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Wilkinson placed sixth overall in the 400 meters at the MWC Indoor Championships ... Came back during the outdoor season to collect third-place honors at the TCU Invitational and Horned Frog Invitational in the 400 ... Also competed in the 200 meters, while gaining valuable experience on the Flyin' Frogs sprint medley and 4x400 ... Helped the sprint medley relay clock an NCAA regional qualifying time of 3:33.01 seconds at the Texas Relays to finish in third-place.
Gained valuable experience during the indoor season in both the sprints and 4x400 relay ... posted a personal-best of 24.55 in the 200 at the UTA Open ... Finished fifth overall in the prelims of the 200 meters at the MWC outdoor Championships ... Also ran the 400 meters at the John Jacobs Invitational and UTA Open ... Was a member of the conference champion 4x400 relay as well as the Midwest Regional squad that placed fourth overall in Lincoln with a seasonal-best time of 3:36.98 ... Earned all-conference and all-region honors as a member of the 4x400 unit ... Helped the squad place first overall at the Penn Relays.
Broken Arrow High School
Wilkinson finished off her high school career holding individual school records in both the 100 (11.61) meters and 200 (24.10) meters ... She was the state champion in the 100 meters her sophomore and junior seasons at Broken Arrow ... Also collected state championship honors in the 200 meters her junior season ... Wilkinson excelled in basketball at Broken Arrow, earning three letters.


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Town Council: Bill McKernan
"You know how you just get attracted to a place?" asks Town Council candidate Bill McKernan (R). For him and his wife Rheba, that was Block Island. "We made so many friends here… things just fell into place."
Despite being fairly new to the Block Island community, having resided here for seven years, McKernan's island dedication is deep. He is a long-time visitor and is involved in many community-oriented activities.
In addition to serving on the Library Board and as Adjutant at Legion Post 36, he's a been regular presence at almost every Town Council meeting the past few months, where he can be found in the audience, sitting, learning and sometimes participating, all the way until the end, even as the meetings last late into the evenings.
"My fresh perspective may help on the council," he suggested, and adds that he's willing to learn from other's views and wants to encourage public input.
He even brings up three basic points taken from his role as audience member that he would like to implement if elected: visual aids during meetings ("I see people in the audience trying to follow along"), increased use of the microphone, and having everyone introduce themselves before speaking.
Deepwater, energy costs and
But beyond the basics, McKernan has many hopes and plans if chosen to serve as councilman. He says one of the biggest priorities for him is Deepwater Wind and making sure a cable to the mainland, along with Fiber Optic technology, happens whether or not Deepwater does.
"We can't continue to pay fifty cents a kilowatt hour," he said. "Can you imagine a family paying that cost for energy?"
He further notes that even if Deepwater does happen, the town needs to closely examine Block Island Power Company rates — and fully understand the relationship between the National Grid, BIPCo and Deepwater.
And McKernan's past experience working for AT&T will provide valuable knowledge as the time of the cable's installation grows near — he can delve deep into explaining the details of fiber-optic technology. He thinks the town must more aggressively lobby Verizon for better Internet quality. And, if the Deepwater cable comes in, they must reach out to other vendors, too.
"At AT&T… I used to handle accounts similar to [Block Island]. They all had fiber-optics," he said. "They all have departments that deal with state and local… we have to go to them and say 'What's your plan?' for us."
"Everyone's using it" on the mainland, he added. "It's important for the kids in school, to make more bandwidth for education and distance learning, and the medical center even needs it."
He notes that there are grants available to try to help rural areas get high-speed Internet, but "Rhode Island is not part of that. The representatives in Providence forget that we need that here."
State representation, town budget and maintenance
McKernan — who as chair of the Block Island Republicans coordinated bringing over several Republican state candidates this election season — hopes to be able to vamp up Block Island's presence upstate and "get the representatives closer to us."
McKernan's first taste of politics was back when he was a kid, as a native New Yorker in high school where he helped out with a friend's campaign.
"Every party can have good ideas, and you've got to work well with people," he said.
And he knows that Block Island has some really special people, such as those he works with on the library board, the friends and neighbors he's met over the years and the great experiences many have had here (he refers specifically to a letter published in the Times recently about a worker from Moldova who has enjoyed years of work here).
"The real challenge is how to keep it that way," he said, "to still keep the character, but how to do things like lower energy costs, provide more parking… we really have to look at the budget closely."
He stresses the importance of reducing taxes to ease the pressure on island businesses, but the need to balance this with maintaining the school ("I think the school does a good job considering the difficult circumstances of being on an island") and expanding the island's building maintenance and public works projects.
Conservation and deer
McKernan's a proponent of clearly defining the town's beach access points, performing basic maintenance on access points such as brush cutting and putting up "Shoreline access point" signs.
To further conserve the habitat and reduce Lyme disease, he supports complete eradication of deer, which he notes are not an indigenous species to the island. He's glad that hunting properties have been expanded already, and hopes the trend will continue, along with the help of island conservation groups.
"I think that we really have to try to protect Great Salt Pond," he adds. "The immediate stakeholders are the residents and marina owners, but all the rest of us are stakeholders, too." He explained that he wants to see the size of marinas limited and the mooring fields protected.
Overall, McKernan's goal is to give back to the unique community that has given so much to him: "Living on Block Island is a dream come true," he says. " I hope to serve on the Town Council in order to help us remain special, conserve our land and deal with our challenges."

