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Tuesday, 26 August 2014
Chrysonilia sitophila
Chrysonilia sitophila -Hyphomycetes (formerly Monilia sitophila)
Chrysonilia species are a cosmopolitan (widespread) saprobe (lives of dead or decaying plant matter). Chrysonilia may be found within the home as 'red bread mould', named for the colour of growth found on contaminated bread. Chrysonilia is the asexual state (anamorph) of Neurospora, its sexual or (teleomorph) state. Neurospora's ascospores are stimulated by applied heat and therefore Neurospora and the Chrysonilia anamorph may be the first organisms to repopulate areas devastated by grass or forest fires. For the same reason, it is notorious for populating heat sterilized soils such as those found in greenhouses. Chrysonilia's teleomorph, Neurospora, is frequently used in the study of genetics and basic eukaryotic cell biology because of its desirable growth characteristics.
Chrysonilia sitophila was formerly called Monilia sitophila; however the genus Monilia now only encompasses plant pathogens.
Chrysonilia is considered to be a contaminant and is not considered to be very pathogenic. It has been implicated in peritonitis, eye infections as well as occupational asthma.
Macroscopic Morphology:
· Colonies exhibit extremely rapid growth, maturing within 72 hours.
· Colonies can range in colour from white to a pale pink, a salmon colour to light orange.
· Texture is very cottony which quickly fills the petrie dish, often referred to as a "lid-lifter" as it crawls up the sides of the dish and presses against the lid.
Chrysonilia sitophila - 24 Hours growth on SAB agar plate incubated at 30˚C (Nikon)
Chrysonilia sitophila - This composite shows how quickly this fungus grows. Within one day the centrally inoculated plate has been filled with the mycelium. By 4 hours it has already completely filled the standard petrie dish and the areal hyphae are pushing against the lid. By day three, the slight pinkish to salmon to light-orange colour, characteristic of this fungus is evident. After a week the growth may have collapsed back on itself and be even be trying to crawl out the sides of the petrie dish. This organism is notorious for contaminating laboratories with the multitude of spores (conidia) produced. (Nikon)
Microscopic Morphology:
· Chrysonilia produces smooth-walled, hyaline, septate hyphae.
Sources differ on their description of the conidia produced. The majority of sources I consulted only mention rectangular 'arthroconida', produced as the hyphae disarticulate or break-up. Yet another source mentions blastoconidia in addition to the arthroconidia. By definition these should emerge as a bud which is then cleaved off at maturity, often leaving a mark or scar at the point of attachment. I have pointed these out where I believe they match the description.
· Simple, poorly differentiated conidiophores can be single or branched.
· Conidiophores produce branching chains of oval conidia (5-10 µm X 10-15 µm)
· Mature hyphae break up forming thick-walled rectangular arthroconidia connected by disjunctors.
Chrysonilia sitophila -a first look at low magnification.
Chrysonilia sitophila -septate hyphae are seen with poorly differentiated conidiophores producing chains of rather round blastoconidia. Rectangular arthroconidia are also evident, produced as the hyphae fragment or disarticulate.
Chrysonilia sitophila - another view as above.
Chrysonilia sitophila -and another. The rather round Blastoconidia (Bc) are being produced in addition to the rectangular Arthroconidia (Ac). Are the so called 'Blastoconidia' referring to immature or developing arthrospores in one source? The blastoconidum shown clearly does not appear to be the product of a fragmenting hyphal element. The hyphae are septate (S), along the lines where they will disarticulate into separate arthroconidia,
Chrysonilia sitophila -Branching hyphae & conidiophores.
Chrysonilia sitophila -ditto
Chrysonilia sitophila -whether these are considered to be blastoconidia or immature arthroconidia, chains are clearly shown to be developing from a branch extending from a main hyphal element.
Chrysonilia sitophila -arthroconidia can be seen joined to each other via a disjunctor cell (Dj) which appears as a small bridge separating one cell from the next. Various texts show the disjunctor as being more pronounced than seen here.
The photograph show above, as several of the previous, are taken from an adhesive tape preparation. I have found at times that an adhesive tape preparation preserves features better than a slide culture and sometimes the opposite. Use whatever technique works best for you. Overall, I like slide cultures as it generally produces a much clearer photograph. In tape preps such as this, you can often detect the unevenness of tape surface and distribution of the adhesive. Here the background is full of bubbles from trapped air and the adhesive.
Chrysonilia sitophila -hyphae disarticulating into arthrospores (AC).
Chrysonilia sitophila -once again, it appears to me that there is a distinct difference between the blastoconidia (BC) which often appear to develop from the side of the hyphae or rudimentary conidiophore and those of the already rather rectangular arthrospores at the apex of a fragmenting hyphal element. (Dj = Disjunctor)
Chrysonilia sitophila - One last photo again showing what I call a round blastoconidium (BC) on a very basic conidiophore (Cp). To my eye, these look distinctly different from the rectangular arthrospores forming by the disarticulation of the hyphae which they originate.
Physiological Tests:
· +Growth at 37˚C.
· +Growth on Cycloheximide Agar
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Posted by Yuri at 15:07 Links to this post
Thursday, 21 August 2014
Trichosporon species
Trichosporon species: (Basidiomycetous yeasts)
This post contains three species from the genus Trichosporon. I chose to deal with these together because of their common elements and that relevant features could be illustrated with a minimal number of photographs for each. Included here will be Trichosporon mucoides, Trichosporon asahii and Trichosporon inkin. I'll add others if and when I come across them in the laboratory.
Generic Description of Trichosporon:
Ecology: Ubiquitous – found in soil and on plant material as well as humans and animals. It may be present as normal flora on the skin, on nails and in the mouth of humans.
Pathogenicity: Five species of Trichosporon are generally considered to be of clinical significance, these being T.mucoides, T.inkin, T.asahii, T.asteroides and T.cutaneum. Recent molecular studies have altered the taxonomy and with it the species names associated with various ailments. The species T.beigelii appears to be obsolete and may have been composed of the species listed above. Localized systemic as well as disseminated infections are increasingly being found in immunocompromised patients such as those with acute leukemia. Most frequently implicated are T.asahii or T.mucoides. Other species may be involved in superficial mycoses. All of these Trichosporon species have been implicated in a superficial, asymptomatic cosmetic condition called white piedra. It is characterized by the presence of relatively soft, white nodules located along the shafts of hair. T asahii is considered most closely linked to white piedra, although some authorities believe T ovoides is the main agent of white piedra of the scalp while T.inkin prefers the groin area and pubic hairs.
Note: Trichosporon species initially appear as yeast cells which develop arthroconidia as they mature. Adhesive tape mounts are of little value and slide cultures fare only slightly better. The method I employed here in observing Trichophyton was to inoculate a Corn Meal Agar (CMA) plate by scratching the yeast into the agar surface and covering it with a cover slip. (The coverslip prevents you from driving your objective into the culture when viewing) After appropriate incubation, the slide holder can be removed from a microscope and the arthroconida observed under low power by placing the open agar plate on the microscope stage and carefully lowering the objective into position.
CAUTION: Make sure you apply a coverslip to the media at the time of inoculation. After appropriate incubation, this allows the culture to be viewed undisturbed. Also, DO NOT use this technique for moulds (filamentous fungi) as the spores will become airborne, enter your nose and cause your head to fall off!!
Microscope with the slide holder removed, incubated plate in place, and objective carefully lowered to view the growth under (and around the edge of) the cover slip. The plate can be carefully moved around by a very steady hand (do this before coffee break!). Objective turret should be raised when placing or removing the plate and when changing objectives. Stick to the lower powers.
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All descriptions below are from Trichosporon species grown at 30˚C on Sabouraud Dextrose Agar (SAB) or Corn Meal Agar (CMA) as indicated. Corn Meal Agar is used as it is less nutritious than the SAB. With a less favorable nutrition source, the organism may be somewhat more stressed and therefore develop spores, be they blasto or arthro, as a mechanism for dissemination and survival.
Some elements in the photos may appear larger or smaller at the same magnification. This is most likely due to my enlarging, then cropping a photo to emphasize a particular feature.
Trichosporon mucoides:
Macroscopic Morphology: On SAB agar at 30˚C colonies appeared yeast-like, moderately expanding with a shiny, moist or mucoid appearance (hence the name). They developed a light cream-like colour.
Trichosporon mucoides, SAB, 8 Days at 30˚C. Note the mucoid texture, hence the name. (Nikon)
Microscopic Morphology: Initially the cells appear as budding yeast cells which expand to produce slightly barrel-shaped arthroconidia. Terminal or lateral blastoconidia are present when mature.
Trichosporon mucoides colony as seen on Corn Meal Agar (CMA) viewed through the microscope as described above. It should be evident that when viewed as described, the cells are unstained. The creamy yeast like forms expand to produce hyphae & pseudo-hyphae (chains of individual cells which mimic hyphae) which grow out from the center of inoculation. (100X, Nikon)
Trichosporon mucoides -edge of the colony growing outwards from the center. The hyphae can be seen to branch. (CMA, 250X, Nikon)
Trichosporon mucoides -a closer look at the hyphae. Branching is evident.
(CMA, 250X, Nikon)
Trichosporon mucoides -hyphae can be seen developing into individual arthrospores along with blastospores along the sides. (CMA, 250X, Nikon)
Trichosporon mucoides -as above (CMA, 250X, Nikon)
Trichosporon mucoides -ditto. (CMA, 250X, Nikon)
Trichosporon mucoides -Chains of arthroconidia (AC) have developed from the hyphae. Lateral blastoconidia (BC) are present, as the name implies, on the sides of the arthconidial chains or hyphae. (CMA, 250X, Nikon)
Note: See also differentiation table at the end of this post.
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Trichosporon asahii:
Macroscopic Morphology: White to light cream coloured colonies which develop a farinose covering (covered with a whitish, mealy dust) and has a fissured marginal zone.
