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For questions on LegalZoom's Perspectives, or to set up an interview with a company representative, please contact firstname.lastname@example.com
LegalZoom offers affordable, high-quality legal document services and other business solutions. Despite the efforts of a few, isolated members of the North Carolina State Bar, North Carolina consumers, like consumers from all fifty states, continue to have the option to choose LegalZoom. LegalZoom furthers the well-established right to represent oneself and will continue to fight for the public's right to represent themselves and to accomplish their legal goals using self-help services.
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We believe that the Pennsylvania Bar Association's recently issued opinion regarding online legal document preparation does a disservice to both consumers and lawyers. Disturbingly, the Committee issued an opinion alleging illegal activity without complying with the most basic rules of due process. Predictably, many of the factual assumptions underlying the Opinion are inaccurate; the Opinion cites inapplicable case law; and the analysis ignores case law affirming the right of individuals to represent themselves in their own legal matters.
On the cover of the September 2010 issue of California Lawyer Magazine, the following headline appears in bold red type beneath a picture of the LegalZoom founders: "Will These Guys Put You Out of Business?" LegalZoom's answer is the same as it has always been – No.


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Product Announcement from Centryco Inc.
Centryco expands their product line with the capability to produce very small bellows utilizing a vacuum forming technology.
These polyurethane-based bellows provide fully sealed protection with excellent fatigue and wear characteristics. Abrasion resistance and tear strength provide millions of cycles without failure even in the most severe applications.
Bellows can now be made with diameters as small as 5mm and up to lengths of approximately 125mm.
Centryco's miniature bellows can be custom designed for use in numerous applications, and offer excellent resistance to hydraulic and motor oils, grease, ozone, microbes, and hydrolysis processes among other contaminants.
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Greyhound has lump that's growingby Dr. Stephanie Correa
Question: I adopted "Mama" three years ago from Elite Greyhounds. She IS my life. Almost a year ago, we noticed a lump on her left neck. I brought her to the vet. He biopsied it, said it was OK. The lump now is quite large, and he said she was too old (13 now) to operate. It does not seem to bother her; she eats and poops very well.
She is losing some weight from vet visits, other than that, she's "my baby," and I'm so lucky to have found her. PetSmart advised to start giving her vitamins to help boost her system. They are GNC Mega Multivitamin Chewable tablets for senior dogs. Is this OK? — Jane
Answer: What a great adoption you made. Greyhounds make wonderful pets and you have had your dog for 10 years now! Good for you.
Do you know what type of biopsy was performed on the mass on Mama's left neck? There are two types of biopsies. One is called a fine-needle biopsy. When this procedure is performed, a needle is inserted into a mass and some cells are removed. The cells are ejected onto a glass slide and sent for evaluation. This biopsy is non-invasive and does not require anesthesia. There is no incision and there are no sutures needed. With this procedure, though, it can be difficult to get a large sample of cells. Sometimes the cells obtained do not represent what is actually present in the mass. There is a 15 percent chance of getting a false negative result with this procedure.
The second type of biopsy procedure is called an excisional or incisional biopsy. This is when a piece of tissue is removed and sent to a pathologist. Surgery is required and some type of sedation is usually performed. There are sutures used. This is more invasive than the fine-needle procedure, but is less likely to obtain a false negative result. The other benefit of this procedure is if there is cancer present, the cancer can be graded and a more exact diagnosis given.
Since the mass on Mama's neck is growing, ask your veterinarian which type of biopsy was performed. If a fine-needle biopsy was performed, then either an excisional or incisional biopsy could be performed to obtain a more specific diagnosis. If this has already been done, and a negative cancer result obtained, then we will need to decide if it will need to be removed at some point so that Mama does not become uncomfortable as a result of the large mass.
In answer to your final question regarding vitamins, if Mama is eating a well-balanced diet, she probably does not need further supplementation. A geriatric canine vitamin will not harm her in any way, though, and can safely be administered to almost all dogs. Check with your primary care veterinarian first.Stephanie Correa, DVM
Board Certified in Oncology
Animal Cancer Care Clinic
Read more articles by Dr. Correa | Ask her a question


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I have recently been diagnosed with fibromyalgia and arthritis in both of my knees, i am active duty military?
and my unit is still trying to deploy me, don't get me wrong i originally joined bc i wanted to deploy however, i am in an excruciating amount of pain even in a more relaxed environment, i honestly believe that deploying me would be like throwing me to the wolves, does anyone have any suggestions as to what i should do?
Posted 3 years ago in Other by MrsKitten
There are a few new medications that are on the market for Fibromyalgia.One is called Lyrica.Are the military doctors aware of your condition?I am not familiar with the military rules on deploying people with arthritis and other ailments.The only other medicines for arthritis are anti-inflammatory and these do have side effects as does the medication, Lyrica. You really didn't explain too much about the military doctors and what their recommedations are.
1. Do you have access or insurance / champus to cover a civilian physician appointment? If so I would see a civilian Orthopedic Specialist for a SECOND OPINION and treatment of these problems. Most insurances do cover a second and even a third opinion appointment.We were in the military for 20 years so that is why I am suggesting a CIVILIAN Orthopedic Specialist instead of a military one. I'm sure you understand what I mean. Make sure you get a copy of the medical exam and teatment from the civilian doctor and keep a copy for your OWN RECORDS and make a copy to be included in your military records. I do advise that you have a copy made of your current military record addressing all the test and medical diagnosis of this problem and any other long term health issue you have, to keep for your OWN RECORDS as I have seen many such records disappear through the years. These records are very important for your retirement or for getting out of the military for medical reasons for without them you have no proof that this medical problem happened while you were in the military. You might have your own personal copies stored with your parents or in a safety deposit box. 2. If you do not continue to see your military physician with your complaints of pain, they will take your problem lightly and think your really aren't in as much pain as you say.Continually going to the physician will let them know that you are in pain and need some help. Ask your physician if physical therapy will work for you to help alleviate the pain. That usually takes from a few weeks to about a month to see if it works. If you do go to the civilian orthopedic specialist you might also ask them about physical therapy. It is my understanding that the military can't send you anywhere if you are in treatment for a physical problem so that is why I am suggesting the physical therapy.I know many people who have fibromyalgia and many that have arthritis and I have even cared for people with arthritis and sometimes their pain is excruciating. I do know that worry and stress really does make the problem worse, and that nighttime seems to be the worse time for pain or if during the day they are doing some activity that moves or stresses those areas.Another thing is about your knees make sure those are checked again to make sure it is arthritis and not some other problem or broken cartledge in the knee that can only be relieved with surgery.I do know that many patients do get some relief from correcting their diet and finding what foods affect their fibromyalgia and arthritis as these are immune system problems.Many people use a vegetarian diet for fibromyalgia and arthritis but you really have to make sure you do it correctly and get all the nutrients like vitamin B12 and calcijm that you need. Some people are affected by white potatoes, strawberrys, milk products, wheat products, sugar and more so as you see many things can affect your body if you have immune problems. You might want to go to your local health food store and see what they suggest.I will put you on my prayer list.
Arthritis and fibromyalgia? I can't believe that nor do I. Not at your age. They are just wrong, wrong, wrong!!! You don't have either of those things. You have tendons that have shortened up in your kneecaps pulling them up on your knee and into it as well, the part that is sending you into all kinds of pain and not being able to lift your knees the way you should. Once you release the tendons your knees will be fine. Here is how to do that:Kneecap: (Use a chair that has no cross members on it.)While sitting start with your leg out in front of you extended out to a comfortable length. Wrap your hands around it so you leave a open working area. Place your thumbs about two inches behind your knee and press into the top middle of your leg hard and hold. Relax. After 30 seconds, slowly slide that leg back until it is pulled up under the chair as far as you can make it go. Then release the pressure but hold your leg there for one minute longer.Be sure to keep a good pressure on them the whole time, especially when you are bending your knee, for that is when you are putting the length back into the tendon. Of course if you do these things they are going to think you were faking it before. If they believe you then you can ask them if they need one more good man in the service for you met one.
i'm surprised you don't get a medical dischargeplease clarify--do you only have pain in your knees or is it widespreadi wouldn't rush to tru fms medswhile it is a very real condition--it is highly over diagnosed by idiot docs who use it as a general label for painif you ahve 2 bad knees that can cause starin on teh rest of your body--and therefore widespread and faitigue--but that doens't mean it is fibrothere are other treatments for arthritis (i assume its osteo since its only teh knees)KIDS CAN GET ARTHRITS--ever hear of JRA juvenile rhemtoiod artritis...my knee and foot have been arthritc (osteo) since my teens form injuries--anyone who says that is not possible is ignornati ahve had fibro since i was 5---so you are not too young
What is FibromyalgiaFibromyalgia is a complex, chronic, and disabling disorder. It causes widespread pain and stiffness in the muscles, tendons, and ligaments, along with poor sleep and fatigue.
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Police attackers return to court
KINGSTON, Jamaica — Four people accused of stabbing and assaulting a police constable in downtown Kingston appeared in the Corporate Area Resident Magistrate's Court Monday.
The four allegedly attacked the policeman because his girlfriend refused to purchase an item of clothing.
When the case was called up, two of the four accused — store owner Sandra Smart and Jerome Carwin — notified the court that they would, on Tuesday, apply to have their bail conditions varied so they could travel abroad for business.
The court was told in September that the cop and his girlfriend entered a store and the woman asked to fit a blouse that she intended to purchase.
However, she was told that the blouse was the tight-fighting type and as such she could not try it.
An altercation developed between Smart and the cop's girlfriend.
The policeman, who was in plain-clothes, attempted to part the two women when Carwin came from outside the store and allegedly stabbed him in the shoulder.
Seventy-three-year-old Joyce Millings and 18-year-old Sashayle Gayle allegedly joined in on the attack.
The policeman had to be hospitalised for a day after being rescued by another storeowner.
The passports of Smart, 48, and 34-year-old Carwin were seized when they were offered $250,000 bail each.
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Town Square
Camp Parks Night Time Training?
Original post made by Stacey on Apr 3, 2009
on Apr 3, 2009 at 9:08 pm
I was wondering what is going on after hearing helicopters fly over so many times. One is pretty close to here right now.
on Apr 3, 2009 at 9:10 pm
I think they're a lot lower than that! They are flying right over my house and I think I could see the whites of the eyes of the pilots, so to speak.
on Apr 3, 2009 at 9:12 pm
Stacey is a registered user.
The last one I saw looked like it was at about 500 ft right over Santa Rita!


