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ABSTRACT: Introduction Les patients cancéreux ont un risque augmenté d'évènements thromboemboliques veineux. Certaines substances utilisées lors de chimiothérapies ont également été associées au développement de thromboses. Les cas rapportés d'épisodes ischémiques artériels aigus chez des patients cancéreux sont rares. Méthodes Les patients opérés chirurgicalement pour une ischémie aigue associée à une tumeur maligne dans un centre hospitalo-universitaire étaient identifiés sur une période de 10 ans. Les caractéristiques démographiques des patients, les types de cancer, l'utilisation de chimiothérapies, le site de la thrombose, les traitements et les résultats étaient notés. Résultats Quatre cents dix-neuf patients étaient opérés pour une ischémie aigue artérielle. Parmi eux, 16 patients (3,8%) avaient un cancer associé. Les sites les plus fréquents de cancer étaient le tractus urogénital (n = 5) et les poumons (n = 5). Huit patients (50%) avaient été diagnostiqués de leur cancer récemment, et quatre (25%) de ces cancers étaient découverts fortuitement après l'épisode d'ischémie aigue. Quatre patients (25%) développaient une ischémie aigue lors d'une chimiothérapie. L'artère fémorale superficielle était le site le plus fréquent d'occlusion (50%), suivie par les artères brachiales (18%) et poplitées (12%). Tous les patients avaient une thrombo-embolectomie, mais deux (12%) patients nécessitaient un pontage secondaire. Six patients (37%) perdaient leur membre, et la mortalité intra-hospitalière était de 12%. L'histologie révélait que toutes les occlusions étaient dues à une maladie thromboembolique, sans cellule tumorale identifiée. Lors du suivi, 44% de patients étaient vivants à 1 an. Conclusion Le cancer et la chimiothérapie peuvent prédisposer les patients à l'ischémie aigue artérielle. Au contraire d'autres rapports qui retrouvaient que cet évènement était préterminal et mieux traité par des mesures palliatives, dans cette série, un diagnostic et une intervention précoces permettaient un sauvetage de membre et la survie du patient.Annales de Chirurgie Vasculaire. 10/2011; 25(7):1016–1022.
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ABSTRACT: Cancer patients have an increased risk of venous thromboembolic events. Certain chemotherapeutic agents have also been associated with the development of thrombosis. Reported cases of acute arterial ischemic episodes in cancer patients are rare. Patients who underwent surgery for acute limb ischemia associated with malignancy in a university teaching hospital over a 10-year period were identified. Patient demographics, cancer type, chemotherapy use, site of thromboembolism, treatment and outcome were recorded. Four hundred nineteen patients underwent surgical intervention for acute arterial ischemia, 16 of these patients (3.8%) had associated cancer. Commonest cancer sites were the urogenital tract (n = 5) and the lungs (n = 5). Eight patients (50%) had been recently diagnosed with cancer, and four (25%) of these cancers were incidental findings after presentation with acute limb ischemia. Four patients (25%) developed acute ischemia during chemotherapy. The superficial femoral artery was the most frequent site of occlusion (50%), followed by the brachial (18%) and popliteal (12%) arteries. All patients underwent thromboembolectomy, but two (12%) patients subsequently required a bypass procedure. Six patients (37%) had limb loss, and in-patient mortality was 12%. Histology revealed that all occlusions were due to thromboembolism, with no tumor cells identified. At follow-up, 44% of patients were found to be alive after 1 year. Cancer and chemotherapy can predispose patients to acute arterial ischemia. Unlike other reports that view this finding as a preterminal event most appropriately treated by palliative measures, in this series, early diagnosis and surgical intervention enabled limb salvage and patient survival.Annals of Vascular Surgery 08/2011; 25(7):954-60. · 0.99 Impact Factor
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ABSTRACT: Down syndrome, or trisomy 21, has a characteristic constellation of clinical findings, including various congenital heart defects. We report a case of an adult male with Down syndrome who presented with a 3-week history of lower limb pain and swelling, attributed to cellulitis. Clinical and angiographic evaluation identified a below-knee mycotic pseudoaneurysm secondary to infective endocarditis. Surgical aneurysmal repair and revascularization were performed. Various management options are outlined in this report.Vascular 10/2010; 18(5):297-8. · 0.86 Impact Factor
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ABSTRACT: Peripheral arterial disease (PAD) and type 2 diabetes mellitus (DM) are both associated with excessive vascular calcification and elevated levels of inflammatory markers IL-6 and hsCRP. The recently identified Osteoprotegerin(OPG)/RANKL/TRAIL pathway has been implicated in vascular calcification, but data on levels in PAD and effect of co-existent DM are lacking. 4 groups of patients were recruited - 26 with PAD and DM, 35 with DM alone, 22 with PAD alone, and 21 healthy individuals. Serum OPG, RANKL, TRAIL, hsCRP and IL-6 were measured using commercial ELISA assays. Presence and severity of PAD was defined using ankle brachial index (ABI). Serum OPG (7.4±0.3 vs.5.8±0.2 pmol/l, p<0.0001), TRAIL (95.5±5.2 ng/ml vs. 76.2±4.4 ng/ml, p=0.006), hsCRP (2.6±0.3 vs. 1.8±0.3 mg/l, p=0.048), and IL-6 (4.1±0.4 vs. 2.9±0.4 pg/ml, p=0.06) were higher in patients with PAD. There was no difference in RANKL. Only OPG was significantly higher in PAD and DM (7.2±0.3 pmol/l) and PAD alone (7.7±0.4 pmol/l) compared to DM only (5.8±0.3 pmol/l) and healthy controls (5.6±0.4 pmol/l), p<0.01, but OPG was no higher in those with DM plus PAD versus those with PAD alone (p<0.3). Only OPG was associated with PAD severity, correlating negatively with ABI (r=-0.26, p=0.03), independent of age, gender, glycaemic status, hsCRP and IL-6. PAD is associated with higher serum OPG, regardless of the co-existence of DM. This finding, in addition to its correlation with severity of PAD, suggests that OPG may be a novel marker for the presence and severity of PAD, possibly by reflecting the degree of underlying vascular calcification.Thrombosis Research 10/2010; 126(6):e423-7. · 3.13 Impact Factor
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ABSTRACT: The purpose of this study is to evaluate the use of endovascular stent grafts in the treatment of para-anastomotic aneurysms (PAAs) as an alternative to high-risk open surgical repair. We identified all patients with previous open aortic aneurysm repair who underwent infrarenal endovascular aneurysm repair (EVAR) at our institution from June 1998 to April 2007. Patient demographics, previous surgery, and operative complications were recorded. One hundred forty-eight patients underwent EVAR during the study period and 11 patients had previous aortic surgery. Of these 11 redo patients, the mean age was 62 years at initial surgery and 71 years at EVAR. All patients were male. Initial open repair was for rupture in five (45%) patients. The average time between initial and subsequent reintervention was 9 years. All patients were ASA Grade III or IV. Fifty-five percent of the PAAs involved the iliac arteries, 36% the abdominal aorta, and 9% were aortoiliac. Ten patients had endovascular stent-grafts inserted electively, and one patient presented with a contained leak. Aorto-uni-iliac stent-grafts were deployed in seven patients, and bifurcated stent-grafts in four patients. A 100% successful deployment rate was achieved. Perioperative mortality was not seen and one patient needed surgical reintervention to correct an endoleak. Endovascular repair of PAAs is safe and feasible. It is a suitable alternative and has probably now become the treatment of choice in the management of PAAs.CardioVascular and Interventional Radiology 08/2009; 32(6):1165-70. · 2.09 Impact Factor
Article: Concurrent colorectal malignancy and abdominal aortic aneurysm: a multicentre experience and review of the literature.[Show abstract] [Hide abstract]
ABSTRACT: There is lack of consensus regarding concurrent vs. staged approaches, and the prioritisation of staged procedures in cases presenting with colorectal carcinoma (CRC) and abdominal aortic aneurysm (AAA) synchronously. We aim to present our experience, review the literature on this therapeutic dilemma and examine the role of endovascular aortic repair (EVAR). An observational study of the experience of two centres and a systematic review of the published literature. Twenty-four patients were identified from the prospective databases of two tertiary referral centres between 2001 and 2006. Intervention for both malignancy and aneurysm was performed in 13 patients. In 10 patients, cancer resection was performed initially and was followed by open aneurysm repair (n=3) or EVAR (n=7). Two patients (AAA diameters: 7.0 and 8.0cm) underwent EVAR prior to colonic resection. One patient was selected for synchronous surgery. There were no interval AAA ruptures, graft infection or postoperative mortalities. Literature review identified 269 such cases; of these 101 were treated by combined surgery. In staged surgery, there were nine interval aneurysmal ruptures and one aortic graft infection. In our experience, staged management can be undertaken, without interval aneurysmal rupture. EVAR has an evolving role in preventing delay in CRC management, in high-risk patients, and during combined intervention.European journal of vascular and endovascular surgery: the official journal of the European Society for Vascular Surgery 03/2009; 37(5):544-56. · 2.92 Impact Factor
Article: Making the case for cardiovascular screening in Irish males: detection of abdominal aortic aneurysms, and assessment of cardiovascular risk factors.[Show abstract] [Hide abstract]
