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Genomic Consequences of Restoring p53 Transactivating Function with PRIMA-1 in Breast Cancer
Scientific Abstract:
Genomic Consequences of Restoring p53 Transactivating Function With PRIMA-1 in Breast Cancer a) Background: Mutations in p53 genes are common in human cancers and more than half of breast tumors harbor mutations in p53 protein. Various cellular stresses such as DNA damage, hypoxia and oncogene activation result in stabilization of p53 that culminates either in apoptosis or cell cycle arrest due to enhanced transcriptional activation of p53 target genes. As tumor cells become more refractory to chemotherapy and radiotherapy, considerable scientific efforts are directed to restore normal function of mutant p53 to promote tumor growth inhibition either by the induction of apoptosis or cell cycle arrest. From such studies, PRIMA-1 (p53-reactivation and induction of massive apoptosis) was identified in an in vitro screen of drugs that enable mutant p53 to restore its sequence specific DNA binding confirmation and transcriptional activity of target genes. We showed that PRIMA-1 restored p53 transcriptional activity of p21 and PUMA (p53-dependent pro-apoptotic gene) in breast cancer cells. Therefore, we propose to use PRIMA-1 as an adjuvant therapy with DNA damaging agent such as adriamycin for the treatment of breast cancer, because it (1) restores p53 transcriptional transactivation function in breast cancer cells, (2) has antitumor activity in its own right (3) is not a substrate (small molecule) for multidrug resistance. In addition, we will identify protein-binding partners of p53 protein (p53 complexes) with tools available for proteomics application. b) Objective/Hypothesis: We propose that the restoration of transcriptional transactivation function of mutant p53 with PRIMA-1 provides an effective adjuvant therapy for breast cancer when used in combination with DNA damaging agents such as adriamycin. This approach allows for the use of lower doses of adriamycin to achieve higher tumor cell killing. Furthermore, we hypothesize that protein-protein interactions critical for p53 function restoration will be identified using tools for proteomics analysis. c) Specific Aims: (1) To test the ability of PRIMA-1 to facilitate apoptosis of breast cancer cells treated in vitro and in a mouse model of breast cancer with adriamycin. In vitro testing will involve the use of normal mammary epithelial cells (HMEC), human MCF-7 breast carcinoma cells (p53 wild-type), human GI101A and MDA-231 breast carcinoma cells (both p53-mutant), and human MDA-157 breast carcinoma cells (p53 null), as we previously reported. The in vivo testing will involve the use of our nude mice model developed for breast cancer. (2) To identify protein-binding partners of p53 with tools available for proteomics analysis. We will use immunoprecipitated p53 complexes obtained from cytoplasmic and nuclear fractions of normal and various breast cancer cells and determine potential binding partners (protein-protein interactions) as well as protein expression profiling by 2D-gel electrophoresis and mass spectrometry. d) Study Design: In specific aim 1, we will test the ability of PRIMA-1 to facilitate apoptosis of adriamycin on breast cancer cells. Mitochondrial involvement as target for p53-produced apoptosis will be investigated. We will also examine the effects of various treatments on normal mammary epithelial cells and select the treatment combination for in vivo experiments that induces maximal apoptosis with minimal toxicity in our mouse model of breast cancer. In specific aim 2, we will identify p53-protein partners following treatment with PRIMA-1 by co-immunoprecipitation and LC/MS/MS-based proteomics analysis. Furthermore, we will characterize protein expression profiling of cytoplasmic and nuclear fractions of normal and tumor cells treated with PRIMA-1 with 2D-gel electrophoresis and Ion exchange chromatography. Our aim is to use various mass spectrometry-based proteomic tools such as MALDI-TOF, quadrupole ion trap, and FTICR-MS with both MALDI and ESI combined with chromatographic separations to maximize our ability to identify functionally relevant proteins for better understanding of p53 function restoration with PRIMA-1. e) Potential Outcomes and Benefits of the Research: The proposed application is designed to selectively target tumor cells by virtue of their defects in p53 signaling. The proposed experiments are important because they should enhance the likelihood that new, less toxic, apoptosis-based therapies will be developed for the treatment of breast cancer in women. Furthermore, we anticipate that our functional proteomics approach will lead to the identification of protein-based, breast cancer-specific targets.
Lay Abstract:
Genomic Consequences of Restoring p53 Transactivating Function With PRIMA-1 in Breast Cancer Sometimes called the "guardian of the genome", the tumor suppressor protein p53 responds to DNA damage by either shutting down cell division or causing cells to commit suicide, a process known as apoptosis. Either way, p53's action helps short-circuit tumor formation by preventing cells that have suffered malignant mutations from continuing to grow. Yet the p53 gene itself is susceptible to damage, which is thought to contribute to the majority of all human cancers including more than 50% of breast cancer. Tumor cells defective in p53 gene tend also to be resistant to the effect of chemo- and radiotherapy. Therefore, considerable research effort has centered on how to restore the normal function to mutant p53 protein to halt cell division and to trigger cell suicide (apoptosis) mechanisms. PRIMA-1 (p53-reactivation and induction of massive apoptosis) emerged from an in vitro screen for drugs that may be able to restore the normal function of some mutated p53 proteins. Recently we showed that PRIMA-1 restored the p53 function in breast cancer cells through transcriptional transactivation of p53-target genes such as p21 and PUMA (p53 up-regulated modulator of apoptosis). Therefore, we propose to use PRIMA-1 as an adjuvant therapy in combination with clinically useful anticancer drugs such as adriamycin for the treatment of breast cancer, because it (a) restores p53 functional activity in breast cancer cells, (b) has anticancer activity in its own right, and (c) is not involved (small molecule) in drug resistance similar to adriamycin. Our preliminary data provided in this application showed the existence of marked synergism between PRIMA-1 and adriamycin on breast cancer cells, especially when adriamycin is given first followed by PRIMA-1. These observations indicate that combined treatment of adriamycin + PRIMA-1 may achieve better therapeutic outcome than the use of each drug individually. In specific aim 1, we will test the ability of PRIMA-1 to facilitate the induction of apoptosis in breast cancer cells with mutant p53 when treated in vitro with adriamycin, a clinically approved drug for the treatment of primary and metastatic breast cancer. Tumor cells mutated for p53 tend to be resistant to this drug. We will examine the ability of the treatment regimen to inhibit growth, induce apoptosis and increase survival of human breast tumors inoculated into immunocomparimised mice that will not reject human breast tumors. If successful, these experiments will provide a valuable model in which to investigate the optimal dose and schedule for drug administration. In turn, this approach will provide critical information for the subsequent application to human clinical trials. In specific aim 2, we will identify partner proteins that tend to interact with p53 as a function of restored confirmation with PRIMA-1. To halt cell division or trigger apoptosis mechanisms, p53 protein needs to regulate the activity of many other proteins (protein-protein interactions) that requires its binding first to the DNA of the target gene regulatory sequences. To identify how precisely PRIMA-1 modulates this protein-protein interactions, we will use an approach called Functional Proteomics. It consists of selective purification and enrichement of a bait protein (p53) and its interactors from cell lysate, protein separation by gel electrophoresis, excision of protein spots and in-gel protein digestion followed by mass spectrometric analysis for protein identification and characterization. We used this approach and successfully identified the heat shock protein-90 (HSP90) as one of p53-partner proteins that highly expressed upon PRIMA-1 treatment. Our further investigation of this type of protein-protein interactions will identify additional proteins that show altered levels of interaction with p53 upon PRIMA-1 treatment. This approach will not only reveal how potential anticancer agents such as PRIMA-1 affect p53-protein interactions, but more importantly, how p53 mutation can modulate p53 function. Thus, our proteomics approach could potentially provide oppotunities for rational drug discovery and individualization of therapy for breast cancer patients through the identification of protein-based, breast cancer-specific targets.
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All right San Francisco the moment is finally here. Disgual brings its "Undie Party" to the bay area. The first 100 people that line up with nothing but their undies on will receive a free 2 piece outfit. Those that aren't the first 100 will still receive 50% OFF. So strip down and maybe we will see you there!
