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About Cory Doctorow
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Cory Doctorow is the author of several novels, two short story collections, and a forthcoming book of essays. He is the co-editor of the popular blog Boing Boing, and the former European Director of the Electronic Frontier Foundation, a civil liberties group that works to keep cyberspace free.
Little Brother is his first novel for young adults, and he hopes it'll inspire you to use technology to make yourself more free.
Doctorow, 36, lives in London, England with his wife and newborn daughter.
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It's about growing up in the near future where things have kept going on the way they've been going, and it's about hacking as a habit of mind, but mostly it's about growing up and changing and looking at the world and asking what you can do about that. The teenage voice is pitch-perfect. I couldn't put it down, and I loved it.
Jo Walton, author of Farthing
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or, let's make this clear!
Alright, stubborn mule that I am, I refuse to give up on this latest "bad batch". So, I need advice/suggestions.
Here is the summary of the situation (see http://www.homebrewtalk.com/showthread.php?t=23139 if you have lot's of time on your hands):
I have a california common ale in the carboy. It is done fermenting. OG 1.050, was 1.008 two weeks ago when I racked it to clearing vessel and as of Yesterday it still is. It has been almost 4 weeks, 2 in primary and 2 in secondary as of this Sunday.
Tastes crappy.
I can not correctly identify the problem, best I can say is it is yeasty. Tastes like 2 other batches (of completely different style beers)I have made recently, but that is another story. It is pretty clear, but there may still be yeast in suspension?
Not knowing what the problem is, are there some things I can do to it before bottling that may help, but certainly won't make it any worse? As it is a lager yeast it could possibly sit longer if I cool it off more, so whatever I do has time to work?
Like using finings? This has been suggested to me but I am under the impression those work best when you are kegging. I bottle. Will this make carbonating difficult/impossible later as there may be no yeast left?
Any other things to try? Am I just being too obstinate and the only real solution is to either dump it or bottle and then drink the $%#*ty beer, or I should say, more %$^#ty beer as that is what I have been drinking. Got 2 1/4 cases to go
If I were smart I would just stop trying to brew. Alas, I am not that smart.
Thanks folks.
Use finings. Cold condition to get any residual yeast out of suspension. Re-pitch when you bottle with the cleanest ale yeast you can find, so that you don't destroy the beer's character. But that's just an idea, I don't know for sure.
What finings do you recomend. I have never used any before. I can get Super Kleer, gelatin, or bentonite (or is that just for wine) at my LHBS.
How cold and how long for conditioning? Coldest stable temp I could manage would be about 40 F in my spare fridge. I have a cold room in the basement that gets colder, but it fluctuates and could go below 30 F.
How much yeast would I pitch and a lager or an ale yeast? I have some dry lager saflager s-23 or ale I have some safale us-56?
I'll try those things, thanks Bird
Wish I knew - I've never used fining before either, just what I've heard about them makes it sound like they would work well for you in this case. The 40° sounds right for cold-conditioning. For yeast, I was just thinking a packet of US-56 or something similar mixed into the bottling bucket. Hell, worth a shot, right?
Hopefully, the *real* experts can chime in soon.
I don't recommend you doing anything...except wait! Where's the recipe?
Let me get this straight...in 1 para you say it's a Cali Ale...in another a lager...which is it? I've had lagers in a carboy over 100 days lagering...you're only at 2 weeks...be sure to keep the temps low (35-50F).
I've had lagers that tasted like rash after 3 weeks and after 3 months in the bottle it tasted damn good.
I had one of my Belgium Dubbels the other night (which have always tasted good) that I bottled in October. It was really great to sip on.
I wouldn't do anything other than let it sit, maybe a month or so longer. Keep your temp down.
Prime and bottle.
I had an ordinary bitter that tasted yeasty after 3 weeks in the bottle. At 5 weeks the yeasty flavor was gone. I used Muntons dry Ale yeast.
I had skimmed over the relative short length of time, so I'm going to jump on the chorus of "leave it along for a while." You aren't anywhere near desperation stage.
cold crash it
[QUOTE=homebrewer_99]I don't recommend you doing anything...except wait! Where's the recipe?
Let me get this straight...in 1 para you say it's a Cali Ale...in another a lager/QUOTE]
It is a california common, uses lager yeast brewed at ale temperatures.
OK, I got it...it's a "Steam-style".
I've lagered over 100 days in a carboy. I wouldn't worry too much about your brew at this point.


