text:
Staff Blog
Staff Picks
Win Stuff!
Special Sections
News Blog
News Home
City Desk
Cincinnati vs. the World
News Archive
Opinion Home
Politics/Issues Blog
Kathy Y. Wilson
We, as Humans
Worst Week Ever!
On Second Thought
Curmudgeon Notes
The Alternative
Music Home
Music Blog
MidPoint Music Fest
Live Music Events
Spill It
Minimum Gauge
Arts Home
Arts Blog
Art Events
Visual Arts
Curtain Call
The Big Picture
Classical Music
Film Home
Movies Blog
Movie Reviews
Food & Drink Home
Reviews & Features
The Dish
Local Restaurants
Local Happy Hours App
All Blogs
The Morning After
CityBeat Staff Picks
Event Calendar
Music Calendar
Arts Calendar
Submit a Listing
CityBeat Events
Crafts + Drafts
Margarita Madness
Sugar Rush
Camp Guide
Anna Louise Inn
Annual Manual
Answers Issue
Best of Cincinnati
Cool Issue
Drinking Issue
Election Coverage
Fall Arts Preview
Food + Drink Issue
Fringe Festival
Government Shutdown
Green Issue
Love List
MidPoint Music Fest
MPMF Visitors
Summer Guide
Sign Up for Emails
City Desk
Federal Judge Strikes Down Kentucky Gay Marriage Ban
Nick Swartsell
0 Comments · Wednesday, July 9, 2014
A federal judge on July 1 ruled Kentucky's ban on gay marriage is unconstitutional. But same-sex couples in the state can't get marriage licenses just yet.
by Nick Swartsell
07.02.2014 61 days ago
Posted In:
at 08:36 AM |
Morning News and Stuff
Kentucky's gay marriage ban unconstitutional, ticket hike to save historic buildings, Kasich and Brown take an usie
Here at the morning news desk (which is really just my desk, only in the morning), we usually lead off with some local news. But the big story of the moment comes from across the river.Kentucky's gay marriage ban is unconstitutional, a federal judge ruled yesterday. The judge struck down Kentucky's amendment to its state constitution banning same-sex marriages, though he is holding implementation of his ruling until after hearings here in Cincinnati next month. The next showdown over gay marriage in the region comes Aug. 6, when the U.S. 6th Circuit Court of Appeals downtown will hear cases from Ohio, Kentucky and other states about same-sex marriage bans. Hamilton County Commissioner Todd Portune is pitching user fees for events at Music Hall and the Cincinnati Museum Center as a way to raise funds to renovate the historic buildings. He floated the idea in a letter yesterday, where he also indicated he's not sold on the idea of a sales tax hike to pay for the renovation projects. Portune said he's not a flat no on the tax hike but that it will be a tough sell for him without some kind of ticket price increase. The buildings need more than $300 million in repairs. An Indianapolis-based developer working on rehab projects for three iconic historic buildings in Cincinnati is making progress. Core Redevelopment LLC is redeveloping the former School for Creative and Performing Arts building in Pendleton, the Crosley building in Camp Washington and the old Windsor Elementary School in Walnut Hills. The group was just awarded tax credits on the Windsor project, which will contain 44 units of housing. CEO John Watson indicated that he thinks Walnut Hills is on the verge of a "full scale redevelopment" as a neighborhood. The SCPA project is expected to break ground in September and will be home to 142 units. Finally, the group will develop 238 units in the looming white Crosley building, which was built in the 1920s by the Crosley company as a factory for radios and other items. All three projects will be market rate housing. The group expects the 800-square-foot, one bedroom units at the Windsor building will run a little over $800 a month.The city of Middletown is officially dissolving its housing authority after complaints it tried to kick people off Section 8 rolls. The Middletown Public Housing Authority voted unanimously to dissolve itself yesterday. MPHA will shut down by September, turning over 1,662 Section 8 vouchers to Butler and Warren Counties. Miami University of Ohio is the most expensive public university in the country, a new study finds, and Ohio's other public universities are also among the priciest. Miami rings up at a net cost of $24,000 a year after financial aid is considered. As an alum, this makes me wonder if the resale value of their degrees is higher, too. I have one recent-model English/Poli Sci double if any one's interested… rarely used, buyer takes over payments.It's not every day you see your state's Democratic senator take a selfie with your ultra conservative, Republican governor. But Sen. Sherrod Brown and Gov. John Kasich apparently got cozy for the camera yesterday at The Banks while celebrating the new GE deal. Cincinnati, bringing people together.Finally, scientists are working on breeding bald chickens that can withstand the increased heat caused by climate change in regions near the equator. That's... terrifying. I imagine they'll be able to do it, though, since they've already been able to genetically engineer the spicy and extra crispy varieties.
by Nick Swartsell
07.01.2014 62 days ago
Posted In:
at 12:39 PM |
Federal Judge Strikes Down Kentucky Gay Marriage Ban
Next showdown will happen at federal appeals court in Cincinnati
A federal judge today ruled Kentucky's ban on gay marriage is unconstitutional. But same-sex couples in the state can't get marriage licenses just yet. U.S. District Judge John G. Heyburn II ruled that a 2004 amendment to Kentucky's state constitution prohibiting same-sex marriage violates the guarantee of equal protection under the law found in the U.S. constitution. It's another sign that the tide may be turning in the region. The decision comes as a similar ban looks to be in serious legal trouble in Indiana, and just before an August federal court date that will decide questions surrounding the issue in Ohio and other states. Since February last year, federal courts have upheld the right to marry for same-sex couples 19 times.The decision came in response to a challenge to Kentucky's ban by two same-sex couples. Maurice Blanchard and Dominique James were denied a marriage license on Jan. 2013. They were charged with trespassing after refusing to leave the Jefferson County Clerk's office after being turned down for their license. A jury eventually found them guilty, though the two were fined only $1. The two other plaintiffs in the case, Timothy Love and Lawrence Ysunza, applied for a license in February 2013. The two have lived together for 34 years.The plaintiffs and other same-sex couples looking to marry will have to wait a little longer, though. Heyburn has delayed implementation of his decision until after Aug. 6, when a higher court, the 6th Circuit U.S. Court of Appeals, will hear several gay marriage cases from Kentucky, Ohio and two other states. Those cases will be heard in Cincinnati.Heyburn, who in February also ruled that the state must recognize same-sex marriages from other states, rejected Kentucky's reasons for its ban. Lawyers hired by the Kentucky Gov. Steve Beshear argued that traditional marriage helps ensure economic stability and a favorable birth rate in the state. The state's Attorney General Jack Conway refused to defend the law on behalf of the state."These arguments are not those of serious people," Heyburn said in his decision. He said there is "no conceivable, legitimate purpose" for the ban, which keeps same-sex couples in the state from enjoying the economic, social and emotional benefits of marriage. These include tax benefits, the ability to share insurance, the ability to adopt children as a couple and other rights.The ruling continues a wave of recent decisions by federal courts upholding marriage rights for same-sex couples. But there's still uncertainty even as the tide shifts. Most recently, on June 25, a judge struck down Indiana's ban, allowing same-sex couples to immediately apply for marriage licenses. That decision was overturned a few days later on appeal, and couples who married in the three-day window are now waiting for a final decision to see if their marriages are valid in the state's eyes. Currently, 19 states and the District of Columbia allow same-sex marriage.
by Judy George
06.04.2014 89 days ago
Posted In:
City Roots
at 02:00 PM |
City Roots: The Giving Fields
Freestore Foodbank grows fresh produce for people in need
Tucked away on the Ohio River, 10 miles from downtown Cincinnati, lies a quiet farm with long, beautiful rows of nutrient-dense kale, broccoli and lettuce, ripe strawberries and blueberries, bee hives and a magnificent orchard of nearly 400 fruit trees. This idyllic and very productive farm doesn't earn a penny. Welcome to the Giving Fields in Melbourne, Ky., a 10-acre farm operated by the Freestore Foodbank growing fresh produce for people who can't afford to buy food. "The people we feed are at high risk for diabetes and heart disease," says Jennifer Steele, director of community partnerships for the Freestore Foodbank. "We want to serve more fresh fruits and vegetables and fewer highly salted, highly sugared processed foods." Five years ago, less than 10 percent of the food the Freestore distributed was fresh; most was canned or boxed. Now, 40 percent of the Freestore's food is fresh or frozen, Steele says. At the Giving Fields, farm manager Molly Jordan grows produce specifically for the Freestore's food pantry and soup kitchen partners in Northern Kentucky."Our food goes to Northern Kentucky because the need is greater there," Steele says. It's easy to see why, since state laws make fresh food less available to Kentucky charities. In Ohio, the Agricultural Clearance Program sets aside $17 million a year for Ohio farmers to sell surplus or blemished food to food banks. A similar initiative in Kentucky, still in its infancy, allocates only $600,000 for food banks to receive surplus produce annually. At the same time, the number of Kentucky residents who depend on food donations is increasing. The Kentucky Association of Food Banks reported that 620,100 people now rely on food banks, an 84-percent increase from 2006. The Giving Fields harvests fruits and vegetables for 117,000 meals in Northern Kentucky each season. Food pantries and soup kitchens receive the produce the day it is picked. "The Kentucky Department of Agriculture also gives out recipe cards at food pantries so people can learn how to prepare the food we grow," Jordan says. The farm relies on more than 1,000 volunteers — civic organizations, corporate teams, church groups and others — who work there each year. Jordan alternates rows of crops with wide strips of grass so volunteers can move easily throughout the fields. She also cultivates plants in tall wooden beds so people with limited mobility and senior citizens can weed and harvest, too. At 10 acres, the Giving Fields is one of the largest food bank farms in the country, according to Feeding America, a nationwide network of U.S. food banks. The Freestore funds operational costs for the farm, collaborating with Doug and Sheila Bray of Wilder, who own the land, and the UK Cooperative Extension Office. The Giving Fields is now in its fourth growing season. To volunteer at the Giving Fields, call the Freestore Foodbank at 513-482-7557 or email Tawanda Rollins at firstname.lastname@example.com. ON THE CITY ROOTS CALENDAR June 7: Gardening for Pollinators Workshop Honeybees, which are crucial to the production of local fruits and vegetables, are vanishing. Greenacres offers a workshop to learn how to attract butterflies, bumblebees, honeybees and other pollinators to your yard from 10 a.m. to noon at Greenacres Old Church, 8680 Spooky Hollow Road. $15. green-acres.org. June 9: Garden Basics Class Pest control, plant disease, watering and water conservation and other seasonal topics will be reviewed in this class offered by horticulturist Bennett Dowling at the Civic Garden Center from 6-8 p.m., 2715 Reading Road. $10; free to Civic Garden Center volunteers. civicgardencenter.org. June 17: Foraged Foods Dinner As part of its farm-to-table dinner series, Carriage House Farm features wild and foraged foods from the farm collected by botanist Abby Artemisia and prepared by Nuvo on Greenup. Artemisia will be on hand to talk about local foraging. Dinner begins at 6:30 p.m. at Carriage House Farm, 10251 Miami View Road in North Bend; $125 for dinner, drinks, tax and tip. Tickets available at nuvoatgreenup.com. June 28: Medicinal and Edible Plant Workshop Using plants for food and medicine connects us with our ancestors, say Wes and Diantha Duren of Marvin's Organic Gardens. Their workshop at the Civic Garden Center introduces useful plants to grow in home gardens and shows how to blend herbs to make tinctures and teas. From 10 a.m.-2 p.m. at the Civic Garden Center, 2715 Reading Road. $30; registration required by June 15. civicgardencenter.org.CITY ROOTS is a recurring monthly blog at citybeat.com about local urban agriculture issues.
On Second Thought
'Enquirer'-Kentucky Relationship Strained by Rocky Coverage
Ben L. Kaufman
0 Comments · Wednesday, September 4, 2013
Covering or writing about a community are very different. One requires being embedded; the other is what reporters do when they parachute in and too-often rely on the usual suspects.
Worst Week Ever!
Worst Week Ever!: March 27-April 2
Isaac Thorn
0 Comments · Wednesday, April 3, 2013
Members of the Kentucky state legislature are pondering the merits of "angel investors," while admitting that rich angels are crucial when it comes to competing with Ohio businesses.
Keep Covington Awesome
Northern Kentuckians promote neighborhood spirit with quirky collective
Garin Pirnia
0 Comments · Tuesday, February 12, 2013
A group of Covington denizens known as The Awesome Collective of Covington preceded the "Kentucky Kicks Ass" slogan campaign when they came up with their own strategy to let people know how remarkable their peculiar town of 40,000 people truly is.
by German Lopez
Posted In:
Gun Violence
at 10:09 AM |
Morning News and Stuff
Fiscal cliff averted despite local politicians, defense cuts delayed, wind tax credit renewed
The fiscal cliff was averted, but some Greater Cincinnati politicians didn't do much to help. U.S. Speaker John Boehner voted for the final fiscal cliff deal, but Republican U.S. Reps. Steve Chabot, Jean Schmidt and Mike Turner voted against the deal. Ohio's U.S. Sens. Rob Portman, a Republican, and Sherrod Brown, a Democrat, voted in favor of the deal. U.S. Congress may have averted the fiscal cliff, but the spending cuts were only delayed for two months. For jobs at the Wright-Patterson Air Force Base, that means another congressional showdown in March could decide the fate of thousands of jobs. On the other hand, no one is surprised Congress reacted to a crisis by kicking the can down the road. As part of the fiscal cliff deal, Ohio's wind industry should feel a little safer thanks to the extension of wind energy tax credits. Still, advocates are frustrated funding for wind energy is part of a "stop-and-start policy" that can suddenly continue or end depending on last-minute congressional deals. The Buckeye Firearms Association is training and arming 24 teachers through a pilot program in the spring. A previous CityBeat analysis found no evidence that arming teachers would help stop gun violence; in fact, armed people tend to be in greater danger of violence. Ohio and Kentucky are still in the bottom half of Forbes' ranking for businesses, but they're showing improvement. The Ohio Liberty Coalition, a tea party group, is not happy with Gov. John Kasich. The group is upset Kasich supposedly violated the state's Health Care Freedom Amendment by signing legislation that compels all Ohioans with health care insurance to buy autism coverage. If even conservatives are angry at Kasich, who's happy with him? Cincinnati-based Macy's is closing six stores, but none of them are in the Cincinnati area. Surprise! Research has linked being overweight (but not obese) with lower risk of mortality. During her final days as commander, Sunita Williams of NASA recorded a tour of the International Space Station. A new study found newborn babies know the difference between their native language and a foreign one.
by Andy Brownfield
Posted In:
Is this for real?
at 09:56 AM |
Getting Lucky in Kentucky
Sex dungeon discovered during construction in Louisville
Construction crews working to restore historic apartments in Louisville's Whiskey Row discovered an underground sex dungeon two floors underground. The Associated Press reports that the dungeon had mural reproductions of paintings by the likes of Salvador Dali, Edvar Munch and Fancisco Goya and contained what appears to be a medieval stretching rack complete with winch and rusty chain.The artist who painted the murals tells the AP that he did the work at the request of friends, and the room was meant to attract people who were into sadism and masochism. The artist says the room was only used for one night in the 1990s, but he couldn't remember the year. However, digging deeper into the story, CityBeat learned not to Google "Louisville sex dungeon" on an office computer WHAS-TV spoke with the founders of the club, who said that it was in operation from the mid to late '90s and had close to 1,000 dues-paying members. In stories with pithy titles like "50 Shades of Louisville" (more like "50 Shades of Y'all Need Jesus) the station spoke with one of the dungeon's founders, who said the dungeon included dozens of other bondage and "torture" implements, including a large rope "spider web" with manacles, in addition to the torture rack. Some of the plumbing had "DO NOT HANG" stenciled on it, but the founder said some people were still hung from their ankles. He was quick to disclaim that there was "never, ever any nudity or sex acts." While much of the dungeon has rotted away, Whiskey Row's owners plan on preserving the paintings and torture rack as a link to history.
Next-Generation Lit
The Blue Marble remains a hidden gem for young readers after 33 years of service
Kelly Tucker
0 Comments · Wednesday, June 20, 2012
The stairway to the Goodnight Moon room at The Blue Marble serves as a portal to a simpler, more magical time most of us recall as childhood. The local Fort Thomas children's bookstore this month celebrates 33 years providing literature for children of all ages and interests.
Next »
The Morning After
Clubs and Bars
Music Venues
Just Visiting
Visitor's Guide
Best of Cincinnati
Dining Guide
Bar Guide
About Us
Contact Us
Work Here
Be an Intern
Advertise with Us
Download Our Media Kit
Contact Us
National Advertising