When: March 2nd
Time: Starts at 7am
Where: Disgual 101 Powell st San Francisco, CA

subset: commoncrawl


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Pearl at the Beach in Indian Rocks Beach
- bedrooms 2
- baths 1
- sleeps 4
- pool no
- hot tub no
- pets allowed no
- type House
- community
rates (USD)
/ night
$ 700 - $ 900 / week
$ 1,800 - $ 2,200 / month
Indian Rocks Beach House deals
stays between: 9/12/14 & 10/31/14
deal expires in: 2 days
All-Brand-New Luxury Beach House for $1500 a month
All-Brand-New Luxury Beach house for $1500 a month, all included! September and October - best time in Florida!
- $2,200 $1,500/month ($700 off)
deal# DFUV95
vacation rental description
- Luxury single family home 2 min walk to the Beach!
- The cleanest place on the Beach! Brand new high-end everything!
- Well maintained with love and care, many luxyry items for you to use.
- No steps, no stairs, from your car to your house - all ages welcome!
- Beautiful completely remodeled single family home with tropical landscape!
- One block from the gorgeous white sand beaches of Indian Rocks Beach.
- High-design kitchen with beautiful Delicatus-granite countertops, custom cherry wood cabinets, and new LG stainless steel matching appliances. Icemaker and small appliances included. You will have all you need for gourmet cooking.
- Two bedrooms with new highest quality Beautyrest queen beds and custom closet organizers. Marriott-quality sheets and towels.
- Each bedroom has brand new 32" LED wall-mounted TVs with Cable and High Speed Internet included. The fastest Internet in the area!
- Living room has new designer leather furniture (full size sofa and love seat) and a new 50" flat screen TV with Bright House recorder for your 2000 channels.
- Bathroom has Italian marble and a European shower with modern Ikea cabinets.
- New 21" Capuccino-porcelain tile flooring throughout.
- All brand new Air Conditioning/Heating including new air ducts, alergy-proof air.
- Tennis courts and baseball park just steps away.
- Full size washer/dryer and outdoor shower.
- Large patio/yard with beautiful custom pavers and lovely tropical landscaping—a wonderful place to barbeque and have cocktails! Patio furniture and grill are also included.
- Beach chairs, beach towels, umbrellas, coolers and launch chairs are included.
- This home is located in a prime area of Indian Rocks beach, close to restaurant Guppy's.
- Parking is ample and there is room to park your boat in one of the two driveways. Launch your kayaks and boats at our boat ramp just two blocks from the house!
- Fisthing just steps away in Gulf of Mexico or Intercoastal water way.
- You may not need a car here! You can walk to the beach and area restaurants! You can take the beach trolley to explore other beaches (Clearwater Beach, Sand Key, Indian Shores, Redington Beach, Madeira Beach, Treasure Island, St. Pete Beach, Pass-a-Grille, Honeymoon Island, Tarpon Springs, and more!)
vacation rental location
property availability
- dates with deals
- unavailable dates
Last modified on 08-5-2013 at 10:41 AM.
email owner view full calendar
Inessa (727)631-4363
house rental amenities
- Beach - two min walk from the house.
- High speed Internet and WiFi.
- Cable TV with Upgraded Cable
- Three flat screen TVs
- Outdoor patio 2800 sq ft paved with furniture and grill
- Laundry room with full size washer/dryer
- Outdoor shower
- Immaculate landscaping with rose garden and palm trees
- Tennis courts and baseball park across the street
- Boat ramp two blocks away
- Specal rates off-seaosn
- Free parking for 4 cars.
activities and attractions in Indian Rocks Beach Gulf Coast Central
Walking distance to the Beach, kayak, paddle board and bicycle rentals one block from the house. Walking distance many restaurants - fine dining and beach restaurants and bars all are here: Food Network Celebrity - Keegan's seafood, Guppy's at the Beach, Cuso's, The Red Lion, JD"s at the Beach, Villa Galace, Cafe De Paris, BJ's Pizza and Italian Restaurant, Salt Rock Grill, The Pub waterfrond dining, Crabby Bills, PJ's Oyster Bar, Jimmy Guana's at Holiday Inn, Los Mexicanos, Maco's night club, Bonefish, Marlin Darlin, Panera Bread, Starbucks Coffee and many more!!!
Just a short drive North to Clearwater Beach or South to John's Pass Village, where you can enjoy shopping, dining, boat and jet ski rentals, fishing, gambling or dinner cruises.
Bush Gardens - 45 min, Orlando / Disney World - 1.5h, Lawry Park Zoo 45 min. Sports: Rays, Buccaneers, Tampa Bay Lightning - 30 min from the property, outlet mall 1.5h.
vacation rental rates
$1500 for the month of September and/or October
Inessa (727)631-4363
accepted payment methods
Prior to paying a reservation deposit, always verify payment instructions by calling the phone number displayed on this listing page. By contacting the owner directly and paying by an approved method - credit card, paypal, check or bank transfer - your reservation payment will be protected up to $1,000.Learn more in our Security Center
Top things to do in Indian Rocks Beach
- Walk White Sand Beaches
- Dining - over 20 restaurants
- Music, dancing, happy hour
- Kayaking, paddleboarding, bicycling
- Scootering, boating
Top things to do on a budget
- Walk the Beach, swim, bike
- Happy hour with music
- Early bird dinners in top-rated restaurants
- Sunsets, bird watching, barbeque
- Take a Trolley - save on car rental expence
Top things to do with a family
- Beach, all beach toys included
- Dining, top restaurants and bars in walking distance
- Bush Gardens, Lawry park Zoo
- Bicycling, mini-golf, scootering, fishing
- Kayaking, boating, paddle-boarding
Inessa , owner


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Here's an approach. Maybe not the best approach, but it could be like plan 5c or something.
If Alex Len falls to the ten, then you invest in the future. You grab the aforementioned at the ten and acquire another pick between 12-20 somewhere and grab Steven Adams or whomever the paul allen team deem BAC, there will be a bunch in that area.
2013-2014 will be pretty painful to watch. It's true. But hurrah for the draft and the crazy FA field. Now you got 3 possibly promising young centers. One of them is clearly the best for our system. You keep him. Number 2 is trade bait for picks in that wonderful lottery coming up next year and number 3 is your backup.
Center Problem solved. Center of the future acquired.
Hello 2014-2015!


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Today is the final day of Devo180 for 2012-2013. While other new content will be appearing on Wherethewind.com, Devo180 will be on hiatus for the summer. So it's appropriate that we end our season on a high note — with a psalm of praise. Continue reading
Tag Archives: Psalms
Sacrifice of Thanksgiving (May 27, 2013)
We begin the final week of the third season of Devo180 with our the tenth out of fourteen devotions based on verses on my old guitar case. Today, we're talking about what it means to make a sacrifice of thanksgiving. Continue reading
Into Your Hands (May 24, 2013)
Another verse from the Psalms — that book is really greater, btw. I've been reading through the whole thing over the last few weeks and everyday a verse or two just strikes me. This one always has. Continue reading
Clothed me with Joy (May 22, 2013)
My favorite verse from the Psalms makes an appearance today. The ladies at church laugh because I say verses are my favorite all the time, but I really mean it this time. Continue reading
I Will Praise (May 16, 2013)
The third quotation on my guitar case is written vertically down the neck. It comes from a psalm of lament, but itself is a verse of praise. How could these two things go together? Continue reading
Teach Me Discernment (May 15, 2013)
The next quote is underneath the first and flipped upside down on the guitar case. The psalmist prays that God "teach discernment." What does that mean? Continue reading
My Old Guitar Case (May 13, 2013)
This week on Devo180, we begin a look at a series of Bible verses that have meant something to me for quite some time. They are enshrined on my old guitar case, and we'll be looking at them over the next few weeks. Continue reading
The Fireplace's Crackle (May 9, 2013)
Our third lesson from childhood on devo180: wonder. Continue reading
You Care About Me Lord (May 3, 2013)
…Opening To… Come, then, Lord my God, come and instruct my heart where and how to search for you, where and how to find you. Where shall I look for you, Lord? (St. Anselm) …Listening In… Lord, you have examined me. You know me. You know when I sit down and when I stand up. … Continue reading
Turning off the Autopilot (April 25, 2013)
…Opening To… For life, with all it yields of joy and woe And hope and fear,—believe the aged friend,— Is just our chance o' the prize of learning love. (Robert Browning, "A Death in the Desert") …Listening In… And yes, you want truth in the most hidden places; you teach me wisdom in the most … Continue reading


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Changes related to "How to detect if a Class/Package is available on the phone"
This is a list of changes made recently to pages linked from a specified page (or to members of a specified category). Pages on your watchlist are bold.
