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Publications (27)91.01 Total impact
Article: Ethnic differences in serum adipokine and C-reactive protein levels: The Multiethnic Cohort.[Show abstract] [Hide abstract]
ABSTRACT: Background:Ethnic disparities in metabolic disease risk may be the result of differences in circulating adipokines and inflammatory markers related to ethnic variations in obesity and body fat distribution.Subjects/Methods:In a cross-sectional design, we compared serum levels of leptin, adiponectin, C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) in control subjects (321 men and 930 women) from two nested case-control studies conducted within the Multiethnic Cohort Study consisting of whites, Japanese Americans (JA), Latinos, African Americans (AA), and Native Hawaiians (NH). General linear models were applied to evaluate ethnic differences in log-transformed serum biomarker levels before and after adjusting for body mass index (BMI) at cohort entry.Results:In comparison to whites, significant ethnic differences were observed for all biomarkers except TNF-α. JA men and women had significantly lower leptin and CRP levels than whites and JA women also had lower adiponectin levels. Leptin was significantly higher in AA women (P<0.01), adiponectin was significantly lower in AA men and women (P=0.02 and P<0.001), and CRP and IL-6 were significantly higher in AA men and women. Lower adiponectin (P<0.0001) and CRP (P=0.03) levels were the only biomarkers in NH women that differed from whites; no statistically significant differences were seen for NH men and for Latino men and women. When adjusted for BMI at cohort entry, the differences between the lowest and highest values across ethnic groups decreased for all biomarkers except adiponectin in men indicating that ethnic differences were partially due to weight status.Conclusions:These findings demonstrate ethnic variations in circulating adipokine and CRP levels before and after adjustment for BMI. Given the limitation of BMI as a general measure of obesity, further investigation with visceral and subcutaneous adiposity measures are warranted to elucidate ethnicity-related differences in adiposity in relation to disparities in obesity-related disease risk.International Journal of Obesity accepted article preview online, 13 February 2014; doi:10.1038/ijo.2014.25.International journal of obesity (2005) 02/2014; · 5.22 Impact Factor
Article: Methods for Assessing and Representing Mammographic Density: An Analysis of 4 Case-Control Studies.[Show abstract] [Hide abstract]
ABSTRACT: To maximize statistical power in studies of mammographic density and breast cancer, it is advantageous to combine data from several studies, but standardization of the density assessment is desirable. Using data from 4 case-control studies, we describe the process of reassessment and the resulting correlation between values, identify predictors of differences in density readings, and evaluate the strength of the association between mammographic density and breast cancer risk using different representations of density values. The pooled analysis included 1,699 cases and 2,422 controls from California (1990-1998), Hawaii (1996-2003), Minnesota (1992-2001), and Japan (1999-2003). In 2010, a single reader reassessed all images for mammographic density using Cumulus software (Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada). The mean difference between original and reassessed percent density values was -0.7% (95% confidence interval: -1.1, -0.3), with a correlation of 0.82 that varied by location (r = 0.80-0.89). Case status, weight status, age, parity, density assessment method, mammogram view, and race/ethnicity were significant determinants of the difference between original and reassessed values; in combination, these factors explained 9.2% of the variation. The associations of mammographic density with breast cancer and the model fits were similar using the original values and the reassessed values but were slightly strengthened when a calibrated value based on 100 reassessed radiographs was used.American journal of epidemiology 10/2013; · 5.59 Impact Factor
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ABSTRACT: INTRODUCTION: Mammographic density, a strong predictor for breast cancer incidence, may also worsen prognosis in women with breast cancer. This prospective analysis explored the effect of prediagnostic mammographic density among 607 breast cancer cases diagnosed within the Hawaii component of the Multiethnic Cohort (MEC). METHODS: Female MEC participants, aged [greater than or equal to]50 years at cohort entry, diagnosed with primary invasive breast cancer, and enrolled in a mammographic density case-control study were part of this analysis. At cohort entry, anthropometric and demographic information was collected by questionnaire. Tumor characteristics and vital status were available through linkage with the Hawaii Tumor Registry. Multiple digitized prediagnostic mammograms were assessed for mammographic density using a computer-assisted method. Cox proportional hazards regression was applied to examine the effect of mammographic density on breast cancer survival while adjusting for relevant covariates. RESULTS: Of the 607 cases, 125 were diagnoses as in situ, 380 as localized, and 100 as regional/distant stage. After a mean follow-up time of 12.9 years, 27 deaths from breast cancer and 100 deaths from other causes had occurred; 71 second breast cancer primaries were diagnosed. In an overall model, mammographic density was not associated with breast cancer-specific survival (HR=0.95 per 10%; 95%CI: 0.79-1.15), but the interaction with radiotherapy was highly significant (p=0.006). In stratified models, percent density was associated with a reduced risk of dying from breast cancer (HR=0.77; 95%CI: 0.60-0.99; p=0.04) in women who had received radiation, but with an elevated risk (HR=1.46; 95%CI: 1.00-2.14; p=0.05) in patients who had not received radiation. High breast density predicted a borderline increase in risk for a second primary (HR=1.72; 95%CI: 0.88-2.55; p=0.15). CONCLUSIONS: Assessing mammographic density in women with breast cancer may identify women with a poorer prognosis and to provide them with radiotherapy to improve outcomes.Breast cancer research: BCR 01/2013; 15(1):R7. · 5.87 Impact Factor
Article: Non-Hodgkin Lymphoma and circulating markers of inflammation and adiposity in a nested case-control study: The Multiethnic Cohort.[Show abstract] [Hide abstract]
ABSTRACT: OBJECTIVE: Since immune dysfunction is thought to underlie the development of Non-Hodgkin Lymphoma (NHL), obesity and chronic inflammation may be involved in its etiology. We examined the association of pre-diagnostic inflammatory markers and adipokines with NHL risk. METHODS: We conducted a nested case-control analysis (272 cases and 541 matched controls) within the Multiethnic Cohort. Luminex technology was used to measure a 10-plex panel of cytokines, ELISA assays for adipokines, and an autoanalyzer for C-reactive protein (CRP). Odds ratios (ORs) and 95% confidence intervals (CIs) for tertiles of analytes were estimated by conditional logistic regression. RESULTS: After a median time of 2.7 years from phlebotomy to diagnosis, interleukin (IL)-10 was significantly related to NHL risk (ORT3 vs T1=3.07; 95%CI: 2.02-4.66; ptrend <0.001). TNF-α and IL-8 showed borderline elevated risks, while IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, and CRP were not associated with NHL. Leptin but not adiponectin was related to NHL risk (ORT3 vs T1=0.48, 95%CI: 0.30-0.76; ptrend<0.001). Adjustment for body mass index did not substantially affect the risk estimates. Stratification by subtype indicated significant associations with IL-10 and leptin for follicular but not for diffuse large B-cell lymphoma. Excluding cases diagnosed <1 year after phlebotomy attenuated all associations. CONCLUSIONS: IL-10 was the only cytokine and leptin the only adipokine associated with NHL, but, due to the short follow-up time, pre-clinical effects cannot be excluded. Impact: Although markers of inflammation and adiposity may provide new insights into the etiology of NHL, they need to be assessed many years before clinical diagnosis.Cancer Epidemiology Biomarkers & Prevention 01/2013; · 4.56 Impact Factor
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ABSTRACT: Strong and consistent evidence exists that physical activity reduces breast cancer risk by 10-25 %, and several proposed biologic mechanisms have now been investigated in randomized, controlled, exercise intervention trials. Leading hypothesized mechanisms relating to postmenopausal breast cancer include adiposity, endogenous sex hormones, insulin resistance, and chronic low-grade inflammation. In addition, other pathways are emerging as potentially important, including those involving oxidative stress and telomere length, global DNA hypomethylation, immune function, and vitamin D exposure. Recent exercise trials in overweight/obese postmenopausal women implicate weight loss as a mechanism whereby exercise induces favorable changes in circulating estradiol levels and other biomarkers as well. Still it is plausible that some exercise-induced biomarker changes do not require loss of body fat, whereas others depend on abdominal fat loss. We highlight the latest findings from randomized, controlled trials of healthy postmenopausal women, relating exercise to proposed biomarkers for postmenopausal breast cancer risk.Current Nutrition Reports. 01/2013;
Article: The Effects of Soy Consumption before Diagnosis on Breast Cancer Survival: The Multiethnic Cohort Study.[Show abstract] [Hide abstract]
ABSTRACT: This study tested the hypothesis that prediagnostic soy intake was inversely associated with all-cause and breast cancer-specific mortality. The analyses included 3842 women in the Multiethnic Cohort (MEC) study of African Americans, Native Hawaiians, Japanese Americans, Latinos, and Caucasians, who completed a quantitative food frequency questionnaire, aged ≥50 yr at cohort entry, and diagnosed with primary invasive breast cancer following cohort entry (1993-2007). Hazard ratios (HR) and 95% confidence intervals (CI) were estimated from Cox proportional hazards regression with adjustment for known clinical and lifestyle factors. During a mean follow-up after diagnosis of invasive breast cancer of 6.2 ± 3.8 yr, there were 804 deaths including 376 breast cancer-specific deaths. The HR (95%CI) for all-cause and breast cancer-specific morality comparing the highest versus lowest tertiles were 1.03 (0.81-1.33) and 1.03 (0.71-1.50) for soy products and 0.99 (0.82-1.20) and 0.95 (0.71-1.28) for total isoflavones, respectively (Ptrend > 0.60 for all). There was limited evidence of differences by hormone receptor status, tumor stage, or ethnic group. Prediagnostic soy intake was unrelated to mortality in postmenopausal women. Our findings are consistent with the literature that soy consumption does not adversely affect breast cancer survival in women.Nutrition and Cancer 01/2013; 65(4):527-37. · 2.70 Impact Factor
- The Breast Journal 09/2012; 18(5):504-5. · 1.83 Impact Factor
Article: Erythrocyte membrane fatty acid composition, serum lipids, and non-Hodgkin's lymphoma risk in a nested case-control study: the multiethnic cohort.[Show abstract] [Hide abstract]
ABSTRACT: Composition of dietary fatty acid intake, which influences cytokine production, may contribute to the development of non-Hodgkin's lymphoma (NHL). Serum lipid levels may serve as biomarkers of inflammation associated with NHL risk. We conducted a case-control analysis (275 cases and 549 controls) nested within the Multiethnic Cohort Study (whites, Japanese Americans, Latinos, African Americans, and Native Hawaiians) to examine the association of prediagnostic, erythrocyte membrane phospholipid fatty acid composition, and serum cholesterol and triglyceride (TG) concentrations with the risk of NHL. Conditional logistic regression was used to calculate odds ratios (OR) and 95 % confidence intervals (CI) by tertiles of biomarker concentrations. Higher total saturated fatty acids (SFA) were associated with an increase in NHL risk (OR(T3 vs. T1) = 1.57 [95 % CI: 1.03-2.39]; p (trend) = 0.01), whereas no associations were detected for total n-3 or n-6 polyunsaturated fatty acids. Inverse associations were observed for total cholesterol (TC; OR (T3 vs. T1) = 0.51 [95 % CI: 0.35-0.74]; p ( trend ) < 0.0001) and high-density lipoprotein cholesterol (HDL-C; OR (T3 vs. T1) = 0.47 [95 % CI: 0.31-0.71]; p ( trend ) = 0.0001) but not for low-density lipoprotein cholesterol or TG. Adjustment for the use of lipid-lowering medication did not modify the results substantially. This prospective biomarker investigation offers supportive evidence for an adverse effect of higher erythrocyte membrane SFA levels on NHL risk, but preclinical effects cannot be excluded. Inverse relations between prediagnostic, circulating TC and HDL-C and NHL risk may be due to reverse causation or a result of protective actions of these lipids and lipoproteins.Cancer Causes and Control 08/2012; 23(10):1693-703. · 3.20 Impact Factor
Article: Higher alcohol intake may modify the association between mammographic density and breast cancer: An analysis of three case-control studies.[Show abstract] [Hide abstract]
ABSTRACT: Alcohol consumption and mammographic density are established risk factors for breast cancer. This study examined whether the association of mammographic density with breast cancer varies by alcohol intake. Mammographic density was assessed in digitized images for 1207 cases and 1663 controls from three populations (Japan, Hawaii, California) using a computer-assisted method. Associations were estimated by logistic regression. When comparing ever to never drinking, mean density was similar and consumption was not associated with breast cancer risk. However, within the Hawaii/Japan subset, women consuming >1 drink/day had a non-significantly elevated relative risk compared to never drinkers. Also in the Hawaii/Japan population, alcohol intake only modified the association between mammographic density and breast cancer in women consuming >1 drink/day (p(interaction)=0.05) with significant risk estimates of 3.65 and 6.58 for the 2nd and 3rd density tertiles as compared to 1.57 and 1.61 for never drinkers in Hawaii/Japan. Although these findings suggest a stronger association between mammographic density and breast cancer risk for alcohol consumers, the small number of cases requires caution in interpreting the results.Cancer epidemiology. 07/2012; 36(5):458-60.
