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Arizona Cardinals
Cardinals safety Tyrann Mathieu makes ESPN insider's all-rookie team
A torn ACL and LCL against the St. Louis Rams on Dec. 8. might have derailed the latter part of Tyrann Mathieu's first season in the NFL, but it didn't stop one prominent NFL analyst from selecting the Arizona Cardinals safety to his all-rookie team.
Friday, Mathieu, who had 68 total tackles, two interceptions, a sack and a forced fumble in 13 games, was named to ESPN insider Mel Kiper Jr.'s post-season squad of first-year players.
S Tyrann Mathieu, Arizona: He could also qualify at cornerback, or nickelback, but I put him here based on how the Cardinals used him. Great season, injury aside.
In addition to making Kiper's all-rookie team, Mathieu was named the No. 12 best rookie of 2013. But he wasn't the only Cardinal player to make the list.
Kiper also listed running back Andre Ellington as his No. 22 rookie. Ellington, a sixth-round pick out of Clemson, finished second on Arizona in rushing yards (652) and rushing touchdowns (3).
Most Popular
Cardinals Audio
- Steve Keim, Arizona Cardinals GM - Monday November 24Steve Keim discusses his disappointments from Sunday, most notably how the Cardinals did not match t
- Paulie Pigskin Report - Monday November 24It's the Paulie Pigskin Report with Paul Calvisi!
- Wolf's Bloody Knuckle Game Balls - Monday November 24There is only one Bloody Knuckle Game Ball recipient this week.
- Brock Huard, ESPN Seattle host - Friday November 21The Cardinals secondary will get physical with Seattle's wide receivers.
- Mark Schlereth- ESPN NFL analyst - Friday November 21ESPN NFL analyst Mark Schlereth breaks down the Cardinals' matchup with Seattle.


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Wipro shares gain on acquisition, order win report
MUMBAI (Reuters) - Wipro Ltd (WIPR.NS), India's No.3 software services provider, gained 1.8 percent in after the company in a statement on Sunday said it would acquire L.D. Waxson Group, a Singapore-based consumer goods company, in an all-cash deal worth about $144 million.
Dealers also attribute gains to reports in the Economic Times newspaper that Wipro has bagged a $200-million (10.9 billion rupees) technology service contract in Europe, citing a person with direct knowledge of the negotiations.
(Reporting by Abhishek Vishnoi and Manoj Dharra; Editing by Anupama Dwivedi)
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SAARC summit salvaged after handshake by leaders of India, Pakistan
A brief meeting between India's Prime Minister Narendra Modi and his Pakistani counterpart appears to have salvaged a summit of South Asian leaders, with all eight countries clinching a last-minute deal to create a regional electricity grid. Full Article
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WTO clinches first global trade deal in its history Full Article
Kashmir Attack
Ten dead in Kashmir's worst militant attack in more than a year Read
OPEC Meeting
Saudis block OPEC output cut, oil price sinks further. Full Article
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GDP growth set to weaken, business wants reforms more than rate cut Full Article | Related Story
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Twitter to start tracking users' mobile apps Full Article
Jaitley to Rajan
Jaitley likely to meet Rajan on Monday to urge rate cut Full Article
Banking Sector
India moves to allow more businesses to offer basic financial services. Full Article
Forever21 in India
Forever21 sets sights on Indian cities, but please hold the hot pants Full Article
Japan Economy
Japan inflation slows in October, output and spending show signs of recovery Full Article
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Get the latest news on the go. Visit Reuters India on your mobile device Full Coverage

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Dining out is a safer alternative to cooking at home, with patrons far less likely to cut themselves with sharp knives, suffer burns from scalding cookware, or slip on ill-placed banana peels. Dine safely with this Groupon.
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$12 for a breakfast meal for two (up to a $24.56 total value)
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Diners can enjoy such entrees as hand-dipped challah french toast, three eggs with grilled ham steak, and honey-smoked salmon along with their choice of beverage, from orange juice and chocolate milk to freshly ground coffee.
The crafty culinarians at Polonia, winner of a Silver Spoon Award for Best Ethnic Food from Orlando Home & Leisure, whip up an array of made-from-scratch Eastern European eats, including pierogi, kielbasa, and blintzes with traditional cooking methods. In addition to Polonia's selection of authentic Polish entrees, deemed "delightfully edible adventures" by the East Orlando Sun, the ethnic eatery tantalizes taste buds and slakes thirst with a scrumptious selection homemade desserts and a unique assortment of Polish beers and wines.
Prompt service, care with food prep, and delicious.Rich, Urbanspoon, 1/18/13
I always take my out of town guests here and never disappointed. The pierogis are awesome.patty731, TripAdvisor, 3/5/13
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Author Archives: Josh Whitener
Giving thanks with a grateful heart
As the days of November wane and people eagerly anticipate Christmas, a handful of churches are taking time to help members reflect on their blessings in the spirit of Thanksgiving…. Read more
Christmas lights show supports cancer research
INDIAN TRAIL – Pete Kimbell didn't intend for his Garden Oak Holiday Lights show to double as a fundraiser when it debuted in 2012; the show was simply meant to… Read more
Legal services project for veterans expands into Union County
INDIAN TRAIL – Veterans in Union County who are in need of legal aid now have a new place to turn for assistance. The Charlotte-based nonprofit Legal Services of Southern… Read more
Celebrating Thanksgiving through outreach
INDIAN TRAIL – Seven hundred local families in need could have the chance to celebrate Thanksgiving with a complete holiday meal, thanks to the efforts of local nonprofit Common Heart…. Read more
A fundraiser for felines
Community members, rescue activists and one south Charlotte business will band together this weekend to help unwanted, neglected and homeless cats. SOS Feline Rescue, a nonprofit partially based out of… Read more
Principal of the Year focuses on goal setting
MARSHVILLE – Dr. Kevin Plue didn't set out to become a school administrator. It was a desire to coach that first led Plue into education, but a growing desire to… Read more
A legend comes to life
INDIAN TRAIL – Two local kids had the chance to travel back in time to an era of hangings and witch burnings as they made their small-screen debut on the… Read more
Living her passion: Waxhaw 11-year-old to take the stage in Theatre Charlotte production
WAXHAW – Theater is more than a hobby for Ailey Finn – it's a way of life. The 11-year-old Waxhaw resident has been involved in stage acting since she was… Read more
Rea View Fall Festival returning this weekend
WAXHAW – Members of the Rea View Elementary School community will rally to support their school this weekend through the annual Rea View Fall Festival. The festival, which is open… Read more
Putting love into action
INDIAN TRAIL – It's been a big year for local nonprofit Common Heart. The organization expanded its food pantry, Common Cupboard, and nearly tripled the size of its thrift shop,… Read more


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DJ Mike Moody spins live at Diamond Pub in the Highlands. Special guest DJ John will be there as well. Diamonds is formerly Jillians at 630 Barret Ave. Never a cover charge and the place is amazing. 20,000 square feet of party space. 16 Diamond pool tables, almost 30 flat screens including 15 foot projection walls, ping pong, a beautiful covered deck and so much more. Join us for a great night. You will have a blast! 10pm til 3am! Don't forget "The Deck" happy hour 5pm til 8pm!
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MSU adds two fundraisers
by MBJ Staff
Published: December 5,2010
Tags: Mississippi State University, Perry King "P.K." Thomas IV, Wesley P. "Wes" Gordon
Wesley P. "Wes" Gordon and Perry King "P.K." Thomas IV recently began fundraising roles with Mississippi State University for the areas of student affairs and engineering, respectively. Gordon, a Columbus native, began his new duties as director of development for the Division of Students Affairs in mid-October. The division is a major university unit responsible for enrollment services, housing, financial aid, health services, student organizations, counseling, police, recreational sports and other student service functions.