subset: commoncrawl


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For couples that can't conceive a baby within a year – a segment that includes 6 percent of U.S. women aged 15-44 years old – the next stop is often a fertility clinic for tests, procedures and a lot of uncertainty.
Thanks to the research of an Upstate physician, some women struggling with infertility may be able to bypass one of the most common alternative treatments: the multi-week and multi-step in-vitro fertilization (IVF) procedure.
For 25 years, Dr. Bruce Lessey with the Fertility Center of the Carolinas has researched the impact of endometriosis on fertility and how its treatment might lead to successful pregnancies.
Often painful, endometriosis is a condition that occurs when tissue that normally lines a woman's uterus, called endometrium, grows outside the womb. Lessey said endometriosis is the cause of infertility issues for up to 45 percent of couples he treats.
For that reason, couples should always explore what role it may play in their infertility before undertaking the potential mental and economic strain of IVF, an expensive procedure rarely covered by health insurance, he said.
"Inflammation is a key element" in endometriosis, Lessey said. Inflammation of the uterine lining is a part of normal menstruation, but "there has to be a process to shut it off so a woman can have a baby," he said. With endometriosis, inflammation doesn't resolve and creates an immune response that won't go away.
However, it is reversible, Lessey said. The preferred treatment is surgery. Endometriosis causes "implants" of abnormal cells, he said. "You remove the implants and the inflammation goes away quickly."
After treatment, Lessey says his patients experienced a 70 percent pregnancy rate, often without IVF. Many are pregnant within the first two months post-op, he said. "They're just not ready to believe that – they think they're infertile, and they aren't." Because endometriosis can be mistaken for other conditions like irritable bowel syndrome and bladder issues, there is an 11-year diagnosis delay of the condition in the United States, Lessey said.
Some doctors do not consider endometriosis as a cause for IVF failures, he said. Lessey cited a patient who underwent seven failed IVF procedures and came to him despite other doctors' encouragement to try IVF again, he said.
"She did have endometriosis, we did fix it. The next month, she had embryos implanted and is now 22 weeks pregnant with twins," he said.
Lessey and Dr. Steven L. Young, associate professor in obstetrics and gynecology at the University of North Carolina Chapel Hill, have discovered through research that endometriosis is also connected to how the body reacts to progesterone, a hormone that plays a vital role in maintaining a pregnancy. Progesterone resistance is a normal occurrence in a woman's menstrual cycle and the endometriosis "actively turns off the receptors for progesterone," said Lessey. "That process comes earlier in women with endometriosis, caused by the inflammation."
The pair is presenting their findings at the World Congress on Endometriosis in Brazil next week.
In addition, Lessey and Young have developed an endometriosis test, which detects an inflammatory marker associated with endometriosis. Currently used for research purposes, the test has revealed that roughly 96 percent of women who have endometriosis also have the inflammatory marker, he said.
"We can find almost every person with endometriosis, no matter what stage or grade they have. It's the first test of its kind and it will change the way we approach it. So diagnosis over 11 years will go away," Lessey said.
Using the test to determine if endometriosis is the cause of unsuccessful IVF procedures "could save couples millions and millions of dollars of wasted money," he said. - See more at: http://www.greenvillejournal.com/life-culture/3124-closer-to-a-family.html#sthash.Efe0AtgQ.dpuf]]>
Operating in the dark would be challenging for most surgeons. But for Indiana University Health's Dr. Emma Rossi, a dimly lit room can be as critical as a scalpel.
Rossi has been testing a new procedure to track the spread of gynecological cancers. She injects a fluorescent dye that glows in the dark into a patient and dims the lights in the operating room. Then she uses infrared imaging to track the path the cancer might have taken.
"We're trying to find the road that the cancer traveled on, because otherwise the road is invisible," said Rossi, an assistant professor of obstetrics and gynecology at the Indiana University School of Medicine.
Other doctors do this procedure, but it lacks government approval. Nor is there any evidence that it results in better outcomes than traditional surgeries.
So Rossi is leading a multicenter trial to compare old and new methods for treating gynecological diseases such as cervical and uterine cancer.
First, Rossi injects the dye that will light up the lymph nodes. She removes the ones that the dye pinpoints. Then she proceeds as usual, taking out the patient's uterus and other lymphatic tissue. A robot assists her, and the operation is minimally invasive, entailing only a few narrow incisions.
After the surgery, pathologists check lymph nodes for cancer. Often uterine cancer grows slowly and will not have spread. But when it has, Rossi hopes the dye will have located any cancerous nodes, indicating the patient should undergo chemotherapy.
Fewer side effects?
"It works; you can find lymph nodes with it," Rossi said. "But are these the lymph nodes that the cancer is in? We want to see that wherever there's cancer in the lymph nodes, that it's always in the lymph nodes that had dye."
Current treatment of gynecological cancers involves removing all tissue that could contain affected lymph nodes. That comes with the risk of side effects and complications, including swollen legs and nerve injuries.
The new procedure, called sentinel node mapping, could greatly reduce the number of lymph nodes that need to be removed.
A definitive answer could arrive too late to help Pamela Flannagan, a 68-year-old Avon, Ind., resident, but that didn't stop her from agreeing to participate in the trial.
A few years out from a leukemia diagnosis, Flannagan recently learned she had uterine cancer. She went to Rossi for a pre-surgical consultation and heard about the trial.
"I said, if it would help someone else, I would be glad to do it," she said. "I hope it helps someone down the road and me, too."
Lymph node mapping already helps treat other cancers, such as breast cancer. But cancers in organs that lie deep in the abdomen, such as gynecological ones, haven't proved as amenable to the technique.
Doctors tried using a radioactive substance to find the nodes. That, however, required personnel and a Geiger counter, making it time-consuming and expensive. They also tested a blue dye that was difficult to see.
Then a University of North Carolina gynecologist tried a fluorescent dye used in colon cancer. Not only did the compound stay in the lymph nodes long enough for doctors to find it, it also glowed through tissue, which could aid doctors working on obese patients.
That physician, Dr. John Boggess, a professor of gynecologic oncology at the UNC School of Medicine, assigned one of his fellows to develop a protocol for treatment.
Now he's participating in a trial that his former fellow, Rossi, is leading to show that it works. Other trials are under way but nothing approaching the scale of Rossi's, he said.
If this works, the process could help improve diagnosis and treatment. In some instances, doctors know cancer comes back even though they did not detect it in the lymph nodes. It's possible this technique will help doctors find the earliest beginnings of cancer that have previously gone unnoticed.
Click here for entire article.]]>
Dr. Parisi most recently served as ABMS BOD Chair Elect. She has been a member of the ABMS Board and Executive Committee since 2009, and served as Secretary-Treasurer from 2009 to 2012. Dr. Parisi has chaired and served as a member of numerous ABMS committees, including the Research and Education Committee, the Finance and Audit Committee, the Governance Committee and the Database and Information Technology Advisory Committee.
Since 2010, Dr. Parisi has served as the Dean of the Wayne State University School of Medicine, the nation's largest single-campus medical school. From 2010 to 2012, Dr. Parisi served as Co-Chair of the Liaison Committee for Medical Education, which accredits medical schools in the United States and Canada. She was Director of the Division of Maternal Fetal Medicine for the American Board of Obstetrics and Gynecology (ABOG), and a Director of ABOG from 1998-2008. Dr. Parisi is Board Certified by the American Board of Obstetrics and Gynecology with a subspecialty certificate in Maternal-Fetal Medicine, and is meeting Maintenance of Certification (MOC) requirements.
"Valerie Parisi is a proven leader who shares ABMS' mission to improve the quality of health care through setting professional standards for lifelong certification in partnership with our Member Boards," said Lois Margaret Nora, MD, JD, MBA, ABMS President and Chief Executive Officer. "As a national leader in medical education as well as in the evaluation and certification of physicians, she is well prepared to lead the implementation of ABMS' program for continuing professional development for Board Certified physicians."
Dr. Parisi succeeds Thomas E. Norris, MD, who served as ABMS BOD Chair from 2012 to 2014. He noted that "Valerie's medical leadership in many roles and record of outstanding contributions to ABMS will serve the Member Boards well as we focus on increasing and demonstrating the value we bring to those we serve."
Dr. Parisi received her medical degree from Brown University, where she was enrolled in the institution's first seven-year medical degree class. She received her Master of Public Health degree in Maternal and Child Health from the University of California-Berkeley School of Public Health and her Master of Business Administration degree from the University of North Carolina Kenan-Flagler School of Business. Dr. Parisi completed her residency in Obstetrics and Gynecology at Women and Infants Hospital of Rhode Island and her fellowship training in Maternal and Fetal Medicine at the University of Wisconsin Center for Health Sciences.
ABMS Media Contact: Rich Waters
VP Marketing & Communications
(312) 436-2626
The prize was awarded at the banquet on Saturday night by Program Chair A. Kellett Letson, MD.
Also on Saturday evening, the Robert A. Ross Society held a reception at The Pinehurst Resort.
Below are some pictures from that event. Click here if pictures are not visible.]]>


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Freshly fired, Aiden visits Nolan. He's ready to put a stop to Emily's revenge games. His solution? Bankrupt the Graysons. Alas, their bank accounts are unhackable thanks to the Fa1c0n. So Nolan goes to pay Edith a visit. He makes a deal with her: If she helps him track down the lost Grayson son, he'll help free her. But there's no son to track down, according to the Fa1c0n. Victoria had her henchmen pay Patrick $5 million to disappear years ago. "She's playing you," Edith declares. Still, there's the small matter of Carrion. The Fa1c0n reveals that she planted a code in the program, meaning it can't function without it. So either way, she's getting out of jail. It's just a matter of whether it's Nolan or the Initiative who spring her. But since she likes Nolan, she leaves him with a parting riddle, like any good master villain. If he can solve it, he'll have her secret code.
Jack meets up Conrad at his campaign headquarters, but he's really looking for Ashley. He wants to know if he really was the reason behind Emily and Daniel's first breakup. Let's pause for a second here. How does Jack not believe he is at least in some way responsible? It doesn't make sense to me. Anyway, Ashley takes this time to admit that she was the one who spilled the beans about the Jack/Emily kiss. "She always seems to get what she wants," Ash adds petulantly. "People like them always do." "Not him, not this time," Jack says, looking at Conrad.
Bit of a dull engagement party, huh? Then again, how could it possibly compare to last year's? Victoria does get MVP for delivering a surprisingly sweet toast, which started with this ace line: "If at first you don't succeed, try, try again." She pulls Emily aside for a heart-to-heart, but Ems is holding all the cards. They're moving to Paris, whether Victoria likes it or not. "You'll make a terrific grandmother, Victoria," she says. "We'll put a picture up, so they can see."
Charlotte can't hold her alcohol. Thankfully, Declan's trolling the streets of NYC like Kick-Ass. "Stalker," whispers Regina, while trying to hurry Charlotte away. Of course, Charlotte has to stop to vomit, a moment that is captured in all its glory by the various photogs trailing her. Declan tries to shield her, but it's no good. She's spotted by a cop, who takes her in thanks to her bigwig last name. That'll be good for Conrad's campaign. (Also, was I the only one who half-expected her to protest that her last name is Clarke?)
Daniel, charmer that he is, takes time out of his engagement party to tell Emily that he fired Aiden. Ems can't understand it: Aiden was supposed to be the fall guy in Daniel's attempt to free himself from the Initiative. But Daniel couldn't ignore the file that Takeda provided him with. You can see Emily didn't expect that. Luckily, Takeda's in attendance, allowing Emily to confront him about his uncharacteristic behavior. "How could you do this?" she asks. "The boy has put you at risk," he answers simply, before revealing that the Initiative is set to strike, and soon. And only he can stop it. Methinks Takeda's channeling Ra's al Ghul just a little too heavily.
NEXT: Emily's porch sees a lot of action


