of dedicating myself as a witch, the very first sabbat I celebrated as a solitary practitioner, before I had found my coven, was Imbolc. I had done enough reading of neo-pagan literature after poaching the stacks in my local town library and I was keen to get my Wheel of the Year on. Bright eyed, and very bushy tailed.
It was most of a decade ago now, but I remember the little ceremony well; it involved a small paper clay boat with a ram's head that I had carved and fired, dipped in a golden butter-coloured glaze that seemed to perfectly suit my purposes. In the boat I placed some offerings for the sabbat; there were some white chocolate dipped raspberry licorice bullets, some sprigs of red geranium, and a splash of strawberry port from a berry farm in the south. I 'launched' my boat into my front garden which had been freshly planted with some baby rosemary and sage and protected with moonstone which glimmered in the early morning sunlight. I burned candles and meditated and felt a flicker of something that has stayed with me and returns every August. My practices ever since then have always been as eclectic, and sometimes just as elusive: but the whimsicality and solemnity of the ritual permeates my memory.
The return of Spring is not felt with obvious sign or herald in my home country as it is in other lands. The climate here is Mediterranean and warm most of the time, and the temperatures on a sunny August day could possibly be mistaken for a heatwave in some Northern Hemisphere climes. This year, thankfully, we have received some rain and Winter feels like she has finally 'arrived' after a long, and dark, wait. There is certainly a change to be felt in the air, though. A Quickening. The land stirs beneath my feet with a note of potential that was not there before, and the feelings of dormancy have been banished as the downhill push into warmth begins. Nights will be cold, if not the coldest, of the year, but there is still a sense of 'spring' under the earth and birds begin to be a little bit more noisy than usual. The rains have freshened the landscape and weeds and winter grasses are flourishing with abandon. Very soon, the land will burst forth with every colour of the rainbow as if the rainbow snake of ancient dreaming has pierced some crystal somewhere and has shattered into a million pieces and scattered across the land. The magic will sing again, but until then, we wait. And watch.
Photo credit: Cowslip orchard from Western Australia, retrieved from http://ournomadicways.blogspot.com.au/2011/10/wildflowers-of-wa-part-3.html
Before one decides to make the big leap and attend their first pagan event, one's imagination conjures up all sorts of images about the sorts of people they will meet and the experiences they will have. If you're prepared to eliminate any romantic notions and be realistic about the people you might meet, you will do well. An open mind and tolerant spirit is the best attitude to adapt as there are going to be people who, regretfully in some ways, snugly fit into stereotypes which might be a little too familiar. For the Australian pagan that stereotype is going to be: the bogan. Bogans love witchcraft, Wicca and paganism and are drawn to it, like moths to a flame. Because of this, you might find you are swamped by bogans at pagan events, a horrifying prospect for an inner city, soy-chai-latte-sipping hipster witch.
Bogans are firmly entrenched in Australian culture and their kin are the 'rednecks' in the U.S. or perhaps 'chavs' in the U.K. They are symptomatic of middle-class white cultural cringe but mostly I think bogan identification is harmless and taken with a good shake of humour. The Things Bogans Like website tells us that "the bogan today defies income, class, race, creed, gender or logic". The negative aspects of the stereotype, such as willful lack of education or general racism (in the form of cultural appropriation) and bigotry, unfortunately does make an appearance in the pagan bogan, or as very artfully coined by Galloway of the excellent blog Galloway & Daracha, the 'pogan'....
For many witches and pagans, one's practice is deeply connected to the land. It is in this that the oft-used, and sometimes contested moniker of 'earth-based spirituality' originates, and whilst I have a lot more to say about the idea of what 'earth-based' actually means in the context of witchcraft, for many, it has literal interpretations.
The turning of the Wheel and the observations of the Sabbats as framed by contemporary neo-paganism is one that links in movements that are both solar and earthly. Cultures live and die by the weather and the elements, even today in our world of modern conveniences, and this is something that many neo-pagans seek to tap back into, in order to weave meaning into our lives and to join in the dance that strums throughout the All. We gather on the Sabbats to celebrate the changes and to honour the deities who stride the land with us, and we feel and honour a connection that is deep and sacred. The waxing and waning of the planet matches the waxing and waning in both our lives and in the cosmos; in the Beyond, and Between. As the veils shimmer and lift, rise and fall, we dance in our circles and break bread with each other and with our Gods, however we view them to be....


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Abstract available in
Claims available in
Description (OCR text may contain errors)
APPLICATION flLED JAN. 6| I913.
Patented Mg. 15, 1916.
Application filed January 6, 1913.
T 0 all whom it may concern:
Be it known that T, WALTER O. PELHAM, a citizen of the United States, and a resident of the city of Monett, in the county of Barry and State of Missouri, have invented certain new and useful Improvements in Tension Devices for Hitching-Straps; and I do hereby declare that the following is a full, clear, and exact description of the same.
My invention relates to tension devices for hitching straps, and has for its object to provide certain improvements in the construction of the same, as will be hereinafter more definitely pointed out and claimed, reference being had to the accompanying drawing, in which Figure 1 is a view in side elevation of my improved device, showing the same in use in connection with a horse. Fig. 2 is an enlarged central longitudinal sectional view of my improved device.
Similar numerals of reference denote corresponding parts in the two views. I
The device embodying my invention may be attached with the head stall 1 of the halter or bridle at one end, and the tie strap 2 connected at the other, as indicated in Fig. 1. Said device, as shown in Fig. 2, comprises a casing 3, which may be constructed of metal tubing, cut the proper length, and flanged at one end at 4, said casing having fixed in its other open end a head 5 to which are attached the ends of guide rods 6, the same being connected to form a yoke or U member, said rods extending at their yoked ends through apertures in a head stop 7, which latter normally abuts against the flanged portion 4 of the casing 3. Fixed in a central bore 8 in said head stop 7 is a rod 9, the same extending freely through the head 5 at the opposite end of the device, and terminating in an eye 10 to which the halter 2 is to be attached. Disposed in the casing 3, and contacting at its ends against the head stop 7 and the stop 5 is a coiled spring, the same surrounding the U member 6, and serving normally to retain the parts in the position shown in Fig. 2.
The operation is as follows: The device Specification of Letters Patent.
Serial No. 740,373.
embodying my invention may be connected in the tie strap or rope at the free end of'the tie strap, or at any point in the length of the tie strap, as preferred, and when in use, as illustrated in Fig. 1, is inert under normal conditions. When the horse erks its head, however, from any cause, bringing any stress upon the tie strap, the stress is yieldingly imparted thereto, the spring acting to absorb the excess stress to prevent a sudden jerk on the tie strap, the effect being to permit the lengthening of the connection between the horses head and the post (or other fixed point) to which the strap is tied, sufficiently to prevent injury to the tie strap and at the same time to afford a strong and yielding pull upon the horses head to bring it back to normal; that is to say, the efiect is substantially the same as when the tie strap is held in the hand. A sufficient yielding is afforded to overcome the stress of the jerk or pull of the animal and the continued pull by the operator results in bringing the horses head back to normal.
The effect upon the horse appears to be soothing, and to actually assist in overcoming nervousness or fright, as undoubtedly the injury and consequent pain or shock occasioned by the jerking of the head of the horse, when tied, has frequently served to augment their fright or nervousness.