ABSTRACT: AAA screening programmes have proven to be beneficial and cost effective worldwide for males greater than 65 years of age, with 4.9% males of 65-75 years of age having an un-diagnosed AAA at screening, resulting in a 42% reduction in the risk of rupture in an English population. This study assessed the incidence of AAA and risk factors for atherosclerosis in Irish males of 55-75 years. From April 2006 to December 2007, males between the ages of 55 and 75 years, living within the catchment area of Blanchardstown Hospital were invited for AAA screening using duplex ultrasound and cardiovascular risk factor screening. 1.9% (17/904) of the study population had previously un-diagnosed aneurysms detected, with sizes ranging from 3.0 cm to 5.8 cm (0.6% in 55-65 years old (yo) and 4.2% in 65-75 yo, p<0.01). 33% (302/904) of patients had hyperlipidaemia, while 16% of those with a previous diagnosis of hyperlipidaemia, were inadequately controlled on the test date. 31% of patients had a single elevated blood pressure reading, meriting further investigation for possible hypertension. 3% (28/904) of all patients had a raised glucose levels which had not previously been identified and of those who had a previous history of DM, 46% had abnormal glucose levels. 16% of patients (93/573) were morbidly obese (BMI>30) and 64% (292/573) were overweight. The incidence of AAAs in 65-75-year-old men is similar to international figures. This study confirms that screening for hyperlipidaemia, hypercholesterolaemia, obesity and hypertension may be worthwhile in all males over 55 years, while AAA screening should be reserved for 65-75-year-old Irish males.European journal of vascular and endovascular surgery: the official journal of the European Society for Vascular Surgery 12/2008; 37(3):300-4. · 2.92 Impact Factor
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ABSTRACT: Shortened trainingtimes duetothe European Working Time Directive (EWTD) and increased public scrutiny of surgical competency have led to a move away from the traditional apprenticeship model of training. Virtual reality (VR) simulation is a fascinating innovation allowing surgeons to develop without the need to practice on real patients and it may be a solution to achieve competency within a shortened training period. A Medline search was performed to identify studies and commentaries on the use of VR simulators in endovascular training. Three studies on carotid stenting and four on peripheral vascular angioplasty demonstrate that simulator training is a valid, feasible and acceptable training tool. One randomised study reports that these skills learned on simulators are transferable to the operating room. VR simulators have a role in competency based, structured training of vascular interventionalists and should improve patient safety.The surgeon: journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 09/2008; 6(4):214-20. · 1.97 Impact Factor
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ABSTRACT: We present the case of a 36-year-old female with a three-week history of a pulsatile, tender mass in the anterior triangle of the neck. Radiology demonstrated that this was a vascular tumour deep to the sternocleidomastoid muscle. Pre-operative embolisation and complete surgical resection was performed. Histology revealed Castleman's disease. Unicentric hyaline vascular Castleman's disease is an unusual cause of neck mass. Surgical resection remains the best chance for cure in unicentric disease. Long term follow-up is necessary as the risk of subsequent malignancy exists.Irish Journal of Medical Science 01/2006; 175(1):79-80. · 0.51 Impact Factor
Article: Hydroxymethylglutaryl co-enzyme A reductase inhibition attenuates endotoxin-mediated inflammatory responses.[Show abstract] [Hide abstract]
ABSTRACT: The aim of this study was to investigate whether inhibition of hydroxymethylglutaryl co-enzyme A reductase attenuates leucocyte-endothelial cell interactions and alters expression of endothelial constitutive nitric oxide synthase (ecNOS) and inducible nitric oxide synthase (iNOS) following exposure to endotoxin. Male Sprague-Dawley rats were randomized into control, lipopolysaccharide (LPS) and pravastatin + LPS groups (seven per group). Pravastatin sodium was gavaged at 0.4 mg per kg per day for 5 days, after which LPS 15 mg/kg was administered via the jugular vein. Intravital microscopy was used to determine leucocyte-endothelial cell interactions. Following the administration of LPS there was a significant reduction in leucocyte rolling velocity at 10 min (mean(s.e.m.) 69(3) versus 102(6) per cent of baseline value; P = 0.041), an increase in the number of adherent leucocytes at 10 min (4.5(0.5) versus 2.8(0.3) per 100 microm; P = 0.044) and an increase in the number of leucocytes undergoing transendothelial migration at 30 min (4.2(0.4) versus 1.7(0.4) per field; P = 0.008) compared with controls. Pretreatment with pravastatin significantly attenuated LPS-induced leucocyte-endothelial cell interactions (rolling velocity 89(6) per cent at 10 min, P = 0.038; adherent leucocytes 3.0(0.5) per 100 microm at 10 min, P = 0.038; migrating leucocytes 1.9(0.5) per field at 30 min, P = 0.001). This endothelial protection was associated with maintenance of ecNOS and reduced iNOS expression within mesenteric tissues. These data show that pravastatin produces anti-inflammatory effects in response to injurious stimuli by attenuation of leucocyte-endothelial cell interactions.British Journal of Surgery 09/2005; 92(8):1034-40. · 4.84 Impact Factor
- The surgeon: journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 07/2005; 3(3):160-3. · 1.97 Impact Factor
Article: Hydroxy-methylglutaryl-coenzyme A reductase inhibition improves endothelial dysfunction in type-1 diabetes.[Show abstract] [Hide abstract]
ABSTRACT: We hypothesize that treatment with Pravastatin, a HMG CoA reductase inhibitor would improve flow-mediated dilation (FMD), a nitric oxide dependent phenomenon and the earliest detectable marker of endothelial dysfunction, in asymptomatic patients with type-1 diabetes. FMD of the brachial artery in response to reactive hyperaemia was measured using high-resolution ultrasonography. Young male patients with type-1 diabetes (n=9) were compared with age matched non-diabetic controls (n=8). The FMD response in the control group was a median increase in diameter of 7.9 (range 3.8-12.6)%. In the diabetic group the FMD response was impaired when compared with controls with a median increase only of 4.4 (range 3.7-5.8)% (p<0.01). Following Pravastatin, 40 mg per day for one month in the diabetic group, there was a significant diameter change in response to reactive hyperaemia with a median of 8.4 (range 6.9-12.6)% (p<0.01). These data confirm the presence of endothelial dysfunction in young patients with type-1 diabetes. We have shown that 1-month of Pravastatin treatment normalizes FMD. This suggests that HMG CoA reductase inhibitors may have a role in the management of diabetes mellitus, even in the presence of normal serum cholesterol levels.European Journal of Vascular and Endovascular Surgery 05/2004; 27(4):432-7. · 2.82 Impact Factor
Article: Clinically applicable thermal preconditioning attenuates leukocyte-endothelial interactions.[Show abstract] [Hide abstract]
ABSTRACT: We have previously demonstrated that clinically applicable thermal preconditioning induces heat shock protein 72 (HSP72) and protects against a subsequent ischemia-reperfusion (I/R) injury in an animal model. A core component of I/R injuries is the interaction between activated leukocytes and endothelial cells. We hypothesized that the effects of clinically applicable thermal preconditioning are mediated through attenuation of this leukocyte-endothelial (L-E) interaction. Twenty-one male Sprague Dawley rats were divided into control, I/R, and preconditioning plus I/R groups. Preconditioning was done under general anesthesia and the animals' temperature raised by 1 degrees C for 15 minutes in a water bath. This was repeated once a day for 5 successive days. I/R injury was caused by occlusion of the superior mesenteric artery for 10 minutes followed by 1 hour of reperfusion. L-E interactions were analyzed using intravital microscopy of a mesenteric vessel in vivo. L-E interactions were determined using leukocyte velocity (which decreases as cells interact), and number of adherent and migrated leukocytes. HSP72 was assessed by Western blot. Ischemia-reperfusion caused a decrease in leukocyte rolling velocity at all timepoints (p < 0.05 versus controls). Preconditioning attenuated the effects of I/R, and leukocyte rolling velocity was significantly improved versus I/R (p < 0.05) to levels similar to those in controls. Similarly, the number of adherent and migrating leukocytes increased significantly (p < 0.05) after I/R versus control at all time points, and preconditioning attenuated these to control levels, (p < 0.05 versus I/R) at both the 30- and 60-minute postischemia time points. Upregulation of HSP72 was demonstrated on Western blot. These results demonstrate that the benefit of clinically applicable thermal preconditioning is at least partially because of an immunomodulatory role in attenuating leukocyte-endothelial interactions associated with an increased expression of HSP 72.Journal of the American College of Surgeons 07/2003; 197(1):71-8. · 4.50 Impact Factor
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ABSTRACT: Endothelial dysfunction initiated by monocyte-endothelial interactions has previously been observed in many vasculopathies, including chronic cigarette smoking. Taurine, a semiessential amino acid, and vitamin C, a naturally occurring antioxidant, have previously been shown to have endothelial protective effects when exposed to proinflammatory insults. Therefore, we hypothesized that taurine and vitamin C would restore endothelial function in young smokers by modifying monocyte-endothelial interactions. Endothelial-dependent vasodilatation was assessed in vivo using duplex ultrasonography, and monocyte-endothelial interactions were assessed in vitro using endothelial cell culture (human umbilical vein endothelial cells [HUVECs]) with monocyte-conditioned medium (MCM). Endothelial-dependent vasodilatation was significantly impaired in young smokers compared with nonsmokers. Pretreatment of young smokers for 5 days with 2 g/d vitamin C and, more significantly, with 1.5 g/d taurine attenuated this response. MCM taken from smokers impaired the release of nitric oxide and increased the levels of endothelin-1 release from HUVECs. When HUVECs were cultured with MCM from smokers who had been treated with taurine, the levels of nitric oxide and endothelin-1 returned toward control levels. This was attributed to an upregulation in endothelial nitric oxide synthase expression. These observations suggest that taurine supplementation has a beneficial impact on macrovascular endothelial function, and an investigation of its effect on altered endothelial function in dyslipidemic states is warranted.Circulation 02/2003; 107(3):410-5. · 15.20 Impact Factor