text:
The Cincinnati Bengals defense had to worry about defending Detroit Lions wide receiver Calvin Johnson today, but they were able to get a big strike from their offense early to provide an early cushion.
After Andy Dalton rolled out, wide receiver A.J. Green was able to torch the Detroit Lions secondary to haul in a wide open catch and scamper 82-yards for the score.
Here is a GIF of the touchdown catch, via GIFD Sports:
Dick's Sporting Goods presents "Hell Week":

subset: commoncrawl


text:
We have created a Yahoo group called gorgebirthnetwork. We chose to use a Yahoo group because once you join, the messages will be sent to your email account and you don't need to check this website for new posts. We strongly encourage both new parents and parents with older children to join this group. Our hope is that those with children can answer question and offer advice to new parents.
To view the messages online visit:
To post messages and receive new messages in your email:
Click the "Join this Group" button in upper right hand corner of the gorgebirthnetwork group page. Enter your Yahoo id information if you have one. If you don't have an ID, create a new Yahoo Id. On the "Create Yahoo Id" screen you may enter an alternative email; use this input box to enter your normal email address. Messages posted to this group will now be sent to your email.


text:
[Q] Android youtube app behaviour
1) is there a way to make youtube play in background? If no, WTH?
2) Is there a way for every embedded youtube video (browser, RSS reader) to play automatically in youtube app, or some installed video player? Embedded youtube video performance from those browser/reader apps is catastrophic.


text:
Rocky Men's Ride Waterproof Wellington Work BootItem Number: 24880546
Price: $159.99
Free Shipping Plus Free Returns on Footwear! (See Promotion Details)
Product Information
Customer Reviews
Buying Guide
Immerse yourself in the Rocky® Men's Ride Waterproof Wellington work boot. The 1,000 denier textile upper with full-grain leather trim maximizes durability and delivers supreme waterproof protection. 200 grams of Thinsulate® insulation lock in heat for added warmth, while 3D welt construction boosts integrity for long-lasting wear. The Rocky Ride outsole enhances traction for a sturdy step each time in the Ride work boot.
- 1,000 denier high abrasion textile upper with full-grain leather trim for ultimate durability and waterproof protection
- 200 grams of Thinsulate® insulation lock in heat, increasing warmth
- 8-layer Rocky Ride comfort system with EVA midsole offers intense full-length support
- Rocky Ride footbed maximizes cushioning for remarkable comfort
- 3D welt construction enhances upper integrity for lasting wear
- Rocky Ride outsole boosts grip for optimal traction on all surface types
- Style: 0002867
- Rocky
Country Of Origin: Imported


