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A new study sets the stage for wider use of gene testing in early pregnancy. Scanning the genes of a fetus reveals far more about potential health risks than current prenatal testing does, say researchers who compared both methods in thousands of pregnancies nationwide.
A surprisingly high number — 6 percent — of certain fetuses declared normal by conventional testing were found to have genetic abnormalities by gene scans, the study found. The gene flaws can cause anything from minor defects such as a club foot to more serious ones such as mental retardation, heart problems and fatal diseases.
"This isn't done just so people can terminate pregnancies," because many choose to continue them even if a problem is found, said Dr. Ronald Wapner, reproductive genetics chief at Columbia University Medical Center in New York. "We're better able to give lots and lots of women more information about what's causing the problem and what the prognosis is and what special care their child might need."
He led the federally funded study, published in Thursday's New England Journal of Medicine.
A second study in the journal found that gene testing could reveal the cause of most stillbirths, many of which remain a mystery now. That gives key information to couples agonizing over whether to try again.
The prenatal study of 4,400 women has long been awaited in the field, and could make gene testing a standard of care in cases where initial screening with an ultrasound exam suggests a structural defect in how the baby is developing, said Dr. Susan Klugman, director of reproductive genetics at New York's Montefiore Medical Center, which enrolled 300 women into the study.
"We can never guarantee the perfect baby but if they want everything done, this is a test that can tell a lot more," she said.
Many pregnant women are offered screening with an ultrasound exam or a blood test that can flag some common abnormalities such as Down syndrome, but these are not conclusive.
The next step is diagnostic testing on cells from the fetus obtained through amniocentesis, which is like a needle biopsy through the belly, or chorionic villus sampling, which snips a bit of the placenta. Doctors look at the sample under a microscope for breaks or extra copies of chromosomes that cause a dozen or so abnormalities.
The new study compared this eyeball method to scanning with gene chips that can spot hundreds of abnormalities and far smaller defects than what can be seen with a microscope. This costs $1,200 to $1,800 versus $600 to $1,000 for the visual exam.
In the study, both methods were used on fetal samples from 4,400 women around the country. Half of the moms were at higher risk because they were over 35. One-fifth had screening tests suggesting Down syndrome. One-fourth had ultrasounds suggesting structural abnormalities. Others sought screening for other reasons.
"Some did it for anxiety — they just wanted more information about their child," Wapner said.
Of women whose ultrasounds showed a possible structural defect but whose fetuses were called normal by the visual chromosome exam, gene testing found problems in 6 percent — one out of 17.
"That's a lot. That's huge," Klugman said.
Gene tests also found abnormalities in nearly 2 percent of cases where the mom was older or ultrasounds suggested a problem other than a structural defect.
Dr. Lorraine Dugoff, a University of Pennsylvania high-risk pregnancy specialist, wrote in an editorial in the journal that gene testing should become the standard of care when a structural problem is suggested by ultrasound. But its value may be incremental in other cases and offset by the 1.5 percent of cases where a gene abnormality of unknown significance is found.
In those cases, "a lot of couples might not be happy that they ordered that test" because it can't give a clear answer, she said.
Ana Zeletz, a former pediatric nurse from Hoboken, N.J., had one of those results during the study. An ultrasound suggested possible Down syndrome; gene testing ruled that out but showed an abnormality that could indicate kidney problems — or nothing.
"They give you this list of all the things that could possibly be wrong," Zeletz said. Her daughter, Jillian, now 2, had some urinary and kidney abnormalities that seem to have resolved, and has low muscle tone that caused her to start walking later than usual.
"I am very glad about it," she said of the testing, because she knows to watch her daughter for possible complications like gout. Without the testing, "we wouldn't know anything, we wouldn't know to watch for things that might come up," she said.
The other study involved 532 stillbirths — deaths of a fetus in the womb before delivery. Gene testing revealed the cause in 87 percent of cases versus 70 percent of cases analyzed by the visual chromosome inspection method. It also gave more information on specific genetic abnormalities that couples could use to estimate the odds that future pregnancies would bring those risks.
The study was led by Dr. Uma Reddy of the National Institute of Child Health and Human Development.
Read more: Medical journal at http://www.nejm.org
Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP
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David Hammond
Twitter: DineOakPark
David Hammond, a corporate communications consultant and food journalist living in Oak Park, Illinois, is a founder and moderator of LTHForum.com, the 8,500 member Chicago-based culinary chat site. David is a regular contributor of restaurant reviews and food-related articles for Chicago Tribune, Chicago Sun-Times, TimeOut Chicago, Local Beet, and Chicago Reader, which published his seven-part guide to regional Mexican food in the city. He has also contributed food writing to blogs such as the Local Beet and Grubstreet Chicago. With his friend Michael Gebert (creator of Sky Full of Bacon video podcasts), he hosted a cable documentary on Hispanic chow at Chicago's Maxwell Street Market,and has just completed working on a video about Taste of Melrose Park. A returning guest on WLS and WGN AM radio, David produces the "Soundbites" series on the James Beard-nominated Eight Forty-Eight (Chicago Public Radio, WBEZ, 91.5FM); these radio pieces examine how Chicago chefs use sound in their kitchens; listen here: http://tiny.cc/QpCTA. David was featured on "Good Morning, America," "Chicago, Tonight," and Nippon TV when he developed recipes for preparing seasonal cicadas, which invaded Chicagoland during the spring of 2007. More information, including writing samples and bug-cooking videos, can be found at www.dchammond.com.
Latest News Articles
Wurst is best at Carnivore
Carnivore opened late last summer, and we've been there a few times to pick up meat and fish. The boys at Carnivore now also offer lunch. Stopping in for a sandwich is a good way to sample their hand-crafted wurst.
A backyard full of fish and plants
Saturday, July 27, was the second annual Edible Garden Tour sponsored by the Sugar Beet Co-op, which officially launched last February.
Why not food carts instead of trucks?
In Oak Park last spring, we had a food truck rally that can only be described as a "disappointing success." This parking lot-based (Pilgrim Church) gathering of food trucks generated a huge turnout of villagers — so much so that some vendors ran out of supplies within the first 30 minutes and many more within the first hour.
Eating our way through southeast Asia: A cruise to celebrate 30 years... and to eat
I met my wife, Carolyn Berg at Kalamazoo College in Michigan. We both chose this small, liberal arts school largely because of its foreign study program. To celebrate our 30th wedding anniversary, we booked passage on the Zaandam, a ship in the Holland America Line. This 14-day cruise docked at a number of ports in Southeast Asia, including Singapore, Thailand, Cambodia, Vietnam, China and Hong Kong.
Latest Blogs
Pastrami and Chopped Liver at Onion Roll
Why in the world doesn't the Onion Roll serve a good onion roll? My heart sank when my lunch arrived: the pastrami and chopped liver looked fantastic, and the fries were perfectly crisped, but the onion roll…oy.
Cubano at 7 Sandwich
What elevates the Cubano is the plancha, a clam-shell type grill that presses warm metal against both sides of the sandwich and makes it so much more than just a ham n' cheese.
I Drink from Johnny's Mug
At the Elkhorn Valley Museum, there are a number of Carson artifacts, and it was there that I picked up mug that was, I was told, actually used by Carson on the tonight show.
Secret BYOB at Oak Park Restaurants
Both Jerusalem Café and Luo's Peking House let you bring a bottle to dinner, but this BYOB policy is unadvertised. Perhaps the reluctance to advertise the BYOB policy reflects a temperate sensibility that goes back to Oak Park's dry days.
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Anyone familiar with the New Haven project will confirm it is more like a prototype for 21st century living than a building. 360 State is such a perfect embodiment of the ultimate dream design that it even attracted the attention of Senator Chris Dodd (D-CT). He made a site visit in March 2010 while promoting S.1619 (the Livable Communities Act of 2009), a measure he introduced to the Senate in August of 2009. This bill, currently curdling in the 23-member Senate Committee on Banking, Housing and Urban Affairs, would provide a variety of grants totalling $400 million to assist in the development of sustainable communities. Dodd's photo op at the project helped burnish 360's new brand as a deep green example of the types of innovative and sustainable projects S.1619 could support.
