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Research Topics
Genomes and Genes
Cellular signaling and Trafficking of APP Family Members
Principal Investigator: LUCIANO D'ADAMIO
Affiliation: Albert Einstein College of Medicine
Country: USA
Abstract: The familial Alzheimer's disease gene product amyloid Beta (ABeta) precursor protein (APP) is processed to generate ABeta which is considered to be one of the major culprits of Alzheimer's disease. APP is first processed extracellularly by the alpha- or Beta-secretase creating either a C83 or C99 membrane tether fragment, respectively, and then by the gamma-secretase in the transmembrane domain. Processing by the Beta- and gamma-secretase leads to production of ABeta as well as AID (APP Intracellular Domain) which is derived from APP's extreme carboxy terminus. AID was originally shown to lower the cellular threshold to apoptosis and more recently has been shown to modulate gene expression and cellular calcium homeostasis. APP is a member of a gene family that includes the APP like molecules APLP1 and APLP2. Studies using knock out mice have demonstrated that APP, APLP1 and APLP2 have partially redundant functions as well as unique roles. Since APP signals by releasing the biologically active AID peptide, it is possible that APLP1 and APLP2 also release biologically active APP Like Intracellular Domains ALIDs due to processing by the g-secretase. The major goals of the current proposal are to characterize the signaling pathways regulated by APP, APLP1 and APLP2 processing. These studies could unveil the signaling pathways that are either common or specific and unique to each APP family member. In this context, we will also study the trafficking of APP family members in primary neurons. The transport of APP in neurons may be of great relevance to the biological function of APP in neuronal ceils and may regulate neurite growth. These studies may clarify the biological role of APP family members and have important practical applications in the development of new compounds for the cure and or prevention of Alzheimer's disease.
Funding Period: 2003-04-15 - 2009-03-31
more information: NIH RePORT
Top Publications
Detail Information
- The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta productionShuji Matsuda
Albert Einstein College of Medicine, Bronx, NY 10461, USA
J Biol Chem 280:28912-6. 2005..Finding that BRI2 pathogenic mutations alter the regulatory function of BRI2 on A(beta)PP processing would define dysregulation of A(beta)PP cleavage as a pathogenic mechanism common to AD, FDD, and FBD...
- Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer diseaseChiara D'Ambrosio
Proteomics and Mass Spectrometry Laboratory, ISPAAM, National Research Council, 80147 Naples, Italy
Mol Cell Proteomics 5:97-113. 2006....
- BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrateShuji Matsuda
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
J Neurosci 28:8668-76. 2008..Alterations of BRI2 by gene targeting or transgenic expression regulate Abeta levels and AD pathology in mouse models of AD. Competitive inhibition of APP processing by BRI2 may provide a new approach to AD therapy and prevention...
- Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signalingDawang Zhou
Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA
J Alzheimers Dis 16:301-7. 2009..Our results indicate that phosphorylation of the cytoplasmic tail of AbetaPP on Tyr-682 represents a second mechanism, alternative to AbetaPP processing by secretases, that regulates AbetaPP/Fe65 downstream signaling pathways...
- BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2Shuji Matsuda
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 1046, USA
J Biol Chem 284:15815-25. 2009..Competitive inhibition of APP processing by BRI3 may provide a new approach to AD therapy and prevention...
- Generation and initial characterization of FDD knock in miceLuca Giliberto
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
PLoS ONE 4:e7900. 2009..The interaction between the two precursors, APP and BRI(2), and possibly between Abeta and ABri or ADan, could be important in influencing the rate of amyloid production or the tendency of these peptides to aggregate...


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Best Western Plus Burlington Inn & Suites is quite a large hotel in Burlington. These hotel rooms are rated with a 2 star category.
During your stay in Best Western Plus Burlington Inn & Suites you will get complimentary breakfast. Take a dive during your stay; there is an indoor swimming pool. Keep yourself beautiful; there is a spa tub available. Amongst the many services on offer at this accommodation are a dry cleaning/laundry service, a late check-out option and an express check-in/out service. At this property there are 3 meeting rooms. A business center is one of the facilities especially convenient for guests on business trips. With 78 rooms, there will surely be one of your liking.
Air conditioning at Best Western Plus Burlington Inn & Suites provides a more enjoyable climate. Calling to local destinations can be enjoyed at no extra cost. A housekeeping service is just one of the services that complement the rooms here. It is hard to imagine a life without Internet these days. For your stay in Burlington, wireless high-speed Internet access (complimentary) is offered. Bedding options include a pillowtop mattress. In the hotel you can find rooms that have a microwave but also a refrigerator and a coffee/tea maker.
Show reviews
|From 15:00 Check-out: Until 11:00
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|Paid Parking (Self-service)
|General facilities:
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subset: commoncrawl


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Latest Headlines
Thursday the Arkansas Department of Health confirmed 20 Arkansans have died ...
Cooler than average temperatures this week.
The No. 24 Arkansas baseball team (21-13) raced out to an early lead Wednesday ...
Due to the threat of inclement weather, Arkansas baseball's series opener with ...
Scottsdale, AZ (SportsNetwork.com) - The Oakland Athletics and Arizona
Diamondbacks played to a 8-8 10-inning Cactus League tie.
The starting pitchers for both teams struggled in this one.
Oakland's Sonny Cray was tagged for four runs and five hits in his lone inning
of work, while his Arizona counterpart, Trevor Cahill, allowed six runs and
eight hits over three innings.
Sam Fuld and Brandon Moss both homered off Cahill.
Gerardo Parra, Martin Prado and Alfredo Marte each had two RBI for Arizona.
The Sports Network


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56.6 mi (about 1 hour 49 mins)
Right a little competition... (as we did with the Ecamp 2006 Location)
Who is the closest?
Who is the furthest away?
Use this to work it out:
Change the start address field to your postcode or location. (the distance on that link is from the nearest village, Walesby)
Assistant Scout Leader | Group Trustee
4th Huddersfield Golcar Scout Group
District Media Development Manager
Huddersfield South West
Website coming soon!
56.6 mi (about 1 hour 49 mins)
Assistant Scout Leader | Group Trustee
4th Huddersfield Golcar Scout Group
District Media Development Manager
Huddersfield South West
Website coming soon!
264 mi (about 6 hours 21 mins)
Somebody actually complimented me on my driving today. They left a little note on the windscreen, it said 'Parking Fine.' So that was nice
256 mi (about 6 hours 33 mins)
Richard Fairbairn
Escouts Management
Group Scout Leader - 14th Midlothian Bonnyrigg Scout Group
Personal Website ; Twitter ; Facebook
Twitter: http://www.twitter.com/escouts
Facebook: http://www.facebook.com/escoutsofficial
66.3 miles 1hr 45 mins.
Last time I went to Walesby it only took us about 1hour 15mins and NG22 is that much further away, does google expect you to drive at 30mph all the way !!!!
152 miles, 3hrs 39min - an average speed of 41 Mph
You can contact Mark via www.4theastcotescouts.org.uk
301 miles read it and weep
68.1 mi (about 1 hour 46 mins)
I've got to admit with you here Helen. It usually only takes us about 1 hour 20 mins tops to get to Walsby.
Phil Banyard
1st Haworth Scouts | Centenary Archery Team | Melton Scout Campsite
95.8 mi (about 2 hours 47 mins)
David Curtis
Escouts Moderator
Ecamp2009 - All the way with the epolice
Ecamp2008 - All the way
Ecamp2006 - (well for 1 night may be)
SL & AGSL - 1st Woodford Halse
Webmaster of
Please make all support requests to the forum or the helpdesk
218 mi (about 5 hours 1 min)
372 (about 9 hours 25min)
What do you care what other people think! - Richard P. Feynman
A person needs only three tools in life: WD-40, duct tape and a hammer. If it doesn't move and it should, use the WD-40. If it moves and it shouldn't, use the duct tape. If either doesn't work, use the hammer.
45.3 mi (about 1 hour 36 mins)
It normally only takes us about 1hr.
Stephen Goodfellow
(Scout Leader, GNAS Community Sports Leader, NSRA YPS Tutor)
189 mi (about 4 hours 30 mins)
59.3 miles (about 1 hour 35 mins)
Peter Andrews AESL of Headingley Friday ESU & ABSL and Webmaster of Falkoner Scout Group
Bookings Secretary - Wike, North Leeds District Campsite - www.wikecampsite.org.uk
Please note all views expressed are my own and not those of any organisation I'm associated with
110 mi (about 2 hours 50 mins)