text:
Media Center
About Us
Message Boards
Facts for Life (by Topic)
Understanding Breast Cancer Guide
Breast Cancer Facts and Statistics
Risk Factors and Risk Reduction
Breast Self-Awareness Messages
Early Detection and Screening
Ductal Carcinoma in Situ (DCIS)
Breast Cancer in Men
Metastatic Breast Cancer
Insurance and Financial Issues
Getting Good Care
Integrative and Complementary Therapies
Survivorship Topics
Breast Cancer Research
Questions to Ask Your Doctor
Komen Perspective
Translated Komen Educational Materials
Komen Toolkits
Voices Of Impact
Find a local Race for the Cure
Become an Advocate
Participate in an Event
Find a Local Affiliate
Join Circle of Promise
Susan G. Komen Passionately Pink®
Careers / Internships / Volunteering
Komen Scholars
Komen Perspectives
Research & Scientific Programs
Advocates in Science
Affiliate Community Health Grants
National Capital Area Grants
Sponsored Programs and Partnerships
Brinker Awards
Research Grants Around the World
Vulnerable Community Grants
Scientific Advisory Board
International Community Health Grants
National Treatment Assistance Funds
Meet Our Partners
Race for the Cure® National Sponsors
Corporate Partners
Become a Partner or Sponsor
Donate Online
Honor Gift
Memorial Gift
Other Ways to Give
Research & Grants
Grants Program
Research Grants
Research Grants Awarded
> Abstract
Research Grants Awarded
A Src Driven Biomarker And Mediator Of Breast Cancer Metastasis
Grant Mechanism:
Postdoctoral Fellowships
Scientific Abstract:
Src kinases are activated in breast cancers, but the mechanisms by which they promote tumorigenesis remains unknown. Considerable experimental evidence suggests that src kinases mediate the metastatic phenotype. However the molecular mechanisms that mediate tumor metastasis and the biomarkers of this phenotype have not yet been defined. Our laboratory has cloned a novel substrate of src kinases named Trask that may be the functionally revealing mediator of breast cancer metastasis. Trask was purified and cloned in our lab as the most highly tyrosine phosphorylated protein in mitotic MDA-468 breast cancer cells. Trask is a transmembrane glycoprotein widely expressed in epithelial tissues and is abundantly expressed in human breast ductal epithelium and epithelial cell lines. However the phosphorylation of Trask is highly restricted in normal cells. Epithelial cells undergo phosphorylation of Trask during mitosis. This phosphorylation temporally correlates with the rounded state of mitotic cells and persists into early G1 and is lost only when G1 cells have re-spread. Consistent with a role in detached cells or in regulation of cell shape, Trask phosphorylation is also markedly induced by forced rounding and detachment of trypsinized interphase cells, and phosphorylation persists until cells have been allowed to re-spread and re-attach. Trask knockdown markedly impairs cell migration and lamellipodial extension, cell proliferation, and interferes with cell rounding and detachment in breast epithelial cells. These experimental data have suggested that Trask plays a role in the regulation of epithelial cell adhesion, cytoskeletal remodeling, or possibly membrane remodeling. In contrast to normal breast ductal epithelium or breast epithelial cell lines, Trask is aberrantly and constitutively phosphorylated in many breast cancers and in many breast cancer cell lines. Trask phosphorylation correlates with detachment and growth in suspension such that cancer cells growing in the rounded non-adherent state have highly phosphorylated Trask. Furthermore, the forced overexpression and constitutive phosphorylation of Trask in adherent breast cancer cells induces growth in suspension. The naturally and fully suspended Du4475 breast cancer cells have constitutively phosphorylated Trask throughout the cell cycle and these cells undergo apoptotic cell death when treated with src inhibitors. We believe that the src-induced phosphorylation of Trask regulates membrane or cytoskeleton changes that are functionally important in epithelial cells while detached from substratum or from their architectural framework. This is important during mitosis, during cell migration and wound healing, during epithelial-mesenchymal transition, and particularly important in metastasis. Breast cancer cells may even require Trask phosphorylation for survival during metastatic migration. In our first aim, we will study the requirement for Trask in breast cancer metastasis using mouse genetic models. We have successfully generated a floxed allele of Trask in mouse ES cells and are currently breeding chimeric mouse. After germline transmission and appropriate backcrossings, we propose to introduce this allele into and eliminate Trask function in MMTV-PyMT mice which develop a highly metastatic form of breast cancer driven by src overactivity. The experimental hypothesis is that the development of tumors or tumor metastases will be significantly reduced or absent if Trask function is lost. In our second aim, we will use in vitro models of human breast cancers to determine whether the src-induced phosphorylation of Trask is a biomarker of src inhibitor sensitivity. The sensitivity of a panel of breast cancer cell lines to src inhibitors will be determined in vitro and in vivo models. For the in vitro models, the sensitivity of breast cancer cells will be studied in adherent and in suspended growth and compared with the already established level of Trask phosphorylation. This is important since Trask may be a marker of sensitivity only while cancer cells are detached. For in vivo studies, we have established a model of breast cancer metastasis using mammary fat pad implantation and resection of breast cancer cells with subsequent detection of lymph node metastases using bioluminescent in vivo imaging. The metastatic propensity of breast cancer cells with highly phosphorylated Trask will be compared to those will unphosphorylated Trask. In addition, the ability of src inhibitor therapy to prevent the development of metastases will be studied. The experimental hypothesis is that the constitutive phosphorylation of Trask is a marker of breast cancer sensitivity to src inhibitors, or that breast cancers are transiently sensitive to src inhibitors during periods of Trask phosphorylation such as when they are detached, migrating, or in circulation. Mortality from breast cancer is directly related to tumor metastasis. Any advance in the field of metastasis has the potential to impact this most lethal consequence of breast cancer. Our work can potentially identify subsets of breast cancer patients in whom metastases can be prevented by src inhibitor therapy. Further down the road, our work can lead to additional targets, such as Trask itself, or other proteins involved in this pathway, which can serve as targets of newer anti-metastatic drugs.
Lay Abstract:
Mortality from breast cancer is invariably related to the development of tumor metastasis. Once developed, the progression of breast cancer metastases is virtually unstoppable and current therapies only minimally delay its natural course. Significant advances in the treatment of metastatic breast cancer have been awaiting a better understanding of the molecular mechanisms that underlay tumor metastasis so that rationally designed therapies could be developed to target this lethal aspect of breast cancer. Considerable evidence suggests that the src family of tyrosine kinases, which are overactive in many breast cancers, are important in driving tumor metastasis. But little is known about the mechanisms by which src kinases promote metastases, and there are currently no biomarkers that can identify in which patients they may be playing an important role. Our lab has been studying how src kinases promote tumor metastases and we believe we have discovered an important new substrate of src kinases that may finally shed light on the molecular mechanisms of breast cancer metastasis and a biomarker that may identify breast cancers that depend on this pathway for dissemination. This new target of src is called Trask. Our preliminary evidence suggests that Trask functions in regulating the shape and movement of cells. This is a function that can be particularly important in tumor metastasis. We have studied many samples of normal breast tissues and breast cancers and breast cancer cell lines and have found that src kinases seem to abnormally phosphorylate Trask only in some breast cancers, but not in normal breast cells. When we eliminate Trask expression in breast epithelial cells, their movements and migration are markedly inhibited. When we overexpress Trask in breast cancer cells, they detach and separate from the other cells, a process that is similar to tumor metastasis. These data have led us to believe that Trask may be a very important target of src, and one which is important in development of tumor metastasis. A breast cancer cell line with highly phosphorylated Trask undergoes apoptotic cell death when treated with src inhibitors. These data have led us to believe that Trask is an important target of src kinases in breast cancer cells and phosphorylated Trask may be the biomarker that identifies breast cancer cells that are being driven to metastasize by src kinases. The central hypothesis is that Trask play an important role in metastasis of breast cancer cells. Thus, it is expected that inhibition or elimination of Trask could result in abolishment or significant reduction in metastases. We will use a mouse model to determine whether Trask is required for breast cancer metastasis. Our lab is developing a mouse model where the Trask gene can be knocked out. We will then knock out the Trask gene in an existing mouse model that develops metastatic breast cancer. If our hypothesis is correct, knocking out the Trask gene will prevent the development of metastases. We are also going to determine whether Trask is a suitable biomarker to be used in clinical trials of src inhibitors. We will determine whether breast cancer cells with highly phosphorylated Trask are especially sensitive to src inhibitors. We will also determine whether Trask phosphorylation identifies specific periods of time, such as during detachment and migration, that breast cancer cells may be sensitized to src inhibitors. This study explores the mechanisms for cancer dissemination. It takes into accounts novel approaches and ideas that have not been pursued before. If hypothesis that Trask is required for metastasis is correct it will be a breakthrough in our understanding of the metastatic process. The aim of this study is to provide genetic and pharmacological evidence that phosphorylation of Trask is instrumental in cancer dissemination. This will not only establish mechanistic evidence, but will provide a desperately needed biomarker for testing src inhibitors in clinical studies. Furthermore, since Trask is expressed on the cell surface, it can serve as the target for newer generations of drugs that seek to suppress the process of metastasis.
Help & FAQs
Site Map
Media Center
Contact Us
Privacy Policy & Legal
Disclosure Statement
Susan G. Komen® For


text:
French Rooster
Looking for authentic French Rooster Gold Coin? The French Rooster gold bullion were produced before the start of World War I between 1901 and 1914 and feature the outline of a Gallic Rooster, the national symbol of France since the middle ages. Today, the French Rooster continues to stand as a proud figure of the fighting spirit of liberty, independence, vigilance, and confidence. For these reasons, the rooster appears on French stamps and is the insignia for the French national sports team.
The French Rooster gold coin is struck with .1867 fine gold making this particular mint very low in price and widely available. These gold coins are ideal for gold bullion collectors who are looking for gold coins that trade near their intrinsic gold value. These gold bullions are also private, non-reportable gold when bought today and most importantly when you later sell them.
Take a look at some of the French Rooster gold coin auctions on eBay today and bid with confidence.
1911 French 20 Franc GOLD Rooster


text:
"Drunkorexia" is a trend popping up on college campuses across the country:
Young women eat less, so they can drink more.
The cycle of restricting eating and then binge drinking could be putting them at risk.
FOX Medical Team's Beth Galvin gives us the skinny on drunkorexia.
KSAZ-TV & KUTP511 W. Adams St.Phoenix, AZ 85003Phone: (602) 257-1234Fax: (602) 262-0177


text:
|Mr. and Mrs. Joe Mueller
|Monday, August 01, 2011 10:04 AM
Joe and the former Diane Odenweller were married on Aug. 19, 1961, at Immaculate Conception Catholic Church, the Rev. Don Mueller officiating. He will also perform their Anniversary Mass.
A family dinner at Dick's Steak House is planned.
They are the parents of Brent (Jean) Mueller of Middle Point and Elise (Nick) Clark and Leah (Nick) Gordon of Delphos. Their grandchildren include Elliot, Anna and Marie Mueller; Alex and Eric Clark; Bailey, Cole and Caitlin Gordon; and grandson Kyle Clark is deceased.
Joe retired from Ford Motor Co., Lima Engine Plant. Diane is a retired registered nurse. She worked at Delphos Memorial Home.
|Last Updated on Monday, August 01, 2011 10:07 AM


text:
Click HERE to view the preliminary program.
(Note: This schedule is a draft and may be modified.)
Guidelines for Presentations
ASL Interpretation
- Any presenter or attendee who requires ASL/English interpretation must contact Cala Zubair (caz6 at georgetown dot edu) by February 18, 2011. Include a list of sessions and/or papers you will attend, including plenary addresses.
- If we do not hear from you by February 18, 2011, we cannot guarantee an interpreter for the session you wish to attend.