Trichosporon asahii - SAB, 72 hours at 30˚C. Culture almost looks mixed with lighter and darker colonies. Colonies appear quite dry in contrast to the Trichosporon mucoides described above.
Trichosporon asahii - SAB, 30˚C, one week. Again, note the dry wrinkled apperance. The white mealy growth in the heaviest area (Lower right quadrant) is the farinose texture described in the text above. (Nikon)
Different techniques can be used to view all the Trichosporon species. Here I used both the plate method viewed on a microscope withe the slide holder removes, and the adhesive tape technique. Try whatever technique best captures the features that describe the species.
Microscopic Morphology: Again, initial culture appears as yeast cells which grow to develop barrel-shaped arthroconidia. Budding cells and lateral conidia are absent.
Trichosporon asahii - Initial growth on the CMA plate as viewed through the microscope set-up described above. Fine hyphae can be seen extending out comprising the colony.
(CMA, 100X, Nikon)
Trichosporon asahii -as above but photo taken at edge of the outgrowth.
Trichosporon asahii -Taking a step back, these are the T. asahii yeast cells as they appear taken from the SAB colony plate. It is this form that makes Trichosporon a yeast-like fungus. Trichosporon grows as a yeast, both at room temperature and at 37˚C (not to be confused with a true dimorphic fungus). These yeast grow out forming hyphae or pseudohyphae, fragmenting into arthrospores.
Trichosporon asahii -edge of a colony as viewed using the adhesive tape method. Not the best method to use because of the yeast-like texture of the colony. Free cells are seen to the left with the edge of the colony to the right.
Trichosporon asahii -the edge of the colony is to the left in this photo. Extending out from the colony are hyphae and chains of arthroconidia (near top of photo)
Trichosporon asahii -with a closer view, the difference between the smooth-walled hyphae and the chains of arthroconidia is evident. Here they lie side by side. In the upper right of the photo, the transition of the hyphae as it fragments into arthroconidia is quite evident.
Trichosporon asahii -another view, as above.
Trichosporon asahii -as above. Regardless of the technique used to observe the fungus, note that there are no lateral blastoconida on T.asahii that we saw on the T.mucoides isolate.
Trichosporon asahii - Barrel-shaped arthroconidia, but no lateral blastoconidia.
Trichosporon asahii -a hyphal element running from right to left through the center of the photo can be seen disarticulating (fragmenting) into barrel-shaped arthroconidia.(1000X, LPCB, DMD-108)
Note: See also differentiation table at the end of this post.
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Trichosporon inkin:
Macroscopic Morphology: Colonies are initially yeast-like, off-white to cream coloured, smooth, moist and soft in texture. As the colonies mature they become finely cerebriform (wrinkled), farinose (covered with a whitish, mealy powder) or crumb-like. The center of the colony may become heaped up and the aging colony may adhere to and even crack the agar.
Trichosporon inkin -SAB, 30˚C, 72 hours. Off-white, soft cream-like texture
Microscopic Morphology: Initially the cells are yeast-like however on incubation true hyphae as well as pseudohyphae develop. Long, cylindrical arthroconidia (2 – 4 µm X 3 – 9 µm) develop as the colony matures. Blastoconidia may form singly or in short chains, however lateral conidia are absent. Appressoria (a speciallized cell which assists the fungus in infection) may be present and best visualized in slide cultures.
Trichosporon inkin -rather than using the LPCB stain as with the T.asahii (above), here you can see the yeast cells as they appear suspended in ~10% Potassium Hydroxide solution (KOH).
(I have this noted as 400X, KOH, Nikon, but the magnification may be higher -ooops!)
Trichosporon inkin -as with the other Trichosporon species presented above, this is the T.inkin colony producing hyphae and pseudo-hyphae which extend from the point of inoculation.
(CMA, 100X, Nikon)
Trichosporon inkin -a blastoconidium can be seen developing at the end of a hyphae (upper right). Lateral blastoconidia, as seen with T.mucoides, are not produced.
(CMA, 250X, Nikon)
Trichosporon inkin -blastoconida at the apex of the hyphae.
Trichosporon inkin -disarticulation (fragmentation) of the hyphae into arthroconida is seen here.
(CMA, 250X, Nikon)
Trichosporon inkin -branching hyphae & pseudo-hyphae fragmenting into arthroconidia.
(CMA, 250X, Nikon)
Trichosporon inkin -another view as described above.
Trichosporon inkin - and yet another (ditto)
(CMA, 250X, Nikon)
Below is a table of physiological features which will help distinguish between the species presented here.
Differentiation: Trichosporon differs from Cryptococcus species in that it produces arthroconidia while Cryptococcus does not. Trichosporon can be differentiated from Geotrichum in that Geotrichum does not produce blastoconidia and is urea negative.
Inoculation onto Malt Extract Broth at room temperature encourages the production of blastoconidia in Trichosporon species. Corn meal agar may do the same.
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Thursday, 3 July 2014
Scopulariopsis brumptii
Scopulariopsis brumptii (Mould/Fungus)
Ecology: A cosmopolitan fungus (found just about everywhere), particularly in soil and in household dust.
Pathogenicity: Scopulariopsis brumptii is rarely implicated in disease; however, as with many other 'non-pathogenic' fungi, they may be considered opportunists and may be increasingly found as the cause of pulmonary (lung) infections in severely immunocompromised patients. Encountered in the laboratory as a possible contaminant, they must be distinguished from more pathogenic fungi.
Macroscopic Morphology: S.brumptii is a moderately rapid grower, usually maturing within about 5 days. Surface growth may initially be whitish, then darkening from a light grey to a sepia-grey (reddish overtones) or fuscous (darker brown-grey). One source described the colour as that of cigarette ash. The grey overtones distinguish it from the cinnamon, tan or buff brown colour of Scopulariopsis brevicaulis. The texture is described as velvety to powdery.
Scopulariopsis brumptii - Sabouraud-Dextrose Agar
(SAB, 12 Days, 30oC, Nikon)
Microscopic Morphology: S.brumptii produces septate hyphae that are hyaline when young but darkens as it matures. Conidiogenous (conidia producing) cells develop from the hyphae and can appear singly or in brush-like arrangements. These conidiogenous cells are more specifically referred to as annellides as they produce conidia (annelloconidia) in succession, each leaving a ring-like collar on the annellide when the annelloconidia is released. The annellides (5 µm – 10 µm X 2.5 µm to 3.5 µm) are somewhat flask-shaped, with a swollen base which tapers near the apex, however they are generally more cylindrical that those of S.brevicaulis. The annelloconidia (4.0 µm – 5.25 µm X 3.5 µm – 4.5 µm) in size and although they can be smooth, the texture is usually described as finely roughened. They are usually pyriform (pear-shaped), dark brown in colour and have a flattened or truncated base where once attached to the annellide. The annellations (scar/ring) produced by S.brumptii may not be very conspicuous. Annelloconidia are produced in loose chains from the apices of the annellides.
Scopulariopsis brumptii - darkly pigmented annelloconidia.
(KOH, 400X, Nikon)
Scopulariopsis brumptii -hyaline hyphae become pigmented as are the ellipsoidal annelloconidia.
(KOH, 1000X, Nikon)
Scopulariopsis brumptii - conidiogenous cells develop from the hyphae either singly or in brush-like arrangements. These annellides produce the oval or ellipsoidal, darkly pigmented annelloconidia.
Scopulariopsis brumptii - an annellide is seen in the center of the photo extending from the hyphae. The "three-fingered" brush-like arrangement at the apex has anelloconidia still attached and some which have been released. (KOH, 1000+10X, DMD-108)
Scopulariopsis brumptii- appear to be two single annellides, with annelloconidia being produced at the apex. (KOH, 1000X, Nikon)
Scopulariopsis brumptii -the hyphae is septate and has produced a single annellide, bearing a single annelloconidium, at the center of the photo. (KOH, 1000X, Nikon)
Scopulariopsis brumptii -two brush-like arrangements of the annellides of S.brumptii are seen here in the center-left of the photo. Numerous annelloconidia, both attached and free are seen.
Scopulariopsis brumptii - two bunches of annellides (the right one more brush-like than the left) are seen in the center of the photo. Pigmented annelloconidia are seen at the apex.
Scopulariopsis brumptii -More brush-like annellides showing their arrangement and attatchment of annelloconidia. (LPCB, 1000X, DMD-108)
Scopulariopsis brumptii - another branching annellide, thinned out a bit so the arrangement of the annellides are more easily seen. The ring or collar is clearly visible on the annelloconidium seen at the lower middle of the photo. It appears as a scar or flattened base where the annelloconidium was once attached to the annellide. (LPCB, 1000X, Nikon)
Scopulariopsis brumptii -okay, too many photos, but what else am I going to do with them?
Hyphae, annellide & annelloconidia extending from the tips.
Scopulariopsis brumptii -ditto. Lots of annelloconidia produced by this brush-like structure.
Scopulariopsis brumptii -two single annellides seen extending from the hyphae traversing the center of the photo. Each has an annelloconidium still attached to the apex. Look closely at the darkly pigmented mature annelloconidia and you will see the collarette (annellide ring) on many.
Scopulariopsis brumptii -a poorer example of the photo explanation above. Two single annellides producing annelloconidia. Many more single annellides are present in S.brumptii cultures than in S.brevicaulis cultures where the arrangements are primarily brush-like.
Scopulariopsis brumptii -again, as above, single, rather than brush-like arrangements might be seen more frequently in S.brumptii, than in S.brevicaulis.
Scopulariopsis brumptii -ditto - more single, rather than brush-like annellides may be seen in S.brumptii cultures. (LPCB, 1000X, DMD-108)
Scopulariopsis brumptii -and a single annellide with an attached annelloconidium seen in the center of the photo. A single free annelloconidium is seen in the upper left-third of the photo - the annellide ring or collarette visible at the bottom. (LPCB, 1000+10X, DMD-108)
Scopulariopsis brumptii - a crowded photo showing at least two brush-like arrangements of annellides within a 'sea' of pigmented annelloconidia.
Scopulariopsis brumptii -oh, what the heck! -here's one more. A brush-like arrangement of annellides and darkly pigmented, oval to ellipsoidal annelloconidia.
Note: Scopulariopsis species may show variable sensitivity to cycloheximide and therefore may or may not grow on Mycosel/Dermasil® agar.
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Posted by Yuri at 22:37 No comments: Links to this post
Labels: annellides, annelloconidia, KOH, Scopulariopsis brumptii
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What marriage conserves
Damon Linker has an interesting article at The Week in which he makes the case that the Culture Wars are really all about sex, and while he identifies himself as in tune
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Running time 11:00


