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Publications (117)569.69 Total impact
Article: Long-term survival and conditional survival of cancer patients in Japan using population-based cancer registry data.[Show abstract] [Hide abstract]
ABSTRACT: Although we usually report five-year cancer survival using population-based cancer registry data, nowadays, many cancer patients have been able to survive longer and need to be followed-up for more than five years. Long-term cancer survival figures were scarce in Japan. We reported ten-year cancer survival and conditional survival using an established statistical approach. We received data on 1,387,489 cancer cases from six prefectural population-based cancer registries in Japan, diagnosed between 1993 and 2009 and followed-up for at least five years. We estimated the ten-year relative survival of patients who were followed-up between 2002 and 2006 using period analysis. Using this ten-year survival, we also calculated the conditional five-year survival for cancer survivors who lived for some years after diagnosis. We reported ten-year survival and conditional survival of 23 types of cancer for 15-99 year-old patients and 4 types of cancer for child (0-14 years old) and adolescent and young adult (AYA, 15-29 years old) patients by sex. Variation in ten-year cancer survival by site was wide, from 5% for pancreatic cancer to 95% for female thyroid cancer. About 70-80% of child and AYA cancer patients survived for more than ten years. Conditional five-year survival for most cancer sites increased according to years, while those for liver cancer and multiple myeloma did not increase. We reported ten-year cancer survival and conditional survival using population-based cancer registries in Japan. It is important for patients and clinicians to report these relevant figures using population-based database. This article is protected by copyright. All rights reserved.Cancer science. 09/2014;
Article: Family history, body mass index and survival in Japanese patients with stomach cancer: A prospective study[Show abstract] [Hide abstract]
ABSTRACT: Family history and nutritional status may affect the long-term prognosis of stomach cancer, but evidence is insufficient and inconsistent. To clarify the prognostic factors of stomach cancer, we conducted a prospective study of 1,033 Japanese patients with histologically confirmed stomach cancer who were admitted to a single hospital between 1997 and 2005. Family history of stomach cancer and pretreatment body mass index (BMI) were assessed using a self-administered questionnaire. Clinical data were retrieved from a hospital-based cancer registry. All patients were completely followed up until December, 2008. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated according to family history in parents and siblings and BMI category. During a median follow-up of 5.3 years, 403 all-cause and 279 stomach cancer deaths were documented. Although no association with family history was observed in the patients overall, analysis according to age group found an increased risk of all-cause death associated with a history in first degree relatives (HR = 1.61, 95% CI: 0.93-2.78, p = 0.09) and with a parental history (HR = 1.86, 95% CI: 1.06-3.26) among patients aged under 60 years at diagnosis. BMI was related to all-cause and stomach cancer death among patients aged 60 and over, showing a J-shaped pattern (HR of all-cause death = 2.28 for BMI<18.5; HR = 1.61 for 25≤ vs. ≥23.0 to <25.0 kg/m2). A family history of stomach cancer, especially parental history, may affect mortality among younger stomach cancer patients, whereas nutritional status may be a prognostic factor in older patients. © 2014 Wiley Periodicals, Inc.International Journal of Cancer 05/2014; · 6.20 Impact Factor
Article: Burden of Total and Cause-Specific Mortality Related to Tobacco Smoking among Adults Aged ≥45 Years in Asia: A Pooled Analysis of 21 Cohorts.[Show abstract] [Hide abstract]
ABSTRACT: Tobacco smoking is a major risk factor for many diseases. We sought to quantify the burden of tobacco-smoking-related deaths in Asia, in parts of which men's smoking prevalence is among the world's highest. We performed pooled analyses of data from 1,049,929 participants in 21 cohorts in Asia to quantify the risks of total and cause-specific mortality associated with tobacco smoking using adjusted hazard ratios and their 95% confidence intervals. We then estimated smoking-related deaths among adults aged ≥45 y in 2004 in Bangladesh, India, mainland China, Japan, Republic of Korea, Singapore, and Taiwan-accounting for ∼71% of Asia's total population. An approximately 1.44-fold (95% CI = 1.37-1.51) and 1.48-fold (1.38-1.58) elevated risk of death from any cause was found in male and female ever-smokers, respectively. In 2004, active tobacco smoking accounted for approximately 15.8% (95% CI = 14.3%-17.2%) and 3.3% (2.6%-4.0%) of deaths, respectively, in men and women aged ≥45 y in the seven countries/regions combined, with a total number of estimated deaths of ∼1,575,500 (95% CI = 1,398,000-1,744,700). Among men, approximately 11.4%, 30.5%, and 19.8% of deaths due to cardiovascular diseases, cancer, and respiratory diseases, respectively, were attributable to tobacco smoking. Corresponding proportions for East Asian women were 3.7%, 4.6%, and 1.7%, respectively. The strongest association with tobacco smoking was found for lung cancer: a 3- to 4-fold elevated risk, accounting for 60.5% and 16.7% of lung cancer deaths, respectively, in Asian men and East Asian women aged ≥45 y. Tobacco smoking is associated with a substantially elevated risk of mortality, accounting for approximately 2 million deaths in adults aged ≥45 y throughout Asia in 2004. It is likely that smoking-related deaths in Asia will continue to rise over the next few decades if no effective smoking control programs are implemented. Please see later in the article for the Editors' Summary.PLoS Medicine 04/2014; 11(4):e1001631. · 15.25 Impact Factor
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ABSTRACT: To evaluate dietary patterns in relation to colorectal cancer risk in Japanese. We prospectively assessed the association between dietary patterns among the Japanese and the risk of colorectal cancer. Dietary information was collected from 44,097 Japanese men and women aged 40-79 years without a history of cancer at the baseline in 1994. During 11 years of follow-up, we documented 854 cases of colorectal cancer, which included 554 cases of colon cancer and 323 cases of rectal cancer. Factor analysis (principal component analysis) based on a validated food frequency questionnaire identified three dietary patterns: (1) a Japanese dietary pattern, (2) an "animal food" dietary pattern, and (3) a high-dairy, high-fruit-and-vegetable, low-alcohol (DFA) dietary pattern. After adjustment for potential confounders, the DFA pattern was inversely associated with the risk of colorectal cancer (hazard ratio of the highest quartile vs the lowest, 0.76; 95 % confidence interval 0.60-0.97; p for trend = 0.02). When colon and rectal cancers were separated, the inverse association between the DFA pattern and cancer risk was observed for rectal cancer (p for trend = 0.003), but not for colon cancer (p for trend = 0.43). No apparent association was observed for either the Japanese dietary pattern or the "animal food" dietary pattern. The DFA dietary pattern was found to be inversely associated with the risk of colorectal cancer. This association was observed for rectal cancer, but not for colon cancer.Cancer Causes and Control 03/2014; · 3.20 Impact Factor
Article: Cigarette smoking and breast cancer risk in relation to joint estrogen and progesterone receptor status: a case-control study in Japan.[Show abstract] [Hide abstract]
ABSTRACT: An association of cigarette smoking with breast cancer risk has been hypothesized. However, results from previous studies have been inconsistent. This case-control study investigated the association of cigarette smoking with breast cancer risk in terms of estrogen-receptor/progesterone-receptor (ER/PgR) status. From among female patients aged 30 years and over admitted to a single hospital in Japan between 1997 and 2011, 1,263 breast cancer cases (672 ER+/PgR+, 158 ER+/PgR-, 22 ER-/PgR+, 308 ER-/PgR- and 103 missing) and 3,160 controls were selected. History of smoking (ever, never), some smoking-related measures, and passive smoking from husbands (ever, never) were assessed using a self-administered questionnaire. Polytomous logistic regression and tests for heterogeneity across ER+/PgR + and ER-/PgR- were conducted. For any hormone receptor subtype, no significant association was observed between history of smoking (ever, never) and breast cancer risk. Analysis of smoking-related measures revealed that starting to smoke at an early age of ≤19 years was significantly associated with an increased risk of postmenopausal ER-/PgR- cancer (odds ratio = 7.01, 95% confidence interval: 2.07-23.73). Other measures of smoking such as the number of cigarettes per day, the duration of smoking, and start of smoking before the first birth were not associated with breast cancer risk for any receptor subtype. There was no association between passive smoking (ever, never) and breast cancer risk for any of the four subtypes. These results indicate that history of smoking and passive smoking from husbands may have no overall effect on breast cancer risk for any hormone receptor subtype. However, it is possible that women who start to smoke as teenagers may have a higher risk of developing postmenopausal ER-/PgR- cancer. Further studies are needed to clarify the association of smoking with breast cancer risk, especially the role of starting to smoke at an early age.SpringerPlus 01/2014; 3:65.
Article: Stroke mortality associated with environmental tobacco smoke among never-smoking Japanese women: A prospective cohort study[Show abstract] [Hide abstract]
ABSTRACT: Objective This study examined the association of exposure to environmental tobacco smoke (ETS) during adulthood with stroke and its subtypes using data from a large-scale prospective cohort study in Japan. Methods The study population included 36,021 never-smoking Japanese women who were enrolled between 1983 and 1985 and were followed-up for 15 years. We used Cox proportional hazard regression models to estimate hazard ratios (HRs) for stroke death associated with ETS exposure at home during adulthood. Results A total of 906 cases of stroke death were observed during 437,715 person-years of follow-up. Compared with never-smoking women without smoking family members, HRs for stroke mortality among never-smoking women living with smoking family members in all subjects, in those aged 40–79 years, and in those aged ≥ 80 years were 1.14 (95% confidence interval: 0.99–1.31), 1.24 (95% CI: 1.05–1.46), and 0.89 (95% CI: 0.66–1.19), respectively, after adjustment for possible confounders. The risk was most evident for subarachnoid hemorrhage [HR: 1.66 (95% CI: 1.02–2.70) in all subjects]. Conclusion This study suggests that exposure to ETS at home during adulthood is associated with an increased risk of stroke among never-smoking Japanese women.Preventive Medicine. 01/2014; 67:41–45.