Of course, it is quite immaterial which end of the device may be attached toward the post, and which toward or to the head stall. The operation is the same in either case. ll have shown but a simple and preferred con struction embodying my invention, and I therefore do not purpose limiting the patent granted hereon otherwise than necessitated by the prior art.
I claim as my invention:
In a device of the class described, a casing, a spiral spring contained therein, a rod extending into said casing and at one end passing freely through one end of said casing, a head stop rigidly secured on the other end of said rod and adapted to receive one end of said spring thereagainst, guide rods secured within said casing and extending Patented Aug. as, rare.
through apertures in said head stop propscribed my name in the presence of two erly to space the spring and guide said head subscribing Witnesses. stop during its movement, and a stop at the head stop end of said spring and fixed to WALTER PELHAM' 5 said casing for engaging said head stop to Witnesses:
limit the expansion of said spring. CHARLES W. HILLS, J12,
In testimony whereof I have hereunto sub- Ln ROY D. KILEY.
Copies of this patent may be obtained for five cents each, by addressing the Commissioner of Patents, Washington, D. G.
Referenced by
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Comedian Tammy Pescatelli
Last Comic Standing's Tammy Pescatelli
Stand Up Live, Between S 1st and S Central (50 W. Jefferson St. Phoenix, AZ 85003)
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* Additional fees apply.
All offers for Comedian Tammy Pescatelli have expired.
The last date listed for Comedian Tammy Pescatelli was Sunday June 1, 2014 / 7:00pm.
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Many Women Unaware Of Heart Disease's Threat
Only one in five women are aware that heart disease is their greatest health threat.
New Haven Police Have "Person of Interest" In Yale Threat; Hope To Talk To Potential Witness
New Haven Police say they have a person of interest in last month's telephone threat to Yale University, and also are hoping to speak to a witness who may have more information in the case.
UConn Student Accused Of Threatening To Kill President
A UConn student has been charged with threatening to kill the president of the United States.
Conn. Elementary School Evacuated After Threat
An elementary school in Connecticut has been evacuated after what state police describe as a suspicious incident.
Multiple Hoax School Threats Strain Bridgeport Resources
Bridgeport police say eight bomb threats against city schools in the past week have put a strain on resources.
Security Experts Say Schools, Businesses Need Policies To Respond To Threats
With the deadly school shooting in Newtown, Conn., still fresh in their minds, FBI, state police and security experts offered advice Thursday to school administrators and private employers saying they will have to do more than a "lockdown" policy to prepare for and respond to an armed intruder.
Second Suspicious Powder Letter Sent To Governor
Authorities are investigating the second suspicious letter in a week sent to Gov. Dannel P. Malloy's office.
College Threat Hearing Delayed
BRIDGEPORT, Conn. (AP) _ A hearing to determine whether a woman charged with falsely threatening to carry out a suicidal mass shooting and bombing at Gateway Community College in New Haven should be released from […]
Hospital Lockdown Lifted
The Eastern Connecticut Health Network says Manchester Hospital was locked down Thursday.
All Clear Given After Threat At CCSU
A warning by Central Connecticut State University for people on campus to stay indoors after campus police received a threat has now been lifted.


text:
Little Pilgrims in God's World Set, 3 Volumes, Kindergarten
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Product Description
The accompanying activity book includes a variety of activities such as coloring, cutting, building, writing, map-work, memorization, and worksheets. A number of activities mentioned in the text are provided here. Accompanying the "Something else to do with Bible verse" activities, cut-out Bible verse flash cards are included; accompanying the "Something else to do" optional activities, cut-out vocabulary words and definitions for the mentioned Memory Game are provided.
The teacher's manual accompanies both the textbook and activity book. Organized by unit and lesson, lesson instructions (with notes on what the student is to read, what to discuss, and what pages to emphasize), textbook questions with answers, vocabulary words, and activities are listed. Kindergarten.
This kit includes:
This Product Contains The Following Items
|Little Pilgrims in God's World Textbook, Kindergarten
|Little Pilgrim in God's World K Teacher's Manual Kindergarten
|Little Pilgrims in God's World, Activity Book Kindergarten
Product Information
|Format: Paperback
Vendor: Christian Liberty Press
Publication Date: 2011
|Availability: In Stock
Series: Little Pilgrims
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12/19/2014Budgeting with M&M's?
12/19/2014Kansas Credit Unions Place First in State Industry Awards
12/16/2014Financial Counseling: Big Results in Little Time
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1/7/2015Disaster Management & Continuity Planning, Including Critical Vendors Webinar
Overview:Bankruptcy Update: Is It Over? The simple answer is NO! Members are still filing for bankruptcy at an alarming rate. While consumer filings in 2012 were actually lower than 2011 they were still as high as before bankruptcy reform! What will the rest of 2013 look like? Are you prepared? The session will examine the current state of consumer bankruptcy and how it continues to impact credit unions. It will focus on the nuts and bolts of an effective bankruptcy recovery and loss reduction program.
From the basics of bankruptcy terms to the most common landmines to maximizing recovery methods in collections, this program walks the credit union professional through the complicated world of bankruptcy in an easy to understand (and retain) format.
This session will cover the following:
About the Speaker: David A. Reed is an author, consultant and nationally recognized speaker. He received his undergraduate degree from Virginia Tech in 1986 and his Juris Doctorate from George Mason University School of Law in 1989. Formally, Mr. Reed was Vice President and General Counsel for Apple Federal Credit Union in Fairfax, Virginia. In his role as chief legal officer he established institutional legal policy, provided legal advice to the Credit Union concerning a variety of matters including the establishment and revision of Credit Union policies and procedures, organization compliance with federal regulations, contractual agreements, regulatory matters, and corporate governance. David has been selected to train NCUA Field Examination and Audit staff on Bankruptcy matters. He is an NCCO (NAFCU Certified Compliance Officer. Mr. Reed currently serves as editor of several manuals including Sheshunoff's Debt Collections Manual; and Sheshunoff's Practical Guide to Bankruptcy.
Educational Investment:Over $75 million - $159 per telephone connection$7-$75 million - $139 per telephone connectionUnder $7 million - $79 per telephone connectionArchive:An audio archive is available at no additional charge and can be accessed for 60 days after the live session. Instructions on accessing the archive will be sent with your connecting instructions and confirmation. Cancellation Policy:Sorry, no cancellations are allowed after connecting instructions and handout materials have been sent to registrants. Substitutions are welcomed and encouraged.


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Daughtry and 3 Doors Down Live at Jones Beach
* Additional fees apply.
The last date listed for Daughtry and 3 Doors Down was Wednesday July 17, 2013 / 7:00pm.
Most Popular Music Event Nearby
Bill Frisell's When You Wish Upon A Star at Lincoln Center
- Full Price:
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Listening to great music from classic films and TV shows has a tremendous power to evoke strong e...Learn More
Venue Details
The weather was overcast, damp and windy. I wore Sneakers, jeans and a sweater.Lionel Richie: All the Hits All Night Long dress • Jun 26 2014 star this tip starred
The weather was cool since the venue is on the water.. I wore regular top but you can bring a sweater or a wrap with you..Lionel Richie: All the Hits All Night Long dress • Jun 26 2014 star this tip starred
Reviews & Ratings
Featured review from Goldstar Member
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Daughtry and 3 Doors Down was an AMAZING concert!! We had the best time!! Both bands put on excellent performances!! They are so talented and know how to entertain!!