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I've been trying to figure out all day and all last night why this one little loss hurts so much. We didn't get blown out, we came up short by one or two missed (or late) tackles on 2 two point conversions, we missed one field goal, we simply lost by one point... so why does it hurt so much?
I believe the answer lies in the lies of the BCS. We as Bronco Nation have been brain-washed into believing this BCS system. Not that we believe it's right or good by any means, but the belief we have bought into is that the season is meaningless unless we go to a BCS (and win) game.
Do we the fans care about the money part of the BCS? Not really, yes we like better facilities, but honestly we could care less as long as Coach Pete stays around. So what is the big deal about BCS games? The big deal that we've bought into is the belief that the season and/or the team is only a success (elite team) if we play in a BCS game. That's a load of BW.
Why should we measure our success by what the BCS elitists tell us? We as Bronco Nation hurt because we spend hours upon hours arguing that the Broncos are a success, an elite team, that they belong, but we feel that "we" need to "prove" this and the only way to "prove" is for the football team to go undefeated and play in a BCS game. "We" can't control anything, that also might account for part of the hurt. The BCS has essentially required a non-AQ school to go undefeated to play in a BCS game. That fact, in combination with measuring our success by going to a BCS game, is why we are hurt. We all know it isn't right, but we still hurt.
It's one game. We will all move on. We moved on from the Nevada loss didn't we? When we understand that we have bought into a lie of how to measure the success of a team and realize that reality will never measure up I believe that we as Bronco Nation will enjoy Bronco football more.
The reason that I believe that we have bought into this lie is simply this: We feel that Kellen and the rest of the Seniors, and even simply the rest of the team, deserve more than what we think they will ultimately get at season's end because of this one loss. And they do. Kellen, IMO, deserves the Heisman. We want the rest of the world to love the Broncos like we do. We want outsiders to see how deserving the team is. Some will, some won't, that is just reality.
We as Bronco Nation need to stand united and not let the outsiders bash and demean the team. We need to not measure success by the way outsiders like to measure success. For goodness sake, we've lost 3 games in the last 4 years. How many other teams can say that, regardless of the "level" of competition? We are a great team, an elite team! These Seniors deserve to go out in style and the only way for that to happen is if Bronco Nation knows our true measure of success. We are a non-AQ and quite possibly will be ranked 10 or 11 in the BCS rankings with one loss. That's something that even 5 years ago would have beeen a dream come true and now it has become a downer, a disappointment.
These are my thoughts as I try to move on. I will be honest, I hurt. I invest too much of my heart into this BCS BW, needing the team to prove itself, so and this might be a big one, so that we as Bronco fans feel justified in saying we're an elite team. This is America, we are free to have our opinions whether the rest of the college football world agree is up to them, they are all human just like us. We have a right to our opinion.
So Bronco Nation I say to you, stand up an say with pride forever and always, "We are an elite team!"
Send the Seniors out the way they deserve, knowing the love and appreciation we have for them!
Leave me your thoughts and opinions.


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When I was a cub reporter of only 22 in Colorado Springs, I worked with a larger-than-life assistant city editor whose voice and laughter bounced around the newsroom's walls.
I was still learning the trade, but Jim Bishop, who went on to become city editor and deputy managing editor at the Colorado Springs Gazette Telegraph, had mastered it already. He went on to edit a feature project that won the Pulitzer Prize, journalism's top honor.
The reporter on that project, Dave Curtin, said this of Bishop in his obituary: "There are some editors you want to work hard for, just because of who they are. Jim was a stand-up guy and an inspirational editor who always stood behind his reporters. He was a hero to all of us because of the way he treated us."
Of course, many in the Crossroads know Bishop because he served as managing editor and then executive editor of the Victoria Advocate from 1990-2005. When I arrived as editor of the Advocate in April 2007, I was surprised and delighted to reconnect with my old mentor.
Bishop had semi-retired by then, but he still wrote beautiful columns and editorials for the Advocate. I sought him out for counsel about my new job, and he was ready, as always, with a quick smile and reassuring words. He never once offered anything approaching even a hint of criticism, even though he surely had to sigh sometimes at the poorly turned phrase or outright mistakes he saw in the newspaper he formerly steered so well.
I saw Bishop less frequently as his health deteriorated. While attending his memorial service Friday at Rosewood Chapel, I thought about the legacy he and those before him have left during the Advocate's 167 years. How can any one person possibly measure up?
The answer, of course, is no one can. A newspaper is like an octopus with tentacles that spread in every direction every day while reaching back into a past long forgotten and stretching toward a future as murky as the depths of the sea. An editor tries to direct these tentacles, but it's a struggle none will ever proclaim he's won. You rise each morning peering at the ink stains while offering a silent prayer that no previously unseen horror managed to slip onto the page.
An old editor is at rest now, finally free of deadlines. His legacy lives on in the lives of the thousands he touched.
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Manny Diaz on Depth Chart Acrimony
The coordinators sat down with the media today before this afternoon's practice session. Manny Diaz touched on the depth charge topic. On if the players aren't worrying about the depth chart at this point: "I mean, what difference does it make? In reality, how we rank our players on August 1st or August 15th or September 1st, to me it's really irrelevant. Because once the game goes on, things are so dynamic. I actually showed the linebackers a couple days ago, our season opener last year at Mississippi State and I made a point that in the first series we lost our starting corner. In the second series we lost our starting middle linebacker. Our second team middle linebacker was out for the game already anyways, so we had a third team guy that nobody would talk about on a day like today, because no one wants to talk about a third string linebacker. Well that guy played the whole game. So we're trying to press that up on the players. The least important thing on defense is who runs out there on the first play of the game because we intend to play a lot of people. To me what's more important is can we send you across the line. That's what matters. Are you good enough to go across the line? Where if I send you in, the rest of the players look at me and think, "That guy is crazy." Or when you go in, somebody is coming out in turn, they'll think, "Oh, I'm glad that guy is going in because I trust him." So to me, that is the line we're working on right now. That does change every day. Bottom line is do I, and more importantly, does the locker room trust you when you go in that you can represent our defense the way we want to be represented." Right on, right on.


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South Carolina ETV
The People's Pharmacy
Wednesday - February 08, 2012 at 7:19 am
If you've every had questions about how your prescription drugs may interact or wondered if there's a natural alternative, then The People's Pharmacy website is a good place to start your research. Offering a wealth of health topics and headlines, the site is informative and interactive. Listen to podcasts on the show's website, or hear the full program Saturday mornings at 7 on the ETV Radio News stream and Sunday afternoons at 4 on the ETV Radio Classical stream.
PODCAST HELP - If you can't view the flash player, click here to open the mp3 file OR subscribe to the podcast feed.


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New day. New Daily Deals. Get them before they are gone!
New Customer ? Start Here.
Can't find what you're looking for? Shop all ink and toner cartridges by brand
New day. New Daily Deals. Get them before they are gone!
Item: 134403 Model: 3022-08
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This Web site is intended for use by US residents only. See International Sites. See our delivery policy for full details. Copyright 1998-2014, Staples, Inc., All Rights Reserved.


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Following features are presented*:
- creating Groups & Classes with a simple keyboard shortcut
- generating Properties
- generating Classes on the fly
- automatic Imports
- using template from Xcode
- smart detection of missing protocols
- extracting variables and methods
- smart navigation
Almost all commands are issued with keyboard shortcuts, which are shown throughout the screencast.
* Sorry for the bad quality, I only noticed after encoding the screencast. I hope you like it anyways


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From CHN: Cahoon enjoying life after coaching
- Updated: November 13, 2012
"So this is what you guys do?" quipped former Massachusetts head coach Don Cahoon at a small group of media members enjoying overflowing plates of food prior to Boston University's 3-1 win over Merrimack last Friday.
"I wish I knew, I would have joined you a long time ago."
Cahoon made his television debut on Friday as the color analyst on Merrimack's television broadcast. For the first time in nearly 30 years, he isn't behind the bench of a college hockey team.
[Click here to continue reading]
← Previous Story From CHN: UConn adjusts without Marshall


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HURLOCK, Md. - A search warrant in Dorchester County, lands two Hurlock men behind bars.
The Dorchester County Narcotics Task Force searched a home on Circle Drive in Hurlock where they found 27.7 grams of crack cocaine, 13.3 grams of powdered cocaine, paraphernalia, and $317 in cash, along with 41-year-old Elmer Young III. The Task Force also reportedly seized a 2008 Dodge Charged in regards to the case.
Young was charged with possession with intent to distribute cocaine, possession of cocaine, and possession of paraphernalia. He is being held on $75,000 bond.
A second person was also arrested at the home, 64-year-old Elmer Young Jr., who was reportedly wanted in Worcester County for failure to appear in court. He was held on $2,500 bond.


