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Webinar: Los Cabos UnstoppableJoin us on 11/25 for the official destination update as the winter season approaches for Los Cabos.Register now
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Before Travel Weekly's Rebecca Tobin left for a weeklong cruise on the Crystal Serenity she downloaded the line's free "Storyteller" app. It enables users to customize iPhone photos with Instagram-style filters and frames and captions and share them via email or Facebook (either on personal pages or on Crystal's "Never Ending Journal" page), or as an actual postcard using a third-party program. Here she shares "photo dispatches" based on some of the photos she took and converted to Storyteller images. Previous dispatches: Arrival, Open Spaces and Water Pursuits.
I took this photo after the ship arrived in Venice and we were about to step into the ferry boat that would take us to Saint Mark's Square. I never get tired of taking these beneath-the-bow shots of ships. My other favorite view is to look up along the side of a ship when we're tendering up. I'm always impressed with the hardware, the precision of ship operation, the size and scope of the vessels.
The Serenity overnighted in Venice, which gave the passengers a little more time to explore this city in the evening, when it's a little less crowded. Venice is full of mysterious, quiet side streets and canals. But the foot traffic in its popular points, especially in the tiny streets between the square and the Rialto Bridge, can be maddening, even at night, so we were glad to have the extra time to take it all in. Sunset in Venice was full of magical moments. This photo was taken from the Rialto and shows the Grand Canal at a relatively peaceful interlude.
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Jaf Travel offers a seven-night trip to Guatemala visiting Guatemala City, Antigua, Chichicastenango, Lake Atitlan and Tikal.
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Flo Tours offers a 13-night trip spending four nights in Azerbaijan, five nights in Georgia and four nights in Armenia with departures in April and October.
With the "Paddington" movie set to debut Nov. 28 in the U.K. (Jan. 16 in the U.S.), the Draycott Hotel in London is offering a Paddington Bear Experience plan.
The Regent Porto Montenegro, located on the Bay of Kotor in Tivat, Montenegro, is celebrating its recent opening with an introductory rate on stays in specific room categories.
Il Salviatino, a restored villa hotel located about 15 minutes from downtown Florence, is offering a package focusing on Tuscan cuisine.
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StartUpHire is the place to find Director of Sales, Named / Strategic Account jobs. Review the list of Director of Sales, Named / Strategic Account career opportunities to the left. These Director of Sales, Named / Strategic Account jobs represent some of the most rewarding careers available.
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Director Strategic Accounts, East Region? Imperva, located in New York Imperva, the leader in Data Security, is looking to hire an experienced Director Strategic Accounts, East Region who has developed key relationships in Large Corporate Enterprise accounts and is looking to10/20/2014 New York, NY Save This Job
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Job ID 2014-2719 Job Location US-TX-Austin Category North American Sales Type Full-Time More information about this job: About Bazaarvoice: Bazaarvoice is based on a simple truth; when people talk to each other, people buy stuff they are happy about because they trust the10/22/2014 Austin, TX Save This Job
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subset: commoncrawl


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Weather conditions had improved in the area since Wednesday and rescue operations were likely to commence shortly.
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Mother Stages Daring Undercover Mission to Egypt to Rescue Daughter Abducted by Husband
Two years ago, Alex Abou-El-Ella's Egyptian-born husband Mustafa told her he was taking their baby daughter to visit friends. When he never came back to their home in England, Alex discovered that her husband had kidnapped their daughter and whisked her away on a flight to Egypt.
Now, the mom has reportedly gotten her daughter back after staging a daring rescue mission that involved flying secretly to Egypt, cloaking herself from head to toe in a traditional robe and veil, and grabbing her daughter when she was on a walk with an Egyptian relative.
Alex tells the British publication the Sunday People that she enlisted the help of author Donya Al-Nahi who has been described in the media as "Jane Bond" for her past rescue missions of children of British mothers abducted by their foreign-born fathers.
The two discovered the pre-school where Mona was enrolled and the apartment block where the now three-year-old was living.
Alex tells the Sunday People that she donned the conservative Muslim garb despite the extreme summer heat. She and her helper Al-Nahi hired a driver, arrived at the village Kafr el-Dawwar in the Nile Delta and staked out the apartment complex early one morning. Shortly before 9am, they saw Mona walking with a woman and another child.
"I got out of the car but I'm not used to wearing the long dresses so I kept pulling it up and walking funny," Alex said. "I was walking behind them, faster and faster, and saw Mona's hand a few meters away from me."
The 29-year-old mother explains that she struggled to avoid tripping on the long garb.
"I grabbed her, pulled her into my arms and the lady looked at my face – but all she could see were my eyes. She started screaming and fell over on the floor. She even left her son to one side and screamed," Alex recounts.
