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Alnylam CEO: Novartis' cuts to RNAi a 'miserable predictor' of success
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- Don Seiffert
- BioFlash Editor- Boston Business Journal
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A decision by drug giant Novartis to cut back on its research into a field of drugs known as RNA interference has been cited as spurring a selloff at Cambridge biotech Alnylam Pharmaceuticals. But Alnylam executives says the news doesn't really mean anything for their firm.
"I think it's probably fair to say that Big Pharma's decisions on technology is probably a miserable predictor of whether that technology will work," said CEO John Maraganore today, after the website FierceBiotech reported on Monday about Novartis' plans to cut 26 employees working on the RNAi program. The website on Monday said "the news ... represents another setback for Alnylam and the field."
But Maraganore said today that big pharmaceuticals companies have frequently cut back on areas of technology that later turned out to be successful, including recombinant DNA in the 1980s (which has been used in hemophilia treatments and hepatitis B vaccines) and monoclonal antibodies in the 1990s, which has been the basis for drugs for rheumatoid arthritis and blood cancers.
"So maybe it's a badge on honor to have this," Maraganore said.
He also said that Novartis's 26-employee program was "hardly robust," and that Novartis was probably opting to focus on the areas in which it's already been successful. Besides, Novartis's RNAi drugs were all in cancer, which have been difficult targets for the technology, which interferes with the creation of deficient or harmful proteins by mutated DNA. Alnylam, by contrast, has focused on RNAi drugs for rare diseases of the liver, where the technology has shown success, he said.
As of 1:30 p.m. today, Alnylam's stock was trading at $54.25, down just 4 percent since the markets opened on Monday. It's likely the stock's 40-percent decline since mid-February had more to do with a pullback in the wider biotech market than on doubts about Alnylam's technology, which continues to show promise in mid-stage trials in several rare diseases.
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HARRISBURG, Pa. (AP) — The two surviving children of sports great Jim Thorpe won a critical ruling Friday in federal court that could clear the way for his remains to be removed from a mausoleum in the Pennsylvania town that bears his name and reinterred on American Indian land in Oklahoma.
U.S. District Judge Richard Caputo ruled in favor of sons Bill and Richard Thorpe and against Jim Thorpe borough in northeastern Pennsylvania, saying the town itself amounts to a museum under the 1990 Native American Graves Protection and Repatriation Act.
The men's lawyer, Stephen R. Ward of Tulsa, Okla., said they will now pursue the legal process to have their father, who won the decathlon and pentathlon in the 1912 Olympics, returned to Sac and Fox land in central Oklahoma.
Messages seeking comment from lawyers for the borough, and top borough officials, were not immediately returned. They could appeal Caputo's decision.
Ward said the brothers were pleased with the decision.
"They and their brothers and other members of the family have wanted this and have worked for this for a long time," he said. "They well remember how the wishes of the Indian members of the family were not respected concerning their father's burial."
After Jim Thorpe died without a will in 1953 at age 64, third wife Patricia Thorpe made a deal with two merging towns in the Poconos, Mauch Chunk and East Mauch Chunk, to have the new town named for him. His remains have been kept for the past six decades in a borough-owned roadside memorial along the Lehigh River.
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Pet Sympathy Quotes
Anyone who has lost a dear pet, whether it's a dog, cat, bird, horse or fish I want to let you know that you have my deepest empathy. I know the sorrow and pain you are experiencing first hand. Losing our pet can be devastating and heartbreaking. Each person will handle this loss differently, which is why pet sympathy quotes was put together. It is here to help you express your feelings and cope with this tragic event. It is difficult to know what the proper etiquette is to do at this time. What do you do? What do you say to someone who has just lost his or her pet? How do you let them mourn?
Pet loss quotes and loss of pet quotes can be used along side pet sympathy quotes in a variety of manners. Some of the more creative uses have been with inscriptions for hand made personal gifts, memory books and sympathy cards. Writing of fond memories that you shared, a short personal note or a heartfelt message acknowledging the loss can go a long way. It can be daunting and difficult to write exactly what you are feeling in a card or memory book, but I have accumulated an extensive list of quotes, sayings and poems that will help with your sympathy message.
Our pets mean so much to us. I hope that these pet sympathy quotes help you and others know that you care for them and are thinking about them during these difficult sorrow filled times. Pet Sympathy Quotes are ideal for people who need to know that you are there for them and that you care.
