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Go Tech Yourself! @ Levine
Need help with the new Blackboard interface? Questions about Office 2013?
Levine Library will be offering two sessions to provide assistance with these resources.
August 19, 2014
Need help with the new Blackboard interface? Questions about Office 2013?
Levine Library will be offering two sessions to provide assistance with these resources.
August 19, 2014
Welcome to the 2014 fall semester! Hopefully, you had a fantastic summer and are ready to get into the swing of things. With the beginning of a new semester, we'd just like to take some time to remind you of a few of the services that the library has to offer, as well as highlight a few recent changes.
Books and More!
As always, the library wants to help out with your research and educational needs. To that end, we provide access to a wide variety of resources, both in print and online.
To find out what books or DVDs are available in the library (or in electronic format), check out the online library catalog.
If you are looking for research articles or educational online videos, have a look at our Research Databases.
Need help using either one of these resources? Don't be afraid to Ask a Librarian! Library staff are available to help in person, over the phone or online.
Study Space? We Have That!
Need a quiet place to study? All CPCC campus libraries have dedicated quite study spaces. Additionally, Central, Cato and Levine campuses have study rooms available. (Two of the study rooms at Central recently got amazing facelifts…pictures to come in a future post!)
Faculty Resources
We also offer a number of resources just for faculty. Be sure to check out our Faculty Resources page to see what we can offer you.
We hope everyone has a great semester!
August 18, 2014
Need to book a study room for yourself or a group? You can now book a room through our online reservation system. Study rooms are available at Central, Levine and Cato campuses. For more information, please click here.
June 30, 2014
The Theresa Thompson Library Scholarship was established to provide financial assistance for currently enrolled students pursuing a two-year degree at the Central Piedmont Community College (CPCC). It is made possible through library fundraising projects. The deadline for submitting an application for the scholarship is May 15, 2014.
To be eligible for the CPCC Library Scholarship, applicants must:
For more information about the scholarship program, visit http://www.cpcc.edu/library/scholarship.
March 20, 2014
Word of Mouth, CPCC Libraries' storytelling event, returns to a campus near you this month. For more information about Word of Mouth, check out the website at:
March 13, 2014
Encore is the library's innovative new online catalog. To learn more about it and the services that it offers, stop by one of our libraries the week of March 17!
March 12, 2014
January 27, 2014
Please be aware that some students are currently experiencing issues when attempting to access library databases from off-campus.
We are working to resolve the issue as quickly as possible.
January 24, 2014
Beginning December 12, CPCC Libraries will have shortened hours. From December 12 to December 18, Central Campus Library will be open from 7:30am to 5pm. It will observe abbreviated hours on December 17 from 7:30am to 12pm. All other campus libraries will be closed during this time.
From December 19, 2013 to January 1, 2014, all CPCC Libraries will be closed for the holiday season. Central Campus Library will reopen on January 2, 2014.
December 11, 2013
A new traveling exhibit at the Central Piedmont Community College Library: Central Campus focuses on major events during the Civil War. Experience the bloodiest battles in the history of the United States through the eyes of major political figures, soldiers, families and freedmen. By virtue of letters, personal accounts and images, learn how people grappled with the end of slavery, the nature of democracy and citizenship, the human toll of civil war, and the role of a president in wartime. Come to the Central Campus Library, beginning on November 5, 2013, to explore the exhibition "Civil War 150″ for yourself.
Visit http://www.cpcc.edu/library/civil-war-150 for details.
October 30, 2013


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From the FanPosts -Joel
This isn't earth-shattering news or anything, but I thought it was interesting to read what a trainer said about Poe's work ethic in Stack Magazine.
Stack is an athletic fitness and nutrition magazine found a lot in high school weight rooms. The May issue had a combine workout feature on several players. Poe received a glowing report from his trainer from a company called Athletes Performance.
"According to his trainer, Poe was one of the most dedicated, hard-working and coachable athletes he's ever worked with in his career. 'I believe the guys that go to the Combine and extremely exceed expectations are those that have perfect attendance and attentiveness,' says [his trainer]. 'When I say this--and I'm not lying--Dontari made every single session for the eight weeks. He was here, twice a day, six days a week.'"
I figured any positive report concerning the young fella's dedication and work ethic was worth passing along. See the whole feature here.

subset: commoncrawl


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August 2, 2013
Krysta Harden has been confirmed by the Senate for the job of deputy secretary of agriculture, the second-highest position with the U.S. Department of Agriculture. (Aug. 2, 2013)
Stories this photo appears in:
Harden confirmed to No. 2 USDA post
Camilla native Krysta Harden rises to the No. 2 position in the federal agriculture department.
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i read the FAQ. I do not have anything in my profile that says anything about a signature. Can anyone help me out?
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I'll take a look at your account and see if there are any issues.
I found it. I didn't realize that it was all the way at the bottom of the page. Sorry!!!
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Prayer is a very important part of our ministry at The JOY FM. We pray for your needs each weekday. Note: Prayer requests will be approved and posted within 24 hours on weekdays.
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Anonymous posted on 08/05/2013 2:34:07 PM
I need help overcoming temptations. My husband and I have been married for about 7 years and need help. I am in leadership at my church. I want to stop unhealthy habits. Thank you.
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ola posted on 08/05/2013 10:02:36 AM
Please pray that my mother Celina will regain consciousness today, that she will respond to the medical treatment and have purposeful movement. that God will breath life into her and she will breathe on her own
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Anonymous posted on 08/05/2013 12:21:45 AM
Trying to get ready for a new job and just need prayer that I accomplish my goal!
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Cris Vessell posted on 08/03/2013 9:39:30 PM
I would like to pray for my professor at a university who is going through some family issues today and would ask that his unspoken needs be lifted up and God works to ease his concerns.
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Anonymous posted on 08/03/2013 9:31:47 PM
I had volleyball tryouts August 1-2nd and I just found out I didn't make the team. I have been working so hard and the news is just devastating. I need prayers to remind myself that GOD is in control and I need to trust in Him, even when I don't know what His plans are for me!
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Rachel posted on 08/03/2013 6:39:10 PM
I have painful ovarian cysts that seem to not be going away and getting larger. Please pray that I will be heal for this. Thank you so much.
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Anonymous posted on 08/03/2013 3:34:25 PM
I need your prayers to push through to the answer that is just around the corner. God said it and He will do it, I just need your prayers to help me keep holding on... Never give up, never stop praying, never stop praising The Holy God we serve! My prayers are with all of you who are bold enough to ask for prayer, here or anywhere, for this is how we share each other's burdens. The Word says 'you have not because you ask not'. KEEP ASKING! KEEP SEEKING! KEEP KNOCKING! Thank you and GOD'S blessings on all who ask and pray.
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the frestons posted on 08/03/2013 2:42:44 PM
Please pray for our family in our many upcoming appointments for our youngest daughter BryLeigh! She was born Deaf and she will be getting a cochlear implant on Sept 26 and they do not believe that the cochlear implant will help but are doing it as a step in the process for a brain stem implant that is a study at UNC chapel hill!
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Tiffany Crawford posted on 08/03/2013 11:57:56 AM
I am asking for prayer as i go back to the doctor to see about surgery to remove the brain tumor that i have. I was diagnosed about 5 months ago. Its been a long process but i know God has been with me through it all even When my faith runs dry. Thank you 93.3 for being such a inspiration.
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Ketty louidor posted on 08/02/2013 10:06:54 PM
good health for my husband with a heart problem and me just find out I am diabetic.
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There hasn't been much news about the long-in-the-making Atlantic Avenue BID since November, when subcommittees from CB2 and CB6 voiced support for the business improvement district. However, at last week's CB2 meeting, there was word that there will be a public City Council hearing for the BID's establishment on April 28th, and the date's been confirmed on the proposed BID's website. If approved, the district would cover all properties fronting Atlantic Avenue from the BQE to 4th Avenue, as well as one block north and south on all side streets. The BID's budget would be $240,000 a year for marketing, sanitation, streetscape, and traffic and crime advocacy.
Atlantic Ave. BID Gaining Momentum [Brownstoner]
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"The BID's budget would be $240,000 a year for marketing, sanitation, streetscape, and traffic and crime advocacy."
Great, its about time someone stood up for robbers and the like.
meanwhile the heavy double-load of NY State and City Taxes that every merchant and employer on the Avenue pays goes to what? I'm sure most local merchants need an additional tax, in the form of the BID fees, like a hole in the head.
Hopefully the funds to cleaning up the Eastern end (Nevins and beyond) and getting that damn south side parking PM restriction lifted!
we all pay state and city tax, Minard.
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Welcome All! Buy HERE with CONFIDENCE.Customer SATISFACTION is our #1 GOAL. Thank You for looking and I hope you find some great BARGAIN...read more
I will be on vacation from Friday July 18th and will be back in the office on Tuesday July 29th. Any purchased item will be shipped on my return, but I will be checking in from time to time for any questions that need to be answered.