"I had Mona in my arms and ran to the car. But the door was locked. It's automatic so when the car stops it's locked and I couldn't open it. I was panicking but Donya managed to open it and pull Mona in. She then pulled me in but we couldn't close the door and I felt the woman breathing on my back. I just screamed, 'Drive,'" she added.
Mona called out for her "Mummy" but was referring to the other woman.
"I cried for days because the moment I took her I heard Mona scream out to the woman in Arabic, 'Mum, help me, Mum,'" Alex says. "I felt shocked and upset to hear those words coming out of her mouth about another woman. "But after half an hour she looked up at me and said, 'Are you my mum?'"
From there, they made the three-hour drive to Cairo International Airport, but the drama wasn't yet over.
Polish-born Alex was worried they would be barred from leaving by Egyptian immigration authorities. She came prepared with the Polish passport of her older child who has a different last name and then bribed an airport official to allow them to board a flight to London without going through the usual checks.
They arrived safely in London almost two weeks ago, and unlike the treatment she received, Alex has informed Mustafa that she now has their daughter.
The Sunday People reports that the couple met when the Egyptian immigrant was running a fast food stall in Slough. She told the paper that he "treated her like a princess."
They moved in together and in 2009 married at the local registry three months before their daughter was born.
Alex says she converted to Islam, but never practiced the religion.
Of the night Mustafa absconded with their child, Alex said she had not suspected anything was amiss.
She said, "The police said he went straight to the airport, bought a ticket and boarded the plane. Mona was named on his Egyptian passport but by law each individual has to have their own travel documents and hers were at home."
"I want to know how he managed to get through border control at Heathrow without proper ones," she says. "If a child buys cigarettes they ask for ID – but when a child is taken through border control they don't seem to care."
Alex explains that before devising the rescue plan, she had little hope of ever retrieving her daughter. British authorities had told her that they were powerless to get Mona back, while estranged husband Mustafa at times threatened her over the phone that he would never allow her to see Mona again.
Donya Al-Nahi reportedly did not take money for her services and was motivated only by the principle, saying "You only have one mother and no one has a right to take you away from your mum. But Alex was the real hero here. She took the girl."
In a 2003 profile of her, the New York Times wrote, "To her surprise, she discovered there was a demand for her services, in part because of the growing number of British women marrying men from Muslim countries, which, in a some cases, has led to irreparable culture clashes."
In April, TheBlaze reported on a similar rescue operation this time carried out by a Pennsylvania woman, Kalliope "Kalli" Atteya, who tracked down her son Niko after her ex-husband Mohammed wouldn't let him leave Egypt during a family visit.
This spring, like Alex, Atteya put on a burqa that revealed only her eyes and then grabbed Niko as he was getting off the Egyptian school bus.
(H/T: The Telegraph)
Read more stories from TheBlaze
U.S. Official: Al-Qaeda Planning Attack That's 'Going to Be Big,' 'Strategically Significant'
Source: Major Terror Plot Underway, Team to Carry It Out 'In Place'
Rookie Cop Fatally Shoots Gun-Wielding 14-Year-Old — Previously Charged with Attempted Murder — During Possible Gang Battle (UPDATE: Security Cam Video)
Liberal Radio Host: Conservative Policies Driving More Americans to Suicide
'There Is a Stench to This': Mo. Town Livid After Saudi National's First-Degree Murder Charge Dismissed
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B8TINGU has won 9,689 Achievements and 4 Challenges in 1231 games
Registered on 14 April 09 at 22:39
| Last site visit: Today at 14:41 |
Really good character design. Poor execution on the character. He is a grappler that needs to be at range..oh and he doesn't hit like a grappler should tough to use him
Congrats! You're just 5 days behind me ;)
what a boss!!!
Very nice :)
Congrats Manu :)
yay for me!
awesome Benigni
...there are
2 other comments
absolutely!!! :)
How do you like this game?
Interesting my TA app achievement won't unlock as I'm viewing this.
20 achievements out of 40 won | 23,300 tracked gamers have this game | Last played 24 Nov 14
| Given 4 stars by B8TINGU
9 achievements out of 20 won | 31,408 tracked gamers have this game | Last played 24 Nov 14
| Given 3 stars by B8TINGU
18 achievements out of 20 won | 1,508 tracked gamers have this game | Last played 23 Nov 14
| Given 3 stars by B8TINGU
I'm a casual achievement hunter.. looking for the elusive achievements.. I own all of my games. A great many of them I have not even started and TA won't recognize 0 point games, so please check my XBL profile as I always list any games with Multiplayer and I am always looking to boost any game on my profile (all we need is schedual) that I need the achievements in. I am also more than willing to help you out, even if I have the achievement you want, but I expect the favor returned. Please no friend request to my XBL profile as I have no room, add me here instead. Please no random game invites if you see me already in a MP game. You can message me with what you would like to work on or boost and I will get back to you. THANKS!
