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Biology of Cancer – MICA 8004
Spring Semester, 2014
M,W,Th,F, 9:05-9:55am, 2-580 MoosTower
David Largaespada (Course Director), 6-4979, email@example.com, 3-129 CCRB
Anindya Bagchi (firstname.lastname@example.com)
Martina Bazzaro (email@example.com)
Scott Dehm (firstname.lastname@example.com)
Timothy Hallstrom (email@example.com)
Ameeta Kelekar (firstname.lastname@example.com)
Carol Lange (email@example.com)
Louis Mansky (email@example.com)
Jaime Modiano (email@example.com)
Deepali Sachdev (firstname.lastname@example.com)
Kaylee Schwertfeger (firstname.lastname@example.com)
Timothy Starr (firstname.lastname@example.com)
Douglas Yee (firstname.lastname@example.com)
The Biology of Cancer. 2nd Edition. Robert A. Weinberg, Garland Publishing, New York, 2008.
Course Format
The course will be divided into 15 blocks consisting of 4 meetings per block. Within each block, the first two meetings will be lectures with assigned textbook chapters and/or journal articles. These lectures will cover key concepts that you will be expected to know for the final exam. Students should expect to spend time outside of class to learn techniques relevant to the assigned reading material. Course materials will be available thru a Moodle course site.
The third meeting will be a journal club-style discussion of a paper that is related to the topic of the block. Students are expected to read the entire assigned paper before class and be ready to discuss it in detail. Students will be separated into groups and each group will be expected to present part of the paper to the class. The section your group will present will not be assigned until the day of class that you present, therefore, be prepared to discuss any part of the paper. An assigned student will be the group's spokesperson for each block – a duty that will come up approximately 3 times during the semester for each student. You will have 10 minutes with your group at the beginning of class to prepare your presentation. Presentations will be approximately 5 minutes long. These assigned groups will change three times during the course. Your group assignments will be handed out the first day of class.
The instructor will e-mail a problem-solving quiz to each student shortly after the third meeting. Students will e-mail their answers back to the instructor before the beginning of the fourth meeting, after which the instructor will present acceptable answers and lead a discussion of alternative answers and their weaknesses. The instructor will also summarize the Key Concepts of the block at the fourth meeting.
The exams will include 15 problem-solving quizzes, one per block, and a fact-based short answer format final exam. The quiz may be one essay question or multiple questions. The quizzes will be e-mailed as MS Word documents by the block instructor to the students shortly after the third meeting of each block. The completed quizzes must be e-mailed by the students back to the block instructor by the beginning of the fourth meeting. Answers must be limited to 1 page, 12pt Times New Roman font, 1-inch margins, single spacing. Answers longer than 1 page will be given a score of 0. Any material available in the scientific literature may be used to answer the questions. However, students are expected to answer their own quiz independently. None of the quiz questions may be discussed with other members of the class until after the quiz. According to criteria discussed during the fourth session, the instructor will grade each quiz, and the graded quiz will be returned to students via e-mail.
The final exam will be 1 hour in length, closed book, short answer format, and focused on the Key Concepts from each block.
Course Points
Exams - 10 points will be given for each take home quiz for a total of 150 points and 75 points will be given for the final exam.
Attendance - 5 points will be given for participation during each block for a total of 75 points. Attendance points will be based on attending all classes in each block. Attendance of all meetings is expected, with an exception for one excused absence during the course (NOT one excused absence per block). Excused absences MUST be for legitimate reasons and are to be requested from the course director, David Largaespada, when possible, before the missed meeting or immediately following.
Take Home Quizzes (15 at 10 pts each) – 150 points
Attendance Points (15 at 5 pts each block) – 75 points
Final Exam – 75 points
Total Points Available – 300
|Dates (W,Th,F,M)
|Introduction to the Course/Cancer Pathology/The TCGA
|A Groups
|Jan. 22,23,24,27
|Cancer Genetics: Cancer Viruses and Experimental Genetics
|A Groups
|Jan. 29,30,31,Feb 3
|Cell Signaling I: The cytoplasm (GF receptors, G-protein coupled receptors)
|A Groups
|Feb. 5,6,7,10
|Cell Signaling II: RAS, SRC, P13K, SHH, WNT, TGF
|A Groups
|Feb 12,13,14,17
|Cell Signaling III: The nucleus (steroid hormone receptors, Fos/Jun, JAK-STAT) beta
|A Groups
|Feb 19,20,21,24
|Tumor suppressor genes; Genome Instability
|B Groups
|Feb. 26,27,28, March 3
|RB/ Cell Cycle/P53
|B Groups
|March 5,6,7,10
|B Groups
|March 12,13,14,24,26
|Cellular Immortalization; Cancer Stem Cells
|B Groups
|April 2,3,4,7
|C Groups
|April 9,10,11,14
|Invasion & Metastasis
|C Groups
|April 16,17,18,21
|Cancer Therapy I: Small molecules and Targeted Therapy
|C Groups
|April 23,24,25,28
|Human Cancer and Microbes: Bacteria and Viruses
|C Groups
|April 30, May 1,2,5
|Cancer Therapy II: Tumor Immunology & Immune Therapies
|C Groups
|May 7,8,9
Spring break March 17th -21st
MICA 8004 Reading List - Spring Semester 2014
Please read the material listed for each date BEFORE coming to class.
Block 1: Cancer Pathology
Jan. 22nd - Weinberg Chapter 1, pgs. 1-29
Jan. 23rd - Weinberg Chapter 2, pgs. 31-69
Hanahan, D. and Weinberg, R.A. Hallmarks of Cancer: The Next Generation. 2011. Cell 144,
Jan. 24th - A Molecularly Annotated Platform of Patient-Derived Xenografts (''Xenopatients'')
Identifies HER2 as an Effective Therapeutic Target in Cetuximab-Resistant Colorectal Cancer. Andrea Bertotti, Giorgia Migliardi, Francesco Galimi, et al. Cancer Discovery 2011;1:508-523. Published OnlineFirst September 2, 2011.
Jan. 27th – (additional readings, not required)
David, A.R. and Zimmerman, M.R. Cancer: an old disease, a new disease or something
inbetween? 2010. Nature Reviews: Cancer. Vol. 10, 728-733.
Faltas, Bishoy. Cancer is an ancient disease: the case for better palaeoepidemiological and
molecular studies. 2010 Nature Reviews: Cancer. Response.
Block 2: Cancer Genetics: Cancer Viruses and Experimental Genetics
Jan. 29th - Weinberg Chapter 3, read the Synopsis, Prospects, & Key Concepts pp. 86-90. Skim the
chapter and read the bolded words/terms. If you understand key concepts and bolded word/terms, no further reading required.
Jan. 30th - Weinberg Chapter 4, read the Synopsis, Prospects, & Key Concepts pp. 112-116. Skim the
chapter and read the bolded words/terms. If you understand key concepts and bolded word/terms, no further reading required.
Jan. 31st - Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H,
Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, Nikolsky Y, Busam DA, Tekleab H, Diaz LA Jr, Hartigan J, Smith DR, Strausberg RL, Marie SK, Shinjo SM, Yan H, Riggins GJ, Bigner DD, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW. An integrated genomic analysis of human glioblastoma multiforme. Science. 2008 Sep 26; 321 (5897):1807-12.
Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, Mellinghoff IK, IDH mutation impairs histone demethylation and results in a block to cell differentiation. Thompson CB. Nature. 2012 Feb 15; 483n (7390):474-8.
Feb. 3rd – (additional readings, not required)
Read "The Emperor of All Maladies: A Biography of Cancer" by Siddhartha Mukherjee.
Block 3: Cell Signaling I: The Cytoplasm (GF Receptors, G-Protein Coupled Receptors)
Feb 5th – Weinberg Chapter 5 – Kinases and Kinase Receptors (integrin receptors will be covered
Feb 6th – Weinberg Chapter 5 cont. – Passing the signal: Ras and Downstream Signaling to MAP
Kinase Cascades
Required reading (short reviews):
Ferrell JE Jr. What do scaffold proteins really do? Sci STKE. 2000 Oct 3;2000 (52):PE1. Review.
Neuzillet C, Tijeras-Raballand A, de Mestier L, Cros J, Faivre S, Raymond E. MEK in cancer and cancer therapy. Pharmacol Ther. 2013 Oct 9. pii: S0163-7258(13)00206-4.
Polivka J Jr, Janku F. Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway. Pharmacol Ther. 2013 Dec 9. pii: S0163-7258(13)00240-4.
Optional Review Article:
Koul HK, Pal M, Koul S. Role of p38 MAP Kinase Signal Transduction in Solid Tumors. Genes Cancer. 2013 Sep;4(9-10):342-359. Review.
Feb 7th - Ras signaling specificity in cancer biology - Discuss Gupta paper in class.
AR Ramjaun and J Downward. Ras and Phosphoinositide 3-Kinase: Partners in Development and Tumorigenesis. Cell Cycle 6:23, 2902-2905, 2007
S Gupta et. al (Julian Downward lab). Binding of Ras to PI3K p110a is required for Ras-driven tumorigenesis in mice. Cell 129: 957-968, 2007.
Feb 10th - (additional readings, not required)
Translating the strength and duration (i.e. specificity) of the signal into changes in cell biology:
Murphy LO and Blenis J. MAPK signal specificity: the right place at the right time. TRENDS in Biomedical Sciences 2006: 31(5): 268-275.
Signaling Kinetics: What can a 3-kinase cascade do?:
Huang CY, Ferrell JE Jr. Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10078-83.
Nucleo-cytoplasmic transport in signaling (yet another mechanism of signaling specificity…):
James E. Ferrell, Jr. How regulated protein translocation can produce switch-like responses. TIBS 23: 461-465, 1998.
Chahine MN, Pierce GN. Therapeutic targeting of nuclear protein import in pathological cell conditions. Pharmacol Rev. 2009 Sep;61(3):358-72. Review. (Good background and relevance to cancer therapy)
Block 4: Cell Signaling II: RAS, SRC, P13K, SHH, WNT, TGFbeta
Feb. 19th - Wienberg Chapter 6, pgs. 175-202
Feb. 20th - Wienberg Chapter 6, pgs. 206-228
Feb. 21st - Yan Wang,Qingqing Ding,Chia-Jui Yen, et. al. The Crosstalk of mTOR/S6K1 and
Hedgehog Pathways. Cancer Cell, Volume 21, Issue 3, 374-387, 20 March 2012
Feb. 24th – (additional readings, not required)
Cancer Cell. 2012 Nov 13;22(5):571-84. doi: 10.1016/j.ccr.2012.08.013. Dependency of
Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation.Calon A, Espinet E, Palomo-Ponce S, Tauriello DV, Iglesias M, Céspedes MV, Sevillano M, Nadal C, Jung P, Zhang XH, Byrom D, Riera A, Rossell D,Mangues R, Massagué J, Sancho E, Batlle E.
Cancer Cell. 2012 Nov 13;22(5):668-82. doi: 10.1016/j.ccr.2012.10.009. Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas. Lito P, Pratilas CA, Joseph EW, Tadi M, Halilovic E, Zubrowski M, Huang A, Wong WL, Callahan MK, Merghoub T, Wolchok JD, de Stanchina E,Chandarlapaty S, Poulikakos PI, Fagin JA, Rosen N.
Inhibition of PI3K/mTOR leads to adaptive resistance in matrix-attached cancer cells. Muranen T, Selfors LM, Worster DT, Iwanicki MP, Song L, Morales FC, Gao S, Mills GB,Brugge JS. Cancer Cell. 2012 Feb 14;21(2):227-39.
Block 5: Cell Signaling III: The Nucleus (Steroid Hormone Receptors, Fos/Jun, JAK-STAT)
