text:
A scene not all that dissimilar than the founding of the AP.
Добро пожаловать Kommentors of da Arrowhead Pride, we are informing you very much of our pleasure in accepting most glorious appointment as OFFICIAL Arrowhead Pride Komment Ombudsman, Komment Wrangler, and all around Kommentkutioner.
What this mean for you, das Kommentor Ivan Six Pack?
(Or at least severely mocked by the PARADE with absurd pictures)
I. First and Foremost, A Numero Uno:
[in a Jack Bauer whisper yell]
When respect is given it must be returned.
Chris created this site and puts up quality content in the hopes of interesting you a complete stranger, don't waste his or other people's time with crap comments. While generally the AP is an angry mob Chris and the AP junta reserve the right to have the PARADE axe you comments should they cross this crap threshold.
But, with that in mind...
II. This IS Blogfrica.
If you've seen Lord of War or Blood Diamonds, this concept should be pretty easy. The internet and the AP is largely an unruly, anonymous den of iniquity, moral atrocities, and obscenity, we'll pretty much let anything go up to a point, after all this is Blogfrica... If you're offended by this sort of talk you probably shouldn't visit those places. Furthermore, while Chris tries to keep obscenity to minimum on the front page, the Komments section is like the Liberia of Blogfrica, we can't be responsible for you degenerates too...
III. Man, there are SOME limits.
We know we just said it's Blogfrica and all but there are certain things that cross the human being barrier. Like we don't really care if you want to use the suffix -kakke or generally push any PC barrier you like, but don't be stupid about it. Things that typically cross this line: defaming the dead, posting unwanted personal information, virulent racism, mocking the armed forces, and maybe some things that fall in the "too soon" category
IV. Be Funny, Do Not Be Unfunny.
Yeah, it's stolen from Deadspin, but it's true. This isn't Deadspin, you don't have to be funny or entertaining; well-informed or just enthusiastic are just fine and welcomed by Chris. But generally, if you're going to push the limits, attempt to be funny, or hurl insults at anyone or anything, don't be unfunny, if you don't know if you're funny you probably not and that's okay, just don't post it on the AP. WE WILL MOCK YOU. Don't think it's fair we decide what's funny and what's not? Well, why don't you go get intoxicated and encourage your good friend to create the most popular Chiefs site in the known universe, then you can call the shots over there.
That said...
V. Credibility trumps damn near everything.
Sure we reserve the right axe at will or even at beckon, but generally these Komments are yours - the reader's - and if a Kommentor builds up a solid rep we're not gonna axe it whether we like the Komment or not (See Rule I). It's unfortunate that the influx of Kommentors created the need for a Kommentkutioner, but most Kommenters that have been on the AP for a while have a solid rep for self-regulating.
NOW Zee Guidelines for Nu-Kommenters
Generally these all fall under Rule I so we didn't see a need to keep going, and as with any guideline there's certainly exceptions, but generally follow these practices and you won't get axed...or exkommentukated....
- It's just a blog, it's not real, don't get upset
- Don't post simple insults aimed at other Kommenters
- Don't type in all caps
- Don't Komment if you have no point (unless it's supposed to be all existential)
- If possible type like at least a semi-literate chimpanzee
- Don't put giant pictures in your signature line, or generally anything that when repeatedly viewed in a Komment section gets annoying.
- Don't abuse the exclamation mark
- If you type things that make you look stupid accept your mocking like a man (or a woman as the case may be)
- Don't insult Kommentors that may have been there a lot longer than you
Don't Repost Information - (an honest mistake is one thing, but three fanposts about some stupid talk radio rumor does nothing but piss the PARADE off because you're probably knocking some BS joke thread he started into the archives)
Generally, these are pretty good rules too
Alright, everyone pleased? No? Kommentkutioned! Back to the Anti-Government d*ck jokes in the comments...


text:
|Old vegetables in a new garden
|Wednesday, March 20, 2013 2:15 PM
By Kylee Baumle
My husband and I have had a vegetable garden ever since we've lived here, which is going on 36 years. Over the years, we've grown the usual fare; peas, green beans, carrots, radishes, lettuce, corn, spinach, beets, broccoli, but in the last eight years or so, I've tried to plant something a little different, just to keep it interesting.
One of the first years that I tried to get creative, I planted an assortment of purple vegetables. We're used to seeing green veggies, but imagine a garden full of purple or burgundy ones!
We had purple-podded beans (which turn green when you cook them), burgundy okra (beautiful plant and fruits, but we didn't eat them), red Chinese beans (a.k.a. yard-long beans), purple lettuce, and even burgundy sweet corn (just as tasty as yellow). It was a beautiful thing to behold.

subset: commoncrawl


text:
Rumors by Ricky Cadden on Tuesday December 23, 2008.
t-mobile dash · t-mobile · rumors · t-mobile news · wm news · smartphone news · ricky cadden
|Sponsored links, if any, appear in green.
A photo submitted to Boy Genius Report suggests that a new version of the T-Mobile Dash smartphone is landing in select stores, pending a full release. The new version is clad in an all-black color scheme, and does not seem to feature any new hardware updates.
Commenters at Boy Genius Report have suggested that the build quality of this new version is supposed to be improved over the previous silver version, though clearly those claims are unconfirmed.


text:
Mason Mills threw five touchdown passes as San Diego handed Butler its first Pioneer Football League defeat of the season 42-14 on Saturday.
Mills, the Toreros' career passing leader, was 26-of-36 for 407 yards as he went over the 10,000-yard mark. Sam Hoekstra had nine catches for 175 yards, including a 54-yard touchdown, to go over 2,000 career yards. Brandon White added two touchdown receptions.
The Toreros (5-3, 4-1), who had a nine-game winning streak snapped in a double-overtime loss to Dayton a week ago, left no doubt, rolling to a 35-0 lead before the Bulldogs (6-3, 4-1) scored their first touchdown on Matt Lancaster's 3-yard run with 15 seconds left in the first half.
Lancaster, who missed last week's game with concussion symptoms, was 24-of-41 passing for 251 yards, including a TD and interception.
Butler's defeat left four teams atop the Pioneer with 4-1 records.
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text:
Proprietary & Nonstandard Elements
The following elements are not actually deprecated. If something is
deprecated it means that it has, at some point, been defined in a standard
but was removed from a later version of the standard. However, none of the
elements below have ever been defined by any standards, but were rather
added on as 'features' by browser vendors. Some never caught on
nobr), while others are very
well supported to this day across a wide range of browsers
marquee). Regardless of
their level of support, their use is discouraged, wherever practically
possible, in favor of using elements that are part of a W3C-approved standard.


text:
Geographical coverage
ForestAction has reached almost one-third of the country's geographical area i.e., 50 districts covering all the ecological and development regions. Following Figure gives an indication of its coverage.
- Far Western: Achham, Baitadi, Dadeldhura, Kailali, Bajura.
- Mid Western: Banke, Bardiya, Dang, Dolpa, Kalikot, Surkhet, Mugu, Jumla.
- Western: Arghakanchi, Baglung, Gorkha, Kapilvastu, Kaski, Mustang, Nawalparasi, Palpa, Parvat, Pyuthan, Rupandehi, Syangja.
- Central: Chitwan, Dhanusha, Dolakha, Kathmandu, Kavre, Lalitpur, Parsa, Rasuwa, Sarlahi, Sindhuli, Sindhupalchowk, Solukhumbu, Makwanpur, Bara, Rautahat.
- Eastern: Dhankuta, Ilam, Jhapa, Khotang, Morang, Panchthar, Saptari, Siraha, Sunsari, Terathum.