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ABSTRACT: Thermal preconditioning has previously been shown to attenuate ischemia-reperfusion induced injuries, possible due to increased expression of heat shock proteins (HSP). The model of thermal preconditioning used, however, was not clinically relevant as preconditioning was to 41 degrees C, leading to cellular damage. Our aim was thus to establish a novel and clinically applicable method of preconditioning. Twenty-six male Sprague-Dawley rats were split into three groups (nine control, nine ischemia-reperfusion, and eight preconditioned followed by ischemia-reperfusion). To precondition the animals, they were anesthetized and, using a water bath, their core temperature was raised by 1 degrees C for 15 min once a day for five successive days. I/R injury consisted of 30 min of aortic cross-clamping followed by 120 min of reperfusion; control animals had a laparotomy only. Indicators of lung injury were tissue myeloperoxidase, broncho-alveolar lavage protein concentration, and tissue edema. Tissue heat shock protein expression was detected by Western blot analysis. Lower torso ischemia-reperfusion causes significant lung injury versus control, with raised levels of myeloperoxidase 4.53 iu/g to 7.88 iu/g (P < 0.05), raised B.A.L. protein concentration 419 microg/ml to 684 microg/ml (P < 0.05) and altered wet dry ratio 4.63 to 5.50. Clinically relevant thermal preconditioning attenuates all of these parameters back to control levels: myeloperoxidase 3.87 iu/g (P < 0.05 vs I/R), B.A.L. to 284 microg/ml (P < 0.01 vs I/R) and wet dry ratio to 4.44 (P < 0.05 vs I/R). Western blot demonstrated increased expression of H.S.P. 72 in the preconditioned group versus control and I/R alone. Western blot demonstrated increased expression of HSP72 in the preconditioned group vs control and I/R alone. We conclude that clinically applicable thermal preconditioning can attenuate ischemia-reperfusion induced lung injury, possibly through increased expression of HSP72.Journal of Surgical Research 02/2003; 109(1):24-30. · 2.02 Impact Factor
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ABSTRACT: intimal hyperplasia (IH) is a major cause of re-stenosis post-vascular intervention. Induction of heat shock proteins (HSPs), by thermal pre-conditioning, reduces IH. Our aim was to investigate the effect of the pharmacological HSP inducer herbimycin A on IH in the rat carotid balloon injury model. Materials and Methods: thirty male Sprague-Dawley rats were randomized into three groups. All groups underwent balloon injury to the left carotid artery. Stress proteins were induced 18 h pre-operatively by heat shock or herbimycin A. Two weeks post-operatively, animals were sacrificed and carotid intima/media area ratio (I/M ratio) calculated using computerized planimetry. Neo-intimal proliferation was assessed immunohistochemically with PCNA (proliferating cell nuclear antigen). Western blot and immunohistochemistry for arterial HSP70 and HSP27 were performed. heat stress and herbimycin significantly reduced the I/M ratio (p < 0.05 vs balloon injury alone). Neo-intimal proliferation was significantly reduced in the heat stress and herbimycin groups (p < 0.05 vs balloon injury alone). Heat stress induced arterial HSP70 and HSP27. Herbimycin A increased arterial HSP27. herbimycin A significantly attenuates IH after balloon injury. HSP27 may be the HSP involved in mediating this response. Pharmacological inducers of HSPs may have a therapeutic role to play in preventing re-stenosis post-vascular intervention.European Journal of Vascular and Endovascular Surgery 01/2003; 25(1):40-7. · 2.82 Impact Factor
Article: Diethylmaleate, a pro-oxidant, attenuates experimental ischaemia-reperfusion-induced lung injury.[Show abstract] [Hide abstract]
ABSTRACT: Systemic ischaemia-reperfusion (IR) injury is in part an oxidant injury mediated by neutrophils. Diethylmaleate (DEM), an intracellular pro-oxidant agent, has been shown to alleviate neutrophil-mediated tissue injury. The aim of this study was to evaluate whether DEM could have a protective effect on neutrophil-mediated lung injury in an animal model of lower-torso IR. Sprague-Dawley rats (seven per group) were randomized into three groups. The control group underwent midline laparotomy only; the IR group underwent laparotomy and clamping of the infrarenal abdominal aorta for 30 min followed by 2 h of reperfusion; and the third group was pretreated with DEM 6 mmol/kg intraperitoneally 1 h before the IR insult. IR resulted in a significant increase in both microvascular leakage and pulmonary neutrophil infiltration as measured by bronchoalveolar lavage protein concentration and pulmonary myeloperoxidase activity respectively. Pretreatment with DEM significantly attenuated both microvascular leakage and neutrophil infiltration. Preconditioning with DEM protected against IR-induced lung injury. This protective effect raises the possibility of using pro-oxidants to prevent inflammatory injury.British Journal of Surgery 05/2002; 89(4):482-5. · 4.84 Impact Factor
Article: Taurolidine attenuates the hemodynamic and respiratory changes associated with endotoxemia.[Show abstract] [Hide abstract]
ABSTRACT: The purpose of this study was to determine if prereatment with taurolidine, a known anti-endotoxin agent, would attenuate the hemodynamic and respiratory responses associated with endotoxin induced lung injury in a large animal model in a randomized controlled study under license from the Department of Health. All animals underwent a general anesthetic. Vascular catheters were placed in the femoral artery and in the femoral vein. A Swan-Ganz Catheter was inserted for measurement of pulmonary artery pressure. Animals were randomized into three groups: Control, with measurements taken at baseline and half hourly up to 90 min; Endotoxin, receiving 5microg/Kg E. coli endotoxin intravenously after baseline measurements; and Endotoxin + Taurolidine, receiving 5g of taurolidine via intraperitoneal infusion 1 h before endotoxin administration. Main outcome measures were mean systemic arterial pressure (MAP), mean pulmonary arterial pressure (MPAP), arterial oxygen tension (pO2), serum endotoxin concentration, and pulmonary myeloperoxidase. Endotoxin induced a significant lung injury characterized by an increase in pulmonary artery pressure, hypoxia, and systemic hypotension. Pretreatment with intraperitoneal taurolidine significantly attenuated these hemodynamic and respiratory changes. Serum endotoxin concentration was also significantly reduced as was lung myeloperoxidase. The data suggest that taurolidine may have a therapeutic role in preventing the lung injury seen in endotoxemia.Shock 05/2002; 17(4):308-11. · 2.61 Impact Factor
Article: Platelet and endothelial abnormalities that contribute to atherogenesis are early alterations in young male smokers[Show abstract] [Hide abstract]
ABSTRACT: Conclusion The above data demonstrate that the endothelial dysfunction (FMD) previously demonstrated correlates with endothelial injury (vWF) and platelet abnormalities. These are early and possibly synergistic alterations in young smokers that contribute to the development of atherogenesis.Irish Journal of Medical Science 01/2002; 171:19-19. · 0.51 Impact Factor
Article: Endothelial dysfunction and microalbuminuria precede platelet function abnormalities in patients with insulin dependent diabetes[Show abstract] [Hide abstract]
ABSTRACT: Conclusion Using the above parameters, these data demonstrate that this population of type 1 diabetics have no evidence of platelet abnormalities. Further, they indicate that anti-platelet therapy is not required in the early stages of type 1 diabetes and that endothelial dysfunction precedes and is a potential mediator of diabetic platelet dysfunction.Irish Journal of Medical Science 01/2002; 171:45-45. · 0.51 Impact Factor
Top Journals
Beaumont HospitalDublin, Leinster, Ireland
Philadelphia UniversityPhiladelphia, Pennsylvania, United States
The Adelaide and Meath Hospital IrelandDublin, Leinster, Ireland
Connolly Hospital BlanchardstownDublin, Leinster, Ireland
Royal College of Surgeons in Ireland
Dublin, Leinster, Ireland
- • Department of Surgery
- • Department of Anatomy
University of Pennsylvania
Philadelphia, PA, United States
- Department of Surgery
Waterford Regional HospitalWaterford, Munster, Ireland
Hospital of the University of Pennsylvania
Philadelphia, PA, United States
- Department of Surgery


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Dual Flash Light Hot Shoe Adapter Mount Holder Bracket - Black
Color: Black Brand: N A Model: N A Material: Aluminum alloy + iron Quantity: 1Set Type: Monopod Retractable: Yes Max.Load: 5000G
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Bicycle Bike White 5-LED Head Light Torch Flashlight + Red 5-LED Tail Light Set with Mount
. Wearing a reflective vest can help but having lights on your bike is a sure fire guarantee that you will be visible. This set includes a rear light and a headlamp with 3 modes
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Universal Dual-USB + UK Plug Wall Mount Socket - Light Grey
Color: Light Grey Model: 81053u Quantity: 1Piece Material: PC flame resistant plastic + Phosphor Bronze Fireproof Material: Yes Target Country & Region: Universal Rate