No changes on linked pages during the given period.


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{Ed. note: FP'd (I'm on vacation this week so content from me is going to be pretty limited, I apologize. It's not like there's a ton going on anyway)}
Just from watching the DraftExpress video, it seems like he will fit in well with the fast-pasted offense that Byron is trying to implement.
Tyler Zeller 2012 NBA Draft Video (via TheMikeSchmitz)
I think we are really going to end up agreeing with Scott/Grant that he should have been taken in the top 10 of this very talented draft class.
He seems to be much more of a 'known' than Dion, at least at this point in the summer where we are still sort of left with a bad taste in our mouth from Summer League.


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Billion Officially Launches Embedded Dual-SIM Mobile Broadband Router - BiPAC 7820NZ, Offering Reliable Network Connectivity for Industrial Applications
February 18th, 2014 – Taipei, Taiwan – Billion Electric Co., Ltd. (Taiex: 3027, trading as Billion), a leading supplier in network communication and energy management solutions officially launches a new cutting-edge dual-SIM 3G/4G LTE mobile broadband router – BiPAC 7820NZ. Its uniquely embedded dual-SIM card slot enables users to enjoy constant and seamless Internet experience by simply plugging 3G/4G LTE SIM cards into its built-in SIM slots without the needs of additional 3G/4G LTE USB modems. It is perfectly suitable for machine-to-machine (M2M) applications in industries ranging from automotive, agriculture, construction, healthcare, logistics, retail services, public safety, and transportation.
"Foreseeing the vigorous development of
Press Information:Billion Electric CO, Ltd.8F., No.192, Sec. 2, Zhongxing Rd., Xindian Dist., New Taipei City 231, Taiwan (R.O.C.)Contact Person:Alice LiuMarketing SpecialistPhone: +886-1-2914-5665email: emailWeb: www.billion.com.tw


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CUCKOO is creating
Music and Animation
I'd like to give you ALL of my music!
Milestone Goals
Studio Rent
My studio is costing me exactly $325 a month. I love this place, and without it I wouldn't be able to do these things. It'd be such a great feeling if I could finance the studio by making and sharing music and videos.
Wirecast Studio
Wirecast Studio is a streaming software for YouTube. The free version is all right, but with the studio version I can make more rich live streams. It's on my list :) (it's not precisely a "per video" goal, but more of a one time goal.
Making music and animation takes love and passion… but also a great deal of time. And with time comes studio rent, food, family etc… When I reach $2.500 per video I've reached the point where I can quit other jobs and focus on music and art, and on sharing it all with you, and still pay rent and food. This is a grand goal.. but in time, and with your help, and if I make increasingly great things, I think it's possible.
I love to share all I know about synthesisers and animation. I'm constantly making new music in my own little studio. I'm testing and reviewing new synths, giving hints and inspiration on how to use your synths, or just play songs for you. I'm also preparing for streaming youtube concerts live. With your continuos support I can dedicate more time to the arts and performing for you. Every contribution is helping me stay independent and focused.
I'm really so incredibly thankful for all of your comments and cheering me up. Without you my life would be quite heavy.
Big thanks and cheers
Top PatronsSee all 52
Hello!Thanks for checking in.
I'd love to share all my music and videos with you. Is that ok?
If you'd care to donate a few bucks for every new video that I make you will actively help me create more, and higher quality videos about synths and music. And that's what I want to do. Connecting to people around the world really helps me keep making and sharing more videos.
The spirit of freeI intend to keep all my YouTube videos free of commercials. It's important to me. If you'd like to see more videos and music from me, I'm hoping that you'd consider donating a few bucks every time I make a new video, and helping me in my independent work. With your help I can make it all better and more interesting. Every little donation counts, so don't be shy to sign up for just $1 if you'd like to.
I'm looking forward to evolving here on Patreon, together with you, if you want to :)
Now enjoy my latest CUCKOO remix.
Wrecking Ball - CUCKOO REMIX
best regards


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American League
Brett Gardner, OF, NY Yankees – 15-Day DL with a sore right elbow. The Holly Hill native suffered a setback in his rehab and will reportedly miss another 2-4 weeks
Matt Wieters, C, Baltimore Orioles – 0-2 with a walk, a run scored and 2 K's in a 6-5 win over the Rangers. The Stratford alum is now batting .294. He didn't play in game 2 of the doubleheader
Justin Smoak, 1B, Seattle Mariners – No game
International League
Justin Greene, OF, Charlotte (Chicago White Sox) - The Stratford alum was called up to Triple-A early Thursday morning. He went 1-4 with a double in a 2-0 loss to Toledo. He extended his personal hitting streak to 11 games
Eastern League
Mike Cisco, P, Reading (Philadelphia Phillies) – Pitched 2 innings giving up 2 hits, 1 run along with 1 walk and 2 K's in a 10-3 win over New Britain. The Wando alum's ERA is up to 1.42
Reese Havens, 2B, Binghamton (NY Mets) – 1-4 with a double (2), a walk, 2 RBI (5), a run scored and 2 K's in a 9-2 win over New Hampshire. The Bishop England alum is batting .206
John Murrian, C, Erie (Detroit Tigers) – Did not play in an 8-4 win over Altoona
Texas League
Chris McGuiness, 1B, Frisco (Texas Rangers) – 1-3 with 2 walks and an RBI (18) in a 10-2 win over Corpus Christi. The James Island native is batting .243
Bryan Altman, IF, San Antonio (San Diego Padres) – Game vs. Midland PPD
Florida State League
Asher Wojciechowski, P, Dunedin (Toronto Blue Jays) – Pitched 2.1 innings giving up 8 runs on 9 hits to go with 3 K's in a 12-11 loss to Ft. Myers. The Beaufort alum took the loss (1-1) and his ERA is up to 5.40
Midwest League
Drew Cisco, P, Dayton (Cincinnati Reds) – Did not pitch in a 2-1 loss to Lake County
South Atlantic League
John Cornely, Rome (Atlanta Braves) – Pitched 1/3 of an inning giving up 2 hits, 2 runs and a walk in a 2-0 loss to Asheville. The Bishop England alum took the loss (0-2) and his ERA is up to 4.97
Chris Hanna, Hickory (Texas Rangers) – Did not pitch in a 7-2 loss to Savannah
2126 Charlie Hall Boulevard
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As the offseason really begins to get going in the coming days and weeks, I started to think about how this team really can best address the needs that they have. As I thought about it, I came to two realizations.
A)This team does not have as many positions needing addressing as I originally thought:
- While I originally though it, I realized that OG does not really need addressing. On the roster right now are young guys like Will Rackley, Drew Nowak, Austin Pasztor, and even Mark Asper. This team needs a starting LG, and with Rackley having been hurt last year, and Nowak getting hurt early into his seemingly impressive start as an OG, I am not really sure that Caldwell/Bradley should discount the possibility that one of those two guys can be a good LG in the NFL. My money would be on Rackley, and given the supposed emphasis on zone-blocking in the new scheme, I really think that it is possible Rackley could run away with the job in an open competition. As for depth, those remaining guys really are not bad depth for OG. Pasztor was pretty good in his limited playing time last year, and as previously mentioned, Nowak was seemingly impressive following his switch to OG last year.