Pet Sympathy Quotes
When I play with my cat, who knows whether she is not amusing herself with me more than I with her. —
Until one has loved an animal, a part of one's soul remains unawakened. —
What the heart has once owned and had, it shall never lose. —
The heart of grief, its most difficult challenge, is not "letting go" of those who have died but instead making the transition from loving in presence to loving in separation. —
The death of a pet can trigger a grief response that is as deeply felt as when a friend or family member dies. —
My grief lies all within, and these external manners of lament are merely shadows to the unseen grief that swells with silence in the tortured soul. —
All that is worth cherishing begins in the heart, not the head. —
Heartbreak is life educating us. —
Friendship doubles our joy and divides our grief. —
Many people have heard the remarkable example of devotion involving a Skye terrier dog who worked for a Scottish shepherd named Old Jock. In 1858, the day after Jock was buried (with almost nobody present to mourn him except his shaggy dog) in the churchyard at Greyfriars Abbey in Edinburgh, Bobby was found sleeping on his master's grave, where he continue to sleep every night for fourteen years. —
It's the things in common that make relationships enjoyable, but it's the little differences that make them interesting. —
Death is the passing of life. And life is the stringing together of so many little passing's. —
The pain passes, but the beauty remains. —
A true friend is the greatest of all blessings, and the one which we take the least thought to acquire. —
The reason a dog has so many friends is that he wags his tail instead of his tongue. — Unknown
All that is worth cherishing in this world begins in the heart not the head. —
I believe that imagination is stronger than knowledge, Myth is more potent than history, Dreams are more powerful than facts, Hope always triumphs over experience, Laughter is the cure for grief, Love is stronger than death. —
Dogs don't know about beginnings, and they don't speculate on matters that occurred before their time. Dogs also don't know — or at least don't accept — the concept of death. With no concept of beginnings or endings dogs probably don't know that for people having a dog as a life companion provides a streak of light between two eternities of darkness. —
The greatness of a nation and its moral progress can be judged by the way its animals are treated. —
The average dog is a nicer person than the average person. —
Hope is the thing with feathers — that perches in the soul — and sings the tune without words — and never stops, at all. —
Give sorrow words. The grief that does not speak whispers the o'er-fraught heart, and bids it break. —
To spare oneself from grief at all cost can be achieved only at the price of total detachment, which excludes the ability to experience happiness. —
Unlike some people who have experienced the loss of an animal, I did not believe, even for a moment, that I would never get another. I did know full well that there were just too many animals out there in need of homes for me to take what I have always regarded as the self-indulgent road of saying the heartbreak of the loss of an animal was too much ever to want to go through with it again.To me, such an admission brought up the far more powerful admission that all the wonderful times you had with your animal were not worth the unhappiness at the end. — Cleveland Armory
If you have a dog, you will most likely outlive it; to get a dog is to open yourself to profound joy and, prospectively, to equally profound sadness. —
Pet sympathy quotes.
I hope these have helped you. For additional quotes, please see…
Pet Loss Quotes Loss of Pet Quotes
One Response to "Pet Sympathy Quotes"
Thanks for the wonderful sayings…it helped me alot with the loss of my beautiful kitty..i miss him so much……


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Constitution: President Obama's nonrecess "recess appointments" can't be excused as over-the-top electioneering. This president has crossed over from socialistic extremism into lawlessness and, perhaps, impeachability.
The U.S. Constitution established a strong presidency — so strong that even one of the most esteemed founding fathers, Patrick Henry, worried it would be kinglike. But this week saw a president exceed even those broad constitutional powers because doing so fits his election-year narrative of a "do-nothing Congress" so well.
Now we have the makings of a banana republic, where the rule of clearly written constitutional law is compromised by a ruler's subjective whim.
The Constitution is crystal clear on the recess appointment authority of the president.
"The president shall have power," Article II, section 2 states, "to fill up all vacancies that may happen during the recess of the Senate, by granting commissions which shall expire at the end of their next session."
The Senate has not been in recess. And Congress' authority over when it is and isn't in recess is no small matter of parliamentary procedure. Rather, it is a power the Framers explicitly bestowed in Article I, Section 5:
"Neither House, during the session of Congress, shall, without the consent of the other, adjourn for more than three days."
Yet Obama on Wednesday, with no recess in effect and against the publicly stated position of his own Justice Department, made four "recess appointments."
Former Ohio attorney general Richard Cordray was named head of the Consumer Financial Protection Bureau — a new, intrusive federal agency established last year by the Dodd-Frank law — and three spots on the National Labor Relations Board were filled.
The GOP-majority House has been keeping Congress in session, using its lawful power to prevent Obama from steamrolling someone into the CFPB position outside the usual Senate confirmation process because, as House Speaker John Boehner explained Wednesday, "the agency it heads is bad for jobs and bad for the economy."
Some may say these are small-potato government jobs not worth a big confrontation. But if a president can trample the Constitution on these appointments, the door opens for similar abuses of power with Cabinet secretaries and judicial nominations.
As Boehner warned, "The precedent that would be set by this cavalier action would have a devastating effect on the checks and balances that are enshrined in our Constitution."
Senate Majority Leader Harry Reid, D-Nev., until recently agreed with the Obama and Clinton Justice Departments — and with just about every other legal expert, liberal, conservative and middle of the road — that presidents have to wait for Congress to be out of session three days before legally making a recess appointment.
Starting Over: A black woman who sold cake at flea markets to save enough money to open her own shop saw it vandalized and looted by those who claim white cops are the major problem facing black America.Natalie Dubose's Ferguson, Mo., business, Cakes & More, barely survived the arson, rioting ...
Media Bias: The lens through which the dominant media present events in Ferguson, Mo., projects a distorted, hall-of-mirrors image to the public. Report reality, not alternate reality filtered through ideology.NBC's idea of legal commentary Tuesday on the Michael Brown killing was to have Hollywood ...
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first problems with lagg, then problems with won games that was counted as lost cause time delay that was overpassed by the losing opponents.... now this!!!!!Before release a version or an update of a bad working version, it would be good if the programmers would be enough competent to prevent this problems to us players that just wanna have fun.Incompetent Programmers = bad working software = angry players (like me)Your answer dont helps me in any way to recuperate my lost points in cheated games or software problems. IT IS A SHAME!!!!
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The FOG Design+Art fair is pleased to announce a dynamic weekend lineup of lectures and interactive discussions with leaders in the design and art worlds. Benefiting the San Francisco Museum of Modern Art (SFMOMA), FOG Design+Art will be held from January 17 to January 19, 2014, at the Fort Mason Center Festival Pavilion with special preview events on January 15 and 16.
On behalf of Dwell and VividWorks, we are proud to announce the winners of the 2013 VividWorks Passport to Design Competition. We celebrate the first, second and third place winners, who out of hundreds of entries were judged by a panel of Dwell Editors, on their usage of products to create a complete, livable and furnished space.