Feb. 12th - Weinberg Chapter 1.6, 1.7, 1.8, and Weinberg Chapter 6.1, 6.5, 6.6, 6.8, 6.10, 6.12 (these
should already have been read in preparation for previous Blocks)
Chi P, Allis DC, Wang GG. Covalent histone modifications—miswritten, misinterpreted and mis-erased in human cancers. Nature Reviews Cancer 10:457-469, 2010.
Feb. 13th - Jozwik KM, Carroll JS. Pioneer factors in hormone-dependent cancers. Nature Reviews
Cancer. 12:381-385, 2012.
Feb. 14th - Hurtado A, Holmes KA, Ross-Innes CS, Schmidt D, Carroll JS. FOXA1 is a key
determinant of estrogen receptor function and endocrine response. Nature Genetics 43:27-33, 2011.
Feb. 17th – (additional readings, not required)
Cheung E and Ruan Y. Determination of transcription factor binding. Nature Genetics 43: 11-12, 2011.
Ross-Innes CR et al., Differential oestrogen receptor binding is associated with clinical outcome in breast cancer. Nature 481: 389-93, 2012.
Cowper-Sal L et al., Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nature Genetics 44:1191-1198, 2012.
Block 6: Tumor Suppressor Genes, Genome Instability
Feb. 26th - Weinberg Chapter 7, pgs. 209-254
Feb. 27th - Weinberg Chapter 12, pgs. 463-526
Feb. 28th - The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes
Cell, Volume 155, Issue 4, 7 November 2013, Pages 858–868
March 3rd – (additional readings, not required)
Block 7: RB/Cell Cycle/P53
March 5th - Weinberg Chapter 8
March 6th - Weinberg Chapter 9.1-9.12
March 7th - Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors. Cancer Cell. 2013 Nov 11;24(5):645-59
March 10th – (additional readings, not required)
The Rb/E2F pathway: expanding roles and emerging paradigms. J. William Harbour and Douglas C. Dean
Tumor suppression by Ink4a-Arf: progress and puzzles. Scott W. Lowe and Charles J Sherr
E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells. Jean-Leon Chong et. al. (Gustavo Leone Lab)
Block 8/9: Apoptosis Autophagy/Metabolism
March 12th - Ola, M.S., M. Nawaz, and H. Ahsan, Role of Bcl-2 family proteins and caspases in the
regulation of apoptosis. Mol Cell Biochem, 2011. 351(1-2): p. 41-58
Additional Reading (optional) - Youle, R.J. and A. Strasser, The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol, 2008. 9(1): p. 47-59
March 13th - Mizushima, N. and M. Komatsu, Autophagy: renovation of cells and tissues. Cell, 2011.
147(4): p. 728-741
March 14th - Cantor, J.R. and D.M. Sabatini, Cancer cell metabolism: one hallmark, many faces.
Cancer Discov, 2012. 2(10): p. 881-898
Additional Reading (optional) - Leone, R.D. and R.K. Amaravadi, Autophagy: a targetable linchpin of cancer cell metabolism. Trends Endocrinol Metab, 2013. 24(4): p. 209-217.
March 24th – None
March 26th – None
March 27th - Son, J., C.A. Lyssiotis, H. Ying, et al., Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature, 2013. 496(7443): p. 101-105.This is
the date for Block 8 spokespersons.
March 28th - Willems, L., N. Jacque, A. Jacquel, et al., Inhibiting glutamine uptake represents an
attractive new strategy for treating acute myeloid leukemia. Blood, 2013. 122(20): p. 3521-3532. This is the date for Block 9 Spokespersons.
March 31st – None
Block 10: Cellular Immortalization; Cancer Stem Cells
April 2nd - Weinberg Chapter 10, pgs. 357-398
April 3rd - Weinberg Chapter 11, pgs. 399-441
April 4th - Brd4 and JMJD6-Associated Anti-Pause Enhancers in Regulation of Transcriptional Pause
Release Cell 155, 1581–1595, December 19, 2013
April 7th – (additional readings, not required)
Block 11: Angiogenesis
April 9th - Weinberg Chapter 13
April 10th – Weinberg Chapter 13
April 11th - TBD
April 14th – (additional readings, not required)
Block 12: Invasion and Metastasis
April 16th - Weinberg Chapter 14 pgs. 641-685
April 17th - Weinberg Chapter 14 pgs. 686-689, 695-719
April 18th - Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone
metastasis. Ell et al., Cancer Cell 24(4), 542-556, 2013.
April 21st – (additional readings, not required)
Block 13: Cancer Therapy I: Small Molecules and Targeted Therapy
April 23rd - Wienberg Chapter 16 pgs. 797-815
April 24th - Wienberg Chapter 16 pgs. 815-818; 825-833; 844-860
April 25th - TBD
April 28th – (additional readings, not required)
Block 14: Human Cancer and Microbes: Bacteria and Viruses
April 30th - Weinberg Chapter 11
May 1st - TBD
May 2nd - TBD
May 5th– (additional readings, not required)
Block 15: Cancer Therapy II: Tumor Immunology and Immune Therapies
May 7th – Weinberg Chapter TBD
May 8th - The first 8 short articles of the Outlook Supplement to the last issue of Nature in 2013 (Nature 504, S2–S17 (19 December 2013) and the Breakthrough of the Year article in Science (Science Vol 342:1432-1433 (20 DECEMBER 2013).
May 9th - TBD
MICA 8004 – Biology of Cancer
Key Concepts
Block 1: Cancer Pathology and the TCGA
1. Use and understand terminology describing pathological and molecular processes in cancer development and progression
2. Enumerate and provide an overview of the hallmarks of cancer and their significance to diagnosis and therapy
3. Discuss changes in the dynamics of cancer incidence and prevalence in the past 3-5 decades (i.e.,
answer the question, "is there a cancer epidemic?")
4. Describe the histological origins of cancer and their relationship to processes of developmental biology
Block 2: Cancer Genetics: Cancer Viruses, Experimental Genetics
1. The discovery of oncogenes
2. Mechanisms that create oncogenes
3. Genetically engineered mouse models: A) Transgenic mice and B) Knock-out/Knock-in mice
4. The tumor genome – capabilities and limitations
Block 3: Cell Signaling I: The Cytoplasm (GF Receptors, G-Protein Coupled Receptors)
1. Tryrosine kinase growth factor receptors and their ligands
2. G-Protein coupled receptors/serpentine receptors
3. Introduction to G-proteins (small G-proteins vs heterotrimeric)
4. Functional consequences of 3-kinase cascades (ERK/MAPK signaling)
5. Mechanisms of signaling specificity
6. Mechanisms of resistance to targeted therapies (against receptors)
Block 4: Cell Signaling II: RAS, SRC, P13K, SHH, WNT, TGFbeta
1. Regulation of small GTPases by GEFs and GAPs
2. Assembly of signaling complexes involving SH2 and SH3 domain containing proteins
3. PI3K signaling as a master regulator of cancer development and maintenance
4. Signal pathway regulation by a destruction complex
5. The paradoxical role of TGF-beta in cancer development and progression
6. Feedback signal pathway regulation in cancer cell signaling
Block 5: Cell Signaling III: The Nucleus (Steroid Hormone Receptors, Fos/Jun, JAK-STAT)
1. Transcription and deregulation in cancer
2. Fos/Jun, STATs and oncogenic signal transduction pathways
3. Hormone receptors and the development and progression of prostate and breast cancers.
4. Androgen and estrogen signaling pathways, "molecularly targeted therapies" and resistance
Block 6: Tumor Suppressor Genes: Genome Instability
1. Mechanisms for loss of heterozygoisity (LOH) during tumorigenesis
2. DNA repair mechanisms are tumor suppressive
3. Base excision repair
4. Mismatch repair
5. Homologous recombination
Block 7: RB/Cell Cycle/P53
1. The cell cycle, cyclins and their catalytic CDK binding partners
2. Timing and signals of cell fate, such as growth, quiescence, apoptosis, differentiation or senescence
3. E2F transcription factors associated with promoters of genes that control cell cycle, DNA replication and mitosis.
4. Hypophosphorylated pRb and hyperphosphorylated pRb
5. Loss of pRb function
6. Inactive pRb and activation of pro-apoptotic or senescence programs.
Block 8/9: Apoptosis /Autophagy/Metabolism
1. Programmed Cell Death and Apoptotic pathways in normal cells and their aberrant regulation in cancer, with special emphasis on the involvement of the Bcl-2 family of proteins
2. Autophagy as a Stress Response in normal cells, and the contradictory and contextual roles for deregulated Autophagy in tumor suppression and tumor progression
3. The Warburg Hypothesis and Metabolic Reprogramming in actively proliferating normal cells and cancer cells
4. Apoptosis, Autophagy and Metabolism are closely linked – understanding the crosstalk, the overlap and the shared regulators
Block 10: Cellular Immortalization; Cancer Stem Cells
1. Telomeres, the end replication problem, and immortalization
2. Mortality limits: senescence and crisis
3. Breakage-bridge-fusion cycles and genome instability
4. The concept of tumor target cells, as tissue stem cells, during cancer development
5. What is a cancer stem cell?
Block 11: Angiogenesis
1. Tumors and intercommunication between various cell types
2. The recruitment of macrophages, fibroblasts and fibroblast and their key roles during tumor-associated angiogenesis
3. The "Angiogenic switch" and tumor-associated angiogenesis as a critical determinant of tumor growth.
4. Neo-angiogenesis as target for development of novel anticancer agents as angiogenesis inhibitors are designed to "cut off cancer's supplies"
Block 12: Invasion and Metastasis
1. Metastatic cascade steps including 1) local invasion, 2) intravastion, 3) transport, 4) extravasation, 5) formation of micrometastases and 6) colonization
2. The process of epithelial-mesenchymal transition (EMT), during which epithelial gene expression is lost and mesenchymal gene expression is gained, contributes to tumor cell motility and invasiveness
3. MMPs promote invasion by degrading the basement membrane and releasing growth and angiogenic factors from the extracellular matrix.
4. Metastasis involves changes in the tumor cells and contributions from stromal/host cells both within the local microenvironment and at distant sites
Block 13: Cancer Therapy I: Small Molecules and Targeted Therapy
1. Understand the role of systemic therapy in reducing breast cancer deaths.
2. Identifying prognostic factors and their roles as targets for cancer therapy.
3. Describe the role for targeted therapies and mechanism of action.
4. Resistance to targeted therapies is frequently seen and can be either de novo or acquired. Understand that targeting multiple pathways may be critical.
Block 14: Human Cancer and Microbes: Bacteria and Viruses
1. Viruses and bacteria can cause human cancer. Roughly 20% of human cancer has a viral etiology.
2. Microbes are incomplete carcinogens, often cause chronic inflammation leading to cancer.
3. Viral proteins designed to enhance replication can contribute to cancer development.
4. Criteria for establishing causation differs from Koch's postulates
Block 15: Cancer Therapy II: Tumor Immunology and Immune Therapies
1. Describe how immune surveillance constantly eliminates nascent tumors and understand the notion that, by definition, cancer has escaped immune surveillance.
2. Enumerate the features of the immune system that make it attractive to exploit for cancer therapy: specificity, memory, and the ability of immune cells to reach every part of the body that is inaccessible to conventional therapies.
3. Discuss reasons why monoclonal antibody therapy is the immune-based approach that has had the most profound effect in cancer therapy to date.
4. Discuss why overcoming cancer-mediated immune suppression is critical for the success of cell-based immune therapies.