text:
This is from a Dolphin fan surfing the AFC blogs. Here is my personal ranking of AFC QB situations for the upcoming seasons. I will take into account the obvious: Great QB's, but will also look "long-term" for 3-4 seasons out to compile my 1-16 rankings for the AFC. Feel free to tell me how dumb I am in the comments section. Only rules are no "predicting" on upcoming draft picks. No one will be able to know who will come out and who will be drafted, or if they will pan out. This is simply the guys on the roster now.
AFC West Denver Broncos: They obviously have the best QB in the division (if not the AFC) right now. Although he is aging and isn't as great as he once was, he will be an elite QB for I think 3-4 more years. Peyton Manning also has an 81.5 total QBR this season, good enough for #1 on that ranking (although I am not always in agreement with whatever the QBR says). They have also drafted his back-up and possible successor in Brock Osweiler out of Arizona State that has potential.
San Diego Chargers: Sad that this is the number 2 QB situation in the incredibly weak AFC West (almost as bad as the AFC East). Philip Rivers is having by far his worst season as a pro (38.0 QBR) and looks to be on the downward spiral. This often happens to "free-lance" QB's that will take chances too often. Now that his great receiving core is either gone (Vincent Jackson) or declining (Antonio Gates) he is being exposed. Still think he is an above average QB, but drop off looks more like an upcoming cliff. Backup situation: Charlie Whitehurst will not be coming in to save the day.
Oakland Raiders: This is number 3 in the division (thank you Kansas City for being that bad)!? Carson Palmer is actually a pretty serviceable QB despite his 44.6 QBR. Oakland is just such a mess everywhere else it is hard to know if it is Palmer falling off or that he was put in the land of disorganization. I think they may have the best backup of the division in Matt Leinart if he can develop some more.
Kansas City Chiefs: Number 4 in this division is not a great place to be. Still not sure if Brady Quinn or Matt Cassel would go as starter or backup. Either way this team is near the bottom and like Miami they are bad on the wrong year to get a stud QB so they will have to find some more stopgaps until they can stink really bad on a good QB year.
AFC North: Pittsburg Steelers: Whenever you have a guy in Ben Roethlisberger that has 2 super bowl wins in his pocket and is relatively young, you should be set. Only thing they get counted off for is that as "young" as Big Ben is, I think he has the Kevin Garnett syndrome (body is aging rapidly from all the wear and tear). That is about all I can give them negative marks on in the starter category. Now the backups are terrible and old (Charlie Batch and Byron Leftwich).
Cincinnati Bengals: This may shock some people, but I am a big Andy Dalton fan and he is only in his second year. They also get high marks for having great tools (AJ Green ) around him. Dalton also seems to be on the way up despite a small sophomore slump and has turned around an entire franchise that was inept before getting him with a 2nd round pick. Backup situation: Brad Gradkowski is not a long-term guy, but they shouldn't need a long term fill-in with such a young QB.
Baltimore Ravens: Joe Flacco has fallen off more than most people may realize (44.6 QBR) this season, which is also a contract year. My guess is Baltimore locks him up for the long-term. He is definitely a solid QB that can do well (AFC championship last year) with great players around him, but he is looking more and more like a Trent Dilfer than an above average QB. Backup situation: Tyrod Taylor scares nobody and would be a huge drop off from Flacco. ##Would not be surprised to see them use mid-round pick on a developmental QB this season.
Cleveland Browns: In a QB rich draft class, Cleveland got the 5th best QB out of 6 playing now (maybe 7th if you count Kirk Cousins). Brandon Weeden is an upgrade from what they have had, but will never be a superstar and his age is a huge knock against him. I'd say below average starter for the next few years, until they have to draft another QB. Backup situation: Colt McCoy. I think McCoy may be one of better backups in the league and could be not much, if any, of a dropoff from Weeden.
AFC South: Indianapolis Colts: This kills me to put them this high on the list, but talk about some (Andrew) Luck in being terrible at the right time (Once for Manning, then Luck). I think he is the best QB of the class, although if RG3 can healthy and Tanny develop's he will have some challengers. He doesn't have great numbers, but has completely turned around a franchise and to me his come-from-behind wins are great also. Backup situation: Drew Stanton. Doesn't really even matter does it?
Houston Texas: Matt Schaub is a good QB in this league. Not elite despite as his 66.0 QBR shows, but good enough with a running game and defense to get you deep into the playoffs. Has great weapons around him and I feel he is a step above Flacco as a QB. Backup situation: May be one best in league as TJ Yates proved he can win late in the season and in the playoffs.
Tennessee Titans: Jake Locker may be a very solid QB. The problem is he keeps getting hurt, so we may never know. He is very raw, but I see huge potential in him. Still puts them at 3rd in the division. His 52.8 QBR puts him at 19th in the league with the potential to go up. Bad thing for the Titans, potential doesn't equal wins, just a hope. Backup situation: Pretty solid with Matt Hasselbeck, although this may go down in the near future as Hasselbeck is getting up there in age.
Jacksonville Jaguars: Not sure who the starter is, but let's say it is Blaine Gabbert. Ranked 30th with a 30.9 QBR, and that may be being nice. The sad thing in Jacksonville is they have the tools around him to be successful. One of the teams in the league that could be almost playoff caliber with just a solid QB. It is a sad day when I think Tim Tebow would be a huge upgrade for them (and I am a Tebow lover, but know how limited he is). Backup situation: Actually not too bad. Chad Henne is not a great starter in the NFL, but is a good backup with starting experience that typically won't lose you games, although he also rarely will win them either.
AFC East: New England Patriots: Not much of challenge here as the Patriots have been tearing up the NFL for the last decade behind Tom Brady. This year he has a QBR of 78.8 and is doing very well with average wideouts, but spectacular tight ends. He is getting up there in age, but like Peyton Manning, guys that aren't known for running the ball tend to last longer in the league. I could see him there at an elite level 4-5 years (that kills me to say as a Dolphin fan). Backup situation: Ryan Mallett has all the tools to be great and with a great offense and QB to watch he should be solid.
Miami Dolphins: Ryan Tannehill was considered a huge project for Miami coming into the season. He has proved to already be ready to keep his team in most games and rarely makes mistakes. With a very limited receiving corps he has kept Miami competitive. Probably right now the 3rd – 4th best of the rookie class, but may have a much higher ceiling than Wilson of Seattle. If not for a few missed FG's Miami would be 8-6 and you'd hear a lot more about him. Backup situation: Very solid. Matt Moore, if he stays in Miami as a backup after this season, is very capable of coming into games and winning. He has already proved that this season in a win over the Jets.
Buffalo Bills: 3rd in this division shows how weak the East is in QB's. Ryan Fitzpatrick is not a terrible quarterback, but he is not going to do much to strike fear in a defense and often makes very poor choices (which he cannot get away with because he is also limited physically and in arm strength). I think Buffalo's team with an above average QB would be a playoff contender, but with Fitzpatrick running the show they look to be fighting to be .500 each year. This season he has a 45.1 QBR. Backup situation: Tyler Thigpen is not going to do much for you if he were to come in off the bench. Word is Buffalo may be targeting a QB in the near future.
New York Jets: Mark Sanchez has failed. He has a 29.1 QBR and has had 4 seasons with the Jets. Once teams realized he struggled with any type of pressure he had no chance. Not only does he make very few great throws/plays, but he makes game killing decisions. INT's seem to just jump off his hand, especially in the red zone. Backup situation: Other than the overkill in the Media, I think Tebow should actually be starting for them. He is not a great starter at QB for the long term, but he is better than Sanchez. My gut tells me team would have been 2-3 wins better this year if Tebow plays from week 1. As a Dolphin fan I am thrilled to see Ryan stick by Sanchez. Overall rankings:
1) New England Patriots: Tom Brady is the class of the NFL right now and he has the better backup than Denver. Trending: Even 2) Denver Broncos: Payton Manning has answered any questions about his health. Have young backup also. Trending: Up 3) Pittsburg Steelers: Health concerns are only question here with Big Ben. Backup situation not very good either. Trending: Even 4) Indianapolis Colts: Andrew Luck looks to have potential to be elite. Not there yet (has to cut down turnovers), but very close. Backup situation looks good, but it doesn't look to matter for about 15 years. Trending: Up 5) Cincinnati Bengals: Andy Dalton may be right below elite level. But he is very solid and rarely makes mistakes. He can also win games for you. Backup situation again doesn't matter much. Trending: Up 6) Houston Texans: Matt Schaub is another example of solid QB play. Not going to win games by himself, but rarely makes big mistakes and usually makes plays that are routine type NFL QB plays. Backup situation may be best in NFL. Trending: Even 7) Baltimore Ravens: Joe Flacco would have been much higher coming off last season, but in a year he needed to carry team he has been exposed somewhat. Still the answer for the Ravens, but will never be elite. Does get bonus points for winning playoff games last season. Backup situation is not very good either. Trending: Down 8) San Diego Chargers: Philip Rivers has really struggled last few years. Tempted to put him lower, but still see him as a guy that will win games for his team by himself. The flip side: He will lose games by himself. Backup situation not great either. Trending: Down 9) Miami Dolphins: Ryan Tannehill seems to be the answer for the Dolphins. Could make big jump up after this season as he gains experience and hopefully play-makers this offseason. Backup situation is one of best in NFL. Trending: Up 10) Tennessee Titans: Jake Locker has been undone with injuries, but I see big potential in him. Problem now is inconsistency. Backup situation is very solid. Trending: Even 11) Buffalo Bills: Ryan Fitzpatrick is not who I'd want as the face of my franchise, but he is not at the bottom level as some of the next QB's are. Backup situation is not great. Trending: Down 12) Oakland Raiders: How sad is it when Carson Palmer is above 4 other teams? Backup situation not great either. Trending: Down 13) Cleveland Browns: Brandon Weeden may be the answer. Not a great statement when I guy is 30 years old and no one is sure about him. Colt McCoy is a solid backup. Trending: Even 14) Kansas City: This ranking is only because they are not tied down with either Brady Quinn or Matt Cassel. They know both are not the answer and are ready to move on. Trending: Down 15) New York Jets: Thought about putting them at the bottom, but Mark Sanchez is better than Blaine Gabbert or Chad Henne. The problem is they are tied to him for at least another year. TEBOW! TEBOW! TEBOW! Will replace the J-E-T-S chants next year if he is still there. Trending: Way Down 16) Jacksonville Jaguars: Neither guy they have now is the answer, although Henne is an above average backup in the NFL. Trending: Down


text:
UFC 152 has gone through some significant changes as a direct result of the cancellation of UFC 151, including a new main event of Jon Jones and Vitor Belfort to assure us two title fights on September 22nd. Of course, that meant one fight had to go from the main card to prelims on FX, and unfortunately Evan Dunham yet again is on the prelims. His fight with T.J. Grant isn't even the leading fight on FX, that belongs to Igor Pokrajac vs. Vinny Magalhaes. In an interview with MMA Weekly, Dunham expressed his thoughts about no longer being on the PPV.
"Definitely when I first heard about it, I was bummed out about not being on the main card," Dunham told MMAWeekly Radio.
"I know that I always put on good performances. I think I put on fights that people like to see but it was the main card. I got bumped, I was a little bummed, but there was nothing I could do about it. I just realized it is what it is and decided to move forward."
For someone who is 6-2 in the UFC with 2 FOTN performances and a SOTN win, Dunham has been on a PPV main card exactly once. His excellent fight with Sean Sherk was the best fight at UFC 119 (not that many other fights could challenge it) but Dunham fell victim to ridiculous judging. Unfortunately, because of that awful split decision loss, followed up with Melvin Guillard's KO of him in January 2011, he fell off the contender radar. He's since beaten Shamar Bailey and Nik Lentz, both on prelims of free shows, and is trying to put his name in the crowded hat of LW contenders.
I really don't think Matt Hamill vs. Roger Hollett should be on the main card ahead of Dunham/Grant, especially given that Hamill/Hollett is essentially an irrelevant fight, but the positive is that Dunham still gets TV time on FX. There would certainly be more reason to be upset in the "dark fights" age of UFC prelims before September 2009. Hopefully an impressive win for Dunham would mean A.) He starts getting top 15 guys again and B.) He finally gets back on the main card.
SBN coverage of UFC 152: Jones vs. Belfort