A 2004 MSU physical education graduate, Gordon earned a master of science degree in sport administration from the university the following year. Most recently, Gordon was director of development for the University of West Alabama based in Livingston, Ala., where he oversaw the day-to-day operations of the institution's UWA Foundation.
Also joining Mississippi State as a fundraiser is Thomas, who serves as assistant director of development for the James Worth Bagley College of Engineering. He assists Bennett Evans, the college's development director, with fundraising activities. He began his official duties Oct. 15.
A Tupelo native, Thomas holds a 2003 communication degree from MSU and earned a master's in physical education and sport administration in 2008. For the past two years, he resided in Corinth and worked as a district executive for Yocona Area Council of Boy Scouts of America. Prior to that, he served for two years as an admissions counselor for Mississippi State.
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Cannes Style: Official Selections
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Yul Brynner, 1958
Here's a lesson in how to pull off a roomy, wide-shouldered silk suit. Step one: Gucci loafers. Step two: Be Yul Brynner.
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SiZe record label father releases album for hospital baby unit
Last updated at 11:52, Friday, 28 December 2012
A West Cumbrian record label boss will release a compilation album tomorrow to raise funds for the special care baby unit at the West Cumberland Hospital in Whitehaven.
Simon Mattinson, 36, of Whinlatter Gardens, Workington, runs SiZe Records UK and wanted to thank the unit for looking after his daughter Dee, who was born on December 29 last year.
Simon, who is married to Sarah, said: "Soon after she was born she was taken to the special care unit for a few days.
"Although she was only taken there as a precaution and was surrounded by babies much more in need of care than she was, she received treatment that was second to none.
"It was heartbreaking to see so many tiny poorly babies but equally amazing to see the way they were being looked after by the staff.
"Around spring I came up with the idea of raising some money for the unit to thank them for the way they looked after our little girl and also because it is no secret that the unit really needs charitable donations."
He said the most obvious way to raise the money was via his record label and in the autumn he began to ask bands to donate tracks.
Simon added: "Almost everyone I asked was keen to be involved and donate tracks to help the cause."
Musicians include local acts I Am Spartacus, With Lights Out, Glover, Colt 45 and Kontiki Suite as well as Demons of Ruby Mae and Paris band Big Money Makers. Former Shallow Call frontman Phil O'Driscoll's new project The Pen The Sword are also included on the album.
The album, called D, costs £5. It features 16 tracks and will be available from SiZeRecordsUK.bandcamp.com from tomorrow.
All proceeds will go to the special care baby unit.
First published at 11:51, Friday, 28 December 2012
Published by http://www.timesandstar.co.uk
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thank you for photo comment hun :D how ıs you ?? Jul 05
It's been like a year and for some odd reason, it occurred to me that I had a purevolume account. haha its been a longgggg time
Apr 28, 2010
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The Morning Mix
Feb 5, 2013, 8:00 AM EST
This is the week we put football in the rear-view mirror and focus exclusively on college hoops. Yeah I'm talking to you, Joe Casualfan. The Morning Mix is the place you need to go every morning for the latest news and notes from the CBB world.
Let's hit the links.
Tuesday's Top games:
7:00 p.m. – No. 2 Florida @ Arkansas
7:00 p.m. – Boston College @ No. 8 Miami
7:00 p.m. – Wake Forest @ North Carolina
7:00 p.m. – Villanova @ DePaul
8:00 p.m. – No. 13 Kansas State @ Texas Tech
8:00 p.m. – Wichita State @ Southern Illinois
8:05 p.m. – Illinois-Chicago @ Valparaiso
9:00 p.m. – No. 10 Ohio State @ No. 2 Michigan
9:00 p.m. – Florida State @ Georgia Tech
9:00 p.m. – South Carolina @ Kentucky
Read of the Day:
A powerful story from Alex Prewitt of the Washington post on Jamar Board, one of the most revered streetball players in the Washington metro-area. Known as "The Silent Assassin", who was cousins with former-Tennessee guard Bobby Maze and set a Goodman League single game record with a 75-point performance in a 2011 game. Board was found dead on December 29th with a gunshot wound to the head. It has yet to be determined if it was a murder or a suicide. Seriously, read this. (Washington Post)
This one is pretty cut-and-dry. Virginia lost to Georgia Tech this weekend. You rank the 'Hoos in the top-25, you get skewered in the Poll Attacks. Read It. (Eye on College Basketball)
Top Stories:
The top 10 dunks of the college basketball season: With the football season in the books, College Basketball Talk fills you in on what you've missed. Here are the ten best dunks of the college basketball season thus far.
Contenders and Pretenders: College Basketball Talk is helping you get situated now that the football season is over. Here is our list of National Championship contenders and pretenders.
Five sleepers and five upset specials to keep an eye on: College Basketball Talk briefly breaks down five teams that can make deep tournament runs and five teams that may bow out early.
UNLV forward Anthony Bennett leads CBT's Freshman of the Year rankings: Here's what you need to know about the top freshman in the country.
Michigan sophomore Trey Burke sits atop CBT's National Player of the Year rankings: Michigan guard Trey Burke leads our Player of the Year rankings through three months. Doug McDermott and Mason Plumlee aren't far behind.
Creighton/St. Mary's highlights 'BracketBusters' line-up: ESPN announced the pairings for the final installment of BracketBusters are Monday night. The marquee game features Creighton's Doug McDermott and Saint Mary's Matthew Dellavedova. In other action: Ohio @ Belmont, South Dakota State @ Murray State and Detroit @ Wichita State.
Shabazz Napier is UConn's closer: Despite not being able to play in any post-season games this season, the UConn Huskies continue to play hard, especially down the stretch. Shabazz Napier has been a big reason why, especially in overtime.
Wyoming's Luke Martinez has court date set for arraignment:
Hoops Housekeeping:
– We got horrible news out of Irvine, Calif., yesterday as it was reported that an assistant coach on the Cal State-Fullerton's women's team was murdered on Sunday night. (Orange County Register)
- The North Carolina Tar Heels are really banged up. Three key contributors are questionable for their game tonight against Wake Forest. (ESPN Tar Heel Blog)
- Michigan State guards Gary Harris and Travis Trice are questionable for participation in the Spartan's game on Wednesday against Minnesota. Harris is still battling back spasms and Trice is recovering from a concussion. (Detroit Free-Press)
- A Detroit-area businessman has pleaded guilty to conspiracy in a point-shaving investigation involving the University of Toledo basketball team from 2004-06. (Yahoo Sports)
- Former-Murray State guard Zay Jackson will 60 days in jail as part of the plea deal he reached stemming from his charges of wanton endangerment. (SB Nation)
- The court date for Wyoming guard Luke Martinez has been set. Martinez is facing a felony charge of aggravated assault and battery stemming from a Dec. 30 incident at a bar. (Casper Star-Tribune)
Observations & Insight:
– Why does everybody think college basketball sucks this season? (The Big Lead)
- The Towson Tigers got 20 points and 12 rebounds from Jerrelle Benimon en route to a 81-68 win over UNC-Wilmington on Autism Awareness Night. Jeff Goodman tells the story about how Towson head coach Pat Skerry coordinated this tremendous event. (Eye on College Basketball)
- Andy Katz got a bunch of good quotes from coaches regarding the BracketBuster pairings that were announced yesterday. (ESPN)
- In case you aren't too familiar with the slate of mid-major basketball, here are the rankings for the 13 televised BracketBuster games. (Big Apple Buckets)
- Ten things to know now that college basketball is suddenly relevant. (USA Today)
- Anybody else excited for the Trey Burke-Aaron Craft match-up tonight? Craft got the best of Burke in the first game. Could tonight be Burke's "Naismith Moment"? (UMHoop.com)
- Michigan will wear all-maize uniforms for the Ohio State game tonight. You might wanna put on sunglasses before you click the link. (The Dagger)
- It took Illinois just one month to plummet from the top-15 to the bubble. That's impressive. (The Dagger)
- Once a month Matt Norlander puts together a collage of the best college basketball photos. Here are January's best. (Eye on College Basketball)
- It looks like Jalen Rose had himself a good time in Bloomington for last weekend's edition of ESPN College GameDay. (Deadspin)
Do you like the new Morning Mix? Hate it? Have a suggestion or want something featured? Troy Machir will take all your praise, insults and inquiries via Twitter (@TroyMachir)
Wisconsin practices passing without a ball, results are disastrous (VIDEO)
Nov 27, 2014, 6:34 PM EST
This is hilarious.