Project developer, Bruce Becker (pictured at right), likes to point out that in addition to the fuel cell, the building uses 34 energy saving technologies. For example, the Climate Master TS-series heat pumps used in the building are the highest efficiency pumps on the market today. The result speaks for itself. When benchmarked against a comparable, code-compliant building of similar proportions, 360 State will have half the carbon footprint.
Butlers might as well queue up now in the unemployment line, as the complex will also provide a concierge service along with cookies and coffee in the lobby. The developer will also support the arts through exhibits in the lobby of original artwork by both local and national artists. The building facade, by the way, has been embellished by renowned Yale School of Architecture ornament professor, Kent Bloomer. The complex is stunning and glamorous, but it is its sustainability features that really dazzle. Once in a while in life, residents really can have it all.
Green Landlady asked Lenox if there is a plan to include urban agriculture in the mix - the green roof is already part of the design - and Lenox's answer was pretty upbeat.
When GreenLandlady pointedly asked about leasing results, there was no pushback. Lenox remained enthusiastic and forthcoming about their progress, obviously an easier posture when the results are all great. Like most leasing agents – green building represents only about 3% of the entire U.S. building stock nationwide - Lenox had no previous experience leasing sustainable units. However, she spoke with the zeal of an evangelist when she offered her views:
There is no reason to doubt Lenox, as the low vacancy factor is the result of a long-standing inadequate supply and lack of new apartment building in New Haven. Certainly people are interested in 360 State Street, so we asked the big question. Are they willing to pay for it? Lenox answered in the affirmative.
"Most people in New Haven are not going to move to live in 360 State Street, but most of them will use the grocery store," he said. "It's more relevant to the general population."
The Connecticut Clean Energy Fund provided a grant to fund half the cost of 360 State Street's 400 Kilowatt fuel cell stack. This grant will make it possible to reach the breakeven point (from energy savings) in about 5.5 years. The fuel cell will generate most of the building's power needs in addition to providing space heating, cooling, conditioning and the building's hot water. The fuel cell system is the largest residential installation of this type of technology anywhere in the world.
As tenants learn to appreciate the benefits of high efficiency lighting, energy star appliances, thermal comfort, occupancy sensors in common areas, excellent environmental air quality and the other benefits of a deep green building, they may also experience better health. Although this all sounds and is very luxurious, the building guarantees that 10% of the units will be leased to those who qualify for affordable housing.


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Infrastructure Project Manager
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NEXTEP Technology Solutions is seeking an experienced Sr. SAP Time Management Consultant for our client located in St. Louis, MO. This is a CONTRACT position with an expected duration of 6-12+ months.
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Work on continued rollout of SAP Time Management for our ...
Master Data Management Analyst
Position: Master Data Management Analyst
Requisition: JTL7975
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Pay Rate: $41.10 - $47.95 +OT
Term: 6 Month Contract
Experience: 3-5 years' product data experience preferred in an e-Commerce environment supporting data related initiatives, ...
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Our client is currently seeking a Program Manager. The Program Manager will be responsible for overseeing and managing cross-functional areas of product development via program team structures. This position serves an essential liaison role between the program team and ...
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Technical Projects Manager
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ADB Companies, Inc. has an opportunity available for a Technical Projects Manager to support our Professional Services team located in St. Louis, MO. A minimum of five years' experience in a Professional Services environment, leading or working in a ...
Director of Health Information Management (HIM)
The HIM Director is responsible for leading and directing coding, training, reporting, and reimbursement services across the healthcare delivery system striving for compliance and best practices. Has the administrative ...
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Technology Management Auditor
We are a supply chain management consulting company. Our services cover all aspects of supply chain management, logistics and business analytics; from the strategies all the way through to successful implementations. Our supply chain consultants are very experienced in ...
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Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel
This study is currently recruiting participants. (see Contacts and Locations)
Verified May 2013 by Soricimed Biopharma Inc
Soricimed Biopharma Inc
Information provided by (Responsible Party):
Soricimed Biopharma Inc
ClinicalTrials.gov Identifier:
First received: April 13, 2012
Last updated: May 29, 2013
Last verified: May 2013
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to determine the safety and tolerability of the drug SOR-C13 when given as an intravenous infusion in patients with ovarian cancer or other cancers known to over express the TRPV6 calcium channel.
Drug: SOR-C13
Phase 1
|Study Type:
|Study Design:
|Endpoint Classification: Safety Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|Phase I, Open-label, Dose Escalation Study to Assess Safety and Tolerability of SOR-C13 in Subjects With Advanced Solid Tumors Commonly Known to Express the TRPV6 Ion Channel
Resource links provided by NLM:
MedlinePlus related topics: CancerU.S. FDA Resources
Further study details as provided by Soricimed Biopharma Inc:
Primary Outcome Measures:
- Toxicity graded according to the National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0 [ Time Frame: Over 21 days from initial administration ] [ Designated as safety issue: Yes ]
Secondary Outcome Measures:
- Plasma levels of SOR-C13 [ Time Frame: Pre-treatment and up to 4 hours post-treatment on Study Days 1, 3 and 10 ] [ Designated as safety issue: No ]
|Estimated Enrollment:
|Study Start Date:
|July 2012
|Estimated Primary Completion Date:
|March 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: SOR-C13
Drug: SOR-C13
Intravenous solution for infusion, potential dose range 5.5 mg/kg to 44 mg/kg, dosing frequency 2 cycles with a cycle consisting of infusions on days 1-3 and days 8-10 followed by a 11 day off period
|Ages Eligible for Study:
|18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion criteria
- Males and females ≥ 18 years of age
- Subjects with a histologic diagnosis of solid tumor cancers of epithelial origin.
- Subjects with advanced refractory cancer for which standard curative or palliative measures do not exist or are no longer effective. There is no limitation on the number or types of prior therapy.
- Subjects must have recovered from major infections and/or surgical procedures and, in the opinion of the investigator, not have a significant active concurrent medical illness precluding protocol treatment.
- ECOG (Eastern Cooperative Oncology Group) Performance Score ≤ 1.
- Life expectancy of greater than 12 weeks.
Subjects must have adequate organ and marrow function as defined below:
- hemoglobin ≥9.0 g/dL (≥5.6 mmol/L)
- white blood cells ≥3,000/mm³(≥3×10⁹/L)
- absolute neutrophil count ≥1,500/mm³ (≥1.5×10⁹/L)
- platelets ≥100,000/μL (≥100×10⁹/L)
- total bilirubin ≤1.5× upper limit of normal(ULN)
- creatinine ≤1.5× ULN
- albumin ≥3.0 g/dL (≥30 g/L)
- Ability to understand and voluntarily sign the informed consent document
Exclusion Criteria:
- Chemotherapy, immunotherapy, radiotherapy, biologic or any investigational therapy will not be allowed within either 30 days, or 5 half lives (whichever is longer) prior to study drug administration.
- History or clinical evidence of central nervous system (CNS) tumor involvement (metastases) or other known clinically relevant CNS pathology (e.g., epilepsy, seizure, paresis, aphasia, cerebellar disease, severe brain injury, psychosis).
- Concurrent malignancy other than the solid tumor under investigation, requiring active treatment.
- History of clinically significant allergic reaction attributed to any injected compound.
- History of any of the following cardiovascular events or conditions within the past 6 months prior to enrolment: myocardial infarction, unstable angina, cerebrovascular accident or transient ischemic attack, New York Heart Association Class ≥ II chronic heart failure, hypokalemia, significant arrhythmia*; QTc interval >430 msec or use of drugs that prolong the QT interval at screening; family history of long QT syndrome.(* Significant arrhythmias are defined as symptoms of syncope or severe palpitations (palpitations requiring referral to cardiac monitoring), or ECG findings of supraventricular tachycardia (including ventricular fibrillation) or ventricular ectopy (ventricular premature depolarization).
- Clinically significant and uncontrolled major medical condition(s) that places the subject at an unacceptably high risk for toxicities. These include, but are not limited to: active infections, symptomatic pulmonary disease, inadequate pulmonary function, seizure disorder, psychiatric illness.
- Current use of more than one antihypertensive medication.
- For patients receiving antihypertensive medication:systolic blood pressure < 120 mmHg and/or diastolic blood pressure < 70 mmHg at screening.
- A known diagnosis of human immunodeficiency virus (HIV) infection or acquired immune deficiency syndrome (AIDS), acute or chronic hepatitis B or hepatitis C infection, as determined by medical history.