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Photos of Kristen Stewart, Robert Pattinson and Taylor Lautner on Eclipse Set 2009-09-10 08:07:16
Photos of The Eclipse Cast on Set
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Photos of The Eclipse Cast on Set
Kristen Stewart
Robert Pattinson
Taylor Lautner
5 years
Robward looks good but I am having a problem with his sideburns. They were shorter in Twilight. In NM and now in Eclipse they are seemingly longer. It makes Edward look older because most 17 year old boys don't have such long sideburns.
Carolain-RD 5 years
team edward!
Carolain-RD 5 years
team edward!
inlove23 5 years
Hold on, did anyone just read that Kristin needs a stunt double for the motorcycle?
inlove23 5 years
Why can't I be Bella??? Sighh... two cute guys all to her in that movie!!
lalar97 5 years
lalar97 5 years
5 years
Robert & Kristen are FANTASTIC together. If they are together as a couple....GREAT for them. And everyone should leave them alone, so they can be happy!!!!
mickee 5 years
http ://www .youtube .com/watch?v= o2xa_JU995s GUYS NEW MOON TRAILER 3.... It's fucking awesome..please delete the spaces.
mickee 5 years
http ://www .youtube .com/watch?v= o2xa_JU995sGUYS NEW MOON TRAILER 3.... It's fucking awesome..please delete the spaces.
5 years
Girl next to Jacob is Bella's stunt double. Wig looks better as long as they keep the side part and flattened by hood, headband etc. Eclipse is happy times for Bella. A smile goes a long way on her!
Emii 5 years
Robert is beautyful
Emii 5 years
Robert is beautyful
zoet 5 years
Ahhh I love on set pictures :D
zoet 5 years
Ahhh I love on set pictures :D
vanzalicious 5 years
kristen's wig is better than the last photo..thank god! =]hey, does anybody know who is the girl with taylor in that pic??
vanzalicious 5 years
kristen's wig is better than the last photo..thank god! =] hey, does anybody know who is the girl with taylor in that pic??
mickee 5 years
I think She looks way better in new moon, But I still love Kristen. Weitz is better than Slade. And hey, I missed that eye to eye. aw!
maerob 5 years
they are both happy....aww i'm sooo excited....
Divinesally 5 years
I think she looks beautiful. they both look good and happy.
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More insurers will sell Obamacare plans on HealthCare.gov for 2015 enrollment than did this year, heartening advocates of the health-care reform law.
Bill Clinton predicts corporations will someday care less about maximizing profits and more about employees and society.
The U.S. formally joined ReCAAP, a Singapore-based, multinational organization battling piracy at sea.
It sure looks like Jeb Bush, a favorite of centrist Wall Street Republicans, will make a run for president in 2016, says Politico's Ben White.
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Obama emphasized that Americans were not acting alone but rather together with a coalition of Arab states and the support of more than 40 nations.
A record harvest will likely cause financial hardships on grain farmers due to a lack of rail service. Some point the finger at the oil industry for the problem.
The U.S. manufacturing sector expanded in September, while employment levels among goods producers rose to a two-and-a-half-year high.
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News Details
Red Bull rivalry overtakes Mercedes spat
For weeks the Formula One world has been riveted on a feud between championship contenders Nico Rosberg and Lewis Hamilton but after the Canadian Grand Prix on Sunday the Mercedes team mates have another rivalry to worry about. After a difficult start to the season, Red Bull returned to the top of the podium when Australian Daniel Ricciardo claimed his maiden F1 win, bringing Mercedes perfect start to the season to an end after six consecutive victories and five straight one-two finishes. While the buildup to the Canadian Grand Prix was dominated by talk of a spat between the Mercedes drivers, Red Bull team principal Christian Horner was warning that his team was not yet ready to throw in...
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Larry Schrader
Marketing Manager
3573 E 78th St
Cleveland, OH 44105
HQ Phone: 216-341-1832
Email format for @wirecloth.com
Direct Phone : 216-341-1832
20 - 49
Not Available
Materials/Manufacturing->Fabricated Products
SIC Code:
3496 - Miscellaneous Fabricated Wire Products
Their Marketing Manager is Larry Schrader. Their Lead411 profile is categorized under the Fabricated products industry. If you're checking for Cleveland Wire Cloth & Mfg email addresses, these are also available on Lead411 with the @wirecloth.com email addresses and possibly Larry Schrader's email. Cleveland Wire Cloth & Mfg is based in Cleveland, OH. You can also get Larry Schrader's linkedin info, twitter data, phone numbers, wiki and biography on their Lead411 profile. Their contact information is filed under the Fabricated products category. Some possible email formats for Larry Schrader are firstname.lastname@example.com, firstname.lastname@example.com, email@example.com, and email@example.com. If you sign up for our free trial you will see our email@example.com addresses.
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Larry Sloan - Executive
Located in Crocker, MO SLOAN CONCRETE CNSTR & EXCVTG has Larry Sloan serving as the organization's Owner. Need Larry Sloan's email, linkedin, phone numbers, facebook, wiki and biography? You can find essential contact information in SLOAN CONCRETE CNSTR & EXCVTG Lead411 profile, along with their SLOAN CONCRETE CNSTR & EXCVTG email addresses using the domain. Search for SLOAN CONCRETE CNSTR & EXCVTG on Lead411 under the Construction services industry.
Larry Stickney - Technology
Centralia Public Schools's Director of Technology is where Larry Stickney is employed. On the other hand, the organization's CEO is . They are based in Centralia, MO, and you can find their Lead411 profile filed under the Education/training industry. Larry Stickney's profile contains twitter, phone numbers, linkedin, wiki, and contact information, and you can also find other Centralia Public Schools email addresses on Lead411 with the @catnet.gen.mo.us domain. Some possible email formats for Larry Stickney are email@example.com, email@example.com, email@example.com, and firstname.lastname@example.com. If you sign up for our free trial you will see our email@example.com addresses.