text:
What are you hoping the Easter bunny will bring to your house? If it's breathing, there's something you and the bunny should know first. Bunnies and chicks look so cute in Easter baskets, but what happens the day after Easter and the day after that?
Dr. Ron Warner is not just an Epidemiologist at the Texas Tech Health Sciences Center, which means he studies how to control diseases, but he also happens to be a veterinarian. He says the first thing people tend to forget is it is almost impossible to house-train a bunny or a chicken. However, there are more serious reasons than that to keep these little treasures out of your household.
"The major risk that they present are Gastro Intestinal Diseases as a consequence of bacterial contamination either on the animal or in the environment where the animal resides and many children may not wash their hands appropriately and consequently can transfer the bacteria to their mouth and their GI track," said Dr. Ron Warner.
He adds that Salmonella poisoning is the most common offender. If you must buy one of these critters, he says at least ask the store several important questions. First, is the animal coming from an approved hatchery? Ask if any of the animals in the group have been ill and ask if there is a place in the store where kids can wash their hands before and after handling the animals, which he says should become routine practice if you end up buying one.
Another important question some people forget to ask themselves, where are we going to keep this chicken or bunny after the holiday? And don't forget that chickens grow up fast so buy a baby chick for Easter and you'll have an big chicken by Memorial Day.
5600 Avenue A
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text:
The wait is over! Download the BeerAdvocate app on iTunes or Google Play now.
Get 12 issues / year of BeerAdvocate magazine for only $9.99!
Space Needle Golden Anniversary 2012 Vintage IPA - Pike Pub & Brewery
Displayed for educational use only; do not reuse.
Ratings: 78 | Reviews: 20 | Display Reviews Only:
Reviews by jmarsh123:
3.25/5 rDev -16%
07-29-2013 21:12:13 | More by jmarsh123
More User Reviews:
North Carolina
4.23/5 rDev +9.3%
There is something about a classic Pacific NW IPA bursting with cascades,I just love em.Poured into an imperial nonic a deeply hazed burnt orange infused golden with a frothy sticky one finger white head that left a perfect ring of lace as it settled very slowly.Big grapefruit rind in the nose, it's fresh and really jumps out at ya,English malts provide some biscuit malt notes.Sharp grapefruit and grassy flavors over top of English malts wich are pretty big in their own right,just a well rounded resiny IPA.I may like this more than many but I just really like a big cascade hopped ipa,it's true to what I think an American IPA is,just my opinion.
01-22-2013 22:49:03 | More by oberon
3.75/5 rDev -3.1%
08-08-2013 15:00:44 | More by npala86
3.75/5 rDev -3.1%
05-01-2013 01:30:29 | More by warnerry
3.5/5 rDev -9.6%
06-29-2013 04:57:19 | More by Lazaro
3.68/5 rDev -4.9%
Thanks to 5000 for sending me this bottle.
The beer pours a hazy yellow-orange color with a white head. The aroma has a lot of floral notes, as well as some pine, orange and biscuit notes. The flavor is similar, with a lot of orange and resin notes from the hops, which are complimented by the biscuit malt. There is a low amount of bitterness. Medium mouthfeel and medium carbonation.
05-17-2012 04:47:47 | More by Mora2000
4/5 rDev +3.4%
06-09-2014 20:45:21 | More by HoppySeb
3.75/5 rDev -3.1%
08-17-2013 18:02:59 | More by InfernoBoss
4.03/5 rDev +4.1%
Had on tap at Pike. Review from notes.
A: Pours a very nice orange color with a one finger white head on top with great retention, lasting the majority of the time it took to drink the beer. Sudsy lacing formed down the sides.
S: Very nice hop aroma up front, lots of grass and tropical fruits, some grapefruit, pineapple, and lemon. Just a bit of bready malt in the middle, but the hops dominate the aroma.
T: Rather earthy, lots of grass and citrus fruit flavors including lemon and orange zest, as wells as some grapefruit. Just a touch of light caramel.
M: Medium bodied with medium carbonation. Slightly dry with a bit of a bitter finish.
O: Probably the best beer I have had from Pike thus far. Much bolder and fresher tasting, maybe it will come back at some point.
02-12-2013 05:42:58 | More by mdaschaf
3.75/5 rDev -3.1%
08-18-2012 23:53:05 | More by Aeromaximus
3.66/5 rDev -5.4%
Pike's 2012 Vintage IPA commemorates the Golden Anniversary of the Space Needle. But can it compare to Genesee's Golden Anniversary Ice?, or for that matter, the can GA Ice comes in? Only one way to find out!
22oz bottle into tapered pint glass. Beer pours a hazy golden yellow with moderate white head. Big C-hop aroma -- very West coast. Big C-hop flavor, too. Grapefruit and citrus peel through and through. Mouthfeel is pretty light, resulting in a pretty refreshing brew, despite serious IBUs.
The flavors here are really good but I prefer a bit more balance in an IPA.
05-04-2013 03:30:17 | More by hreb
3.75/5 rDev -3.1%
08-12-2012 20:36:27 | More by jmccraney
4.75/5 rDev +22.7%
04-07-2013 00:33:12 | More by jwluvsIPA
3.5/5 rDev -9.6%
05-15-2013 03:38:38 | More by GRG1313
4.5/5 rDev +16.3%
In a word, yum!
Served twice at the brew pub. This is a great IPA where the hops freshness and the bitterness trump the alcohol rating. You could almost session this beer, which has the chops of many a DIPA.
You just can't beat brewery fresh beer.
BTW, the waitress told me this is the one all the brewers drink, nudge nudge wink wink.
01-25-2013 02:54:27 | More by Monkeypaws
3.75/5 rDev -3.1%
05-31-2013 02:39:59 | More by buzzy
4/5 rDev +3.4%
01-07-2013 04:22:57 | More by hannaho
4/5 rDev +3.4%
01-13-2013 23:19:19 | More by Hopmodium
3/5 rDev -22.5%
07-24-2014 19:40:44 | More by JDeming
4.33/5 rDev +11.9%
Poured into a Black Raven pint glass. Pours a slightly cloudy medium orange amber with a nice one finger fine white head with good retention and lacing. Nice aroma of pineapple, sweet malt and herbal and piney hops. The great aroma is followed by taste, with a nice sweet malt body overlayed with aromatic herbal and piney hops, grapefruit citrus. Good bitter finish of herbal hops. A good medium body with pleasant creaminess. Very well done and one of the best non-imperial IPAs I've had. A nice surprise for a commemorative beer.
05-11-2012 03:24:56 | More by LiquidAmber
New Jersey
3.25/5 rDev -16%
04-15-2013 19:33:09 | More by rkcrozier
3.75/5 rDev -3.1%
12-18-2013 23:41:21 | More by dsshuck
Alberta (Canada)
4.25/5 rDev +9.8%
05-06-2013 01:13:36 | More by curtismontcalm
3.64/5 rDev -5.9%
Purchased at Safeway.
Appearance: Amber color, cloudy but think it's from the chill haze. Thin white head that leaves light lace.
Smell: Zesty, with citrus notes. Pine or cedar like wood scents too, very nice.
Taste: Citrus notes and slight hop bitterness. Pretty balanced with the mild sweetness. Aftertaste is just a touch heavy with citrus rind to me.
Mouthfeel: Nice meaty mouthfeel. Smooth, decent carbonation.
Overall: Very decent, just didn't like the aftertaste too much.
04-09-2013 06:47:27 | More by Braz
4.03/5 rDev +4.1%
On tap straight from the source. Pours a translucent golden color with a thin layer of head. Some lacing. Aromas of very citrusy hops. Floral as well. Taste is a nice amount of bitter citrus and floral hops. Extremely drinkable IPA. The floral hops come out more at the end. Nice bitter, floral finish. Mouthfeel is a bit thin, but helps with the drinkability. Too bad this is a one time brew. Overall, well crafted IPA. Worth having again if the chance should ever arise again.
06-16-2012 02:58:06 | More by PicoPapa
Space Needle Golden Anniversary 2012 Vintage IPA from Pike Pub & Brewery
87 out of 100 based on 78 ratings.


text:
Hats & Caps
Ladies' 1910 Legion Cap
Regular Price: $14.99
Special Price: $9.98Lightly distressed, with a soft and comfortable fit, this legion-style cap has the look and feel of an often-worn favorite. Contemporary styling includes Universal Emblem applique and "1910" screen-print at wearer's left-front. Also includes large Universal Emblem screen-print on back and "Boy Scouts of America" embroidery above the adjustable back strap. In Brown with tan applique and stitching. One size. Imported. Learn More
Ladies' Sequin BSA® Baseball Cap
Regular Price: $14.99
Special Price: $9.99Featuring the classic BSA® trademark logo embroidery and baseball-cap design elements (color-block styling, stitched brim, ventilation eyelets), this hat is made to suit any Scouting occasion. But upon closer inspection you'll see it offers ladies a little something extra. "BSA" lettering shows up front-and-center sporting a cleverly feminine, ombre sequined effect. Made of 100% cotton twill in Green and Ivory. One size. Imported. Learn More
Men's Crushable Wool Felt Outback Hat
Starting at:
$39.99A savvy outdoor choice, this handsome wide-brim hat is water-repellent and crushable - so you can roll it up or smash it down for transport, then snap it right back into shape! Made of 100% wool felt in Olive, featuring a brown, braided faux-leather band accented with three fleur-de-lis conches. A 3" brim enhances sun protection and comfort. Imported. Learn More
Panther Vision POWERCAP®$21.99At last! Here's the cold-weather version of a true Scouting favorite. Clever new design combines patent-pending Ultra Bright LED technology with a premium compression-fleece, beanie hat to provide you with the perfect hands-free flashlight for camping, fishing, hunting, walking, reading, auto and home repair, and so much more. Learn More


text:
I always hesitate to buy online and so I am writing this to let readers know that you can purchase this table with confidence. It is beautifully finished (I bought it in black) and appears to be constructed of all wood (pine) as described. The joints fit perfectly. No tools were needed to assemble it - which took less than 10 minutes! I actually ordered a pair to use as bed stands. These are 32 inches tall and so are perfect for my bed with its thick high mattress. I ordered on a Tuesday and they arrived on Friday. I can't say enough good things about this experience. I will look for other items by this company when/if I am in the market for occasional furniture.
This really complimented my existing night stand beautifully... I needed it in a small area, and it worked perfect.
good color, nice finish, sturdy, I would recommend this product to anyone
Great quality product, would definitely recommend, very sturdy and solid wood.
These are poorly made and cheap ,not steady on it's feet ,damaged parts, Overstock should have checked this product better, will return both
I purchased 2 of these night stands for one of my spare bedrooms, because of their size. They are not large so they don't overwhelm the room, yet they are tall enough to fit nicely on each side of a very tall bed. They were delivered quickly and were extremely easy to put together. I didn't even need my husband's help. They are sturdy and the quality is good. They are very affordable especially for a spare bedroom.
My bed is really high, so this night stand works perfectly. It was very easy to assemble too. I like how large the top it, if fits all my stuff.
Arrived in short time, sturdy package, address easy to read. Contents intact
Usually leaves our warehouse in 1-2 business days. *
Items must be returned in new or unused condition and contain all original materials included with the shipment. More details
FINAL SALE EXCLUSION: Items marked as FINAL SALE are not returnable unless the problem you experience is the result of our error.
This item cannot be shipped to Alaska or Hawaii.
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Our standard shipping method is ground shipping. We also offer expedited shipping for most items. Your final shipping cost and estimated delivery timeframe will be available at checkout.
Standard shipping details
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* For your safety, some orders go through our loss prevention department. If we select your order for this process, we will immediately notify you that there may be up to a 3-day delay on your order.
** Most Oversize orders are delivered within 1-4 weeks. Some orders may take 6 weeks to be delivered.