Article: Prediagnostic circulating carotenoid levels and the risk of non-Hodgkin lymphoma: the Multiethnic Cohort.[Show abstract] [Hide abstract]
ABSTRACT: This analysis examined the association of non-Hodgkin lymphoma (NHL) with prediagnostic carotenoid levels, a marker for a diet rich in fruits and vegetables. We conducted a nested case-control study within the Multiethnic Cohort with 271 NHL cases and 538 controls matched on sex, ethnicity, location (Hawaii or Los Angeles), birth year, date and time of blood draw, and hours fasting before blood draw. Serum carotenoid levels were obtained by high-pressure liquid chromatography with photodiode array detection. Conditional logistic regression was used to calculate odds ratios (ORs) according to tertiles of serum carotenoids and trend tests using continuous variables. Higher total serum carotenoids (OR(T3 vs T1) = 0.66 [0.46-0.96]; P(trend) = .02), lycopene (OR = 0.54 [0.38-0.78]; P(trend) = .003), and α-cryptoxanthin (OR = 0.53 [0.36-0.78]; P(trend) = .003) were associated with a lower risk of NHL. For retinol (OR = 0.90 [0.61-1.33]; P(trend) = .04), a statistically significant inverse linear trend was detected. Risk estimates remained unchanged with adjustment for NHL risk factors and were similar in analyses stratified by sex and ethnicity; heterogeneity with NHL subtype was detected only for β-carotene. Other carotenoids, including α-carotene, β-carotene, lutein, β-cryptoxanthin, and zeaxanthin, showed no association with risk. These data provide support for a protective role of carotenoid-rich fruits and vegetables in the etiology of NHL.Blood 05/2012; 119(24):5817-23. · 9.78 Impact Factor
Article: Asian ethnicity is associated with a higher trunk/peripheral fat ratio in women and adolescent girls.[Show abstract] [Hide abstract]
ABSTRACT: Ethnic differences in body fat mass and distribution may develop in childhood and contribute to increased obesity-related disease risk among Asians. We used dual-energy X-ray absorptiometry (DXA) to evaluate adiposity measures among adult women and their adolescent daughters, who were of predominantly Japanese and white ethnicity. We obtained DXA whole body scans for 101 mothers aged 30 years or older and 112 daughters aged 10 to 16 years. The participants were classified as Asian, part-Asian, mixed/other, or white. As a measure of central adiposity, we calculated the trunk/peripheral fat ratio (TPFR). General linear models were used to evaluate differences in adiposity measures by ethnic category. In mothers, TPFR was significantly higher (P(trend) < 0.01) in Asians and part-Asians (1.38 ± 0.42 and 1.32 ± 0.51) than in mixed/others and whites (1.18 ± 0.27 and 1.09 ± 0.21). The trend was similar among daughters (P(trend) < 0.001), with respective values of 1.09 ± 0.18, 0.97 ± 0.17, 0.99 ± 0.16, and 0.87 ± 0.11. Among mothers, gynoid fat mass and peripheral fat mass were significantly lower in Asians than in whites, whereas none of the regional DXA adiposity measures differed by ethnicity in daughters. These results confirm previous reports of greater central adiposity in women of Asian ancestry and indicate that ethnic differences in adiposity are already present in adolescence.Journal of Epidemiology 03/2012; 22(2):130-5. · 2.11 Impact Factor
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ABSTRACT: One of the hypothesized protective mechanisms of soy against breast cancer involves changes in estrogen metabolism to 2-hydroxy (OH) and 16α-OH estrogens. The current analysis examined the effect of soy foods on the 2:16α-OH E(1) ratio among premenopausal women during a randomized, crossover intervention study; women were stratified by equol producer status, a characteristic thought to enhance the protective effects of soy isoflavones. The study consisted of a high-soy diet with 2 soy food servings/day and a low-soy diet with <3 servings of soy/wk for 6 mo each; estrogen metabolites were measured in 3 overnight urines (baseline and at the end of the low- and high-soy diet) using gas chromatography mass spectrometry for the 82 women who completed the study. Urinary isoflavonoids were assessed by liquid chromatography mass spectrometry. When applying mixed models, the 2:16α-OH E(1) ratio increased (P = 0.05) because of a nonsignificant decrease in 16α-OH E(1) (P = 0.21) at the end of the high-soy diet. Similar nonsignificant increases in the 2:16α-OH E(1) ratio were observed in equol producers (P = 0.13) and nonproducers (P = 0.23). These findings suggest a beneficial influence of soy foods on estrogen metabolism regardless of equol producer status.Nutrition and Cancer 02/2012; 64(2):307-14. · 2.70 Impact Factor
Article: Mammographic density, parity and age at first birth, and risk of breast cancer: an analysis of four case-control studies.[Show abstract] [Hide abstract]
ABSTRACT: Mammographic density is strongly and consistently associated with breast cancer risk. To determine if this association was modified by reproductive factors (parity and age at first birth), data were combined from four case-control studies conducted in the United States and Japan. To overcome the issue of variation in mammographic density assessment among the studies, a single observer re-read all the mammograms using one type of interactive thresholding software. Logistic regression was used to estimate odds ratios (OR) while adjusting for other known breast cancer risk factors. Included were 1,699 breast cancer cases and 2,422 controls, 74% of whom were postmenopausal. A positive association between mammographic density and breast cancer risk was evident in every group defined by parity and age at first birth (OR per doubling of percent mammographic density ranged between 1.20 and 1.39). Nonetheless, the association appeared to be stronger among nulliparous than parous women (OR per doubling of percent mammographic density = 1.39 vs. 1.24; P interaction = 0.054). However, when examined by study location, the effect modification by parity was apparent only in women from Hawaii and when examined by menopausal status, it was apparent in postmenopausal, but not premenopausal, women. Effect modification by parity was not significant in subgroups defined by body mass index or ethnicity. Adjusting for mammographic density did not attenuate the OR for the association between parity and breast cancer risk by more than 16.4%, suggesting that mammographic density explains only a small proportion of the reduction in breast cancer risk associated with parity. In conclusion, this study did not support the hypothesis that parity modifies the breast cancer risk attributed to mammographic density. Even though an effect modification was found in Hawaiian women, no such thing was found in women from the other three locations.Breast Cancer Research and Treatment 01/2012; 132(3):1163-71. · 4.47 Impact Factor
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ABSTRACT: Ethnic differences in breast cancer survival have been a long-standing concern. The objective of this article is to present relevant studies for all major US racial/ethnic groups including African-Americans, Latinos, Native Americans, Japanese-Americans and Native Hawaiians, and to discuss underlying causes of disparity. In comparison to Caucasian women, African-American women continue to experience the poorest breast cancer-specific survival of all ethnic groups in the USA. The prognosis for Latinos, Native Hawaiians and Native Americans is intermediate, better than for African-Americans but not as good as for Caucasians, whereas Japanese-American women tend to have better outcomes. The following possible contributors to the observed differences are discussed in detail: unfavorable distribution of stage at diagnosis due to low screening rates, limited access to care and treatment, tumor type, comorbidities, socioeconomic status, obesity and physical activity.Women s Health 11/2011; 7(6):677-87.
