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The preseason seems meaningless for the Washington Redskins, since they don't have Robert Griffin III, but they're pleased with the way their defense has looked against NFL starters. The Buffalo Bills, on the other hand, have little to be pleased about after getting more or less wrecked by Washington.
Let's let Bills blog Buffalo Rumblings sum up the team's 30-7 loss:
Buffalo's defense gave up 452 yards. The offense didn't register a first down after halftime. Seven penalties and two turnovers were committed. Kevin Kolb and Stephon Gilmore got hurt. Week 1 is 15 days away.
Fun! Yes, Kolb is injured after suffering from concussion-like symptoms, E.J. Manuel is still hurt after undergoing a minor knee procedure that ended his preseason, and that means the Bills' quarterback depth chart right now just has one name on it, and that name is of undrafted rookie Jeff Tuel. Thus, the Bills are working out Matt Leinart and John Beck, but it's not a pretty situation whatsoever. At least they have two whole weeks to figure it out.
Meanwhile, the good feelings are flying in Washington, where the Skins are 3-0. As Redskins blog Hogs Haven notes, the strong defensive performance bodes well for the team's first real game:
One of the storylines coming into the game was to see how the Redskins defense would cope against the up-tempo, no-huddle offense that the Bills run. The Redskins open their season on Monday Night Football against Chip Kelly's Eagles, who run a constant up-tempo offense. When the Redskins managed to get off the field early, they used the tempo to their advantage, giving the Bills defense little time to rest. But on the Bills scoring drive, you could see the defense was tired.
In the red zone, the Bills were playing a numbers game. The Redskins wanted to cover the pass, leaving them with hat-for-hat on the inside. That's an obvious read for the Bills, who hand off up the middle and score. When the defensive front is tired after an up-tempo drive, they aren't going to get much push against the run. The Redskins needed to load the box and force the pass on the outside, trusting their corners to make the play.
The Redskins outgained the Bills 452-155. Next up for Buffalo is Detroit, while Washington heads to Tampa Bay to try and close out a perfect preseason.
More from SB Nation NFL:
• Play the No. 1 free fantasy football game
• VIDEO: Rex Ryan's press conference meltdown
• Geno Smith channels Dan Orlovsky in safety
• NFL preseason Week 3: Complete coverage
• Did the NFL strongarm ESPN out of concussion reporting?


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NAIROBI, Kenya Ś The websiteÆs headlines trumpet al-ShababÆs imminent demise and describe an American jihadist fretting over insurgent infighting. At first glance it appears to be a sleek, Horn of Africa news site. But the site Ś sabahionline.com Ś is run by the U.S. military.
The site, and another one like it that centers on northwest Africa, is part of a propaganda effort by the U.S. militaryÆs Africa Command aimed at countering extremists in two of AfricaÆs most dangerous regions Ś Somalia and the Maghreb.
Omar Faruk Osman, the secretary general of the National Union of Somali Journalists, said Sabahi is the first website heÆs seen devoted to countering the militantsÆ message.
ōWe have seen portal services by al-Shabab for hate and for propaganda, for spreading violence. We are used to seeing that. In contrast we have not seen such news sites before. So it is something completely unique,ö Osman said.
But although he had noticed prominent articles on the site, which is advertising heavily on other websites, he had not realized it was bankrolled by U.S. military.
The U.S. military and State Department, a partner on the project, say the goal of the sites is to counter propaganda from extremists ōby offering accurate, balanced and forward-looking coverage of developments in the region.ö
ōThe Internet is a big place, and we are one of many websites out there. Our site aims to provide a moderate voice in contrast to the numerous violent extremist websites,ö Africom, as the Stuttgart, Germany-based Africa Command is known, said in a written statement.
Al-Shabab and other militants have for years used websites to trade bomb-making skills, to show off gruesome attack videos and to recruit fighters. The U.S. funded websites Ś which are available in languages like Swahili, Arabic and Somali Ś rely on freelance writers in the region.
Recent headlines on sabahionline.com show a breadth of seemingly even-handed news. ōDeath toll in ambush on Kenyan police rises to 31,ö one headline said. ōUgandan commander visits troops in Somalia,ö another reads.
Web ads for the site appear on occasion on mainstream websites such as YouTube, and they show a clear anti-terror slant. Ads showing men on the ground blindfolded or SomaliaÆs best known American jihadi, Omar Hammami, entice web users to click. They then access a headline like: ōSomalis reject al-ZawahiriÆs call for violence,ö referring to the leader of al-Qaida.
The site, which launched in February, is slowly attracting readers. The military said that Sabahi averages about 4,000 unique visitors and up to 10,000 articles read per day. The site clearly says under the ōAboutö section that it is run by the U.S. military, but many readers may not go to that link.
Abdirashid Hashi, a Somalia analyst for the International Crisis Group, said he has read articles on Sabahi, mostly because of advertisements on other Somali websites, but he also didnÆt realize it was funded by the U.S. He said he has no issues with the U.S. government running a news site.
ōI donÆt think they hide it. ThatÆs up there. ThereÆs an information war going on, so I donÆt have any problem with that,ö Hashi said.
Osman said the articles on Sabahi are accurate and professional. But he said he feared that militants could attack writers who work for the site. Eighteen Somalis who work with media outlets have been killed this year, often in targeted killings.
Somali writers ōcan lose their life for working for this kind of a news outlet because of the extremists who target any critical voice or news service,ö Osman said. ōThe other issue is professionalism, because if someone is intimidated and is threatened all the time then he or she is reduced to self-censorship. He or she would be afraid if he files some important news that he would be targeted.ö
The military said there are nine writers who work for Sabahi from Kenya, Tanzania, Djibouti and Somalia. The other site Ś magharebia.com Ś concentrates on Libya, Algeria, Morocco and Mauritania.
Africom says the websites are part of a larger project that costs $3 million to pay for reporting, editing, translating, publishing, IT costs and overhead. It believes the project is paying dividends.
ōThe fact that we have seen an increase in website traffic is good news alone. The websiteÆs readers provide a significant number of comments on a regular basis, which often reflect their growing frustration and anger with extremist organizations in the region. Those comments are one indicator of a positive effect,ö Africom said.
Seth Jones, the associate director of the International Security and Defense Policy Center at the Rand Corporation think tank in Washington, said a significant part of the struggle with extremist groups like al-Shabab is ideological and is a battle for the hearts and minds of local populations.
ōBased on this reality, the U.S. and other governments should be involved in countering extremist messages on websites and other forms of social media. After all, every Arab government provides substantial money to television, radio, print media, and Internet sites,ö Jones said.
ōThey key question for the United States is gauging whether locals view these kinds of news sites as legitimate sources of information and read them. If not, itÆs worth asking: Is the United States getting a bang for its buck?ö
On the Internet:
Somalia news site: http://sabahionline.com/enŚGB
Maghreb news site: http://magharebia.com/cocoon/awi/xhtml1/enŚGB/homepage

subset: commoncrawl


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How much data do your kids need to use their mobile devices? In addition to KnowMyApp.org, which gives you an estimate on some of the most popular apps' data usage BEFORE you download them, there are also parental control tools available to help you estimate your kids (or your own) usage before choosing your data plans.
We've identified some of those apps or features on our Parental Control Tools section of GrowingWireless.com; look for the "Calculator" symbol ().
For more information on parental controls tools and resources for parents to monitor and manage their kids' wireless use, visit GrowingWireless.com.


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Today on "MMA Nation" we'll be joined by "the veteran voice of the Octagon" Bruce Buffer. We'll talk to Buffer about his new Internet radio show on Sherdog.com, his alleged fight with Frank Trigg in an elevator, UFC 100 and more.
We'll also talk the Bobby Lashley vs. Bob Sapp "Ultimate Chaos" event, the new UFC magazine, a recap of last weekend's TUF 9 Finale, this terribly tragic news and more.
"MMA Nation" airs every Saturday 7:00pm EST to 9:00pm EST on 106.7 WJFK. To listen live over the Internet, go to WJFK's website and click "Listen Live".
I'm also now on Twitter: @mmanation.
"MMA Nation" is also available by podcast on iTunes.
Number to call: 800-636-1067
Email here.
Talk to you then.
Ultimate Chaos: Lashley vs. Sapp coverage


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That's right…it's spring time. Spring is one of periods out of the year where your building's HVAC equipment can maximize utility savings through economizer use. Economizers are one of the most widely overlooked components related to HVAC in terms of operational status. Your company spends a bundle to have automatic economizers installed on their
Is Ice Cold Additive Safe for Heating and Cooling Systems?
For some time now there have been additives available for heating and cooling systems. Two such additives that claim huge savings and equipment longevity are Zerol Ice and Ice Cold. You can visit their links to view their statements regarding their products. This article need not be long as the answer for the topic


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Find and book great restaurantsFind a Restaurant
Editor's Pick
See more Editor's Picks
|1-5 West Street, London WC2H 9NQ
|020 7836 4751
|Price: £55.00
|Wine: £25.00
|Champagne: £63.00
|Opening Hours:
|Mon-Sun 12N-11.30pm (Sun -10.30pm)
This review hasn't been rated yet.
So there was about a seven year gap between my first visit and second visit and I am happy to report The Ivy is as good as it has ever been. Managed to get a Fri lunchtime slot for me and my guest with literally only three days notice. The dining room is as buzzy as ever and as some other diners have reported, the tables are a little too close together… The food however was excellent. Starters were duck salad and poached salmon with horse radish creme – both really good. We decided to go for the rib eye and all the trimmings. It's a steak and It's the staple of many restaurants however this was exceptional to say the least. Highly flavoursome and melt in the mouth medium rare perfection. Better than the Hawksmoor or Gaucho in my opinion. The deserts were Creme Brule – yes another omnipresent dish. However again, possibly the most delicious example of this desert I have ever tasted in any restaurant – that nearly took the score up to 10 out of 10! Not sure why this place has attracted so many complaints of being over-rated as we had a great meal, The service was also spot on, attentive and not over bearing. Well worth a trip I think although for me it's not the type of place I'd want to spend an entire evening in, probably best used as a lunch venue.