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Product Details:
Manufacturer: Monte Carlo
Mfg Part#: 5ALR56RBD
Sku: 210905382
Package Weight: 41 lbs
See more in Ceiling Fan Lighting
|MON1018: Features: -Blade Pitch: 14.-Heavy duty 188 x 25mm torque induction motor.-Precision balanced motor for wobble-free operation.-CFM: 8400.-Watts: 90.-Amps: 0.7.-RPM: 158 / 118/ 75. Includes: -Integrated light kit requires two 50 watt halogen and three 25 watt incandescent bulbs (included).-Includes wall-mount remote control with reverse and up/down light control..-10'' Downrod included. Color/Finish: -Finish: Roman Bronze with Teak Blades. Dimensions: -78'' Lead wire provided.-Dimensions: 38.72'' H x 56'' W. Collection: -Alicante Collection. Warranty: -Limited Lifetime Warranty.


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Route Guide - iPhone / Android - Partners - Forum - Photos - Deals - What's New - School of Rock
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A short, short problem that packs a punch. Start seated with a right-hand crimp in a sloping slot and your left-hand just below gastoning a good crack. The start is a but odd, but it is the logical, lowest starting position. Your feet are on the large base of the boulder; the base of the boulder is not off! Thin crimping, hard compression, and brute strength get you to the top. The problem is called Humpy Hump for a reason.
About 15ft to the right of Fat Man boulder. Located on a short boulder (10ft) with an obvious blunt prow that faces the main trail.


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Auto News
AutoGuide News Blog
The AutoGuide News Blog is your source for breaking stories from the auto industry. Delivering news immediately, the AutoGuide Blog is constantly updated with the latest information, photos and video from manufacturers, auto shows, the aftermarket and professional racing.
FENDI and Maserati have partnered to bring you the new leather and accessories Travel Kit Capsule Collection.
Designed by Silvia Venturini Fendi, the Travel Kit Capsule Collection is made using black Cuoio Romano leather that is adorned with Selleria stitching. Each item in the collection comes with numbered oval sterling silver plaque that is engraved with Maserati Trident logo. The line features a compact trolley case, a soft Boston bag, two vanity cases, a document folder, a keyholder, two bomber jackets, an oversized cashmere scarf, a baseball cap and aviator sunglasses.
This Travel Kit will be accompanying the Maserati GranCabrio Fendi on "The Whispered Grand Tour" journey, which celebrates the two companies' like minded vision regarding tradition, innovation and craftsmanship.
GALLERY: Fendi Maserati Travel Kit Collection
Maserati and luxury goods maker Fendi have teamed up to design a masterpiece of technology and craftsmanship, the Maserati GranCabrio Fendi.
The GranCabrio features a three-layered body color named Grigio Fiamma Fendi, and is a special dark grey with an iridescent golden finish on the surface. The Pergamena Fendi wood trim runs across the width of the dashboard, on the doors and on the gear shifter, while Fendi yellow can be found on the brake calipers and the embroidered yellow trident on the headrests. Fendi's double F-logo is featured stitched into the headrests, and is on the center of the 20-inch Trident design alloy wheels, with Fendi logos along the rocker panel. Fendi's most luxurious leather (from the Selleria line) can be found on the instrument cluster cover and on the floor mats. A specially crafted plaque adorns the dashboard showing the trident design with a Fendi logo and a five digit serial number.
Under the hood, the GranCabrio Fendi features a 4.7-liter V8 engine mated to an automatic transmission. Not only will the owner be cruising in style, but will have the power to back it up.
purse exotic sports car will be introduced at the Frankfurt Auto Show in September 2011.


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By WALKER SYDNEY III. , M.D. 299 pages. Charles C Thomas; , Publisher, Sprinfield, Ill.: , 1967.. Price, $11.50.
A syllabus of symptoms, signs, and laboratory findings of medical disorders that exhibit psychological or behavioral abnormalities at their outset or during their course. The material, presented in compressed abbreviated outline, covers all body systems and the diseases and dysfunctions that afflict them.
This might be a useful guide to the hurried psychiatric clinician or psychiatric resident preparing for examinations.
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In response to:
Fischer who???
king10 - exposing leftism Wrote: May 09, 2012 7:26 AM
Exactly...this is classic inside-the-beltway musings that go nowhere....but seem important to those inside the beltway.
"If Mitt Romney can be pushed around, intimidated, coerced, co-opted by a conservative radio talk show host in Middle America, then how is he going to stand up to the Chinese? How is he going to stand up to Putin?" So asked Bryan Fischer, a radio host with the American Family Association, after claiming credit for Richard Grenell's scalp.
Grenell is the openly gay former foreign policy spokesman for the Romney campaign. Before that, he worked for Ambassador John Bolton at the United Nations, easily the most revered diplomatic official among the base of the Republican Party since Jeane...


