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User Reviews for Dynacirc
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
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A Pilot Study of MabThera (Rituximab) Evaluated by MRI in Patients With Rheumatoid Arthritis.
|Tracking Information
|First Received Date ICMJE
|July 17, 2007
|Last Updated Date
|October 7, 2013
|Start Date ICMJE
|October 2007
|Primary Completion Date
|July 2010 (final data collection date for primary outcome measure)
|Current Primary Outcome Measures ICMJE
|Synovitis, bone marrow edema and erosions, measured by MRI. [ Time Frame: 6 months ] [ Designated as safety issue: No ]
|Original Primary Outcome Measures ICMJE
|Synovitis, bone marrow edema and erosions after 6 months, measured by MRI.
|Change History
|Complete list of historical versions of study NCT00502853 on ClinicalTrials.gov Archive Site
|Current Secondary Outcome Measures ICMJE
|Original Secondary Outcome Measures ICMJE
|Efficacy: Ritchie articular index, HAQ, DAS28, laboratory markers of disease activity, at weeks 4, 12 and 24 after MabThera cycle. Safety: AEs, laboratory parameters.
|Current Other Outcome Measures ICMJE
|Not Provided
|Original Other Outcome Measures ICMJE
|Not Provided
|Descriptive Information
|Brief Title ICMJE
|A Pilot Study of MabThera (Rituximab) Evaluated by MRI in Patients With Rheumatoid Arthritis.
|Official Title ICMJE
|Pilot Study to Evaluate the Effect of Mabthera in Combination With MTX in the Inhibition of Progression of Synovitis, Bone Marrow Edema, and Erosions Evaluated by Magnetic Resonance Imaging (MRI) in the Hand of Patients With Rheumatoid Arthritis.
|Brief Summary
This single arm study will measure the effect of MabThera in combination with methotrexate on the progression of synovitis, the extent of bone marrow edema, and the number of erosions in the wrist and hand of patients with rheumatoid arthritis, using a new MRI technique. Patients will receive MabThera 1000mg i.v. on days 1 and 15, in combination with a stable dosage of 10-25mg/week methotrexate throughout the duration of the study. Further courses of MabThera will be provided to eligible patients. MRI will be performed 1-2 weeks before treatment initiation, and repeated 1 and 6 months after the first MabThera infusion. The anticipated time on study treatment is 1-2 years, and the target sample size is <100 individuals.
|Detailed Description
|Not Provided
|Study Type ICMJE
|Study Phase
|Phase 4
|Study Design ICMJE
|Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Condition ICMJE
|Rheumatoid Arthritis
|Intervention ICMJE
|Study Arm (s)
|Experimental: 1
|Publications *
|Not Provided
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
|Recruitment Information
|Recruitment Status ICMJE
|Enrollment ICMJE
|Completion Date
|July 2010
|Primary Completion Date
|July 2010 (final data collection date for primary outcome measure)
|Eligibility Criteria ICMJE
Inclusion Criteria:
Exclusion Criteria:
|18 Years to 75 Years
|Accepts Healthy Volunteers
|Contacts ICMJE
|Contact information is only displayed when the study is recruiting subjects
|Location Countries ICMJE
|Administrative Information
|NCT Number ICMJE
|Other Study ID Numbers ICMJE
|Has Data Monitoring Committee
|Not Provided
|Responsible Party
|Hoffmann-La Roche
|Study Sponsor ICMJE
|Hoffmann-La Roche
|Collaborators ICMJE
|Not Provided
|Investigators ICMJE
|Information Provided By
|Hoffmann-La Roche
|Verification Date
|October 2013
ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP