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PURE ACTION Run, jump and slide from ropes, dodge rocks! Not enough? There is much more in Manuganu. Avoid swinging hammers and jump over moving ice blocks. Don't get burned and jump between walls to collect coins and medallions. Break stone blocks and activate platforms before you fall into fog and much more... A RUNNING ADVENTURE Manuganu is a 3D side- scroller running game, in which you...
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Contact Audrey's: (310) 440-4505
*Zoom in where available by hovering over the image above.
The olive branch is an international symbol of peace and a token of goodwill. Designed by Michael Aram, this serving dish conveys this message to all who are welcomed into your home. Perfect for serving hors d'oeuvres or antipasto.
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Atomic London wins Grundig ad account
Grundig, the appliances brand, has appointed Atomic London to handle its UK advertising account.
Grundig: ad account goes to Atomic London
Beko, which owns Grundig, plans to introduce the brand's range of appliances across the UK. Atomic London has been briefed with developing and delivering the comms and marketing programme for the launch.
It will work alongside the German agency Jung von Matt. TBWA remains the agency of record for the Beko brand.
Teresa Arbuckle, Beko's UK and Ireland marketing director, said: "We were keen to find an agency that could help us to define and build the brand values. We need to emotionally reconnect with the British audience by clearly demonstrating the qualities that the brand and its products imbue.
"We needed to choose an agency that can activate this strategy all the way through the consumer journey to help the brand to realise its full potential. We have high expectations for growth and are excited by this partnership."
Nick Fox, a partner at Atomic, said: "Grundig is a deep brand with an inspiring brand story and fabulous products."
This article was first published on campaignlive.co.uk
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December 19, 2013
Bryan Witzmann earns first team All-American honors at South Dakota State
Three South Dakota State football student-athletes, including repeat first-team selections Bryan Witzmann and Zach Zenner, were named Wednesday to The Sports Network Football Championship Subdivision All-America Team. Witzmann, a senior offensive tackle who graduated from Somerset...
sports / high school
December 19, 2013 - 9:23am
December 12, 2013
Gaelin Elmore adds another all-state football honor
The Associated Press All-State Football Team was announced on Tuesday and Somerset senior Gaelin Elmore was again selected as a first team all-state player. Elmore was named as a first team selection at the defensive end-outside linebacker position. He had already been named as a...
sports / high school
December 12, 2013 - 3:21pm
Bryan Witzmann, Robbie Flom earn college all-conference honors
The South Dakota State University football team was beaten by Eastern Washington University on Saturday, 41-17, in the second round of the Football Championship Subdivision playoffs. With the SDSU loss, the college football career of Somerset native Bryan Witzmann comes to an end....
sports / high school
December 12, 2013 - 2:59pm
November 27, 2013
Somerset's Jon Bucklew, Gaelin Elmore earn all-state honors
Two Somerset High School standouts have received all-state honors for their performances during the 2013 fall sports season. Somerset seniors Jon Bucklew and Gaelin Elmore were recognized for their accomplishments in the fall season. Elmore was a two-way selection on the Wisconsin...
sports / high school
November 27, 2013 - 2:40pm
November 21, 2013
Somerset football team stopped in bid to reach third straight state championship game
The pursuit of a third straight trip to the WIAA state football championships by the Somerset football team fell two points short. The Spartans were defeated by the Winneconne Wolves 16-14 in the WIAA Division 4 state semifinal game played in Marshfield last Friday. The Spartans...
sports / high school
November 21, 2013 - 11:34am
November 15, 2013
Somerset football won't make third straight trip to WIAA state finals
A shaky first half was simply too much for the Somerset football team to overcome in its quest to return to the WIAA state championship game for the third straight year. The Spartans made an empassioned comeback after trailing Winneconne 9-0 at halftime. The Spartans came back,...
sports / high school
November 15, 2013 - 10:27pm
Somerset football plays in state football semifinals on Friday
The Somerset football team has the chance to play in its third straight WIAA state championship game. The Spartans advanced to the WIAA Division 4 state semifinal game by using a flawless performance to win at Ellsworth last Friday, 14-7. The Spartans will face Winneconne in the...
sports / high school
November 15, 2013 - 9:43am
November 8, 2013
Somerset football gets another shot at Ellsworth
The Somerset football team gets the chance to avenge its only loss of the season. The Spartans will play at Ellsworth at 7 p.m. this Friday in Level 3 of the WIAA Division 4 football playoffs. The Spartans advanced through Level 2 with a sometimes shaky performance, beating Prescott...
sports / high school
November 8, 2013 - 3:48pm
November 1, 2013
Somerset, Ellsworth football teams advance to Round 3 of playoffs
The Somerset and Ellsworth football teams continued on their collision course, winning their second round games in the WIAA Division 4 playoff games on Friday night. Somerset and Ellsworth will meet in Ellsworth next weekend. The game will be played at 7 p.m. Somerset advanced...
sports / high school
November 1, 2013 - 10:46pm
October 31, 2013
Somerset football hosts Prescott Friday in second round of WIAA playoffs
The Somerset football team inflicted one of the most one-sided, hellacious beatings in Spartan football history on Friday night. In Somerset's first nine offensive plays from scrimmage, the team scored six touchdowns, including scoring on four consecutive offensive plays. With...
sports / high school
October 31, 2013 - 10:46am
Schutz shoots down St. Croix Central football team 51-0
Dennis Schutz was a one-man wrecking crew on Friday night. He wrecked any hopes the St. Croix Central football team had of pulling off an upset in the opening round of the WIAA Division 4 regional playoffs. Schutz ran for 289 yards and five first half touchdowns in leading the...
sports / high school
October 31, 2013 - 10:33am
October 25, 2013
Somerset football crushes Northland Pines, Ellsworth topples St. Croix Central
Ever see a football team score 45 points in a quarter? Fans who attended Friday's playoff game in Somerset did. The Somerset football team scored five touchdowns in its first eight plays from scrimmage to build a 45-0 lead in the first 11 minutes of the game. The Somerset starters...
sports / high school
October 25, 2013 - 10:30pm
October 24, 2013
Strong halfback play makes Somerset football team whole
The offense of the Somerset football team has been making sharp improvements on a weekly basis by getting diversity in its attack. The Spartans won the battle for second place in the Middle Border Conference last Friday, defeating Durand 38-19 in the regular season finale for both...
sports / high school
October 24, 2013 - 10:21am
New Richmond football team ends season with dramatic victory
The validation for a season's worth of hard work came in the final two weeks of the season for the New Richmond football team. The Tigers put together their first winning streak of the season in winning their final two games, to finish the season with a 3-6 record. The Tigers...
sports / high school
October 24, 2013 - 9:58am
St. Croix Central qualfies for WIAA football playoffs, thunders past Elk Mound 41-6
After the first play from scrimmage, the St. Croix Central football team had its chance at a place in the WIAA state football playoffs under control. The Panthers handed the ball to senior Dante Carlson on that opening play and he responded by racing 71 yards down the Panther sideline...
sports / high school
October 24, 2013 - 9:20am
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kawamike Posted:
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Anthony Rizzo delivers on the hype, for one game at least
BY GORDON WITTENMYER firstname.lastname@example.com June 26, 2012 10:32PM
what's in the cards?
If Gregg Jefferies had lived up to the hype surrounding his rookie card,he would have been a first-ballot Hall of Famer. The 21-year-old Mets hopeful was ordained a "Future Star" on card No. 233 (a look that inspired today's back page) in the 1989 Topps set and had collectors buying packs by the box. The card's value was $3 out of the pack and continued to soar until reality set in as Jefferies failed to hit .300 in three full seasons with the Mets. Card No. 233 will set you back $1 today.
Article Extras
Updated: July 28, 2012 6:36AM
It was exactly like Anthony Rizzo pictured it.
Well, except for getting lost. And no green door.
''My first thought coming here was sliding that green door open like in 'Rookie of the Year,' the movie,'' said the 22-year-old savior-slugger after his successful Cubs debut Tuesday night. ''I didn't see [the door]. I got lost coming in.''
But he more than found his way by the time it counted.
The most anticipated Cubs rookie since — well, OK, the list is too long to print — went 2-for-4
with a go-ahead, two-out double in the fourth inning to live up to the hype, for at least one day, in a 5-3 victory over the New York Mets at Wrigley Field.
''It was awesome,'' said Rizzo, who might as well have been talking for the front office and fan base, as well.
After months of breathless anticipation, the kid with the monster minor-league numbers debuted to throngs of media, pregame embraces from the team's brass, including chairman/owner Tom Ricketts, and a standing ovation the first time he walked to the plate as the No. 3 hitter.
''I'm here to stay,'' he said with a big smile before the game.
And people thought Theo Epstein was a savior?
That was before the broad-shouldered Rizzo stepped into the left-handed batter's box like he owned the place and gave fans a preview of what Epstein and his posse believe is a coming attraction for the better part of the decade.
''It's pretty exciting,'' said All-Star shortstop Starlin Castro, who debuted to his own buzz two years ago, ''mostly because he's a good player. A lot of people look at him because he's supposed to be a superstar.''
Castro knows as well as anyone that he's the yang to Rizzo's yin in the Cubs' rebuilding plan.
''Yeah, that's what I want to be,'' he said. ''Me and him, the two franchise [players]. … Let's see what happens. The team's struggling a little bit now, but it's going to be good.''
When? How long will it take? That's probably up to the next couple of hyped prospects that come up.
But this was clearly the first game of the Epstein-Jed Hoyer Era, which makes the Cubs' 1-0 after the first day of the rest of the franchise's life.
As the message board outside Murphy's Bleachers on Sheffield and Waveland read: ''Welcome Rizzo! The Future Starts … 2Nite.''
One block down, on the board outside O'Malley's: ''Hey Rizzo, we just Mets you and this is crazy.''
No crazier than a kid with barely one failed month in the big leagues making his Cubs debut in the marquee spot in the batting order, with the manager saying he plans to leave him there.
''He didn't act like much of a kid tonight, that's for sure,'' said Sveum, who raved about Rizzo's general calm and two-strike approach before hitting an off-speed pitch the other way for the double.
Talk about pressure. Right?
''Oh, yeah,'' Rizzo said. ''This is the best. Pressure comes with any sport, and being in such a big market, it's even better.''
If he doesn't understand the century behind the hype, the depth of the desperation of this place, Rizzo at least seems to have the right temperament.
''I was the savior last year, too, and that's why I think it's easier this year to come up,'' said Rizzo, who hit .141 with just one homer in six weeks with San Diego last year. ''Hopefully, this is just a building block of what is here to come in the city and the organization.''
Sounds good. But, of course, this isn't San Diego. And the Padres don't have 104-year-old ghosts to exorcise or the shoes of Hall of Famer Billy Williams to fill as the next big lefty slugger.
''We aren't going to talk about that,'' said Williams, who chatted briefly with Rizzo on Tuesday and told him to relax and enjoy himself.
But if Rizzo has the goods to be the next Williams the Cubs have hungered for? ''Hopefully, this could be the kid,'' Williams said.


