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Originally published April 10, 2007 at 12:00 AM | Page modified April 23, 2007 at 9:01 PM
Sun, Locker, shine on Dawgs
Maybe those were simply the winds of change whipping through Husky Stadium on Monday, at one point picking up some loose pages from a practice...
Seattle Times staff reporter
Maybe those were simply the winds of change whipping through Husky Stadium on Monday, at one point picking up some loose pages from a practice plan and lifting them in the direction of Lake Washington.
Because the first spring practice of 2007 for the Washington Huskies also served as the unofficial beginning of the Jake Locker era, the much-heralded quarterback from Ferndale who is finally off redshirt status.
He was tabbed as the team's No. 1 quarterback heading into drills in a news conference last Thursday, then took the reps with the starting unit in Monday's no-pads workout.
"I'm excited to see what he's going to do," said senior linebacker Dan Howell. "To see how he develops."
Locker, though, wasn't in much of a celebratory mood afterward, lamenting a few poor throws, including one that was picked off by linebacker E.J. Savannah.
"My overall goal is to be the number one guy when we get out of here," Locker said. "But the way I performed today, I've got to do better. I'm not worthy of that after how I played today, so I plan on going out the next couple of days and proving that I can be that guy."
UW coach Tyrone Willingham, however, thought Locker proved more than enough.
"It's clear he knows a lot more about the offense now than he did a year ago," Willingham said, adding that the several weeks late last season in the wake of the injury to Isaiah Stanback when Locker prepared as if he might play helped speed up his grasp of the playbook.
Locker also possesses some unique natural abilities that have excited UW fans since the day he committed in summer 2005. And those were on full display when he ran 77 yards for a touchdown on a simple read-option play in 11-on-11 drills.
There was no contact allowed in the practice, but no one would have gotten close enough to Locker to make a tackle if there had been as he outran the defense after sweeping around the end, then cutting back across the field.
"He's got wheels," marveled Howell.
And despite his dour assessment of his throwing, Locker put more than a few on the money, rebounding a couple plays after the interception to hit Marcel Reece from the near hash mark to the far sideline during a seven-on-seven drill.
Still, he mused that "I need to be more consistent and make my reads a little bit quicker."
Otherwise, it was a day of optimism as the Huskies began the third full season under Willingham, hoping to set a course for the program's first winning season and bowl game since 2002.
While the winds gusted, the sun shined throughout.
"The things that I'm looking for the first day are energy and effort and I thought that those two things were in place," said Willingham.
Particularly from Howell, whose bounding around the field would have put Richard Simmons to shame.
"It feels good to be back hitting and moving," he said. "We just want to let him [Willingham] know that we are going to go fast and go hard all the time."
With Locker having already ascended to the top of the quarterback depth chart, there aren't a lot of high-profile position battles, though some could emerge when the freshmen arrive in the fall.
In what could be one of the most hotly contested battles, Casey Bulyca ran ahead of Ryan Tolar at right guard in the competition to succeed Clay Walker.
The Huskies will practice without pads again today before getting into full pads later in the week. UW will conclude the spring with the annual Purple-White game April 28.
• There were no new injuries, and all of the players expected to participate did so. Only a few players were limited with minor ailments, most notably backup left tackle Eric Berglund, who sat out a few drills with a hamstring injury.
• Backup QB Carl Bonnell, still recovering from off-season surgery to his left (non-throwing) shoulder, took part in all the drills. However, he could be limited once the team puts on full pads. Bonnell said he has lost some weight off his listed 210 pounds in part because he wasn't able to do as much weightlifting due to the surgery.
Bob Condotta: 206-515-5699 or email@example.com. Read his blogs on Washington football and basketball at www.seattletimes.com/huskies.
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Returning Hajj pilgrims held up by delayed flightsHome-bound hajj pilgrims of Biman Bangladesh Airlines are suffering at Jeddah airport due to flight delays. Sources said Biman Bangladesh Airlines flights are experiencing delays by two to four hours at the airport, compounding the woes of the ... Dhaka Tribune, 1 month ago
Biman flights on sale! - Financial Express Bangladesh, 15 hours ago
Hajj flights start arriving - New Age Bangladesh, 1 month ago
4 images for biman bangladesh airlines
Biman board of directors meets in emergency meeting
The board of directors of Biman Bangladesh Airline sat in an emergency meeting Saturday evening in the wake of arrest of three top officials of the state-run airlines and two businessmen blessed by the board chairman in connection with gold ...New Age Bangladesh, 4 days ago BD Biman airline gold smugglers held Frontier Post, 1 week ago Bangladesh 'gold smugglers' arrested BBC, 1 week ago
Many Biman pilots, crews in panic
A large number of pilots and cabin crew of Biman Bangladesh Airlines are in panic following the arrest of four of their colleagues in connection with recent gold smuggling. A number of pilots and crew members said that they were over stressed ...New Age Bangladesh, 3 days ago Biman runs 10 aircrafts with 112 pilots, 2674 others manpower: Menon Bangladesh Sangbad Sangstha, 1 week ago 112 pilots operate 10 Biman aircrafts, Menon tells JS New Age Bangladesh, 1 week ago 112 pilots for operating 10 Biman aircrafts, Menon tells JS New Age Bangladesh, 1 week ago
5 Biman officials sent to jail
A Dhaka court has sent five officials of Biman Bangladesh Airlines to jail denying their bail petitions. The arrestees gave the confessional statement before the Dhaka Metropolitan Magistrate court on Sunday. After taking the statement, Md ...Dhaka Tribune, 3 days ago Top Biman officials detained New Age Bangladesh, 1 week ago 3 top Biman officials among five arrested Financial Express Bangladesh, 1 week ago Photo: DB of DMP presented before media five people Financial Express Bangladesh, 1 week ago
Bagladesh Airlines plans to start again domestic flight...
Bagladesh Airlines plans to start again domestic flights in January with Dash 8s Bangladesh Airlines plans to resume domestic flights in January, deploying two Dash 8-Q400s that it is sourcing from Egypt's Smart Aviation. "We are in ...Trans Reporter, 1 week ago Biman may resume domestic flights in January Bangladesh Daily Star, 2 weeks ago Biman Bangladesh to lease two Egyptian Q400s 4 Traders, 3 weeks ago Airlines reluctant to provide passenger info on Ebola New Age Bangladesh, 1 month ago
Biman picks up another foreign CEO
The failure on the part of Bangladeshi professionals in successfully running Biman Bangladesh Airlines led the authorities to hire another foreign aviation expert with high salary and benefits to make the national flag carrier profitable, officials ...New Age Bangladesh, 1 week ago Plight of Hajj pilgrims to be over in 5-6 days Financial Express Bangladesh, 1 month ago Menon asks Biman to remain alert in carrying hajj pilgrims Bangladesh Sangbad Sangstha, 1 month ago Airfare Monopoly Hurdles Bangladeshi Hajj IslamOnline NET, 1 month ago
New Biman MD joins Jan 1
Kyle Haywood, a South-African-born British citizen, will join Biman Bangladesh Airlines on next year's January 1 as the managing director and chief executive officer, said officials of the national flag carrier. Haywood, current MD of South ...Bangladesh Daily Star, 2 weeks ago Close Biman down Dhaka Tribune, 3 weeks ago Biman to drop Frankfurt, start fourth flight to London Dhaka Tribune, 1 month ago
40 gold bars recovered at Ctg airport
(BSS) - Customs officials recovered 40 gold bars weighing four and a half kilogram from a Biman Bangladesh Airlines flight at Chittagong Shah Amanat Airport this morning. The officials after their regular inspection found the gold bars fastened ...Bangladesh Sangbad Sangstha, 1 week ago Tk 20m gold seized at Shah Amanat Financial Express Bangladesh, 2 weeks ago Bangladesh smugglers trade gold for cows Nikkei Asian Review, 1 month ago Tk 29m gold bars seized from Biman flight at Ctg airport Financial Express Bangladesh, 2 months ago
Hajis may bring back 47kg of goods
From now, Hajj pilgrims can carry 47kg of goods instead of 30kg on the return flights of Biman Bangladesh Airlines, said a civil aviation and tourism ministry press release yesterday. Minister Rashed Khan Menon, now in Makkah, has made the ...Bangladesh Daily Star, 1 month ago Hajj pilgrims now can carry 47kg of goods on return flights Bangladesh Daily Star, 1 month ago Hajis can carry 47kg goods on Biman return flights Financial Express Bangladesh, 1 month ago Hajj pilgrim can carry 47 kg in return flight Dhaka Tribune, 1 month ago
416 Hajis return home in first batch
:00:00 A A- A+ FE Report The first return Hajj flight of Biman Bangladesh Airlines carrying 416 Hajis arrived at Hazrat Shahjalal International Airport (HSIA) at 02:35pm Thursday. Chairman of Civil Aviation Authority, Managing Director of ...Financial Express Bangladesh, 1 month ago First return hajj flight arrives Dhaka Tribune, 1 month ago First hajj flight returns Bangladesh Daily Star, 1 month ago Hajis to fly back home from today Financial Express Bangladesh, 1 month ago
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"Self destruct in 30 seconds" said the computer. "Guys, what if we cut the door open with a lightsaber?" Yoda said. Slek and Kyo followed Yoda to the door. They all got close to the door and cut mini doors for them to fit in. "5 seconds" said the computer. They now could get out. "2" said the computer. they jumped out quickly. BOOOOOOM! the explosion pushed them foward, but also hurt them. They fell down the mountain and landed on the ground. They jumped back when they noticed there was a avalanche. Rocks fell down. The rocks scattered all around the ground. They sliced all the rocks in their way. A big boulder about 10x bigger then Kyo rolled to them. They ran. Then there was a big pile of bricks, from there, it looked like a broken village. "It's a village, lets get to it!" Slek said. Yoda and Kyo followed Slek. They ran to the village. Then they looked behind them, the boulder stopped! "We're safe!" all of them said. They got to the village, and it was just a pile of bricks from a village.. Kyo said, "What if I built a speeder?" Kyo used the force to put the bricks together. The bricks went into a speeder. it had 3 cannons, 2 rocket launchers, and 3 seats. Kyo, Slek, and Yoda all jumped in the seats. They rode off to find the HQ. To Be Continued..