Copyright © 2014 TrueGaming Network Ltd, All Rights Reserved
Xbox, Xbox Live, and all other Xbox Live specific terms are registered trademarks of Microsoft Corp.
TrueAchievements is a proud member of the Xbox Community Developer Program
Concept, Design, Programming and Server Stuff by Rich Stone
aka TrueAchievement
Additional Design by Chris Greenhough
aka The Grey Man


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Lou Reed's Gear Up for Auction
By Jenn Pelly on June 17, 2014 at 3:22 p.m. EDT
The Facebook page for Lou Reed announced today that some of his music equipment is up for auction. The majority of Reed's gear will remain in the in-process Lou Reed Archive, some things will be sold to raise funds for the development of the archive itself. They'll be listed here on eBay over the coming weeks. The page has already listed three keyboards and some other gear.
Lou Reed Tribute Show to Feature Members of TV on the Radio, Light Asylum, Vaccines, More
By Carrie Battan on November 22, 2013 at 3:35 p.m. EST
Photo (c) Timothy Greenfield-Sanders
On November 24, New York's Bowery Electric will host a special show in tribute to the late Lou Reed, as Brooklyn Vegan reports. It's called "Last Great American Whale" and will include performances from TV on the Radio's Tunde Adebimpe and Kyp Malone, Shannon Funchess of Light Asylum, Ivan Julian of Richard Hell and the Voidoids, Lenny Kaye of Patti Smith Group, Kirin J. Callinan, Jeffrey Lewis, the Vaccines' Justin Hayward-Young, Kembra Pfahler of the Voluptuous Horror of Karen Black, Travis Johnson of Grooms, Drowners, and Shahzad Ismaily (who's worked with Reed, Laurie Anderson and Bonnie Prince Billy), and more.
Public Memorial for Lou Reed Announced
By Evan Minsker on November 12, 2013 at 8:30 p.m. EST
Photo (c) Timothy Greenfield-Sanders
The New York Times reports that there will be a public memorial for Lou Reed on Thursday at Lincoln Center in New York. It'll take place from 1-4 p.m. at the Paul Milstein Pool and Terrace. "No speeches. no live performances," reads his Facebook page. "Just Lou's voice, guitar music & songs - playing the recordings selected by his family and friends."
Lou Reed Recovering After Receiving Life-Saving Liver Transplant
By Evan Minsker on June 1, 2013 at 10:54 a.m. EDT
Billboard reports that Lou Reed is currently recovering after receiving a life-saving liver transplant. Reed's wife Laurie Anderson told The Times of London, "It's as serious as it gets. He was dying."
UPDATE: Lou Reed has delivered the following message via Facebook:
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Apr 20, 2012, 07.55 PMby Glenville Hughes
Thank you very much it is very cosy,but on the practical side the hood is a bit big but blow practicality i say i did it for the waaw factor. Glenville
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I'm from Malaysia. I love teen chat. This is a super cool website for teenagers! LOVE it!
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text:
Eye Health Center
Eye Fatigue
In this article
Eye fatigue or eye strain is a common and annoying condition. The symptoms include tired, itching, and burning eyes.
Eye fatigue is rarely a serious condition. Common sense precautions at home, work, and outdoors may help prevent or reduce eye fatigue.
Recommended Related to Eye Health
Understanding Astigmatism -- Diagnosis & Treatment
People usually complain of blurred vision, or children may not pass their vision exam at school before they're diagnosed with astigmatism. The doctor may use one or more of these four tests to diagnose astigmatism and measure its severity: Vision test. Using a standardized chart, patients read the letters they can see from 20 feet away. If your vision is 20/20, you can see at 20 feet what a normal eye can see from 20 feet. If your vision is 20/80, you can only see at 20 feet what a normal eye...
Read the Understanding Astigmatism -- Diagnosis & Treatment article > >
But sometimes eye fatigue is a sign of an underlying condition that may need medical treatment. If eye fatigue persists despite taking simple precautions, see your doctor. This is especially important if your eye fatigue is associated with headaches or with eye problems such as:
- Discomfort
- Double vision
- Significant change in vision
Causes of Eye Fatigue
Any activity that requires intense use of the eyes -- such as extended amounts of driving or reading -- can cause eye fatigue. These include extended periods of:
- Reading
- Writing
- Driving
Exposure to bright light or straining to see in dim light can also cause eye fatigue.