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Pepper-Crusted Beef Tenderloin with Horseradish Sauce Recipe
Submitted By:.
- 1 whole beef tenderloin, about 4 pounds and 3 inches in diameter, trimmed and tied
- olive oil
- 1 tablespoon coarsely ground Peppercorns Royale
- 1 tablespoon Sel de Provence
- For Horseradish Cream:
- 1/2 cup plus 2 tablespoons crème fraîche or sour cream
- 3 tablespoons prepared horseradish
- 1-2 tablespoons crushed pink peppercorns
- kosher salt to taste
Preparation Instructions
Heat oven to 425 degrees.
Bring tenderloin up to room temperature about 1 hour. Pat meat with paper towels to
dry, then lightly coat all over with oil. Sprinkle evenly with sel de provence and ground
peppercorns, firmly pressing to help them adhere.
- Set a cast-iron griddle or large roasting pan over two burners and heat over high until hot.
Carefully rub griddle lightly with oil. (If using a roasting pan, add enough oil to barely
coat the bottom of the pan.) Heat until hot but not smoking, then place the tenderloin on
the griddle and sear on all sides, about 3 minutes per side. Use tongs to transfer beef to a
rack set in a rimmed baking sheet.
- Roast until an instant-read thermometer inserted into thickest part registers 125 degrees
for medium-rare, 20 to 30 minutes. Let rest 10 minutes.
- Transfer tenderloin to a carving board and slice to desired thickness (about 1/2 inch is a
nice size) before serving.
Serve with Horseradish Cream:
- Whisk crème fraîche (or sour cream) in a medium bowl until thickened and soft peaks
start to form, 1-2 minutes.
- Fold in horseradish and peppercorns; season with salt and more horseradish, if desired.
DO AHEAD Sauce can be made 3 days ahead. Cover; chill.
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Kiwis Marcus Daniell, Marvin Baker and Dan King-Turner all had good doubles results over the weekend at their respective tournaments.
Marcus Daniell and German partner Gero Kretshmer won the doubles title at the US$10,000 Men's Event in Antayla-Belconti, Turkey, thrashing Tomislav Brkic (BIH) and Mislav Hizek (CRO) 6-0 6-2 in the final.
Meanwhile, Marvin Barker (below) reached the final of the doubles at the US$15,000 Men's Futures Event in Little Rock, USA.
Barker teamed up with Edward Corrie of Great Britain to reach the final. The pair lost in the third set super tiebreak against Gregory Ouellette and Tennys Sandgren (USA) 6-4 6-7(2) [8-10].
Fellow Kiwi Dan King-Turner reached the doubles semi-finals with John Millman of Australia at the US$15,000 in Kaohsiung, Taipei. The duo knocked out fourth seeds Hsin-Han Lee and Hsien-Yin Peng (TPE) in the quarterfinals 6-3 7-6(3). In the semi-finals the pair lost to top seeds Denis Matsukevitch (RUS) and Frederik Nielsen (DEN) 6-3 3-6 [8-10].
Meanwhile on the singles front, King-Turner lost to fourth seed and world number 190 Amir Weintraub (ISR) 6-3 3-6 7-6(5). Fellow Kiwi Jose 'Rubin' Statham reached the singles semi-finals of the US$10,000 Men's Futures Event in Ho Chi Minh City, Vietnam before being forced to retire in the semi-finals.
Pro Circuit


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For our Gaming PC builds below $900 it was easy enough to choose where we wanted to put our money because there was always a lot of improvement needed in performance, which was always put as our priority. Going forward from here you'll have to decide whether you're going to continue to focus on performance or move towards improving your other components which aren't essential towards performance.
I'm happy with the FX-8120 and 2500k we used in our $900 build, but with the additional $100 you could consider upgrading to the i7-2600k or the FX-8150. Personally, I'd rather upgrade other areas.
There are a lot of people who would call for a GPU upgrade over the HD 6950 and GTX 560Ti we recommended in the last build. If you want additional GPU performance, then in this price range you could go with the GTX 570 or the HD 6970. My preference would be to pass this upgrade in favor of a larger hard drive, 64GB SSD for Intel Smart Response Technology, and/or more Ram.
For me, this is where half of the additional money we get for this build should go. I recommend 16GB of Corsair XMS3 or Vengeance Ram with a quad channel kit.
At this price point I recommend the Asus P8Z68-V/GEN3 for Intel builders or the GIGABYTE GA-990FXA-UD3 for AMD enthusiasts.
Our 500GB hard drive is in dire need of upgrade, especially if you store as much crap on your computer as I do. For performance we'll go with the 1TB Western Digital Black WD1002FAEX. For capacity go with the Western Digital Caviar Green WD20EARX.
If you don't plan on going with a Blu-ray drive, then I'd recommend sticking with an inexpensive DVD±RW like the Asus 24xDVD±RW Drive.
If you want to upgrade your case, then I highly recommend the HAF Mid Tower RC-922M-KKN1-GP or the relatively new Corsair Carbide Series 500R (CC-9011012-WW) or for a full tower something like the Antec DF-85.
At this point you should still be fine with a 650+ watt PSU that is 80 PLUS certified. Because of the insane rebates available for the OCZ ModXStream Pro 700W I highly recommend it.
In my opinion the best bet for your $1,000 gaming PC build is to improve the overall functionality of your machine by improving the capacity and speed of your hard drive and adding some ram.
As with all of our builds, here's a table which breaks down the build above:
|AMD PC Gaming Build
|Price / Deals
|Intel PC Gaming Build
|Price / Deals
|Total Price:
|AMD FX 8120 8-Core Processor 3.1 8 Socket AM3 - FD8120FRGUBOX
|Intel Core i5-2500 3.3 GHz 6 MB Cache Socket LGA1155 Processor
|XFX AMD Radeon HD 6950 800M 2 GB DDR5 Dual MiniDP HDMI Dual DVI PCI-E Video Card HD695XCNFC
Rebate Available.
|EVGA GeForce GTX 560 Ti Superclocked 1024MB GDDR5 PCI-Express 2.0 Graphics Card - Lifetime Warranty 01G-P3-1563-AR
Rebate is available.
|Corsair XMS3 16GB (4x 4GB) PC3-10666 1333MHz DDR3 Memory Kit for AMD and Intel Dual Channel Processors CMX16GX3M4A1333C9
|Corsair 16 GB Vengeance Blue Low Profile 1600mhz PC3-12800 240-pin Quad Channel Kit CML16GX3M4A1600C9B
|GIGABYTE GA-990FXA-UD3 AM3+ AMD 990FX SATA 6Gb/s USB 3.0 ATX AMD Motherboard
|ASUS LGA 1155 - Z68 - PCIe 3.0 and UEFI BIOS Intel Z68 ATX DDR3 2200 LGA 1155 Motherboards P8Z68-V/GEN3
|Hard Drive
|Western Digital Caviar Green 2 TB Desktop Hard Drive WD20EARX
|Western Digital Caviar Black 1 TB SATA III 7200 RPM 64 MB Cache Internal Desktop Hard Drive Bulk/OEM - WD1002FAEX
|Asus 24xDVD±RW Drive DVD-RAM/±R/±RW 24x8x16x(DVD) 48x32x48x(CD) Serial ATA Internal OEM DRW-24B1ST - 19
|Same as AMD Build
|Cooler Master HAF 912 Mid Tower ATX Case (RC-912-KKN1)
|Same as AMD Build
|OCZ ModXStream Pro 700W Modular High Performance Power Supply compatible with Intel Sandy Bridge Core i3 i5 i7 and AMD Phenom
|Either go with the Corsair model to the left or save yourself another $30 by going with the OCZ ModXStream Pro 700W Modular High Performance Power Supply which always has great rebates available.