text:
October 25, 2004
Americus- Seconds after a masked man walks in the Flash Foods on Highway 49, he begins beating the 64-year-old cashier.
He's unarmed, but the weapons are his fist and his feet.
"Without stating this was a robbery or open the cash register, he automatically went to beating on the clerk that was on the floor, brought her down to the ground and continued to kick her," said Richard McCorkle, an investigator with Americus Police Department.
There are three men involved in this robbery. You can see them all on the store's surveillance video. The easiest to make out is wears dreadlocks and a goatee. But you don't see him again.
"It appears he went to the outside and was probably acting as a lookout on the outside of the store," McCorkle said.
Inside, it is the other cashier who offers to open the register drawer and give them money to stop the beating, all this, while the unmasked robber seems to discourage the other. But the masked man takes the money and makes the second cashier lie on the floor.
"Are you going to shoot me?" she says to him as she kneels on the ground.
But there's a not gun. Only more hitting and kicking.
Hours after the robbery, the Flash Foods is closed, the shocked employees inside refusing to talk.
Back at Americus Police Department, officers gather to watch the video closely, trying to recognize any of the three men.
"We've had several veteran officers look at it and we don't know them," McCorkle said.
But they'll show these scenes to every law enforcement officer in the state if they have to to put these men behind bars.
Both women, 64-year-old Emma Wainwright and 52-year-old Mary Ann Tissue, were released from Sumter Regional Hospital. Right now, police believe the men left the scene in a blue Volvo. There will be a reward for information that leads to the capture of the robbers.
posted at 10:58 p.m. by firstname.lastname@example.com
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EEO Report
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text:
Research Topics
Genomes and Genes
gastrointestinal transit
Summary: Passage of food (sometimes in the form of a test meal) through the gastrointestinal tract as measured in minutes or hours. The rate of passage through the intestine is an indicator of small bowel function.
Top Publications
Research Grants
Scientific Experts
Detail Information
Publications229 found, 100 shown here
- Moderation of lactulose-induced diarrhea by psyllium: effects on motility and fermentationN Washington
Division of Gastroenterology and Department of Surgery, Queen s Medical Centre, Nottingham, United Kingdom
Am J Clin Nutr 67:317-21. 1998..05). Psyllium delays gastric emptying, probably by increasing meal viscosity, and reduces the acceleration of colon transit, possibly by delaying the production of gaseous fermentation products...
- Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxativesJ Tack
Division of Gastroenterology, Department of Internal Medicine, University Hospital, Gasthuisberg, Herestraat 49, B 3000 Leuven, Belgium
Gut 58:357-65. 2009..To determine the efficacy, impact on quality of life (QOL) and safety of prucalopride, a selective, high-affinity 5-HT(4) receptor agonist, in patients with chronic constipation...
- Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation--a 12-week, randomized, double-blind, placebo-controlled studyE M M Quigley
Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
Aliment Pharmacol Ther 29:315-28. 2009..Chronic constipation may result in disabling symptoms, is often unsatisfactorily treated by laxatives and negatively impacts quality of life (QoL)...
- Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipationA Agrawal
Neurogastroenterology Unit, Translational Medicine GI Sciences, University of Manchester, UK
Aliment Pharmacol Ther 29:104-14. 2009..A sensation of abdominal swelling (bloating) and actual increase in girth (distension) are troublesome features of irritable bowel syndrome (IBS), which is more common in patients with constipation, especially those with delayed transit...
- Etiology of portal hypertension may influence gastrointestinal transitR Sadik
Division of Gastroenterology, Institute of Internal Medicine, Sahlgrenska University Hospital, University of Goteborg, Goteborg, Sweden
Scand J Gastroenterol 38:1039-44. 2003b>Gastrointestinal transit studies have shown contradictory results in patients with portal hypertension. We have studied gastric emptying. small-bowel transit and colonic transit in patients with portal hypertension...
- Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology and Motility SocietiesS S C Rao
Division of Gastroenterology Hepatology, University of Iowa Carver College of Medicine, Iowa City, IA 52242 1009, USA
Neurogastroenterol Motil 23:8-23. 2011..Assessment of regional and/or whole gut transit times can provide direct measurements and diagnostic information to explain the cause of symptoms, and plan therapy...
- Prucalopride, a systemic enterokinetic, for the treatment of constipationA V Emmanuel
St Mark s Hospital, Harrow, Middlesex, UK
Aliment Pharmacol Ther 16:1347-56. 2002..Laxatives are frequently ineffective in treating constipation. An alternative therapeutic approach is to target serotonin-4 receptors, which are involved in initiating peristalsis...
- Review article: bifidobacteria as probiotic agents -- physiological effects and clinical benefitsC Picard
Danone Vitapole, Centre de Recherche Daniel Carasso, Nutrivaleur, Palaiseau, France
Aliment Pharmacol Ther 22:495-512. 2005..Bifidobacteria may exert protective intestinal actions through various mechanisms, and represent promising advances in the fields of prophylaxis and therapy...
- Utility of hydrogen breath tests in diagnosis of small intestinal bacterial overgrowth in malabsorption syndrome and its relationship with oro-cecal transit timeUday C Ghoshal
Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
Indian J Gastroenterol 25:6-10. 2006..Quantitative culture of upper gut aspirate is used as a gold standard for the diagnosis of SIBO. Studies on diagnosis of SIBO using non-invasive hydrogen breath tests are contradictory...
- Agarwood induced laxative effects via acetylcholine receptors on loperamide-induced constipation in miceMamoru Kakino
Department of Biofunctional Evaluation, Molecular Pharmacology, Gifu Pharmaceutical University, Gifu, Japan
Biosci Biotechnol Biochem 74:1550-5. 2010..These findings indicate that EEAs exerted a laxative effect via acetylcholine receptors in the mouse constipation model...
- Ileal brake: neuropeptidergic control of intestinal transitGregg W Van Citters
Division of Gastroinestinal and Liver Diseases, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Curr Gastroenterol Rep 8:367-73. 2006..Fat is the most potent trigger of these transit control mechanisms. The integrated circuitry of gut peptides and neurons involved in transit control in response to nutrients is described in this review...
- Bloating and distension in irritable bowel syndrome: the role of gastrointestinal transitAnurag Agrawal
Neurogastroenterology Unit, Gastrointestinal Sciences, School of Translational Medicine, University of Manchester, Manchester, UK
Am J Gastroenterol 104:1998-2004. 2009..Because constipation is often associated with delayed gastrointestinal transit, this study aimed at establishing whether patients with delayed transit show more distension and bloating ..
- Role of small intestinal bacterial overgrowth and delayed gastrointestinal transit time in cirrhotic patients with minimal hepatic encephalopathyAnkur Gupta
Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
J Hepatol 53:849-55. 2010..This cross-sectional study was carried out to elucidate the role of bacterial overgrowth of the small intestine and delayed intestinal transit among patients with MHE...
- Dose-response effect of a beta3-adrenergic receptor agonist, solabegron, on gastrointestinal transit, bowel function, and somatostatin levels in healthApril B M Grudell
Center, Mayo Clinic, Rochester, MN 55905, USA
Am J Physiol Gastrointest Liver Physiol 294:G1114-9. 2008..Our aim was to explore the effects of a beta(3)-AR agonist, solabegron, on gastrointestinal transit, safety, bowel function, plasma somatostatin, and solabegron pharmacokinetics (PK) following single and ..
- Gastrointestinal transit and mucoadhesion of colloidal suspensions of Lycopersicon esculentum L. and Lotus tetragonolobus lectin-PLA microsphere conjugates in ratsM J Montisci
Laboratoire de Pharmacotechnie et Biopharmacie, UMR 8612, , , , France
Pharm Res 18:829-37. 2001..These results could be attributed both to unfavorable physicochemical characteristics of the conjugates and to premature adsorption of soluble mucin glycoproteins, preventing any further specific adhesion...
- [Colonic transit time in patient with liver cirrhosis]Young Hoon Kim
Department of Internal Medicine, Hanyang University College of Medicine, San 17, Haengdang dong, Seongdong Gu, Seoul 133 792, Korea
Korean J Gastroenterol 42:394-9. 2003..Thus, the authors investigated the differences of colonic transit time between cirrhotic patients and normal controls with attention to factors that affect this change...
- The pharmacological effects of Daikenchuto, a traditional herbal medicine, on delayed gastrointestinal transit in rat postoperative ileusYohei Tokita
Central Research Laboratory, Tsumura and Co, Ibaraki, Japan
J Pharmacol Sci 104:303-10. 2007..POI was induced by laparotomy with manipulation of the gastrointestine under anesthesia, and gastrointestinal transit was calculated by migration of Evans blue. Daikenchuto (270 - 2,700 mg/kg, p.o...
- Gastrointestinal transit, post-prandial lipaemia and satiety following 3 days high-fat diet in menM E Clegg
Faculty of Education and Health Sciences, University of Limerick, Castletroy, Limerick, Ireland, UK
Eur J Clin Nutr 65:240-6. 2011..To date, no studies have shown any alteration in GE following shorter HF diets. The aim of this study was to assess if an HF, high-energy diet of 3 days can adapt gastrointestinal (GI) transit, blood lipids and satiety...
- Prognosis of constipation: clinical factors and colonic transit timeF de Lorijn
Department of Paediatric Gastroenterology and Nutrition, Emma Children s Hospital Academic Medical Centre, Amsterdam, Netherlands
Arch Dis Child 89:723-7. 2004..Measurement of colonic transit time (CTT) is sometimes used in the evaluation of patients with chronic constipation...
- Normal gastrointestinal transit after colonic resection using epidural analgesia, enforced oral nutrition and laxativeL Basse
Department of Surgical Gastroenterology, Copenhagen University Hospital, Hvidovre, Denmark
Br J Surg 88:1498-500. 2001..The aim of this study was to assess the transit rate of the entire gastrointestinal tract after colonic resection with multimodal rehabilitation...
- Effect of mosapride on gastrointestinal transit time and diagnostic yield of capsule endoscopyWei Wei
Department of Gastroenterology, Renji Hospital, Shanghai Institute of Digestive Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China
J Gastroenterol Hepatol 22:1605-8. 2007..The aim of this study was to determine the effect of oral mosapride on gastrointestinal transit time and the diagnostic yield of CE.
- Modulation of gastric emptying and gastrointestinal transit in rats through intestinal cannabinoid CB(1) receptorsMarco Landi
Research Center Sanofi Midy, Sanofi Synthelabo, SPA, Via G B Piranesi 38, 20137 Milan, Italy
Eur J Pharmacol 450:77-83. 2002We studied the delay in gastric emptying and gastrointestinal transit induced by the cannabinoid receptor agonists (+)-WIN 55,212-2 (R(+)-[2,3-dihydro-5-methyl-3-[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazin-yl]-(1-naphthalenyl)..
- Development and application of an in vitro methodology to determine the transit tolerance of potentially probiotic Lactobacillus and Bifidobacterium species in the upper human gastrointestinal tractW P Charteris
SET Consultants Ltd, Douglas, Cork, Ireland
J Appl Microbiol 84:759-68. 1998An in vitro methodology which mimics in vivo human upper gastrointestinal transit was developed...
- Characterization of two models of drug-induced constipation in mice and evaluation of mustard oil in these modelsRyosuke Kojima
Drug Discovery Research, Astellas Pharma Inc, Tsukuba, Ibaraki, Japan
Pharmacology 84:227-33. 2009..These results indicate that clonidine- and loperamide-induced delays in colonic transit are models of atonic and spastic constipation, respectively, and that mustard oil may be effective on both types of constipation...
- The relationship between symptoms, body mass index, gastrointestinal transit and stool frequency in patients with irritable bowel syndromeRiadh Sadik
Department of Internal Medicine, Sahlgrenska University Hospital, Göteborg 41345, Sweden
Eur J Gastroenterol Hepatol 22:102-8. 2010..The aim of this prospective study was to characterize the relationships between symptoms in IBS, GI transit, as a measure of GI motility, and BMI...
- Effects of Velusetrag (TD-5108) on gastrointestinal transit and bowel function in health and pharmacokinetics in health and constipationM L Manini
Clinical Enteric Neuroscience Translational and Epidemiological Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Neurogastroenterol Motil 22:42-9, e7-8. 2010..We assessed effects of Velusetrag on gastrointestinal transit and compared its pharmacokinetics in healthy volunteers (HV) and chronic constipation (CC) patients...
- Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oilA A Izzo
Department of Experimental Pharmacology, University of Naples Federico II, via D Montesano 49, 80131 Naples, Italy
Br J Pharmacol 129:1627-32. 2000..p.) or intracerebroventricularly (i.c.v.) on upper gastrointestinal transit in control and in croton oil-treated mice...
- The herbal medicine, Dai-Kenchu-to, accelerates delayed gastrointestinal transit after the operation in ratsHiroyuki Fukuda
Department of Surgery, Duke University Medical Center, Durham, North Carolina 27705, USA
J Surg Res 131:290-5. 2006..Dai-Kenchu-to (DKT), an herbal medicine, has been used for treating adhesive bowel obstruction in Japan. We studied whether DKT improves delayed GI transit after the operation, with or without morphine administration in rats...
- Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balanceJ McCarthy
Department of Medicine, University College Cork, National University of Ireland, Cork, Ireland
Gut 52:975-80. 2003..Prophylactic efficacy against colitis following lactobacillus consumption in interleukin 10 (IL-10) knockout (KO) mice has been reported. Whether this applies equally to other probiotic strains is unknown, and the mechanism is unclear...
- Effects of intravenous fructose on gastric emptying and antropyloroduodenal motility in healthy subjectsJulie E Stevens
University of Adelaide, Royal Adelaide Hospital, SA, Australia
Am J Physiol Gastrointest Liver Physiol 297:G1274-80. 2009..003) compared with fructose and saline (P = NS for both) infusions. In conclusion, iv fructose slows GE and modulates gastric motility in healthy subjects, and the magnitude of slowing of GE is comparable to that induced by iv glucose...
- Gastrointestinal transit of solid radiopaque markers in large and giant breed growing dogsM Weber
Laboratory of Nutrition and Endocrinology, National Veterinary School of Nantes, BP 40706, 44307 Nantes Cedex 3, France
J Anim Physiol Anim Nutr (Berl) 85:242-50. 2001..These could explained why digestive function and sensitivity could be different in dogs from different sizes and breeds...
- Assessment of the relationship between body weight and gastrointestinal transit times measured by use of a wireless motility capsule system in dogsCarol S Boillat
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA
Am J Vet Res 71:898-902. 2010To assess the relationship between body weight and gastrointestinal transit times measured by use of a wireless motility capsule (WMC) system in healthy dogs.
- Endothelin ETA receptor blockade potentiates morphine analgesia but does not affect gastrointestinal transit in miceGeorge A Matwyshyn
Department of Biopharmaceutical Sciences M C 865, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA
Eur J Pharmacol 543:48-53. 2006..BMS182874, and endothelin ET(B) receptor agonist, IRL1620, on morphine analgesia and changes in gastrointestinal transit in male Swiss Webster mice. Results indicate that morphine (6 mg/kg, s.c...
- Gastro intestinal tracking and gastric emptying of solid dosage forms in rats using X-ray imagingSigal Saphier
The Department of Organic Chemistry, Israel Institute for Biological Research, Ness Ziona, Israel
Int J Pharm 388:190-5. 2010The aim of this research was to study the gastrointestinal transit and gastric emptying of non-disintegrating solid dosage forms in rats using X-ray imaging...
- Abatement of morphine-induced slowing in gastrointestinal transit by Dai-kenchu-to, a traditional Japanese herbal medicineTomonori Nakamura
Laboratory of Molecular Pharmacology and Pharmacotherapeutics, Graduate School of Pharmaceutical Sciences, Chiba University, Japan
Jpn J Pharmacol 88:217-21. 2002..relieve pain, effects of Dai-kenchu-to (DKT), a traditional Japanese herbal medicine (Kampo medicine), on gastrointestinal transit in mice or on the isolated guinea pig ileum were studied in special reference to morphine...
- A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea-predominant irritable bowel syndromeH J Kim
Clinical Enteric Neuroscience Translational and Epidemiological Research Program, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Aliment Pharmacol Ther 17:895-904. 2003To investigate the effects of a probiotic formulation, VSL#3, on gastrointestinal transit and symptoms of patients with Rome II irritable bowel syndrome with predominant diarrhoea.
- Characterizing gastrointestinal transit time in four lemur species using barium-impregnated polyethylene spheres (BIPS)J L Campbell
Interdepartmental Nutrition Program, Department of Animal Science, North Carolina State University, Raleigh, North Carolina, USA
Am J Primatol 64:309-21. 2004..The flow of BIPS did not differ for VV and EF. These data reveal new information in addition to the total tract transit time, and complement existing knowledge regarding anatomy and diet...
- Evaluation of absorption kinetics of orally administered theophylline in rats based on gastrointestinal transit monitoring by gamma scintigraphyS Haruta
Department of Hospital Pharmacy, Central Research Laboratories, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, Miyazaki 889-1692, Japan
J Pharm Sci 90:464-73. 2001..Analysis using GI transit-absorption model and gamma scintigraphic technique made it possible to estimate the variable absorption kinetics regulated by GI transit with huge variability...
- Measurement of gastrointestinal transitHenry C Lin
Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
Dig Dis Sci 50:989-1004. 2005..As we make progress in our understanding of the pathophysiology of transit disorders, the clinical usefulness of these diagnostic tests will be further enhanced...
- Oral modified-release formulations in motion: the relationship between gastrointestinal transit and drug absorptionFelipe J O Varum
The School of Pharmacy, University of London, 29 39 Brunswick Square, London WC1N 1AX, United Kingdom
Int J Pharm 395:26-36. 2010..This is an oversimplification and in this review we discuss the effect of the highly variable gastrointestinal transit on the bioperformance of multiple-unit dosage forms, relative to their single-unit counterparts...
- Gastrointestinal transit time of nondisintegrating radio-opaque pellets in suckling and recently weaned pigletsV Snoeck
Laboratory of Veterinary Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
J Control Release 94:143-53. 2004..These data are of crucial importance in the design of enteric-coated formulations for oral administration of vaccines and therapeutics to young piglets and for human research using the pig model...
- Effects of fasting on evaluation of gastrointestinal transit with charcoal mealS W Mittelstadt
Drug Safety Assessment, Procter and Gamble Pharmaceuticals, Miami Valley Innovation Center, Cincinnati, OH 45252, USA
J Pharmacol Toxicol Methods 52:154-8. 2005At the present time, most studies investigating gastrointestinal transit time with charcoal are conducted in fasted rats...
- Model of rapid gastrointestinal transit in dogs: effects of muscarinic antagonists and a nitric oxide synthase inhibitorT Chiba
Division of Gastroenterology, Mayo Clinic and Mayo Foundation, Rochester, MA 55905, USA
Neurogastroenterol Motil 14:535-41. 2002Our aims were to establish a canine model of rapid gastrointestinal transit, and to test the effects of muscarinic receptor antagonists (atropine, pirenzepine, AF-DX116, and darifenacin), and an NOS inhibitor, L-nitro-N-arginine (L-NNA) ..
- Relative efficacy of some prokinetic drugs in morphine-induced gastrointestinal transit delay in miceA D Suchitra
Department of Pharmacology, JIPMER, Pondicherry 605006, India
World J Gastroenterol 9:779-83. 2003..To study the relative efficacy of cisapride, metoclopramide, domperidone, erythromycin and mosapride on gastric emptying (GE) and small intestinal transit (SIT) in morphine treated mice...
- Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosisEvangelos Kalaitzakis
Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Clin Gastroenterol Hepatol 7:346-52. 2009....
- Gastric transit and small intestinal transit time and motility assessed by a magnet tracking systemJonas Worsøe
Department of Surgery P, Aarhus University Hospital, Aarhus, Denmark
BMC Gastroenterol 11:145. 2011..Tracking System MTS-1 (Motilis, Lausanne, Switzerland) is an easy and minimally-invasive method to assess gastrointestinal transit. The aim was to test the validity of MTS-1 for assessment of gastric transit time and small intestinal ..
- Response to a behavioural treatment, biofeedback, in constipated patients is associated with improved gut transit and autonomic innervationA V Emmanuel
St Mark's Hospital, Northwick Park, Watford Road, Harrow, Middlesex HA1 3UJ, UK
Gut 49:214-9. 2001..Successful outcome after biofeedback treatment is associated with improved activity of the direct cerebral innervation to the gut and improved gut transit. This effect is gut specific; cardiovascular autonomic reflexes were not altered...
- Effect of bowel cleansing on colonic transit in constipation due to slow transit or evacuation disorderC E J Sloots
Department of Gastroenterology of the Vrije Universiteit Medical Centre, Amsterdam, The Netherlands
Neurogastroenterol Motil 14:55-61. 2002..However, because in an infrequent defecation pattern, the influence of faecal impaction is considerable, CTT should be applied with care for critical clinical decisions in the treatment of constipation...
- Involvement of mu-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7-hydroxymitragynine, isolated from Thai herbal medicine Mitragyna speciosaKenjiro Matsumoto
Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Josai International University, 1 Gumyo, Togane, Chiba 283 8555, Japan
Eur J Pharmacol 549:63-70. 2006..In the present study, we investigated the mechanism of antinociception and the inhibitory effect on gastrointestinal transit of 7-hydroxymitragynine, and compared its effects with those of morphine...
- Effect of centrally administered apelin-13 on gastric emptying and gastrointestinal transit in miceShuang Yu Lv
Institute of Biochemistry and Molecular Biology, School of Life Science, Lanzhou University, 222 Tian Shui South Road, Lanzhou 730000, PR China
Peptides 32:978-82. 2011..The present study was designed to investigate the effect of central apelin-13 on gastric emptying and gastrointestinal transit in mice. Intracerebroventricular (i.c.v...
- The effect of polyethylene glycol 400 on gastrointestinal transit: implications for the formulation of poorly-water soluble drugsA W Basit
Department of Pharmaceutics, The School of Pharmacy, University of London, UK
Pharm Res 18:1146-50. 2001..a pharmaceutical excipient frequently employed to enhance the solubility and bioavailability of poorly water-soluble drugs, on the gastrointestinal transit of liquid and pellet preparations in human subjects using gamma scintigraphy.
- Pharmacodynamic effects of a novel prokinetic 5-HT receptor agonist, ATI-7505, in humansM Camilleri
Department of Health Sciences Research, Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Neurogastroenterol Motil 19:30-8. 2007..056) with the 10 and 20 mg t.i.d. doses. No safety issues were identified. ATI-7505 accelerates overall colonic transit and tends to accelerate GE and AC emptying and loosen stool consistency...
- Slow transit constipation: a disorder of pelvic autonomic nerves?C H Knowles
Academic Department of Surgery, St Bartholomew s and the Royal London School of Medicine and Dentistry, Whitechapel, UK
Dig Dis Sci 46:389-401. 2001..We further present evidence for possible pathogenetic mechanisms underlying pelvic autonomic neuropathy in chronic idiopathic STC...