Do you love the republic? Do you hate droids? Do you like space battles and boarding ships and airborne jumps? If you do, this is the club for you! Join the CTPC!!! Look at my most recent CTPC creati …
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Chewbacca is meeting with some Ewoks to discuss a sneak attack.
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Open every day of the year
Winter Hours (Nov 1 - Feb 28)
Admissions Open 10 a.m. to 4 p.m.
Grounds close at 5 p.m.
Ages 12-64: $13
Ages 65+: $11
Ages 3-11: $9
2 and Under: Free
2014 Free Days: 11/3, 11/14, 11/20
Denver Zoo guests may see some stumbling stripes in the Grevy's zebra yard. On the morning of August 19, Denver Zoo welcomed the birth of an endangered, Grevy's (Greh-veez) zebra. At just over a day old the unnamed foal, whose gender is still not known, is still trying to figure out how to use its long, wobbly legs and rarely ventures more than a few feet away from its mother, Crestone. Guests can see mom and foal with the entire herd in the yard now.


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CHICAGO – The awesomeness of history loses any of its stuffiness with the incredibly fun, indeed educational show "Drunk History" from Comedy Central, its two seasons now released on DVD. Hosted by its creator Derek Waters, the show is a celebration of various historic figures and their under-appreciated true tales, as expressed by funny people narrating in the universal language of inebriation; their recounts are then reenacted by famous actors working with their given dialogue, dressed with the comic cheapness of a bloated biopic.
Film News: 2013 Independent Spirit Award Nominations Announced
CHICAGO – Two acclaimed crowd-pleasers led the nominees for the 2013 Independent Spirit Awards, which were announced November 27th. The quirky ensemble comedies "Silver Linings Playbook" and "Moonrise Kingdom" snagged five nominations apiece. The latter picture recently garnered a Best Feature accolade from the Gotham Independent Film Awards.
At the Indie Spirit Awards, David O. Russell's "Playbook" and Wes Anderson's "Kingdom" were joined in the Best Feature category by Ira Sachs' "Keep the Lights On," Richard Linklater's "Bernie" and Benh Zeitlin's "Beasts of the Southern Wild." All of the directors whose films were nominated in the top category also received Best Director nominations, with the exception of Linklater, who was replaced by Julia Loktev ("The Loneliest Planet"). Earning nominations for Best First Feature were Rama Burshtein's "Fill the Void," Adam Leon's "Gimmie the Loot," Colin Trevorrow's "Safety Not Guaranteed," Zal Batmanglij's "Sound of my Voice" and Stephen Chbosky's "The Perks of Being a Wallflower." Only "Fill the Void" and "Safety Not Guaranteed" also received Best First Screenplay nominations alongside "Robot & Frank," "Celeste and Jesse Forever" and "Gayby." Oddly missing from the category was Zoe Kazan, whose rookie screenplay for "Ruby Sparks" scored a Best Screenplay nomination alongside "Moonrise Kingdom," "Silver Linings Playbook," "Keep the Lights On" and "Seven Psychopaths."
Bill Murray, Tilda Swinton, Bruce Willis, Edward Norton and Frances McDormand star in Wes Anderson's Moonrise Kingdom.
Photo credit: Focus Features
The Best Male Lead category was expanded to six nominees in order to fit Jack Black ("Bernie"), Bradley Cooper ("Silver Linings Playbook"), John Hawkes ("The Sessions"), Thure Lindhardt ("Keep the Lights On"), Matthew McConaughey ("Killer Joe") and Wendell Pierce ("Four"). Rounding out the Best Female Lead category were Linda Cardellini ("Return"), Emayatzy Corinealdi ("Middle of Nowhere"), Jennifer Lawrence ("Silver Linings Playbook"), Quvenzhané Wallis ("Beasts of the Southern Wild") and Mary Elizabeth Winstead ("Smashed"). McConaughey also scored a Best Supporting Male nomination (for "Magic Mike") along with David Oyelowo ("Middle of Nowhere"), Michael Péna ("End of Watch"), Sam Rockwell ("Seven Psychopaths") and Bruce Willis ("Moonrise Kingdom"). For Best Supporting Female, Rosemarie DeWitt garnered a well-deserved nomination for her work in "Your Sister's Sister," joining Ann Dowd ("Compliance"), Helen Hunt ("The Sessions"), Brit Marling ("Sound of my Voice") and Lorraine Toussaint ("Middle of Nowhere").
Ben Richardson's hugely praised cinematography for "Beasts of the Southern Wild" predictably received a nomination alongside "Valley of Saints," "Here," "End of Watch" and "Moonrise Kingdom." After winning the Best Documentary award at the Gotham ceremony, "How to Survive a Plague" was nominated in the same category at the Spirit Awards. Joining it were "Marina Abramović: The Artist is Present," "The Central Park Five," "The Invisible War" and "The Waiting Room." Michael Haneke's widely revered Palme d'Or winner, "Amour," was included in the Best International Film category with "Once Upon a Time in Anatolia," "Rust and Bone," "Sister" and "War Witch."
Nominees for the Piaget Producers Award were "Nobody Walks," "Prince Avalanche" and "Stones in the Sun." The Someone to Watch Award favored "Pincus," "Gimmie the Loot" and "Electrick Children," while the Truer Than Fiction Award highlighted emerging documentary filmmakers Lucien Castaing-Taylor and Véréna Paravel ("Leviathan"), Jason Tippet and Elizabeth Mims ("Only the Young") and Peter Nicks ("The Waiting Room"). Sean Baker's critical darling, "Starlet," was honored with the Robert Altman Award for ensemble acting, as well as a nomination for the John Cassavetes Award. The accolade singles out feature films made for under $500,000. The other nominees were "Breakfast with Curtis," "Middle of Nowhere," "Mosquita y Mari" and "The Color Wheel."
By MATT FAGERHOLM
oh. sorry to hear about
oh. sorry to hear about Linklater's snub.