I especially like how they were so grateful to the crowd for our support of their music. I highly recommend both bands! Rock on!!!
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Really good seats and a really good show. Had a blast!
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Although I am familiar with Daughtry from AI and like his sound, I generally do not follow or purchase this genre of music. I also never heard of 3 Doors Down before I heard them perform last night. My eyes have been opened and now I am...continued
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Great concert !!
Quotes & Highlights
Watch videos and learn more about the band at Daughtry's official website.
Listen to music from 3 Doors Down at their official website.


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books by Winsor McCay
Forgotten Fantasy - Sunday Comics, 1900-1915: Visions from Lyonel Feininger, Winsor McCay and Many More ...
Sunday Press (CA)
, 2011
First in a new Anthology series from Sunday Press, acclaimed publisher full-size comic strip volumes. of Presented here in the original size and colors are the complete comics of Lyonel Feininger:The Kin-der-Kids and Wee Willie Winkie's World; along with the complete adventures of:The Explorigator by Henry Grant Dart, Nibsy the Newsboy by George McManus, and Naughty Pete by Charles Forbell Plus, color Dream of the Rarebit Fiend and Jungle Imp ...
Little Nemo in Slumberland: So Many Splendid Sundays!
Winsor McCay
Sunday Press Books
, 2005
"Likely the most spectacular book about comics ever" (LA TIMES) "....the finest." (TIME). The first edition of this book sold out in the first three months and is now out of print. The improved second printing is available NOW. Celebrate the 100th birthday of Winsor McCay's masterpiece with this FULL ORIGNAL SIZE, 120-page hardbound volume. It features Nemo's best from 1905-1910, all printed in the actual newspaper-page size, 16 x 21 inches. It ...
The Complete Little Nemo in Slumberland, Volume II: 1907-1908 (Complete Little Nemo)
Winsor McCay
Fantagraphics Books/Titan Books
, 1989
Little Nemo In Slumberland Vol.2 Hardback
Little Nemo in Slumberland Vol 2: Many More Splendid Sundays!
Winsor McCay
Sunday Press Books
, 2008
In 2005, the publication of Little Nemo in Slumberland: So Many Splendid Sundays, the oversized deluxe reprint edition, marked the centennial of Winsor McCay's supreme graphic achievement. That book astounded the world of comics and art, becoming the most highly praised book of its kind. This new collection presents more of those famed Sunday newspaper pages -- a "best of" collection from 1906 to 1924, with examples from all three incarnations ...
The Best of Little Nemo in Slumber Land
Winsor McCay,
Richard Marschall
Stewart Tabori & Chang
, 1997
Considered by many critics and artists to be the greatest comic strip of all time, Little Nemo in Slumbe rland was cherished in its day and honoured through the year s. This selection includes reproductions of more than 150 of McCay''s finest strips. '
Dreams of the Rarebit Fiend (Dover Humor)
Winsor McCay
Dover Publications
, 1973
From the creator of Little Nemo comes this pioneering cartoon strip, a world of dreams and nightmares, fraught with episodes of wish fulfillments and exaggerations in size and perspective. This facsimile of the rare 1905 first edition recaptures Winsor McCay's imaginative brilliance and his influence on latter-day animation with 60 cartoon sequences.
The Complete Little Nemo in Slumberland Vol. 1: 1905-1907
Winsor McCay
Fantagraphics Books
, 1998
A collection of Little Nemo's fantasy adventures, reprinted from the vintage comic strip.
Little Nemo: 1905-1914 (Evergreen)
Winsor McCay
, 2000
A reproduction of some of the "Little Nemo" comic strip from the early 20th century. This volume reflects the distinctive art-nouveau style of the original drawings and follows Little Nemo as he journeys nightly into the world of dreams.
Little Nemo In Slumberland 1906-1907 [Comic Anthology]
Winsor McCay
CreateSpace Independent Publishing Platform
, 2009
This is a special edition full-color reprint anthology of "Little Nemo In Slumberland" by Winsor McCay which includes Sunday strips from 1906-1907. Travel with Nemo as he goes on all his surreal escapades.
Dinomania: The Lost Art of Winsor McCay, The Secret Origins of King Kong, and the Urge to Destroy New York
Winsor McCay,
Ulrich Merkl
, 2015
This is a deluxe, oversize collection of Winsor McCay's ( Little Nemo) "lost" comic strip. Winsor McCay, the creator of Little Nemo in Slumberland , is internationally renowned as a pioneer in comics and animation. But author Ulrich Merkl's dedicated sleuthing has unearthed a never-published strip by McCay that was lost following the artist's untimely death. Titled simply Dino , it opens a surprising new window into McCay's life ...
Little Nemo In Slumberland HC Volume 1 Limited Edition
Winsor McCay
Checker Book Publishing Group
, 2007
Included here is every known episode from October 13th, 1905, the very frist, until August 15, 1909, never before published in complete collected form. in addition, another first: All forty-three episodes of McCay's first color Sunday feature, Tales of the Jungle Imps, As published in the Cincinnati Enquirer in 1903. Bonus promotional material includes playbills, posters, Little Nemo merchandise and more.
Dream Of The Rarebit Fiend: The Saturdays
Winsor McCay
Checker Book Publishing Group
, 2006
So popular, advance sales sold out our first print run before it even went to press, this oversized edition collects Winsor McCay's Saturday Dream of the Rarebit Fiend strips from 1904-1911. Presented in the enlarged format for the first time and printed 98% of their original size. 190 cartoons in all.
Daydreams and Nightmares: The Fantastic Visions of WInsor McCay, 1898-1934
Winsor McCay
Fantagraphics Books
, 2005
Daydreams & Nightmares collects the rarest work from Little Nemo In Slumberland creator Winsor McCay's historic career. A fantasist of the first rank, McCay was a key pioneer in the histories of both comics and animation. He had a fascination with dreams that extended beyond his newspaper strip Little Nemo in Slumberland , and it was a fascination as compelling as that of Freud, Jung and Adler's, as proven in the pages of Daydreams & ...
Winsor McCay: Early Works, Vol. 2
Winsor McCay
Checker Book Publishing Group
, 2004
Inside lurks more Dream of the Rarebit Fiend and Little Sammy Sneeze, plus Centaurs, Hungry Henrietta and dozens of McCay's editorial illustrations. Another handsome, compact and affordable collection of the work of Winsor McCay, the cartoon genius behind Little Nemo in Slumberland.
Winsor McCay: The Editorial Works
Winsor McCay
Checker Book Publishing Group
, 2006
Checker collects a new portion of McCay's career in this oversize format collection of his editorial artwork. This edition focuses on editorials that appeared from 1913-1917 as the United States saw an escalation of violence in Europe as a build up to World War I.
Daydreams and Nightmares
Winsor McCay
Fantagraphics Books
, 1988
by Windsor McCay A fantasist of the first rank, McCay was a key pioneer in the histories of both comics and animation. He had a fascination with dreams that extended beyond his newspaper strip Little Nemo In Slumberland, and it was a fascination as compelling as that of Freud, Jung and Adler's, as proven in the pages of Daydreams & Nightmares. McCay's dream-inspired strips, illustrations and cartoons feature rarebit-induced nightmares, playful ...