text:
Oh blah blah blah. Here comes another national football talk show. Great. Let's hear it boys. Tell us about Mike Vick, and Tom Brady, and the Jets and whatever the hell else is happening with the Cowboys. Just keep talking about all that teenager chat.
And you know what?
In Jacksonville, we'll keep ignoring you. Because, here, football happens on the field. It doesn't happen in your make-up rooms. In doesn't happen in your producer's office. It doesn't happen on your tour bus.
This is a field game. Down where the nostrils and armpits roam. And tonight, the Jaguars had the nastiest. Try and work that through your ESPN computer. Or squeeze that through your weird Merril Hodge neck collar. Anyone? Hey, Chris Berman, catch a hypertensive breath and name one Jaguar defender for us. Would ya?
Or don't. It doesn't really matter what you do. Real football fans just love their team, and the game. Not the hype. And for a hype-less team, tonight was all game. And it was a game that belonged to the Jaguars.
Go Jags! Onward. The Teal and Black ARE Coming Back!


text:
Find listings of Oxford 27565 Foreclosures for Sale. Our Oxford Foreclosures for Sale help you locate the best Oxford 27565 Bank Foreclosure Listings. You can find all related information about Oxford repo homes, foreclosure homes and bank repo homes.
A quality foreclosure listing service will not only help you find the most affordable Oxford 27565 Foreclosed Homes for Sale in the state of North Carolina, it will also provide you with timely and accurate information.
ForeclosureRepos.com, for example, offers members an extensive database of foreclosed homes that include North Carolina bank foreclosures, federal government foreclosures, and cheap homes. Our site will also alert you to all upcoming foreclosure auctions as well as distressed properties and those that currently have tax liens.
ForeclosureRepos.com boasts the most comprehensive and up-to-date listings of foreclosed homes and government foreclosures in Oxford 27565 today.
Our bank foreclosures database is updated daily, providing the latest foreclosure records from America's most trusted banks, like: Bank of America home foreclosures in 27565 Zipcode, Wells Fargo foreclosures for sale in 27565 Zipcode, Fannie Mae and Freddie Mac 27565 Zipcode listings, JP Morgan Chase homes for sale in 27565 Zipcode, Citibank 27565 Zipcode homes for sale, Wachovia foreclosures in 27565 Zipcode, Suntrust 27565 Zipcode foreclosures and HSBC reo homes in 27565 Zipcode.
© 2014 ForeclosureRepos.com All rights reserved. Terms and Conditions and Privacy Policy.


text:
The northbound lanes of U.S. Highway 59 have been re-opened Thursday morning, after being closed for hours when an oversized tractor trailer hit a railroad bridge.
Union Pacific Railroad crews and the Texas Department of Transportation worked through the night to repair damage to the railroad bridge and it was re-opened just after 5 a.m., Thursday.Wednesday evening, Randy Black was driving the 18-wheeler and missed the signs for him to go on the right route with his oversized load and hit the railroad bridge, according to DPS.
Pieces of Black's load flew off after making contact with the bridge.
Lance Hetrick of San Augustine was behind Black and ran over the debris busting his oil pan and disabling his car. It was towed off the scene.
No injuries were reported.
Slocum says Black was cited for disregarding permit limitations.
TXDOT Public Information Officer, Kathi White reminds motorists that this area is an active work zone, so use caution when driving through the area.
Copyright 2013 KTRE. All rights reserved.
358 TV Road,
Pollok TX 75969
FCC Public File
EEO Report
Closed Captioning


text:
Do you all think this PC is worth $400: http://rockford.crai...3678607067.html
A guy offered to trade me that PC for my 2012 MTB that I have about $900 into ( with the 3k miles on it I only put a value of $400 on the bike ).
Do you all think I could resell that PC quickly for $400 or is the value of his PC too close to $400 to be worth the risk of having to try to unload that over my bike?
It looks like his case is an Antec 900 and the HDD is a Seagate and is not an SSD like his ad says, I'm assuming it was a typo in his ad. Also the ram appears to be OCZ Gold DDR3 judging by the pic but I could be wrong but being only a 2x2gb kit I don't think the brand/model matters at all for DDR3.
He did say it has an 802.11n wifi adapter but again, don't know if that matters at all for value. And the optical is just a dvd burner.
Edited by WARDOZERX, 14 March 2013 - 12:02 AM.


text:
Call Us:
Toll Free: 1-866-MY-ARRAY
Domestic: email@example.com
International: firstname.lastname@example.com
Application delivery controllers by Array exceed enterprise performance and technical requirements without exceeding your budget.
Speed up data and applications between any cloud, data center, office or user. Accelerate your business with dedicated and virtual WAN optimization controllers by Array.
Instantly mobilize enterprise applications, expand remote access usage and enable BYOD without drowning in cost, complexity attacks or data leakage.
Scale to new heights offering load balancing, WAN optimization and secure access services that profitably align your infrastructure costs with customer demand.
Proven in over 5000 worldwide customer deployments, Array Networks is a global leader in application delivery networking.
Powered by SpeedCore™, Array application delivery, cloud and mobility solutions are recognized by leading enterprise, service provider and public sector organizations for unmatched performance, reliability andtotal-value-of-ownership.
Learn how Array can help with your application delivery, cloud and mobility needs.
Watch Video
October 17 - 20, 2014
Orlando World Center Marriott
Orlando, FL
Request a Meeting
30-day free trial of Array load balancing, secure access and WAN optimization.
Download Now
"For our clients that need to scale, Array load balancers provide significant cost savings in hardware, maintenance, set up, rack space and power."
Orlando, FL, October 17-19, 2014
eCW National Conference
Phoenix, AZ, November 6, 2014
Data Connectors Conference
Toll Free: 1-866-MY-ARRAY
Domestic: email@example.com International: firstname.lastname@example.com
©2014 Array Networks, Inc. All rights reserved.
Market Automation