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Playing for the Cause Helps Out Those in Need
By Joseph Hess
Those who frequent Lemmons — for its popular trivia nights, its weekend shows and, of course, the delicious pizza — know Jamie Foehner, the power-pop-lovin' doorman/booking agent. Due to some recent health problems and an extended hospital stay, Foehner needs some help with his medical bills. Thankfully, Lemmons is stepping up to help its beloved employee with a daylong benefit on his behalf. Along with games, raffles and (of course) trivia, this event will feature musical entertainment provided by the Trip Daddys, Bunnygrunt and Bad Folk. The entire shindig will be emceed by improv comedian Bill Chott — which is fitting, as Foehner trained at Chicago's Second City comedy school (alongside Stephen Colbert and Steve Carell!).


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I'm sorry that I've been away from my blog for a long time. I've had a series of computer issues and trips. But hopefully I'll be back to blogging regularly again. I'll start with this post, which I started back in April before the computer glitches.
One of the things I have been enjoying this year is not having many deadlines associated with my quilting. Yes, I have a few - the Block of the Month is due at each meeting and the guild challenge quilt is due in June. But mostly I've been able to work on projects at my own time and speed.
One project which had a bit of a deadline is my nephew's high school graduation quilt. I came up with the idea of collecting fabric which reflects his interests at this time of his life a couple of years ago. Fabric for this quilt is most of the fabric I have bought since I began recording how much of my stash I have been using.
I got the last bits for this quilt at the World Quilt Show Florida in January. I looked at the pile of fabrics, all in different colors on different backgrounds and had no idea how I was going to pull it all together. Then I saw this pattern on Craftsy. I found a neutral grey fabric in my stash and, suddenly, it all worked.
The pieces are large enough to show the fabric and the neutral grey in between pulls it all together.
I'm pleased to say that when I delivered the quilt in May, my nephew was quite pleased with it. You never know with guys. He sent me the most lovely thank you note which clearly showed me that he understood what I was trying to do with this quilt. "It's a memory quilt," he said. So right he is.


text: No recent wiki edits to this page. When Gotham City Challenged Metropolis(Superman, Batman and Robin / written by Edmond Hamilton) -- 2. The Mechanical Archer (Green Arrow) -- 3. The Schooner on Wheels (Tomahawk) "Featuring your two favorite heroes together in one adventure..."Someone in the crowd: Batman and Robin win another point for that stunt-- but Superman is getting one, too, for rescuing them! "Score of exploits"