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ABSTRACT: One possible mechanism how nutritional factors may affect breast cancer risk is through an influence on estrogen levels. Nipple aspirate fluid (NAF) is thought to provide a more direct insight into hormonal influences on breast tissue than serum. The ability to produce NAF may be an indicator of breast cancer risk. The current analysis was conducted as part of a soy trial in 92 premenopausal women and evaluated the relation of usual dietary intake with NAF volume and the most predominant steroidal estrogens in NAF and serum at baseline. Estradiol (E(2)) and estrone sulfate (E(1)S) were assessed in NAF and E(2), estrone (E(1)), and E(1)S, in serum using highly sensitive radioimmunoassays. The statistical analysis applied multivariate, log-linear regression models. Intake of saturated fat and cheese (p = 0.06 for both) indicated a positive trend with NAF volume whereas isoflavonoid and soy consumption suggested inverse associations (p = 0.01 and p = 0.08). For estrogens in NAF, total fat and monounsaturated fat intake was positively associated with E(2) (p = 0.05 and p = 0.02) and in serum, alcohol intake was associated with higher E(1)S levels (p = 0.02). These findings suggest a weak influence of dietary composition on NAF production and estrogen levels in serum and NAF.Food & function. 11/2011; 2(11):665-70.
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ABSTRACT: On the basis of hypothesized protective effect, we examined the effect of soy foods on estrogens in nipple aspirate fluid (NAF) and serum, possible indicators of breast cancer risk. In a crossover design, we randomized 96 women who produced 10 μL or more NAF to a high- or low-soy diet for 6 months. During the high-soy diet, participants consumed 2 soy servings of soy milk, tofu, or soy nuts (∼50 mg of isoflavones per day); during the low-soy diet, they maintained their usual diet. Six NAF samples were obtained using a FirstCyte aspirator. Estradiol (E(2)) and estrone sulfate (E(1)S) were assessed in NAF and estrone (E(1)) in serum only, using highly sensitive radioimmunoassays. Mixed-effects regression models accounting for repeated measures and left-censoring limits were applied. Mean E(2) and E(1)S were lower during the high-soy than the low-soy diet (113 vs. 313 pg/mL and 46 vs. 68 ng/mL, respectively) without reaching significance (P = 0.07); the interaction between group and diet was not significant. There was no effect of the soy treatment on serum levels of E(2) (P = 0.76), E(1) (P = 0.86), or E(1)S (P = 0.56). Within individuals, NAF and serum levels of E(2) (r(s) = 0.37; P < 0.001) but not of E(1)S (r(s) = 0.004; P = 0.97) were correlated. E(2) and E(1)S in NAF and serum were strongly associated (r(s) = 0.78 and r(s) = 0.48; P < 0.001). Soy foods in amounts consumed by Asians did not significantly modify estrogen levels in NAF and serum. The trend toward lower estrogen levels in NAF during the high-soy diet counters concerns about adverse effects of soy foods on breast cancer risk.Cancer Epidemiology Biomarkers & Prevention 08/2011; 20(9):1815-21. · 4.56 Impact Factor
Article: Mammographic density and risk of breast cancer by adiposity: an analysis of four case-control studies.[Show abstract] [Hide abstract]
ABSTRACT: The association of mammographic breast density with breast cancer risk may vary by adiposity. To examine effect modification by body mass index (BMI), the authors standardized mammographic density data from four case-control studies (1994-2002) conducted in California, Hawaii and Minnesota and Gifu, Japan. The 1,699 cases and 2,422 controls included 45% Caucasians, 40% Asians and 9% African-Americans. Using ethnic-specific BMI cut points, 34% were classified as overweight and 19% as obese. A single reader assessed density from mammographic images using a computer-assisted method. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (95% CI) while adjusting for potential confounders. Modest heterogeneity in the relation between percent density and breast cancer risk across studies was observed (p(heterogeneity) = 0.08). Cases had a greater age-adjusted mean percent density than controls: 31.7% versus 28.5%, respectively (p <0.001). Relative to <20 percent density, the ORs for >35 were similar across BMI groups whereas the OR for 20-35 was slightly higher in overweight (OR = 1.69, 95% CI: 1.28, 2.24) and obese (OR = 1.62, 95% CI: 1.12, 2.33) than in normal weight women (OR = 1.49, 95% CI: 1.11, 2.01). Furthermore, limited evidence of effect modification by BMI of the OR per 10% increase in percent density (p(interaction) = 0.06) was observed, including subgroup analyses by menopausal status and in analyses that excluded women at the extremes of the BMI scale. Our findings indicate little, if any, modification by BMI of the effects of breast density on breast cancer risk.International Journal of Cancer 05/2011; 130(8):1915-24. · 6.20 Impact Factor
Article: Obesity and breast cancer survival in ethnically diverse postmenopausal women: the Multiethnic Cohort Study.[Show abstract] [Hide abstract]
ABSTRACT: Breast cancer survival has been found to be lower in obese women, but few studies have evaluated ethnic variations in this association. This study examined all-cause and breast cancer-specific survival by body mass index (BMI) in the Multiethnic Cohort (MEC) study for African American, Native Hawaiian, Japanese American, Latino, and Caucasian women. Female MEC participants free of breast cancer, aged ≥50 years at cohort entry, and diagnosed with primary invasive breast cancer during follow-up were included in the analyses (n = 3,842). Cox proportional hazards regression was used to estimate the effect of pre-diagnostic adult BMI (<22.5, 22.5-24.9, 25.0-29.9, ≥30 kg/m(2)) on the risk of mortality. Mean age at diagnosis was 68.8 years (range 50-89 years). During a mean follow-up of 6.2 ± 3.8 years after diagnosis, there were 804 deaths that included 376 breast cancer-specific deaths. After adjustment for breast cancer characteristics, including hormone receptor status, stage at diagnosis, and treatment, obese women had a higher risk of all-cause [hazard ratio (HR) = 1.54; 95% confidence interval (CI): 1.23, 1.91] and breast cancer-specific (HR = 1.45; 95% CI: 1.05, 2.00) mortality compared to women with high-normal BMI; however, being overweight did not affect survival. There was no evidence of ethnic differences in the BMI effect on all-cause (P (interaction) = 0.87) or breast cancer-specific (P (interaction) = 0.63) mortality. Our findings are consistent with the literature that maintaining moderate weight throughout adult life may be beneficial for breast cancer survival in women and this appears to hold for all ethnic groups.Breast Cancer Research and Treatment 04/2011; 129(2):565-74. · 4.47 Impact Factor
Article: The volume of nipple aspirate fluid is not affected by 6 months of treatment with soy foods in premenopausal women.[Show abstract] [Hide abstract]
ABSTRACT: Based on the hypothesis that soy food consumption may influence breast tissue activity, we examined its effect on the production of nipple aspirate fluid (NAF), a possible indicator of breast cancer risk. Of 310 premenopausal women screened, 112 (36%) produced at least 10 μL of NAF, the minimum for study participation. In a crossover design, we randomized 96 women to 2 groups who, in reverse order, consumed a high-soy diet with 2 soy servings/d (1 serving = 177 mL soy milk, 126 g tofu, or 23 g soy nuts) and a low-soy diet with <3 servings/wk of soy for 6 mo each separated by a 1-mo washout period. During each diet period, 3 NAF samples were obtained (baseline and 3 and 6 mo) using a FirstCyte Aspirator and 4 urine samples (baseline and 1, 3, and 6 mo) were analyzed for isoflavonoids by liquid chromatography tandem MS. Adherence to the study protocol according to 24-h dietary recalls and urinary isoflavonoid excretion was high. The drop-out rate was 15% (n = 14); 82 women completed the intervention. The 2 groups produced similar mean NAF volumes at baseline (P = 0.95) but differed in age and previous soy intake and in their response to the intervention (P = 0.03). In both groups, NAF volume decreased during the first 3 mo of the high-soy diet period and returned to baseline at 6 mo, but there was no effect of the high-soy diet on NAF volume (P = 0.50 for diet; P-interaction = 0.21 for diet with time). Contrary to an earlier report, soy foods in amounts consumed by Asians did not increase breast tissue activity as assessed by NAF volume.Journal of Nutrition 02/2011; 141(4):626-30. · 4.20 Impact Factor
Article: Mammographic density and hormone receptor expression in breast cancer: the Multiethnic Cohort Study.[Show abstract] [Hide abstract]
ABSTRACT: It is unclear whether mammographic breast density, a strong risk factor for breast cancer, predicts subtypes of breast cancer defined by estrogen receptor (ER) and/or progesterone receptor (PR) expression. In a nested case-control study, we compared the breast density of 667 controls and 607 breast cancer cases among women of Caucasian, Japanese, and Native Hawaiian ancestry in the Hawaii component of the Multiethnic Cohort Study. A reader blinded to disease status performed computer assisted density assessment on prediagnostic mammograms. Receptor status was obtained from the statewide Hawaii Tumor Registry. Tumors were classified into ER+PR+ (n=341), ER-PR- (n=50), ER+PR-/ER-PR+ (n=64), and unstaged/unknown (n=152). Mean percent density values were computed for women with more than one mammogram. Polytomous logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) while adjusting for confounders. Mean percent density was significantly greater for ER+PR+ but not for ER-PR- tumors compared to controls after adjusting for age: 37.3%, 28.9% versus 29.4%, respectively. The overall OR per 10% increase in percent density were similar for ER+PR+ and ER+PR-/ER-PR+ tumors: 1.26 (95% CI 1.17-1.36) and 1.23 (95% CI 1.07-1.42), respectively. However, percent density was not found to be a predictor for ER-PR- tumors (OR 1.00, 95% CI 0.84-1.18). The results did not differ by ethnicity, nor by menopausal status, parity, or HRT use. Our findings indicate that within a multiethnic population, women with higher breast density have an increased risk for ER+PR+ but not ER-PR- tumors.Cancer epidemiology. 01/2011; 35(5):448-52.
Top Journals
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John Hodgman Returns to SOLID SOUND 2013 to Present Comedy Lineup, 6/22
Comedian, author, television personality and historian John Hodgman returns to Solid Sound 2013 to present another hand-picked line-up of comedic talent on Saturday, June 22. The Solid Sound Festival, brainchild of the Chicago-based musical innovators Wilco, returns to the Massachusetts Museum of Contemporary Art (MASS MoCA) in North Adams on June 21-23. Tickets are on sale now at solidsoundfestival.com.