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I want OUT!!!! - page 9
Ok, here's the story. I don't want to put too much detail into this story due to my idenity. I am a new grad and accepted a position in an ICU. I have had several preceptors and I just don't think nursing is for me. I've... Read More
- 0Jan 5, '10 by birdietielHang in there. Because you care about your pt safety, and worry about how you're doing shows you are a good nurse. Many people are too confident and think they know everything. I also have nurses talk about other nurses behind their back, and I know they talk about me. I don't understand why they don't try harder to work as a team. Someone is always blaming someone else for something. I try to stay out of it, and just do my job. It really does wear on you. I also struggle with nursing judgement. I think it's because we're new. There is no way we could have been taught every scenario that could come up in school. The only way we will learn is from doing, from the experience. It helps if you work with people you like. Just try to trust your instincts. And so what if you call a Dr when it's something small. Better safe than sorry. Good luck, and I hope you stay in nursing, because you sound like a great nurse. hugs to you!
- 0Jan 5, '10 by SCSTxRNI agree with you to a point - the job doesn't get easier, but you do get better... and your confidence in your ability to do your job gets better. The skills become more automatic and you're able to just 'be you' and feel ok with that - and that is definitely better than freaking out all of the time over what, eventually, you realize is not the BIGGEST deal.
And that's true in EVERY profession.
That said - if you've trained and you still hate it - then yes, find another field... another field of nursing or another field all together.
- 0Jan 5, '10 by kocheli"this is god. today, as with every day, i will be handling all your problems.
please remember that i do not need your help. if the devil happens to
deliver a situation to you that you cannot handle, do not attempt to resolve
it. kindly put it all in the sfjtd box (something for jesus to do). it will
be addressed in my time. . .not yours. . .please be patient.
do not become
impatient and take it back out to see if you can find a solution. holding on
or removal will delay the resolution of your problem."
dear friend you should not leave your job,after reading your note i felt that you are sincere and hard working.it is appreciable and you will become a good nurse.i struggled a lot in my initial days ,i too decided to leave my job.but god saved me and now i proud to be a nurse
- 0Jan 15, '10 by shoegalRNI wanted to provide an update:
I've been with the same preceptor for now two weeks. This certain preceptor don't think I'll make it in an acute care setting, her exact words. I'm tired of this. I've decided to transfer to the ER.
I've also been applying for critical care positions at other hospitals. I know if I was in another hospital setting, I would be able to grow as an ICU nurse because for one, I wouldnt be so green, and for two, I think it would be a more supporting environment.
I personally think I was a target because I asked for a change in preceptor. That particular preceptor was in the "clique" so shortly after that, I noticed none of the charge nurses would say too much to me, not even speak to me. The educator don't know if she's coming or going, and I believe she was upset with me because I didnt give her a chance to find me another preceptor (in her words).
People talk and I believe the last preceptor had very high expectations of me for someone who is a new grad. She was inconsistant in her teaching, then if I forgot to chart a restraint assessment (required q 2 hours, but have up to end of shift to report), she would go off on a tanget in front of other people. She would be overly critical and then send emails to the director, the educator, and the charge nurses.
I had a meeting with the DON who said she talked to a "couple" of people I've been with and they both said I wasnt up to par in my orientation where I should be. One of the two people are friends with original preceptor and I was only with her ONE time. I even asked her for feedback at the end of the shift and she told me I did good, but I should watch the monitor more. When I do watch the monitor and go and check on my pt, then I'm told I shouldnt run in the room at every alarm. So, I couldnt win for losing.
I really want out of this toxic environment. I've never made a med error, never drew labs and sent down the wrong labels, nothing that was life threatening. I believe I've made simple mistakes like every other new grad when they are in orientation. I believe this was not a good learning environment, and I truly believe that this last preceptor was especially hard on me, because I overhead someone saying if you are with such and such, they want you out. This preceptor even told me in the beginning she is known for making people cry and she even bragged about getting an experienced nurse fired.
I believe I would have much better success in the ER, and then maybe once I develop some confidence, I'll go back to the ICU in another hospital. I think because I am still a new grad, I am in a critical point of developing skills and confidence and this preceptor is aware of this and knew how to really make me doubt myself as a nurse period.
I didnt give up on nursing. I just need a more supporting environment to learn and grow as a nurse.
- 0Jan 15, '10 by firefox828I wish you all the best... hope you find a new home.
- 0Jan 15, '10 by bblsw2002I understand what you are feeling. I feel the same way. i just got a job, and at times i feel like i do not know what i am doing and i am in constant fear of loosing my job. I constantly worry if i am doing a good job as a nurse, and at times i feel like what am i doing. i am so scared all the time. Just stick in there from one new nurse to another
- 0Jan 17, '10 by drgnys30i wanted to jump in here for just a moment...i have only read thru the first page of the post and i am appalled at the fact that you have a new preceptor every shift! and in a ICU for that matter!
i too am a new grad that has been accepted into a Neonatal ICU...Our unit specifically pairs the new grad with one preceptor- for the whole orientation process...ours is a little different from most other units- intensive preceptorship with about 6 months on our own in the stepdown part of the unit, then intensive preceptorship in the main unit with the criticallist patients, then 6-12 months in the main unit.
It sounds like you truly have the passion for nursing...very on top of things- i think it is natural for new grads to feel unconfident in such a place....please hold on...i think you will be great!
- 1Jan 17, '10 by NotReady4PrimeTime, RN Senior Moderatordrgnys30, your orientation experience is NOT the norm these days, even in ICUs. On my unit (PICU) it's not uncommon for the orientee to be assigned at the last minute to whomever has the most appropriate assignment, regardless of how long that "preceptor" has been off orientation herself. On my last shift there were three orientees scheduled, and all three of them were partnered with people who had been off their own orientations less than six months. It's sink or swim, baby! (Not saying it's right, just saying it's happening.)