Bronson Koenig, Duje Dukan step forward in No. 2 Wisconsin's win over Georgetown
Nov 27, 2014, 6:08 PM EST
Koenig and Dukan combined to score 18 points in the second half for the second-ranked Badgers.
Richmond loses reserve guard to left foot injury
Nov 27, 2014, 5:24 PM EST
Khwan Fore's averaging 7.5 minutes per game in two appearances this season.
Throwback Thursday: Gonzaga and Michigan State play best Maui Invitational game ever (VIDEO)
Nov 27, 2014, 3:54 PM EST
This might have been the best feast week game of all time.
Report: Gonzaga's Josh Perkins broke his jaw
Nov 27, 2014, 12:56 PM EST
Perkins was kicked in the face by a Georgia player.
Pregame Shootaround: Enjoy your Turkey Day!
Nov 27, 2014, 11:19 AM EST
It's not just football that's on today.
St. John's seniors say they 'grew up' against Minnesota, but have they?
Nov 27, 2014, 3:14 AM EST
A lot is riding on this season for St. John's. Can they consistently be the 'grown up' team they claimed to be on Wednesday night?
Late Night Snacks: Two ranked teams fall at the Battle 4 Atlantis
Nov 27, 2014, 3:07 AM EST
Two Big East teams made statements in the Bahamas, and No. 3 Arizona won the Maui Invitational.
The little things made a big difference in No. 3 Arizona's win over No. 15 San Diego State
Nov 27, 2014, 2:07 AM EST
Arizona scored 22 points off of 14 San Diego State turnovers, and that along with good foul shooting proved to be the difference.
D'Vauntes Smith-Rivera's shot propels Georgetown past No. 18 Florida
Nov 27, 2014, 12:56 AM EST
Georgetown committed 19 turnovers, but they shot 49 percent from the field and earned another quality win for the Big East.
Rick Pitino gets his 700th career victory, but his team remains cold from three
Nov 26, 2014, 10:22 PM EST
Through five games Louisville is shooting 24-for-105 from three. They'll need to shoot better than that when Ohio State visits next Tuesday.
#POSTERIZED: St. John's forward Sir'Dominic Pointer finishes with authority (VIDEO)
Nov 26, 2014, 9:11 PM EST
Sir'Dominic Pointer picked off Minnesota center Elliot Eliason's outlet pass and made the big man pay for his mistake.
Binghamton's leading returning scorer, rebounder takes indefinite leave of absence
Nov 26, 2014, 8:05 PM EST
Justin Reed was one of America East's best guards in each of his first two seasons, but that hasn't been the case in 2014-15.
Buddy Hield, improved shot selection the keys in Oklahoma's win over No. 22 UCLA
Nov 26, 2014, 6:42 PM EST
After launching 22 three-pointers in the first half, Oklahoma took a wiser approach to the offensive end of the floor as they outlasted No. 22 UCLA.
No. 5 North Carolina's loss highlights issues with their rebounding, toughness
Nov 26, 2014, 5:29 PM EST
It's hard to put too much stake in one loss, but there are a couple of things from this game that we need to keep an eye on.
Report: Iona reels in well-traveled transfer wing
Nov 26, 2014, 5:24 PM EST
Cameron Biedscheid averaged 6.2 points per game as a freshman at Notre Dame in 2012-13.
Ankle injury to sideline New Mexico's starting point guard three to five weeks
Nov 26, 2014, 4:37 PM EST
Joining Cullen Neal on the sideline is Arthur Edwards, who is expected to miss 4-6 weeks thanks to a dislocated finger.
Butler upsets No. 5 North Carolina in Battle 4 Atlantis opener
Nov 26, 2014, 3:51 PM EST
The importance of this win for Butler cannot be overstated.
If No. 12 Villanova doesn't have a star on their roster, no one told JayVaughn Pinkston
Nov 26, 2014, 3:19 PM EST
JayVaughn Pinkston is the leader and go-to guy for Villanova. And he is not their star because … why?
#POSTERIZED: Wofford's Justin Gordon dunks on defender (VIDEO)
Nov 26, 2014, 12:02 PM EST
Gordon is averaging 10.5 points this season.
Top Posts
- St. John's seniors say they 'grew up' against Minnesota, but have they? 1
- The little things made a big difference in No. 3 Arizona's win over No. 15 San Diego State 0
- Butler upsets No. 5 North Carolina in Battle 4 Atlantis opener 2
- If No. 12 Villanova doesn't have a star on their roster, no one told JayVaughn Pinkston 0
- JayVaughn Pinkston's block gives No. 12 Villanova a win over No. 19 Michigan (VIDEO) 2
- Maryland upsets No. 13 Iowa State as fearless freshmen mix with gritty veterans for balanced effort 3
- Rondae Hollis-Jefferson's selflessness during the Maui Invitational will help No. 3 Arizona in the long run 0
Most Commented
- Villanova's win is evidence of why VCU may have peaked as a basketball program (14)
- Rick Pitino on blow out win: 'We played four white guys and an Egyptian' (14)
- Michigan's John Beilein rips ESPN for late tip time during Tuesday's loss (13)
- College Basketball Talk's latest top 25: Kentucky reigns, but how far will Kansas, Florida slide? (5)
- Report: Gonzaga's Josh Perkins broke his jaw (4)


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Appeal denied, so Iverson must pay
WASHINGTON -- NBA star Allen Iverson must pay $260,000 for standing idly by and watching his bodyguard beat up another man in a 2005 bar fight, a federal appeals court ruled Tuesday.
The U.S. Court of Appeals for the District of Columbia Circuit rejected the Detroit Pistons guard's attempt to throw out the verdict decided by a jury in 2007.
Bar patron Marlin Godfrey accused Iverson's bodyguard, Jason Kane, of punching, kicking and hitting him with a bottle because he refused to vacate the VIP section at Washington club Eyebar to make way for the basketball star and his entourage. Godfrey suffered a concussion, a ruptured eardrum, a burst blood vessel in his eye, a torn rotator cuff, cuts and bruises, and emotional injuries.
A three-judge appeals court panel wrote that Iverson stayed out of the fray in the back corner of the VIP area, standing on a couch or bench and observing.
"The evidence in this case supported the jury's finding that Kane attacked Godfrey in a fight that lasted several minutes, and that Iverson stood and watched without attempting to do anything to stop the beating," the decision said.
Godfrey and another patron, David Anthony Kittrell, sued Iverson for $20 million, but the jury decided not to aware punitive damages and only compensate Godfrey $10,000 for his medical bills and $250,000 for pain and suffering. The jury did not find either of the men liable for assaulting Kittrell.