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A collection of news and information related to Shanghai (China) published by this site and its partners.
Top Shanghai (China) Articles
Displaying items 111-121
Need an Asian language interpreter, teacher or city navigator? There's an app for that
High Five wooden roller coaster to debut in China
Dreams of China
Movie Review: 'Snow Flower and the Secret Fan'
Reel China: Will it play in Peoria and Shanghai?
Review: "Dreams of Joy" by Lisa See
Shanghai stock market closes with a spooky echo of Tiananmen SquareStory | Jun 4, 2012 | 4:41 PMWhether a cosmic joke or coincidence -- or as some wags suggested, an act of God -- the Shanghai stock market index fell 64.89 points on Monday, which happened to be June 4, the 23rd anniversary of the 1989 crackdown on pro-democracy demonstrators at...
Shanghai film fest kicks off with honor for Mike MedavoyStory | Jun 17, 2012 | 4:37 AMThe Shanghai International Film Festival kicked off Saturday night by honoring a native-son turned Hollywood producer, Mike Medavoy....
On Location: HBO's 'Hemingway & Gellhorn' sets global stage in San FranciscoStory | Apr 24, 2012 | 4:33 PMIn the upcoming HBO movie "Hemingway & Gellhorn," actors Clive Owen and Nicole Kidman bring to life the passionate and stormy relationship between Hemingway and World War II correspondent Martha Gellhorn, the inspiration for his novel "...
China bars O.C. businessman from returning home, citing contract disputeStory | Jan 9, 2011 | 9:33 PMA businessman from Orange County said Chinese government officials have prohibited him from leaving China for the last four days, saying he must resolve a contract dispute with a Chinese supplier before theyâll let him return to the United States.......
Barbie's flagship store closes in ShanghaiStory | Mar 7, 2011 | 4:34 AMBarbie's giving up the keys to her dream house in Shanghai. Two years after opening it to great fanfare, Mattel Inc. shuttered Monday the company's only stand-alone store dedicated to the iconic American doll. A spokeswoman for Barbie in China......


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Central Waters Slainte Scottish Ale
"..Very nice blend of smokey and sweet malt flavors. There is a small flavor of herbal hops. The sweetness amd smoke are by far most obvious..another fine addition to an already proven line-up of brews offered by the crew at CW.."
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Summer science ideas for you and your little ones!22 July, 2014 Five Ways to Encourage Your Little Scientist1. Follow Their LeadAs most parents already know, kids... read more
Unique and Creative Ways to Announce to your Husband, Friends, and Family that you are Pregnant14 July, 2014 How To tell your partner: 1. Rent out a baby themed movie and hope that... read more
Making a Diaper Cake for Baby Showers14 July, 2014 Are you on the lookout for the perfect baby shower gift ideas that are not... read more
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Cave permits now available for selected park caves
FREE mandatory cave permits are now available to visit specific caves in El Malpais. Permits can be obtained at the Northwest New Mexico Visitor Center at I-40/Exit 85 or at the El Malpais Information Center on NM Highway 53. More »
Crews manage wildfire near Lost Woman Crater
A small wildfire near Lost Woman Crater is being managed by crews from the National Park Service and the Bureau of Land Managment. Recent heavy rains will minimize fire growth, but travelers may experience smoke on NM 53 near the continental divide.
Event Details
07/27/2013Location: El Calderon Area on NM 53 Time: 8:30 AM to 10:00 AM Fee Information: No fees Contact Name: Information Center Contact Phone Number: 505-783-4774
Learn how to use high intensity intervals to meet fitness goals and improve your health. Meet a ranger at the start time in the parking lot of the El Calderon Area (21 miles southwest of Grants on NM 53). Wear fitness attire, a hat, and sunscreen. Bring water and a snack.