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The CCAS didn't report the fact a 15-year-old girl in its care had become pregnant by an adult 35 years ago, court hears.
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A former TTC employee impregnated a 15-year-old girl in the care of the Catholic Children's Aid Society 35 years ago, but the agency never reported the incident to police, a court has heard.
Howard Smith, 61, admitted Tuesday in Ontario Superior Court to having full intercourse three or four times with the girl in 1978 without using a condom, thus impregnating her when he was in his late 20s.
The CCAS became aware of the pregnancy and placed the girl in a home for unwed mothers.
"The CCAS never reported these incidents to any police service," said Crown prosecutor Johnathan Smith, as he read out an agreed statement of facts.
Catholic Children's Aid Society spokesperson Gehna Singh said she could not comment Tuesday because it would take a day to locate the file.
The defendant Smith (no relation to the Crown) stood beside his lawyers John Collins and Robert Warren and pleaded guilty Tuesday to having intercourse with a female under age 16 and another related charge.
It is expected the Crown will withdraw a rape charge when he returns for sentencing March 7.
The prosecutor said he will seek more than two years in prison, while the defence is expected to ask for a conditional sentence.
Both Crown and defence confirmed Smith once worked for the Toronto Transit Commission, but could not say in what role.
The victim was in and out of the society's care from the time she was 6, leaving her in an emotionally fragile state, the prosecutor told Ontario Superior Court Justice Jane Kelly.
The victim, now 49, sobbed and shook in court.
She kept the baby and raised her, initially on her own, and subsequently with a partner. The daughter believed her biological father was the partner until the victim told her the truth when she was a teenager.
In April 2010, the victim contacted police with the allegations.
Toronto police subsequently asked Smith if he would provide a DNA sample. He consented and subsequent tests showed he was the father of the girl.
Police arrested and charged him.
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CRIMES & INCIDENTSScherer to stand trial for parents' deaths
Ernest Scherer III, 31, sat emotionless in an Oakland courtroom Friday as Judge Jeffrey Horner ordered the defendant to stand...Original post made on Aug. 24, 2009
Last comment by Sad, on Aug 25, 2009 at 7:51 pm | 3 comments | 1245 Views
AROUND TOWNKitchen fire goes through the roof
Oil from a stove burst into flames this evening around 7 p.m. shooting through the ceiling to spread to the attic and catching...Original post made on Aug. 24, 2009
Last comment by Jack, on Aug 24, 2009 at 10:26 pm | 1 comment | 948 Views
Neighborhood Invitation - FOR WEDNESDAY APRIL 15 Dear Friends and Neighbors, On Wednesday, April 15, 2009 there will...Original post made by Rick on Apr. 13, 2009
Last comment by George, on Aug 24, 2009 at 10:44 am | 10 comments | 2449 Views
COMMENTS ON STORIESWeekend drowning claims 10-year-old
Tragedy struck a Danville family this weekend, as a 10-year-old girl drowned Saturday in the family's backyard swimming pool....Original post made on Aug. 24, 2009
Last comment by Gino Giordano, on Aug 24, 2009 at 9:16 am | 1 comment | 2606 Views
COMMENTS ON STORIESSRV grad dies in Long Beach shooting
Police in Long Beach are investigating the April 9 fatal shooting of a 21-year-old Danville man. Read the full story...Original post made on Aug. 22, 2009
There are no comments yet. 1254 Views
SCHOOLS & KIDSTrustees OK slight increase in class sizes
Some classrooms may see an extra student or two this year following action by the Board of Education as school administrators...Original post made on Aug. 14, 2009
Last comment by Geoff Gillette, on Aug 21, 2009 at 9:13 pm | 17 comments | 1567 Views
COMMENTS ON STORIESArt Space: The art of the protest - Sign Creation 101 is in order
Overlooked in the sound and fury signifying nut-think that greeted U.S. Sen. Barbara Boxer at her book signing at Rakestraw...Original post made on Aug. 21, 2009
Last comment by Bob K, on Aug 21, 2009 at 4:46 pm | 1 comment | 1757 Views
SCHOOLS & KIDSRemains at dig site now number 22
Work crews excavating for the foundation of the new gymnasium at San Ramon Valley High School have discovered 22 bodies believed...Original post made on Jul. 31, 2009
Last comment by High School Mom, on Aug 21, 2009 at 9:13 am | 13 comments | 1647 Views
COMMENTS ON STORIESA MAC for Alamo
No one is surprised that unincorporated Alamo is about to get a Municipal Advisory Council. County District 3 Supervisor...Original post made on Aug. 21, 2009
Last comment by Hal Bailey, on Aug 21, 2009 at 7:32 am | 1 comment | 1055 Views
AROUND TOWNWhat really can be said in 3 Minutes or less?
Dear Dolores, Various boards, councils, commissions, committees, and taskforces, in their public meetings, restrict citizens...Original post made by Hal Bailey on Aug. 20, 2009
There are no comments yet. 864 Views
COMMENTS ON STORIESAlamo committees face uncertain future
Members of the Alamo Community Council met Thursday, one of their final meetings now that the Contra Costa County Board of...Original post made on Aug. 17, 2009
Last comment by Guy Sallens, on Aug 19, 2009 at 10:18 pm | 7 comments | 1064 Views
AROUND TOWNAlamo woman attacked, car stolen
Deputies from the Contra Costa Sheriff's Department are investigating a home break-in in Alamo today, in which a resident...Original post made on Aug. 10, 2009
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STATE, NATIONAL, INTERNATIONALWeek in Washington yields contacts for Mayor Mike Shimansky
Danville Mayor Mike Shimansky hobnobbed with national leaders including senators Dianne Feinstein, Barbara Boxer and Hillary...Original post made on Aug. 18, 2009
Last comment by Rick Pshaw, on Aug 19, 2009 at 5:17 am | 2 comments | 1403 Views
COMMENTS ON STORIESAce is in place
Ace Hardware opened today in Alamo, to the delight of residents who have wanted another full service hardware store to open...Original post made on Aug. 14, 2009
Last comment by Negative/Positive, on Aug 18, 2009 at 7:27 pm | 13 comments | 1285 Views
SCHOOLS & KIDSRLP Teachers Say Goodbye, and Thanks!
Resurrection Lutheran Preschool in Dublin, affectionately known as RLP is now known as Resurrection Lutheran Child Development...Original post made by Ann Harper on Aug. 18, 2009
There are no comments yet. 1434 Views
AROUND TOWNVets Hall plan nears final approval
Plans for the renovated Veterans Hall are entering the final stretch in the approval process. At a joint meeting Tuesday,...Original post made on Aug. 14, 2009
Last comment by Margreta von Pein, on Aug 17, 2009 at 8:43 pm | 2 comments | 977 Views
STATE, NATIONAL, INTERNATIONALDistrict 10 candidates present views
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Last comment by Marie, on Aug 17, 2009 at 6:30 pm | 2 comments | 1356 Views
AROUND TOWNSchool lunch prices to be decided Tuesday
In an effort to stem losses in the schools' hot lunch program, members of the San Ramon Valley Unified School District Board...Original post made on Aug. 17, 2009
Last comment by Ron, on Aug 17, 2009 at 6:29 pm | 3 comments | 965 Views
CRIMES & INCIDENTSCar totaled at El Cerro under freeway
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Last comment by jo, on Aug 17, 2009 at 10:51 am | 1 comment | 1231 Views
COMMENTS ON STORIESBlackhawk parcel issue may resurface
Some homeowners in Blackhawk are preparing for another fight over the possible sale of vacant lots owned by Blackhawk Country...Original post made on Aug. 10, 2009
Last comment by Sue Talia, on Aug 17, 2009 at 9:44 am | 5 comments | 1002 Views
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Hayward NAACP officials threaten blog posters
By Tim Hunt | 21 comments | 1,534 views
Not so speedy trial
By Roz Rogoff | 4 comments | 1,221 views


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MOD MOD MOD! I'm so confused please help! Okay, so lately my body has been acting weird. My chest flutters a lot and when I get up in the morning, my breathing is all wheezing. I got my period yesterday, too and it's heavier than normal. Also, I am tired all the time and have to pee a lot. I'm not sure what's up, but I'm training for Cross Country in the fall and I was wondering if this could all affect my running. Plus, I can't run my usual 3-4 miles with the team anymore, I've started to lag behind or walk, and I feel like I might upset my coach because I 'm usually one of the faster girls. Should I go see a doc?
Hey! the only way to really feel reassured is to talk to your doctor about all of these questions To be honest, that's what we mods just have to tell you guys when you come to us with any health concerns. You may very well be fine, but since we're not doctors and we can't even see you face to face, it's not for us to tell you what's fine and what isn't. You know your body. Trust your instincts and talk to your doc!
by flower_power_99 on 7/11/2013 7:41:25 PM
MOD MOD MOD! I've asked the same question twice but no answer! The question was: My BF French kisses me.. a lot. And I don't really like it. I mean I like some tongue every once in a while but not every time. How do I ask him (sweetly, of course!) to not French kiss me all the time? Please help me!!!! xx.
hey! You just have to come out and say, "hey can we try it this way instead?" and then lead by example of what you want. Don't worry, it's not mean to be honest with your boyfriend, you'd want him to be honest with you, right?
by nialler_4_ever on 7/11/2013 7:02:45 PM
So that means that on July 30th they will tell us what to do to enter? I got the magazine in the mail yesterday.
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That's right! The deets on how to enter will be posted on July 30th. Keep coming back for more info and hold on to the current issue so you have it when you enter.
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MOD MOD MOD, Ok! Now Im definatley getting my mom to get me subscribed!!!!!! Yay!!!! Love you GirlsLife! <3
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SAME!! @lucy143247
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When do you think I will receive this issue? I can't wait after seeing this article!!
Hey girlie, you should have it by the end of the month!
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omg im soooo excited for this issue of GL!!! I love love love Ariana Grande!!!!!!!!!!!!<3
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Teenage girl...and assassin nun? Meet Annith in Mortal Heart
Mortal Heart—the third and final chapter in the His Fair Assassin trilogy—follows a trio of teen girls trained in the dark arts of spying and murder. CLICK HERE to catch up on the first two books...and get a sneak peek at the gripping conclusion in Mortal Heart.