- Major surgical procedure within 4 weeks prior to enrolment.
- Lactating or pregnant female.
- Females of childbearing potential and males not using adequate birth control.
- Current treatment or treatment within 4 weeks of screening with bisphosphonates.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01578564
Please refer to this study by its ClinicalTrials.gov identifier: NCT01578564
|Contact: Nicholas G Fields, PhD
|Contact: Toney T Ilenchuk, MS, Ph.D.
|United States, Texas
|MD Anderson Cancer Center
|Houston, Texas, United States, 77230-1402
|Contact: Siqing Fu, MD, PhD
|Principal Investigator: Siqing Fu, MD, PhD
|Canada, Ontario
|Juravinski Cancer Center
|Hamilton, Ontario, Canada, L8V 5C2
|Contact: Hal W Hirte, MD 905 387 9495 ext 64603
|Principal Investigator: Hal W Hirte, MD
|London Health Sciences Centre
|London, Ontario, Canada, N6A 4L6
|Contact: Stephen Welch, MD
|Principal Investigator: Stephen Welch, MD
Sponsors and Collaborators
Soricimed Biopharma Inc
|Study Director:
|Toney T Ilenchuk, MS, PhD
|Soricimed Biopharma Inc
More Information
No publications provided
Keywords provided by Soricimed Biopharma Inc:
ClinicalTrials.gov processed this record on November 25, 2014
No publications provided
|Responsible Party:
|Soricimed Biopharma Inc
|ClinicalTrials.gov Identifier:
|NCT01578564 History of Changes
|Other Study ID Numbers:
|Study First Received:
|April 13, 2012
|Last Updated:
|May 29, 2013
|Health Authority:
|United States: Food and Drug Administration
Canada: Health Canada
Keywords provided by Soricimed Biopharma Inc:
Ovarian Cancer
TRPV6 Calcium channel
ClinicalTrials.gov processed this record on November 25, 2014


text:
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The last time Sri Lanka played a Test in Hobart, they nearly pulled off an impossible heist. Kumar Sangakkara looks back at his epic innings there
Interview by Andrew Fernando
December 11, 2012
Sri Lanka's last Test tour to Australia, in 2007, returned a 2-0 loss, but the final innings of the series produced the best Test performance by a Sri Lankan in Australia. As the team return to Hobart in 2012, Kumar Sangakkara's 192 there will be a source of fond memories not only for the man himself, but for fans, who have not seen a fight as fierce from a Sri Lankan on Australian soil.
Related Links
Report : Australia win despite Sangakkara's 192
Analysis : Unrewarded brilliance
Players/Officials: Kumar Sangakkara
Matches: Australia v Sri Lanka at Hobart
Series/Tournaments: Sri Lanka tour of Australia
Teams: Sri Lanka
Sangakkara's tour began poorly, when he was injured after just three balls in Sri Lanka's first tour match, in Adelaide.
I was more worried about not being able to play a Test match rather than adjusting to Australian conditions, but that time off was useful. I strained my hamstring and was out for about 17 days, but that time was used to recover and also to bat a lot in the side nets and hit a lot of throwdowns with Trevor Bayliss. I faced a lot of net bowling with Lasith Malinga and with the bowling machine. Those days were spent working really hard with a view to getting ready for the second Test. The selectors and the staff had a chat and they thought it was worth the risk of keeping me on.
In the first Test, in Brisbane, Sri Lanka stumbled to an innings-and-40-run loss. In Sangakkara's absence only two Sri Lanka batsmen got past 50 on a pitch on which three Australia batsmen hit hundreds.
The Australians played really well in that game and outplayed us completely, and the wicket didn't offer any help to our spin attack, which was our strength at the time. Lasith Malinga didn't play in that Test match either. It was not pleasant sitting on the sidelines, but it was also more motivation to get ready for the next Test match.
We had resigned ourselves to the fact that we didn't play well in the first Test, and tried to up our standards in the second. It was just a case of learning and preparing again for a big challenge in Hobart.
Australia won the toss and amassed 542 for 5 declared in Hobart, with centuries to Phil Jaques and Michael Hussey. Sangakkara's first-innings 57 came from 76 balls and had its moments of fortune, including being dropped by Adam Gilchrist on 13.
I was a bit rusty to start off with. I had to get my feet going and get used to facing good bowlers consistently. In those conditions, you need a bit of luck to go your way. I got a 60 and managed to hit one to gully when I was really backing myself and getting into a good rhythm.
I hit Mitchell Johnson to Michael Hussey. That was not pleasant because I knew I had had a bit of good fortune to get there and then it was really up to me to try and kick on further. Thankfully Mahela [Jayawardene] got a century in that first innings and got us to an okay total.
Sangakkara took mental notes from his time at the crease in the first innings, observing both the bowlers' strengths and the nature of the surface, filing the information away for the second dig.
Johnson and [Brett] Lee had swing early on and pace right throughout, whereas Stuart Clark was more medium pace and movement off the seam. It was a case of getting used to what they were bowling and backing myself to get behind the ball.
You had to make sure that, when you drove, you were right on the ball. Your head's got to be right over it and your foot's got to be right there, because with that bounce, even if you were slightly off the ball there was always the chance the ball would carry to the slips.
|"That was a special day for me. Everything clicked and worked. It was very easy for me to hit those shots because I was in the zone - in that space where everything goes right"
Rather than playing on the front foot, it was a case of making sure I cut and pulled well and looked for the right ball to drive.
Sri Lanka were dismissed for 246 in the first innings, but Australia chose to bat again, and piled on a further 210, setting Sri Lanka 507 to win in just over five sessions.
When we went out to bat a second time I don't think anyone thought of anything too far ahead, in terms of winning or batting for a draw. It was a case of getting through, session by session and getting as close as possible. There was never a conscious idea of "We are going to bat x amount of time", because that's difficult to do. Rather: get going, assess, and continue that way.
Sri Lanka began positively, getting to 100 in the 26th over. Marvan Atapattu was playing his final international innings, and Sangakkara was alongside him for much of day four, having come in at 15 for 1, and they played out a full afternoon session together.
You have to be positive against an attack like that. They had attacking fields all the time and had a lot of bowling options, so if you are positive and you get away with that, it sets you up to really dominate an innings.
The chase was a steep one - we would have had to achieve the biggest fourth innings total ever to win a match, and it would have been very easy to fall into the trap of shutting down the scoring. But we actively looked to score runs whenever we could.
When we were about 150 for 1, batting with Marvan, it was just a question of getting through that final spell of Brett Lee's, because he was bowling well. We wanted to be 220 for 1 at the end of the day, to have a realistic chance of chasing down the total. But unfortunately Marvan got out in what was probably Lee's last over, and then Mahela got out soon after, first ball. That really set us back.
Sanath Jayasuriya came in at No. 5 and began to attack. His belligerence sparked aggression from Sangakkara as well. The pair scored at more than five an over for the first 15 overs of their partnership and finished the day at 247 for 3 - 260 more runs needed to win on the final day.
It definitely makes things easier when someone is scoring quickly at the other end, and I think that partnership with Sanath set me up for that final day. I got to 100 before stumps, and while it would have been better to not have lost those two quick wickets in that session, I felt I was batting well and we weren't in the worst position.
Early on the fifth morning Jayasuriya departed for 45, and two wickets fell off consecutive balls soon after. Sangakkara was left in the company of the tail and Australia with little to do to achieve a series whitewash.
When the second new ball came around, Sanath got out and we let two quick wickets fall. It was a big setback to see those guys get out off consecutive balls, and Prasanna [Jayawardene] offering no stroke to Mitchell Johnson.
It was just a case of trying to set a base, but unfortunately we lost too many wickets. I just had to do what I had to do. I couldn't control what happened at the other end, but I could control my end.
I had tried to retrain my eyes and feet on the fifth morning, giving myself the best chance of really making a big score, but I had to change that approach. When I was batting with Farveez Maharoof and Lasith, we just tried to get as many runs as quickly as possible. It helped that the wicket had flattened out. The bowlers were still bowling well, but they had to really work hard.
I tried to be a lot more attacking and farm the strike as much as possible and try and hit as many boundaries as possible, because they had pretty attacking fields. If the field was up, I'd go for boundaries, and when the field was down, I'd try to get down the other end on the fifth ball.