Article: Consumption of fruits, vegetables, and seaweeds (sea vegetables) and pancreatic cancer risk: The Ohsaki Cohort Study[Show abstract] [Hide abstract]
ABSTRACT: Studies on the effects of consumption of fruits, vegetables, and seaweeds on the incidence of pancreatic cancer are not conclusive. We examined the association (if any) between the consumption of fruits, vegetables, and seaweeds and the risk of pancreatic cancer in Japan. Data from 32,859 participants registered in the Ohsaki National Health Insurance Cohort Study who were 40–79 years old and free of cancer at baseline were analyzed. Consumption of fruits, vegetables, and seaweeds was assessed at baseline using a self-administered food frequency questionnaire (containing 40 items). Incidences of pancreatic cancer were identified by computer linkage with the Miyagi Prefectural Cancer Registry. During 11 years of follow-up, 137 pancreatic cancers (67 men and 70 women) were identified. The hazard ratios (95% confidence interval) of pancreatic cancer risk for the highest versus the lowest tertile were 0.82 (0.40–1.68, trend P = 0.57) in men and 0.64 (0.35–1.20, trend P = 0.22) in women for total consumption of fruits, 0.89 (0.46–1.73, trend P = 0.76) in men and 0.67 (0.33–1.35, trend P = 0.23) in women for total consumption of vegetables, and 0.92 (0.46–1.84, trend P = 0.81) in men for consumption of seaweeds (results for the consumption of seaweeds in women were not analyzed because of poor reliability), respectively. Total consumption of fruits, vegetables, and seaweeds was not associated with a reduced risk of pancreatic cancer.Cancer Epidemiology. 01/2014;
Article: Short-Term Projection of Cancer Incidence in Japan Using an Age-Period Interaction Model with Spline Smoothing.[Show abstract] [Hide abstract]
ABSTRACT: In Japan, population-based cancer incidence data are reported several years behind the latest year of cancer mortality data. To bridge this gap, we aimed to determine a short-term projection method for cancer incidence. Data between 1985 and 2007 were obtained from the population-based cancer registries in four prefectures (Miyagi, Yamagata, Fukui and Nagasaki). Three projection models were examined: generalized linear model with age and period (A + P linear); generalized linear model with age, period and their interactions (A*P linear); and generalized additive model with age, period and their interactions smoothed by spline (A*P spline). We performed a 5-year projection for the years 2000 and 2005, based on the data of 1985-95 and 1985-2000, respectively. Seven cancer sites (stomach, liver, colorectal, lung, female breast, cervix uteri and prostate) and all cancers combined were analyzed. The accuracy of projection was evaluated by whether each observed number fell within the 95% confidence interval of the projected number. The A*P spline model accurately projected 8 of 13 cancer site-sex combinations, whereas the number of site-sex combinations of accurate projection was 2 and 6 for A + P linear and A*P linear models, respectively. For liver and colorectal cancers, the A*P spline model alone performed accurate projections; the relative differences between projected and observed numbers of cancer incidence ranged between -0.4 and +10.9% for the A*P spline, and between +7.4 and +37.6% for the other two models. All three models failed to project sudden increases in prostate cancer between 2000 and 2005. The A*P spline model is a candidate method for the projection of cancer incidence in Japan. However, we need a continuous validation for prostate cancer.Japanese Journal of Clinical Oncology 11/2013; · 1.90 Impact Factor
Article: Cigarette smoking and lung cancer risk according to histologic type in Japanese men and women.[Show abstract] [Hide abstract]
ABSTRACT: Although cigarette smoking is a well-known risk factor for lung cancer, histology-specific risk has not been fully clarified in Japan. This case-control study evaluated the associations between smoking and lung cancer risk according to sex and histologic type. From among patients aged 30 yrs and over admitted to a single hospital in Japan between 1997 and 2009, 1,670 lung cancer cases and 5,855 controls were selected. History of smoking, quantity and duration of smoking, and passive smoking from spouses were assessed using a self-administered questionnaire. Odds ratios (ORs) and 95% confidence intervals (CIs) for each exposure were estimated by unconditional logistic regression. Ever-smoking was significantly associated with a higher risk of squamous cell and small cell carcinoma. The OR for these two histologic types combined was larger in women (OR = 24.98, 95% CI: 13.50-46.23) than in men (OR = 9.43, 95% CI: 5.73-15.51). Analysis of the quantity and duration of smoking showed that the OR for each exposure level tended to be larger in women than in men. For adenocarcinoma, clear positive associations with quantity and duration-related factors were observed among men, and a significant positive association with passive smoking from spouses was found among non-smoking women (OR = 1.44, 95% CI: 1.06-1.95). These results suggest sex- and histologic type- differences in the association of smoking with lung cancer risk. Although smoking control should be continued to prevent lung cancers, further studies are required to better clarify differences in smoking-related lung cancer risk between the sexes and histologic types. This article is protected by copyright. All rights reserved.Cancer Science 08/2013; 104(11):1515–1522. · 3.48 Impact Factor
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ABSTRACT: Background:Epidemiological evidence regarding the effect of coffee on the incidence of prostate cancer is inconsistent. We aimed to investigate coffee consumption and the risk of prostate cancer risk in a general Japanese population.Methods:We conducted a prospective cohort study in Ohsaki city, Japan, where 18 853 men aged 40-79 years participated in a baseline survey. Coffee consumption was assessed via a validated self-administered questionnaire. During 11 years of follow-up (from January 1 1995 to December 31, 2005), 318 incident cases of prostate cancer were detected. The Cox proportional hazards regression model was used to calculate the hazard ratios (HRs) and 95% confidence interval (CIs).Results:There was a significant inverse association between coffee consumption and the incidence risk of prostate cancer. Compared with those who did not drink coffee, the multivariate adjusted HRs were 0.81 (95% CI: 0.61-1.07), 0.73 (95% CI: 0.53-1.00), and 0.63 (095% CI: 0.39-1.00) for those who drank coffee occasionally, 1-2 cups per day, and 3 cups per day, respectively, with a P for trend of 0.02.Conclusion:This prospective finding from a Japanese population adds evidence that coffee intake is inversely associated with the incidence of prostate cancer.British Journal of Cancer advance online publication 14 May 2013; doi:10.1038/bjc.2013.238 www.bjcancer.com.British Journal of Cancer 05/2013; · 5.08 Impact Factor
Article: Anthropometric factors, physical activity, and breast cancer risk in relation to hormone receptor and menopausal status in Japanese women: a case-control study.[Show abstract] [Hide abstract]
ABSTRACT: PURPOSE: The associations between anthropometric factors, physical activity (PA), and breast cancer risk in terms of estrogen-receptor/progesterone-receptor (ER/PgR) status have been unclear in Japanese women. This case-control study was designed to evaluate these associations. METHODS: From among female patients aged 30 years and over admitted to a single hospital in Japan between 1997 and 2009, 1,017 breast cancer cases (538ER+/PgR+, 125ER+/PgR-, 23 ER-/PgR+, 249 ER-/PgR-, and 82 missing) and 2,902 controls were selected. Height, weight, body mass index (BMI) (kg/m(2)), and time spent exercising (hours/week) were assessed using a self-administered questionnaire. Polytomous logistic regression analysis and tests for heterogeneity across ER+/PgR+ and ER-/PgR- were conducted. RESULTS: Higher BMI was associated with a higher risk of ER+/PgR+ cancer among women overall [odds ratio (OR) = 2.41, 95 % confidence interval (CI) 1.37-4.23 for BMI ≥30.0; P trend = 0.0001] and postmenopausal women (OR = 6.24, 95 % CI 2.68-14.53 for BMI ≥30.0; P trend < 0.0001). A longer time spent exercising (more than 5 h/week) showed a decreased risk for any type of breast cancer among overall and pre- and postmenopausal women, although this did not reach statistical significance. Height was not associated with any risk. CONCLUSIONS: Higher BMI is associated with an increased risk of ER+/PgR+ cancer among women overall and postmenopausal women. PA might be associated with a decreased risk of any type. To prevent breast cancer, weight control and PA are important.Cancer Causes and Control 03/2013; 24(5):1033-1044. · 3.20 Impact Factor
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ABSTRACT: OBJECTIVE: The analysis of cancer trends in Japan has only been sporadically reported. We present a comprehensive report on the trends in cancer incidence and mortality in Japan using the most recent population-based data. METHODS: National cancer mortality data between 1958 and 2011 were obtained from published vital statistics. Cancer incidence data between 1985 and 2007 were obtained from high-quality population-based cancer registries of four prefectures (Miyagi, Yamagata, Fukui and Nagasaki). Joinpoint regression analysis was performed to examine the trends in age-standardized rates of cancer incidence and mortality. RESULTS: All-cancer mortality decreased from the mid-1990s, with an annual percent change of -1.3% (95% confidence interval: -1.4, -1.3), while all-cancer incidence continually increased from 1985, with an annual percent change of 0.7% (95% confidence interval: 0.6, 0.8). Major cancer sites, particularly the liver, colorectum and lung (males), showed a pattern of increasing incidence and mortality rates until the mid-1990s, stabilizing or decreasing thereafter. Stomach cancer showed a long-term decreasing trend for both incidence and mortality, while female breast cancer showed a continuously increasing trend. The incidence of prostate cancer, particularly at the localized stage, increased rapidly between 2000 and 2003, while that of mortality decreased from 2004. No changes were detected in the incidence or mortality for colorectal, female breast or cervical cancers after the establishment of national screening programs for these cancers. CONCLUSIONS: The analysis of cancer trends in Japan revealed a recent decrease in mortality and a continuous increase in incidence, which are considered to reflect changes in the underlying risk factors such as tobacco smoking and infection, and are partially explained by early detection and improved treatment.Japanese Journal of Clinical Oncology 03/2013; · 1.90 Impact Factor