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Our Bodies, Our Stories,
Our Communities
Well Arts Institute is a nonprofit, arts organization that explores the health of our community and its members through the reflective lens of the arts.
A Warm Farewell
After an adventurous and impactful four years as Well Arts' Executive Director, I have made the bittersweet decision to resign and transition to new roles in new arenas.
As Artistic/Executive Director of Well Arts, I've been honored by the generosity of the participants who have opened their experiences and thoughts with me to create beautiful art. I've been lucky to work with amazing actors, helping them collaborate with people with amazing stories.
I've been humbled by the enthusiasm I encounter when I tell people what we do, and the passion with which so many people have shared expertise, time, money, and resources to make sure that ordinary people's stories get on stage. I have loved working with the participants, the actors, and so many supporters—it's changed my life.
The Well Arts board will continue to steward the organization and are in the midst of building a new plan to move the organization forward. I have every confidence they will make Well Arts stronger than ever. The board would love to hear feedback from those of you who've been involved with Well Arts in the past, or who are interested in getting involved.
If you have questions about programming, organizational vision, donations or anything else, our new board chair Julie Mae Muiderman will be happy to get in touch with you. Click here to email Julie Mae now.
Soon a number of volunteer opportunities will be made available, so please contact board member Charmian Creagle if you're interested in helping out. Click here to email Charmian now.
Well Arts' commitment to knitting together community through the arts is thriving. We're so excited to be offering the following projects as we head into 2015:
▪ "Stories from p:ear" written and performed by homeless youth through a partnership with p:ear, performing during the Fertile Ground Festival in January 2015.
▪ "Fierce Love", stories written by mothers caregiving for children with Cerebral Palsy, through a partnership with United Cerebral Palsy of Oregon and SW Washington, workshops starting November 2014 and performing in March 2015.
▪ "Coming out of the Shadows" written by veterans surviving military sexual trauma, with Returning Veterans Project and Wise Counsel and Comfort, workshops starting January 2015, performing in May 2015.
▪ "Reunion Writers" stories written by Well Arts Participants from 2000–2010, performing in June 2015.
Stay with us. It's about to get even more awesome! And thank you for letting me be a part of your world.
Katy Liljeholm, Outgoing Artistic/Executive Director
Amazon Donation Campaign
When you shop at AmazonSmile, Amazon donates 0.5% of the purchase price to Wells Arts Institute.
Bookmark the link http://smile.amazon.com/ch/93-1311041 and support us every time you shop.
Member since 2005
Creativity and Wellness
Updated on 2014-11-26T20:44:15+00:00, by .


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Ciler "Error" @ Soze Gallery, West HollywoodJuxtapoz // Wednesday, November 12, 2014
This Saturday, November 15th, Soze Gallery will present new works from Mexico City artist CILER, also known as, Alexis Mata. The exhibition entitled, "ERROR", marks the first solo show in the United States by CILER. This dramatic collection of work will mark the finale to the 2014 season at Soze Gallery.
Scene Report: Bay AreaGraffiti // Tuesday, November 11, 2014
Each week we feature updates on current graffiti scenes in a number of major U.S. cities with the help of a few select photographers. Gordon Gekkoh delivers this week's Bay Area Scene Report.
Keith Haring: The Political Line @ de Young MuseumJuxtapoz // Tuesday, November 11, 2014
Keith Haring: The Political Line had its US premiere at the de Young and is the first major Haring show on the West Coast in nearly two decades. Many of the works are on loan from the Keith Haring Foundation, New York, with supplemental loans from public and private collections. Several pieces have not been published or on public view since the artist's death, in 1990.
Pink: A series by Prue StentErotica // Tuesday, November 11, 2014
Let's take a moment to celebrate the color pink, in all its glory, in all its rare use in the natural world or art in general. For some reason, seeing this great series of Pink by Melbourne's Prue Stent made us realize just how rare pjnk is used, or better yet, how rare it is that pink is used well. From Staged Photography, "The themes of her photography center around femininity and the struggle of identity in women. The color pink is used to represent femininity either physically or emotionally throughout her work."
Jen Mann "Q&A" @ Neubacher Shor Contemporary, TorontoJuxtapoz // Tuesday, November 11, 2014
We have been excited about the work of Jen Mann for most of the year, especially because of her inclusion in our Juxtapoz Hyperreal book and her newest body of work that is set to open on November 20, 2014 at Neubacher Shor Contemporary in Toronto. We have a feature with Mann in the current December 2014 issue, with much of her new work being previewed there.
Almost There (Official Trailer)Juxtapoz // Tuesday, November 11, 2014
Though it has been happening a bit more in the past few years, it's not everyday that a prolific "outsider" artist is discovered or shall I say uncovered. By uncovered I almost mean literally because documentarians Aaron Wickenden and Dan Rybiky found this gentleman buried in his own squalor, happily and delusional-y painting away. Almost There digs deep and goes further than your average artist profile film. Check out the trailer below and start digging under rocks in your own town.
Neo Rauch "At the Well" @ David Zwirner Gallery, NYCJuxtapoz // Tuesday, November 11, 2014
David Zwirner is pleased to present an exhibition of new works by Neo Rauch, on view at 533 West 19th Street in New York. At the Well brings together small and large format paintings that expand the artist's unique iconography of eccentric figures, animals, and hybrids within vaguely familiar but imaginary settings.
In the Half LightPhotography // Tuesday, November 11, 2014
In his series "In the Half Light," British photographer Joe Dixey explores the faint light cast by twilight and the moment it creates between light and total darkness. Dixey's images portray the subject matters in a moment of stillness where they are visually comprised of silhouettes and faint detail.
David Walker "A BLANK CANVAS IS A WHITE FLAG" w/ Lawrence Alkin Gallery @ Hoxton Gallery, LondonJuxtapoz // Tuesday, November 11, 2014
David Walker returns to the city where he first made his mark with a major solo show 'A Blank Canvas is a White Flag'. Walker's first London gallery show in three years, sees this incredibly talented urban artist presenting a fresh new take on his signature portrait style in a show named after a mantra coined by the artist himself; which refers to the creative battle an artist wages to create work in today's climate in the face of conspiring forces both internal and external.
Drawings by Boicu MarinelaJuxtapoz // Tuesday, November 11, 2014
We happened upon some drawings by Romanian artist Boicu Marinela last night and are enjoying the wiry and doodle-like but precise nature of the lines in her work. Marinela studied painting and graphic arts at a school for arts called "Otav bancila."


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Dairy economists analyze Dairy Security Act vs. Goodlatte-Scott
In dairy politics, DairyBusiness Update (DBU) reports that a team of university dairy economists have compiled a new report comparing two major dairy policy proposals. The paper, "Goodlatte-Scott vs. the Dairy Security Act: Shared Potential, Shared Concerns and Open Questions," reports analysis and expected short-term impacts of the Dairy Security Act (DSA) and the Goodlatte-Scott Amendment (G-S).
Academic in nature, the report suggest both DSA and G-S are effective in providing catastrophic risk insurance and revenue enhancement for dairies with stable and moderately growing milk marketings.
If dairy producer participation rate is high and the impact on consumer demand for milk is low, DSA's Dairy Market Stabilization Program (DMSP) has the potential to reduce government outlays and accelerate margin recovery during low-margin periods. G-S effective catastrophic margin insurance for aggressively growing farms is limited due to the fixed production history. However, more complete margin risk protection may still be possible using private risk markets to complement government provided insurance.
The primary focus of the analysis was the proposals' short-term effects. The long-term impacts on the growth of milk supply, dairy exports and liquidity of private dairy risk markets were not addressed.
National Milk says the analysis "demonstrates that the DSA provides the most effective economic safety net for farmers." NMPF's Jerry Kozak said "The assessment, generated by the Midwest Program on Dairy Markets and Policy, shows DSA provides catastrophic risk insurance, helps enhance farmer revenue, and does so in a way that minimizes government outlays."
He added that the report "debunks any concerns that the DSA's market stabilization element will hinder the growth of our industry or detrimentally affect the future of the dairy business. This says those fears are unfounded," he said. "In fact, we need the DSA in order to give our farmers a future."
Processors charge that the study "clearly shows consumers and taxpayers will bear the brunt of bad dairy policy." An IDFA press release stated; "The study confirms what the Congressional Research Service has reported, the Dairy Security Act will raise milk prices and force consumers to pay more for dairy products."
According to the authors, "DMSP is a supply management-type program designed to enhance milk prices. The DMSP aims to reduce the milk supply and thereby enhance milk prices by imposing income penalties on dairy farmers shipping milk over their assigned production level."
"Goodlatte-Scott is a more responsible approach to a government-funded Farm Bill," said IDFA's Jerry Slominski. "It provides an effective safety net, according to the Congressional Budget Office, without also imposing an anti-consumer 'growth management' program on the dairy industry. The reality is that farmers can have effective risk management tools without the government getting involved in limiting production and forcing consumers to pay more for dairy products, a key provision of the Peterson plan."
Immigration policy introduced
In another crucial policy front; a bipartisan immigration policy reform proposal introduced in the Senate was praised by agricultural and dairy leaders. DBU's Dave Natzke reported in Friday's DairyLine that "The proposal introduced in the Senate on Wednesday (April 17) was called "historic" by representatives of major dairy, cooperative, fruit and vegetable grower and farm labor organizations during a joint press conference held this week.
Members of the Agriculture Workforce Coalition said the proposal addresses the major needs of U.S. farmers and workers and helps fix a broken immigration policy that is leading to shortages of workers to produce, harvest and pack the nation's food supply.
National Milk's Jerry Kozak participated in the press conference and identified four key pieces of the proposal essential to dairy producers, covering both current and future immigrant workers.
They include creation of a "blue card" for experienced but undocumented workers, providing them legal protection from deportation; and creation of a new visa program that will provide a stable supply of legal workers in the future.
The bill would create a system whereby dairy and other agricultural producers can recruit and hire new workers, either on a contract or at-will basis, from a pool of applicants. The visa program would also do away with current visa requirements that only address the needs of seasonal occupations, since dairy farming is a 365-day-a-year job.
The bill would also create specific categories of agricultural workers, and establish minimum wages for each group based on the skills required, and provide other worker protections. And, the "blue cards" would be extended to workers spouses and children to help immigrant labor families stay together.
The views and opinions expressed in this column are those of the author and not necessarily those of Farm World. Readers with questions or comments for Lee Mielke may write to him in care of this publication.
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What *** michael jordan wearing? - tumblr, "i can accept failure, everyone fails at something. but i can't accept not trying." - michael jordan ---- twitter: @wtfismjwearing. Culture life news | culture life news: blog , Culture of life news: the blog is mightier than the sword. ruthless analysis of history and modern events.. Yavmamemo (yavmamemogames@gmail.) deviantart, Art - community of artists and those devoted to art. digital art, skin art, themes, wallpaper art, traditional art, photography, poetry / prose. art prints..
This england - trailer - youtube, Www.shanemeadows..uk trailer shane meadows' latest film, england (released uk cinemas 27th april 2007).. http://www.youtube.com/watch?v=H0jkv2bRFgQ Allie wired, Allie wired entertainment blog. ll find celebrity news, music news, videos, movie news trailers, fashion related news.. http://www.allieiswired.com/ This white privilege - tumblr, White privilege hard ( white people) , compilation album white privilege' greatest hits. submit examples. flavors . http://thisiswhiteprivilege.tumblr.com/


