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Community "Cooperative Polygraphy" Review: Lies, Lies, Lies YEAH!
Community S05E03: "Cooperative Polygraphy"
All praise the Laser Lotus! "Cooperative Polygraphy" was one heck of a great episode of Community, and the best of the show's revitalized fifth season to date. End of story. Well, not the end of this story, but at least the and of any lingering doubt that Community is back to form. "Repilot" showed us that Greendale could open its doors again, "Introduction to Teaching" showed us how the show could be infused with new life, and "Basic Intergluteal Numismatics" (a.k.a. "Intro to Butt Banking") showed us that Community still knows how to handle a stunt episode. But "Cooperative Polygraphy"? This was Community at its finest, no matter what part of the show's timeline you're talking about, a shoestring-budget masterpiece that maximized a simple premise to highlight the series' biggest strength: the bonds between the study group that've transformed them into a surrogate family. Oh, and I laughed. A lot!
Pierce wouldn't let a stupid thing like death get in the way of his penchant for instigating mayhem within the group, and in order to have a crack at his inheritance, the study group had to submit to being put through a lie-detector test to determine whether they were involved in Pierce's death (Pierce actually died by his own hands, literally). This idea—like the premise of the episode's spiritual predecessor, the super-brilliant Season 2 episode "Cooperative Calligraphy" (hey those titles rhyme!)—was so basic that it allowed the characters to dictate the story, and because Community's characters are so strong, they're fascinating even when they spend an entire episode bottled up in a room. And can't we all just admit that we love Community the most when the group is screaming at each other and then making up?
That inevitable moment of tenderness came from a surprising person: the ghost of Pierce Hawthorne. Despite his prickly legacy hovering like a wraith over the gang—couldn't you just imagine Pierce leaning back with his arms crossed, a smug smile plastered on his face, as the study group imploded on their own?—he posthumously showed off his softer side while dispensing his death gifts. He acknowledged Britta's passion even if she couldn't. He recognized Shirley's strength of character. He lauded Annie as his favorite. He didn't care much for Jeff and Abed, which was so fitting for his character and a testament to the writers not sending him off cheaply.
But dammit he loved his former roommate Troy. "Cooperative Polygraphy" had to take care of Community's most difficult storyline to date. Namely, sending Troy Barnes off on his path toward exiting the show. NOOOOOOOOO! (Donald Glover is leaving Community after the next episode, and yes you are allowed to cry.) But bravo for how the character's departure is being handled. It feels so right and respectful for Troy's character to go find himself, because he's always been the character who goes with the flow rather than blazes his own trail. And so now Troy's going to sail the Childish
Gambino Tycoon around the world and become a man. The sad inevitability heading into Season 5 was that Troy had to go; the silver lining is that he's going out in a way that really works. And do you realize that this isn't just Community recognizing a proud moment for Troy, but also for Mr. Glover, the actor? Giving Troy this send-off (and naming the boat after a nod to Glover's rapping alter ego) shows so much regard from the writers for Glover's personal decision to set out on his own that I might die. So touching. And so excellent. I'm going to miss the hell out of Troy, but this episode convinced me that leaving Community is the right decision for Donald Glover the human being.
"Cooperative Polygraphy" was easily a Top 10 episode of Community for me, given the way it handled some difficult situations. It was the ultimate family episode of Community, because this study group and these actors and these writers and these crew members are part of a family. It's a family like any other family, full of dysfunction, full of secrets, full of mutual admiration. A family that sometimes has to say goodbye to its own. In "Cooperative Polygraphy," we said goodbye to Pierce, and we began our farewell hugs with Troy. And we laughed and cried along the way, because that's what families do. Guys, I'm an emotional wreck!
– This season's amazing guest list continued this week, with Walton Goggins playing Mr. Stone. But Goggins didn't play the role for laughs, letting the group be the focus. That is, until the hilarious end tag, which made his appearance totally worth it.
– Annie: "I guess I knew Pierce was part of a weird futuristic cult, but I wasn't prepared for a funeral with so much beeping."
– Chang mouthing out his trademark "GaaaaaaaaaaYYYYYYYY!" during Mr. Stone's line of questioning of Jeff's heterosexuality.
– Chang's departure after being asked if he'd masturbated in the study room was absolutely perfect, as was his return with the admission that he masturbated "everywheeeeeeere!" Ken Jeong is a master of both the subdued and extravagant.
– Though this episode will draw comparisons to "Cooperative Calligraphy," I also picked up some of the rite-of-passage feelings of "Mixology Certification," Troy's birthday episode.
– Troy: "Troy Barnes. Doh, I meant to say Butts Carlton." Also, he tried to "pass" on a question. Haha, Troy has been awesome this season.
– Troy and Abed's handshake was ripped off of YouTube? I don't even know what is real and what isn't anymore.
– Pierce died the way he lived... a total jack-off.
– Upon hearing Troy is leaving, Abed: "Cool, cool, cool." Lie detector lady: "That's a lie." Oof. That one hurt.
- Comments (143)
DominykasKeru Jan 25, 2014
It is one of the best episodes in a a long time. it is in top 10 along with remedial chaos theory... And its rated 6,6.. WTF? Why the ratings of communitys new episodes are so low. Is somoene sabotaging the ratings on purpose?
alcalde Mar 17, 2014
It just wasn't that funny. It's like they're doing paint-by-number with old Community episodes.
TonyMutu Feb 28, 2014
Actually, all of Community's episodes are between 6 and 7. Just ignore it.
tobsh Jan 20, 2014
Awesome. I agree with you, this was definitely top 10 material. You know an episode is good when you gotta go and rewatch the whole thing just to get a shot at another 10% of jokes.
Pyke_ Jan 19, 2014
Britta got a Ipod...but wait! She´s already have an Ipod! Check the episode "Remedial Chaos Theory". Yeah I know about the reference of 1x22 episode...
Bloodangel Jan 19, 2014
Loved this episode......expect the constant lie detector informant saying 'that's a lie' constantly
dragon755 Jan 19, 2014
Chang is back and ... I ... LOVE IT!
Girlfriend left Community at the start of season 4 claiming it was too boring to continue. Showed her Chang's 10 second scene. Safe to say she'll be watching next week.
ILoveTVandDDsBB Jan 19, 2014
I fear for Abed and Troy better watch his back with Boyd Crowder around. All in all this was a hilarious and sperm filled episode.
bluemorphotat Jan 19, 2014
I am so happy Community is back... (chokes)
numberonecubsfa Jan 18, 2014
That episode was more like it. Character based humor. I'm annoyed they killed off Pierce after giving him an out that none the less allows him to come back some time if they choose. But at least it lead to a sweet episode and was at least treated with respect in the end.
Hungry_Homer111 Jan 18, 2014
I read in an interview with Dan Harmon on IGN that the agreement Chevy had with Sony/NBC when he left meant that he legally couldn't work on the set of the show again, hence why they had the hologram version of him (they could film that in a different location. Shooting in a separate location worked well then, but I don't think it work well if they did it more often, so killing him off didn't really change his chances of returning.
dragon755 Jan 19, 2014
I think this episode, (plus the hologram and the fact that Pierce has had a strong presence this season despite barely appearing) is a strong sign that Harmon is basically apologising to Chevy on behalf of NBC. There's no doubt that Harmon would have him back if possible but evidently it's not. At least Harmon (and us) had a chance to say a proper goodbye to Pierce/Chevy like he deserve.
Hopefully Harmon can continue his winning streak and give us the Community we missed, despite the hole Chevy and soon Glover has left behind.
It's also good to see a show deal with two major actors leaving in a proper mature way that rewards the audience.
adamonfire Jan 18, 2014
Great episode, and certainly shot the show back up to my first-to-watch spot of the Thursday shows.
joshzimmerman Jan 18, 2014
The fact that they did an entire episode literally consisting of them sitting in a single room talking while still being hysterical and heartfelt shows that Community is officially back! Now we just need the ratings to go up so we get another season and a movie! Best episode in a long time.