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Gulf Shores Condo Rental Photos and Description
Condo, 2 King Bedrooms + Bunk room, 2 Baths, (Sleeps 6-8)
The Lighthouse sits directly on the Gulf of Mexico less then 1/2 mile down East Beach Blvd. (Hwy. 182).
Please note: We have another 3 bedroom with 3 bath unit on the 3rd floor (just doors away) at The Lighthouse and the vrbo # for it is 289529. We also own a 4th floor 3 bedroom/3 bath unit at the San Carlos condominium complex. The VRBO # on that unit is 227150.
If you enjoy lounging by the pool, prepare yourself as there are three! The first is a extremely kid-friendly zero entry pool which starts at about 2 inches in depth and gradually extends to five feet deep. The children will be thrilled to splash, play and run under the water jets. The second pool is suitable for everyone else and both are huge.
Can't you just feel yourself relaxing under the palm trees in one of the many chaise lounges surrounding both pools? Are hot tubs your favorite way to unwind? There is one located at each end of the pool along with chairs for chatting with friends. The remaining pool is a very large heated indoor pool. This pool,the fitness room and cedar sauna are on the first floor with a perfect beach view from the walls of windows.
The four high speed elevators are enclosed in individual rooms which buffer any noise to the nearby condos. Your room is conveniently located just feet away from one which accesses all of the 1st floor amenities!
Your condo has been tastefully and comfortably decorated. The master bedroom has a king size pillow top mattress. It has a 19' flat panel TV w/DVD player and a ceiling fan. There is ample storage in the walk-in closet with plenty of shelving and hangers. The master bath has a separate double vanity dressing area before you walk into the main bath area with the whirlpool tub, glassed-in shower and commode. The master bedroom and living room both have heavy drapes with blackout lining.
The guest bedroom also has a king pillow-top mattress and ample closet storage with shelving and hangers. It also has a 19' flat panel TV with DVD and a ceiling fan. The guest bath is a shower/tub combination and can be accessed through the guest bedroom and the hallway both. Both bathrooms have hairdryers for your convenience. The bunk room contains two twin beds and is cheerfully decorated.
The living room has a large flat panel TV with DVD player and a ceiling fan. The couch converts to a sleeper sofa and your have super soft linens here too. The kitchen is very well equipped with all of the major and small appliances you will need including a large coffee maker and heavy duty blender, it also has a huge separate pantry. We also have a high chair for the little ones. All of the rooms have new earthtone colored tile with the exception of the 2 main bedrooms which are carpeted.
The beautiful white sand and turquoise water is like no other. The view from your balcony is simply breath taking. It is accessible from both the living room and master bedroom and is a very spacious.You can watch the kids enjoy the pool, carry on a relaxing conversation and still hear the waves crash on the beach- the best of all worlds! The view is magnificent- enjoy the peaceful mornings watching for dolphins to jump or soak in the breezy evening sunsets.
We normally try to have only Saturday to Saturday rentals during the peak season, however, there are some partial weeks availible.
On a personal note- We have enjoyed the Gulf Shores area for several years now and it is our hands-down favorite. We picked the condo we own because we feel it represents the best of all worlds- a very child-friendly atmosphere but also well-appointed for our adult guests.
It is close to everything you want and need in the way of dining and shopping. The rooms have been outfitted to make it your home away from home and your comfort and fun is foremost in mind. Don't wait another minute and book your vacation with us today!
Keywords: Condominium, gulf front, gulf, beach front, beach
- Suitability:
- Long-term Renters Welcome
- Minimum Age Limit for Renters
- children welcome
- limited accessibility
- non smoking only
- pets not allowed
- suitable for elderly or infirm
About The Owner
We live in Kentucky and have always really enjoyed our vacations in Gulf Shores. We decided to buy our first condo in late 2008 and due to a SEVERE ice storm in January 2009, escaped their for a few days. We ended up purchasing our other condo at an auction while we were there. I told my husband it was fate that we were there at that time and it was meant to happen ! So, this is our first year renting and we have been thrilled we the results so far. All of our clients have been great to work with and everyone comments on how they have enjoyed their stay with several mentioning they will be back again for certain. This is exactly what we had intended when we decided to begin our rental business. We want to develop loyal customers because they know what we will provide to them and how we value their business.
I ask each client if they have been to the area and if they haven't ( or it's been a few years), I try to provide them with info of the area and activities. Even though the beaches are beautiful,there is just so much to see and do in the entire gulf coast area.
Our family has been involved in a construction related business for 29 years and customer service is truly our number one priority. Clients are spending their hard earned money to relax and get away from it all for just a few days. We want to exceed their expectations on what a vacation rental home should be.


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StartUpHire is the place to find Senior Quality Assurance Development Engineer jobs. Review the list of Senior Quality Assurance Development Engineer career opportunities to the left. These Senior Quality Assurance Development Engineer jobs represent some of the most rewarding careers available.
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Location: Waltham, MA, USA Job Title: Senior QA Engineer Department: Global Support Description: MetraTech empowers organizations to embrace change through a unique, agreements-based billing and compensation solution that is relationship-driven and supports fluid,9/28/2014 Waltham, MA Save This Job
You know LivingSocial as the marketplace to buy and share the best things to do in your city and beyond. And while we're bringing excitement and value to our merchants and consumers, we're also committed to creating a world-class environment for our employees. Our talented11/21/2014 Washington, DC Save This Job
Vector Software, the leading provider of automated software testing solutions, currently has an opening for a Senior Quality Assurance Engineer. In this role, you will be responsible for working as part of our QA team to perform validation of new functionality with free play9/30/2014 East Greenwich, RI Save This Job
Job ID 2014-2713 Job Location US-TX-Austin Category Engineering Type Full-Time More information about this job: About Bazaarvoice: Bazaarvoice is based on a simple truth; when people talk to each other, people buy stuff they are happy about because they trust the opinions of10/28/2014 Austin, TX Save This Job
Are you looking for an opportunity to accelerate your career and work with a team of friendly, creative people? Upland Software offers a collaborative work environment full of smart, positive, and passionate people who are respected for their unique talents and empowered to do10/8/2014 Cambridge, MA Save This Job
Click Here to Complete Your Application Zoom Information is looking for a results-driven, highly-technical Senior Quality Automation Engineer who is passionate about leading edge technologies such as Hadoop, Solr, Cassandra, and JQMS to join our team of outstanding professionals10/5/2014 Waltham, MA Save This Job
Job Description: Work closely with other quality engineers, development and support groups. Architect and design automated functional, compatibility, regression and stress testing of JVM and other pieces of system software. Improve test coverage of the most sensitive product10/28/2014 Sunnyvale, CA Save This Job
Reports To: Director of Regulatory Affairs and Quality Assurance Job Summary: The Senior Quality Engineer will establish and maintain quality engineering methodologies, systems and practices which meet ZONARE, customer and regulatory requirements. The Senior QE serves as a10/21/2014 Mountain View, CA Save This Job
Overview: The Senior Software Engineer is experienced in enterprise level Microsoft .NET development technologies and processes that develop internal and external facing applications. Responsibilities: As a member of the team, you will be responsible for architecting, designing10/25/2014 Austin, TX Save This Job
GSN Games?s games are played tens of millions of times each day making it one of the most popular casual gaming companies in the US. In order to keep pushing the limits, we are looking for a talented Senior Quality Assurance Engineer to join our GSN.com Web Applications team.11/16/2014 Boston, MA Save This Job
Socialware is seeking an automation-focused Senior Quality Assurance Engineer to join our team. Quality-obsessed engineers who will bring new automation capabilities to bear are highly sought for this role. Qualified candidates should consider themselves both smart and humble10/6/2014 Austin, TX Save This Job
POSITION SUMMARY: This Senior Software Quality Assurance Engineer will initially be relied upon as the significant QA engineer assigned to a small project team, but may later have opportunities a very hands-on QA leader of 1 to 2 person testing teams, for assigned projects10/26/2014 Boston, MA Save This Job
SENIOR SOFTWARE ENGINEER/SOFTWARE ENGINEER - EMBEDDED SYSTEMS (VXWORKS, C++, WINDOWS) Job Description ViewRay is seeking a senior software engineer or software engineer to deliver product enhancements and develop its embedded control systems and tools for the ViewRay System, a10/13/2014 Mountain View, CA Save This Job
Senior QA Engineer The Senior QA Engineer is responsible for creating and maintaining test plans and test cases, executing formal test plans, and implementing API based regression and performance tests. This position reports to the QA Manager. The ideal candidate has several10/13/2014 Burlington, MA Save This Job
Tracking Code 1605 Job Description Lumension is seeking a Sr. Software Engineer to join our OEM Engineering team. This team member will be working on architecture, design and coding for Lumension OEM partner products which include a number of cross platform Patch Management10/21/2014 Scottsdale, AZ Save This Job
You will work with a variety of technologies including Java,SQL Server, CPLEX, Matlab,Tableau. The idea candidate should possess great organization and communication skills, enjoy taking ownership of key features, and possess a love of problem solving.11/3/2014 Austin, TX Save This Job
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SUMMARY Welocalize, Inc., founded in 1997, offers innovative translation and localization solutions helping global brands to grow and reach audiences around the world in more than 125 languages. Our solutions include global localization management, translation, supply chain10/20/2014 Portland, OR Save This Job
Job Details The Senior Software Engineer will collaborate with Marketing, DSP Algorithms, Hardware, Digital VLSI, Analog VLSI, and Quality Assurance groups to specify, review, test, and troubleshoot System-On-Chip hardware and software integrated into mobile devices. Develop10/13/2014 Mountain View, CA Save This Job