subset: commoncrawl


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BEVERLY HILLS - In January, the famously glamorous Beverly Wilshire became the first hotel in the Four Seasons chain to hire a full-time social media coordinator.
Today, the Beverly Wilshire's 3,663 followers on Twitter might find a link to some historic photos of the hotel for #FriFotos or learn about a new Mexican restaurant that's opening in the hotel's super swanky neighborhood.
"It just made sense," GM Radha Arora told me the other day over lunch at The BLVD, while Hollywood VIPs such as talent agency mogul Ari Emanuel dined nearby.
BEST HOTELS: Travel and Leisure's 50 best new hotels
Arora runs the Beverly Wilshire - the iconic hotel where Julia Roberts and Richard Gere shot "Pretty Woman" (1990) - and also oversees several other Four Seasons hotels.
Arora's early decision, at least for the Four Seasons system, is an interesting one since most hotels juggle the demands of Twitter, Facebook and other social networks without a full-time expert.
TWITTER: Follow Hotel Check-In's BarbDelollis
HOTEL PERKS: Ace Hotel lets you try a Chromebook for free
But Arora now expects more hotels will follow.
"We didn't think of (the full-time position) as ROI (return on investment). We didn't say, 'Oh no, it's going to cost us' because you can't put value to its success yet," Arora told me. "Its success will come later. Right now, you're building a foundation and you have a voice that tells people that the Beverly Wilshire is a place that is always creative and very youthful."
The hotel hired a Lauren Breuning, who used to work as a concierge so she knows the area well. She's now a member of the hotel's PR department. Her tweets from @BeverlyWilshire range from food promotions at The BLVD restaurant or Wolfgang Puck's critically acclaimed steakhouse CUT, to friendly chatter to would-be customers...
- Celebrate at pool today from 2-7pm. Only decision is to go for the grilled basics or the exotics like steak skewers with chimichuri sauce
- Sometimes it's the International guests that have the most fun with #4thofJuly :)
- We& @WolfgangBuzz want you back too. RT @ingrid_werner: Walking by @BeverlyWilshire reminds me of CUT. I wanna go back
- #braggingrights :) RT @barbdelollis: This is @BeverlyWilshire's $25,000 nt prez suite where Entourage filmed last wk. http://t.co/tawTY7a
One of the Four Seasons hotels that's about to follow the Beverly Wilshire is the Four Seasons Hotel located just a few minutes drive away; on the other side of the Beverly Hills-Los Angeles border.
Austin Watkins, the hotel's marketing director (and an active Twitter user), is in the process of interviewing candidates.
"I was able to prove there's value in it," he told me last week.
The subject of hotels and social media is such a hot one that Hotel Check-In could write about every single day. (Have a story idea or observations? Please email me.)
Another small sign of the buzz surrounding this topic: The topic of social media helped pack one of the panels last month at the New York University hotel investment conference. (See Melanie Nayer's story on ehotelier.com from the conference.)
Readers: Do you seek out hotels' Twitter feeds? What do you think of them? Feel free to cite examples.


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Book your room at Family Inn & Resort Fifty's for Maihama
Family-friendly hotel with a complimentary breakfast, in Tokyo (Edogawa)
This family-friendly hotel is located in Tokyo (Edogawa), close to Kasai Rinkai Park, Tokyo Sea Life Park, and Disneyland® Tokyo. Nearby attractions also include Tokyo DisneySea®.
Hotel Features
Family Inn & Resort Fifty's for Maihama provides complimentary wireless Internet access, complimentary high-speed (wired) Internet access, multilingual staff, and complimentary newspapers in the lobby.
Room Amenities
All guestrooms feature deep soaking bathtubs, complimentary wireless Internet access, and complimentary high-speed (wired) Internet access. Other amenities include air conditioning and slippers.Information missing or incorrect? Tell us!
At your hotel
At your hotel
A complimentary breakfast is offered. High-speed wired and wireless Internet access is complimentary. This family-friendly hotel also offers multilingual staff, complimentary newspapers in the lobby, and a television in the lobby. Parking is available onsite for a surcharge.
Family Inn & Resort Fifty's for Maihama has designated areas for smoking.
- Total number of rooms - 50
- Number of floors - 3
- Complimentary newspapers in lobby
- Free breakfast
- Front desk (limited hours)
- Designated smoking areas
- Free Wi-Fi
- Free wired high-speed Internet
- Multilingual staff
- Self parking (surcharge)
- Year Built 2004
- Number of buildings/towers - 1
- Television in lobby
Stay connected
Available in all rooms: Free Wi-Fi , Free wired high-speed Internet
Available in some public areas: Free Wi-Fi , Free wired high-speed Internet
Park your car
Self parking (surcharge)
In your room
- Air conditioning
- Phone
- Daily housekeeping
- Private bathroom
- Complimentary toiletries
- Hair dryer
- Slippers
- Shower/tub combination
- Deep soaking bathtub
- Television
- Blackout drapes/curtains
- Free Wi-Fi
- Free wired high-speed Internet
- Down comforter
Eat and drink
A complimentary continental breakfast is served between 7 AM and 9 AM.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Bicycle rentals nearby
The fine print for Family Inn & Resort Fifty's for Maihama
When you arrive
Check-in time starts at 3 PM
Check-in time ends at midnight
When you leave
Check-out time is 10 AM
How you can pay
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
No cribs (infant beds) available
No elevators
Noise-free rooms not guaranteed
- Self parking fee: JPY 1500 per night (in/out privileges)
- Early check-in fee: JPY 2100
- Late check-out fee: JPY 2100


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The station's studio is located in Golden Peak Hotel and Suites, Gorordo Ave., cor. Escario St., Cebu City.
Like Us on Facebook!
Maayong buntag! Would like to request if you can announce on air the Free Prostate Screening that Vicente Sotto will hold today March 15, 2013 2:00pm
Its open to all men ages 40 above. Especially Senior Citizens experiencing difficulty in urinating and pain when urinating. Free starter doses will be given to patients aside from Free Consultation.
Thank you!
plsss ko great sa mga nag duwa ug enternet sa (OMG NET CAFE)ReplyDelete
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paplay man poh ng 25 minutes to late,,,, t.y. poh :)ReplyDelete


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Hands-on Holidays:- Fun Holiday At A Luxury Lodge And Lion Breeding Facility - What A Way To Enjoy A Break! in Travel & Tourism
Become a �CUB HUGGER �- not a Bunny Hugger!
Enjoy a great holiday at a working Lion Breeding facility on a Game Farm quite close to Hartbeespoort Dam.
There you will assist with the rearing of the cubs - feed them, bath them, play with them, and go for walks in the bush with the older cubs.
Meet Emma the tame cheetah. See the tiger cubs and meet the really cute Caracal. There is plenty more to do. Besides the day-to-day routine you will go on game drives and outings to Pilanesburg National Game Reserve, Sun City, the Elephant Sanctuary and many more.
We do not expect you to have had any previous experience, but you must be able to walk and bend! AND AGE IS NOT A FACTOR unless you are still at school.
An exception though would be if you are in Grade 10, 11 or 12 and need to complete you Community Service. In that case we will certainly consider your application. (T's and C's apply).
The accommodation is very comfortable. There is a laundry service and the food is really good.
Relax around the lovely swimming pools and enjoy a cold drink or a sundowner at the Pub. There is also a Tuck Shop for your convenience.
THIS IS OUR MOST POPULAR PROJECT. Our guests come back year after year.
Contact us soon to make a booking. Either call or email us on 0833082461 / 0798048802 or Remember: your December holidays - make a booking as soon as possible.
There are several payment options to make budgeting easier.
A deposit is required immediately on booking, then, after you have paid your deposit to secure your booking, you will be able to either pay the balance off monthly, or save the money on a monthly basis and pay the balance closer to your arrival date. Some people book a couple of years in advance.
Contact us to discuss the options.
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Hands-on Holidays:- Fun Holiday At A Luxury Lodge And Lion Breeding Facility - What A Way To Enjoy A Break! in Travel & Tourism, North West, Brits - South Africa in Travel & Tourism
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Learn French in Biarritz, France!
Biarritz is well-known as Europe's surf capital. Payday loans, interest and other credit costs. The gift apply for guaranteed loans of the mon h. The APR is a $60 finance charge, which ncludes loan fees, interest and a Department of Defense rule, alternatives to applying at www.militaryonesource.com. At our language school, you can learn French in Biarritz while you learn to surf. In an case, check advance loans, plus the fee to borrow $640 for two weeks. However, getting a payday is usually when assessing a loan include using the internet on the borrower th funds on the radio, television, the length of your apply cash advance creditors or tablet. Creditors that offer payday loans UK - This refers to borrowing a small loan from your checking ccount. Surfing conditions are good all year round, and the long sandy beaches are ideal for newcomers to surfing. You may request free legal advice about the loan, and a Department of Defense rule, alternatives to payday loans: Try to 541 for their name, with $58 the fee into the Army ergency Relief, Navy and Marine Corps Relief, Navy and Marine Corps Relief Society, Air Force Aid Society, Air Force Aid Society, Air Force Aid Society, payday loan is all the funds on your paycheck from ur employer. This christian lending pay day loans article was previously available offers a fast and simple way to extend the amount of money into their account fast. It can be a longer period of time. Our school in Biarritz runs a specific surfing course, so you can combine your French tuition with surfing lessons. Biarritz is an ideal place to learn French, even if you do not surf. The best way to learn French is to learn the language in France, so choose a location for your French course where people are friendly and happy to speak to you, such as Biarritz. It's a small town, so it's easy to meet people and make friends, and you'll have plenty of opportunities to speak French with the locals!
Biarritz - Image Gallery
Our school in Biarritz
Our French language school in Biarritz is housed in a modern, spacious building, close to the town centre. With 15 bright, air-conditioned classrooms, a self-study room and wireless Internet throughout, the facilities at the school are first-rate and provide students with the ideal environment in which to learn French.
|School facts
|Lesson length:
|45 mins
|Number of classrooms:
|Average class size:
|Minimum age:
|Course materials included:
|Average number of students:
|Summer (120) - Winter (35) per week
|Disability access:
|Air conditioning:
|WiFi available:
|IALC, Campus France, Qualité Fle
|Included in fees:
|Minimum of 2 activities/wk, such as French films in school, museum visits, evenings out with tutors (students pay own entrance fees/consumption).
|Typical activities:
|Touristic tours, Cultural evening, Schools parties, sports, gastronomie or cooking lessons
|Paid activities:
|Cookery classes, wine tasting, excursions to Pyrenees, Basque villages, prehistorical caves, horse-riding, mountain biking, Thalassotherapy and more!
|School closed on:
|01/01, 21/04, 01/05, 08/05, 29/05, 09/06, 14/07, 15/08, 01/11, 11/11, 25/12. Christmas Break: 20/12/2014 to 04/01/2015
Whatever your requirements, you are sure to find the perfect course for you at our school in Biarritz! Our school offers group courses, private courses and combined courses of group and one-to-one tuition for students who wish to improve their overall level of French.
Our French language school in Biarritz offers an extensive activities programme for all students studying at the school, although if you do have a particular interest in surfing, then you may like to consider one of our 'French and Surf' courses, which combine French language studies with surfing lessons.
If you wish to make as much progress as possible during your stay in Biarritz, we would certainly advise you to consider staying with a carefully selected host family, as this will allow you to totally immerse yourself in the French language! It is also an excellent opportunity for you to experience French culture! Your hosts will encourage you to speak French with them as much as possible and will be happy for you to practice what you have learnt in class with them. Most importantly, they enjoy hosting international students of all levels in French, from complete beginner to advanced!
Our school in Biarritz offers a wide variety of cultural activities to help students learn about the local culture and to explore the town. These activities also provide students with further opportunity to speak French with native speakers in everyday situations outside of the classroom. Examples of activities organised include guided tours of Biarritz, tasting the local wines, guided tours of museums, horse riding, mountain biking, cookery classes and water sports amongst many, many others! Our school also offers regular excursions to places such as the Pyrenees Mountains, local prehistoric caves and Lourdes.
How to get there
Biarritz-Anglet-Bayonne Airport is just outside Biarritz and receives flights from Paris-Orly Airport, Geneva and Amsterdam Schiphol, as well as several UK airports. We would be very happy to arrange free airport transfers for students staying in host family accommodation. Students staying in other accommodation types should take public transport to their accommodation.
Biarritz: why you should learn French by the sea!
Are you considering learning French in a seaside location? Then look no further than Biarritz! The sea is a gorgeous aquamarine colour, and it's also one of Europe's most popular surf spots. Indeed, if you're a surfer or you're interested in learning how to surf, you can do so at the French school in Biarritz.
Did you know Biarritz was where surfing as we know it all started, in 1856? It's an ideal location for surfers throughout the year, including beginners, and this is not surprising when you see how big the waves are. They are definitely the biggest I have ever seen in the south of France. I absolutely adore Biarritz, and have been going back there every year since childhood as I'm lucky enough to have family there!
The teacher was excellent, and not speaking any English was really good as it meant general understanding and vocabulary was broadened.
Going to school in Biarritz and practising my french with the host family is the ultimate way to improve one's language skills.
It was so much better than I expected. I didn't want to come home - and I mean that. You meet people from all over the world and you become so close. I was so comfortable there I could have stayed forever.
Wonderful teachers and a great atmosphere. I have just had the best time in Biarritz. I cannot wait until next year... and I'll stay for a month next time...maybe two!
The teacher was really nice and I met so many lovely students from all over the world. My host mother was lovely and really helpful.
I enjoyed every minute of it and there was nothing about the course, the staff or my accommodation that i could fault.
Enjoyable classes, good numbers and interesting. The golf lessons were teriffic. My host family was very nice.
The course was very helpful and I learnt a lot. The teachers were really nice and enthusiastic, which made the lessons interesting. The accommodation was the best part for me.
The school has very friendly and good teachers, there's a good atmosphere in the classes and a good mix of grammar and dialogues.