One of the most common causes of eye fatigue is staring for long periods at digital devices such as:
- Computer screens
- Smartphones
- Video games
This type of eye fatigue or eye strain is sometimes known as computer vision syndrome. It affects about 50%-90% of computer workers. Some estimates say computer-related eye symptoms may be responsible for up to 10 million primary care eye examinations each year.
The problem is expected to grow as more people use smartphones and other hand-held digital devices. Research shows that people hold digital devices closer to their eyes than they hold books and newspapers. That forces their eyes to work harder than usual as they strain to focus on tiny font sizes.
Digital devices may also be linked to eye fatigue because of a tendency to blink less often when staring at a computer screen. People usually blink about 18 times a minute. This naturally refreshes the eyes. But studies suggest that people only blink about half as often while using a computer or other digital device. This can result in dry, tired, itching, and burning eyes.
Symptoms of Eye Fatigue
Eye fatigue is associated with uncomfortable and annoying symptoms, such as:
- Sore or irritated eyes
- Difficulty focusing
- Dry or watery eyes
- Blurred or double vision
- Increased sensitivity to light
- Pain in the neck, shoulders, or back
These symptoms can decrease your productivity. They may be intensified by sleep deprivation. During sleep, the eyes are replenished with essential nutrients. Lack of sleep may result in persistent eye irritation.


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Working the night shift is no one's idea of fun, but it turns out that it might be really bad for your health, too. Women who work at night are at a much greater risk of developing breast cancer, according to a new study by Danish researchers in the journal Occupational and Environmental Medicine. The findings have raised new alarm bells about shift work, which the World Health Organization's International Agency for Research on Cancer has listed as a "probably carcinogenic" activity. Here, a guide to the latest findings:
What does the study say?
The study, based on a survey of women in the Danish military, found that women who worked at least three night shifts a week over six years were more than twice as likely to develop breast cancer as those that didn't. Furthermore, women on the night shift who considered themselves morning people (or "larks") were four times more likely to be diagnosed with breast cancer.
How is the night shift linked to cancer?
The study's authors hypothesize that the night shift disrupts the body's circadian rhythm, which affects levels of melatonin, a hormone that is believed to have healing, antioxidant properties. Melatonin levels normally increase during the darkness of night, but the artificial light of a night shift suppresses them.
What if women work fewer night shifts?
The risk of cancer subsides. Women who worked only one or two night shifts a week showed no increased risk of cancer. But environment isn't the only factor — the fact that larks are more vulnerable shows that those genetically disposed toward the morning undergo more debilitating disruptions when they work at night.
Have similar studies been conducted before?
Yes. Health organizations have recently cast a spotlight on health risks associated with disrupting circadian rhythms. In addition, scientists have studied the links between breast cancer and night shifts before, but they largely focused on nurses, whose increased incidences of breast cancer could be explained by greater exposure to radiation and other hospital-related treatments.
How authoritative is this study?
Third-party scientists say more work is needed to definitively establish a link between breast cancer and night shifts. While some say it's probable that a link exists, the study didn't weigh two of the biggest factors known to contribute to breast cancer: Diet and physical activity.
Sources: The Guardian, The Telegraph, TIME, UPI
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Updated: 02/08/2014 6:19 PM |
Created: 02/08/2014 5:20 PM
By: Erica Zucco, KOB Eyewitness News 4
An infant is fighting for her life after being physically and sexually abused by her mother's boyfriend, and police say the child had been referred to the Children Youth and Families Department by medical staff multiple times before the incident.
Police say doctors referred the four-month-old girl to CYFD three other times before this because of injuries she had. They say doctors also referred the mother's two year old daughter to CYFD at least once. Police say Friday night, the mother's boyfriend injured the infant to the point where she may not make it.
Police say 19-year-old Elijah Fernandez was likely on Spice when he abused the child.
"That baby, because of the trauma to her body was rushed to the hospital right away and a full investigation was launched," Officer Simon Drobik said. "I literally cannot explain to you what happened because it is so graphic you will not be able to air the charges."
Police responded to the child's apartment on Copper where she lives with her mother, grandmother and two year old sister around 11 Friday night. A criminal complaint says the baby's grandmother's boyfriend called them saying the baby was not breathing.
He later told them the baby had been in Fernandez's care while the mother was out doing laundry, and that Fernandez and the baby's mother often smoke spice.
When police got to the apartment, Fernandez told them the baby had fallen off the bed.
"We realized because of the trauma to the baby that that is not what had happened or transpired," Drobik said.
Police say Fernandez later admitted to slapping her because she was crying. A sexual assault nurse examiner evaluated the infant and found that more had happened.
Police interviewed everyone at the apartment. Officers say the mother could face charges.
Police say the two year old girl also living at the home was left in the care of the grandmother.