- Omeprazole-induced slowing of gastrointestinal transit in mice can be countered with tegaserodAlan Cowan
Department of Pharmacology, Temple University School of Medicine, 3420 N Broad Street, Philadelphia, PA 19140, USA
Eur J Pharmacol 517:127-31. 2005..These results show that omeprazole reduces aboral transit of luminal contents through the stomach and small bowel of mice and that this delay is reversed by tegaserod...
- The effect of different dosages of guar gum on gastric emptying and small intestinal transit of a consumed semisolid mealM A van Nieuwenhoven
Department of Gastroenterology, Maastricht University, The Netherlands
J Am Coll Nutr 20:87-91. 2001There is no consensus about the effect of guar gum supplementation on gastrointestinal transit. It has been suggested that guar gum slows gastric emptying and intestinal transit, thus inducing an increased feeling of satiety.
- Tropical sprue is associated with contamination of small bowel with aerobic bacteria and reversible prolongation of orocecal transit timeUday C Ghoshal
Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
J Gastroenterol Hepatol 18:540-7. 2003..In tropical sprue (TS), response to antibiotics may suggest a role for bacterial contamination of the small bowel, which is known in diseases with prolonged orocecal transit time (OCTT)...
- Summary of probiotic activities of Bifidobacterium lactis HN019Mary Ellen Sanders
Dairy and Food Culture Technologies, 7119 S Glencoe Ct, Centennial, CO 80122, USA
J Clin Gastroenterol 40:776-83. 2006..HN019 is a well-characterized probiotic strain with documented probiotic effects of meaningful magnitude especially in the area of immune system modulation...
- Do stool form and frequency correlate with whole-gut and colonic transit? Results from a multicenter study in constipated individuals and healthy controlsRichard J Saad
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
Am J Gastroenterol 105:403-11. 2010..The aim of this study was to assess the correlation between stool characteristics (form and frequency) and gut transit in constipated and healthy adults...
- Capsule endoscopy for the evaluation of patients with chronic abdominal painE Bardan
Department of Gastroenterology, Chaim Sheba Medical Center and Tel Aviv University, Sackler School of Medicine, Israel
Endoscopy 35:688-9. 2003..The aim of our study was to determine the role of capsule endoscopy in the evaluation of patients with unexplained chronic abdominal pain...
- Factor analysis identifies subgroups of constipationPhilip G Dinning
Department of Gastroenterology, St George Hospital, University of New South Wales, Kogarah, NSW 2217, Australia
World J Gastroenterol 17:1468-74. 2011..To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction...
- Functional defecation disorder as a clinical subgroup of chronic constipation: analysis of symptoms and physiological parametersMark T Eltringham
Wansbeck General Hospital, Ashington, Northumberland, UK
Scand J Gastroenterol 43:262-9. 2008..The aim of this study was to use cluster analysis and factor analysis of defecatory symptoms and physiological parameters to look for evidence of subgroups in patients with functional constipation...
- Error analysis of classic colonic transit time estimatesM Bouchoucha
Hopital Laennec, Laboratory of Digestive Physiology, 75007 Paris, France
Am J Physiol Gastrointest Liver Physiol 279:G520-7. 2000..The relative error could easily reach 100% independent of the site of colonic transit delay. The normal values of total CTT are then 44.3+/-29.3 instead of 30.1+/-23.6 h for males and 68.2+/-54.4 instead of 47.1+/-28.2 h for females...
- A new tactic to treat postprandial hyperlipidemia in diabetic rats with gastroparesis by improving gastrointestinal transitWeidong Xie
Institute of Medicinal Plant, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China
Eur J Pharmacol 510:113-20. 2005Improvement of gastrointestinal transit was thought to be a new tactic to treat postprandial hypertriglyceridemia in diabetic individuals with gastroparesis...
- Prostanoid production via COX-2 as a causative mechanism of rodent postoperative ileusN T Schwarz
Department of Medicine Gastroenterology, University of Pittsburgh Medical Center, 3550 Terrace Street, Pittsburgh, PA 15261, USA
Gastroenterology 121:1354-71. 2001..This study demonstrates a significant role for cyclooxygenase (COX)-2 and prostanoid production as mechanisms for surgically induced postoperative ileus...
- Prolonged gastrointestinal transit in a patient with a glucagon-like peptide (GLP)-1- and -2-producing neuroendocrine tumorPatricia L Brubaker
Departments of Physiology, University of Toronto, Room 3366 Medical Sciences Building, 1 King s College Circle, Toronto, Ontario M5S 1A8, Canada
J Clin Endocrinol Metab 87:3078-83. 2002..two of the intestinal proglucagon-derived peptides, glucagon-like peptide (GLP)-1 and -2, and delayed gastrointestinal transit, was characterized in a patient with a neuroendocrine proglucagon-derived peptide tumor...
- Influence of age and body size on gastrointestinal transit time of radiopaque markers in healthy dogsMickaël P Weber
Laboratory of Nutrition and Endocrinology, National Veterinary School of Nantes, France
Am J Vet Res 63:677-82. 2002....
- Selective jejunal manipulation causes postoperative pan-enteric inflammation and dysmotilityNicolas T Schwarz
Chirurgische Universitätsklinik der Friedrich Wilhelms Universität, Bonn, Germany
Gastroenterology 126:159-69. 2004..The current objective was to investigate pan-enteric inflammatory molecular and functional motility alterations of the muscularis from the unmanipulated stomach and colon initiated by selective jejunal manipulation...
- Effect of N-methyl-d-aspartate receptor blockade on neuronal plasticity and gastrointestinal transit delay induced by ischemia/reperfusion in ratsF Calcina
CURE Digestive Diseases Research Center, Division of Digestive Diseases, Building 115, Room 224, Veterans Administration Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
Neuroscience 134:39-49. 2005..The aims of this study were to investigate the effect of intestinal ischemia on gastrointestinal transit and on the expression of enteric transmitters in the rat, and whether the glutamate N-methyl-d-aspartate ..
- Capsule endoscopy: improving transit time and image viewZvi Fireman
Department of Gastroenterology, Hillel Yaffe, Hadera, Israel
World J Gastroenterol 11:5863-6. 2005..To evaluate the effect of various methods of small bowel preparation on the transit time and the quality of visualization of the entire small bowel mucosa...
- Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteersMichael Camilleri
Clinical Enteric Neuroscience Translational and Epidemiological Research Group, Mayo Clinic, Charlton 8 110, 200 First Street SW, Rochester, MN 55905, USA
Am J Physiol Gastrointest Liver Physiol 290:G942-7. 2006..Thus the ClC-2 activator lubiprostone accelerates small intestinal and colonic transit, which confers potential in the treatment of constipation...
- Colonic response to food in constipationMichel Bouchoucha
Laboratoire de Physiologie Digestive, Hopital Broussais, Universite Paris V, 96 rue Didot, 75014 Paris, France
Int J Colorectal Dis 21:826-33. 2006..Colonic response to food is possibly abnormal in constipation...
- Effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopyWai K Leung
Department of Medicine and Therapeutics, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, Hong Kong, China
World J Gastroenterol 11:4865-8. 2005..To determine the effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopy...
- Survival of lactococci during passage through mouse digestive tractHiromi Kimoto
Department of Animal Products, National Institute of Livestock and Grassland Science, Tsukuba Norin Danchi, Ibaraki, Japan
Can J Microbiol 49:707-11. 2003..If administered daily, viable strain N7 may exist continuously in the intestine. The effect of strain N7 on intestinal microbial balance and on animal health will be the subject of a further study...
- Escin: inhibiting inflammation and promoting gastrointestinal transit to attenuate formation of postoperative adhesionsFenghua Fu
Department of Pharmacology, School of Pharmacy, Yantai University, Yantai, P R, 264005, China
World J Surg 29:1614-20; discussion 1621-2. 2005..acid in a mouse model of acute inflammation, granuloma formation in a subchronic inflammatory rat model, gastrointestinal transit in rats with intestinal paralysis, intestinal motility in postoperative patients, and postoperative ..
- Comparative evaluation of gastrointestinal transit and immune response between laparoscopic and open gastrectomy in a porcine modelKazuki Ueda
Division of Laparoscopic and Bariatric Surgery, Department of Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, NY 10021, USA
J Gastrointest Surg 10:39-45. 2006..Adhesion formation was significantly less in the lap group. We concluded that laparoscopic gastrectomy resulted in faster bowel recovery and less immune suppression...
- Gastrointestinal transit, release and plasma pharmacokinetics of a new oral budesonide formulationM Brunner
Department of Clinical Pharmacology, Division of Clinical Pharmacokinetics, Medical University of Vienna, Vienna, Austria
Br J Clin Pharmacol 61:31-8. 2006The aims of the study were to: (1) evaluate the gastrointestinal transit, release and absorption of budesonide from tablets with a new multimatrix formulation (MMX) designed to release the drug throughout the whole colon, and (2) assess ..
- Nonadditive interactions between animal and plant diet items in an omnivorous freshwater turtle Trachemys scriptaSarah S Bouchard
Department of Zoology, University of Florida, Gainesville, FL 32611, USA
Comp Biochem Physiol B Biochem Mol Biol 144:77-85. 2006..These apparent nonadditive interactions may be due to differences in transit time of duckweed and shrimp. We believe this is the first evidence of two diet items producing opposing nonadditive effects when fed in different ratios...
- Biofeedback is superior to laxatives for normal transit constipation due to pelvic floor dyssynergiaGiuseppe Chiarioni
Gastrointestinal Rehabilitation Division, Valeggio sul Mincio Hospital, Azienda Ospedaliera and University of Verona, Verona, Italy
Gastroenterology 130:657-64. 2006..The aim was to compare biofeedback to laxatives plus education...
- Effect of alvimopan and codeine on gastrointestinal transit: a randomized controlled studyJonathan Gonenne
Clinical Enteric Neuroscience Translational and Epidemiological Research Program, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Clin Gastroenterol Hepatol 3:784-91. 2005..Our aim was to evaluate the ability of a peripheral mu-opioid antagonist, alvimopan, to reverse the effect of codeine on gastric, small-bowel, and colonic transit time in healthy volunteers...
- Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated ratsRonald Mathison
Gastrointestinal Research Group, Department of Physiology and Biophysics, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
Br J Pharmacol 142:1247-54. 2004..In this study, we examined whether CB(2) receptor activation is involved in the regulation of gastrointestinal transit in rats...
- Complete small-bowel transit in patients undergoing capsule endoscopy: determining factors and improvement with metoclopramideWarwick Selby
AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, Australia
Gastrointest Endosc 61:80-5. 2005..Passage of the capsule endoscope to the colon occurs in only approximately three quarters of patients. This study assessed factors that might influence the completeness of small-bowel transit, including orally administered metoclopramide...
- In vitro assessment of the upper gastrointestinal tolerance of potential probiotic dairy propionibacteriaYang Huang
School of Applied Sciences, The University of Newcastle, Ourimbah, NSW 2258, Australia
Int J Food Microbiol 91:253-60. 2004....
- Oro-caecal transit time and intra-luminal pH in cystic fibrosis patients with distal intestinal obstruction syndromeA M Dalzell
Royal Liverpool Children s Hospital, Alder Hey, Liverpool, UK
Acta Univ Carol Med (Praha) 36:159-60. 1990..The prolonged oro-caecal transit time observed in cystic fibrosis patients with DIOS may contribute to the syndrome, however intraluminal pH is unlikely to be a factor in the aetiology of DIOS...
- The effect of mosapride citrate on proximal and distal colonic motor function in the guinea-pig in vitroH S Kim
Department of Internal Medicine, Yonsei Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea
Neurogastroenterol Motil 20:169-76. 2008..The different distribution of neuronal and muscular 5-HT(4) receptors may support these findings. Therefore, mosapride may be a useful alternative to tegaserod and cisapride for constipation...
- Tegaserod, a 5-HT4 receptor partial agonist, accelerates gastric emptying and gastrointestinal transit in healthy male subjectsL Degen
Division of Gastroenterology, University Hospital, Basel, Switzerland
Aliment Pharmacol Ther 15:1745-51. 2001..Tegaserod can act as a promotile agent throughout the gastrointestinal tract...
- Ghrelin improves delayed gastrointestinal transit in alloxan-induced diabetic miceWen Cai Qiu
Department of General Surgery, The Affiliated Sixth Hospital of Medical School, Shanghai Jiaotong University, Shanghai 200233, China
World J Gastroenterol 14:2572-7. 2008To investigate the effects of ghrelin on delayed gastrointestinal transit in alloxan-induced diabetic mice.
- Bifidobacterium animalis strain DN-173 010 shortens the colonic transit time in healthy women: a double-blind, randomized, controlled studyP Marteau
Gastroenterology Department, European Hospital Georges Pompidou, Paris, France
Aliment Pharmacol Ther 16:587-93. 2002..A previous study has suggested that Bifidobacterium animalis DN-173 010 shortens the colonic transit time in women...
- Clinical trial: effectiveness of chewing-gum in accelerating capsule endoscopy transit time--a prospective randomized, controlled pilot studyP Apostolopoulos
Department of Gastroenterology, NIMTS Hospital, Athens, Greece
Aliment Pharmacol Ther 28:405-11. 2008..Capsule endoscopy (CE) fails to reach the caecum in approximately 20% of patients. Data suggest that chewing-gum, simulating sham feeding, provokes the cephalic phase of gastrointestinal (GI) motor response and may increase GI motility...
- The effect of low-dose erythromycin on whole gastrointestinal transit time of preterm infantsC Costalos
Department of Neonatal Medicine, Alexandra General Hospital Athens, 130 Artemidos Str, Paleo Faliro 17562, Greece
Early Hum Dev 65:91-6. 2001The aim of the study was to determine the effect of a low oral dose of erythromycin on whole gastrointestinal transit time [WGTT]. Erythromycin [EM] [1...
- Effect of vanilloid drugs on gastrointestinal transit in miceA A Izzo
Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy
Br J Pharmacol 132:1411-6. 2001..The effect of piperine involves capsaicin-sensitive neurones, but not vanilloid receptors, while the effect of anandamide involves cannabinoid CB(1), but not vanilloid receptors...
- Hydrolysed protein accelerates the gastrointestinal transport of formula in preterm infantsW A Mihatsch
Department of Pediatrics, University of Ulm, Germany
Acta Paediatr 90:196-8. 2001..The present trial investigated whether a protein hydrolysate formula reduces the gastrointestinal transit time in preterm infants...
- Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colonP B Jeppesen
Department of Medicine, Section of Gastroenterology, Rigshospitalet, University Hospital of Copenhagen, Denmark
Gastroenterology 120:806-15. 2001..5 kg/day) and energy (>2.3 MJ/day) and no postprandial secretion of GLP-2...
- Acylated oleanane-type triterpene saponins with acceleration of gastrointestinal transit and inhibitory effect on pancreatic lipase from flower buds of chinese tea plant (Camellia sinensis)Masayuki Yoshikawa
Kyoto Pharmaceutical University, Misasagi, Yamashina ku, Kyoto 607 8412, Japan
Chem Biodivers 6:903-15. 2009..O. KUNTZE; Fujian Province) were found to exhibit accelerating effects on gastrointestinal transit in mice and inhibitory effects against pancreatic lipase...
- Actions of prolonged ghrelin infusion on gastrointestinal transit and glucose homeostasis in humansY Falkén
Division of Surgery, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institute, SE 182 88 Stockholm, Sweden
Neurogastroenterol Motil 22:e192-200. 2010..The aim of this study was to evaluate effects of intravenous ghrelin on gastrointestinal motility and glucose homeostasis during a 6-h infusion in humans...
- Role of progesterone signaling in the regulation of G-protein levels in female chronic constipationZuo Liang Xiao
Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903, USA
Gastroenterology 128:667-75. 2005..The cause and mechanisms responsible for this syndrome are unknown. Progesterone has been suggested as a possible contributing factor. Our aim was to investigate the site and mechanisms responsible for this colonic motility disorder...
- Altered transit and bacterial overgrowth in the cystic fibrosis mouse small intestineRobert C De Lisle
Department of Anatomy and Cell Biology, University of Kansas School of Medicine, Kansas City, KS 66160, USA
Am J Physiol Gastrointest Liver Physiol 293:G104-11. 2007..In conclusion, small intestinal transit was significantly slower in CF mice, and this is likely a major factor in SIBO in CF...
- mu-Opioid receptor-knockout mice: the role of mu-opioid receptor in gastrointestinal transitS Roy
Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Brain Res Mol Brain Res 56:281-3. 1998The role of mu-opioid receptor in gastrointestinal transit was investigated using mu-opioid receptor knockout mice (MOR-KO)...
- Development of tolerance to the inhibitory effect of loperamide on gastrointestinal transit in miceKoichi Tan-No
Department of Pharmacology, Tohoku Pharmaceutical University, 4 4 1 Komatsushima Aoba ku, Sendai 981 8558, Japan
Eur J Pharm Sci 20:357-63. 2003..loperamide, a peripheral mu-opioid receptor agonist and well-recognized antidiarrheal agent, on mouse gastrointestinal transit was compared with that of morphine in order to examine the development of tolerance to mu-opioid receptor ..
- Effects of laxative and N-acetylcysteine on mucus accumulation, bacterial load, transit, and inflammation in the cystic fibrosis mouse small intestineRobert C De Lisle
Anatomy and Cell Biology, University of Kansas School of Medicine, Kansas City, KS 66160, USA
Am J Physiol Gastrointest Liver Physiol 293:G577-84. 2007..These results suggest that both mucus accumulation and slowed interdigestive small intestinal transit contribute to SIBO in the CF intestine...
- Opioid-induced bowel dysfunction: pathophysiology and potential new therapiesAndrea Kurz
Department of Anesthesiology, Outcomes Research Institute, Washington University School of Medicine, St Louis, Missouri, USA
Drugs 63:649-71. 2003..In addition, recent clinical studies with alvimopan suggest that it may normalise bowel function without blocking opioid analgesia in abdominal laparotomy patients with opioid-related postoperative ileus...
- Ghrelin improves burn-induced delayed gastrointestinal transit in ratsH S Sallam
Division of Gastroenterology, Department of Internal Medicine and Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA
Am J Physiol Regul Integr Comp Physiol 292:R253-7. 2007Delayed gastrointestinal transit is common in patients with severe burn. Ghrelin is a potent prokinetic peptide. We aimed at testing the effect of ghrelin on burn-induced delayed gastrointestinal transit in rats...
Research Grants81
- Food Rheology and Exercise in Aging HumansWAYNE CAMPBELL; Fiscal Year: 2005..e., insulin, leptin, cholecystokinin, glucagon-like peptide, apolipoprotein A-IV, ghrelin, glucose, and gastrointestinal transit time). Study 3 will assess the clinical implications of the chronic intake of liquid vs...
- Gastrointestinal Transit Measurement SystemDAVID KYNOR; Fiscal Year: 2006..In many patients, measurement of gastrointestinal transit can provide important diagnostic information...
- Optimization of HPMPA and CDV Analogs for Treatment of SmallpoxKarl Y Hostetler; Fiscal Year: 2010..to evaluate the effects of chemical structure on their metabolic stability in monkey liver S9 fractions, gastrointestinal transit and toxicity and test them in lethal animal models of poxvirus disease including, ectromelia, cowpox and ..
- mu Opioid Receptor Function in the Enteric Nervous SystemCatia Sternini; Fiscal Year: 2007..N-Methyl-D-Aspartate receptors (NMDA-Rs) are likely to be involved in the ¿OR-mediated impairment of gastrointestinal transit induced by prolonged ¿OR activation...
- Food Rheology and Exercise in Aging HumansWAYNE CAMPBELL; Fiscal Year: 2009..e., glucose, insulin, leptin, neuropeptide Y, cholecystokinin and gastrointestinal transit time)...
- GDNF in the Enteric Nervous SystemYun Xia; Fiscal Year: 2007..Human trials showed evidence of a prokinetic action on gastrointestinal transit. The general scientific aim of the proposed work is to understand how GDNF works in the "brain-in-the-gut"..
- BIOCHEMICAL CHARACTERIZATION OF OPIOID BINDING SITESGavril Pasternak; Fiscal Year: 1993..Furthermore, mu2 receptors mediate morphine's respiratory depression and inhibition of gastrointestinal transit. More recent work has suggested multiple kappa subtypes as well...
- Morphine Tolerance in Barrestin-2 KO Mice: Beyond PainLaura Bohn; Fiscal Year: 2006..questions: AIM I: To test whether morphine tolerance occurs in the suppression of respiration or gastrointestinal transit in mice that lack morphine antinociceptive tolerance...
- Triggering Mechanisms of Post-Operative IleusAnthony Bauer; Fiscal Year: 2007..Together these events succeed in delaying gastrointestinal transit, decrease local neuromuscular function, and activate neurogenic inhibitory pathways that suppress ..
- OPIATE RECEPTOR PHARMACOLOGYGavril Pasternak; Fiscal Year: 2007..Sigma1 receptors have been implicated in the modulation of opioid analgesia, but not gastrointestinal transit. Sigma1 receptor antagonists potentiate opioid analgesia and eliminate many of the differences in ..
- PHARMACOLOGY OF OPIOID RECEPTOR SUBTYPESGavril Pasternak; Fiscal Year: 1993..of opiate receptors in other opioid actions, particularly respiratory depression and inhibition of gastrointestinal transit. Finally, we hope to examine the interactions of nonopioid drugs upon opioid analgesia and other actions...
- Pharmacogenomics of Gastric Function & Weight in ObesityMichael Camilleri; Fiscal Year: 2007..It will also identify physiological and genetic factors that predict therapeutic success in the treatment of obesity with sibutramine. ..
- ALPHA-2 ADRENERGIC CONTROL OF COLONIC FUNCTION IN IBSMichael Camilleri; Fiscal Year: 2007..abstract_text> ..
- ALPHA 2 ADRENERGIC CONTROL OF COLONIC FUNCTION IN IBSMichael Camilleri; Fiscal Year: 2001....
- ALPHA 2 ADRENERGIC CONTROL IN IRRITABLE BOWEL SYNDROMEMichael Camilleri; Fiscal Year: 2007..Significance: This project will characterize pharmacogenetic mechanisms determining the response to clonidine through studies of candidate genes that control alpha2-adrenoreceptor function and norepinephrine transport in IBS. ..
- Pharmacogenomics of Gastric Function & Weight in ObesityMICHAEL L CAMILLERI; Fiscal Year: 2010....
- Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory FunctionsMichael Camilleri; Fiscal Year: 2009..to determine whether CB receptor modulation influences the antral motor response to a standard meal and gastrointestinal transit and to evaluate the interaction of muscarinic cholinergic mechanisms with CB modulation; second, to ..
- Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory FunctionsMICHAEL L CAMILLERI; Fiscal Year: 2010..to determine whether CB receptor modulation influences the antral motor response to a standard meal and gastrointestinal transit and to evaluate the interaction of muscarinic cholinergic mechanisms with CB modulation;second, to ..
- Pathophysiology of Anorectal DisordersAdil E Bharucha; Fiscal Year: 2010..This proposal will enhance our understanding of the mechanisms and assess novel approaches to manage FI. ..
- Novel Treatment Strategies for Constipation and Role of Brain-Gut axisSATISH SC RAO; Fiscal Year: 2010..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..
- Novel Treatment Strategies for Constipation and Role of Brain-Gut axisSatish Rao; Fiscal Year: 2009..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..
- Epidemiology and Mechanisms of Fecal IncontinenceAdil Bharucha; Fiscal Year: 2005..abstract_text> ..
- ANORECTAL MANIFESTATIONS OF FEMALE PELVIC FLOOR DISORDERAdil Bharucha; Fiscal Year: 2002..abstract_text> ..
- Novel Treatment Strategies for Constipation and Role of Brain-Gut axisSatish Rao; Fiscal Year: 2007..These studies aim to define the mechanisms of, and evaluate new therapies for dyssynergia, rectal hyposensitivity and rectal hypersensitivity, and could significantly impact constipation treatments. ..
- NEUROMUSCULAR CONDITION THERAPY-DYSSYNERGIC DEFECATIONSatish Rao; Fiscal Year: 2004..abstract_text> ..