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DULISIMAI Convenient Plastic Desktop Mount Holder - White + Light Yellow
Color: White + Light Yellow Brand: DULISIMAI Model: N A Material: Plastic Quantity: 1Piece Mount Type: Desktop Compatible Size: 8cm
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LED Flash Light Cold Shoe + 1/4" Screw Mount Handle Grip - Black
- Material: Plastic
- Color: Black
- Features:
- Great hand-hold bracket for LED lighting or TTL flash light. You are always ready for field shooting and wedding
(1 Review)
» Mounting Accessories
Gun Rail Mount (22mm)
of rail accessory to create a rail interface system. With the gun rail mount, you can attach any type of laser scope, a bayonet, tactical lights, reflex sights and more
More Buying Choices
(26 Reviews)
» Gun Mounts/Rails
Flood-to-Throw Zooming 150lm 3-Mode LED Bike Light w/ Cree P4-WC / Mount (3*AAA)
visible as well as light up those low light areas, with an ultra bright and durable LED bike light, like this one, your concerns can be vanquished. Brand: - Model: - Emitter
(145 Reviews)
5-LED Safety Bike Tail Mount Light 2xAAA
visible as well as light up those low light areas, with an ultra bright and durable LED bike light, like this one, your concerns can be vanquished. Light and Easy Clip design 5
(39 Reviews)
» Bike Light
Wall Mount Automatic IR Motion Sensor Light Switch (AC 180~250V)
than 60W
- Working illumination: 120Lux ± 20%
- Time Delay: 16s ± 20%
- Comes with 2 mounting screws
» Other Electronics
Vehicle Roof Magnet Mount Xenon Warning Strobe Light (Red)
» Car Decoration Lights
Two-Wire System Wall Mount Sound/Light Activated Light Switch (180~240V)
- Voltage: AC 180V-240V
- Load power: =100W for energy saving lamp; =100W for bulb
- Time delay: 50 seconds
- Colour: White
- Lamp wil light by the voice under dark
(3 Reviews)
Studio 1/4" Socket Umbrella Light Flash Mount Stand Holder - Black
mm; Inner Diameter of Umbrella Hole: 9.9mm; Light Hole: 15.8mm; Suitable for most speedlight except Sony & Minolta Packing List 1 x Universal mount holder
(2 Reviews)
Suction Cup Mount Mini Bluetooth v3.0 Speaker - Light Fluorescent Green
Brand N A Model LYV-30 Quantity 1 Color Light fluorescent green Bluetooth Version V3.0 Operating Range 10 meter Compatibility V1.1&V2.0 Microphone Yes Channels 2 Total
» Bluetooth Speakers
4-LED 3-Mode White Light Electronic Bike Horn Warning Light w/ Mount - Black (3 x AAA)
Forward clicky Switch Location Side Lens No Reflector No Flashlight Mounting Tail Beam Range 10m Features With loud volume ring, can be use as bicycle head light, torch, and
5mW 650nm Red Laser Sight w/ Cree LED Flash Light Gun Mount Set (2 x 123A)
turn it into something the special ops would use. This is the JGSD; with a CREE LED light as well as red laser built-in. The laser is a 5mW laser with a 650nm wavelength. It
(9 Reviews)
» Gun Scopes & Sights
Swivel Clamp Holder Mount for Studio Backdrop Camera
- Material: Iron
- Mini-head can rotate 360 degrees
- Can clamp on most light stands, tripods, pipes or board to mount photographic equipments
- The strong clip can be
(10 Reviews)
3-Mode White LED Bike Head Light Torch Flashlight + 7-Mode 5-LED Tail Red Light w/ Mount (5 x AAA)
light uses 3 x AAA batteries not included
- Tail light uses 2 x AAA batteries not included
- Mount bracket with 18mm caliber
40-Pattern LED Bike Spoke Light (Front Wheel Mount)
- Waterproof
- Shuts Off Automatically
- 14 blue LED lights
- Install on the front wheel
- Displays Time Riding & Wheel Rotations
- 40 design patterns and five word
AKSLEN 2-LED 2-Mode White/Yellow Light Bicycle Safety Light w/ Mount Holder (2 x AAA)
flashlight mounting handlebar and helmet Bulit-in Rechargeable Battery N A mAh Power Supply 2 x AAA not included Packing List 1 x Bike light 1 x Mount
Camera Action Mount Holder for Bicycle - Orange
- Color: Orange
- Camera Mount securely attaches your camera or camcorder to handlebars, helmets, and other outdoor gear so you can record all
- Screws directly into
» Bike Holder
- Static power consumption: less than 0.06W
- Loading power: 800W
- Light controlling range: 5Lux~500Lux ± 20% adjustable
- Automatic IR motion sensor switch
- Automatic turn
(6 Reviews)
4-Mode 5-LED Red Light Bicycle Safety Tail Light w/ Bike Mount - Red + Black (2 x AAA)
Type Reverse clicky Switch Location Bezel Lens No Reflector No Flashlight Mounting Tail Beam Range 3m Features 180 degrees rotation light clip, easy to install and
86 Wall Mount Switch Front Panel
- Color: White
- Material: ABS
- Size: 86 x 86mm
- Compatible with 86 wall mount switch back box
- Great for home lighting project
- Comes with 2 screws
» DIY Parts & Components
ZHISHUNJIA ZSJ360-X3 2000lm 4-Mode White 3-LED Bicycle Light w/ Bike Mount - Black (6 x 18650)
Arrangement: Hi , Mid , Low , Fast Strobe Mode Memory: No Switch Type: Forward clicky Lens: Glass Reflector: Aluminum Smooth Flashlight Mounting: Handlebar and Helmet Switch
Flexible Metal 1W 7000K 90LM White 1-LED Wall Mount Light Lamp - Silver (AC 100-240V)
Material: Metal Emitter Type: LED Total Emitters: 1 Power: 1W Color BIN: White Rated Voltage: AC 100~240V, 50 60Hz Luminous Flux: 90LM Color Temperature: 6500~7000K Power
» Table Lights
Mount Holder Clip Clamp for Bicycle Bike LED Light Lamp Flashlight - Black
This Mount Holder Clip Clamp is designed for Bicycle LED Lamp Flashlight. This bike mount for electronic devices is great for all types of riders, from beginners to
2-Mode 5-LED Safety Bike Tail Light with Mount - Red Light (2*AAA)
- Features 5 bright red LED emitters
- 2-mode: Flashing, steady on
- Powered by 2 x AAA batteries not included
Halloween Wall-Mount Scary Skull with Voice Activated Light & Sound (3 x AA)
- Color: White + black + red
- Material: Plastic
- Voice activated Halloween toy, last for about 30 seconds after activated by sound
- Powered by 3 x AA batteries not inc
» Halloweens Costumes
UltraFire 900lm 5-Mode White Light LED Flashlight w/ Strap / Bicycle Mount - Black (1 x 18650)
Color: Black Brand: UltraFire Quantity: 1Set Material: Aluminum alloy Emitter Brand: Cree LED Type: XM-L Emitter BIN: T6 Number of Emitters: 1 Color BIN: White Working Vo
» 18650 Flashlights
LSON Aluminum Alloy Wall Mount Holder for Light Bar (2PCS)
Brand: LSON Model: N A Material: Aluminum Alloy Color: Silver Quantity: 2Piece
» Other Accessories
25mm F1.4 C Mount CCTV Lens w/ Macro Ring / C-M4/3 Mount Adapter - Black
efficient light conductivity
- Package includes:
- 1 x 25mm f 1.4 CCTV Lens
- 1 x C-M4 3 mount adapter
- 1 x Macro ring
(5 Reviews)
» Lenses
Flashlight Universal Bracket Mount Holder with Velcro
Need the light of a flashlight to check a gauge, reset an appliance or perform another important task? With the Flashlight Universal Bracket Mount Holder with Velcro
» Others
5-LED 4-Mode Safety Bike Tail Light with Mount - Green Light (2*AAA)
- Features 5 bright green LED emitters - 4-mode: Strobe On Slow Marquee Scroll Fast Marquee Scroll - Powered by 2 x 1.2V 1.5V AAA batteries sold separately
Universal Mini Flash Hot Shoe Stand for Standard Mount Flash Light - Black
- Color: Black
- Material: Plastic
- Max load: 0.5kg
- Work with all standard hot shoe flash
- Package includes:
- 1 x Stand
2W 150lm 32-LED Red Light Car High Mount Brake Lamp - (12V)
: 32 Power: 2W Wavelength: 635~700nm Actual Lumens: 120~150lumens Rate Voltage: 12V Waterproof Function: No Connector Type: Others Application: Brake light
» Other Car LED Bulbs
Waterproof 3-Mode 3-LED Red Light Bicycle Safety Tail Light w/ Bike Mount (2 x AAA)
- Model: XL-744T
- Color: Red + Black
- ABS case material
- 3-LED red light
- 3 lighting modes: steady on fast strobe take turns flash
- Powered by 2 x AAA batteries not
(7 Reviews)
1/4" 3/8" 5/8" Spigot Adapter Screw for Camera / Flash Trigger / Mount / Light Stand / Tripod
- Color: Silver - All-aluminum alloy material, electroplated surface, anti-wear, anti-oxidation, durable - Multi-combination design, can be used for devices with 1 4" or
(8 Reviews)
DUALANE Quick-Flip Flash Bracket Mount Light Shoe Holder for DSLR Camera / Speedlight - Black
bottom of your camera using a standard sized screw mount;
Can adjust the angle of the camera and the flash independently;
Made of heavy duty aluminum;
Professional black
This band is designed for bike l Bicycle,LED lamp, Flashlight etc. Made of high quality materials, lightweight,but it fits the devices well. Easy-mount and easy-release
UltraFire UF-762 220-Lumen White Light Flashlight w/ Gun Mount (1 x 18650 / 2 x 16340)
27~50cm Others Features: Gun mount caliber 2~2.5cm
DUALANE Swivel Triple Hot Shoe Mount Adapter Flash Umbrella Holder Bracket Light Stand - Black
Color: Black Brand: DUALANE Model: C00789 Material: Aluminum Alloy Quantity: 1Piece Type: Monopod Retractable: No Max.Load: 1000G
New Floral Crystal Flush Mount with 20 Lightings
- Material: Metal, Glass, Crystal
- Suitable Places: Living room, Dining Room
- Coverage square : 15-40m2
- Input Voltage V : 220
- Power W G4X20 20W
- Dimension Inch : L
» Ceiling Light
Creative Butterfly Shaped 360 Degree Rotary Mount Holder for IPHONE / IPAD - Light Green
Color: Light Green Quantity: 1Piece Material: Steel + PU leather Shade Of Color: Green Compatible Models: IPHONE 5S , IPAD MINI 1ST GENERATION , IPAD 4 , THE NEW IPAD
Super Fire 14V Wf501D CR123A With Gun Mount
bright 14V Xenon light cutting through rain and fog
Remote pressure pad for easy on off operation
Gun mount included, see dimension here
Weather seal and durable construction
(12 Reviews)
» HID Xenon Flashlights
11" Magic Arm with Hot Shoe Mount & Camera Mount for DSLR Camera - Black
- Color: Black
- Material: Aluminum alloy
- Great for mounting monitor onto DSLR Camera
- One side connecting to monitor, LED light or other accessories
- Another side
Vent Mount for 3.5'' Garmin Nuvi 1255 + 1355 + 1200 + 1250 - Black
he vent mount is light weight, easy to install and remove, it has a garmin standard 17mm diameter ball-head, compatible with all nuvi cradles. With this gear, you will
» GPS Holders
Side Mirror Mount 9-LED 0.58W Turning Signal Yellow Lights for Cars (12V DC)
T Type Bicycle Bike Handlebar Extension Mount
- Material: plastic
- Use this extension for lights, GPS and phones etc.