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Rap mogul Dr. Dre is not the only successful producer going back to his past career as a deejay as former Cash Money Records artist Mannie Fresh has revealed his recent run at stepping behind the turntables.
According to Fresh, he has been deejaying at multiple spots as of late.
"I deejay [DJMannieFresh.com]. I deejay my a** off, dude. Like, I'm all over the place these days. That's what I started from, and that's where I'm at right now. And, the cool thing about the deejay game is it tells you everything that's going on in music, what people liking. Before the Bonnaroo thing was sold as it was a reunion for me and [Lil] Wayne, really I was hired to deejay at Bonnaroo. It just so happens he was there as well as me." (Hip Hop DX)
Recently, Dr. Dre talked about wanting to go back into deejaying.
It's no secret that Dre has been fine-tuning is long-awaited Detoxalbum, but what fans may not know is that the former N.W.A producer has at least thought about returning to the DJ booth. "I've actually been talking about it a little bit; dusting my hands off and getting back in the DJ scene," he said. "We'll see what's up with that in the future." (MTV)
Last year, fellow hip-hop producer Lil Jon talked about stepping behind the turntables on the road.
"Eventually TVT folded and I got off the label," Jon explained in an interview. "I got signed to Universal Republic about a year ago and I went back to the studio and started working on the album again and I had a whole new energy, new vibe, from being on the road deejaying and just from taking some time off, clearing my mind. So now I'm done, we're officially ready. It's not like, 'We're almost done,' I'm just working on like one or the last two songs but all of my vocals are done except for one song. [It's still called]Crunk Rock." (DJ Ekin)
Emcee-turned-deejay DJ Stimulus recently talked to SOHH about falling in love with the turntables.
"The reason I fell into deejaying is because I love music so much. Back at the crib, I found it was more interesting to play the records than listen to the radio with the commercials and hearing the songs go in a certain order. I've been deejaying for quite a long time and for the most part, depending on the year and depending on the audience, some people know me more [for one entity as opposed to] the other. Deejaying goes almost as far back as rhyming for me. It's really about my love for the culture. I love making music and I love music that other people make which is where the deejay in me comes about." (SOHH Guest Star)
Check out some recent Mannie Fresh footage below:


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Two tools that should be in every developer's arsenal are Fiddler and Beyond Compare.More...
Feel free to skip past this, If you'd rather cut to the chase and want the summary of my thoughts and opinion about the movie feel free to skip to the Tron Legacy: My Opinion portion of this post. Otherwise I'm going to ramble quite a bit talking about some Tron History and also provide some details on how and why the movie is and always will be #1 on my list of favorites. My Disclaimer: As such, odds are that you might as well understand this is going to be a positive review as I am biased to begin with.
Eric Brown has been developing software and tinkering with computers both as a hobby and professionally for well over twenty years. Currently he's expanding his horizons by learning the "other side" of coding by exploring penetration testing, white/grey and black hat hacking to help build more secure software, networks and systems. He's attending various local events in an attempt to get to know other ethical hackers in the area. He currently owns several various hacking, networking, reverse engineering, malware analysis and forensics books as well as maintains an active subscription to "Pen Tester Academy". He's also studying what is new in the .NET Framework 4.5.2 as well as learning Python, Assembly and spending time in Linux.


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Ocean Drive Beach House Rental Photos and Description
Four Bedrooms, 2.5 Baths with spacious living areas
Classic beach house that has been fully updated, without losing the charm of the Ocean Drive style. From the wood paneled walls to the large bedrooms and sitting areas, you will love the nostalgic, yet comfortable feeling you get from staying in Sand-Bar.
Just on the third row of houses from the beach, it is a short walk to plant yourself on one of the least crowded stretches of beach in North Myrtle. In the Tilghman section, you are surrounded by private homes and your view to the ocean is not obstructed by high rise condo buildings nor do you have to squeeze into a tiny spot on the beach. Spread your blanket and chairs, relax and watch the waves roll in.
Main Street Ocean Drive is just 7 blocks away - a great walk on a moonlit night after enjoying the amusement rides or arcade downtown. Or, take a short bike ride to grab lunch or do some shopping. Sand-Bar is conveniently nestled in a quaint section of the beach ,yet close to everything. But, be warned, when you leave the house, you will yearn for the sanctuary and quiet of Sand-Bar.
Inside the house you will find two big screen tv's, two separate family areas a fully stocked kitchen, a sun deck for relaxing, a covered deck downstairs and two enclosed porches. Two of the bedrooms are large enough to sleep a family of four in each, with two queen beds. Now that's a big bedroom!
Sand-Bar has been lovingly cared for by a single owner family since it was built in 1954. Close attention has been paid to comfort and style since we use the house all but a few weeks a year when it is available for rent.
- Suitability:
- Minimum Age Limit for Renters
- children welcome
- non smoking only
- pets considered
- wheelchair inaccessible


