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1-20 of 250 items from 2014 « Prev | Next »
15 hours ago | EW.com - PopWatch | See recent EW.com - PopWatch news »
Peter and Bobby Farrelly defined a new kind of big screen comedy in the '90s. Dumb and Dumber, There's Something About Mary, Kingpin: The utterly unique Farrelly blend of lighthearted goofery and gross-out shenanigans created some of the great kitchen-sink comedies of the era. A few days before the siblings released their hit sequel Dumb and Dumber To, the Farrelly Brothers talked about their career and their process. It's all part of Lightbulb, EW's new series that features today's leading creators talking about their work and their inspiration. »
- Darren Franich
25 November 2014 4:56 AM, PST | Digital Spy | See recent Digital Spy - Movie News news »
Not even two dodgy sequels and 21 years passing can erase the magic of the very first time you watched Jurassic Park.
The Steven Spielberg dino adventure brought gasps from audiences - young and old - when it premiered around the world in 1993. Even today, a couple of seconds of that classic score can give you tingles and take you back to first time you saw The Park.
Like all great films, everything felt and looked like it slotted together perfectly. But that wasn't necessarily the case, as there were plenty of other big-name stars who so very nearly got the lead roles.
1. Harrison Ford was nearly... Dr Alan Grant
If it wasn't already greedy enough that Harrison Ford had landed himself awesome cool roles in two of the biggest movie franchises of all time - Star Wars and Indiana Jones - he could have almost have added a third dino-sized »
24 November 2014 10:37 AM, PST | CinemaNerdz | See recent CinemaNerdz news »
While it may be strange to think that The Hunger Games: Mockingjay – Part 1 failed to live up to the financial openings of the previous two films, it did not stop it from being the biggest box office opening weekend of 2014. At an estimated $123 million, it trounced the big four Marvel entries of the year, the reboot of Godzilla, and even Transformers: Age of Extinction, though it has yet to release budget numbers for reasons unknown. With numbers like that, it is well on its way to being the highest grosser of the year, if its numbers hold (even if it is getting slightly less critical praise than the previous entries).
Comparatively, the rest of the competition could barely tread water, despite not doing all that poorly compared to the previous week. Big Hero 6 (estimated $20.1 million) came back against Dumb and Dumber To (which fell to fourth with an »
- Seth Paul
23 November 2014 12:26 PM, PST | Deadline New York | See recent Deadline New York news »
Peter Bart and Mike Fleming Jr. worked together for two decades at Daily Variety. In this occasional column, two old friends get together and grind their axes, mostly on the movie business.
Bart: Critics don't like to admit it, but the conditions under which you see a film strongly influence your opinion. Birdman is a good example: If you see a film like this with a pack of cinephiles like at Telluride, everyone gets every inside joke, and you instinctively go along with the crowd. I made it a point to see Birdman with a paid civilian audience and it was like screening it in a mausoleum. No laughs, just occasional grunts and lots of walkouts. Some reviews predicted Birdman "will captivate arthouse and multiplex crowds alike and send awards pundits into orbit" (the Variety review). Well that ain't happening with the audiences; we'll see about the awards. »
- Mike Fleming Jr
21 November 2014 11:00 AM, PST | EW.com - PopWatch | See recent EW.com - PopWatch news »
Every week in Sound Bites, EW spotlights the most memorable lines of the week. This week features Jimmy Fallon's crack on Kim Kardashian's (butt) crack, Nick (Jake Johnson) addressing the laziness of men in New Girl, and a burn on Arizona State from Dumb and Dumber To. These are the best quotes of this week gathered from TV, film, and more. »
- Teresa Jue
20 November 2014 7:08 PM, PST | Movies.com | See recent Movies.com news »
As of today, Dumb and Dumber To - a sequel to an absurd, 20-year-old comedy - has been in theaters for less than a week and is already sitting on a box office haul of over $55 million. So when a simple, long-overdue sequel hits big, you can bet that Hollywood is paying attention, and that typically means trying to do something similar. Enter Zoolander 2. The first Zoolander isn't quite as old as Dumb and Dumber, nor did it ever gain the same kind of household recognition, but it's had a very healthy life on DVD, cable and Netflix since it came out in 2001. The comedy, about dumb male models thwarting a plot to kill a politician, has more than a few fans and Ben Stiller is hoping they'll turn out for a sequel. He's not directing this time around (that job goes to...
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- Peter Hall
20 November 2014 1:14 PM, PST | Fandango | See recent Fandango news »
As of today, Dumb and Dumber To -- a sequel to an absurd, 20-year-old comedy -- has been in theaters for less than a week and is already sitting on a box office haul of over $55 million. So when a simple, long-overdue sequel hits big, you can bet that Hollywood is paying attention. Enter Zoolander 2. The first Zoolander isn't quite as old as Dumb and Dumber, nor did it ever gain the same kind of household recognition, but it's had a very healthy life on DVD, cable and Netflix since...
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- email@example.com
20 November 2014 11:49 AM, PST | ShockYa | See recent ShockYa news »
Title: Dumb and Dumber To Director: Bobby Farrelly & Peter Farrelly Starring: Jim Carrey, Jeff Daniels, Kathless Turner, Rob Riggle, Laurie Holden, Rachel Melvin, Steve Tom, Don Lake, Patricia French. Dumb and Dumber Two or Dumb and Dumber Too? Either way the intentional typo reiterates the stupidity of our protagonists who are back after two decades. Jim Carrey and Jeff Daniels have aged badly but more than their farcical out of date "dumb play," the true problem of 'Dumb and Dumber To' lies in the script, drenched with language and coarsely vulgar gags. Twenty years since Dumb and Dumber's first adventure, Harry finds out he has a daughter who was [ Read More ]
The post Dumb and Dumber To Movie Review appeared first on Shockya.com. »
- Chiara Spagnoli Gabardi
19 November 2014 12:38 PM, PST | Flickeringmyth | See recent Flickeringmyth news »
Scott Davis chats with Dumb and Dumber To star Brady Bluhm…
Twenty years after the original grossed over $240 million, Jim Carrey, Jeff Daniels and The Farrelly Brothers are back with a bang. Dumb and Dumber To was released to huge box office takings this last weekend, landing straight into the No.1 spot in the States with a huge $36million bow. But Carrey and Daniels aren't the only people reprising their roles from the original, as actor Brady Bluhm returns to the Dumb-verse as Billy in 4C, the "blind kid" who Lloyd so famously sold Harry's dead parakeet to in the original.
In an exclusive interview with Flickering Myth, Staff Writer Scott J. Davis was able to talk with Brady about all things Dumb, and what it was like to be back two decades later….
Scott Davis: What have you been up to in the two decades since Dumb and Dumber? »
- Scott J. Davis
19 November 2014 10:44 AM, PST | Variety - Film News | See recent Variety - Film News news »
In this week's edition of the Variety Movie Commercial Tracker, powered by iSpot.tv, "Horrible Bosses 2″ again claimed the top spot in TV ad spend, fending off challenges by the upcoming "The Hunger Games: Mockingjay Part One" and "Exodus: Gods and Kings."