- Fits most handlebars
- Comes with installation accessories
(11 Reviews)
86 Wall Mount Switch Back Box - White (7cm-Depth)
- Color: White
- Material: PVC
- 86 model wall mount switch back box
- Depth: 7cm
- High flame retardant performance
- Great for home lighting project
360 Degrees Rotation Mount Holder Clip Clamp for Bicycle Bike LED Light Lamp Flashlight
- Model: RS2966
- Material: ABS + silicone
- Easy to install and remove
- Suitable for flashlight: diameter 20~45mmmm
- 360 degrees rotation
- Hold the flashlight on your
180 Degree Rotateable 3 Section Flash Light Mount Stand Holder - Black + Grey White
Color: Black + Grey White Material: Aluminium alloy Quantity: 1Piece Retractable: Yes Fold Dimensions: 180 Screw Size: 1 4 3 8 Min.Height: 5cm Max.Height: 16cm Max.Load:
3-Mode 12-LED RGB Bicycle Safety Tail Light w/ Bike Mount (3 x AAA)
- Plastic case material
- 12-LED green red blue lights each color with 4-LED lights
- 3 lighting modes: steady on all lights flickering changes color in turn
- Powered
Professional Laser Sight Rifle Scope with Gun Mount (3.5-10x40)
maximizes light transmission for superior brightness and clarity
- 40mm objective diameter
- 3.5x-10x magnification
- 5mW Red laser sight
- Illuminated red and green Mil-Dot
Bicycle 8-Sound Electric Horn + 5-LED Neutral White Caution Light w/ Bike Mount (2 x AA)
- Number of Modes: 8
- Switch Type: Button
- Switch Location: Slide switch
- Flashlight Mounting: Handlebar
- Beam Range: 10~15 meters
- Features: Size: 9.4cm length x
Bike Bicycle 1-Mode 1-LED White Head Light with Strap & Mount Bracket (3 x AAA)
- Model: SF-231
- Color: Black
- Material: ABS + aluminum
- Voltage: 4.5V
- Powered by 3 x 1.5V AAA batteries not included
- Comes with strap & mount bracket
Flower Shaped 7-Mode 7-LED Red Light Bike Laser Tail Lamp w/ Mount Holder - Red + Black (2 x AAA)
Brand N A Quantity 1 Color Black + red Material PC Color BIN Red Number of Emitters 7 Voltage Input 1.5 V Battery Configuration 2 x AAA included Runtime 9h Number of Mode
Wall Mount Automatic IR Motion Sensor Light Switch (AC 180~250V / Three-Wire System)
- Model: XD-305
- Color: White
- Fire retardant PVC material
- Automatic IR motion sensor switch
- Automatic turn on off while detected people come or left
- Detecting Ra
Three-Wire System Wall Mount Automatic IR Motion Sensor Light Switch (100~250V)
Illumination: 5Lux
- Time Delay: 60 + - 20s
- Lode type: Energy-saving light, light tube, LED lights, incandescent light, exhaust fan and more
- Automatically on while people come
Wire System Wall Mount PIR Motion Sensor Switch (180~240V)
- Automatic Sensor Switch is based on infrared technology, automation products - People come, lamp lighting. People left, lamp shutdown - Cordial and friendly, save
BD8792 20mm Rail Scout Light Mount w/ QD Sling Swivel for M4 / R15 / M16 / AK47 - Black
Color: Black Model: BD8792 Material: Aluminum alloy Quantity: 1Piece Gun Type: M4 R15 M16 AK47 Rail Size: 20mm Mount Type: Weaver Ring Diameter: 0
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Felix Sturm vs. Sam Soliman Live stream : Watch Sturm vs Soliman Sturm Fight online 1st February 2013 . Sturm vs Soliman live Stream . Watch Felix Sturm vs Sam Soliman live Boxing Streaming February 1, 2013 from ISS Dome, Düsseldorf, Nordrhein-Westfalen, Germany (Main Event / SAT1) . Felix Sturm vs. Sam Soliman Live streaming,tv schedule,watch Felix Sturm vs. Sam Soliman Live streaming,Sturm vs. Soliman live,Felix Sturm vs. Sam Soliman Live sstreaming,tv schedule,watch Felix Sturm vs. Sam Soliman Live streaming,Sturm vs. Soliman live boxing,video,tv channels,live video,tv channels,live
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By Allan Fox: 33-year-old former WBA middleweight champion Felix Sturm (37-3-2, 16 KO's) has a crucial fight on his hands against #1 IBF Sam Soliman (42-11, 17 KO's) in an IBF middleweight eliminator bout at the ISS Dome in Dusseldorf, Germany. Sturm needs this fight so that he can get a second crack against IBF middleweight champion Daniel Geale after having been beaten by Geale last year in September in an upset loss in Germany. Sturm, who had previously had the judge's side with him in a number of controversial fights, found himself finally on the other end of a decision in getting beat by Geale.


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A Kitchener firefighter takes a close look at the damage after a car...
Walter Hachborn, co-founder of Home Hardware Stores Ltd., is being...
— It hasn't taken Orlondo Steinauer long to get noticed in the CFL.
Melissa Rivers is to honour her late mother, Joan Rivers, tonight...
People's hearts are a little bigger than average here in Waterloo Region.
Participate in the Record's Getting To Know You Contest! Fill out this...
Plenty of us have a perfectly understandable fear of frying. After all, it...
CAMBRIDGE — Pete MacAulay remembers the first time he saw iconic Canadian punk band Teenage Head on stage.
It happened at the Coronet hotel in Kitchener in 1979 with MacAulay — then 22 and a wannabe rock star — rocking along in awe.
"That was the sound I had in my head. They beat me to it," says the owner of MacAulay Music on King Street.
Now — at 55 and a grandfather — he's the resilient band's new lead singer.
"I've been a fan of the band since day 1," he said. "They were the major inspiration to get me playing."
MacAulay went on to sing and play guitar in bands around hometown Cambridge. Along the way, he got to know the members of Teenage Head down the road in Hamilton, including frenetic frontman Frankie Venom.
"He was like a combination of Beetlejuice and Elvis Presley. He was fun, sexy and dangerous."
MacAulay never planned to take Venom's place after he died of cancer in 2008.
Fate had other ideas. MacAulay dropped by memorial jam sessions in Hamilton, where Teenage Head fans and bands gathered to share and perform such Teenage Head classics as Picture My Face or Take It.
By the middle of 2010, MacAuley was asked to take the mike at some shows.
Steve Mahon played guitar at the band's first show in 1975 and has never missed a show since. In March, he told the Hamilton Spectator that MacAulay is a comfortable fit with the band.
"To do this properly you need a guy who doesn't have a predetermined image, and that's exactly who Pete is," Mahon said.
"He treats the vocals just like another instrument, which is what it is. It's rock 'n' roll."
MacAulay called his new musical job "just incredible fun. It's the most fun I've ever done ...
"I'm taking Frankies' space, not his place. It's not a tribute. We've mourned him. We're moving on."
Local baby boomers haven't forgotten Teenage Head, MacAulay said. They come up at shows and talk about songs they remember from a moment at a wedding or a party.
"It's been the sound track of people's lives," MacAulay said.
People call Teenage Head a punk band, but it's nothing like the genre's angry foundations in troubled 1970s Britain. North America's punk bands were more about energy and putting on a show, MacAulay said.
"People say Teenage Head were Canada's Ramones. Well, I say The Ramones were America's Teenage Head."
That's why Teenage Head is still around and attracting a younger generation to live shows, he said.
"It's a huge party fun-time band ... I'm the keeper of the flame."
Fall gigs are lining up across the Toronto area, Hamilton, Brantford and Cambridge at the 515 music bar on Queen Street.
There was a time when MacAulay dreamed of being a rock star and selling albums by the thousands. Those times are history, with the internet allowing anyone to copy recordings with a click of a mouse.
"There's no payday anymore for bands," MacAulay said.
So it's back to basics: rocking the house at bars and house parties, fall fairs and weddings.
"We'll see where it goes. We're having fun with it," MacAulay says.
You've packed, bid farewell to neighbours and arranged for your change of address through the post...
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Drewlo Holdings Inc. offers some of the nicest and most well-appointed apartments for rent across...
Valet Car Wash in Guelph, Ontario is where you can find a exceptional car cleaning experience....


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Podcasts! State Of The Game With Lloyd Cole; Scottish Golf
Podcasting is making a comeback (if it ever went away) thanks to the breakout murder mystery Serial, highlighted by David Carr in this week's New York Times media column on the continued strength of podcasting.
This is a convenient setup for not one, but two podcasts to consider for your Thanksgiving travel plans.
I recently sat in for episode 42 of the Scottish Golf Podcast with Ruairidh Macdonald to chat about Scotland golf travel. If you are planning a trip or thinking about one, check out the many fine episodes covering an array of important topics here and follow the show and/or Ru on Twitter. You can also subscribe via iTunes or via your preferred podcast app (my new favorite IOS app: Overcast.)
Meanwhile, after using his music to open State of The Game for 49 episodes, we finally got Lloyd Cole to appear while on break from touring and hickory golf. Cole recently released Standards in the United States where it was recorded and which has been the focus of his international touring over the last year.
Reviews of Standards have been oustanding, including The Independent suggesting it is Cole's best work, the Mail saying it's "a vibrant set full of wry wordplay," and 4-star reviews from the The Mail, Big Issue and The Independent. (His record label's purchase page including vinyl option, iTunes $9.99 download, Amazon CD $12.99 purchase. I highly recommend!)
As usual, Rod Morri, Mike Clayton and yours truly covered an array of topics, including how Lloyd got started in the game, his love of hickories and Hogan, the state of the game and how his affection for the sport is viewed by his music fans.
You can download the show as an MP3 here, listen to the show directly here, grab it on iTunes here or listen below. There is also this directory of past shows. Happy Thanksgiving!


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Jay, New York
|Jay, New York
Jay Bridge, Jay, NY
|Coordinates: 44°23′8″N 73°42′38″W / 44.38556°N 73.71056°W
|United States
|New York
|• Type
|Town Council
|• Town Supervisor
|Randall T. Douglas (D)
|• Town Council
Members' List
|• Total
|68.3 sq mi (176.8 km2)
|• Land
|67.7 sq mi (175.4 km2)
|• Water
|0.5 sq mi (1.4 km2)
|837 ft (255 m)
|Population (2010)
|• Total
|Time zone
|Eastern (EST) (UTC-5)
|• Summer (DST)
|ZIP code
|Area code(s)
|FIPS code
|GNIS feature ID
Jay is a town in Essex County, New York, United States. The population was 2,506 at the 2010 census. The town is named after John Jay,[1] governor of New York when the town was formed.