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What's a Fourth of July celebration without a sweet, big wedge of dripping watermelon? Taking this sweet flavor note, we thought why not grill the fruit to add some lovely smoky flavor? Grilling the watermelon takes two minutes. Once you...
Peach Sriracha Hot Wings
For a light zesty snack or a swingin' spicy meal, hot wings hold a special place in the heart of many Americans. From basketball to baseball to football to underwater basket weaving, competitive sports have long been a pretext for consuming finger-licking...Read more
Lomo Saltado Recipe + Chef Merito Giveaway
Don't you hate when you try a dish from a new cuisine and you always end up ordering the same one every time? That's me with Peruvian food. I was first introduced to Lomo Saltado, a classic Peruvian-style stir-fry of steak and...Read more
Avocado and Yellow Heirloom Tomato Gazpacho
In Extremadura they do it with bits of ham. In Cordoba they do it with hard-boiled eggs. In La Mancha they cook it with rabbit. In Cadiz, during times of drought, they make it creamy with less water. Gazpacho has many faces,...Read more
Blueberry Granita
With the sun beating down our house with its Southwestern exposure, it seemed there would not be any time to make dessert for dinner. But the ripe blueberries nesting in the refrigerator, graciously provided by the U.S. Highbush Blueberry Council, were...Read more
Don't Let Summer Pass Without Trying This Grilled Peach Salad with a Ginger-Lime Dressing
We have two weeks (longer if you're lucky enough to live in sunny California) to smell the roses, soak up the sun, jump into waves, and grill, grill, grill! With peaches at their peak seasonal ripeness, we have easy access to the...Read more
Strawberry Icebox Pie
Strawberry Icebox Pie Okay LatinoFoodie Nation, I love to bake, but I'll be honest with you: I'm still learning the science of baking. Make no mistake, the temperature of your kitchen, the moisture in...Read more


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Thursday, October 14, 2004
Drudge is reporting that the Democratic National Committee is issuing a 66-page manual to instruct workers on pre-emptive strikes declaring voter intimidation. Naturally, the DNC is denying the allegations.
One top DNC official confirmed the manual's authenticity, but claimed the notion of crying wolf on any voter intimidation is "absurd."If you want to see what they're talking about, click here for a picture of the instructions.
"We all know the Republicans are going to try to steal the election by scaring people and confusing people," the top DNC source explained.
Comments: Post a Comment


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Is your resume in need of a little disruption?
Startups are all about
making things work better.
Our resume writing service is all about doing that for your CV.
StartUpHire is the place to find jobs at Edison startups. Review the list below of Edison startup jobs. These Edison, NJ jobs at start-ups represent some of the most rewarding careers available. You can refine your job search for Edison jobs by adding a job title, company name, or keyword to the search box above … or click the "Advanced Search" link for more options. Don't see the employment opportunity you're looking for? Check back soon for more startup jobs in Edison, or sign up for an email alert (link in upper left) to receive periodic updates on new start up jobs in Edison, NJ.
About RiseSmart RiseSmart is a dynamic HR Technology Company that provides cutting edge career transition solutions to help employers with their workforce strategy, and displaced employees with their career strategy. We pride ourselves on helping our clients get into their next7/15/2014 New York, NY Save This Job
RiseSmart is looking for talented resume writers to join their team of professionals. RiseSmart is a dynamic, fast-paced Silicon Valley venture backed HR Technology Company that provides next-generation Outplacement solutions. We help employers with their workforce strategy and7/15/2014 New York, NY Save This Job
Description We are looking for exceptional software developers to help us take Fitocracy to the next level. Our team is solving really tough problems all set behind an awesome user experience that needs to scale to millions of users. You must kick ass at Python, Django, and7/15/2014 New York City, NY Save This Job
About RiseSmart RiseSmart is a dynamic fast paced Silicon Valley venture backed HR Technology Company. RiseSmart provides Next-Gen Outplacement solutions. The company leverages a semantic job search technology platform, proven methodologies, and one-on-one support to help7/15/2014 New York, NY Save This Job
Our first employee approached us and he made us pay attention by building cool, useful stuff that would clearly push Fitocracy forward. So go ahead and send us a resume, but don't expect to stop there. At Fitocracy, we focus on shipping so be prepared to show us your GitHub7/15/2014 New York City, NY Save This Job
Internal Projects - Corporate Application Support Reval is looking for a Corporate Application Developer who will join the Internal Projects team in New York City. The Internal Projects team is responsible for providing internal support to other Reval Departments in the7/14/2014 New York, NY Save This Job
Responsibilities The Director, Human Resources NA is responsible for the HRA department?s mission in the NA region to enhance7/14/2014 New York, NY Save This Job
About the Position: The Software Engineer will play a key role in the advancement of Reval?s Flagship application Reval as well as the development of new products. The candidate will be responsible for the design and implementation of new functionality and framework7/14/2014 New York, NY Save This Job
About the Position: Client Support is looking for a candidate who can help support their North American clients with an emphasis on providing valuation and hedge accounting technical expertise. The role will involve assisting on Reval Center client implementations, client7/14/2014 New York, NY Save This Job
Job Description: This position is responsible for helping drive category revenue and marketer adoption of Tremor products by working in conjunction with sales, marketing, PR and product teams. The position requires the ability to apply category and market expertise to decipher7/14/2014 New York, NY Save This Job
TheInfoPro, a division of 451 Research and the premier provider of peer-based research for Global 2000 Information Technology (IT) Professionals, is seeking a Data Research Analyst, responsible for data analysis and visualization, report production and chart creation, data7/14/2014 New York, NY Save This Job
451 Research, an independent IT analyst company focused on the business of enterprise IT innovation, is seeking an Account Executive. This position will involve prospecting and closing new clients as well as some retention of existing clients. The position could be based in San7/14/2014 New York, NY Save This Job
Position Responsibilities: Plans and prepares production schedules for manufacture of industrial or commercial products: Draws up master schedule to establish sequence and lead time of each operation to meet shipping dates according to sales forecasts or customer7/14/2014 Branchburg, NJ Save This Job
Position Summary The Community Manager serves as a member of our growing Client Services team based in our New York office. You will be the primary community manager for 2-3 Fortune 500 brands, and will be responsible for the growth, engagement, innovation and quality of their7/14/2014 New York, NY Save This Job
NIKSUN is the recognized worldwide leader in making the Unknown Known, by using next generation technology that revolutionizes the way networks and services are secured, protected and managed. The company develops and deploys a complete range of award-winning forensics,7/14/2014 Princeton, NJ Save This Job
The datacenter industry is expanding rapidly across the globe, and the technology and the supplier ecosystem is changing dramatically, as innovators disrupt the status quo and the cloud and a host of associated technologies drive demand. The 451 Research is looking for an7/14/2014 New York, NY Save This Job
451 Research, a leading technology analyst company, seeks a process-oriented editor to manage the daily flow of content for a rapidly growing mergers-and-acquisitions database, and an associated newsletter aimed at VCs, bankers and executives. Both products (the 451 Research M&A7/14/2014 New York, NY Save This Job
Responsibilities: ?Notifies and locates customers with delinquent accounts ?Attempts to secure payment, via using postal services, telephone, or e-mail ?Mails form letters to customers to encourage payment of delinquent accounts ?Confers with customers via telephone in attempt7/14/2014 New York, NY Save This Job
Tremor Video is looking for an experienced IT Engineer to join our IT Department. Our IT Department responsibilities include end to end responsibility for all Windows Server operating systems and related functions. The ideal candidate would be an IT Engineer with expertise in the7/14/2014 New York, NY Save This Job
About the Position The Account Management team in North America is being expanded and Account Directors (AD?s) are needed to support this expansion. The primary responsibility of this new role is the ownership and accountability of the North American client account base7/14/2014 New York, NY Save This Job


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10 Bizarre Tattoos
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Tattoos have always been a tradition method of self-expression. But sometimes that self-expression expresses just a little too much and many times you just have to wonder what people were thinking when they decided to get these tattoos.
To Do List Tattoo
Now this is an interesting tattoo but I think that eventually it may become a tattoo that they will regret. As someone who has a wrist tattoo having something that you are going to see almost constantly every day it really has to be something important and personal. But just maybe this tattoo will keep it's novelty and be cool to the person who has it. At least I really hope so.
Six Pack Tattoo
I suppose if you know that you're never going to get in shape then this might be a good idea seeing as it will be the closest thing you will ever get to a six pack. Though I think it also gives new meaning to the phrase "beer gut." Sometimes you got to think about the reason people get tattoos because like other tattoos this is only funny the first time you see it.
I See You Tattoo
This is another unique tattoo that really I cannot understand why someone would get it. Sure I mean you do it once and it is kinda funny and it will definitely catch you off guard. But after that it gets old rather quick, so I think that the goal of this tattoo is to constantly keep meeting new people. Once again I think I can respect it but I think in the long run this could be a rather silly tattoo.
Cow Tattoo
Now there are a number of tattoos that utilize holes in the body in order to add another dimension to their tattoo. Many of the more disturbing and unique ones, use holes that well I was not comfortable sharing pictures of. Turning the belly button into an anus has become a… shall I say "popular" bizarre tattoo as I have seen it done with a few different animals. This is possibly the best of the worst but many of them I have seen with cats.
Alien Tattoo
This is a truly impressive tattoo and this would really make anyone double take when you walked by. This is a bizarre but really cool tattoo and unlike some of the others on this list I really don't think there is too much to complain about. I would really like to hear the story behind this tattoo though and I would also like to see people's first reactions when they see him walking by.
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Search for Attorneys by Office Location and/or Client Services.
James M. Simpson heads the firm's General Litigation Practice Group. He has tried more than 135 jury trials to verdict in business litigation and personal injury matters including business torts, products liability, toxic torts and class actions for Fortune 1000 companies in a broad array of industries, representing clients in courts throughout the country. Jim successfully argued the constitutionality of Arkansas's electronic gaming law before the Arkansas Supreme Court.He regularly represents major product manufacturers and suppliers as regional lead counsel. His civil litigation defense experience extends to complex litigation involving termination, unfair competition and other trade practices, antitrust, cooperatives, and product distribution.
Jim is listed in The Best Lawyers in America and in Mid-South Super Lawyers as a Top 50 lawyer for Arkansas, and is honored to be a Fellow of the American College of Trial Lawyers. He previously served as President of the Arkansas Chapter of the American Board of Trial Advocates.
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The TeamWork :
Teamwork international provides life, opportunity and hope to suffering people around the world through disaster response and development programs. Teamwork International is dedicated to simplify human suffering. Teamwork international is non-political and non-sectarian in its mission.
This TeamWork agenda is:
- Education
- Health And Care
- Rehabilitation
- Developement
- Emergency Relief
Buy And Sell On Ebay For TeamWork
You can find whatever you're looking for on eBay – from baseball cards to new cars and more. When you do, shop for items that benefit us. You can get a great deal and support educating children & women at the same time! Shop now to support: Teamwork International compaigns. You can also support Teamwork when you sell on eBay.
Recent News
Japan's most powerful earthquake has struck the north-east coast, triggering a massive tsunami. Cars, ships and buildings were swept away by a wall of water after the 8.9-magnitude tremor, which struck about 400km north-east of Tokyo. A state of emergency has been declared at a nuclear power plant, where pressure has exceeded normal levels.
An earthquake of 7.4 magnitudes hit the country on Wednesday at 1:28am. The shocks of earthquake were also felt in India, Afghanistan and UAE. According to the US Geological Survey, the intensity of the quake was 7.3 and its epicenter was around 50 kilometres west of the town of Dalbandin, close to the border with Afghanistan.
A 7.0 earthquake struck the country of Haiti, leveling buildings, cutting off communications and leaving the world wondering about the state of this poor country. Witnesses said buildings were destroyed and many people injured. The lack of communications is hindering the ability to determine the full extent of damage and destruction.