- While the position does need to be addressed, I would not say it is absolutely imperative to bring in a QB in FA or through the earlier rounds in the draft. That is not to say that the team won't, but I really feel like it is not absolutely needed. As it stands, Gabbert is going to get one more year to show his ability as a starting QB in the NFL. Obviously, competition would be really nice, and spending an early round pick on a QB or getting a guy like A. Smith or M. Flynn could be really great for an open competition, but in truth, is it really necessary? I think it is safe to say that if Gabbert bombs, this team goes to the 2014 NFL Draft and takes one of the numerous excellent QB prospects likely to be in the draft. I am not sure that an open competition and a guy like Alex Smith or Matt Flynn will actually make Gabbert any better; after all, what good did having Henne do for Gabbert?!(I hope you saw the faulty logic in that question/statement)
B) This team might not be best addressing some positions (actually one position) the way that I originally thought:
- Is this team really best off addressing the Right Tackle position through free agency? I am not so sure the answer is yes, as I originally thought. Now, while I am far from an expert of blocking schemes, and what team uses what around the league, I can only assume that the "big name" free agents like Vollmer and Loadholt are "big names" because they have shown proficiency and excellence in the seemingly more challenging power-blocking schemes. So, when I think of addressing the RT position, I am not so sure that these "big names" make a whole lot of sense when considering the economics of signing these guys; they will cost a lot, and might not even be ideal candidates, in terms of skillset, for this offensive line. As I think more about it, it might be so that there would be a mid-to-late round OT who possesses the skillset for this scheme and would cost a whole lot less than a guy on the open market. Having said that, two things that I would suggest is that given my understanding of the situation, this team might still do some power-blocking, and so perhaps everything considered, one of these "big names" or a "smaller name" FA (Britton?!! No I am not serious) might actually make the most sense for this team.


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Ever wonder who owns the airplanes that you see at the airport? Do you have a friend that is a pilot? Wanna know what ratings he/she holds?
Try landings.com, scroll to the bottom and click on Databases. From here, you have lots of options. To look up an airplane you must have the "N number", so don't forget to write it down. Anyway, click on "Basic Search" and type in the N-number. Lots of good info.
For info on a pilot, click on "Pilots" (under the certifications section). This selection is above the "Basic Search" link in the middle of the page. Type in your friends info (or partial info) and click Send Query. More good info.
Let me know if you find anything really interesting.
Tuesday, October 02, 2007
Who Owns That Airplane?
Labels: Information
1 comment:
Your blog keeps getting better and better! Your older articles are not as good as newer ones you have a lot more creativity and originality now keep it up!
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The Golf Fix: Bunker Special - March 5, 2012
sending that to us. Let's take a look at what we've got coming up on tonight's show. We're gonna look at bunker basics . We're gonna talk about all the essentials. When you get in here, what's going on? What you just have standard
Daily Brew: Standard Bunker Shot
Hi, I'm Brad Brewer and welcome to The Daily Brew. Our topic today is just the standard bunker shot. Bunker basics . And what we wanna talk about is how to set up correctly and how to move through the strike to give you your optimal opportunity
Bump and Run Bunker Basics
Stanford University teaching pro Josh Zander shares some secrets on how to get out of the bunker in one shot.
Get the job done from the sand in style like Stenson
Henrik Stenson's bunker hole out on 17 sealed his win at the Deutsche Bank, and SwingFix pro Tyrus York has some tips to help you play better sand shots.
Stability, strategy will lead to fairway bunker success
A brilliant fairway bunker shot helped Matt Kuchar capture the Accenture Match Play Championship. Do you know how to execute from a fairway bunker?
Video: More confidence will help your sand game
Johnny Miller doesn't want you to fear bunker shots, and he has some valuable tips to help you improve your sand game.
Don't let anxiety, poor setup ruin your bunker play
Most golfers are consumed with fear when their ball finds the sand, but SwingFix pro Kevin Sprecher is going to help you relax and play better bunker shots.
Excel from bunkers the same way Mickelson does
Phil Mickelson was in complete control of his game in winning the Waste Management Phoenix Open, but his bunker play always stands out.
Tip of the Week: Successfully escaping deep bunkers
LPGA Hall of Famer Annika Sorenstam has some great tips to help you escape from even the deepest of greenside bunkers that you might encounter.
Video: Get your ball up and down from the sand
In this video segment, School of Golf host Martin Hall gives you the best bunker tip he knows, and it came from the great Gary Player.
Breed's Blog: What you can learn from the Ryder Cup
Michael Breed, host of The Golf Fix, uses this week's Ryder Cup to show you things that can help improve your golf game.


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Archive for the 'Oodle' Category
Tips for Finding a Job Online
With unemployment numbers up, would you believe there are thousands of jobs up for grabs? If you don't see that 'Now Hiring' sign in business windows, you'll be surprised at what you can find online at Oodle.
The following are some tips to minimize the time you spend looking and increase the chance that you'll find hundreds of jobs within a 50-mile radius of your zip code:
- Search by job title. This will deliver the results that best match your resume qualifications. If you are searching for a job with an uncommon title, consider searching by keyword to reveal the job titles in the left margin. You can also use a wider geographic radius to find the title you are looking for.
- Change your location. Once you have found (and checked off) all the job titles that you are interested in, move the radius back to your home city/town. To do this change the radius by clicking on the location crumb trail and use the dropdown box, searching from "More Choices." Now click "Find it!"
- Set up an alert. Even when there are currently no results on your search. New jobs are posted each day and an alert will let you know about one that matches your requirements, just as soon as it is posted.
- When you receive an alert with a job you are interested in, click the link which will take you to your original search page with the new listing at the top of the page. The "Details" window will be opened for the new listing. Go to the home page of the listing by clicking the link in the title, or the "See Full Details" link in the "Details" window.
- Each potential employer has a different method for you to apply for the job. Some sites ask you to send your resume. Others will only take an application through their website application form process. Read the job listing carefully and follow the instructions.
- If you are just trying to get your foot in the door to a specific company, search under "Companies" for a list of openings. If you do not see the company you are looking for, widen your search to a country-wide radius from your home town/city, and then use "More Choices" under the "Company" options.
- Finally, when you have found a job and would like to discontinue alert email, simply click the "Unsubscribe" link.
Comcast Expands its Online Marketplace With Oodle Network
We're excited to share the news that Comcast has joined our partner network. Today, Comcast expanded its online marketplace to include tickets and pets powered by Oodle: www.comcast.oodle.com. Now Comcast users have access to the largest compendium of sports, concerts and theater tickets and events on the web.
We're thrilled to have been chosen by this industry leader and look forward to helping them extend their vision for a compelling local classifieds service.
The addition of Comcast to Oodle's partner network of more than 200 leading brands, including Walmart, Facebook, MySpace, and Cox Broadcasting, now gives Oodle access to over 200 million uniques worldwide.
My Interview with Cheezhead's Joel Cheesman
Last week I spoke to Cheezhead's Joel Cheesman about everything from our deal with Facebook to the future of online classifieds and the economy.
The podcast went live today on Cheezhead.com. Tune in and share your thoughts: listen now!
Facebook selects Oodle to power its Marketplace
We are thrilled to share the news that Facebook has chosen us to power Marketplace, their application for online classifieds.
Everyone has things they no longer use that they should give away or sell. Posting to a traditional classifieds site involves meeting strangers, which can be uncomfortable. Emailing all your friends is inefficient and potentially annoying.
This agreement gives us a great opportunity to extend our vision for a community marketplace – a new generation of online classifieds where you can buy, sell and pass along items with people you know or people you at least know something about.
In many cases, you simply want to find a good home for items you are no longer using. In these instances, who you are giving to or selling to is more important than selling to them at the highest price. For example, when a person has extra tickets to a concert, they might prefer to give them to a friend or sell them at a discount to a co-worker. Parents often prefer to give toys their children have outgrown to other parents from their school or neighborhood.
We plan to launch Facebook's Marketplace in Q1 of 2009. They will be great addition to the Oodle Network. This partnership expands our network of online communities, which includes MySpace and Military.com.
Welcome Oodle India and Oodle Ireland!
In keeping with the international theme, we're happy to welcome Oodle Ireland and Oodle India to our international family. Ireland and India are two of our most requested countries and we look forward to them enjoying similar success to our UK and Canadian sites.
Going forward, are there other countries in the cards? If so, which ones? Let's just say that classifieds has a huge audience internationally and it's our vision to wire the Web for classifieds. So stay tuned!
Oodle and CanWest: Perfect Partners
Today we're excited to announce a major partnership with CanWest, Canada's largest media player. CanWest owns the Global Television Network, is Canada's largest publisher of English language daily newspapers, and also owns many other television channels, web sites and radio stations all over the world.