Article: Lactation pattern and the risk for hormone-related female cancer in Japan: the Ohsaki Cohort Study.[Show abstract] [Hide abstract]
ABSTRACT: Although breastfeeding is associated with a reduction in the risk for breast cancer, its relationship with another hormone-related female cancer, endometrial cancer, has not been fully investigated. The objective of the present study was to prospectively examine the association between lactation pattern and the risk for incidence of breast cancer and endometrial cancer in Japanese women. We analyzed data for 26 680 women registered in the Ohsaki National Health Insurance Cohort Study, who were 40-79 years old at the baseline. During the 11 years of follow-up, we identified 148 incident cases of breast cancer and 32 incident cases of endometrial cancer. Compared with breastfeeding only, multivariate hazard ratios and 95% confidence intervals for the risk of breast cancer incidence were 1.12 (0.92-1.37) for women who had performed mixed feeding and 1.80 (1.14-2.86) for those who fed their babies only with formula (P-trend=0.014). For endometrial cancer incidence, multivariate hazard ratios and 95% confidence intervals were 1.32 (0.86-2.03) for women who had performed mixed feeding and 3.26 (1.23-8.61) for those who had performed only formula feeding (P-trend=0.018). Our findings appear to raise the possibility that nonbreastfeeding is positively associated with the risks for both breast cancer incidence and endometrial cancer incidence. Confirmation of our findings would require further investigation.European journal of cancer prevention: the official journal of the European Cancer Prevention Organisation (ECP) 03/2013; 22(2):187-92. · 2.21 Impact Factor
Article: Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: pooled analysis of prospective data from the Asia Cohort Consortium.[Show abstract] [Hide abstract]
ABSTRACT: To evaluate the association between body mass index and mortality from overall cardiovascular disease and specific subtypes of cardiovascular disease in east and south Asians. Pooled analyses of 20 prospective cohorts in Asia, including data from 835 082 east Asians and 289 815 south Asians. Cohorts were identified through a systematic search of the literature in early 2008, followed by a survey that was sent to each cohort to assess data availability. General populations in east Asia (China, Taiwan, Singapore, Japan, and Korea) and south Asia (India and Bangladesh). 1 124 897 men and women (mean age 53.4 years at baseline). Risk of death from overall cardiovascular disease, coronary heart disease, stroke, and (in east Asians only) stroke subtypes. 49 184 cardiovascular deaths (40 791 in east Asians and 8393 in south Asians) were identified during a mean follow-up of 9.7 years. East Asians with a body mass index of 25 or above had a raised risk of death from overall cardiovascular disease, compared with the reference range of body mass index (values 22.5-24.9; hazard ratio 1.09 (95% confidence interval 1.03 to 1.15), 1.27 (1.20 to 1.35), 1.59 (1.43 to 1.76), 1.74 (1.47 to 2.06), and 1.97 (1.44 to 2.71) for body mass index ranges 25.0-27.4, 27.5-29.9, 30.0-32.4, 32.5-34.9, and 35.0-50.0, respectively). This association was similar for risk of death from coronary heart disease and ischaemic stroke; for haemorrhagic stroke, the risk of death was higher at body mass index values of 27.5 and above. Elevated risk of death from cardiovascular disease was also observed at lower categories of body mass index (hazard ratio 1.19 (95% confidence interval 1.02 to 1.39) and 2.16 (1.37 to 3.40) for body mass index ranges 15.0-17.4 and <15.0, respectively), compared with the reference range. In south Asians, the association between body mass index and mortality from cardiovascular disease was less pronounced than that in east Asians. South Asians had an increased risk of death observed for coronary heart disease only in individuals with a body mass index greater than 35 (hazard ratio 1.90, 95% confidence interval 1.15 to 3.12). Body mass index shows a U shaped association with death from overall cardiovascular disease among east Asians: increased risk of death from cardiovascular disease is observed at lower and higher ranges of body mass index. A high body mass index is a risk factor for mortality from overall cardiovascular disease and for specific diseases, including coronary heart disease, ischaemic stroke, and haemorrhagic stroke in east Asians. Higher body mass index is a weak risk factor for mortality from cardiovascular disease in south Asians.BMJ (online) 01/2013; 347:f5446. · 17.22 Impact Factor
Article: Effect of screening mammography on cumulative survival of Japanese women aged 40-69 years with breast cancer.[Show abstract] [Hide abstract]
ABSTRACT: BACKGROUND: The effectiveness of screening mammography (MMG) has mainly been demonstrated by studies in western countries. This study was conducted to evaluate cumulative survival and the risk of breast cancer death among Japanese women aged 40-69 years with screening-detected and interval breast cancer divided into three groups: MMG with clinical breast examination (CBE), CBE alone, and self-detection. METHODS: By matching a list of 126,537 women (358,242 person-screenings) who participated in the Miyagi Cancer Society Screening program between 1 April 1995 and 31 December 2002 with the Miyagi Prefectural Cancer Registry, 429 MMG with CBE, 522 CBE, and 3,047 self-detected cases were included in this study. Follow-up was performed until the date of death or 31 December 2007. Survival was estimated by the Kaplan-Meier method. The Cox proportional hazards model was used to estimate hazard ratios (HR) and 95 % confidence intervals (CI) for breast cancer death. RESULTS: Five-year survival for women in the MMG with CBE, CBE, and self-detection groups was 96.8, 92.7, and 86.6 %, respectively. The HR (95 % CI) for breast cancer death was 2.38 (0.72-7.94) among CBE-screened and 4.44 (1.42-13.89) among self-detected cases for women aged 40-49 years, but was 3.00 (1.63-5.50) among CBE-screened and 4.51 (2.69-7.56) among self-detected cases for women aged 50-69 years relative to cases screened by use of MMG with CBE. CONCLUSIONS: In terms of the survival and risk of breast cancer death, MMG with CBE may be more effective than MMG alone or self-detection for Japanese women aged 40-69 years.Breast Cancer 12/2012; · 1.33 Impact Factor
Article: Cost-effectiveness analysis for breast cancer screening: double reading versus single + CAD reading.[Show abstract] [Hide abstract]
ABSTRACT: BACKGROUND: Computer-aided detection (CAD) increases breast cancer detection, but its cost-effectiveness is unknown for breast cancer screening in Japan. We aimed to determine whether screening mammography diagnosed by one physician using CAD is cost-effective when compared with the standard double reading by two physicians. METHODS: We established our model with a decision tree and Markov model concept based on feasible screening and clinical pathways, combined with prognosis of the health state transition of breast cancer. Cost-effectiveness analysis between double reading by two readers and single reading with CAD by one reader was performed from a social perspective in terms of the expected cost, life expectancy and incremental cost-effectiveness ratio (ICER). The hypothetical population comprised 50-year-old female breast cancer screening examinees. Only direct medical costs related to breast cancer screening and treatment were considered. One simulation cycle was 2 years, and the annual discount rate was 3 %. Sensitivity analysis was performed to evaluate the robustness of the model and input data. RESULTS: Single reading with CAD increased expected costs by 2,704 yen and extended life expectancy by 0.0087 years compared with double reading. The ICER was 310,805 yen per life year gained, which is below the threshold. Sensitivity analysis showed that the sensitivity and specificity of CAD and the number of breast cancer screening examinees greatly affected the results. CONCLUSIONS: Single reading using CAD in mammography screening is more cost-effective than double reading, although the results are highly sensitive to the sensitivity and specificity of CAD and the numbers of examinees.Breast Cancer 10/2012; · 1.33 Impact Factor
Article: Association of body mass index and risk of death from pancreas cancer in Asians: findings from the Asia Cohort Consortium.[Show abstract] [Hide abstract]
ABSTRACT: We aimed to examine the association between BMI and the risk of death from pancreas cancer in a pooled analysis of data from the Asia Cohort Consortium. The data for this pooled analysis included 883 529 men and women from 16 cohort studies in Asian countries. Cox proportional-hazards models were used to estimate the hazard ratios and 95% confidence intervals for pancreas cancer mortality in relation to BMI. Seven predefined BMI categories (<18.5, 18.5-19.9, 20.0-22.4, 22.5-24.9, 25.0-27.4, 27.5-29.9, ≥30) were used in the analysis, with BMI of 22.5-24.9 serving as the reference group. The multivariable analyses were adjusted for known risk factors, including age, smoking, and a history of diabetes. We found no statistically significant overall association between each BMI category and the risk of death from pancreas cancer in all Asians, and obesity was unrelated to the risk of mortality in both East Asians and South Asians. Age, smoking, and a history of diabetes did not modify the association between BMI and the risk of death from pancreas cancer. In planned subgroup analyses among East Asians, an increased risk of death from pancreas cancer among those with a BMI less than 18.5 was observed for individuals with a history of diabetes; hazard ratio=2.01 (95% confidence interval: 1.01-4.00) (P for interaction=0.07). The data do not support an association between BMI and the risk of death from pancreas cancer in these Asian populations.European journal of cancer prevention: the official journal of the European Cancer Prevention Organisation (ECP) 10/2012; · 2.21 Impact Factor