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First Post..
Have any of you had any experiences eating at "The Counter" burger restaurant? They have locations in Irvine, CA - Palo Alto, CA - San Jose, CA - Santa Monica, CA - and Royal Palm Beach, FL.
On the menu, they have a "Burger in a Bowl" option that looks like it might be gluten-free if I order it plain. But I'd rest easier if I heard from people who have eaten there. Has anyone had any experiences with this burger diner?
Thank You
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In Disney Food News this week, a round up of tasty treats! New Frozen-themed Gingerbread Display at the Contemporary Resort! Disneyland Candy Cane Dates! And lots more!!
Posts Tagged 'holidays around the World'
News! Festive Treats Returning to Epcot's Holidays Around the World
Epcot will be celebrating the Holidays Around the World from November 28 – December 30. Join us for a glimpse of some of the special treats to be found around World Showcase throughout the season!
News! 2014 Epcot Food and Wine Festival Cookbook Will Combine All Three Epcot Festivals
We have news today about this year's Festival Cookbook that will be released in time for the 2014 Epcot Food and Wine Festival at Walt Disney World!
Epcot Debuts Sweet and Savory Waffles for the Holidays!
Sweet and Savory Waffles come to Epcot's Promenade Refreshments in Disney World just in time for the holidays!
Holiday Eats! Epcot Celebrates Holidays Around The World
Grab your Passport and experience all the flavors of Epcot's Holidays Around the World!


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OAKLAND, Calif. (AP) -- All-Star third baseman Josh Donaldson is the latest Oakland star traded away in a rebuilding effort.JANIE McCAULEY (AP Baseball Writer)
KANSAS CITY, Mo. (AP) -- Former first-round draft pick Aaron Crow was traded from the Kansas City Royals to the Miami Marlins for left-hander Brian Flynn and right-hander Reid Redman.
SANTO DOMINGO, Dominican Republic (AP) -- Chicago Cubs pitcher Pedro Strop was involved in a car crash in his native Dominican Republic but was not injured, officials said Friday.
Cuban outfielder Yasmany Tomas is in the process of agreeing to a $68.5 million, six-year contract with the Arizona Diamondbacks, according to a person familiar with the negotiations.RONALD BLUM (AP Sports Writer)
NEW YORK (AP) -- Major League Baseball's minimum salary is rising to $507,500 next year from $500,000.


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last weekend I went to a dog sleedind event what do you think of this sport? this was my first time and I noticed that all the dogs seemed to be really excited to participate in the action!do you think they really like doin it?they also had snow sculpting and the artist there were incrediable (. a must see:)
Feb 12, 2010
Oh yes!!!!!!!!! Northern breeds such as huskeys, Samoyeds, and malamutes, love to run and pull! I used to have a Sammy pup and she loved to run. It's a lot of fun for the dogs and I will have to see that one day!
Thumbs Up: 0 | Thumbs up!
Feb 12, 2010
I think they love pulling the sleds! =)
Its like a fun job and what dog doesnt love running and having fun.
Thumbs Up: 0 | Thumbs up!
Feb 12, 2010
i think as long as the dogs enjoy what they are doing it is great. i bet you had a lot of fun.
Thumbs Up: 0 | Thumbs up!
Got a question about your pet? Get the answers you need from Zootoo's community of pet experts and owners.
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There are always new questions that need answers. Contribute your knowledge about pets.
S.O.S.! | Behavior & Training
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Greg Rucka Launches Webcomic: 'Lady Sabre and the Pirates of the Ineffable Aether'
Given how easy it is to post pictures on the Internet -- even pictures that aren't of adorable cats --- new webcomics are cropping up all the time. A new webcomic produced by two established, incredibly talented comics creators, however? That doesn't happen every day.
But it did t


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Capital instruments from third-country insurers must fit Solvency II
Backlog means UK funds are temporarily unable to market in Europe
Industry body says 15-40 trades per day should be rough benchmark of liquidity for Mifid
The Certificate in Quantitative Finance is a global quant program that focuses on teaching practical quant techniques used in risk management.
Join us online to learn more: 11 December
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Yates leaves Citi to become CEO of Two Sigma Securities in September
UK fund managers almost always outperform benchmarks, S&P
Reverse repo treatment in draft NSFR cuts ratio from 113% to 98%
Bank pays fine for mortgage fraud in the lead-up to the financial crisis
Physical deals with producers seen as 'superior' to financial hedging
PRA and FCA unveil new rules on bank bonuses and approval process
US regulator resigns to head derivatives industry group
Firms in Poland and Ireland cannot be fined for breaking reporting rules
Smalls firms baulk at paying up to $18,000 to register a few trades
Banks say they will not hit revenue targets if Esma deadline is endorsed
ETF marks first stage in moves to create domestic derivatives market
NYDFS proposes bitcoin regulations that experts say go too far
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3 to 6 days
Free deliver when you spend over £10 (GBP).
Will be calculated at checkout
You must select a size
Knitted cardigan by SISTERS POINT. Open style with long sleeves.
Made of 48% Cotton, 34% Polyester, 9% Viscose and 9% Acrylic.
Sisters Point is a Danish company creating trendsetting and energetic fashion for young women. Sisters Point offer everything from bodycon dresses to classy playsuits to stressed denim jeans. Nelly.com is proud to offer Sisters Point.
Free delivery when you spend over £10. Delivery time: 3-6 days. We deliver with UPS.
No reviews have been written yet.


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17 results for "generation y"
Reilly: Mizzou students display true spirit supporting Michael Sa...Rick Reilly
Students at Missouri protected Michael Sam from seeing a church's anti-gay protests and showed that more people than you think know how to stand up to intolerance, Rick Reilly writes.Story | Conversation | February 16, 2014
Video results for "generation y"
OTL: Generational DivideJanuary 03, 2013
- 09:22
OTL: Old-school coach vs. Generation YPlaybook Trending
On Sunday's "Outside the Lines" at 10 a.m. on ESPN2, reporter John Barr examines what happens when Generation Y - the generation that came of age at the dawn of a new millennium - encounters the immovable object known as the old-school coach....Blog | January 04, 2013
'Gen Y' players move through college, professional ranksGabrielle Paese
The Cubans call them Generation Y. Children born in the late 1970s and '80s whose parents creatively used the 25th letter of the alphabet for inspiration. Many of them grew up to be athletes. Case in point: First names on Cuba's preliminary roster fo...Blog | Conversation | May 19, 2010
Harvard reaches 20 wins, tops Cornell 67-44
Harvard reaches 20 wins, tops Cornell 67-44Recap | Box Score | Conversation | February 15, 2014
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Planet Media Cinemas Westgate
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- Kill Dil
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- Planes: Fire & Rescue
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- Teenage Mutant Ninja Turtles
- The 7th Dwarf
- The Equalizer
- The Good Lie
- The Hobbit: The Battle of the Five Armies
- The Hunger Games: Mockingjay - Part 1
- The November Man
- Ungli
2 Guns (2013, USA)
A DEA agent and a naval intelligence officer find themselves on the run after a botched attempt to infiltrate a drug cartel.
After Earth (2013, USA)
A crash landing leaves Kitai Raige and his father Cypher stranded on Earth, 1,000 years after events forced humanity's escape. With Cypher injured, Kitai must embark on a perilous journey to signal for help.
Aurangzeb (1993, India)
Gurgaon 2013. A family of policemen and a family of gangsters. To bring down a criminal, the law will have to think like a criminal.
Beautiful Creatures (2013, USA)
Ethan longs to escape his small Southern town. He meets a mysterious new girl, Lena. Together, they uncover dark secrets about their respective families, their history and their town.
Bhaag Milkha Bhaag (2013, India)
The true story of the "Flying Sikh" - world champion runner and Olympian Milkha Singh.
Bullet to the Head (2012, USA)
After watching their respective partners die, a New Orleans hitman and a Washington D.C. detective form an alliance in order to bring down their common enemy.
Chashme Baddoor (2013)
The movie follows Sid (Ali Zafar), Jai (Siddharth Narayan), and Omi (Divyendu Sharma), three friends living in Goa, India.
Chennai Express (2013)
Rahul embarks on a journey to a small town in Tamil Nadu to fulfill the last wish of his grandfather:...
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The film is a high-octane, action-packed thriller starring Vidyut Jammwal who plays a special-ops secret agent for the Indian Armed Services.
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With the help of his mentor, a slave-turned-bounty hunter sets out to rescue his wife from a brutal Mississippi plantation owner.
Elysium (2013, USA)
Set in the year 2154, where the very wealthy live on a man-made space station while the rest of the population resides on a ruined Earth, a man takes on a mission that could bring equality to the polarized worlds.
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A chronicle of the LAPD's fight to keep East Coast Mafia types out of Los Angeles in the 1940s and 50s.
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Jolly LLB (2013, India)
The film is a social satire on the law system of the country India. The story follows a struggling lawyer named Jolly (Arshad Warsi) who wants to make it big in life like his idol (Boman Irani).