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(This story first ran at PressConnects.com) BALTIMORE — At 26 years old, UFC light-heavyweight champion Jon Jones admits it is difficult even for him to realize he could soon be considered the best fighter in the history of mixed martial arts. But it's a reality (…)
RIO DE JANEIRO -- Tony Martin discussed getting back on track at UFC 179 with a win over Fabricio Camoes, dealing with the hostile atmosphere, the kimura finish, and much more. read news >>
MMA Fighting's Ariel Helwani and Guilherme Cruz look back at UFC 179: Aldo vs. Mendes 2. read news >>
A roster spot in the highly-competitive Ultimate Fighting Championship (UFC) middleweight division has opened up after Tor Troeng has decided to walk away from mixed martial arts (MMA) after sufferin read news >>
It's safe to assume former UFC middleweight champion and MMA great Anderson Silva will wrap up his career with the UFC.Filed under: Featured, News, UFC read news >>
UFC 179 didn't feature many ranked fighters, but the light heavyweight division experienced a shake-up following Phil Davis' win against Glover Teixeira. It may come as a surprise to many but UFC 179 read news >>
Diego Sanchez discusses the injury that forced him out of UFC 180. read news >>
Eddie Alvarez looks back at his UFC debut and ahead to what's next. read news >>
Kid Nate is joined by Eugene S. Robinson and Dallas Winston for a discussion of the epic UFC 179 title fight and what's next for champ Jose Aldo. read news >>
Former UFC middleweight champion Anderson Silva was hospitalized on Monday with severe back pain. In sudden and dramatic fashion, Anderson Silva found himself hospitalized with severe back pain follo read news >>


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Custom Recipes for
Rosemary Pasta in Roasted Garlic Sauce
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New Music
Watch the New EP Trailer for Team Spirit's Self-Titled Debut
Peep this lighthearted EP trailer from VICE fam Team Spirit, the new project (that we've already told you all about because we <3 them) from former Passion Pit synth wizard Ayad Al Adhamy, featuring animation from Swedish duo Hannes and Johannes. Adhamy's new gig finds him discarding emotive electronics in favor of crunchy garage rawk, guitars and all. Team Spirit's self-titled EP drops April 9th on VICE Records, and will be complemented by a series of videos for each of its songs (à la MJ's Moonwalker). The band will also embark on a brief tour with The Joy Formidable in mid-April. Check the dates below:
04.12 - Phoenix Concert Theatre - Toronto, ON
04.13 - Théâtre Corona Virgin Mobile - Montreal, QC
04.14 - Upstate Concert Hall - Albany, NY
And if you're heading down to ATX next week, be sure to catch Team Spirit at one of these shows:
Watch Beyonce's Video for "7/11," Which Is the Ultimate Selfie
Jock Club is Destruction Unit's Best Kept Deep House Secret, So Stream the 'After Hours' LP
Get Your "Holidays" Off to a Good Start with This Beautiful Song and Video by The Lonely Wild
Listen to T-Pain's "Coming Home," His Auto-Tune Tribute to the Troops


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How do I change the language of Google Chrome from Hebrew to English ?
I have a PC with Windows operating system. I do not know how to find out which revision of Windows.I tried to change the language by going through settings in Google, but was unsuccessful.
1 Answer
This might help >>http://productforums.google.com/forum/#!topic/chrome/qLIN6yyQBtk
|1 year ago. Rating: 2
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Richard Dean doesn't like to talk about supply chains. He prefers supply chain network, community or ecosystem.
"The world does not work like a chain. It works like a community," said Dean, chief marketing officer at cloud-based software vendor One Network. "The chain metaphor suggests sequential links. In a community, the members work together for individual and mutual benefit."
This interconnectedness is reflected in One Network's cloud-based supply chain network, which allows trading partners to share and monitor information with each other and their partners and connections, and to synchronize business processes and events from point of sale to raw materials sourcing.
One Network has partnered with the University of North Texas on a research project that seeks to expand the understanding of how companies can leverage real-time information on demand to determine their "theoretical minimum inventory" — the smallest stockpiles they can maintain without jeopardizing service or sacrificing sales growth.
It's a potentially groundbreaking project with an ambitious goal: "to determine the theoretical minimum inventories in any supply chain ecosystem, presuming all information latency is eliminated, while asset availability and performance are optimized."
Information latency is the lag in communicating information through supply networks. "We differentiate between physical and informational lead time," Dean said. "Once you take out the information latency, you can take out more physical lead time. That takes you to your theoretical inventory minimums."
Don't be put off by the word "theoretical." This research has solid dollars-and-cents relevance, said Wesley Randall, assistant professor of logistics at North Texas and leader of the research effort. "It's very real," he said. "There's a tremendous amount of waste in supply chains. If companies can get real-time data that is actionable and allows them to understand their true minimum inventory levels, it could be a game-changer."
Companies have long touted just-in-time supply chains' role in minimizing inventory, but One Network CEO Greg Brady says there's much to be done. "Despite all the major technology investments over the past 20 years, supply chain performance has failed to measurably improve, and in many cases has gotten worse. Even the best supply chains still operate with massive amounts of inventory," Brady said when the research project was announced last spring. "The results of this research will bring into sharp focus the causes of this stagnation and more importantly, what can be done about it."
The University of North Texas research into theoretical minimum inventory is related to what One Network does for companies such as Del Monte Foods.
Using the computer cloud, One Network captures details on lead times, manufacturing frequency, batch sizes, ordering policies and other data that are crunched by algorithms and demand signals to automatically adjust inventories at each level of partners' supply chain networks.
For example, if a retailer expects to sell a certain number of lawnmowers, the information is shared not only with the supplier and manufacturer but also with their suppliers — and in a format they can use. Retail orders for 1,000 lawnmowers are translated into orders that tell suppliers the exact number of nuts, bolts and carburetors that will be needed and when they're needed.
Squeezing out information latency allows partners in the supply network to base decisions on actual demand instead of forecasts, Dean said. "All forecasts contain errors," he said.
In a retailer's typical supply chain, a point-of-sale forecast is passed upstream to a series of vendors and suppliers, each of which makes its own forecast. Inevitably, forecast errors are introduced at each step, and are magnified by delays. By the time the information reaches the start of the supply chain, it's a classic "bullwhip" effect.
To hedge against uncertainty, companies build more inventory than they'd need if they knew exactly what and when their customer would need it.
The University of North Texas research couples software such as One Network's with an algorithm that quantifies the time needed to transmit relevant information throughout a supply chain network. The idea is to help companies leverage up-to-the-minute information to determine how close they want to come to theoretical minimum inventory.
"We're taking software that is almost agnostic, coupled with a thought process," Randall said. The software prompts a series of questions: What's the demand? Variance of demand? Lead time? Standard deviation? The answers, coupled with the software solution, "allow you to see in very high fidelity the results of your supply chain processes."
Some companies may decide that they'd rather spend more on inventory to ensure good customer service or to increase chances for future sales. But at least they'll understand the tradeoffs involved, Randall said.
Cloud-based software makes it possible "to quantify the current inventory versus the theoretical minimum inventory, and to translate that into dollar signs," Randall said. "That is very powerful at the CEO and CFO level."
Randall's North Texas team includes specialists in logistics, marketing, information technology and decision sciences. Their research so far has been based on companies' information and observations. The next step would be to develop additional data that would allow researchers to develop a basic theorem that companies can use to determine their theoretical minimum inventories.
"We'd like to use these numbers to find out whether there are some large-scale relationships in the corporate data that we could gain some insight from," Randall said. "If you assume real-time access to data and then you bring in this idea of theoretical minimums, you can see how much inventory you can pull out of your supply chain. From our perspective, it's a lot."
Contact Joseph Bonney at email@example.com and follow him at twitter.com/JosephBonney.


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Munters Interim Report January-June 2003
STOCKHOLM, August 18, 2003 (PRIMEZONE) -- Munters announces Interim Report (Other OTC:MUNTF)
DRD Joins Prestigious Philadephia Gold Index
JOHANNESBURG, South Africa, Aug. 18, 2003 (PRIMEZONE) -- With effect from today, the shares of South African gold producer, Durban Roodepoort Deep, Ltd. "DRD" (JSE:DUR) (Nasdaq:DROOY) (LSE:DURJq) have been included as a constituent of the benchmark Philadelphia Gold and Silver Index (the XAU).