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Goodgame CafePublished on October 23, 2010. Played 7480 times.
If the game you are trying to play is not working, browse our Help / FAQ page.
Open your own Cafe and amaze your customers with your cooking skills. Hire your friends and shop for ingredients right now! Decide what's on the menu today and grow your business. Your Cafe will be the most popular meeting point in town!
Category: ActionPuzzleSimulationGirl


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As a kid, I couldn't even flip a page of a book if it had a picture of a frog on it. So when I see people holding toads or whatever with their bare hands, up to now, the five hairs on my body stand on end and I get all anxious/nauseous.
Kermit the Frog, however, is an exception because he is made of felt and ping pong balls.


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Identification And Targeting Of Adipose Stem Cell Markers For Breast Cancer Therapy
Grant Mechanism:
Postdoctoral Fellowships
Scientific Abstract:
Obesity, marked by outgrowth of white adipose tissue (WAT), is associated with increased breast cancer progression. The mechanism of obesity effect on the morbidity and mortality of cancer is uncertain. WAT has been recognized as a source of adult stem cells of mesenchymal origin, termed adipose stem (stromal) cells (ASC). Circulating vascular precursor cells, similar or identical to ASC, have been recently shown to be capable of homing to tumors and promoting the formation of cancer vasculature, which is required for expansion of tumor mass. We propose that WAT has a direct positive effect on tumor growth as a source of ASC that are recruited by tumors to participate in blood vessel formation as vascular progenitor cells. Our objective is to use clinical patient samples to test the role of ASC in obesity-cancer interaction. We will also use mouse models to determine the effect of WAT content reduction on ASC circulation and breast cancer progression, which will test our hypothesis. As a result of this study, the role of ASC in breast cancer progression will be tested, our understanding of obesity as a cancer risk factor will be advanced, and a novel approaches to breast cancer management will be explored. We will identify and characterize new ASC ligand/receptor systems to build the platform for ASC targeting with the ultimate goal of preventing ASC-mediated induction of cancer progression. These new ASC markers may become universally useful for imaging and prospective isolation of patient stem cells. The mechanism of WAT influence on cancer progression has not been systematically explored. Here, we propose to investigate the role of ASC in breast tumor growth and to design an approach to ASC targeting. Specifically, we will: (1) Explore whether ASC are mobilized from WAT by obesity and breast cancer; (2) Test whether breast caner progression can be modulated through WAT depletion; and (3) Develop an approach to ablate ASC in vivo through peptides targeting ASC markers. For Specific Aim (1), by using patient blood samples, we will explore whether the frequency of ASC in the systemic circulation is elevated by obesity and breast cancer. Multi-parametric flow cytometry on peripheral blood mononuclear cells, combined with culture colony-formation and differentiation assays, will be used. For Specific Aim (2), ?molecular liposuction? with a WAT vasculature-targeted proapoptotic peptide developed by our group (Nat. Med. 2004,10:625-32) will be used to test the effect of WAT on cancer progression. By inducing obesity with high-fat diet in several breast cancer models (MMTV-TGF-alpha transgenic mice, murine EF43.fgf4 mammary breast carcinoma allografts, and human MDA-231breast carcinoma xenografts), we will establish tumors in the obesity background and then perform the experimental WAT depletion. Tumor analysis will be then performed to assess whether obesity reversal via reduction of the amount of WAT inhibits or promotes tumor growth in animals carrying breast carcinoma. In parallel, to determine whether ASC escape the WAT cytoablation treatment and become avalible for tumor vasculogenesis, we will quantify ASC content in blood of mice treated with the proapoptotic peptide. Finally, to isolate ASC-targeting peptides in Specific Aim (3), we will employ our exclusive expertise in selecting combinatorial peptide libraries displayed on bacteriophage to identify molecular interactions that occur at the ASC surface in vivo. As a logical evolution of this study, we are planning to eventually explore ASC as a potential therapeutic target. We will direct the pro-apoptotic peptide with an ASC-targeting ligand to ablate ASC in mouse breast cancer models. The experimental strategy proposed here to deplete WAT and explore the response in the course of breast cancer progression will make it possible to uncouple the presence of WAT in the body from the obesity-inducing factors (diet). This study will, for the first time, directly assign the role of WAT in breast cancer. Furthermore, we will look into possible new biological bases of breast cancer progression by testing the role of ASC in the WAT-tumor crosstalk. Because the possible mobilization of ASC in obesity so far has not been tested or even proposed, this will be the original, highly cited, study measuring ASC in circulation. If observed, inhibition of tumor growth by targeted ASC depletion will strongly support our theory that ASC, rather than adipokines, play the key role in cancer progression. Establishing the role of physiological stem cells in malignant disease could eventually be translated into approaches to surveillance of these cells in circulation for cancer prognosis and their targeting for cancer therapy. Finding out whether ASC are the key component of WAT that is activated upon obesity treatment and engages in tumor vasculogenesis is of detrimental importance. Proving or disproving ASC as a functional link between cancer and obesity, and/or as a potential therapeutic target, is essential for strategizing obesity management. If our hypothesis that WAT-derived adult stem cells directly promote tumor growth in vivo is confirmed, the understanding of cancer risk factors and approaches to breast cancer therapy in obese patients will have to be re-evaluated. It is possible that obesity therapy in breast cancer patients may accelerate tumor growth through ASC mobilization, however, introducing a combination ASC inactivation, prototyped by our work, may overcome this complication. In the future, anti-ASC therapy could become a cancer treatment complementary to drugs directed at tumors.
Lay Abstract:
Obesity, manifested by overgrowth of white fat (adipose) tissue, a widespread problem among middle-aged women, has been associated with advanced progression of breast cancer. The mechanism of obesity influence on cancer is not understood. It has been proposed that adipose tissue directly promotes cancer. The study hypothesis: According to our theory, adipose tissue may influence cancer progression through its effect on formation of new blood vessels, the process necessary for expansion of tumor mass. While the involvement of circulating vascular progenitors in tumor vasculogenesis, and their cancer-stimulatory effect, has been demonstrated, the origin of these cells has remained controversial. Here, we propose a novel hypothesis, according to which tumor vasculogenesis relies on adult adipose stem cells (ASC), an abundant population of white fat stromal cells. Because tumors secrete various chemokines (molecules attracting stem cells), it is possible that ASC of obese patients become mobilized and are recruited as a source of vascular precursors for tumor blood vessels. To explore the role of adipose-derived stem cells in promoting breast cancer, we will use patient blood samples and mouse tumor models for several critical experiments that will investigate whether ASC are shed into circulation by pathologically overgrown fat tissue and hijacked by tumors to promote vasculogenesis. By quantifying stem cell content in systemic circulation, we will explore whether ASC are mobilized from fat tissue of patients in response to pathological obesity and breast tumor growth. An experimental approach to reduce body fat content developed by our group (Nature Medicine 2004, 10:625-32) will provide a unique opportunity to assess the influence of adipose tissue on cancer independently from environmental factors. We will test whether such ?molecular liposuction? can change the course of breast caner progression in the mouse model. The tumor response to white fat mass reduction will be correlated with the changes in adipose stem cell circulation. In case if viable ASC are found to be mobilized by obesity reversal and associate with enhanced growth of tumors, our hypothesis will be confirmed. As the final aim of our study, we propose to develop approaches to ablating ASC through peptides targeting their differentially expressed cell surface receptors. Advancing understanding of breast cancer / importance of the research to patients: As a result of this study, the importance of white fat-associated factors for breast cancer progression will be realized. Whether our hypothesis is confirmed or not, as a result of this project, ASC will be better understood as a factor implicated in the pathology of obesity and cancer. In addition, our work will advance the field of basic stem cell biology. There are currently no markers available that would distinguish ASC from adult mesenchymal cells residing in other organs. Identification of ASC markers proposed here will lead to better understanding of the relationship between different types of adult stem cells and of chemotactic gradients controlling their mobilization and tumor homing. Our studies will shift the paradigms in the biology of obesity and cancer, thus setting new directions for subsequent clinical research, and may establish a basis for the development of new approaches to targeting stem cells for therapeutic purposes. Assigning the role for the ASC, or absence of such, in breast cancer progression is critical for strategizing cancer treatment, as it might be realized that obesity therapy in patients could be harmful, rather than beneficial, without a combination measure to inactivate the released ASC. In the future, depletion of adipose vascular progenitor cell pool could become an approach to cancer treatment and possibly a measure for the suppression of breast cancer progression. In addition, our study will help to address the safety of adult stem cells currently being investigated in various pre-clinical trials for potential therapeutic applications in breast cancer patients.
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Here's the Defensive side of my Importance of Positions post. Note: This is based on a 4-3 defence.
1. Middle Linebacker
This was a tough call but in the end, the MLB wins because it acts as the QB of the Defence. They provide the leadership and all-round qualities that are vital on the defensive side of the ball. A good MLB can do everything- they can blitz the QB, cover the middle of the field and, to some most importantly, stop the run. The RB's worst enemy is the MLB as they protect the middle of the field and also have the range to pull across to the sidelines.
A weak MLB doesn't have the effect of a weak QB however. Other positions can make up for the lack of a MLB. DE's provide the rush, DT's stop the run and DB's cover the pass plus the OLB's can do everything a MLB can. While this gap can be covered, it still does leave a hole in your defence which needs to plugged at some time. Another knock on the MLB position is that few MLB's can do all the things I've outlined. Most are just dominent rushers and lack coverage skills. In the end though, a MLB can provide the everything your defence needs.
Do the Lions have a good MLB?- No.
2. Defensive Ends
The Defensive End's importance comes from the fact that he is the biggest problem for a QB, the most important offensive player. A good DE can get to the QB cutting his decision-making time down as well as providing sacks which brings offensive drives to a halt. Good DE's can also make stops on the RB, preventing rushes on their egde.
A weak DE provides the exact opposite of a strong one. No pressure leads to lots of time for a QB to make a decision and good lanes for a RB. This puts significant pressure on the secondary leading to poor perfomance by the whole defence.
Do the Lions have good DE's?- For the most part, White has been a solid veteren and Avril appears to have lots of potential.
3. Cornerbacks
Corner's have a vital job on the defence but are somewhat isolated. Corners mostly have one on one battles with their opposing WR. A good CB does bring a lot to a team though. As someone like Deon Sanders proved, being a dominent corner can completely take a receiver out of the game and prevent a QB from throwing in your area of the field. If a corner can provide such an advantage, the defence goes a long way to being successful. A good Corner can also force turnovers via interceptions which, if athletic enough, can turn into TDs.
A weak CB can lead to easy TDs for the offense, making decent WR's get open easier and giving QB's simple options to throw to. Having weak CB's on your team is a major disadvantage and you won't get to far without them, unless you have brilliance in other areas.
Do the Lions have good CB's?- Not right now. Buchanon was a good FA pick-up but Henry is old and better off as a Safety.
4. Defensive Tackles
Defensive Tackles provide the biggest presence on the field for the defence. Their size is used to plug running lanes and get as much penetration into the backfield as possible. A good DT can completely disrupt an Offensive Line and collapse the pocket keeping the QB on the move as well as limiting the Running backs gaps, preventing large runs. But a DT can do alot more for others, a strong DT can require a double team of blocker's to subdue leaving LB's holes to blitz through.
On the flip side, a weak DT will not be able to prevent a dominent push from the Offensive line on run plays and will provide zero support on blitzs. The biggest problem however is that poor DT's negatively affect LB effectiveness and DE effectiveness. A team without good DT's is a team with a big hole, but the hole can be covered with good coverage and good schemes.
Do the Lions have good DT's?- Not really, Grady Jackson is a stop gap and Darby isn't very good at all.
5. Outside Linebackers
Outside Linebacker's are something of a mixture between DEs and CBs. Most OLB's are used as specialists. Some are pass rusher's who are virtually undersized DE's while other's are good at coverage and are like big Corners. Their importance comes from being able to be used in a multitude of situations and in an all-round compacity like a MLB. However, some OLB's are not on the field all the time with many being taken of on pass plays for DB's. Good OLB's though can provide lots of sacks, lots of tackles and a couple of INTs.
Weak OLB's don't provide as much of a problem as poor MLB's do. Like I said before, many of them are specialist's who provide an extra punch. They can't rush like a DE or cover like a corner. In the end, a weak OLB has the least effect on the defence since they can be substituted out through diffferent formations.
Do the Lions have good OLB's- Yes. Sims is still young and still has upside while Peterson, a new FA pick-up, has great pass rushing capabilities and good coeverage skills.
6. Safeties
Safeties are a position that have no real specific role. They are mainly used to support the CB's and provide extra help in the run but do not specific cover any one position nor do they specifically cover the run. They are 'Safeties', help for a certain part of the Defence. A good Safety does bring a lot though. Most are actually playmakers for the defence with some being slight guys who have good hands and can make picks while some are bigger lads that prefer to intimidate with big hits. Offence's take notice of a good Safety and are always on the lookout for them since they play all over the field.
The reason I consider this the least important position on defence is because Safeties provide nothing crucial for the defence. A weak Safety doesn't require another position to step up it's game, it just means that the Defence won't get any extra help in coverage or the run. It doesn't mean you won't feel the lack of a Safety, it just means you'll feel it less.
Do the Lions have good S's- Debatable. Bullocks has showed ability at times and Alexander hasn't had decent time on the field. We shall see.
Some of you maybe asking, "What about the Kicker or the Punter?". Well, they are important positions but because they play such little amounts of time on the field, their importance is dwindled. A good K or a good P should not be underestimated.