Copyright 2009 by The Associated Press
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Results 311 — 320
Office Assistant
Farmers Insurance — Burnsville, MN
we are currently interning and hiring people who have aspirations of being a insurance agent. You will be able to pick your own schedule and also there will be no salary cap. We prefer our agents to b…
Application Deadline: Available Year-round
Administrative Assistant
Lifting the Burden Errand & Concierge Service — Virtual
Assist with managing the day to day task of maintaining the office, sending email correspondence, scheduling client appointments, returning potential client calls and communicating with employees and …
Application Deadline: Available Year-round
Office Assistant for Marc Quadagno at Keller Williams NYC
Keller Williams NYC — New York, NY
Keller Williams is the largest real estate firm in the country and Marc Quadagno specializes in luxury lofts, townhouses and niche apartments in Manhattan. You will shadow and assist a Licensed Real E…
Application Deadline: Available Year-round
Office Assistant
All Around Aquatics — Brooklyn, NY
Looking to expand my business. The call volume and administrative duties have become to great for me to handle alone. I am in great need of an assistant/intern to help me take my business to the next …
Application Deadline: Available Year-round
Office Assistant
Evolutionary Enterprises — Philadelphia, PA
devising and maintaining office systems, including data management and filing; arranging travel, visas and accommodation and, occasionally, travelling with the manager to take notes or dictation at me…
Application Deadline: Available Year-round
Office Intern
Kid Orange Tech — Boca Raton, FL
Kid Orange Tech provides kid-friendly, 100% educational technology solutions to support classrooms and parents. As technology plays an increasing role in children's everyday lives, it is important to …
Application Deadline: Available Year-round
Apparel Design/Executive Assistant
Price Upon Request Inc — Virtual
Price Upon Request is an apparel design and manufacturing company in Los Angeles, CA. The company's head designer has over 2 decades experience in the styling, apparel and design business. In this pos…
Application Deadline: Available Year-round
Office Assistant
Houston West Chamber of Commerce — Houston, TX
The Houston West Chamber of Commerce is an organization dedicated to promoting business in the West Houston area. The position involves a lot of different activities on a day-to-day basis and is a gre…
Application Deadline: Available Year-round
Admin Assistant Intern
ExtraOrdinary Events — Emmaus, PA
ExtraOrdinary Events is a new company in the Lehigh Valley that will planning, organizing and assisting individuals, business organizations and governmental agencies with special events. We have 10 ye…
Application Deadline: Available Year-round
Administrative Intern
Armenian Relief Society Western USA iNC. — Glendale, CA
The Armenian Relief Society of Western USA, A 501 (c)(3) non-profit organization, is currently seeking a hard working and dedicated administrative intern at its headquarter on 517 W. Glenoaks Blvd. Gl…
Application Deadline: Available Year-round


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Home :: His & Hers Wedding Sets :: Three Piece Wedding Sets :: Three Piece
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I can't thank Joshua's enough for their extra effort to meet the deadline for our jewelry needs. We were "under the gun" to make our surprise...
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I was at first reluctant to order my best friends wedding ring here as this would be my first time purchase via this media as a resident of the Caribbean,...
Tri-color Braided Wedding Band
For sad reasons, I needed to replace my wedding band, which had been hand made 13 years ago. I searched for quite a while before I decided to order from...
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Microsoft keynote, it looks like a new phrase has been born -- "Pulling a Peter Moore."
According to folks at the Rock Band booth, people have been inadvertently pausing the game when they're trying to rock out, causing the music to come to an abrupt halt, and their friends and observers will shout out "Aw man, you just pulled a Peter Moore!"
Reminds us of Andy's "I Schruted it." line from The Office.
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Dying Light cancelled on Xbox 360, PS3
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Posted on Nov 20th 2014 2:00PM


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XM just finished up "IT" today, which was their Encycledia of Pop. They went through over 60 years worth of charted music in chronological order. It took well over a month and spanned all six of the decades stations. I know they've done it before, but this was the first time I listened as an XM subscriber. I only tuned in to the early stuff here and there, but I listened all through the 80's and 90's, which is the music I'm most interested in. It was an eye opening experience and a fun trip down memory lane; it brought about both smiles at the classics and a few groans at the duds.
Can't wait till they do it again- good stuff.
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Samsung is developing a Galaxy S4 with support for LTE-Advanced, which is able to reach nearly twice the speed of normal 4G. The phone may be sold in South Korea as early as this month, but given the lack of necessary infrastructure, it may never see release in America. Or anywhere else, for that matter. Nevertheless, Samsung's phone will still be the first LTE-advanced smartphone to ship anywhere in the world.
There's nothing like a fresh batch of source code to get you through another Monday morning. Samsung has just posted the kernel source for two of its newer S4 variants, the Galaxy S4 active (i9295), and the dual-SIM version of the Galaxy S4 Mini (i9192). Samsung has been on an open source run lately with the AT&T GS4 and Galaxy Tab 8.0 going up just last week.
If you're the developer type who really lives for this, grab the Jelly Bean code at Samsung's open source pages linked below.
Welcome to the latest entry in our Bonus Round series, wherein we tell you all about the new Android games of the day that we couldn't get to during our regular news rounds. Consider this a quick update for the dedicated gamers who can't wait for our bi-weekly roundups, and don't want to wade through a whole day's worth of news just to get their pixelated fix. Today we've got an interesting take on top-down strategy, a unique spin on zombies, and a word puzzler from an unexpected source.
Last week there was a bit of hubbub among the still-tiny population of Google Glass users, after Google sent out packages to the Explorer program. A few of them spotted UPS packages coming in through the My UPS service, and speculation ran wild. What could this 1-pound package be? A free Nexus 4? Keys to one of Google's self-driving cars? A golden ticket for admittance to the Google X Dream Factory?
The smartphone price wars are continuing after Amazon temporarily dropped the Sprint HTC One to $79.99 yesterday. Now Wirefly has taken the device down to only $49.99 with a new two-year contract.
Keep in mind this price is only available on new lines of service. That can mean a completely new account, or a new line on an existing account in this case. Upgrades on existing lines are $129.99. That's still a deal when you consider the $639.99 price tag on an unsubsidized Sprint HTC One.
"Many people don't realize … the majority of the world is not connected to the internet. How do we get cost-effective, inexpensive, and reliable connectivity to the remaining 5 or 6 billion people who don't have it?"
Chief Technical Architect Rich DeVaul poses this question in introducing the technology behind Project Loon – the newly (officially) announced project from Google X that aims to bring internet connectivity to "rural, remote, and underserviced areas," as well as those affected by natural disasters.
Imgur has become one of the standard Internet destinations for quick and dirty photo sharing, but its official Android app leaves a lot to be desired - though to be fair, it's still in beta. The latest update adds a much-needed Holo interface... sort of. The UI has definitely been improved over previous versions, and according to the changelog, it's Holo. While it's clear that the designers were trying for a more standardized app, the guidelines have been followed in some places and not others.
Google has updated the Play Support accepted payment methods page with a few new carrier billing options, including billing for subscribers of 3 in Hong Kong, Ireland, and Sweden. Wind Italy has apparently received carrier billing as an option, as well.
Oddly, Telenor of Sweden has been removed from the list as well, though we've not been able to confirm that the feature has actually been disabled. Depending on your provider, you may need to manually enable carrier billing as an option on your account page, as some 3 users are reporting.
CPU-Z has long been a popular tool on the desktop for identifying hardware components quickly and easily. Now that same power has come to Android with the first beta release of CPU-Z in the Play Store.
There aren't a lot of bells and whistles in CPU-Z, but it knows absolutely everything about your hardware. It'll ID your ARM chip down to the revision number, find software and kernel versions, track RAM and processor load, and list all of your internal sensors.


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Hot NewsRSS feed with Hot News
Latest news
Angelina Jolie Suffers From Complications After Her Breast Surgery!