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Molecular pharmaceutics [journal]
2337 results
- Cellular uptake of coumarin 6 under microfluidic conditions into HCE-T cells from nanoscale formulations. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 20.
- AbstractPublisher Full Text
In vitro studies of ocular bioavailability of active pharmaceutical ingredients (API) from colloidal drug delivery systems do not consider physiological shear stress generated by eyelid wiping and tear flow. The present study introduces a live cell imaging approach which enables the investigation of model drug uptake from various formulations under shear stress by using custom-made microchannels for the cultivation of human corneal epithelial cells (HCE-T). Coumarin-6 (C-6) was used as a model API incorporated into solid lipid nanoparticles and liposomes, and as an aqueous crystalline suspension. Confocal laser scanning microscopy visualized C-6 uptake into HCE-T cells in a time-resolved manner with an applied shear stress of 0.1 Pa. Static conditions were also studied for comparative purposes. Additionally, solid lipid nanoparticles (SLN) were labeled with a fluorescent phospholipid to check whether C-6 uptake was associated with SLN incorporation into the cells. Results: Intact SLN were not incorporated into the cells, i.e., C-6 was passively redistributed from SLN to lipophilic cellular compartments. C-6 was enriched up to a given limit in HCE-T cells within 5 minutes of contact with the dispersions both under static and under flow conditions. The C-6 delivery rate from liposomes was superior to that from SLN whereby the suspension exhibited the lowest rate. C-6 release rates were comparable for static and flow conditions. Alternate flushing with formulations and buffer revealed that cells accumulated C-6. The results suggest that combining microfluidics with live cell imaging provides a valuable option for in vitro studies of ocular drug delivery.
- Nucleolar Targeting by Platinum. p53-independent Apoptosis Follows rRNA Inhibition, Cell-cycle Arrest and DNA Compaction. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 18.
- AbstractPublisher Full Text
TriplatinNC is a highly positively charged, substitution-inert derivative of the phase II clinical anticancer drug, BBR3464. Such substitution-inert complexes form a distinct subset of polynuclear platinum complexes (PPCs) interacting with DNA and other biomolecules through "non-covalent" interactions. Rapid cellular entry is facilitated via interaction with cell surface glycosoaminoglycans and is a mechanism unique to PPCs. Nano-scale secondary ion mass spectrometry (NanoSIMS) showed rapid distribution within cytoplasmic and nucleolar compartments, but not the nucleus. In this paper, the downstream effects of nucleolar localization are described. In human colon carcinoma cells, HCT116, the production rate of 47S rRNA precursor transcripts was dramatically reduced as an early event after drug treatment. Transcriptional inhibition of rRNA was followed by a robust G1 arrest, and activation of apoptotic proteins caspase-8, -9, -3, and PARP-1 in a p53-independent manner. Using cell synchronization and flow cytometry, it was determined that cells treated while in G1 immediately arrest , but cells treated in S or G2 successfully complete mitosis. Twenty-four hours after treatment, the majority of cells finally arrest in G1, but nearly one-third contained highly compacted DNA; a distinct biological feature that cannot be associated with mitosis, senescence, or apoptosis. This unique effect mirrored the efficient condensation of tRNA and DNA in cell-free systems. The combination of DNA compaction and apoptosis by TriplatinNC treatment conferred striking activity in platinum-resistant and/or p53 mutant or null cell lines. Taken together, our results support that the biological activity of TriplatinNC reflects reduced metabolic deactivation (substitution-inert compound not reactive to sulfur nucleophiles), high cellular accumulation and novel consequences of high-affinity non-covalent DNA binding - producing a new profile and a further shift in the structure-activity paradigms for anti-tumor complexes.
- Improving the Therapeutic Index in Cancer Therapy by Using Antibody-Drug Conjugates Designed with a Moderately Cytotoxic Drug. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 25.
- AbstractPublisher Full Text
The antibody-drug conjugate (ADC), IMMU-130, of the moderately cytotoxic topoisomerase I inhibitor, SN-38, and the CEACAM5-targeted humanized antibody (mAb), labetuzumab, was evaluated in model systems of human colon carcinoma and in phase I clinical trials of heavily pretreated patients with metastatic colorectal cancer. The conjugate, designed with a near-homogeneous drug substitution of 7-8 SN-38/mAb and with a linker that released 50% of the drug in ∼20 h, showed significant antitumor effects compared to a nontargeted ADC in human tumor xenografts, which could be augmented in combination with bevacizumab. The advantage of fractionated dosing was demonstrated, with potential implications for the clinical dosing schedule. Biodistribution comparing IMMU-130 with labetuzumab showed that the conjugate cleared somewhat faster from the blood, but this did not affect tumor uptake and retention. The use of an ultrastable linker in the conjugate design abrogated antitumor effects. A tolerability study in rabbits showed a high safety margin, with no-observed-adverse-effect level (NOAEL) corresponding to a cumulative human-equivalent protein dose of 40-60 mg/kg. The preclinical findings appear to be corroborated in two phase I clinical trials, with high tolerability and evidence of antitumor activity, including objective responses. The impact of the ADC design on the utility of IMMU-130, tailored to a poorly internalizing target, is discussed.
- Serial in Vivo Imaging Using a Fluorescence Probe Allows Identification of Tumor Early Response to Cetuximab Immunotherapy. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 24.
- AbstractPublisher Full Text
Cetuximab is an antiepidermal growth factor receptor (EGFR) monoclonal antibody that has received the approval of the Food and Drug Administration (FDA) for cancer treatment. However, most clinical studies indicate that cetuximab can only elicit positive effects on a subset of cancer patients. In this study, we investigated whether near-infrared fluorescence (NIRF) imaging of tumor vascular endothelial growth factor (VEGF) expression could be a biomarker for tumor early response to cetuximab therapy in preclinical wild-type and mutant tumor models of the KRAS gene. The treatment efficacy of cetuximab was determined in both HT-29 (wild-type KRAS) and HTC-116 (mutant KRAS) human colon cancer models. A VEGF-specific optical imaging probe (Dye755-Ran) was synthesized by conjugating ranibizumab (an anti-VEGF antibody Fab fragment) with a NIRF dye. Serial optical scans with Dye755-Ran were performed in HT-29 and HTC-116 xenograft models. By using longitudinal NIRF imaging, we were able to detect early tumor response on day 3 and day 5 after initiation of cetuximab treatment in the cetuximab-responsive HT-29 tumor model. Enzyme-linked immunosorbent assay (ELISA) confirmed that cetuximab treatment inhibited human VEGF expression in the KRAS wild-type HT-29 tumor but not in the KRAS mutant HCT-116 tumor. We have demonstrated that the antitumor effect of cetuximab can be noninvasively monitored by serial fluorescence imaging using Dye755-Ran. VEGF expression detected by optical imaging could serve as a sensitive biomarker for tumor early response to drugs that directly or indirectly act on VEGF.
- Comparing Multi-Label Classification Methods for Provisional Biopharmaceutics Class Prediction. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 14.
- AbstractPublisher Full Text
The biopharmaceutical classification system (BCS) is now well established and utilised for the development and biowaivers of immediate oral dosage forms. The prediction of BCS class can be carried out using multi-label classification. Unlike single label classification, multi-label classification methods predict more than one class labels at the same time. This paper compares two multi-label methods, binary relevance and classifier chain, for provisional BCS class prediction. Large datasets of permeability and solubility of drug and drug-like compounds were obtained from the literature and were used to build models using decision trees. The separate permeability and solubility models were validated and an BCS validation set of 127 compounds where both permeability and solubility were known was used to compare the two aforementioned multi-label classification methods for provisional BCS class prediction. Overall, the results indicate that the classifier chain method, which takes into account label interactions, performed better compared to the binary relevance method. This work offers a comparison of multi-label methods and shows the potential of the classifier chain multi-label method for improved biological property predictions for use in drug discovery and development.
- Trantinterol, a novel β2-adrenoceptor agonist non-competitively inhibits P-glycoprotein function in vitro and in vivo. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 12.
- AbstractPublisher Full Text
P-glycoprotein (P-gp)-mediated drug-drug interactions are important factors causing adverse effects of drugs in clinical use. The aim of this study was to determine whether trantinterol (also known as SPFF), a novel β2-adrenoceptor agonist, was a P-gp inhibitor or substrate. The results showed that trantinterol was not a substrate of P-gp but increased rhodamine 123 (Rho 123) uptake by MDCK-MDR1 cells and decreased the efflux transport of both Rho 123 and cyclosporine A (CsA) in bi-directional transport studies across MDCK-MDR1 cell monolayers. This suggested that trantinterol was a P-gp inhibitor but not a P-gp substrate. The mechanism of inhibition was investigated in the P-gp-Glo assay system where it was found that trantinterol inhibited P-gp ATPase activity in a dose-dependent manner. A subsequent study using the antibody binding assay with the conformation-sensitive P-gp-specific antibody UIC2 confirmed that trantinterol decreased UIC2 binding at 10 μM in contrast to the competitive inhibitor, verapamil. This suggested that trantinterol was a non-competitive inhibitor of P-gp. Finally, a pharmacokinetic study in rat showed that trantinterol significantly increased the area under the plasma concentration-time curve (AUC) and maximum plasma concentration (Cmax) of digoxin and paclitaxel (PAC), and the Cmax of cyclosporine A (CsA). In summary, trantinterol is a potent non-competitive P-gp inhibitor which may increase the bioavailability of other P-gp substrate drugs co-administered with it.
- Specific Ion and Buffer Effects on Protein-Protein Interactions of a Monoclonal Antibody. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 12.
- AbstractPublisher Full Text
Better predictive ability of salt and buffer effects on protein-protein interactions requires separating out contributions due to ionic screening, protein charge neutralization by ion bind- ing, and salting-in(out) behaviour. We have carried out a systematic study by measuring protein-protein interactions for a monoclonal antibody over an ionic strength range of 25 to 525 mM at 4 pH values (5, 6.5, 8, 9) in solutions containing either sodium chloride, calcium chlo- ride, sodium sulfate, or sodium thiocyante. The salt ions are chosen so as to represent a range of affinities for protein charged and non-charged groups. The results are compared to effects of various buffers including acetate, citrate, phosphate, histidine, succinate, or tris. In low ionic strength solutions, anion binding affinity is reflected by the ability to reduce protein-protein repulsion, which follows the order thiocyanate > sulfate > chloride. The sulfate specific effect is screened at the same ionic strength required to screen the pH dependence of protein-protein interactions indicating sulfate binding only neutralizaes protein charged groups. Thiocyanate specific effects occur over a larger ionic strength range reflecting adsorption to charged and non-charged regions of the protein. The latter leads to salting-in behaviour and, at low pH, a non-monotonic interaction profile with respect to sodium thiocyanate concentration. The ef- fects of thiocyanate can not only be rationalized in terms of neutralizing double layer forces indicating the presence of an additional short-ranged protein-protein attraction at moderate ionic strength. Conversely, buffer specific effects can be explained through a charge neutral- ization mechanism, where buffers with greater valency are more effective at reducing double layer forces at low pH. Citrate binding at pH 6.5 leads to protein charge inversion and the for- mation of attractive electrostatic interactions. Throughout the report, we highlight similarities in the measured protein-protein interaction profiles with previous studies providing evidence that the behaviour is universal to all proteins.
- Putative Transmembrane Domain 6 of the Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) Influences Transporter Substrate Binding, Protein Trafficking, and Quality Control. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 20.
- AbstractPublisher Full Text
The human organic anion transporting polypeptides (OATPs) are a family of important membrane proteins that mediate the cellular influx of various anionic substances including clinically important drugs. Transmembrane domain 6 (TM6) is a distinctive consensus "signature" common to all OATPs. Two naturally occurring variants were previously identified in TM6 of the important transporter OATP1A2; these variants may be associated with suboptimal drug influx into cells. Because of the potential importance of TM6 in drug efficacy, this study investigated its role in substrate uptake by OATP1A2. Single amino acid replacements were introduced into TM6 of OATP1A2 (residues 245-266) by alanine-scanning mutagenesis. Uptake assays, biotinylation and immunoblotting were used to assess the function and expression of OATP1A2 and its mutants after overexpression in HEK293 cells. Uptake of the model substrates estrone-3-sulfate and methotrexate by OATP1A2 mutants carrying amino acid replacements within the TM6 subregions of 245-248 and 261-266 was impaired, while transport function was largely retained by other mutants. From kinetic, biotinylation, and immunoblot analysis the diminished function of the 245-248 and 261-266 mutants was due primarily to decreased plasma membrane and total cell expression and also to a less extent, impacted by altered substrate binding. Further experiments with proteasomal or lysosomal inhibitors were consistent with impaired maturation and impaired plasma membrane insertion of several mutants of OATP1A2 within the subregions of 245-248 and 261-266. In addition, the finding that total cellular expression, but not plasma membrane expression, was less impaired for the W245A and W246A mutants suggests that these two TM6 residues might be involved in membrane targeting of OATP1A2. These findings implicate the TM6 subregions of 245-248 and 261-266 in substrate binding, protein trafficking, and quality control of OATP1A2.
- Targeted Decationized Polyplexes for siRNA Delivery. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 20.
- AbstractPublisher Full Text
The applicability of small interfering RNA (siRNA) in future therapies depends on the availability of safe and efficient carrier systems. Ideally, siRNA delivery requires a system that is stable in the circulation but upon specific uptake into target cells can rapidly release its cargo into the cytoplasm. Previously, we evaluated a novel generation of carrier systems ("decationized" polyplexes) for DNA delivery, and it was shown that folate targeted decationized polyplexes had an excellent safety profile and showed intracellular triggered release upon cell specific uptake. Targeted decationized polyplexes consist of a core of disulfide cross-linked poly(hydroxypropyl methacrylamide) (pHPMA) stably entrapping nucleic acids and a shell of poly(ethylene glycol) (PEG) decorated with folate molecules. In the present study, the applicability of folate targeted decationized polyplexes for siRNA delivery was investigated. This required optimization of the carrier system particularly regarding the cross-linking density of the core of the polyplexes. Stable and nanosized siRNA decationized polyplexes were successfully prepared by optimizing the cross-link density of their core. Upon incubation in human plasma, a significant portion of siRNA remained entrapped in the decationized polyplexes as determined by fluorescence correlation spectroscopy (FCS). When tested in a folate receptor overexpressing cell line stably expressing luciferase, Skov3-luc, sequence specific gene silencing was observed. As expected, neither interference on the intrinsic luciferase expression nor on the cell metabolic activity (determined by XTT) was induced by the free-polymer or the siRNA polyplexes. In conclusion, targeted decationized polyplexes are safe and stable carriers that interact with the targeted cells and rapidly disassemble upon cell entry making them promising siRNA delivery systems.
- Highly Viscous Antibody Solutions Are a Consequence of Network Formation Caused by Domain-Domain Electrostatic Complementarities: Insights from Coarse-Grained Simulations. [JOURNAL ARTICLE]
- Mol Pharm 2014 Nov 20.
- AbstractPublisher Full Text
Therapeutic monoclonal antibody (mAb) candidates that form highly viscous solutions at concentrations above 100 mg/mL can lead to challenges in bioprocessing, formulation development, and subcutaneous drug delivery. Earlier studies of mAbs with concentration-dependent high viscosity have indicated that mAbs with negatively charged Fv regions have a dipole-like quality that increases the likelihood of reversible self-association. This suggests that weak electrostatic intermolecular interactions can form transient antibody networks that participate in resistance to solution deformation under shear stress. Here this hypothesis is explored by parametrizing a coarse-grained (CG) model of an antibody using the domain charges from four different mAbs that have had their concentration-dependent viscosity behaviors previously determined. Multicopy molecular dynamics simulations were performed for these four CG mAbs at several concentrations to understand the effect of surface charge on mass diffusivity, pairwise interactions, and electrostatic network formation. Diffusion coefficients computed from simulations were in qualitative agreement with experimentally determined viscosities for all four mAbs. Contact analysis revealed an overall greater number of pairwise interactions for the two mAbs in this study with high concentration viscosity issues. Further, using equilibrated solution trajectories, the two mAbs with high concentration viscosity issues quantitatively formed more features of an electrostatic network than the other mAbs. The change in the number of these network features as a function of concentration is related to the number of pairwise interactions formed by electrostatic complementarities between antibody domains. Thus, transient antibody network formation caused by domain-domain electrostatic complementarities is the most probable origin of high concentration viscosity for mAbs in this study.