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There are plenty of events taking place throughout central Virginia on Thursday, July 4. For a list of some of the many ways you can celebrate Independence Day, see below:
Crozet's Independence Day Parade & Celebration – July 6, parade at 4 p.m., festivities from 5 p.m. – 9 p.m. after the parade. Balloon rides, live music, food, crafts and an antique car show. Click here for more information.
Charlottesville's Patriotism in the Park – July 4, gates open at 6 p.m. Family-friendly event with food, music, games, and a fireworks display. For more information, click here.
Earlysville Fourth of July Parade – The annual parade begins at 1 p.m. on July 4. The parade begins at the Earlysville Post Office and ends at the Union Church.
Independence Day at Graves Mountain – July 4 from 4 p.m. – 9 p.m. at Graves Mountain Lodge in Madison County.
Independence Day 5K Run- July 4 from 7:30 a.m. to 9:30 a.m. at Forrest Lakes North. Sponsored by the Kiwanis Club of Charlottesville and the Charlottesville Track Club. Benefits Camp Holiday Trails. For more information, click here.
Lake Monticello Spirit Run – July 4 at 7 a.m. at Bunker Park. Late registration deadline is 6:15 a.m. on July 4. For more information, click here.
Louisa Fireman's Parade – July 4 at 7 p.m. Free of charge. For more information, click here.
Naturalization Ceremony - July 4 at Monticello. Dave Matthews of the Dave Matthews Band will speak. Tickets are currently sold out. Begins at 9 a.m. For a live stream of the speech and event, click here.
Nelson County Fourth of July Bike Parade- July 4 on Front Street and Main Street in Lovingston. 10 .m. signup, 11 a.m. parade. Free of charge. Click here for more information.
Scottsville 4th of July Celebration - July 4, fireworks at 9:30 p.m. Free of charge. For more information, click here.
Standardsville Fourth of July Parade – July 4 from 10 a.m. to 4 p.m. The parade goes down Main Street and ends with a patriotic program and a reading of the Declaration of Independence. For more information, click here.
Wintergreen 4th of July Jubilee - From July 1 - 7 p.m. at Wintergreen Resort. Craft fair to take place July 4 and 5. All ages welcome. For more information, click here.
Valley Fourth - July 4, 8:30 a.m. - 9:30 p.m. in downtown Harrisonburg. Activities include puppet shows for kids and "Beers N' Cheers" for adults. Click here for more information.
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Mamba Micro Pro, our popular high performance Micro controller, just got a new partner - the amazing new 0808 4 pole brushless sensorless 20mm motor!
Castle invented 1/18th scale brushless, and now we are raising the bar. Speed controls are only as good as their components. Castle uses only the latest and best. These aren't always the least expensive. We can tell the difference and we are sure you will too.
FETS are the little black things that are the heart and soul of all ESCs. FETS have gotten better, just like memory chips and digital cameras. FET capacities are going up, so should ESC performance. That's the story behind Mamba Micro Pro. Thousands of drivers around the world have enjoyed the Mamba-25, now you can have more amp capacity just because the FETS have improved. Why stop there? When you design and build your own products, you don't have to settle for tired compromises. Castle took the better components and made them work together in a better manner to lower resistance – resistance results in heat, heat limits controllers' power. Castle has designed the circuit boards in a manner to reduce resistance and has added a highly efficient heat sink to help the controller keep it's cool. Mamba Micro Pro is priced the same as the old Mamba-25, yet it offers up to twice the performance. Programming Options Just like the original Mamba-25, the following Mamba Micro Pro settings can be changed with the transmitter:
The Mamba Micro Pro ESC is Castle Link™ compatible too – drivers can use their Castle Link and a Windows PC to tune and tweak additonal settings, such as:
Mini Size, Massive Power. Castle's 0808 series motors may resemble other motors on the market, but that's where the similarities end. They utilize the same 4 pole technology Castle uses to toss around 15 pound monster trucks like rag dolls and wheelie 30 pound Bajas on demand. With the increased efficiency and torque gained from a 4 pole design they will take just about anything the user can throw at them. Just imagine what this little 20mm powerhouse is capable of. They're a mini's worst nightmare…and the competition's. The 0808 series motors are intended for on-road and off-road applications running up to 3S LiPo and weighing in at up to 2.5lbs. Castle offers these motors with both of their race proven Micro ESCs to suit all applications. For 2WD and lighter 4WD vehicles (<1.5lbs) Castle recommends the Sidewinder Micro ESC, and for those with a bit beefier 4WD vehicle (>1.5lbs) they suggest the Mamba Micro Pro ESC.
Specifications: Cells: 2-3s LiPo / 4-12 NiCad/NiMH Continuous: More than you can handle! Resistance: 0.045 ohms Brake: Proportional Reversible: Yes - with lockout Low Voltage Cutoff: Programmable Size: 1.5 "L x 1.1" W x 0.6" H Weight w/wires: 1 oz (28.35 g) Connector Type: Universal Applications: 1/18 2wd & 4wd greater than 1.5 pounds
0808 Motor Specifications: kV: 5300kV Maximum Input voltage: 2S LiPo or 6 NiMH cells Maximum Operating Temperature: 180° (82° C) Connectors: 3.5mm gold connectors Length: 1.5" (38mm) Diameter: 0.79" (20mm) Shaft: 0.08" (2mm) Weight: 1.8 oz (50g)