DRD and NUM Reach 24-Month Wage Settlement
JOHANNESBURG, South Africa, Aug. 18, 2003 (PRIMEZONE) -- Gold miner Durban Roodepoort Deep, Limited (DRD) (Nasdaq:DROOY) (LSE:DURJq) today (August 18, 2003) reached agreement on a 24-month wage deal with the National Union of Mineworkers (NUM) and flagged its intention to introduce an employee equity participation scheme.
LifePoint, Inc. Invites You to Join its First Quarter Fiscal 2004 Conference Call
ONTARIO, Calif., August 18, 2003 (PRIMEZONE) -- LifePoint, Inc. (AMEX: LFP), announced that in conjunction with the Company's fiscal 2004 first quarter earnings release, you are invited to listen to its conference call on Wednesday, August 20, 2003 at 4:30 p.m., EST (1:30 p.m. PST), with Linda H. Masterson, President and CEO and Don Rutherford, Vice President and CFO. The financial results for the first quarter FY 2004 ended June 30, 2003 will be reported on August 19, 2003.
Financial Executives International
Los Angeles Chapter of Financial Executives International Continues Summer Speaker Series in August
LOS ANGELES, August 18, 2003 (PRIMEZONE) -- The Los Angeles Chapter of Financial Executives International (FEI) today announced that its summer speaker series will continue on August 21, 2003, at three different locations in the Los Angeles area. The programs start at 4 p.m. and the schedule is as follows:
Valley Bank Earnings Up in 2nd Quarter
MORENO VALLEY, Calif. Aug. 18, 2003 (PRIMEZONE) -- Valley Bank (OTCBB:VMOY) said an increase in core earnings in the second quarter helps boost profitability.
Photo Release -- Huddle House Celebrates First Opening in West Virginia
DECATUR, Ga., Aug. 18, 2003 (PRIMEZONE) -- Huddle House Inc., a 24-hour, full-service family dining restaurant chain, today announced the opening of its first restaurant in West Virginia in the town of Chapmanville. The new restaurant, the fifth of 32 Huddle House restaurants to be built nationwide this year, opened for business on Aug. 11, 2003 and is located at One Central Avenue at the intersection of Highway 119, adjacent to the Best Western hotel.
Global ePoint Announces Signing of New Corporate Customers; Receives Initial Orders to be Delivered in the 2003 Third Quarter Totaling Approximately $500,000 in Additional Revenue
CITY OF INDUSTRY, Calif., Aug. 18, 2003 (PRIMEZONE) -- Global ePoint, Inc. (the "Company") (Nasdaq:GEPT) today announced that its recently acquired McDigit division ("McDigit"), which manufactures customized computers and provides comprehensive solutions for industrial personal computer, commercial personal computer and contract manufacturing markets, has signed two new corporate customers. Under the arrangements with the new customers, McDigit will be providing industrial personal computers to the customers for use with the customers' advanced security technology. The relationships are expected to be ongoing, and the customers have initially ordered approximately $500,000 of industrial personal computers to be fully delivered in the 2003 third quarter. Although there can be no certainties to continuing orders, it is anticipated that the customers could order $400,000 to $800,000 of industrial personal computers per month once the initial orders are delivered, potentially providing approximately $5 million to $10 million of additional annual revenue over the next year.
Stockwinners.com Option Picks Average Gains of More than One Hundred Percent; Rumors Up Twenty-Three Percent
AUSTIN, Texas, August 18, 2003 (PRIMEZONE) -- The following is an investment opinion issued by Stockwinners.com.
Ahold announces General Shareholders' Meeting
ZAANDAM, The Netherlands, August 18, 2003 (PRIMEZONE) -- After consultation with the VEB (Dutch Association of Securities Owners), Ahold (NYSE:AHO) announces a General Shareholders' Meeting, to be held on Thursday, September 4, 2003 at 10:00 a.m. at the Fortis Circustheater in The Hague.


text:
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University of Cambridge > Talks.cam > Wednesday Lunch Time Seminar Series > Mental health and mental imagery: from experimental psychopathology to treatment innovation
Mental health and mental imagery: from experimental psychopathology to treatment innovation
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Other talksDoing Social Research with Social Media: The Question of Participation Reporting and writing on EU Affairs in times of crisis The Making of Measurement Building a Climate System Laboratory: Modelling the climate system. CGHR Research Group: What is being targeted when women become the victims of anti-Muslim hate crime? Religion, or gender, or both? The real reach of the constructible universe


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united states
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|Live Scores
|Video & Audio
The Bulletin by Sriram Veera
July 20, 2009
Bangladesh 232 (Rahim 48, Raqibul 44, Roach 6-48) and 217 for 6 (Shakib 96*, Raqibul 65, Sammy 5-55) beat West Indies 237 (Dowlin 95, Richards 69) and 209 (Bernard 69, Shakib 5-70) by four wickets
Scorecard and ball-by-ball details
How they were out
Related Links
News : This is our biggest achievement - Shakib
Players/Officials: Raqibul Hasan | Darren Sammy | Shakib Al Hasan
Series/Tournaments: Bangladesh tour of West Indies
Teams: Bangladesh | West Indies
Set a target of 215, a counterattacking Raqibul, who had walked in at 29 for 2, was joined by Shakib at 67 for 4 and the pair batted bravely to seize back the initiative. Though Sammy took out Raqibul and Mushfiqur Rahim, 14 runs away from the win, Shakib held his nerve to steer the team home. The winning moment came at 5.38 pm and in some style, with Shakib lofting Kemar Roach over long-on.
Though Raqibul fell 42 runs short of the target, it was he who had set up the win with an inspired performance. He had never hit a Test fifty before and he had struggled in the first Test due to his penchant of playing away from the body. However, he had held his own in the first innings here and added a dash of bravado today to lift Bangladesh from a hole. It was a gem of a cameo under the circumstances. Every time West Indies picked up a wicket and threatened to charge ahead, Raqibul counterattacked to keep the hosts on their toes. He chose to take the adventurous route and didn't waste a single run-scoring opportunity; in fact he created a few chances of his own.
It was risky at times but someone had to seize the initiative back from West Indies and Raqibul decided to shoulder that burden. Apart from Sammy's superb spell, Raqibul's battle against Roach was the highlight of the session. Roach v Raqibul was the turning point in the first innings as Roach successfully probed a weakness in Raqibul against the bouncers before proceeding to scythe through the rest of the line-up. Raqibul was in no mood to buckle down today.
He started with a fierce slash over point and remained audacious against anything that was pitched up to him. It was a tantalizing battle as Roach troubled him a bit with short-pitched deliveries and a couple of jaffas that left the bat late but Raqibul released the pressure with a couple of impish square drives. He flicked Sammy and guided him through to third man boundary and thus, preventing West Indies from deploying close-in fielders. And when Ryan Austin, the offspinner, was brought in for the over before tea, Raqibul dispatched him over deep midwicket and in the last session, he unfurled a couple of peachy off drives to further calm the dressing-room nerves.
Thankfully, for Bangladesh, Raqibul found a willing partner in his captain Shakib, who too oozed intent through his knock. He started off a touch shakily with a stab past second slip, an airy drive past mid-off, and an edge past gully but soon settled down to blunt the attack. Now and then, he teased the slip cordon with his slashes but just when it appeared he was living on the edge, he would unfurl a meaty off drive, defend solidly or steal a single to frustrate the attack.
Shakib took on the dominating role in the final session, spanking boundaries almost at will, including a hat-trick of fours against Roach. The first one, an extra-cover drive that brought up his fifty, was followed by a crunching cut and a feisty pull as Bangladesh galloped towards victory. If the final session was almost serene, the second was a dramatic and event-filled. The day had started with a two-hour rain delay and Bangladesh took just 4.1 overs to wrap up West Indies for 209; it was the first time Bangladesh had bowled out the opposition for less than 250 in both innings.
Till Raqibul and Shakib took the bowling on, it was Sammy who stole the show. Every one knows that Sammy is not going to blow the opposition away; his is a gentle art. He builds pressure with a cluster of seaming deliveries in the corridor outside off and gently nudges the batsmen into making a mistake. Bangladesh initially stumbled into making fatal mistakes under the pressure of the chase and perhaps, under the strain of making history.