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Datchet Waters Sports Ltd, Horton
Datchet Waters Sports Ltd
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Cafe BrauerApril 24, 2012 No Comments
10/1/10 3:58:00 PM Lincoln Park Zoo Cafe Brauer Patio photography. © Todd Rosenberg Photography 2010Back
10/1/10 3:58:00 PM Lincoln Park Zoo Cafe Brauer Patio photography. © Todd Rosenberg Photography 2010Back
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Like pearls in a sea of obscurity, rare Mormon tabernacles dot the Western states desert as reminders of antiquated times of architectural mastery.
While about half of the 100-plus-year-old historic jewels have been razed or sold over the years, many have not only survived the century but are still functioning houses of worship.
The Granite Tabernacle is one of only 20 tabernacles that's made "The List."
Essentially an endangered species list kept by The Church of Jesus Christ of Latter-day Saints, it comprises only 58 of the church's most valuable historic buildings that are still being used for ecclesiastical purposes.
"Which means they have an additional level of protection and care that's exercised when work is done to them," said Scott Christensen, archivist for the Church History Department. "We're exceptionally careful not to remove important architectural, historical elements. Those are buildings the church probably will never sell or tear down."
Special church historical sites are included on another list.
Besides 20 tabernacles, 10 temples are on the ecclesiastical list, as well as 23 meetinghouses and five other kinds of buildings, like the Colonia Juarez Stake Academy, a private, church-owned high school in Chihuahua, Mexico.
The list sounds more elite when one considers the church operates 133 temples and builds roughly 450 meetinghouses each year.
In total, Latter-day Saints crafted about 74 tabernacles in the past 163 years. Saints started calling the large log meetinghouses in Council Bluffs, Iowa, in 1847, tabernacles. The last tabernacle was built in Ogden in the mid-1950s.
Between those time periods, but mostly in the 19th century, it was common for several congregations to join efforts under the direction of their stake leadership and construct meeting halls large enough for combined conferences.
Most were built with a unique style, design and budget. They were largely reflective of the fine craftsmanship of their makers, many of whom were trained in Europe and New England. And most of the beloved buildings mirrored their surrounding elements and material.
Saints from the Salt Lake City Stake in 1877 received permission to use discarded granite from the nearby temple to build their tabernacle on Temple Square. It's known today as the Assembly Hall.
Most tabernacles took from two to five years to complete. At least a couple, however, took about 16 years of off-and-on-again work.
Some tabernacles aren't technically tabernacles at all, Christensen said. "Some are pseudo-tabernacles, or ward tabernacles, because they were grand in size or design."
But Christensen said in order to qualify for tabernacle status, at least in Mormon context, it needs to have been built by a coalition of congregations, not just one ward or branch. The five "tabernacles" in question that were constructed by single units were built in Franklin, Idaho; Willard, Moroni, Cedar City and Randolph, all in Utah.
"But they called them tabernacles in the 19th century," Christensen said with a laugh. "So who are we to say they were wrong?"
During the 1930s and 1940s, heritage eventually gave way to practicality and the church found it could build larger, more practical buildings with advanced construction techniques in reinforced concrete, steel girders and glulam beams.
Ultimately, wide-roofed, short-walled, nondescript stake centers replaced the grand, high-walled tabernacle era.
The word "stake" is of ancient origin, but Latter-day Saints only started using the term "stake center" in the early 1960s after the massive Inter-stake Center was completed in Oakland, Calif., Christensen said.
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'Canes hire Nieuwendyk in scouting, advisory role
Sep 3, 2014, 11:51 AM EST
The Carolina Hurricanes added some experience to their front office group on Wednesday, hiring former Dallas GM Joe Nieuwendyk to serve as a professional scout and advisor.
"Joe brings a wealth of experience and knowledge to our organization," 'Canes GM Ron Francis said in a statement. "He will be based in Dallas, and will be a major asset to the Hurricanes in player evaluations."
Nieuwendyk, 47, was relieved of his duties in Dallas over 16 months ago and has been on the sidelines since, though not entirely out of the loop. Earlier this year, a report from Sportsnet claimed that Brian Burke, Calgary's newly-appointed director of hockey ops, was keen to bring Nieuwendyk aboard as Jay Feaster's replacement as GM.
In this new advisory role, Nieuwendyk will return to the type of position he held in both Toronto and Florida prior to landing the Stars gig.
- gbatap - Sep 4, 2014 at 12:57 AM
Was a crummy gm but had a good eye for talent. Did a great job starting the restocking of the franchises prospect cupboard.