text:
Kihei Condo Rental Photos and Description
3 BR, 3 bath, ocean view. One of the best values in Maui.
3 BR, 3 bath condo at the Maui Sunset in Kihei, HI. Unit A422 is completely furnished with linens, laundry, kitchen utensils, refrigerator, microwave, coffee maker, toaster, glass top stove and oven, flat panel cable TV, and high speed wireless internet. Master BR has queen bed and other BR's have twin beds which can be configured for king size. This unit is located on 4th floor at the end of the building closest to the water. The view from the lanai affords an unsurpassed 270 degree view including the coastline and Mt. Haleakala as well as the large pool and grounds. Whale watching from the lanai during whale season (January – April) is a favorite pastime. Windsurfers provide a colorful view daily. Unit sleeps 6 plus sofa bed in living room. Maximum occupancy 8 persons. Unit refurbished in October 2012. We have many repeat visitors and we do not believe you will be disappointed if you should choose to be our guests.
- Suitability:
- Minimum Age Limit for Renters
- children welcome
- non smoking only
- pets not allowed
- wheelchair accessible
About Donald L Starkey
At the time we purchased this property, my partner and I both lived in Phoenix, AZ. One of us moved to Georgia in the '90s. We are both physicians, one retired and the other very near retirement.
Donald L Starkey purchased this condo in 1977
Why Donald L Starkey chose Kihei
We looked for several years at properties but this one appealed to us because of the incredible view. We originally purchased this property because of the incredible view. The condo is very well situated to local businesses and tourist interests. It also has the amenities that most guests are looking for including pool, tennis, volleyball, putting green, barbecue facilities, concierge and absolutely beautiful grounds.
What makes this condo unique
All photos are taken from the lanai , the interior of condo or in the courtyard below. Visitors tell us that the view from the lanai is the best in the entire complex. Being on the 4th floor not only provides increased security but also exposure to increased ventilation which requires very little air conditioning, if any.


text:
Michigan Wheel's Xchangeable Hub System absorbs impact and stress caused by shifting gears and is designed to spin under significant impact to help protect your lower unit. XHS / XHS II is also designed to be interchangeable with Mercury's Flo-Torq II hub system, potentially saving you money when replacing or upgrading your propeller.
Michigan Wheel's XHS Hub Kits are designed for use with our Vortex and Apollo Series propellers.
Ambush towboat propellers are 100% CNC machined for the ultimate in accuracy and consistency. Michigan Wheel Marine developed the CNC machining process for propellers in the mid – 1980's and revolutionized the way propellers were manufactured. Originally, the CNC machining technology was used to manufacture custom propellers for large mega-yachts where accuracy is critical and design geometry is complex. Now, that same technology is being used to provide the best towboat propeller on the market.


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Fred Levy, M.D. Interviewed by The Baltimore Sun
Fred Levy, senior co-director of the Center for Medicine and Law, appears as an expert in a Nov. 12 story by The Baltimore Sun about a proposal to manndate that employers provide paid sick leave to workers. "This may be beneficial, but it's a question we can attempt to answer a little more rigorously before marching forward," said Levy.
Read the article
Center for Medicine and Law Launch Annoucement
In February , 2011 The Johns Hopkins University and the University of Baltimore School of Law announced that they would jointly launch what is believed to be the nation's first academic center for medicine and law that focuses on the health care provider.


text:
AB TEO LT, Lithuania's biggest communications company, said profit fell 2 percent in the first quarter from a year earlier amid increased operating expenses for one-time items.
Net income declined to 37.15 million litai ($14.13 million) from 37.73 million litai, the Vilnius-based company said in a statement to the stock exchange today. Sales rose 2.5 percent to 190.49 million litai.
To contact the reporter on this story: Milda Seputyte in Vilnius at email@example.com
To contact the editor responsible for this story: Balazs Penz at email@example.com


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Narrow your search
The company racks up nearly 25 million more iPhones sold this fiscal year than last. What about iPads, Macs, and more? Here's the full breakdown.
The company's venture round will be led by DST Global, according to Recode's Kara Swisher. Other VCs, including Google Ventures and Shasta Ventures, will also join the round.
Mimicking Workday and Trulia, the U.S. online education hub files -- secretly -- for an initial public offering.
Uber's fledgling service in China will face tough competition from taxi-hailing company Kuaidi, which already boasts more than 150 million riders in 350 cities.
Pros and enthusiasts in the US can rejoice that many of Canon's SLR lenses are a notch less pricey now. Better exchange rates might deserve some of the credit.
Players of the pixelated building block game have taken its virtual simulation tools to an unprecedented level: building functioning hard drives that can read and write data.
The mysterious marginalia found in a 16th-century edition of Homer's Odyssey has been identified by a digital humanities student from the Archivio di Stato di Milano in Italy.
The largest cable provider in the U.S. has signed a deal to pay out $150 million for a slice of set-top box maker Arris.
In order to assuage the creationist protesters who complain that Neil DeGrasse Tyson's series doesn't allow for a God-centric explanation, Funny Or Die creates a creationist version. It lasts mere minutes.
Three of the new additions are in the U.S., while three other markets are in Puerto Rico.