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Samra, Haifa (Abou) PhD, RN-NIC; McGrath, Jacqueline M. PhD, RN, FNAP, FAAN; Wehbe, Michelle; Clapper, Jeffrey PhD
College of Nursing (Dr Samra) and College of Agriculture and Biological Sciences (Dr Clapper), South Dakota State University, Brookings; Nursing Research, Connecticut Children's Medical Center, Hartford, and School of Nursing, University of Connecticut, Storrs (Dr McGrath); and Program in Neuroscience, University of Michigan, Ann Arbor (Ms Wehbe).
Correspondence: Haifa (Abou) Samra, PhD, RN-NIC, College of Nursing, South Dakota State University, Box 2275, SNF 209, Brookings, SD 57007 (firstname.lastname@example.com).
The authors declare no conflict of interest.
Adverse experiences early in life have the potential to disrupt normal brain development and create stress response channels in preterm infants that are different from those observed in term infants. Animal models show that epigenetic modifications mediate the effects of maternal separation and environmental stress on susceptibility to disease and psychobehavioral problems later in life. Epigenetic research has the potential to lead to the identification of biological markers, gene expression profiles, and profile changes that occur overtime in response to early-life experiences. Combined with knowledge gained through the use of advanced technologies, epigenetic studies have the promise to refine our understanding about how the brain matures and functions from multiple perspectives including the effect of the environment on brain growth and maturation. Such an understanding will pave the way for care practices that will allow the premature brain to develop to its full capacity and will lead to the best possible outcomes. Neonatal epigenetic research is emerging and rapidly advancing. As scientists overcome biological, technical, and cost-related challenges, such research has a great potential in determining key environmental factors that affect the preterm genome, allowing for targeted interventions. The purpose of this article is to explore existing literature related to epigenetic mechanisms that potentially mediate the effects of the environment on preterm infant brain development.
Epigenetics is a field of expanding research and growing relevance and importance in today's healthcare world. For neonatal nurses in particular, it is important to understand how key environmental factors contribute to epigenetic changes in neurons and neuronal networks and how those changes affect long-term outcomes and susceptibility to disease. As the body of work related to epigenetics continues to grow, so does the realization that early-life experiences have significant effects on brain maturation, development, and long-term outcomes.
With increasing survival rates, the focus of neonatal care during the last 2 decades has shifted from a rescue model to a paradigm centered on improving quality of care and reducing morbidity.1 Family-centered developmental care interventions aimed at reducing stress, supporting self-regulation, and promoting positive experiences for the infant as well as the family have become an essential aspect of routine care giving in the neonatal period.2 There is no one universal definition of family-centered developmental care: it encompasses a wide range of practices from swaddling to skin-to-skin holding (kangaroo care) and infant massage to the implementation of the Newborn Individualized Developmental Care and Assessment Program to the bundled implementation of those strategies within the family unit.2–4 Despite improvements in care practices and the perceived benefits of developmental care interventions, neurodevelopmental outcomes in preterm infants remain of great concern. The long-term effects of developmental care on brain development and the mechanisms that mediate its influence on neuronal responsiveness and changes in neuronal cell biology in response to stress remain unclear. The identification and characterization of key environmental factors that affect neuronal and hormonal networks in preterm infants through the alteration of genetic character may provide insights into the origins of many behavioral and developmental issues that may arise during the neonatal period and develop later in life. Focusing on the biological mechanisms of developmental care will allow for increasingly targeted interventions and will maximize the benefits gained from neonatal care practices.
In eukaryotic organisms, the nucleus of each individual cell contains large, linear chromosomes. These chromosomes (see Table 1 for definitions throughout this section) carry the genetic blueprints for life in the form of DNA. DNA can be replicated for cell division or transcribed into messenger RNA (mRNA), which in turn is translated into amino acid sequences during protein synthesis. These processes form the basis for both the generation and development of life. Differences among individuals can often be attributed to the presence or absence of different genes, as determined by the specific sequence of base pairs within the genome. However, not all variations among individuals can be attributed to differences in DNA sequence and genotype; many phenotypic differences are a result of changes that occur above the level of nucleotides and genes—that is, epigenetic changes.
Epigenetics is defined as the study of those cellular processes that determine the function of genes.5 Epigenetic changes typically occur at the molecular level and involve DNA or its supporting proteins. Such activity leads to alterations in activation or transcription of certain genes, while the structure and sequence of DNA remain unchanged. DNA methylation and histone changes are the most common epigenetic mechanisms. DNA methylation (addition of a methyl group to the DNA molecule), gene expression regulation (phenotype), and changes in the chromatin structure of the gene are examples of molecular changes that directly involve DNA. Changes to supporting proteins often involve histones and altered functioning of eukaryotic proteins that have roles in the packaging, ordering, and storage of the DNA. Methylation or demethylation of histones can turn on, turn off, amplify, or silence gene expression. Gene expression involves the transcription of DNA to mRNA and the translation of mRNA into protein. Protein synthesis, a continuous process, is essential for enzymatic activity and metabolism. DNA methylation patterns are inherited during cell division, and epigenetic patterns determine the different types of cells in the body during cell differentiation. Any interruptions or alterations in the enzymes that regulate DNA methylation or histone modification can lead to epigenetic pattern changes. Epigenetics can explain why identical twins can exhibit dramatically different phenotypes later in life.6,7 Table 2 provides links to illustrations and further information on epigenetics.
The effect of epigenetics on the development and function of neuronal networks starts at conception and continues into infancy and early childhood.8 Infants born prematurely are most often cared for in less than ideal physical and pyschosocial environments. Maternal separation and adverse experiences in children with disadvantaged backgrounds have been shown to cause early adaptations in gene expression, lead to altered protein expression across the life span, and therefore increase the risk for chronic disease and mental health problems.9–16 On the basis of these findings, it can be assumed that similar adaptations can potentially occur in preterm infants, given that they encounter multiple early adverse experiences coupled with long periods of maternal separation while in the newborn intensive care unit (NICU). Epigenetic information may prove to be extremely relevant to care giving provided in the NICU.
Animal models have shown that sensory stimulation plays an important role in neuron function and influence neuron differentiation and neuronal pathway development through epigenetic modifications.11–13 Infants in the NICU are often isolated from maternal care for long periods of time and are exposed to noxious sensory stimuli such as noise, light, pain, medically related touch, and medications that raise concern about environmental programing. In addition, nutritional management is not always optimal in the neonatal period even though it is essential for optimal brain development. Although it has been shown that optimal nutrition, developmental care, and maternal care early in life have a positive effect on morbidity and mortality in preterm infants, it is less known whether those effects are mediated through specific epigenetic changes.3,15,16 Optimal brain development is a function of 3 variables: genes, appropriately supportive environment, and nutrition, and how these 3 variables interact together. The purpose of this article was to explore existing literature relevant to possible epigenetic mechanisms mediating the effects of nutrition and environment on brain maturation and development.
In collaboration with a medical librarian who is experienced in searching computerized bibliographic databases, the authors conducted a cross-database search in EBSCO, using Expanders for search within the full text of the articles published within the last 10 years with search modes as described in Table 3. Inclusion criteria for this review included research and review articles on epigenetic mechanisms in preterm infants, environmental programing, and postnatal programing and brain development. For the purposes of this review, care environments were defined as the physical, chemical, and nutritional contexts and practices that preterm infants generally experience during the immediate perinatal period. This included maternal care and sensory stimulation such as pain and noxious stimuli (ie, noise and light).
The search yielded 12 articles. The articles were retrieved, examined for relevance, and searched for any previous reviews including cross-references, abstracts, conference, symposia proceedings, and dissertations. A search of the Biological Abstracts Previews was also conducted. An additional 9 articles that could potentially have some relevance to the topic were identified for inclusion in the review.
Of the 21 articles, only 1 article was a research study that met the search criteria. Three other articles met the criteria and were general review articles. Only in 1 of 3 review articles, the authors provided a description of their search strategy and study inclusion criteria. This review, which was authored by Lui et al,3 examined care practices that support neurodevelopment in the NICU. The remaining 2 reviews by Wiedmeier et al15 and Gudsnuk and Champagne6 did not follow any specific timeframe or guidelines and recommendations for conducting integrative reviews.
The second review by Wiedmeier et al15 examined animal studies involving diet modifications leading to postnatal programing and development of metabolic disease later in life. Mechanisms implicated in such modifications were explored and included alteration in the hypothalamic-pituitary-adrenal (HPA) axis pathways. The third review by Gudsnuk and Champagne6 was a summary of findings on epigenetic mechanisms contributing to long-term impact of early-life adverse experiences on behavioral and psychosocial well-being. There was a significant overlap among the review articles with the same animal models being discussed and cited in more than 1 article. The research study by Guzzette et al16 examined effects of massage on brain development and on maturation of visual functioning. Cellular and molecular mechanisms involved in visual maturation and development were explored. The following section includes a synthesis and discussion of findings presented in the 4 articles that met the review criteria.
Lui et al3 provided a detailed review of brain development and how various exogenous and endogenous stimuli influence brain maturation with the focus on the role of sleep in brain development. The purpose of their study was to review current evidence supporting care practices that are believed to promote optimal brain development in newborns. The review was based on the work of the exploratory group formed by a 5-member hospital of the Vermont Oxford Network–sponsored Neonatal Intensive Care 2005. The authors provided an overview of and made recommendations on existing care practices most commonly used in the NICU including skin-to-skin holding kangaroo care, tactile stimulation, massage, nutritive suck, swaddling, and pharmacological therapies used for analgesia and sedation. The authors proposed a bundled approach to family-centered developmental care.
When an infant is born prematurely, rapid brain growth that should have taken place in utero occurs postnataly.17 Beginning as early as 24 to 28 weeks' gestation and extending through the first 3 years of life, the human brain goes through extensive modification of its neuronal connections. This period of rapid synaptogenesis followed by synaptic pruning and restructuring is considered to be "critical" for optimal brain development.18–20 Neurogenesis and synaptogenesis are 2 intricate processes that underlie brain development and that are regulated by endogenous and exogenous stimuli.3 Endogenous stimulation processes are defined as those processes that are independent of factors external to the brain and are mediated by the presence of neurotransmitters such as acetylcholine and glutamate. Neurotransmitters connect brain regions together through synapses and mediate brain plasticity.18–21
Exogenous processes are activity-dependent and occur in response to sensory input. Endogenous processes coupled with brain plasticity, the ability of the brain to rewire and adapt, prepare the brain for the integration and interpretation of sensory input. Sensory input is essential for normal brain development, and deprivation of such stimulation during critical periods of growth will result in alterations in neuronal development.22 Sensory systems are believed to develop in a sequential (not simultaneous) manner. Therefore, the timing, type, and level of sensory stimuli the brain is exposed to play an important role in normal neuronal development. Excessive and early introduction of one type of stimulus may lead to gains in the sensory system that is related to that stimulus, but to a loss or alteration in the sensory systems that are related to other stimuli.23–26 Exposure to environmental stimuli can have a significant effect on how the brain wires, fires, and connects, especially if the brain is in a vulnerable and premature state. Signals from external stressors are converted into biochemical responses triggered by a cascade of events that take place in the subcortical structures and neurotransmitter systems in the brain and that are initiated by the release of the corticotropin-releasing hormone.10 This is the pathway that investigators normally think of being activated with stress. However, there are many others that are activated during stress, which are beyond the scope of this article.
The review by Wiedmeier et al15 provided a summary of animal studies involving models with dietary manipulation during the neonatal period. In addition, the review discussed postnatal growth, challenges in attaining adequate nutrition, and recent dietary advances and how those advances contribute to postnatal programing in infants born prematurely. The authors supported the assumption that epigenetic modifications mediate the influence of diet on early programing, which, in turn, primes the neonate for later metabolic and health problems.
This review discussed published evidence from animal models, suggesting linkages between epigenetic modifications involving abnormal adipose tissue lipogenic gene expression, enlarged adipocytes, and adulthood metabolic disease. Animal models also show that high-fat diets in animals who suffered intrauterine growth restriction lead to accelerated growth and high levels of circulating leptin (an adipose-derived protein hormone proven to play an important role in metabolism), energy regulation and expenditure, and appetite. Animal models show that overfeeding rats in the immediate neonatal period lead to elevated levels of glucocorticoid receptor (GR) mRNA and 11β hydroxysteroid dehydrogenase type 1 in the visceral adipose tissue. Alterations in the HPA axis lead to alterations in the ability of the rat pup to regulate food intake and energy expenditure. Therefore, it is assumed that overfeeding in the immediate postnatal period can alter the function of HPA axis and lead to early obesity.27–29
Rat models also provide insights on epigenetic modifications associated with tube feedings, which is a common practice in preterm neonates. Gastrostomy feedings of high-protein diet in rats who were separated from their mothers have been shown to lead to short-term weight gain, insulin resistance, and modified expression of glucose transporter protein 4 and glucose transporter protein 2, which are 2 proteins encoded by the glucose transporter protein 4 and SLC2A2 genes, respectively. Glucose transporter protein 4 is an insulin-regulated glucose transporter mainly found in skeletal muscle and fat cells. Glucose transporter protein 4 facilitates the transportation of glucose across cell membranes. Rats who received high-carbohydrate diets through tube feedings had increased obesity, hexokinase activity, and increased insulin synthesis with increased pancreatic islets later in life. How these findings are relevant to how human preterm infants are fed in the NICU is unknown. Yet, they are something to consider in future research exploring factors for potential long-term outcomes for preterm infants.27–30
Adequate nutrition is important for optimal brain function. Despite advances in formula compositions and availability of formula fortifiers, provision of adequate protein and energy in preterm infants remains a great challenge. Meeting nutritional requirements for adequate growth and neurodevelopment that parallel those of a gestation equivalent fetus in utero is complex and requires intricate coordination between nutrition and endogenous processes, such as growth hormone synthesis and secretion. Oftentimes, nutritional goals cannot be achieved in preterm infants because of a mismatch between their nutritional needs and the immaturity of their systems and physiology. High-protein diets and the use of specialized formula have been associated with improved neurodevelopment and growth. However, those diets are believed to present an increased risk for obesity later in life. There is also growing concerns about the contribution of rapid rate of growth early in life to the development of adult disease including metabolic disease, type II diabetes, cardiovascular disease, and visceral adiposity. The mechanisms by which early diet leads to adulthood disease in preterm infants are not clear. Animal models point to the possibility of long-term epigenetic changes.29,30
Current evidence on the relationship between diet in the immediate postnatal period and programing and how epigenetic modification mediates programing comes from animal models. To date there is limited evidence involving human studies. Data come predominantly from retrospective epidemiologic studies and findings from those studies are consistent with animal findings.14,31–33
This review yielded 2 articles involving epigenetic modifications, maternal care, and brain development in preterm infants. A study by Guzzette et al16 examined how epigenetic modifications mediate the effect of tactile stimulation and maternal care on the maturation of visual acuity. The investigators concurrently confirmed their findings with human infants to animal models, using rat pups. Ten medically stable infants born between 30 and 33 weeks' gestation received massage therapy, which was delivered over 2 blocks of time, 5 days each separated by a 2-day break. Infants were matched with 10 controls for age, gender, and birth weight. Massage therapy sessions started on day 10 after birth and consisted of 10-minute tactile stimulation followed by kinesthetic stimulation. Fine-tuned German music was played in the background during massage therapy. Several outcome measures were obtained pre- and postmassage and included (1) anthropometric measures of length, weight, and head circumference; (2) electrophysiological assessment including electroencephalograms (EEGs) and flash visual evoked potential to measure visual system maturation and brain auditory-evoked potentials; (3) serum levels of insulin-like growth factor (IGF), IGF binding protein 3, glucose, insulin, cortisol, and thyroid hormones; and (4) behavioral acuity was tested at 3, 7, 9, and 12 months corrected age by the same practitioner using an acuity card testing procedure.
Testing in infants was paralleled with testing in 3 groups of rat pups. One group was separated from the mother after birth and received tactile stimulation. Another group was separated from the mother but received no tactile stimulation. A third group was kept with the mother undisturbed and served as a control group. It was found that massage therapy has positive behavioral and electrophysiological outcomes. Accelerated visual maturity was observed prior to 7 months of age in infants who received massage therapy sessions. Similar observations were made in rats.
Higher levels of IGF-I, which is presumed to have a protective effect against retinopathy of prematurity, were found, and a reduction in cortisol levels was observed in massaged infants compared with their control counterparts. Rat pups who received massage therapy were found to have increased IGF-I brain levels in both the visual and auditory cortices. Electroencephalographic tracing showed brain maturation at all electrodes in the massaged rats. Injecting an IGF-I antagonist centrally in the rat pups resulted in blocking the effects of massage on IGF levels in rat pups, indicating that IGF-I plays a role in mediating the effects of massage therapy on brain development.
Evidence from animal models shows that maternal care (licking and grooming) has a significant impact on the neurobiology of brain development. Gudsnuk and Champagne6 provided a summary on animal research involving epigenetic effects of early-life experiences on behavioral outcomes. The review provides valuable insights from animal models on how maternal care affects brain development. Effects are believed to be mediated by molecular changes involving gene transcription crucial for the synthesis and release of specific hormones and enzymes.
Animal models show that maternal care plays an important role in GR expression and HPA activity as well as attachment between the mother and her infant.34 Rat pups who receive good maternal care through licking and grooming lose their GR methylation and as a result develop more GRs in the hippocampus. A higher number of GRs allow for better regulation of glucocorticoid hormones, which play an important role in the capacity of the pup to respond to stress. Alterations in glucocorticoids receptors are believed to persist later in life. Grooming and licking increase GR gene transcription in the hippocampus, which in turn protects rat pups from glucocorticoid hypersecretion.35
In addition to its effect on the HPA activity, animal models also show that grooming and licking by the mother have an effect on estrogen, growth hormone, and ornithine decarboxylase, a regulator of cell proliferation and differentiation. Female pups who were subjected to low levels of licking and grooming were found to have decreased transcription of estrogen receptor alpha (ERα) in the medial preoptic area of the hypothalamus. Estrogen's neuroprotective effect occurs through the 2 preceptors ERα and ERβ. Both receptors are present in the neocortex. Westberry and colleagues36 found that ERα protein expression reflects changes in mRNA expression, and ERβ gene expression is regulated by DNA methylation following middle cerebral artery occlusion in rats. Gender was found to have a differential effect on DNA methylation with males having higher levels of DNA methylation. Changes at the molecular level in the neuronal system affect synthesis and secretion of various hormones that control cell differentiation, behavior, and cognitive functioning. Rat pups deprived of maternal care showed altered circadian rhythms, impaired tissue growth, and learning and memory deficits.
No doubt, evidence from animal models has expanded our knowledge and enhanced our understanding on how exogenous stimuli influence brain chemistry, maturation, wiring, pruning, and function. Currently, there is a paucity of data on epigenetic modifications in preterm infants. Lester et al37 and Pickler et al38 have each developed conceptual models to infer how these variables might be related to family-centered developmental care and experiences in the NICU. Results of the efficacy of these conceptual models are currently unavailable in the literature. More research is needed to understand these variables and their moderating or mediating relationships to each other. Furthermore, findings from such research with the preterm infant would support the development of targeted interventions to best support positive short- and long-term outcomes. Inferences can be made that long-term epigenetic adaptations involving environmentally sensitive pathways similar to those observed in animals occur in premature infants, as many features of mammalian development tend to be similar. Despite significant changes to neonatal care practices and care environments, there remains a great concern about the level of maternal separation and noxious stimuli that a preterm infant experiences early in life. Brain development is dynamic with constant interaction between the brain and the environment. There are multiple pathways implicated in the neurodevelopment of preterm infants. The level, quality, and type of sensory stimulation that the brain receives play a significant role in how the brain wires, fires, and relays information from one region to another. Preterm infants are vulnerable for programed changes if their care environments are less than optimal. Epigenetic modifications occur to increase chances of survival during stressful periods of development. Survival may come at a high long-term cost; in addition, modifications could be transferred from one generation to another. Recent studies in preterm children revealed increasing rates of mild cognitive, sensory, language, attention and learning deficits, behavioral and motor problems, and low developmental scores.39,40 Other than early gestation, there is no direct evidence to link such deficits to early-life experiences or to provide insights on the contribution of adverse early-life experiences to such outcomes.
Animal models are the basis for research in humans and at this time provide overwhelming evidence linking adverse experiences early in life to interruptions in brain maturation, which could have long-lasting effects. Even though they are built on sound scientific principles, there are still detailed differences in brain structure and neurobiology between animal and humans. Epigenetic research in humans is emerging and rapidly advancing. As scientists overcome biological, technical, and cost-related challenges, such research has a great potential in determining key environmental factors that affect the preterm genome, allowing for targeted interventions. Epigenetic research has the potential to lead to the identification of biological markers, gene expression profiles, and profile changes that occur overtime in response to early-life experiences. Combined with knowledge gained through the use of advanced technologies, epigenetic studies have the promise to refine our understanding on how the preterm brain matures and functions from multiple perspectives. Such understanding will pave the way for care practices that will allow the preterm brain to develop to its full capacity and will lead to the best possible outcome. Meanwhile, several care strategies have been identified, which are believed to protect and support brain development. A previous publication by the authors provided a discussion of such strategies.41
Conversion of stress signals into biochemical responses within cells triggers a cascade of events, the nature of which depends on how the signals are perceived by the cell. It is speculated that early-life experiences alter the stress response and create stress response channels in preterm infants different from those observed in term infants that disrupt normal brain growth and development. Healthcare providers must be cognizant of the implications that environmental stress has for brain development and must use every opportunity and care encounter to influence the brain plasticity in positive ways.
developmental care; environment; epigenetics; genetics; neonatal intensive care; nutrition; preterm infants
© 2012 National Association of Neonatal Nurses
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text:
MatRu Go
I want to transfer from east to west EU server, but my name is taken on west. Will I still be able to transfer?
Senior Member
Bring back the lolipopy skin
Junior Member
what if the summoner is lvl 12 and has not played since last summer
uhm Hippalus I Wanted to ask, I just bought a name change like 3 days ago, and thanks to the awesome riot team I managed to swap names with an old account of mine that I used to save the name I wanted for a while. There's absolutely no way I can receive half of my RP back right? I know it's a stretch and given the conditions I put you guys through it'd be a miracle if I could, but since you said the sale would've began this week I just wanted to ask O.o
Also O.o I thought my name would change in the forums too O.o is this some kind of bug? my name now should be "Hige" O.o
Super Yaoi Time
I just got a name change 2 days ago....!!! Just my luck.... Is there any way I could get a refund and participate in the sale? ;4; (This always happens to me when I buy a skin full price, and it goes on sale a week or two later... )
Steam Store
legendary skins on sale would be legendary
Thlng One
Also will there not be a normal sale this Friday just like every other Friday, whats so hard to just add a few more skins and champs to the mix and call it the Black Friday deals? I am just confused to why no one in the company thought of this before today. I am sure people knew what this Friday was.
© 2013 Riot Games, Inc. All rights reserved. Riot Games, League of Legends and PvP.net are trademarks, services marks, or registered trademarks of Riot Games, Inc.