"Bosses" posted an estimated outlay of $7.1 million for the week across 852 spots airing on 43 networks, led by MTV and Comedy Central. That's $4.1 million less that last week's estimated spend, but was still enough to hold off the run-up to "Mockingjay," outspending it by just $600,000. "Mockingjay," which premiers Nov. 21, claimed the second-place spot, spending an estimated $6.7 million spread between 797 spots on 37 networks, let by TV Guide Network and MTV.
"Exodus: Gods and Kings" made its debut in the top five with a $4.2 million spend across 413 spots on 38 networks, while "Penguins of Madagascar" remained in the top 5 spenders at No. 4. Despite being the only new »
- iSpot.tv
19 November 2014 9:25 AM, PST | Variety - Film News | See recent Variety - Film News news »
With audiences growing tired of "Spider-Man" or "Transformers" sequels, Hollywood now has a solution — go back to the '90s.
"Dumb and Dumber To," which opened to atrocious reviews 20 years after the original, still scored an impressive $36 million at the box office last weekend. (Read all the reasons why it worked from my colleague Brent Lang.) It shouldn't have come as a surprise: the '90s are hot again. This week, Twitter went nuts over a "Dawson's Creek" reunion photo of James Van Der Beek and Joshua Jackson, while Focus Features announced "Can't Touch This" (borrowing from the Mc Hammer song), a '90s-set high school dance-a-thon directed by Jon M. Chu. If Robin Williams had lived to star in "Mrs. Doubtfire 2," it would no doubt have been a hit too.
As executives inevitably start to dig through the recycling bin of old titles that never got a second chapter, »
- Ramin Setoodeh
19 November 2014 5:40 AM, PST | MUBI | See recent MUBI news »
Above: a sultry new poster for Paul Thomas Anderson's Inherent Vice. Dumb and Dumber To has opened to unsurprisingly mixed reviews, but Farrelly brothers champion R. Emmet Sweeney makes a case for the long awaited sequel for Film Comment:
"Dumb and Dumber To is about a deep, abiding friendship that can survive any indignities. After Harry and Lloyd's journey is over, they've tossed away fortunes and frittered away kidneys, but they need each other to survive. As each momentary acquaintance slinks, or runs, away, it's up to Harry and Lloyd to forget and move on. Or as is the case for Lloyd, to think about ninjas and wake up licking the grill of a big rig. Either way they can't live without each other. And though they could never admit it, or even form the words in their desiccated cortexes, what they have is something like love. »
- Notebook
18 November 2014 4:47 PM, PST | The Hollywood Reporter | See recent The Hollywood Reporter news »
A version of this story first appeared in the Nov. 28 issue of The Hollywood Reporter magazine. New Line Cinema executives must have squirmed as the Farrelly brothers' Dumb and Dumber To scored a $36.1 million domestic debut, far better than predicted for a sequel opening two decades after the original. In early 2013, New Line chief Toby Emmerich let rights to the sequel go when higher-ups at parent Warner Bros. didn't want to release it, even after Red Granite Pictures — backer of The Wolf of Wall Street — said it would help finance the film for less than $40
read more
- Pamela McClintock
18 November 2014 7:48 AM, PST | Filmonic.com | See recent Filmonic news »
Almost 20 years after the original, Dumb and Dumber To still had what it takes to top the domestic box office, ahead of strong holdovers Big Hero 6 and Interstellar. Ok so maybe "barely outsmarts Big Hero 6″ would be a better title as the animation was just $1.5 million shy of Dumb and Dumber […]
Read Box Office: Dumb and Dumber To Outsmarts Big Hero 6 on Filmonic.
- Alex
18 November 2014 7:45 AM, PST | The Hollywood Reporter | See recent The Hollywood Reporter news »
Jim Carrey stopped by The Tonight Show Starring Jimmy Fallon on Monday to promote Dumb and Dumber To, and he brought along a friend — the dummy version of Jeff Daniels. Carrey pointed out that he wasn't the best ventriloquist, and that the audience could likely see his lips moving. But his puppet friend Daniels had a great solution to help him out with his issue. What a nice friend. The pair then broke out into song. Is this the makings of a Dumb and Dumber trilogy? Read more 10 Best 'Dumb and Dumber' Callbacks in the Sequel
read more
- Lorena O'Neil
17 November 2014 11:52 AM, PST | cinemablend.com | See recent Cinema Blend news »
Dumb and Dumber To is a hit. A large hit. Not quite a massive hit, but significant enough that it has ramped up chatter for a third Dumber to find its way into pre-production. After all, the Dumb and Dumber sequel now stands as the highest-grossing opening weekend on the Farrelly Brothers. resume. And it gave Jim Carrey his highest live-action opening since Bruce Almighty, back in 2003. Eric wrote about the amusing tease for a follow-up Dumb and Dumber movie that was shared during the end credits of this current sequel. But now that fans have shown they support Jim Carrey going back and revisiting some of his classic characters, I make a pitch for a new movie featuring This rubber-faced genius. Can we make it happen, Mr. Carrey? Want to read more about Dumb and Dumber To. We have a lot of coverage on: - The Jennifer Lawrence cameo »
17 November 2014 8:00 AM, PST | FilmSchoolRejects.com | See recent FilmSchoolRejects news »
The bowl cut is (as best summarized by Gary Larson), nature's way of saying "do not touch." This is the haircut of a child (worse, a child with zero fashion sense). If worn by a child, don't touch, because hey- that's not your child. On an adult, don't touch, because whomever sports the bowl cut may not be of sound mind or body. Or they could be Jim Carrey, filming a Dumb and Dumber sequel. Lloyd Christmas has returned, and with him, the rattling rattlesnake tail of the haircut world. But Lloyd isn't the only one to take his fashion cues from a salad bowl- he's one of many in a long line of bowl-cutted heroes, American patriots who've upheld a ruler-straight hairline for nearly a century. Let's take a look at a few, shall we? Moe Howard, The Three Stooges The Great Depression was a dour period in »
- Adam Bellotto
17 November 2014 6:24 AM, PST | JoBlo.com | See recent JoBlo news »
Sequel talk isn't uncommon, even before a movie comes out, but it seems as though the Farrellys had a good time hamming it up with Jim Carrey and Jeff Daniels as they seem pretty keen on returning to the world of Dumb and Dumber. Despite reviews not being so hot on this sequel taking place 20 years later (you can check out our review here), the flick managed to rake in $38 million this weekend! Word is that's pretty much all the film's budget right there, so the idea »
- Sean Wist
17 November 2014 6:00 AM, PST | FilmSchoolRejects.com | See recent FilmSchoolRejects news »
There is a Dumb and Dumber cartoon. It is insane and it demands your attention. This may come as a shock if you weren't watching animation on ABC in the mid-1990s. It was never exactly well-regarded, or even regarded at all. It was canceled after its first season, which ran from October of 1995 through February of 1996. Harry and Lloyd only managed to gallivant through 13 episodes before they were evicted from the screen until 2003's ill-begotten prequel and, of course, Dumb and Dumber To. The characters, created by the Farrelly Brothers, have had quite a bizarre franchise history. That said, the Farrelly Brothers were not directly involved with Dumb and Dumber the TV series. It was their co-writer on the original film, Bennett Yellin, who stepped in to write the television series. It was produced by Hanna-Barbera, their last project for ABC. This was an important moment for the storied animation studio, which »
- Daniel Walber
17 November 2014 5:15 AM, PST | Moviefone | See recent Moviefone news »
Poor Lloyd and Harry. The perpetual underachievers of the "Dumb and Dumber" movies have been underestimated by everyone.