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Cisco Systems (CSCO) is scheduled to report fourth quarter results after the market close on Wednesday, August 13, with a conference call scheduled for 4:30 pm ET. Cisco, a member of the Dow Jones Industrial Average, sells Internet protocol-based networking and other products related to the communications and IT industry and provides related services. EXPECTATIONS: Analysts are looking for earnings per share of 53c on revenue of $12.14B, according to First Call. The consensus range for EPS is 51c-54c on revenue of $11.8B-$12.25B. Along with its last quarterly report, Cisco guided to Q4 adjusted EPS of 51c-53c and said it expects its revenue to be down 1% to 3% in the quarter compared to the prior year. At that time, the company also said it sees its FY14 adjusted EPS to come in at the higher end of its previously communicated $1.95-$2.05 range. LAST QUARTER: On May 14, Cisco reported third quarter adjusted EPS of 51c, beating the consensus analyst forecast of 48c. It's revenue came in at $11.5B, topping the $11.38B consensus forecast. Cisco reported a Q3 adjusted gross margin of about 62.7%. NEWS: On June 17, Cisco announced its intent to acquire privately held Tail-f Systems, whose products help service providers and enterprise IT organizations easily and cost-effectively implement applications, network services and solutions across networking devices. Upon completion of the acquisition, which is expected to be complete in Q4, Tail-f employees will join Cisco's Cloud and Virtualization Group. About two weeks later, tech blog Gigaom reported that Cisco has acquired British firm Assemblage for technology that uses real-time collaboration that does not require the user to download programs or plug-ins. On July 15, Cisco announced a multi-year sales and go-to-market agreement with Microsoft (MSFT) designed to modernize data centers through the delivery and acceleration of integrated solutions. Cisco and Microsoft will both invest in sales, marketing and engineering resources to drive global alignment, while delivering deeper technology integration across cloud and data center markets, the companies stated. STREET RESEARCH: On May 21, Northland said that after speaking with Cisco's management and attending Cisco Live, the firm believed that the company is taking share form Arista Networks (ANET), which has since come public. The firm added that it did not believe that Juniper (JNPR) has gained traction in data center switching and it recommended Cisco as a cyclical recovery play and a relative bargain to peers. About a week later, Deutsche Bank upgraded its rating on Cisco shares to Buy from Hold, citing expectations that the company's new product ramps in FY15 and FY16 will be stronger than expected. Deutsche said then that it saw upside to consensus estimates and raised its price target for Cisco shares to $30 from $25. On July 28, Pacific Crest downgraded its rating on Cisco shares to Sector Perform from Outperform, citing valuation and concern that the company's margin expansion could moderate in 2015. The firm believes Cisco shares are fairly valued at $26. Less than a week ago, Morgan Stanley said its checks indicate the enterprise market is improving. The firm said it expects Cisco's outlook to be conservative and said concerns over rapid software-defined networking adoption and margin impact are overblown. Morgan Stanley has an Overweight rating with a $30 price target on Cisco. PRICE ACTION: In the last three months, Cisco has advanced about 9.5%. In afternoon trading ahead of tonight's report, Cisco shares are down 0.5% to $25.01.
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Less than 150 games needed to reach our MobyGoal of 1,500 documented arcade titles!
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From the NJDC: Senator Rand Paul's membership in the Senate Foreign Relations Committee should be raising red flags and provoking severe concern across the pro-Israel community. The decision by Republican Senate leaders to give a bigger microphone and a prominent platform to someone who has repeatedly called for an end to U.S. aid to Israel and used his leadership PAC to push an anti-foreign aid agenda is simply outrageous. As we've said for months, Senator Paul and his father's acolytesa re becoming legitimate forces in today's Republican Party—and pro-Israel Republicans have repeatedly and epically failed to address this growing issue within the GOP ranks. Now this failure has very real consequences. The overwhelmingly pro-Israel American public deserves much better than a radical ideologue on the Senate's primary diplomatic committee who has demonstrated a singular obsession with slashing aid to the Jewish state.
NJDC Hits GOP for 'Outrageously' Placing Rand Paul on FR Committe
2 Comments.
Wow, Rand Paul does something good for a change…
Senator Rand has proposed eliminating foreign aid to all countries, not just Israel. Additionally, he said that Israel wouldn't be one of the last countries that he would remove aid from as he views Israel as an ally. Maybe you should get your facts straight before posting this nonsense. It's time for Israel to stand on her own. The US is broke and cannot afford to keep giving money to other countries to buy US weapons. Israel does not need our help to defend itself. They are more powerful than every other ME country combined. Foreign aid is a detriment as it forces countries to rely on us for help rather than standing up on their own.


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Matt Way, Joe's Dad Said; 'This was a great opportunity to give something back to Tom and support one of Newquay's surfers to develop within the sport he loves. This will also give Joe's paddle a lot of coverage at all of the surfing competitions and help to boost the popularity of this, now annual event"


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Stamford News
Local news for Stamford, CT continually updated from thousands of sources on the web.
3 hrs ago | News Times
Susan Elizabeth Phillips set for two CT book tour stops
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Stamford CEO Who Kicked Dog In Canada Apologizes For Actions
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Police: Stamford Man Suspects Female Acquaintance Stole Mom's Jewelry
About $34,000 of jewelry was stolen from a Southfield Avenue home and the owner has a suspect - a woman her son barely knew who was acting suspiciously at the home Aug. 11, police said.
Stamford News Video
Stamford News, Events & Info
Updated: Wed Aug 27, 2014 03:15 pm
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Erdinger Weissbier Kristallklar - Erdinger Weissbräu
Displayed for educational use only; do not reuse.
Ratings: 215 | Reviews: 121 | Display Reviews Only:
1.95/5 rDev -45.5%
Bottle into Erdinger Weisbier pint glass (how apt!). My bottle displays its name as simply "Kristall", but the ABV and labels match.
A: Pours a hazy but transparent yellow-gold with a thin head of fair retention and little cream. Generally appealing.
Sm: Musty one-note scent of malted barley. A poor aroma, but thankfully a light one.
T: As lacking as the smell. One empty open to a single generic note of barley with a lacking finish. Poorly balanced and poorly constructed. A bit of vanilla on the finish - strange for this style.
Mf: Lumpy. No joke. Far too heavy on the tongue for how little flavour its taste contains. A bit overcarbonated. Too smooth. It's almost got the thickness of syrup without the sweetness. Alarmingly dense. By far the worst part of this beer (and hitherto the worst characteristic of any Erdinger brew I've ever tasted). There's a hint of coarseness on the finish which is kind of nice.
Dr: Won't buy it again, won't have it again, won't speak of it again. A damned disappointment for Erdinger. Not bad tasting, just empty. It should be said that it hides its ABV well, however
01-16-2011 20:00:22 | More by kojevergas
2/5 rDev -44.1%
01-26-2012 02:06:33 | More by Tagsg
2.13/5 rDev -40.5%
This is a disappointment. A real yawner from an otherwise very good brewery. In removing the yeast they've also removed all the rest of the character. Almost no aroma, very little flavor. Light head and very little lace. The body isn't too good either. Very sharp hard carbonation in the mouth. It's just beer. That's it and that's that.
09-15-2007 01:49:34 | More by drpimento
2.25/5 rDev -37.2%
07-30-2014 13:00:41 | More by atrocity
2.35/5 rDev -34.4%
This tastes like a German's take on a Bud Light with more wheat. Pours fizzy yellow with an oversized white head. Corn, wheat, sugar, and metal in the aroma. Wheat with very little bubblegum and clove flavors which quickly disappear for a lager-like finish.
12-08-2008 22:36:10 | More by magictrokini
United Kingdom (England)
2.4/5 rDev -33%
Tastes more lagery than anything like a wheat beer, their regular wheat isn't that flavourful anyway, so why the hell would you want to drink a filtered version of it, kind of tasted a bit artificial aswell.
08-12-2002 01:47:09 | More by rastaman
2.5/5 rDev -30.2%
10-07-2013 21:23:09 | More by Whiskeydeez
2.58/5 rDev -27.9%
After pouring this brew in a glass it had a golden hue with tight white foam. After that it was all down hill. Where was the wheat? It had no bitter taste, but it like drinking a type of lager with no flavor. Pleasent after taste, but after taste of what? First and last time! Where's the Wheat??????
08-23-2002 13:40:56 | More by BeerManDan
2.68/5 rDev -25.1%
Bottle poured into weizen
Four finger soapy head, and just like they say, "crystal clear."
Smell: malt, not much else
Taste: Barely anything except wet grass.
Mouthfeel: Watery!!
This is the weakest beer in Erdinger's portfolio. I wouldn't recommend it. Try Urweisse or the Dunkel, if you want something different. I may try this again, but only if on tap.
06-07-2012 21:45:43 | More by BierStein711
2.68/5 rDev -25.1%
Pours a slightly hazy golden yellow/ripe banana color with clear edges and a 2.5 finger fizzy bubbly head that slowly dissolves. This bear isn't very "clear" at all actually. It's a little less hazy than a regular German wheat beer but is still kind of dark and cloudy.
Earthy aroma with subtle hops, citrus peel, clove and ripe banana aroma. All of these scents are very faint and much less prominent than in other German wheat beers. Kind of smells like a bland version of the style with some dirt thrown in.