"I, John Hodgman, born of The Commonwealth of Massachusetts, am once again thrilled and honored to return to curate the comedy stage at Solid Sound."
"Solid Sound is not only one of our area's most important cultural exchange programs between Chicago and New England, but also it is simply the most vibrant, surprising, moving, and fun festival I have attended," said Hodgman, "and I can only hope to do for the comedy stage what Wilco has done for the festival as a whole: create exciting collisions among the most talented people in one of the most beautiful former factories on earth, while also rocking it down to the bones of the ground."
"To that end," he continued, "I have invited four incredible personalities to join me at MASS MoCA's Hunter Center on Saturday afternoon: my Daily Show colleague and senior Latino Correspondent, Al Madrigal; vocal impresario, TED speaker, and cosmic genius Reggie Watts; the incredibly smart and funny author, comedian, and Massachusetts native Jen Kirkman of Chelsea Lately; and Barack Obama, recently re-inaugurated president of the United States. And I am glad to report that three of these people have already said YES."
In other festival-related news, organizers are excited to launch two special culinary experiences to benefit MASS MoCA's charitable education programs. Both events take place on Saturday, and each will feature the food and spirits of the Berkshires, prepared by food artisans and sourced from farms and purveyors in the region. Tickets to either (or both) events are available now from MASS MoCA. These dining events are open only to festival attendees and admission to these events requires a pre-purchased festival ticket.
The first event of Berkshire-grown spirits and hors d'oeuvres takes place in an unrenovated 19th-century mill space at MASS MoCA from 5:00 pm to 7:00 pm on Saturday, June 22. This early evening tasting party (which overlooks the Courtyard D stage) will feature fresh seasonal ingredients from The Farms and small craft makers of the region. Cost is $90 per person and includes tapas-style food and drink served casually. Proceeds will benefit MASS MoCA's Kidspace and educational programs. $50 of the cost is tax-deductible.
About Author
- Anna Kendrick and Jeremy Jordan-Led THE LAST FIVE YEARS Movie to Hit Theaters, VOD on Feb 13
- Photo Flash: Key Art for GIRLS Season 4 Released
- 'BREAKING BAD (Original Score From The Television Series) Volume 2' Double LP Out Today
- President Obama Praises Icons Meryl Streep, Alvin Ailey and More at Medal of Freedom Ceremony
- NBCUniversal & Millennial Trains Project Announce New Partnership
- Official: Rachel McAdams, Taylor Kitsch & Kelly Reilly Join Cast of HBO's TRUE DETECTIVE
- Showtime to Air HOMELAND, THE AFFAIR Marathons this Weekend
- David Dobkin to Direct AMC's BADLANDS Pilot
- Cast of FINDING NEVERLAND to Perform on ABC's GOOD MORNING AMERICA on Thanksgiving
- NBC to Air NATIONAL DOG SHOW PRESENTED BY PURINA, 11/27

subset: commoncrawl


text:
November 27, 2014
The U.S. Department of Agriculture will open a four-week general signup for the Conservation Reserve Program on May 20.
Agriculture Secretary Tom Vilsack plans to make the formal announcement Saturday at the National Pheasant Fest and Quail Classic in Minneapolis. He says in a statement to The Associated Press that CRP was vital in later summer's drought. He says it protected sensitive land from erosion, while emergency haying and grazing on CRP lands provided critical livestock feed and forage.
Around 27 million acres are enrolled in the CRP, a voluntary program that pays farmers to keep environmentally sensitive land out of production, typically for 10 to 15 years. The goals are to improve water quality, control erosion and enhance wildlife habitat. Contracts on about 3.3 million acres expire Sept. 30.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or email@example.com.


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Madama Butterfly at the Met: Anthony Minghella's Dramatic Production Returns
* Additional fees apply.
The last date listed for Madama Butterfly was Friday January 24, 2014 / 7:30pm.
Currently at Metropolitan Opera House
The Met's Carmen: Bizet's Fiery Tale of Revenge
- Full Price:
- $87.50 - $142.50
- Our Price:
- $75.00 - $110.00
Acclaimed worldwide for her performances in the title role, Georgian mezzo-soprano Anita Rachveli...Learn More
Venue Details
The weather was sunny. I wore a jacket and tie.American Ballet Theatre 2014 Spring Season at the Met dress • Jun 09 2014 star this tip starred
I wore a dress..American Ballet Theatre 2014 Spring Season at the Met dress • May 28 2014 star this tip starred
Reviews & Ratings
Featured review from Goldstar Member
view more less of this review
It was beautiful! Gorgeous from start to end. Puccini's music, the sets, costuming, staging. A beautiful production of a wonderful classic.
star this review starred report as inappropriate
While I do love theater,i found out that operas are on a different level.It was quite long and you have to be very patient when reading the language which could be GERMAN,FRENCH OR POSSIBLY ITALIAN. Most people enjoyed the champagne.
star this review starred report as inappropriate
The production was terrific despite the cell phone in the row behind us. Not sure the acoustics are the best in rear orchestra -- have sat further up before and will try higher next time.
Approximate running time is 3 hours, 15 minutes with two intermissions.
Sung in Italian with Met titles in English, German, Italian and Spanish.
Rising tenor Bryan Hymel sings Pinkerton. Philippe Auguin conducts__.
Madama Butterfly__ is a co-production of the Metropolitan Opera, English National Opera, and the Lithuanian National Opera.
Photo: Marty Sohl/Metropolitan Opera


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Inn Pelagos - Skopelos
Stafylos - Skopelos1-877-662-6988
Looking for guest house accommodation in Skopelos? Why not try Pelagos!
This 3-star Stafylos, Skopelosguesthouse offers free Wi-Fi, an outdoor pool and dry cleaning/laundry services.
Staff can provide tour/ticket assistance. Other amenities include a garden.
We show TripAdvisor reviews for new Venere hotels that haven't been reviewed yet
Check Availability at Inn Pelagos
Inn Facilities at Pelagos
- Luggage room
- City tour
- Free parking
- Shuttle service
- Laundry service
- Garden
- Pets accepted
- Internet/Email services
- Outdoor swimming pool
- Baby sitter
Know before you go
- Cash transactions at this property cannot exceed EUR 1500, due to national regulations. For further details, please contact the property using information in the booking confirmation.
- This property offers transfers from the ferry terminal (surcharges may apply). Guests must contact the property with arrival details 48 hours prior to arrival, using the contact information on the booking confirmation.
- Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation.
Check-in: after 2 PM.
Check-out: before noon.
PolicyExtra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
National rating
For the benefit of our customers, we have provided a rating based on our rating system.
Room Details
Book your pet-friendly accommodation at Pelagos, offering 10 guest rooms with free Wi-Fi and air conditioning. Rooms open onto balconies. Well appointed kitchenettes offer a range of facilities, including refrigerators, stovetops and cookware/dishes/utensils, allowing you to save on dining expenses while you travel.
Guests can kick back at the end of a busy day and enjoy 14-inch televisions. Additional guest comforts include coffee/tea makers, soundproofing and free bottled water.
Private bathrooms are outfitted with showers, hair dryers and complimentary toiletries. Irons/ironing boards can be provided on request.
Accommodation Services
- Air conditioning
- Mini fridge
- Coffee and tea maker
- Soundproof rooms
- Ironing facilities on request
- Hairdryer in each room
- Wireless Internet access
- Cooking corner
- Terrace/Balcony
Distances from Inn PelagosStafylos Beach - 0.4 km / 0.3 mi
Valanio Beach - 0.9 km / 0.6 mi
Folklore Museum - 3.9 km / 2.4 mi
Museum of Photography - 4.1 km / 2.5 mi
Port of Skopelos - 4.1 km / 2.6 mi
Panormos Beach - 7.3 km / 4.5 mi
Milia Beach - 8.3 km / 5.2 mi
Kostas and Angela Mavrikis Museum of Alonissos - 12 km / 7.5 mi
Patitiri Beach - 12.1 km / 7.5 mi
Patitiri Harbour - 12.2 km / 7.6 mi
Port of Alonissos - 12.2 km / 7.6 mi
Glyfa Bay - 19.7 km / 12.3 mi
The preferred airport for Pelagos is Skiathos (JSI-Skiathos Island National) - 23.1 km / 14.3 mi.
Distances are calculated in a straight line from the property's location to the point of interest or airport and may not reflect actual travel distance.
Distances are displayed to the nearest 0.1 mile and kilometer.
Transportation services Guest House Pelagos
- Free parking
- Shuttle service


text:
An Iliad, Classic and Modern War Stories Inspired by Homer's Epic Poem
* Additional fees apply.
The last date listed for An Iliad was Sunday May 2, 2010 / 7:30pm.
Currently at Leo K Theatre at Seattle Rep
RuPaul's Drag Race Favorite Jinkx Monsoon in The Vaudevillians
- Full Price:
- $47.00
- Our Price:
- $24.50
After a sold-out off-Broadway run and an international tour, Seattle natives Jerick Hoffer (<em>R...Learn More
Venue Details
Share anything else here. Just start typing... It's general seating so come a little early to get the seat you want.Ernest Shackleton Loves Me info • Apr 28 2014 star this tip starred
I wore slacks..Ernest Shackleton Loves Me dress • Apr 28 2014 star this tip starred
Reviews & Ratings
Featured review from M Lindley
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A great night of theatre. Hans Altwies held the audience in the palm of his hand.
Quotes & Highlights
"An Iliad proves an ancient tale can still be meaningfully and well-told." —The Seattle Times
"It's a brilliant tour-de-force, unveiling an Iliad you've likely never seen before." —The Sun Break
"The Seattle Rep has capped off what has already been a stellar season with yet another gem." —Broadway World
"…the play takes flight and Hans Altwies as the storyteller of Homer's sweeping saga of gods, heroes, and war starts to weave the tale and draw you in." —Seattle Gay Scene
Created by Denis O'Hare and Lisa Peterson
Directed by Lisa Peterson
A new take on one of history's most famous and exciting tales, _An Iliad pulls from Homer's sweeping fable of gods, heroes and the Trojan War, and weaves his timeless legends with modern stories of war and revenge. Created by acclaimed Broadway actor Denis O'Hare and director Lisa Peterson and starring Seattle actor Hans Altwies (_The Seafarer, The Three Musketeers), this captivating theatrical experience takes audiences on an unforgettable trip celebrating the art of storytelling.