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- Click to Talk
View property, WalkScore, and Driving Directions
Fax: (925) 798-9328
We offer one and two bedroom apartments for rent in Concord, California. With amenities such as ceiling fans, plush carpeting, fully equipped kitchen, window coverings, controlled access and much, much more!
Rents starting at $1,050
Floorplans and Pricing
1 Bedroom
|One Bedroom
|1 Bathroom
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|Two Bedroom
|1 Bathroom
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Features and AmenitiesBack to Top
Special Features
- Gated Community
- Covered Parking
- Sparkling Swimming pool
- Just minutes from downtown, walk to shopping
- Easy access to Highway 242 and I-680
- Minutes to BART
- Garden Setting
- Private Patio or Balcony
- Spacious Floor Plans, Cabinetry & Ceiling Fans
- Controlled Access
- Near Schools and Restaurants
Community Features
- Apartment
- Barbeque Area With Grills
- Condo
- Controlled Access
- Corporate Housing
- Courtyard
- Covered Lot
- Disability Access
- Efficiency
- Freeway Access
- Garden Style
- Garden Style
- Gated Entry
- Gated Community
- Laundry Facility
- Market Rate
- Mid Rise
- Mid Rise
- Mixed Use
- Mixed Use
- On Street Parking
- Planned Social Events
- Pool
- Public Transportation
- Short Term Lease
- Standard
- Street
- Surface Lot
- View
Apartment Amenities
- Air Conditioning
- Broadband Internet Access
- Cable or Satellite
- Carpet
- Ceiling Fan
- Dishwasher
- Extra Storage
- Garbage Disposal
- Individual Locking Bedrooms
- Internet Access
- Large Bedrooms
- Patio or Balcony
- Private Bathroom
- Window Covering
- Wireless Internet Access
Pet Policy
Sorry, no pets allowed.
Local Schools
- Glenbrook Middle School
- Meadow Homes Elementary School
- Ygnacio Valley High School
We believe school data to be accurate, but do not guarantee that. Please be sure to verify where your children will attend school before making your housing decision.
As you search for your perfect apartment, please keep in mind that rental rates (including specials and discounts) and availability are very fluid in the apartment industry. Based on many factors, the rental rates (including specials and discounts) and availability can actually change not just daily, but hourly, if not even more quickly. While our advertisers do take steps to keep their information current, the rental rates or availability you may find here now at ForRent.com may not be the same as when you contact the communities.


text:
The Deal
$30 for a La Marais gift set ($73.50 list price). Each gift set includes:
- One 7-ounce box of all-natural truffles (22–24 pieces)
- One 6-piece box of gel fruits
- One crepes dentelle (chocolate crepe)
$33 for a Montmartre gift set ($87 list price). Each gift set includes:
- One 9-piece signature chocolate box
- One 7-ounce box of all-natural truffles (22–24 pieces)
$33 for a Vendome gift set ($102 list price). Each gift set includes:
- One 7-ounce box of all-natural truffles (22–24 pieces)
- One 7-ounce box of cappuccino truffles (22–24 pieces)
- One 7-ounce box of champagne truffles (22–24 pieces)
Free shipping
Chocolate Gift Sets
An excellent gift for family members, friends, special someones, and visiting heads of state, each chocolate gift set contains an assortment of flavorful confections. Chocolates, chocolate crepes, and gel fruits satisfy any sweet tooth, and all-natural truffles dusted in cocoa powder make the perfect companions for glasses of champagne.
- Assortments of chocolate, truffles, and gel fruits
- All-natural truffles
- Coated with fine cocoa powder
- Great holiday gift
How to get your goods: by purchasing this Groupon and providing your name and shipping address, your order is complete!
For questions pertaining to this deal, please visit the deal Q&A on this page. For post-purchase inquiries, please contact Groupon customer service.
View the Groupon Goods FAQ for additional information, including how list price is determined.
Like Groupon Goods on Facebook for hand-picked deals, product giveaways, and more Goods stuff.
In a Nutshell
Assortments of chocolates, truffles, and gel fruits
The Fine Print
Limit 3 per person, may buy 2 more as gifts. Free shipping. Does not ship to AK/HI/Canada/Puerto Rico. Most orders are delivered within 2 1/2 weeks from the purchase date. Does not ship to PO boxes. Final sale. No returns unless defective. See return policy. Must pay applicable tax and provide name and shipping address at checkout, which will be shared to facilitate shipping. Goods sold by Groupon Goods.