text:
Archive for February 2011
The Middle East's Next Generation
Last year, I had the priviledge and honor of being a Global Teen Leader (GTL) by the We Are Family Foundation (WAFF). WAFF, founded by musician and producer Nile Rodgers, created its Three Dot Dash GTL program in honor of the life of peacemaker Mattie JT Stepanek. Mattie, who died right before his 14th birthday, was a child prodigy and peacemaker, writing a book with Jimmy Carter. According to Mattie, each one of us has a heartsong, or a special gift within us that is meant to be shared with the rest of the world. Each of the GTLs, now at 90 worldwide, shared Mattie's committment to making the world more peaceful.
Yesterday, I received an email on the Three Dot Dash Global Teen Leader listserv that went something like this:
Our brother Mahmoud Jabari – 2008 GTL – from Palestine was arrested by the Israeli troops two days ago during the Hebron Protests!
The GTLs have launched a global campaign, including a petition to free him. He was chosen by the United Nations to deliver this message to the Security Council in a few months, and we have thus reached out to Ambassador Susan Rice to notify her and ask for her guidance to ensure minimal pain.
Mahmoud, a peacemaker, journalist, and founder of Lens for Change, represents what the Middle East needs. As the generation of those who were not alive, and whose parents were not alive, during the creation of Israel about 60 years ago begins to enter their early 20s, people like Mahmoud will be critical to bringing peace to the region. As the stories of the aftermath and the atrocities become more and more distant and as Israel becomes remembered as something that has always been there, the window of peace will crack open a little bit more. When it does, I hope the globalized Generation Y, led by people like Mahmoud, feel the breeze of peace rather than shut the window completely.
Update (3/3/11): Mahmoud was cleared of all charges and released. Thrilled and deeply inspired by the tremendous effort of the PBSNews Hour, Seeds of Peace, The Daniel Pearl Foundation, iEarn, Mattie J.T. Stepanek Foundation, Relief International, the We Are Family Foundation, and the GTLs!
Mobile Printing
The digital world and the physical world have merged in tremendous ways over the past three years. Computing power has become nearly ubiquitious, mobile phone usage is often more pervasive than access to clean sanitation in the developing world, and technologies like Sixth Sense, GPS, and Red Laser are moving us that much closer to eliminating the line between what's digital and what's physical. They are also making us that much more dependent too, with many formerly tangible services (phone books, travel agents, journals, and even financial transactions) being moved completely online.
But one connection that still hasn't mobilized or changed in a meaningful way is printing from computers or mobile phones. Dominated by large, public, dominant companies of the early 2000s (HP, Compaq, etc.), printing hasn't changed much. Color printing, laser printing, and wireless printing have all happened within the last 5 years, but the actual hardware has remained the same: large, stagnant, and immobile.
Beign able to take laptops and iPhones on trips and into meetings are revolutionary, but if we need to print something and aren't in our home or office, they are pretty useless. Often, the only time college students, who study all over campuses, need to come back to their room's desk is to plug their USB cable into their laptops to print.
We need laptops or iPhones with the ability to print small amounts of paper directly out of the laptop or phone itself. Although this may slightly bulk up the design of laptops and be impossible in products like the Macbook Air, I bet cartridges and other components could be designed cleverly enough to make the change hardly noticable.
Mobile printing could be a small addition that could disrupt the printing industry completely. In fact, it could almost eradicate it like cell phones have done to landlines.
Voyurl: Blippy on Steroids
I've been closely in touch with Adam Leibsohn over the past year as he has developed Voyurl. Adam is the passionate founder and former designer, which explains the eye-popping look of the current interface. He sent me an email this morning updating me on the progress and I was impresssed yet not surprised.
Blippy allows you to broadcast your credit card transactions and purchases to the public and to your friends. Voyurl goes a step further: allowing you to broadcast in real time, to your friends and to the public, your site history. In other words, when you're visiting a website, it isn't just the website host or your ISP who know. But everyone.
You can also choose to go anonymous or not broadcast certain websites. Certain destinations, like online bank accounts, are also off limits.
There is clearly a business in the information. It could allow advertisers to target precisely down to the very person, combining their Facebook profile data (if they use FB Connect) with every site they visit. It could gather data on the very patterns of behavior of website usage amongst different demographics. And, it could serve as a direct referrer for online purchases and unique deals, similar to Facebook's newsfeed.
But who would ever use it? Well, it seems like a lot of curious people. They're about to hit 1,000,000 links shared in three weeks in their private alpha. With some more controls on what one can share and a prioritized list on what people are seeing, Voyurl could become a wacky, but relevant and widely-used product.
So go ahead. Take a peek inside. As Voyurl's tag line goes, it's okay to look.
But don't forget, people are looking at you too.
Timing and Valuation
I met with a friend, the CEO of a very cool Internet startup in San Francisco who had just closed his Series B. In the current "bubble" of Internet company valuations, I was surprised at the valuation of his growing, hot, revenue generating company. As someone who generally thinks prices are too high in today's Internet deals, his wasn't as high as I thought it should and could have been.
As a comparison, a new competitor in the same space just closed their Series A. This competitor is doing less than 1/10 the revenue of this CEO's company, doesn't have as developed of a product, yet raised their Series A at the exact same price as the Series B of the first company.
So what happened? Was the competitor's price too high? Almost definitely. Why? Apparently, they had one of the best pitches most investors have ever seen and had created an amazing hype around the business, engaging two top VCs in a bidding war. But was the CEO's company undervalued? Almost definitely too.
It turns out that this CEO had gone out to raise the follow on financing too late. He was presenting to firms only six weeks before his company was going to run out of cash. In fact, the price would have been even lower if another VC had not come in and bid up the price to the current level. Generally, with the exception of the stories of VCs not letting CEOs leave pitches without taking a check, it takes VCs at a minimum at least 3 weeks from beginning to money in the bank. And that's assuming the company is perfect, the valuation is spot on, and nothing goes wrong.
The lesson: it may seem obvious, but seems to be forgotten when CEOs are heads down trying to run their companies. CEOs generally want to start fundraising as late as possible so they can show as much progress as possible, which should value the company higher. But sometimes they start too late. CEOs of young companies should be sure to start fundraising at least 3 months before money is going to expire, with a target of closing at least 1.5 months before, or else risk getting hit on valuation to save the company.
Lessons from Discussion w/ Stanford President Hennessy
As part of a group, I was invited to a lunch discussion with Stanford President John Hennessy earlier today. He is on the boards of Google, Cisco, Atheros, and the Daniel Pearl Foundation; was the founder of MIPS; and just sat down with President Obama last week.
Key takeaways/viewpoints of his that I found interesting:
- One thing that makes America great is that failure is not fatal. However, it can also be its weakness, as that is fundamentally what caused the financial crisis.
- Politics have moved away from the Jeffersonian ideal of it being a step away from your "normal"career. It has become a full time career for people and that is troubling.
- Authoritarian leadership doesn't work in any great company.
- One of the most important character traits of his that made him President was that he was always honest, but gentle, especially when delivering bad news.
- Reputation is critical. It is like a flame: easy to build up, but once extinguished, it is tough to light again.
The Return of the Professional Athlete Role Model
It seemed like the past five years, all we heard off the field was sports athletes in jail, getting arrested for alleged rape, dog fighting, taking steriods or drugs, and sending lewd photos.
Michael Vick. Ben Roethlisberger. Brett Favre. Plaxico Burress. Maurice Clarrett. Mark McGuire. Kobe Bryant. And the list goes on and on and on. It seemed life half of the NFL or NBA was on probation, in a lawsuit, or at some point had a run-in with the police. And it felt like half of the MLB was on steroids after the Mitchell Report came out.
Professional athletes, once role models to almost every kid who dreamed of playing under the bright lights of Madison Square Garden or in the snow at Soldier Field, suddenly became the definition of crime, thuggery, and poor values.
But as I've started to recently hear more stories like the Eagles flying from LA to NYC to get the back of a bullied kid or Mark Sanchez befriending an 11 year old with rhabdomyosarcoma, I'm starting to believe that the trend may be reversing. The NBA Cares initiative, the MLB teaming up with the Susan G. Komen foundation to swing pink bats for breast cancer, and the NFL's Tribute to the Troops are examples of the organizations' focus on restoring league-wide images of peace, goodwill, compassion, and benevolence.
Small actions, but they speak volumes for the return of the professional athlete role model. And while there is a ways to go, I'm optimistic and very happy to see these steps.
NBG & IRE – History Repeating Itself?
I have been following the European debt crisis closely and decided last May to put money in Greece's largest bank and top 10 employer, National Bank of Greece (NBG). I cashed out for a small profit in early August, and then bought the stock again a little too early in September as it slid.
I also bought Allied Irish Banks (AIB), one of the Big Four commercial banks in Ireland, in October. AIB was against my thesis of investing in only too-big-to-fail debt-ridden European banks, so I preserved what was a (lucky) profit after a month of it being in the red and sold it in December. Indeed, two weeks later, the government nationalized the bank and the stock plummetted.
I should have bought Bank of Ireland (IRE) instead. In fact, if I didn't have my current position in NBG, that is the first stock I would buy.
I could be completely wrong, but IRE and NBG feel like history repeating itself and strong buys. They are:
- The largest banks in their countries and huge employers
- Have a diverse set of assets in different markets (especially in the case of NBG)
- Trading below book value and close to their ten year lows
- Have been bailed out by the EU
- Will probably require additional capital or a government buyback of debt
Sounds a lot like Citigroup right after the financial crisis, which went from $1.03/share in March 2009 to over $5/share in August 2009. And although the situation in Europe today is considerably different than the US situation in 2008 and 2009, I'm betting on one thing.
Too big to fail.
No More Cars
A hundred years ago, New York City had a manure problem. The average horse produced between fifteen and thirty-five pounds of manure and it piled the streets. It was a huge health hazard due to the disease, it was a large nuisance, and it was growing. People began thinking of better manure removal and cleanup solutions, even trying to burn it.
Meanwhile, Henry Ford, in southeastern Michigan, produced the Model T. He revolutionized transportation and eliminated the manure problem.
I see the the future of transportation as similar. Part of the current hype is around cleaner, more efficient transportation systems: perhaps we need cleaner vehicles, electric vehicles, and hybrid vehicles. Perhaps the right fuel isn't our current natural gas, but some sort of cellulosic based ethanol. Perhaps we need narrower cars to fit more on the road, similar to Commuter Cars.
Or, perhaps, our transportation system, once again, has become outdated. As our populations continue to increase, we will continue to see more traffic jams and gridlocks, perhaps even more to the extent of last summer's 60 mile long gridlock in China.
Dirt roads became paved roads after the Model T. In 50 years, perhaps the paved roads could be upgraded once again: to include powerful magnets. Perhaps the future of transportation is not in cars, but in some sort of magnetic levitation system that can cleanly, safely, and quickly transport a large number of people.
It's something to think about, especially as large cities known for their traffic problems—Mumbai, Jakarta, Beijing, and Sao Paulo—continue to experience population growth with limited infrastructure change.
Sparing Skype
I've finally begun! The main purpose of this blog is to spare my loved ones incessant Skype messages, text messages, phone calls, or emails about various articles or topics I find interesting and instead to post them here. If you derive some value out of this, then even better.
Investing. Venture Capital. Inspirations. Social Change. Development. Sports. Gambling. Music. Hotels. Chipotle. Everything.
Hope you enjoy!