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A Dudley man has been arrested and charged with Felony Breaking and Entering and Felony Larceny and Possession of stolen goods.
The Wayne County Sheriff's Office says as the result of an investigation into the breaking and entering of a home of Purple Iris Drive in Pikeville back in August 2013, Andrew Johnathan Weaver, 18, of Dudley, has been arrested.
Some of the stolen property has been recovered. The investigation is continuing on this and other cases in the area.
Weaver is being held under a $20,000 bond.
1205 Front St., Raleigh N.C., 27609
Telephone: 919.836.1717
Fax: 919.836.1687
Email: email@example.com


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...for highlighting what a truly awesome place CGB has turned out to be. Thanks Avinash, CBKWit, Hydro, Rags, Twist, Fever, Berkelium, Danzig, and everyone else for making this a great place for an open, fun, lighthearted, argument-filled, hilarious way to discuss Cal sports. It makes the workdays go quickly, makes me question my assumptions about football and I have learned more about the game from CGB than I could read in any other source.
I'm glad you all value free speech and contrasting viewpoints as much as you do, because we've all seen what the opposite is like. Thank fuck I chose Cal.
Thanks again guys!


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Imagine being a young child, and finding out your younger brother has an illness that could change not only his, but your entire family's lives forever.
Crystal Rivera didn't just imagine it, she is living it. The 13-year-old Jefferson Township eighth grader has written a fiction book based her experiences, and part of the money she makes from the book will go to the Juvenile Diabetes Research Foundation (JDRF).
The book, entitled "Diary of a Life Less Sweet," is a fictional diary written by the main character Jade Bluefeather, who has received the news that her sibling has been diagnosed with diabetes. Rivera's younger brother, who is now eight, received that same diagnosis at the age of three.
"I really wrote this book to help other kids who were in the same situation as me," Rivera said. "I remember having so many questions, and thinking, 'am I the only one going through this?'" she said. "I know there are other kids who are in a stage where they can't accept it. Those are the kids I want to help.
"It was very hard to get into the habit of how to take care of him," Rivera said. "Things are back to normal now, but it was hard for a while."
The book includes a listing of information for parents, caregivers and educators.
It took Rivera about 18 months to write the book, which will be officially released at a launch party at Sparta Books on Oct. 15 at 6 p.m.
The book can be preordered now at www.amazon.com or be purchased at Barnes and Noble on or after Oct. 15. In addition, Rivera and her family will be selling books at diabetes walks, one on Oct. 20 at Liberty State Park and another on Oct. 21 at Rutgers University.
Rivera said there is another book in her future, continuing on the theme of helping a sibling.
"I want to continue the story of this book, but it will have a different feel to it, too," she said. "Ever since I was little I've loved to write, and I can write stories for hours, so I'm looking forward to starting the next book.
She said she plans on having it ready in about another 18 months.