Sangakkara backed away to smite Mitchell Johnson over cover for six, to surpass Aravinda de Silva's 167 in 1989, which had been the highest innings score by a Sri Lankan in Australia.
It was probably Stuart MacGill that I wanted to take as many runs from as possible. He wasn't bowling that well. He had had a few injuries and was coming back from that and wasn't bowling as well as he usually did. My target was to dominate him.
I tried to give a little more respect to the whole pace attack. They were bowling really well as a unit and I had to play them on merit, but because I was in really good touch I managed to hit some boundaries off them as well.
My feet were moving well and I was getting behind the ball nicely. It was a case of having batted a full day before and having become used to the pitch and the Australian bowling, and I had played myself into form.
Sangakkara's use of the lofted cover drive off the pacemen was striking, and the shot brought him several boundaries on the final day. His glides through point and behind gully were also productive.
You have good days and bad days, and then some days when you are able to do things that you normally can't. That was a special day for me. Everything clicked and worked. It was very easy for me to hit those shots because I was in the zone - in that space where everything goes right. Lasith was holding up one end as best as he could and that gave me the freedom to attack from the other.
I think in the end we got closer to their total than we thought we would.
Sangakkara was moving swiftly towards a double-century when he was wrongly given out on 192. He had made a double-hundred in each of his previous matches, and was on course to become the first player in history to make double-hundreds in three consecutive matches.
I think you do definitely look at personal milestones like that, and I was targeting 200. The ball that got me out was a bouncer and I was a bit too quick on it, and I was through the hook shot when the ball got to me. When the finger went up I was very disappointed and there was a bit of anger. But what can you do when you get given out like that? I just trudged off and it took me a little while to cool down.
Rudi Koertzen, who had given the decision, apologised to Sangakkara after learning he had been wrong.
It was easy to accept his apology. It was very nice of him to come and talk to me at the end of the day. I respected him as an umpire because he was a very good umpire. It was just a mistake, and these things happen at either end.
Sri Lanka were eventually all out for 410, 97 short of victory. It was, and remains, their highest fourth-innings total.
I guess you're left wondering about what could have happened if I could have kept going, but that was definitely one of my best innings. Under pressure, against an attack like that, I rate it very highly.
Andrew Fernando is ESPNcricinfo's Sri Lanka correspondentFeeds: Andrew Fidel Fernando
© ESPN Sports Media Ltd.
|Comments have now been closed for this article
'Everyone stares at you when you're 6ft 8in'
Boyd Rankin talks about giants, playing for the enemy, and being mentored by Allan Donald
Bravo's withdrawal highlights cricket's stress malaise
Tony Cozier: He and Kieran Powell should follow Lara's example by seeking professional help to resurrect their promising careers
Four afternoons into immortality
Rewind: In 1899 a 13-year-old orphan at Clifton College established a world record which stands to this day
David Hopps: In England, changes in social attitudes, the demands of work, and other factors are contributing to a decline in recreational cricket
The multifaceted Mr Ravi Shastri
Stuart Wark: We might know him better as a commentator, but in his day he was a fine spinner and, when called on, a gritty opener
Pakistan should not welcome Amir back
The serene team culture cultivated by Misbah and his men shouldn't be allowed to be disrupted by a player with a tainted past
Contrite Kohli, apoplectic Kohli, and a Dhoni impersonator
Plays of the day from the fifth ODI in Ranchi
'I don't blame Arjuna for my early retirement'
Former Sri Lanka batsman Asanka Gurusinha talks about playing and coaching in Australia, and tactics during the 1996 World Cup
Dhoni's absence a guide to India's future
He's past his use-by date as a Test captain and keeper. India now have a chance to test Kohli's leadership skills
'I'm a bit disappointed not to get that Test average up to 50'
Mahela Jayawardene reflects on his Test career, and the need to bridge the gap between international and club cricket in Sri Lanka
Pakistan should not welcome Amir back (180)
The serene team culture cultivated by Misbah and his men shouldn't be allowed to be disrupted by a player with a tainted past
Dhoni's absence a guide to India's future (72)
He's past his use-by date as a Test captain and keeper. India now have a chance to test Kohli's leadership skills
'I'm a bit disappointed not to get that Test average up to 50' (56)
Mahela Jayawardene reflects on his Test career, and the need to bridge the gap between international and club cricket in Sri Lanka
A crisis that defines the age (36)
Never mind cricket's absence from free-to-air TV - changes in social attitudes, the demands of work, and an individualistic age are all contributing to a decline in participation
Pujara and the challenge of being a Test-only batsman (34)
Shorter tours don't allow you time to get into form, and domestic cricket isn't demanding enough


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"I promise you: No American whose great-grandfather was born here is watching soccer," Coulter says
The U.S. just advanced to the next round of the World Cup, but Ann Coulter is unimpressed with soccer. In a column for her website titled "America's Favorite National Pastime: Hating Soccer," she argues that the internationally beloved sport is inherently antithetical to her country's system of values.
The conservative pundit compiled a list of reasons why hating the internationally beloved sport is not only a natural reaction to frequent low scores but also emblematic of liberal values she abhors.
Also read: Soccer Star Hope Solo Arrested for Alleged Domestic Violence
"Individual achievement is not a big factor in soccer. In a real sport, players fumble passes, throw bricks and drop fly balls — all in front of a crowd," Coulter said.
"In soccer, the blame is dispersed and almost no one scores anyway. There are no heroes, no losers, no accountability, and no child's fragile self-esteem is bruised. There's a reason perpetually alarmed women are called 'soccer moms," not "football moms.'"
Coulter faced heavy scrutiny after mocking first lady Michelle Obama's heartfelt Twitter plea to "#BringBackOurGirls" from Nigeria, but that didn't stop her from going after another of the left's leading lady in her anti-soccer column.
See photos: Soccer Phenom Cristiano Ronaldo Strips Down for Vogue Cover
"I resent the force-fed aspect of soccer. The same people trying to push soccer on Americans are the ones demanding that we love HBO's 'Girls,' light-rail, Beyonce and Hillary Clinton," Coulter argued, taking shots at an array of liberal targets. "The number of New York Times articles claiming soccer is 'catching on' is exceeded only by the ones pretending women's basketball is fascinating."
As TheWrap previously reported, World Cup soccer is catching fire, though perhaps not within the demographics she targets. In the USA's match last week against Portugal, 18.9 million viewers turned into EPSN, but the event wasn't exactly a hit in Middle America.
Is it because soccer is generally regarded as an international sport and there is a relative lack of diversity in the "red states" as compared to the larger markets on the coast?
See video: Will Ferrell Joins the US World Cup Team, Threatens to Bite Everyone
Whatever the reason, we imagine Coulter is pleased. "Any growing interest in soccer can only be a sign of the nation's moral decay," she asserted.
"If more 'Americans' are watching soccer today, it's only because of the demographic switch effected by Teddy Kennedy's 1965 immigration law. I promise you: No American whose great-grandfather was born here is watching soccer."


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Posted June 29, 2013
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Shalom and welcome!
I invite you to explore the website and learn about Israel, the Embassy and the special relations between our peoples.
H.E. Yossef Levy
Israeli Ambassador underscored that he strongly believes in the economic cooperation between the two friendly countries
The letter of condolences points out that the news of the attack in which four people were killed was received with deep concern, as well as the condemnation of this terrorist act.
Embassy of the state of Israel condemns with disgust the barbaric and anti-Semitic attack carried out by two Palestinian murderers against innocent prayers in Jerusalem synagogue
Young woman and IDF soldier killed in separate stabbing attacks.
PM Netanyahu: "The terrorism against us knows no borders. The terrorists and those who incite to it want to get rid of us wherever we are."
The Palestinians have carried out three terrorist attacks in Jerusalem in less than two weeks and instigated numerous riots on the Temple Mount. Incitement and the glorification of terrorists have played an important role in triggering the violence.
Monday - Friday
10:00 - 13:00


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Jasco's GE-branded Z-Wave Deluxe Hand-Held Remote has been named a 2007 Innovations Honoree in the Integrated Home Systems category for the 2007 CES Innovations Design and Engineering Awards.