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This is a DRY, classic pink with fine and persistent mousse, hints of red fruits and floralness with an elegant and long finish. This cuvée of 90% Pinot Noir and 10% Chardonnay is produced by the long (6 months) Charmat method. Fantinel winery spans 40 years and three generations. Its a small, family-owned winery that has slowly grown into a major wine company operating out of Friuli. Fantinels focus is to grow and vinify wines that are the truest and purest expressions of the micro-climates from which they originate. Fantinel was founded in 1969 by Mario Fantinel, a hotelier and restaurateur who decided to purchase vineyards near Dolegna del Collio.
Below is a listing of the wine review scores we frequently reference in our notes. While these sources remain an excellent source of information, we always recommend that you trust your own palate. Scores in these publications often represent the personal taste of an individual critic, which may not always coincide with your own. We have a huge team of excellent wine professionals that can match wines you've had in the past with new arrivals that meet your flavor profile.
The item you have chosen is not in stock in our retail stores or within our main
2009 Querceto Chianti Classico Riserva (Elsewhere $24)
2012 Erik Banti "Carato" Toscana
2010 Cantele Salice Salentino Riserva
2012 Baccinetti "La Saporoia" Rosso di Montalcino
Montechiara Prosecco DOC


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EndGames Up 'Til Midnight Jam
EndGames Productions
Thursday, August 1, 2013 at 10:00 PM - Friday, August 2, 2013 at 12:00 AM (PDT)
Who's Going
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Sara Haughty
San Francisco, California
San Francisco, California
Luke Picard
London, United Kingdom
London, United Kingdom
Rick Vespucio
Florence, Italy
Florence, Italy
Event Details
Every Thursday at 10:00pm at Stage Werx Theatre, an amazing group of people get together to play, perform, and enjoy each other's company. You can be a part of this crazy community if you just show up with your team or sign up by yourself. Thursday night just got one more excuse to stay up late and have some fun with some of Bay Area's best improvisors.
Doors open at 9:30pm. Sign-ups start at 9:45pm. Non-alcoholic beverages for sale at the door.
Have questions about EndGames Up 'Til Midnight Jam? Contact EndGames Productions
When & Where
The Dark Room
2263 Mission St
San Francisco,
Thursday, August 1, 2013 at 10:00 PM - Friday, August 2, 2013 at 12:00 AM (PDT)
Add to my calendar


text:
25th May, 2011 | Listens: 10,353 - 01. T-Pain Tapestars Intro 02. Try'n (FT Ace Hood) 03. Winning (Prod By Big Steve..
Wiz Khalifa – Maan
Drake – Days In The East
Drake – Draft Day
Jay-Z & Jay Electronica – We Made It (Freestyle)
50 Cent Ft. Yo Gotti – Don't Worry Bout It
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place? How does today's uncertainty about authority affect the nation's ability to execute any given policy on cyberdeterrence?
Cyberattack can be used as a tool for offensive and defensive purposes. How should cyberattacks intended for defensive purposes (e.g., conducted as part of an active defense to neutralize an incoming attack) differ from those intended for offensive purposes (e.g., a strategic cyberattack against the critical infrastructure of an adversary)? What guidelines should structure the former as opposed to the latter?
Research contributions in these areas will have greater value if they can provide concrete analyses of the offensive actors (states, criminal organizations, patriotic hackers, terrorists, and so on), motivations (national security, financial, terrorism), actor capacities and resources, and which targets require protection beyond that afforded by passive defenses and law enforcement (e.g., military and intelligence assets, critical infrastructure, and so on).
The research agenda described in the questions above is intellectually challenging and fundamentally interdisciplinary. The committee hopes that a variety of scholarly communities, including those in political science, psychology, and computer science and information technology, are able to find ways of working together to address the very important question of deterring cyberattacks against the societal interests of the United States.
Moving forward and in accordance with the requirements of the relevant contract, the committee has commissioned a number of papers that address some of the questions articulated above. Drafts of these papers will be discussed in a workshop to be held in June 2010. Although resource limitations will constrain the number of papers commissioned, the committee is of the belief that all of these questions are important and deserve further significant attention.
John D. Steinbruner,
Committee on Deterring Cyberattacks
Computer Science and Telecommunications Board
Division on Engineering and Physical Sciences
Division on Policy and Global Affairs


text:
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Shoot for the moon with sleek modern tailoring and stretch cotton comfort. Our slim-fit Photographer pant is workday polished with a shirt and tie, but also up for weekend happenings under a polo or sweater.
- Slim fit, sits below the waist, straight leg
- Hidden hook and button closure with zip fly
- Slant hand pockets, welt back pockets with buttons
- Cotton/Spandex
- Machine wash
- Imported
My New Favorite Dress Pants I recently purchased my first pair of Photographer pants, after much frustration in looking for a good-fitting pair of tailored brown dress pants that weren't tight in the waist or the crotch. I was very impressed at how tailored these pants are, without looking like "skinny jeans." They are very comfortable and I am very pleased with the way the fit me. I've always been on the thin/athletic side, and most dress pants were too "baggy" for my taste. My only complaint was the 32-30 was too long, and I had to have them altered before I was able to wear them. This was the first time I'd had to alter the length in a pair of Express dress pants. January 22, 2014
Best Pants Ever This dress pants a great. I now own practically all the colors . I believe they are true to there size unlike a lot of reviews I have read. and they fit great. The are just slim enough for a perfectly tailored look, the only aspect of these pants that a down side is that the material wrinkles easily, but if you bring them to the dry cleaners that solves the problem, i would recommend the pants to anyone that wants a sleek modern look, the money that you pay for them is worth it January 9, 2014
pretty good but... 5'9 165 lbs 32x30. fit is perfect for these pants and the cut is great. my only problem with these pants is that when you wash them, the crease comes out immediately. not sure if that's how all cotton pants are since all my dress pants are wool. note: these pants, while cotton, should probably only be dry cleaned unless you want them to turn into chinos. Also, the pants are darker than they look in the picture but still look good. Wear with a french blue 1MX for a sweet look that will make your friends jealous. December 27, 2013
DO NOT PUT THESE IN THE DRYER Got these for my BF, one wash and the allure wore off. July 13, 2013
Photographer style pants rock!! I currently own 3 different colored Photographer pants (this brown one being one of the three) and they are great. I was somewhat satisfied with their Producer cut but as long as the Photographer style is "produced" I will buy just those. The main difference I see between the Photographer and the Producer is how wide the thigh area is, the photographer being slimmer. The fit is amazing. I am a 28x30 (I used to buy 29x30 but adding jogging 3 times a week to my workout routine put me back at 28 inch waist!!) and it took just a couple of try-outs to realize the cut is much more modern, without being trendy and it flatters all that needs flattering ;-) I highly recommend this style. Buying the black ones soon!!! June 19, 2013