Larry Stephan - Executive
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People Directory > Larry Schrader


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At the end of November, there's no such thing as leftovers at dinner. For 17 years, Basset Hound lovers from across the country have come to Charleston to attend the Carolina Basset Hound Rescue's Waddle Weekend. The finale of this weekend, packed full with yappy hours, raffles, dinners and pageants, takes place on King Street at Charleston's Christmas parade with over 100 decorated basset hounds, some of whom are still hoping for their Christmas miracles. All breeds are welcome, after all everyone needs am"basset"ors! Registration begins September 1. Special hotel rate for those who register before November 1.Tides Hotel, 1 Center St, Folly Beach. Friday, 6-8pm shag lessons; Saturday, 4-6pm "yappy hour" at the Tides, 6-10pm raffles; Sunday, 2pm Christmas Parade. (864)907-4735, www.cbhrwaddle.com.
Upcoming Events
Sunday, December 7, 2014 - 9:00pm
Saturday, December 13, 2014 - 9:45pm
Wednesday, December 31, 2014 - 9:45pm
Saturday, December 6, 2014 - 9:00pm
Thursday, December 11, 2014 - 8:30am
Saturday, December 13, 2014 - 9:00am
Friday, December 5, 2014 - 9:00am to Sunday, December 7, 2014 - 3:00pm
Monday, December 1, 2014 (All day) to Wednesday, December 31, 2014 (All day)
Saturday, December 6, 2014 - 9:00am
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UPDATE THIS! Please! I love this story and have read up to chapter 9 at other sites. ~NiRi
Author's Response: LOL! Thanks hon! I promise, more to come by this weekend! The plot bunnies are in full force! Hugs, Tari


text: 35 min wait told 20. Sat us right by the door hostess had door open most of the time. People standing up VERY close to table flipping their hair. My shrimp n scallops good, salad n bread good. My spouses lasagna all cheese very lil noodles kid meals ok. We ordered a specialty drink did not look or taste like... More


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The longer I live the more I see that things really are as silly as they seem.
Want to Present a Paper at ESC Boston 2015?
Max Maxfield 8 comments
I tell you, I need more hours in each day. If I was having any more fun, there would have to be two of me to handle it all. For example, I just heard that I'm going to be both a speaker ...
No 2014 Punkin Chunkin, What Will You Do?
Martin Rowe Post a comment
American Thanksgiving is next week, and while some people watch (American) football all day, the real competition on TV has become Punkin Chunkin. But there will be no Punkin Chunkin on TV ...
Making the Grade in Industrial Design
Rich Quinnell 12 comments
As every developer knows, there are the paper specifications for a product design, and then there are the real requirements. The paper specs are dry, bland, and rigidly numeric, making ...
Book Review: Controlling Radiated Emissions by Design
Martin Rowe 1 Comment
Controlling Radiated Emissions by Design, Third Edition, by Michel Mardiguian. Contributions by Donald L. Sweeney and Roger Swanberg. List price: $89.99 (e-book), $119 (hardcover).


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Wolcott has been promoted from digital media supervisor to VP interactive media director. In her new position, she will oversee all interactive media planning and buying and search engine marketing (SEM) services, and will be responsible for keeping MGH at the forefront of interactive media technologies.
Subscribe now to search our database of 6860 Baltimore Business Journal People on the Move submissions and download their contact information.


text: Day 4 of Toronto Fashion Week 10 frames from backstage and on the runway at Arthur Mendonca macleans.ca October 26, 2012 Twitter Facebook Google+ Share LinkedIn Reddit Email < > Photo of < of > Browse Arthur Mendoncafashion photography Advertisement About this author macleans.ca Macleans.ca administrator Other articlesWhy Obama's amnesty orders miss the markGood news, bad news + 31 more posts this week Maclean's Top Stories Is PKP the next Michael Ignatieff? 1 Comment Why Obama's amnesty orders miss the mark 2 Comments Jian Ghomeshi goes to court 3 Comments The truth about race and the police 4 Comments Black Friday is nigh: Hand over the #@$% T-shirt! 0 Comments Advertisement Post navigation Previous 'She will rise again,' says father of Malala Yousufzai Next Passports and fake marriages: Politics on TV, Oct. 26 edition


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Ferrari Pays Tribute to Schumacher; Manager to Make New Statements When There Are 'Significant' Updates
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By Rachelle Corpuz | May 12, 2014 1:03 PM EST
Ferrari has paid a tribute to retired German Racing Legend Michael Schumacher for his first Formula One (F1) victory at the Spanish Grand Prix. The racing star remains in a medically induced coma.
Fernando Alonso and Kimi Raikkonen were present in the big team photo with a motivational and inspiring message for Schumacher. "Remembering your first win with us #Forza Michael," the banner read.
Ferrari Formula One driver Michael Schumacher of Germany celebrates after taking the pole position at the end of the qualifying session for the Bahrain Formula One Grand Prix at the Sakhir racetrack in Manama in this March 11, 2006 file picture.
"Forza" is an Italian word used to cheer for someone. In Schumacher's case, "forza" is a way of telling the 45-year-old seven-time world champion to keep on fighting for his life. The tribute was made to commemorate Schumacher's first victory for Team Ferrari at the Spanish Grand Prix in 1996. Watch the highlights of the racing event here.
Schumacher was signed by Ferrari in 1996. Schumacher's performance at the 1996 Spanish Grand Prix was remarkable. In such awful wet conditions and after a bad start which made him fell back to the sixth position, Schumacher still managed to keep calm and maintain his composure, eventually winning the race in the end. The 1996 Spanish Grand Prix was held on June 2, 1996 at the Circuit de Catalunya.