Using Z-Wave technology, the RF wireless language created by Zensys, the remote wirelessly controls lighting and appliances. It offers features like separate node, group and scene functions, timed dim rate adjustments, and timer with calendar operations.
Just outfit an electrical outlet or lighting switch with a Z-Wave node, which wirelessly speaks to the remote with just a few button presses.
The remote is part of Jasco's new line of Z-Wave-enabled products, ranging from lamp and appliance nodes to built-in dimmer switches. The line will be available to retailers beginning March 2007.
Follow Electronic House on Facebook and Twitter.
Check out our recommendations for the season's best new TVs for home theater, living room or anywhere.
Home automation system helps wounded war veteran live more comfortably.
Check out our recommendations for the season's best new TVs for home theater, living room or anywhere.


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Prescott - Cannon
For more information please visit
Prescott Jazz Society
The Prescott Jazz Society was incorporated in 1994 as a non-profit membership organization. The Society was developed as the professional entertainment component to the edu-tainment program of the Cannon Academy of Performing Art which was founded in 1993.
Join Us! Sunday, December 14, 2014
ANNUAL Holiday Season Christmas Dinner Show & Birthday Party/Dance at the Hassayampa Inn, Prescott, AZ.
Christmas Dinner Menu
Your choice of Entrees: Pasta Primavera, Top Sirloin or Gilled Salmon served with salad, seasonal vegetables warm rolls and butter - plus Chef's Choice Holiday Desert.
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Live Las Vegas Show featuring the CUNNINHAM DUO - followed by a Birthday Party Dance w/MILT CANNON and the Reformed CANNONFIRE Blues Band


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Home COMMUNITY CHURCH HIGHLIGHTS: Second Sunday after Pentecost observed
CHURCH HIGHLIGHTS: Second Sunday after Pentecost observed
Second Sunday after Pentecost observed
St. Peter's Episcopal Church will observe the second Sunday after Pentecost with Holy Eucharist at 9 a.m. The Rev. Kathryn Macek will preside and preach. Morning prayer is offered at 8:30 a.m. Tuesdays and Thursdays in the chapel.
A midweek Eucharist is offered at 12:15 p.m. Wednesdays, also in the chapel.
Journey continues through Matthew
COVE — The Cove United Methodist Church will continue its journey through Matthew Sunday. Matthew 1:18-25 will be the scripture reference as the church focuses on the birth of Jesus and sees how the prophecy from Isaiah came to pass with Mary. The message title is "The Birth of Jesus the
The service will start at 9 a.m., with a coffee fellowship afterward.
'Praying Through the Troubles' is message
This second Sunday after Pentecost, Pastor Don Dunn's message will be "Praying Through the Troubles" at First Christian Church (Disciples of Christ), 901 Penn Ave. Scriptures will be from Psalm 86:1-10, 16-17 and Romans 6:1-11 at this 10 a.m. service.
Pastor give sermon advancing kingdom
COVE — Grace Community Lutheran Church will worship at 10 a.m. Sunday. Pastor Carl Seelhoff's sermon title is "Advancing the Kingdom" taken from Matthew 10.
Bible studies for all ages start at 9 a.m., with the adult class starting a series from Ephesians. Fellowship follows the service. All activities are held at the Cove Seventh-day Adventist Church.
Relationship with God is Sunday focus
Pastor Sue Peeples on the second Sunday of Pentecost continues her series on a personal relationship with God. The service starts at 11 a.m. at the United Methodist Church of Union. The message topic is "Live To God." Fellowship and refreshments follow.
A special "Pet Blessing" service will begin at 11 a.m. June 29, led by Pastor Mike Lamb on the church lawn. The greater community is welcome to bring their animals and join the church for the service.
The church plays host to Fresh Food Alliance from 12:30 p.m. to 1 p.m. Monday.
Senior lunch is served at noon Tuesday, followed at 2 p.m. with Emotions Anonymous, a 12-step program for anyone desiring to explore emotional reactions to various situations. For more information, call Mary at 541-805-4826.
Wednesday prayer meeting is from 5 p.m. to 6 p.m. People with a prayer request should contact a church member or call 541-562-5848.
Southside Kids hosts free event Saturday
Southside Kids is hosting its first free #Fun4Families event, "Letterboxing," at 1 p.m. Saturday, at Southside of Heaven, 211 Fir St. Letterboxing involves finding hidden boxes, collecting stamp impressions and learning about places or things represented in the stamps. Those attending will create some stamps and log books and give families clues to some local sites to start their adventures. Kids and Teens must be accompanied by an adult. For more information, call Stacy at 541-805-9068.
Reconciliation is sermon focus
Reconciliation is one of the greatest words because of the experience it brings, says Pastor Michael Armayor of the Seventh-day Adventist Church.
How can we experience this reconciliation with God? Wha purpose does it offer for a more passionate life? This will be Armayor's focus at the 11 a.m. service Saturday at the La Grande Seventh-day Adventist church.
'Dead and Alive' is Sunday theme
ENTERPRISE — "Dead and Alive" is the celebration at Enterprise Community Congregational Church Sunday. Bible study starts at 9:30 a.m. and worship at 11 a.m.
Hymn sing salutes contributions
The second Sunday after Pentecost will be celebrated during the 9:30 a.m. worship service at the First Presbyterian Church. The contributions of Issac Watts to hymnody will be commemorated by a hymn sing interspersed by Psalms and scripture. Fellowship will follow the service.
A study of a Bible Miniseries begins from 4 p.m. to 6 p.m. Sunday at the home of Bruce and Terrie Andrews.
'Sins and Forgiveness' is sermon topic
ELGIN — The sermon Sunday at the Elgin United Methodist Church is titled "Sins and Forgiveness" by Pastor Gerald Hopkins. The service begins at 11 a.m. at the church, located at Seventh and Birch streets. Coffee and conversation will follow the service.
'Let the Word of Christ Dwell in You'
Doug Edmonds' lesson Sunday at the Church of Christ will be "Let the Word of Christ Dwell in You" coming from the passage Colossians 3:12-25.
Communion is taken every Sunday. Sunday morning classes are from 9:30 a.m. to 10:15 a.m., and worship service follows at 10:30 a.m. A children's church takes place during the sermon for the little ones.
Wednesday small groups are at 7 p.m. at various home locations.


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text: Chances are you will be packing your child's lunch sometime this week. With the average cost of a school lunch at $2.50 a day, WINK shows you how to make a healthy lunch for only around $1. Showing us how is Chon Tomlin from Save -A-Lot, and road scholars Abby Tinberg and Bob Ringer, who are helping to get word out about healthy choices.


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Internal Medicine, Kaiser South Bay Medical Center
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Dr. Samir M. Patel has been practicing medicine for 9 years. Dr. Patel graduated from the Mayo Medical School in 2005. He practices medicine in Harbor City, CA and specializes in Internal Medicine. Dr. Patel is affiliated with Kaiser Permanente Medical Center.
Gender: Male
Years in Practice: 9 Years
Languages Spoken: English
Medical School: Mayo Medical School
Graduation Date: 2005
Hospital Affiliations: Kaiser Permanente Medical Center
Specialties: Internal Medicine


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Wednesday, 26. November 2014
:: Home > General News > Anger over faulty ticket machines in Vienna
05. 10. 11. - 15:00
05. 10. 11. - 15:00
Public transport users in Vienna are infuriated as several ticket machines have failed to accept their bank cards.
Using bank cards to pay for tickets is currently impossible at an undisclosed number of machines at stations across the city, public transport agency Wiener Linien confirmed yesterday (Tues). The company explained that the error had to do with a recent update of the ticket machine's features. Bank cards should be an option to pay for various kinds of tickets at the affected machines in around two weeks, according to Wiener Linien. The enterprise appealed on clients to be prepared to pay with cash at all ticket machines these days.
The news came on the same day as speculations that the southern extension of the U1 and U2 underground lines were at risk. Daily papers claimed that Wiener Linien considered introducing new tram lines to Vienna's Favoritenn district instead of expanding the existing services in the coming years.
Vienna Greens Traffic Affair Councillor Maria Vassilakou refused to comment the speculations. She only pointed out that the possible extension of the U2 was a project of the next legislative period which will start in 2015 and end in 2020. Vassilakou became the city's first Green deputy mayor last year after the Social Democrats (SPÖ) had to seek a coalition partner due to their loss of a majority in seats in the city parliament.