Certainly, few pundits expected much from "Dumb and Dumber To," the poorly reviewed sequel to a 20-year-old movie, starring a Jim Carrey whose box office strength has dwindled over the last decade. Besides, last week's champ, "Big Hero 6," seemed unstoppable and poised for a repeat victory, with about $35 million in likely earnings. "Dumber," by contrast, wasn't expected to top $29 million.
Nonetheless, "Dumber" confounded the sages and came out on top, with an estimated $38.1 million. How did it defy conventional wisdom for a come-from-behind victory?
Here are some of the ways:
Nostalgia isn't just for old folks. Sure, it's been 20 years since the 1994 original, but it's been in near-constant rotation on cable ever since. A whole generation has grown up watching the silly antics of Carrey and Jeff Daniels as the doofus duo. »
- Gary Susman
1-20 of 250 items from 2014 « Prev | Next »
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The three big international crises – Ukraine/Russia, Israel/Gaza and Iran/nuclear – mark a choice for President Obama, stick with Israel and the old alignments or shift toward more cooperation with Russia and Iran. But the pieces on this global chessboard are fast moving, says ex-CIA analyst Paul R. Pillar.
Tag Archive for Russia
NYT Protects the Fogh Machine
Exclusive: In crises ranging from the Iraq War to civil conflicts in Syria and Ukraine, the New York Times has steadily transformed itself into a propaganda organ, promoting false U.S. government narratives rather than providing objective information to its readers, as Robert Parry observes again.
Itching for a Genocide
Exclusive: A meeting of French, German, Russian and Ukrainian foreign ministers sought a new ceasefire in Ukraine, but the U.S. State Department and the mainstream U.S. media seem eager for more bloodshed, an unseemly rush into a war that could become genocide, writes Robert Parry.
The Risk of a Ukraine Bloodbath
Exclusive: Pressured by neocons and the mainstream U.S. media, the Obama administration is charting a dangerous course by seeking a military solution to Ukraine's political crisis and possibly provoking Moscow to intervene to protect ethnic Russians, ex-CIA analyst Ray McGovern warns.
Who Violated Ukraine's Sovereignty?
Exclusive: The West has accused Russia of violating a 1994 pledge to respect Ukraine's sovereignty in exchange for its surrender of Soviet-era nuclear weapons. But the West's political and economic interference might also represent a violation, says ex-CIA analyst Ray McGovern.
NYT Revamps Its False Ukraine Narrative
Exclusive: Official Washington's Ukraine narrative has been that it was all Vladimir Putin's fault, that the Russian president staged the crisis to restore the Russian empire, a storyline that never made sense and is now being rearranged to explain why Putin is seeking peace, writes Robert Parry.
Obama's True Foreign-Policy 'Weakness'
Special Report: President Obama has shied away from confronting Washington's neocons who continue to exercise undue influence at think tanks, on op-ed pages and even inside Obama's administration. With the new Iraq crisis, Obama's timidity is coming back to haunt him, writes Robert Parry.
Obama at a Crossroad of War or Peace
Exclusive: The dramatic spread of Sunni extremism into the heart of Iraq may force President Obama to finally make a choice between simply extending a slightly less violent Bush Doctrine and charting his own innovative course in the name of peace, Robert Parry writes.
Iran Offers Scaled-Back Nuke Program
To seal a deal with world powers, Iran has agreed to structure its nuclear enrichment in ways only useful for generating electricity, but that still might not satisfy U.S. negotiators, writes Gareth Porter from Tehran for Inter Press Service.
The Only Standards Are Double Standards
Exclusive: President Obama is still embracing Official Washington's false narrative on Ukraine as he hypocritically blames the crisis entirely on Moscow and ignores the West's role in toppling an elected president and provoking a nasty civil war, writes Robert Parry.

subset: commoncrawl


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Court asked to keep teen arrested in deputy's death locked up longer
PROVO — Prosecutors say it could be another three weeks before they consider filing charges against a 17-year-old girl who was arrested in connection with the shooting death of a Utah County sheriff's sergeant.
On Jan. 30, Sgt. Cory Wride, 44, was shot and killed in Eagle Mountain after stopping to help what he thought was a stranded motorist. The ensuing chase between the two suspects and multiple police agencies stretched over 50 miles through two Utah counties, resulted in the shooting of a second deputy, shots being fired at four different locations, a carjacking, and ultimately a shootout with police that resulted in the death of Jose Angel Garcia-Juaregui, 27.
The teenage girl is suspected of driving the car during the crime spree with Garcia-Juaregui and was taken into custody. She was not injured in the shootings.
The teen has been held in a juvenile detention facility in Provo since that day while investigators determine whether she played an active role in the incidents or if she was being held hostage by Garcia-Juaregui.
The girl's name had not been released, nor have investigators talked about her connection to Garcia-Juaregui.
Deputy Utah County attorney Chris Yannelli on Wednesday filed a motion in 4th District Juvenile Court requesting that the 17-year-old be held in the detention facility for an additional three weeks while his office continues to comb through the evidence and determine what, if any, charges to file.
"I've asked for an additional period of 21 days, which would include amassing the evidence and filing charges at that time," he said.
Because of the extensive crime scene and the number of witnesses that need to be interviewed and medical reports that need to be studied, Yannelli said it is impossible to review it all in the standard time it normally takes.
According to the request for detention, the teen is being held as "a suspect in several pending felonies," Yannelli said. He declined, however, to specify which felonies she could face.
A juvenile court judge is expected to decide Friday whether to grant the extension.
Last week, Utah County Sheriff Jim Tracy said detectives were not certain whether the teen or Garcia-Juaregui shot Wride and deputy Greg Sherwood. Investigators planned to enhance video from Wride's patrol car dashboard camera to help determine that.
Yannelli said Thursday, however, it appears that Garcia-Juaregui was the person who shot Wride.
"At this point it doesn't appear that (the girl) was the shooter. It appears that she was the driver of the car," he said, while noting that video evidence still needs to be reviewed.
Once the investigation is completed and the Utah County Attorney's Office determines what charges are appropriate, Yannelli said his office will also decide whether to seek to have her certified to stand trial as an adult.
A funeral for Wride was held Wednesday, the same day that Sherwood underwent successful surgery to remove a bullet from his head. Police say they expect he will go home soon.