text:
$755—$1,252 1—3 bed 2040 Ashley River Road, CHARLESTON SC, 29407
from $755 1—3 bed
2040 Ashley River Road, Charleston, 29407
Commute to Downtown Charleston
from $755
1—3 bed
The rent at Woodbridge Apartments ranges from $824 for a one bedroom to a $1,252 three bedroom. Apartments in this building are about 14% less expensive than the Charleston average.
This apartment is in Charleston.
Woodbridge Apartments has a Walk Score of 52 out of 100. This location is Somewhat Walkable so some errands can be accomplished on foot.
Nearby schools include West Ashley Middle School, Ashley River Creative Arts Elementary School and Palmetto Academy Inc.
The closest grocery stores are Naaucc PA Research Center, In Good Taste and Food Lion of Charleston.
Nearby coffee shops include Foodies Cafe & Catering and Sunflower Cafe. Nearby restaurants include Bear E Patch Cafe, Charleston Crab Shacks and Delicious Delights Workshop.
Woodbridge Apartments is near Saint Andrews Parks and Recreation, Saint Andrews Parks and Recreation and Lowdes Grove Plantation.
Steven Koehl
May 31, 2014
Management was a bit off but when I got a deployment they let me out of my lease with little hassle
A Google User
Oct 29, 2011
Do not move in this place!!!! We moved in to an apartment infested with bed bugs!!! And let's not even go to the manager ( PEGGY)....WORSt person to deal with...
A Google User
Nov 23, 2011
Please keep driving past this place
Kendra Mesmer
Jul 01, 2011
A Google User
Nov 27, 2010
Owner/manager tools | Report bad listing | From ApartmentFinder.com
Charleston, South Carolina, 29407
Some errands can be accomplished on foot.
Explore how far you can travel by car, bus, bike and foot from Woodbridge Apartments.
View all Charleston apartments on a map.