Vienna's SPÖ branch – which is headed by Mayor Michael Häupl – and the city's Green Party presented ambitious plans to increase the shares of public transport and cycling in Vienna in the coming years. The coalition promised to invest more in trams, buses, U-Bahn trains and the federal capital's cycling network – despite the soaring debts of the city which Viennese SPÖ Financial Issues Councillor Renate Brauner tries to reduce.
Vienna's public transport network features around 4,300 stops. More than two million people use the city's trams, buses and underground trains each day. More and more newspapers claim to know that the annual pass will cost 365 Euros instead of 449 Euros from 2012.
Vassilakou and a team of SPÖ Vienna officials are currently debating whether Wiener Linien's ticket price system should be reformed. Especially the Viennese Greens have stressed they want to make more frequent usage of public transport more attractive and reward those who do so. At the same time, the price for a single ticket may increase. This kind of ticket costs 1.80 Euros. Passengers could be asked to cough up 2.20 Euros as of January 2012, according to reports.
Vassilakou's party promised to lower the price for single passes to one Euro ahead of the most recent city ballot which took place in October 2010. The left-wing faction also claimed the price for annual tickets would be reduced to 100 Euros if it joins the Viennese government for the first time in history.
Austrian Times
Write your comment to this article here
Glen Sweeney wrote on 06. 10. 2011 from Vienna about "Anger over faulty ticket ..."
They have another problem with their machines that is probably not widely known. Some weeks ago we purchased one way tickets to Marchegg from an OBB machine and at the same time we thought it would be a good idea to acquire return tickets. So, having pushed all the right buttons the machine issued us with tickets clearly marked Marchegg to Haufeldstrasse. But, when we tried to use the tickets we were informed that they were not valid and that you can't buy return tickets. But we had, so the first question is why do their machines issue tickets that are not valid and the second clearly is why on Earth don't they issue return tickets when it is safe to say that when most people travel somewhere they generally want to come back???
Brauner discloses austerity course details
» General News 2012-05-29
Viennese Social Democratic (SP�) Finance Councillor Renate Brauner has revealed how the city government plans to save one billion Euros within the next five years.
Ticket inspectors increasingly active
» General News 2012-04-24
Around 60,000 people were caught using Wiener Linien�s services without a ticket in the first three months of this year, according to company officials.
U-Bahn renovation replacement service details issued
» General News 2012-03-29
Wiener Linien has explained how it plans to compensate the partial shutdown of one of the city�s busiest underground lines.
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Glamour and glitz were out in force at the weekend as stars from Austria and further afield flocked over the red carpet into the Vienna City Hall for a night of awards, dance and partying!
Bonbon Ball crowns Miss Bonbon 2013!
» Panorama 2013-02-11
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The number of pilots and stewardesses leaving Austrian Airlines (AUA) because of the upcoming pay cuts is on the rise.
» Business 2012-05-29
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Coalition accelerates anti-corruption ambitions
» General News 2012-05-24
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How An Austrian Park Every Year Becomes A Lake
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Mad About Mammoths At Vienna Museum
A unique exhibition in the Austrian capital Vienna has proved a massive hit after bringing together for the first time some of the most famous frozen woolly mammoth remains.
Controversy Over Advert For Fucking Hell Beer
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Luigi Restaurant Cooks Up Delicious Delights For Winter Season
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Church Porn Star In Court
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Don't moan alone, the Ombudsman Investigates.
Why suffer in silence. Let off steam by letting our readers share your troubles. File your complaints about anything and everything here.
Our ombudsman David Rogers will try and help solve some of the problems from lazy civil servants through to incompetent companies – and at the very least the worst transgressors will end up in our weekly special report.


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By Don Jacobs Knoxville News Sentinel
CAMPBELL COUNTY, Tenn. — Before Elko was killed with a blast from a shotgun aimed by a Campbell County animal control officer, the Knoxville police dog had uncovered 125 pounds of pot, more than a thousand grams of cocaine and flushed out 21 suspected felons from attics, woods, sheds and drain pipes.
Full story:
Top drug-searching K-9 shot by animal control


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How to Make Friendship Bracelets: 12 Fun Friendship Bracelet Patterns!
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Easy Faux Chainmaille Bracelet
By: Jessah from The Beaded Passion
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Does making chainmail jewelry seem too difficult or intimidating? Then try your luck with this Easy Faux Chainmaille Bracelet. It looks like the real thing, but it is a simple twist on making chain bracelets. You won't believe it until you see it!
Project Type: Make a Project
Bead Type: Metal
Time to complete: In an evening
Bead Technique Used: Chainmail/Wirework
Bead Project Type: Bracelet
Difficulty Level: Easy
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A liquid transport system including a bag adapted to hold fluids, the bag being constructed of a flexible fabric. The bag has a top portion, a bottom portion and a sidewall portion forming an interior and exterior. The system includes a discharge port, a fill port and a series of injector ports on the bag providing fluid access to the interior of the bag from the exterior, where each of the ports are sealingly closable. The discharge port and the fill port are adapted to allow product to flow into and out of the bag, and the injector ports are adapted to accommodate an injector probe.
1. A method of mixing a flowable product within a transport container, wherein said transport container has an interior and a flexible bag positioned in said interior, said bag having a top portion, a bottom portion and a sidewall portion, and an interior, said flexible bag having a discharge port and at least one injection port and also having a vent port, each said ports being sealingly closable; said flowable product positioned in said interior of said bag, the method comprising of the steps of:
(a) providing a gas injection system, said gas injection system having an injection probe and coupling said gas injection system to said flexible bag by inserting said injection probe into the interior of said bag through one of said at least one injection port;
(b) flowing gas through said gas injection system and discharging said gas through said injector probe within said product;
(c) venting gas from said interior of said bag through said vent port;
(d) attaching a discharge line to said discharge port;
(e) discharging product through said discharge port after a suitable mixing period; and
(f) withdrawing said injection probe from said interior of said bag.
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10. A method of mixing a flowable product within a transport container, wherein said transport container has an interior and a flexible bag positioned in said interior, said bag having a top portion, a bottom portion and a sidewall portion and an interior, said flexible bag having a discharge port and at least one injection port, each of said ports being sealingly closable; said flowable product positioned in said interior of said bag, the method comprising of the steps of:
(a) providing a gas injection system said gas injection system having an injection probe and coupling said gas injection system to said flexible bag by inserting said injection probe into the interior of said bag through one of said at least one injection port;
(b) flowing gas through said gas injection system and discharging said gas within said product through said injector probe;
(c) attaching a discharge line to said discharge port
(d) discharging product through said discharge port after a suitable mixing period; and
(e) withdrawing said injection probe from said interior of said bag.
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19. A method of mixing a high solids content fluid product or high viscosity fluid product within a transport container, wherein said transport container has an interior and a flexible bag positioned in said interior, said bag having a top portion, a bottom portion and a sidewall portion defining a bag interior, said flexible bag having a discharge port and a plurality of injection ports, each injection port having an injector probe coupled to said injection port, each said port being sealingly closable; the method consisting of the steps of:
(a) providing a gas injection system and coupling said gas injection system to said injector ports;
(b) mixing said product for a period of time by flowing gas through said gas injection system and discharging said gas through said gas injection system within said product;
(c) venting excess gas from said interior of said bag;
(d) attaching a discharge line to said discharge port; and
(e) discharging product through said discharge port after a suitable mixing period.
This is a continuation application claiming the benefit of and priority to PCT/US2005/021567 filed on Jun. 17, 2005 and U.S. Provisional Patent Application Ser. No. 60/616,691 filed on Oct. 7, 2004 which is incorporated by reference herein in its entirety.
This invention relates to bulk fluid container bags, and methods to empty filled bulk fluid container bags.
Many fluids are transported in bulk containers, such as ISO tanks and shipping containers, railcar containers, 55 gallon drums and other bulk containers. Highly vicious fluids and fluids high in solids content present particular transportation problems, such as ease of discharge of a filled container.