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Police arrest 2 in Goldwater High School vandalism
Nov 5, 2014 • azcentral.comPhoenix police have arrested two former students in the vandalism of Barry Goldwater High School's football field last month. Richard Tafoya and Kody Sarkissian, both 18, allegedly drove a stolen Toyota Tundra across the school's football friend on Oct ... More
Goldwater: The man who ignited a revolution
Nov 17, 2014 • Washington TimesBarry Goldwater challenged conventional wisdom, asking: Why can't we have a voluntary option for our Social Security system, which is headed for bankruptcy? He declared that welfare ought to be "a private concern promoted by individuals and families, ... More
Goldwater at 50
Nov 19, 2014 • National Review Online (blog)While passing through Phoenix, Ariz., in June, One Flew Over the Cuckoo's Nest author Ken Kesey and his Merry Pranksters showed their support by spray-painting "A VOTE FOR BARRY IS A VOTE FOR FUN!" on one side of their hippie bus nicknamed ... More
Goldwater: Solar companies give APS some competition
Nov 6, 2014 • azcentral.comBarry Goldwater Jr. , Special to The Republic | azcentral.com 8:40 a.m. MST November 6, 2014. 0517111125kh sr- ... I don't recall Joe Galli, the former executive director of the North Scottsdale Chamber of Commerce, ever taking up the cause of ... More
Arizona airman dies in training accident in Nepal
Nov 6, 2014 • AZFamilySgt. Sean Barton, a 2003 graduate of Barry Goldwater High School, fell 20 feet off a metal structure and suffered a fatal head wound, according to his mother. ... Her son's body was flown to Phoenix on Thursday, in preparation for funeral services next ... More
Backers eye February dedication of Goldwater statue in Capitol
Oct 24, 2014 • Cronkite NewsPHOENIX – Members of Arizona's congressional delegation have asked House leaders to OK the installation of a Barry Goldwater statue in the Capitol's Statuary Hall by February, in time for Arizona Statehood Day. But local backers must first finish ... More
How not to squander Arizona's water legacy
Nov 8, 2014 • Arizona Republic... Udall, Bruce Babbitt and Barry Goldwater all understood the fundamental reality of life in the desert: Private citizens and organizations along with the state and federal government must work together to ensure reliable water supplies for the ... More
'Phantom of the Opera' phenom to perform at Barry Goldwater HS
Oct 27, 2014 • newszap.comPHOENIX -- Franc D'Ambrosio, known as the "Iron Man of the Mask" for his many appearances in the "Phantom of the Opera," will perform at 7 p.m. Sunday, Nov. 9, at the Barry Goldwater High School Auditorium, Phoenix. The concert is sponsored by the Arts ... More
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This work was performed at the College of Veterinary Medicine, Athens, GA.
Effects of Clopidogrel and Aspirin on Platelet Aggregation, Thromboxane Production, and Serotonin Secretion in Horses
Article first published online: 8 DEC 2010
DOI: 10.1111/j.1939-1676.2010.0647.x
Copyright © 2010 by the American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 25, Issue 1, pages 116–122, January/February 2011
Additional Information
How to Cite
Brainard, B.M., Epstein, K.L., LoBato, D., Kwon, S., Papich, M.G. and Moore, J.N. (2011), Effects of Clopidogrel and Aspirin on Platelet Aggregation, Thromboxane Production, and Serotonin Secretion in Horses. Journal of Veterinary Internal Medicine, 25: 116–122. doi: 10.1111/j.1939-1676.2010.0647.x
Publication History
- Issue published online: 11 JAN 2011
- Article first published online: 8 DEC 2010
- Submitted September 6, 2010; Revised October 5, 2010; Accepted October 13, 2010.
- Abstract
- Article
- References
- Cited By
- Antiplatelet agents;
- Laminitis;
- Thrombosis
Background: Critically ill horses are susceptible to thrombotic disease, which might be related to increased platelet reactivity and activation.
Objectives: To compare the effect of oral clopidogrel and aspirin (ASA) on equine platelet function.
Animals: Six healthy adult horses.
Methods: Horses received clopidogrel (2 mg/kg PO q24h) or ASA (5 mg/kg PO q24h) for 5 days in a prospective randomized cross-over design. Platelet aggregation responses to adenosine diphosphate (ADP) and collagen via optical aggregometry, and platelet secretion of serotonin (5HT) and production of thromboxane B2 (TXB2) by ELISA were evaluated. In horses receiving clopidogrel, high-performance liquid chromatography analysis for clopidogrel and its carboxylic-acid metabolite SR 26334 was performed.