text:
NCBS announces its 4th annual science journalism workshop, which will be held on campus from July 23 to August 7, 2014.
Harold Varmus, Nobel Laureate and Director of the US National Cancer Institute (NCI), visited the National Centre for Biological Sciences (NCBS) on 21st January 2014. Varmus interacted with scientists working at NCBS and other Indian institutes to assess the status of cancer research in the country and draw out priorities in research. Based on these interactions, Varmus hopes to determine ways in which India and the United States can work towards boosting cancer research.
"The meeting with Varmus was to mainly give him a perspective of what is going on: in cancer research as well as others that can connect to cancer research in some way," says Satyajit Mayor, Director of NCBS and InStem. "Varmus was chiefly interested in exploring how to link up cancer research in India with research going on outside the country."
Three Grade 12 students from the Central School for Tibetans at Mundgod in Karnataka are currently interning at the National Centre for Biological Sciences (NCBS). Following an agreement with their school and the NCBS, Tenzin Tsetan, Tenzin Phentok and Tenzin Zomkey began their internship on 6th May with Professors Uma Ramakrishnan, Vatsala Thirumalai and Axel Brockmann.
Aristotle's maxim holds especially true when it comes to scientific research - where the diversity of disciplines adds so much more to forge the gigantic whole. And collaborations are key to the multi-disciplinary approaches that have fostered many contemporary science successes today. Now, after nearly ten years of ongoing collaborations between NCBS and the RIKEN Kobe Institute in Japan, the Bangalore Bio-Cluster comprising NCBS, inStem and C-CAMP has signed a memorandum of understanding (MoU) with RIKEN Japan. The MoU will strengthen ongoing collaborations, now extending to all RIKEN institutes across Japan, promote graduate and post-doctoral exchange programs between the organizations involved and potentially also set up a new research center in the premises of the Bangalore Bio-Cluster.
Music is a curious thing. At face value, it seems to be an abstract concept, one that does not seem to be essential to human survival. Yet music is arguably as old or older than language itself, and ubiquitous in human culture. Indeed, it is an aspect of culture that seems to be ingrained in our species. Music has a profound effect on the human mind and emotion. However, for something that has such a powerful effect on us, we understand so little about it.
With a melange of art, science and hacking, HackteriaLab 2013 is beginning today at NCBS. No, not the kind of computer hacking that comes first to our minds when we hear that word.
Alternative healing systems have always been part of Indian tradition: from local medicine men to the vaidyas or physicians of the more classical unani and ayurveda. The popularity of these remedies took a beating with the advent of allopathic medicine. But traditional medical systems are coming to the fore once again and enjoying renewed interest.
With the Annual Talks finishing two days back, I sent out an email to our student, junior research felllow and postdoc mailing lists asking for comments. I have compiled the responses to date, while things are still fresh in our memory. One question focused on the new conference-style format: instead of every PI giving a talk, about half the faculty did, and there were also outside speakers. Please use the comment section below this article to add any further thoughts! All photos are by me, and are from the final day's poster session.
What were you favourite talks?
* I found Benny Shilo's talk good mainly because I could relate it to my research work. I also found Nicolas' talk and work very interesting though I don't do anything related.
* Favourite talks: Nicolas Gompel (really interesting work), Jayant (introduced comments which made his talk lively), Krushnamegh (hearing him for the first time) and Pedro (very different work and model system, also highly organized presentation) in that order.
One of the most prestigious awards in science, the 2012 Albert Lasker Award for Basic Medical Research, was announced yesterday, and all three recipients - Jim Spudich, Ron Vale and Michael Sheetz - have strong links to NCBS, and India generally.
Jim Spudich, from Stanford, has had a long association with NCBS and is currently adjunct faculty here. Like Vale and Sheetz, Spudich's work has focused on 'molecular motors' - intracellular molecules that can harvest chemical energy to generate force. Spudich's group has been at the forefront of discovering how the motors that power muscle and other intracellular movements -myosins- do their jobs. In particular, his laboratory has developed in vitro assays that measure the speed and force produced by myosins -and are exemplars of experimental elegance. The assays allow researchers to determine the movements and forces produced by single myosin molecules. At inStem, Spudich is now leading a team investigating the role of myosin and other proteins in inherited cardiomyopathies, visiting inStem/NCBS three to four times per year.
Daniel Louvard, Director of the Curie Institute in Paris, visited NCBS last month to sign a Memorandum of Understanding (MoU) between the Curie and NCBS. We managed to 'steal' him away from the commotion and badgered him with questions about the MoU, the new opportunities it might give to the students of NCBS and his views on current cancer research.
Supriya: How did this collaboration come about?
Daniel: Ludger Johannes had a number of interactions with several groups here, from your institute, NCBS, and they came to the idea we should formalize our interaction. So, a year ago, a year and half ago, Ludger came to my office and said it would be good if we can formalize that by a document that really reinforces our interaction, and I say, that's a good idea. So this is how the collaboration came about. This is a document that really confirms formally an existing collaboration between groups and so there's a clear understanding of what we are doing together.
NCBS microscopists are invited to submit several of your images and/or digital video clips to the 2012 Olympus BioScapes Digital Imaging Competition. As indicated by its title, the compettion will honour extraordinary microscope images of life science subjects. Up to five images, videos or image sequences can be entered per person, and you do not have to be a user of Olympus equipment to join in the fun. Entries for the contest can be uploaded through a web browser directly to the Olympus servers at the following URL:
http://www.olympusbioscapes.com/enter.asp You have exactly one month to hunt through your archives, or capture some dazzling new images. The deadline for new entries is Tuesday, October 2, 2012. The winning photos of the competition are tentatively scheduled to be published in Scientific American and the photographers will receive substantial material rewards. First prize will be Olympus microscope or camera equipment valued at $5,000. Nine additional winners will also receive valuable prizes from Olympus. Winners will be notified in late October, and publicly announced in December, 2012.
The Master's course in Wildlife Biology and Conservation is an unusual place. In a literal squeeze of blood, sweat, and tears, students undertake a large part of their learning while scrambling over hill tops, slashing through scrub forests, wading through streams, and walking many sweaty miles looking for animals and plants. Leading from the front, or sometimes whipping tired rears into action, is Ajith Kumar, the director of this wildlife course offered by National Centre for Biological Sciences and Wildlife Conservation Society-India Programme. For over 25 years, Ajith has been mentoring students in the field of wildlife biology and conservation.
The Science Journalism Course is back at NCBS, now accepting applications for its 2012 batch. But what was it like to be part of the first course held in 2011? What are its alumni doing now? That's something this year's prospective participants will be curious to know.
NCBS announces its 2nd annual science journalism workshop, which will be held on campus from July 11 to July 27, 2012.
With basic scientific help from NCBS's Navneet Rai and Mukund Thattai, a team of students guided by Yashas Shetty from the Srishti School of Art, Design and Technology at Bangalore have done it yet again: an award at the famed International Genetically Engineered Machines (iGEM) competition at the Massachusetts Institute of Technology (MIT) at Cambridge, Massachusetts in the United States of America.
Ashtavaidya Ayurveda is a unique medical tradition prevalent in Kerala. It is thought to be an amalgamation of text-based Ayurvedic practices and regional folk medical practices of the south Indian state. Scholars Annamma Spudich and Indudharan Menon had interviewed the last remaining practitioners of the tradition as part of the "Living History of Indian Scientific Traditions" archive initiated by NCBS.
Now, the Science and Society programme at NCBS presents "A Scientific Approach to Traditional Medicine" - a dramatic exploration of Ayurveda and Ashtavaidya medicine. The play will be presented by the students of NCBS and is directed by Jeff Teare, co-director, TheatreScience (UK).
"Just the workshop on Wikipedia editing," I told myself at the start of the conference. It would come in handy to start and edit NCBS wikipages, part of my work at the NCBS News team. "And maybe just the first plenary talk too". At the end of the three-day Student Conference on Conservation Science (SCCS), I realised I had attended almost every session: plenaries, student talks, workshops, poster rounds and discussions. What had made it so engaging?
* Deccan Herald covers NCBS PI Krushnamegh Kunte's work on Bangalore's butterfly populations * "A man of science": Obituary of K.S. Krishnan by K. VijayRaghavan in the Indian Express * NCBS student among discoverers of a new species of gecko in Western Ghats* K. VijayRaghavan elected to the US National Academy of Sciences: The Hindu* Diverse gene pool critical for tiger survival, says NCBS and Stanford-led study* "Will tigers march ahead?" NCBS's Uma Ramakrishnan's research covered by MongaBay* ScienceCareers talks to NCBS's Axel Brockmann and the Mercers about careers and life in India * NCBS finds no human DNA in faeces of captured tiger* The Hindu covers NCBS researchers-led ten year ecological study on savannah-grasslands * NCBS to receive man-eater tiger's fecal samples for DNA tests * Uma Ramakrishnan gives INK Talk* The New Indian Express covers students' meet SCCS co-organized by NCBS, quotes Dean Bhalla* NCBS-Srishti collaboration encouraging science-art interactions highlighted by The Indian Express * PI Yamuna Krishnan chosen for Shanti Swarup Bhatnagar Award 2013 in Chemical Sciences category* The Economic Times covers NCBS research on endemic bird at ongoing SCCS meet* International conservation meet co-organized by NCBS begins on 25th September * The New Indian Express: "NCBS to work with foreign varsities"* NCBS among partners of MIT's new $25 million Center for Brains, Minds and Machines * NCBS-Cambridge and NCBS-RIKEN bio-pacts featured in The Telegraph * NCBS-RIKEN launch of joint research center featured in The Hindu* NCBS-RIKEN collaboration covered by Economic Times * NCBS-Cambridge launch of new Centre for Chemical Biology covered by Hindustan Times * Hindu Businessline covers DBT-RIKEN pact and its NCBS connection* Professor Obaid Siddiqi passes away * Nature paper co-authored by NCBS PI Venkadesan in BBC News* Anil Ananthaswamy wins Best Investigative Journalism Award* Associate Director of CBDR Siddharthan Chandran on TED* NCBS research on mosquito OBPs featured in The Hindu * BBC News covers Cardiff University-NCBS collaboration on tiger diversity* The Hindu mentions Vrinda Grover's talk at NCBS * 15th May: Deadline for applying for the NCBS Science Journalism course * Chattarji and team's study linking stress to forgetfulness covered in The Telegraph* Women in Science: Yamuna Krishnan and Vatsala Thirumalai feature in The Times of India* Satyajit Mayor talks about biological research in India in EMBO Reports* K. VijayRaghavan and Sumantra Chattarji quoted in Forbes India magazine* The New Indian Express quotes Sumantra Chattarji on autism and CBDR * Bert Holldobler talks at NCBS on 26th March at 6.30 pm* NCBS's Krushnamegh Kunte quoted on butterfly migration in The Hindu* NCBS affiliate Anil Ananthaswamy wins inaugural Physics Journalism award* Bangalore Bio-Cluster featured in Science Careers* Centre for Brain Development and Repair launched at InStem * The Hindu covers Dan Lieberman's NCBS talk * Padma Shri for K. VijayRaghavan * NCBS's Krushnamegh Kunte helps identify butterfly last sighted in 1903* NCBS among stakeholders of 'Science Gallery': Times of India* "This Mayor loves wearing different hats": Times of India* Infosys Prize 2012: Mayor quoted in The Hindu* NCBS's Satyajit Mayor wins 2012 Infosys prize*"India Inc's new bogey": Srinivasan writes in Down To Earth* PhD student Umesh Srinivasan and team write about the National Investment Board * NCBS Citizen Science programs featured in The Hindu* Earth Hero Award for research associate Nandini Velho * "Four leopards killed every week": Times of India article on wildlife student's thesis * The Hindu writes about the Nobel Prize winners' Bangalore connection with InStem* Cambrige-InStem tie-up draws huge DBT funds* NCBS adjunct faculty, affilates win prestigious Lasker Prize* NCBS, CNRS and Institut Curie sign joint agreement


text:
I can't believe it. I just cannot believe what I saw in my inbox. If it wasn't bad enough that the folks at Arrowhead Drive are trying to recruit season ticket holders the signature at the bottom of the page just is a smack in the face. I understand that this is their job, but COME ON, they could use a little more class.
First the title basically yelled at you. What, am I supposed to just jump out of my seat and grab the phone hoping the lines at Arrowhead Drive aren't busy:
2009 Season Ticket Deposits NOW!
Here's the gist of the email. I omitted the middle section (THE SIGNATURE IS NOT A JOKE). It's great that we have THE MOST EXCITING schedule in the NFL. Wow, we should feel priveleged. Gawd knows we need to have that GUARANTEED seat. I guarantee nose bleed seat purchasers can walk down and sit at the 50 after half time. This seasons opponenets are bad enough...next season will be worse if things are status quo in management.
Greetings from Arrowhead! Your Chiefs are set to take on the Tennessee Titans at Arrowhead Stadium, October 19th at noon. Tickets to this upcoming Arrowhead battle are currently available…If you have questions about special promotions or exciting new ticket offers, please contact ----------- directly at 816-920----. See below for the 2009 Season Ticket information:
With the 2008 season underway, it's time to GUARANTEE your spot in the "New Arrowhead" Stadium as a Kansas City Chiefs 2009 Season Ticket Holder. The Chiefs have the MOST EXCITING 2009 home schedule in all the NFL and your game day experience will be enhanced as you take advantage of the wider concourses, increased restrooms and concessions and other amenities that begin to open in the "New Arrowhead."
2009 Chiefs Home Opponents:
· Dallas Cowboys
· New York Giants
· Pittsburgh Steelers
· Denver Broncos
· San Diego Chargers
· Oakland Raiders
· Cleveland Browns
· Two Preseason Games TBD
· One AFC East Opponent
The best compliment one can receive is a Referral from a satisfied customer!