Sammy struck in his very first over, inducing Tamim Iqbal into edging a delivery leaving him before turning his attention to Junaid Siddique. After bowling 14 deliveries - most of them in the off-stump channel - for just one run, he got the next one to curve away from the middle and off line and Siddique tried to flick it rather injudiciously across the line but edged it low to first slip where Floyd Reifer took a sharp catch. Sammy then produced a gem to take out Mohammad Ashraful, who has gifted his wicket previously in the series but was unlucky to get a very good delivery that shaped away from him very late.
Sammy was supported well by Roach, who was the chief tormentor of Bangladesh. Roach, who surprisingly didn't take the new ball, was introduced in the second session and immediately looked menacing with his cocktail of bouncers and full deliveries outside off stump. He followed a lifting delivery with the one angling away to coax Imrul Keyes into edging to slip where Sammy took a brilliant catch, leaping at second slip.
For a brief while, when Roach and Sammy operated in tandem, the game appeared to be hanging in balance but Shakib and Raqibul ensured their fans won't lose too much hair or nails.
Pakistan should not welcome Amir back
The serene team culture cultivated by Misbah and his men shouldn't be allowed to be disrupted by a player with a tainted past
November games need November prices
An early start to the international season, coupled with costly tickets, have kept the Australian public away from the cricket
In 2011, MS Dhoni helped end a 28-year wait for India and gifted Sachin Tendulkar something he had craved throughout his career - to be called a World Cup champion
Coloured clothes, black sightscreens, two white balls: the game of cricket looked so different in 1992. But writing about it now seems more fun than watching it then
The inherent dangers of batting
The sickening blow that struck Phillip Hughes is a reminder of the ever-present dangers associated with facing fast bowlers, even while wearing a helmet
November games need November prices (85)
An early start to the international season, coupled with costly tickets, have kept the Australian public away from the cricket
The inherent dangers of batting (42)
The sickening blow that struck Phillip Hughes is a reminder of the ever-present dangers associated with facing fast bowlers, even while wearing a helmet
A crisis that defines the age (40)
Never mind cricket's absence from free-to-air TV - changes in social attitudes, the demands of work, and an individualistic age are all contributing to a decline in participation
Misbah's Pakistan or Imran's Pakistan? (38)
Pakistan have notched up some fine wins under Misbah-ul-Haq's leadership, but they haven't yet achieved consistent results outside the UAE
Why the Indian opener would be well advised to shelve the hook and pull in Australia


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About our kids Mom - Today's Christian Videos
Embed hollyorganizer 1283 views 2010-10-02T01:27:11 So need to remember this every single day, you don't know what tomorrow will bring
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- 32 total posts
- 1 review
- 31 comments
Reviews by aflatterme
36 Year Old with 4 Kids, TT with Lipo to Abdomen, Flanks & Lower Back - Mokena, IL
My first child was born 8 years ago, 2 years later had another and 2 years after that had twins for a total of 4 children. This mama ain't having anymore. I love my family more than life itself, but my pregnancies wreaked havoc on my stomach and I have photos to prove it! I never imagined I... READ MORE
Recent comments from aflatterme
I totally agree with you & I think you have done everything humanly possible! Good Luck! READ COMMENT
Good Luck! I am looking forward to hearing about your recovery! I am scheduled next Tuesday (12-2) & feel way behind after reading your blog:) Thanks for keeping me on my toes ;) READ COMMENT
Looks great! Hope your feeling well! READ COMMENT
Good Luck! I am scheduled for Tuesday, December 2nd. I loved reading your updates! Continue to keep updating :) xoxo I am getting so nervous :/ READ COMMENT
Good luck tomorrow! My thoughts will be with you & look forward to hearing about your recovery! xoxo READ COMMENT


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Explore the holiday program offerings from WVIZ/PBS and 90.3 WCPN ideastream below.
Gerald Freedman, Paula Vogel and Neil Gaiman
The Sound of Applause: 2:00 PM on 90.3 WCPN
Dee Perry shares her interview with former artist director for Great Lakes Theater Gerald Freedman the creator of Great Lakes' A Christmas Carol production. Plus Dee welcomes Pulitzer-Prize winning playwright Paula Vogel to preview Dobama Theater's production of A Civil War Christmas. And Dan Polletta talks with author Neil Gaiman and his wife Amanda Palmer about the art of the audio book.
Chanukah in Story and Song
9:00 PM on 90.3 WCPN
Narrated by Leonard Nimoy and sung by the acclaimed vocal sextet The Western Wind Vocal Ensemble, "Chanukah in Story and Song" is a unique holiday program created especially for public radio listeners.
This delightfully engaging program presents 25 eclectic selections, from the Ladino songs of the Spanish Jews and Yiddish melodies of Eastern Europe to modern Israeli tunes and the ensemble's original version of "I Have a Little Dreydle."
The ensemble performs a cappella as well as with instrumental accompaniment. The narration, written by Rabbi Gerald Skolnik, sheds new light on the holiday's customs and rituals. Listeners of all ages will hum the tunes after enjoying this wonderful program.
Hanukkah Lights 2014
10:00 PM on 90.3 WCPN
A perennial NPR favorite with brand new Hanukkah stories written by acclaimed authors Debra Ginsberg, Anne Burt, Simone Zelitch, Andrew Borowitz, and Theodore Bikel. Hear a wide variety of stories perfect for the holiday --- one story is funny and crisp, another historical, and there's one with a multicultural theme. Also included is a story about the supernatural and one that ends with the best last line for any Hanukkah show, "Love is the only miracle." Hosted by Susan Stamberg and Murray Horwitz.
A Paul Winter Solstice 2014
10:00 PM on 90.3 WCPN
Celebrate the return of the sun and the warming of the heart with Paul Winter's All New 34th Winter Solstice Celebration. On the darkest night of the year, we head back to New York's Cathedral of St. John the Divine to hear The Paul Winter Consort and the glorious Cathedral Pipe Organ. The performance brings traditional holiday favorites and new sounds from around the world with special guests Ivan Lins and Renato Braz. Hosted by John Schaefer.
Ivan Lins has moved audiences with his Latin Grammy-winning compositions for over 30 years. His music has been performed and interpreted by countless artists, including icons like Ella Fitzgerald, Barbara Streisand, and Quincy Jones. Lins joins Winter in St. John The Divine's to mark the Solstice in song.
Renato Braz began to sing at five. He spent his teens playing the bars of Sao Paulo. Braz's four solo albums in the past two decades have established him as great world vocalist and remarkable songwriter. This year he takes the Solstice stage with Paul Winter to perform his own achingly beautiful compositions, some Solstice favorites, and songs of iconic Brazilian songwriter Ivan Lins, alongside Lins, gospel singer Theresa Thomason, The Paul Winter Consort, and a Brazilian chorus.
Tinsel Tales: NPR Christmas Favorites
9:00 PM on 90.3 WCPN
This program features stories from the NPR archives that touch on the meaning of Christmas. David Sedaris, Bailey White, John Henry Faulk—these and other NPR voices, past and present, tell stories of the season. Hosted by Lynn Neary.
Featured Stories:
Dad 'n' Sam (Jay Allison)
Homeless Christmas (Lee Stringer)
Christmas Morning, 1949 (Sylvia Seymour/Paul Auster)
Low-Glamour Christmas Party (Bailey White)
Doing it in the Closet (John McIlwraith)
Christopher (Jay O'Callahan)
Ode to Christmas (Chuck Kramer)
Santaland Diaries (David Sedaris)
Modern Day Joseph and Mary (Scott Simon)
John Henry Faulk's Christmas Story (John Henry Faulk)
All Songs Considered for the Holidays
9:00 PM on 90.3 WCPN
It's the sixth edition of a weird holiday tradition from NPR Music. Host Bob Boilen and friends trade holiday cheer and snarky barbs while bringing you the best holiday songs from new and emerging breakout bands. Hear renditions of great holiday music you'll never hear at the mall or your mother's house.
A Festival of Nine Lessons and Carols
10:00 AM on 90.3 WCPN
Hosted by Michael Barone, this is a live stereo music and spoken-word broadcast from the chapel of King's College in Cambridge, England. The 30-voice King's College Choir performs the legendary Festival of Nine Lessons and Carols service of Biblical readings and music.