This partnership is strategic for both Oodle and CanWest. Powering CanWest's classifieds will significantly boost Oodle's Canadian footprint, and we will benefit from the great content CanWest will bring into the Oodle network. CanWest will benefit from Oodle's top of the line classifieds platform, our expertise in content aggregation, and having a unified classifieds service across all of their papers and properties.
If you want to see the Oodle marketplace in action on CanWest sites, check out the Canada.com and its regional network, such as Victoria Times Colonist and the Calgary Herald.
Welcome, New Jersey!
The Oodle city and state family now includes all 50 states! We recently launched three new metros, all in New Jersey
Thanks to all of you who wrote in requesting that we add Jersey to our database. Go ahead and check out the new metros: Jersey Shore, Newark and Trenton.
Mobile Classifieds? Oh My!
At Oodle, we believe in the phrase "power to the people." We're sort of like John Lennon that way. So what do the people like? Mobile phones. In fact, in many countries, there are more mobile phones than people.
As the leading classifieds network and as fans of John Lennon (before the Yoko Ono days or maybe during the Yoko Ono days, after Abbey Road but before "Cold Turkey") and definitely fans of Gandhi or the Dalai Lama, we asked ourselves "What can we do that will change the world as we know it?" I'm glad we asked.
See, today, we here at the Oodle UK offices began an experiment with the next phase of classifieds – mobile classifieds. We're launching this service with one of our partners, Magic Radio. The service, which has been developed using technology through Mobiya, allows users to post ads directly into the Oodle network via their mobile phones.
If you live in the UK, all you do is take a picture of your item for sale, describe it, and then text the info to 66121. You'll get a couple more texts asking for your location and keywords to better describe the ad. And voila – we publish it to the web (and it reaches over 1 million potential monthly buyers in a snap).
The process is both easy and cheap – you're only charged normal SMS rates to post an ad. If someone replies to your ad, they're charged .25p. If you get a lead and want to accept it, you'll be charged .25p. An easy sale for only about .50p.
Try out the service this Friday, and listen to Magic FM for the accompanying advert. Also, check out: http://magic.mobiya.co.uk/docs/66121FreeAds.php for more info.
Listings Want to be Free – Update
In a previous post entitled "Listings Want To Be Free," I discussed how "up front" pricing and "fixed fees" will soon be business models of the past.
This morning, another key chapter of this story unfolded — eBay announced it is reducing its fee structure on "buy it now" listings
- Upfront listing fees will be $.35 in September (a 70% decrease).
- Listings will now be online for 30 instead of 7 days.
While press discussion has largely focused on eBay's move into fixed pricing from the auction business, what's more important is their transition to monetizing their business through the back-end transaction fees.
In short, eBay's model is aggressively moving from a pay-to-publish to a pay-for-performance model. Given that eBay is such a large player in the market, we expect that this move will accelerate how pay per performance models are adopted – not just in merchandise (eBay's mainstay), but in other listings categories as well.
MySpace and Oodle: Two Weeks Later
Two weeks ago, we re-launched MySpace's classifieds. The goal for the partnership was to create the best possible classifieds experience for MySpace users – local classifieds from all over the web mixed with the inherently social nature of MySpace. The results and responses from MySpace users have been phenomenal.
Check out some of the Best Of posts from MySpace users.
Looking for some baby fancy rats? Look no further.
Or, if you're in the mood, you could send this guy $1…
Check at all the Best Of posts at Oodle's MySpace profile. While you're at it, become our friend!
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An important part of Medfield's character and appeal is its history which inclues the number of antique houses, such as the Peak House, the Dwight-Derby House, and many others that have occasionally been open to the public on house tours.
On Sunday, one of Medfield's lesser-known antique houses -- the Robert Hinsdale House at 87 Harding Street -- will be open to Medfield Historical Society members for the society's members-only annual holiday party (from 2pm to 5pm).
Although this is a members-only gathering, non-members who join and pay the membership dues at the door are welcome to join the festivities.
The following information about the Robert Hinsdale House has been provided by the Medfield Historical Society in its monthly newsletter.
The property at 87 Harding Street was first deeded to Robert Hinsdale, one of Medfield's original thirteen settlers. Hinsdale left Medfield for the Connecticut Valley around 1670 and, along with three of his sons, was killed there by Native Americans in 1675, during the King Philip War.
The property seems to have passed first into the Barber family and then into the Bullard family. Some 80 years after the original Robert Hinsdale left Medfield, the home returned to the Hinsdale family, having been purchased by Robert Hinsdale, a house joiner by trade, the great-great-grandson of that first Robert Hinsdale.
The history of the house now turns to Robert's grandson, Hinsdale Fisher, who was born in 1786, the only son of Obed and Catherine Fisher, and was named for his grandfather, Robert Hinsdale. It is Hinsdale Fisher to whom the current house is attributed. Hinsdale Fisher was a farmer by trade who taught school in the winter. He died in 1869 at the age of 83.
John G. Hutson, who had lived with Fisher since his arrival in Medfield in 1833, inherited the house in 1866 when Hinsdale Fisher died a childless widower. John's son Herbert succeeded in ownership of the house after the death of his father and retained ownership until he died in 1923.
For more information on local historic homes, to receive the Medfield Historical Society's newsletter, or to join the organization, click here.


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Find more about italian combined with these topics:
- dinners (52)
- quick & easy (25)
- healthy (21)
- european (16)
- event planning (12)
- chicken (9)
- sides (9)
- appetizers (8)
Find more about dinners combined with these topics:
All About "italian" and "dinners"
Grilled Rosemary-Salmon Skewers
If you can find (or grow) them, use sturdy rosemary branches, stripped of leaves, as skewers for these Italian salmon kebabs; theyll add a subtle, smoky flavor that hints of pine. Oil your grill well to prevent sticking, dont...Read More
Homemade Pizza
Enjoy fresh-from-the-oven pizza with these delicious toppings.Read More
Make Your Own Pizza Party
Let all your guests fill personal-sized pizza crust with an array of toppings to make a combination all their own. It's a great pastime for kids' parties and sleepovers.Read More
Dad's Spaghetti Sauce
This is the spaghetti sauce I grew up on, and it is wildly rich and delicious, and I have changed it very little. This recipe makes a huge batch that I freeze in 2-cup portions in Ziploc bags and come a chilly, dark dinnertime, all I have to do is boil a pot of water. I love that. The sauce needs to cook for a long time -- the original recipe actually says 4 hours, though I only do 3. Oregano I don't use, because I don't like it, even though my dad uses it and I love, love, love his sauce even more than mine, because, well, just because.Read More
Squash & Leek Lasagna
If lasagna is just a layered noodle casserole, there's no reason to stand on ceremony. Here's a vegetarian, autumnal version with butternut squash, leeks, pine nuts and Parmigiano-Reggiano.Read More
Throw a Make-Your-Own-Pizza Party
Let all your guests fill personal-sized pizza crust with an array of toppings to make a combination all their own. It's a great pastime for kids' parties and sleepovers.Read More
Family Movie Night: Rock Night
Being a parent doesn't have to mean you're square. Let your family in on a little secret -- that you still know how to rock out. Make it a night that will have your family screaming, "Encore! Encore!"Read More
Spaghetti alla Carbonara
In this version, the eggs are cooked into a custardlike sauce. An extra step, yes, but the technique ensures food safety.Read More
Creamy Asparagus Pasta
Lemon zest ties all the flavors together in this light and creamy pasta. Make it a meal: Serve with a salad of sliced fresh mozzarella and cherry tomatoes tossed with a little fresh basil, balsamic vinegar and olive oil.Read More
Slow-Roasted Cherry Tomato Bruschetta
Roasting tomatoes brings out their inherent sweetness.Read More


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The Rapid Alert System for Non-Food Products (RAPEX)
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Report 22 (Published on: 06/06/2008)
Notification 0753/07 from week 30 in 2007 has been updated.
Notification 0753/07 from week 30 in 2007 has been updated.