text:
< Back to Program Details
Your scholarship search found 1 results for program "Mechanical Engineering Technology - Industrial Design" in "Seneca College of Applied Arts and Technology".
|School of Study
|Field of Study
|C.N. Scholarship
|Seneca College of Applied Arts and Technology
|Civil Engineering Technology/Technician; Electrical, Electronic and Comm. Engin. Tech./Technician; Mechanical Engineering/Mechanical Technology/Technician
|Oct 12, 2014
Canada's Luckiest Student 3
Amount: $75,000
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text:
Photos and Description of this 3 bedroom holiday farmhouse in Middletown - Paradise
3 Bedrooms, 3 Baths, (Sleeps 6)
Paradise Avenue is aptly named & appears to be the preferred strolling lane for all. Our property is in close walking distance to Sachuest Beach, 2nd Beach to the locals, 3/4 of a mile and you are there! Easy access to surfing, paddle boarding, boogie boarding, kayaking, sailing............ Across the street you can walk the trails in Paradise Valley Park or 'The Windmill Park' Our home is a very comfortable farmhouse that has additions added to expand the living areas. There are three bedrooms on the second floor, one suite with private bath and a shared second bath. An additional bath with shower is on the first level outside the three season sunroom. Neutral colors, hardwood, brick and ceramic flooring
The well equipped, sun filled kitchen has double ovens, cook top, compactor, disposal, dishwasher, microwave, French door refrigerator and all the gadgets for preparing your favorite meals. Washer & Dryer, wifi, cable television, cotton linens and beach towels are provided to our guests.
Enjoy the rear courtyard patio for morning tea/coffee and cookouts!
You will be relaxing quietly in the country but downtown Newport is only a 2 mile drive. Historic mansions, The Tennis Hall of Fame, Tall Ship Festival, Art Museum's, Library, Theater's and fantastic restaurants are minutes away!
- Suitability:
- non smoking only
Jackie Cousens /Owner is a licensed Real Estate Salesperson in the State of Rhode Island
A peaceful country setting close to the pristine beaches of Middletown but only minutes away from the world class restaurants, mansions & attractions of historic Newport.
Convenience, privacy, location, location, location!