As It Happens annual reading of The Sheppard
8:00 PM on 90.3 WCPN
The Shepherd is a 1976 novel by Frederick Forsyth; created originally as a Christmas gift to his wife after she requested a ghost story be written for her. Written on Christmas Day, and published near that time a year later, the idea came while trying to think of a setting away from the typical haunted homes, and seeing planes flying overhead. Forsyth, a former RAF pilot, relates the story of a De Havilland Vampire pilot going home on Christmas Eve 1957, whose aircraft suffers a complete electrical failure en route from northern Germany to Suffolk. Lost in fog and low on fuel, he is met and led (or shepherded) to a disused RAF dispersal field by the pilot of a De Havilland Mosquito fighter/bomber of WWII vintage, who has apparently been sent up to guide him in. His attempts to find a rational explanation for his eventual rescue prove troublesome. However, some time after he lands at the airfield he learns that his savior was Johnny Kavanagh, a wartime RAF pilot who had been stationed there and who had guided crippled bombers home. The Vampire pilot also learns that Kavanagh disappeared over the North Sea in his Mosquito on his last mission, on Christmas Eve, exactly fourteen years before. Beginning in 1979 the story has been broadcast each year on Christmas Eve on the CBC As It Happens, read by the late Alan Maitland.
The Cleveland Orchestra Messiah
9:00 PM on 90.3 WCPN
The Cleveland Orchestra performs Handel's Messiah at Severance Hall
A Festival of Nine Lessons and Carols re-air
11:00 PM on 90.3 WCPN
Hosted by Michael Barone, this is a live stereo music and spoken-word broadcast from the chapel of King's College in Cambridge, England. The 30-voice King's College Choir performs the legendary Festival of Nine Lessons and Carols service of Biblical readings and music.
A Jazz Zone Christmas
1:00 AM on 90.3 WCPN
Hosted by Billy and Renee Foster, this is a two hour program of music by top jazz musicians, Wynton Marsalis, Vincent Herring, Nnenna Freelon, Carmen Lundy, Charlie Parker, Tim Warfield and many more, playing their exciting arrangements of your favorite Christmas classics. This entertaining program includes quips, quotes and enlightening holiday wishes from your hosts. This is the third in a series by the Billy Foster Jazz Zone.
Jazz Sounds of Christmas
3:00 AM on 90.3 WCPN
The perfect holiday stocking stuffer. Hosted by Billy and Renee Foster, this is a two hour program of music by top jazz musicians, Wynton Marsalis, Vincent Herring, Nnenna Freelon, Carmen Lundy, Charlie Parker, Tim Warfield and many more, playing their exciting arrangements of your favorite Christmas classics. This entertaining program includes quips, quotes and enlightening holiday wishes from your hosts. This is the third in a series by the Billy Foster Jazz Zone.
Jonathan Winters' A Christmas Carol
9:00 AM on 90.3 WCPN
An updated version of a public radio tradition hosted by NPR's Susan Stamberg. Master comedian Jonathan Winters presents a distinctive reading of Dickens' holiday classic, with a special performing edition prepared by Dickens for his own presentations. Also featuring Mimi Kennedy. From NPR and KCRW.
An Afro Blue Christmas
10:00 AM on 90.3 WCPN
Join us for a very special holiday concert with Howard University's premiere vocal ensemble Afro Blue, and special guest pianist Cyrus Chestnut. The acappela group performs a variety of holiday songs including African-American spirituals, jazz and pop tunes, and classical repertoire. The joyous celebration includes one of a kind arrangements on traditional holiday songs plus new compositions… music perfect for the holidays and the spirit of Christmas. Hosted by Michele Norris.
Jazz Piano Christmas XXX
11:00 AM on 90.3 WCPN
NPR Music brings you another great concert from the John F. Kennedy Center for the Performing Arts. Pianists Cyrus Chestnut, Kris Davis, Lynne Arriale and The "Master" Harold Mabern take the stage to perform their favorite holiday songs. Hosted by Felix Contreras.
Festivo Alt.Latino with Coral Cantigas
2:00 PM on 90.3 WCPN
NPR Music's Alt.Latino presents the 3rd edition of Festivo Alt.Latino—a special holiday concert featuring the 20 piece choral ensemble Choral Cantigas. This musical performance also includes stories about holiday traditions and cultures. Hear a traditional Peruvian Christmas carol, folk music from Brazil, Spain, and Mexico plus Parrandas from Venezuela and Puerto Rico. The many rich styles of Latino choral music will unite listeners through the joyful and transformative power of music. Hosted by Felix Contreras.
Tinsel Tales 3: NPR Christmas Favorites
10:00 PM on 90.3 WCPN
Listeners tune to NPR for holiday stories of all kinds; funny, touching, insightful, and surprising. Hear the latest version of evergreen delights while driving to the mall, entertaining friends, or relaxing in front of a crackling fire. Hosted by Lynn Neary. Story details coming soon!
A Seasons Griot
9:00 PM on 90.3 WCPN
"A Season's Griot" is public radio's only nationally syndicated Kwanzaa program. Hosted by acclaimed storyteller Madafo Lloyd Wilson, this annual one-hour special captures the tales and traditions of African-American and African peoples.
This one-hour celebration in story and song is public radio's only nationally syndicated Kwanzaa program. Hosted for nearly 20 years by acclaimed storyteller Madafo Lloyd Wilson, this annual special captures the tales and traditions of African American and African peoples. This year's program will celebrate Family with familiar and favorite elements of Griot, and plenty of music.
Toast of the Nation 2014
9:00 PM on 90.3 WCPN
Toast of the Nation 2014-2015 will make New Year's Eve stops all around the country.
An NPR tradition every New Year's Eve, Toast of the Nation is perfect for the occasion. It's jazz that you can party to, all night from coast to coast, with countdowns to midnight in all four continental time zones. Spirited, improvised, grooving and swinging, each segment is a stop in a sequence of celebrations and contributing something new to the musical feast.
Capitol Steps: Politics Takes a Holiday New Year's Edition 2014
9:00 AM on 90.3 WCPN
Help say good-bye and good riddance to 2014 with the Capitol Steps and their annual year-end review. It's all in their hour-long special of "Politics Takes a Holiday!"
New Year's Day from Vienna 2015
11:00 AM on 90.3 WCPN
The Philharmonic presents its ever popular annual New Year's Day concert from the Golden Hall of the Musikverein in Vienna. You'll hear your favorite waltzes, polkas and more—a festive way to start off the New Year. Presented by NPR Music and WGBH, Boston.
Capitol Steps: Politics Takes a Holiday New Year's Edition 2014
7:00 PM on 90.3 WCPN
Help say good-bye and good riddance to 2014 with the Capitol Steps and their annual year-end review. It's all in their hour-long special of "Politics Takes a Holiday!"