Article: Tubeimoside-1 inhibits growth via the induction of cell cycle arrest and apoptosis in human melanoma A375 cells[Show abstract] [Hide abstract]
ABSTRACT: Tubeimoside-1 (TBMS1) has been shown to possess promising anticancer potential against various cancer cells. However, its effect against melanoma cells remained enigmatic. In this study, for the first time, we investigated the effect of TBMS1 on cell proliferation, cell cycle, and apoptosis in melanoma A375 cells. In order to examine the effects of TBMS1 on cell proliferation, cell cycle, apoptosis, we performed MTT assays and flow cytometry analysis. The results revealed that TBMS1 decreased the cell viability of melanoma A375 cells. Flow cytometric analysis demonstrated that TBMS1 markedly induced apoptosis of A375 cells and arrested cell cycle at G2/M phase in a dosedependent manner. Induction of apoptosis involved a decrease in mitochondrial membrane potential, down-regulation of Bcl-2 and upregulation of Bax before culminating in apoptosis in TBMS1-treated A375 cells. These in vitro results suggested that TBMS1 should be further examined for in vivo activity and molecular mechanism in human melanoma.Bangladesh Journal of Pharmacology 08/2012; 7:150-156. · 0.36 Impact Factor
Article: Reproductive factors and breast cancer risk in relation to hormone receptor and menopausal status in Japanese women.[Show abstract] [Hide abstract]
ABSTRACT: The associations between menstrual and reproductive factors and breast cancer risk in relation to estrogen/progesterone receptor (ER/PgR) status have been unclear in Japanese women. This case-control study evaluated these associations, overall and separately, by menopausal status. A total of 1092 breast cancer cases and 3160 controls were selected from among female patients aged 30 years and over admitted to a single hospital in Miyagi Prefecture between 1997 and 2009. The receptor status distribution among the cases (missing: 8.4%) was 571 ER+/PgR+, 133 ER+/PgR-, 24 ER-/PgR+ and 271 ER-/PgR-. Menstrual and reproductive factors were assessed using a self-administered questionnaire. Polytomous logistic regression and tests for heterogeneity across ER+/PgR+ and ER-/PgR- were conducted. Later age at menarche was significantly associated with a decreased risk of both ER+/PgR+ and ER-/PgR- cancer among women overall (P(trend) = 0.0016 for ER+/PgR+; P(trend) = 0.015 for ER-/PgR-) and among postmenopausal women (P(trend) = 0.012 for ER+/PgR+; P(trend) = 0.0056 for ER-/PgR-). Nulliparity was associated with an increased risk of ER+/PgR+, but not ER-/PgR- cancer among women overall (P(heterogeneity) = 0.019) and among postmenopausal women (odds ratio for ER+/PgR+ = 2.56, 95% confidence interval = 1.61-4.07; P(heterogeneity) = 0.0095). A longer duration of breastfeeding tended to be associated with a decreased risk in all subtypes among women overall. Later age at menarche has a protective effect against both ER+/PgR+ and ER-/PgR- cancer. However, parity might impact differently on various subtypes of breast cancer. Further studies are needed to clarify the etiology of the rare ER+/PgR- and ER-/PgR+ cancer subtypes.Cancer Science 07/2012; 103(10):1861-70. · 3.48 Impact Factor
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ABSTRACT: Body mass index (BMI) may be an important factor affecting breast cancer outcome. Studies conducted mainly in Western countries have reported a relationship between higher BMI and a higher risk of all-cause death or breast cancer-specific death among women with breast cancer, but only a few studies have been reported in Japan so far. In the present prospective study, we investigated the associations between BMI and the risk of all-cause and breast cancer-specific death among breast cancer patients overall and by menopausal status and hormone receptor status. The study included 653 breast cancer patients admitted to a single hospital in Japan, between 1997 and 2005. BMI was assessed using a self-administered questionnaire. The patients were completely followed up until December, 2008. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated according to quartile points of BMI categories, respectively: <21.2, ≥21.2 to <23.3 (reference), ≥23.3 to <25.8 and ≥25.8 kg/m2. During the follow-up period, 136 all-cause and 108 breast cancer-specific deaths were observed. After adjustment for clinical and confounding factors, higher BMI was associated with an increased risk of all-cause death (HR = 2.61; 95% CI: 1.01-6.78 for BMI ≥25.8 vs. ≥21.2 to <23.3 kg/m2) among premenopausal patients. According to hormonal receptor status, BMI ≥25.8 kg/m2 was associated with breast cancer-specific death (HR = 4.95; 95% CI: 1.05-23.35) and BMI <21.2 kg/m2 was associated with all-cause (HR = 2.91; 95% CI: 1.09-7.77) and breast cancer-specific death (HR = 7.23; 95% CI: 1.57-33.34) among patients with ER + or PgR + tumors. Analysis by hormonal receptor status also showed a positive association between BMI and mortality risk among patients with ER + or PgR + tumors and with BMI ≥21.2 kg/m2 (p for trend: 0.020 and 0.031 for all-cause and breast cancer-specific death, respectively). Our results suggest that both higher BMI and lower BMI are associated with an increased risk of mortality, especially among premenopausal patients or among patients with hormonal receptor positive tumors. Breast cancer patients should be informed of the potential importance of maintaining an appropriate body weight after they have been diagnosed.BMC Cancer 04/2012; 12:149. · 3.33 Impact Factor
Top Journals
Xi'an Jiaotong UniversityCh'ang-an, Shaanxi, China
Miyagi Cancer CenterСендай, Miyagi, Japan
Iwate Prefectural Central HospitalAomori, Aomori Prefecture, Japan
Tohoku University
Sendai, Kagoshima-ken, Japan
- • Division of Public Health and Forensic Medicine
- • Graduate School of Medicine
Icahn School of Medicine at Mount SinaiManhattan, New York, United States
Vanderbilt University
Nashville, MI, United States
- Division of Epidemiology
University Hospital Medical Information NetworkEdo, Tōkyō, Japan
Fujita Health University
Nagoya, Aichi, Japan
- Department of Public Health
Nagoya UniversityNagoya, Aichi, Japan
Aichi Cancer CenterŌsaka, Ōsaka, Japan
Miyagi UniversityJapan
National Cancer Research InstituteLondinium, England, United Kingdom
The University of Tokyo
Tokyo, Tokyo-to, Japan
- Department of Health Science and Nursing


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This is a known issue in the Lync mobile client (Microsoft Apps v1) and it has been fixed in the Microsoft Apps v2. If you don't want to use Lync, you can still close the application through the task switcher in your Nokia Belle device. Long press the menu key, and close the Lync app from the list of open apps.
Nokia 700 - Why is the Lync client always shown on the home screen when I start up the phone, even though I have never used it, and why cannot I close it?
Related FAQs
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- Can I have multiple mail accounts using ActiveSync on my Symbian^3 device?

subset: commoncrawl


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Home » News » Politics » Town Meetings
Litchfield town deliberative session set for Saturday
According to Town Administrator Jason Hoch, the recommended operating budget of $5,045,145 is about $80,000 more than the current budget.
"About $35,000 of that increase is the added cost from the New Hampshire Retirement System," said Hoch. "That is what everyone is dealing with right now."
Other adjustments to the budget include third-year wage increases from a police union contract and the anticipated hiring of four to six on-call firefighters, according to Hoch.
Voters will review 18 warrant articles, although some of them are typical housekeeping items. There is a request for $12,500 to be used for preliminary engineering costs to design a sidewalk on Pinecrest Road that would connect the bike path on Albuquerque Avenue with Litchfield Middle School. The fee, Hoch said, is just for the design plans; the actual construction costs will likely be presented to voters at the 2014 annual meeting. "We know how popular the Albuquerque Bike Path has become, so we want to get the ball rolling to eventually connect the path to all of the schools," he said. "This is step one towards doing that."
There is a separate request to allocate $10,000 to repair the entrance to the town hall and police station. The requested funds, according to Hoch, are leftover from the town hall roof replacement last year.
"There is severely deteriorated concrete at the front entrance," he said, adding the existing columns at the entryway also need to be repaired.
Residents also will be asked to appropriate $20,000 to repaint the old town hall, $10,000 for an engineering study to determine possible designs for a wastewater sewer system and nearly $19,000 for a 2 percent cost of living adjustment for nonunion town and library employees.
Another warrant article, which is advisory only, seeks to gain public comment about the current official ballot voting, or SB2 form currently used by the town. The article asks for insight into whether town residents would like to revert to the traditional town meeting for conducting its annual meeting.
"If there is interest to go back to the traditional town meeting style, then it will be placed on the warrant next year to discuss the merits of each type of government," said Hoch.