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Arizona Cardinals
Tom Moore philosophy: 'You do what your players can do'
Tom Moore has a wealth of experience as an NFL coach.
Hired by the Arizona Cardinals as assistant head coach/offense, Moore has been helping professional offenses since 1977, including stints with seven different teams.
So what kind of system will the coaching veteran bring to his eighth organization?
A non-system, system.
"Football is a game of people," Moore said at his introductory press conference Friday. "There's lots of systems, and one of the things that you want to make sure that you do and that's what we're doing right now, you don't come in with preconceived ideas and say 'I'm Tom Moore and this is what we're going to do.'"
Moore said that type of mentality won't work.
"You've got to do what your players can do," he said. "Find out what they can do, find out what they're the best at, find out what their strengths are and then make sure that you take advantage of their strengths and maximize them."
Adding that a coach's job is to "make sure that you give your players a chance to be the very best they can be," Moore's perspective appears to be different from that of the previous coaching regime.
Gone is talk about how "the system works" or "the system is proven", and in its place is the idea that it would be best to plan around the talent on the roster.
"You do what your players can do," Moore said.
That means learning a roster full of players who struggled last season, so finding strengths, at least from a fan's perspective, may be a difficult task. But rest assured, Moore says, every player has strengths.
"You've got to play to your players' strengths," he said. "What can they do?"
Moore said at this point the coaching staff doesn't know what the players can do, so it would be "premature" to say what exactly the offensive game plan will be.
Whether this mentality and style will be enough to transform an offense that was dead last in the NFL remains to be seen, but at the very least, any change Moore and head coach Bruce Arians make probably can't hurt.
And given that Arians was hired in large part because of his track record on the offensive side of the ball, both he and Moore are expected to turn things around.
"At Indianapolis we had certain things that we felt we could do that we could take advantage of and Bruce was a very big part of that," Moore said. "We worked together for three years; he was with Peyton Manning...it wasn't a Tom Moore system, it was an Indianapolis Colts system and Bruce was very integral in that."
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- Brock Huard, ESPN 710 Seattle host - Friday December 19Brock Huard believes Sunday's Cardinals-Seahawks game is going to be a brawl.
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- Danny O'Neil- ESPN 710 Seattle - Friday December 19Danny O'Neil describes the feeling in Seattle leading up to this weekend's game.
- Bickley Blast - Friday December 19This Sunday will be quite the spectacle, with the Cardinals taking on the Seahawks.
- Warren Moon, Seahawks radio analyst - Friday December 19What should the Cardinals expect to see from the Seahawks this Sunday?


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REMICADE® in Pediatric Crohn's Disease (PCD)
REMICADE® has been approved for the treatment of pediatric patients with moderate to severe Crohn's disease who had an inadequate response to conventional therapies.
Because the presentation of CD in children is similar to that in adults, the same pathophysiologic mechanisms involving tumor necrosis factor-alpha (TNF-a) are believed to be present in children.1
The pivotal pediatric trial of REMICADE®, "A Randomized, multicenter, open-label study to Evaluate the safety and efficacy of Anti-TNF-a Chimeric monoclonal antibody in pediatric subjects with moderate to severe Crohn's disease" (REACH study), was conducted to determine efficacy and safety in patients 6 to 17 years of age.1
REACH trial background1
REACH was a multicenter, randomized, open-label, controlled trial, which evaluated the safety and efficacy of REMICADE® in 112 pediatric patients (ages 6 to 17 years). All patients were required to be on a stable dose of azathioprine (AZA), 6-mercaptopurine (6-MP), or methotrexate (MTX); 35% were also receiving corticosteroids at baseline
The primary objective of this trial was to evaluate the efficacy of a 3-dose induction regimen of REMICADE® in reducing signs and symptoms in pediatric patients with moderately to severely active CD. Additionally, the safety profile of REMICADE® in these patients was also evaluated. The secondary objective was to compare maintenance of clinical response and remission with REMICADE® 5 mg/kg administered every 8 weeks or every 12 weeks. REMICADE® 5 mg/kg administered every 12 weeks is not an approved dosing regimen.
Patients included in the trial had moderate to severe CD (Pediatric Crohn's Disease Activity Index [PCDAI] >30). Induction of clinical response, the primary endpoint, was evaluated 10 weeks after the initial infusion. At Week 54, clinical response, clinical remission and change from baseline in average daily corticosteroid use were evaluated as secondary efficacy endpoints. Clinical response was defined as a decrease of ≥15 in the PCDAI and a total PCDAI score of ≤30. Clinical remission was defined as a PCDAI score of ≤10.
Of the 112 patients enrolled in this study, 103 patients were subsequently randomized to REMICADE® 5 mg/kg every 8 weeks (n=52) or every 12 weeks (n=51) through Week 46.
REACH study findings1
Clinical response at Week 10, the primary endpoint, was achieved in 88% of the patients.
In pediatric patients with CD receiving REMICADE® every 8 weeks, 70% (17/24) eliminated steroid use through Week 54 (P<0.001).1
REMICADE® is indicated for reducing signs and symptoms and inducing and maintaining clinical remission in adult and pediatric patients with moderately to severely active Crohn's disease (CD) who have had an inadequate response to conventional therapy.
- Hyams J, Crandall W, Kugathasan S, et al, and the REACH Study Group. Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children. Gastroenterology. 2007;132:863-873.
REMICADE® is indicated for:Crohn's Disease
- Reducing signs and symptoms and inducing and maintaining clinical remission in adult patients with moderately to severely active Crohn's disease (CD) who have had an inadequate response to conventional therapy
- Reducing the number of draining enterocutaneous and rectovaginal fistulas and maintaining fistula closure in adult patients with fistulizing CD
- Reducing signs and symptoms and inducing and maintaining clinical remission in pediatric patients 6 years of age or older with moderately to severely active CD who have had an inadequate response to conventional therapy
- Reducing signs and symptoms, inducing and maintaining clinical remission and mucosal healing, and eliminating corticosteroid use in adult patients with moderately to severely active ulcerative colitis (UC) who have had an inadequate response to conventional therapy
- Reducing signs and symptoms and inducing and maintaining clinical remission in pediatric patients 6 years of age and older with moderately to severely active UC who have had an inadequate response to conventional therapy
- Reducing signs and symptoms, inhibiting the progression of structural damage, and improving physical function in patients with moderately to severely active rheumatoid arthritis (RA) in combination with methotrexate (MTX)
- Reducing signs and symptoms of active arthritis, inhibiting the progression of structural damage, and improving physical function in patients with psoriatic arthritis (PsA)
- Reducing signs and symptoms in patients with active ankylosing spondylitis (AS)
- The treatment of adult patients with chronic severe (ie, extensive and/or disabling) plaque psoriasis who are candidates for systemic therapy and when other systemic therapies are medically less appropriate
Patients treated with REMICADE® (infliximab) are at increased risk for developing serious infections that may lead to hospitalization or death. Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. Discontinue REMICADE® if a patient develops a serious infection or sepsis.
Reported infections include:
- Active tuberculosis (TB), including reactivation of latent TB. Patients frequently presented with disseminated or extrapulmonary disease. Patients should be tested for latent TB before and during treatment with REMICADE®.1,2 Treatment for latent infection should be initiated prior to treatment with REMICADE®.
- Invasive fungal infections, including histoplasmosis, coccidioidomycosis, candidiasis, aspergillosis, blastomycosis and pneumocystosis. Patients may present with disseminated, rather than localized, disease. Empiric anti-fungal therapy should be considered in patients at risk for invasive fungal infections who develop severe systemic illness.
- Bacterial, viral, and other infections due to opportunistic pathogens, including Legionella and Listeria.
The risks and benefits of treatment with REMICADE® should be carefully considered prior to initiating therapy in patients with chronic or recurrent infection. Closely monitor patients for the development of signs and symptoms of infection during and after treatment with REMICADE®, including the possible development of TB in patients who tested negative for latent TB infection prior to initiating therapy.
Risk of infection may be higher in patients greater than 65 years of age, pediatric patients, patients with co-morbid conditions and/or patients taking concomitant immunosuppressant therapy. In clinical trials, other serious infections observed in patients treated with REMICADE® included pneumonia, cellulitis, abscess, and skin ulceration.
Lymphoma and other malignancies, some fatal, have been reported in children and adolescent patients treated with TNF blockers, including REMICADE®. Approximately half of these cases were lymphomas, including Hodgkin's and non-Hodgkin's lymphoma. The other cases represented a variety of malignancies, including rare malignancies that are usually associated with immunosuppression and malignancies that are not usually observed in children and adolescents. The malignancies occurred after a median of 30 months after the first dose of therapy. Most of the patients were receiving concomitant immunosuppressants.
Postmarketing cases of hepatosplenic T-cell lymphoma, a rare type of T-cell lymphoma, have been reported in patients treated with TNF blockers, including REMICADE®. These cases have had a very aggressive disease course and have been fatal. All reported REMICADE® cases have occurred in patients with Crohn's disease or ulcerative colitis and the majority were in adolescent and young adult males. All of these patients had received treatment with azathioprine or 6-mercaptopurine concomitantly with REMICADE® at or prior to diagnosis. Carefully assess the risks and benefits of treatment with REMICADE®, especially in these patient types.
In clinical trials of all TNF inhibitors, more cases of lymphoma were observed compared with controls and the expected rate in the general population. However, patients with Crohn's disease, rheumatoid arthritis, or plaque psoriasis may be at higher risk for developing lymphoma. In clinical trials of some TNF inhibitors, including REMICADE®, more cases of other malignancies were observed compared with controls. The rate of these malignancies among patients treated with REMICADE® was similar to that expected in the general population whereas the rate in control patients was lower than expected. Cases of acute and chronic leukemia have been reported with postmarketing TNF-blocker use. As the potential role of TNF inhibitors in the development of malignancies is not known, caution should be exercised when considering treatment of patients with a current or a past history of malignancy or other risk factors such as chronic obstructive pulmonary disease (COPD).
Melanoma and Merkel cell carcinoma have been reported in patients treated with TNF-blocker therapy, including REMICADE®. Periodic skin examination is recommended for all patients, particularly those with risk factors for skin cancer.
REMICADE® is contraindicated in patients with moderate to severe (NYHA Class III/IV) congestive heart failure (CHF) at doses greater than 5 mg/kg. Higher mortality rates at the 10 mg/kg dose and higher rates of cardiovascular events at the 5 mg/kg dose have been observed in these patients. REMICADE® should be used with caution and only after consideration of other treatment options. Patients should be monitored closely. Discontinue REMICADE® if new or worsening CHF symptoms appear. REMICADE® should not be (re)administered to patients who have experienced a severe hypersensitivity reaction or to patients with hypersensitivity to murine proteins or other components of the product.
TNF inhibitors, including REMICADE®, have been associated with reactivation of hepatitis B virus (HBV) in patients who are chronic carriers. Some cases were fatal. Patients should be tested for HBV infection before initiating REMICADE®. For patients who test positive, consult a physician with expertise in the treatment of hepatitis B. Exercise caution when prescribing REMICADE® for patients identified as carriers of HBV and monitor closely for active HBV infection during and following termination of therapy with REMICADE®. Discontinue REMICADE® in patients who develop HBV reactivation and initiate antiviral therapy with appropriate supportive treatment. Exercise caution when considering resumption of REMICADE® and monitor patients closely.
Severe hepatic reactions, including acute liver failure, jaundice, hepatitis, and cholestasis have been reported rarely in patients receiving REMICADE® postmarketing. Some cases were fatal or required liver transplant. Aminotransferase elevations were not noted prior to discovery of liver injury in many cases. Patients with symptoms or signs of liver dysfunction should be evaluated for evidence of liver injury. If jaundice and/or marked liver enzyme elevations (eg, ≥5 times the upper limit of normal) develop, REMICADE® should be discontinued, and a thorough investigation of the abnormality should be undertaken.
Cases of leukopenia, neutropenia, thrombocytopenia, and pancytopenia (some fatal) have been reported. The causal relationship to REMICADE® therapy remains unclear. Exercise caution in patients who have ongoing or a history of significant hematologic abnormalities. Advise patients to seek immediate medical attention if they develop signs and symptoms of blood dyscrasias or infection. Consider discontinuation of REMICADE® in patients who develop significant hematologic abnormalities.
REMICADE® has been associated with hypersensitivity reactions that differ in their time of onset. Acute urticaria, dyspnea, and hypotension have occurred in association with infusions of REMICADE®. Serious infusion reactions including anaphylaxis were infrequent. Medications for the treatment of hypersensitivity reactions should be available.
TNF inhibitors, including REMICADE®, have been associated in rare cases with CNS manifestation of systemic vasculitis, seizure, and new onset or exacerbation of CNS demyelinating disorders, including multiple sclerosis and optic neuritis, and peripheral demyelinating disorders, including Guillain-Barré syndrome. Exercise caution when considering REMICADE® in patients with these disorders and consider discontinuation if these disorders develop.
Treatment with REMICADE® may result in the formation of autoantibodies and, rarely, in development of a lupus-like syndrome. Discontinue treatment if symptoms of a lupus-like syndrome develop.
In clinical trials, the most common REMICADE® adverse reactions occurring in >10% of patients included infections (eg, upper respiratory, sinusitis, and pharyngitis),
infusion-related reactions, headache, and abdominal pain.
Concomitant use of REMICADE® with anakinra, abatacept, tocilizumab, or other biologics used to treat the same conditions as REMICADE® is not recommended because of the possibility of an increased risk of infection. Care should be taken when switching from one biologic to another, since overlapping biological activity may further increase the risk of infection.
Live vaccines or therapeutic infectious agents should not be given with REMICADE® due to the possibility of clinical infections, including disseminated infections.
Bring pediatric patients up to date with all vaccinations prior to initiating REMICADE®. Exercise caution in the administration of live vaccines to infants born to female patients treated with REMICADE® during pregnancy.
For more information, please see full Prescribing Information and Medication Guide for REMICADE®. Provide the Medication Guide to your patients and encourage discussion. (Requires Adobe® Reader®. Click here to download.)References:
1. American Thoracic Society, Centers for Disease Control and Prevention. Targeted tuberculin testing and treatment of latent tuberculosis infection. Am J Respir Crit Care Med. 2000;161:S221-S247.
2. See latest Centers for Disease Control guidelines and recommendations for tuberculosis testing in immunocompromised patients.