Examples of high solids content fluids include pepper mash, fruit pulps, grape mash/musk, drilling muds, clay slurries, fish slurries, tomato products, inks, and paints. During transportation, a high solids content fluid can separate into a fluid portion and a solids portion. Upon arrival at the discharge location, the solids separation must be addressed. If the solids portion is dense, the solids will settle to the bottom of the container, requiring removal of the fluids from the top portion of the container and solids removal later. If the solids portion is light, the solids will float to the top and create a solids cap. While the liquid portion is easily discharged from the bottom of the container, the solids cap will remain and must be physically unloaded later. Unloading of the solids can be labor intensive, such as physically breaking up and shoveling the solids cap or solids bottom. To assist in unloading containers filled with high solids content, mechanical agitation has been utilized, such as by placing rotors, vanes or other types of mechanical agitators in the transport tank, or even rotating the entire container (see U.S. Pat. No. 3,132,846, incorporated herein by reference).
Air injection has also been a method of mixing (see U.S. Pat. No. 4,595,296 to Parks, incorporated herein by reference). In the Parks patent, a fluid filled tank has a gas injector (or injectors) fixed to the bottom of the tank connected to a distribution manifold within the tank. The injectors are attached to a source of suitable gas (air, nitrogen or other inert gas), and the gas pulsed into the injectors assist in fluidizing and homogenizing the liquid/solids stored in the tank. The gas injector generally includes a feed line and an accumulator plate positioned at the exit of the feed pipe to assist in shaping the released bubble shape.
Examples of highly vicious fluids include oils/lubricants, syrups, and resins. These types of fluids present discharge problems due to the inability of these fluids to easily flow, resulting in long discharge times. Discharge times can be decreased by heating the fluid, thereby lowering the viscosity and increasing the fluid flows. Generally, either the bottom of the container or the entire container will be heated. However, heat transport in a viscous fluid can be slow and inefficient, and hence, smaller containers, such as a 300 gallon container, are used to reduce the fluid volume to be heated. Even with these smaller containers, heat times and discharge times can still be excessive.
In certain circumstances, it is desirable to transport fluids in flexible bags in a fixed wall container. A disposable bag prevents damage/contamination to the transport container from the fluid and eliminates the need to clean the container after each use. For instance, transport bags are used to reduce the potential for tank contamination of the product when the transported fluid is food stuffs or food grade materials. In these instances, a transport bag can be constructed of food grade plastics and if needed, can be pre-sterilized prior to use. Additionally, transport bags can be used when transporting hazardous materials, thereby preventing contamination of the tank by the fluid. Bag transport of high solids fluids or vicious fluids, however, presents problems, as prior art mechanical agitation or air injection is generally not feasible due to the inability to position the agitation device into the interior of the bag.
A liquid transport system includes a bag adapted to hold fluids, the bag being constructed of a flexible fabric. The bag has a top portion, a bottom portion and a sidewall portion forming an interior and exterior. The system includes a discharge port, a fill port and a series of injector ports on the bag providing fluid access to the interior of the bag from the exterior, where each of the ports are sealingly closable. The discharge port and the fill port are adapted to allow product to flow into and out of the bag, and the injector ports are adapted to accommodate an injector probe. The system includes injector probes and an air injector controller to control the timing/sequence and duration of the injected sequence.
It is an object of the invention to provide a mixing system for transport containers that allows mixing internal to the container without a mechanical agitator.
It is an object of the system to provide a disposal bag for use in transport containers that provides a liner or bag and a means of mixing within the liner or bag.
It is an object of the invention to provide for transporting and discharging high solids content and high viscosity fluids.
It is an object of the system to provide a system for mixing with injected air within a mixing bag.
Shown in
Bag 1 has a top portion 2, a bottom portion 3, and side walls portion 4. In construction, bag 1 can be a cylinder shaped container manufactured from a blown plastic cylinder with the ends sealed. Alternatively, bag 1 can be manufactured from a single sheet that is rolled into an open cylinder with the seam sealed, and the cylinders ends subsequently closed and sealed, such as by heat welding, solvent welding, or other means known in the art. The bag 1 could also be constructed from multiple sheets welded into a rectangular shape or other shape, but such is not preferred as the additional welds or joints present additional potential leakage points.
Located on the top portion of bag 1 is at least one injection port 10. Injection port 10 is a location (port) on the top portion of the bag that can be opened after the bag has been filled and is adapted to sealingly accommodate an air or gas injection means (the injected gas can also vary depending on the application; inert gases, such as nitrogen, could be used when contact with oxygen could promote unwanted bacterial growth). A suitable injection port 10 includes an opening in the bag 11 sealed with a fitting 20. One type of an injection port 10 used is shown in
This injection port 10 is located at opening 11 in the bag 1. Positioned around the bag opening 11 is a seal member 12. As shown, seal member 12 is a 90 mil circular sheet of polyethylene heat welded to the bag material. Seal member 12 strengthens the area of the bag in surrounding the opening 11. If the bag is sufficiently tear resistant, the seal member 12 can be eliminated. Seal member 12 has an opening 13 which aligns with the bag opening 11. As shown in
One embodiment of the fitting 20 is two inter-mating parts; here a male and female threaded fitting with a passageway through the fittings, more fully described in U.S. Pat. No. 3,531,142 (incorporated herein by reference). As shown in
Other types of fitting connectors could be used in the injector port, such compression or quick connect fittings. Also, instead of a two piece fitting, the fitting could be a one piece closure, designed to mate with a structure molded onto the seal member 12 (such as an upstanding treaded cylinder molded onto the seal member 12). However, a two piece fitting 20 is preferred for disposable bags, as such a fitting 20 can be removed from the bag to be cleaned and re-used on another bag. With a two piece fitting, the fittings should be installed onto the bag material prior to closing the ends of the bag because the interior is not easily accessed after bag assembly.
The bag 1 can have a series of injection ports 10. Bag 1 also includes a sealable fill port 30, and can include a sealable vent port 35 and a sealable discharge port 40. The fill port 30 is generally positioned on the top portion of the bag 1, such as the center of the top portion, while the discharge port 40 is generally located on the sidewall near the bottom portion of the bag. The discharge port 40 and fill port 30 can be the same port, but this is not preferred when it is desired to re-circulate product prior to or during discharge of product from the bag, as later described. The fill port 30 and discharge port 40 are generally larger than the injection port 10 in order to accommodate product flows. For instance, for a bag designed for a 20 foot ISO container used to transport pepper mash product, a three inch diameter fill and discharge port have been used. If desired, the bag 1 could be equipped with several fill 30 or discharge ports 40. These ports can be constructed similarly to an injection port 10 or with other designs known in the art.
During filling, the fill port 30 is coupled to a product feed line, and product is pumped through the line and into the bag through the fill port 30. Once the bag 1 is suitably full, the product feed line is removed and the fill port 30 is sealingly closed. Feed lines and discharge lines can be attached to the appropriate port with clamps, quick connects, threaded fittings, or other connectors know in the art.
Discharge port 40 is a sealable port on the bag 1 that couples to a discharge line to allow product to be removed from the bag through the discharge port 40. The discharge port 40 may be attached to the discharge line through a valve body or a fitting incorporating a valve body 41, such as a gate valve, to allow controlled release of product. An appropriate valve can be built into the discharge port 40. Additionally, a �T� or �Y� type splitter fitting 43 may be coupled to the discharge port 40, as shown in
Positioned on the top of the bag 1 is a vent port 35 (an injection port 10 could be used as a vent port 35). Vent port 35 allows the user to bleed off unwanted gas pressure within the bag during filling, discharging or mixing. The vent port 35 may be constructed similarly to an injection port 10 or of other construction known in the art. Vent port 35 may be coupled to a pressure actuated device, such as a spring loaded check valve, to keep the air pressure within the bag 1 at or below a predetermined maximum value.
Injection ports 10 are adapted to accommodate an injector probe 50 at time of product discharge. Injector probes 50 are pipes, tubes or other air passageways with suitable fittings to sealingly couple to the injection port 10. Air injector probes 50 are inserted into the injection ports 10, and connected to a source of suitable gas for injection into the product, generally through an air injection line. The fully installed probe 50 will be almost as long as the bag is high, as the distal end of the probe 50 should be located near the floor of the bag (for pepper mash, 4-12 inched off the floor, with 6 inches being preferred).