The athelete won driver's titles with Team Ferrari for five consecutive years from 2000 to 2004.
Schumacher is still being treated at the Grenoble University Hospital after his skiing crash in December, according to German newspaper Bild as reported by HKcarworld.com.
"Bild's information is that Schumacher has not yet moved to a rehab clinic," wrote the German newspaper.
"Sabine Kehm only wants to make new statements when there are significant changes," Bild added.
It was in the middle of April when Kehm spoke about Schumacher's condition. She denied the reports claiming Schumacher has already woken up from coma. But she shared Schumacher had moments of consciousness and awakening.
Schumacher suffered brain trauma when he fell from 3,000 feet in a skiing accident in December. Schumacher was skiing with his son at a ski resort in the French Alps.
Hell Hath No Fury: Sterling's 'Mistress' V. Stiviano's Camp Responsible for Leaked Tape After Legal Wife Sued Her
WATCH Michael Schumacher's Practice Driving Session with 2015 C-Class Mercedes, Last Interview Before Skiing Accident; Fans' Tweets of Support Despite News Media's Absence
Hollywood Celebrities Mingle With Politicians and Journalists at White House Correspondents' Dinner
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text:
smudge potSyllabification: smudge pot
Definition of smudge pot in English:
nounNorth American
A container for a smudge (see smudge2).
Example sentences
- Although late cold snaps occur infrequently, growers in the North Coast are geared to mitigate the effects with smudge pots, overhead sprinklers, and wind machines, huge fans that keep cold air moving in the vineyards.
- Sometimes growers light smudge pots in hopes of blanketing the field with protective smoke and turn on giant fans in the field to keep the frost from settling on the vines.
- Starting from the East and holding the lit smudge pot, each person can bathe themselves in the smoke.
Definition of smudge pot in:
- British & World English dictionary
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Word of the day Sprachgefühl
Pronunciation: ˈSHpräkɡəˌf(y)o͞ol
intuitive understanding of a language's natural idiom…


text:
Has Hell frozen over?
Elan announced today that its N800 wireless touch controller is shipping—and it's early. This isn't a knock on Elan in particular, but we are so used to electronics manufacturers toying with our fragile emotions. It's nice to see someone giving back for a change.
This 4-inch handheld features a funky touchscreen with wireless web access, as well as control for Elan and compatible third-party control systems. It's also got a nifty graphical interface for real-time status and control of entertainment and other home systems.
"We are pleased to be able to get our eagerly awaited N800 controller into the hands of our Dealers earlier than scheduled," said Bob Farinelli, ELAN's president CTO. "With stellar color graphics displayed on a high-resolution widescreen display, this tiny handheld controller provides reliable wireless control of all your entertainment, theater, and whole-house systems, plus access to the Internet. The N800 suits every room in the house and is definitely not your father's clicker."
The N800 is available now for $1,200.Follow Electronic House on Facebook and Twitter.
The new smart home system allows you to monitor and control your yard's watering schedule.
Lutron lighting control and Crestron home automation bring light, entertainment and security to luxury home.
A look at the current and upcoming Blu-ray discs t that will support the new Dolby Atmos audio format.


text:
You can now filter search results with text. Example: "person: john" will search only person pages for "john".
"I'm Cupid, stupid, and I'm going to kill everyone Arrow doesn't like. That'll make him love me, right? RIGHT?!"
Spinning out of Spider-Verse, Jessica Drew is on a mission with some other Spider-Folk. Even if you've been reading the other Spider-Verse titles, there will be some confusion.
Tony Stark's been conspicuously MIA since the title jumped forward. Time to see what he's been up to!
Let's see if I can make a list of one hundred items
awesome list =D
Yay, One the wiki I created is on this list :P
Use your keyboard!
Log in to comment


text:
The First Word in Protective & Marine Coatings
A Product of Technology Publishing / PaintSquare
JPCL | PaintSquare News
| Durability + Design
| Paint BidTracker
Main News Page
Thursday, August 7, 2014
More items for
Surface Preparation
Jetstream of Houston LLP has launched a 40,000 psi air-powered waterblast control gun for surface cleaning and coating removal.
QuadraBlast offers simplified rigid lance construction and a light-weight control gun for easy operation, the company says.
Features include telescopic shoulder stock, spring-loaded trigger safety, and remote-style dump catridge.
Two Configurations
The QuadraBlast is available in single-trigger (weighing 13 pounds) or dual-trigger (weighing 16 pounds) configurations.
Jetstream's QuadraBlast is a 40,000 psi air-powered waterblast control gun.
The control gun has a 32-inch stainless steel lance barrel and a 1/4-inch nylon tubing air hose.
Anthony Washington, product manager, says the control gun "is designed to provide a high level of operator productivity and safety on the job, while also allowing multiple gun operations."
The gun uses a self-propelled rotating nozzle, eliminating the for an external air driver, according to Washington.
About the Company
Jetstream, a division of Federal Signal Corporation's Environmental Solutions Group, manufacturers industrial high-pressure waterblasting equipment, parts and accessories.
More information: www.waterblast.com.
Comment from Mike Tavary, (8/7/2014, 8:08 AM)
Has this been tested on removing 1/4" think elastomer linings, i.e. natural rubber used in acid tanks?