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Rick Ross had cameras follow him around last week during Super Bowl Weekend. From the Def Jam 30 party to Marquee to Greenhouse and a ...Read More
ScHoolboy Q Releases 'Oxymoron' World Tour Dates
ScHoolboy Q took to Twitter to release the dates for his forthcoming Oxymoron World Tour. The tweet read "#OXYMORON world tour!! 67+ dates" Q will be going on tour alongside Vince ...Read More
Bernard Hopkins Says Fight With Cam'ron Would Be A Demo
"It be a demo" That was the former middleweight champ Bernard Hopkins response to Cam'ron for name dropping him in Cam's new record called "Humphrey." The song is off Killa's ...Read More
Peeda Pan On 'Bang 3′: "Kanye Will Definitely Be On Keef's Album"
Chief Keef received a big opportunity last year when Kanye West tapped his services for Yeezus. "Hold My Liquor" was a fan-favorite off his sixth ...Read More
50 Cent Wants To Get Hip-Hop More Involved In NASCAR
Earlier today it was announced that 50 Cent partnered his SMS Audio line with NASCAR. The venture is with Swan Racing and they will advertise 50′s company ...Read More
M.O.P. Says G-Unit Might Be On Their Next Album
M.O.P. was interviewed by DJ Whoo Kid today. The Mash Out Posse updated fans on the status of their upcoming projects, working with Mobb Deep for ...Read More
Raekwon Shows A Different Side On His New Album
Raekwon The Chef stopped by Shade 45′s Whoolywood Shuffle and talked with DJ Whoo Kid about his highly anticipated Fly International Luxurious Art album. He ...Read More
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On BBC Radio 1 Xtra Live Lounge, Childish Gambino swung by to do a cover of "I'd Die Without You" flexing his singing ability that he ...Read More
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You have to give Jon Stewart credit for honesty: he admits that he loves watching Bill O'Reilly fume at the allegedly pernicious influence wielded by Beyoncé, because "there is very little in this world that I like better than an upset Bill O'Reilly." And really, can't that be said of any of us? A mean old cynic might think that O'Reilly's fixation on Beyoncé — he's done seven reports on her — was merely an excuse to run sexxy video clips "to perhaps provide his elderly viewership with much needed disapproval boners." But Billo's obsession is pure, and very real. He genuinely seems to think that Beyoncé is turning the kids into little sex monsters, as if adolescents have ever been anything but.Related
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December 2014
Our Nation's Myriad Stories
Fascinating tales about this contradictory and compelling country we love.
Tanzania's Mane Attraction
Cameron Ewart-Smith travels to Ruaha National Park, where lions live in great numbers.
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We pick out our favourite gifts to give (and get) this Christmas.
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Snow Monkeys
Ever since the first brave one dipped into a hotspring back in 1964, these wild monkeys have been coming down from the mountains to bathe every single day :)This photo was shot on film. Taken by ihave2pillows with a Canon EOS Series loaded with Kodak Gold 100 (35mm) film in Yudanaka, Japan. These tags describe this photo: monkeys, 湯田中, yudanaka, nagano, hotspring, japanese, macaque, wild, animals, animal, cute, fur, soup, monkey, 温泉, onsen, spa, hot tub, snow monkey, 地獄谷野猿公苑, and jigokudani monkey park. Date: 2013-01-03. Time: Afternoon. This photo can also be found in the album Snow Monkey 地獄谷.
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Jamie Foxx - Fall for Your Type
Artist: Jamie Foxx
Featuring: Drake
Producer: Noah "40" Shebib
Album: Body
Avg Rating: 3.8 ( 90 votes )
Jamie Foxx was riding high after the extraordinary success of his previous album Intuition, but the build-up to his next full-length has repeatedly hit a roadblock that can't simply be blamed on the alcohol; the lack of a hit single (anyone remember Winner?). Never fear Foxx fans, Aubrey Graham is here. For his new (potential) single, Fall for Your Type, Jamie's recruited boy wonder Drake and his trusty production sidekick Noah "40" Shebib, and if history's any indication, America will fall head over heels for this slowly romantic burner. Behind the boards 40 lays down his trademark electro-minimalism, while Foxx once again reminds us that in addition to the acting, he's got some legit vocal chops. And yes folks, Drizzy drops in for a smooth verse that sounds like it could have been picked up off the Thank Me Later cutting room floor. Will Fall provide the push Jamie needs to make Body every bit as successful as Intuition? If so it's going to have to work fast, the album's December 14, release date is getting closer by the second.
Written by Nathan S. on 10/27/10
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First DJ Booth Appearance:
"Please Excuse My Hands ft. Jamie Foxx & The-Dream" (2008)
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@MISC{Rudnicki96anote, author = {Piotr Rudnicki and Andrzej Trybulec}, title = {A Note on "How to Write a Proof"}, year = {1996}}
We believe that mechanical checking of real-life proofs can become practical and therefore we use Mizar -- a proof checking system for proofs written in a style of traditional mathematics. In the beginning of 1994 we came across a copy of L. Lamport's [8] paper in which "a method for writing proofs is proposed that makes it much harder to prove things that are not true." For Mizar users the issue of How to Write a Proof? is an important one, as Mizar is a proof checker and not an automated prover. We have tested Mizar fitness for writing structured proofs in Lamport's style by rewriting his proof of the irrationality of p 2 into Mizar. It was not surprising to notice that formatting conventions help in presenting and reading proofs. However, such conventions do not, as they cannot, guarantee the correctness of the written proof, our little test being a case in point. We advocate development and employment of mechanical checkers for proofs.
Developed at and hosted by The College of Information Sciences and Technology
© 2007-2014 The Pennsylvania State University