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PHOENIX - After a shaky transfer of coaching power, the staggering Phoenix Suns, headed for Sacramento with Lindsey Hunter in charge on the bench and without two of the team's highest-profile assistant coaches.
It will be the debut of Hunter as interim coach, the first game he has coached of any kind. Hunter, brought in by general manager Lance Blanks a few months ago as player development director, replaced Alvin Gentry, who left last Friday in what the team described as a mutual parting of the ways.
Blanks chose Hunter over Suns assistants Dan Majerle and Elston Turner, among others. Neither Majerle nor Turner showed up for any of the practices since Hunter was hired. Majerle, a former Suns star player and one of the most popular sports figures in the Phoenix area, has let it be known he won't be back. Turner is a highly respected assistant who has interviewed for at least four NBA head coaching jobs, including the one in Phoenix when Mike D'Antoni left for the New York Knicks. Turner almost certainly has left his Suns job for good, too.
After practice Tuesday, Hunter said he wasn't sure of the status of Majerle and Turner, but he certainly spoke as if he knew they wouldn't be rejoining the team.
"I understand their situation," Hunter said. "As an aspiring coach, this is what you want to do in life, and it's disappointing when you don't get an opportunity. I definitely understand, and my heart goes out to both of those guys, and I wish them the best in whatever they do next."
Igor Kokoskov, a Suns assistant who also was interviewed for the interim job, will be Hunter's lead assistant.
"He's more of the opposite of me. He's an offensive guy," Hunter said. "We need those guys, unfortunately, in basketball. You need an offensive guy. I'm a defensive guy."
Other than that, Hunter wasn't sure which of the remaining personnel would be on the bench as assistant coaches in Sacramento.
"We're just trying to get some stability and find out what's what," Hunter said, "and all of those things will be hashed out."
The Suns are at the bottom of the Western Conference at 13-28, their worst record halfway through a season in a quarter century. They have lost 13 of 15 and are just two games ahead of Washington for the worst record in the NBA.
Now they face what Hunter called a "brutal" schedule."
Phoenix is home Thursday night against the Los Angeles Clippers, then is at San Antonio and Dallas this weekend.
Next week, they are home against the Lakers in Steve Nash's first trip back to Phoenix since leaving the team. Then there's a home game against Dallas, followed by a road trip with stops in Golden State, Memphis, New Orleans and Oklahoma City.
• What: Suns at Kings
• When: 8 p.m.
• TV; radio: FSAZ; 1490-AM