text:
People want jobs. It really is that simple. Bloggers, editors, politicians and talking heads go on and on about who's got the answers to fix this economy. They scream and they yell, but at the end of the day people just want to be employed. They want a job where their skills are put to use.
Although I can't promise you I know what job is right for you, I can at least point you in the right direction. So here are 10 companies that are hiring employees this week:
1. Party City
Industry: Retail
Sample job titles: Payroll manager, assistant buyer/merchandising manager, IT project leader
2. Citi
Industry: Accounting, finance
Sample job titles: Project director, senior compliance analyst-AML
3. 24 Hour Fitness
Industry: Personal health
Sample job titles: Club manager, human resources generalist, personal trainer
4. AMC Entertainment
Industry: Customer service
Sample job titles: Manager, kitchen preparation
5. Children's Creative Learning Center
Industry: Education
Sample job titles: Marcom specialist, preschool teacher
6. Aarons Sales and Lease
Industry: Transportation and delivery
Sample job titles: Delivery driver, manager trainee, sales manager
7. Robert Half Legal
Industry: Legal
Sample job titles: Litigation paralegal, legal secretary, attorney
8. Bayer
Industry: Health care
Sample job titles: Manufacturing sciences manager – purification, neurology sales consultant
9. NurseCore
Industry: Marketing (various)
Sample job titles: Direct marketing process specialist
10. Technisource
Industry: IT
Sample job titles: Help desk, network engineer