Back to report listings
Printable version
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1 0581/08
Category: Gas appliances
Product: Gas grill
Brand: BROIL KING
Type/number of model: Models Signet, Sovereign and Sovereign XL
Batch number/Barcode:
OECD Portal Category:
Description: The recall affects gas grills produced after 2006, with the following characteristics:
- Signet series (models starting with 986xxx): 400 sq. inch cooking surface with 3 burners and drop-down shelves; includes models with side and rear burners.
- Sovereign series (models starting with 987xxx): 450 sq. inch cooking surface with 3 burners and drop-down shelves; includes models with side and rear burners.
- Sovereign XL series (models starting with 988xxx): 600 sq. inch cooking surface with 4 burners and drop-down shelves.
Country of origin: Canada
Fire and burns
The product poses a risk of fire and burns because the bottom of the cooker that contains the burners can melt or crack as a result of a grease fire.
Voluntary measures: Voluntary corrective actions taken by the importer.
2 0582/08
Category: Toys
Product: Wagging Dino
Brand: LEARNING ROAD
Type/number of model: Bar Code 7431938997018
Description: It is a plastic toy in the shape of a dinosaur. The toy is moved on 3 wheels by pushing or pulling a cord with a small plastic handle attached at the end. All parts of the toy are made of multicoloured plastic. Packaging – On the cardboard are the following inscriptions: "Shaking Head", "Wagging Tail", "Wobbly Walk", "Roaring Sound", a pictogram concerning the age restriction (ages over 18 months) and a "CE mark".
Country of origin: China
The product poses a risk of suffocation by strangulation because the free length of the cord is 260 mm, which exceeds the limit of 220 mm.
The product does not comply with the relevant European standard EN 71.
Compulsory measures: Sales ban and withdrawal from the market ordered by the authorities.
3 0583/08
Product: Toy mobile phone
Brand: BENIGN GIRL and ADVENTURE HERO !!!
Type/number of model: No 1108 is affixed on "Benign Girl" toys.
Description: The products are made from solid plastic. The body of "Benign Girl" is painted in white and pink, and has white push-buttons, numbers and symbols. The lid is painted in white and pink and has different coloured stickers of princesses. The body of "Adventure Hero!!!" is painted in red and blue, and has white push-buttons, numbers and symbols. The lid is painted in red and blue and has different coloured stickers depicting 'Spiderman'. The antenna of both brand toys is made from solid transparent plastic. A pink textile cord is affixed to the side of both brand toys. The toys have light and sound signals. The toys are supplied by two button batteries. The lid of the battery section of both brands of toys can easily be opened.
The product poses a risk of choking because the batteries and the lid entirely fit into the small parts cylinder.
The product does not comply with the Toy Directive and with the relevant European standard EN 71.
Voluntary measures: Voluntary withdrawal from the market by the importer.
4 0584/08
Product: Rattles "Bell"
Brand: BABY GIFT
Type/number of model: Barcode 8675406010421, Model TY01042
Description: Baby rattle set of six (6) different plastic toys. All parts of the toys are made of multicoloured plastic. Packaging – On the cardboard are the following inscriptions: a pictogram concerning the age restriction (ages over 3 years) and a "CE mark".
The product poses a risk of choking because during the impact test the product breaks and releases small pieces which may be swallowed.
The product does not comply with the Toys Directive and the relevant European standard EN 71.
5 0585/08
Category: Motor vehicles
Product: Passenger car – Brake switch
Brand: HONDA
Type/number of model: model Civic 4D (model codes: FD1, FD4, FD6, FD7) and Hybrid (model code: FD")
Description: The recall concerns 2006 and 2007 model year vehicles. The list of the VIN of the affected vehicles :
-JHMFD1***6S205089 to JHMFD1***6S214413 -JHMFD1***7S200004 to JHMFD1***7S206651 -JHMFD3***6S200833 to JHMFD3***6S205020 -JHMFD3***7S200007 to JHMFD3***7S201126
-NLAFD7***6W000031 to NLAFD7***6W001320
-NLAFD6***7W900241 to NLAFD6***7W912909
-NLAFD7***7W900031 to NLAFD7***7W900085
-JHMFD4***6S200216 to JHMFD4***6S200807
-JHMFD4***7S200001 to JHMFD4***7S200161
Country of origin: United Kingdom
No pictures are available
The product poses a risk of injuries because the brake switch may fail due to contamination (incorrect application of silicon grease type and amount) which could cause the brake lights not to illuminate during braking. This could result in an accident.
6 0586/08
United Kingdom
Product: Plastic rattle - Tumble tower by Manhattan Toy
Brand: YORK RIVER PRODUCTS
Type/number of model: Item n°206280, UPC code 0-1196442878-6
Description: Clear plastic hand rattle with blue plastic ends. The rattle is 5 inches long and consists of a central tube encasing a blue painted face disc which spins on a purple twisted stick when the rattle is turned. There are colourful beads inside two clear handles with brightly coloured rings on the outside. No packaging but accompanied by a cardboard tag entitled "whoozit Baby's Favourite Friend".
The product poses a risk of choking because the blue plastic end caps of the rattle can break, resulting in small parts which could cause a child to choke.
Two incidents reported.
The product does not comply with the Toys Directive and with the relevant European standard EN 71.
Voluntary measures: Voluntary recall from consumers.
7 0588/08
Czech Republic
Category: Childcare articles and children's equipment
Product: Child's Tom & Jerry bib
Brand: BOCEK
Type/number of model:
Description: Child's bib with a pocket. Made of white polyvinyl chloride (PVC foil) printed with a picture of Tom & Jerry and BOCEK®. Lined with white textile material, trimmed with yellow edging. Proportion 36 x 29cm. The bib is packed in a transparent plastic bag closed with coloured card.
Country of origin: Czech Republic
The product poses a chemical risk because it contains 78.96mg/kg (limit 30mg/kg) formaldehyde. Formaldehyde is absorbed rapidly and can cause irritation, allergic reaction and can damage muscular membranes. It may damage the central nervous system, liver and kidneys.
8 0589/08
Product: Soft toys - Mjakishi kubiki ("Transport")
Brand: MYAKISHI
Type/number of model: N° of Art. : 043 ; Bar code : 4607070490425
Description: A multicoloured textile toy with motifs of transport vehicles (car/bus/airplane). Packed in a plastic bag with a cardboard tag on which is written: Appropriate for children above 1 year, high-quality development toy which does not contain any allergens and which encourages the child's growing. Symbol of maintenance, CE mark, name of importer. Product name only in Russian.
Country of origin: Russia
The product poses a chemical risk because the textile toy contains formaldehyde 90 mg/kg (limit 30mg/kg).
Formaldehyde is absorbed rapidly and can cause irritation, allergic reactions and damage to mucous membranes. It may damage the central nervous system, liver and kidneys. It is a mutagenic substance and has been classified as a probable human carcinogen.
Voluntary measures: Voluntary corrective action taken by the importer
9 0590/08
Product: Toy electronic keyboard
Brand: KEYBOARD M
Type/number of model: Ref.: 2321,
Batch number/Barcode: 8400000023214
Description: A toy electronic keyboard. The product is packaged in a cardboard box. The label reads: "Electronic Keyboard M-3738S". The descriptions are not in Spanish. "Made in China", CE marking, pictograms 0-3 years. Ref.2321. Barcode 8400000023214. There are no instructions for the toy inside the box.
Electric shock
The product poses a risk of electric shock due to accessibility of live parts, because the casing does not have sufficient mechanical resistance and because the transformer is inside the toy.
The product does not comply with the Toys Directive and with the relevant European standard EN 50088.
Compulsory measures: Withdrawal from the market ordered by the authorities.
10 0591/08
Category: Electrical appliances
Product: Electric fan
Brand: GUT MODEL
Type/number of model: GDV032
Description: An electric fan packed in a cardboard box. The label carries the following information: "Box fan gama Silent". CE marking. "Made in China". Spanish-language instructions.
The product poses a risk of electric shock because :
- the gauges can touch the main insulation of the internal parts,
- the timer and speed selector controls are not properly secured.
The product does not comply with the Low Voltage Directive and with the relevant European standard EN 60335.