Pretty carbonated for the style that adds a pleasant effervescence. Watered down light body with slight earthy hops and citrus peel. Decent amount of clove spice and a good amount of ripe banana.
This beer is a bland version of a style that I usually love. Kind of disappointing really but good for pounding down in the warmer months.
09-25-2009 06:19:16 | More by corby112
2.75/5 rDev -23.2%
06-26-2014 01:57:16 | More by patre_tim
2.75/5 rDev -23.2%
05-15-2013 01:07:08 | More by jgammoniv
2.8/5 rDev -21.8%
A- beautiful golden clear body with billowy head and mots of carbonation
S- Malthus and a little skunky. Smells like a euro lager.
T- hmmm this one is tough to rate. Some malt and grain notes. Some weird off taste in the back of my pallet that I cant distinguish except its not pleasant.
M- acceptable for the style
O- disappointed with this german offering. Don't care to try again.
07-13-2012 00:35:36 | More by bubseymour
New Jersey
2.8/5 rDev -21.8%
Poured clear and light yellow color. Nice inch and a half white head. Diminished quickly with next to no lacing.
Smells like bread or dough. Very faint however.
Tastes like yeast and faint banana. Not much depth of flavor. Very short finish.
Moderate carbonation and a very thin mouthfeel.
I might drink this beer after mowing my lawn on a really hot day, but that is about the only time.
11-07-2007 02:26:06 | More by brantadid
2.8/5 rDev -21.8%
Side-by-side comparison with their hefeweizen... half-liter German bottle, unpasteurized with a near-expired freshness date. The beer is crystal-clear gold, with lots of carbonation and three fingers of white head that retains well and laces nicely. Lightly sweet in the nose, with fruits, bubblegum and hints of wheat. The flavor is very fruity, with bubblegum, bready malts, and some late grassy hops. It has a light, dry, not-quite-tingly body that leaves a short finish. Interesting - tastes decent but doesn't really remind me a whole lot of a kristall. As to the comparisons with the hefe, this one looks much better, but the other tastes more authentic. Neither are great, and they both garnered the same score (granted for different reasons), but the prices are low enough to consider sampling them.
04-21-2008 20:40:42 | More by mmmbeer
2.9/5 rDev -19%
500ml bottle pours a beautiful clear canary color with a huge, rocky, white head that sticks around forever before fading to ring and sheet lacing. Very impressive to view. Aroma is, well, hmmm. If there is an aroma, it's faint hints of grass and pale malts. Mouthfeel is average, being light bodied and very carbonated. Taste is puzzling. Basically, there is none to speak of, other than faint lemony citrus, wheat, and something metallic. It's very refreshing, for sure, and is easily drinkable with no offnotes. Very disappointing considering how impressive it looks in the glass. I could easily guzzle a few of these, if I were thirsty, but I could satisy my thirst a lot cheaper with Miller Lite or water.
02-06-2004 21:45:21 | More by merlin48
2.9/5 rDev -19%
A- Pours a clear golden yellow, with a large foamy white head and light lacing
S- A slight fruit smell and somewhat bready.
T/M- Taste starts out like a lager with a hops and malt, but finishes with a wheat aftertaste. The beer seems to be a little overly carbonated.
D- This was not bad; I have others from the brewery that was better. Would not turn it down, but would not go out and buy it again.
02-19-2008 02:32:08 | More by monkeybeer
2.95/5 rDev -17.6%
Vibrant pale gold pour, with a large but quickly fading head.
Light aroma, hints of pears and banana, some spicy noble hops, but really quite faint.
Flavours are similarly faint, some bready wheat and the slightest banana, with some grainy malt creeping in as well.
Carbonation is way over the top. Very prickly.
11-26-2009 09:09:03 | More by CrazyDavros
3/5 rDev -16.2%
Poured from a 500 ml. bottle into a weizen glass. Pours a clear golden straw with a full inch plus of soapy white head. Head settles slowly and throws off some good lacing.
Nose has wheat and yeast on the nose but is otherwise lacking for the style. A bit of ripe banana exists but is well hidden and subtle and comes with a bit of cloaking malts. A perky carbonation continues. Some noble hops and wheat hide a lager like sense. Feel is more full bodied however giving the beer a decent feel and drink. Unexciting in the taste department, this beer is a bit of a wanderer. Think Weihenstephaner.
08-25-2009 06:59:18 | More by HalfFull
3/5 rDev -16.2%
01-03-2013 10:12:49 | More by AnitaBrewski
3/5 rDev -16.2%
05-28-2014 06:45:22 | More by KevMo84
3/5 rDev -16.2%
05-31-2013 07:11:00 | More by Luiz0930
New York
3/5 rDev -16.2%
08-08-2013 01:06:37 | More by John_Squires
3/5 rDev -16.2%
05-25-2014 16:58:46 | More by Shandycan
South Africa
3/5 rDev -16.2%
11-15-2011 09:28:24 | More by Thehuntmaster
Erdinger Weissbier Kristallklar from Erdinger Weissbräu
81 out of 100 based on 215 ratings.


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Release Date: November 24, 2010
Disney has been out of the fairy tale business for a while, but as they revamp their animation production, it looks like they're pulling themselves back in.
In this CG feature, the studio tackles the classic story of Rapunzel, the princess who has spent all her life in a tower and has grown a wicked long set of blonde hair.
Metajokes and snark have become a requirement for animated fairy tales this decade, and Disney will have an interesting challenge on their hands in trying to convince audiences that movies like these can still be made with earnest attitudes.
Ten women who kick butt and look good doing it!
Discover the 50 best films that made the jump from the small screen to the big screen!
Get ready for The Twilight Saga: Eclipse!
Actors that started their careers big and became Hollywood's biggest names!


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Research Topics
Genomes and Genes
Summary: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
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Publications340 found, 100 shown here
- Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trialsColin Baigent
CTSU, Oxford University, Oxford, UK
Lancet 373:1849-60. 2009Low-dose aspirin is of definite and substantial net benefit for many people who already have occlusive vascular disease. We have assessed the benefits and risks in primary prevention.
- Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trialsPeter M Rothwell
Stroke Prevention Research Unit, Department of Clinical Neurology, University of Oxford, Oxford, UK
Lancet 377:31-41. 2011Treatment with daily aspirin for 5 years or longer reduces subsequent risk of colorectal cancer...
- Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signalsCharles N Serhan
Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
J Exp Med 196:1025-37. 2002b>Aspirin (ASA) is unique among current therapies because it acetylates cyclooxygenase (COX)-2 enabling the biosynthesis of R-containing precursors of endogenous antiinflammatory mediators...
- Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trialJonathan Mant
Primary Care Clinical Sciences, University of Birmingham, Birmingham, UK
Lancet 370:493-503. 2007..We assessed whether warfarin reduced risk of major stroke, arterial embolism, or other intracranial haemorrhage compared with aspirin in elderly patients.
- Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trialsPeter M Rothwell
Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, UK
Lancet 379:1602-12. 2012Daily aspirin reduces the long-term risk of death due to cancer...
- Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trialS Connolly
Health Research Institute, Hamilton, ON, Canada
Lancet 367:1903-12. 2006..However, long-term monitoring is necessary and many patients cannot achieve optimum anticoagulation. We assessed whether clopidogrel plus aspirin was non-inferior to oral anticoagulation therapy for prevention of vascular events.
- Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivationYee Ping Sun
Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Biol Chem 282:9323-34. 2007..stereochemistry of the conjugated double bonds and chirality of alcohols present in resolvin D1 (RvD1) and its aspirin-triggered 17R epimer (AT-RvD1) with compounds prepared by total organic synthesis...
- Aspirin intake and survival after breast cancerMichelle D Holmes
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
J Clin Oncol 28:1467-72. 2010Animal and in vitro studies suggest that aspirin may inhibit breast cancer metastasis. We studied whether aspirin use among women with breast cancer decreased their risk of death from breast cancer.
- Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trialsPeter M Rothwell
Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, UK
Lancet 379:1591-601. 2012Daily aspirin reduces the long-term incidence of some adenocarcinomas, but effects on mortality due to some cancers appear after only a few years, suggesting that it might also reduce growth or metastasis...
- Clopidogrel with or without omeprazole in coronary artery diseaseDeepak L Bhatt
Veterans AffairsBoston Healthcare System, Brigham and Women s Hospital, Boston, MA 02132, USA
N Engl J Med 363:1909-17. 2010..Recently, concerns have been raised about the potential for PPIs to blunt the efficacy of clopidogrel...
- Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptorMauro Perretti
1 Department of Biochemical Pharmacology, William Harvey Research Institute, Bart s and the London School of Medicine, Queen Mary University of London, Charterhouse Square, London, UK 2 M P and N C contributed equally to this paper
Nat Med 8:1296-302. 2002b>Aspirin (ASA) and dexamethasone (DEX) are widely used anti-inflammatory agents yet their mechanism(s) for blocking polymorphonuclear neutrophil (PMN) accumulation at sites of inflammation remains unclear...
- Aspirin and cancer risk: a quantitative review to 2011C Bosetti
Department of Epidemiology, Istituto di Ricerche Farmacologiche, Mario Negri, Milan, Italy
Ann Oncol 23:1403-15. 2012b>Aspirin has been associated to a reduced risk of colorectal and possibly of a few other common cancers.
- Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cellsHaider Raza
Department of Biochemistry, Faculty of Medicine and Health Sciences, UAE University, POBox 17666, Al Ain, United Arab Emirates
Eur J Pharmacol 668:15-24. 2011It is widely accepted that non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, reduce the risk of cancer...
- Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trialsGiorgia De Berardis
Department of Clinical Pharmacology and Epidemiology, Consorzio Mario Negri Sud, Via Nazionale 8 A, 66030 S Maria Imbaro, Italy
BMJ 339:b4531. 2009To evaluate the benefits and harms of low dose aspirin in people with diabetes and no cardiovascular disease.
- Aspirin and cancer: has aspirin been overlooked as an adjuvant therapy?R E Langley
MRC Clinical Trials Unit, London, UK
Br J Cancer 105:1107-13. 2011b>Aspirin inhibits the enzyme cyclooxygenase (Cox), and there is a significant body of epidemiological evidence demonstrating that regular aspirin use is associated with a decreased incidence of developing cancer...
- Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survivalXiaoyun Liao
Department of Medical Oncology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA
N Engl J Med 367:1596-606. 2012Regular use of aspirin after a diagnosis of colon cancer has been associated with a superior clinical outcome...
- Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cellsFarhat V N Din
Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council Human Genetics Unit, Western General Hospital Edinburgh, United Kingdom
Gastroenterology 142:1504-15.e3. 2012b>Aspirin reduces the incidence of and mortality from colorectal cancer (CRC) by unknown mechanisms. Cancer cells have defects in signaling via the mechanistic target of rapamycin (mTOR), which regulates proliferation...
- Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statementJack Cuzick
Cancer Research UK Centre for Epidemiology, Mathematics, and Statistics, Queen Mary University of London, London UK
Lancet Oncol 10:501-7. 2009Evidence clearly shows a chemopreventive effect for aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) on colorectal cancer and probably other cancer types; however, data on the risk-benefit profile for cancer prevention ..
- Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trialHisao Ogawa
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto City, 860 8556, Japan
JAMA 300:2134-41. 2008Previous trials have investigated the effects of low-dose aspirin on primary prevention of cardiovascular events, but not in patients with type 2 diabetes.
- Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasisCharles N Serhan
Department of Anesthesiology, Perioperative and Pain Medicine, Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Prostaglandins Other Lipid Mediat 73:155-72. 2004..b>Aspirin treatment impacts biosynthesis of these compounds and a related series by triggering endogenous formation of the ..
- Stroke with intermittent atrial fibrillation: incidence and predictors during aspirin therapy. Stroke Prevention in Atrial Fibrillation InvestigatorsR G Hart
Department of Medicine, University of Texas Health Science Center, San Antonio 78284, USA
J Am Coll Cardiol 35:183-7. 2000..This study was performed to characterize the risk of stroke in elderly patients with recurrent intermittent atrial fibrillation (AF)...
- Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statinsMatthew Spite
Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Circ Res 107:1170-84. 2010..Here, we overview and update the biosynthesis and actions of proresolving lipid mediators, highlighting their diverse protective roles relevant to vascular systems and their relation to aspirin and statin therapies.
- Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trialsPeter M Rothwell
Stroke Prevention Research Unit, Department of Clinical Neurology, University of Oxford, Oxford, UK
Lancet 376:1741-50. 2010High-dose aspirin (≥500 mg daily) reduces long-term incidence of colorectal cancer, but adverse effects might limit its potential for long-term prevention. The long-term effectiveness of lower doses (75-300 mg daily) is unknown...
- Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trialsAnnemijn M Algra
Stroke Prevention Research Unit, University Department of Clinical Neurology, University of Oxford, Oxford, UK
Lancet Oncol 13:518-27. 2012Long-term follow-up of randomised trials of aspirin in prevention of vascular events showed that daily aspirin reduced the incidence of colorectal cancer and several other cancers and reduced metastasis...
- Reduced expression of COXs and production of prostaglandin E(2) in patients with nasal polyps with or without aspirin-intolerant asthmaJordi Roca-Ferrer
Immunoallergia Respiratoria Clinica i Experimental, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Barcelona, Spain
J Allergy Clin Immunol 128:66-72.e1. 2011Researchers have debated whether regulation of the COX enzymes (COX-1 and COX-2), which mediate production of prostaglandins (PGs), affects the pathogenesis of nasal polyps (NPs) and aspirin-intolerant asthma (AIA).
- Interindividual variability in the response to oral antiplatelet drugs: a position paper of the Working Group on antiplatelet drugs resistance appointed by the Section of Cardiovascular Interventions of the Polish Cardiac Society, endorsed by the Working Wiktor Kuliczkowski
3rd Department of Cardiology, Silesian Center for Heart Diseases, Zabrze, Poland
Eur Heart J 30:426-35. 2009..The efficacy of acetylsalicylic acid (ASA, aspirin) and clopidogrel in decreasing the risk of adverse events in coronary heart disease patients has been well ..
- Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillationMorten L Hansen
Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65 2900, Hellerup, Copenhagen, Denmark
Arch Intern Med 170:1433-41. 2010..Patients with atrial fibrillation (AF) often require anticoagulation and platelet inhibition, but data are limited on the bleeding risk of combination therapy...
- A new combined test with flowcytometric basophil activation and determination of sulfidoleukotrienes is useful for in vitro diagnosis of hypersensitivity to aspirin and other nonsteroidal anti-inflammatory drugsM L Sanz
Department of Allergology and Clinical Immunology, University of Navarra, Pamplona, Spain
Int Arch Allergy Immunol 136:58-72. 2005..We assessed whether nonsteroidal anti-inflammatory drugs (NSAIDs) may provoke blood basophil activation in vitro in aspirin- and NSAID-hypersensitive patients, as detected by a flowcytometric technique using the CD63 marker--..
- Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: a meta-analysisEmmanuel Bujold
Department of Obstetrics and Gynecology, Faculty of Medicine, Laval University, Quebec, Canada
Obstet Gynecol 116:402-14. 2010To estimate the effect of low-dose aspirin started in early pregnancy on the incidence of preeclampsia and intrauterine growth restriction (IUGR).
- Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trialJohn Burn
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK
Lancet 378:2081-7. 2011Observational studies report reduced colorectal cancer in regular aspirin consumers. Randomised controlled trials have shown reduced risk of adenomas but none have employed prevention of colorectal cancer as a primary endpoint...
- Effects of low-dose aspirin on acute inflammatory responses in humansThea Morris
Division of Medicine, University College London, Centre for Clinical Pharmacology and Therapeutics, London, United Kingdom
J Immunol 183:2089-96. 2009b>Aspirin is a unique nonsteroidal anti-inflammatory drug; at high doses (aspirin(high), 1g), it is anti-inflammatory stemming from the inhibition of cyclooxygenase and proinflammatory signaling pathways including NF-kappaB, but is ..
- Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET studyPaul A Gurbel
Sinai Center for Thrombosis Research, Cardiac Catheterization Laboratory, 2401 W Belvedere Ave, Baltimore, MD 21215, USA
Circulation 120:2577-85. 2009..This is the first study to compare the onset and offset of platelet inhibition (IPA) with ticagrelor using the PLATO (PLATelet inhibition and patient Outcomes) trial loading dose (180 mg) with a high loading dose (600 mg) of clopidogrel...
- Platelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatmentDominick J Angiolillo
Division of Cardiology, University of Florida, Shands Jacksonville, 655 West 8th St, Jacksonville, FL 32209, USA
Diabetes 54:2430-5. 2005To assess platelet function profiles in diabetic and nondiabetic patients on aspirin and clopidogrel therapy, two patient populations were included to investigate the 1) acute effects of a 300-mg clopidogrel loading dose (group 1, n = 52)..
- EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivityE Nizankowska-Mogilnicka
Department of Medicine, Jagiellonian University School of Medicine, Krakow, Poland
Allergy 62:1111-8. 2007b>Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most common causes of adverse drug reactions. Majority of them are of the hypersensitivity type...