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text: Swedish Open Live Streaming - Saturday, February 4 Visit Bet365 Save For Later by Live Streaming Sport StaffPosted Nick Matthew (blue shirt) of England and Daryl Selby (white shirt) of England in action during their Quarter Final match in the ISS Canary Wharf Squash Classic at East Winter Gardens on March 23, 2011 in London, England. (credit: Dean Mouhtaropoulos/Getty Images) Share: 0 2 0 Get Squash Alerts Daryl Selby will be looking to keep up his fine run of form when he takes on Karim Darwish in the semi-finals of the Swedish Open on Saturday.Watch & bet on the Swedish Open at Bet365 > live streaming > squash The Case Swedish Open 2012 is being held in Linkoping from Thursday, February 2 until Sunday, February 5 with $70,000 up for grabs in prize money.Selby, who defeated fourth seed Thierry Lincou in the opening round, booked his place in the semi-finals with win over German Simon Rosner.Selby will now face number two seed Karim Darwish for a place in the final after the Egyptian saw off Swiss star Nicolas Mueller.The second semi-final sees number one seed Gregory Gaultier go up against England star and number three seed Peter Barker.Gaultier took just 26 minutes to see off England's Tom Richards in his quarter-final clash on Friday, while Barker needed 32 minutes to defeat Stephen Coppinger from South Africa.To watch live streaming coverage from the Swedish Open just follow these simple steps:Go to Bet365 & Sign-inSelect Bet365 > live streaming > squashWatch the Swedish Open Live OnlineSwedish Open Order of Play:12:45 - Karim Darwish vs Daryl Selby14:45 - Gregory Gaultier vs Peter Barker Watch live sport at Bet365 Read our Bet365 review 365 streams live to all members. 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Swedish Open final live streaming - Matthew v GaultierTop seeds Nick Matthew and Gregory Gaultier will contest the 2013 Case Swedish Open final on Sunday afternoon.... Case Swedish Open live streaming - Saturday, February 2It's semi-final day at the Case Swedish Open in Linköping and as expected, top seeds Nick Matthew, Gregory Gaultier and Peter Barker are all still in contention.... Swedish Open Squash Live StreamingThe Case Swedish Open continues this weekend with all the action being streamed live from the Linkoping Sporthall.... How to watch the Case Swedish Open live onlineThe 10th edition of the Case Swedish Open kicks off at the all-glass court at Linköping Sporthall on Thursday.... Swedish Open Live Streaming - Sunday, February 5The top two seeds will contest the Swedish Open on Sunday with Gregory Gaultier and Karim Darwish ready to do battle.... 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October 2010, Volume 343, Issue 1-2, pp 211-216
Date: 19 Jun 2010
Endothelial arginase II responds to pharmacological inhibition by elevation in protein level
- Karina Krotova,
- Jawaharlal M. Patel,
- Edward R. Block,
- Sergey Zharikov
- … show all 4 hide
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Arginase is an enzyme which converts arginine to ornithine and urea. Recently, arginase has been implicated in many physiological and pathological processes including vascular diseases. Inhibition of arginase activity by pharmacological inhibitors is a useful tool to study the biology of arginases and their possible role in therapy. There are several arginase-specific inhibitors commercially available. Herein, we show that some of these inhibitors lead to an increase in arginase II protein level and activity. These effects should be anticipated when these inhibitors are in use or during the testing of new arginase inhibitors.
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- Tenu J-P, Lepoivre M, Moali C, Brollo M, Mansuy D, Boucher J-L (1999) Effects of the new arginase inhibitor N[omega]-hydroxy-nor-arginine on NO synthase activity in murine macrophages. Nitric Oxide 3:427–438 CrossRef
- Block ER, Patel JM, Sheridan NP (1986) Endotoxin protects against hyperoxic decrease in membrane fluidity in endothelial cells but not in fibroblasts. Lab Invest 54:146–153
- Markwell MAK, Haas SM, Bieber LL, Tolbert NE (1978) A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem 87:206–210 CrossRef
- Larson E, Howlett B, Jagendorf A (1986) Artificial reductant enhancement of the Lowry method for protein determination. Anal Biochem 155:243–248 CrossRef
- Corraliza IM, Campo ML, Soler G, Modolell M (1994) Determination of arginase activity in macrophages: a micromethod. J Immunol Methods 174:231–235 CrossRef
- Zharikov S, Krotova K, Hu H, Baylis C, Johnson RJ, Block ER, Patel J (2008) Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells. Am J Physiol Cell Physiol 295:C1183–C1190 CrossRef
- Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-[Delta][Delta]CT method. Methods 25:402–408 CrossRef
- Vockley JG, Jenkinson CP, Shukla H, Kern RM, Grody WW, Cederbaum SD (1996) Cloning and characterization of the human type II arginase gene. Genomics 38:118–123 CrossRef
- Morris SM, Bhamidipati D, Kepka-Lenhart D (1997) Human type II arginase: sequence analysis and tissue-specific expression. Gene 193:157–161 CrossRef
- Boess F, Kamber M, Romer S, Gasser R, Muller D, Albertini S, Suter L (2003) Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems. Toxicol Sci 73:386–402 CrossRef
- Chrzanowska A, Krawczyk M, Baranczyk-Kuzma A (2008) Changes in arginase isoenzymes pattern in human hepatocellular carcinoma. Biochem Biophys Res Commun 377:337–340 CrossRef
- Reczkowski RS, Ash DE (1994) Rat liver arginase: kinetic mechanism, alternate substrates, and inhibitors. Arch Biochem Biophys 312:31–37 CrossRef
- Colleluori DM, Morris SM, Ash DE (2001) Expression, purification, and characterization of human type II arginase. Arch Biochem Biophys 389:135–143 CrossRef
- Kuhn NJ, Ward S, Piponski M, Young TW (1995) Purification of human hepatic arginase and its manganese (II)-dependent and pH-dependent interconversion between active and inactive forms: a possible pH-sensing function of the enzyme on the ornithine cycle. Arch Biochem Biophys 320:24–34 CrossRef
- Colleluori DM, Ash DE (2001) Classical and slow-binding inhibitors of human type II arginase. Biochemistry 40:9356–9362 CrossRef
- Title
- Endothelial arginase II responds to pharmacological inhibition by elevation in protein level
- Journal
Molecular and Cellular Biochemistry
Volume 343, Issue 1-2 , pp 211-216
- Cover Date
- 2010-10-01
- 10.1007/s11010-010-0515-5
- Print ISSN
- 0300-8177
- Online ISSN
- 1573-4919
- Publisher
- Springer US
- Additional Links
- Topics
- Keywords
- Arginase
- Arginase inhibitors
- Endothelium
- Industry Sectors
- Authors
- Karina Krotova (1)
- Jawaharlal M. Patel (1) (2)
- Edward R. Block (1) (2)
- Sergey Zharikov (1)
- Author Affiliations
- 1. Department of Medicine, University of Florida, MSB Room M452, Gainesville, FL, 32610, USA
- 2. Research Service, VA Medical Center, Gainesville, FL, USA


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Memphis is More than You Think: The Great Outdoors
Walking in Memphis is more than a song - it's a way of life. Thousands of acres of public parks are home to dense forests, open fields, fish-filled lakes and winding rivers giving just about every major neighborhood in Memphis access to a park or trail.