Saturday's deliberative session begins at 10 a.m. at Campbell High School, 1 Highlander Court.
The school district's deliberative session will begin at 7 p.m. Wednesday at the high school.
Election Day is March 12.
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Faculty and alumni gathered for a keynote speech by Chicago Mayor Rahm Emanuel and participated in breakout sessions at the 62nd annual Management Conference. Read more »
Applying Artistry in Business »
The Remarkable Journeys of Booth's Renowned Quants »
Alumni View: Women in Leadership »
For insights on the upcoming economic landscape from Randall S. Kroszner, Austan D. Goolsbee (pictured), and Carl R. Tannenbaum, AB '81, MBA '84, see coverage of Chicago's Economic Outlook. Learn more »
Monetary policy assessed at Management Conference keynote panel: Breakout sessions at the May 17 event focused on health care, private equity,
and the challenge of leaving a large corporation. Learn more »
Additional gift by benefactor Michael Polsky will enable the hub for entrepreneurship and innovation to serve the broader University of Chicago community. Learn more »
New York Alumni Breakfast Series with Jeremey Donovan, '02 11/21/2014
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Data Fit-Ness—Does It Drive Strategy In Your Organization? 11/21/2014
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SeedCon: Entrepreneurship and Venture Capital Conference 11/21/2014
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Originally published Saturday, June 23, 2012 at 4:09 PM
4 die in Gaza as violence escalates
At least three people were killed and others were injured Saturday when Hamas and Israel disregarded a pledged cease-fire and resumed strikes on both sides of the Gaza border. The chief of the Israel Defense Forces called a meeting of military officials to determine the next course of action.
The New York Times
TEL AVIV, Israel — Despite a pledged cease-fire agreement between Hamas and Israel, strikes resumed on both sides of the Gaza border on Saturday, killing at least three Palestinian men and a 6-year-old boy in Gaza, and wounding an Israeli man in Sderot, officials said.
Signaling the seriousness of the renewed fighting, the chief of the Israel Defense Forces called an urgent meeting of senior military officials during the Sabbath to "determine the next course of action," according to a military spokeswoman, speaking on the condition of anonymity in line with regulations.
On Saturday afternoon, the armed wing of Hamas, known as the Qassam Brigades, promised to continue firing rockets in response to the Israeli airstrikes. "If the last round of confrontation ... was not enough to deter the occupation," it said in a statement, "we are ready to break its arrogance, stop its crimes and respond to its aggression." But a few hours later, Israel's Channel 2 news reported that a new Hamas cease-fire would begin Saturday night.
The renewed fighting comes just after the fifth anniversary of Hamas' taking of full control of the Gaza Strip, and amid an internal struggle for leadership of the party. Until last week, Hamas had largely adhered to an informal cease-fire for more than a year, though other militant Palestinian factions had frequently fired rockets into southern Israel. This latest flare-up began Monday with the killing of an Israeli construction worker building a fence along the border with Egypt.
Israeli military officials said 24 rockets fired from Gaza hit southern Israel on Saturday, part of a weeklong barrage of more than 150; 10 were intercepted.
A school and factory were among the sites hit, as officials urged residents to stay indoors.
Israel struck two Hamas sites in the northern Gaza Strip and one in the south on Saturday .A military spokeswoman said two suspected terrorists "about to launch rockets at Israel" were directly targeted in separate attacks.
Palestinian officials said the first attack killed Khaled al-Buri, who was affiliated with the Popular Resistance Committees, a group loyal to Hamas that claimed responsibility for firing dozens of rockets and missiles into Israel in recent days. The second attack was apparently aimed at a motorbike rider in Gaza City. But witnesses said he escaped unharmed, while the rocket hit an apartment building, sending bricks onto the street that killed Osama Ali, 42, and wounded 10 others.
And Saturday morning in the southern Gaza town of Khan Yunis, witnesses said, an Israeli artillery shell killed Ali al-Shawaf, 6, and wounded his father, who died later in the day.
Lt. Col. Avital Leibovich of the Israeli military said on Twitter that the boy had died in an explosion of Palestinian ordnance.
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Soundstage Review Music Hall MMF-5
When it comes to overall performance, to my ears, the sonic nod has to go to
the Music Hall MMF-5... You get so much music for the money that
it is downright ridiculous. Though the Pro-ject 'arm may ultimately fall
short of the RB250 as a standalone product, in this particular application
it more than holds its own, perhaps due in part to the more sophisticated
base and commensurate isolation. The total system synergy that you get with
the MMF-5 translates into heightened low-bass performance, increased dynamics,
greater resolution and remarkably enhanced low-level detail. While I am a
big fan of the Rega products, I find the Planar 2 and 3 to be somewhat reticent
in those particular areas. The MMF-5 is a highly involving, remarkably musical
little turntable. Click Here to read the entire review!
Stereophile Recommended Component
It'll make an analog believer out of the most doctrinaire digital fanatic.
Warm, sweet, open, and coherent, a gateway drug into the intoxicating world
of analog...Get hooked. You'll never go back. -Michael, Fremer (Vol.23 No.7)
The Absolute Sound Editor's Choice Award Winner for 2005 & 2006!
"Music Hall's integrated turntable package provides the LP lover with
a warm, musically engaging, and affordable vinyl playback solution. Its bass
isn't the most defined, and it's a bit forward in the upper midrange, but the
Music Hall is an outstanding value" -
The Absolute Sound, October 2006, Issue 165


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This Cyber Monday Tuts+ courses will be reduced to just $3 (usually $15). Don't miss out.
In today's tutorial, regular Cgtuts+ & Aetuts+ author Antonio Cerri will walk us through the creation of an animated science fiction style logo. We'll start off by modeling and animating the logo design in Cinema4D, before moving into After Effects for assembly and compositing.
Note: click the 'Monitor' icon to view tutorial in full-screen HD.
Translations Available:
Tuts+ tutorials are translated by our community members. If you'd like to translate this post into another language, let us know!
About Antonio Cerri
I am a freelancer in web, graphic and motion design for about 12 years. When he was young, I was always fascinated by the world of digital visual effects and 3D Motion Graphics, with a focus on impacts futuristic hi-tech. My passion for this work has grown increasingly, thanks to continuous research, but mainly thanks to experimentation, mixing all the graphic visual disciplines "Photography, Design type font, sound effects FX, etc.." For me it is very important, that at the end of writing work, they remain surprised and satisfied. For information and questions, please contact me through my website.+ Expand Bio- Collapse Bio


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Struggling Singapore Airlines fights back
Asia's second biggest airline desperately needs growth...
May 16, 2013 10:59 by Reuters
"SQ is giving its competition a very easy way to get experienced pilots," said one SIA pilot whose contract was cancelled this year, speaking on condition of anonymity because his contract was confidential.
Analysts are looking beyond quarterly numbers for strategic changes. JPMorgan said SIA had net cash of S$3.8 billion as of December and could potentially announce a special dividend.
Some of that cash will help pay for new aircraft including the Airbus A350s and additional Boeing 777-300ERs, plus Boeing 737s for its regional carrier Silkair.
Fong said though SIA has been able to manage costs better than its competitors and had a strong balance sheet, it needed to come up with a clearer strategy.
Over the past year, SIA agreed to sell a 49 percent stake in Virgin Atlantic Airways Ltd, started a new budget airline Scoot, expanded capacity at Silkair, and is potentially increasing its stake in affiliate Tiger Airways Holdings Ltd.
Still, SIA needs to do much more, some analysts said.
"What could they do better? Maybe, if they could find a way to get into China more aggressively?" said Andrew Orchard, Hong Kong-based analyst at brokerage CIMB. "Would they want to do a bilateral partnership with a Middle Eastern carrier, take out some capacity that way?"
Orchard said SIA should consider quitting Star Alliance and joining the rival SkyTeam network as it could potentially work more closely with Chinese airlines and other partners.
SIA is doubling its stake in Virgin Australia Holdings Ltd to 19.9 percent. This comes months after struggling Qantas Airways Ltd and Emirates struck a five-year alliance, which includes switching the Qantas' hub to Dubaifrom Singapore for European flights.
SIA's moves to buy into Chinese and Indian carriers many years ago have not borne fruit. Goh has said the airline needs to increase exposure to these high-potential markets, but rivals have a head start.
Last month, Etihad agreed to buy a 24 percent stake in Jet Airways Ltd, India's largest carrier, while AirAsia has struck a deal with the Tata group to start a local airline.
SIA's shares, trading at their highest level in 1-1/2 years, have gained more than 6 percent so far this year as analysts upgrade earnings estimates due to lower fuel costs.
AirAsia's cut-rate pricing on Southeast Asian routes and the emergence of new rivals such as the Lion Air group has hit SIA.
"Corporate travel in Asia has weakened but leisure travel is booming. That is helping to drive numbers but these are lower-spending travellers," said Fred Seow, vice president of marketing at Asiatravel.com, which operates several hotel and flight booking websites.
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That apple tree. Oh my goodness. Something told me it wouldn't turn out well.
A second-grade teacher writes: "I teach in a very competitive school where parents have developed a 'mob mentality' for bullying administrators and teachers. They have gone beyond helicopter parenting to Apache Blackhawk parenting."
This happened years ago. Mama was alive then, so it's been seven or eight years. I hadn't thought about in almost that many years but when it came to mind the other day, I took to studying on it and how the circumstances and opportunities of life's journey can be so fascinating.