text:
Print Options
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Chocolate Walnut Squares >
Full Page
Include these items:
Nutritional Facts
Select reviews >
Chocolate Walnut Squares
Rich and satisfying, these bars create a symphony of flavors with every bite. The nutty crust, exquisite chocolate layer and the creamy frosting make this dessert one of my personal favorites. It's fun to take these treats to a potluck. —Anne Heinonen, Howell, Michigan
20-24 Servings
Prep: 20 min. Bake: 30 min.
1 cup butter, softened
2 cups sugar
4 eggs, lightly beaten
3 teaspoons
McCormick® Pure Vanilla Extract
2 cups all-purpose flour
1/2 teaspoon salt
2 cups chopped walnuts
2 ounces unsweetened chocolate
5 tablespoons all-purpose flour
1 cup milk
1 cup butter, softened
1 cup confectioners' sugar
2 teaspoons
McCormick® Pure Vanilla Extract
In a bowl, cream butter and sugar. Beat in eggs and vanilla. Add
flour and salt; mix well. Fold in walnuts. Spread half of batter
into a greased 13-in. x 9-in. baking pan. Add chocolate to the
remaining batter; mix well. Carefully spread over batter in pan.
Bake at 350° for 30-35 minutes or until a toothpick comes out
clean. Cool completely.
For frosting, in a saucepan, combine flour and milk until smooth.
Bring to a boil. Cook and stir for 1-2 minutes or until bubbly and
© Taste of Home 2014
2 of 2
Chocolate Walnut Squares
Directions (continued)
thickened. Cool completely.
In a bowl, cream butter and confectioners' sugar. Add vanilla and mix
well. Gradually add the milk mixture; beat for 5 minutes. Frost
cake. Store in the refrigerator. Yield: 20-24 servings.
Nutritional Facts:
1 serving (1 piece) equals 352 calories, 23 g fat (11 g saturated fat), 78 mg cholesterol, 220 mg sodium, 33 g carbohydrate, 1 g fiber, 5 g protein.
© Taste of Home 2014