Go ahead, indulge in Memphis barbecue - you can easily walk it off on the Shelby Farms Greenline. This former 7-mile railroad line connects the heart of Midtown to Shelby Farms (one of the largest urban green spaces in the U.S.). The flat, smooth, quiet and mostly shaded route is perfect for walkers, bikers and skaters. The trail is open from sunrise to sunset.
The fun doesn't stop there. Shelby Farms Park also offers horseback riding, 20 lakes for fishing and paddle-boating, a disc-golf course, picnic pavilions, awesome playgrounds, an off-leash dog park, bicycle and walking trails, and even a herd of American bison.
Located in Millington, about 13 miles north of Downtown Memphis along the Mississippi River, Meeman-Shelby Forest State Park is more than 13,000 acres of hardwood forests. This state park boasts outdoor amenities like two fishing lakes, one of the largest disc golf courses in the Southeast, a nature center, miles of biking, hiking and horse trails along with ranger-led canoe programs. Staying overnight? Consider park cabins or the new online camping reservation system. And you'll definitely want to stop by the Shelby Forest General Store for a soda pop and one of their famous cheeseburgers.
Home to the Memphis Zoo and Old Forest Arboretum (many trees in this area are over 300 years old), Overton Park is 184 acres of public parkland including a nine-hole golf course, two play areas, a dog park and a 2.5 mile winding and paved shared use path. Put the pedal to the pavement, enjoy the shaded paths and have lunch in the park. In Overton Park you'll also find an outdoor Levitt Shell Theater where Elvis Presley gave his first performance.
Scheduled for completion in 2015, the $30 million Harahan Bridge Project is one of the region's most ambitious and impressive bike projects to date. Connecting Downtown Memphis, with West Memphis, Ark., it will soon be possible for bikers to cross the Mississippi River over the 100-yr old Harahan Bridge. For more information about the Harahan Bridge Project, follow their progress online.
Need more biking options in the cradle of the Blues? Check out this big map of Memphis bike lanes, shared use roads and bike trails.
The Memphis Botanic Garden definitely welcomes busy little bodies. Part playground, part children's museum, part outdoor art gallery, you can only imagine the fun you can having playing in this kid's backyard - My Big Backyard. With outdoor areas named Playhouse Lane, Critter Creek, Wormvill and Treetop Adventure, My Big Backyard is great for running, digging, splashing and discovering the great outdoors.
And about the rivers – navigating the Mississippi or Wolf through city and wilds is an adventure for the books. Mud Island River Park and area outfitters will gear you with canoes, kayaks, stand-up paddleboards – and guides, should you want one.
Now that you've got the jist of all that Memphis has to offer in terms of outdoor amenities, start planning your trip by visiting MemphisTravel.com to search for attractions, find the perfect restaurant and scope events that are just right for you and your crew.


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Vanderbilt hits the road for the second week in a row Saturday when the Commodores travel to Ole Miss. The game will begin at 6 p.m. CT and will be televised by ESPNU.
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Brothers jailed for conspiring to attend terror training camp in Syria
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Google has been told to improve its privacy policies or face enforcement action by the UK data watchdog.
The Information Commissioner's Office (ICO) said the US multinational's updated privacy policy has raised "serious questions" about its compliance with the UK Data Protection Act.
The warning came after similar announcements were made by several other data protection authorities, including in France and Spain.
An ICO spokesman said: "We have today written to Google to confirm our findings relating to the update of the company's privacy policy. In our letter we confirm that its updated privacy policy raises serious questions about its compliance with the UK Data Protection Act.
"In particular, we believe that the updated policy does not provide sufficient information to enable UK users of Google's services to understand how their data will be used across all of the company's products.
"Google must now amend their privacy policy to make it more informative for individual service users.
"Failure to take the necessary action to improve the policies compliance with the Data Protection Act by September 20 will leave the company open to the possibility of formal enforcement action."
The move comes after the ICO ordered Google to destroy four discs containing information it unlawfully took from unsecured wifi networks using its Street View cars.
The ICO warned Google that failure to comply with the legal order would be considered contempt of court.
Google said it was immediately proceeding with plans to delete the data.
A group of EU data protection authorities recently wrote to Google seeking information about its new Google Glass device and how the company intends to ensure compliance with data protection laws.
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Local News
Sheriff's Department Investigates Burglary and Criminal Damage ComplaintThe Marion County Sheriff's Department is investigating a burglary to a hunting shed on the Vermundy Road in rural Kinmundy. Randy Wooden of Freemont Street in Kinmundy reported numerous items were stolen, including tools, a deer camera, computer and monitor, space heater, extension cords and stereo equipment. He reported entry was made by breaking out a window. Wooden said the burglary occurred sometime since Monday.
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|By John A. Barry
Article Rating:
|January 12, 2006 07:30 AM EST
The "town" in this case was Redwood Shores, CA, or, more specifically, Oracle's Oz-like campus within that city's confines. The "hall" was Oracle's conference center.
Because the presentation was pitched primarily at employees of Sun and Oracle, the two chiefs, known for their aggressive stances, were in a jovial, frequently joking mood. Oracle's Larry Ellison (pictured) came off as the funnier and more amped up of the two. Sun's Scott McNealy seemed uncharacteristically subdued, perhaps because he wasn't on his own turf. He even joked that Sun lacks a capacious venue like Oracle's conference center, which was why he was in Redwood Shores.
Watch McNealy and Ellison on SYS-CON.TV
Employees of the two companies comprised most of the several-hundred strong that filled the center, and the message to them was:
* Take your Oracle/Sun counterpart to lunch
* Hammer the competition
* Prefer Oracle on Sun (over IBM)
* Java Rules, .Net drools
After both confirmed that Oracle was not buying Sun, McNealy did say, "We're on the same side, on the same team." The two men then brought the audience back to the 1980s, extolling the virtues of open systems and standards.
Interestingly, Ellison, more than McNealy, emphasized the "open" message, even though Sun had first staked out that territory with "Open Systems for Open Minds" campaign, launched 20 years ago. "We're betting that standards win," said the Oracle chief.
As part of their mutual initiative, Sun Ultra Sparc 4 models will come with Oracle bundled "free"--"going for share," as McNealy termed this arrangement. Buyers may elect to receive the software by agreeing to buy a one-year service contract from Oracle. Ellison assured the audience that Oracle sales reps will receive a commission on each such bundle.
|Bill H. 01/19/06 12:05:40 PM EST
Ellison was funnier than Scott??? By what measure?
|Technology Tuesday 01/12/06 09:13:08 AM EST
How often do 3 of the Valley's biggest superstars make public apperarances on the same day: Steve Jobs of Apple, Scott McNealy of Sun Microsystems and Larry Ellison of Oracle...incredible.
|InOtherNews 01/12/06 09:09:10 AM EST
'Sun CEO Scott McNealy started Tuesday's "town meeting" session for media and employees at Oracle headquarters by dispelling rumors that the two companies might be poised to announce a merger. But when he turned to Oracle CEO Larry Ellison for confirmation, he only heard hems and haws.' That was eWeek's take.
|Oracle-Sun vs Apple 01/12/06 08:41:06 AM EST
Whats it all mean? The answer surely is simple: it means that Steve Jobs was getting all the attention because of Apple's sales reaching $5.7 billion last quarter, outstripping the company's $4.7 billion prediction as demand soared for iPod music players and Macintosh computers.