The Town of Jay in on the north border of the county and is 25 miles (40 km) southwest of Plattsburgh, 25 miles (40 km) west-southwest of Burlington, VT, 79 miles (127 km) south of Montreal, Quebec, and 118 miles (190 km) north of Albany, NY.[2] Jay is inside the Adirondack Park.
Lower Jay, New York and Upper Jay, New York were originally known as "Mallory's Bush", after the principal settlement, based on early settler Nathaniel Mallory, who arrived around 1797 from what is now called Mallorytown Landing in Front of Yonge, Ontario, While Au Sable Forks was always known as just that.
The Township of Jay had its named changed in honor of New York State Governor John Jay and it was formed in January of 1798 from part of the Town of Willsboro. Afterwards, part of Jay was used to form, in whole or part, the Towns of Keene (1808), Elizabethtown and Wilmington (1821). In 1822, the town was increased by territory from the Town of Chateaugay (now in Franklin County), and the Town of Peru (now in Clinton County).
Lumber production and iron ore extraction were important to the early economy of the Township.
Land of Makebelieve, a former theme park (1954–1979), was located in Upper Jay.
According to the United States Census Bureau, the town has a total area of 68.3 square miles (177 km2), of which, 67.7 square miles (175 km2) of it is land and 0.5 square miles (1.3 km2) of it (0.76%) is water.
The north town line, partly defined by the Ausable River is the border of Clinton County. The East Branch of the Ausable River flows northward near the west town line.
New York State Route 9N is a north-south highway through the town, following the course of the Ausable River.
As of the census[3] of 2000, there were 2,306 people, 918 households, and 651 families residing in the town. The population density was 34.0 people per square mile (13.1/km²). There were 1,443 housing units at an average density of 21.3 per square mile (8.2/km²). The racial makeup of the town was 98.44% White, 0.30% African American, 0.22% Native American, 0.13% Asian, 0.17% Pacific Islander, 0.26% from other races, and 0.48% from two or more races. Hispanic or Latino of any race were 0.61% of the population.
There were 918 households out of which 30.2% had children under the age of 18 living with them, 58.0% were married couples living together, 8.1% had a female householder with no husband present, and 29.0% were non-families. 23.6% of all households were made up of individuals and 11.3% had someone living alone who was 65 years of age or older. The average household size was 2.50 and the average family size was 2.92.
In the town the population was spread out with 24.1% under the age of 18, 6.2% from 18 to 24, 28.2% from 25 to 44, 26.1% from 45 to 64, and 15.4% who were 65 years of age or older. The median age was 40 years. For every 100 females there were 93.9 males. For every 100 females age 18 and over, there were 97.3 males.
The median income for a household in the town was $35,612, and the median income for a family was $39,954. Males had a median income of $29,145 versus $21,438 for females. The per capita income for the town was $16,673. About 6.9% of families and 8.7% of the population were below the poverty line, including 7.8% of those under age 18 and 11.7% of those age 65 or over.
Communities and locations within the Township of Jay[edit]
* Au Sable Forks – Au Sable is two, individual French words which translate into Au for Of and Sable for Sand ... it is pronounced Au Saw'ble. Au Sable should never be clustered! It reads in English as Of Sand Forks, or Au Sable Forks. *The Township of Jay Town Govt. Offices ~ *Community Center, and *Museum are located within Au Sable Forks, New York.' *Emergency Services: The Au Sable Forks Fire Department, The Au Sable Forks Ambulance Station; Doctor's Office and Dental Office; *The Schools: Au Sable Forks Primary School, and Holy Name Catholic School Grades k ~ 6; (2), *Three Churches, Holy Name Catholic, United Methodist and the Episcopal Church are all located along Main Street; *Businesses and Services include, Medos A. Nelson American Legion ~ Post 504; The Bank; Tops Grocery Store; Hollywood Theatre; Au Sable Forks Free Library; Au Sable Forks Gulf Course; The Riverside Bowling Lanes; Tahawus Lodge Center of the Arts; *Eateries and Shopping.
- Au Sable Forks is where the East Branch merge with the West Branch of the Au Sable River at " The Forks " in the center of Town is where the Au Sable River becomes one confluenece. Former homes of James and John Rogers of the J&J Rogers Company are located there ~ The J & J Rogers Iron Ore Mining and Forges, Au Sable Nail Factory, Rolling Mill Forge, Charcoal Kilns, and Lumber Industries, the J & J Rogers Co. Pulp and Paper Mills were located. The J & J Pulp Mill Dam which had generated enough power for this Industrial Village, the J & J Rogers Company homes and some surrounding areas. This hamlet, Au Sable Forks spreads into two different counties, which is divided by the West Branch and Main Branch of the Au Sable River. One Part of Au Sable Forks is within Clinton County to the North across the Main Street Bridge within the Township of Black Brook while the other being the Township of Jay within Essex County is to the South of the Main Street Bridge. ~
- Rome Section – A small residential area is west of Au Sable Forks on the West Branch of the Au Sable River*. The J & J Rogers Co. Pulp Mill, and Dam were located at the end of this road.
- The Grove – Small, close knitted community of residential homes were located along the Main confluence of the Au Sable River, a half mile from town. It was just below "The Forks" were both the East and West Branches of the Au Sable River merge. This area had suffered repitative floods and, or ice jams since 1856. It was the first hamlet within the Township of Jay to successfully secure a FEMA Buy Out in 1997 due to the massive devastation from the 9th of November 1996 flood, and the sheer determination of the residents there.
- Jersey Section – This small residential community is located across the Jersey Bridge at the end of Main Street.
- Green Street – is on the outshirt of "The Forks" Southeast of Au Sable Forks.
- North Jay – A hamlet on the outskirt of Au Sable Forks Village, located on County Road 64, today, known as Stickney Bridge Road but was always known as the North Jay Road for the obvious reason. It not part of the Jay hamlet!
- Au Sable Acres – Known today, as "Forever Wild" is small community located near the banks of the West Branch Au Sable River, comprising several hundred year-round inhabitants and seasonal residents. It is partly within Au Sable Forks and Jay, New York.
- Jay – (formerly "Mallory's Bush") – The hamlet of Jay was originally Lower Jay. It is in on NYS ~ Rt.9N by the East Branch of the Au Sable River. It is considered the oldest settlement in the Township. It is well known for its 1857 Covered Bridge which was located below the village Green near the Rapids, a very popular swimming hole. The Covered Bridge was deemed unsafe by NYS DOT which was closed, then removed. The new Covered Bridge has many original hand hewed beams in the interior of the new construction which was officially opened as a foot bridge in October 2007.
- Upper Jay – (formerly Mallory's Bush) – A hamlet southwest corner of the Townhip of Jay on NYS ~ RT.9N and the East Branch of the Au Sable River. This is were one of the oldest Amusement Parks in our country was created .... The Land Of Makelelieve by Arto Monaco. It was lost due to repetative flooding and, or ice jams along the East Branch of the Au Sable River.
- Historical Facts by– Sharron Hewston, Township of Jay Township of Black Brook Historian.
Notable residents and natives[edit]
- Isaac Finch (October 13, 1783 – June 23, 1845), a U.S. Representative from New York.
- ^ Gannett, Henry (1905). The Origin of Certain Place Names in the United States. Govt. Print. Off. p. 168.
- ^ Wolfram Alpha, nearby cities Jay, NY Accessed: 4/25/2012
- ^ "American FactFinder". United States Census Bureau. Retrieved 2008-01-31.
External links[edit]
Coordinates: 44°22′30″N 73°43′42″W / 44.37500°N 73.72833°W


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A stroll down dismember-y lane...
The violent blood-em up to start them all is reborn in 3D.
A stroll down dismember-y lane...
Censors step in to spoil the gore-fest
Crunchy visceral horror in this new Splatterhouse gallery
A fresh look at the 2D survival horror from Namco Bandai
Bloody rip-'em-up gets appropriate release date
Bloody violence set to heavy, heavy metal
Going out on a limb - then lopping it off...
Blood, gore... and opera?
Fear of entrails? Look away now
Retro remake out in Europe next year


text: Publications Search Results Users may wish to consult What's Included in the Bibliography. Results 1 - 1 Results per page: 25 50 100 Sort by: Pub Date (newest) Title Recent Additions Author Clear All Pub. Year Citation 2002 Wetherell, Julie Loebach, Pedersen, Nancy L. Anxiety, cognitive performance, and cognitive decline in normal aging. Journals of Gerontology, Series B: Psychological Sciences and Social Sciences. 57B, (3), P246-P255. Full Text Options: DOI Worldcat Google Scholar Export Options: RIS EndNote XML [1]


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Did You Know...
-Lourdes was founded in 1958 and known as Lourdes Junior College until 1973 when the title dropped 'Junior' and was known as Lourdes College until 2011 when it transitioned to Lourdes University.
-Lourdes for Life is an initiative established to encourage students to develop a lifelong relationship with Lourdes by educating the student body about Lourdes' history and tradition and the benefits of remaining connected to the institution beyond graduation.
-There are 12 Men's and Women's sports teams and competitive Cheer and Dance on campus.
-2,621 students enrolled in classes for the 2013-2014 school year.
-Sister Gretchen makes 80 pies, 350 dozen cookies, 100 loaves of coffee cake, 210 fruitcakes, 700 dipped marshmellows and much more for her annual Holiday Bakesale.
-This year 30 students, faculty and staff have joined Habitat for Humanity and will be travelling to Maryville, TN and Prattvill, AL.
-The Sisters of St. Francis is a community of nearly 200 Sisters, ministering in 12 states – Indiana, Kentucky, Louisiana, Michigan, Minnesota, Mississippi, New Mexico, North Carolina, Ohio, Texas, Virginia, West Virginia – and Haiti.