text:
|Sign Up Box Is Located On Bottom Right of Homepage. Enter any new email address and receive your exclusive coupon code or printable coupon for online & in store shopping!
Expires: 01/31/15
|Online: 30% Off Prices As Marked
Stores: 30% Off Discount Give at Checkout
Add 2+ Knit Tops (of Equal or Lesser Value) to Cart - At Online & Store Checkout, Each 2nd Item Is FREE
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Hands On with The MINI_Motion driving shoe
It's taken months but I finally got my hands on a pair of the MINI_Motion driving shoes – although not my own. After coming up short trying to find size 12 or 13 (no easy task!) I figured I'd surprise my wife with a pair and write a little about them first hand. She's happy, I'm happy, you get a review – great plan I'd say!
The first thing you notice about the shoes once you see them is the simplicity of the upper design. There are no laces, just some spandex like material and a piece of leather that wraps over it and attaches to the outside with one small metal buckle. The upper is made entirely out of leather save for the rubber pull in the back (which is the only place you'll see a MINI logo). The stitching of the Puma logo is grey and not gold like as it appears on the MINI_Motion website.
The mid-sole is just as simple with no PVC foam at all – just a piece of leather as cushioning. This is how the Puma Speed Cat is built as well – to some degree the shoe that the MINI_Motion shoe is based on. The key differences between it and the Speed Cat's mid-sole is the sole pattern from the and the piece of rubber that wraps around and up the shoe on the outside front (the part that says "Motion").
The lycra removable boot is less usable than one would hope. The upper of the boot is very thin and breathes well but wearing it it seems like an unnecessary step much of the time. Further the bottom of the boot has no grip whatsoever. It's usage is fairly limited considering you'd probably tear up the bottom wearing it outside. The bottom is made of some type of synthetic material similar to the anthracite material found in the BMW 3 series Performance Package.
While it's a fairly narrow shoe overall my wife likes the fit and overall comfort. It should be perfect for it's intended sport – motoring. However it's worth nothing that they are snug with the boot and a bit more comfortable without.
The MINI_Motion driving show is available in both Black and Grey at MINI_Motion.com or at select Puma retailers worldwide for $150. This particular pair was found in a California Puma outlet for the unheard of sale price of around $30 – although sizes were limited.
Written By: MF Staff
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text:
Business type: Technology - Manufacturer ×
Keyword: waste treatment ×
Industry: Manufacturing, Other ×
Location: Canada ×
Location: Yukon ×
Lenntech Water Treatment
based in Delft, NETHERLANDS
Lenntech Water Treatment is a manufacturer and solutions provider for industrial water purification. Lenntech always offers its clients a spectrum of environmentally friendly technologies for each issue. Each proposed technology is compared both technically and economically with each other. Lenntech supplies water and air treatment systems for disinfection, filtration, ...
O3 Greentech
based in Surat, INDIA
We are introduce our self as a technology and performance based State of Art Ozone Generator manufacturer, water and waste water treatment solution provider.Ozone widely used in Oxidizing & Anti Microbial agent used in water Treatment, Waste Water Treatment, Sewage Treatment, Swimming Pool, Pharmaceutical, Chemical, Pulp & Paper, Food Processing, Poultry Farm, Hotels & ...
Terragon Environmental Technologies Inc.
based in Montréal, QUEBEC (CANADA)
Terragon develops and commercializes innovative technologies and practices needed to enable habitats to treat their waste locally and safely in order to recover valuable resources to be reused at the site where waste is generated. Terragon researches and engineers highly innovative waste treatment systems which anyone can operate safely, economically and without special ...
High Temperature Technologies Corp. Canada
based in Chateauguay, QUEBEC (CANADA)
Waste to Energy Conversion Systems. High Temperature Technologies Corp. is a leader in design, development and manufacturing of the plasma based waste treatment solutions. High Temperature Technologies Company is a privately-owned firm based in Montreal, Canada. It offers environmentally-friendly solutions for waste treatment and disposal. Its highly innovative technology ...
Groupe Vauché
based in Sedan, FRANCE
As a designer of process and a manufacturer of equipments dedicated to the environment, the Groupe Vauché Europe realizes complete units of solid waste treatment, such as selective collection units, mechanical-biological treatment plants, biogas units, valorization of clinkers, industrial waste and production of alternative fuels. Our asset lies in the complete mastery of ...
Super-F Fragrance Inc.
based in L`Assomption, QUEBEC (CANADA)
Super-F Inc. is established in Quebec, in l`Assomption, Canada. We are specialists in manufacturing products for neutralizing odors and gases. Our new technology was discovered by Mr. Paul Arsenault in 1996, results of many years of researches. Super-F Technology is made of complex compounds of natural extracts and synthesis products. Injecting our products in the course ...
DANTECH - Danish Technology Center
based in Gilleleje, DENMARK
DANTECH - Danish Technology Center deliver complete wastewater treatment systems and solutions to the food Industry. With Compact green technology systems within filtration, separation, oxidation, flotation, and Centrifugation, DANTECH has proven a market leader in industrial wastewater treatment.
PRECIMECA Environnement
based in Toulouse, FRANCE
PRECIMECA designs and manufactures waste shredders since 1972. Specialists of solid waste shredders, industrial waste shredders, and leaders in tyre shredders field with installations all over the world to make Tyre Derived Fuel (TDF) or granulates (recycling rubber from tyres).
Toro Equipment S.L.
based in La Cistérniga, SPAIN
Toro Equipment is one of the principal companies specializing in the design and construction of machinery for the treatment and waste water treatment. The expansion of his activities has needed the search of new markets, up to forming a commercial international structure with presence in diverse countries. Our Equipments are manufactured to the highest standards and ...
Microbac Ltd
based in Consett, UNITED KINGDOM
Microbac designs and supplies Wastewater Treatment Plants of all sizes for industrial effluents and sewage. Primarily based around Microbac`s own technology in submerged aerated fixed-film bioreactors or membrane bioreactors and adapted biological cultures, the treatment systems offer many advantages over conventional biological plants, including small footprint, rapid ...


text:
Marina Information
Late Fees Apply QuarterlyLate fees are due for any 2014 Assessment payments made after midnight Central Time on January 31, 2014. Pleaseinclude an additional $75 per lot or unit when you make your payment.
The City of Lago Vista reminds you that we are at
Stage 2b Mandatory Water Restrictions.
The City is increasing its enforcement efforts, so be sure you know the rules to avoid a fine. Click here to see the current watering rules.
Board of Directors Election Information Available Click here to visit the Member Home Page for information on the three new LVPOA Directors.
12/02/2014 - 01:00 PM to 03:00 PMBlue Santa Benefit[more]
This site is provided by Lago Vista Property Owners Association


text:
Select () or exclude () categories to narrow your recipe search.
As you select categories, the number of matching recipes will update.
Find exactly what you're looking for with the web's most powerful recipe filtering tool.
1/2 Photos of Top Notch Oatmeal Macaroons
Prep Time:
Cook Time:
20 mins
17 mins
a recipe given to me by a friend that won 1st place at a baking contest.
Serves: 48
Units: US | Metric
Serving Size: 1 (35 g)
Servings Per Recipe: 48
Every recipe, menu, tip and how-to is right here, at your service.


text:
NEW YORK (CNNMoney.com) -- Ford Motor reported its first full-year profit since 2005 and said it expects to be profitable again in 2010.
The automaker, which has outpaced the turnaround at both its domestic and some overseas rivals, said Thursday that it earned $2.7 billion in 2009. The company was helped by special items that added $2.6 billion to its bottom line during the year.
But even without that assistance, Ford (F, Fortune 500) essentially broke even after taxes. That's far better than the loss of 31 cents per share that analysts had forecast for 2009. Ford lost $7.3 billion, or $3.20 a share, on that basis in 2008.
Despite the good news, Ford shares fell about 1% Thursday morning.
For the fourth quarter, the company reported a net profit of $868 million. Its operating income of $1.6 billion, or 43 cents a share, was a dramatic improvement from the operating loss of $3.3 billion, or $1.40 a share a year earlier. This also easily topped forecasts of a 26 cent per share operating profit.
Ford's automotive operations earned $1.1 billion in the quarter. The company also said auto operations added $3.1 billion to its cash flows in the quarter, a remarkable turnaround after drawing down the company's cash reserves for years.
Profits ahead. Ford also said it now expects to be profitable on a pre-tax basis in 2010. Previously, the company had said it expected profits to return in 2011 but that it was not yet willing to predict it would make money this year.
"While we still face significant business environment challenges ahead, 2009 was a pivotal year for Ford," said Ford president and CEO Alan Mulally in the company's statement. "Our progress has helped us gain market share in most of our major markets."
One of those markets was the United States. Ford's share rose to 16.1% from 15% in 2008, its first increase since 1995.
Still, auto sales plunged around much of the world in 2009. Ford's global vehicle sales fell 11% to 4.8 million, causing the company's overall revenue for the year to slide 14% to $118.3 billion.
But auto sales were much better in the fourth quarter, jumping 26% compared to a year ago to 1.4 million vehicles. Total revenue rose 22% to $35.4 billion, easily beating forecasts of $32.6 billion.
The company said it expects the sales momentum from the end of 2009 to continue into this year. And it has increased its first quarter production targets by 42% from year-ago levels.
Ford chief financial officer Lewis Booth said the bounce in sales during the last two months of the year gave the company more confidence going into 2010.
"We feel just a little more positive that the green shoots are still there, that they haven't shriveled up," Booth said.
Ford was helped last year by federal bailouts and bankruptcies at its two major domestic rivals, General Motors and Chrysler Group, actions that drove many customers who prefer domestic automakers to Ford.
"It's amazing how quickly these things can change," said Mike Boudreau, director of Michigan turnaround firm O'Keefe & Associates. "By avoiding bankruptcy, they told everyone out there -- its employees, its suppliers, its customers -- that Ford stands behind its obligations and its products."