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Ball being held to send special little boy to Disneyland Paris (From Salisbury Journal)
If you have a story call our newsdesk on 01722 426511 or email us. To advertise call 01722 426500.
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Ball being held to send special little boy to Disneyland Paris
10:00am Monday 7th April 2014 in New Forest News By Karen Bate
A SUMMER ball is being held in May to raise money for a little boy with a terminal wasting disease to go on a trip of a lifetime to Disneyland Paris.
Jon Tarrant-Heckford, above, has with Sanfilippo syndrome, which prevents the body removing waste and chemicals from the brain and nervous system.
The condition means he may not live beyond ten years old.
Wishes 4 Jon was set up to raise money to give Jon and his family some magical memories during their time together.
To date the family have been to Lapland and Marwell Zoo and now they are hoping the summer ball will raise enough finds to send them to Disneyland.
His mother Lorraine Tarrant said: "We just desperately want to take Jon to this magical world of make-believe, where we can make some more amazing memories and make this precious time with him unforgettable.
"Jon loves giggling and I imagine there will be lots of giggles in Disneyland. He will love the lights, the atmosphere and meeting all his favourite characters.
"The ball to raise money for Wishes 4 Jon is sure to be a wonderful occasion."
The summer ball is being held at Tyrells Ford Hotel, Avon on May 17.
Tickets are available at £35, to include three courses and live music, from Lorraine Tarrant Antiques on 01425 461123 or the Fox in the Forest on 07881 880273.
Comments are closed on this article.


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Autumn bazaar at South Perrott (From Chard & Ilminster News)
Get involved! Send your photos, video, news & views by texting CI NEWS to 80360 or email us
Autumn bazaar at South Perrott
6:00am Monday 12th November 2012 in News
AN autumn bazaar will be held at South Perrott village hall this Saturday, November 10, from 2.30pm.
All are welcome to attend and admission costs 20p.
Comments are closed on this article.


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There are few desserts as comforting as bread pudding that are as easy to make. This version from Napoleon Bistro features rum soaked raisins and a frothy sabayon sauce. We like to enjoy it with a steaming cup of buttered-rum … Keep reading
Tag Archives: Napoleon Bistro
Friday Night Bites: Tables for Two on Friday, March 1
Craving a romantic getaway? While you may not make it all the way to see the Eiffel Tower, why not enjoy some French food at one of our CityEats partner restaurants? We've gathered a list of some of our favorite French spots … Keep reading
Friday Night Bites: Tables for Two on March 16th
It's finally Friday, and in just a couple of hours, the weekend will be all yours. Why not treat yourself (and maybe a date) to dinner and drinks? Here, we've hand-picked a few of our fab restaurants that still have availability … Keep reading


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Beautiful Vacation Home on B Avenue in Coronado
- bedrooms 3
- baths 2½
- sleeps 6
- pool no
- hot tub no
- pets allowed yes
- type House
- community
- rates (USD) $ 5,000 - $ 12,000 / month
vacation rental description
Fantastic home in a very desirable location with a short walk to the
ocean, town and the Hotel Del Coronado. This relaxing home has an open floor plan which is perfect for entertaining your friends and family. Private front and back patio areas are delightful. Two stories with bedrooms up. Monthly only-no weekly rentals.
Available for longer term lease.
****accept credit card payments.
vacation rental location
property availability
- dates with deals
- unavailable dates
Last modified on 05-5-2014 at 11:31 PM.
email owner view full calendar
Molly Korson, Korson Properties Lic.#01379254 619-808-6610
house rental amenities
King bed in the master suite
Queen bed
Twin beds (2)
W/D/high end appliances and amenities
Cable/wireless high speed internet
Plasma TV (3)/DVRs
2 car garage
BBQ, bikes, beach toys, stroller.
Central A/C
Fully furnished/ 2 fireplaces
activities and attractions in Coronado San Diego Area
Coronado Beach
Restaurants in Coronado and San Diego downtown
Golfing (Coronado Golf Course)
Tourist attractions in San Diego
Proximity to Airport
vacation rental rates
Major Credit Cards accepted with fee
Seasonal rates apply
No Smoking/pet negotiable
Molly Korson, Korson Properties Lic.#01379254 619-808-6610
accepted payment methods
Prior to paying a reservation deposit, always verify payment instructions by calling the phone number displayed on this listing page. By contacting the owner directly and paying by an approved method - credit card, paypal, check or bank transfer - your reservation payment will be protected up to $1,000.Learn more in our Security Center


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Polar bears are ever more coming to be endangered due to many factors including industry projects, ice in their natural environment melting, as well as human aspect. By far the largest root cause is actually the change in the natural world of the polar bear. Numerous life-threatening situations are actually created for these cold climate bears when the ice melts. World-wide warming that is associated to industrialization as well as projects such as driving a car, burning coal, and more human projects causes the ice melting.
Ice melting must be actually a core focus of conservation energies for the polar bear as this is impacting the polar bear the most. Polar bears depend on huge stops of moving ice to perform their everyday actions connected to staying alive. Polar breeds prey on fat-laden seals from these stops of ice, they mate, and some also deliver their cubs on them. The issue by having the ice melting is that countless polar bears have gone hungry since there is not sufficient ice for them to hunt their prey. This impacts their capacity to reproduce as well as carry their cubs to term that instantly impacts human population numbers. Additionally, when ice is too a long way from land, polar bears will drown trying to swim a long way distances to find them. All of these issues have made the polar bear more land bound.
When polar bears are on land they are actually more likely to come face-to-face by having a predator, folks. Occasionally folks hunt polar bears as trophies and more individuals kill polar bears while defending themselves. People additional influence polar bears when companies construct facilities in their natural environment, thereby varying it irrevocably.
That Is actually Helping, and Exactly how
Significant contributors to the match to cut the Arctic Polar Bear provide the Coca-Cola Provider and the World Fauna Fund. Together these organizations are actually raising money to investigation which is creating global climate change as well as functioning with governmental agencies to manage greenhouse gasoline discharges. Additional significant projects provide energies to defend against unfavorable human interactions providing poaching and extreme tourism and defending crucial environment locations such as birthing dens.
One may get involved in the search to conserve the Arctic Polar Bears by working immediately with the World Wildlife Fund. Start your rewarding quest today by visiting Polar Bears at World Wild Life.