More than 300 people attended the 5th annual Franciscan Village Day celebration on October 2, 2014 in the Franciscan Center. In honor of St. Francis of Assisi, whose feast day is October 4 and is known for his care for the earth, the Village threw a "zero waste" lunch, talked about the importance of "Sister Water". The goal of the lunch was to feed 400 and produce no waste for a landfill. The lunch generated less than one pound of scrap that went into traditional garbage. Read more...
This year the Sisters invited those who had made the pilgrimage to Assisi as well as their Associates to participate in their Chapter of Mats, a gathering of all the Sisters for renewal and reconnecting. The days were spent learning more about St. Clare, imbibing the spirit of St. Francis and feeling connected to the Sisters and their mission. It was a "village" gathering as a unique power point presentation highlighted all those who share in the ministries of the Sisters.


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La Cresta Inn is located in Via España wich is a main artery on the Panama city having nearby all banking, insurance or any other business buildings. Hotel have a shuttle to go shopping, to the airport and many other interesting places to visit. Hotel is placed in a small building with only 6 plants. It does have a pool... More
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Yesterday, at the American Copy Editors Society's annual conference, AP Stylebook's David Minhorn and Darrell Christian revealed some of the latest changes in AP style. Although they said they didn't have any bombs to drop, one went off anyway.
Over is now "acceptable in all uses to indicate greater numerical value." More than can still be used to mean the same, but that didn't stop some attendees from tweeting items like:
@violindan: Over a few people are upset.
Announcements about new ways to widely distribute creative works simultaneously thrill us and worry us. Those who work with writers and other artists tend to favor access to information and the broad exposure such moves create. But we worry about the further surrender of individual control.
This is true for written works, but the focus in the past week was on the library of photographs owned by Getty Images. Getty announced its images could be shared and used on noncommercial websites.
National Grammar Day is hard to contain in just one day or within the borders of one nation. Of course, every day is grammar day to a copyeditor
National Grammar Day is March 4, easy to remember because it can be said as "march forth," which is a sentence in itself with imperative verb and implied subject. Of course, "march fourth" also is a sentence, theoretically useful for establishing the order of bands in a parade.
There is something safe about the simple form of haiku. Structure can give the poet freedom, a simple structure especially so. Free verse forces the writer to create the rhythm as well as the words. Haiku forces us into a familiar pattern, one that is fairly easy to exploit.
The assassin's shot that sparked "the war to end all wars" was fired 100 years ago in June, and four years of fighting gave rise, as wars tend to do, to many words that have stuck with us: shell shock, cushy, tank, trench coat, ack-ack, and more.
Linguist and Columbia University professor John McWhorter has been causing a ruckus lately with his comment in a Slate article that you could remove commas from
a great deal of modern American texts and you would probably suffer so little loss of clarity that there could even be a case made for not using commas at all.
a great deal of modern American texts and you would probably suffer so little loss of clarity that there could even be a case made for not using commas at all.
It didn't exactly go viral, but BuzzFeed's new style guide has generated a lot of chatter.
Featured Topic: Editorial Methods
This week's News Roundup includes replacing worn-out holiday words, clarifying a confusables pair, and writing SEO-friendly headlines.
Oxford University Press has quietly rolled out a resource copyeditors have been wanting for years at a price that suits self-funded budgets: an easily searchable online edition of Garner's Modern American Usage.
Garner's is the most thoughtful, comprehensive, and up-to-date reference for what careful writers deem correct English usage. It's an invaluable guide for copyeditors.
Earlier this week, the American Copy Editors Society hosted a Twitter chat about its upcoming annual conference. In addition to reinforcing why you should attend (training, networking), there were tips on how to make the most of your conference.
See all upcoming courses»
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"All things bright and beautiful,
all creatures great and small,
all things wise and wonderful:
the Lord God made them all."
-Cecil Frances Alexander
from All Things Bright and Beautiful
Cats are interesting creatures. I love their individual personalities and the "I will, but only because I want to," mentality they project. There's something comforting about a cat curling up on my lap in the evenings.
So when our friend Gail's neighbor knocked on her door with a puppy in her arms and said, "My mother won't let me keep her, but Gail said you might be willing to take her," my first reaction was, "Are you kidding? No thank you!" Then I glared at Gail, who had quite obviously set us up for this "unexpected" visit.
I've had dogs before. And I've loved them. But it's been a year since our cocker spaniel Lightning was hit by a car and killed, and, while I've missed him, I'll admit I've not missed the responsibilities that come with owning a dog.
While I was saying my peace, however, little did I know my husband was falling in love behind my back. When I turned around, there was this adorable black and white puppy with the most soulful eyes cuddled against my husband's chest.
And then she licked his cheek.
>Instead of immediately echoing my "No thank you," Bill wiped off his cheek and said, "Well, aren't you a cutie." We learned she was a 5-week-old border collie and Labrador mix called a "Borador." And since no one wanted her she was going to have to be taken to the animal shelter, where she would likely be euthanized.
Just the thought of that sweet baby being taken away caused Bill's arms to tighten around her. "What do you think?" he asked. "Would the kids like her?"
We agreed we'd at least talk about it over dinner. Later, as we sat across the table from Gail, talk about "the puppy" soon turned to a discussion of "Maggie." A phone call to our eldest son brought the response that got me: "Well, Momma, nothing could ever replace Lightning, but I think we could find room for her."
So, after a promise to me that he would get up with her and have the major responsibility for her care, Bill suggested we take her home.
Then he threw in the kicker: "If you let me ... umm, us ... keep her, you can take back all my Christmas presents. This is all I need."
So instead of a trip to the mall to finish our Christmas shopping, our Saturday evening turned into a search for puppy supplies.
And now it's back to house training and vet bills once again. Darned if she isn't the cutest puppy I've ever seen.
Yeah, she licked my cheek, too.
"God gave us eyes to see them,
and lips that we might tell
how great is God Almighty,
who has made all things well."
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Australia: Day 1
I know that my blog has been neglected over the last few years, but what better time to attempt to give it new life than when I've travelled to the other sid of the planet?
I left Amsterdam on Tuesday at 2200h, and arrived here in Sydney roughly 24hours later, or Thursday morning at 0600h for those not yet fully understanding the pain of travelling east through ten timezones. We had a 3 hour stopover in Dubai, which was a little exciting until I realised that the airport is effectively a giant mall that also has planes. They did have a McDonald's though, with the signage in Arabic, and a menu which contained no pork ;-)
The architecture of the airport is pretty amazing though: Insanely high ceilings, with walls of steel and glass. I couldn't get a view of the giant tower in the downtown core though -- not from the ground at least. From the air, Dubai is about as depressing as you'd expect: hectares and hectares of tiny clay buildings, and then off in the distance beautiful spires reaching into the sky. Not that income equality isn't a problem in North America, but Dubai is definitely below the curve on this issue.
I actually managed to get some sleep on the 13hour leg from DXB to SYD and then in a jetlaggy stupor proceeded to spend about three hours in Sydney's congested airport eeking through customs with two over massive flights and three agents processing us. I picked up a SIM card at the airport too (why doens't every airport make it this easy?): $20 for 1GB/day and infinite local calls / texts.
I got into the hotel Steph had booked for us (she'd already been here for a day and was at the conference when I checked in), walked down the hall and entered the room, at which point all of the blood left my face as I yelled HOLY SHIT and ran to the other side of the room. Our room had an unwanted guest, a spider roughly the size of my fist and it was hanging out by the front door. I considered trying to get the hell out of there, but it was guarding the door now, so I called reception for help. A maintenance guy showed up with a broom and attempted to remove the beast -- note that I didn't say "kill it with violence", but rather "remove" it, as apparently there are rules about killing GIANT FUCKING ARACHNIDS here. With much skill, he wrestled with the thing for a few minutes (it was a jumper, jesus christ), and he managed to coax it into a drinking glass and then take it outside.
I did some digging on the internetz to figure out what it was that clearly wanted to devour me in my hotel room, and it turns out that it was probably a crab spider. Its bite is venomous (and probably hurts and awful lot) but is non-lethal to humans. This doesn't make it any less scary though, and its brethren are all skittering about... just outside this hotel room. Honestly, I don't understand why anyone would want to visit a place that has beasts like this -- let alone live here.
For those interested, here's a picture of the creature in question, taken with my phone, from the far side of the room as I awaited rescue. Note the door hinge in the foreground for scale. The internetz tell me that these things grow to about 7cm in diameter, which sounds about right.
Once I was well showered, I headed over to the conference where I learnt some really cool stuff about how GitHub captures and logs front-end errors, as well as some pretty cool stuff about how we evaluate languages and frameworks.
...and now it's 0730 and we've got to get ready to head out to the conference again. But first, Stephanie has promised me that there's a good breakfast place nearby. I just have to keep an eye out for dragon bugs on our way there.


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Originally written on isportsweb.com | Last updated 11/15/14
The Baltimore Orioles acquired Scott Feldman from the Chicago Cubs on July 2, since Aug. 3 Feldman has been one of the O's best starting pitchers. (Photo credit: Greg Fiume/Getty Images) The Baltimore Orioles have not been playing particularly well lately — they're 4-6 in their last 10 games and have lost three straight to the New York Yankees. The Orioles are currently on the outside looking in when it comes to the postseason, virtually eliminated from the American League East race as they trail the Boston Red Sox by 11 games with 17 left in the regular season. If the Orioles are to make the postseason it would likely be as one of the AL Wild Card teams, they trail the Tampa Bay Rays by 2.5 games for the second Wild Card spot. Back in early July, the O's acquired Scott Feldman from the Chicago Cubs in hopes that he could bring stability to an at-times shaky starting rotation. In five starts in July Feldman was 2-2 with a 5.12 ERA, but once the calendar turned over to August he really began to find his form. After allowing five runs against the Seattle Mariners on Aug. 3, Feldman, a towering hurler at six-foot seven-inches, has since yet to allow more than three runs in a start — in his last three starts he is 1-1 with a 1.52 ERA, including a complete game shutout against the Chicago White Sox on Sept. 6. In his last 10 starts Feldman has a 5-3 record with a 3.02 ERA. In those starts Feldman has averaged nearly five hits allowed, with an average of two walks and five strikeouts. For the season, the 30-year-old Feldman is 12-10 with a 3.54 ERA. Opponents are batting .229 against him and he has a WHIP of 1.13. Feldman was signed to a one-year, $7 million contract by the Cubs and when it expires at the end of the season, he will become a free agent. But considering the O's traded starter Jake Arrieta and reliever Pedro Strop along with two international signing bonus slots for him, the Orioles will probably try and re-sign him. Feldman's next start should come in the first game of a three-game series against the AL East-leading Red Sox on Tuesday at Fenway Park.