Monday 2:26 PM, 04/11/2013
Angelina Jolie underwent surgery to remover her both breasts earlier this year. She got implants, but now she's suffering from complications...READ MORE ▶
Tags: Hot News
Latest news
Emile Hirsch Welcomes Baby Boy With Former Flame!
Monday 10:16 AM, 04/11/2013
28-year-old actor Emile Hirsch has welcomed his first child with an unnamed former flamed, E! News confirm. "The baby was born at a Florida ...READ MORE ▶
Tags: Hot News
Latest news
Niall Horan Fake Proposed To Katy Perry!
Monday 8:36 AM, 04/11/2013
Niall Horan, known from One Direction, has several times mentioned his crush on Katy Perry. This weekend he got extremely lucky, when he fin...READ MORE ▶
Tags: Hot News / One Direction
Latest news
Lea Michele Thanks Kate Hudson For What She Did After Cory Monteith's Death!
Monday 8:27 AM, 04/11/2013
Lea Michele has done her first open-hearted interview ever since the passing of her boyfriend and Glee co-star, Cory Monteith. The actress s...READ MORE ▶
Latest news
Portia De Rossi: "I Just Didn't Want To Be A Lesbian!"
Monday 1:02 AM, 04/11/2013
Portia De Rossi and her wife Ellen DeGeneres celebrated their fifth wedding anniversary in August this year, but Portia has now opened up a...READ MORE ▶
Tags: Ellen DeGeneres / Hot News
Latest news
Deets On Kristen Stewart And Robert Pattinson's Meet Up: "Very Platonic!"
Sunday 6:30 PM, 03/11/2013
Former Twilight sweethearts Kristen Stewart and Robert Pattinson were spotted together this week, five months after their split in May. Even...READ MORE ▶
Tags: Kristen Stewart / Hot News


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Jay-Z and Beyoncé's "Run" Movie Trailer Coming Never
For those of you awaiting the highly anticipated music video for Jay-Z and Beyoncé's "Part 2 (On the Run)", itttttt's here!!!!
Directed by Melina Matsoukas, the video is in a not so "cliché" movie trailer format as "RUN" presented by Roc Nation and Parkwood Entertainment and stars Sean Penn, Don Cheadle, Guillermo Díaz, Emmy Rossum, Jake Gyllenhaal, Blake Lively, Rashida Jones, Kidada Jones, and of course JAY Z and Beyoncé.
We gotta admit those JxB Carters sure have perfect damage control timing for sure.
Watch below:
Dope! You likey???? Hit the flip for more from the mini-flick…
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Pure Comedy: Funniest Reactions To Beyonce's Hilariously Wacky "7/11″ Video
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What's Wrong With Us? The Absolute Worst Songs We Know All The Words To
'How To Get Away With Scandal' Twitter Reacts To The 'Scandal' & 'How To Get Away With Murder' Winter Finales


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Sandwich Shop Restaurants
2789 Niagara St
Niagara Falls, NY 14303
(716) 205-8532
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Take Your Sandwich To The Next Level When Using Kraft Real Mayo!www.KraftRecipes.com/KraftMayo
Sandwich Shop Search Now! Over 60 Million Visitors.About.com/Sandwich Shop
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York's Social Sciences, Arts & Humanities rank in Canada's top fourYork University has ranked among the top four universities in Canada and in the top 100 universities in the world in the Social Sciences and Arts & Humanities categories in the 2014 Times Higher Education World University Rankings. "Our researchers are recognized as being among the top in the world. That expertise in research and scholarship fuels our teaching, with faculty bringing their innovative ideas directly into the classroom," says Dean Martin Singer. Full Story
Israel and Golda Koschitzky Centre for Jewish Studies celebrates 25 yearsThe Israel and Golda Koschitzky Centre for Jewish Studies will celebrate its 25th anniversary with a two-day international symposium delving into the state of Jewish studies. The State of Jewish Studies: Perspectives on Premodern Periods will take place on Sunday, Dec. 7, and Monday, Dec. 8. Everyone is welcome to attend. Full Story
Professor Emeritus Ian Greene launches new bookThe Charter of Canadian Rights and Freedoms: 30 Years of Decisions that Shape Canadian Life, written by Ian Greene, professor emeritus of public policy and law investigates how Canada's Charter of Rights and Freedoms has transformed Canadian life since it was adopted as part of the Canadian Constitution in 1982. Greene's book provides examples to describe the many significant ways the charter shapes Canadian life on a wide range of issues. Full Story
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Levittown, Puerto Rico
Del Valle Ave. 1829, 00950 Levittown, Puerto Rico – Show map
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64 verified reviews
We verify all reviews from guests who have stayed at Comfort Inn & Suites Levittown. Find out more.
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Comfort Inn & Suites Levittown's staff speaks: Spanish, English
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Comfort Inn & Suites Levittown
This San Juan hotel is in the center of Isla Verde nightlife and is just 80 ft from the beach. Many casinos and restaurants are within walking distance of the property.
Score from 116 reviews Good
In the stylish Condado district of San Juan, Comfort Inn San Juan features an outdoor pool, free Wi-Fi and a free buffet breakfast. The nearest beach is just a 5 minute drive away.
Score from 123 reviews Good
In Condado, Puerto Rico, this boutique hotel is just 1 block from Condado Beach and serves a daily continental breakfast. The hotel has free Wi-Fi in public areas and rooms with air conditioning.
Score from 327 reviews Good
La Concha Renaissance San Juan ResortWith an outdoor infinity pool overlooking Condado Beach, this 4-star resort features a 24-hour casino and several fine dining restaurants. The large guest rooms have private sea view balconies.
Score from 172 reviews Excellent
Most horrible experience. Checked out next day
The staff was friendly. The breakfast adequate and convenient.
The room was not clean. The shower was scummy. There was a piece of chewing gum on the floor when I got there. I left it there for one day thinking it was an oversight until I scraped it off the next day.
Loud traffic
I really enjoy the room and the quietness of the place. There were no loud noises or anything like that. The breakfast was amazing, everything from waffles and donuts to fresh coffee and juice
I have nothing bad to say except for the parking space. It is a little uncomfortable
Very peaceful...
Unsubscribe me, please!
The room needed renovation...dirty walls....broken furniture. ...out dated bathroom. One. Morning I was confronted by a large pit bull. ...I had to lock myself in a room near the lobby. ..finally staff came. They had no clear answer. I would not recommend or go to another one of your properties.
The view and stay were great!
The beach across the street was in much need of clearing up a lot of trash. Area could look better if it were kept up.
Very professional employees. Excellent customer care, friendly and respectful. Will gladly recommend the facilities.
Cable or antenna TV service had some kind of problems with the reception of some of the channels.
Clean comfortable spacious and fresh.
Breakfast food was good but the eating ware was plastic. It would have been perfect if plates and cups would have been plastic or ceramic. Other than that perfect!
I enjoy the beach and ocean view from the balcony, while cruise ships sail into Old San Juan. The location was 20 min. from the touristy areas of SJ but near some other nice and less crowed sites. I visit local Park attractions and seek out area history. Puerto Rican Restaurant across the street from CI, as well as the complimentary breakfast were excellent. Also, bilingual employees were friendly and eager to accommodate.
The only minus is the room size (tiny) and decor is dated.
What is not to like staff is excellent, food excellent
Staff was excellent
Limited option for restaurants. Restaurant at Comfort Inn not open during our stay
Excellent value for money paid, clean rooms, friendly and helpful staff. Will rebook at this hotel if I need to be in this area.
Shower stall a little small for large people, room should have better lighting, road traffic noise noticeable.
Staff was great trying to accommodate our needs
Rooms smelled moldy, old and torn furniture
We were very disappointed with this hotel as it is a part of the chain hotels. So we were thinking it would be on par with others we have stayed at in the US. The only positive we can say is the staff were wonderful.