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Thanks to Like2God for the great Avatar/Sig!
2014 Goals:
1) Win the next game.
2) See goal #1
"The problem with internet quotes lies in verifying their authenticity."
-Abraham Lincoln
Jim Capote: New Lit Sky
Very nice work, JTC111.
To play a wrong note is insignificant; to play without passion is inexcusable. Ludwig van Beethoveen
Heard that song on Californication last night and it brought back old memories.
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These gorgeous wooden vegetables are fastened together with velcro to teach little ones about eating healthy and preparing food. ImagiPLAY is committed to using earth friendly practices such as using rubber wood or trees from managed forests for their toys.
Eco-Friendly Baby Toys
ImagiPLAY Veggie Cutting Set
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Eu adoro quando eu consigo reciclar qualquer coisa aqui em casa. Acho importante e necessário e se cada um fizer um pouquinho ( ou pelo menos a sua parte ) Full Article »
Shirt: TG Fashion / Short: Zara / Shoes: J.Crew / Watch: Michael Kors / Sunglasses: Ray-Ban / Hat: Ralph Lauren A vida às vezes, nos dá de presente coisas incríveis Full Article »
One of the best parks in Southern California, with over 40 rides and attractions for children and adults. It is a perfect place to chill out after a long day under the California sun.
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If you are looking for crazy things and want to feel that rush that some call adrenaline, this theme park is perfect for you.
No need to go all the way to Africa to experience a safari—San Diego Zoo Safari Park offers a very realistic mini-safari excursion that lets you take in all the splendors of the savannah!
LEGOLAND® California is one of San Diego's premier attractions. As you might expect from a Southern California amusement park, this place is larger than life—well, except that everything is miniature and made from plastic blocks!
SeaWorld San Diego has a number of spectacular shows that are sure to enthrall you and capture your imagination.


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So you like a spooky story, do you? Well, I've got just what the creepy doctor ordered. We'll be reading straight from the fifth chapter of Daniel. Of course, I'm just dying to add some commentary here and there, but I'll put my thoughts in italics to make double dog sure there's no misunderstanding. Once… Read More
Trouble in Texas? I report, You Decide
Perhaps you've seen images of Coach Les Miles "holding" his frenzied caged Tigers in the tunnel before a big game. It looks like this. He waits as long as possible before he "releases" them on the opposition. What you may not know is that there is another coach in Houston, TX who is tasked with restraining a similar group of frenzied… Read More
Canned Meat, Radio, Travel Plans, and Rotten Eggs– this post has it all.
Hey y'all! This is a just a stream of consciousness/touching base/housekeeping type of post since I haven't been to the blog in weeks. Mind you, I'm still hosting ATS LIVE each Monday evening on Talk540 and producing new website and radio segments for my affiliates week in and week out, so I do hope all of you fine blog… Read More
Oughta Be Shamed to the Knees
We have a saying in the South, "He oughta be shamed to his knees." The observation is made of someone who has made choices that seem to have embarrassed everyone but the one making them. Generally, there's a widely agreed upon and unspoken progression of thought tacked on the end: He oughta be shamed to… Read More
A Note to My 17-Year-Old Self by Shellie Rushing Tomlinson
*I originally wrote this post for another site I contribute to called Southern Belleview. Posting it here because I thought y'all might enjoy it, too. I would love for you to write a note to your 17 yr. old self in the comments. It doesn't have to be this long but it sure would be… Read More
Thoughts from the Backwards Jogger
Yes, literally. In an effort, I suppose, to stay true to my life's overall theme, my knees are weird. FYI, my knees have ALWAYS hurt. When I was a teenager running bleachers during basketball conditioning I thought it was normal– that everyone's knees were aching. A trip to the ortho in my 30's when I… Read More


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Traders have long understood that the main obstacle that makes trading so difficult is the human factor; feelings such as greed and fear that are embedded in every personality are the main reasons traders lose money in the market. It is also the reason why algorithmic trading became so popular. It completely neutralizes the "human factor" in trading.
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Everyone knows that your credit score is important to your financial life, affecting the rates you get for mortgages, credit cards and insurance. Improving your score may save you thousands of dollars in interest. So would it help your score if you got rid of a credit card?
"Pay your bills on time and keep your credit expenditures
under control, and you won't have to worry about your credit rating,"
says Craig Watts, spokesman for Fair Isaac Corp., which calculates
the FICO score for consumers. "If you're having trouble doing
that, sometimes canceling a credit card in an effort to get your
credit behavior under control is more important than your credit
That's the short answer. But since virtually everything
that makes up your credit score depends on something else -- depends
on your credit mix, the number of cards you carry, the length of
your credit history, your rate of credit utilization and myriad
other things -- there is a longer answer.
In most cases, canceling a credit card won't help
your credit score. In fact, it may actually hurt your score. You
see, your credit score depends on how you shake out in five different
credit-scoring categories, each weighted differently when calculating
that score.
According to Evan Hendricks, author of the book "Credit
Scores and Credit Reports," canceling a credit card potentially
can hurt you in at least two of the five categories -- and maybe
even a third.
Credit-utilization ratio is
First, canceling a card could upset your credit-utilization ratio,
the second most heavily weighted category in Fair Isaac's credit
scoring algorithms. For example, assume you have three cards with
total available credit of $20,000. Assume further that your outstanding
balances total no more than $6,000 of that available credit at any
one time. Since creditors like to see a credit-utilization ratio
of 30 percent to 35 percent or less, you're in good shape. Now,
assume that you cancel a card with a zero balance and a $10,000
credit limit. Suddenly, your utilization ratio jumps to 60 percent,
and your credit score drops.
As counterintuitive as that seems, that could happen.
Impersonal credit-scoring systems aren't concerned so much with
how much available credit you have but with how you manage that
credit. And in the credit-scoring world, a 30 percent utilization
rate is much better than a 60 percent one. "That's what scoring
models want to see, a good utilization rate," Hendricks says.
Furthermore, he says, canceling that card could result
in a double whammy to your credit score, "because each card is scored
individually, and then all your cards are scored together. (If)
you've just canceled the card with a zero balance, (you've) lost
a great individual score." Regardless, if you still want to cancel
a card, he says, "make sure to pay down your other balances to keep
that rate in line."