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Banksy mural withdrawn from sale
A Banksy mural at the centre of a controversial auction was withdrawn from sale at the 11th hour.
Slave Labour, which shows a young boy hunched over a sewing machine making Union Jack bunting, appeared on a wall in Wood Green, north London, last May, just before the Diamond Jubilee celebrations.
It disappeared from the side of the Poundland store last weekend and was due to be auctioned thousands of miles away in Miami last night, where it was expected to sell for up to £450,000.
But a spokesman for auction house Fine Art Auctions Miami (FAAM) confirmed that Slave Labour and Wet Dog, a second Banksy painting listed, had been withdrawn from sale. No reason was given.
– Claire Kober, Leader of Haringey Council
"It's a true credit to the community that their campaigning appears to have helped to stop the sale of this artwork from going ahead.
We will continue to explore all options to bring back Banksy to the community where it belongs."


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the best reviews
their picks
what to buy
Flashlights span the range from simple, basic light sources to sophisticated high-tech gadgets -- with prices over an equally wide range -- making choosing a flashlight trickier than it used to be. Some LED flashlights are now bright enough to replace traditional incandescent flashlights, and the best flashlights even use microprocessors or voltage regulators to boost efficiency. Some flashlights let the owner adjust the light to different levels, and voltage regulators keep the light consistent, even while the batteries drain. At the other extreme, cheap LED flashlights use switches that can break early, as well as poor-quality LEDs that can produce inconsistent or just plain weird light.
Consumer Reports magazine hasn't yet tested flashlights. For a time, FlashlightReviews.com more than made up for this absence, however, with comparison charts and top-ranked flashlights based on objective tests. The comparison charts are especially helpful because they include quite a few well-known incandescent flashlights. This site also provides detailed single-product reviews, including photos showing the light beam at about three feet. However, the author announced that he has stopped updating the site as of June 2007. Thus, while what's there is still relatively up-to-date, that will change over time. Another flashlight-enthusiast site, CPFReviews.com, covers fewer brands and models, but otherwise does a similarly excellent job. Especially noteworthy is a useful rating of each flashlight's "bang for the buck."
These two sites, like several others we review, abound in technical data. Less formal owner-written reviews and ratings provide a good balance, often comparing the output of a specific LED flashlight to one of the well-known MagLite flashlights. Amazon.com not only provides the largest number of owner-written flashlight reviews, but also makes them easy to browse by showing each flashlight's average rating right on the list of models.
You can still buy an ordinary 2D incandescent flashlight for about a dollar. As long as you keep plenty of replacement bulbs and batteries handy -- and if such a flashlight provides light that's bright enough for your tasks -- there's no need to pay more. However, experts and owners agree that for reliable light in emergencies -- for example, for a flashlight to keep in your vehicle -- it's worth paying more. The best LED flashlights are virtually unbreakable, can withstand heavy rain or even a dunk in water, and use high-quality LED modules that last 50,000 to 100,000 hours. Furthermore, LED flashlights with voltage regulators keep the light consistently bright even as the batteries fade, then shift to a lower level so you have plenty of time to replace the batteries.
Not surprisingly, expert reviews warn that cheap LED flashlights use poor-quality LEDs. This means the beam may be off-center or a strange color, and the phosphor coating that makes the LED produce white light may wear off early. For a trip to the bathroom at night, it may not matter. For a travel or emergency flashlight, however, experts recommend a waterproof, shock-resistant flashlight built for durability.
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As a pulmonologist and critical care physician Dr. Cayetano cares for patients with complex pulmonary issues both at Kadlec Regional Medical Center and at Kadlec Clinic.
Dr. Cayetano received her medical degree from the University of The East in Manila, Philippines. She relocated to the United States where she completed her Internal Medicine residency at the University of Connecticut, Farmington. She is Board Certified in Internal Medicine. Most recently she completed a clinical fellowship in Pulmonary Medicine & Critical Care at the University of California, Davis. She speaks
fluent English and Filipino.
Credentials: MD
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SEA is for passionate individuals who are interested in increasing the awareness in sustainable development. We act as a platform to introduce students to numerous research and job opportunities to allow them to gain a deeper understanding in this field.
We encourage everyone with an interest in sustainability to contact us for information on how to get involved with SEA.
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« New Music: Miguel f/ Kendrick Lamar – 'How Many Drinks? (Remix)'
Justin Timberlake Brings Memphis Soul to White House »
Bridget Kelly Celebrates Birthday with Jay-Z, Rita Ora, and Melanie Fiona
The Roc was in the building as Bridget Kelly celebrated her 27th birthday at the 40/40 Club in New York City last night. Friends and family came out to party with the "Special Delivery" singer, including her boss Jay-Z, mother, and fellow Roc girls Rita Ora and Melanie Fiona. Trey Songz, Adrienne Bailon, Timbaland, and Ne-Yo sipped D'USSE cocktails and snacked on red velvet cake.
"Love my boo ritaora too much fun last night," tweeted Bridget, who posed for a photo with her labelmate.
Bridget's debut is due later this year featuring Shea Taylor, Jerry Wonda, Ne-Yo, The-Dream, and Kendrick Lamar, who appears on the single "Street Dreamin.'"
See more pics of Bridget celebrating with her Roc Nation familia.
Photo credit: Johnny NunezTweet
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Group: Too Much Salt in Restaurant Food Center for Science in the Public Interest Finds Restaurant Meals Have Too Much Sodium WebMD Health News By Todd Zwillich Reviewed by Elizabeth...
Click here to read the full story.
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DALLAS -- The Texas Ballet Theater officially moved into the Winspear Opera House in downtown Dallas Friday night with a critically acclaimed production of "The Nutcracker."
The performance, however, was not without controversy.
Artistic director Ben Stevenson's production incorporates a large cast of more than 150, featuring dancers Kaitlyn Potts as Clara and Lonnie Weeks as the Nutcracker Prince.
There are great costumes, too, all set to Tchaikovsky's music.
But there are no musicians in the orchestra pit; the score to this ballet is pre-recorded. The ballet company says this is due to financial constraints.
The Dallas-Fort Worth Professional Musicians Association is protesting the decision, saying the acoustics of the Winspear are "squandered on canned music."
E-mail firstname.lastname@example.com


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Squeaky Shoes - Featured Shoe:
Squeaky shoes make great shoes for everyday wear or special occasions. They come in a variety of sizes and styles and are surprisingly affordable.
These adorable pink with black polka dot squeakers are a favorite of moms and toddlers everywhere. Place your order today and as always, all orders over $40 are shipped free of charge.