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- Forum >
- Electrical & Lighting >
- 18-guage wire
18-guage wire
If you buy a table lamp and plug it into a wall receptacle, which will be wired with at least a 14 AWG wire on a 15-amp breaker, do you think that cord on the lamp is also 14 AWG?
It's not. It'll be 16 or 18 AWG, same as most cheap extension cords and the wires that come with most other light fixtures.
Also, do you think the manufacturer of your recessed light, which is most certainly UL listed, didn't know what it was doing when it built the thing?
I think you can rest assured that if you wire the light according to the directions that probably came with it, you'll have a very safe installation.
This little episode makes me think about those little screw-in adaptors that convert a light socket into an outlet that you can plug something in to. I use one of those on occasion to run my electric lawnmore. I think I'm going to go throw it out now.
I doubt if the inspector would shoot you, but when he recovered from convulsions of laughter he might ask you if you got some kind of irresistable deal on the price of 18 AWG wire.
Besides that, even if you did run the 18 AWG all the way back to the panel I don't know what you'd connect it to. The lightest breaker made for an electrical load center is 15 amp -- probably the same as the one you'll be hooked to in the ceiling installation.
There's obviously a justification for lighting fixtures to be wired with these lighter wires but I don't know what it is. When you think about it, that light won't likely draw even a full amp, depending on its wattage. A 100-watt bulb, for example, would draw 0.833 of an amp.
As for whether you should throw away your screw-in light socket adapter (I've used 'em many times), you might first determine how many amps your mower is drawing.
There should be a plate somewhere on it that tells you the wattage, amperage, horsepower or somesuch about the motor.
If you know the watts or amperage you can get one or the other with a little math:
Watts divided by 120 = amps
Amps times 120 = watts
One horsepower = 746 watts
I checked one of those adapters, made by Leviton, I keep in my toolbox and it says its good for 660 watts max. That translates into 5.5 amps.
So if your mower draws anywhere near that you should retire the adapter for lighter uses.
Actually, if you need an extension cord to reach the whole yard you should probably be running that mower off no less than a 12 AWG cord, if for no other reason than to cut down on voltage drop.
P.S. Aw, go ahead and dig into the wallet, head for a home improvement center and shell out about $40 for a good 100-foot 12/2 AWG w/ground, contractor-grade extension cord. It would be a good investment. Take care of it and you can use it the rest of your life.
And don't run over it with the lawn mower as I did the attached equipment cord on my aunt's brand new electric mower she was so proud of back in the 50s.
[This message has been edited by HBB (edited November 04, 2002).]
But rather than buy a new extension cord, I'm going to buy a new mower, a gasoline model this time. I bought my electric as an experiment back when I had a small, wide-open lawn. I just wanted to see whether I'd like an electric more than a gas model. And I did, for a time. The electric mower is much quieter than any gas model I've owned. However, I've since moved to a house with a somewhat larger yard with lots of trees and other obstructions, and it takes a good deal of forethought not to get all tangled up in the cord as I mow.
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text:
Kenny Howell
Managing Editor
Fellow commissioners and citizens paid tribute to Commissioner Ted Floyd at the meeting Monday. Floyd chose not to seek reelection for the District 1 seat, and Monday was his last meeting.
The new fire station is still several months away from being built, but the existing station looks brand new thanks to some generous citizens.
The Mt. Juliet Animal Shelter Volunteer Organization was awarded a $1,000 grant from the Allstate Foundation Monday.
The grant was a part of Allstate's "Agency Hands in the Community Program."
Elzie D. Patton Elementary will be hosting its annual community celebration of fine arts and business Saturday, Nov. 3 from 9 a.m. to 3 p.m.
The Elzie Patton Expo will be an indoor event that will provide their students the opportunity to take on a leadership role and meet current community leaders first hand.
The 13th Annual Mt. Juliet Homecoming and Music Fest will be held Oct. 27 at 563 Main St. behind Cloyd's Presbyterian Church on West Division.
Old Time, Country, Bluegrass and Gospel Music will be featured all day from 9 a.m. til 5 p.m.
Remember Me