text:
ATLANTA – Women from 26 companies graduated from the Pathbuilders Percepta® program on March 4, 2014 in Atlanta. Percepta is a six-month program that focuses on developing high-performing professional women and preparing them for leadership positions within their companies. Percepta utilizes a unique methodology combining educational workshops, group mentoring and peer networking.
"Most of these women have mastered the technical aspects of their jobs and are ready to have greater impact, and for that they need a broader understanding of the inner-workings of their organizations and what it takes to be successful," says Helene Lollis, president of Pathbuilders, Inc. "Our impact on organizations is how we are transforming the very people that will take the business to the next level."
Percepta focuses
Author:Kristen Leye-mailWeb: www.fulltiltconsulting.comPhone: 4043887047


text:
Jamie Scarano
S3-G Effective Strategies to Foster a Culture of Inclusion through Executive and Employee Engagement
About Jamie Scarano
Jamie L. Scarano is the Director of Integrated Inclusion for the Center for Inclusion at UPMC, a $10 billion, 20-hospital global health system and health plan based in Pittsburgh, PA. With a 55,000 employee base, she is responsible for ensuring that inclusion is integrated into the day-to-day business practices and overall strategic initiatives. She meets with key stakeholders to strategize on how inclusion can transition from being a bolt-on approach to a built-in strategy. Jamie has been dedicated to assisting her internal network with support as they focus on a culture of inclusion through UPMC's Dignity & Respect Campaign, a workplace and community initiative designed to promote inclusive behaviors.


text:
It's 10 p.m. on a Friday night. Your stomach emits a low rumble, but you're elbow-deep in Bioshock Infinite and you'd rather not leave the warm imprint you've carved out on the couch. Your Seamless-equipped iPhone is charging in another room. Too far. The fridge? Good luck whipping something up with Sriracha and baking soda. You wonder: If only there were a way to order pizza through my TV. Behold:
The official Pizza Hut app for Xbox Live. The international gatekeeper of weird pies is partnering with Microsoft's Xbox team to develop a first-of-its kind app that lets you customize a pizza onscreen using the 360's controller, Kinect motions, or voice commands. Your cheesy design gets delivered to your doorstep soon thereafter.
The app, which spokespeople from Pizza Hut and Xbox say has been a long time coming, was born out of a "mutual conversation," reports Polygon. Demographic: Nailed. Here's Xbox's Larry Hryb:
"We're always looking at ways to give our audience more of what they're interested in," he said. "If you look at our audience, they love pizza. I mean, who doesn't? It has international appeal, and Pizza Hut is a recognized brand that matches up well with the Xbox brand." [Polygon]
Imagine: A Jedi-like wave of your hand. Pepperoni. No wait. Another wave. Sausage. Or, perhaps you'd rather bark a throaty voice command: Breadsticks. The official Pizza Hut app will go live April 23, and Xbox users will get 15 percent off their first purchase through May 6.
The future is here, folks. And it's glorious.
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The wait is over! Download the BeerAdvocate app on iTunes or Google Play now.
Get 12 issues / year of BeerAdvocate magazine for only $9.99!
Granite City Food & Brewery
Ratings: 11 | Reviews: 8 | Display Reviews Only:
Reviews by JamesMN:
3.68/5 rDev +5.1%
A real big restaurant that I've been to several times. While initially it was one of my favorite places to grab a craft beer on-tap (even have a growler to fill there), I've become quite bored with their beer selection. Most of it is pretty bland for a beer enthusiast like myself. Although, I'd recommend getting a Mug Club card just for the large, and less expensive, glass of beer. Would really love to see them make an Imperial IPA or have a more rotating micro-brew selection.
The food is very good and the service isn't bad at all. But the food can get a tad pricey for what it is. Also beware that this place is always packed full on weekend nights. Be sure to call ahead to get seated quickly when you arrive.
If you've never been to Granite City before then get their flight of beers and let that decide if it's worth returning.
08-26-2012 06:13:41 | More by JamesMN
More User Reviews:
3.5/5 rDev 0%
07-12-2014 16:04:28 | More by HoppyHopperton
3.25/5 rDev -7.1%
06-01-2014 18:18:06 | More by SlightlyGrey
3.5/5 rDev 0%
03-25-2014 14:25:09 | More by DaveMiller
2.4/5 rDev -31.4%
Stopped her for dinner on a Sunday evening. The place was realtivley empty. The deocr and atmosphere was basic but tasteful and really clean.
The beer was a tastless and was a step above medicore homebrew.
Service was non existant. The place was empty yet service was still slow at best.
The beer choices limited to five house made brews all of which were bland and uninspired.
The food was decent and came out rather quickly but a bit pricey. I would go back for the food but not for the beer.
09-21-2009 17:06:25 | More by mymrnngjckt
3.53/5 rDev +0.9%
As brew pubs go, this one leaves a bit to be desired. However, for a good value and very drinkable beer, it's top notch.
The atmosphere is about the same as you might expect at any chain restaurant. It's very clean and well lit, with a professional and uniformed wait staff. You'll get no surprises, it's as steady as a Holiday Inn.
The quality of the beer is somewhat less than average, when compared to the typical brew pub. However, it's far above the fare at your typical neighborhood hangout. This is the ideal pub for introducing macro-swill drinkers to something much better.
The service is quite good and the wait staff is very attentive (at this location. I've been to others that are not so much.)
The selection of beer is limited to 4 regular brews: Dry Irish Stout, Bock, IPA, and a pale lager that is WAY better than the usual macro brew. There is usually one seasonal on tap, as well. They also stock a few bottled beers.
The food is very good.
Granite City's real claim to fame is the Mug Club. When you buy in (cheap), you get to attend 6 seasonal tapping parties, with free dinner and door prizes, and you get the 25oz taps for a buck less than the cost of non-member pints.
05-24-2009 02:24:56 | More by Trigcove
3.75/5 rDev +7.1%
Nice and cozy atmosphere. Dimly lit which makes the place comfortable and somewhat private feeling. Large bar and dining areas. Typical restaraunt service. Nice wait staff. Friendly and helpful. They have about five of their brews on hand. Decent beers, nothing great. Food here is really good. Pretty large menu and prices are fair. My wife enjoys their beer and food as well. This is about as good as it gets for a brewpub/restaraunt in the suburbs. Overall, a good place for a dining/beer experience.
02-25-2009 01:44:45 | More by jera1350
3.83/5 rDev +9.4%
I went here on a recommendation from one of my friends, and I would say I was not disappointed. It has a relaxed atmosphere with lots of space. There are tables, booths and a bar to sit at where you can enjoy your drink. The service is pretty good sometimes a bit slow though. Granite City does not have the largest selection but they have some pretty good beers, with the mug club or an AHA membership you can get a 25oz mug for the normal price. I think the food there is wonderful; I have enjoyed everything I have tired there and would recommend trying new things. Over all a nice place to get some great food and a good brew.
12-09-2008 03:26:21 | More by br3wmeister
3.75/5 rDev +7.1%
Attended for lunch. I've attended this place previously under another name and ownership. The stone atmosphere is attractive, but also has a cool to cold presence (as well as cold temperature - which isn't always nice in MN in winter - or in this case a spring snowstorm). Nonetheless, it's open and fairly spacious. Bar is small. Menu is fairly broad and my food was good. Five beers available (under their patented - I believe - system for brewing). Bit of delay in service, for unknown reasons at a not particularly busy time, but attentive enough once given. I didn't ask much about the beer I ordered, but the info given was accurate. Prices seem a touch high, or maybe I just don't go out enough or am cheap, buy it wasn't ridiculous.
Overall I enjoyed the meal and I would attend again.
Thanks for lunch, Stephen.
04-01-2008 01:03:32 | More by garymuchow
3.83/5 rDev +9.4%
I went here based on the reccomendation that they have great food. And I found out just that! The food here was very good and good service to match. The beer...well the beer was moderate. The styles and offerings were fairly standards for chain brewpubs and I was not overly impressed.
I think that if they focused on more unique styles of beer to match their food. This place would be a wonderful joint to grab a pint and plate of food. The atmosphere was nice though and I was able to watch the Twins game.
02-17-2008 22:38:12 | More by ryantupy
Granite City Food & Brewery in Eagan, MN
85 out of 100 based on 11 ratings.