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March 2: Lunchbreak - Kale Salad with Balsamic Honey Mustard
Centered Chef
1715 West Chicago Avenue
(312) 226-2433
Chicago Flower and Garden Show
Navy Pier
March 5-13
Centered Chef Cooking Demo
Sunday, March 6
1:30 p.m.
Kale Salad with Balsamic Honey Mustard
Honey Mustard Vinaigrette
6 Tbs honey
6 Tbs balsamic vinegar
1/4 cup Dijon mustard
1/4 cup water
3 Tbs red wine vinegar
1 tsp shallot, minced
1/2 tsp garlic, minced
1 tsp parsley, minced
kosher salt to taste
1 cup barley
4 cups water
1 tsp salt
12 cups kale, stems removed (reserved)
1/4 cup dried cranberries
1/2 cup red onion, cut into thin strips 1/8" wide
1/2 cup goat cheese, crumbled
1 1/2 cups granny smith apple, diced
2 Tbs pecans, toasted and chopped
To make the vinaigrette, add the minced shallots, garlic and parsley to a blender or food processor along with the honey, balsamic vinegar, Dijon, water, vinegar and salt. Blend to incorporate the ingredients and place in refrigerator to chill.
In a sauce pot bring water (second listed amount) up to a boil and add in salt. To cook barley, first spread barley onto a sheet pan, picking out any debris, then rinse thoroughly in a strainer for about 3 minutes. Add barley to boiling water and stir together. Cover the pot with a lid and reduce the heat to low and cook the barley for 35 to 40 minutes.
Soak the kale under cold water for a few minutes to release any debris, then rinse under cold water thoroughly. Dry in a salad spinner or blot with paper towel to remove excess moisture. With a knife, cut along the stems to remove the leaf portions of the kale. Reserve the stems (if desired you may thinly slice these and add back into the dish later).
Thinly slice the kale leaves into ribbons, about 1/8" thick by 3" long. Toss the chilled balsamic honey mustard, cooked barley dried cranberries and red onions with the kale and let rest for 10-15 minutes (the kale to slightly wilt and soften).
Plate the kale mixture and arrange the apples, pecans, and goat cheese.


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Adidas Originals Suisse
—01. Suede and mesh upper.
—02. Collegiate green.
The Suisse is not a style I was ever aware of, but next to a lot of Adidas Originals reissues it stands out as an interesting choice. Pairing more modern elements with a somewhat retro shape, the late '80s style bridges the gap between the well-known classics Adidas offers and some of their contemporary designs.