Little Nemo in Slumberland 1908-1909 [Full Color]
Winsor McCay
CreateSpace Independent Publishing Platform
, 2009
Little Nemo in Slumberland 1908-1909 [Full Color] contains all the Sunday strips of America's favorite little oneironaut (dream traveler) from 1908 and 1909 in full color. Follow Nemo in his fantastic adventures. This is the second volume, the first being 1906-1907.
Winsor McCay: Early Works, Vol. 3
Winsor McCay
Checker Book Publishing Group
, 2004
More Dream of the Rarebit Fiend (1907 strips), Little Sammy Sneeze, A Pilgrim's Progress (1907 Strips) and dozens of McCay's editorial illustrations from his New York period. Just a slice of the genius of McCay, who has been credited with over a million drawings in his lifetime.
Winsor McCay: Early Works, Vol. 1 (Early Works)
Winsor McCay
Checker Book Publishing Group
, 2003
A fully re-mastered collection of turn-of-the-century rarities from cartooning and animatino pioneer, Winsor McCay: Tales of the Jungle Imps, Little Sammy Sneeze, Dream of a Rarebit Fiend and Pilgrim's Progress. Best known for Little Nemo in Slumberland and the seminal animated feature Gertie the Dinosaur, McCay's artistic talent and whimsical humor are on full display here.
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Single Family/Site Built - Burnet, TX
Located at end of street for privacy and no traffic. Stone home on very large city lot with wonderful trees for a park like setting. Back and side yard are fenced. Homes interior has many wood ceilings plus rock work in living room ready for installation of wood burning stove. Large laundry room and beautiful kitchen with breakfast bar, island and granite counter tops. Very open living and kitchen area makes this a wonderful home for anyone including those that like to entertain. Nice size covered patio, and front porch. Ready for your touch on landscaping. Double garage with openers. Make your appointment today for personal viewing.
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It works great as keyboard and also as cover. It has a perfect fit. The only cons would be that in my case, the surface came a little bend (it could be the shipping) and the metal around the buttons came a little bend also (but not too much) Read more
Connection goes flawless. Just turn on BT on TAB3 and the keyboard and within seconds you can use it. Long lasting battery. When you flip the TAB you can click it on the keuyboard (face down) You cannot adjust the angle of the TAB3. But view angle of the TAB3 is quit good, so that is ok. When you click ... Read more
A good Bluetooth keyboard which works perfectly with the Samsung Galaxy Tab / Tab 2 10.1", other android devices and even with computers. It is really easy to connect it to any device. The Samsung Galaxy Tab. The keyboard can be used as a protective case for the back of the tablet, thus it is easy ... Read more
the keyboard was very easy to use, the manual was there and was explain step by step what you need to do. keyboard works very well and if you use it as case it looks like a laptop If you have your tablet on azerty keyboard you have to change to qwerty keyboard if you want to fully use it. do you want ... Read more


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Home » Local VoicesThe article requested cannot be found! Please refresh your browser or go back. (UL,20130419,LOCALVOICES,130418928,AR).
- School district to receive millions withheld by state - 2
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Small Salem school's students sliding into 'FIRST'READER COMMENTS: 0
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Instead of a ticket, he got $100 from policeREADER COMMENTS: 0
Details of Reams inquiry released
Details of Reams inquiry released
DWI License Revocations
DWI License Revocations
A working port: For a working state
A working port: For a working state
Details of Reams inquiry released
Details of Reams inquiry released
Pressuring FairPoint: Dems take a safe stand
Pressuring FairPoint: Dems take a safe stand
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2667 results for "larry fitzgerald"
Larry Fitzgerald #11 WR
REC YDS TD AVG LONG 57 722 2 12.7 80 FANTASY OWN(WK+/-) AVG DRAFT 73.2(-6.3) 41.2Update: Fitzgerald (knee) is probable for Sunday's game against Seattle. (Dec 19) Next Game: Seahawks at Cardinals Sunday 12/21 8:30 PM ET NBC
Mike & Mike on ESPN Radio: Show Preview December 16, 2014
Greeny and Golic welcome ESPN NFL analyst Herm Edwards (7:30 a.m. ET), ESPN NFL analyst Cris Carter (8:00), Cardinals WR Larry Fitzgerald (8:10) and Ravens WR Steve Smith (9:10) to the show on Tuesday. Get in touch with Mike & Mike by emailing (mikea...Blog | Conversation | December 15, 2014
Cardinals' offensive snaps: Week 15Josh Weinfuss
TEMPE, Ariz. -- A look at the Arizona Cardinals' offensive snap counts from Thursday's 12-6 win over the St. Louis Rams at the Edward Jones Dome. WIDE RECEIVERS Michael Floyd: 59 of 68 Larry Fitzgerald: 56 of 68 John Brown: 42 of 68 J...Blog | December 15, 2014
Larry Fitzgerald, Troy Polamalu among finalists for sportsmanship...
Wide receivers Larry Fitzgerald and Calvin Johnson are among eight finalists for the NFL's new Sportsmanship Award.Story | Conversation | December 15, 2014
Audio results for "larry fitzgerald"
Larry Fitzgerald, CardinalsDecember 16, 2014
Mike & Mike 12/16 - Hour 3December 16, 2014
Fantasy Focus Football - Week 7 RecapOctober 20, 2014
Michael Floyd, CardinalsAugust 12, 2014
Drew Stanton a better QB with Larry Fitzgerald on the fieldJosh Weinfuss
TEMPE, Ariz. - Larry Fitzgerald will downplay it until it snows in Arizona, but him being on the field has been the difference between winning and losing for the Arizona Cardinals. And he's helped Drew Stanton looked like a bona fide starting quar...Blog | December 11, 2014
Video results for "larry fitzgerald"
Hope For Ryan Lindley As Cardinals QB?December 16, 2014
Larry Fitzgerald Has MCL SprainNovember 17, 2014
Game Balls: Philadelphia at ArizonaOctober 26, 2014
Don't Ever Give Up: Larry FitzgeraldJuly 09, 2014
- 01:17
Cousin Sal's Week 15 Prop Bets!Cousin Sal Iacono
Let's get through this weekly charade quickly. I have a ton of empty gift cards to "buy." On to the Thursday-night game props: Larry Fitzgerald under 55.5 yards receiving The Cardinals' premier wide receiv...Blog | December 11, 2014
Fantasy: Thursday night injury updateStephania Bell
This is not the same St. Louis Rams team that the Arizona Cardinals faced in Week 10. In that contest, the Cardinals won handily (31-14), and in doing so improved to 9-1 and maintained their spot atop the NFC West. Since then, each team has moved...Blog | December 11, 2014
Larry Fitzgerald sees San Antonio Spurs in CardinalsJosh Weinfuss
TEMPE, Ariz. -- Through 13 games this season, the Arizona Cardinals have shown some flash a time or two. But in reality, the Cards haven't "wowed" anyone with showy performances that are highlight worthy. Sure, there's a play here and there, but A...Blog | December 10, 2014
NFL to recognize sportsmanship with new award voted on by players...