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|By Business Wire
Article Rating:
|February 28, 2013 09:15 AM EST
ManageEngine, the real-time IT management company, today announced the general availability of the very first speech-driven mobile app for the IT help desk, the ServiceDesk Plus voice-enabled iPhone app. The app sets a new standard for help desk software, incorporating powerful speech recognition technology to let IT professionals manage the entire lifecycle of help desk incidents — from executing commands and dictating notes to assigning or closing out tickets. Previewed at Mobile World Congress 2013, the ServiceDesk Plus voice-enabled iPhone app is now available on the Apple App store via http://ow.ly/hT7hv. Also, a video demo of the ServiceDesk Plus iPhone app can be viewed at http://ow.ly/i79PD. Editions for other operating systems will follow later this year.
"Providing best-in-breed IT help desk support is a challenging task which requires a lot of organization, patience and employee time," said Craig Cameron, global IT project manager at ArjoHuntleigh (UK). "Our IT department was coming under increasing strain resulting from a growing number of support requests. This put added pressure on our antiquated ticket management process and created unnecessary stress for staff. The addition of an integrated voice recognition mobile app into ManageEngine ServiceDesk Plus means the team can now respond to tickets from any location, off any device, and without the need to type. This luxury feature saves my team immense amounts of time, enabling them to focus on other business critical IT projects."
Setting the New Help Desk Standard
Until now, the majority of IT help desk technicians have been glued to their desktop computers, troubleshooting and emailing end-users. A mobile app can free those technicians to handle trouble tickets from anywhere, anytime. But if the app does not offer speech recognition, the techs are forced to use tiny onscreen keyboards that can compromise productivity. With the voice-enabled ServiceDesk Plus mobile app, techs can forgo the keyboard and dictate their commands and notes — reducing frustration, improving productivity, and increasing customer satisfaction.
Incorporating proven speech recognition technology from Nuance Communications, Inc., the ServiceDesk Plus iPhone app provides an interactive, Siri-like user experience. It executes spoken commands and performs voice-to-text data entry, enabling users to:
- Dictate tickets
- Edit tickets
- Reply to tickets
- Assign/reassign
- Close tickets
In addition to the voice features above, the ServiceDesk Plus iPhone app includes a number of features that can be accessed via the iPhone touchscreen, enabling users to:
- Create new tickets, categorize, and edit request details
- Assign/pick up requests
- Reply to users with resolution and close tickets from the app
- Track time spent on tickets via WorkLog
- Perform searches based on subject, requester or priority
- Customize the request view
- Track the time spent on tickets using WorkLog
- Update the status of the requests
Pricing and Availability
The voice-enabled iPhone app for ServiceDesk Plus is available today, free of charge, from the Apple App Store via http://www.manageengine.com/products/service-desk/mobile-app.html. Support for additional mobile operating systems will be announced in the coming months.
For more information on ManageEngine ServiceDesk Plus, please visit http://www.manageengine.com/servicedeskplus. For more information on ManageEngine, visit http://www.manageengine.com; follow the company blog at http://blogs.manageengine.com, on Facebook at http://www.facebook.com/ManageEngine and on Twitter at @ManageEngine.
About ServiceDesk Plus
ManageEngine ServiceDesk Plus integrates help desk requests and assets for managing organizations' IT effectively. It helps to implement ITIL best practices and troubleshoot IT service requests faster. ServiceDesk Plus is highly customizable, easy-to-implement help desk software. More than 10,000 IT managers worldwide use ServiceDesk Plus to manage their IT help desk and assets. ServiceDesk Plus is available in 23 different languages. For more information about ManageEngine ServiceDesk Plus, visit www.manageengine.com/servicedeskplus.
About ManageEngine
ManageEngine delivers the real-time IT management tools that empower an IT team to meet an organization's need for real-time services and support. Worldwide, more than 70,000 established and emerging enterprises — including more than 60 percent of the Fortune 500 — rely on ManageEngine products to ensure the optimal performance of their critical IT infrastructure, including networks, servers, applications, desktops and more. ManageEngine is a division of Zoho Corp. with offices worldwide, including the United States, United Kingdom, India, Japan and China. For more information, please visit http://www.manageengine.com/; follow the company blog at http://blogs.manageengine.com/, on Facebook at http://www.facebook.com/ManageEngine and on Twitter at @ManageEngine.
ManageEngine is a trademark of Zoho Corp. All other brand names and product names are trademarks or registered trademarks of their respective companies.
Tags: ManageEngine, real-time IT, Zoho, ServiceDesk Plus, help desk, voice-enabled mobile app, iPhone, Siri, Nuance Communications, Nuance, mobile, application management, desktop management, virtualization, cloud, IT management, business service management, application performance monitoring, user experience monitoring, network management, server management
"We help companies that are using a lot of Software as a Service. We help companies manage and gain visibility into what people are using inside the company and decide to secure them or use standards to lock down or to embrace the adoption of SaaS inside the company," explained Scott Kriz, Co-founder and CEO of Bitium, in this SYS-CON.tv interview at 15th Cloud Expo, held Nov 4–6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Nov. 27, 2014 07:00 PM EST Reads: 1,821
15th Cloud Expo, which took place Nov. 4-6, 2014, at the Santa Clara Convention Center in Santa Clara, CA, expanded the conference content of @ThingsExpo, Big Data Expo, and DevOps Summit to include two developer events. IBM held a Bluemix Developer Playground on November 5 and ElasticBox held a Hackathon on November 6. Both events took place on the expo floor. The Bluemix Developer Playground, for developers of all levels, highlighted the ease of use of Bluemix, its services and functionalit...
Nov. 27, 2014 07:00 PM EST Reads: 1,844
Some developers believe that monitoring is a function of the operations team. Some operations teams firmly believe that monitoring the systems they maintain is sufficient to run the business successfully. Most of them are wrong. The complexity of today's applications have gone far and beyond the capabilities of "traditional" system-level monitoring tools and approaches and requires much broader knowledge of business and applications as a whole. The goal of DevOps is to connect all aspects of app...
Nov. 27, 2014 06:00 PM EST Reads: 1,622
The 4th International DevOps Summit, co-located with16th International Cloud Expo – being held June 9-11, 2015, at the Javits Center in New York City, NY – announces that its Call for Papers is now open. Born out of proven success in agile development, cloud computing, and process automation, DevOps is a macro trend you cannot afford to miss. From showcase success stories from early adopters and web-scale businesses, DevOps is expanding to organizations of all sizes, including the world's large...
Nov. 27, 2014 06:00 PM EST Reads: 2,289
SAP is delivering break-through innovation combined with fantastic user experience powered by the market-leading in-memory technology, SAP HANA. In his General Session at 15th Cloud Expo, Thorsten Leiduck, VP ISVs & Digital Commerce, SAP, discussed how SAP and partners provide cloud and hybrid cloud solutions as well as real-time Big Data offerings that help companies of all sizes and industries run better. SAP launched an application challenge to award the most innovative SAP HANA and SAP HANA...
Nov. 27, 2014 05:00 PM EST Reads: 1,665
When an enterprise builds a hybrid IaaS cloud connecting its data center to one or more public clouds, security is often a major topic along with the other challenges involved. Security is closely intertwined with the networking choices made for the hybrid cloud. Traditional networking approaches for building a hybrid cloud try to kludge together the enterprise infrastructure with the public cloud. Consequently this approach requires risky, deep "surgery" including changes to firewalls, subnets...
Nov. 27, 2014 04:45 PM EST Reads: 1,877
Want to enable self-service provisioning of application environments in minutes that mirror production? Can you automatically provide rich data with code-level detail back to the developers when issues occur in production? In his session at DevOps Summit, David Tesar, Microsoft Technical Evangelist on Microsoft Azure and DevOps, will discuss how to accomplish this and more utilizing technologies such as Microsoft Azure, Visual Studio online, and Application Insights in this demo-heavy session.