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Worker: Minimum Wage Bump Is 'A Big Deal'
August 1, 2014, CBS News
Report: Minnesota Ranks High for Well-Being of Kids; Improvement Needed
July 23, 2014, KSTP TV
Study: Minnesota No. 5 Best State For Children
July 23, 2014, WCCO TV
Minnesota Among the Nation's Best for Child Well-Being
July 22, 2014, Minnesota News Connection
Minnesota 5th, ND 6th in Kids Count ratings of child well-being
July 22, 2014, InForum
April 1, 2014,
Living in a prosperous state with a relatively vibrant economy, most Minnesotans believe in ensuring all children have what they need to succeed early and often in childhood so they can become productive adults. However, a new report called Race for Results: Building a Path to Opportunity for All Children, released April 1 by the Annie E. Casey Foundation, shows Minnesota needs to make some changes and investments to ensure that all kids – especially children of color – are poised to thrive. Learn Minnesota Race for Results Index Scores and about some programs that are removing barriers to success for many Minnesota children.


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The African Penguin (Spheniscus demersus, also known as the Jackass Penguin) is endemic to Southern Africa. They breed on twenty four islands and at three mainland sites along the coasts of South Africa and Namibia with 90% of the population being found in South Africa. The main breeding season is from March to May, with each female laying 1-2 eggs. Male and female pairs often remain together for a a number of years and return annually to the same nest site.
Penguin populations have declined dramatically from 1.5million adults in the 1930s to 160 000 in in the 1990s. Since the late 1970s, the colony on Dyer Island has dropped from 70 000 to only 2000 breeding pairs in 2005. This extreme drop is mainly due to egg exploitation and guano collection pre-1983. Reduced availability of food, seal predation, an increase in gull numbers and chronic oil pollution have also contributed largely. The collection of guano has had a catastrophic effect on the penguins' breeding habits. The age old nesting method involves burrowing into the guano to protect eggs and fledglings from sea-gull predation. When the majority of the guano is removed by man to be used as fertiliser, the penguins are forced to nest on open terrain which offers little or no protection from the Kelp Gulls, and causes nest abandonment by adults due to the higher temperatures that they experience from being in direct sunlight.
Dyer Island Cruises, in partnership with Cape Nature Conservation, initiated the Faces of Need Project in order to address this crisis. Artificial penguin nests are made out of fiberglass to mimic the guano burrows. These hollows provide shelter from the sun, protection from the gulls and thus vastly improve the penguins breeding success.
The Dyer Island Conservation Trust (DICT) was established for the conservation, rehabilitation and protection of the natural environment on Dyer Island and its surrounds. This includes fauna, flora and the biosphere, as well as implementation of environmental education and awareness. The trust uses funds raised and donated for these conservation purposes and aims to reverse the African Penguins population decline over the next four years by putting 2000 nest boxes on the island. The Grootbos Foundation wholeheartedly collaborates with Faces of Need and DICT through sponsorship and the promotion of the Trust and sales of penguin nests.
You can get involved by sponsoring a penguin nest for R400. This includes construction of the box, placement on Dyer Island, monitoring and penguin research. You will also be acknowledged with your name on our website, as well as on the supporters board at the Kleinbaai Harbour. Please visit www.dict.org.za for more information and donation details.


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BARCELONA, Spain (AP) -- For the second time in four days, Spanish leader Real Madrid conceded a late free kick as it slipped to a 1-1 draw at Villarreal marked by the sending off of an irate Jose Mourinho and two of his players.
The dramatic draw on Wednesday broke Madrid's 10-game away winning run and allowed Barcelona to close to within six points as the title race enters its home stretch with 10 games to play.
Like Malaga's Santi Cazorla did against Madrid on Sunday, Marcos Senna bent a free kick around the defensive wall to level in the 83rd, canceling out Cristiano Ronaldo's 62nd-minute opener for the visitors off an audacious assist by Mesut Oezil.
Mourinho, who had already been warned by the referee and had seen one of his assistants ejected for complaining, was banished in the 84th from the sideline in protest of the foul call that set up Senna's equalizer.
Madrid's Sergio Ramos and Oezil were both sent off with their second yellow cards a minute later as Madrid played the final five minutes with nine men.
Mourinho, along with his staff and players, refused to speak to the media after the match, but Ronaldo was heard shouting "It's a robbery, just a robbery" as he left the pitch shaking his head.
Villarreal gave a spirited performance on the debut of Miguel Angel Lotina, the troubled team's third coach of the season, and thanks to Senna's aim was rewarded with a hard-earned point that kept it four points above the drop.
Mourinho, whose side had struggled to win in its recent outings, sat Kaka on the bench and opted for a more muscular midfield with Xavi Alonso flanked by Sami Khedira and Lass Diarra.
But the opening stanza was anything but low tempo as both sides traded blows.
Nilmar had the hosts' best early chance in the 19th when he stole the ball from Ramos, only for goalkeeper Iker Casillas to better him one-on-one.
Mourinho decided he had seen enough after Senna came close with a long strike and sent on forward Jose Callejon for Diarra just before the half-hour mark.
The change, however, didn't give Madrid control as it continued to misfire while Villarreal kept up its frenetic push in search of the surprise.
Nor did Callejon last long. The former Espanyol player hurt his ankle and was replaced by Hamit Altintop at the beginning of the season half.
Madrid assistant coach Rui Faria was sent off, apparently for a comment made to the referee, in the 50th. It was the fourth time he has been ejected this season.
As "The Yellow Submarine" tired, Madrid settled down in defense and Ronaldo soon combined with Oezil, who had been quiet until then, to break through.
Ronaldo raced forward to meet Oezil's brilliant back-heeled pass, gained a better firing angle with one touch and rifled the ball beyond goalkeeper Diego Lopez for his 43rd goal in all competitions this campaign.
The Portugal forward has 33 goals in league play so far this season, one less than Barcelona's Lionel Messi.
But just like against Malaga, Madrid failed to finish off its adversary and a foul by Altintop outside the area gave Villarreal a chance that Senna did not waste.
The veteran Brazilian midfielder left Casillas flatfooted as he curled his right-footed shot around the wall and bounced it past the Spain goalkeeper into the net.
Chaos then broke out as Madrid lost its collective cool, and referee Jose Paradas sent Mourinho from the dugout in the 84th. Ramos followed his coach a minute later for a tackle near the halfway line and Oezil as well for complaining.
Paradas also banished Mourinho from a Copa del Rey match against Murcia in November 2010.
Also on Wednesday, it was: Zaragoza 2, Valencia 1; Real Sociedad 1, Levante 3; Atletico Madrid 2, Athletic Bilbao 1; and Sporting Gijon 2, Mallorca 3.
Messi scored a hat trick to become Barcelona's all-time scorer with 234 goals and lead the European champions to a 5-3 win over Granada on Tuesday, while Osasuna drew 0-0 at home to Getafe.
On Thursday, it's: Racing Santander vs. Sevilla, Real Betis vs. Espanyol and Malaga vs. Rayo Vallecano.