The NFL has created a sportsmanship award to be voted on by league players.Story | Conversation | December 09, 2014
Cardinals' offensive snaps: Week 14Josh Weinfuss
TEMPE, Ariz. -- A look at the Arizona Cardinals' offense snap counts from Sunday's 17-14 win over the Kansas City Chiefs at University of Phoenix Stadium. WIDE RECEIVERS Michael Floyd: 62 of 69 Larry Fitzgerald: 58 of 69 John Brown: 45 of 69 ...Blog | December 09, 2014
Andre Ellington of Arizona Cardinals out with hip injury vs. Kans...Josh Weinfuss
The Arizona Cardinals will be without starting running back Andre Ellington against the Kansas City Chiefs on Sunday.Story | Conversation | December 05, 2014
Prediction: Cardinals continue to slideJosh Weinfuss
There are few reasons to believe Arizona can figure out its offensive issues and correct them for Sunday's game. The Cardinals are averaging a league-low 3.08 yards per carry - a number that drops to 1.79 when Larry Fitzgerald isn't on the field, ...Blog | December 05, 2014
Larry Fitzgerald learned to stay quiet on sideline when not playi...Josh Weinfuss
TEMPE, Ariz. -- All it took was a former teammate who wasn't playing to talk to Arizona Cardinals WR Larry Fitzgerald during a game early in his career to teach Fitzgerald not to be that guy. While he was out for Arizona's past two games, Fitzgera...Blog | December 05, 2014
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UFC Fight NightDecember 13, 2014
Arizona Cardinals v St Louis RamsDecember 11, 2014
Kansas City Chiefs v Arizona CardinalsDecember 07, 2014
Kansas City Chiefs v Arizona CardinalsDecember 07, 2014
Larry Fitzgerald says it's 'highly likely' he'll play Sunday, and...Josh Weinfuss
TEMPE, Ariz. - For the second straight Thursday, Arizona Cardinals wide receiver Larry Fitzgerald said it's "highly likely" he'll play on Sunday. This time, he might actually be right. Fitzgerald has been limited in practice the last two days b...Blog | December 04, 2014
Cards' offense to get boost with Larry Fitzgerald's returnJosh Weinfuss
TEMPE, Ariz. -- There may be nobody in the Arizona Cardinals' locker room more excited to see wide receiver Larry Fitzgerald back at practice Wednesday than Drew Stanton. For the past two games (both losses), the quarterback has struggled to ignit...Blog | December 04, 2014
2014 rankings update: Fantasy playoff helpEric Karabell
Welcome to December and the fantasy football playoffs, and since there's no more trading and only a few more weeks left, we've come to the end of the road for the weekly blog entry that has been the end-of-season rankings. Hope you've enjoyed it as m...Blog | December 02, 2014
Larry Fitzgerald inactive for second-straight gameJosh Weinfuss
ATLANTA -- For the first time since 2006, Arizona Cardinals wide receiver Larry Fitzgerald will miss two straight games in a season. Fitzgerald was ruled inactive for Sunday's game in Atlanta as he continues to recover from a sprained MCL in his l...Blog | November 30, 2014


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"Here there be dragons" is what the map ends used to say. After you learn to use the end component successfully your projects will be dragon-free.
Dig in to create a Decision Only project to work with the End component. Keep a weather eye.
Prerequisites: None
Objective: To learn to work with the End Component.
Estimated time to complete: 15-20 minutes
Step 1: Create a new Decision Only project.
Step 2: Set the Input and Output Data as shown below.
Step 3: Drag and drop an AddValues component and connect them as shown below. Right click the End component and select Edit Component.
Step 4: Click the selector button next to the Mapping field.
Step 5: Select the Value from data radio button in the End Component Mapping window and click on the selector button.
Step 6: Click on 'ret' as shown below:
Step 7: Finished!


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Center on Children & Families
Recent Publications
Legal Representation of Dependent Children
The Shackling of Juvenile Offenders: The Debate in Juvenile Justice Policy
Visit the Juvenile Justice Project Web site
Seeds of Violence Conference
November 14, 2014 was a huge success and spawned the creation of a new local organization aimed at creating a trauma informed community.
Find out more at Peace4Gainesville.org
2014-15 Weyrauch Distinguished Lecture in Family Law
Carol Sanger Professor of Law at Columbia Law School
March 18, 2015
Room 180 at the College of Law
Abortion/Privacy Abortion/Secrecy: What's the Difference and Why Does it Matter?
Open to the Public
Southern Poverty Law Center Report: Corporal Punishment Ineffective, Should be Eliminated from Florida Schools
The report was written by University of Florida researchers Joseph Calvin Gagnon, Ph.D., associate professor in the Department of Special Education; Brianna L. Kennedy-Lewis, Ph.D., assistant professor in the School of Teaching and Learning; and Sungur Gurel, M.A., Afilliated faculty of the Center on Children & Families
CCF File Briefs with United States Supreme Court
Adoptive Couple v. Baby Girl
The Center on Children and Families has filed an Amicus Brief with the United States Supreme Court. The case of Adoptive Couple v. Baby Girl, a minor under the age of fourteen years, Birth Father, and the Cherokee Nation, No. 12-399, is set to decide two issues: whether a non-custodial parent can invoke ICWA to block an adoption voluntarily and lawfully initiated by a non-Indian parent under state law; and whether ICWA defines "parent" in 25 U.S.C. § 1903(9) to include an unwed biological father who has not complied with state law rules to attain legal status as a parent.
Click here to download the brief.
Emory Child Rights Project
"LGBTQ YOUTH AND YOUNG ADULT SURVEY: A Joint Project on Marriage Equality of the University of Florida Center on Children and Families and the Emory Child Rights Project" by Kathryn Brightbill, Brian W. Kaufman, Margaret Riley, and Nick Vargo
Hollingsworth v. Perry and United States v. Windsor
The mission of the Center on Children and Families is to promote the highest quality of advocacy, teaching and scholarship in the areas of child & family law and policy. Read More »


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Vicky and Melanie
Walter Franklin DANSBY was elder brother of my Grandfather John Wiley DANSBY. My records are incomplete ie missing information identifying the names for Will Ts spouse and children. Any help in this matter is appreciated.
James Madison Daniel
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MTGCast #136 - Nicol Bolas, Path to Exile and more Conflux Rumors!
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Conflux Scuttlebutt
NOTE: End of spoilers is at 21:22
A bunch of awesome spoilers this week. First is Path of Exile, a new Swords to Plowshares variant. We also three new Scepters, Scepters of Dominance / Insight / Fugue with many players especially excited about the Scepter of Dominance. We also have a bunch of info about the upcoming Nicol Bolas planeswalker card with the ability to destroy non-creature permanents, control creatures and a last ability "better than Cruel Ultimatum"! Who doesn't love some tasty functional reprints, we have the new Gaea's Might in the form of Might of Alara and the reprint of the 2/2 dual color with protection from enemy color last seen in Invasion (e.g. Shivan Zombie). And lastly, a crazy rumor of a card named Blood Tyrant that supposedly gets 5 +1/+1 counters when a player loses a game. Time to get those Shahrazads!
NOTE: End of spoilers is at 21:22
User Corner
Tons of great questions, decks lists, discussion of Standard Elfball sideboards and some Extended talk!
MTGCast News
We welcome a new show on the network, Mr. Suitcase! We also highly recommend listening to the latest Magic School Bus episode, it is exceptionally well done and worth a listen. We also officially announce you can get your hooks on the Ah-hoy! custom pirate-themed MTG set. Check out the visual spoiler and download the Magic Set Editor file!