Nov. 27, 2014 04:45 PM EST Reads: 1,637
DevOps is all about agility. However, you don't want to be on a high-speed bus to nowhere. The right DevOps approach controls velocity with a tight feedback loop that not only consists of operational data but also incorporates business context. With a business context in the decision making, the right business priorities are incorporated, which results in a higher value creation. In his session at DevOps Summit, Todd Rader, Solutions Architect at AppDynamics, discussed key monitoring techniques...
Nov. 27, 2014 04:30 PM EST Reads: 1,783
Cultural, regulatory, environmental, political and economic (CREPE) conditions over the past decade are creating cross-industry solution spaces that require processes and technologies from both the Internet of Things (IoT), and Data Management and Analytics (DMA). These solution spaces are evolving into Sensor Analytics Ecosystems (SAE) that represent significant new opportunities for organizations of all types. Public Utilities throughout the world, providing electricity, natural gas and water,...
Nov. 27, 2014 04:00 PM EST Reads: 1,889
The security devil is always in the details of the attack: the ones you've endured, the ones you prepare yourself to fend off, and the ones that, you fear, will catch you completely unaware and defenseless. The Internet of Things (IoT) is nothing if not an endless proliferation of details. It's the vision of a world in which continuous Internet connectivity and addressability is embedded into a growing range of human artifacts, into the natural world, and even into our smartphones, appliances, a...
Nov. 27, 2014 04:00 PM EST Reads: 2,013
How do APIs and IoT relate? The answer is not as simple as merely adding an API on top of a dumb device, but rather about understanding the architectural patterns for implementing an IoT fabric. There are typically two or three trends: Exposing the device to a management framework Exposing that management framework to a business centric logic Exposing that business layer and data to end users. This last trend is the IoT stack, which involves a new shift in the separation of what stuff happe...
Nov. 27, 2014 03:00 PM EST Reads: 1,998
The 3rd International Internet of @ThingsExpo, co-located with the 16th International Cloud Expo - to be held June 9-11, 2015, at the Javits Center in New York City, NY - announces that its Call for Papers is now open. The Internet of Things (IoT) is the biggest idea since the creation of the Worldwide Web more than 20 years ago.
Nov. 27, 2014 03:00 PM EST Reads: 1,535
The Internet of Things is tied together with a thin strand that is known as time. Coincidentally, at the core of nearly all data analytics is a timestamp. When working with time series data there are a few core principles that everyone should consider, especially across datasets where time is the common boundary. In his session at Internet of @ThingsExpo, Jim Scott, Director of Enterprise Strategy & Architecture at MapR Technologies, discussed single-value, geo-spatial, and log time series dat...
Nov. 27, 2014 03:00 PM EST Reads: 2,171
An entirely new security model is needed for the Internet of Things, or is it? Can we save some old and tested controls for this new and different environment? In his session at @ThingsExpo, New York's at the Javits Center, Davi Ottenheimer, EMC Senior Director of Trust, reviewed hands-on lessons with IoT devices and reveal a new risk balance you might not expect. Davi Ottenheimer, EMC Senior Director of Trust, has more than nineteen years' experience managing global security operations and asse...
Nov. 27, 2014 01:00 PM EST Reads: 2,073
The Internet of Things will greatly expand the opportunities for data collection and new business models driven off of that data. In her session at @ThingsExpo, Esmeralda Swartz, CMO of MetraTech, discussed how for this to be effective you not only need to have infrastructure and operational models capable of utilizing this new phenomenon, but increasingly service providers will need to convince a skeptical public to participate. Get ready to show them the money!
Nov. 27, 2014 11:00 AM EST Reads: 1,872
SYS-CON Media announced that Centrify, a provider of unified identity management across cloud, mobile and data center environments that delivers single sign-on (SSO) for users and a simplified identity infrastructure for IT, has launched an ad campaign on Cloud Computing Journal. The ads focus on security: how an organization can successfully control privilege for all of the organization's identities to mitigate identity-related risk without slowing down the business, and how Centrify provides ...
Nov. 27, 2014 10:00 AM EST Reads: 1,757
The Internet of Things will put IT to its ultimate test by creating infinite new opportunities to digitize products and services, generate and analyze new data to improve customer satisfaction, and discover new ways to gain a competitive advantage across nearly every industry. In order to help corporate business units to capitalize on the rapidly evolving IoT opportunities, IT must stand up to a new set of challenges. In his session at @ThingsExpo, Jeff Kaplan, Managing Director of THINKstrateg...
Nov. 27, 2014 10:00 AM EST Reads: 1,897
"SAP had made a big transition into the cloud as we believe it has significant value for our customers, drives innovation and is easy to consume. When you look at the SAP portfolio, SAP HANA is the underlying platform and it powers all of our platforms and all of our analytics," explained Thorsten Leiduck, VP ISVs & Digital Commerce at SAP, in this SYS-CON.tv interview at 15th Cloud Expo, held Nov 4-6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Nov. 27, 2014 08:15 AM EST Reads: 1,627
One of the biggest challenges when developing connected devices is identifying user value and delivering it through successful user experiences. In his session at Internet of @ThingsExpo, Mike Kuniavsky, Principal Scientist, Innovation Services at PARC, described an IoT-specific approach to user experience design that combines approaches from interaction design, industrial design and service design to create experiences that go beyond simple connected gadgets to create lasting, multi-device exp...
Nov. 27, 2014 08:00 AM EST Reads: 1,849
Enthusiasm for the Internet of Things has reached an all-time high. In 2013 alone, venture capitalists spent more than $1 billion dollars investing in the IoT space. With "smart" appliances and devices, IoT covers wearable smart devices, cloud services to hardware companies. Nest, a Google company, detects temperatures inside homes and automatically adjusts it by tracking its user's habit. These technologies are quickly developing and with it come challenges such as bridging infrastructure gaps,...
Nov. 27, 2014 07:45 AM EST Reads: 2,010


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Pancreatic Chromatin Manipulation Generates New Insulin Producing Cells
By BiotechDaily International staff writers
Posted on 03 Mar 2013
Image: Treatment of human islets with the histone methyltransferase inhibitor Adox results in co-localization of the beta-cell specific transcription factor PDX1 (white) in a substantial subpopulation of glucagon-positive cells (red), indicating partial endocrine cell-fate conversion (Photo courtesy of Nuria Bramswig, Perelman School of Medicine, University of Pennsylvania).
Genomic researchers have created insulin-producing pancreatic beta cells through the selective enzymatic manipulation of the chromatin of glucagon-producing alpha cells.
Glucagon is a hormone secreted by alpha cells in the pancreas that raises blood glucose levels. Its effect is opposite that of beta cell insulin, which lowers blood glucose levels. The pancreas releases glucagon when glucose levels fall too low. Glucagon causes the liver to convert stored glycogen into glucose, which is released into the bloodstream. High blood glucose levels stimulate the release of insulin. Insulin allows glucose to be taken up and used by insulin-dependent tissues. Thus, glucagon and insulin are part of a feedback system that keeps blood glucose levels at a stable level.
Loss of beta cells and subsequent lack of insulin causes diabetes. One theoretical approach to correcting this problem is to convert some other cell type, such as alpha cells, into beta cells. To this end, investigators at the University of Pennsylvania (Philadelphia, USA) launched an in-depth study of the alpha and beta cell genomes.