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Nina Isabella
A friend once took a can of spray-paint to his front door and wrote in big letters "R U INSPIRED?" Since then, I've taken this on as my mantra. I quit my marketing job at Details magazine, studied interior design at Parsons, and worked for some pretty cool design firms in NYC, including Thom Filicia.
Now have my own interior designer + prop styling boutique whose goal is to create inspired, fresh & functional spaces. Ciao Bella! is a place where you can find my appreciation for all-things design, great shopping finds & the little things that make life more beautiful. My hope is to bring that inspiration to you so that you can find ways to use in your own lives.
Be inspired. x, Nina
I would love to hear from you! Shoot me an email: firstname.lastname@example.com
View my Design Work here: ninastyling.com
Or find me on:


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A 5K "Marthathon" will be held Nov. 27 to benefit USC freshman Martha Childress.
Childress, 18, was shot and paralyzed in a random shooting last month at Five Points.
Childress is spending the next few months recovering and learning new skills in Atlanta at the Shepherd Center for Spinal Injuries, her family said.
Proceeds generated from the race will go towards the Martha Childress Trust Fund and be used to pay medical expenses and help equip the family as they adjust to their new lives with Martha, her uncle Jim Carpenter said.
The race will start at 2 p.m. at the MESA Soccer Complex in Greenville. The cost is $15 for students and $25 for adults.
"I cannot wait to see everyone from all different colleges come back to Greenville for Thanksgiving and run together as one for Martha," said Bryce Conti, a friend and former classmate.
Martha tweeted Wednesday "One month ago my life changed forever. I'm so thankful I get another chance at life & thankful for those true friends who've supported me."
To register, go to www.go-greenevents.com or visit Martha's website at www.elephantstrong.org. A "Martha Strong" wristband will be included with each registration.
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Assisted Living
Accepting the need for assistance with daily living
Planning for assisted living expenses
While Medicare and supplemental health insurance may cover most of your medical services, assisted living and nursing homes may not be covered by insurance. The levels of care available and the costs can vary substantially. Research your options well before you need them and adjust your budget to account for these potential future costs. For help in learning about available services in your area, contact your state elder care ombudsman program.
Planning ahead can ease the transition into this phase of life.
As your need for physical care increases, your options may include:
- Home care — If you need a little help around the house, caregivers can be hired as necessary.
- Assisted living facilities — These are residential facilities that offer personal care services, such as meals, housekeeping, and entertainment, along with varying levels of assistance with daily activities, including bathing, dressing and medical needs.
- Nursing homes — These hospital-like facilities are for people who need the kind of round-the-clock care and supervision not available in assisted living communities.
Assisted living costs vary depending on geographic location, the size of the apartment within the community and the level of care provided, among other factors. As you and your financial professional plan for these costs, you may consider:
- Should I liquidate assets, such as selling my home?
- What are my income alternatives?
- Do I qualify for any government or veteran's benefits?
- Does my estate plan account for end-of-life expenses?
Plan with us
It's important to discuss these issues with your family and loved ones. Eldercare planning may be easier if major decisions are made before the needs arise. It may take some of the emotion out of the process and can make the transition easier on everyone. We can help you to make smart financial decisions as you plan for this normal life transition.