Emails, Comments and COMMENT CONTEST!
The winner this week of the deck challenge is ... mrme355!
The winner this week of the comment challenge is ... Dark_drac0!
This is a new weekly contest where I announce a deck challenge and ask for feedback on the podcast, you post a response (or story) on the MTGSalvation, Star City Games or TCGplayer forums. Then, I will give out two prizes each week, one to a great deck and one to comments / suggestions!
This week's deck challenge card is: Evil Presents (latest Holiday promo)!
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Invited Review
You have free access to this content
CAR T cells: driving the road from the laboratory to the clinic
Article first published online: 13 DEC 2013
DOI: 10.1111/imr.12126
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Immunological Reviews
Special Issue: Adoptive Immunotherapy for Cancer
Volume 257, Issue 1, pages 91–106, January 2014
Additional Information
How to Cite
Cheadle, E. J., Gornall, H., Baldan, V., Hanson, V., Hawkins, R. E. and Gilham, D. E. (2014), CAR T cells: driving the road from the laboratory to the clinic. Immunological Reviews, 257: 91–106. doi: 10.1111/imr.12126
Publication History
- Issue published online: 13 DEC 2013
- Article first published online: 13 DEC 2013
Funded by
- Kay Kendall Leukaemia Fund
- Cancer Research UK
- the Technology Strategy Board
- Cellular Therapeutics Ltd
- 1
- 2Antibodies in oncology. N Biotechnol 2011;28:518–529., , .
- 3Emerging immunotherapies for renal cell carcinoma. Ann Oncol 2012;23(Suppl):viii35–vii40..
- 4IFN-alpha in the treatment of melanoma. J Immunol 2012;189:3789–3793., , .
- 5Donor lymphocyte infusions for relapse after allogeneic transplantation: when, if and for whom? Blood Rev 2013;27:55–62., .
- 6Role of donor lymphocyte infusions in relapsed hematological malignancies after stem cell transplantation revisited. Cancer Treat Rev 2010;36:528–538., .
- 7Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J Immunother 2003;26:332–342., , , , .
- 8Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol 2005;23:2346–2357., et al.
- 9Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin Cancer Res 2011;17:4550–4557., et al.
- 10Adoptive transfer of tumor infiltrating lymphocytes in metastatic melanoma patients: intent-to-treat analysis and efficacy after failure to prior immunotherapies. Clin Cancer Res 2013;19:4792–4800., et al.
- 11
- 12CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 2013;5:177ra138., et al.
- 13T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 2011;3:95ra73., et al.
- 14B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 2012;119:2709–2720., et al.
- 15Molecular lesions in B-cell lymphoproliferative disorders: recent contributions from studies utilizing high-throughput sequencing techniques. Leuk Lymphoma 2013. [Epub ahead of print]., , .
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- 41T cell activation by antibody-like immunoreceptors: the position of the binding epitope within the target molecule determines the efficiency of activation of redirected T cells. J Immunol 2007;178:4650–4657., , , , , .
- 42Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells. Clin Cancer Res 2013;19:3153–3164., et al.
- 43Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane. J Immunol 2008;180:7028–7038., et al.
- 44IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression. Cancer Res 2011;71:5697–5706., , , .
- 45Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning. Blood 2012;119:4133–4141., et al.
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- 47CD34 splice variant: an attractive marker for selection of gene-modified cells. Mol Ther 2000;1:448–456., et al.
- 48CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activation. Mol Ther 2011;19:760–767., et al.
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- 58Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies. Mol Ther 2008;16:580–589., et al.
- 59piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies. Hum Gene Ther 2010;21:427–437., et al.
- 60PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor. Mol Ther 2011;19:2133–2143., et al.
- 61Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies. Hum Gene Ther 2012;23:444–450., et al.
- 62Transfer of mRNA encoding recombinant immunoreceptors reprograms CD4+ and CD8+ T cells for use in the adoptive immunotherapy of cancer. Gene Ther 2009;16:596–604., et al.
- 63
- 64Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J Clin Oncol 2008;26:5233–5239., et al.
- 65Modulating the differentiation status of ex vivo-cultured anti-tumor T cells using cytokine cocktails. Cancer Immunol Immunother 2012;62:727–736., et al.
- 66
- 67CD8+ enriched "young" tumor infiltrating lymphocytes can mediate regression of metastatic melanoma. Clin Cancer Res 2010;16:6122–6131., et al.
- 68Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells. Nat Med 2009;15:808–813., et al.
- 69Th17 cells are long lived and retain a stem cell-like molecular signature. Immunity 2011;35:972–985., et al.
- 70Cancer vaccines and T cell therapy. Biol Blood Marrow Transplant 2013;19:S97–S101., et al.
- 71Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15. Nat Med 2003;9:279–286., et al.
- 72T-cell clones can be rendered specific for CD19: toward the selective augmentation of the graft-versus-B-lineage leukemia effect. Blood 2003;101:1637–1644., et al.
- 73CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells. Cancer Res 2006;66:10995–11004., et al.
- 74Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo. Mol Ther 2009;17:1453–1464., et al.
- 75Cytotoxic T cells transduced with chimeric anti-CD19 receptors prevent engraftment of primary lymphoblastic leukemia in vivo. Leukemia 2010;24:1080–1084., et al.
- 76
- 77Natural expression of the CD19 antigen impacts the long-term engraftment but not antitumor activity of CD19-specific engineered T cells. J Immunol 2010;184:1885–1896., , , , , .
- 78Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice. Blood 2009;114:5454–5463., et al.
- 79Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts. Clin Cancer Res 2007;13:5426–5435., et al.
- 80Addition of the CD28 signaling domain to chimeric T-cell receptors enhances chimeric T-cell resistance to T regulatory cells. Leukemia 2006;20:1819–1828., , , , , .
- 814-1BB and CD28 signaling plays a synergistic role in redirecting umbilical cord blood T cells against B-cell malignancies. Hum Gene Ther 2010;21:75–86., et al.
- 82Ligation of the CD2 co-stimulatory receptor enhances IL-2 production from first-generation chimeric antigen receptor T cells. Gene Ther 2012;19:1114–1120., , , , , .
- 83A chimeric receptor that selectively targets membrane-bound carcinoembryonic antigen (mCEA) in the presence of soluble CEA. Gene Ther 1999;6:300–304., et al.
- 84Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells. Blood 2010;116:3875–3886., , , , .
- 85Novel cellular therapies for leukemia: CAR-modified T cells targeted to the CD19 antigen. Hematology Am Soc Hematol Educ Program 2012;2012:143–151., .
- 86Targeted immunotherapy of cancer with CAR T cells: achievements and challenges. Cancer Immunol Immunother 2012;61:953–962., , , .
- 87Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans. Biol Blood Marrow Transplant 2010;16:1245–1256., et al.
- 88Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 2011;118:4817–4828., et al.
- 89B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 2012;119:2709–2720., et al.
- 90CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 2013;5:177ra138., et al.
- 91CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest 2011;121:1822–1826., et al.
- 92T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 2011;3:95ra73., et al.
- 93Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med 2013;368:1509–1518., et al.
- 94Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans. Biol Blood Marrow Transplant 2010;16:1245–1256., et al.
- 95CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest 2011;121:1822–1826., et al.