Q: My 23-month-old son does well with potty training when we're at home. We use a "potty bell" and he goes every 90 minutes or so. When we're away from home, however, he seems clueless. He pees in his car seat about five minutes into a trip and simply will not use a potty anywhere but at our home or at my mother's (she watches him one day a week at her place). Would pull-ups be a bad thing to use when we leave the house?
Yes, I know that I am, occasionally, prone to embellishment. But trust me when I say this is the law and the gospel: I have a long-time friend who only calls me when someone dies. Most times, I know the person but sometimes I don't have a clue the person ever existed.
Q: I homeschooled my oldest, an 8-year-old boy, until this year. He started third grade in public school in August. As a homeschooling mom, I was not a micromanager and don't want to become one now, but the school virtually insists that parents help with homework. I want him to be independent. What are your thoughts on this?
A friend of mine, long embroiled in upsets, distractions, problems and tribulations, called one day to announce happily that she was learning to "let things roll right off my back."
It's a fact that a good night's sleep is essential to optimal performance, no matter the task. It is also a fact that America's teens, generally speaking, don't get enough sleep. Ergo, American teens, as a group, underperform in school.
As the old parenting point of view fell out of fashion beginning in the late 1960s, the vernacular that accompanied it all but completely disappeared. Today's parents don't say to their children the sorts of things parents said to children in the 1950s and before, things like, "You're acting too big for your britches again, young man."
It's a funny thing. That's what Mama used to say when something baffled her. Like Mama, I prefer that things make common sense. Otherwise, I'll ponder, figure, study, and try to decipher that funny thing until it's somewhat sensible.
One Sunday while sitting around the dinner table, Louise and I began to tell Daddy stories, the ones that stretched back to the early days of his preaching life. Since I was born 12 years after he "made a preacher," as our folks said back then, I could only contribute what he had told me about those days, not what I had seen.
Q: Our 5-year-old grandson sees his 5-year-old female first cousin from time to time. After they play for a while, he tells her he wants to "touch" her. This has happened twice in recent months. Her parents are very upset, but our grandson's parents read lots of parenting books and seem to think it's no big deal. Your thoughts on this matter?
To this conclusion I have come: the most deadly years of our lives are the ages 16 to 21. Those years give us a headiness that comes from new freedom - a driver's license - and the passing of the torch from strict childhood rules to more trust, different restraints and relaxed curfews.
On one of my Web sites I, along with a team of certified parent coaches, answer questions submitted by parents. In the last two days, 67 percent of the questions have concerned toilet training. A 3-year-old is afraid of the potty. A 26-month-old will only use the potty independently if he's not wearing clothes. A 23-month-old seems oblivious to mom's expectations. And so on.
The YMCA of Coastal Georgia will become a provider of the nationally recognized LIVESTRONG at the YMCA program, thanks to an implementation grant from YMCA of the USA, the Y's national resource office, in partnership with the LIVESTRONG Foundation.
For the last several Octobers among the evergreen pines and red, brown and yellow leaves of oak trees in Guyton, there have also been bright spots of pink. For three years now, "Paint the Park Pink" has been the theme for Mossy Oak Music Park's October bluegrass festival.
From the I'm Sorry to Have to Tell You Department: Parents who say they want to raise kids who "think for themselves" are not being exactly truthful. It's a nice and very democratic thing to say, for sure, but let's face it folks, you want your kids to think like you do. For example: if you're a liberal, you want your kids to be liberals when they grow up. Right? Right!
Mr. and Mrs. Joseph Steven Snooks of Springfield announce the engagement of their daughter, Emily Patrice Snooks, to Ryan James Burnside, son of Mr. Conrad Burnside of Suwanee and Ms. Catherine Saul Burnside of Duluth.
My husband was out of town, working on location, when he called one night and discovered that I was still working, though the hour had grown late.
Why are young adult children emancipating so much later than they did in 1970, when the average age of male emancipation (independent living, paying one's own bills) was 21? Why do significant numbers of college professors and even employers complain about parents of young adult students/employees confronting them over, respectively, bad grades and workplace issues? Why have reduced class sizes and increased per-pupil expenditures not resulted in higher academic achievement levels? Why is the mental health of today's kids so poor when compared with that of children in the 1960s and before? Why has school phobia, test ...
It happened a few months back. My father-in-law celebrated, to our great joy, his 88th birthday. There was no pomp or circumstance involved. He abhors that. Because he is among the most beautifully well-mannered people I have ever encountered, he politely took all the calls though he really wished we would just treat it as another day and leave him alone to watch the news channel.
Laughter is the best medicine, the old adage goes.
The annual Effingham County American Cancer Society memorial service will be held Sunday at 2:30 p.m. at the Effingham County Board of Education auditorium, 405 N. Ash St. in Springfield.
Family Promise of Effingham County recently held a ribbon cutting officially dedicating its day center on Laurel Street in Springfield. Joined by Effingham board members, executive director Ashley Moore cut the ribbon as part of the local activities for Family Promise Week.
It happened the other day. It's funny how things so simple can remind us of things so meaningful, of those sweets that are tucked inside our hearts and unknowingly treasured.
Q: My 6-year-old son argues with me about everything I tell him to do. He comes up with reason after reason why he shouldn't have to or can't, why it's unfair, or why, at the least, I should help him. I think he's got some argument disorder. Is there such a thing? In any case, it's beginning to drive me nuts, up a wall, and over the edge. Is there a solution?
It's time once again for me to clarify my position on spanking. I arrived at this reluctant conclusion because twice in the last week, I've been informed that I believe in it, which is not exactly true.
My parents, according to the world's definition of "cool," were not. Neither drank nor did either ever possess a credit card. Groceries and clothing were paid for in cash, utilities paid by check, and the only monthly payments they ever allowed themselves were a mortgage for a house, a short-term loan for another farm, and a couple of cars bought, over time, and paid for quickly.
Since the beginning of the 2014-15 school year, several elementary teachers have asked me why so many of today's kids come to school with anxiety issues. That's a good question, one that I think goes to the heart of contemporary American parenting.
A few years ago, the magazine I have long loved - Southern Living - changed. Like most Southerners, I have an aversion to change which is why our traditions have such a stranglehold. We never let go.
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Faith and Business
The Business of Heaven (Revelation 21:22–26)
November 12th, 2014
Every city across the globe has a role to play in the kingdom of God.
Dual Citizenship (Hebrews 13:14–16)
November 7th, 2014
Reflecting on our identity as dual citizens can help us pay attention to opportunities we might otherwise miss.
Investment Advice to the Exiles: Create Culture (Jeremiah 29:4-7)
October 29th, 2014
Had we stayed longer in Eden, we might have built cities and businesses unstained by sin. But we didn't.
Love and Money (1 Timothy 6:10-12)
October 1st, 2014
The key to "fighting the good fight" is to become better lovers.
Doing Glorified Work (2 Thessalonians 1:10–12)
September 24th, 2014
Our initiatives are songs of hope, prayerful offerings lifted heavenward.


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A British parliamentary committee advises a re-imposition of European economic sanctions on Burma if there is no improvement in the country's human rights situation.
Burma will struggle to attract new investment in the sector because of a global industry slump and new competition from neighboring countries, a report says.
Plans to "revitalize" with an economic corridor; Bagan's heritage bid will take time; Boeing inks deal with Air Mandalay; and China trade at Muse rises.
President Obama's visit will do little to boost US investment, Burma joins China-led regional bank, and Asian firms strongly interested in investing in Burma.
Winners of special economic zone contracts could decide fate of grand project
Doubts raised over long-term viability of Hantawaddy Airport deal; petrochemical industry needs know-how, investment; coal to play a big role in fueling Burma's electricity growth.
Burma's economic and social development will grind to a halt if rising military interference in politics delays the 2015 national elections, a business analysis warns.
Colgate buys a Burmese toothpaste brand; hotel redevelopment slated for a Rangoon courthouse; millions of motorbikes are smuggled; and changing Burma offers a fast-food frenzy.
Restricted at home, a Thai state-owned electricity firm wants to use Burma as a proxy supplier of electricity via environmentally damaging dams, an NGO says.
Tin industry surges; England to aid banking sector; MOGE will tender more energy blocks; Thai firm inks solar agreement; and US companies fund women's initiatives.
Thailand pushes for Dawei LNG terminal, Burma's economy grows faster than expected and jade mining resumes in Kachin State's troubled Hpakant.
Burma's chronic lack of electricity to power its economic development could be solved from an unlikely source underdeveloped neighboring Laos.
Thailand ignores UN migrant rights request; luxury trains planned for tourists; Japan banks win big; Rangoon port pollution worries; and economic reforms prioritized, group claims.
Annual rice exports in Burma are unlikely to meet the industry's target, as monsoonal rainfall needed to boost crops is expected to be below average.
Dams under scrutiny; Myawaddy border trade soars; neighboring garment sectors taken to task; visa on arrival scheme muddled; and the president takes on hunger.
U.S. investment in Burma remains modest, but Thai Gas Explorer PTTEP will invest $3.3 billion, while Burma's 'shrunken' population will deter international consumer business investment.
Kyaukphyu port on Burma's western coast could play a key role in a Beijing-led economic corridor plan linking neighbors India, Bangladesh and China.
Five airports get the green light for privatization, Kyaukphyu SEZ development to go out to tender, and the legacy of sanctions hinders US investment.