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Categories is a fun and simple pool game, good for all ages. Players choose items in a category and try to swim across the pool without being tagged.
⇒ Continue reading Categories…
This version of chicken is a pool game where players sit on each other's shoulders and try to knock other pairs over. A lot of fun (if somewhat rough and dangerous).
Bottle is a game played in a swimming pool: kind of like football, but in the water and with a clear two-liter bottle instead of a football. Best for teens and older, it's physically active and a lot of fun.
Watermelon is a fun pool game for older kids or teens. Basically like football, but in the water, and with a watermelon instead of a football. Doesn't that sound fun already?
⇒ Continue reading Watermelon…
Dibble dabble
Dibble dabble is a great game to play in the pool: fun, simple enough for younger kids, challenging enough for older kids, and, unlike some of my other favorite pool games, not overly rough/dangerous.
⇒ Continue reading Dibble dabble…
The human knot
A fun game for on land or in the pool, one I often played with siblings and cousins. Players stand in a circle, grab hands, and form a giant human knot that everyone tries to untangle together.


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By Playbill Staff
11 Apr 2014
|Photo by Joseph Marzullo/WENN
From the John Grisham courtroom drama A Time to Kill, adapted for the stage by Rupert Holmes, to Harvey Fierstein's new comedy Casa Valentina, the final new play of the season, here is an overview of the 12 plays that have opened or will open in time for the 2014 Tonys, which will take place June 8 at Radio City Music Hall.
Look out for future roundups of play revivals and special engagements. Click here for a look at this season's musicals.Continued...


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County Distribution
Prosopis strombulifera (Lam.) Benth. -
Argentine screwbean
in the state of California
Click the map above to view a larger image.
Our county data are based primarily on the literature, herbarium specimens, and confirmed
observations. However, not all populations have been documented, so some gaps in the
distribution shown above may not be real. Remember that only native and
naturalized populations are mapped!


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New: Bookstore
site map
st. mary's home
Cooperative Programs of Preparation for Ministry
The Ecumenical Institute of Theology has a long history of cooperation with the churches and denominations of greater Baltimore. Formal relationships have been established with the Roman Catholic Archdiocese of Baltimore and the Episcopal Diocese of Maryland to prepare persons for lay ministry. Similar arrangements with other churches are being explored.
Participants in these programs pursue several special courses in conjunction with the regular curriculum for their chosen track, as well as a special program of spiritual and/or ministerial formation within their denomination, in fulfillment of the degree requirements for spiritual formation and growth.
Roman Catholic students may choose to affiliate with the Archdiocese of Baltimore's Division of Ministry Formation and Development, which works with current and prospective lay ecclesial ministers. Interested students should contact the Division of Ministry Formation and Development at 410/547-5470 for questions regarding academic formation or tuition assistance. Students interested in religious education may also wish to contact the Division of Evangelization and Catechesis at 410/547-5406. Students interested in youth ministry may also wish to contact the Division of Youth and Young Adult Ministry at 410/547-5372.
Students affiliated with the Archdiocese of Baltimore's Division of Ministry Formation and Development work with that division to fulfill the spiritual growth and mentoring requirements of the Ecumenical Institute's M.A. in Church Ministries program. These students are also required to take the following courses:
In addition, PT/ST761 Roman Catholic Sacramental Theology and Canon Law for Pastoral Ministers is a required course for candidates in the Congregational Leadership, Pastoral Care, and Religious Education tracks, and is recommended for candidates in the Youth Ministry track.
The Episcopal Diocese of Maryland has an Office of Ministry Discernment Programs to assist students in the process of discerning a call to lay or ordained ministry. Interested students should contact the Office of Ministry Discernment Programs at 410/467-1399 or 800/443-1399. Students interested in Christian education or youth ministry should also contact diocesan missioners in those areas at the same numbers.
Students considering or preparing for ministry in the Diocese of Maryland are strongly urged to take the following courses:


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Commuters to be hit by London rail line closure
There will be upgrade work on a network rail line, which will cause disruption to commuters travelling between London and the North.
There will be no direct services on the West Coast Main Line from Euston to Milton Keynes, Manchester, Liverpool and Glasgow on December 23 and 24, thanks to upgrade work in Bletchley in Milton Keynes. Network Rail has advised passengers to add extra time to their journeys because they will need to use other lines to complete their journeys.
The line reopens and returns to normal Xmas service on December 27 but only two of the usual four lines on the West Coast Main line will be working up to and including New Year's Eve.
Network Rail has told us that the disruption to other lines over the Christmas period has not be been confirmed yet. It said all line closures will be confirmed sometime in early October, after discussions between themselves and train companies.
Network Rail, which is in charge of the national network, says it is carrying out maintenance work at Christmas because there are fewer commuters then and disruption will be minimal.
They estimate that the work on the West Coast Main Line will take no longer than four or five days.
– Robin Gisby, managing director of network operations, Network Rail
Services on the West Coast on 23 and 24 December will be severely affected by a major project to boost capacity and increase line speeds in the Milton Keynes area.
We understand and regret the impact this will have on passengers and freight services, but believe it is unfortunately necessary to achieve the long-term benefits this work will deliver for many years to come.


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Long Beach State's annual fundraising gala, Jewels of the Night, will celebrate its 20th anniversary this year. Jewels of the Night is the marquee event for generating revenue to support the more than 300 Long Beach State student-athletes in their quest to realize both their academic and athletic ambitions.
Students! Take this chance to work with the Athletic Department for the 2014-15 season! Work-Study positions are now open. Please contact Leah Williams-Daniels at (562) 985-5722 or firstname.lastname@example.com.
Can't make the game? Don't want to miss the team on the road? Listen to 49ers action from your home computer by logging on to longbeachstate.com
Long Beach State offers 19 Division I sports on California's second-largest campus. Located in one of Southern California's best coastal cities, LBSU brings marquee facilities, coaches and administration to exceed the needs of more than 300 student-athletes.
Click here
With one of just three Pyramids in the United States, a baseball stadium that has been home to MLB greats such as Troy Tulowitzki, Evan Longoria and Jered Weaver and a marquee tennis complex, Long Beach State Athletics offers some of the finest competitive facilities in California.
Click here
Cathedral Catholic High School: A three-year letterwinner at Cathedral Catholic High School ... A first-team All-North Country Selection ... Also earned a varsity letter in volleyball ... Named the MVP of the AFC Tournament in Coronado, Calif. in 2012 ... Played club water polo with Del Mar.
Major: Undeclared