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What's on
in the mind of someone with years of experience on the keyboard and a computer
science degree from CalTech under his belt? Musical software, of course! We had
the opportunity to sit down with Michael Wilson, a graduate student at Stanford
University's Center for Computer Research in Music and Acoustics (CCRMA) and
learn about his creative process. Be sure to visit Michael's music page to hear what we're so excited about!
performance was part of a student concert called "Modulations," a showcase for
music produced by students of Stanford CCRMA. I played two pieces entitled
"Machine Triumphant" and "Efficiency." Both featured software that I wrote
myself and were performed by me on my keyboard, the Akai MPK61.
What kind
of software?
It's a
standalone piece of software written in C++ that seeks to encapsulate my
Masters education at CCRMA, especially one class on digital audio effects and
another on real-time audio systems development taught by my adviser Ge Wang. It
contains a compressor, delay lines, distortion—basic effects that you can find
in any digital audio workstation, but I wanted to gain an intimate
understanding of what they do on the computing end of the spectrum. None of the
sounds were really new, because that wasn't the goal for me.
music was relatively accessible in presentation and composition compared to the
other quite experimental music at the show. It evoked Dream Theater and prog
rock, and even vintage video games. What's your history in terms of composition?
I never
had any formal training in composition, but I began to take piano lessons when
I was three years old. My teacher, Keiko Kobayashi, remains a huge influence on
my music. She encouraged me
to write songs without imposing on my ideas or style, and entered me in this
competitive composition program called "I Can Compose, Too!" I remember arguing
with her over a specific chord in one piece; she let me make the final call,
but at the competition the judge said something like, "Why did you use this
chord?" But that was the way I wanted to do it. Besides the keyboard,
the computer has always been a great outlet for my creativity. The sounds and
music in the video games I played on my Nintendo NES as a child heavily
influenced my electronic composition. I started making sounds with an
electronic keyboard and a computer in grade school, and used MIDI as early as
the sixth grade.
What was
your first computer?
first keyboard composition?
I composed
a piece for piano called "Arrowhead," part of the composition
competition program that I participated in under the guidance of my teacher
Miss Keiko. I was four years old. My first electronic piece was called "The
Cat's Meow." I had a bunch of animal sounds in my MIDI library, and that one is
all cats.
A cat
study...interesting. It seems like learning is a trend in your songwriting
couldn't be more true of the compositions I did for Modulations. I could have
done everything higher-level than I did, but I wanted the challenge of making
the software myself. I wanted to have total control over the audio buffer and
also enable real-time playability. The only thing I didn't write is the
sequencer. I used Rosegarden, an open-source Linux MIDI sequencer, to cue all
of the other instruments during my live performance.
Where does one even begin with music software development in C++?
I used
the RtAudio and RtMidi libraries for C++. These handle the real-time audio
processing functionality. Plugins are great because it's easy to share your
stuff---they're compatible with any DAW so it's a great way to get exposure in
the music software engineering community. But when you write an audio plugin, it
necessarily restricts the way that you handle your data. A standalone gives you
complete access to it.
other gear is in your bag?
the Akai, I own a Yamaha YDP-223 which is a great digital piano to practice on.
I still have my first keyboard from college, the Yamaha PSR-500M. I also have
the Yamaha Motif Rack ES and the Akai LPK25, which I bring everywhere.
Any new
additions on the horizon?
If I could have one more
keyboard … that's a tough one. There are a lot of great products out there. My motivation
for getting the Akai 'board was that I wanted something without built-in
sounds, mostly to encourage me to develop my own system, but also for cost and
size considerations since I'd have to carry it around in my small car. It hit a
nice balance of controllers, size, and price for me. I'm a big Yamaha fan. If I
could have someone follow me around carrying dozens to hundreds of pounds of
gear, I'd like to have any of their top-end synths or digital pianos. I think
the ideal keyboard for me might have to be something I piece together
myself...we'll see if I ever get around to that.
These are my comments.
Robbie Basho Tribute Concert Benefits Documentary
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Original Jethro Tull Bassist Glenn Cornick Dies
Welcome to Bass Player's October 2014 Links Page
Maroon 5 Premieres New Track 'Animals'
123creative Presents 4 Preset Banks for Cakewalk Synths
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Fender Releases Limited American Standard Guitars, Plus New Classic Player and Special Edition Blacktop Models
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Q: What is the most common nutritional disorder in the world?
-iron deficiency is a common form of anemia and probably the most common nutritional disorder in the world
-most common in North American and European women of child bearing age as a result of bleeding
-6 – 8 x higher in countries where little meat is eaten
Q: What is the normal total body iron content?
-2+ grams in females, 2-6 grams in males
Q: What percent of the iron ingested is functional?
-80% of iron is functional, hemoglobin contains about 70% of body iron, iron also found in myoglobin, and iron containing enzymes (e.g., catalase and cytochromes), 15% - 20% is storage iron (hemosiderin, ferritin)
-1 gram of hemoglobin contains about 3.4 mg of iron
Q: What is the average intake and loss of iron daily?
-intake about 10-15 mg/day, about 10% of which is absorbed (mostly in duodenum, some in jejunum
-males/non-menstruating females lose approx. 1 mg/day, menstruating females lose about approx. 2 mg/day (40-60 mL during normal period)
Q: What happens with iron loss INC?
-if lose > 80 mL/period then you eventually develop iron deficiency
Q: What does transferrin do?
-is an iron binding protein (beta-globulin) that transports iron in plasma, responsible for delivering iron to immature erythroid cells
Q: What are hemosiderin granules?
-aggregate masses of iron stored in cells
-hemosiderosis- innocuous excess iron accumulation in organs, e.g., the liver and spleen
Q: What does ferritin do?
-a protein and iron complex (apoferritin is the protein portion) found in many tissues, is the major tissue protein for iron stores, minute amounts of ferritin are normally found in plasma
-serum levels are a good indicator of body iron stores (exceptions - not reliable in patients with liver disease, inflammatory states, (infections and non-infections) and malignancies)
Q: What are the levels of ferritin that lead to diagnosing iron deficiency or overload?
-iron deficiency - serum ferritin is < 12 g/liter
-iron overload - values of 5,000 g/liter are possible
-each microg/liter of ferritin in plasma indicates about 10 mg of stored iron
Q: What are the three pools of iron compartments in the body?
-metabolic, storage and transit pool
Q: Describe the metabolic pool of iron.
-include iron hemoglobin, myoglobin, electron transport chain, proteins, and enzymes, most metabolic iron regenerated through RBC turnover
Q: Describe the storage pool of iron.
-major stores are found in hepatocytes and macrophages, iron is found complexed to apoferritin (a 450 - kDa protein that binds up to 4,500 iron atoms)
-body stores vary from children, males and females
-children and adolescence need iron for growth and storage is virtually absent
-adult males have iron stores that INC slowly (elderly is borderline toxic)
-women have minimal stores during child-bearing years (post-menopausal INC to parallel those of men)
Q: Describe the transit pool of iron.
-includes transferrin
-transferrin has two iron-binding sites, is a 80 kDa protein, turns over iron approx. 10 times/day, and iron delivery is mediated by transferring receptor
Q: Describe the mechanism of iron uptake by a cell.
-there are transferrin receptors (TfR) on cell surface that is necessary for iron uptake, TfR binds plasma transferrin with preference for diferric transferrin
-the TfR-transferrin complex is internalized via endocytosis, endosome has lower pH which causes detachment of iron, iron escapes into cytosol and TfR-transferrin complex recycles to cell surface (apo-transferrin is released and another diferric transferrin binds)
Q: What does the uptake of iron by the cell depend on?
1) concentration and percent saturation of transferrin
2) number of TfR's on cell surface
Q: Describe the mechanism of ferritin and TfR production.
-is depedent on iron in cytosol
-involves specific mRNA sequences (Iron - Responsive Element = IRE) that binds to Iron Binding Protein (IBP) which has a greater affinity for IBP in absence of iron
-ferritin production: IBP binds to IRE of ferritin mRNA and inhibits translation, thus, when cellular iron concentration is low, more IBP binds and suppresses ferritin production
-TfR production: IBP binds to IRE of TfR mRNA which leads to stabilization of mRNA, thus, low cellular iron concentration leads to increased TfR production
Q: Describe the levels of serum iron.
-may be decreased in severe chronic disease states (e.g., malignancy, uremia, cirrhosis and chronic infection)
-usually higher in morning, subject to considerable diurnal variation
Q: What are the normal serum iron levels?
- in men: 120 microg/dl
-women: 100 microg/dl
-normal individuals have transferrin that is about one-third saturated with iron
Q: What is total iron binding capacity of serum?
-approximately 300-350 microg/dl (frequently decreased with chronic illnesses and infections, neoplasms and arthritis)
Q: What are some differential diagnoses for hypochromic anemias?
1. Iron deficiency (DEC serum iron, DEC serum ferritin, and INC TIBC)
2. Anemia of Chronic disease (DEC serum iron, normal serum ferritin, DEC TIBC)
3. Thalassemia (normal serum iron, normal serum ferritin, normal TIBC)
Q: Why is iron low during an infection or chronic disease?
-when have a infection or chronic disease, want iron low because infection needs iron to survive, want low free iron and don't want iron to be transported (DEC serum iron and TIBC)
Q: What are some causes of iron deficiency?
-low dietary intake (common in infants, greatest need in first year of life, premature baby deprived of 3-4 mg/day, INC incidence in infants consuming only cow's milk)
-poor absorption (after gastrectomy or in patient with malabsorption disease, prolonged achlorhydria, surgery, etc.)
-excessive demand (pregnancy)
-chronic blood loss (the most common cause of iron deficiency in the western world, e.g., peptic ulcer disease, carcinoma, hemorrhoids, menses, hemosiderinuria, hemoglobinuria, etc.)
Q: What are the characteristics of hypochromia in iron deficiency anemia?
-significant hypochromia does not ordinarily develop until the bone marrow iron stores are depleted, early-on the anemia may be normochromic and normocytic, pass through a dimorphic phase of two RBC populations
Q: What happens to leukocytes during iron-deficiency anemia?
-WBCs and platelts in peripheral blood are not affected
-thrombocytosis often occurs
-retic count may be normal but usually DEC
Q: Describe the morphology of the bone marrow in a patient with iron-deficiency anemia?
-scanty, frayed, cytoplasm in later stage normoblasts w/ absent iron stores in bone marrow (Prussian Blue stain)
Q: With low levels of iron in iron-deficiency anemia, what can a depletion in iron containing enzymes cause?
-alopecia, koilonychias (spoon-shaped nails that are thin and ragged), atrophic glossitis, atrophy of gastric mucosa, malabsorption problems and pica
Q: What happens to the blood indices in iron-deficient anemic patients?
-MCV, MCH and MCHC may all be decreased by the time anemia appears, but not always
-MCV (45-67% of patients), MCH (80% of patients) and MCHC (20-80% of patients)
Q: From a nutritional standpoint discuss the relevance of iron in anemia.
-most diets in western world have adequate amounts. Exception = infants have increased requirements, especially from 3-4 months of age.
-considerable iron can come from cooking in iron pots
Q: What is hemochromatosis?
-iron overload syndrome with associated parenchymal cell damage (Prussian blue stain)
Q: What foods are high and low in iron?
-high in muscle, liver, soybeans, low in eggs, leafy vegetables, fish
Q: What may cause Pearl-iron deficiency anemia?
-Pearl - Iron deficiency anemia of unknown etiology in adult males or postmenopausal women (in the western world) should be considered to be caused by GI blood loss until proven otherwise!
Q: What are the sequence of events that leads to the development of iron-deficiency anemia?
1. iron depletion stage (iron is mobilized from stores, storage iron DEC, plasma ferritin DEC and plasma IBC (transferrin) INC
2. iron deficient erythropoiesis (when iron stores are depleted, plasma iron levels fall, saturation of transferrin falls below 15%, free red cell protoporphyrin INC and % of sideroblasts DEC in bone marrow)
3. iron deficiency anemia stage (anemia becomes detectable, gradually becomes microcytic, finally both microcytic and hypochromic)
4. anemia does not develop until bone marrow Fe stores are depleted (wehre they become microcytic and hypochromic-last thing we see)
Q: What is the treatment plan for iron deficiency?
-oral or parenteral (size of tablets is a compromise between what is needed and tolerated (about 1 in 10 get significant gastric or intestinal irritation))
-satisfactory response to oral medication - increase of 2 grams of hemoglobin after a 3 week trial
-6 months of oral medication are usually required to correct the anemia and replenish the iron stores
Q: In iron-deficient anemia, how are the RBCs classified?
-microcytic, hypochromic
Q: What are the components of the iron panel?
-serum iron, TIBC, serum ferratin and transferrin saturation
Q: How will the iron panel appear in patients with iron-deficiency anemia?
-DEC serum iron, INC TIBC, DEC serum ferratin, DEC transferrin saturation
Q: Why is TIBC INC in anemia?
-TIBC is a true measure of serum transferrin, which is elevated in these patients because liver makes more of transferrin to try to pick up more iron
Q: What does serum ferritin measure?
-is a measure of iron stores in the tissues because there is a certain percentage of iron that leaks out of these patients each day, proportional to amount of iron in tissues. Pick this test if can only pick one. Serum ferritin is affected by infections, inflammation, and neoplastic disease, so can lead to inaccuracies, these will lead to elevated serum ferratin levels.
Q: Why is serum ferittin level normal in some patients with anemia?
-If someone with anemia is not showing the microcytic, hypochromic, their serum ferratin may be elevated enough that it is up to the normal range (due to fever), but they are still anemic, so be careful.
Q: In what form of Fe is iron absorbed?
-iron is absorbed in the ferrous (2+) state
Q: What is atrophic gastris?
-pt produces no acid due to destruction of parietal cells, become iron deficient, because iron can't be made in the reduced state so there is no iron absorption
Q: What is the differential diagnosis for microcytic, hypochromic anemia?
-think of 2 diseases, iron deficiency or thalassemia
Q: How can iron deficiency and thalassamia be differentiated from each other?
-These can be differentiated through an iron panel (which is for iron deficient people) and see serum ferritin test, RDW is also elevated in iron deficiency but normal in thalassemia (problem in Hb synthesis)
-Patients that have thalassemias have other ways to diagnose (say through Hb electrophoresis)
-In Iron deficiency, most patients will come in with normachromic normacytic pattern, only when they are depleted of iron, will they show hypochromic and microcytic pattern.
Q: What stain is used to measure iron?
-Prussian blue, all blue deposits is where iron is
Q: What are some characteristics associated with iron overload?
-hemachromatosis, hemosiderosis, see lots of blue
Q: What are some characteristics associated with iron deficiency?
-there are no blue residues, microcytic and hypochromic
Q: When analyzing anemia, what are the steps involved in classifying the anemia?
-First must look at red cell morphology, hct and Hb, then can classify what type of anemia patient has based on the morphology of the red cells
-Then look at MCV and MCHC: size of red cell and amount of Hb in them
-RDW will give anisocytosis or not
-Finally look at platelets (normal is 150,000 – 400,000), Iron deficiency pts usually have thrombocytosis (increase in platelets). This is an indicator of iron deficiency because patients with thalassemia do not have thrombocytosis.
Q: What should be done if someone is suspected of being iron deficient but cannot afford iron panel?
-look at conjunctiva mucous membrane (sclera of eye), most people look pale, give a blous of iron and check on her in a week, to see if she's made progress, do H&H, retic count (to see if bone marrow is responding)
Q: What is the pathophysiology of megaloblastic anemia?
-anemia of ineffective erythropoiesis with impaired DNA synthesis, have bone marrow erythroid hyperplasia and a DEC retic count
-red cells are macrocytic, increased N/C ratio, prone to intramedullary hemolysis (elevated indirect bilirubin (ineffective erythropoiesis) and elevated LDH)
Q: What are the main causes of megaloblastic anemia?
-B12 deficiency or folic acid deficiency
-both are coenzymes in the pathway for DNA synthesis, deficiencies of either result in deranged or inadequate DNA synthesis, synthesis of RNA is unaffected therefore, cytoplasm develops normally
Q: Describe the morphology of peripheral blood in megaloblastic anemia.
-peripheral blood RBCs are normochromic, have marked anisocytosis and poikilocytosis (with MCV > 1003), and many macro-ovalocytes
-decreased reticulocyte count
-with severe disease nucleated RBCs appear
-neutrophils are large (macropolys), some are hypersegmented, often mild neutropenia
-thrombocytopenia common
Q: Describe the bone marrow morphology in megaloblastic anemia.
-usually hypercellular
-megaloblastic changes include (1) nuclear-cytoplasmic asynchronism or dissociation, (2) nucleus remains large and relatively immature, and (3) cytoplasm matures at normal rate
-granulocytes have (1) nuclear asynchrony, (2) "giant" metamyelocytes and band forms, and (3) hypersegmented PMNs
-megakaryocytes may be large or multi-lobulated
-M/E ratio is flattened or even reversed
Q: What are some causes of vitamin B12 deficiency?
-decreased intake due to (1) poor diet (rare) or (2) impaired absorption due to (intrinsic factor deficiency, pernicious anemia, total gastrectomy, malabsorption states (tropical and nontropical sprue), diffuse intestinal disease (regional ileitis), malignancies, e.g. lymphomas, fish tapeworm (Diphyllabothrium latum), chronic pancreatic disease, bacterial overgrowth