Gaining on the imports. Ford also has enjoyed bigger gains than any of its Japanese rivals, and it begins 2010 with Toyota Motor (TM) being hit by a recall of more than 5 million vehicles in the United States and Europe and a halt in sales of its best-selling U.S. models due to problems with a sticking gas pedal.
Mulally said it is too soon to say how much Ford will benefit from Toyota's problems, but he said he's pleased with the gains the company has been making with customers who formerly bought import brands.
"It depends on how this all plays out and how fast Toyota gets this behind them," he said in response to a question during a conference call. "It's really an opportunity for our products to be viewed again."
There was a bit of bad news for Ford Thursday though, as a joint venture it has in China has halted production of a commercial van it builds there because of concerns it could be hit by the same gas pedal problems as Toyota.
But Ford's problem affects less than 2,000 vehicles in China, and so far no problems have been reported by customers, said Mulally. He said the halt in production is a precaution because the company uses the same supplier for that part as does Toyota.
|% Change
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The European Parliament has voted to break up Google and weaken its dominance across the region. More
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text:
Awards Evening Tickets on Sale as Player of the Year Voting Opens
Tuesday, 16th Apr 2013 16:34
Tickets are still available for this year's Supporters Club Player Awards Evening, which will be held in Legends Bar on Saturday 27th April from 6.30pm to 12am. The first team squad, management and new joint-MDs Ian Milne and Jonathan Symonds will be attending and the Player of the Year award – for which voting has now opened - and a host of other trophies will be handed out.
The event provides a great opportunity to have photographs taken with the players and coaching staff and to collect autographs.
Presentations will be made during the evening to all the players who have made their debut during the season, the Academy Player of the Year and the Supporters Player of the Year, along with a special presentation to the Young Fan of the Year.
Tickets cost £20 including a buffet and can be obtained from Liz Edwards by emailing firstname.lastname@example.com or by phoning 07968 876504.
Alternatively, write to Irene Davey at 10 Lambeth Close, Ipswich, IP1 4DX (please enclose a cheque made payable to Ipswich Town Football Club Supporters Account and a SAE).
Voting for the Player of the Year award has opened online at the Supporters Club website here. This will continue until Friday 26th April.
Voting will also take place outside Portman Road prior to the home game against Birmingham City on Saturday 27th April.
As in previous years the Supporters Club is looking for helpers to collect votes around the ground. If you would like to assist in the voting please contact Elizabeth Edwards at the email address and phone number above.
Get two free £10 bets on Charlton Athletic v Ipswich Town (or other matches) by opening a new account at William Hill. Place an initial bet of a minimum of £10 and William Hill will give you two £10 bets. You must enter the promotional code "F20" when signing up as a new customer.
Please report offensive, libellous or inappropriate posts by using the links provided.
You need to login in order to post your comments
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Happy Dappy Doo by paulthebluealien
Right, let's cut straight to the chase. There are far too many people posting happy stuff on this forum; it's annoying me so I'm going to bring us all crashing back down to earth by being negative.
Isn't This Lovely? by Luka
We have a headache, though we don't need paracetamol. The headache is one of selection. Who to put in? Where? How do we line up?
Mick McCarthy: Man-Management 101 by everhopeful
It's October 2012. We knew it would happen the second Stephen Henderson's error saw Derby go in level at the break.
Time for a Change? by therealtractorboy
For the last seven years of my life I have made the trip to see Ipswich Town every other Saturday. Every August, I hope. Every Saturday at 2:55, I hope. This season, for a very much welcome change, these hopes may not be shattered.
BogeyLand by paulthebluealien
Ladies, gentleman and Ipswich Town fans everywhere may I present to you bogeyland. Which for all you cryptic geniuses out there means only one thing.
Ipswich Town Polls
[ Vote here ]
TWTD.co.uk Story Archive


text:
Wolves Win in Vegas
The Timberwolves ended Summer League play with a 97-91 win over the Grizzlies. Mike Harris had 22 points and 12 rebounds for the Wolves, who went 4-and-1 during their stay in Las Vegas. Kammron Taylor …23 Jul 12
Local News, Multimedia, Sports - The Local Connection
Wheeler Dealer
The Timberwolves ended Summer League play with a 97-91 win over the Grizzlies. Mike Harris had 22 points and 12 rebounds for the Wolves, who went 4-and-1 during their stay in Las Vegas. Kammron Taylor …23 Jul 12
Derrick Williams scored 23 points as the Timberwolves defeated the Cavaliers, 78-65. Coby Karl added 18 points off the bench for Minnesota, which is 2-and-1 in Summer League action. The Wolves take on the D-League …20 Jul 12
The Portland Trail Blazers have matched the offer sheet the Minnesota Timberwolves made to restricted free agent Nicolas Batum [[ buh-TOOM ]]. The Blazers matched the offer reported to be for more than $45-million over …19 Jul 12
Wes Johnson scored 24 points as the Wolves fell to the Bobcats, 81-78. Derrick Williams added 17 points and seven rebounds but turned the ball over six times in the loss. The Wolves continue summer …18 Jul 12
The Timberwolves notched a 73-64 win over the Clippers in their Summer League opener last night. Derrick Williams collected 15 points and nine rebounds for the Wolves. Wes Johnson scored a team-high 16 points in …17 Jul 12
The Timberwolves begin Summer League action in Las Vegas tonight. They play the Clippers. Minnesota will be back on the floor the following day against Charlotte. Play in Las Vegas ends on July 22nd. T'wolves …16 Jul 12
The much-anticipated 2012 NBA Draft took place last night at the Prudential Center in Newark, New Jersey. The Minnesota Timberwolves took Robbie Hummel with the 58th overall pick in the second round. The Wolves traded …29 Jun 12
The Timberwolves released their Summer League schedule yesterday. The Wolves will begin Summer League play against the Clippers on July 16th. The Wolves will also face the Bobcats, Cavs, the D-League All-Star team and the …15 Jun 12
KNUJ's FFA Broadcast crew of Larry Baumgardt, and Jim Bartels bring years of broadcast and FFA expertise to the airwaves each year from both the National FFA Conventions. Stay tuned for interviews and updates from …


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The Press Newspaper
The Press Newspaper
Twenty-three students took advantage of SAP this year. Of those, eight students earned enough credits to graduate from high school and five students completed two years' worth of work in one year.
The program provides an educational alternative to the traditional classroom. Students who are credit deficient complete all their courses online. Students hear a variety of speakers and take numerous field trips. They also participate in physical education, counseling and life skills development. Personal growth, self-awareness, interpersonal skills and responsibility for one's behavior are stressed throughout the program.
Some of the highlights of the year were a tour of Guardian Industries in Millbury, a presentation by Captain Steve Levorchick on the Ottawa County Special Response Team, completion of a first aid/CPR course, and participation in Tiger Woods' "The First Tee" golf program at the Oak Harbor Golf Club.
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Christmas spending
Are spending more, less or the same amount this year for Christmas?
The poll results are hidden from public viewing.
1363891448 [{"id":"27","title":"More","votes":"0","pct":0,"type":"x","order":"1","resources":[]},{"id":"28","title":"Less","votes":"2","pct":66.67,"type":"x","order":"2","resources":[]},{"id":"29","title":"The same","votes":"1","pct":33.33,"type":"x","order":"3","resources":[]}] ["#194e84","#3b6b9c","#1f242a","#37414a","#60bb22","#f2babb"] sbar 160 160 /component/communitypolls/vote/12-christmas-spending No answer selected. Please try again. Thank you for your vote. Answers Votes


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You can now filter search results with text. Example: "person: john" will search only person pages for "john".
"I'm Cupid, stupid, and I'm going to kill everyone Arrow doesn't like. That'll make him love me, right? RIGHT?!"
Spinning out of Spider-Verse, Jessica Drew is on a mission with some other Spider-Folk. Even if you've been reading the other Spider-Verse titles, there will be some confusion.
Tony Stark's been conspicuously MIA since the title jumped forward. Time to see what he's been up to!
Character »
Sir Ystin appears in 48 issues.
Described as a "medieval playboy inventor", Al Jabr is a member of the Demon Knights.
Ali Ka-Zoom, as a child, was a member of Newsboy Army. Later a homeless aging wizard, he would guide the Seven Soldiers' mission.
The most cheerful member of the Knights of the Broken Table.
Caradoc is a member of the Knights of the Round Table.
One of the most notorious of Hell's demons, Etrigan's soul was merged with the body of a human man, Jason Blood, who calls upon the demon's terrifying power to fight the forces of darkness.
Amazonian warrior in exile who joined the Demon Knights.
Once a patient in a mental hospital, Galahad wanders Star City forest after the destruction of a major part of the city as a knight assisting Green Arrow.
One of the Knights of the Broken Table. He is always attended by two hawks.
FBI metahuman specialist.
A free spirit, wandering vigilante, and a master archer, the mysterious Horsewoman is a reluctant member of the Demon Knights.
Jason o' the Blood was a nobleman of the 6th century Camelot during the time of King Arthur. When the wizard Merlin summoned the demon Etrigan, he bonded him to Jason as a means of containment. Though they have been bonded for centuries, the two often come to blows with each other.
Leader of the Knights of the Broken Table. He was killed by Neh-Buh-Loh and later consumed by his spider-mare.
Madame Xanadu focuses her occult sensitivity through her Tarot cards. Her actual powers in terms of matters of the soul are somewhat limited - she is only allowed to advise.
Merlin once used the Holy Grail to bring Ystin back to life.
Friend of Ystina. She was abducted by Gloriana Tenebrae and turned into shapeshifting creature after she spent 43 days at Summer's End.
Blind member of the Knights of Broken Table. He possesses senses unknown to ordinary men.
One of the Knights of the Broken Table. He was killed during battle with the Sheeda.
He's been witness to humanity's growth from the dawn of time, and his desire to control mankind has led him into conflict with many heroes of the DC Universe. He is Vandal Savage, the immortal tyrant!
Winged intelligent horse of the Shining Knight and named as one of the Seven Imperishable Treasures.