Join the Conversation:
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CS Unitec's hand-held scarifiers are an ideal alternative to small-area shot blasting for cleaning and preparing concrete & metal surfaces. firstname.lastname@example.com
The Technology Publishing Network
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Technology Publishing / PaintSquare, All rights reserved
2100 Wharton Street, Suite 310, Pittsburgh PA 15203-1951; Tel 1-412-431-8300; Fax 1-412-431-5428;
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The First Word in Protective & Marine Coatings
A Product of Technology Publishing / PaintSquare
JPCL | PaintSquare News
| Durability + Design
| Paint BidTracker
Four and a half years after it was proposed and one year after...read
| comment
One shipbuilder and one ship repair facility have each been hit...read
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In the Netherlands, thousands of stones topped with smart...read
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AkzoNobel's International brand has launched Enviroline 2405...read
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Temporary climate control equipment.
Dehumidifiers, Heaters, A/C, Power, More…
Toll Free: 866-379-2600
Job Site Pipe Blasting & Painting - Please click here to see the video.
The portable FasterBlaster by RBW is the most efficient way to blast clean pipe in house or on the job site. Find out more at www.rbwe.com.
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Recycling Machines, Dust Collectors,
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Schmidt Improves Portable Blasters
Schmidt's VBS System reduces blowdown intensity, prevents exhaust from damaging floor while using no screens or filters.
Reduces sound; Increasing safety. Call 1-800-231-2085
Blast with 92% less dust.
Graco EcoQuip Vapor Blast equipment performs as well as dry blasting, but reduces airborne dust up to 92%! Use less media, save money in material and cleanup. See our FREE shipping offer!
The Technology Publishing Network
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Have you ever seen someone hypnotized? Usually, it's absolutely hilarious. Normally quiet people running around thinking they're barn animals, saying things they would never say, doing things they'd never do. 412 more words
Married Alabama public school teacher committed sex acts on three different students.
Another public school teacher having sex with underage students. It's almost like we're getting one of these every week now.
68 more words
A married teacher has turned herself into authorities after she allegedly committed a sex act on a student, made out with another and sent explicit photos of herself to a third.
Adults Allegedly Shot Kids With BB Gun, Forced Sex Act on Toddler in Pennsylvania; 5 Charged (Warning: Disturbing Content)
Five adults in Pennsylvania were recently charged after allegedly forcing five young children to watch them have sex and shooting the kids with a BB gun, … 279 more words


text:
The Revolution will cost less than the Xbox 360. That's Satoru Iwata's latest droplet of Revolution-based information, and it'll no doubt help fuel rumours of low-priced launches, although some launch speculation can now be safely laid to rest.
It makes sense for the Revolution to come in at a lower price point than the
360, although we don't know how much the 360 will be selling for once the Revolution is launched--here's hoping the
games are cheaper, though.
[via Engadget]
Breaking News
Dying Light cancelled on Xbox 360, PS3
Featured Stories
Get a closer look at final retail Amiibos
Posted on Nov 22nd 2014 9:00AM
Barely Related: Star-Lord's dance-off, comet sounds
Posted on Nov 21st 2014 8:30PM
Games we love and hate
Posted on Nov 21st 2014 3:00PM


text:
Led Zeppelin Kennedy Center Honors Coverage
It's been a great year for Led Zeppelin fans, between the release of the Celebration Day concert album and DVD, a new book of Jimmy Page interviews and two new live Robert Plant releases. And this Sunday, Plant, Page and John Paul Jones will be among the honorees at the very prestigious Kennedy Center Honors ceremony in Washington, D.C. (also being feted at the event: blues legend Buddy Guy, David Letterman, Dustin Hoffman and ballerina Natalia Makarova).
Unlike the Rock And Roll Hall Of Fame, at the Kennedy Center event, the honorees don't perform: instead, they sit in the balcony with the President and First Lady and watch other artists pay tribute to them. The Kennedy Center generally keeps the list of performers under wraps until the event itself.
RELATED: 5 Reasons Dave Grohl Will Perform At The Kennedy Center In December
The show won't be broadcasted live: an edited version will air on CBS on December 26. But CBS Local will be there, live-tweeting the event from the Radio.com account. We'll also have a wrap-up after the show is over Sunday night.
– Brian Ives, CBS Local
More Led Zeppelin News On WCBSFM.com
Read More On WCBSFM.com:
- New Apps Let You Sing with John Lennon, Sit with Paul McCartney
- Beth Stern And The Story Behind Yoda The Miracle Cat
- Morrissey Storms Off Stage in Poland After Heckler Makes Him Feel 'Unsafe'
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- Watch The World's Tiniest Guard Dog Foil a Robbery


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How to Toilet Train Your Child [World Toilet Day]
Toilet training is a huge task in every parent's life. Many parents are unsure about when exactly to start potty training. Sometimes they usually start at a very young age and sometimes too late. Not all kids are comfortable using a toilet seat at a specific age, although most of the children show signs between 18 to 24 months.
Some children learn toilet etiquette in days, while some can even take months. Though it's a tasking job a parent shouldn't get frustrated. In fact the parent must keep his cool and support the child. Here are some suggestions from Dr. Keya Lahiri – Chief Pediatrician at Dr. D.Y. Patil Hospital that might help to make the training process simpler and faster.
Look out for signs instead of using age as an indicator
- When your child understands words about the toilet training process, that means he is ready.
- When your child controls the muscles responsible for elimination.
- When your child expresses a need to go verbally.
- When your child keeps a diaper dry for 2 hours or more.
- When your child pulls down diapers or underpants by himself.
- When your child shows an interest in using the potty or wearing underpants.
Basic steps for every parent
- Buy the right equipment
- Ditch the nappy
- Dress your child in clothes that are easy to take off.
- If your child doesn't co-operate or seem interested, just wait until he's willing to try again.
- Never make your child sit for more than five minutes.
- If your child misses the toilet, don't comment. Just clean it up without any frustration.