text: Repositório Colecção: http://hdl.handle.net/10400.18/50 2014-11-28T00:17:55Z Advantages and Versatility of Fluorescence-Based Methodology to Characterize the Functionality of LDLR and Class Mutation Assignment http://hdl.handle.net/10400.18/2467 Título: Advantages and Versatility of Fluorescence-Based Methodology to Characterize the Functionality of LDLR and Class Mutation Assignment Autor: Etxebarria, A.; Benito-Vicente, A.; Alves, A.C.; Ostolaza, H.; Bourbon, M.; Martin, C. Resumo: Familial hypercholesterolemia (FH) is a common autosomal codominant disease with a frequency of 1∶500 individuals in its heterozygous form. The genetic basis of FH is most commonly mutations within the LDLR gene. Assessing the pathogenicity of LDLR variants is particularly important to give a patient a definitive diagnosis of FH. Current studies of LDLR activity ex vivo are based on the analysis of 125I-labeled lipoproteins (reference method) or fluorescent-labelled LDL. The main purpose of this study was to compare the effectiveness of these two methods to assess LDLR functionality in order to validate a functional assay to analyse LDLR mutations. LDLR activity of different variants has been studied by flow cytometry using FITC-labelled LDL and compared with studies performed previously with 125I-labeled lipoproteins. Flow cytometry results are in full agreement with the data obtained by the 125I methodology. Additionally confocal microscopy allowed the assignment of different class mutation to the variants assayed. Use of fluorescence yielded similar results than 125I-labeled lipoproteins concerning LDLR activity determination, and also allows class mutation classification. The use of FITC-labelled LDL is easier in handling and disposal, cheaper than radioactivity and can be routinely performed by any group doing LDLR functional validations. 2014-11-11T00:00:00Z Protein Interaction Networks Reveal Novel Autism Risk Genes within GWAS Statistical Noise http://hdl.handle.net/10400.18/2466 Título: Protein Interaction Networks Reveal Novel Autism Risk Genes within GWAS Statistical Noise Autor: Correia, C.; Oliveira, G.; Vicente, A.M. Resumo: Genome-wide association studies (GWAS) for Autism Spectrum Disorder (ASD) thus far met limited success in the identification of common risk variants, consistent with the notion that variants with small individual effects cannot be detected individually in single SNP analysis. To further capture disease risk gene information from ASD association studies, we applied a network-based strategy to the Autism Genome Project (AGP) and the Autism Genetics Resource Exchange GWAS datasets, combining family-based association data with Human Protein-Protein interaction (PPI) data. Our analysis showed that autism-associated proteins at higher than conventional levels of significance (P<0.1) directly interact more than random expectation and are involved in a limited number of interconnected biological processes, indicating that they are functionally related. The functionally coherent networks generated by this approach contain ASD-relevant disease biology, as demonstrated by an improved positive predictive value and sensitivity in retrieving known ASD candidate genes relative to the top associated genes from either GWAS, as well as a higher gene overlap between the two ASD datasets. Analysis of the intersection between the networks obtained from the two ASD GWAS and six unrelated disease datasets identified fourteen genes exclusively present in the ASD networks. These are mostly novel genes involved in abnormal nervous system phenotypes in animal models, and in fundamental biological processes previously implicated in ASD, such as axon guidance, cell adhesion or cytoskeleton organization. Overall, our results highlighted novel susceptibility genes previously hidden within GWAS statistical "noise" that warrant further analysis for causal variants. 2014-11-19T00:00:00Z The Autism Simplex Collection: an international, expertly phenotyped autism sample for genetic and phenotypic analyses http://hdl.handle.net/10400.18/2465 Título: The Autism Simplex Collection: an international, expertly phenotyped autism sample for genetic and phenotypic analyses Autor: Buxbaum, J.D.; Bolshakova, N.; Brownfeld, J.M.; Anney, R.J.; Bender, P.; Bernier, R.; Cook, E.H.; Coon, H.; Cuccaro, M.; Freitag, C.M.; Hallmayer, J.; Geschwind, D; Klauck, S.M.; Nurnberger, J.I.; Oliveira, G.; Pinto, D.; Poustka, F.; Scherer, W.S.; Shih, A.; Sutcliffe, J.S.; Szatmari, P.; Vicente, A.M.; Vieland, V.; Gallagher, L. Resumo: BACKGROUND: There is an urgent need for expanding and enhancing autism spectrum disorder (ASD) samples, in order to better understand causes of ASD. METHODS: In a unique public-private partnership, 13 sites with extensive experience in both the assessment and diagnosis of ASD embarked on an ambitious, 2-year program to collect samples for genetic and phenotypic research and begin analyses on these samples. The program was called The Autism Simplex Collection (TASC). TASC sample collection began in 2008 and was completed in 2010, and included nine sites from North America and four sites from Western Europe, as well as a centralized Data Coordinating Center. RESULTS: Over 1,700 trios are part of this collection, with DNA from transformed cells now available through the National Institute of Mental Health (NIMH). Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule-Generic (ADOS-G) measures are available for all probands, as are standardized IQ measures, Vineland Adaptive Behavioral Scales (VABS), the Social Responsiveness Scale (SRS), Peabody Picture Vocabulary Test (PPVT), and physical measures (height, weight, and head circumference). At almost every site, additional phenotypic measures were collected, including the Broad Autism Phenotype Questionnaire (BAPQ) and Repetitive Behavior Scale-Revised (RBS-R), as well as the non-word repetition scale, Communication Checklist (Children's or Adult), and Aberrant Behavior Checklist (ABC). Moreover, for nearly 1,000 trios, the Autism Genome Project Consortium (AGP) has carried out Illumina 1 M SNP genotyping and called copy number variation (CNV) in the samples, with data being made available through the National Institutes of Health (NIH). Whole exome sequencing (WES) has been carried out in over 500 probands, together with ancestry matched controls, and this data is also available through the NIH. Additional WES is being carried out by the Autism Sequencing Consortium (ASC), where the focus is on sequencing complete trios. ASC sequencing for the first 1,000 samples (all from whole-blood DNA) is complete and data will be released in 2014. Data is being made available through NIH databases (database of Genotypes and Phenotypes (dbGaP) and National Database for Autism Research (NDAR)) with DNA released in Dist 11.0. Primary funding for the collection, genotyping, sequencing and distribution of TASC samples was provided by Autism Speaks and the NIH, including the National Institute of Mental Health (NIMH) and the National Human Genetics Research Institute (NHGRI). CONCLUSIONS: TASC represents an important sample set that leverages expert sites. Similar approaches, leveraging expert sites and ongoing studies, represent an important path towards further enhancing available ASD samples. 2014-05-20T00:00:00Z Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data http://hdl.handle.net/10400.18/2464 Título: Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data Autor: Holmes, M.V.; Dale, C.E.; Zuccolo, L.; et al.; InterAct Consortium Resumo: To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease. DESIGN: Mendelian randomisation meta-analysis of 56 epidemiological studies. Descrição: Lista completa dos Autores: Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, Leusink M, Sundstrom J, Hubacek JA, Pikhart H, Swerdlow DI, Panayiotou AG, Borinskaya SA, Finan C, Shah S, Kuchenbaecker KB, Shah T, Engmann J, Folkersen L, Eriksson P, Ricceri F, Melander O, Sacerdote C, Gamble DM, Rayaprolu S, Ross OA, McLachlan S, Vikhireva O, Sluijs I, Scott RA, Adamkova V, Flicker L, Bockxmeer FM, Power C, Marques-Vidal P, Meade T, Marmot MG, Ferro JM, Paulos-Pinheiro S, Humphries SE, Talmud PJ, Mateo Leach I, Verweij N, Linneberg A, Skaaby T, Doevendans PA, Cramer MJ, van der Harst P, Klungel OH, Dowling NF, Dominiczak AF, Kumari M, Nicolaides AN, Weikert C, Boeing H, Ebrahim S, Gaunt TR, Price JF, Lannfelt L, Peasey A, Kubinova R, Pajak A, Malyutina S, Voevoda MI, Tamosiunas A, Maitland-van der Zee AH, Norman PE, Hankey GJ, Bergmann MM, Hofman A, Franco OH, Cooper J, Palmen J, Spiering W, de Jong PA, Kuh D, Hardy R, Uitterlinden AG, Ikram MA, Ford I, Hyppönen E, Almeida OP, Wareham NJ, Khaw KT, Hamsten A, Husemoen LL, Tjønneland A, Tolstrup JS, Rimm E, Beulens JW, Verschuren WM, Onland-Moret NC, Hofker MH, Wannamethee SG, Whincup PH, Morris R, Vicente AM, Watkins H, Farrall M, Jukema JW, Meschia J, Cupples LA, Sharp SJ, Fornage M, Kooperberg C, LaCroix AZ, Dai JY, Lanktree MB, Siscovick DS, Jorgenson E, Spring B, Coresh J, Li YR, Buxbaum SG, Schreiner PJ, Ellison RC, Tsai MY, Patel SR, Redline S, Johnson AD, Hoogeveen RC, Hakonarson H, Rotter JI, Boerwinkle E, de Bakker PI, Kivimaki M, Asselbergs FW, Sattar N, Lawlor DA, Whittaker J, Davey Smith G, Mukamal K, Psaty BM, Wilson JG, Lange LA, Hamidovic A, Hingorani AD, Nordestgaard BG, Bobak M, Leon DA, Langenberg C, Palmer TM, Reiner AP, Keating BJ, Dudbridge F, Casas JP; InterAct Consortium. 2014-07-01T00:00:00Z


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Selena's Scandalous Selfie Sparks Drama
Emma Watson's Intentional "Side Boob"
10 Pairs Of Stars Often Confused For Each Other
The Embarrassing Reason Khloe Kardashian Knew She Needed to Lose Weigh
16 Celebrities With Royal Blood
15 Unquestionably Creepy Celebrities
Taylor Swift is Taking Over Victoria's Secret
Home / Photos Beyonce: Her Face Says It All
What the Devil? Drake Flashes Rihanna's Picture Along With Satan?