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rolf westgard
Recent Comments
African American students are disciplined because they misbehave more. It is that simple. Young African American males are in the judicial system in great numbers because they commit more crimes.
They enter elementary school unable to compete and either drop out or fail. They can't compete with children who have two parents who read to them, computers in the home, parents who speak correct English, etc.
We need a strong pre school program to make up for these deficiencies. By...
Sea level rise was rapid as the Wisconsin Glacier(last one) melted. The rise has now slowed to about one inch per decade.
A problem for some low lying areas, but not the catastrophe the article suggests. Warren Buffett, CEO of some big casualty insurance outfits, notes that their rates are stable because there is no increase in unusual weather events. Hurricanes were pure profit in the past decade with no Force 3 or stronger hitting the US. Most of Force 1 Sandy's losses were on...
That's why Buffett only insures them through the government funded flood insurance program. Again sea level rise has slowed to one inch per decade.
No increase in overall tornado intensity. Hurricanes like Camille and Andrew stronger than anything recent. Current drought in West pales compared to longer severe droughts in past few thousand years. No unusual floods.
Ice sheets by definition are on water. When they melt no increase in sea level. Recent study in journal Science showed that net melt from Antarctica and Greenland raised sea level one inch in forty years.
Relax people and don't sell your winter coat.
My wife and I enjoy reading the PP each morning from the front page to the last. My only complaint, as an old guy with a bad back, is having to lug the recycling bin, filled with Sunday ads, to the curb.
This ming can be done safely as was done in Wisconsin and elsewhere. It's time for the dirt to fly.
This is a really good report on a very important issue. There is no miracle substitute for those bees.
This effort needs to start in pre school to have a chance.
is for a strong pre school program. By the time youths are in those residential treatment facilities, it is too late.
There is a stiff carbon tax, but that is not very popular. Slogans and renewables are easier.
We could also stop breathing. Each human exhales a few pounds of CO2/day, or nearly half a ton of it annually.
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Review: Pseudoephedrine and Cipro Xr
Summary: drug interactions are reported among people who take Pseudoephedrine and Cipro Xr together.
This review analyzes the effectiveness and drug interactions between Pseudoephedrine and Cipro Xr. It is created by eHealthMe based on reports of 89 people who take the same drugs from FDA and social media, and is updated regularly.
You are not alone: join a mobile support group for people who take Pseudoephedrine and Cipro Xr >>>
What are the drugs
Pseudoephedrine hydrochloride (latest outcomes from 674 users) has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion.
Cipro xr (latest outcomes from 11 users) has active ingredients of ciprofloxacin; ciprofloxacin hydrochloride. It is often used in urinary tract infection.
On Nov, 27, 2014: 89 people who take Pseudoephedrine Hydrochloride, Cipro Xr are studied
Drug combinations in study:
- Pseudoephedrine Hydrochloride (pseudoephedrine hydrochloride)
- Cipro Xr (ciprofloxacin; ciprofloxacin hydrochloride)
Drug effectiveness over time :
Most common drug interactions over time * :
|< 1 month
|1 - 6 months
|6 - 12 months
|1 - 2 years
|2 - 5 years
|5 - 10 years
|10+ years
|not specified
|Injection Site Pain
|Throat Tightness
|Pulmonary Embolism
|Upper Respiratory Tract Infection
|Abdominal Pain
|Sinus Disorder
|Tooth Disorder
|Biliary Dyskinesia
|Oedema Peripheral
|Rotator Cuff Syndrome
|Osteonecrosis Of Jaw
|Vitreous Detachment
|Tricuspid Valve Incompetence
Drug effectiveness by gender :
Most common drug interactions by gender * :
|Colon Adenoma
|Chest Pain
|Cardiac Disorder
|Tooth Disorder
|Pain In Extremity
|Rotator Cuff Syndrome
|Groin Pain
|Oedema Peripheral
|Gastrointestinal Disorder
|Osteonecrosis Of Jaw
|Abdominal Pain Upper
|Vitreous Detachment
|Decreased Appetite
|Tricuspid Valve Incompetence
|Crohn's Disease
Drug effectiveness by age :
Most common drug interactions by age * :
|Flank Pain
|Gallbladder Disorder
|Rotator Cuff Syndrome
|Gastrointestinal Disorder
|Tricuspid Valve Incompetence
|Musculoskeletal Chest Pain
|Decreased Appetite
|Bile Duct Stone
|Tooth Disorder
|Hip Fracture
|Colon Adenoma
|Deep Vein Thrombosis
|Back Pain
|Crohn's Disease
|Cholecystitis Chronic
|Abdominal Pain Upper
|Foot Fracture
|Groin Pain
|Musculoskeletal Pain
|Upper Limb Fracture
|Abdominal Pain Upper
|Hepatic Cyst
|Oedema Peripheral
|Fungal Infection
|Multi-organ Disorder
|Left Ventricular Hypertrophy
|Wound Infection Staphylococcal
|Pain In Extremity
|Weight Decreased
* Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you take Pseudoephedrine and Cipro Xr?
- Personalize this study to your gender and age
- Write a review: share your experience of taking Pseudoephedrine and Cipro Xr
- Ask a question: ask patients like you a question
- Subscribe the study: get notified of updates
- Post a comment: or see what other people said about the study
You are not alone! Join a related mobile support group:
- support group for people who take Pseudoephedrine and Cipro Xr
- support group for people who take Cipro Xr
- support group for people who take Pseudoephedrine Hydrochloride
Latest outcomes in real world:
- Cipro Xr reported by 11 people (updated 2 weeks ago)
- Pseudoephedrine Hydrochloride reported by 674 people (updated 2 days ago)
Can you answer these questions (Ask a question):
- Hallucinations and skin thas red and hurts
(Asked by a 46 year old woman who has Hallucinations.skin Thats Red Like A Sun Burn And Mouth Blisters, and takes Hydrochlorothiazide, Sudafed, Levothyroxine Thyroid)
I am having horrable hallucinations.manic episodes because i slam on the brakes to avoid people or animals that are not there.i feel like im going to razy.high bood pressure, heavy breathing and anxiety.my face and body have spoys that are like a sun burn and blisters in my mouth.emergency room accu ...
- Wondering if dexilant is causing my problem
(Asked by a 61 year old man who has Do Not Urinate Much In Evening, Have To Urinate 3 Or 4 Times At Night, and takes Methocarbamol And Aspirin, Pseudoephedrine Hydrochloride, Ibuprofen, Rosuvastatin Calcium, Atenolol, Ramipril, Amlodipine, Dexilant )
have had my prostate checked by urologist and prostate is slightly enlarged but not enough to cause problems.urinary track ok,bladder ok etc. drank a liter of water and bladder emptied ok in test. seem to urinate good after consuming coffee or beer but lately having more whiskey than beer. when I ...
- Could this drug cause periodontal bone loss, bone loss around teeth
(Asked by a 64 year old man who has Periodontal Bone Loss, Bone Loss Around Teeth , and takes Guaifenesin, Pseudoephedrine Hydrochloride, Turmeric, Trazodone Hydrochloride, Fluoxetine, Celexa, Gabapentin, Omeprazole, Pantoprazole, Pentoxifylline, Garcinia Cambogia, Carbamazepine, Tamsulosin, Lisinopril, Venlafaxine Hydrochloride, Flunisolide)
Do you suffer from periodontal bone loss or periodontal disease, or bone loss around teeth after taking this drug? Are your sodium levels low after taking this drug? I am a dentist and keep my teeth plaque free, but have had periodontal bone loss for which, I believe, must be drug related.
- Can i take saphris with sudafed and benadryl
(Asked by a 25 year old man who has Bipolar Plus Cold And Flu And Cough, and takes Saphris, Sudafed, Benadryl)
Is it ok to take sudafed and Benadryl cold and flu tablets with saphris bipolar tablets?
- How do i become a part of this study?
(Asked by a 44 year old woman who has Stroke, and takes Sudafed 12 Hour)
I was taking Sudafed and had a stroke took Sudafed again and had a second stroke
More questions for: Cipro Xr, Pseudoephedrine Hydrochloride
You may be interested at these reviews (Write a review):
- Skin burning sensation with delsym
(Posted by a 36 year old woman who has Skin Burning Sensation, and takes Wellbutrin Sr, Sudafed)
I had been sick for about a week and had been taking Sudafed every 4-6 hours for congestion for the past couple of days. I also take wellbutrin SR daily as an antidepressant. I started taking the suspension formula of Delsym 12 hour release about 24 hours previously (so I had already had two doses ...
- Bad nosebleed (sudafed related?)
(Posted by a 48 year old man who has Rhinitis Medicamentosa, and takes Phenylephrine Hydrochloride, Ocuclear, Flonase, Sudafed 12 Hour, Zicam)
I have the rhinitis as a result of rebound syndrome from using nasal sprays for years. I use the Flonase to somewhat alleviate the need for the over-the-counter sprays (first two drugs listed). In spite of that, I rarely, if ever, have nosebleeds. I also rarely, if ever, get colds. However, yesterda ...
More reviews for: Cipro Xr, Pseudoephedrine Hydrochloride
Complete drug side effects:
Pseudoephedrine Hydrochloride side effects reported by 186 people (updated 1 week ago)
Cipro Xr side effects reported by 8 people (updated 2 months ago)
Pseudoephedrine Hydrochloride side effects reported by 186 people (updated 1 week ago)
Cipro Xr side effects reported by 8 people (updated 2 months ago)
On eHealthMe, Pseudoephedrine Hydrochloride (pseudoephedrine hydrochloride) is often used to treat nasal congestion. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Pseudoephedrine hydrochloride is used in:
Other drugs that are used to treat the same conditions:
- Pseudoephedrine hydrochloride alternatives:
Recent related drug studies (Check your drugs):
- A study of drug interactions between Valerian, Melatonin, Aleve, Ibuprofen, Excedrin, Sudafed, Xanax for a patient with Insomnia, Pain - Back, Backaches And Stress, Headache, Sinusitis Chronic, Anxiety. The patient has Ankle Swelling
Comments: I'm having oral surgery in a couple of days & dentist gave me xanax to take for the anxiety. I tried one pill Friday night to see how it would affect me & noticed the swelling Saturday
- A study of side effects of Sudafed 12 Hour for a patient with Sinusitis. The patient has Laryngitis (inflammation of the larynx)
Comments: If I take Sudafed for a week or more then stop the med it seems like it get laryngitis
- A study of drug interactions between Pepcid, Sudafed, Aspirin, Cymbalta for a patient with GERD, Ear Congestion, Blood Thinner, Depression. The patient has Cough
Comments: Coughing is severe often to the point that things go black and there is a ringing in my ears. I have never passed out, though I often think I may. I have allergies and my coughing onset is usually due to aspiration of food drink or sinus drainage. Sometimes It begins with a sharp tickle in my lar ...