The Taiwan Electrical and Electronic Manufacturers' Association is reportedly planning a large investment to build an industrial park in the Irrawaddy Delta.
The new e-visa for tourists remains "cumbersome," an anti-money laundering watchdog is formed and natural gas imports are sought to meet a shortfall.


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Follow this item and we'll let you know when the price drops
Specifications & Dimensions
|Cutout Dimensions:
|See Installation Guide below product description
|Depth (In.):
|20 in.
|Duct Size:
|Standard 3-1/4 x 10 in.
|Filter Size:
|470 sq. in.
|Max. Height Above Cooktop:
|24 in.
|Maximum Width (In.):
|30 in.
|Min. Height Above Cooktop:
|18 in.
|Overall Width:
|30 in.
|Product Overview:
|Exhaust Method:
|Ducted & Ductless
|General Warranty:
|1 year parts and labor
|Color Family:
|Materials & Finishes:
|Grease Filter Material:
|Overall Material:
|Painted steel
|Control Type(s):
|Mechanical (dials/pushbuttons)
|Control(s) Location:
|Power Source:
|Seamless design with minimal edges and parts
|Hidden when not in use
|Clearance, above Cooktop:
|Dash for Compares & Unknowns
|Width, Opening:
|30 in.
|Ductwork Flexibility:
|4-way: rear, down, left or right
|Cooking light
|Light Type:
|Light Visibility:
|Recessed, visible only under hood
|Air Flow & Filtration:
|Air Mover Type(s):
|Internal centrifugal blower(s)
|Air Mover(s) Speed:
|2 speed
|Cubic Feet per Minute (CFM):
|Filter Cleaning:
|Grease Filter Style:
|Removable metal mesh
|Number of Air Movers:
|1 internal
|Sones (Noise Level) Rating:
|5.0 Sones
Ratings & Reviews
Product Description
Kenmore — trusted in the homes of more than 100 million Americans.
Contemporary-style range hood with sleek rocker controls for a clean appearance. Features a fully enclosed design and large, dishwasher-safe filters for easy cleaning. Dual halogen lights (sold separately) provide focused lighting as well as a soft, night-time level.
- Fully enclosed design for easy cleaning
- Dual halogen lamp design with two-level light setting (bulbs sold separately)
- Includes 3-1/4 x 10 in. duct connector with built-in damper and 7 in. duct connector
Added on October 21, 2010
Overall, others give this:
Reviewers may have received a benefit, like a sweepstakes entry or rewards program points, in exchange for writing a review.
Those benefits were not conditioned on the positive or negative content of the review.
Most Helpful Reviews
via sears.com
I shopped several websites looking for a range hood that I liked. When I saw this one online I went into my local Sears stores to see it in person. It was just what I wanted so I purchased it for my kitchen. I love it!
West Babylon, NY
via sears.com
removes odors quickly, n.ot too noisy
Danville, VA
via sears.com
Looks great, light is bright and fan isn't loud!
Oradell, NJ
via sears.com
After having a microwave with exhaust fan this is a nice change as it is quieter that the micro with fan and much stronger. The stainless is easy to clean and the filters are much larger than the ones on the microwave ovens with the fan.
Springfield, VA
via sears.com
Very powerful, and very sleek
Honolulu, HI
via sears.com
It was easy to install.
Los Angeles, CA
via sears.com
We love it. It looks beautiful in our kitchen.
Drexel Hill, PA
via sears.com
Bought to replace the aging and much greasy old one as we also bought our first double oven and this model was all that we need at a fair cost at our Sears store. Well liked and well built.
via sears.com
love the sleek design & the quietness of the fan!
Waveland, MS
via sears.com
It was easy to install. We just had to do a few tweaks; but, it works great. The light is just the right amount of brightness and the fan takes care of smoke and most odors.
- Members Get 10% back in points on first $500 of each qualifying purchase with a Sears Card. Offer ends 25-Dec-2014 See details.
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Best Price Photo
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BBB rating is based on 16 factors. Get the details about the factors considered.
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Customer Complaints Summary Read complaint details
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Climbing the Ladder
How Can I Write a Cover Letter That Will Help Me Stand Out?
I've just started my search for a new job, and I've found several companies that I'd really like to work for. How can I write a cover letter that will help me stand out amongst all the other applicants? — Stephanie, Virginia Beach, VA The thing...
Kick Up Your Negotiating Chops – at Work and at Home
I pride myself on being a savvy businessperson, career focused and ambitious, and yet I went 19 years without ever asking for a raise. I didn't think I needed to. Instead, I just worked very hard and hoped my boss would notice and reward me. My...
Why I'm Glad I Was Laid Off
Have you been canned in a company downsizing? Do you have your resignation letter ready to go, peppered with a top 10 list of "Things That Are Wrong With My Boss"? Or are you just so fed up with your underappreciated role in an unchallenging job...
Why Talking a Big Game Is Good for Your Career
When someone compliments you, is your automatic response anything like mine? "Really? I haven't slept in days. It must be the lighting in here!" Or, when you've been patted on the back for a job well done, do you allow your team to take credit...
10 Easy-to-Fix Cover Letter Mistakes
I have yet to meet a job hunter who doesn't dread writing cover letters. They're time-consuming and tedious, and unfortunately, they're unavoidable. It's easy to break cover letter etiquette if you're not careful. Those errors can cost you the...
What Do You Want From Your Next Job?
When you were fresh out of college, you might have taken any job that fit your major and paid enough to cover your share of the rent and student loan payment. But as you move through your career, your needs change in alignment with where you are...
Is There a Right Way to Fire Someone?
I recently became COO at my firm, which is exciting. But my job now includes HR, and my boss wants to fire an underperforming employee who has small children. I've never worked in HR before, and I'm really uncomfortable with this. What is the...
6 Tips For Politely Requesting a Job Referral
Whether you're unemployed or supported by a regular paycheck, job hunting and blindly sending out résumés can be a tiring and frustrating experience. So when the career gods smile in your direction and provide your dream position at a company...
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Adopt this fansite!
Posted On: Sep/13/14 | Posted By: ido | Category: Uncategorized
Do you love Hailee Steinfeld? If so then you should adopt this fansite from Free Fansite Hosting. Just ask!
Posted On: Jun/27/14 | Posted By: Laura | Category: Uncategorized
Hi guys i'm Laura. I am the brand new owner here at Hailee Steinfeld Source! I have one other Site on the web and its of the amazing Gracie Dzienny. To start off with i have given the site a brand new layout, as well as a gallery layout! Be sure to check them out as i love them! I have started to do a little updating with the gallery, i have added untagged photoshoot images of Hailee for Nylon Magazine. Make sure to check them out as she looks pretty as usual!
Met Ball 2014,Pitch Perfect 2 and more!
Posted On: May/28/14 | Posted By: HaileeFan | Category: Uncategorized
Hailee attended this year's Met Ball and was named "Best Dressed" by many magazines and fashion sites!
She also announced on twitter April 30th that she was to play a role in the Barden Bellas.She is now filming and recording for that.
Updates for both of these will be up soon!
NYLON magazine cover!
Posted On: Apr/29/14 | Posted By: HaileeFan | Category: Uncategorized
Hailee has a lot of things coming up for her!
She recently tweeted out her NYLON magazine cover!She has got some gorgeous photoshoot pictures and so I have updated the gallery here for you guys to see!
Hailee also attended the Hot Pink Party to raise awareness for Breast cancer.You can find pictures from the event here.
Hailee Steinfeld attends the 2014 Tribeca Film festival
Posted On: Apr/28/14 | Posted By: HaileeFan | Category: Uncategorized
Yesterday Hailee attended the premiere for "Begin Again"(previously known as Can a song save your life?) at the 13th annual tribeca Film festival.
She looked fabulous,as always and was accompanied by fellow co-stars,Keira Knightley and Adam Levine.
I have added some pictures to the gallery for you to see here.


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Hot answers tagged golden-calf-egel
Rashi is saying that in this instance they followed Moshe even though it didn't make sense. That is why the verse emphasizes that they did it - they did it despite the fact that it wasn't reasonable. They didn't always behave that way, in fact right afterwards (v. 11) in this very story.
Only top voted, non community-wiki answers of a minimum length are eligible


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Connecting the Dots: CNBC Exec's Children Murdered, 1 Day After CNBC Reports $43 Trillion Bankster LawsuitSubmitted by Freedom Ninja on Mon, 10/29/2012 - 16:46
By JG Vibes
October 27, 2012
This week financial news organization CNBC gave some mainstream attention to the largest money laundering and racketeering lawsuit in United States History, in which "Banksters" and their U.S. racketeering partners are being accused of laundering of 43 trillion dollars worth of ill gotten gains.
The lawsuit is said to involve officials located in the highest offices of government and the financial sector.
Since this information was surprisingly revealed by the mainstream news organization there has been a very suspicious and deadly fallout at the CNBC headquarters.
Within hours the original page for the article was taken down, and CNBC senior vice president Kevin Krim received news that his children were killed under very suspicious circumstances.
Read more:
- Login to post comments
Have there been any developments?
What is happening with this story, everything has gone quite? What's happening with the Fraud Case?
I'm just finding out about this
I can't believe I'm just now finding out about this. This is the biggest story of the century. Not a single mainstream outlet has reported it. The one outlet that does, the VP's children are killed the same day. A 50 year old thin nanny somehow stabs herself so forcefully it fractures her own vertebrae. Only 1.1% of women commit suicide by stabbing themselves, and I know of no case where they were able to fracture their own neckbone.