- 96Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med 2013;368:1509–1518., et al.
- 97CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results. Blood 2012;119:3940–3950., et al.
- 98CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results. Blood 2012;119:3940–3950., et al.
- 99Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in metastatic melanoma patients. Clin Cancer Res 2010;16:2646–2655., et al.
- 100High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J Sci Am 2000;6(Suppl 1):S11–S14., , , .
- 101High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol 1999;17:2105–2116., et al.
- 102Current treatment considerations in metastatic renal cell carcinoma. Curr Treat Options Oncol 2012;13:212–229., .
- 103Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity 2013;38:13–25., , .
- 104The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor. Blood 2010;116:4532–4541., et al.
- 105In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor. Blood 2011;117:4736–4745., et al.
- 106CD19 CAR-targeted T cells induce long-term remission and B cell aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia. PLoS ONE 2013;8:e61338., , , .
- 107Treatment of chronic lymphocytic leukemia with genetically targeted autologous T cells: case report of an unforeseen adverse event in a phase I clinical trial. Mol Ther 2010;18:666–668., , , , .
- 108Natural expression of the CD19 antigen impacts the long-term engraftment but not antitumor activity of CD19-specific engineered T cells. J Immunol 2010;184:1885–1896., , , , , .
- 109CD19 CAR-targeted T cells induce long-term remission and B cell aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia. PLoS ONE 2013;8:e61338., , , .
- 110Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells. Blood 2010;116:3875–3886., , , , .
- 111A CD28 containing CAR plus t-cells targeting mouse CD19 causes both short and long-term toxicity when transferred into pre-conditioned mice. Hum Gene Ther 2009;20:1383–1384., et al.
- 112CAR-T cells and solid tumors: tuning T cells to challenge an inveterate foe. Trends Mol Med 2012;18:377–384., , , , .
- 113Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 2010;18:843–851., , , , , .
- 114Antigen-specific targeting of CD28-mediated T cell co-stimulation using chimeric single-chain antibody variable fragment-CD28 receptors. Eur J Immunol 1996;26:2304–2309., .
- 115Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells. Nat Biotechnol 2013;31:71–75., , , , .
- 116Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling. J Clin Immunol 2012;32:1059–1070., et al.
- 117Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity. Mol Ther 2013;21:904–912., et al.
- 118
- 119An inducible caspase 9 safety switch for T-cell therapy. Blood 2005;105:4247–4254., et al.
- 120A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells. Blood 2011;118:1255–1263., et al.
- 121A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer. Clin Cancer Res 2006;12:6106–6115., et al.
- 122Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. Blood 2011;118:6050–6056., et al.
- 123A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR. Blood 2012;119:5697–5705., et al.
- 124Orchestrating the orchestrators: chemokines in control of T cell traffic. Nat Immunol 2008;9:970–980., , .
- 125Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. Hum Gene Ther 2002;13:1971–1980., et al.
- 126T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model. Blood 2009;113:6392–6402., et al.
- 127Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J Immunother 2010;33:780–788., et al.
- 128Eotaxin-2 and colorectal cancer: a potential target for immune therapy. Clin Cancer Res 2007;13:5719–5728., et al.
- 129Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor. J Immunother 2008;31:500–505., et al.
- 130Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis. Blood 2005;105:4677–4684., et al.
- 131Retroviral transduction of human peripheral blood lymphocytes with Bcl-X(L) promotes in vitro lymphocyte survival in pro-apoptotic conditions. Gene Ther 2002;9:527–535., , , .
- 132Chimeric antigen receptors for T-cell based therapy. Methods Mol Biol 2012;907:645–666., et al.
- 133Development of a flow cytometric co-immunoprecipitation technique for the study of multiple protein-protein interactions and its application to T-cell receptor analysis. Cytometry A 2010;77:338–346., , , .
- 134The optimal antigen response of chimeric antigen receptors harboring the CD3zeta transmembrane domain is dependent upon incorporation of the receptor into the endogenous TCR/CD3 complex. J Immunol 2010;184:6938–6949., , , , , .
- 135
- 136Engineering T cell function using chimeric antigen receptors identified using a DNA library approach. PLoS ONE 2013;8:e63037., et al.
- 137Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer. Oncoimmunology 2013;2:e22691., , .


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Beautyfull ¡ :)
Thanks very much livedrive
Beautiful view!
LIKE 6 , Dear OLGA YAKOVENKO , i invite you to join the International Collaction BICYCLES FAHRRAEDER , with as many as you wish fotos !!!!!Panos from Hellas - Greece and Luxembourg !!!
well it is better tha this http://www.panoramio.com/photo/51823602
And the lifts work and there is no graffiti etc
We cannot all live in villas with gardens
Its beautiful :) I like so much
perfectas fotografias !!!muy lindas
good luck
Bello paisaje,voto y like,un saludo cordial.
Interessantes Foto, ich schaue es mir öfters an.
Very well composed picture Olga. LIKE 2.
Greetings, Erika
lovely composition!...best of...warm regards from Riyadh city


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It's 100% true! Jewish Americans are 100% loyal to israel. Why do you think they never report the bad things Jews do?
If selected for publication, it will appear as soon as possible on Haaretz.com.
A new opinion poll suggests that Israelis' approval of President Barak Obama is on the rise, Anti-Defamation League National Director Abraham Foxman said on Tuesday.


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Notre Dame v Cincinnati
Similar imagesView all
Eric Atkins of the Notre Dame Fighting Irish brings the ball upcourt... News Photo 159555458Ball,Basketball - Men's College,Cincinnati,Cincinnati Bearcats,Eric Atkins,Fifth Third Arena,Full Length,Head Coach,Match - Sport,Mike Brey,Notre Dame Fighting Irish,Ohio,Past,Sport,USA,Upcourt,VerticalPhotographer Joe RobbinsCollection: Getty Images Sport 2013 Joe RobbinsCINCINNATI, OH - JANUARY 7: Eric Atkins #0 of the Notre Dame Fighting Irish brings the ball upcourt past head coach Mike Brey during the game against the Cincinnati Bearcats at Fifth Third Arena on January 7, 2013 in Cincinnati, Ohio. Notre Dame won 66-60. (Photo by Joe Robbins/Getty Images)


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EarSonics EM32
"EarSonics has made its last flagship for the guigs, but the EM32 can without a doubt satisfy audiophile who are looking for the "neutrality" with a reinforcement in the sub and the highs. The main characteristic is the same as for the EM3pro/EM4/EM6 : musicality and body ! But here you have all in one, that's the improvement. 3 transducers, 3 ways, two bores, no one on the market is..." --Rollk2
EarSonics SM3 Universal Fit IEM
"Remember those essays you had to write in grade school? Well I do even if you don't. In honor of that memory, I am going to write: What does the EarSonics SM3 mean to me? Back in March I was going to order the EarSonics SM3 based off the few things I have read about them, even though it wasn't much. But then something stopped me. Could they really be that good, and the shipping cost was as..." --average_joe
Tralucent Audio 1Plus2
"*Please ignore the audio quality / comfort / design / isolation / value sliders for this review. As far as I can tell, they seem broken* This is a universal in-ear monitor with a two balanced armature drivers and a dynamic driver. This earphone costs $1250 IEM with a cable that costs about $800, or as a package together, about $1400. I'm part of an Australian listening tour for this..." --a_recording
EarSonics Velvet
EarSonics Velvet DESIGN To create the VELVET , we have carefully studied every detail of its design. It's result this modern and fluid design fully adapted to the ear anatomy. A sleeker look and a pleasant touchdown resulting of the noble material choice. The VELVET was born SOUND Balance and tone respect are the key words that best characterize the VELVET . We have taken great care...