Results: SR 26334 was identified in all clopidogrel-treated horses, although the parent compound was not detected. Clopidogrel resulted in decreases in ADP-induced platelet aggregation persisting for 120 hours after the final dose. ADP-induced platelet aggregation decreased from a baseline of 70.2 ± 14.7% to a minimum of 15.9 ± 7.7% 24 hours after the final dose (P < .001). Collagen-induced aggregation decreased from a baseline of 93 ± 9.5% to a minimum of 70.8 ± 16.9% 48 hours after the final dose (P < .001). ASA did not decrease platelet aggregation with either agonist. ASA decreased serum TXB2 from a baseline value of 1310 ± 1045 to 128 ± 64 pg/mL within 24 hours (P < .01).
Conclusions and Clinical Importance: Clopidogrel effectively decreases ADP-induced platelet aggregation in horses, and could have therapeutic applications for equine diseases associated with platelet activation.


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Experts expect changes in FL's 'post-caps world'
The Washington Examiner, May 29, 2014
Since the Florida Supreme Court struck down the $1 million cap on non-economic damages in medical malpractice wrongful death cases, lawyers and industry experts have questioned whether the decision will once again increase malpractice claims and insurance premiums, or even force doctors to leave Florida to practice in other states. In March, the court found in a 5-2 ruling that the 2003 law that imposed the cap violates the state constitution's equal protection clause. The court also disputed the existence of the medical malpractice insurance crisis that legislators cited when they supported the law.
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CLAP 3 - Pictograms
Put down your hog dog burrito, it time to learn the Chinese.4.58 / 5.00 4,830 Views
Hoenn Confirmed
Hoenn Intro Animated4.27 / 5.00 3,661 Views
Nites Episode 2
The second episode of Nites4.20 / 5.00 4,225 Views
In Soviet Russia...
Could have used more jokes. but the animation is... ok
Wow, did the government start distributing 10's?
It's one of those things that is just an interesting concept, however more could have been done with this there just weren't enough jokes.
Vedy Goot!
not bad. nice. short, but a little too short for me. anyway, who am I to judge, I don't even know flash.
I was plaaning un making more, but I went away for a week and the trial expired. That is shvy communism eis bettur, there is no stupid buying adobe.
it's alright
I guess it's decent for just starting out. it's definitly not top quality though. not that its expected to be. just work at it and youll get better.
You are to generous
No sorry
In soviet russia, yes sorry


text:
Population fluctuations of stoats, weasels and hedgehogs in recent years
Article first published online: 20 AUG 2009
DOI: 10.1111/j.1469-7998.1968.tb04368.x
Journal of Zoology
Volume 156, Issue 4, pages 513–517, December 1968
Additional Information
How to Cite
Jefferies, D. J. and Pendlebury, J. B. (1968), Population fluctuations of stoats, weasels and hedgehogs in recent years. Journal of Zoology, 156: 513–517. doi: 10.1111/j.1469-7998.1968.tb04368.x
Publication History
- Issue published online: 20 AUG 2009
- Article first published online: 20 AUG 2009
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A man that comes from a family of serial killers, becomes infatuated with a teenager, and insists on making her... : Erotica » Read
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Draft and Trade Talk Message Board
- Mike Mike Aug 28, 2014 4:59 PM Flag
Could also try to go WR/WR if Calvin is still there, but I wouldn't do it unless you're getting CJ + DT
- Mike Mike Aug 28, 2014 4:59 PM Flag
Based on that scoring system, this is a scenario where I'd consider grabbing an elite QB if one fell to me (I'd normally never do this). I'd want an elite RB but they'll likely be gone by then, so I think you'll end up with Brees + DThomas or something like that. Then go hard for an RB next round like Morris/Ball/Bell.
- Mike Mike Aug 28, 2014 4:51 PM Flag
Take one of the top 4 RBs. If you want a WR that bad, you'll have a shot at DT/Marshall/Dez next round.
- Reply to
trade offered: cutler and vincent for newton and cobbby Ace Aug 28, 2014 4:41 PMMike Mike Aug 28, 2014 4:51 PM Flag
Newton + Cobb
- Reply to
who to draftby Jduncan88 Aug 28, 2014 4:27 PMMike Mike Aug 28, 2014 4:50 PM Flag
Best player available, position doesn't matter at that point
- Reply to
Should I trade RG3 and Antonio Brown for Brady and Vincent Jackson?by Anas Aug 28, 2014 3:55 PMMike Mike Aug 28, 2014 4:15 PM Flag
I wouldn't
- Reply to
Keep which 2 for a keeper league??by AJ Aug 28, 2014 3:11 PMMike Mike Aug 28, 2014 4:14 PM Flag
Depends on the keeper costs but DT and Marshall
- Mike Mike Aug 28, 2014 3:31 PM Flag
Doubt there's ever a situation where you're using Bortles over any of those three unless they're hurt. And if Jamaal Charles gets hurt, Knile Davis is a usable RB.