- Aspirin "resistance" and risk of cardiovascular morbidity: systematic review and meta-analysisGeorge Krasopoulos
University Health Network, Division of Cardiovascular Surgery, Toronto General Hospital
BMJ 336:195-8. 2008To determine if there is a relation between aspirin "resistance" and clinical outcomes in patients with cardiovascular disease.
- Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studiesEnrico Flossmann
Stroke Prevention Research Unit, University Department of Clinical Neurology, Radcliffe Infirmary, Oxford OX2 6HE, UK
Lancet 369:1603-13. 2007Randomised trials have shown that aspirin reduces the short-term risk of recurrent colorectal adenomas in patients with a history of adenomas or cancer, but large trials have shown no effect in primary prevention of colorectal cancer ..
- Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndromeHollis R O'Neal
Department of Medicine, Section of Pulmonary and Critical Care Medicine, Louisiana State University Health Sciences Center, Baton Rouge, LA, USA
Crit Care Med 39:1343-50. 2011..We also investigated the effect of combined prehospital use of both statins and aspirin.
- Aspirin or enoxaparin thromboprophylaxis for patients with newly diagnosed multiple myeloma treated with lenalidomideAlessandra Larocca
Myeloma Unit, Division of Hematology, University of Torino, Azienda Ospedaliero Universitaria AOU S Giovanni Battista, Torino, Italy
Blood 119:933-9; quiz 1093. 2012..randomized substudy of a phase 3 trial compared the efficacy and safety of thromboprophylaxis with low-dose aspirin (ASA) or low-molecular-weight heparin (LMWH) in patients with newly diagnosed MM, treated with lenalidomide and ..
- Effect of aspirin and NSAIDs on risk and survival from colorectal cancerFarhat V N Din
Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK
Gut 59:1670-9. 2010Previous studies have shown that aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) lower colorectal cancer (CRC) risk. However, the lowest effective NSAID dose, treatment duration, and effects on survival are not defined...
- Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study)Michael D Ezekowitz
Lankenau Institute for Medical Research and The Heart Center, Wynnewood, PA, USA
Am J Cardiol 100:1419-26. 2007..to receive blinded doses of 50-, 150-, or 300-mg dabigatran twice daily alone or combined with 81- or 325-mg aspirin or open-label warfarin administered to achieve an international normalized ratio of 2 to 3 for 12 weeks...
- Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosisMarc I Chimowitz
Department of Neurology, School of Medicine, Emory University, Atlanta, USA
N Engl J Med 352:1305-16. 2005Atherosclerotic intracranial arterial stenosis is an important cause of stroke. Warfarin is commonly used in preference to aspirin for this disorder, but these therapies have not been compared in a randomized trial.
- Prevention of peptic ulcers with esomeprazole in patients at risk of ulcer development treated with low-dose acetylsalicylic acid: a randomised, controlled trial (OBERON)James M Scheiman
Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
Heart 97:797-802. 2011....
- Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levelsMeiling Lu
Cell Death Regulation Laboratory, Department of Medicine and Cell and Molecular Biology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Clin Cancer Res 14:3168-76. 2008..We examined whether the nonsteroidal anti-inflammatory drug aspirin sensitized cancer cells to TRAIL agonists in vitro and in vivo and investigated the underlying mechanism.
- Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activityByung Soo Kim
Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Sangrok Ku, Ansan, Gyeonggi Do, Korea
Pharmacogenet Genomics 20:748-58. 2010b>Aspirin affects interleukin-4 (IL-4) synthesis; however, the genetic role of IL-4 has not been evaluated in asthmatics with aspirin hypersensitivity...
- Association of PTGER gene family polymorphisms with aspirin intolerant asthma in Korean asthmaticsByung Lae Park
Department of Life Science, Sogang University, Seoul, Korea
BMB Rep 43:445-9. 2010b>Aspirin-intolerant asthma (AIA) is characterized by severe asthmatic attack after ingestion of aspirin and/or non-steroidal anti-inflammatory drugs...
- The flow-cytometric determination of basophil activation induced by aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is useful for in vitro diagnosis of the NSAID hypersensitivity syndromeP Gamboa
Allergy Unit, Hospital Basurto, Bilbao, Spain
Clin Exp Allergy 34:1448-57. 2004..Today, it is still claimed that no in vitro diagnostic tests exist for that condition and that the only way to confirm the diagnosis is a provocation challenge...
- Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trialJoseph J Y Sung
Institute of Digestive Disease, Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong
Ann Intern Med 152:1-9. 2010It is uncertain whether aspirin therapy should be continued after endoscopic hemostatic therapy in patients who develop peptic ulcer bleeding while receiving low-dose aspirin.
- Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosisPatrick Andre
Millennium Pharmaceuticals, Inc, 256 E Grand Ave, South San Francisco, Calif 9408, USA
Circulation 108:2697-703. 2003..This study was designed to determine whether (1) P2Y12 antagonism synergizes with other antithrombotics and (2) anticoagulants (thrombin inhibitors) affect the antithrombotic activity elicited by P2Y12 antagonism...
- Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseasesT E Van Dyke
Department of Periodontology and Oral Biology, Boston University, Goldman School of Dental Medicine, 100 East Newton Street, Boston, MA 02118, USA
J Dent Res 82:82-90. 2003....
- Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammationN Chiang
Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
J Exp Med 191:1197-208. 2000Lipoxin (LX) A(4) and aspirin-triggered LX (ATL) are endogenous lipids that regulate leukocyte trafficking via specific LXA(4) receptors (ALXRs) and mediate antiinflammation and resolution...
- Prasugrel versus clopidogrel in patients with acute coronary syndromesStephen D Wiviott
Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
N Engl J Med 357:2001-15. 2007Dual-antiplatelet therapy with aspirin and a thienopyridine is a cornerstone of treatment to prevent thrombotic complications of acute coronary syndromes and percutaneous coronary intervention.
- Posttreatment with aspirin-triggered lipoxin A4 analog attenuates lipopolysaccharide-induced acute lung injury in mice: the role of heme oxygenase-1Sheng wei Jin
Department of Anesthesiology, Second Affiliated Hospital, Wenzhou Medical College, Wenzhou, China
Anesth Analg 104:369-77. 2007..We hypothesized that posttreatment with 15-epi-16-parafluoro-phenoxy lipoxin A4 (ATL) could attenuate lipopolysaccharide (LPS)-induced acute lung injury in mice...
- Clinical and pathologic perspectives on aspirin sensitivity and asthmaDonald D Stevenson
Division of Allergy, Asthma and Immunology and the Department of Medicine, Scripps Clinic and the Scripps Research Institute, La Jolla, USA
J Allergy Clin Immunol 118:773-86; quiz 787-8. 2006b>Aspirin and other nonsteroidal anti-inflammatory drugs that inhibit COX-1 induce unique nonallergic reactions, consisting of attacks of rhinitis and asthma...
- Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issuesMichael J Thun
Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, GA 30329 4251, USA
J Natl Cancer Inst 94:252-66. 2002..Finally, we suggest research opportunities that may help to accelerate the future clinical application of NSAIDs for cancer prevention or treatment...
- Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) studyPaul A Gurbel
Sinai Center for Thrombosis Research, Hoffberger Bldg, Suite 56, 2401 W Belvedere Ave, Baltimore, MD 21215, USA
Circulation 115:3156-64. 2007The antiplatelet effect of aspirin is attributed to platelet cyclooxygenase-1 inhibition...
- Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient dataLisa M Askie
Centre for Perinatal Health Services Research, University of Sydney, Sydney, Australia
Lancet 369:1791-8. 2007..Antiplatelet agents, especially low-dose aspirin, might prevent or delay pre-eclampsia, and thereby improve outcome...
- Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trialShamir R Mehta
McMaster University and Population Health Research Institute, Hamilton Health Sciences, Hamilton, ON, Canada
Lancet 376:1233-43. 2010Clopidogrel and aspirin are the most commonly used antiplatelet therapies for percutaneous coronary intervention (PCI)...
- Aspirin and extended-release dipyridamole versus clopidogrel for recurrent strokeRalph L Sacco
Miller School of Medicine, University of Miami, Miami, USA
N Engl J Med 359:1238-51. 2008Recurrent stroke is a frequent, disabling event after ischemic stroke. This study compared the efficacy and safety of two antiplatelet regimens--aspirin plus extended-release dipyridamole (ASA-ERDP) versus clopidogrel.
- Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependentFabiana S Machado
Department of Immunology, Duke University Medical Center, Durham, North Carolina 27705, USA
Nat Med 12:330-4. 2006Control of inflammation is crucial to prevent damage to the host during infection. Lipoxins and aspirin-triggered lipoxins are crucial modulators of proinflammatory responses; however, their intracellular mechanisms have not been ..
- Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirinSteen Husted
Department of Medicine and Cardiology, Arhus University Hospital, Denmark
Eur Heart J 27:1038-47. 2006..This double-blind, parallel-group study was conducted to assess the pharmacodynamics, pharmacokinetics, and safety of AZD6140, the first oral, reversible adenosine diphosphate (ADP) receptor antagonist...
- Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a population-based studyJ Hedman
Department of Respiratory Medicine, Tampere University Hospital, Finland
Int J Epidemiol 28:717-22. 1999..The prevalence and relation to asthma of aspirin intolerance, nasal polyposis, allergic rhinitis and smoking habits were also examined.
- Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitisAna R Sousa
Guy s, King s and St Thomas School of Medicine, London, United Kingdom
N Engl J Med 347:1493-9. 2002Patients with asthma who have aspirin sensitivity have greater cysteinyl leukotriene production and greater airway hyperresponsiveness to the effects of inhaled cysteinyl leukotrienes than their aspirin-tolerant counterparts...
- Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trialF Gerald R Fowkes
Centre for Population Health Sciences, University of Edinburgh, Scotland
JAMA 303:841-8. 2010..Screening for a low ABI can identify an asymptomatic higher risk group potentially amenable to preventive treatments...
- A randomized study assessing the impact of cilostazol on platelet function profiles in patients with diabetes mellitus and coronary artery disease on dual antiplatelet therapy: results of the OPTIMUS-2 studyDominick J Angiolillo
Division of Cardiology, University of Florida College of Medicine at Shands Jacksonville, Jacksonville, FL 32209, USA
Eur Heart J 29:2202-11. 2008..The aim of this pilot study was to assess the functional impact of cilostazol in T2DM patients on standard aspirin and clopidogrel treatment.
- Aspirin dose for the prevention of cardiovascular disease: a systematic reviewCharles L Campbell
Gill Heart Institute, University of Kentucky, Lexington, USA
JAMA 297:2018-24. 2007More than 50 million US adults take aspirin regularly for long-term prevention of cardiovascular disease, typically either 81 mg/d or 325 mg/d. Controversy remains regarding the most appropriate long-term daily dose.
- Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirinBrian F Gage
Division of General Medical Sciences, Washington University School of Medicine Campus Box 8005, 660 S Euclid Ave, St Louis, MO 63110, USA
Circulation 110:2287-92. 2004..Although adjusted-dose warfarin is superior to aspirin for reducing stroke in AF, the absolute risk reduction of warfarin depends on the stroke rate with aspirin...
- A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthmaCharisse Flerida A Pasaje
Department of Life Science, Sogang University, 1 Shinsu dong, Mapo gu, Seoul, 121 742, Republic of Korea
Immunogenetics 63:13-21. 2011b>Aspirin-intolerant asthma (AIA) is an asthma phenotype characterized by the development of bronchoconstriction following ingestion of aspirin...
- Prothrombotic and hemorrhagic effects of aspirinOmar Aguejouf
Laboratoire d Hématologie Université Victor Segalen Bordeaux 2, Bordeaux, France
Clin Appl Thromb Hemost 15:523-8. 2009b>Aspirin remains the most widely used drug for prevention of vascular events...
- Modulation of thiol homeostasis induced by H2S-releasing aspirinDaniela Giustarini
Department of Evolutionary Biology, Laboratory of Pharmacology and Toxicology, University of Siena, Siena, Italy
Free Radic Biol Med 48:1263-72. 2010The H(2)S-releasing aspirin (ACS14) containing a dithiolethione moiety has been demonstrated to maintain the thromboxane-suppressing activity of the parent compound, but it seems to spare the gastric mucosa by affecting redox imbalance ..
- Aspirin with or without an antiemetic for acute migraine headaches in adultsVaro Kirthi
Pain Research and Nuffield Department of Anaesthetics, University of Oxford, West Wing Level 6, John Radcliffe Hospital, Oxford, Oxfordshire, UK, OX3 9DU
Cochrane Database Syst Rev 4:CD008041. 2010..OBJECTIVES: To determine the efficacy and tolerability of aspirin, alone or in combination with an antiemetic, compared to placebo and other active interventions in the treatment ..
- Aspirin for preventing the recurrence of venous thromboembolismCecilia Becattini
Division of Internal and Cardiovascular Medicine and Stroke Unit, Department of Internal Medicine, University of Perugia, Perugia, Italy
N Engl J Med 366:1959-67. 2012..Extending anticoagulation prevents recurrences but is associated with increased bleeding. The benefit of aspirin for the prevention of recurrent venous thromboembolism is unknown.
- Oral anticoagulants vs aspirin in nonvalvular atrial fibrillation: an individual patient meta-analysisCarl van Walraven
Clinical Epidemiology Unit, Ottawa Health Research Institute, F 6, Ottawa Hospital, Civic Campus, 1053 Carling Ave, Ottawa, Ontario, Canada K1Y 4E9
JAMA 288:2441-8. 2002..Patients with nonvalvular atrial fibrillation (AF) have an increased risk of stroke and other vascular events...
- Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trialMarie Germaine Bousser
Hopital Lariboisiere, INSERM U, Paris Diderot University, France
Lancet 377:2013-22. 2011..We compared the selective thromboxane-prostaglandin receptor antagonist terutroban with aspirin in the prevention of cerebral and cardiovascular ischaemic events in patients with a recent non-cardioembolic ..
- The role of aspirin in cancer preventionMichael J Thun
Epidemiology Research Program, American Cancer Society, 250 Williams Street, Atlanta, GA 30303 1002, USA michael thun cancer org
Nat Rev Clin Oncol 9:259-67. 2012Clinical guidelines for prophylactic aspirin use currently only consider the cardiovascular benefits of aspirin, weighed against the potential harm from aspirin-induced bleeding...
- Early administration of low-dose aspirin for the prevention of preterm and term preeclampsia: a systematic review and meta-analysisStéphanie Roberge
Department of Social and Preventive Medicine, Universite Laval, Quebec City, Que, Canada
Fetal Diagn Ther 31:141-6. 2012To compare the effect of early administration of aspirin on the risk of preterm and term preeclampsia.
- Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responsesAlexandre P Rogerio
Pulmonary and Critical Care Medicine Division, Department of Internal Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Immunol 189:1983-91. 2012..In this study, we determined the impact of resolvin D1 (RvD1) and aspirin-triggered RvD1 (AT-RvD1) on the development of allergic airway responses and their resolution...
- Early treatment with aspirin plus extended-release dipyridamole for transient ischaemic attack or ischaemic stroke within 24 h of symptom onset (EARLY trial): a randomised, open-label, blinded-endpoint trialReinhard Dengler
Department of Neurology, Medizinische Hochschule Hannover, Hannover, Germany
Lancet Neurol 9:159-66. 2010..The EARLY trial aimed to compare outcome in patients given aspirin plus extended-release dipyridamole twice daily either within 24 h of stroke or TIA or after 7 days of aspirin ..
- Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarctionFook Hong Ng
Department of Medicine and Geriatric, Ruttonjee Hospital, Hong Kong, China
Am J Gastroenterol 107:389-96. 2012..in patients with acute coronary syndrome (ACS) or ST elevation myocardial infarction (STEMI) receiving aspirin, clopidogrel, and enoxaparin or thrombolytics...
- Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: nationwide propensity score matched studyMette Charlot
Department of Cardiology, Copenhagen University Hospital Gentofte, Post 635, Niels Andersens Vej 65, 2900 Hellerup, Denmark
BMJ 342:d2690. 2011To examine the effect of proton pump inhibitors on adverse cardiovascular events in aspirin treated patients with first time myocardial infarction.
- Aspirin, warfarin, or enoxaparin thromboprophylaxis in patients with multiple myeloma treated with thalidomide: a phase III, open-label, randomized trialAntonio Palumbo
University of Torino, Azienda Ospedaliero Universitaria San Giovanni Battista, Torino, Italy
J Clin Oncol 29:986-93. 2011..In this randomized, open-label, multicenter trial, we compared aspirin (ASA) or fixed low-dose warfarin (WAR) versus low molecular weight heparin (LMWH) for preventing thromboembolism ..
- NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenograftsKaruppaiyah Selvendiran
Davis Heart and Lung Research Institute and Comprehensive Cancer Center, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA
Cell Cycle 7:81-8. 2008We have previously reported the inhibitory effect of NCX-4016, a nitro derivative of aspirin, on the proliferation of cisplatin-resistant human ovarian cancer cells, in vitro (Bratasz et al., Proc Natl Acad Sci USA 2006; 103:3914-9)...