EarSonics EM3-PRO
Top of the line custom IEMs made by earsonics.
Tralucent Audio Ref 1
"Tralucent Audio Reference 1 – With Comparisons I would first like to give a huge thanks to Head-Fi member, warrior1975 for loaning me his Ref. 1 and TWau cable for review. I was interested in hearing what the hub-bub was all about regarding the Ref. 1. I was interested further because most people who have heard it either love the..." --moedawg140
EarSonics SM64
"THE RATINGS: Highs: 4.5/5 Mids: 5/5 Lows: 4.5/5 (probably would be 5/5 with amping) Bass: 5/5 (swooshy style, though) Value: 5/5 Soundstaging: 5/5 This is all to say that the Earsonics SM64s are perhaps the best IEMs I have ever heard, and I was always a big IEM person. Let's be short about this: It absolutely slaughters the Shure SE530, SE535 line..." --Pepper
EarSonics SM1 Earphones
The SM1 simply offers the best technology with single transducer. A detailed and balanced sound. clear low-end, good mids and an incredible high range finesse. The best choice to taste the in-ears quality at lower costs Specifications: Sensitivity:109 dB/mW Frequency Response: 20 Hz -18 kHz Impedance: 10 ohms Driver: 1 HQ driver Included in the box wipes, tool, soft bag, proprietary silicon...
EarSonics SM3 v2 universal in-ear monitors
"http://www.earsonics.com/SM3%20engl.htm v2 page. Aside from the cable and new body, my impressions match what I had in my v1 review. http://www.head-fi.org/products/earsonics-sm3-universal-fit-iem/reviews/4422 Otherwise, these sound about the same as v1/the new ear-piece body shape is a lot more ergonomic(seems to be a bit smaller as well, but not as easy to get a good seal... At the same..." --svyr
EarSonics EM6 Custom IEM
The new in-ear monitors reference for live performance, sound-based on EM4 technology but adapted to live.The best professional tool for exigents musicians who wait for best audio quality. The spectral balance is rigorous and a musical as never achieved before in an in-ear. Deep and "clean" lows, a "Earsonics touch" medium and treble with incredible sharpness. The...


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What we saw was what we gotMarch 20,2014Taken By Storm 1938 is the detailed account of the hurricane that devastated much of New England in 1938. The
author, Lourdes B. Aviles, remembered growing up in Puerto Rico as a young girl extremely interested in hurricanes, which were quite frequent. Now, she is professor of meteorology at Plymouth State College in New Hampshire, a state that was particularly stricken by that particular storm.
The author says the word hurricane is derived from a Spanish word, huracán, which, in turn, was a phonetic spelling of a word the West Indian tribes had for the deity that brought terrible storms to their islands. Their word for that deity was Jurakan, which the author says is pronounced hoo-rah-kahn.
As you might guess from the authors professorship, her book is not only an account of that storms effects, but also of the condition of the official weather forecasting system in those years.
In the first place, the forecasting personnel were in the U.S. Department of Agriculture. It was only in later years that they were transferred to the Commerce Department. Information for farmers had been one of their principal tasks, but, by 1938, the airline industry had become very interested in what sort of weather their planes would be flying in. Instrument flying was in its infancy, and pilots had to operate a lot by sight alone.
There was no such thing as satellite observation, and weather conditions at sea had to come largely from what was reported from ships in any particular neighborhood.
While Weather Service headquarters were in Washington, where part of the Atlantic seaboard was monitored, there were subordinate offices in Jacksonville, Fla., and in Puerto Rico.
The general reader of this book would be advised not to shudder at the occasional scientific references that are of interest to meteorology students mostly. For instance, this footnote:
One hectopascal equals 100 pascals. A pascal is the international unit of pressure, equal to a Newton per square meter or a kilogram per meter second squared.
In 1938, when the Weather Service spoke of a tropical storm, it often meant a storm that had originated in the tropics. In mid-September 1938, Jacksonville reported such a storm out in the Atlantic headed in a northwest direction, which meant it was headed toward Florida. People in that state had experience with hurricanes and began to think of boarding up their facilities. But much to their relief, it swung north. The author says it achieved a northward speed of 50 mph, which is pretty fast for such a disturbance.
The Washington office thought the storm would follow the customary path of veering eastward before landfall. But during that season, the Bermuda high to the east was especially strong, and a special low-pressure system over the Alleghenies tended to attract the storm in a northward direction. So on Sept. 21, it slammed into Long Island, crossed Long Island Sound and punched into Connecticut, continuing through central Massachusetts and into New Hampshire and Vermont.
The author makes clear that one reason for the extensive flooding was not so much because of the rain the hurricane brought as that the ground had already been soaked by a summer of extensive rainfall. She likens it to what happened more recently with Tropical Storm Irene.
Trees were flattened, including several hundred thousand maples. There was an extensive forest of white pines west of Keene, N.H., that was completely flattened.
My family had a farm in Londonderry in the northwest corner of Windham County. Because that area was on the west side of the counter-clockwise hurricane motion, the wind came out of the northeast. It blew hard with occasional stronger gusts, one of which blew over an apple tree in our yard, moved our woodshed back 4 feet and left a trail of downed timber in the woods in back of the house.
While working outside to save the barn and other buildings, my mother exclaimed that she could taste sea salt in the rain. And when things cleared in a day or two, the east windows of the Vermont State House in Montpelier were found to be plastered with sea salt.
Of course, power and phone service were completely out. Our farm was heated by two woodstoves, one in the kitchen on which my mother also cooked and the other in the living room. So, in that respect, we were better off than many, but it was a long time before electricity and phone service came back.
The Weather Service took criticism afterward for not warning more strongly about the storm. The author of this book does a good job of explaining why it wasnt carelessness that was at fault, but lack of equipment to assess developments.
Kendall Wild is a retired editor of the Herald.MORE IN CommentaryThe sit-ins, die-ins, marches and other demonstrations sparked by the tragic deaths of Michael... Full StoryMaybe Im just projecting, but Christmas seemed unusually subdued this year. Full StoryMore than we may realize, the world has been riding a lucky streak since the global financial... Full Story
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Vieirão pegmatite, Barra do Salinas, Coronel Murta, Jequitinhonha valley, Minas Gerais, BrazilThis page is currently not sponsored. Click here to sponsor this page.
Mineral List
| Lepidolite
| Spodumene
| 'Tourmaline'
3 entries listed. 2 valid minerals.
The above list contains all mineral locality references listed on mindat.org. This does not claim to be a complete list. If you know of more minerals from this site, please register so you can add to our database. This locality information is for reference purposes only. You should never attempt to visit any sites listed in mindat.org without first ensuring that you have the permission of the land and/or mineral rights holders for access and that you are aware of all safety precautions necessary.
Bastos, F.M. (2002): Famous Mineral Localities: The Barra de Salinas Pegmatites, Minas Gerais, Brazil. Mineralogical Record 33: 209-216
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