They used ChIP sequencing and RNA sequencing analysis, to determine the epigenetic and transcriptional landscape of human pancreatic alpha, beta, and exocrine cells. ChIP sequencing is a method used to demonstrate the association between transcription factors or other DNA-binding proteins and specific regions of genomic DNA. Chromatin is isolated from preparations of nuclei, chemically cross-linked, and sheared to provide short fragments. Antibodies are used to immunoprecipitate the specific DNA-binding protein and with it, the fragment of DNA to which it is bound. Polymerase chain reaction (PCR) is then used to identify the presence of specific DNA fragments.
The investigators reported in the February 22, 2013, online edition of the
Journal of Clinical Investigation
that compared with exocrine and beta cells, differentiated alpha cells exhibited many more genes bivalently marked by activating and repressing histone modifications. Thousands of these genes were in a monovalent state in beta cells, carrying only the activating or repressing mark. Epigenomic findings suggested that alpha to beta cell reprogramming could be promoted by manipulating the histone methylation signature of human pancreatic islets.
Treatment of cultured pancreatic islets with a histone methyltransferase inhibitor led to co-localization of both glucagon and insulin and glucagon and insulin promoter factor 1 (PDX1) in human islets and co-localization of both glucagon and insulin in mouse islets. Therefore, mammalian pancreatic islet cells displayed cell-type–specific epigenomic plasticity, suggesting that epigenomic manipulation could provide a path to cell reprogramming and novel cell replacement-based therapies for diabetes.
"To some extent human alpha cells appear to be in a "plastic" epigenetic state," said senior author Dr. Klaus H. Kaestner, professor of genetics at the University of Pennsylvania. "We reasoned we might use that to reprogram alpha cells towards the beta-cell phenotype to produce these much-needed insulin-producing cells. We treated human islet cells with a chemical that inhibits a protein that puts methyl chemical groups on histones, which - among many other effects - leads to removal of some histone modifications that affect gene expression. We then found a high frequency of alpha cells that expressed beta-cell markers, and even produced some insulin, after drug treatment."
"This would be a win-win situation for diabetics," said Dr. Kaestner. "They would have more insulin-producing beta cells and there would be fewer glucagon-producing alpha cells."
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wow..this is a beautiful tribute to your father..
hope you shared this one with him..it is fabulous.. :) (Report) Reply
Jahan zaib
Loved to hear brave Hercules deeds,
Watched Superman for his flying traits,
Dreamed to be Spiderman for human needs,
Ironman merely against aggressive cats,
As childhood ceased mind got ease,
Hero changed and so did the dreams,
Romeo and Juliet started to please,
Riches and gold came through the beams,
In an age mature, there came a thought,
Looked all around, searched every corner,
In a single hero, Hero I sought,
Heroes my local and of the foreigner,
Had no powerful mighty flying wings,
No force to climb or hop like spider,
No extraordinary power no steel rings,
Neither was he a mythical ghost rider,
Beat of my heart, the sight of my eyes,
Father, my hero, reason of my rise.
Jahan zaib's Other Poems
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Comments about this poem (MY SUPERHERO by Jahan zaib )
* Sunprincess * (11/10/2012 1:04:00 AM)
wow..this is a beautiful tribute to your father..
The Reader (11/5/2012 10:11:00 AM)
a great write, a great tribute - my cords are touched as i missed my HERO 15 years back; 15 years back when i was nothing but a student he used to be glad on life's little achievements, my little things, i used to be a V.I.P when he was there. how tasteless it is to stand up yourself after falling down with the realization that your hero wont come to take care of you, how cruel it is to win laurels without his happy shouts.i wish to see him, to hear his voice, things are piled up for sharing, complaints are unheard, joys are staying in the phase of no-celebrations, sorrows die their natural death without catharsis, tears roll-down with no hopes of being wiped out by a kindred hands.i miss my super-hero. : ( (Report) Reply
Karen Sinclair (11/5/2012 5:07:00 AM)
Wonderful piece... first made me think of my lovely son who's hero at the moment is iron man but has been many different figures from buzz lightyear to spiderman but i was hoping that you were going to turn (as you indeed did) to a real role model in the end, one as you say cannot fly but as you see it let you be the success you are today by im guess grounded love and well thought out reactions...i also love that you titled this in capitals as it shows how important he is to you...tyvm (Report) Reply
Saeed Jan (11/3/2012 12:09:00 PM)
Superb one, with a flow like that of water.. all the lines contributing to make a greater whole with nothing superfluous.. what I like most in this poem is the changing heroes with changing time/age, but only one hero remains constant till the very end and that is father.... It hits me the most because U know my situation... Great write pal..! ! (Report) Reply
Raihana Abdul Jabbar (11/3/2012 10:26:00 AM)
Thanks a lot for your valuable comment on my poem.
This poem portrays a truth that everyone's real superhero is their father. Whatever they seek in childhood, teenage and in later stages of life, they will come back and emulate their father's footsteps when they meet a crisis in life. Awesome ink! Loved it... Allah Bless You! :) (Report) Reply
Yoonoos Peerbocus (11/3/2012 8:43:00 AM)
father my HERO-----both biological and spiritual------has other poetic layers too (Report) Reply
Payal Parande (11/2/2012 7:36:00 AM)
a wonderful piece by a wonderful person...may be you should look around more maybe you are someone's hero
i am pretty sure you are
thank you for sharing
payal (Report) Reply
Unwritten Soul (11/2/2012 6:14:00 AM)
Hahaha i loved it, humor and heroic action all in one write..this is great and i loved the spirit! ! _Soul (Report) Reply
Asif Andalib (11/1/2012 11:44:00 PM)
A wonderful tribute to your dear father. A lovely write (Report) Reply
Heyyou Boy (11/1/2012 3:36:00 PM)
We all have heros. Even though mans hero might be anothers villain. well done Jahan! (Report) Reply
Jahan Zeb (11/1/2012 11:10:00 AM)
My poem has got a trophy from Sir Thomas A Robinson and I really appreciate you Gulsher. (Report) Reply
Thomas A Robinson (11/1/2012 10:54:00 AM)
Yes Yahan our fathers are the everyday heros in our lives.I wish I could salute mine now. (Report) Reply
Gulsher John (11/1/2012 7:48:00 AM)
wow jaani.......assembled the whole Hollywood, nice treated the theme for different age instinct, this end note is superb.....Father, my hero, reason of my rise.
from comics to real world portrayed every Hero beautifully...... one humble request that be focused on rhyme and melody.............. good job (Report) Reply
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Please not only watch but VOTE to keep this great group on the show.
We LOVE Vocal Point and have all their CDs. They are incedible!
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These guys are off the hook. The real deal. Do something good and support these guys. Here's hoping you go all the way.... you deserve the best!
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We thought Noteworthy was great. Can't wait to hear Vocal Point tonight.
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You could tell VP just has so much performance experience than the other groups- they were just plain polished
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The Tennessee Wildlife Resources Agency provides several methods for hunters to report their big game harvests. Recently some hunters have reported problems when using their personal computer to report a harvest. TWRA is offering the following instructions for those persons experiencing time-out issues when accessing the TWRA's online harvest reporting system.
In most cases, the issues are connected to the internet browser on one's computer and can be resolved by following the steps below. (The specific instructions are based on Internet Explorer because it is the State of Tennessee standard). However, if a different browser is utilized such as Firefox or Chrome, the persons will need to accomplish the same task, but will need to refer to specific instructions posted on those manufacturer websites.
1) Select "Tools"
2) Select "Internet Options"
3) Delete all cookies and temporary internet files
4) Open a new browser tab and manually type in GOTWRA.ORG (do not use the saved link from a previous session)
Sportsmen are reminded that big game harvests can also be checked in on the TWRA mobile app from a smart phone or tablet and in person at a traditional check station. All bear harvests must be taken to an official TWRA checking station.
November 21, 2014
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