- Prevalence of aspirin and clopidogrel resistance among patients with and without drug-eluting stent thrombosisTina L Pinto Slottow
Division of Cardiology, Washington Hospital Center, Washington, District of Columbia, USA
Am J Cardiol 104:525-30. 2009..with a cohort of patients who had not would exhibit greater platelet reactivity and a greater prevalence of aspirin and clopidogrel resistance...
- Aspirin and recurrent intracerebral hemorrhage in cerebral amyloid angiopathyA Biffi
Department of Neurology and Hemorrhagic Stroke Research Program, Massachusetts General Hospital Stroke Research Center, Harvard Medical School, 175 Cambridge Street, Suite 300, Boston, MA 02114, USA
Neurology 75:693-8. 2010..To identify and compare clinical and neuroimaging predictors of primary lobar intracerebral hemorrhage (ICH) recurrence, assessing their relative contributions to recurrent ICH...
- Aspirin for the primary prevention of cardiovascular events in women and men: a sex-specific meta-analysis of randomized controlled trialsJeffrey S Berger
Department of Cardiovascular Medicine, Duke University, Durham, NC, USA
JAMA 295:306-13. 2006b>Aspirin therapy reduces the risk of cardiovascular disease in adults who are at increased risk. However, it is unclear if women derive the same benefit as men.
- Low-dose aspirin for prevention of stroke in low-risk patients with atrial fibrillation: Japan Atrial Fibrillation Stroke TrialHiroshi Sato
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan
Stroke 37:447-51. 2006..We examined the efficacy and safety of aspirin therapy in Japanese patients with NVAF in a prospective randomized multicenter trial.
- Low molecular weight heparin and aspirin for recurrent pregnancy loss: results from the randomized, controlled HepASA TrialCarl A Laskin
University of Toronto and LifeQuest Centre for Reproductive Medicine, Toronto, Canada
J Rheumatol 36:279-87. 2009..loss (RPL) and either autoantibodies or a coagulation abnormality, treated with low molecular weight heparin plus aspirin (LMWH/ASA) or ASA alone, and to place our results in context with other randomized clinical trials (RCT) with ..
- Effect of in vitro aspirin stimulation on basophils in patients with aspirin-exacerbated respiratory diseaseG E Celik
Ankara University School of Medicine, Division of Allergy, Ankara, Turkey
Clin Exp Allergy 39:1522-31. 2009Basophil activation has been implicated in the pathogenesis of aspirin-exacerbated respiratory disease (AERD)...
- Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean populationCharisse Flerida A Pasaje
Department of Life Science, Sogang University, Seoul, 121 742, Republic of Korea
Ann Hum Genet 74:326-34. 2010b>Aspirin-intolerant asthma (AIA) occurs from asthma exacerbation after exposure to aspirin. However, the underlying mechanisms of AIA occurrence are still unclear...
- The effect of aspirin desensitization on novel biomarkers in aspirin-exacerbated respiratory diseasesRohit K Katial
Division of Allergy and Immunology, National Jewish Health, Denver, CO 80206, USA
J Allergy Clin Immunol 126:738-44. 2010Patients with aspirin-exacerbated respiratory disease have been shown to benefit clinically from aspirin desensitization followed by chronic high-dose aspirin therapy. However, the mechanism of this phenomenon is still unclear.
- Duration of dual antiplatelet therapy after implantation of drug-eluting stentsSeung Jung Park
Department of Cardiology, Center for Medical Research and Information, University of Ulsan College of Medicine, Seoul, South Korea
N Engl J Med 362:1374-82. 2010..The potential benefits and risks of the use of dual antiplatelet therapy beyond a 12-month period in patients receiving drug-eluting stents have not been clearly established...
- Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular diseaseRehan Qayyum
Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Cardiol 101:1359-63. 2008Compared with men, women have greater platelet aggregation before and after low-dose aspirin. It is not known whether high-dose aspirin therapy brings residual platelet aggregation in women closer to that in men...
- Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stentsAnna Maria Gori
Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy
J Am Coll Cardiol 52:734-9. 2008This study sought to determine the incidence of aspirin nonresponsiveness in addition to clopidogrel nonresponsiveness and whether this association identifies patients at an increased risk of drug-eluting stent (DES) thrombosis.
- Interaction of inflammation, thrombosis, aspirin and enoxaparin in CNS experimental antiphospholipid syndromeDavid Tanne
Department of Neurology, Sheba Medical Center, Tel Hashomer, Israel Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Israel
Neurobiol Dis 30:56-64. 2008..eAPS) or adjuvant (controls) and treated daily from 1 month after immunization with either sham injections, aspirin (1.2 mg/kg) or enoxaparin (1 mg/kg) for 3 months...
- Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery diseaseE L Grove
Departments ofCardiology Clinical Biochemistry, Aarhus University Hospital, Skejby, Aarhus, Denmark
J Thromb Haemost 9:185-91. 2011Previous studies have demonstrated considerable variation in the antiplatelet effect of aspirin.
- Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndromeJohn Burn
Institute of Human Genetics, Newcastle University, International Centre for Life, Central Pkwy, Newcastle upon Tyne NE1 3BZ, United Kingdom
N Engl J Med 359:2567-78. 2008Observational and epidemiologic data indicate that the use of aspirin reduces the risk of colorectal neoplasia; however, the effects of aspirin in the Lynch syndrome (hereditary nonpolyposis colon cancer) are not known...
- Current use of aspirin and antithrombotic agents in the United States among outpatients with atherothrombotic disease (from the REduction of Atherothrombosis for Continued Health [REACH] Registry)Christopher P Cannon
TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 105:445-52. 2010Despite its proven efficacy, low cost, and wide availability, aspirin remains underused. We examined current aspirin use and determined factors that influence its use among outpatients in the United States (US)...
- Effect of statin drugs and aspirin on progression in open-angle glaucoma suspects using confocal scanning laser ophthalmoscopyDawn K De Castro
Department of Ophthalmology, University of California at San Francisco, San Francisco, California 94143 0730, USA
Clin Experiment Ophthalmol 35:506-13. 2007To determine the effect of statins and aspirin on the rate of progression of optic nerve parameters in open-angle glaucoma (OAG) suspects, as defined by confocal scanning laser ophthalmoscopy (CSLO).
- Aspirin induces gastric epithelial barrier dysfunction by activating p38 MAPK via claudin-7Tadayuki Oshima
Department of Internal Medicine and Bioregulation, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Am J Physiol Cell Physiol 295:C800-6. 2008..However, the mechanism by which aspirin affects the function of gastric epithelial tight junctions is unknown...
- First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studiesUdaya S Tantry
Sinai Center for Thrombosis Research, Cardiac Catheterization Laboratory, 2401 W Belvedere Ave, Baltimore, MD 21215, USA
Circ Cardiovasc Genet 3:556-66. 2010..The influence of cytochrome P450 (CYP) 2C19 genotype on platelet function in patients treated with ticagrelor versus clopidogrel is unknown...
- Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-kappa B and AP-1 activation, and IL-8 gene expression in human leukocytesLevente Jozsef
Research Center, Maisonneuve Rosemont Hospital and Department of Medicine, University of Montreal, Montreal, QC, Canada H1T 2M4
Proc Natl Acad Sci U S A 99:13266-71. 2002Lipoxin A(4) (LXA(4)) and aspirin-triggered 15-epi-LXA(4) (ATL) are emerging as endogenous braking signals for neutrophil-mediated tissue injury...
- A randomised controlled trial of warfarin versus aspirin for stroke prevention in octogenarians with atrial fibrillation (WASPO)Amar Rash
Northern General Hospital, Medicine for the Elderly, Sheffield, UK
Age Ageing 36:151-6. 2007..Although trials demonstrate reductions in stroke with warfarin, audit data show that it is still underused. However, anti-coagulation in the very elderly is not without risk...
Research Grants82
- Novel mechanisms by which aspirin might protect against atherosclerosisSampath Parthasarathy; Fiscal Year: 2010b>Aspirin ('acetylsalicylic acid') inhibits the formation of prostaglandins (PGs) that cause inflammation, swelling, pain and fever...
- A Clinical Trial of Aspirin and Simvastatin in Pulmonary Arterial HypertensionSteven Kawut; Fiscal Year: 2007..HMG-CoA reductase inhibitors (statins) and aspirin are very safe, highly-effective cardiovascular therapies used by millions of people...
- Aspirin and Simvastatin--Pulmonary Arterial HypertensionSteven Kawut; Fiscal Year: 2006..HMG-CoA reductase inhibitors (statins) and aspirin are very safe, highly-effective cardiovascular therapies used by millions of people...