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A nationwide shortage of prescription drugs is growing and Quincy's Blessing Hospital is feeling the effects of it.
In a statement released Friday morning, Blessing Hospital representatives say in late October the Food & Drug Administration shut down a second major national drug compounding company that supplies medications to thousands of hospitals across the country.
The latest nation-wide shortage list has a 261 medications on it.
Officials at Blessing and other Tri-State hospitals say despite the drug shortage, they're still prepared for an emergency.
Workers at Blessing Hospital's pharmacy are responsibly for providing medication to patients.
But, more than ever before. Blessing pharmacists are spending time behind this glass window making drugs that used to be shipped in.
"We are feeling a little bit of the impact here, a little bit more every day but we wanted everyone to be assured that we are taking steps to address it," said Loyd.
David Loyd is Blessing's administrative director for ancillary services.
Loyd says in addition to compounding their own medication, the hospital is also substituting drugs and getting medication from other providers.
"It's simply man hours, man hours, more work, more frontline hours, and probably a little bit of cost," said Loyd.
It's more of the same at Hannibal Regional Hospital.
Director of Pharmacy Kirsten Myers says they've been feeling the impact of the shortage for 3 years.
"One of the medications we've had the most issues with is, and this is something that's been in the news recently as well is Propofol, it's a medication used for sedation," said Myers.
Myers says Hannibal Regional is using the same techniques as Blessing to make sure medication stays in stock, but says he doesn't see the shortage getting better anytime soon.
"We've not really seen the light at the end of the tunnel so to speak and we will continue to continue our excellent patient care regardless of what happens with the shortages," said Myers.
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1Sharon Stone Used to Cry About Getting Old
Damn, Hollywood is hard on the ladies. It's often the case that women over 40 can't find roles and are expected to keep getting more and more plastic surgery to try and look like their younger counterparts… unless, of course, you're Meryl Streep, but there's only one Meryl Streep. Oh, and Robin Wright is doing her thing, too. There are a few others, of course, but they're very few and far between, and frankly, Sharon Stone couldn't take the pressure.
You see, Sharon is 56 now and seems to have come to terms with aging gracefully, but there was a long stretch of time where she used to lock herself away and cry about the fact that she wasn't a spring chicken anymore. As she told Shape magazine:
"It hasn't been easy. There was a point in my 40s where I went into the bathroom with a bottle of wine, locked the door, and said, 'I'm not coming out until I can totally accept the way I look right now'. I examined my face in the magnifying mirror, and I looked at my body, and I cried and cried and cried."
"I said to myself, 'You're going to get old now. How do you want to do that?' And I thought, 'I'd like to age like a dancer.' I want to keep my body in shape like that. I want to do the work. I like to dance and stretch. And I like going to the gym."
Good for her. I think Sharon Stone looks great and we all need to get over the getting older bullshit. It's great! It just means you have more LIFE behind you, and frankly, that's a good thing, I think.
February 20, 2014 at 1:30 pm by Jennifer
One Response to "Sharon Stone Used to Cry About Getting Old"
Ms. Stone has always been an incredibly sexy woman. I believe it's not just because she looks beautiful, she knows how to project a sensuality that reaches a tantric level… Wow!


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Police name driver killed in M3 crash near Winchester (From Hampshire Chronicle)
When news happens, text CHRON and your photos or videos to 80360. Or contact us by email & phone.
Winchester RSS Feed
Police name driver killed in M3 crash near Winchester
5:08pm Monday 17th December 2012 in Winchester
POLICE have this afternoon named the driver who died in a collision on the M3 near Winchester on Saturday evening.
He was Andrew John Greest, 54, of Pelham Road, Gosport.
Mr Greest died after his Vauxhall was in collision with a second Vauxhall on the southbound carriageway at the Winchester services around 10.13pm.
The other driver, a 44-year-old man from Bournemouth, was arrested on suspicion of causing death by dangerous driving and bailed until February 28.
Police are continuing their investigation and would like to hear from anyone who witnessed it or either vehicle prior to it.
Anyone with information is asked to contact the Road Death Investigation team at Eastleigh, quoting Operation Cardamom, on 101 or the anonymous Crimestoppers charity on 0800 555 111.
Comments are closed on this article.


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Braves begin final road trip of 2008
Atlanta (69-87) at Philadelphia (88-68), Monday, 7:05 p.m. ET
ATLANTA -- Given that there was actually a time when Chipper Jones was worrying about the possibility of a 100-loss season, the Braves probably shouldn't fret too much about the possibility of encountering their first 90-loss season since 1990.In going 10-9 thus far this month, the Braves have at least put themselves in position to end a forgettable season in respectable fashion. But in order to avoid 90 losses, they'll have to win four of their remaining six games on the road and put an end to their season-long miseries against Philadelphia. The Braves will begin their final road trip of the season on Monday with the opener of a three-game series against the Phillies, a team they've beaten just twice in 15 opportunities this year. On a positive note, both of those victories came at Citizens Bank Park. "It would be nice to go up there and get some revenge [against the Phillies]," Jeff Francoeur said. "I know the Mets probably think we're working on a conspiracy against them." The Braves have some momentum entering the series, having won two of three this past weekend against the Mets, who won just one of nine games at Turner Field this year. As for the Phillies, they won each of the nine games they played in Atlanta this year and have been victorious in 13 of the 15 games played against the Braves. "You can't explain why the balls fall in against the Mets and not against the Phillies," Jones said. "Sometimes you have to think it's just fate." Entering the series, the Phillies find themselves in a tight battle with the Mets for the National League East title. But if the playoffs were to begin today, both teams would qualify, with the Phillies winning the division. As the Braves attempt to reverse their season-long trend against the Phillies, there's a chance they'll have the services of Jones, who was out of the starting lineup the past two games with a sore right shoulder. The veteran third baseman drew an intentional walk while batting left-handed during a pinch-hit appearance on Sunday. With his shoulder providing him more problems while swinging from the right side of the plate, the switch-hitter will have to make a decision when the Phillies start left-handers J.A. Happ and Cole Hamels during the first two games of this week's series. With a Major League-leading .362 batting average, Jones doesn't necessarily want to earn his first career batting title while being sidelined during the season's final week. Albert Pujols, who has just two hits in his past 21 at-bats, ranks second in the NL, with a .349 average. "I want to be out there playing," Jones said, "but I'm not healthy. I can't do what I'm supposed to be doing on the field right now." Pitching matchup
ATL: RHP Jair Jurrjens (13-10, 3.72 ERA)
Jurrjens surrendered four runs during a 43-pitch first inning against the Phillies on Wednesday, then held them scoreless while needing just 57 pitches to complete his final four framess. The early damage prevented the 22-year-old rookie from winning his third straight start and equal the success he had at Citizens Bank Park on July 25, when allowed three hits in eight scoreless innings against the Phillies. Facing the same lineup for the second time in five days, he will look to be more aggressive in the strike zone and fight the temptation of showing too much respect to specific hitters. PHI: LHP J.A. Happ (1-0, 4.24 ERA)
Happ will make his second start against Atlanta in five days. The rookie dazzled the Braves with six shutout innings on Wednesday, allowing just three hits, and has a 2.12 ERA in his three starts this season. Manager Charlie Manuel would love an encore. Tidbits
Jones hit .399 at Turner Field this season, establishing the highest home batting average in Atlanta Braves history. Dion James had held the record, with the .376 mark he produced in 1987. ... Jurrjens and Charlie Morton were among the rookies who had to wear dresses and other outrageous costumes during the team's trip to Philadelphia on Sunday night. When he came into the clubhouse and saw some of the outfits, Jones laughed and said, "Man, am I glad I'm not a rookie." ... Kelly Johnson has batted .417 (30-for-72) during his current 19-game hitting streak. It's the longest current streak in the Majors, and it matches the longest in the NL this season. Tickets
Buy tickets now to catch the game in person. On the Internet
Gameday Audio
Official game notes On television
Peachtree Television On radio
WGST 640, 94.9 FM Up next
Tuesday: Braves (Jo-Jo Reyes, 3-11, 5.74) at Phillies (Cole Hamels, 14-9, 3.10), 7:05 p.m. ET
Wednesday: Braves (TBD) at Phillies (Brett Myers, 10-12, 4.46), 7:05 p.m. ET
Thursday: Off-day
Mark Bowman is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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Human Resources Inc
2123 Cartersville Road
Cartersville VA 23027
Phone: (804) 375-3443
Primary Focus: Substance abuse treatment services
Services Provided: Substance abuse treatment
Type of Care: Residential short-term treatment (30 days or less)
Special Programs/Groups: Women, Men
Payment Accepted: Self payment
More Virginia Treatment Centers
If you are in need of immediate medical care, we encourage you to visit your nearest emergency room.
We largely depend on updates from center personnel. If you would like to report a change to the information on this page, please fill out this form.