Has anyone else noticed...
Has anyone else noticed that all the "official" or "respectable" news outlets that are carrying this story seem to be missing the option to "share" the article via twitter, G+, facebook, or other social media?
WSJ's Market Watch has it up... no ability to share the story on social media.
Yahoo financial has it posted, no ability to share the story on social media, not even to your Yahoo wall, Y! or whatever it's called (if it is still around. Don't frequent Yahoo much anymore).
Am I missing the buttons to share (because I was gonna) or are they just not there? I mean I can share Yahoo financial as a whole on Facebook but not this particular article. Same with Market Watch.
Is that not....odd?
The article is no longer on Marketwatch.
Try here. http://investmentwatchblog.com/43-trillion-racketeering-laun...
Nanny is still alive and heavily sedated.
Is there anyone available to be able to get her side of the story?
Each one of us needs to decide if they wanna DIE NOW on their FEET or if they want to be part of the 90% that is exterminated later.
At least if you choose the former you've got a shot at living - IF WE ALL STAND UP NOW.
Visit the Mission Command Center & Join Our Ranks!
Still gotta research though.
If it's any consolation...
The children are in a much better place.
We're in hell right now. I for one am doing my best to establish God's Kingdom here on Earth... unfortunately due to the standard methods of operation that's not going to happen without casualties.
This Exec needs to re-post the article otherwise his children died for nothing.
Visit the Mission Command Center & Join Our Ranks!
I feel so sad for those
children and nanny.
Prepare & Share the Message of Freedom through Positive-Peaceful-Activism.
I knew it!
For Freedom!
The World is my country, all mankind is my brethren, to do good is my religion.
Here is the actual court complaint filed October 25, 2012.
Marina Krim found her children in a blood-soaked bathtub Thursday, Oct. 25.
It seems the father Kevin Krim, a CNBC digital media executive posted news of the filed court complaint against the government, banks, and the FED. He pulled the information he posted on Oct 25th, after the children were murdered.
There is probably some link and this may be a warning to the media to continue providing only government controlled propaganda to the public.
The ruling elite are no longer hidden from anyone. They stand naked in the eyes of the world, and no one is fooled any longer as to what is going on. They only HOPE they are still hidden. May justice be done, and may the spirit of integrity prevail in the world.
Here's my question...
...who commits suicide by slitting their own throat?
Kind of reminds of the folks who commit suicide by shooting themselves in the back of the head, chopping themselves into little pieces, stuffing the pieces in black garbage bags, placing these in the trunk of their car, and then closing the trunk.
"Alas! I believe in the virtue of birds. And it only takes a feather for me to die laughing."
Someone else did it or she
Someone else did it or she was compensated to make it appear like a murder suicide?
And Hurricane Sandy takes "unexpected" turn towards NY
Making sure she takes up all the headlines in NY and not the $43 Trillion Lawsuit. I think she's in on it.
"We are not human beings having a spiritual experience; we are spiritual beings having a human experience"—Pierre Teilhard de Chardin


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Updated for 2014! Weighing just over a pound and featuring premium 875+ fill power goose down insulation, the high-performance Marmot Plasma 40 Degree down sleeping bag is ideal for warm weather backpacking.
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Streamlined designs, with lightweight fabrics and fill make these the lightest offerings available
View more videos in our Video Library.


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Real Estate Sales & Broker
Found 20 product(s) for Real Estate Sales & Broker (1-20 of 20)
National Learning Corporation Passbooks-Online is proud to offer a Companion PDF to many of our testing study guides, containing all of the practice questions and answers found in the physical book, enabling professionals and students to review testing materials on a variety of digital devices including laptop computers, tablets, and ebook reading devices. The companion will enable users to output question sets or answer keys to assist in the study process or simple review all materials electronically. Practice questions are mobile making it easy to study and review whenever time permits.
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About Houston Cinema Arts Society
Houston Cinema Arts Society is a 501 (c) (3) nonprofit organization dedicated to presenting innovative films, media installations, and performances that celebrate the artistic process and enrich Houston's culture and urban vitality.
Stories About the Society
HCAS is a non-profit in the running
In just six years, Houston Cinema Arts Society (HCAS) has put the nation's fourth largest city on the map among film industry professionals, artists, and film aficionados as a premier showcase for the moving image and the creative process.
HCAS Executive Director Trish Rigdon on Channel 2
Check out this interview of HCAS Executive Director Trish Rigdon telling you about Julydoscope 2014
Breaking News
Twitter Feed
CinemArtSociety @CinemArtSociety
Attend a special holiday screening of MIRACLE ON 34th STREET at Landmark River Oaks on Tuesday, December 2nd at... http://t.co/Chh4lnOU1n
CinemArtSociety @CinemArtSociety
Here are the highlights from day 5 of the festival. Enjoy! http://t.co/DwerauAcPO


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Vacuum Cleaner Bags
Vacuum cleaning systems that offer the best cleaning ability – is that what you are seeking? It's also likely that you believe that cleaning ability is related to power or suction. Actually, it's not. While there's no single factor that determines the cleaning ability of the vacuum cleaner you use, understanding how vacuums work and how you can help maintain your vacuum cleaner to perform its best is important. Changing your vacuum cleaner bag is an important step in maintaining the efficiency of your vacuum cleaner. While most vacuum cleaners come with an indicator to help you determine when your cleaner's dust bag needs to be changed, you can perform a check yourself to see if it is over 50% full as that's when you need to replace it. Don't wait until the dust bag in your vacuum cleaner is completely full as it can reduce the suction and cleaning capacity of your vacuum cleaning system. If you use your vacuum cleaner frequently, it is recommended that you change vacuum cleaner bags once a month, especially if you are cleaning a large area over 2000 square feet or if your pet sheds a lot.
What you need the most when you are considering vacuum cleaner bag replacement is a bag that is well-matched with the model of your vacuum cleaning system. You can find original equipment manufacturer (OEM) or replacement type bags online. While both serve the purpose, that is enhancing the cleaning capacity of your vacuum cleaning system and providing you an easy way to get rid of all the dirt that you vacuum cleaner collects, you can choose one according to your budget and cleaning needs. At GoVacuum, we have got a vast range of vacuum cleaner bags from the biggest and the best brands around. You'll find them here at great prices and shipping offers. We are the vacuum cleaning system experts and can recommend the right bag for your existing system all while staying within your budget.
Vapamore Storage Bag- Replacement for Model MR-100Vapamore MR-100 is a versatile and multipurpose vapor steam cleaner that harnesses steam to thoroughly clean and disinfect all areas in home and office. The highlight of this high performance product is that corrosive and harmful chemicals and detergents are not needed. Users of this machine will be able to reach previously inaccessible nooks and corners. It completely gets rid of germs and allergens which cause many ailments including allergy and asthma. This state-of-the-art cleaning machine is specifically designed to be easy and simple to use. It comes along with specially designed attachments and accessories to meet the many different cleaning needs of homes and offices. It is aesthetically designed and compact. It's a one of a kind environment friendly and complete cleaning solution. Why go for other storage bags when the best quality Vapamore storage bag is there to fulfill the complete spectrum of cleaning needs. You can buy this storage bag at Govacuum.com, a one stop portal for all your cleaning solutions and systems. This site offers a variety of products from the best of companies and facilitates superior customer service. Enjoy a convenient and classy shopping experience designed to give complete satisfaction in terms of quality and versatility. Product Features •Vapamore Storage Bag - Replacement for Model MR-100 •Fits all Vapamore Primo steam cleaners Learn More
Sanyo Cannister Type SC-P7 [3 Bags per pack]Sanyo Cannister Type SC-P7 [3 Bags per pack] Learn More
Sanyo SC-PU1 Vacuum Bags [3 pack]Sanyo Upright Model SC-PU1 [3 Bags per pack] Learn More
Sanyo SC-P8A 5 Pack Vacuum Cleaner BagsSanyo SC-P8A 5 Pack Vacuum Cleaner Bags. Part Number SC-P8A Learn More
Generic Sanyo Upright Bag Generic Allergen 3 PackSanyo upright bags fit units with on-board tools and all models beginning with SC-A or SC-U. Each package contains 3 generic allergen bags. Learn More
Sanyo Type P11, SC-P11 Transformax Vacuum Cleaner Bags Transformax Vacuum Cleaner Bags P-11Works With: Sanyo P11 Sanyo SC-P11 Sanyo Transformax Description:10 Genuine Sanyo Bags In Pack Learn More
Sanyo Canister Type SC-P7 Bags +This Sanyo Canister Type SC-P7 Bags comes in a Pack of 3. Learn More
Sanyo SC-PU110 Upright Bags -10 packQuantity Per Package: 10 Sanyo vacuum bags OEM Part Number: SC-PU110 Learn More
Euro-Pro Shark EP704/704H/SHF Bags 9 PK.Genuine Euro-Pro Shark Upright Vacuum Cleaner Bags for the Spectra and Widepath upright models. Each package of bags comes with 9 bags. Fits Shark models; EP704, EP704SH, EP705, EP821, EP825, UV180, and UV204. Genuine Shark part number XSG704. Learn More
Generic Shark Widepath Upright 10 pack Micro Filtration bagsGeneric Shark Widepath Upright 10 pack Micro Filtration bags Learn More
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