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This is your Italian course. This is your Italian course on WordPress.Posted: August 31, 2007 Filed under: ocw | Tags: uvu 1 Comment
Some day I'll get tired of admitting how far ahead of the pack UMW is.
Today is not that day.
So to paraphrase that guy with the egg…
This is your Italian course:
And this is your Italian course on WordPress:
Click the above image to check out a module a UMW Italian professor put together on the Vespa scooter. In the module you watch some vintage Vespa commercials (in Italian, via YouTube), and answer a series of questions about the Vespa based on the commercials.
How can you not want to take that class?
Jim Groom has more details.
A meager startPosted: August 30, 2007 Filed under: Uncategorized 2 Comments
OK, we're not godlike. We ain't Jim Groom.
But we are launching our own WordPress MU intitiative: KeeneWeb.
Our particular angle is going to be less academic, and more creating community on campus, community outreach, and (hopefully) getting some tradmed attention. We have some really talented people on our campus, it's just hard for the outside world to see them. I hope this will change that.
As far as rollout tactics: we're blessed (and yes, "blessed" is probably not an exaggeration) with a provost who gets it, and wants to use a blog to communicate the decisions, trends, and issues that arise in the course of his day. So that gets us to blog as publication. Somebody's going to read that.
Then the hard part: blog as conversation. The only arrow I have in my quiver here, at least to start, is intense personal lobbying of those on campus that might want to get on KeeneWeb and start replying to what the provost writes in his own blog.
But I can be a tireless lobbyist. So perhaps this will work.
Putting together a Web 1.0 website was a relatively set process. You did the paper prototype. You got buy-in. You made up three designs; they picked one. You chopped, diced, wrote, and implemented. You rolled up. You rolled out.
Putting together a Web 2.0 site is much harder. It's more like starting a fire. You rub sticks together or strike the flint, you get a spark and try to fan it. You curse, and repeat. But when it takes off, it can really take off.
I'll let you all know how it goes.
The Parable of the ThingamajigPosted: August 29, 2007 Filed under: ocw | Tags: uvu 5 Comments
We are reaching the end of our evaluation process here on my eportfolio committee. So in a month of impassioned pleas, I hope y'all forgive me one more. This is the last push.
But I want to do it this time by telling a story.
I want us to pretend it is 1985, and we are considering two competing products for the library. Let's say that the need is to teach students how to do research circa 1985, and we've decided to spend some money on a product to do that. The plan is to develop a "research curriculum†and to get a tool that helps us better understand students' research ability.One product is called "Thingamajig†and is billed as a replacement for the NYT Index, ERIC, Dialog, and the card catalog. It replaces the Library of Congress system with its own "superior systemâ€, and collates material from multiple subject indexes into its own aggregate database. It has maybe a tenth of the resources available in the library as a whole, but they are well arranged.
In order to do research students log into this tool and use the special Thingamajig™ search tool. Then they give the Thingamajig call numbers to the librarian, etc. And because all their work is logged in the Thingamajig system, we can very easily assess whether these students are starting to get the hang of "research thinking†– Thingamajig can log and score everything done inside of it.
The other product, which we'll call ResearchRank, just gives some standard ways of assessing student work and pumping out reports. For the actual work, it lets students use the same things they would use outside of the institution: The NYT index, ERIC, Dialog, the card catalog, etc.
In fact, as new resources become available for doing research, ResearchRank doesn't care – if the professor can understand how the student is using them, he can assess them.
Which is the better product? Which serves the student better?
All of these eportfolio template products we've looked at exist in a Thingamajig mindset. Rather than let students use tools that have a broad application outside the boundaries of our college
, they push the student to think of eportfolios as dependent on
institution-specific technology. They keep the student in an unempowered mindset. They force the student to see technology in the wrong way.
To return to our example, imagine it's 1987 and you're a professor hiring for an assistantship. You have to chose between two students.
The first student comes in. And when talking about research they tell you how great they are at research – they are, after all, proficient in Thingamajig. They tell you how they used the specialized undergraduate templates to do research in Thingamajig. Are you familiar, for example, with the "Essay Research Template for Political Themes #5� They did an excellent project using that.
The next student comes in and tells you about subject indexes, the problems of restricted vocabulary, how much they hate the quirks of ERIC, and how low they'll get a result set on Dialog before they print the list. They tell you a neat system they devised using colored post-its to keep track of where quotes came from. And they tell you about the time it failed and they ended up citing Richard DREYFUSS on particle physics.
You'd choose the second student in a heartbeat. Sure, maybe Dialog rolls out a new version in 6 months, and those skills are irrelevant – but the second student has demonstrated an ability to solve real world problems with real world tools. They understand how to interact with technology – technology extends their will rather than limiting or defining it. And because they have to construct their own environment, they don't confuse the process of research with the parameters of some school-bought tool.
You'd choose the second student. So would I. And we'd be absolutely right to do so.
The real world tools of reflection today are numerous, but they are not in TaskStream, or ePortaro. They are wikis, blogs, video-sharing sites, Flickr, del.icio.us, etc. We can show students how to use these tools to better understand and represent their experience.
Or we can buy them a Thingamajig.
I really think that's the choice we're looking at here.
Announcing the Learning 2.0 Pecha Kucha ContestPosted: August 28, 2007 Filed under: ocw 4 Comments
Heard of Pecha-Kucha? It's poetry slam for the design crowd. Haiku for the business world.
It's the solution to Death by Powerpoint. Here's the rules:
- Each pecha-kucha participant delivers a PowerPoint presentation
- Each presentation must comprise of 20 slides, no more, no less
- Each slide must be displayed for exactly 20 seconds
- Consequently, each presentation is exactly 6 minutes and 40 seconds long
(h/t Downes)Â
Now what I would propose is this — anyone reading this post
- Make a Pecha Kucha entry about some aspect of Learning 2.0
- Post it on slideshare or youtube or whatever…
- Tag it on del.icio.us, etc. as PK_Learning2.0
 And let the games begin. I know it would be a lot cooler to get in a room with some gin and tonics and do this, but baby steps, right?
The SmallWonder arrivesPosted: August 22, 2007 Filed under: Uncategorized 2 Comments
We want to go guerrilla video over here, and inspired by the Stanford ePortfolio crowd, we got a couple of SmallWonder cameras from TigerDirect. The idea is that they are less intrusive than a traditional camera, more portable, and easier to use, and that sets the video threshold to a level where people are more likely to grab them on impulse to film something.
We'll see. So far I've been really impressed with the ease of use, and I'm pretty certain I will be buying one myself for my political blogging. Maybe tonight, given how much I like this thing so far…
Here's our first test clip:
The college as student/project matchmakerPosted: August 22, 2007 Filed under: ocw 2 Comments
What would happen if instead of encouraging students to build yet another fake bookstore project we had encouraged them to write wikiscanner?
They'd have changed the world, that's what.
What if instead of having statistics students take multiple choice tests on data analysis we had them examine earmarks or deficit spending using ManyEyes?
They'd change the world, that's what.
What would happen if our Modern Language students translated popular foreign blogs into English, or our film production students organized to film every presidential candidate's appearance within 20 miles and post the video on YouTube or Blip.tv? What would happen if our chemistry students went to the Salvation Army Store and bought historical toys to test them for lead, then posted the results?
We do a lot of real world projects at the college I'm at — in fact, it's one of the most admirable facets of the college. We're truly a leader in this regard.
But my belief is we can (and will) will go much further along this road in the coming years.
Why? Because in the old world there was a real cost to real world projects. Very often you were putting students at the helm of something expensive — equipment, time, something. Putting inexperienced students in charge of those resources was at best a risk, and at worst a danger.
And we built our educational system around those parameters. In the manufacturing economy, you had to run students through simulations of work, because failure was EXPENSIVE and publication RARE. Products required expensive investment, equipment, resources. And even more purely intellectual products had physical limits on them:  in the non-networked economy, publication was the privilege of the few, and outlets for one's findings were hard to come by. There wasn't really much of a publication tier for undergraduates.
So, in many cases we waited until people were in graduate school or in industry to encourage them to do things with real impact. And we spent our time in college with them preparing them so they wouldn't fail when they eventually did engage with the world-at-large.
There are (and were) exceptions, and many of them. There are stunningly good programs at my college that put students in Art and Architecture and Safety Studies in positions where they do great work, real work, in service to the greater community. And when I see such things, I'm just inspired and proud.
But I'm saying in our net-enabled world, we can make such learning the norm, and not the exception.
The reason why is simple economics. In a networked information economy, failure is cheap. Production is cheap. And if you produce something worthwhile, distribution is free.
Film students don't have to tie up the professional grade camera (at least not for everything) — they can film events on a $100 USB device. Statistics students don't have to pay for database access or tools — there's a wealth of public data out there, all waiting for someone to sift through it. Translation of a foreign blog takes only a student and a computer.
The other day I wrote an application that posts to twitter every time a bill or resolution is passed in the House of Representatives. It took me two hours. It didn't cost a dime.
There are literally thousands of worthwhile projects out there, just waiting for a student to take them on. But students aren't familiar enough with the landscape of real-world needs to know where these opportunities are.
If we want real academic engagement, we have to treat undergraduate education the way we treat our most successful graduate programs. We have to see a major part of our role as pairing interested students with interesting problems. We have to be a bit of a matchmaking service. Because that's how we are best going to help our students change the world.
Giving your students a toolbeltPosted: August 21, 2007 Filed under: Uncategorized 1 Comment
UMW has put together a tools section for incoming freshmen and new faculty. The idea is to present to them six free low-threshold tools which will be their tools of the trade for the years to come.
The tools are:
Firefox, WordPress, del.icio.us, Google Docs, Google Reader, and Flickr.
As much as I like to tell people the task of choosing tools never ends, this idea of a standard toolbelt is incredibly powerful, and it's made even more powerful by presenting it to incoming students. While the specific tools chosen here are perhaps replaceable, the technologies represented are not. The key concepts of modern information literacy are all here: tagging, category-based navigation, syndication, conversational media, trackbacks, collaborative workspaces and loosely coupled media.
And it's important for kids to know (and for the college to tell them) that a person who does not understand these concepts is as illiterate today as a person who couldn't operate a card catalog or an subject index years ago.
It's perhaps even more important to tell students that they will meet many challenges in the coming years, but that a good deal of these challenges can be met using these tools. The power is, after all, with them.
At eportfolio workshopPosted: August 16, 2007 Filed under: Uncategorized 1 Comment
I'm at an eportfolio workshop at Stanford. More on that later.
The weather here is beautiful, much milder than in New Hampshire. I had no idea.
On the other hand, there is a "What to do when there's an earthquake" card in my hotel room. So perhaps a mixed bag.
There is no "tech". Get over it.Posted: August 10, 2007 Filed under: Uncategorized | Tags: ocw Leave a comment
Via SmartMobs, regarding our millenials:
"Young people don't see "tech†as a separate entity – it's an organic part of their lives,†said Andrew Davidson, vice president of MTV's VBS International Insight unit.
"Talking to them about the role of technology in their lifestyle would be like talking to kids in the 1980s about the role the park swing or the telephone played in their social lives — it's invisible.â€
The more you get into "tech", the more you realize there's no such thing. As any systems analyst will tell you: there are processes, and some pieces of them are automated and some aren't. Some pieces have hardware components, and some don't. Some storage is on paper, and some on tiny electric switches.
The process is inviting your friends out for a drink. It's not using the telephone in drink invite mode. You don't start out and say I need a product to invite my friends out for beers and optionally gin and tonics. And we don't really worry that the phone is from one vendor, and the cab you take down to the bar is from another.
What we say is — hey, wouldn't it be neat if instead of having to call everybody seperately I could communicate with them all at once? And slowly that process evolves…
What's my point? I suppose it's that from a process standpoint, if we see our personal algorithms as the higher order application, loose coupling has been the norm, more than we realize. And given the worldview of the current crop of kids, we're likely to get back to that. And that's a good and powerful thing.
Progress on loosely coupled assessmentPosted: August 8, 2007 Filed under: Uncategorized | Tags: uvu 1 Comment
So we watched a presentation yesterday by True Outcomes, and of course I had to hold my nose a bit. I come from the "merit badge" school of Roger Schank, that ideally assessments fall into to the category of "Student X can build a fire, and we know that because he built a fire" (or in Schank's case because he completed a case-based simulation of building a fire). Align a curriculum more towards doing and less toward demonstrating "qualities", and a lot of assessment headache goes away. In a doing culture, assessment is healthy, because it maps onto real world goals — can this person solve a real world data import problem using a scripting language? Yes? Great! Merit badge!
But "displays knowledge of data analysis techniques and an understanding of how to automate data import processes"? Mapped onto a one to five value rubric?
That's assessment, and it happens most often when we think the student can't do anything of value.
That said, I loved the True Outcomes presentation. Why? Because it was pure assessment. There was no eportfolio product attached to it (or rather, the presentation product attached to it was so slight as to be insignificant). What's more, the students don't even have to submit into it — there's a simple option called "Observation" (as opposed to electronic submission) where professors can assess student work outside the program. So if students want to do an eportfolio project in WordPress or Google Documents they could conceivably do it, and just have the professor save a copy of the artifact to local storage somewhere. They want to videoconference it or Skype it in? Again, not a problem. The system doesn't care.
The point here is that with assessment loosely coupled, the process can be fluid, and defined by the individual needs of the professors. Because the portfolios can be based on an unconstrained worldware approach, professors sold on a Web 2.0 approach are free to push the pedagogical envelope, and let students do things in Blogger, WordPress, or YouTube.  Professors who don't want to invest time in those things can tell the students to do something or other in MSWord.Â
By not tying the assessment product to the pedagogy, you make sure that you are not hindering your more forward-thinking professors. And you guarantee that as technology evolves outside the college that you'll automatically benefit from those advances — whether or not you buy the most recent vendor upgrade.
In short, you make evolution possible.
Anyway, I'm very happy about this development. If your institution is currently looking at eportfolio/assessment solutions, I'd suggest that you consider looking at True Outcomes, and put to rest the assessment bit. Then, with the vendor no longer hanging about, suggest a worldware approach to eportfolios and the like.
I'll keep you all updated on how that goes here.