-increased demand due to (1) disseminated CA or (2) pregnancy
Q: What are some causes of folic acid deficiency?
-inadequate intake due to (1) inadequate diet – alcoholism, (2) impaired absorption – malabsorption, or (3) overcooking vegetables
-increased requirement due to (1) pregnancy, (2) infancy, or (3) markedly increased hematopoiesis
-impaired utilization due to folic acid antagonists (e.g. methotrexate)
Q: What diseases occur when a patient is unresponsibe to B12 or folic acid?
-unexplained disorders-pyridoxine-responsive megaloblastic anemia
-neoplastic (erythema myelosis)
Q: Describe some general information concerning pernicious anemia.
-due to chronic atrophic gastritis with failure of intrinsic factor production
-juvenile PA, not well understood, similar to adult form but onset in 20's
Q: Describe vitamin B12?
-contains cobalt atom and a corrin ring (similar to porphyrin ring), cannot be synthesized in human body
Q: What are the diet and requirements for vitamin B12?
-normal diets contain large amounts, only 2-3 ug required per day, total body pool is ordinarily 2-5 mg and several years are required to deplete normal reserves
Q: What is transcobalamin II?
-it is a plasma transport protein that delivers vitamin B12 to liver and other cells of body
Q: What two reactions in man are known to need vitamin B12?
-cofactor in conversion of homocysteine to methionine
-formation of succinyl coenzyme A
Q: Describe intrinsic factor (IF) and what it does?
-secreted by parietal cells in fundus of stomach (along with HCl)
-combines with ingested B12 to form a stable complex (which resists peptic digestion)
-mechanism of absorption (in ileum) is still unknown
Q: Describe the epidemiology of pernicious anemia.
-more common in Scandinavian, English and Irish descent (up to 0.2% of this population), slightly more common in males, more common after age 50
Q: Describe the pathophysiology of congenital pernicious anemia.
-is autosomal recessive
-total absence of intrinsic factor (IF) and normal secretion of other gastric juices, there are no antibodies to IF or parietal cells
Q: Describe the pathophysiology of the immunologic (autoimmune) form of pernicious anemia.
-there antibodies to parietal cells and IF
-cell mediated immunity is activated and include (1) lymphocytotoxic antibodies in one-third of patients, (2) CD4/CD8 ratio increased, and/or (3) Ts cells decreased
-chronic atrophic gastritis
Q: What is the clinical manifestation of pernicious anemia?
-insidious onset
-anemia and related symptoms including weakness, fatigue, and lightheadedness, severe anemia can lead to congestive heart failure
-type of hemolytic anemia (ineffective erythropoiesis) can lead to jaundice
-complaints of loss of appetite are common
-glossitis (50%)
-neurologic manifestations (subacute combined degeneration of spinal cord)
Q: Describe the neurologicals manifestations associated with pernicious anemia.
-degeneration involving the posterior and lateral columns of the spinal cord
Q: What are the laboratory findings associated with pernicious anemia?
-CBC-anemia with elevated MCV and macrocytes and hypersegmented PMN's
-serum Vitamin B12 levels
-10-50% of patients exhibit iron deficiency anemia
-bone marrow
Q: What Abs are synthesized in gastric mucosa in patients with pernicious anemia?
-Blocking antibody - blocks B12-IF binding (75% of patients)
-Binding antibody – interferes with B12-IF complex binding to ileal receptor (50% of patient
-Parietal canalicular antibody - less specific - found in 85-90%, but also in 50% of patients with atrophic gastritis not associated with pernicious anemia
Q: What is the Schilling Test?
-measures amount of radioactive B12 in a 24 hour urine (definite test)
(1) orally - give a small dose of radioactive B12
(2) two hours later, inject a large "flushing" dose of nonradioactive B12
(3) normal individuals will excrete 7% or more of the radioactive dose in the urine in 24 hours (patients lacking intrinsic factor do not absorb the B12 well and excrete < 7%)
-it is necessary to REPEAT the test giving intrinsic factor (porcine) orally along with the small dose of radioactive B12, if the patient has PA (and, therefore, lacks intrinsic factor) the result will be normal on the repeat test)
-if results are still abnormal, some other cause for the malabsorption must be sought, e.g., sprue, etc
Q: What does the validity of the test results show?
-validity of test result depends on good renal function and proper collection
Q: What is the treatment for PA?
-parenteral vitamin B12 q 1-3 months
Q: What is the function of folic acid?
-acts as an intermediary in transfer of one-carbon atom unit (formyl or methyl groups)
-needed for DNA synthesis
-plentiful in raw foods (eggs, milk, leafy vegetables), destroyed by cooking
-common type of deficiency
Q: What are the major causes of deficiency?
-decreased intake due to inadequate diet (alcoholics, indigents and elderly), is the most common cause
-decreased absorption (sprue, intestinal lymphoma)
-increased requirement (pregnancy, infancy, metastatic carcinoma)
-impaired utilization - particularly from antimetabolites used in cancer chemotherapy <methotrexate is a folate antagonist>
-alcohol also blocks the delivery of liver folate stores to the bone marrow
Q: What is the clinical manifestations of folic acid deficiency?
-same as Vitamin B12 deficiency but lacks neurologic changes, although dementia and depression have been reported, there are neural tube defects in fetus as well
Q: What are the laboratory findings for folic acid deficiency?
-CBC shows anemia with high MCV and macrocytes and hypersegmented PMN's
-folate levels, use red cell to meausre (more stable
Q: What role does pernicious anemia have on vita B12 deficiency?
-PA can cause vita B12 deficiency, is autoimmune disease in which antibodies are formed against parietal cells so cannot make intrinsic factor (IF). IF comes from parietal cells of stomach along with HCl
Q: Describe immunofluroescent assay.
-can show the Ab bound to the parietal cell. Use an Ab bound to a fluorescent dye as a marker against human IgG
-Direct test: take a cell (biopsy material) and add the flor labeled anti-human IgG antibody. Wherever human cells have an antibody, the anti-IgG will bind and fluoresce -> one step -> looking for cells already coated with ab
-Indirect test: ANA (anti-nuclear-antibody), have a target cell, add patient's serum to this and allow it to bind and then add the flor labeled antibody -> looking for ab in patient's serum
Q: Describe achlorhydria.
-not making HCl, person becomes iron deficient, this occurs in pernicious anemia because parietal cells are targeted
-This gives a MCV in normal range and RDW elevated -> have big and small cells, see macro, micro, and normacytic cells
Q: What are some other causes of vita B12 deficiency?
-rarely due to diet, GI diseases like Crohn's disease (ileitis), diseases of small intestine and ileum, tapeworms, bacterial overgrowth (Whipple disease), pancreatic insufficiency, terminal ileum resection
Q: What role does pancreatic insufficiency have on vita B12 deficiency?
-Normally, when ingest food, salivary glands produce an R protein that binds to B12 to make it resistant to the acid in the stomach -> goes to the small intestine -> pancreatic enzymes break off the R protein so B12 can bind to intrinsic factor and get absorbed. Thus pancreatic insufficiency leads to nonabsorption of B12.
Q: What does B12 deficiency lead to?
-Big cells due to asynchronous growth, delay of DNA synthesis in nucleus of red cells and cytoplasm has RNA and ribosomes, growing at a normal rate. Nuclear growth slows down, cytoplasm is maturing faster, thus asynchrony -> results in cells getting bigger, waiting for nucleus to mature
Q: In B12 deficiency, what does the bone marrow aspiration show?
-In bone marrow aspiration, cell is in prorubriocyte stage, cytoplasm large and dark because making Hb, leads to asynchrous development
Q: What are the cell characteristics in B12 deficiency?
-Cells have pink cytoplasm, but a non-condensed nucleus -> so get macrocytosis
-Both RBC and WBC are large, ANY nucleated cell is larger than it should be
Q: Which is more common, folate or B12 deficiency and why?
-folate more common than B12 deficiency because the body stores for Vit B12 are such that it takes a year for you to become deficient, whereas stores for folate are less so can become deficient in a couple of months
-the most common macrocytic anemia is megaloblastic anemia due to folate deficiency
Q: Why are the cells in the bloodstream of patients with megaloblastic anemia macrocytic?
-Macrocytes in the blood stream due to asynchronous development of blood cells, nucleus grows slower than cytoplasm due to deficiency in Vit B12 and folate defect in DNA synthesis. Second symptom is homocyst levels increase.
Q: Why is homocysteinuria bad?
-have increase in homeocys which is a risk factor for venous thrombosis and cardiovascular disease in large quantities
Q: What is on the differential diagnosis with a patient who has macrocytic anemia?
-B12 deficiency
-Folate deficiency, pernicious anemia
-Liver disease: patients produce a lot of cholesterol that binds to RBCs making them bigger in appearance
-Reactive reticulocytosis (so many reticulocytes, shift cells), these can all show an increase in the MCV, appearing macrocytic, CBC comments will say presence of polychromatophilic cells (multiple colors)
Q: What should patients with macrocytic anemia be tested for?
-serum B12-Can be equivocal, so give patient B12 (viscous injection) and follow up in 7-10 days, then perform H&H or retic count (but only if there was a previous baseline). If H&H goes up, probably had B12 deficiency, but can't be completely sure, will have to run a Schilling test to make sure and see where the problem actually was (IF, pancreatic, etc).
-serum folate- Since it is the most common cause, run this one first (Serum folate levels change more than RBC folate level, i.e. eating salad before test, so not correlated with the blood, best to do both RBC and serum folate levels)
Q: What is methyl-THF and methyl-THF trap?
-5-methyl-THF is made from serine and glycine by removing a methyl group, there can be a m-THF trap in which m-THF accumulates. Dimethyl THF leads to falsely elevated folate in the serum.
Q: What can cause methyl-THF trap?
-In reaction of homocysteine -> methionine, 5-methyl THF donates a methyl group, B12 is required. Without B12, get an accumulation of homocyteine AND methyl-THF trap! (Also involved in succinyl CoA)
Q: How does methylTHF trap show up in laboratory tests?
-Low red cell folate and elevated serum folate indicates methylTHF trap
Q: What is the difference between folate deficiency anemia and B12 deficiency anemia?
-Only difference between this and B12/pernicious anemia is that if it becomes severe enough, B12 can lead to neurological problems, resulting in demyelination of the posterior/lateral columns, get tingling/numbness of the extremities, psych problems, etc.
-make sure diagnosis for folate def. is really folate def. and not B12, because can lead to neurological damage
Q: If someone is diagnosed with B12 deficiency, and three months later they come back and look at the smear and they have macrocytes again, showing macrocytic anemia. Why does this occur?
-This occurs because when turn the red cells on, they go at max and use all the folate, so pt must supplement the folate from diet, or they may become deficient again, this occurs in someone who was treated for B12 deficiency. (RBC lifespan is 120 days.)
Q: What type of colon cancer is most responsible for blood loss?
-left sided colon cancer, napkin ring lesion, get stenosis of that lesion, right side is more hemorrhaging and blood loss, that is the tendency
Q: In what conditions is bone marrow non-functioning?
-myelofibrosis, myelometaplasia
-in this situations, you get INC CO, INC respiratory rate, INC erythroipoietin
-leads to extramedullary hematopoeisis (spleen and liver) and eventually splenomegaly and hepatomealy
Q: Why would end-stage renal function lead to anemia?
-DEC erythropoietin production
Q: Why are child-bearing age women susceptible to iron deficiency anemia?
-if they have prolonged menstrual cycles, can become iron deficient if lose enough blood (the population is most iron deficienct-women in there 20s or 30s)
Q: Why do long-distant runners have iron deficiency problems?
-have a tendency to hemorrhage because of length of exercise and distance of exercise (due to pounding of trauma)
Q: In patients with iron deficiency, what is the order of things seen during examination?
-DEC in serum iron, then DEC serum ferritin and then change morphology (hypochromic, microcytic)
Q: What are the components fo the iron panel?
-serum iron, serum ferritin, TIBC and % saturation
-serum ferritin is the best test (if only order one, then this is the one to order), levels of serum ferritin mimic the amount of iron being stored
-if serum ferritin is normal, then iron stores are normal, then not iron deficient, can therefore be anemia of chronic disease, iron is sequestered by macrophages and does not get into mature RBCs, there serum ferritin tends to be in the normal range, have DEC amounts of transferrin
Q: Describe hemachromatosis.
-will get into more detail
-condition inherited or acquired, absorb more iron (maybe 10-20X) than normal, body doesn't get rid of iron very well, body hangs onto iron very easily
-macrophages take up iron and store it
-over a long period of time the amount of iron that is around will surpass the engulfing capacity of the macrophage and is now stored in parenchymal cells, can't package it so try to start to metabolize it making free radicals killing the cells
-over time, if sufficient cells are dead that portion of the organ dies (liver, pancrease, heart)
Q: Describe the absorption of iron and its maintenance in reduced form.
-in GI tract as ferrous 2+ form, in order to keep Fe in the 2+ state, need an acidic environment (like stomach and HCl from parietal cells)
-in pernicious anemia, there is no HCl (destruction of parietal cells) so there is an iron deficiency (as well as a B12 deficiency)
Q: What is the differential for patients with microcytic, hypochromic anemia?
-iron deficiency, thalasseia, lead poisoning, anemia of chronic disease, sideroblastic anemia
Q: How is the iron difficiency differentiated from the differential for microcytic, hypochromic anemia
-thromobocytosis in patients who have iron deficiency
-also have pica (appetite for food without nutritional value, dirt)
Q: What conditions can cause an elevation in serum ferritin?
-inflammation, infection and malignancies, considered by soma positive acute phase protein
Q: What is a positive acute phase protein?
-an example would be C-reactive protein (CRP)
-a non-specific indiator of inflammation and infection (are elevated in instances of inflammation and infection)
-CRP hangs around until the cause of the response is accurately treated
-serrum ferritin is also considered an acute phase protein so may go up with inflammation and infection (don't waste your time running a serum ferritin with someone who has pneumonia)
Q: Why does chronic pancreatitis cause B12 deficiency?
-can't release R factor because don't secrete pancreatic enzymes
Q: Why does B12 deficiency lead to macrocytic cells?
-B12 is needed for the synthesis of thymidine, have problems with DNA synthesis but not protein, so nucleus is smaller than cytoplasm
Q: How does B12 deficiency lead to neurological problems?
-need B12 for methyl-malonyl -> succinyl CoA, end result is abnormal lipid metabolism and formation and demyelination of spinal tract (particularly the lateral tracts)
Q: what happens with LDH in hemolytic anemia?
-elevated LDH 1 and depression in 2 (1, 2 LDH flip), never run LDH on hemolyze serum because get 1,2 LDH flip
Q: Describe haptoglobin.
-protein that binds to free Hb, free Hb is toxic to cells in the kidney, produced by the liver, haptoglobin-Hb complex is taken back to liver
-individuals with hemolytic anemia have a DEC in haptoglobin, but INC in haptoglobin-Hb test
Q: What is the iron distribution in the normal body?
-approximately 80% of the functional iron is founding hemoglobin, myoglbin and iron-containing enzymes such as catalase and the cytochromes contain the rest
-the storage pool represented by hemosiderin and ferritin contains approx. 15% to 20% of the total body iron
Q: Where in the body is ferritn located?
-ferritin is found in all tissues but particularly in liver, spleen, bone marrow and skeletal muscles
-in the liver most ferritin is stored within the parenchymal cells, in other tissues it is mainly in the mononuclear phagocytic cells
Q: Describe the binding capacity of transferrin.
-synthesized in the liver
-about 33% saturated with iron, yielding serum iron levels that average 120 ug/dL and 100 ug/dL in women, so TIBC is 300-350 ug/dL
Q: How does chronic blood loss lead to iron deficiency anemia?
-most common cause of iron deficiency in the Western world, if bleeding occurs into tissues or cavities of the body, the heme iron can be totally recovered and recycled
-external hemorrhage as from GI tract (due to peptic ulcers, hemorrhagic gastritis, gastric carcinoma, colonic carcinoma, hemorrhoids), urinary tract (renal, pelvic or bladder turmors) or genital tract (menorrhagia, uterine cancer) deplete iron reserves
Q: Describe anemia of chronic disease.
-impaired red cell production associated with chronic diseases, most common cause of anemia among hospitalized patients in the US
-assocaited with reduced erythroid proliferation and impaired iron utilization so mimics iron deficiency
Q: What are the common features characterzing anemia of chronic disease?
-low serum iron and reduced total iron-binding capacity in association with abundant stored iron in the mononuclear phagocytic cells
Q: Describe the pathophysiology of anemia of chronic disease.
-erythropoietin levels are low due to generation of IL-1, TNF and interferon-gamma, these are made by the underlying chronic inflammatory or neoplastic disease
-these cytokines also release hepcidin which inhibits the release of iron from the storage pool
Q: Why is vitamin B12 and folic acid important for the body?
-they are coenzymes required for synthesis of thymidine, a deficiency results in defective nuclear maturation due to deranged or inadequate DNA synthesis with an attendant delay or block in cell division
-does not affect RNA and protein synthesis so cytoplasmic maturation proceeds in advance of nuclear maturation (nuclear/cytoplasmic asynchrony)
Q: Describe the steps involved in the absorption of vitamin B12.
-free B12 in the stomach binds to R-binders, in the duodenum, R-B12 complexes are broken down by the action of pancreatic proteases and release B12 with can then associate with intrinsic factor (which was made in the stomach by parietal cells
-IF-B12 is transported to the ileum where it is endocytosed, B12 then binds to transcobalamin II (carrier protein) that delivers B12 to liver and other cells
Q: What lab criteria are needed for diagnosing iron deficiency erythropoiesis?
1. DEC serum iron
2. normal to INC TIBC
3. DEC serum ferritin
4. DEC transferrin saturation
5. INC free RBC protoporphyrin