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By Carey Purcell
08 Jan 2014
Harris, a five-time Tony winner, died Aug. 24 at age 87. Her numerous stage credits include I Am a Camera, The Lark, Forty Carats, The Last of Mrs. Lincoln and The Belle of Amherst. She received a Lifetime Achievement Tony Award in 2002.
An objection to Harris' will has been filed by Herbert Nass, a lawyer who represented Harris for many years until he was dismissed toward the end of her life, claiming she "was not of sound mind or memory" when leaving part of her fortune to her caretaker, Francesca Rubino.
A soap opera actress who goes by the stage name Francesca James, Rubino was named co-executor of Harris' estate, which sources say could be worth as much as $10 million; Rubino could earl commissions of up to $200,000. She also inherited $50,000 outright.
Rubino took out a harassment prevention order that barred Gurian from entering Harris' house three years ago. Harris' longtime housekeeper Kathryn Bowden was fired and banned from entering the property, and her gardener was also fired.
The Post reports that Bowden was stopped by a policeman when driving to Harris' house and served with a letter from attorney Isaac Peres that read:
"It has recently come to Julie's attention that you have made several slanderous statements about another member of the team [Rubino]. These statements upset Julie a great deal... as a result, she no longer wishes to employ you. In addition you are no longer welcome on the property... any entry onto the property will be treated as a trespass."
Nass filed an objection to the will in December 2013 with the probate court in Barnstable, MA, stating the will and codicil "were procured by fraud and undue influence practiced upon the decedent" by Rubino and Peres.
A pre-trial hearing has been scheduled for Feb. 19 in Barnstable, MA.