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Archive for November, 2011
The Best and Only Worthwhile Analysis I've Seen on this European Economic Crisis
Posted by chicagosean on November 28th, 2011 at 8:00 pm, Comments: 0
Share on StockTwits It seems every day for months we U.S. traders and investors have been waking up to large overnight moves – in both […]
Social Media & Finance: Best Practices, Compliance, and Personal Hygiene.
Posted by chicagosean on November 6th, 2011 at 10:25 pm, Comments: 0
Share on StockTwits My pink-shirted friend Mike Wilkins (aka @ilkandcookies) recently moderated a panel on Social Media in Finance which I was asked to participate […]
Sean McLaughlin - Editorial, Curation, & Investor Relations Solutions at StockTwits. Also, former Member of the Chicago Board of Trade who trades his own account in Boulder, Colorado. More »
Recent Posts
- A Losing Trader's Response To Jesse Livermore's "21 Rules"
- The "Stock Market" Does Not Owe You Anything
- Simple. But Smart?
- Early Candidates for 2014 Asshat of the Year Award: Hero Edition
- Dealing With Performance Anxiety
- Developing The Right Mindset
- Anecdotal Bullish/Bearish Sentiment on StockTwits
- Why I Love StockTwits: Community
- Do You Factor "Luck" Into Your Strategic Process?
- Stocktoberfest Late-Night


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A crash on Highway 18 sent one person to the hospital late Saturday afternoon.The accident happened at the Springridge Road intersection, just before 5 p.m.
The crash caused the green pick-up involved to face the wrong direction. A black SUV was also involved.
At least one person was taken to the hospital by AMR. We have no word on their condition at this time.
One lane of traffic was closed down while crews cleared the scene.
MS State troopers are investigating the accident.
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Doody's Review ServiceReviewer: Steven N. Hart, BS (University of Kansas Medical Center)
Description: This book is a start-to-finish approach to incorporating genomic data into the drug discovery pipeline.
Purpose: The purpose is to introduce many novel strategies, technologies, and toolboxes to aid researchers and industry professionals in progressing toward personalized medicine. More specifically, this book addresses three major components essential for personalized medicine: biomarker discovery, toxicogenomics, and pharmacogenomics with a particular emphasis on incorporating these platforms during early stages of drug design. The rationale for this approach is to stratify patient populations to identify subjects at risk of clinically significant toxicity and nonresponders to allow for safer, more effective, and more rapid drug discovery. These objectives are well defined and clearly addressed.
Audience: The book is intended to be of interest to academics, biologists in the pharmaceutical industry, and regulatory personnel who are in a position to appreciate the complexity of genomics and the wealth of useful information that it can provide. The idea is that these professionals will incorporate genomic data mining into drug discovery platforms. Many topics in this book will be of particular interest and familiarity to only one of these subgroups at a time, whereas those inexperienced in a particular area may find themselves being introduced to new concepts, but in a clear, easy to follow manner.
Features: In the book's nine chapters, readers are exposed to all relevant aspects of the strategies for and the implications of genomics in drug discovery and development. There is a strong and necessary emphasis on toxicogenomics, which serves as a major bottleneck in the drug development pipeline. Among others topics, gene expression array technology, data analysis, and how to make data publicly accessible in genomics databases - a requirement for all government funded genomics studies - are thoroughly covered.
Assessment: This book covers many of the relevant aspects of incorporating genomics into the standard drug discovery workflow. Of particular interest to me was the chapter on genomics technologies as tools in drug discovery. As an academic involved in genomics and pharmacology, I use many of the tools in this book frequently. The authors address many of the pitfalls associated with these technologies and also identify several key computational biology tools (such as databases) essential for the interpretation of genomics in drug discovery. The book also introduced me to the regulatory implications of how to transition genomics from the bench to bedside, a viewpoint that is sometimes lost in academia. Overall, it provides excellent, up-to-date coverage of the application of genomics in drug development.


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When Your Faith is Misplaced
Once a year it is my privilege to get together with my dear friend Deacon Charles Barnhart of the Evangelical Lutheran Church in America (ELCA). Charlie serves as the chaplain for the Cumberland Valley Volunteer Firefighter's Association (CVVFA) and...
Once a year it is my privilege to get together with my dear friend Deacon Charles Barnhart of the Evangelical Lutheran Church in America (ELCA). Charlie serves as the chaplain for the Cumberland Valley Volunteer Firefighter's Association (CVVFA) and over the course of the past 10 years he and I have spent a great deal of time sharing ideas as well as sharing our love for the Lord. Let me suggest that over time I have learned that Chaplain Charlie has a special way of stimulating my thought processes.
We spent a great deal of time at the CVVFA 110th Annual Meeting in McConnellsburg, PA catching up on life in general. I spoke of my daughter's wedding engagement and my son's ordination as a priest. Charlie shared the fact that his Bishop in the Lutheran Church granted him the ability to carry out all of the necessary services which a pastor is allowed to perform. We had a good time catching up on life in general and our church work in specific. He then asked me to pay close attention to his sermon during our annual memorial service which we hold to remember association members who have passed away during the past year. He thought I might find it interesting.
The first lesson, which was from the Book of Ecclesiastes, set the tone of the day for me. It covered the essence of life as we know it today. It was the verse which tells us that for everything there is a season. There is a time to be born and a time to die. Let me take it in a slightly different direction my friends. Let me suggest that there is a time to lead and a time to follow. There is a time to stay the same and a time to change. The key for you and me is to make sure we are doing the right thing at the right moment.
My friends, is it not possible that when we fail to note the changing seasons around us, that we begin to go in the wrong direction? I am not referring to the obvious changes like day to night, summer to fall, and fall to winter. No, I am referring to such things as the way in which people seemingly age and die and the way that new people come and older folks step aside. In addition I am referring to the societal changes which creep up on us each and every day. But there are certain rock solid precepts that we must always adhere to.
The famous hymn, "Amazing Grace" served as the foundation for Chaplain Charlies' message to us. It served as a solid foundation for his comments on grace, mercy, and peace. One of the major points of his presentation suggested that all of our success and good fortune in life came about as a result of the Lord's Grace. More importantly, he equated the concept of grace with love. He noted that each of us turns out to be what we are because of the Lord's love. How can a person go wrong if they meet life with the love of the Lord as a core value?
Sadly, my friends think of how many in the secular world scoff at you and me when we speak of our faith and our love for the Lord. The rules are really simple. My first priority is to live by the Golden Rule. I have often felt that if I was busy treating others as I would ask them to treat me, how could I be headed in the wrong direction. I have placed my faith in others many, many times, and rare has been the case when my faith was not met in like kind.
How often have I shared with you the message that you need to have the respect and support of your fellow travelers in your journey to be an effective leader? As one who has served in a variety of leader and follower positions, I feel comfortable in stating that one of the important things a leader must do is protect and defend their people from unnecessary and unwarranted criticism and interference.
Back in the day when I was serving as a chief officer in the Newark Fire Department, one of my critical personal goals was always to take care of my guys. Let me assure you that this was never an easy job. It seems as though I was working with and for people whose top-most goal in life was to avoid responsibility and assign blame to others. They never wanted to get any mud on their skirts. My job was to stand up for my guys and take whatever nonsense the front office would send our way.
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Explore Harvard's Nieman network
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Nieman Foundation for Journalism at Harvard: Nieman Reports
Summer 1999
War Crimes, Human Rights and Press Freedom: The Journalist's Job
By Melissa Ludtke, Editor
The Journalist as a Witness to War Crimes
By Ellen Hume
Confronting the Abuses of Human Rights
By John Shattuck
9 Mass Graves: An Excerpt From 'Crimes of War'
By Elizabeth Neuffer
A Serbian Journalist Ponders What Has Been Lost
By Dragan Cicic
An Albanian Newspaper Is Reborn
By Ardian Arifaj
In Yugoslavia, the Consequences of Not Reporting the Truth
By Chris Hedges
The Journalist as Moral Arbiter
By Michael J. Kirkhorn
Penetrating Milosevic's Wall of Silence
By Mark B. Lewis
Reflections of Balkan Journalists
Excerpts From Global Beat
Images and Words From the Balkan Conflict
By David Brauchli
Dealing With the Trauma of Covering War
Excerpts From a Conference
A Ugandan Journalist Is Taken to Court By his Government
By Charles Onyango-Obbo
Watching the Watchdogs
By Wilson Wanene
Chilean Media Work in the Long Shadow of Pinochet
By Mirko Macari
Immigrants Ignite a Media Maelstrom in Greece
By Dimitri Mitropoulos
Reforming Welfare, Reporting on Poverty: The Challenges of Reporting This Story in Various Communities and Other Countries
By Melissa Ludtke, Editor
Constructing the Welfare Story Brick By Brick
By Bill Kovach
The Evolving Coverage of Welfare Reform
By Lynda McDonnell
Welfare Reform and Latinos = Immigration and Cultural Politics
By Joe Rodriguez
Asian-Americans and Welfare Reform
By William Wong
The 'Welfare Queen' Experiment
By Franklin D. Gilliam, Jr.
In the Midst of Poverty, People's Stories are Hard to Tell
By Pat Gish
Why Identify Welfare Recipients or Quote Incorrect Grammar?
Portraying Poverty in the Face of Newsroom Pressures
By Martha Shirk
European Reporters' Views of America's Welfare Reform
By Martin Gehlen
Words & Reflections: 'The Monica Thing' and Other Observations About Journalism
By Melissa Ludtke, Editor
Searching for Facts in a Sea of Speculation
By Richard Harwood
'The Monica Thing'
By John F. Stacks
Blurring the Lines Hurts Journalism
By Jim Lehrer
The Strange Questions Journalists Ask
By Richard L. Fox
Why I Asked Jesse Jackson About the Media
By Adam-Paul Smolak
'The Republic of Entertainment'
By Josh Getlin
Max Frankel's Life and Times
By Jack Nelson
Nieman Notes
Finding Stories of Common Concerns
By Susan E. Reed
Using the Camera to Peer Inside
By Beatriz Terrazas
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Using the Camera to Peer Inside
By Beatriz Terrazas
When I went to Cuba in January 1998 to photograph Pope John Paul II's historic visit, I was seeing a familiar subject—I'd been there with my camera for his visits to Mexico and the United States—but I was capturing images of him and his worshipers in unusual surroundings.
The juxtaposition of communist and Catholic icons gave the events in Cuba a sense of incredulity. From the main press platform at the site of the mass in Havana I could see a full color rendering of Jesus that hung several stories high at the altar. Then, when I looked 90 degrees to my left, the likeness of Che Guevara, also several stories high, looked down upon the crowd. Because of the tight government controls, there were no vendors hawking miters or young people wearing paper masks in his likeness as I'd seen at other papal events. There was only a set of government-approved commemorative stamps for sale.
But the biggest difference for me, as an American journalist, was found in the conversations I had with Cuban people. Some were wistful for the life I am able to live, the freedom I have to travel, and what I can afford to buy. Others wanted to reassure me about the strength of their religious belief despite their government's claim to the contrary. And everywhere I went on the street women approached me to ask for lipsticks or magazines.
The images that stand out for me from this trip are not of the Pope but of the faces of Cubans. Etched in their faces are memories I have of conversations we had, of times when strangers approached me to share their stories and left me thinking differently about my life and aspects of it that I realized I too often take for granted.
Beatriz Terrazas is a 1999 Nieman Fellow and a staff photographer for The Dallas Morning News. Photo courtesy of The Dallas Morning News.
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After a night of near-perfect defensive anticipation, a quick collision in the defensive backfield gave Ole Miss their first offensive touchdown of the night — and, when you think about it, their first impressive pass play of the evening. About time.
Jevan Snead found Rebels wideout Markieth Summers wide open behind the Gamecock defense after safety Zo Winfield got tangled up with teammate Chris Culliver. Summers waltzed into the end zone for an easy score. The challenge now: Escaping Columbia alive, and with that No. 4 ranking intact.