text: Machinedrum's acclaimed "Room(s)" will get an extended version on 21st April (yes, Record Store Day), with an extra CD, "Room(s) Extended", featuring more Travis Stewart goodness. The new reissue, on Planet Mu, includes three previously unreleased tracks from the recording sessions of the same LP, three B-sides from the "Sacred Frequency EP", and "TMPL", a bonus track from the iTunes version of the album. Furthermore, it also features five remixes from different album tracks by FaltyDL, Chrissy Murderbot, Lando Kal and Traxman. Check the full tracklist to the right.


text:
Blackhawk Chapter has approximately 40 members covering
meetings are held each year, two in the fall and two in the spring with an
informal get-together at convention. Meeting
dates vary in order to accommodate the largest number of members. Meetings
usually consist of lunch and an educational program. As most meetings are held in member homes with occasional meetings held
at a location having special interest and available luncheon facilities, members
most often provide the programs with talks regarding various aspects of
collecting and identification. Annual
dues are $10 per member.
There is a
wide range of interests and collections within the group. Both the novice and the advanced collector find that they are continually
learning through the chapter. It is
a great way to talk to people and see first hand about a specific type of
cutting, company, or designs that other individual members have detailed
knowledge of.
The ACGA has
over a dozen national committees that work on Catalogs, Marketing, Ethics &
Authenticity, Endowment Fund, and Long Range Planning just to name a few. The local chapter is a great way to stay abreast of all the details of
what is going on at the national level.
Blackhawk chapter hosted the ACGA national convention in 1993, an exhibit at the
Come to a
meeting and give us a try.
Verle Davison, President