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Places - Sangerville, "Life on the Farm in the Old Days"
Story: "Life on the Farm in the Old Days"
Storyteller: Sunny Stutzman
Town: Sangerville, ME
Collector: Pauleena MacDougall
Date: August 27, 2011
Sunny Stutzman's story relates some basic differences between life on the farm in the old days and now, but also generally differences between life on the farm and anywhere else in society. The story begins with a simple instruction to clear the fields of rocks, an odious task any farmer, or even gardener, in New England has at some point undertaken. But unlike most of our experiences, this story involves an aid we only dream about every Spring: dynamite. Without spoiling the story's finale, suffice to say that things go awry. It is not entirely clear when, where, or from whom Sunny learned the story, but the evidence places this before his time, with his father as the original storyteller. The presence of the Model T suggests the events occurred sometime in the early twentieth century. The somewhat cavalier use of dynamite also suggests that this story took place some time ago. Though not likely to be used in this manner now, at least not by unsupervised thirteen year old boys, dynamite was an important tool for farmers (as heard here), loggers (for clearing logjams), and other professions in "the old days." Stories that include dynamite are usually warnings or laments about the dangers involved, and where this story really stands out is its humorous take on what is otherwise a very dangerous activity. But, as Sunny says, "that's kinda how things go on the farm."
This story was recorded at the 2011 American Folk Festival. Sunny Stutzman was a member of the panel on the Narrative Stage called "Maine Farmer Poets." With him on the panel was poet Pat Ranzoni of Bucksport. Sunny's father and band-mate, Sid, was supposed to be a member of the panel but was unable to attend for health reasons. In addition to telling a few stories, Sunny performed several songs written by his father about life on the farm.P4899: Dynamite was used in the workplace not only for clearing fields of rocks. Here it is being used to break a log jam on the Saco River.
My father told me I have to tell one story of the way things were, I guess, on the farm. This is one I can tell in public. But it just gives you an idea of, maybe, the way farm life is different from everyday life, I guess. So, years ago there were two kids, about thirteen years old, on the farm. Their job was to take the rocks out of the field so that they could plant. So, of course all the rocks had to be removed with oxen at the time, this quite a while ago, and oxen can only move a rock that is so big. They gave these two kids who were only thirteen years old a box of dynamite and told them to go out and clear the field of rocks. And this was pretty much common practice in the neighborhood, apparently, back then. So, down the road, I'm imagining some kid a little bicycle with a box of TNT on the back, I don't know. They were probably riding both on one bicycle, who knows? Or maybe they brought the oxen down first. But, anyway, so they're in the field and they're blowing up rocks, having a great time I'm sure. I don't even know if they paid them really! One of these stray rocks goes through a window of a Model T Ford that was for sale on someone's lawn. The owner comes out all mad, "You kids bought that now. You're going to have to pay for that." These two kids looked at each other and the box of dynamite, and they said, "Well, we own it, what are we going to do with it?" They took the dynamite over, and they loaded the car up with dynamite, and they blew the car up right there on the guy's lawn. And apparently, I guess the guy didn't come back out; I don't know if they ever paid for it or not, but that's just, that's kinda how things go on the farm.


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The Southwood girls basketball team began their quest to defend their 2013 class 5A state title Thursday night. The Lady Cowboys hosted Carencro in their first postseason without their legendary, longstanding head coach Steve McDowell. The Lady Cowboys advance with a 69-54 win.
Green Oaks hosted Parkview Baptist and rolled on to win 49-35 to advance to the second round of the postseason.


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Metro police have identified the victim of a fatal crash on D.B. Todd Boulevard overnight.
The crash happened just before midnight on D.B. Todd near Hermosa Street.
Police said 92-year-old Ford E. Otey died at General Hospital.
Investigators said Otey's son, Ford R. Otey, crossed the center line and crashed into another car.
He was taken to Vanderbilt University Medical Center in critical condition.
The driver of the other car, Henry Jackson, was also taken to the hospital, but his injuries were not as serious.
Police do not know why Ford R. Otey crossed the center line.
They said there is no evidence of drug or alcohol involvement.
Copyright 2012 WSMV (Meredith Corporation). All rights reserved.