This was the Sun-Oracle answer. But the Apple numbers deservedly got 100x more attention.
|NZheretic 01/12/06 08:21:00 AM EST
It makes a lot of sense for Sun to open source the Java Libraries and Solaris Kernel.
|fm6 01/12/06 08:19:11 AM EST
I find it hard to believe that Sun can create software that's so good, people will buy Sun hardware just to run it. And if it's open source, they probably won't need Sun hardware to run it
|No Surprise 01/12/06 08:16:32 AM EST
||| Oracle's Larry Ellison came off as the funnier and more amped up of the two |||
McNealy's too clever by half, and humor has to be scripted for him. Larry's funny on the fly.
|Sun-Oracle 01/12/06 08:04:30 AM EST
So Larry's not gonna buy out Scottie? oh well...Bill's heart must have stopped there just for a moment. It seems he'll continue to be King Pin however for a goodly while yet.
|QuoteUnquote 01/12/06 07:50:41 AM EST
McNealy (commenting on Oracle's plush auditorium): "We don't have a room like this. The hardware business has lower margins, I think. ... So, Larry, are you buying Sun?"
|JDJ News Desk 01/11/06 01:26:44 AM EST
Because the presentation was pitched primarily at employees of Sun and Oracle, the two chiefs, known for their aggressive stances, were in a jovial, frequently joking mood. Oracle's Larry Ellison came off as the funnier and more amped up of the two. Sun's Scott McNealy seemed uncharacteristically subdued, perhaps because he wasn't on his own turf. He even joked that Sun lacks a capacious venue like Oracle's conference center, which was why he was in Redwood Shores.
|JDJ News Desk 01/11/06 01:04:49 AM EST
Because the presentation was pitched primarily at employees of Sun and Oracle, the two chiefs, known for their aggressive stances, were in a jovial, frequently joking mood. Oracle's Larry Ellison came off as the funnier and more amped up of the two. Sun's Scott McNealy seemed uncharacteristically subdued, perhaps because he wasn't on his own turf. He even joked that Sun lacks a capacious venue like Oracle's conference center, which was why he was in Redwood Shores.
One of the biggest challenges when developing connected devices is identifying user value and delivering it through successful user experiences. In his session at Internet of @ThingsExpo, Mike Kuniavsky, Principal Scientist, Innovation Services at PARC, described an IoT-specific approach to user experience design that combines approaches from interaction design, industrial design and service design to create experiences that go beyond simple connected gadgets to create lasting, multi-device experiences grounded in people's real needs and desires.
Nov. 26, 2014 01:15 PM EST Reads: 729
We are reaching the end of the beginning with WebRTC, and real systems using this technology have begun to appear. One challenge that faces every WebRTC deployment (in some form or another) is identity management. For example, if you have an existing service – possibly built on a variety of different PaaS/SaaS offerings – and you want to add real-time communications you are faced with a challenge relating to user management, authentication, authorization, and validation. Service providers will want to use their existing identities, but these will have credentials already that are (hopefully) i...
Nov. 26, 2014 01:00 PM EST Reads: 696
The Internet of Things will greatly expand the opportunities for data collection and new business models driven off of that data. In her session at @ThingsExpo, Esmeralda Swartz, CMO of MetraTech, discussed how for this to be effective you not only need to have infrastructure and operational models capable of utilizing this new phenomenon, but increasingly service providers will need to convince a skeptical public to participate. Get ready to show them the money!
Nov. 26, 2014 01:00 PM EST Reads: 698
"Matrix is an ambitious open standard and implementation that's set up to break down the fragmentation problems that exist in IP messaging and VoIP communication," explained John Woolf, Technical Evangelist at Matrix, in this SYS-CON.tv interview at @ThingsExpo, held Nov 4–6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Nov. 26, 2014 01:00 PM EST Reads: 520
The Internet of Things will put IT to its ultimate test by creating infinite new opportunities to digitize products and services, generate and analyze new data to improve customer satisfaction, and discover new ways to gain a competitive advantage across nearly every industry. In order to help corporate business units to capitalize on the rapidly evolving IoT opportunities, IT must stand up to a new set of challenges. In his session at @ThingsExpo, Jeff Kaplan, Managing Director of THINKstrategies, will examine why IT must finally fulfill its role in support of its SBUs or face a new round of...
Nov. 26, 2014 01:00 PM EST Reads: 572
Cultural, regulatory, environmental, political and economic (CREPE) conditions over the past decade are creating cross-industry solution spaces that require processes and technologies from both the Internet of Things (IoT), and Data Management and Analytics (DMA). These solution spaces are evolving into Sensor Analytics Ecosystems (SAE) that represent significant new opportunities for organizations of all types. Public Utilities throughout the world, providing electricity, natural gas and water, are pursuing SmartGrid initiatives that represent one of the more mature examples of SAE. We have s...
Nov. 26, 2014 01:00 PM EST Reads: 586
Connected devices and the Internet of Things are getting significant momentum in 2014. In his session at Internet of @ThingsExpo, Jim Hunter, Chief Scientist & Technology Evangelist at Greenwave Systems, examined three key elements that together will drive mass adoption of the IoT before the end of 2015. The first element is the recent advent of robust open source protocols (like AllJoyn and WebRTC) that facilitate M2M communication. The second is broad availability of flexible, cost-effective storage designed to handle the massive surge in back-end data in a world where timely analytics is e...
Nov. 26, 2014 12:30 PM EST Reads: 346
Scott Jenson leads a project called The Physical Web within the Chrome team at Google. Project members are working to take the scalability and openness of the web and use it to talk to the exponentially exploding range of smart devices. Nearly every company today working on the IoT comes up with the same basic solution: use my server and you'll be fine. But if we really believe there will be trillions of these devices, that just can't scale. We need a system that is open a scalable and by using the URL as a basic building block, we open this up and get the same resilience that the web enjoys.
Nov. 25, 2014 09:30 PM EST Reads: 1,134
The Internet of Things is tied together with a thin strand that is known as time. Coincidentally, at the core of nearly all data analytics is a timestamp. When working with time series data there are a few core principles that everyone should consider, especially across datasets where time is the common boundary. In his session at Internet of @ThingsExpo, Jim Scott, Director of Enterprise Strategy & Architecture at MapR Technologies, discussed single-value, geo-spatial, and log time series data. By focusing on enterprise applications and the data center, he will use OpenTSDB as an example t...