text:
The Monster of Florence
Deceptive Tactics
On June 19, 1982, a Saturday night, the killer struck again near Montespertoli, southwest of Florence.Ā A young couple, 22-year-old Paolo Mainardi and his girlfriend, 20-year-old Antonella Migliorini, were making love in a parking space near the Via Nuova Virgilio provincial roadway, when someone appeared out of the bushes and began shooting.Ā Both were struck by the initial barrage of gunfire and Antonella died almost immediately.Ā Even though Paolo was seriously injured, he was able start the car, turn on the headlights, and shift the vehicle into reverse.
Unfortunately the car ended up in a ditch and Paolo was unable to get it back out.Ā The killer wasted little time and quickly shot out the vehicles headlights, restoring the darkness and emptied his pistol into the two victims.Ā After turning off the engine, the keys were pulled from the ignition and thrown into the weeds.Ā Obviously disturbed by traffic in the area, the killer decided to skip the gruesome mutilation rites and fled the scene without even realizing that Paolo Mainardi was still alive.
Unfortunately for Paolo, he was not discovered until the following morning and died just hours later, without ever having regained consciousness.Ā Later the same morning, the assistant district attorney assigned to the case, Silvia Della Monica, gathered various reporters from the media in her office and asked them to spread a minor lie.Ā The keen assistant DA wanted the press to report that Paolo Mainardi was still alive when he arrived at the hospital, and that he had had time to give a description of the killer before he died.Ā All of the reporters agreed, and the information appeared in the afternoon paper.Ā Silvia Della Monica was hoping that the killer would become anxious and make a false move.
The assistant DAs gamble did make the killer nervous.Ā Following the release of the afternoon paper, one of the Red Cross emergency workers who had accompanied Paolo Mainardi to the hospital received two telephone calls from a person who first claimed to be with the DA's office and then changed his story, identifying himself as the murderer.Ā He wanted to know what the young man said before dying.Ā
A few days after the murder of Paolo Mainardi and Antonella Migliorini, a sergeant in the police force, Francesco Fiore, recalled the murder of Barbara Locci and Antonio Lo Bianco, committed in 1968 when he was assigned to Signa.Ā Francesco began to wonder if there was a connection with the crimes of the Monster.Ā On his insistence, the shells were compared and the tests revealed that the same weapon, a Beretta .22-caliber pistol, fired all the Winchester bullets, and that the shells all came from a single box of 50 bullets.Ā The pistol used by the Monster was the same weapon that killed Locci and Lo Bianco in 1968.
Analyzing the situation 14 years after the 1968 murders, it was immediately apparent that Stefano Mele, the husband of the murdered woman, could not have been the Monster of Florence since he was in jail in both 1974 and 1981.Ā At that point the investigators assumed that Mele had to have an accomplice -- someone who continued killing after he was imprisoned.Ā Regardless, Mele was still claiming his innocence and refused to cooperate with investigators.


text:
Follow Megan's blog and enter to win one of the following books (pre-orders). Winner will get print book if US or e-book (or Amazon gift card equivalent) for International readers.
Dare You To by Katie McGarry
Nantucket Blue by Leila Howland
Parallel by Lauren Miller
Transparent by Natalie Whipple
***If you would like to be featured for a Blogger Spotlight post or if you want to see previous blogs featured click HERE***
***Off Sides***
***Off Sides***
2 e-book copies of Off Sides (Nook
or Kindle format), open Internationally!
or Kindle format), open Internationally!
***The 5th Wave***
Penguin Teen/Putnam Juvenile is offering a copy of The 5th Wave by Rick Yancey! Enter in the rafflecopter below for your chance to win! (US only)
a Rafflecopter giveaway


text:
The writing is on the fence for the White House for the GOP: whites will be the minority of American voters in the future. And even before then, Presidential candidates need to represent the entire American populations, not just certain groups of voters…
via daily-infographic:
America's New Minority
America's New Minority
posted 01 March, 2013
Hi, my name is Matthew. I'm a Communications pro and Social Media geek in NYC. I blog, I tweet, I take pictures and make movies; therefore I am Matthew Hurst!
This is my microblog where I share internet memes and popular culture, with a healthy dose of irony; updated on a daily basis.
Follow on Twitter
Scaffold theme by Mike Harding.


text:
It can be a real pain for county officials when people are out driving on the road in bad conditions and end up abandoning their cars.
That keeps plow drivers from clearing roads of snow, slowing down the whole operation and delaying the opening of roads so that other motorists can travel freely.
Still, a new proposal before Madison County commissioners seems to go too far in penalizing those who drive during travel restrictions. The new ordinance would levy a fine of up to $1,000 on motorists who travel during the highest-level travel advisories. Such motorists could also spend time in jail.
Part of the problem with this proposal is it creates a need for great discretion on the part of law enforcement officers. Those who provide essential services are exempt from travel restrictions, but the range of purposes that might be considered essential, in layman's terms, is hard to define.
Would someone who is going to check on an elderly relative not be serving an essential need? How about someone whose boss demands that they show up at work? Is it not essential to this motorist to drive despite travel restrictions?
While it's understandable that county officials would like to motivate motorists to stay at home when travel restrictions are imposed, a traffic citation with a lower fine seems like just punishment. A $1,000 penalty and the threat of jail time are simply too much.


text:
Colombian Color is an online presence and referral service for Colombia: personal and business. ColombianColor offers a referral service for individuals and businesses who need an online presence. Colombian Color also offers creative consulting in the form of: New ideas for online marketing companies Data processing services International Contacts Photographic Solutions Location Independent solutions
BEAUTIFUL COLOMBIA HAS MANY HIGH QUALITY EXPORTS, E.G:http://www.indexmundi.com/colombia/exports_commodities.html Rusty-Re-incarnation, Park 93, Bogota https://www.cia.gov/library/publications/the-world-factbook/fields/2049.html
Colombian Color offers: Photos which Inspire Creative Marketing Consulting Skype: p.trader69 firstname.lastname@example.com Skype U.S.A # 1-206-317-1564
ENDORSEMENTS "Colombian Colors' photos and ideas were pivotal in our latest marketing endeavor." Ethacol Power Point Presentation Henry Cadavid- V.P. Ethacol email@example.com


text:
Number of ratings 5 / Average Grade: N/A Submit a correction
Dr Neufeld is the most brilliant, exuberating, and inspirational professor I have had in my four years at Brock. His passion for teaching fills the room and can captivate the mind of a student in any field. Large attention to detail, personal relativism, and overall ability to articulate any thought all are additions to his memorable teaching style
I thought this course would be boring and based on "school". It's not, it takes an existential theme..on your life. He is so good at capturing the audience's attention that it makes lecture enjoyable.
An education professor who still lectures and knows how. Amazing! And wonderfully refreshing. He actually teaches instead of having the students teach.
No Comments
More Education professors at Brock University


text:
Want another 20 free gems? Check your inbox and do the survey (regarding storyline)
downWorld asked me not to post survey codes anymore because it ruins player feedback. We want the game to improve! So go ahead, do the survey… it helps. And thank you ^_^
What do you guys think about the storyline?
Please leave a comment below. Thanks!


text:
The next time you visit the , take a moment to look at the tree that has just been planted in the Girl Scout Garden right outside the entrance door.
Awarded in a lottery to New Milford by the N.J. Shade Tree Federation, this white pine tree was grown from one of the seeds that flew aboard the Space Shuttle Columbia that launched from the Kennedy Space Center in Florida on April 4, 1997.
The white pine seeds were brought into space by astronaut Gregory Linteris on the 22nd flight of the Space Shuttle Columbia and the 83rd space shuttle mission.
Linteris, who grew up in Demarest and attended Northern Valley Regional High School and Princeton University, was given the seeds by the N.J. Forest Service's Community Forestry Program, in cooperation with the N.J. Community Forestry Council and the Demarest Shade Tree Commission, to take on the mission.
The space shuttle Columbia was the first of NASA's space shuttle programs and completed 27 missions before being destroyed upon re-entry on February 1, 2003 at the completion of its 28th mission. All seven crew members were killed.
Once the seeds were returned they were germinated at the N.J. Forest Services greenhouse in Jackson as part of the Heritage Tree Program.
Steve Perrone, Commissioner of New Milford's Shade Tree Commission, said that being awarded this tree is a great honor for the town of New Milford. "This tree is a part of history," Perrone said. "And now, so are we."
The commission is having a plaque made that will be placed in the garden alongside the tree.


text:
Why Iams?
Campaign Updates
Get Active
Donate Now
Boycott Iams
Join PETA's Activist Network
See Demo Photos
Return Iams Products
Send Iams a Special Delivery
Talk to Your Local Shelter
More Ways to Help
Become a Member
Brands Not Tested on Animals
Other Companion
Animal Food Issues
An Iams Gallery of Misery
The last three letters of his lab identification are "mas," thus his name. But his life is far from a celebration. PETA's investigator discovered that his ears had been allowed to reach a level of such extreme filth that they required medication. She noticed the problem only by giving Christmas hands-on attention which he had never previously received. His feet have developed sores from years of living on cement and slatted metal.
Fifi has been used in Iams studies for at least six years. She hides in the back of her cage constantly.
MadDog is frustrated by his life in a 3-foot-by-3-foot cage. He often pushes his food bowl onto the floor to get attention but it hasn't done any good. He has been caged for Iams metabolic studies for six years. His voice was taken from him surgically during PETA's investigation.
Maisy loves attention but rarely gets it. It's even harder now that she's been debarked and has no voice. Maisy has been caged since September 18, 1997.
Maxine hides in the back of her steel cage and in the gutter of her cement kennel. Maxine has trouble eating when she is locked in the metabolic cage. She was surgically debarked along with 18 other Iams dogs during PETA's investigation. Iams did nothing to stop Maxine or the others from losing their voices.
Mickey has spent almost her entire life in Iams metabolic studies. She becomes extremely depressed when taken from her cement kennel to be put into the steel metabolic cage.
No Name
This Iams dog has no name—only a laboratory identification number. She lives in a dark building with no access to the outdoors or natural light, along with approximately 100 other dogs. Because she has no resting board and is not removed from the cage during cleaning time, she often is forced to sit or lie on wet concrete. She is lonely, sweet, and depressed.
Sally is extremely timid. She was born on April 10, 1996, and has spent the last six years trying to sleep and walk on cold wide-slatted floors. Many dogs injure themselves when their legs become stuck in between the slats.
Click here to help Fifi
and the other Met dogs
by making a life-saving donation today!
Back to Top
Iams Continues Cruel Experiments on Animals
Update: Iams Stops Using Chicks in Tests!
We Want Empty Cages, Not Slightly Nicer Cages
Print This Page
E-Mail This Page
Subscribe to E-News
Copyright © 2014 PETA Read our full policy
About PETA
Donate Now
Privacy Policy
PETA Web Sites
PETA is a nonprofit, tax-exempt 501(c)(3) corporation.