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A man is accused of taking pictures of women inside of a restroom at an Evansville pharmacy.
Evansville police said it happened around 3:30 p.m. Fridays afternoon at Walgreen's on St. Joseph Avenue.
Police said 20-year-old Brice A. Cannon filmed all four Walgreen's employees who were working at the time.
Employees told police that Cannon had been walking in and out of the women's restroom.
When police looked at Cannon's phone, they found at least six videos depicting women walking into a stall and using the restroom.
Police also said a younger female, approximately 12 or 13-years-old was in one of the videos as well.
Police believe Cannon held the phone under the stall's wall as he filmed each person. Cannon's phone was taken by police for forensic examination.
He is charged with voyeurism with a video camera and is held on a $500 bond.
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Testicle Torture Vids & Forced Ejaculations
This video is the latest in a series of testicle torture vids involving forced ejaculations. A forced ejaculation is where a mistress uses ball tying or other testicle torture techniques combined with forceful handjobs until the guy is forced to cum. The idea is that the more erect the cock becomes, the more painful the balls will become due to the swelling. When the sub is stimulated so much that he is forced to ejaculate, the ejaculation becomes painful as well as incredibly intense. This is something which should not be tried at home (unless you've done your homework and understand how to do it safely); you have been warned!
Testicle Torture Vid - Click Here
In this testicle torture and forced ejaculation vid the mistress is a sexy BBW with huge tits. She expertly ties the guy's cock and balls before beginning to stimulate him with a very expert handjob. She even uses her big tits on his cock to get him to swell up and to make the restrictions on his balls tighten. She then brings him close to orgasm several times before eventually forcing him to ejaculate.
The intensity of the pain and pleasure in this guy's ejaculation is evident in the loud cry that emits from somewhere deep inside him as begins to shoot his spunk. With the first muscular spasm there is an ear splitting groan and you can see his entire body jump up off the table. This is followed by a series of painful thrusts and muscle spasms as thin white liquid leaks from the end of the guy's cock and onto the mistress' hands.
To watch this testicle torture and forced ejaculation video right now, just follow this link...


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We're sorry but we couldn't find any ads matching your search for 'jack wolfskin' in County Antrim in Tents.
Please try one of the following options:
- Search in a broader location such as Northern Ireland or search across the entire United Kingdom.
- Search in a broader category such as Camping & Hiking or search across All categories.


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Adam Aleksander
Events designer, creator, and magician. Promoting underground and unusual culture events. (Anything Fun, Unusual, & Intriguing)
- Followers
- 18 followers
- Events
- 12 added
Member since Sep 5, 2012
- Home
- New York, New York
- Birthdate
- October 10, 2012
Kim Gardner
Super Project Manager at Flavorpill. Lover of the interwebs. Not-so-closet geek. Life-long learner/teacher. Beer aficionado/snob.
Mark Mangan
I'm cofounder of Flavorpill. Find something amazing here, and rally
Gabriela Filasky Arp
Project manager at Flavorpill who loves social activism, documentary photography, brains, small things and empanadas. In fact, secretly wish my nickname was empanada mama.
Jill Knight
Danielle Brock
shark lover. party starter. matching floral tops and shorts wearer.
Asha Saluja
Christopher St. Onge
Ashley Waghorne
Leah Taylor
Lover of NYC generally; immersive performance, specifically.
Ruta Karasik
Tasha Blank
beats / bass / riddims
Aparna Mukherjee
Living Jazz Archive
I live for jazz and beyond, in NYC and beyond.
Steven Chan
Monica Katz
Benjamin Ickies
Jordan Annis
Margot M
Likes playing music, activism, doodling and putting songs in the order God intended. 50% of Verbena Djs. www.verbenadjs.jimdo.com


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April 10, 2008
Lee County -- The former Chief Deputy Clerk for Lee County Superior Court claims she got fired simply because she decided to run for her boss's job.
Sara Clark says that's the only reason she can come up with. She says clerk Sondra Cook walked into her office with this box yesterday and handed her a separation notice without any explanation.
Sara said she was surprised by her firing. "She told me to turn over my keys, just unexpectedly gave me a box, dropped it down by my feet, and said I need you to turn over your keys, and empty out your desk and exit the premises, and I was shocked. I asked her why, I said Sondra you're kidding, and she said no I'm not."
Cook wouldn't talk to us today but issued a statement saying she fired Clark because she was taken off guard by her decision to run for the office.
Cook wrote "the fact that I had to learn of my position by reading it in the newspaper rather than my opponent discussing it with me indicated a lack of candor and reliability necessary in an office such as ours."
Feedback: email@example.com?subject=LeeCountyClerkFired/WJ
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Learn more about Hope's Wishbone Earrings- Gold Plated/ Pave CZs:
Manufacturer: WMU
Mfg Part#: 713775ddi
Sku: 226671786
See more in Jewelry & Watches
|"Gold plated wishbone earrings with pave set CZs are sure to become your new favorite jewelry! Stud backings hold the shining gold wishbones close to your ears. These earrings are a unique alternative to traditional clover and horseshoe lucky charm jewelry. Simple, sparkling chic design brings good luck all year round. Earrings are available in rhodium plated sterling silver or gold plated sterling silver. Don't forget to shop our collection of wishbone necklaces, wishbone rings, and wishbone earrings as well!This item is part of our nickel free jewelry collection!Weight: 0.05 g per earring Metal: Vermeil - 14k gold plated .925 sterling silver jewelry Stone: Cubic Zirconia Carat: Round cut CZ approx .005 carats (1.0 mm) Measurements: 0.5 in (12.7 mm) x 0.25 in (6.35 mm) FYI: This item is part of our nickel free collection!"


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President Obama signs the Tribal Law and Order Act into Law. Photo from Whitehouse.gov
Many people (including yours truly) have been lauding the recently passed Tribal Law and Order Act for the steps it takes towards solving the sexual assault crisis on Indian Land. An article posted today to the Social Sciences Resource Network by Suzianne D. Painter-Thorne begs us to take a second look. Painter-Thorne lucidly argues that the TLOA does not go far enough in changing the basic jurisdictional "knot" that has caused the law enforcement problems on Indian land. She writes that the crisis will continue because
Ultimately, the TLOA perpetuates a broken jurisdictional scheme by continuing to vest lawI brought news of the TLOA to you regarding the pandemic of sexual assault on Indian land. One in three Native women will be sexually assaulted in her life time, compared to one in four non-Natives. In 2007, NPR covered this story, an example of how the jurisdictional knot that Painter-Thorne's article addresses, results in a lack of justice for Native women. In the story, which Painter-Thorne's article opens with, the victim of a brutal rape is questioned by the FBI, gives a statement, identifies her assailants and witnesses, and then succumbs to her injuries. Her case is never investigated. No one even interviewed the named witnesses or interrogated the named assailants. Why? A jurisdictional clustermug.
enforcement responsibility in the hands of remote federal officials who
have proven unlikely to investigate criminal complaints, to arrest suspects,
or to prosecute offenders.
According to Painter-Thorne's article, entitled "Tangled Up in Knots: How Continued Federal Jurisdiction Over Sexual Predators on Indian Reservations Hobbles Effective Law Enforcement to the Detriment of Indian Women" the TLOA does not take any steps towards addressing this problem.
One of the more disturbing reasons she presents regarding federal officials' tendency to not follow through on investigations is:
Off the record, federal law-enforcement officials admit that U.S.Painter-Thorne goes on to criticize the provisions of the Act that supposedly create incentives for federal officials to investigate crimes on Indian land, and the liaison system set up by the bill as poor substitutes for locally based law enforcement and jurisdiction. She points out that evidence sharing is made even more convoluted by the Act. She concludes that this is not only an issue of sovereignty, as has often been argued, but that
attorneys view prosecution of reservation crime as a waste of prosecution
resources. Many simply find sexual assault cases insignificant compared
to their usual cases involving terrorism, organized crime, drug offenses,
and racketeering. According to former U.S. Attorney Margaret Chaira,
federal attorneys often balk at taking sexual assault cases, complaining that
they "did not sign up for this," but instead had planned to handle whitecollar
crime, conspiracy, and drug cases.
local control of law enforcement makes practical sense and isYou can read the full article here: "Tangled Up in Knots: How Continued Federal Jurisdiction Over Sexual Predators on Indian Reservations Hobbles Effective Law Enforcement to the Detriment of Indian Women"
more likely to repair the broken tribal law enforcement system by placing
responsibility for policing Indian communities in the hands of those most
accountable to their communities.
While it is clear that the Tribal Law and Order Act is a step in the right direction, it is only ONE step.


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Already assured a spot in the next round of Eurobasket, Italy played hard against the reigning Olympic $ilver medalists, Spain, and won their first game in the 2nd round of Eurobasket. Gigi didn't have a great game but chipped in 11 points, 4 boards and a block playing 22 minutes. He shot 44 % overall but only 20% from three. We will have to wait for the results of the Finland and Slovenia game before knowing officially who Italy will play next but based on the competition graph i think it will be Lithuania on the 18th
Right team wrong day the 19th!.


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Underrated: "He Had A Gift & Unfortunately The Car Accident Took It Away"
Tuesday, May 29, 2012 12:15AM
[Each week, SOHH asks two entertainment personalities to name who they feel is the most underrated emcee in hip-hop. After DJ Stimulus gave Beanie Sigel the title last week, radio veteran Russ Parr names D.O.C. SOHH Underrated.]
The most underrated artist to me has to be D.O.C. That's who I would have to name as my pick for SOHH Underrated.
I think he was clever. His writing was very clever. He was so nice and he had a gift and unfortunately the car accident took it away. It took away his gift. He ended up writing a lot of stuff for a lot of West Coast artists.
He did a lot of writing anonymously and with credits, but he got cut off pratically at his peak. I saw this guy and I knew it had to be frustrating. He wrote lyrics for Eazy-E and all of them cats and he was so unique. Dr. Dre saw that in him, he knew he was gifted.
I used to go out to the studio and on tours with those guys. I'd even put Everlast as an underrated cat. He was off the hook.
Currently, Parr is the host of the nationally syndicated Russ Parr Morning Show heard weekdays by more than 3.2 million listeners in 45 U.S. cities. He also hosts a weekend show, On Air with Russ Parr, which can be heard on more than 40 different radio stations. Aside from his radio gigs, Parr is also the co-host of the TV One dating show Get The Hook Up. He has also directed films including The Last Stand, Love for Sale, Something Like a Business, 35 & Ticking.
Check out D.O.C.'s music below:


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Deputies say a Spartanburg man is accused of raping a young girl who then tested positive for a sexually transmitted disease.
Joshua Bullis, 24, was charged with criminal sexual conduct first degree with a minor under age 11.
Deputies say medical tests showed the victim contracted Chlamydia during the assaults.
Deputies say Bullis attacked the child inside his home between May 19 and May 29.
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I stayed in the Hotel Beaune for one night - when I arrived there was no one there, but the owners had thoughtfully written me a letter that was attached to the front door (in English!). This gave me precise instructions as to how to get in through the security gate, how to find my room and where to park... More
- Official Description (provided by the hotel):
- Located in the heart of Burgundy, the historic town of Beaune is the ideal place to stay if you want to sample some of the many fine wines for which this area of France is internationally famous. The town itself offers plenty of interest, including the Burgundy Wine Museum and the 15th century Hôtel-Dieu charity hospital with its colourful tiled roof and acclaimed alterpiece of The Last Judgment by Rogier van der Weyden. Stars Beaune is situated close to the town centre and within easy reach of the A6 autoroute. Guests breaking their journey at this comfortable hotel will find 37 well-equipped rooms, each with satellite television. ... more less
- Reservation Options:
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- Also Known As:
- Beaune Stars Hotel