Watch Miley Cyrus Fall Down on Stage Wearing a Fake Butt
Kim K and The Jenners Act Totally Shameless
20 Super Awkward Celebrities
Kim Kardashian Talks Waist Training and Kylie's Lips
Nick Jonas Explains Hilarious Photoshopped Kim Kardashian Butt Pic
Inside Kim and Kanye's $20 Million Mega Mansion
30 Child Stars Who Died Young
Can You Guess Which One of These Celebs is Older?
45 Of Your Childhood Crushes (Then And Now)
Kim Kardashian Sparks a Cosmetic Surgery Trend
The Most Educated Rappers in The Game
Kylie Jenner Addresses the Lip Injection Rumors Again
Diddy Hosts Brunch for All of His Baby Mamas
Celebrities Who Have Aged the Worst
Kylie Jenners $1 Million Plastic Surgery Shocker
A New Site Exposes Everyone's Past. What Can You Uncover?
14 Celebrity Moms Who Breastfeed in Public
6 Embarrassing and Unforgettable Celeb Moments
Demi Lovato Shares Her Love for Curvy Women
Taylor Swift Just Broke Her Own Fashion Record


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Porch pillars. Window and door trim. Idea of no railing for back covered porch/deck.
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Adirondack chairs. — Nick
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Classic Family Home
conversion or vice versa? Either way, such a unique and well executed idea!
conservatory idea...Classic Family Home
Outdoor but warm — 8vhearts
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Shingle style home in Hanover NH
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Idea for rock at entry and around the deck
breezeway pillar ideas (even house)
Covered Walkway — anniemq
Yvonne McFadden LLC
Market and Dining Room
5 or 6 years ago. Aidan Gray has something very similar as well as Gabby Home. They may only sell to the trade, if you would like to purchase please let
Lani idea...arch idea
arches — Liana Gonzalez
Mediterranean Landscape
Are there more pictures of this home? It is just lovely. Thank you
fountains, ideas for private outdoor space/patio
Court yard ideas
Piso, fuente y macetas — elenacorvera
KohlMark Architects and Builders
choice for a sunroom with many windows. Tell us: Do you have a hopper in your home?
idea for outside of bedroom
Large size and pattern of natural cleft slate floor — shutte
Milieu Design
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Idea for new percola !...Fence idea
Clematis, beautiful gate — barbaragugs


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Morocco: 32 dead from floods in southern Morocco
Afghanistan: Bomb blasts, gun battles kill 11, wound 13
Paksitan: Suspected Ebola virus patient dies in Faisalabad
Israel: Netanyahu's push for Jewish nationality law risks Israeli coalition
US: Looters set fire to buildings after grand jury decision
Palestine: Israelis prevent 100 tons of vegetables from exporting out of Gaza
Libyan pro-Govt fighters wrest control of key town from rebels
Austria: Iran, West extend nuclear talks to June after failing to meet deadline
Afghanistan: 45 killed, 60 injured in eastern Afghan suicide attack
US police fatally shoot 12-year-old boy holding fake gun
Palestine: Israeli soldiers kidnap Palestinian woman in Jerusalem
Palestine: Israel army shoots dead Palestinian in Gaza
Palestine: Palestinian killed by Israeli explosive in West Bank
Palestine: Several Palestinians injured in Israeli attacks across West Bank
Palestine: Palestinian teen seriously injured, 2 taken at Gaza border
Palestine: Israeli military beat & detain young men in Hebron
Bahrain opposition slams 'ridiculous' official voter turnout rate
Iran 'prepared' to extend nuclear talks
Palestine: Palestinians targeted with live fire amid state of hate attacks
Palestine: Israeli 'home demolitions, collective punishment, are a war crime' says rights group
Prime Minister, David Cameron, joined over 800 people to celebrate the very best of Muslim contribution to British society. The Twelfth The Muslim News Awards for Excellence gala dinner, Britain's longest standing Muslim awards event, was held in central London.
Egypt must rank high as an insidious example of British foreign policy. If there are any cynics unsure what the British Government's position is towards Egypt's military rulers, it officially remains the same: committed to working with the international community "to providing support during the transition process and beyond."
Prime Minister, David Cameron, is adamant that he wishes to challenge intolerant views about Muslims but which will require a sea change in cultural attitudes that has institutionalised extremism with Islam.
Sajid Javid spoke of his immense privilege at succeeding Maria Miller as Culture Secretary, becoming the first Muslim Secretary of State.
A special needs teacher has been hailed a hero after donating one of his kidneys to save the life of a seriously ill student.
Muslim primary schools have again exceeded the national average pass rate in the Key Stage 2 Level 4 and above exams, a level expected for 11-year-olds in their last year in primary school.
Britain's first Voluntary Aided Muslim primary school has achieved an outstanding Ofsted report, the highest rating from the education inspectorate body.
Faith schools have been banned from censoring exam questions that contradict their religious beliefs, the qualifications watchdog has ruled.
A 21-year-old Leicester man has admitted importing and possessing a haul of prohibited weapons.
Shadow Secretary for Justice, Sadiq Khan MP, has earned yearlong gloating rights over his Shadow Cabinet colleagues after completing the London Marathon in 4 hours 19 minutes, well ahead Shadow Chancellor Ed Balls (4: 57:40) and Shadow Secretary of State for Health Andy Burnham (4:26:19).
One of the hallmarks of the Coalition Government has been its austerity rhetoric. Since May 2010, we have been told incessantly that the Labour Government left a huge deficit and that we must tighten our belts to reduce it.
Prime Minister, David Cameron's decision to launch an investigation into the Muslim Brotherhood, has been branded a "political stunt" designed to bolster Britain's trade relations with Saudi Arabia and the UAE but will more than likely backfire.
UN Secretary General, Ban Ki-moon, voiced his "strong concerns" over the mass death sentences delivered to 529 supporters of Egypt's ousted President Mohamed Morsi.
UN Secretary General, Ban Ki-moon's short visit to Central African Republic (CAR) earlier this month, warned the country would become another Rwanda if nothing is done.
FIFA has given Israel until the summer to improve travel and playing conditions for Palestinian soccer players, with the threat of expulsion as a member of soccer's world governing body hanging ominously overhead.
Calls for the Al-Jazeera journalists imprisoned in Egypt to be released by press freedom advocates have intensified after three of the four foreign journalists detained passed the 100 days in prison mark.
An Iranian mother has received world-wide praise for her "powerful act of forgiveness" after she spared her son's killer during what was supposed to have been his public execution.
Muslim prayer room signs have been vandalised at King's College London Guy's campus, with one sign having "Muslim" scratched out and other with a "#jewish" sticker over the same word.
New York Police Department (NYPD) confirmed that it has disbanded its controversial surveillance unit that tracks the daily lives of Muslims to detect terror threats.
A couple from Middlesbrough say bosses at supermarket giant Morrisons religiously discriminated against them when they were refused time off during Ramadan.
Leader of France's far-right Front National (FN), Marine Le Pen has vowed to stop non-pork meal options in school canteens in towns where her party won local elections.
A Hijab wearing Swedish woman claims security staff Arvidsjaur northern airport tugged on her hijab in public rather than take up her offer to remove it in private.
A 15-year-old Muslim girl was spat and threatened with violence and called a "terrorist" by a middle aged man on her way to school while fellow bus passengers laughed at her ordeal.
Court of Appeal recently considered two cases on the issue of vicarious liability of employers. This refers to a situation where an employer is held responsible for the acts or omissions of another person, and arises where two conditions are met.
The book under review is an interesting study of the Kashmiri people's popular resistance against Indian hegemony through the life and struggle of Syed Ali Shah Geelani.
The memoir is, in many ways, the story of her happy partnership with her husband as well as her progression in politics.
When it comes to scientific discussions about climate change, there always seems to be controversy over how the data is interpreted.
Scientists have made the first artificial chromosome (packages of DNA that contain the genes), which promises to revolutionise medical and industrial biotechnology in the coming century.