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2012-13 Sophomore Season:Appeared in all 40 games this season for the Gophers recorded 20 points (four goals, 16 assists) this season after being held without a point as a freshman recorded his first goal as a Gopher in a 5-1 victory over the Spartans of Michigan State (10-12) recorded a pair of assists against the Spartans (10-13) tallied his second goal of the season to give the Gophers the lead against Nebraska Omaha (11/30) assisted on Ryan Reilly's first collegiate goal in the second period off a Mariucci Classic game vs. Air Force (12/29) collected a point for the second-straight day to help the Gophers past the Eagles of Boston College to the Mariucci Classic title (12/30) extended his point streak to three games with a goal against Notre Dame (1/8) tallied a point for the fourth-straight game with an assist against Alaska Anchorage (1/11) recorded the secondary assist on Jake Parenteau's first goal of the season against North Dakota (1/19) recorded an assist on Seth Ambroz's goal during the Hockey City Classic in Chicago (2/17) recorded the primary assist on a Nick Bjugstad power-play goal at Bemidji State (3/8) notched a two-point night, with a goal and an assist, in a 5-1 victory at Bemidji State to close out the regular season (3/9) assisted on Kyle Rau's game-winning goal in game one of the WCHA playoff series against Bemidji State (3/15).
2011-12 Freshman Season: Skated in 11 games made his collegiate debut against Sacred Heart (10/8) won eight of 10 faceoffs at St. Cloud State (1/28).
International: Played on the U.S. Under-18 Select Team at the 2009 Ivan Hlinka Memorial in Piestany, Slovakia shared the team lead in scoring with Gopher teammate Sam Warning by putting up two goals and two assists in three games led team with a +5 rating played in four games and recorded an assist for the second-place U.S. Under-17 Select Team at the 2008 Five Nations Tournament in Prievidza, Slovakia.
High School: Spent 2010-11 playing for the Sioux Falls Stampede of the USHL played under head coach Kevin Hartzell on the same team as fellow Gopher Kyle Rau (Rau joined the team after the high school season ended) led the Stampede in scoring during the regular season with 44 points played prep hockey for St. Thomas Academy under Greg Vannelli and former Gopher Tom Vannelli was a finalist for the Minnesota Mr. Hockey Award and was a first team all-state selection in 2009-10 honorable mention for the all-state hockey team in 2008-09 three-time All-Classic Suburban Conference selection helped lead Cadets to a Class A state championship in 2007-08 Star Tribune Prep Athlete of the Week for the week of 3/11/08 and Pioneer Press Athlete of the Week for the week of 12/15/09 drafted in the seventh round of the 2010 NHL Draft by the Buffalo Sabres.
Personal: Major is undeclared hobbies include wakeboarding and golfing most memorable sports thrill was winning the Class A Minnesota High School State tournament son of Tracy Isackson born January 20, 1992.
More Headlines
8/28/2014Parenteau Joins Orlando Solar Bears
8/18/2014Rogge Joins Gopher Hockey Team
08/07/2014Kyle Rau Twitter Q&A Rewind
08/04/2014Holl Signs with Rockford IceHogs
07/29/2014B1G Schedule and Notre Dame Updates


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Tim Aspinwall focuses his practice on healthcare and administrative litigation, including administrative hearings, writs and appeals.
He is co-author of a book California Administrative Law: Adjudication and Separation of Powers, forthcoming Spring 2014, Rutter Group.
Mr. Aspinwall represents healthcare professionals and institutional providers in their defense against administrative actions brought by state agencies and licensing boards. His individual clients include physicians, nurses, dentists, pharmacists, midwives, social workers, chiropractors, and all other healthcare professionals. Mr. Aspinwall also represents individuals and institutional clients in medical staff peer review, and Medi-Cal and Medicare audits.
Mr. Aspinwall also represents licensed professionals before the Department of Real Estate, State Contractors License Board, Department of Insurance, Board of Professional Engineers and Land Surveyors, and most other professionals licensed and regulated by the State.
In 2010-2013 Mr. Aspinwall served as chair of the American Bar Association Health and Human Service Committee of the Administrative Law section. In 2007 – 2010, Mr. Aspinwall served on the California State Bar Lawyers Assistance Program. In 2000 – 2007, Mr. Aspinwall served as a member of the Sutter Health Central Area Institutional Review Committee.
Represent licensed professionals in hearings before the Office of Administrative Hearings, petitions for writ of mandate, and appeals.
Represent medical staffs and physicians in medical staff peer review and disciplinary matters, including settlement negotiations and litigation as necessary.
Represent individual and institutional healthcare providers in Medicare and Medi-Cal reimbursement audits and investigations.
Represent individual and institutional healthcare providers in Medicare and Medi-Cal provider status appeals.
J.D., Vanderbilt University Law School, 1986
L.L.M., Loyola University Chicago School of Law, 2000, Institute for Health Law
MacLean Fellow, University of Chicago Center for Clinical Medical Ethics, 1995-1996
M.A., University of Chicago, 1995, Divinity School
B.A., University of Utah, 1983
American Bar Association
California Society for Healthcare Attorneys
California Academy of Attorneys for Health Care Professionals


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And in the area of non-casting...News
January 08, 2003, 10:27 AM
We've been hearing rumors that Cedric Diggory (no casting ever announced), Oliver Wood (Sean Biggerstaff) and Colin Creevey (Hugh Mitchell) will not be in PoA at all - not even in the background. We're checking into these rumors to see what we can confirm but at present, please consider them just that - rumors. It can also be noted that in the latest Sean Biggerstaff interview (here and here), he says he has not " as of yet" signed on for the third HP movie.


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Kumon Reading is a balanced program representing the best documented practices in reading instruction. It covers skills from understanding the sounds that make up words to the summary and critique of complex reading passages. Good writing and speaking skills are fostered as a natural outgrowth of the Kumon Reading curriculum. Kumon students at every level read daily. That alone confers enormous benefits.
Areas covered by Kumon reading include:
Due to inclement weather the Hockessin Center will be closed on Tuesday, 21st Jan 2014. Homework can be picked up fom the bin outside.
Bear Center will be closed on Wed, 22nd Jan 2014. Homework will be available in the bin after 12:00 noon on Thu 23rd Jan 2014.
If you can, swing by and pickup the homework. Take care and be safe.
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These animals and many others await adoption at the Bulloch County Animal Shelter. Please call 764-4529 or visit the shelter Mon. - Fri., 1-5 p.m. or Sat., 10 a.m. - noon. Adoption fees are $35 and include shots, worming, and a coupon for spaying or neutering that is provided by the Humane Society.
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Legal Ethics
Defense Lawyer and Life Coach Accused in Ethics Complaint Cites Lectern Misunderstanding
Posted Nov 16, 2011 11:48 AM CDT
By Debra Cassens Weiss
A well known Minneapolis defense lawyer who touts his services as a life coach says some of the recent ethics allegations against him are due to misunderstandings.
Lawyer Barry Voss is accused in an ethics complaint (PDF) of failing to pay employer withholding taxes, overdrawing his trust account, failing to respond to client inquiries, and keeping referral fees without accounting for the time spent. The Minneapolis Star Tribune and the MinnLawyer Blog covered the allegations.
Voss has represented defendants in several high-profile cases, including the alleged leader of the "Beat-Down Posse" who is awaiting trial on racketeering charges, the Star Tribune says.
Voss tells the Star Tribune that a new accountant is clearing up the tax allegations and he never withheld money from clients. He said some of the complaints against him are due to misunderstandings, such as the time he stood at a lectern with a blank legal pad, leading a client to believe he wasn't doing any work.
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