text:
Rate Dr. Cordelia L. Sotelo
Dr. Cordelia L. Sotelo's Ratings
Dr. Sotelo is incredibly kind and easy to talk to. I would recommend her to anyone looking for an approachable and energetic primary care physician.
Was this rating useful? 0 [[ userState['ratings'][2236380].votes_count ]]
Was this rating useful? 0 [[ userState['ratings'][210934].votes_count ]]
Best experience I've had at a doctor's office in years. Easy to get an appointment, called me in right away, spent time with me. Just perfect!
Was this rating useful? 0 [[ userState['ratings'][210933].votes_count ]]
Dr. Sotelo is one of the most knowledgeable and caring doctors I've ever met. She listens and always makes me feel validated. She has a great sense of humor, and really tries to get to know her patients, rather than rushing us out the door. As long as she is within traveling distance, she will always be my family's PCP.
Was this rating useful? 0 [[ userState['ratings'][210932].votes_count ]]
Now goes by Dr. Sotelo, she is just fabulous. A good family practice and a caring doctor. It's been tough finding a good doc for my baby and I wish I could bring her here but we live too far, she's still my PCP and when we move closer, Dr. Lieberman-Sotelo will be my daughters doc as well.
Was this rating useful? 0 [[ userState['ratings'][210931].votes_count ]]
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text:
|Date Submitted:
|October 22, 2009, 7:57 pm GMT
|Last Updated:
|October 24, 2009, 4:29 am GMT
|Submitted By:
|scrachy74 (member since October 19, 2009)
|bart simpson
|bart simpson head with big eye ball
|3.0 mm
|11.0 mm
|Report Quality Rating:
|(4.65 stars, 15 votes)
|They got a well pressed logo that's for sure.
|Suspected Contents:
|User Report:
|I'll keep the report short. These are speed, they are NOT pipes. Good quality speed pills, try them if you like speed.
Enjoy and be safe.
|Alert Moderator
|Posted on October 22, 2009, 8:05 pm GMT by iluvspeed (member since October 19, 2009)
these are great speed pills, try them !
|Posted on October 22, 2009, 8:45 pm GMT by we r1 (Administrator)
|Posted on October 22, 2009, 8:47 pm GMT by zzyzx (member since September 2, 2008)
The bart simpsons head at notorious piperazines. Could you please provide us with a real picture
|Posted on October 22, 2009, 9:09 pm GMT by ocbudsmkr420 (member since August 13, 2009)
u got piped.
|Posted on October 22, 2009, 9:19 pm GMT by seeingrainbows (member since June 21, 2009)
The description of this sounds like a new bart simpson press. he says its round. So its not the cut-outs. And he also says its bart with BIG EYEBALLS. This does not sound the same as the other round barts that have been circulating. Maybe its a new press with new chems in it. However a real picture would be the best
|Posted on October 22, 2009, 10:32 pm GMT by savage951 (member since October 16, 2009)
hahah nice report?
|Posted on October 22, 2009, 11:04 pm GMT by speed4you (member since October 19, 2009)
One of the best speed pill ive seen in a while. Just one gave me pretty good rushes, gives you all the energy you need!
|Posted on October 23, 2009, 7:24 am GMT by seeingrainbows (member since June 21, 2009)
^^^^Speed4you Since u claim to have tried these maybe u can answer the the question. What did the stamp look like. Is it the same stamp as seen on all most round barts? If not how do they look different? Im very ingtrigued about a new bart stamp. I wouldnt trust it, buy it, or consume it but it may look pretty cool.
|Posted on October 23, 2009, 8:34 am GMT by ravenousblonde (member since October 1, 2005)
I second seeingrainbow's questions - a real pic of the pill would be preferred over this image. ~R*Mod
|Posted on October 23, 2009, 4:31 pm GMT by is0red2blue (member since January 3, 2009)
image here best i can with a webcam..
|Posted on October 23, 2009, 5:05 pm GMT by balootach (member since March 9, 2009)
do I have to remind people that we are in Quebec, pipes are quite "rare", and a WHITE ROUND bart pill is for me a good sing of speed pills. Still I didn't saw them for now, Im stuck with the apple's... btw stange logo... but hey, up in the brain speed is all the same!
|Posted on October 23, 2009, 6:44 pm GMT by sustanon (member since December 30, 2005)
Hahahha feel sorry for the dealer reporter. Well known pipes (:
|Posted on October 23, 2009, 7:21 pm GMT by tacos (member since February 28, 2009)
big white pill, quebec = SPEED. :D
|Posted on October 23, 2009, 8:13 pm GMT by balootach (member since March 9, 2009)
ocbudsmkr420 and sustanon, both of them are stupid child that doesn't read all the comments! And no, round bart aren't well known pipes, the bart head 3d yes!! READ!!!!
|Posted on October 23, 2009, 11:24 pm GMT by docteurlabeur (member since August 3, 2009)
I've pop one few second ago and...........HIGH CARAMBA
|Posted on October 24, 2009, 1:37 am GMT by ocbudsmkr420 (member since August 13, 2009)
u guys got speed pills in canada? that sucks, if u wannt get spun y dont u get a flute and smoke a big ol shard of ice? foggers from wall 2 wall, that dry smacking sound as u move ur mouth after blowing it out, fuckin ur chick for like 13 hours. now that is speed.
|Posted on October 24, 2009, 2:05 am GMT by balootach (member since March 9, 2009)
because 4 here meth is pure shit. gets you addict like no time and cause more damage to the body than amp.Really, meth suck, amp rulez!!
|Posted on October 24, 2009, 3:08 am GMT by we r1 (Administrator)
if you want some amp, go get an adderall script.
|Posted on October 24, 2009, 3:24 am GMT by sustanon (member since December 30, 2005)
I didnt say there pipes. i said i feel sorry for the guy who has a bunch of these and selling them as mdma. If u want speed then yeah buy shards or amphetamine sulphate.
|Posted on October 24, 2009, 4:36 am GMT by seeingrainbows (member since June 21, 2009)
Just as I suspected. A new bart simpson press. Too bad its speed n not the good ol' stuff. Altho i do understand some ppl enjoy the speed. To each their own. From what I read on here tho a lot of speed pills are created there. Maybe more popular than piperazines. The white tabs in particular. Its too bad these barts arent the good stuff bc that is a cool print.
And in response to the last comment^^^^sustanon:Hahahha feel sorry for the dealer reporter. Well known pipes (:
You did kinda say well known pipes. But i dont wanna be in the middle of that.
|Posted on October 24, 2009, 9:03 am GMT by ravenousblonde (member since October 1, 2005)
Ok people, stop dissing others for liking speed. As seeingrainbows said, to each their own. Remember, people who post speed pills here are doing us non-speed lovers a huge favor as these will probably be passed off as MDxx at some point. I don't see this as a dealer report, if it was, they wouldn't tell you it was speed.
This report should have 5 stars all the way - remember, you are rating the REPORT, not the pill. ~R*Mod
|Posted on October 26, 2009, 3:42 am GMT by hoes call me santa (member since June 16, 2009)
ocbudsmkr420, no offense, but you are fucking retarded.
Like who are you to tell others what to consume and what not? If people want to consume speed, they can, if you want to get addicted with meth, you also can.
If he wants to stay off highly addictive substances, it's his choice and I don't see why you would have a word to say.
|Posted on October 28, 2009, 4:01 am GMT by tacos (member since February 28, 2009)
where's higherlogic/spedfaster? did you taste them?
|Posted on November 9, 2009, 6:04 pm GMT by balootach (member since March 9, 2009)
from what ive heard, not that good, too weak... better go with the mush or any other one. Oh and btw, it's really rare here that dealers sells amp for MDxx, even tho it's easier to get speed rather than MDxx... Better buy a rock of pure MDMA, it's the real way to roll!
|Posted on November 11, 2009, 2:24 am GMT by subaruwrx (member since April 17, 2007)
lollll tweaaaaaaaaaaaaaaaaaaaaaaaaaaakerrrrrrrrrrrrrrrrrr
|Posted on November 17, 2009, 2:38 pm GMT by methamketamine (member since September 24, 2009)
I just try it, and word of truth consomation speed, take in a dozen and you'll see that it's Meth. and NOT the only Amphetamine, but specifically methamphetamine HCl. The crystalmeth crystal, the crystal is evil! ocbudsmkr420''whose''mentioned earlier. Tell you the information true friends you have not only the Internet to say anything!
methamphetamine HCl (meth'amfet'mēn ')
n brand name: Desoxyn Gradumet;
drug class: amphetamine (Controlled Substance Schedule II);
Action: increases release of norepinephrine and dopamine in cerebral cortex to reticular activating system;
Uses: exogenous obesity, minimal brain dysfunction, attention deficit hyperactivity disorder (ADHD).
Mosby's Dental Dictionary, 2nd edition. © 2008 Elsevier, Inc.. All rights reserved.
Pill Identification / Methamphetamine
|Posted on November 28, 2009, 10:04 pm GMT by wallrush (member since July 13, 2009)
WOOOOHOOOO!!! bART!!!!
|Posted on November 28, 2009, 10:09 pm GMT by wallrush (member since July 13, 2009)
stop descibig meth in other words than meth pleae :p
|Posted on November 28, 2009, 10:12 pm GMT by wallrush (member since July 13, 2009)
stop describing meth any other way than meth please sorry too fat for keyboard :p
|Posted on December 3, 2009, 10:45 am GMT by quadstaxx (member since November 9, 2009)
id like to take like 2 of these with some other pure pills would probably be a great mix haha
|Posted on December 5, 2009, 8:18 pm GMT by ramb0 (member since February 21, 2008)
same press as mine, im from quebec and these ARE THE BEST speed pills I have seen for a long time.. here ppl sells both Doves n BartSimpson or they sell Onstar.. For those who sell Dove n Barts I think Dove is a way to make money for the bart because it is so good. I tried both and Doves are so weak it takes me 1 1/2 to get high the morning before work and for bart I only take 1 and im awake and tweaked ahah I love this pill and im getting only those right now.
|Posted on April 23, 2010, 10:01 pm GMT by runforever (member since April 23, 2010)
Didn't like these. Speed isn't really for me though. I've only taken 1 though so maybe thats why. Lol
|Posted on September 2, 2010, 5:41 pm GMT by horrux (member since August 26, 2009)
Those were possibly the best speed I have ever taken. ramb0 you and me are alike. :)


text:
RSS 55 deals tagged "c'thulhu"
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Sponsored Deals
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Community Deals
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Pretty much, anyway. This is where you find the deals that wooters like you have ferreted out and brought to light. We're thinking it'll turn into a massive database of discounted products from around the Web, constantly expanding to absorb the newest deals from the very moment their prices are slashed, with each deal immediately rated by hordes of savvy voters to spotlight the very greatest deals in the world today. Hey, we can dream, right?
We use a fancy algorithm to determine which deals are catching the most buzz – they're under the Popular tab, which is the default view of this section. You can look for the most popular deals today, this week, or this month. The Fresh tab features the most recently submitted deals, so that's where to look for deals that everybody else doesn't know about yet. And the Search bar does what a Search bar does, only, uh, much wootier! Yeah! Right on!
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