- Teach your child how to wash her hands after using the toilet.
- You'll need to wipe your child's bottom at first, until she learns how. Remember to wipe from the front to the back, particularly with little girls.
- Never force your child, let the potty act be done independently.
- Give your child positive praise for her efforts and lots of praise when she's successful.
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The Grain and Grain Processing Information Site
Tramco Inc., Wichita, Kansas, U.S., provides a complete line of chain conveyors, enclosed belt conveyors, elevators and ship unloaders. A unique combination of superior component selection, design engineering, years of experience across a wide variety of industries and customer-focused service have made Tramco the source of consulting and supply in bulk material handling systems.Since 1967, Tramco has produced innovative conveying equipment and has marketed its products internationally.More than 20,000 Tramco conveyors have been designed and put into service, with each developed and built for a particular application, in accordance to the customers' best interest. Tramco's engineering staff uses the most up-to-date technology to develop and produce manufacturing drawings. Customers may even receive their drawings via e-mail to assure the fastest review time possible.Automation is further extended through computerized fabrication layout, control punching and robotic cutting and welding. Tramco conveyors are further enhanced with a paint system consisting of a five-stage wash and dry process and interior and exterior paint application. The parts are painted and oven-baked prior to assembly. Spare parts are also manufactured on site, which permits timely response for critical spare parts orders. Tramco also provides conversion services to update a facility.
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Why this columnist will never be a theatre critic
Great acting is a wondrous thing, but it has a way of distracting you from the play you're watching.
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There are many reasons I would not make a good theatre critic. Having to write after 3 in the afternoon is one of them. Having to watch a new production of Oklahoma! is another. There's room in a lifetime for only so many musicals, and the last time I sat through "The Surrey With the Fringe on Top," I had the feeling I might be reaching my limit.
But by far my greatest flaw as a theatre critic would be my frequent inability to pay attention. That, I suspect, is a deal-breaker.
Critics are professionally required to pay attention. In an ideal world, to the play they're watching. There are important things — like direction, and costumes, and lighting, and sound — that the critic must think about. There are difficult parts, usually in Act 2, they can't daydream through. If a play is a new play, the critic needs to think mercilessly about the quality of the playwriting. And if it's not a new play, critics need to think wistfully about the better productions they've seen over the years. Of which, traditionally, there are many.
You have to be alert to be a theatre critic. There's a lot to keep track of. Which is my problem. I am far too easily distracted by the art of acting. If there's a good actor onstage, I often can't see past his or her performance. If there is anything more fascinating than watching someone completely and absolutely become someone else — Diego Matamoros as Roy Cohn in Soulpepper's production of Angels in America this summer would be a good example — I'm not sure what it is. It's magic, that's all. And that's all I can ever think to say about it, which is not a very helpful or instructive or informative position to take, critically speaking.
Oh, I know. The direction, and the costumes, and the lighting, and the sound — to say nothing of the script and the other performances — are far from incidental to a great performance. Actors as accomplished as Matamoros or, let's say, Fiona Reid — who is appearing in Soulpepper's production of Joe Orton's Entertaining Mr. Sloane this summer — do not work in a vacuum. But this doesn't mean I might not watch them in a vacuum. It's my downfall as a critic. Sometimes, I can't take my eyes off them.
Collaboration is in the DNA of an actor. The cast and company of a play is as intimate a collective as is possible without sex being involved. Which doesn't mean it isn't involved, from time to time. And if you think a one-hander actually is a one-hander, you haven't spent enough time talking to directors. The real excitement of theatre is the spark of people working with one another. But theatre's collectivity means that actors don't always get sufficient credit for being something as astonishing as an actor.
Really, how do they do it? They each have a body and a voice like everybody else, and yet somehow they convince us completely of a reality that we happen to know (or, we thought we knew when the house lights first went down) isn't real. With good actors this enchantment does not waver — not for a second, not even when they are upstage and all the action is down. Not when they are helping Madame Arcati on with her coat for the billionth time. And not when they are playing the first courtier or the messenger or the guard.
There's a magic in what good actors do that leaves me unemployable as a theatre critic. When a good actor is in front of me, criticism is always the last thing on my mind.
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first bout of diverticulosis. fever and abdominal pain with swelling.
Why my doctor prescribed 2 antibiotics: cipro and flaxyl to treat it? Isn one enought?
Added 4 Jan 2010:
I felt much better after second day, but I feel two antibiotics gave me nausea, lack of appetite, weak. Is this "normal".?
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Answers (1)
4 Jan 2010
Dear Hilda, Flagyl is also an anti protozonal treatment, not just an anti biotic. It is really strong and DO NOT DRINK alcohol on it or it will make you violently sick up. It treats amoebic dyssentery also. And certain other conditions. It is probably making you feel a little off, it can make you have a metallic taste and be pretty nauseous even without drinking, but, it is pretty effective as a medication. Watch out for yeast infections after this much anti biotic. Yes, you can use some of the monistat vaginal treatment during your course of antibiotics.
thank you so much! everythng makes sense now!!!
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Build-up to Budget 2014-15: New directions for industrial freight corridors?