- A Clinical Trial of Aspirin and Simvastatin in Pulmonary Arterial HypertensionSteven Kawut; Fiscal Year: 2009..HMG-CoA reductase inhibitors (statins) and aspirin are very safe, highly-effective cardiovascular therapies used by millions of people...
- Role of IRF3 and RXRa Crosstalk in Host Response to Viral InfectionsGenhong Cheng; Fiscal Year: 2010..metabolic diseases such as Reye's Syndrome, a hepatotoxicity disease that occurs when children are given aspirin in the context of a viral infection, or acetaminophen (APAP)-induced hepatotoxicity, which accounts for about ..
- Aspirin, Helicobacter Pylori, and Peptic Ulcer DiseaseEdward Lew; Fiscal Year: 2003b>Aspirin and other non-steroidal anti-inflammatory drugs are widely used to treat pain and inflammation, and at low doses, aspirin is also increasingly being used for cardiovascular prophylaxis...
- RANDOMIZED TRIALS OF VITAMIN SUPPLEMENTS AND EYE DISEASEWilliam Christen; Fiscal Year: 2002..The PHS is a randomized, double-blind, placebo-controlled trial of aspirin use in reducing cardiovascular disease, and beta-carotene in reducing cancer, among 22,071 male U.S...
- RANDOMIZED TRIALS OF VITAMIN SUPPLEMENTS AND EYE DISEASEWilliam Christen; Fiscal Year: 1993..The PHS is a randomized, double-blind, placebo-controlled trial of aspirin use in reducing cardiovascular disease, and beta-carotene in reducing cancer, among 22,071 male U.S...
- POLYMORPHISMS IN PG/COX PATHWAY AND COLORECTAL POLYPSCornelia Ulrich; Fiscal Year: 2003b>Aspirin and other non-steroidal inflammatory drugs (NSAIDs) reduce the recurrence of colorectal polyps among patients with familial adenomatous polyposis (FAP) and are associated with a lower risk of both adenoma and colorectal cancer...
- NO Releasing Aspirin and Colon Cancer ChemopreventionBasil Rigas; Fiscal Year: 2003..Current evidence suggests that they are much safer than traditional NSAIDs. Early studies indicate that an NO-aspirin (NO-ASA) derivative is much more effective than ASA in cultured cells and against colon preneoplastic lesions...
- NO Releasing Aspirin and Colon Cancer ChemopreventionBasil Rigas; Fiscal Year: 2005..Current evidence suggests that they are much safer than traditional NSAIDs. Early studies indicate that an NO-aspirin (NO-ASA) derivative is much more effective than ASA in cultured cells and against colon preneoplastic lesions...
- ANALGESIC USE AND THE RISK OF CHRONIC RENAL FAILUREGary Curhan; Fiscal Year: 2002..with consumption of large amounts of acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) but not aspirin. Since these analgesics are widely available and used, their association with renal dysfunction is particularly ..


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14 results for "30 for 30"
Kurt Snibbe's Page 2 cartoon caption contest winnerKurt Snibbe
Earlier today, we posted a blank cartoon and readers offered their captions. Our favorite was by commenter Late_Breaking_Opinion. Please check your ESPN.com profile message center for an email. Thanks for participating. Check back Monday for anothe...Blog | Conversation | March 30, 2012
Kurt Snibbe's Page 2 cartoon caption contestKurt Snibbe
Take a shot at writing a cartoon caption. Page 2 cartoonist Kurt Snibbe will offer up a blank cartoon each weekday morning, and he will fill in the blank with our favorite reader submission at the end of the business day. So please, by all means, sh...Blog | Conversation | March 30, 2012
Uni Watch: Here's the full 411 on the NBA's new jerseysPaul Lukas
Uni Watch has the "hole" truth on the NBA's uniform changes.Story | Conversation | September 23, 2010
Uni Watch: Which uniforms are in the most desperate need of a red...Paul Lukas
Uni Watch determines which pro teams' uniforms are in dire need of a makeover.Story | Conversation | June 30, 2009
Scoop Jackson: The Houston Rockets, and Yao Ming in particular, a...Scoop Jackson
With the latest Yao Ming injury news, you have to wonder: Are the Houston Rockets cursed?Story | Conversation | June 30, 2009
The greatest beatdowns in historyDavid Schoenfield
The Rangers' 30-3 victory over the Orioles has inspired Page 2 to come up with the 100 greatest beatdowns of all time.Story | Conversation | August 23, 2007
Yes, we're talkin' about practiceChuck Klosterman
Chuck Klosterman is coming to you live from the Georgia Dome with all the Final Four you can handle.Story | Conversation | March 30, 2007
Are we having serious fun yet?Patrick Hruby
Dave Raymond become famous as the Phillie Phanatic. Now he's teaching others how to be a mascot. It's not as easy you think, reports Patrick Hruby.Story | Conversation | November 30, 2006
Tuning in the NBA's big pictureBill Simmons
From worst to first, Bill Simmons breaks down who has a chance at walking away with the NBA crown.Story | Conversation | March 17, 2006
Around the NBA in 30 daysEric Neel
What a first month of NBA ball it has been! Eric wonders if it's been the craziest 30 days in NBA history.Story | Conversation | December 01, 2004
Sorting out the NBA PlayoffsBill Simmons
With the NBA Playoffs at full throttle, Bill Simmons breaks down what will and won't happen in round two.Story | Conversation | April 30, 2004
Athletes: Most impressive feat
What's the most impressive feat you see done in other sports? The athletes speak.Story | Conversation | April 30, 2004
The royal weddingHunter S. Thompson
As he celebrates marital bliss, the Good Doctor takes time to give his take on the NBA playoffs.Story | Conversation | April 30, 2003
Fan-tastic slogans for NBA 2002-'03Eric Immerman
As the 2002-03 NBA season tips off, Page 2's Eric Immerman examines the new slogans for all 29 teams.Story | Conversation | October 30, 2002


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Wenger's Russia boycott doubts
Arsenal boss Arsene Wenger doubts whether a boycott of the 2018 World Cup would be the best way to combat racism in Russia. The idea was suggested by Man City midfielder Yaya Toure after he claims he was racially abused by CSKA Moscow fans.
CSKA: 'Only Yaya Toure heard anything'
Russian club CSKA Moscow have denied that their fans racially abused Toure.
The Russian club's deputy media manager Michael Sanadze told Sky Sports News: "There is no subject to discuss. Nothing special happened.
"There was a lot of noise in the stadium. Nobody else, other than Yaya Toure, heard anything.
The only trouble that has come about was because Yaya Toure heard something."
Pellegrini: Racist chants are 'a pity for Moscow'
The Manchester City coach has said that it is "a pity" for Moscow after black player Yaya Toure was subjected to racist chants during a match in the city.
Manuel Pellegrini said:
"Well, I didn't know what happened, they just tell me there were some shouts against Yaya Toure, I think its a pity that they continue with that stupid things and I hope that would have hear (heard) the right message to finish all the things, it's a pity for Yaya, its a pity for the city I think."
The CSK Moscow coach Leonid Slutsky denied hearing any abuse, saying: "I haven't heard anything, I was watching the game".
See more: Toure puts faith in authorities to deal with racism
Toure puts faith in authorities to deal with racism
Manchester City midfielder Yaya Toure has said he has faith in the football authority Uefa to punish CSKA Moscow after some of their fans racially abused him during a Champions League match last night:
Thank you for your support! Hate or racism cannot affect me when so many people are showing me love and support on a daily basis!
I believe in football institutions, I know decision makers will take their responsibilties and show A RED CARD TO RACISM
Man City captain calls for Uefa to act on racist chants
Manchester City captain Vincent Kompany called on Uefa to act against racist chants, after Yaya Toure was racially abused by fans during a game with CSKA Moscow.
Racist chants again in Moscow today.. We've all said enough. @uefacom, @governmentrf, CSKA, all eyes are on you now.. #StopRacism
Manchester City's Toure victim of racist chanting
Manchester City's Yaya Toure was racially abused by fans from CSKA Moscow in a game this evening. The BBC reported that chants could be heard from some CSKA supporters in the Khimki Arena.
Speaking after the game he called for Uefa to do more to tackle racism from the stands. In an interview with Sky Sports News Toure said he told the referee fans were chanting racial abuse, and nothing was done about it. He said:
"Yes, of course I told him [the referee]. It was disappointing. We are always talking about no racism and they continue to do it again - it was unbelievable.
"I think Uefa has to be stronger, and hold all the clubs and all the fans that do that [responsible].
"As an African player, it is always sad when you hear something like that."