text:
Other clinical trials
Not yet recruiting
Phase 1
One Week Comparison Study of PTH and PTHrP Infusions
January 2015 - July 2017Study type: Interventional
This is a dose escalation study to determine the maximum tolerable dose of Parathyroid Hormone-related Protein, PTHrP, or Parathyroid Hormone, PTH, that can be given safely over one week in healthy African-American volunteers. The investigators plan to infuse low doses of intravenous PTHrP or PTH to determine if it leads to a sustained and progressive suppression of bone formation as occurs in humoral hypercalcemia of malignancy (HHM) or an increase in bone formation as occurs in hyperparathyroidism (HPT). Additionally, the investigators will assess the direct influence of PTHrP and PTH on vitamin D metabolism, markers of bone turnover, and fractional excretion of calcium. These results will be compared to previous studies of Caucasian volunteers. Sponsor: University of Pittsburgh
Phase 1
Pharmacokinetics and Tolerability of Minodronic Acid and Food and Age Effects on the Pharmacokinetics
August 2014 - October 2014Study type: Interventional
The primary objective of the the study was to evaluate the pharmacokinetic properties of minodronic acid tablets following single and multiple oral administration in healthy Chinese subjects. Additionally, the effects of age and food on minodronic acid pharmacokinetics was also explored. Sponsor: Wuhan Union Hospital, China
Active, not recruiting
Phase 1
China HVT Safety, PK, PD
July 2014 - February 2015Study type: Interventional
This study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of denosumab administered subcutaneously to healthy adults in China. Sponsor: GlaxoSmithKline
July 2014 - December 2016Study type: Observational
BACKGROUND: One-year adherence to oral anti-osteoporosis medication (AOMs) was only about 30%. In recent years, efforts have been made to change the delivery of these medications from oral form to injection form every, 3, 6 or 12 months to increase adherence. However, both patients and providers are sometimes confused about the multiple choices. Also, patients may receive extra medications if providers did not keep tract of their previous AOM uses or patients may changes providers. There were urgent needs to provide AOM monitoring and management services to improve cares. OBJECTIVES: To establish a anti-osteoporosis medication management service at National Taiwan University Hospital and its Beihu Branch. METHODS: Participating physicians will select those eligible for services and refer to study coordinators. Study coordinators will conduct baseline assessments on osteoporosis/fracture risks, record medical conditions, AOMs, provide educations on osteoporosis, fracture, sarcopenia, fall, medications, nutrition, and exercise. They also arrange return clinic visit, telephone reminder and follow up for patients, and communicate with providers on regular bases. the investigators plan to enroll 500 patients with 12-month follow up for each. Sponsor: National Taiwan University Hospital
Phase 4
Effectiveness of DiscontinuinG bisphosphonatEs Study: R21 Pilot Study
June 2014 - May 2015Study type: Interventional
This is a pilot study evaluating the recruitment strategies for sites and patients, data collection instruments, follow-up procedures, administrative processes, and the proposed management strategy for the future large scale national trial. This pilot study is 6 months in length. Sponsor: University of Alabama at Birmingham
Phase 4
Changes of Bone Turnover Markers and Bone Mineral Density After Osteoporosis Treatment
June 2014 -Study type: Interventional
To examine the changes of bone mineral density and bone turnover markers after Bonviva treatment in osteoporotic patients Sponsor: Shinshu University
Phase 4
Pathogenesis of Atypical Femur Fractures on Long Term Bisphosphonate Therapy
May 2014 - August 2018Study type: Observational
The purpose of this protocol is to determine the risk of atypical femoral shaft (thigh bone) fractures after long term fracture prevention therapy with a class of drugs called "bisphosphonates", colloquially referred to as Alendronate, risedronate, Ibandronate, and Zoledronate. In addition, the study is designed to find out which patient is most likely to develop this potential life changing complication and why. Finally, the results of this study will help clinicians to better understand the reason and thus tailor patient specific treatments…i.e., "the right treatment for the right patient for right duration." Sponsor: Henry Ford Health System
Phase 4
Changes of Bone Metabolic Markers and Bone Mineral Density After Denosumab and/or Teriparatide Treatment in Japanese Osteoporotic Patients
May 2014 -Study type: Interventional
It has not been well known about the changes of bone metabolic markers, bone mineral density and other bone-related markers after teriparatide and/or denosumab treatment in Japanese osteoporotic patients. Sponsor: Shinshu University
April 2014 - May 2017Study type: Observational
Osteoporosis is a public health problem. It is a skeletal disease being treated by Bisphosphonates as the first choice medication. The effects of these drugs were investigated for periodontal disease treatment both locally and systemically. However, it is very important to know their indirect effects on alveolar bone (i.e. their effects when used for treating osteoporosis). So, in this study, alternations that involve the alveolar bone when osteoporotic women use bisphosphonates will be studied radiologically using cone-beam CT and digital panoramic radiography. The goal is to provide dentists with information about changes in the characterization of the alveolar bone among these women. This is important for both periodontology and implantology. Maxillary and mandibular bone structural characterization among osteoporotic women had not been studied before. Furthermore, in an opposite direction, dental radiographs may aid in detecting osteoporosis. Osteoporotic women, under bisphosphonates therapy or not, will be invited to participate in this study. In addition, osteopenic and normal women regarding bone fragility will be included too, for comparison purposes. Panoramic radiographs will be taken. In addition, women under bisphosphonates for 6 months or more will be scanned by Cone -beam CT as it can give an idea about bone histomorphometry with a low radiation dose. Sponsor: Damascus University
Not yet recruiting
Phase 2
Denosumab Administration After Spinal Cord Injury
April 2014 - May 2018Study type: Interventional
Sublesional bone loss after acute spinal cord injury (SCI) is sudden, progressive, and dramatic. After depletion of bone mass and the loss of architectural integrity, it may be difficult, if even possible, to restore skeletal mass and strength. Denosumab is a relative new, highly potent anti-resorptive agent that has proven efficacy in postmenopausal osteoporosis to improve bone mass and in solid tumor patients to prevent a skeletal-related event to a greater extent than that with bisphosphonate administration. In persons with complete motor lesions, bisphosphonates have not been effective at reducing bone loss at the knee, the site of greatest relevance because of its increased risk of fracture. Anti-RANKL therapy appears to be more potent than bisphosphonates in animal models of bone loss due to immobilization, suggesting that treatment with denosumab may prove to be an efficacious therapy for persons with acute SCI to preserve bone mass and strength. Sponsor: James J. Peters Veterans Affairs Medical Center
The information found on this site has been provided by clinicaltrials.gov in accordance with their terms & conditions. Neither we (inclinicaltrials.com), the United States Government, U.S. Department of Health and Human Services, National Institutes of Health, National Library of Medicine, nor any of its agencies, contractors, subcontractors or employees of the United States Government make any warranties, expressed or implied, with respect to data found on this site, and, furthermore, assume no liability, or the results of such use, of any part of the data.


text:
Former LSU cornerback helps himself out Brad Biggs
Tyrann Mathieu showed up at the NFL Scouting Combine saying he had put "Honey Badger" behind him.
He's putting to rest concerns that he would not run well also.
Mathieu ran his first 40-yard dash in 4.43 seconds, unofficially, a solid time for the former LSU defensive back. Mathieu has a lot of damage control to do for his off-field actions and alleged drug issues but on the field he was a consistent playmaker. His second 40 time was 4.50 and the official time has yet to be posted.
Mathieu started 14 games during his career at LSU – 10 at cornerback, three as a nickel back and one at free safety. He was a dangerous man with the ball in his hands and could have return ability in the NFL, especially with the speed he displayed this morning at Lucas Oil Stadium.
Alabama cornerback Dee Milliner was faster. He clocked at 4.31 and 4.37, the kind of speed that will have him solidly positioned in the first round.
Follow me on Twitter: @BradBiggs
Brad Biggs covers the Bears for the Chicago Tribune
NFP's Introduction to Scouting Class is now registering for our Winter sessions! Save $200 if you register before December 1st! REGISTER NOW!
Check out our partners at TiqIQ for the best deals on all games on the 2014 NFL schedule.
NOV 20 Joel Corry
Will there be first ballot Hall of Famers in 2015?
A detailed look at the eight candidates vying for that unique honor.
NOV 18 Dion Caputi
Cleveland quarterback Brian Hoyer has overcome long odds to put his team in contention for a playoff berth.
NOV 13 Joel Corry
The NFL's most underpaid players
10 players who are delivering big returns for their respective franchises.


text:
Rachel Zoe and Anne Hathaway's Major Break Up Shocker
12 Celebrities Who Are Kind of Gross
The Embarrassing Reason Khloe Kardashian Knew She Needed to Lose Weigh
Watch Miley Cyrus Fall Down on Stage Wearing a Fake Butt
Emma Watson's Intentional "Side Boob"
Why Did Ariana Grande Ditch Her Signature Look?
15 Unquestionably Creepy Celebrities
16 Celebrities With Royal Blood
Nick Jonas Explains Hilarious Photoshopped Kim Kardashian Butt Pic
Inside Kim and Kanye's $20 Million Mega Mansion
Kelly Osbourne Shows Off Super Slim Waist
Inside The Lavish World of 1 Year Old North West
Kim Kardashian Talks Waist Training and Kylie's Lips
The Hottest Pictures of Old Celebrities When They Were Young
The Most Beautiful Baby In The World Has Arrived
14 Celebrity Moms Who Breastfeed in Public
Riches to Rags: 6 Celebs Evicted From Their Mansions
Watch Miley Cyrus Fall Down on Stage While Wearing a Fake Butt
Blue Ivy Finally Starts to Look More Like Her Mom
Kim Kardashian Sparks a Cosmetic Surgery Trend
Kylie Jenner Addresses the Lip Injection Rumors Again
71-Year-Old Outsmarts Botox Surgeon, Looks 47
10 Pairs Of Stars Often Confused For Each Other
5 Country Music Girls That Could Easily Be the Next Taylor Swift
22 Celebrities Who Need SPANX Badly
20 Super Awkward Celebrities
Zayn Malik and Perrie Edwards Wedding Update
Bruce Jenner Rocks Red Nail Polish, Smokes Cig on His Birthday
Did Taylor Swift Write a Song On '1989' About Justin Bieber and Selena Gomez?
Selena's Scandalous Selfie Sparks Drama