text:
Related Content: Fremont County Commission
County fair attendance up, ticket sales down
Sep 27, 2013 - By Eric Blom, Staff Writer:  The fair board has considered adding and reorganizing events.
Judge orders county to pay winner's fees in voting suit
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Commissioners plan retreat to mull over health care concerns
Sep 13, 2013 - By Eric Blom, Staff Writer:  Rising health care costs took a big bite out of Fremont County's general fund in the last budget cycle, and the figure has climbed year after year. ... [more]
Justice center prep continues; latest plan expected in October
Sep 13, 2013 - By Eric Blom, Staff Writer:  Architects are to have detailed plans for a new Riverton justice center finished in October.
Commission votes against funds for Lander center
Sep 11, 2013 - By Eric Blom, Staff Writer:  The county's tight budget led commissioners on Aug. 13 to decide against contributing any funds to rebuild the Lander Community Center.
Program director eyes Major property for new day reporting center site
Selling alcohol on the reservation
Sep 3, 2013 - By Steven R. Peck:  It was banned for a reason, and there ought to an equally good one to reinstate it
Tribes, county working on liquor license rules
Aug 30, 2013 - By Eric Blom, Staff Writer:  For the first time in decades, serious discussion is taking place on re-establishing alcohol sales on the Wind River Indian Reservation.
When possible, local engineers preferred on 1 percent projects
Rules being developed for liquor licenses on reservation
Aug 25, 2013 - By Eric Blom Staff Writer:  Tribal and county governments are developing a memorandum of understanding about granting liquor licenses to businesses on the Wind River Indian Reservation. ... [more]
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County OKs funds for reconstruction of Green Mountain recreation facilities
Aug 9, 2013 - By Eric Blom, Staff Writer:  Funds are in place to redevelop the Green Mountain recreation area after county commissioners approved a $250,000 line of credit for the project on Tuesday. ... [more]
Riverton justice center plan rises again
Aug 7, 2013 - By Eric Blom, Staff Writer:  The possibility of funding from the Wyoming Legislature has spurred the Fremont County Commission to begin the process of designing a new Riverton justice ... [more]
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Aug 6, 2013 - By Eric Blom, Staff Writer:  Most Fremont County property owners likely will see a small rise in their tax rates this year after commissioners approved a package of mill levies Monday. A ... [more]
Experts at budget time
Aug 5, 2013 - By Steven R. Peck:  Increasingly, spenders and consumers see themselves as interchangeable
Homicide will not be prosecuted, county attorney determines
Jul 31, 2013 - By Eric Blom, Staff Writer:  Fremont County Attorney Michael Bennett said criminal liability could not be placed on any one person in the death of 4-year-old Thunder Littlethunder Jr. of ... [more]
Ambulance disagreement settled for now with OK of $2.8M budget
Jul 28, 2013 - By Eric Blom, Staff Writer:  After delays amid sometimes heated discussion for several weeks, Fremont County Commissioners have approved a $2.8 million budget for the Fremont County ... [more]
Museums board to move forward with examination of one-director model
Jul 25, 2013 - By Eric Blom, Staff Writer:  A change in leadership coincided with a new direction for the Fremont County Museums Board. At a July 11 meeting, the group chose to examine a management ... [more]
First fuel-tax-funded job is in Fremont County
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Interim ambulance chief named
Jul 15, 2013 - By Eric Blom, Staff Writer:  As of Friday, the Fremont County ambulance department has its interim director.
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(713) 461-3505
500 Texas St, Houston, TX 77002
Products: Interior Designer, Home Renovation, Custom Window Treatment, Furniture And Accessories, Interio...
Services: Interior Designer, Home Renovation, Custom Window Treatment, Furniture And Accessories, Interio...
Latest review: "Thank you for all of your hard work, your endless patience, and your wonderful generous frie..."
3.7 Miles
(713) 401-2861
Serving Houston, TX
Products: Custom Office Furniture
Services: Woodworks, Metalworks, Glassworks, Refinishing, Upholstery And More.
Latest review: "-Our custom boardroom table is an absolute masterpiece! Very detailed,talented and professio..."
14.5 Miles
(281) 851-1625
Serving Houston, TX
Latest review: "I ordered a spa basket for my girlfriend's birthday to be delivered to her office. Everyone ..."
7.1 Miles
(832) 252-6688
7250 Harwin Dr, Houston, TX 77036
Products: Draperies, Fabric, Silk, Tassels, Trimmings, Decorative Supplies, Trims, Decorating Accents
Services: Warehouse Direct
Latest review: "This has to be the best place for home decorating fabric I have ever been to. What you see ..."
6.5 Miles
(713) 266-0017
5810 Hillcroft St, Houston, TX 77036
Products: Handbags, Wallets, Clutches, Watches, Sunglasses, Cross Body Bags, Evening Bags, Evening Handba...
Services: Wholesale Handbags, Wholesale Bags, Wholesale Wallets, Wholesale Watches, Wholesale Wallets, Ha...
Latest review: "Vianova Carries, unique and fashionable bags! The quality is great and everytime I go they h..."
11.8 Miles
(281) 497-3100
1903 S Dairy Ashford Rd, Houston, TX 77077
Products: Candy Bouquet, Collectibles, Tulips, Bouquets, Chocolates & Candies, Roses
Latest review: "I love the same day flower delivery service that they have. I order a Dozen red roses for my..."
5.5 Miles
(713) 396-6956
6222 Richmond Ave Ste 825, Houston, TX 77057
Products: Engagement Rings, Wedding Bands, Diamond Engagement Rings, Diamond Jewelry, Diamond Rings, Cust...
Services: Custom Design And Manufacturing Of Fine Jewelry, Jewelry Repair, Jewelry Refurbishing, Diamond ...
Latest review: "I firmly believe that when you buy an exceptional piece of jewelry it is the same as purchas..."
16.1 Miles
(833) 332-1536
Serving Houston, TX
Latest review: "Im in Purchasing and my company and I were really in a bind...Not only did they have what I ..."
15.2 Miles
(281) 416-9353
Serving Missouri City, TX
Products: Water Softeners, Purifiers, Filters, And Well Water Treatment Systems., Conditioners
Services: Professional Installations, System Service, And Maintenance Contracts.
Latest review: "I just purchased a water conditioner and r/o. the people where very nice, well informed, gre..."
19.3 Miles
(713) 870-6597
12639 Mcswain Rd, Cypress, TX 77429
Products: Vintage Items, Collectible-novelty Pieces, Imported Glassware, Art, Furniture And Fixtures
Services: Art And Craft Workshops
Latest review: "A fantastic shop. Unusual items, collectibles. Bought great values here! I'll do my Christm..."
13.6 Miles
(281) 416-9353
Serving Missouri City, TX
Products: Water Softeners, Well Water Treatment, Reverse Osmosis
Services: Water Softener, Conditioner Service And Parts, Replacement Filters
Latest review: "Excellent Company.. Great customer service and equipment. bought a water softener at a more ..."
15.2 Miles
(713) 910-5977
12100 Gulf Fwy, Houston, TX 77034
Latest review: "What great service. I am very pleased with all the effort of customer service that they offe..."
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