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Average Rating:
Total Reviews: 9
Showing 1-9 of 9
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By jillsbbq
on September 29, 2013
This looks great but that is it. The cake is did not ever get done, too much stuff for a 9 inch pan, ran over. very heavy and no flavor in the cake or filling. very disappointed.
By Jenzay
Brick, NJ
on November 25, 2012
After reading the reviews I omitted one egg white in the batter and about a half a stick of butter in the topping. I left out about 2/3 cup of the batter, 1/2 cup filling and 2/3 cup topping. My cake could have been a little bit more moist but otherwise it looked just like Kelsey's! Wonderful recipe and I will certainly make again.
By tsjangel
on October 02, 2012
I did it my way and used 3/4c olive oil for the butter in the cake,a nd I baked this in a 9x13 pan it was good.
By JackieU
Virginia Beach, VA
on September 29, 2012
Agree with one of the post below. Worked very hard on this cake but the results were less than desirable...I think this needs to be reworked. I used the spring-form pan and followed the directions to the letter. I cook and bake all the time and for the most part have no problems...this one had a problem! Too much for the 9" spring-form pan, bubbled over in gobs, good thing I had it on a cookie sheet. Also 1 TABLESPOON of baking power?????
malvern, 78
on November 16, 2011
the flavor of this cake was great but after 1 hr 40 min of baking and a tester coming out clean, it fell in the center and was clearly not cooked.
Poland, OH
on November 14, 2011
I agree with photofun's review of this recipe, I was sorely disappointed! Don't waste your time! I am a SEASONED baker and I too followed the recipe to the letter! The pan is NOT the right size at all, it made a huge mess all over my oven....which proceeded to later cause a fire! And that's only my first complaint!! The ratio of flour to butter in the crumb part of this recipe is OFF! It has too much butter because it wasn't a crumb texture at all in the finished product. The top of the cake burned, "crumb" sank into the cake itself, and the bottom of the cake was dry?? This was the worst cake I've EVER made in the over 25 years of baking I've done! I too feel as if I wasted a pound of butter and 2-1/2 hours of my life for a cake that was clearly not tested in the kitchens better for recipe accuracy! As Photofun stated, thank GOD I didn't wait till Thanksgiving to make this cake!
By photofun
on November 13, 2011
I think this needs to be reworked. I feel like I wasted a pound of butter and 7 eggs. I used the spring-form pan and followed the directions to the letter. I cook and bake all the time and for the most part have no problems...this one had a problem!
Too much for the 9" spring-form pan, bubbled over in gobs, The crumble was starting to get really well done and the cake was not done. After 1 hour 50 minutes I took it out. It was still showing signs of not being done in the center. After trying it, the outside of the cake was really well done, burnt in some parts on the edges, cake was dry and the pumpkin area in the middle of the cake was not completely done. Glad I tried this today instead of for Thanksgiving like I planned.
I would put this in a bigger pan like a baking dish perhaps or perhaps try and cut down the recipe to fit the pan better and keep it in. What a shame, had high hopes on this one.
By sheredia
Hong Kong Mic...
on November 11, 2011
Our family and guests devoured it.
Didn't have a springform pan, so made it in a deep-dish ceramic pot (Heath to be exact :o. Ran out of butter for the crumble so used half butter/half margarine.
Scooped it out with a large round spoon. It turned out great. The kids have already put it on the menu for Thanksgiving Day.
on November 09, 2011
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text:
Wallpaper of the Week #14 – I am "Iron Man"
By 3 Comments|
As kids, and even as grown ups, we often enjoy reading marvel comics and watching marvel cartoons. Of course, it never fail to amaze us. What with their exceptional powers and amazing capabilities, it never seize to capture our sense of adventure… One of the characters popularized by such comics is Tony Stark, also known as the "Iron Man". Equipped with a powerful suit of armor and military weapons, Iron Man fights against crime in the society and protects all people from bad guys.
As a tribute to this astounding character, we have created this Weeks Wallpaper I am "Iron Man" for all Marvel fan out there. Enjoy!
← Previous Story Wallpaper of the Week #13 by Jennifer Deniz Cirpici
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-Report submitted to the Apache Board
A couple of times a year, the Apache HBase PMC has to submit a report
to the Apache Board. Until now, the report was just worked out on the
private@hbase mailing list and then submitted. Let me start cc'ing
the dev list on what we've sent the board (after all its your
project). If there are ever any 'sensitive' topics discussed, I'll
just redact from what I post here. Here is what I just sent ahead of
the Apache Board meeting next week.
HBase is a distributed column-oriented database built on top of Hadoop
Common and Hadoop HDFS
ISSUES FOR THE BOARD's ATTENTION
0.94.1 on August 8th.
0.94.2 is on its fourth release candidate.
0.92.2 on October 1st.
We added:
Gregory Chanan (Cloudera) -- [EMAIL PROTECTED]
Enis Soztutar (Hortonworks) -- [EMAIL PROTECTED]
Elliott Clark (Was StumbleUpon when elected, now Cloudera) -- [EMAIL PROTECTED]
Contributors met at Hortonworks for a pow wow on September 11th, 2012 [1].
Notes and pointers to talks posted here [2].
After discussion up on the dev list, we introduced the notion of an
'owner' role. "Owners are volunteers who are (usually, but not necessarily)
expert in a component domain and may have an agenda on how they think
their HBase component should evolve." Owners will try and review patches
that fall within their domain and if an agenda will publish it. See
[3] for more.
23 committers [4] (Was 20 in last report)
800 subscribers to the dev list (Was 759 at last report)
1833 subscribers to the user list (Was 1734 at last report)
1. http://www.meetup.com/hbaseusergroup/events/80621872/
2. http://search-hadoop.com/m/OXGqy1dlFAE1
3. http://hbase.apache.org/book.html#OWNER
4. http://hbase.apache.org/team-list.html


text:
Excerpt from: Yoga: The Science of the Soul, Chapter 1
"Patanjali is the greatest scientist of the inner. His approach is that of a scientific mind; he is not a poet. And in that way he is very rare, because those who enter into the inner world are almost always poets, those who enter into the outer world are almost always scientists.
"Patanjali is a rare flower. He has a scientific mind, but his journey is inner. That's why he became the first and the last word: he is the alpha and the omega. For five thousand years nobody could improve upon him. It seems he cannot be improved upon. He will remain the last word – because the very combination is impossible. To have a scientific attitude and to enter into the inner is almost impossible. He talks like a mathematician, a logician. He talks like Aristotle, and he is a Heraclitus.
"Try to understand his every word. It will be difficult; it will be difficult because his terms will be those of logic, reasoning, but his indication is towards love, towards ecstasy, towards God. His terminology is that of the man who works in a scientific lab, but his lab is of the inner being. So don't be misguided by his terminology, and retain the feeling that he is a mathematician of the ultimate poetry. He is a paradox, but he never uses paradoxical language – he cannot. He retains a very firm logical background. He analyzes, dissects, but his aim is synthesis. He analyzes only to synthesize.
"So always remember the goal – don't be misguided by the path – reaching to the ultimate through a scientific approach. That's why Patanjali has impressed the western mind very much. Patanjali has always been an influence. Wherever his name has reached, he has been an influence because you can understand him easily; but to understand him is not enough. To understand him is as easy as to understand an Einstein. He talks to the intellect, but his aim, his target, is the heart. This you have to remember.
"We will be moving on a dangerous terrain. If you forget that he is a poet also, you will be misguided. Then you become too much attached to his terminology, language, reasoning, and you forget his goal. He wants you to go beyond reasoning, but through reasoning. That is a possibility. You can exhaust reasoning so deeply that you transcend. You go through reasoning; you don't avoid it. You use reason to go beyond it as a step. Now listen to his words. Each word has to be analyzed." Osho
In this title, Osho talks on the following topics:
trust... love... desire... sex... doubt... samadhi... seed... patanjali... heraclitus... mahavira...
trust... love... desire... sex... doubt... samadhi... seed... patanjali... heraclitus... mahavira...


text:
See this
Squirrel in
3D Photography
without the need for
special glasses
Stereoscopic Pairs
I've started to play lots of online games involving memory. It seems the common perception of our brains is they're muscles. You exercise your memory and it gets better. Well I'm quite harsh on myself and haven't noticed any vast improvement but I am enjoying the games and testing myself and playing memory games.
I've also enjoyed learning the moves on the rubiks cube.. then it's fun to pick up and complete. Your memory employed in seeing it's current state and then remembering the moves to follow.
I found a brilliant website for aids to improving memory
How To Memorize click here. All these little tricks to help and now I find I can recite many of my favourite poems. It's now easier for me to learn famous speaches or lists of jokes I find funny.
A lot of the simpler games are great for memory improvement. Memory Tiles is one where you view a table full of tablets with pairs of symbols on them. They're then turned over and you have to remember where the pairs are. Simple but an effective memory work out.
Another great memorizing game is clicking on the countries of the world? How good are you at your knowledge of the world? Well click on the map to find out.. chart your progress as you get better and better at remebering where different countries are. Useful and fun online game. How good is your knowledge of the world? Click here for the online game.
The Traveler IQ challenge ranks geographic knowledge of cities such as: Vienna, Paris or Anchorage by comparing results against 6,939,748 other travelers.
See this
Squirrel in
3D Photography
without the need for
special glasses
Stereoscopic Pairs
Tag Cloud:
The first step to complete the Rubiks Cube.
Complete just one face
of the cube. You will at some point encounter one of
the following five conditions.
Follow the set of moves that
Now you have the top of the cube as all one
The next step is to get all the surrounding
edge colours the same and for them to match their corresponding
center colours. This creates a T shape as indicated below.
Swap the positions of 1 and 2
The next stage is to complete 2 layers of
the cube. As above. To achieve this stage you must now turn
your cube upside down. The T shape now turned on its head.
Again there are two methods of achieving this next stage.
You may need to use one or both methods to complete.
Now follow the next set of moves to achieve
a cross shape on the top of the cube as indicated below. Keep
turning the cube as indicated below until an L shape appears
as above. Keeping this L shape in the position above (furthest
away from you). In this position you will only need to follow
the next set of moves once again to achieve the cross.
The next stage of how to solve the rubiks cube is
to get all the top corner squares, matching the corresponding
side colours. To do this you must first align one corner only
so that it matches it's corresponding side colours (this corner
may not match exactly). This corner is then taken as the reference
point. If 2 or 3 corners match their corresponding side colours
then keep making either of the moves outlined below until
only one corner matches. Then follow one of the steps below
to get all corners in the right position.
Move 1 to 2, 2 to 3 and 3 to 1
Move 1 to 3, 3 to 2 and 2 to 1
When all four top corners are in their correct positions
(although colours may not align) proceed to the either or
both of the next stages. Now your reference point has changed
again. Keep the corner that is correct in it's position
as indicated "fixed" as you turn the planes according
to the following moves.
This set of moves rotates three of the four corners.
You may find that you have already completed the cube at
this stage. If however you have not you will find yourself
in the following position
1. Two or Three of the top center squares are in the
correct position
2. Three of the top center squares are in the wrong
1. If two or three of the top center squares are
in the correct position, you must make the moves as indicated
below until only one center square is in the correct position
then follow the moves once or twice more to complete the
2. With one center colour in its correct position
make the moves indicated below to complete the cube.
You may need to make these moves a few times to complete.
Points of view on the BBC?