text:
It's been more than 40 years since they defended freedom in Vietnam, but veterans of the Vietnam War were honored for their service during a ceremony at Veterans Memorial Park in Lake Charles on Saturday.
The keynote speaker of the Vietnam Veterans Honor Day was Calcasieu District Attorney John DeRosier, a Vietnam veteran himself. Reflecting on their sacrifice, DeRosier told them it's what defines America.
"Because not only are we willing to do it for ourselves, we venture and expend our lives to protect freedoms around the world. And very few other countries do that," said DeRosier.
The day was also about remembering the prisoners of war and those brothers and sisters still missing in action.
Lake Charles Mayor Randy Roach declared Saturday Vietnam Veterans Honor Day.
"For teaching us that young Americans must never again be sent to fight and die unless we are prepared to let them win," said Roach.
The recognition, even though some 40 years later, means a lot to these Vietnam vets. While most small towns welcomed their soldiers back from Vietnam, Vietnam veteran Bill Abshire recalls how soldiers were met with protests in the larger cities.
"We were treated like dogs, like baby killers. Little did they know we didn't start that war. We answered the call of our country and we did it to preserve the freedoms and liberties that all of our children, grandchildren and great grandchildren are enjoying today. And if that call came and I was capable, I would do it again," said Abshire.
"This day means a lot to me because when we came back in the early part from Vietnam, we didn't get a welcome - we got a disgrace to some of us. This here really makes you feel at home today," said Roy Sanders, Vietnam veteran.
Others have mixed feelings, but said it does them good to see today's men and women in uniform welcomed home.
"I personally think the recognition is a little too late. But what makes me feel good is the fact that we are recognizing the ones that are coming home now. And that makes me even prouder of what I did is that I can see these guys coming home and they are treated with a lot of respect - which they all should be. No one knows what they go through over there," said Bill Rister, Vietnam veteran.
Meanwhile, a memorial honoring First Lt. Douglas Fournet will be dedicated on the Fourth of July at Veterans Memorial Park. Fournet, a native of Kinder, died while serving in Vietnam. He was posthumously awarded a Medal of Honor for bravery in combat.
Copyright 2013 KPLC. All rights reserved.
320 Division Street
P.O. Box 1490
Lake Charles, LA 70601/70602
Phone: 337-439-9071
Fax: 337-437-7600
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Closed Captioning


text:
A judge denied Timothy Shannon bail this afternoon after Ocean County prosecutors charged him with murdering his wife.
Shannon, who police say is Hart City Council member, was arrested for the December 29th death of his wife Lee-Ann Shannon.
He originally called police to say Lee-Ann drowned accidentally in the bathtub at their home. Through their investigation, Oceana County Sheriff Deputies and Hart police determined that story did not add up.
Lt. Craig Mast of the Oceana County Sheriff's Office says Timothy's timeline of his wife's death was too inconsistent. In the week and a half since her death, medical reports and interviews lead them to arrest him.
Neighbors describe the couple as normal, and often saw them playing with their two children in the yard. The two children, ages 3 and 4, are now in the care of their grandparents.
Lee-Ann is described as enthusiastic volunteer with Hart's Head Start program. Both children attended Head Start and Lee-Ann was very involved in their education and finding opportunities to help the program as a whole.
"She wanted to be there for her kids," says Jodi Munoz, the director of Hart Public School's Early Childhood Programs. "She believed in paying it forward."
9&10's Michael Kasiborski and photojournalist Jacob Johnson have more details on Timothy Shannon's arrest.


text:
A1 motorway (Serbia)
|Autoput A1
|Route information
|600 km (400 mi)
|Major junctions
|Horgoš, Hungarian border
Belgrade bypass near Batajnica
|Preševo, Macedonian border
|Vojvodina, Belgrade, Šumadija, Preševo Valley
|Major cities:
|Subotica, Novi Sad, Belgrade, Smederevo, Jagodina, Kruševac, Niš, Leskovac, Vranje
|Highway system
|Highways in Serbia
Motorway A1 in Serbia spans approximately 600 kilometers (370 mi). It crosses the country from north to south, starting at Horgoš border crossing with Hungary and ending with Preševo border crossing with Republic of Macedonia. As a part of the Pan-European corridor X (along with route E70) and connection among Serbian biggest cities it is one of vital highways for Serbian infrastructure, and significant works are undergoing for its reconstruction and enhancement.[1]
The highway consists of three major sections: Horgoš–Subotica–Novi Sad–Belgrade (178 km), Belgrade–Niš (237 km) and Niš–Leskovac–Preševo–Macedonian border (152 km). After enhancement works, mostly completed in 2011, the whole Horgoš–Leskovac route is a complete dual carriageway. Enhancement of southern part, financed by Serbian Government and Hellenic Plan is still in progress. Northern and central section are linked through the heart of the city of Belgrade, but completion of the Belgrade bypass will provide a separate transit route.[2]
- ^ "Koridor 10: Gde naći 1,6 milijardi evra" (in Serbian). B92. 28 September 2006.
- ^ "Autoputem od Horgoša do Preševa oko 2011." (in Serbian). Glas javnosti. 7 December 2006.
A1 near Inđija
|This Serbia location article is a stub. You can help Wikipedia by expanding it.
|This European road or road transport-related article is a stub. You can help Wikipedia by expanding it.
|This article about transport in Serbia is a stub. You can help Wikipedia by expanding it.


text:
Colorado Rockies preview
Healthy Rockies lineup provides plenty of fantasy potential
Published: Feb 15, 2013
» Get updates via Sportsmail
This is the latest preview in a series examining the 2013 fantasy baseball outlook of each major league team. Today, a look at the Rockies.
The Colorado Rockies didn't generate many noteworthy headlines this offseason.
Get expert advice along with all the tools, analysis and projections you need to win your Fantasy League!
Fantasy Source is fully customizable. Personalize the content delivered to your home page, customize each page to fit your league's scoring system, and choose which stats get displayed.
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text:
Summer Reading Fun for Kindergarteners
July 30, 2012
Cleveland Heights, OH
Camp Jumpstart is a summer language program for kindergarten students that will help bring children up to the first grade reading level. Teachers work on classroom activities, such as Letter ID and Sounds, Letter and Word Work, Phonemic Awareness, Guided Reading, and a Writing Workshop. This takes place for four weeks in the summer, and ends August 3. Students are recommended to this program by their kindergarten classroom teachers from each elementary school.
Pictured here is Mrs. Lustic's P.E. class, where students are not only doing physical activities, but they must match the letters that they run around and collect to the master letter board. Then they recite the alphabet to make sure they have matched all the letters correctly. Combining this physical movement with the academic activity helps students to retain the information.
Fifty-one students are enjoying Camp Jumpstart, and once school begins, they will have enhanced their skills and be ready to read in first grade.