Nov. 25, 2014 09:30 PM EST Reads: 1,187
P2P RTC will impact the landscape of communications, shifting from traditional telephony style communications models to OTT (Over-The-Top) cloud assisted & PaaS (Platform as a Service) communication services. The P2P shift will impact many areas of our lives, from mobile communication, human interactive web services, RTC and telephony infrastructure, user federation, security and privacy implications, business costs, and scalability. In his session at @ThingsExpo, Robin Raymond, Chief Architect at Hookflash, will walk through the shifting landscape of traditional telephone and voice services ...
Nov. 25, 2014 08:00 PM EST Reads: 1,385
The Domain Name Service (DNS) is one of the most important components in networking infrastructure, enabling users and services to access applications by translating URLs (names) into IP addresses (numbers). Because every icon and URL and all embedded content on a website requires a DNS lookup loading complex sites necessitates hundreds of DNS queries. In addition, as more internet-enabled 'Things' get connected, people will rely on DNS to name and find their fridges, toasters and toilets. According to a recent IDG Research Services Survey this rate of traffic will only grow. What's driving t...
Nov. 25, 2014 07:00 PM EST Reads: 1,240
Enthusiasm for the Internet of Things has reached an all-time high. In 2013 alone, venture capitalists spent more than $1 billion dollars investing in the IoT space. With "smart" appliances and devices, IoT covers wearable smart devices, cloud services to hardware companies. Nest, a Google company, detects temperatures inside homes and automatically adjusts it by tracking its user's habit. These technologies are quickly developing and with it come challenges such as bridging infrastructure gaps, abiding by privacy concerns and making the concept a reality. These challenges can't be addressed w...
Nov. 25, 2014 04:30 PM EST Reads: 1,272
Explosive growth in connected devices. Enormous amounts of data for collection and analysis. Critical use of data for split-second decision making and actionable information. All three are factors in making the Internet of Things a reality. Yet, any one factor would have an IT organization pondering its infrastructure strategy. How should your organization enhance its IT framework to enable an Internet of Things implementation? In his session at Internet of @ThingsExpo, James Kirkland, Chief Architect for the Internet of Things and Intelligent Systems at Red Hat, described how to revolutioniz...
Nov. 24, 2014 07:00 PM EST Reads: 1,598
Bit6 today issued a challenge to the technology community implementing Web Real Time Communication (WebRTC). To leap beyond WebRTC's significant limitations and fully leverage its underlying value to accelerate innovation, application developers need to consider the entire communications ecosystem.
Nov. 24, 2014 12:00 PM EST Reads: 1,477
The definition of IoT is not new, in fact it's been around for over a decade. What has changed is the public's awareness that the technology we use on a daily basis has caught up on the vision of an always on, always connected world. If you look into the details of what comprises the IoT, you'll see that it includes everything from cloud computing, Big Data analytics, "Things," Web communication, applications, network, storage, etc. It is essentially including everything connected online from hardware to software, or as we like to say, it's an Internet of many different things. The difference ...
Nov. 24, 2014 11:00 AM EST Reads: 1,616
Cloud Expo 2014 TV commercials will feature @ThingsExpo, which was launched in June, 2014 at New York City's Javits Center as the largest 'Internet of Things' event in the world.
Nov. 24, 2014 09:00 AM EST Reads: 1,629
SYS-CON Events announced today that Windstream, a leading provider of advanced network and cloud communications, has been named "Silver Sponsor" of SYS-CON's 16th International Cloud Expo®, which will take place on June 9–11, 2015, at the Javits Center in New York, NY. Windstream (Nasdaq: WIN), a FORTUNE 500 and S&P 500 company, is a leading provider of advanced network communications, including cloud computing and managed services, to businesses nationwide. The company also offers broadband, phone and digital TV services to consumers primarily in rural areas.
Nov. 23, 2014 07:30 PM EST Reads: 1,817
"There is a natural synchronization between the business models, the IoT is there to support ," explained Brendan O'Brien, Co-founder and Chief Architect of Aria Systems, in this SYS-CON.tv interview at the 15th International Cloud Expo®, held Nov 4–6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Nov. 23, 2014 12:00 PM EST Reads: 1,750
The major cloud platforms defy a simple, side-by-side analysis. Each of the major IaaS public-cloud platforms offers their own unique strengths and functionality. Options for on-site private cloud are diverse as well, and must be designed and deployed while taking existing legacy architecture and infrastructure into account. Then the reality is that most enterprises are embarking on a hybrid cloud strategy and programs. In this Power Panel at 15th Cloud Expo (http://www.CloudComputingExpo.com), moderated by Ashar Baig, Research Director, Cloud, at Gigaom Research, Nate Gordon, Director of T...
Nov. 23, 2014 07:45 AM EST Reads: 1,776
ARMONK, N.Y., Nov. 20, 2014 /PRNewswire/ -- IBM (NYSE: IBM) today announced that it is bringing a greater level of control, security and flexibility to cloud-based application development and delivery with a single-tenant version of Bluemix, IBM's platform-as-a-service. The new platform enables developers to build ap...
Nov. 22, 2014 05:30 PM EST Reads: 1,572


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how much to service the stibili trek on a car
1 Answer
Hello, Thank you for your post. Sorry to hear you're having these issues with your steering. Unfortunately, because I am not a certified mechanic, I am unable to diagnose what you're experiencing with your vehicle. I would suggest taking your vehicle into your Chevy dealership as they are the best resource in determining what the problem is. Vanessa GM Customer Service
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Jerry and Ann Moss will be
presented the eighth annual Laffit Pincay Jr. Award during the Hollywood Gold
Cup program Saturday, July 9 at Hollywood Park.
Pincay, a member of racing's Hall
of Fame since 1975, will make the presentation between the fifth and sixth
The Pincay Award is presented annually to someone who has
served the sport with integrity, extraordinary dedication, determination and
"Racing owes the Mosses a debt of gratitude for keeping
Zenyatta in training for an extra year,'' said Pincay. "They have been huge
supporters of the sport for a long period of time and have continued to promote
racing in numerous ways.
"I was fortunate
enough to ride some winners for them during my career. They are very nice
people, great to be around and well respected by everyone in every way.''
One of Pincay's victories for the Mosses came aboard
Ruhlmann for trainer Charlie Whittingham in the 1989 Mervyn LeRoy Handicap in
what remains a stakes record 1:40 1/5 for the 1 1/16 miles.
The co-founder of
A&M Records with legendary musician Herb Alpert, Jerry Moss has been
involved as a thoroughbred owner since 1970, owning dozens of stakes winners
such as the aforementioned Ruhlmann, Fighting Fit, 2005 Kentucky Derby upsetter
Giacomo, Kudos, Sardula and Tiago.
However, Zenyatta
is undoubtedly the best horse the Mosses have ever campaigned.
Trained masterfully
by John Shirreffs, the remarkable mare became the first female to ever win the
Breeders' Cup Classic, rallying furiously in the final quarter of a mile under
regular jockey Mike Smith to prevail in 2009 at Santa Anita.