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PLAYERS: Scott Feldman
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Marlee Matlin - Marlee Matlin Reaches Out To Cory Monteith
Picture: Marlee Matlin - Actress Marlee Matlin From ABC's 'Family's Switched at Birth' at the Empire state Building in New York City. - New York, New...
Actress Marlee Matlin has reached out to Cory Monteith as he seeks treatment for substance addiction issues, insisting the road to recovery is "tough" but "worth it".
The Glee star has sought professional help to address his problem, and Matlin has used her own experiences of a drug treatment program to encourage the 30 year old to complete his scheme.
The actress checked into the Betty Ford Clinic in California when she was younger to overcome a drug problem which was spiralling out of control and she took to her Twitter.com page on Monday (01Apr13) to post an inspiring message for Monteith.
She writes, "(My) thoughts (are) with Corey Monteith (sic) from glee (sic)... It's (a) tough road to get well, but having been there, I know it's worth it."


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There's something beautiful about a framed image hanging serenely on a wall. We're extremely proud of our sustainably sourced frames and believe there's really no better way to enhance a stunning photograph. We're pleased as punch to say they've adorned galleries and homes from London to Los Angeles.
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November 18 - December 23, 2011
Reception: November 17, 6:00-8:00 pm
Danese is pleased to announce a group exhibition of Contemporary Ceramics, opening Thursday, November 17, from 6 to 8 p.m. Many of the artists included in the exhibition were part of the Southern California movement, which transformed the perception of ceramics from craft and utility to art and sculpture.
Robert Arneson
Ralph Bacerra
Deborah Butterfield
Wouter Dam
Richard DeVore
Mary Frank
Michael and Magdalena Frimkess
Dimitri Hadzi
Bryan Hunt
Elizabeth King
Jennifer Lee
Satoru Hoshino
John Mason
Ron Nagle
Reuben Nakian
Gustavo Pérez
Ken Price
Adrian Saxe
Goro Suzuki
Cheryl Ann Thomas
Peter Voulkos
Betty Woodman


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Tel: (773)769-0733
North Shore Junior Academy, established in 1955 by the North Shore Seventh-Day Adventist Church, seeks to provide a quality education for grades K-10 in a safe, Christian environment.
It is the philosophy of the church and the school that true education should seek the development of the whole person - the physical, mental, spiritual, and social being.
North Shore has a fantastic group of students coming from a wide range of ethnic backgrounds.
It is our philosophy that each individual is of infinite worth, and our staff of certified teachers is committed not only to helping students grow academically but in all aspects of their lives.
North Shore Junior Academy is a school committed to excellence while maintaining a family atmosphere.
School Overview
|School Membership(s)School Assoc.
|General Conference of the Seventh-Day Adventist Church (GCSDAC)
|Religious Affiliation
|Seventh-Day Adventist
|Grades Offered
|Grades Prekindergarten - 10
Student Body
|Total Students
|100 students
|Student Body Type
|% Students of Color
State avg.: 29%
|Students by Grade
Academics and Faculty
|Total Classroom Teachers
|7 teachers
|Student : Teacher Ratio
National avg.: 13:1
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ChicagoSwedish Covenant Hospital Child Care Center
5145 N California Ave
Chicago, IL, 60625
(773)907-1008Montessori School (Christian)0.1 mi | 25 students | Gr. PK-KG
ChicagoSt. Hilary School
5614 N Fairfield Avenue
Chicago, IL, 60659
(773)561-5885(Roman Catholic)0.5 mi | 312 students | Gr. PK-8
ChicagoLawrence Hall Youth Services
4833 N Francisco Ave
Chicago, IL, 60625
(773)769-3511Special Education School0.5 mi | 77 students | Gr. 9-12
ChicagoLittle Fox Day School
5014 N Lincoln Avenue
Chicago, IL, 60625
(773)561-7206Daycare / Preschool0.5 mi | 20 students | Gr. NS-K
ChicagoLuna Park Preschool And Kindergarten
3250 W Foster Avenue
Chicago, IL, 60625
(773)463-7195Daycare / Preschool0.6 mi | 20 students | Gr. PK-NS
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What do you do when you are dissatisfied with your local public schools? Homeschool your children? Send them to private school? Let's look at your options.
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Add things up and you'll quickly find the answer- math is crucial both in academics and the real world. By following these strategies and following personal training programs, students can uncover their weaknesses and conquer math.


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As the screamin' front man for New Jersey thrash-metal legends Over Kill since the group's formation, Bobby "Blitz" Ellsworth has seen, experienced, and learned a lot in three and a half decades. So what is the one piece of advice that his 2014 self might offer the 1980 Blitz? "Give up the fucking ... More >>
Beer has nothing to prove to you. The sudsy stuff has been around nearly 10,000 years by some estimates, and has played a critical role in building civilizations and maintaining life itself, according to various historians and scientists. Still, like an honors student aiming for valedictorian and ... More >>
Do you know anyone that doesn't like Houston's master MC Fat Tony? If you do, they might be a damned lizard person because no hot-blooded human could hate his new album Double Dragon. That album kicks ass like Billy Lee. What could we learn from such a man in 30 seconds? Let's find out! Rocks Off: ... More >>
Besides "I Wanna Be Sedated" And "Blitzkrieg Bop" Dawkeye via WikipediaIt was ten years ago today that the world lost their first Ramone, when Joey Ramone succumbed to lymphoma in New York City at the age of 49, one month shy of turning 50. The iconic punk frontman would lead the Ramones in ... More >>
Ed. Note: Rocks Off does not advocate trying any of the products mentioned in this article (even if they exist) or, really, following any of Jef With One F's advice about anything at all. When Marilyn Manson put out Mansinthe, that was cute. Then David Lynch put out his own brand of coffee, ... More >>
Since his debut in 1981 as Black Flag's fourth, last and best lead singer, Henry Rollins has been the emissary of intelligent hardcore punk rock and its accompanying ideals. Through his five-year history with the band, from the LPs Damaged to In My Head, he brought an animalistic, poetic spirit t ... More >>
Readers respond to "Wild Ride"
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The Ramones bopped toward history and an unhappy end
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SAN ANTONIO (AP) - For Abby Wambach, marrying partner and professional teammate Sarah Huffman was purely a statement of love, not politics.
OAKLAND (AP) - Oakland Athletics rookie right-hander Sonny Gray has undergone surgery on his left thumb.
SHANGHAI (AP) - Klay Thompson made 5 of 6 3-pointers and scored 25 points to help the Golden State Warriors rout the Los Angeles Lakers 115-89 in a pre-season game in Shanghai on Friday night.
So long, power ratings.
DETROIT (AP) - Mike Napoli's majestic homer began a rare early Boston breakthrough, Junichi Tazawa again bested Miguel Cabrera in a crucial spot and the Red Sox moved within one win of reaching the World Series by edging the Detroit Tigers 4-3 on Thursday night.
ST. LOUIS (AP) - For four straight starts, Michael Wacha has been all but untouchable and appeared totally oblivious to the stakes.
CHICAGO (AP) - A person familiar with the situation says the Chicago Cubs were interviewing Tampa Bay Rays bench coach Dave Martinez for their manager's job.
DALLAS (AP) - Cody Eakin tied it at 12:58 of the second period and rookie Alex Chiasson scored in the shootout to lift the Dallas Stars to a 4-3 win over San Jose on Thursday night that ended the Sharks' perfect start to the season.
SACRAMENTO, Calif. (AP) - DeMarcus Cousins had 29 points, nine rebounds and six steals to lead the Sacramento Kings to their third straight preseason win, a 107-90 victory over the Phoenix Suns on Thursday night.
ARLINGTON, Texas (AP) - Nolan Ryan is leaving the Texas Rangers again, stepping down as CEO role 20 years after ending his Hall of Fame career as a pitcher.
GLENDALE, Ariz. (AP) - The Seattle Seahawks are dominating the NFC West.
SANTA CLARA (AP) - The pain Patrick Willis is feeling in his groin is not enough to keep him from starting in his home state when the San Francisco 49ers face the Tennessee Titans on Sunday.
EAST RUTHERFORD, N.J. (AP) - With an 0-6 record, Tom Coughlin is considering a lot of things to make the New York Giants better.
HOUSTON (AP) - Case Keenum, who hasn't played in a meaningful game since he was in college back in January 2012, will start at quarterback for the Houston Texans this Sunday in one of the tougher environments in the NFL.
PHILADELPHIA (AP) - Eagles quarterback Michael Vick, still recovering from a hamstring injury, does not expect to play in Sunday's game against Dallas.
HUNTERSVILLE, N.C. (AP) - For Tony Stewart, there was no greater joy than escaping his everyday life and climbing behind the wheel of a sprint car. He loves the feel, the way they drive, the purity he finds at all the tiny dirt tracks across the country.
SAN FRANCISCO (AP) - Ian Kennedy pitched seven innings for his third consecutive win, Seth Smith hit a tiebreaking double in the sixth inning and the San Diego Padres beat the San Francisco Giants 4-1 on Friday night.


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5 Ways to Get a Whiter, Brighter Smile
Have you ever heard of the Whiter-Teeth Diet? It's a simple, effective way to get a brighter smile without using harsh whitening remedies or expensive bleaching. All you have to do is look around in your kitchen and change things up just a tad! Here are some awesome tips to get those pearly whites more sparkly.