11 0592/08
Category: Food-imitating products
Product: Bath salts
Brand: DE LAURIER
Type/number of model: Triple Tartelette de Bain. Decadent Chocolate. Triple Tub Cake. Ref. 16194, 120g,
Batch number/Barcode: 5425013556088
Description: Bath salts in the form of chocolate and strawberry cream cakes. The wrapping is transparent plastic. The label on the underside reads "Triple Tartelette de Bain. Decadent Chocolate. Triple Tub Cake, 120 g", and carries the manufacturer's name.
Country of origin: Belgium
The product poses a risk of choking as, due to its characteristic form, appearance, colour and size, the product may be mistaken for a foodstuff. This may lead children to put it into their mouth and swallow it, entailing the risk of asphyxia or obstruction of the digestive tract.
The product does not comply with Directive 87/357/EEC on products which, appearing to be other than they are, endanger the health or safety of consumers.
12 0593/08
Product: Travel adaptor - "continental adaptor"
Brand: DESIGN GO
Type/number of model: 076528231
Description: Travel plug for UK plugs into earthed sockets
Country of origin: Unknown
The product poses a risk of electric shock because the travel plug adaptor (plug part) may overstretch/deform the earthing bracket of the socket outlet. The earthing bracket may therefore no longer provide the intended protection. The metal casing of a device connected to these socket outlets may carry 230 V from the mains supply.
The product does not comply with the relevant standards.
13 0594/08
Product: Gas lamp
Brand: Unknown
Type/number of model: L-200, L-202, L-203, L-205
Description: Gas lamp with blue housing. Height approx. 25.5 cm. Diameter approx. 10 cm.
Country of origin: Greece
Chemical and injuries
The product poses :
- a chemical risk because its mantle contains thorium. The mantles become "crumbly" with use, i.e. they fall apart upon contact. As a result, dust containing thorium can be absorbed into the body through inhalation or ingestion, meaning that radioactive substances may be incorporated into the body causing damage to health.
- a risk of injuries because the metal sheets have very sharp edges.
The product does not comply with the Directive 90/396/EEC on appliances burning gaseous fuels.
Voluntary measures: Voluntary withdrawal from the market by the distributor.
14 0595/08
Product: Devil puppet
Brand: SIMBA® TOYS
1) Devil hand puppet -
Batch number/Barcode: 4006592453091; Article No: 458 5088
2) Devil puppet sold as part of a five-piece hand puppet set - Barcode: 4006592 442156; Article No: 458 4215
1) The "devil" is packaged individually
2). Hand puppet set with five colourful hand puppets in the form of: "devil", "Punch", "grandma", "princess" and "policeman".
The affected "devil" toy is available as an individual product (Article No 458 5088) and the identical item is also available as part of a set (Article No 458 4215).
The head is made of soft plastic; skin colour: red; hair and beard: black; eyes: black, yellow and green; teeth and horns: white; mouth: purple. Cape made of black fabric with two red triangles on the front and a felt collar.
The affected products are only "old goods" packed in a red and blue box with the number 88881101 printed on the bottom of the packaging beside the words "Made in China". The packaging of current products, which are not affected, has yellow elements. The coat has two different materials 1) shiny stiff material with a red apron 2) matt, black material with red stitching on the front.
The product poses a chemical risk because the black textile part of the "devil" hand puppet contains 581 mg/kg 4-aminoazobenzene which is a banned azo dye.
Voluntary measures: Voluntary recall from consumers by the importer.
15 0596/08
Product: Safety gate
Brand: LINDAM
1) Lindam Easy Fit Plus Safety Gate - Model Number LD 145, Argos Catalogue Number 375/3086
2) Lindam Premium Easy Close Safety Gate - Model Number LD 146, Argos Catalogue Number 375/3282
Description: Metal safety gate consisting of a hinged gate section contained in an outer frame, steel construction painted white.
Products are exclusive to Argos Ltd
The product poses a risk of injuries because the hinge that holds the gate within the frame may crack and fail, allowing the gate to fall away from the frame. This would constitute a hazard to anyone passing through the gate at the time, and if the item did not break completely it could lead to failure at a later stage, e.g. if a child was to push or pull on the gate. 14 incidents reported.
Voluntary measures: Voluntary withdrawal from the market.
16 0597/08
Category: Clothing, textiles and fashion items
Product: Child's top (sweatshirt)
Brand: MISS GANG
Type/number of model: Unknown
Description: Child's top (sweatshirt) from a set, consisting of a T-shirt and two trousers. The sweatshirt has long sleeves, a hood and strings in the hood area, red colour and decoration "DREAM ON"
The product poses a risk of suffocation by strangulation because it contains draw strings.
17 0598/08
Product: Plastic playset – "Jungle King"
Brand: B.C.I.C.
Type/number of model: Model TJ208-197K
Description: Toy set of eight different plastic toys. Contains a shotgun, bow, a knife, small deer, a compass, a cactus, a set of six red projectiles and three arrows. Packaging – The cardboard contains the following markings: a pictogram concerning the age restriction (Ages Over 3 Years), a warning – Choking Hazard small parts and a "CE mark".
The product poses a risk of choking because the length of the projectiles is 42 mm, while the minimum required limit is 57 mm.
18 0599/08
Product: Plastic tiara
Brand: "BARBIE"
(1) barcode 8 697410 285947,
(2) barcode 8 697410 287514 and identification number Y-BR801-9J,
(3) barcode 8697410284292, article number BRT 557.
(1) Plastic tiara for holding back hair with "Barbie" trademark, barcode 8 697410 285947, and a label in Bulgarian with following information: product type – tiara "Barbie", warning: "not suitable for children under 3 years old" and additional label with identification number Y-BR801-6J ,
(2) plastic tiara for holding hair, "Barbie" trademark, barcode 8 697410 287514 and identification number Y-BR801-9J
(3) child's plastic tiara for holding hair, "Barbie" trade mark, with a label in Bulgarian – "Barbie" tiara, warning: "not suitable for children under 3 years old", barcode 8697410284292, article number BRT 557.
Country of origin: Turkey
The product poses a risk of injuries because it has sharp pins on the inner surface and a sharp cutting edge. As a result there is a risk that children may be hurt.
The products do not comply with the European standard EN 71.
19 0600/08
Product: Fryer – "Smart Clean Fryer"
Brand: TEFAL
Type/number of model: FR400915 and FR400916
Description: Domestic electric deep-fat food fryer.
The product poses a risk of fire because of loose connections in the mains terminal block which causes arcing, leading to melting and burning of the surrounding plastic insulation which could drop onto the plastic moulding beneath and melt or burn a hole in the base of the appliance. A large hole in the base would provide access to live parts, which could present a risk to the user, bearing in mind that the product may be alight and smoking and somebody, in a panic, could try to lift the product to put the flames out without disconnecting it from the mains supply.
The product does not comply with the Low Voltage Directive and with the relevant European standard EN 60335.
Voluntary measures: Voluntary recall from consumers by the importer.
Press release has been issued.
20 0601/08
Product: Pirate mask
Type/number of model: Model: 2616, Bar code: 8412672026165
Description: Pirate mask with a hat with a red band. The label bears the following wording: 'This is not a toy; it is for fancy dress. Not recommended for children under 14 years of age. Keep away from fire.' The importer identification, the wording 'Made in China' and the barcode also appear on the label.
Suffocation and burns
The products poses a risk of:
- suffocation because the ventilation area is less than 1 300 mm² ( required by the standard),
- burns because the hat and band fail the flammability test.
21 0602/08
Product: Plastic doll
Brand: TOYS
Type/number of model: Item no. in invoice: B123467
Description: A plastic doll with blue or pink hair in a clear plastic bag.
This product poses a chemical risk because:
- the plastic material in the head of blue-haired doll contains 39% by mass of bis (2-ethylhexyl) phthalate (DEHP),
- the plastic material in the head of pink-haired doll contains 31% by mass of bis (2-ethylhexyl) phthalate (DEHP) and 8.9 % by mass of dibutyl phthalate (DBP).
According to the Chemical Restrictions Directive 76/769/EEC, certain phthalates in toys are prohibited.
Compulsory measures: Import rejected by the customs authorities.