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It's ski season in Borovets, so book early if you're coming for some fun on the slopes Dec - Mar 2012.
Email me for booking enquires - email@example.com - Dave. It would be great to have you come stay at our ski-slope apartment - right where the action is in the ski resort of Borovets.
Teaching them to fly - I keep a separate aviation blog for my time in the air, but taking on my first students and teaching them to fly is memorable enough to put on my general b...
4 weeks ago


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Special Events
Missing Pages Lecture Series
Now thru March 2015.
Lecturers from history, politics, culture and social sciences
Economic Vestiges of Enslavement
December 4, 2014
Lecturer: Dr. Authens (Asantewaa) Oppong Wadie, DePaul University and Concordia University, Missing Pages Lecture Series
Hidden Colors Film Series
December 7, 2014
Traveling around the country, the film features scholars, historians, and social commentators who have uncovered amazing facts
The 21st Annual Holiday Glitz Benefit Gala
December 14, 2014
The DuSable Women's Board is a group of women who are dedicated to increase memberships, awareness, and support of the museum.
"Understanding The Power of African Centered Perspective"
December 18, 2014
Missing Pages Lecture Series to bring focus to events, activities and achievements throughout history of this country and world.
Discovering DuSable Digitally
FREE Web Exhibition and Learning Resource
Resource allows teachers, parents and students to gain tangible exposure to life and times of Jean Baptiste Pointe DuSable
Lecture by Art Burton, "THE BLACK WEST – Cowboys, Outlaws and Lawmen"
January 15, 2015
Art T. Burton has spent the better part of 20 years reclaiming the heritage of African Americans in the American West.
Join the DuSable Museum on the Soul Train Cruise 2015!
Feb. 22, 2015 thru March 1, 2015
The Soul Train Cruise has become the "homecoming" event for fans of classic R&B music. Special Savings for DuSable Museum Guests


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Salem State University Campus RepresentativeBookmark This
352 Lafayette St
Salem, MA
DescriptionVirtual Internship for Salem State University Campus. Only one Representative per Campus.
Spudder is seeking talented and high-spirited college students to be part of the Spudder College Representative Program.
The position is unique and very exclusive, as there can only be one individual chosen to represent each school. Being a Campus rep will involve working closely with the company to promote connectivity around your college.
What is Spudder?
http://igg.me/at/spudder/x/6081816 will explain more about Spudder while highlighting some of the work that the interns at FDU have done with Spudder. http://info.Spudder.com is an all-encompassing sports management platform. It helps amateur sports teams promote their sport, connect with fans, manage their team rosters, and fundraise. Spudder is one of the first of its kind, and there couldn't be a better time to get on board with the team, as it grows and expands to different areas.
Benefits of the College Rep Program
As the sole representative at your college, you will have the opportunity to practice: marketing; networking; and promotional skills. As part of the team, you will be tasked with a unique project, all the while making meaningful contributions towards Spudder and your career.
Along with the invaluable experience you will receive from working alongside our team, you will also be entitled to compensation. The more successful a college rep is at networking through the school, the higher the rewards.
ResponsibilitiesIntroducing your campus to Spudder. You will simply be making people aware of this new system related to amateur sports. You will have a unique link that use to let users know about the system. If individuals request more information you will earn compensation off the revenue produced from that individual.
It is a simple case of being social and spreading the word and helping us improve are product so that everyone on your campus want it.
-Currently attending Salem State University.
-Connected on Campus: The college rep program is seeking students who are highly social; connected in many groups around their school.


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Bulgaria PM to Participate in European People's Party Summit in Limassol
Bulgarian Prime Minister Boyko Borisov will participate Friday in a European People's Party (EPP) summit in Limassol, Cyprus, according to reports of the press center of center-right ruling party GERB.
The summit's agenda includes topics like the EU's multiannual financial framework for the period 2014-2020 and the preparation for the 2014 European elections.
The hosts of the forum will be EPP President Wilfred Martens and President of the Democratic Rally (DISY) Nicos Anastasiades.
The extraordinary summit will also be attended by European Commission President Jose Manuel Barroso, European Council President Herman Van Rompuy, EPP Secretary-General, Antonio Lopez-Isturiz, and the Presidency of the EPP.
The list of participants in the summit includes European Council members, government representatives, European Commission representatives, opposition members and leaders, and European Parliament representatives.
- » Bulgaria to Get 6% of Requested EUR 300 M under EU Solidarity Fund
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- » EU Commission to Go On with CVM Reports on Bulgaria, Romania


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Christmas Jars Reunion: A Novel
Shadow Mountain, 2009 - Fiction - 200 pages
It's been two years since Hope was reunited with her biological mother on Christmas Eve at Chuck's Chicken n' Biscuits. Hope has never felt more complete. She's writing full-time for a family magazine and, with the help of her mother, Marianne, leading the Christmas Jars Ministry out of Chuck's quirky restaurant. Then her world changes forever when two men unexpectedly enter her life during the holidays.
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This guy is such a good writer. - Goodreads
I don't know why, but I was dissapointed in the ending. - Goodreads
Well written and easy to read. - Goodreads
Great concept, just not the best writing. - Goodreads
Not the concept of the ending, that was wonderful. - Goodreads
Review: Christmas Jars ReunionUser Review - Sara - Goodreads
I liked the first book a little better and since it's been a year since I read it, there were a lot of characters to recall. Christmas jars are filled with spare coins until they are full and then ... Read full review
Review: Christmas Jars ReunionUser Review - Carolyn - Goodreads
This guy is such a good writer. There was one thing in this book that I disagree with though. But its just my own personal opinion. A girl in the book has CHD-congenital heart disease. This means you ... Read full review


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ACE Fit Share
Add some diversity to your fitness program with these butt and hip exercises from the American Council on Exercise. We'll help you tone up those glutes and get that butt into shape. Choose from a wide variety of hip flexibility and strengthening exercises including glute bridges, BOSU lateral jumps and more. These exercises come with detailed instructions, step-by-step guidance and tutorials on proper equipment use. For full workout routines featuring butt and hip exercises, be sure to visit our Workouts section.
Fit Life Articles
Wondering how to keep the kids moving (and burning off some of that enviable energy) when cooler temperatures force them to spend more time indoors? If you find yourself housebound with restless kids, use these great ideas to set up a relay or obstacle course around your...
One of the most common misperceptions about exercise that it is necessary to spend hours busting your butt and sweating buckets to obtain benefits like weight loss, muscle growth and improved overall health and well-being. Here are eight reasons why you should consider...
Asking a young athlete to perform too much, too soon is like sending a bird out of its nest before it has learned to fly. That's why wisely progressing a young athlete's training program is absolutely essential to his or her long-term success. Here's what you need to know...
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"This card is exactly how it is portrayed. The paper quality and print quality are superb. Make sure you order the size card you want, because the default is on the small side. Also, it arrived a day before it was expected. I am pleased with my order!"
"This postcard was so easy to personalize. My daughter was able to place her favorite pictures in the spaces provided, and I was able to post a personal note on the back. We both liked the casual feel of the announcement, and we received many compliments on the card from our recipients. They also appreciated the less than formal feel - most of my daughters friends really hated the formal announcement their school selected for them. And everyone who received one stated their appreciation of the personal note where I listed her academic accomplishments. :-)"
"I love the quality of the card. It was heavy card stock not flimsy photo paper. Great coloring and quality. So far all who received one absolutely loved it. It was nice that I could "customize" the photo with the vintage look. I would order this one again for my next graduate."
"Everything turn out beautiful, the picture , the quality it outstanding , fast and easy to order, i have to reorder more and costumer service is just wonderful to talk too."
"Announcement was perfect. I altered each section to be worded the way I needed- adding words and actually changing what some sections said and covered. I fit everything I needed and wanted on the announcement. Pictures on back were an extra treat , good quality and free! Customer service is great, plenty of communication emails and very fast delivery."