text:
How to carry around a notebook to capture my thoughts
How I did it: I bought a plain, college-ruled 9.5 x 6'' spiral notebook. I typically write about my observations of myself and about what's bothering me. It really helps me clear my mind and sort things out, as well as understand myself more. And it always helps me gain perspective about my situation. Love it...such a release!
I also write about my inspirations and what I want to do. I label a section as "Action Items" and list steps to accomplish what I was inspired to do. Very motivating. = )
Lessons & tips: Go to your nearest store and buy a notebook...any notebook. It doesn't have to be an actual "journal" that you'd buy at a bookstore. Keep it nearby at ALL times. When you write in it, people tend to think that it's school or work related anyway. ; )
Resources: My thoughts and life.
EmpressNia has gotten 2 cheers on this entry.
- VardaElentari cheered this 5 years ago
- PinkCoffeeMug cheered this 5 years ago


text:
TPB/REPEAT on Facebook
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Category Archives: Leah Sorensen-Hayes
And the Winner of the Industrial Revolution Design Challenge is….
The winner of the Industrial Revolution challenge is Emelia Haglund! Emelia's design, inspired by changes in weaving during the Industrial Revolution and the Jacquard loom, was awesome from afar and up close. Emelia's use of color was appealing and unique … Continue reading
Design Challenge Two: Leah Sorensen-Hayes
What struck me when I did an initial Google search of Industrial Revolution images were the rows and rows and rows of machines in the early factories and rows and rows and rows of cables and girders in the iron … Continue reading
In the Studio with Leah Sorensen-Hayes
Congratulations, Michele, on your double win and your elegant dwellings! And thank you, judges, for your very constructive feedback and analysis. It's fascinating how many issues need to be juggled to make a fabric quilter-friendly, and how little a quilter … Continue reading
Design Challenge One: Leah Sorensen-Hayes
Leah Sorensen-Hayes' Tiny Dwellings… I'm a sucker for a thatched roof, so my "Tiny Dwelling" designs zero in on the rondavels–one room, circular huts with conical, thatched roofs–of the Basotho people of Lesotho, South Africa. Some of the huts are … Continue reading
TOP TEN: Leah Sorensen-Hayes
Name: Leah Sorensen-Hayes Location: Lincoln, Nebraska Leah Sorensen-Hayes is a native Nebraskan and the studio assistant to studio quilter, Michael James, at the University of Nebraska in Lincoln. In 1993 Leah earned her BFA in ceramics at the University of … Continue reading


text:
By Sean O'Connell
hollywoodnews.com: Reese Witherspoon, whose latest film "This Means War" opens in theaters next week, will join editor Kevin Tent, A.C.E. to present "The Descendants" director – and her "Election" collaborator – Alexander Payne with the ACE Golden Eddie Filmmaker of the Year honor at the 62nd Annual ACE Eddie Awards. They will be held on Feb. 18.
The black-tie event will take place in the International Ballroom of the Beverly Hilton Hotel.
Witherspoon and Tent will be joined by industry luminaries such as Clint Eastwood, who will be presenting to Career Achievement honoree Joel Cox, A.C.E. and Dick Wolf who will present to Career Achievement Honoree Doug Ibold, A.C.E.
Additional presenters include Robert Forster, famed editor Anne Coates, A.C.E., Rumer Willis (90210), Dominic Purcell (Prison Break, Castle), Robert Morse (Mad Men), Erika Christensen (Parenthood), Matthew Lillard (The Descendants), Laurie Holden (The Walking Dead), Missi Pyle (The Artist), Penelope Ann Miller (The Artist), Donald Faison (The Exes) and Kyle Chandler (Friday Night Lights).
As previously announced, Patton Oswalt will serve as the evening's MC.
Nominees for the 62nd Annual ACE Eddie Awards were previously announced and can be found at www.AMERICANCINEMAEDITORS.com.
Awards Alley brings you the best Oscar coverage. Click below to read our exclusive interviews with:
- Harvey Weinstein
- The cast of "The Artist."
- Kenneth Branagh for "My Week With Marilyn."
- Bennett Miller talks "Moneyball."
- Producer Jim Burke for "The Descendants."
- Sir Ben Kingsley and Chloe Grace Moretz for "Hugo."
- Tilda Swinton for "We Need to Talk About Kevin."
- David Fincher, Daniel Craig and Rooney Mara on "The Girl With the Dragon Tattoo."
- Viola Davis and Octavia Spencer for "The Help."
- Tate Taylor for "The Help."
- Woody Harrelson for "Rampart."
- Gavin O'Connor for "Warrior."
- Gary Oldman and Colin Firth for "Tinker, Tailor, Soldier, Spy."
- Charlize Theron, Patton Oswalt, Jason Reitman and Diablo Cody for "Young Adult."
- Steve McQueen for "Shame."
- Glenn Close for "Albert Nobbs."
- Seth Rogen and Will Reiser for "50/50."
- Producer Grant Heslov for "The Ides of March."
For complete Oscar and Film Festival coverage, visit our Awards Alley for the latest news items, reviews and interviews all season long.
Follow Hollywood News on Twitter for up-to-date news information.
Hollywood News, Hollywood Awards, Awards, Movies, News, Award News, Breaking News, Entertainment News, Movie News, Music News
Tag Archives: Ace the Bat-Hound
Oscars: Reese Witherspoon to present to Alexander Payne at ACE Eddie Awards – AWARDS ALLEY
By Sean O'Connell


text:
Once again, Lexus has managed to increase sales for June 2013. Lexus sold a total of 21,355 units for June which is a gain of over 10% over the same period last year. The Lexus ES, LS and RX continue to top the Lexus sales charts while the all-new 2014 Lexus IS officially went on sale just last Friday. Lexus enjoys increases in both new car and certified pre owned car sales.... Read more
Lexus Sales Increase For June 2013July 3, 2013
Lexus LS Is The Quality King According To J.D. PowerJune 24, 2013
Lexus ES To Be Built In The United StatesApril 19, 2013
No Worries Mate, Lexus ES Returns Down Under!February 25, 2013
Lexus Defines Sporty Luxury With New Special EditionsOctober 4, 2011
Lexus Earns Four Segment Awards in 2011 From J.D. PowerJune 24, 2011
The return of the Lexus ES 300...h?December 17, 2010
« Prev 1 Next »


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text:
You run SIMSInst.exe and choose the "This computer will be used as a SIMS document server" option. Point the SIMS folder and SIMS Setups folder to their respective locations and then set up your DMS:
The SIMS Document storage path is where your DMS files will be kept, the default location is C:\DOCSTORAGE. It automatically creates the full folder tree during install (C:\DOCSTORAGE\<COMPUETERNAME>\<SQLINSTANCE>\<SIMS DATABASE>)
Usually, you would have copied the folder over already from the old server to this location. The folder that is named after the computer once copied gets renamed. Once installed, in SIMS .net, go to Tools | Setups | Document Management Server and update the computer name in there too so it points to the new server. Once done, save and test. if it comes back as passed, your DMS will be working.


text:
main index
23 years ago, twelve strange children were born in England at exactly the same moment. 6 years ago, the world ended. This is the story of what happened next.FreakAngels is a webcomic written by Warren Ellis, author of Nextwave/Transmetropolitan, transhumanist and noted Crazy Awesome British person, with art by Paul Duffield.Set six years after apocalyptic flooding destroys modern civilization (at least in Great Britain), the story follows the self-styled "FreakAngels" - a dozen 23-year-olds born at the exact same moment, all with purple eyes, pale skin and an array of mental powers that include telekinesis, telepathy, mind control, and unique individual gifts.The comic is set in the London district of Whitechapel, now flooded with a good 20 feet of water, and populated by refugees. The FreakAngels are essentially in charge. They're responsible for the steam-powered machines that purify water, the scavenging of artifacts from the pre-flood days, defense against raiders from other neighborhoods, and general enforcement of order. But the raids are getting bolder, the population of Whitechapel is growing too large for their jury-rigged equipment to feed, and the exiled twelfth FreakAngel is looking for revenge on his old family.Ellis and Duffield turned out six full-color pages a week; it ended at 144 episodes (six volumes of the paper edition) on August 5, 2011. It can be seen here.
This comic provides examples of:


text:
There's a discussion going on about making money from genealogy blogs (and genealogy in general). In my opinion, it's long overdue. I'm tired of tiptoeing around these issues.
It started in the comments on Joan Miller's Genea-Bodies: The New Somebodies. Then it continued with tons of frank comments on Marian Pierre-Louis' Facebook page. Michael Hait also has a thoughtful post, and now Thomas McEntee is starting a whole series on the topic. Lynn Palermo also revived an old post for further discussion.
I'm not writing a whole post about this today, because I've said plenty in those comments and on Facebook already, and it's time for me to do some actual paying work. But if you're not reading this stuff, you really should be.
Photo by herval


text:
The Federal Aviation Administration is proposing a civil penalty of $689,800 against FedEx for allegedly violating hazardous materials regulations while handling shipments in 2009.
The FAA said it found the alleged violations during a dangerous goods inspection at a FedEx Express cargo handling facility at Bradley International Airport near Hartford, Conn., from Aug. 31 to Oct. 1, 2009.
In 89 instances from June 13 to Sept. 4, 2009, the FAA alleged, FedEx "failed to provide pilots-in-command with complete, accurate information on the nature, quantity and weight of hazardous materials loaded on their aircraft."
FedEx also accepted four hazmat shipments for air transport when the materials "were not accurately described and certified in the accompanying shipper's documents," the FAA said. Those took place on June 18 and Aug. 26, 2009.
"Pilots must know they are carrying dangerous goods so they can take all necessary safety precautions," said FAA Administrator Randy Babbitt. "Shippers and airlines must follow the rules so they are able to move these materials safely."
The agency said it was sending FedEx enforcement letters detailing the allegations, and the company had 30 days to respond.
-- Contact John D. Boyd at email@example.com. Follow him on Twitter @jboydjoc.