Returned to
training after a brief retirement to race as a 6-year-old, Zenyatta nearly
repeated in the Classic, missing by a nostril to Blame, but was still voted
Horse of the Year. The daughter of Street Cry retired with 19 victories in 20
starts and a female record $7,304,660 in earnings.
The Mosses and
Shirreffs were widely lauded for making Zenyatta accessible to the racing
public as she was often visited by fans at her Hollywood Park stable. The
entire Zenyatta team was given a Special Eclipse Award earlier this year.
In addition to his
involvement as an owner, Jerry Moss has served as a member of the California
Horse Racing Board since being appointed by former Governor Arnold
Schwarzenegger in 2003.
Ann Moss is an active
environmentalist and founder of the Dolphin Connection.
The Pincay Jr.
Award was introduced by Hollywood
Park in 2004 with esteemed
executive and racing publicist Bob Benoit the initial winner.
Trainer Noble
Threewitt was the recipient in 2005, while the Stute brothers — Mel and Warren
— shared the award in 2006. Owner/breeder Ellwood W. "Bud" Johnston, whose Old
English Rancho is one of the most storied names in California racing, won the award in 2007,
while distinguished steward Pete Pedersen was the recipient in 2008. Merlin
Volzke, who also had a noteworthy career as a steward, became the first former
jockey to win the award in 2009. The Oak Tree Racing Association was honored in
Everyone is always talking about how they want our...
Hey! The Breeders' Cup is only three weeks a...
Wynn Las Vegas released its first slate of Kentuck...
Street Cry, one of the world's most successf...
Displaying the gameness that he has become known f...
Stephen Chesney and Cory Hoffman's Calgary Cat exp...
Phil Sims and Jerry Namy's Don't Tell Sophia, a $1...
There can be no doubt that the best racing i...
Overview - Owned by WinStar Farm and Stonest...
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The big announcement Beyoncé promised fans through a teaser video posted on her YouTube page on Wednesday turned out to be the full 60-sec long commercial for the new 'Pepsi' campaign starring Mrs. Carter as unveiled worldwide at 9AM today, April 4.
The spot named "Mirrors", which according to USA Today will have been viewed by an estimate audience of 1 BILLION people by the time the campaign ends, features Beyoncé Knowles 'reliving her past and exploring her future while watching herself in a mirror dance to her new song, "Grown Woman"...', bringing back the Beyoncés from previous musical eras in their respective outfits, eg; "Single Ladies", "Deja Vu", "Bootylicious", -"Work It Out", "Crazy In Love", among others. The commercial is fierce! Actually I can't stop re-playing it right now. Pepsi got it so right hiring Beyoncé for their new campaign. She's gonna make 'em win big money, no doubt about that. Coke, who?, lol.
Oh, by the way, the new funky song used in the spot is entitled "Grown Woman", it's a Timbaland production, it will appear on Bey's upcoming 5th studio album (duh) and will hit iTunes worldwide for all B' fans to purchase next Monday, April 8th!
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Tue, Mar 9, 10 at 8:43
|they supposed to be in a darker spot for a few days or do I put them right back under lights? Haven't done for awhile, can't remember. TIA.
Follow-Up Postings:
|I guess it depends on the light. HID lights might cause excess wilting. You will probably have some wilting for a few days anyway but I doubt fluorescent lights would make it worse. Al
|Direct sun or halide lights should be avoided. If you are using standard shop lights I have never found it to be a problem but a day of no lights isn't going to hurt them either.
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NBA Recap: New York Knicks 96, Los Angeles Lakers 127 [PHOTOS]
March 26, 2014 4:34 PM EST
NBA Recap: New York Knicks 96, Los Angeles Lakers 127 [PHOTOS]
The Los Angeles Lakers had a rare blowout out win this season after running the visiting New York Knicks out of the Staplce Center with a huge 127-96 victory on Tuesday night.
The L.A. reserves did the damage on this one as Xavier Henry (22 points), Nick Young (20 points) and Kent Bazemore (18 points) all scored in double-figures off the bench. As a whole, the Lakers just 57.3 per cent from the field overall and hit 18-of-28 from behind the arc. The home team was so hot that they hit 51 points in the third quarter.
Knicks forward Carmelo Anthony had 29 points and Amare Stoudemire had 16 for the Knicks, which have lost back-to-back games after establishing their longest winning streak of the season.
View the slideshow for images of the NYK-LAL game on Tuesday.
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What I Know: Lessons from My 30 years of Quadriplegia
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At 11:15 p.m. on Friday, Sept. 23, 1983, the life of 18-year-old Barbara Turnbull changed drastically. Three armed robbers burst into the Mississauga Becker's store where she was working the late shift, shooting her and severing her spinal cord. Turnbull almost lost her life, but survived a quadriplegic. Now, as she marks the 30th anniversary of her injury, Turnbull — a Toronto Star reporter and the much-honoured founder of the Barbara Turnbull Foundation — looks back on her life as a disabled person, its frustrations and joys. What I know: Lessons from my 30 years of quadriplegia is a candid, moving and inspiring book about acceptance and turning adversity into activism.
What I Know: Lessons from My 30 Years of Quadriplegia is available Friday through the Star's weekly ebook program, Star Dispatches. Simply go to stardispatches.com and subscribe for $1/week. Single copies of What I Know are available for $2.99 at starstore.ca and itunes.com/stardispatches .
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What was meant for me will be Mine once again... THE CHAMP OF CHAMPS IS BACK
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.Adam Schefter @AdamSchefter 6m
ESPN about to carry Mike McCarthy press conference in which he will name the Packers starting QB for Sunday's winner-take-all vs. Chicago.
Broken collarbone, what a wuss.
OK Nick, here is what I need you do. Go over there and grab me some water, a towel, and make yourself comfortable while I WRECK THIS ISH.
My name is Mark Sanchez. I am here to save you.
Best question of the news conference:
"Coach, how much better do you like your chances with Rodgers?"
I wanna be a reporter and ask dumbass questions.
the baaaaaaaaaaaaaaaaaaad man that he is!
Best thing to come from this announcement?
A reporter asked Jay Cutler how he felt about Rodgers's return and responded:
"I play offense."
...though seriously, I'm cursing this news. Does anyone know a good Voodoo doctor/shaman I can send to **** up Rodgers's psyche a bit?
NFC North: Leading the League in Stupid.
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Great news, we don't want excuses from either side. If the Packers can respond in this type of pressure then they deserve to be in, if not, they obviously don't.
Barry Lamar Bonds. .393/.967/1.054....on 3-0 counts.
lol, Please' top 10 p4p: Mayweather/Marquez/Pacquiao/Bradley/Cotto/Wlad/Rigondeaux/Froch/Canelo/Maidana
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What was meant for me will be Mine once again... THE CHAMP OF CHAMPS IS BACK
The Dress "If" off?
You Too Can Achieve This When You Visit The Fitness Forum!
What was meant for me will be Mine once again... THE CHAMP OF CHAMPS IS BACK
Can we please edit this thread title? This is a legit news story. Not MTM's troll Rodgers Pro Favre Anti Ted Thompsonfest
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La Mimosa
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