- Mike Mike Aug 28, 2014 3:29 PM Flag
That'd be the only reason to keep them. Are there really no better QBs (at least starters) who are available? I'd rather just scoop someone of the wire if they get hurt than use a roster spot on Bortles.
- Mike Mike Aug 28, 2014 3:16 PM Flag
No. You'd never start him with those 3 way better QBs.
- Reply to
Travis Kelce or Tim Wright?by Trev Aug 28, 2014 1:32 PMMike Mike Aug 28, 2014 1:37 PM Flag
Neither if you can help it. Would probably take Wright for the upside, although he has a higher chance of returning 0 value.
- Mike Mike Aug 28, 2014 1:15 PM Flag
I'd take Maclin
- Reply to
just drafted..please offer any adviceby greek Aug 28, 2014 12:13 PMMike Mike Aug 28, 2014 1:14 PM Flag
Good team. I'd try to move Foster for a safer elite RB but overall can't complain if he's your RB2.
- Reply to
Trade Help???by Jackson Aug 28, 2014 12:21 PMMike Mike Aug 28, 2014 1:04 PM Flag
No, upgrade from Cutler to Ryan isn't worth the downgrade of Dez to Green.
- Reply to
WR Opinionsby David Vest Aug 28, 2014 1:00 PMMike Mike Aug 28, 2014 1:02 PM Flag
Still Hawkins, even in non-PPR. Keep an eye on Matthews, Latimer and Wheaton, but roster Hawkins.
- Reply to
Please Help Evaluate This Trade for meby Sheldon Aug 28, 2014 12:13 PMMike Mike Aug 28, 2014 1:00 PM Flag
You should get more for Rodgers. If you have both Rodgers and Manning, I'd assume you're pretty weak at RB and/or WR. Don't bother getting a QB back in return in the deal since you have Manning (assuming it's not a 2 QB league). You should be able to get a very good RB or WR for Rodgers.
- Reply to
Draft Grade Please. Honest Opinions are Appreciated. Thank you in advance.by Tam Aug 27, 2014 3:58 PMMike Mike Aug 27, 2014 4:36 PM Flag
I never mentioned Peyton.
Also, yes Peyton will score a ton of points, but so will most QBs with those settings. With QBs, you can't look at raw point totals (they'll always be highest), you have to compare them to other QBs. A rising tide raises all ships. The value differential of the best RBs compared to middling RBs is much greater than the best QBs compared to middling QBs.
- Reply to
Rate this Team 1-10 ??by Mike Aug 27, 2014 4:05 PMMike Mike Aug 27, 2014 4:07 PM Flag
7? Don't love your WRs
- Reply to
Draft Grade Please. Honest Opinions are Appreciated. Thank you in advance.by Tam Aug 27, 2014 3:58 PMMike Mike Aug 27, 2014 4:05 PM Flag
Highly doubt SEA risks Harvin returning kicks, but your point that WRs/RBs that have a chance at return touchdowns are more valuable in this league is sound
- Reply to
Cooks or Watkins-Dynasty Leagueby Brett B Aug 27, 2014 3:44 PMMike Mike Aug 27, 2014 3:54 PM Flag
Preseason means little to nothing
Expert Fantasy Advice
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INTERESTING: Manufacturers Join LABI In Supporting Guidry Over Hughes For Supreme Court Seat – Dead Pelican
It's all about the support of "ambulance chasers" for Hughes. Not too surprising.
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Basyx by HON Midback Mesh Chair with Arms
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Basyx by HON Midback Mesh Chair with Arms
Weights & Dimensions
Additional Weights & Dimensions
|Product Type: Executive & managerial chairs
|Base Finish: Black
|Base Material: Metal
|Exterior Seat Material: Fabric
|Upholstered: Yes
|Locking Adjustments: Yes
|Swivel: Yes
|Back Height: Mid-back
|Adjustable Height: Yes
|Tilt Control: Yes
|Waterfall Edge: Yes
|Lumbar Support: Yes
|Casters: Yes
|Armed: Yes
|Weight Capacity: 250 Pounds
|Commercial Use: Yes
|Country of Manufacture: China
|Assembly Required: Yes
|Product Warranty: 5 Year limited warranty
About the ManufacturerYour office. This is the place where you must look, feel, and be successful. You want choices that accommodate all your needs, now and in the future. Your furniture has to be easy to order and available when and where you need it. You expect high quality and long-term relationships. You expect this in your business. You should expect nothing less of your furniture. Basyx has the furniture for you.
Basyx by HON Midback Mesh Chair with Arms
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OUR SKU # BYX2614Midback Mesh Chair with Arms is also sometimes listed under the following manufacturer numbers: HVL571.VB10


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