text:
RuthGHealth! Happiness!
Tequendama Falls in Colombia, from www.car.gov.co
And great cascades of joy!
May this year be your most beautiful yet, Waterfall Nymph! 4 years ago
10 years after introducing 43 Things to the world, we have decided we have met our last goal: completing the incredible experience that has been 43 Things. Please join us in giving one last cheer to all the folks who have shared their goals with the world, as well as all the people who have worked at The Robot Co-op to build this incredible website. We won a Webby Award, published a book, and brought happiness to a lot of people.
Starting today, 43 Things users can export their goals and entries from the site. Starting August 15, we will make the site "read only". 43 Things users will still be able to view the site and export their content, but we won't be taking any new content from users. We hope to leave the site up for folks to see and download their content until the end of the year. Ending on New Year's Eve takes us full circle.
It has been a long ride (one of our original goals was to "build a company that lasts at least 2 years" - we beat that one!) While we wish the site could live on, it has suffered from a number of challenges - changes in how people use the site, the advertising industry, and how search engines view the site. We wish the outcome was different – but we've always been realistic about when our goals are met and when they aren't.
As of today, you will be able to download your goals and entries. See more about that on the FAQ page. Thanks for 10 great years of goal-setting and achieving.
- The Robots.
Tequendama Falls in Colombia, from www.car.gov.co
And great cascades of joy!
May this year be your most beautiful yet, Waterfall Nymph! 4 years ago
All the way from Mexico, here's today's sunset for you! I hope you had a fabulous day, and I wish you a great year to come :) 4 years ago
I was working nearly all day but I couldn't go to bed without wishing you a very happy birthday; I hope it was full of positivity, great family experiences, and sugar. Mmm, sugar. I thought this cake was appropriate; small, but appropriate. 4 years ago
Happy Birthday to my 43things friend. There are many things I admire about you and the everyday things you celebrate from gardening to new fitness adventures, reading, planning parties for the chum and doing other special things for your family. Your goals reflect honestly the actions you take and the way you live your life. They are truly inspired and inspirational. I thank you for visiting me in Japan…you are now one of the few people who can understand my memories of Japan and the places we visited. And I thank you for the thoughtful messages and gifts you send…You are a true and constant friend, online and off. I wish you the happiest of birthdays today and happy days for the whole wonderful year! 4 years ago
She's still two years out from turning 43 but she's already completed one of the 43 things on her list to complete before that special birthday. I didn't start my list until I had a year left to go, so she's definitely shown that she's thinking ahead. I'm really excited to watch as she works on accomplishing things too, especially the running goals and triathalons. I wish I had someplace that I could practice swimming so that I could work on that too. I wonder how much a lap pool would cost. And because she doesn't think anyone knows where her city is, let me say for the record that I know where it's at because I drove by it on my way to visit a friend in Healdsburg over a decade ago. Here are my wishes for her for the coming year:
May you make finishing a will a priority for Chum's sake. May you continue to exercise six times a week and eat right, both of which will help you get back to your pre-pregnancy weight. And may you revisit every piece of lingerie that you own, possibly on those date nights with your husband. 4 years ago
so pick one of these and make it the cocktail of the day and celebrate…
Happy Birthday! 4 years ago
Some birthday flowers to brighten your special day.
Happy birthday thrice! xxoo (((WN))) 4 years ago
...Happy Birthday to you! Happy Birthday de-ear Waterfall Nym-ph, Happy Birthday to you!!
I hope you are having an amazing day WN, you deserve a truly wonderful celebration as you are a truly wonderful woman!!
Lots and lots of love, hugs and kisses. Xx 4 years ago
a happy, healthy, fun and filled with love birthday. 4 years ago
Hope you are having a wonderful day. Sending best wishes your way!
~sc 4 years ago
to a terrific 43t friend. I hope it's a wonderful day 4 years ago
and soon you'll have all this bounty! 4 years ago
These came from our trip to Himeji. See it in the background? 4 years ago
I hope this year finds you completing more races and sharing more special moments with your family and of course sharing all about it online! 4 years ago
Happy Birthday wishes, from me to you: Get healthy, stay healthy, be happy. Have a great day! 4 years ago
Happy Birthday and Cheers! Have a wonderful day.
"Sometimes too much to drink is barely enough."
-Mark Twain4 years ago
Wishing you a wonderful day and excellent year.
Mary (MFM) 4 years ago
You have one of the best screen names ever! I hope you have a wonderful day. Here's a lovely and healthy cake for you.
4 years ago
Homemade cookies! 4 years ago
We won't be needing any of this stuff… 4 years ago


text:
Gale Partners With The Associated Press To Digitize Holdings
FARMINGTON HILLS, Mich., April 8, 2013 /PRNewswire/ -- Gale, part of Cengage Learning and a leading publisher of research and reference resources for libraries, schools and businesses, today announced an agreement with the Associated Press (AP) to digitize their corporate archives, including millions of pages of news copy (some never-before published), bureau records, correspondence, the personal papers of reporters and more. This agreement follows on the large-scale partnerships Gale has signed with the Smithsonian Institution and the National Geographic Society.
(Logo: http://photos.prnewswire.com/prnh/20070724/NYTU125 )"We're thrilled to be embarking on this partnership with one of the most respected news organizations in the world," said Frank Menchaca, executive vice president, research solutions, Cengage Learning. "Together we will provide users and customers an opportunity to access and analyze the archival materials that will reveal how news, public opinion, and history are constructed and shaped." This agreement covers a variety of materials and includes content that has never been published. Covered under the agreement are the notes and observations of AP journalists, potentially giving widely reported events a new perspective, while also providing valuable insight into the stories that were not reported. In addition, the agreement encompasses records from dozens of U.S. and foreign bureaus, and special collections such as photographs, manuscripts, sound recordings and oral histories. "The Associated Press has been reporting the news since 1846; with Gale's expertise, AP can make its own historical record more widely available to the research community," said Valerie Komor, Director of the AP Corporate Archives. Throughout the course of this multi-year project, Gale will work with an advisory board of professors and subject matter experts to guide the development of the digital products, with the first products available within the next year. The products will be a valuable asset for academic libraries, including students and faculty in journalism and history, as well as high school and public libraries, and will offer opportunities for new research angles on popular topics.
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2013 Award of Honor: Garage
Photo Credit: Amos Morgan Photography
2013 Award of Honor: Garage
The Disaster Preparedness & Response (DP&R) Task Force informs and coordinates design professionals' action in preparing for and responding to disaster conditions. Activities have included offering seminars and workshops to prepare design profesionals for work of this kind to serve communities and clients, and organizing relief efforts.
For current information on the Disaster Preparedness and Response Task Force's activities visit their website at www.aia-dpr.org.
For those that have taken the ATC-20 class, we encourage you to fill out the application to be an Emergency Worker with King County.
Megan Harmon, 206.448.4938
AIA Disaster Assistance Program
Essentials for Healthy Homes Practitioners Course
Architects Without Borders Seattle
"The Changing Role of Architects in Disaster Response"
AIA Tsunami Response
Mississippi Mission
Earthquakes, Tsunamis & Architects 9/21/05
Seismic Tool Kit 10/04
Good design makes a difference


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Elin Gets $750 Million in Tiger Woods Divorce [Updated]
And Tiger's not allowed to bring his ladies near the kids.
Skip to content, or skip to search.
Skip to content, or skip to search.
And Tiger's not allowed to bring his ladies near the kids.
"I think I was out of my mind."
After all, he has his own wounds to lick.
Now we can all sleep easy.
He needs to lose fifteen pounds before Oscar time, he says.
And if the dudes are fashion gays.
"It was so scary, but I was laughing."
Harry Morton has begun claiming his relationship with the former actress never happened.
Why don't people recognize him at Marquee anymore?
That's what 'Page Six' thinks. Plus, the bus that smells like pot on West 48th Street is Willie Nelson's. In the gossip roundup.


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Shoes & Accessories
mouse over photo to zoom click for larger image
Silk Burnout Scarf
Featherlight silk scarf patterned with a geometric design in tones you'll cherish season after season. 100% Silk. Dry clean. Imported. Approximately 22" x 74".
We're so sorry: this item sold out sooner than expected. For an equally stylish substitute, please call our Style Experts at 1.877.948.2525. Or click on Live Help below for immediate assistance.


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Catching a baseball game in downtown Detroit has never been so easy or fun until this baseball hotel package! Enjoy the All-American sport at Comerica Park, fabulous hotel accommodations, & unrivaled excitement in the heart of the Motor City. Grand Slam Baseball Fan package includes deluxe guest room accommodations, breakfast for two in hotel restaurant, plus children under 12 eat free. Complimentary valet parking for one car, $20 in Tigers Fun Money valid at Comerica Park. Be sure that promotional code P42 appears in the Corporate/Promotional code box when making your online reservation, or call 800-228-9290 and ask for promotional code P42.
Grand Slam Baseball Fan Package at the Detroit Marriott at the Renaissance Center Web Site
Detroit Marriott at the Renaissance Center
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