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Huxley Associates
Huxley Associates Jobs & Careers in Singapore
Network Engineer - Nexus And WAAS
Huxley Associates – Singapore
* Network Deployment process and controls. * Have an in-depth understanding of Cisco network technologies including management Expert level subject… Glassdoor
Corporate Banking Core Banking PM
Huxley Associates – Singapore
- Have extensive experience working in corporate banking - Change management and project management experience - Excellent stakeholder management… Glassdoor
Wealth Management Compliance Officer
Huxley Associates – Singapore
* Check account opening application to ensure compliance to Bank's policy * Escalate unresolved account opening issues to Compliance * Review… Glassdoor
Insurance Manager
Huxley Associates – Singapore
- Be responsible for a team of bankers, managing and guiding them to achieve revenue targets. - Join client discussions to provide a customized… Glassdoor
Senior Client Advisor
Huxley Associates – Singapore
* Existing Relationship Managers are strongly encouraged to apply. * CMFAS Qualification papers Candidates can expect good exposure to a world… Glassdoor
MIS and Regulatory Reporting Specialist
Huxley Associates – Singapore
/ Requirements include: - Regulatory reporting to MAS e.g. MAS Returns and MAS Notices (MAS 610, 613, 630) - Analyse, report and provide commentary… Glassdoor
Credit Manager - Commodities
Huxley Associates – Singapore
- Perform credit analysis; recommend credit limits and terms for counterparties - Manage relations with key stake holders like Traders, Front Office… Glassdoor
Vice President - Affinity (Leading Insurance MNC)
Huxley Associates – Singapore
You will be provided access to an extensive range of valuable resources, as well as work alongside an experienced team. Learning and development… Glassdoor
Operational Risk & Control Manager
Huxley Associates – Singapore
- Develop Internal Control Monitoring processes - Prepare Risk & Control related management reports - Develop and manage testing plans for Business… Glassdoor
Quant Analyst, Portfolio Strategy, Buy Side
Huxley Associates – Singapore
Vacancy: One of the leading buy side institutions here in Singapore is looking for a Quant to join their Investment Solution Team who are responsible… Glassdoor
Updated Sep 02, 2014
See What Huxley Associates Employees Are Saying
Employees are "Satisfied" 41 ratings
75% of the CEO 5 ratings
Mike Smith
Managing Director
Pros: "You get great rewards for being successful. Trips abroad, good commission scheme and career opportunities. There is a good atmosphere and it can be a fun place to work. Recognition form management if you perform." – Full Review
If you're searching for Huxley Associates jobs and careers — we can help! Here you'll not only find the latest Huxley Associates job openings, you can also see what Huxley Associates employees have to say about a career at Huxley Associates – salaries, reviews, and interview questions all posted anonymously by Huxley Associates employees and job seekers.


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Sometimes in life, and especially in the world of sports, it's easy to focus on the negative.
And why do we do that?
Probably because it's often hilarious and revenue-increasing to drop a funny acronym, make a montage video of a blown save or poke fun at a team or player's shortcomings, instead of focusing on the good aspects.
Positivity doesn't sell advertising.
When I think of why I became a Sens fan, it wasn't for glory, it wasn't for status and it sure as hell didn't have to do with hitching a cart to a winning team.
Growing up as a massive fan of Mike Modano, I was a Stars fan, through and through. I first started cheering for the Stars in 1991 when they were still in Minnesota, and when they went to the Cup and got torn apart by Lemieux and the Penguins.
The main reason why I chose them as my hockey team? My brother had a felt green Stars hat (that I basically stole) and it fit well on my massive head. I also liked the fact that it was a different choice. I didn't know anyone else in Ottawa, or in my teenage life, who cheered for them.
Later on, when Ottawa got a team, I got to see the Dallas version of the Stars play in Ottawa. I remember watching Mike Modano and Russ Courtnall move the puck around like they were wizards and it was an object under their spell – and I was hooked.
But all of that changed when my good, family friend Laurie Boschman (the first captain of the new Ottawa Senators club) came into my life. Working on the same floor as my dad, I had an inside track and I would pick Laurie's brain about Modano and all of my other favourite players and I was entranced by the response and findings of a man who had actually shared playing time and even ice with those heroes of mine.
But in listening to Bosch talk about all of those players, a funny thing happened. I began to care less about the Stars and more about the Senators. I remember the bad years. The really bad years. And I remember the upward swing. And I remember Chara and a close call against Anaheim. And I remember last year – when a team that was plagued with injuries made it to the second round of the playoffs (further than any other Canadian team, I might add).
Yeah, Dallas went on to win a few times. But by then, I didn't care. I understood that this team in my hometown was my team, now.
Yes – the Sens lost to the Leafs in a shootout, and even blew a 4-2 lead. But this is a team that needs to score – and they did that. Kyle Turris, the 2nd line playmaker, even got 3 points (even though a lot of hockey fans still have no idea who he is.)
Spezza even jumped into the point wave with a decent blast, getting his first goal of the season, and it seems that the riddle of Reimer is finally solved for the Sens.
Anderson looked human, but that's what happens when your team only gets one power play and the other team gets five.
The game before that, Craig Anderson notched an impressive shutout against a hungry Buffalo team.
They have put 83 shots on goal in two games.
So they are 1-0-1. So what?
All of the headlines I have read about the Sens lately have to do with Mason Raymond's spinorama shootout goal, and how controversial it was. Who cares?
If I had my way, shootouts wouldn't even be in the NHL. Putting a fast player on the ice to try and deke out a goalie, in a one-on-one scenario, doesn't properly reflect hockey. At all. Why does it need to be the deciding factor for a game?
Why do regular season hockey and playoff hockey have to be so different? Does it have to be this way? Can't there just be endless overtimes?
Philosophical questions aside, it's important to see the positives, here.
The Sens have a strong team, and no – they aren't going to miss Alfredsson as much as everyone says they are.
The shortened season provided its own scheduling challenges, but with a normal season at hand, building on the good shouldn't be a problem.
Heading into Los Angeles on Wednesday, I'll be cheering for my team and remembering just how far they've come since 1992.


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Last spring, in the aftermath of revelations that the Obama administration was actively intimidating members of the Associated Press and FOX News, Senators Chuck Schumer (D-NY) and Lindsey Graham (R-SC) worked together on legislation that was meant to "protect" members of the media from government interference and harassment when doing their jobs. Unfortunately, as is usually the case in Washington, this legislation created an indirect and highly undesirable side effect. As we documented in our piece, Joseph Goebbels would love Lindsey Graham, Senator Graham was having a great deal of trouble figuring out exactly who should receive this protection: "Who is a journalist is a question we need to ask…
- Constitution
- Energy
- Healthcare
- Politics
- Religion
- G.O.P. Hall Of Shame
- Conservative Comedy


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A crash on US Route 40 in Perryville occurred around the same time the area experienced a power outage.
Delmarva Power stated on its outage map that the cause of the power outage, which left nearly 400 people without power in Cecil County, was under investigation.
Areas affected included Perryville, Port Deposit and points north.
The outage was reported at 5:58 p.m. Monday with a restoration time between 9 and 11 p.m. projected.
A crash was reported at approximately 6 p.m. at Belvedere Road near Route 40, according to WXCY Traffic.
Maryland State Police told Patch at approximately 7:15 p.m. Monday that there was no information available about the crash.