Tue Jul 08 2014, 10:59 hrs
Budget FY15 is expected to give directions and sops for the countrys largest industrial-manufacturing project. The largest of these, the Delhi Mumbai Industrial Corridor, is planned over an area 20% more than the size of Japan till now the principal investor in the project. (Image source: Thinkstock)
Along with the eastern corridor, the cost of the two projects are now estimated at Rs 54,000 crore but fresh assessments including those on ancillaries show the cost could balloon up to Rs 80,000 crore by 2017-2018. The capital structure of DFCCIL will entail a debt equity ratio of 2:1. (Image source: Thinkstock)
The Budget has one scheme tailor-made for it the National Investment and Manufacturing Zones. But it will need to be supplemented with labour law relaxations and abrogation of the new Land Acquisition and Relief and Rehabilitation Act. (Image source: Thinkstock)
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|By Business Wire
Article Rating:
|February 24, 2014 11:00 PM EST
Toshiba Corporation (TOKYO:6502) today announced that it has developed the world's fastest device controller for embedded NAND flash memory modules compliant with the Universal Flash Storage (UFS) Ver.2.0 and UFS Unified Memory Extension (UME) Ver.1.0 standards defined by JEDEC Solid State Technology Association (JEDEC). An embedded NAND flash memory module integrating the controller achieves a random read performance about 10 times faster than modules compliant with the e•MMCTM [1] standard now widely used in low- to high-end mobile devices. The device controller secures a performance equivalent to that of Solid State Drives (SSDs) for personal computers in a package as small as a fingernail.
Toshiba presented the new device controller at the 2014 IEEE International Solid-State Circuits Conference (ISSCC) in San Francisco, California, on February 12.
Recent advances in CPU processing power and DRAM capacity in smartphones and tablet PCs allow users to enjoy more powerful applications, including high resolution video players and feature-rich games. Such devices also require embedded NAND flash memory modules as their main non-volatile storage. Going forward, the higher performance of embedded NAND Flash compliant with the UFS standard will secure its widespread use in high-end mobile devices.
Current embedded NAND flash memory modules are increasingly unable to store all the data required to execute commands received from the host in the on-chip RAM of their device controllers, largely because of its increasing size; the device controllers have to execute multiple reads of the command data from NAND flash memory, which slows command execution. The result is growing demand for improved random read performance and a better user experience. However, it is difficult to secure anything more than incremental improvement in random read performance, because it takes 10s of microseconds to read data from NAND flash memory.
Toshiba has developed a new device controller for embedded NAND flash memory module to overcome these issues.
The new device controller stores data for executing a command received from the host in the host-side DRAM, reducing the number of read operations from NAND flash memory. This halves the time required to process a read command. The procedure by which the device controller writes data to the host-side DRAM and reads data from host-side DRAM is compliant with the UFS UME Ver.1.0 standard, published at the same time as UFS Ver.2.0.
Toshiba has also developed a hardware engine that executes read commands received from the host in parallel and integrated it into the new device controller. It achieves more than two times higher random read performance compared with conventional technology.
These two new Toshiba technologies have realized embedded NAND flash memory modules with a device controller that attains over 60 kIOPS[2] in random read performance of 4 KB access[3]. This performance level is about 10 times higher than that of modules compliant with e•MMC Version 5.0.
The new device controller also integrates new, Toshiba-designed, analog circuit technology that enables UFS's ultra-high-speed serial communication at 5.8Gbps per lane, which avoids any increase in power consumption.
Mobile devices with an embedded NAND flash memory module that uses the new device controller will offer higher random read performances that will improve response time in user interactions and shorter application start-up times, enhancing the overall user experience.
Sample shipping of embedded NAND flash memory modules with the new device controller are scheduled to start in the first half of CY2014.
[1] e•MMCTM is a trademark and a product category for a class of embedded memory products built to the JEDEC e•MMCTM Standard specification.
[2] Input / Output Per Second, number of commands to complete in 1 second.
[3] Conditions are followings; number of NAND flash memory chips is 8, size of access region is 8 GB, and host latency is 1 microsecond.
About Toshiba
Toshiba is a world-leading diversified manufacturer, solutions provider and marketer of advanced electronic and electrical products and systems. Toshiba Group brings innovation and imagination to a wide range of businesses: digital products, including LCD TVs, notebook PCs, retail solutions and MFPs; electronic devices, including semiconductors, storage products and materials; industrial and social infrastructure systems, including power generation systems, smart community solutions, medical systems and escalators & elevators; and home appliances.
Toshiba was founded in 1875, and today operates a global network of more than 590 consolidated companies, with 206,000 employees worldwide and annual sales surpassing 5.8 trillion yen (US$61 billion). Visit Toshiba's web site at www.toshiba.co.jp/index.htm
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Nov. 22, 2014 05:45 PM EST Reads: 1,410
Cloud Expo 2014 TV commercials will feature @ThingsExpo, which was launched in June, 2014 at New York City's Javits Center as the largest 'Internet of Things' event in the world.
Nov. 22, 2014 05:30 PM EST Reads: 1,394
ARMONK, N.Y., Nov. 20, 2014 /PRNewswire/ -- IBM (NYSE: IBM) today announced that it is bringing a greater level of control, security and flexibility to cloud-based application development and delivery with a single-tenant version of Bluemix, IBM's
An entirely new security model is needed for the Internet of Things, or is it? Can we save some old and tested controls for this new and different environment? In his session at @ThingsExpo, New York's at the Javits Center, Davi Ottenheimer, EMC Senior Director of Trust, reviewed hands-on lessons with IoT devices and reveal a new risk balance you might not expect. Davi Ottenheimer, EMC Senior Director of Trust, has more than nineteen years' experience managing global security operations and asse...
Nov. 22, 2014 05:30 PM EST Reads: 1,232
Explosive growth in connected devices. Enormous amounts of data for collection and analysis. Critical use of data for split-second decision making and actionable information. All three are factors in making the Internet of Things a reality. Yet, any one factor would have an IT organization pondering its infrastructure strategy. How should your organization enhance its IT framework to enable an Internet of Things implementation? In his session at Internet of @ThingsExpo, James Kirkland, Chief Ar...
Nov. 21, 2014 09:15 PM EST Reads: 1,322