text:
The University of Iowa wrestling team won seven of 10 bouts to defeat Nebraska, 22-9, on Saturday at the Devaney Center. The win was Iowa's seventh straight in the series.
Thomas Gilman, Tony Ramos, and Josh Dziewa spotted Iowa a 10-0 lead with two wins and a major decision, but Nebraska kept things close with three wins in matches that featured ranked opponents.
It was a stretch that got UI head coach Tom Brands' attention.
"Those three matches - 149, 157, 174 - the whole country, or anyone paying attention to this dual meet, is talking about it, and we went 0-for-3," said Brands. "We won seven matches. I do not feel like we won seven matches. We left two major decisions off the board, but you have to keep moving forward."
Gilman used a point for riding time to defeat No. 9 Tim Lambert, 2-1, at 125. Ramos scored five takedowns to record his team-best fifth major decision, 15-4, at 133, and Dziewa used two takedowns and two near-fall points to win 9-2 at 141.
Nebraska (8-1, 2-1) closed to within 10-6 before intermission with a pair of wins at 149 and 157. Fifth-ranked Jake Sueflohn defeated No. 13 Brody Grothus, 5-2, at 149, and third-ranked James Green ended Derek St. John's 27-match win streak with a 9-7 win at 157.
Nick Moore used three takedowns to win 8-2 at 165, but fourth-ranked Robert Kokesh closed the gap with a 7-3 win over No. 6 Mike Evans at 174.
After Nebraska pulled to within 13-9, freshman Sammy Brooks swung the momentum back toward the Hawkeyes when he finished a single-leg with 17 seconds into the sudden-victory period to defeat No. 11 T.J. Dudley, 6-4, at 184.
"We knew if I kept the pressure on him his level would go down, so I just tried to keep my pace as high as I could, even if I wasn't feeling good," said Brooks. "You just push through and wrestle hard."
Brooks wasn't able to finish a number of shots in the first and second periods, but eventually caught Dudley on the edge and grabbed a 4-3 lead with 37 seconds left in the third. Dudley escaped to force overtime, but Brooks went right back to the leg, ending the match and earning his second straight win over a rated opponent.
"He is an athlete," said Brooks. "He can explode out and (avoid) the takedown, so you have to get ready. Ideally you don't even let that happen. You pick him up and put him down hard and get the takedown, but in a match like this it's going to take more than one attempt."
Brooks' win extended Iowa's lead to 16-9, and Nathan Burak (197) and Bobby Telford (285) closed with a pair of decisions for the final 22-9 score.
Third-ranked Iowa (11-1, 4-0) returns to the mat Saturday, Jan. 25 when No. 2 Minnesota visits Carver-Hawkeye Arena. Tickets are available through the UI Athletic Ticket Office over the phone at 1-800-IA-HAWKS or online at hawkeyesports.com. The dual will be televised on BTN.
"We have to get ready again. We have one dual this week and one dual meet the next week, and we have to put a lineup out there that is going to score," added Brands. "We have to use the whole clock. The whole seven minutes."
Notes: Attendance was 3,946... Iowa won its seventh straight in the series... Thomas Gilman improved to 5-1 against ranked opponents... Ramos earned his fifth major decision of the season... St. John's winning streak was stopped at 27, a career long... Sammy Brooks won his third in a row and second straight against ranked opponents.
#3 IOWA 22, #8 Nebraska 9
125 - #3 Thomas Gilman (IA) dec. #9 Tim Lambert (UN), 2-1; 3-0
133 - #3 Tony Ramos (IA) major dec. Shawn Nagel (UN), 15-4; 7-0
141 - #13 Josh Dziewa (IA) dec. Colton McCrystal (UN), 9-2; 10-0
149 - #5 Jake Sueflohn (UN)dec. #13 Brody Grothus (IA), 5-2; 10-3
157 - #3 James Green (UN) dec. #1 Derek St. John (IA), 9-7; 10-6
165 - #4 Nick Moore (IA) dec. Austin Wilson (UN), 8-2; 13-6
174 - #4 Robert Kokesh (UN) dec. #6 Mike Evans (IA), 7-3; 13-9
184 - Sammy Brooks (IA) dec. #11 T.J. Dudley (UN), 6-4; 16-9
197 - #16 Nathan Burak (IA) dec. Caleb Kolb (UN), 3-1; 19-9
285 - #3 Bobby Telford (IA) dec. Collin Jensen (UN), 2-0; 22-9
Courtesy: Iowa Media Relations
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Follow Bellator 114 results for the Shlemenko vs. Ward fight card Friday night.
MMA Fighting has UFC Fight Night 38 results for the Shogun vs. Henderson 2 fight card March 23 from the Ginasio Nelio Dias in Natal, Brazil.
Follow Bellator 113 results for the Vegh vs. Newton fight card Friday night.
Benson Henderson meets Rustam Khabilov in the main event as the UFC makes its debut in one of the sport's true hotbed cities.
Follow UFC 171 results for the Hendricks vs. Lawler fight card at the American Airlines Center in Dallas on Saturday night.
Follow Bellator 112 results for the Straus vs. Curran fight card at the Horseshoe Casino in Hammond, Ind.
Follow One FC 14 results for the Larson vs. Suzuki fight card at the Stadium Negara in Kuala Lumpur, Malaysia.
MMA Fighting has the Glory 14 results for the Cro Cop vs. Bonjaksy fight card Saturday at the Arena zagreb in Zagreb, Croatia.
Follow UFC Fight Night 37 results: Gustafsson vs. Manuwa for Saturday's UFC event from the O2 Arena in London, England.
Follow RFA 13 results for the Cochrane vs. Escudero fight card Friday night from the Pershing Center in Lincoln, Neb.
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text:
Photo Gallery
Around the Park
Mount Rainier National Park
Around the Park
Edith Creek as seen on a foggy, autumn day.Download 1.6 MB
Credit: NPS/Sue RussellPark visitors aren't the only ones who enjoy the meadows at Paradise.
Silver Falls trail, located near Ohanapecosh, showcases old-growth forest communities.
St. Andrews Lake, located on the western edge of the park, as seen from the Wonderland Trail.
The meadows of Sunset Park are abundant with wildflowers in mid-summer and are host to black bears foraging on the plentiful supply of huckleberries early in the fall.
You may encounter this bridge if you hike the southwest section of the Wonderland Trail.
Lowland forests, like this one at Longmire, are are dominated by western hemlock, Douglas fir, and western red cedar.
Snow Lake may have been named because the cirque in which it lies is filled by icy meltwater from the snowfields of the Tatoosh Range or because snow often rings the lake until late summer. Snow Lake trailhead is located near Paradise.
Changing with the season, there's always something to see on the trail to Snow Lake. In mid-summer, this area explodes with a variety of wildflowers and an abundance of beargrass. In the fall, mountain ash and huckleberries color the scene.
A waterfall seen along the Tahoma Creek Trail.
Most everyone is familiar with this very beautiful and common plant of the moist woods. …As the common and generic names simply the leaves and petals are in threes. The petals at first are pure white but turn a dark rose color with age. From the March – June 1938 edition of Mount Rainier National Park Nature Notes
One of the most common and beautiful plants of the deeply-wooded [lowland forest]. It is a perennial and grows to a height of 4-6 inches. In the late summer the plant is characterized by bunches of bright red berries which are very attractive and conspicuous. Thus, a second common name - Bunchberry has been given this plant. From the March – June 1938 edition of Mount Rainier National Park Nature Notes


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When Lee asked Janet for a backrub, she ended up massaging his sphincter with her tongue! Payton came by to return Rick's mitt, but ended up staying for lunch, she's going to toss the salad and eat his big Kosher Sausage! Vannah goes wild when she see's a plumber's crack hanging out, she can't resist tongue-fucking that working class ass! When John forgot Magdalene's Greek Caesar Salad she ate his Russian Ass Salad instead! Julie is a thick red-head who can't get wet unless you let her make out with your a-hole before you fuck her throat! Hot Pussy Fucking, Cock Sucking & Ass Rimming in every scene!


text:
What's in your trash? If you are not careful you could be
throwing away your identity and privacy.
WTOC has been exploring the topic in our Special Assignment:
Public Privacy and the mistakes we make by handing over valuable information to
Bank account statements and blank checks. Those are two of
the big ones but there is so much more we toss in the trash which not only
screams 'Identity thief, come and get it' but other types of trash which
basically tells them 'Come into my house!'
Shredding important documents is something we should do.
People WTOC quizzed claimed that's exactly what they do.
"You shred the paper," Kevia Shanteloo said.
"I got a shredder and I shred most of my stuff,"
Clint Leibel told WTOC.
"Before, I used to rip it up. Now, I shred
everything," Wanda McDonald said.
"Sometimes, I don't think about it and toss something
in the garbage can," Ron Palefsky told WTOC.
Palefsky should know better. "If I'm not careful, I
could be a victim too."
Palefsky is a private investigator with the Aaron Frederick
Agency in Savannah. When he's digging for information for clients, he sees the
mistakes we make with our trash daily.
"There are just so many things we throw away in the
trash. It can be an old insurance form. It could be an old bank statement. They
just don't think there is any valuable information to get off of it,"
Palefsky said. "Prescription drug bags. They have names, date of birth and
doctor. Sometimes you get social security numbers off that information."
You know all those credit card offers we don't want? A thief
would gladly dig into your trash to open it for you. In the wrong hands, it
could do some real damage. Same goes for those pesky receipts in your pocket.
"There is a lot of info on receipts we don't bother to
look at. You just crumble up and throw away," Palefsky said. "Sitting
outside a bank and watching people throw things away; I could come up with
identities, on any given day, of half a dozen people."
Save them and shred those receipts. Our private eye and
computer expert, Digital Doc of Savannah's Brian Hodge, both say Christmas time
for us is also Christmas for thieves who may go dumpster diving or peek at what
you got for Christmas online.
"You wouldn't leave the huge boxes for a new TV or
computer in your front yard and when you plaster Facebook with all the new
stuff you bought and say you are leaving town, you are asking for somebody up
to no good to check that out," Hodge said.
"They think no one is going to go through my trash. A
lot of times you'll see the shipping labels are still on the boxes. A lot of
information can come from that. You can tell a person's lifestyle, how many
people live there, if they have children," Palefsky said. "If it
works for us private eyes, it works for the everyday crook who knows people
throw away very valuable information."
Here's a rule of thumb. If in doubt, shred it. There are a
few things you should always shred.
-old tax returns
-bank statements
-credit card offers
-canceled checks
-convenience checks
If any of those items fall into the wrong hands, someone can
open an account in your name.
Tomorrow night, our Public Privacy series checks into those
health apps you get for your phone and just how easy they can be hacked.
Copyright 2013 WTOC. All rights reserved.
PO Box 8086
Savannah, GA 31412
FCC Public File
EEO Public File
Closed Captioning


text:
I know I do. I hate him because he's an idiot. God and I have a hatred of idiots in common(remember The Good, The Bad and The Ugly?) He's supposed to be a play by play guy but he never knows what is going on. He anticipates calls and usually get's them wrong. I remember one time seeing an official signal a technical foul just as they were going to commercial. When they came back the opposing player lines up to shoot the technical foul. Marlowe had no idea why that guy was shooting a free throw and mumbles something about a technical foul. We never and I mean never found out who the technical was on or what it was for. One time the official makes a big signal about the foul being before the shot. A player goes to the throw in spot indicated by the official, a bunch of player substitutions start and Marlowe says "We don't know if this is a shooting foul or not". He had to be the only guy in the building that didn't know if it was a shooting foul or not. It's embarassing to have to hear him make a fool out of himslef so much. So many times he says what is going on with the vocal inflection of a question as if he is asking Hastings or some behind the scenes guy what is going on. I spend half the broadcast correcting the TV about the stuff Marlowe got wrong.
I brought this up because some discussion was going on about the "local blithering idiots" vs. the national guys in another post. The national guys will at least stop their little chat about everything but the game in front of them to let you know what a call was or what was going on.
I do like Hastings because even if he is a homer, in the past he has not held back on criticising the players for bad decisions. I like it that he once in a while has those teaching moments where he's telling the young player's at home what to learn from what they are seeing. Don't forget that Hastings was in the NBA for a long time and he didn't make it on his good looks. He made it because he learned from coaches and did what he was told and played the role he was assigned. I remember when the Miami Heat had their first year. They had gotten in their first few players and Hastings was one of them. He was quoted as saying "Right now I'm the best player we have. If that doesn't change we're in a lot more trouble than anyone can imagine." He is not an idiot, but he plays one on TV, just to be one of the good old boys. I'd love to have him over to watch a game with me. Marlowe can stay home. In his case he really is an idiot.