- A study of drug interactions between Bupropion Hydrochloride, Pseudoephedrine Hydrochloride, Levothyroxine Sodium, Zolpidem Tartrate, Clonazepam, Albuterol Sulfate, Advair Diskus 500/50 for a patient with Major Depression, Copd, Thyroid Disorder, Chronic Insomnia. The patient has Chronic Depression
Comments: Had Turp 4.5 yrs ago, have had retrograde ejaculation since procedure. Bupropion, Take two 200mg in morning and one 200mg in the evening Use nebulizer 4 or more times per day. Recently changed to clonazepam, had been on alprazolam 1 mg 3 times a day.
- A study of drug interactions between Tylenol, Sudafed 12 Hour, Claritin Reditabs for a patient with Sinus Pain, Nasal Allergies, Allergies. The patient has Sinusitis
Comments: Have sinus pain in eyes nose and gums. Taking a mix of Claritin ready tab, sudafed and Tylenol but rashes out on right side of face neck and chest with swelling in mouth
More related studies for: Cipro Xr, Pseudoephedrine Hydrochloride
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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Arizona Cardinals
Dockett doesn't want to forget dismal 2010 season
Usually athletes stand in front of their lockers at the start of a new season and focus on the future not on the past.
Not Arizona Cardinals defensive tackle Darnell Dockett. Several times already during training camp he's recounted what he felt during their 5-11 record during the 2010 season.
"Like I said, I'm just excited to go out every day and try to get better," Dockett said. "You know everybody across the league got high expectations. Our expectations are no higher than other people's expectations but it's all about what you do on the field to get better.
"The whole attitude has changed on our team. We're not complaining, guys are staying after. And we just know what 5-11 feels like. At the end of the day, that's a feeling that none of us are trying to experience right now."
All the players ran sprints at the end of training camp every day in Flagstaff and that extra work has continued down in Tempe with the season opener just around the corner.
Dockett has one simple answer for why the defense is going to be better this season.
"Cause we know what 5-11 feels like. You look at the game film from last year and you see how much we didn't play together and how many mistakes we made and things like that�it sucks. But to have the opportunity to go out and redeem yourself again, a lot of games to us is personal."
Dockett's ready for a real game that counts on Sunday against Carolina.
"I'm just excited to play live football. Just being able to be healthy. That's one thing I can say about my team is we got players. Our main focus right now every day we step on the field is to get better. Just remember what 5-11 felt like."
Most Popular
Cardinals Audio
- Jake Plummer, former ASU and Cardinals quarterback - Tuesday November 25Jake Plummer says there's more than just bragging rights riding on this year's Territorial Cup.
- It's Paul's Call with Paul Calvisi! - Tuesday November 25The Territorial Cup is about to get extremely real on Paul's Call.
- Calais Campbell - Cardinals defensive end - Tuesday November 25Arizona Cardinals defensive end Calais Campbell expects the team to bounce back this Sunday against
- Who Impressed/Who Depressed - Monday November 24Dan and Vince discuss who impressed and who depressed them over the weekend.
- Bickley Blast - Monday November 24How vulnerable did the Cardinals look after their loss against the Seahawks?


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Originally published November 11, 2012 at 8:14 PM | Page modified November 11, 2012 at 10:30 PM
Jets left defending their efforts, and their decisions
Rex Ryan asked about his "fatal attraction" to Mark Sanchez
Seattle Times staff reporter
Not that the New York Jets have a quarterback controversy or anything, but coach Rex Ryan was asked after the game Sunday to explain his "fatal attraction" to Mark Sanchez.
No, Glenn Close wasn't in the New York press corps.
That pointed query came after Ryan, in the wake of another ineffectual performance by Sanchez in New York's 28-7 defeat against Seattle, reaffirmed that Sanchez would remain the starter ahead of Tim Tebow.
Despite Sanchez's inability to lead a touchdown drive, compounded by a critical interception in the red zone, Ryan said he still feels the Jets have their best chance to win with Sanchez. When pressed about that belief, he became a bit heated.
"I don't care what you think or anybody else — I believe it," Ryan said. "In my heart, I believe it. I've had, I don't know, how many years coaching football, and I put my trust in him."
The Sanchez/Tebow dynamic is just one cloud — albeit, the most closely observed one — in the world of the Jets, who fell to 3-6. After three consecutive defeats, their playoff hopes are hanging by a thread, as Ryan is well aware.
"It's about a 2 percent chance of making the playoffs, or something like that, with a record that we have," he said. "But we're going to take that shot. (There) is not one quit in any of these guys."
But there also hasn't been one win for the Jets since Oct. 14. And Sanchez's struggles are becoming harder for Ryan to defend. On his way to racking up a quarterback rating of 40.7, Sanchez had two critical turnovers — the interception on third-and-goal from Seattle's 6 (his fourth red-zone turnover of the season), and a fumble in the fourth quarter that led directly to Seattle's final score.
Asked about the team's mood after the interception, guard Brandon Moore replied, "It wasn't a jovial moment."
Moore was equally biting when asked how well the Jets' offense responded to that adversity.
"Well, we didn't score any touchdowns today."
The closest they came was when Tebow, in one of his periodic cameos at quarterback, was poised to score from the 1. That would have put the Jets up 14-7.
"Tebow was going to walk in on that counter play," Ryan said.
Instead, the Jets were called for a false start, and a visibly agitated Tebow exited the field.
"I don't think they were in a good look to stop us on that play," he said. "The frustration was that I knew we let an easy one slip away."
The next play was Richard Sherman's interception of Sanchez's pass — "the start of the turn of things going bad," Sanchez noted.
He added, "We can't win with the way I played today."
Sanchez completed just nine of 22 passes for 124 yards. Tebow, in a somewhat expanded role — seven snaps, plus three plays that resulted in penalties — completed all three of his passes, but for 8 yards. He rushed four times for 14 yards. The sum was not enough to persuade Ryan to make Tebow the lead man.
"I've just got to continue to work hard in my role, and that's it," Tebow said.
Sanchez said he's not thinking about losing his job.
"That never really crosses my mind," he said. "I am too confident for that. We have won too many games together. We've had some great success here, so I don't expect anything different. It's my job to keep playing, play hard, and make better decisions and help this team win."
Sanchez was asked if it's hard to maintain his rhythm in the Jets' quarterback rotation. The reporter noted that in one case, Sanchez threw a 32-yard pass — and before he could complete the question, Sanchez finished the thought: "And came right back out, yeah. It's something we're all getting used to, and I'm getting a better feel for it. We'll keep rolling. When I'm in there, I have to play better and take care of the football."
The upshot was a Jets defeat that Ryan called "brutal." And this being a New York team, the aftermath figures to be the same.
Larry Stone: 206-464-3146 or email@example.com.
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I finally finished my sew together bags! My friend Gina kindly (and calmly) fixed my dress for me last night as I had a bit of a disaster involving an iron and then realising it was possibly too big for me now too. While she did that, I sat and hand stitched the binding down […]
This is me- Kerry- and I live in Leicestershire with my husband, our greyhound Gwen and Pointer puppy Hank. I started out making and selling resin jewellery, but now I am heavily into patchwork. More information is on my about me page!
Long term WIPsHello Chevron Quilt - ten rows of 16 done on the top - 45% complete
Scrappy Log Cabin Quilt - six blocks done, out of 49 (I think) - 10% complete CASUAL PROJECT
Lone Star-esque Scrappy Quilt - needs quilting - 70% complete


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Search results for 'Ahmed Rashid'
Pakistan on the Brink: The Future of Pakistan, Afghanistan and the West
What does the future hold for the world's most unstable region? This title examines the changing casts of characters in this story, the future of the Taliban and international terrorism, and the political manoeuvring both within...
$22.99Buy now
Descent into Chaos: Pakistan, Afghanistan and the Threat to Global Security
Explores the volatile and dangerous region in the world. In this story of squandered opportunities, misguided alliances and double-dealing, the author pinpoints with chilling accuracy where the true threat to our global security...
$28.00Buy now
Pakistan on the Brink: The Future of Pakistan, Afghanistan and the West
Focuses on the long-term problems of Pakistan: the casts of various characters, the international terrorism, and the actual policies and strategies both within Pakistan and Afghanistan and among the Western allies.
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Taliban: The Power of Militant Islam in Afghanistan and Beyond
This is a new, revised edition of the universally acclaimed and best-selling account of the Islamic fundamentalist Taliban movement - the most radical and extreme Islamic movement the world has seen.
$29.95Buy now
Jihad: The Rise of Militant Islam in Central Asia
An exploration of the five Central Asian republics adjacent to Afghanistan - Kazakhstan, Uzbekistan, Turkmenistan, Kyrgyzstan and Tajikistan. Based on research and interviews, it explains the roots of militant rage in Central Asia...
$39.95Buy now
Pakistan on the Brink: The Future of America, Pakistan, and Afghanistan
An urgent, on-the-ground report from Pakistan--from the bestselling author of Descent Into Chaos and Taliban Ahmed Rashid, one of the world's leading experts on the social and political situations in Pakistan and Afghanistan,...
$29.95Buy now
Descent Into Chaos: The U.S. and the Disaster in Pakistan, Afghanistan, and Central Asia
The #1 New York Times -bestselling author provides a shocking analysis of the crisis in Pakistan and the renewed radicalism threatening Afghanistan and the West.
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Jihad: The Rise of Militant Islam in Central Asia
From the author of the New York Times bestseller Taliban comes an in-depth look at an important and overlooked hotbed of Islamic fundamentalism.
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