22 0603/08
Product: Child's sleeping bag
Brand: ВABY KINGDOM
Description: A child's sleeping bag with a textile tightening cord, designed for children up to 2 years of age, with a lining and a zip. Depending on the size, there is also an additional zip for the feet. The item is sold in a transparent, polyethylene bag with a label attached containing the following information: Made in Bulgaria, composition - 100% cotton.
The product poses a risk of suffocation by strangulation because:
- the cord ends have not been secured against unravelling,
- the cord has not been secured properly and comes out of the loops,
- the cord ends are longer than 255 mm and 330 mm and consequently pose a serious risk to children under 7 years of age because if the cord winds around the child's neck it may cause strangulation.
The product does not comply with the European standard EN 14682.
23 0604/08
Product: Remote controlled mini-helicopter - Mini super infrared radio controlled helicopter
Brand: HELICOPTER
Type/number of model: 4015655031497, Art. Nr. 3149
Description: The remote controlled helicopter is 17 cm long and 6 cm high and weighs around 10 g.
The product poses a risk of injuries because an encircling ring for the rotary blades on the helicopter is missing.
24 0605/08
Product: Double push-chair for dolls
Brand: BABY CAR
Type/number of model: NO. 1210-43
Description: The double push-chair for dolls has a metallic frame and plastic decorations; the seat part is made from coloured (pink) textile. The product is packed in a transparent plastic bag closed with a cardboard tag.
The product poses a risk of injuries because:
- some edges of the metallic construction are not protected by plastic caps,
- the metallic tube diameter enables entrapment of children's fingers,
- the pushchair can be partially unfolded without activating the blocking device. The child may think that the pushchair is fully open and, while playing, be injured if the pushchair unexpectedly folds up.
- the diameter of the plastic packaging is 470 mm, its average thickness is 0.032mm.
The product does not comply with the European standard EN 71.
25 0606/08
Product: Plastic inflatable toy – "Crawl-a-Long Roller"
Brand: BLOSSOM FARM
Type/number of model: 5-050048 193955. 113386 0406
Description: Baby's plastic inflatable "crawl-a-long" toy for ages 6-18 months.
These products pose a chemical risk because it contains di- "isononyl" phthalate (DINP) in a concentration greater than maximum limit of 0.1% by weight. Although not intended to be placed in the mouth, this toy could clearly come into contact with a child's mouth and be sucked on.
According to the Chemical Restrictions Directive 76/769/EEC, certain phthalates in toys are prohibited.
Voluntary measures: Voluntary withdrawal from the market.
26 0607/08
Product: Musical game – "Baby Play Thing"
Brand: SUPER TOYS
Type/number of model: Item n° SL-0682A / n° 2002E, Bar code 5291410028141
Description: Assembled musical toy for a child's bed. Packaging: the cardboard contains the following information: a pictogram concerning the age restriction (ages over 3 years), a warning: choking hazard small parts and a "CE mark".
This product poses a risk of choking because it releases small parts that fit into the small parts cylinder. The toy is clearly intended for children under 3 years old.
The product does not comply with the Toys Directive and the relevant European standard EN 71.
27 0608/08
Category: Laser pointers
Product: Laser pointer
Brand: LASER POINTER SUPER POWERED
Description: Laser pointers – a key chain with 12 interchangeable points, marked as He-Ne laser, wavelength 630-680 nm, output 1 mW, class II. The points have various motifs (eg. butterfly, hand, ant, etc.) The laser pointer works in a continual regime. Packed in a plastic container with a transparent lid and in a cardboard box with a transparent front part enabling the product to be seen.
Damage to sight
The product poses a risk of damage to sight because the measured values of a direct beam exceed the limit value for eye exposure. In addition, the product has insufficient safety warnings and user instructions. In case of inappropriate use, especially by children, the beam could directly strike an unprotected eye and damage it.
Voluntary measures: Voluntary withdrawal from the market ordered and recall from consumers.
28 0609/08
Product: Ball and racket
Type/number of model: 736327 bar 360,
Batch number/Barcode: 5996033413618
Description: Inflatable PVC ball with cartoon figures and a racket. Dimensions: ball diameter: approx. 31 cm; racket: 24.5 x 11.5 x 0.7 cm.
The product poses a chemical risk because the mouthpiece of the inflatable ball contains 28.8-31.9 % by weight of di-"isononyl" phthalate (DINP).
Enforcement is a top priority of the EU Consumer Policy Strategy 2007-2013. Both measures leading to RAPEX notifications and measures which come to the attention of the Commission and other Member States as reactionsare indications of enforcement activity in the Member State concerned.
In order to give a better view on the overall level of enforcement, including the follow-up activities of the national market surveillance authorities, the Commission RAPEX team has decided to publish on the RAPEX website also the names of the countries that have found the notified product on their market and have taken appropriate measures (and have submitted a reaction to a RAPEX notification as a consequence).
Information about the reacting countries is available in the RAPEX weekly overviews in the column 'Products were found and measures were taken also in'. The Commission RAPEX team will publish reactions sent (from May2009 onwards) to 2009 RAPEX notifications.
DISCLAIMER: If not specified in the report, the risk and non-compliance refer to a risk for consumer health and safety
IMPORTANT NOTE: Please be aware that proprietary brands, designs and logos that appear in this listing may have been used in violation of intellectual property rights and thus without the legitimate owner's knowledge and/or permission.
The official contact points of the Member and EFTA-EEA States provide the information published in these weekly overviews.
Under the terms of Annex II.10 to the General Product Safety Directive (2001/95/EC) responsibility for the information provided lies with the notifying party. The Commission does not take any responsibility for the accuracy of the information provided.
Die in dieser wöchentlichen Übersicht veröffentlichten Informationen wurden von den offiziellen Kontaktstellen
der EU- und EFTA-EWR-Mitgliedstaaten mitgeteilt. Gem äß Anhang II Ziffer 10 der Richtlinie über allgemeine
Produktsicherheit (2001/95/EG) ist der meldende Mitgliedstaat für die mitgeteilten Informationen verantwortlich.
Die Kommission übernimmt keine Verantwortung für die Korrektheit der bereitgestellten Informationen.
Les informations publiées dans les rapports hebdomadaires sont fournies par les points de contact officiels des
États membres de l'UE et de l'AELE/EEE. Au titre de l'annexe II.10 de la directive relative à la sécurité générale
des produits(2001/95/CE), la responsabilité des informations fournies incombe à la seule partie notifiante. La
Commission décline toute responsabilité quant à l'exactitude des informations fournies.
Links to the RAPEX website may be created subject to respect of the conditions set out at the following web address:
Downloading and reproduction for non-commercial or commercial redissemination of any textual and photographic material contained in the RAPEX notifications are subject to prior permission.
The information contained in the weekly overviews may not be adapted or modified by the user. Translations of the RAPEX notifications from the original English-language edition published on the RAPEX website are subject to the conclusion of a free of charge licence agreement.
For permissions or licences, requests shall be addressed to: email@example.com
Links auf die RAPEX-Webseiten sind vorbehaltlich der Beachtung der Bedingungen zulässig, die Sie unter folgender Adresse finden:
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Weiterverbreitung von Texten und Fotos in den RAPEX-Meldungen unterliegen der vorherigen
Die Informationen in den Wochenübersichten dürfen nicht angepasst oder verändert werden.
Übersetzungen der RAPEX-Meldungen aus der ursprünglich veröffentlichten englischsprachigen
Fassung sind nach Abschluss einer gebührenfreien Lizenzvereinbarung zulässig.
Anträge auf Genehmigungen oder Lizenzen sind zu richten an: firstname.lastname@example.com
Il est possible de créer des hyperliens vers le site web consacré au système RAPEX, à condition de
respecter les conditions décrites à l'adresse suivante:
Le téléchargement et la reproduction à des fins de rediffusion, commerciale ou non, de tout contenu
textuel ou photographique dans les notifications RAPEX doivent faire l'objet d'une autorisation
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l'utilisateur. La traduction, à partir de la version originale en anglais, des notifications RAPEX publiées
sur le site RAPEX est soumise à un accord de licence à titre gratuit.
Pour demander une autorisation ou un accord de licence, veuillez vous adresser à: firstname.lastname@example.com
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