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Team Vet Med's First Game by CoachChris - almost 8 years ago
"This was taken at the first at the University of Florida College of Veterinary Medicine's first softball game. The wonderful staff at CustomInk help design our jerseys and shirts for our fans. Everyone at CustomInk was very nice and extremely helpful and my order arrived very quickly."


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This is a collection of 15 great stories from some of our favorite sites around the web. Those of us in the industry call it a "link dump." We run two per day. We call the first one "Morning Dump" because it's early and we're immature. We call this one "Morning Dump: Afternoon Edition" because we're lazy and uncreative by noon each day (click the pics to read each article):
1. The 25 Worst Movies on Netflix Watch Instantly (Super Booyah)
2. First Look Anne Hathaway as Catwoman (Nextround)
3. 100 Awesome Pics of Hotties (CavemanCircus)
4. Afternoon Snack (TheDailyWhat)
5. The 8 Most Baffling Food Mascots of All Time (Cracked)
6. Breakdancer Needs Practice (Totallycrap)
7. Daily Babe Gallery (FamousMisfortune)
8. Top 100 Photos of the Week (Izismile)
9. Father and Daughter Relax at the Beach (Unrealitymag)
10. Rollercoaster Videos Timed to Perfection (CoedMagazine)
11. The 25 Most Iconic Hip Hop Cars (Complex)
12. MVP Trains with Tanahashi in Japan (HeymanHustle)
13. A Gallery of Sad Wall Street Traders (EgoTV)
14. How to Drink Tropically (Esquire)
15. 6 Strangest and Often Unnecessary Examples of CGI in Sci-Fi Films (Blastr)


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Ferguson's streets remained peaceful as tensions between police and protesters continued to subside after nights of violence and unrest that erupted when a white police officer fatally shot an unarmed black 18-year-old. More>>
Residents of a neighborhood where an Oklahoma City officer is accused of sexually assaulting women say the allegations make them distrust police. More>>
Thousands of people expressing grief, anger and hope for a better future marched through Staten Island on Saturday to protest the chokehold death of an unarmed black man by a white police officer. More>>
As one of few Ebola survivors with medical expertise, Dr. Kent Brantly seems keenly aware of the position his painful experience has put him in. He hasn't spoken yet about his plans, but spent much of his first public... More>>
An Oklahoma oral surgeon whose filthy clinic conditions led to the testing of thousands of patients for HIV and hepatitis permanently surrendered his professional license on Friday. More>>
Life in this working-class St. Louis suburb of modest brick homes and low-rise apartments hasn't been the same since Angelia Dickens' son tearfully told her, "The police shot a boy." More>>
The parents of slain journalist James Foley said they regarded an email they received from his captors last week as a hopeful sign they could negotiate with the Islamic militants. More>>
Gay bathhouses that once remained in the shadows to stay in business are now seeking attention to keep their doors open. More>>
About 63 trillion gallons of water have been lost to drought in the western United States, enough to blanket the region with 4 inches of water, according to a study published Thursday. More>>
New research suggests a one-two punch could help battle polio in some of the world's most remote and strife-torn regions: Giving a single vaccine shot to children who've already swallowed drops of an oral polio... More>>
An estimated 10 homes were damaged or destroyed and highways were blocked as heavy rains unleashed mudslides in an area of north-central Washington where hillsides have been left barren by wildfires. More>>
A Wyoming police officer has pleaded not guilty to an animal-cruelty charge that alleges a police dog died after he left it in a hot patrol car for several hours. More>>
Heavy rains that unleashed mud slides in an area of north-central Washington where hillsides have been left barren by wildfires damaged or destroyed an estimated 10 homes and blocked highways, officials said Friday. More>>
Conditions calmed this week in Ferguson after nights of sometimes violent unrest stemming from the fatal shooting of a black 18-year-old by a white police officer. But a delicate and crucial question lingers: What happens... More>>
A California woman is under investigation after trying to enter a hospital maternity ward carrying a doll that looked like a living baby, police said Friday, but the woman says the dolls are meant to be therapeutic for... More>>
A judge ordered a Denver man on Friday to stand trial in the killing of his wife, who told dispatchers moments before her death that he was paranoid and hallucinating after eating marijuana-infused candy. More>>
Lawyers for Dzhokhar Tsarnaev asked a judge on Friday to dismiss indictments against the Boston Marathon bombing suspect and put on hold further proceedings in the case over concerns about the process of selecting jurors... More>>
John Lennon's killer was denied release from prison in his eighth appearance before a parole board, correction officials said Friday. More>>
The Pierce County medical examiner has identified the bodies of three climbers recovered this week from Mount Rainier. They were part of a party of six who vanished on the Washington state peak last May. More>>
By ED WHITE Associated Press A grand jury is considering evidence to determine whether Officer Darren Wilson should be charged in the fatal shooting of Michael Brown in Ferguson, Missouri, on Aug. 9. More>>
Former Virginia Gov. Bob McDonnell told jurors Friday he was both innocent and contrite as he ended his third straight day of testifying in his corruption trial. More>>
A woman is to be sentenced next month for setting a wildfire on the Warm Springs Indian Reservation in central Oregon because her firefighter friends were bored and needed work. More>>
A coalition of lawyers filed a lawsuit Friday to halt the quick deportation of Central American women and children, saying immigrants at a New Mexico detention center don't have proper access to lawyers and are being... More>>
An Oklahoma City police officer arrested on charges of serial sexual assault preyed on women in the rundown neighborhoods he was assigned to patrol - picking some up off the street, pulling others over at traffic stops and... More>>
Two central Kentucky firefighters are still hospitalized a day after they were shocked by a power line while helping out with an "ice bucket challenge." More>>
A top U.S. health official plans to travel to West Africa to see firsthand how the Ebola outbreak is unfolding. More>>
Two American aid workers have recovered from Ebola and left an Atlanta hospital, after weeks of intensive treatment in a special isolation unit. More>>
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text:
Making Ice Castles
Fill small plastic containers (yogurt and drink cups, deli salad tubs) and at least one ice cube tray with water and freeze overnight (outside if it's cold enough).
The next day, set the kids to building — it's like making a sand castle, only colder. (A hot water rinse over the containers will help the ice slip out.) Stack the ice chunks, mixing them up (cubes make great castle-top crenellations). Mist from a spray bottle helps the pieces stick together, or try packing gaps and crevices with snow, if available, for a good seal. Frigid weather will preserve the reign of the kingdom.
For more ice castle ideas, check out St. Paul's ice castles online for inspiration: winter-carnival.com — they've been making them on a grand scale there for more than 100 years.