text:
Know More About Registering and Paying
Building Partnerships and Collaboration across Sectors
Financial Management: Fundamentals for the Nonfinancial Manager
Fundraising Management: Developing, Managing and Evaluating Your Fund Development Plan
Marketing Management: Telling Your Organizations Story
Mastering Grant Writing: How to Write a Winning Grant Proposal
Nonprofits and Civic Engagement: An Introduction
Operations Management: Topics in Organizational Effectiveness
Public Policy Advocacy for Social Change
Strategic Management: Aligning Mission, Vision and Values
What Boards Do: Building Nonprofit Boards for Community and Organizational Leadership
Course Information
School of Continuing Studies
Engaging the New Volunteer Workforce: Attracting and Retaining Volunteers to Strengthen Your Organization and Effect Social Change
EVW / Non-Credit Course
Sixty-four million people volunteered at least once during 2012 (Source: Bureau of Labor Statistics) and the numbers are increasing. In this course, you will learn the growing importance of volunteerism today, how to attract and retain volunteers based on an understanding of their needs and interests and how to develop the organizational infrastructure necessary to sustain a volunteer program. Readings and discussion will also emphasize the global dimension of volunteering today.>This intensive five-week course explores the following topics: The new volunteer workforce: Changing roles, changing demographics. Common barriers to effective volunteer management. Best practices: Developing a strategic volunteer plan. Translating for-profit skills to nonprofit agencies. Wrap up: Attracting, retaining, evaluating and recognizing volunteers in your organization.>Learning Objectives What you and your organization will gain from this course: Working knowledge of the changing scope and composition of todays volunteer workforce. Understand common barriers to the effective use of volunteers and identify strategies to overcome them. Learn the benefits of and basic steps towards developing a strategic volunteer plan. Understand how for-profit skills and competencies translate to nonprofit organizations. Access to the best volunteer management resources online.>Special features of this course: A weekly Resource Center, which provides carefully tailored readings and other resources. Studio activities offer opportunities for new and experienced practitioners to cultivate practical skills. Original case studies and problem-based learning activities. In-depth weekly discussions on the real-life challenges and opportunities of volunteer management. A small class size of 25 participants.This is an instructor-led course delivered entirely online. It is highly interactive and requires active participation on discussions boards and completion of assigned projects. There are no real-time class meetings. Students work at times that are convenient for them within the weekly schedule of activities. We estimate spending an average of 8 10 hours per week on each Certificate in Nonprofit Management course. For this reason, we highly recommend students participate in no more than two CNM courses at a time.
NOTE: This is a tech-enhanced course that requires access to Blackboard, a course management system used by UIC. In order to complete registration, you must submit proof of identity to secure your unique NetID (username). More information on this process can be found on the Know More about Registering and Paying section of our Web site.
Cancellation/Refund Policy
For additional information about the course, please click here.
Section 1 (0415)
March 19 - April 22, 2015
|Course Fee: $550
Registration Deadline: Monday, March 16, 2015
|Location: University of Illinois at Chicago


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text:
Premier League team news
The meeting of Arsenal and Manchester United is the pick of the games on Saturday - while 24 hours later Liverpool and Spurs will be looking to kick-start their seasons when they visit Crystal Palace and Hull respectively
The meeting of Arsenal and Manchester United is the pick of the games on Saturday - while 24 hours later Liverpool and Spurs will be looking to kick-start their seasons when they visit Crystal Palace and Hull respectively
Arsenal manager Arsene Wenger believes no-one is capable of challenging Chelsea for the Barclays Premier League title at the moment.
Swansea stunned Arsenal with two late goals to run out 2-1 winners and inflict the Gunners' second Premier League defeat of the season at the Liberty Stadium.
Arsene Wenger slammed his players' weak mentality after Arsenal threw away a three-goal lead to draw 3-3 with Anderlecht in the Champions League.
Arsenal spurned the chance to book their place in the Champions League knockout stages as they threw away a three-goal lead to draw 3-3 with Anderlecht.
Jack Wilshere has been ruled out of Arsenal's Champions League match against Anderlecht on Tuesday night through illness.
Alexis Sanchez scored twice as Arsenal moved back into the top four of the Premier League with a 3-0 victory over stubborn Burnley at the Emirates Stadium.
Alexis Sanchez made the most of howlers from Wes Brown and Vito Mannone as Arsenal claimed a 2-0 victory at Sunderland.
Manager Arsene Wenger is confident Arsenal can use their dramatic stoppage-time victory at Anderlecht as a springboard to secure qualification for the knockout stages of the Champions League once again.
Manager Arsene Wenger has challenged his Arsenal side to add the "fraction more" to their game and deliver a winning performance away to Anderlecht.
Arsenal left it late but goals at the death secured a 2-1 Champions League win over Anderlecht in Belgium.
UEFA has dropped its disciplinary proceedings against Arsenal relating to their Champions League meeting with Galatasaray earlier this month.
Danny Welbeck netted a stoppage-time equaliser as injury-hit Arsenal fought back to draw 2-2 against Hull at the Emirates Stadium.
Arsenal manager Arsene Wenger has confirmed that Mesut Ozil faces around six weeks out with a knee ligament injury, a problem that was only discovered when the midfielder joined up with the Germany squad for international duty last week.
Theo Walcott returned to full training with Arsenal today following his lengthy absence with a knee injury.
Arsenal's injury problems continue to mount up after central defender Laurent Koscielny was released from international duty with France.
Arsenal manager Arsene Wenger shoved Jose Mourinho as their long-running feud turned physical in a 2-0 win which saw Chelsea take a five-point lead at the top of the Premier League.
Arsene Wenger has made light of his shove on Chelsea boss Jose Mourinho during Arsenal's 2-0 defeat at Stamford Bridge, with the Portuguese also playing down the incident.
Chelsea manager Jose Mourinho declined the opportunity to apologise for describing Arsene Wenger as "a specialist in failure" ahead of Sunday's Premier League contest with Arsenal.
There's another busy weekend of Premier League soccer in store with Everton's trip to Manchester United and the clash of Arsenal and Chelsea being the main highlights. Get all the latest team news here.


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The Moxon rectangle, what matters?
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Testing The AMD Kaveri GPU Burst Turbo/Extreme
Published on 20 January 2014 09:39 AM EST
Written by
Michael Larabel
6 Comments
Offered through the UEFI interface on the ASUS A88X-PRO motherboard with the new AMD A10-7850K "Kaveri" APU is a "GPU Burst" mode with auto, turbo, and extreme settings. In this article this performance option for Kaveri's Radeon R7 Graphics is going to be tested under Ubuntu Linux.
This is the latest of already many
AMD Kaveri Linux articles
published on Phoronix since the chip's debut last week. This is just some straight-forward benchmarks to see how much of an impact the "GPU Burst" mode has on the A10-7850K's OpenGL gaming performance.
The ASUS motherboard by default has the value set to the "Auto" mode, which runs the GPU at its stock 720 MHz frequency. When setting the "Turbo" option the AMD Catalyst Linux driver was reporting a peak core frequency of 900 MHz, and under "Extreme" the peak frequency of the graphics core was 960MHz. During all of this testing the system memory was consistent at DDR3-2133MHz (in a separate article will be new benchmarks looking at the overall Kaveri DDR3 memory scaling performance).
The benchmarks from this GPU Burst mode comparison for the Kaveri APU on Ubuntu Linux with the Catalyst binary driver can be found on
from the
Phoronix Test Suite
produced results:
Hit up that link for all of the system details and results but the short synopsis is:
For many Linux OpenGL workloads it made little to no difference when under the "Turbo" or "Extreme" GPU modes for the A10-7850K.
GpuTest showed some best-case results when playing around with this ASUS UEFI motherboard option. Now check out
the rest of the Linux performance data
6 Comments
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About The Author
Michael Larabel is the principal author of Phoronix.com and founded the web-site in 2004 with a focus on enriching the Linux hardware experience and being the largest web-site devoted to Linux hardware reviews, particularly for products relevant to Linux gamers and enthusiasts but also commonly reviewing servers/workstations and embedded Linux devices. Michael has written more than 10,000 articles covering the state of Linux hardware support, Linux performance, graphics hardware drivers, and other topics. Michael is also the lead developer of the
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