Installation of a full length injection probe 50 in the closed environment of a transport container containing a filled product bag can be difficult, and hence, the injector probe 50 may be assembled in sections joined with suitable couplings 52, such as a threaded coupling. One embodiment of an injector probe 50 is shown in
An alternative design for the injector probe 50 is to build the probe into the injector port 10. For instance, a flexible tubing slightly longer than the bag height could be utilized as the injector probe. One end of the flexible tubing would be fixedly connected to the interior floor portion of the bag and the other end of the tube would be connected to a corresponding injection port 10, such as through an injector fitting 20. The flexible tubing may be opened at the bottom, or closed with an opening in the side of the tubing at a desired height above the bottom of the floor portion. In this fashion, the bag 1 could be shipped with injector probes 50 installed, and it is only necessary to connect an air line to the injection ports at the discharge site to initiate mixing.
The following operation will be described using a bag 1 having a single injection port, vent port, discharge port and fill port. For small bags, a single injection port may be suitable (for instance, a 300 gallon bag) but for larger bags, multiple injection ports are preferred. It is preferred that an injection port 10 be located near the discharge port 40.
The bag 1 is shipped empty to the fill location. The empty bag is collapsed, and is generally flat or may be folded to create a smaller footprint for shipping. At the fill location, the bag 1 is positioned within the transport container with all ports. The bag 1 is generally still in a collapsed state, but pick up loops may be attached to the exterior of the bag 1 to allow for attachment of the bag 1 onto the transport container. A fill line is attached to the fill port 30, and product then released or pumped through the fill line into the bag 1. The vent port 35 may need to be opened to allow venting of gases in the bag 1 while filling. Alternatively, prior to filling the bag 1 with product, the bag could be �inflated� by attaching a gas injector line to an injection port 10 and filling the bag with a suitable gas to ease the filling process. Once the bag is suitably full, filling stops, the fill line removed, and all ports sealed closed for transport. If the shipping container is a closed container where the top is not removable, it is preferred that either the bag height be less than that of the container height, or alternatively, that the filling stop before the bag is full. Space is required between the container top and bag top to allow an operator to climb into the transport container onto the top portion of the filled bag to access the ports on top of the bag, for instance, to remove and attach hoses, close ports, or other desired actions.
At the discharge facility, the container is opened and an operator climbs onto the bag 1 and opens the fitting 20 at the injection port 10 and inserts an injector probe 50. For a multi-piece injector probe (for instance a two section probe), the operator would insert the bottommost section into the injector probe 50, and the top section would then be threaded onto the bottom section, and the top section also inserted. The threaded coupling on the top section of the injector probe 50 is then treaded onto the fitting 20 at the injection port 10, sealing the probe 50 into the port opening. If the liquid phase of the product is in the top portion of the bag 1, it may be desired to inflate the bag prior to installation of the injector probes to avoid loss of fluid. This may be accomplished by attaching an air line (without a probe) to an injection port 20, injecting air and hence inflating any slack in the bag (keeping the vent port closed). If the solids have formed a cap on top of the liquids, the operator will have to force the probe 50 through the solids layer. To assist, the probe's distal end may be shaped to assist in piercing a solids cap.
Once the probe 50 is inserted, an air line or gas line 70 is attached to the injector probe 50. Each air line is connected to a valve, and the valves are connected to an air distribution manifold, and gas injection is begun. The values are operated by a controller 60 to control the cycling and duration of the air pulses to the injection ports 10. Suitable controllers are available from Pulsair Systems, Inc. in Bellevue Wash. To bleed off excess gas pressure, the vent port 30 is opened. While gas injection can be continuous, it has been found that pulsing gas into the system is generally more efficient. Further, while all injection ports/probes could be pulsed simultaneously (such as by having the air feeder lines tie into a common air distribution line) it is preferred to pulse each probe sequentially. For instance, a preferred pulsing pattern is to pulse from the back of the bag (furthest from the discharge port) to the front of the bag.
Gas is pulsed into the bag through the probe, and enters the product near the bottom of the bag. The rising air mixes the product and will break up the solids layer. After a suitable mixing period, a fairly homogeneous mixture is obtained, and the discharge port 40 can be opened, and product removed. Air injection may continue or cease during product discharge, dependent upon the product's characteristics. For instance, it may be advantageous to continue air injection for product which quickly separates, particularly injecting air near the discharge port 40 to avoid clogging of the discharge port.
Product fluids may also be re-circulated during mixing and/or discharging. Recirculation pumps product about the system to speed the mixing of the product to more rapidly achieve a fairly homogeneous product. Recirculation can be achieved by attaching a fluid recirculation line to a port on the bag. Generally, the recirculation line has one end attached to the discharge port 40, and the other end attached to a fill port 30 or an injector port 20 (henceforth referred to as a recirculation port). The recirculation line may be attached to the discharge port 40 by coupling to one end of a splitter fitting positioned on a discharge port 40. It is preferred that a gate valve or other valve is used to control flows through the two available paths in a splitter fitting. A pump then is actuated to draw product through recirculation system.
The bag 1 shown in
The controller 60 can be configured to accommodate a variety of pulse durations and cycle times. For instance, a Pulsair PLC controller system was used for air injection of pepper mash in a 20 foot ISO bag container configured similarly to that shown in
Injected air creates rising bubbles in the product, inducing a current in the fluid, thereby locally mixing the product. Each injector site will have a local area of influence that is the volume surrounding the injection site affected by the induced current, as depicted in
For mixing vicious fluids, current techniques include heating the product container. Air injection increases the speed of heat transport in the fluid, and hence, decreases the time to raise the temperature of the product to the desired temperature. In fact, if the injected air is heated prior to injection, the current method of directly heating the container can be eliminated.
The bag, injector probes, transport container and air injection system provide a fluid transport system capable of dealing with high solids or high viscosity fluids. Although the present invention has been described in terms of specific embodiments, it is anticipated that alterations and modifications thereof will no doubt become apparent to those skilled in the art which are intended to be included within the scope of the following claims.
Patent Citations
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Most notably I like Yeegos price quotes for an entire stay, not quotes based on the average nightly price like so many other hotel reservation websites do.
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push to 400 isoTaken by ditchbitch with a Lomography La Sardina - Möbius loaded with Agfa Agfacolor 200 film in Saint-Petersburg, Russian Federation. These tags describe this photo: россия, russia, спб, санкт-петербург, saint-petersburg, rayon, neighborhood, piskarevka, с-41, 35mm, 35мм, осень, autumn, 400, 200, lomography, sardina, la, ditchbitch, sashatanya, любовь, love, november, october, agfa, and push. Date: 2012-11. Time: Morning. This photo can also be found in the album осенью настроение всегда не очень / oct-nov 12 / la sardina.
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The Dakshina Kannada police have arrested seven persons for allegedly conspiring to eliminate two local businessmen.
Commissioner of Police Gopal B. Hosur told presspersons here on Tuesday that the police had recovered two cars, two motorcycles, two firearms and 29 bullets from the accused, in addition to Rs. 52,000 in cash.
Superintendent of Police A.S. Rao said that the police kept watch on a house in Bendorewell for three days based on information that associates of underworld don Ravi Poojary planned to eliminate a city-based businessman from whom they had sought to extort Rs. 5 crore. The gang-members were arrested when they arrived at the house on Monday.
The gang revealed that they had planned to eliminate one more businessmen in the city, he said.
Mr. Hosur said police would crack down on those helping underworld dons operating from abroad, particularly West Asia. He asked such youths to return to the mainstream or face police action. He warned private banks against hiring anti-social elements as "seizure agents", without checking their antecedents with the police. He said such banks would be served notices. One of the accused, Prashanth Shetty, who was facing a criminal charge, had been hired by three top banks in the city, he said.
He gave the names of the arrested as Prashanth Shetty (32) and Satish Shetty (36), both from Amblalpady in Udupi; Sudhir Pujary (22), Yatish Pujary (22), Praveen Carlo (29) and Amrut Karkera (24), all from Vamanjoor; and Suhail Ahmed (26) from Maripalla. He said Dinesh Amin, accused in another case and languishing in Mysore jail, too was involved. An employee of the jail, Mahadevaiah, who passed the information to Amin, had also been arrested.
He announced a cash award of Rs. 50,000 to the team of officers who foiled the conspiracy.
Keywords: Dakshina Kannada police, murder conspiracy


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