text:
Mark Moya, a frequent traveler in the San Jacinto on foot and mountain bike, sent a beautiful shot of a gnarled, dead tree he photographed with his telephone during a hike a Devil's Slide Trail above Idllywild. Eric Galletta also captured a very nice image with his phone in the Idyllwild woods.
CELLPHONE ART GALLERY: Idyllwild woods, Menifee lake
OCEANSIDE: Renowned Cellphone Artist Missy Churchill captures sunset
Acclaimed Cellphone Artist Missy Churchill was in Oceanside this week. It clearly of was the right place to capture a beautiful sunset at the end of a long day of sunlight around the Summer Solstice. Her fine image is the latest exhibit in the Cellphone Art Gallery on my blog. Churchill, who lives in Idyllwild,… [Read More]
CELLPHONE ART GALLERY: Vacations produce smartphone creations
When Hemetians on vacation are confronted with stunning views, they know just what to do. They create phone art. Steve Maldonado of Phil's Automotive in Hemet flew out to Lake Havasu with Mike Berry of Canyon RV to celebrate a family Father's Day weekend. They were greeted by a stunning sunset just before landing at… [Read More]
CELLPHONE ART GALLERY: Snake's lizard dinner on exhibit
Chama Kearns-Cliff of Hemet titled her latest exhibit in the Cellphone Art Gallery with a title that says it all: "Black racer eating HUGE alligator lizard." Yum. When she saw the snake snacking in her front yard, she reacted like a true Cellphone Artist. She went to work with her iPhone to create the latest… [Read More]
CELLPHONE ART GALLERY: Amelia Durham's iPhone photo tips
Amelia Durham, who takes pet and people portraits professionally through her Banyan Photography, sent me an iPhone photo of a water drop-decorated rose to post in my Cellphone Art Gallery. It's quite a nice shot that I was surprised to learn simply was taken in the right light conditions with a standard iPhone. She didn't… [Read More]
HEMET: Sheep model for bike commuter's phone
Patrick Scott keeps his eyes open and his camera ready in case he pedals upon an opportunity to create a beautiful image during his bicycle commutes between Diamond Valley and west Hemet. Recently sheep caused him to stop during a ride. They proved to be apt models for his latest exhibit in the Cellphone Art… [Read More]
CELLPHONE ART GALLERY: Shots from North Dakota
Hemet ex-patriot Jackie Owen, who was a revered teacher with the Hemet Unified School District, remains creative in her new home in Valley Center, North Dakota. Here is proof that there is beauty in North Dakota. Photos of the sky taken during a walk near her home are among the latest posts in the Cellphone Art… [Read More]


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Did you know the Chinese concept of yin-yang can be used to improve composition in art and design? Our goal as artists is to lead the viewer's eye into and around the painting while keeping interest in the focal point. Using the design aspects of yin-yang can help. Natural dualities such as male and female, light and dark, high and low, hot and cold, water and fire, and so on, are thought of as physical manifestations of the yin-yang … [Read more...]
A Beginner's Approach To Plein Air Painting
Plein air painting intrigues and intimidates the heck out of me. I thoroughly enjoy the time out in nature painting en plein air, but I end up moaning with frustration as to painting what is in front of me. When it comes to painting outside I get so overloaded with "information" that I just freeze up and have no idea how to proceed. But I've never been one to quit easily, so I'm inching my way into plein air painting very, very gently. I hope … [Read more...]
Glazing And Cold Wax Oil Medium Painting Techniques
In this informative video demonstration, artist Pierre Giroux demonstrates how-to enhance your underpainting by using glazing and cold wax medium techniques. Glazing and cold wax medium adds texture and visual depth to oil paintings. I have been exploring the use of cold wax medium and love it! I hope you enjoy this video... If you found this video helpful, you might like some of my own instructional painting videos too. You can see … [Read more...]
Struggling With Your Painting? Turn It Upside Down
Each painting creates its own special set of problems, because each one is its own lesson in itself. As you are painting, you are going to discover things along the way that will alter your original approach. Are you squinting a lot when you are viewing your unfinished painting? Leaning your head to one side, hoping that this will make it all look better? At a loss as to what your next moves are going to be? Like a punch drunk boxer, … [Read more...]
Enjoying My Artist Palette By New Wave
Since college, I haven't painted with a handheld artist palette. In the past, I have found these classic palettes to be cumbersome, uncomfortable to hold, and a chore to clean. So when I received a box filled with two beautiful handmade artist palettes from my Twitter friends at New Wave Fine Art Products, I was a little bit apprehensive about using them! Grateful for the gift, I first decided to test-out the Highland plein air palette while … [Read more...]
New Still Life Painting Workshop with Lori McNee
This workshop was a great success! Hope to see you next time... Come paint with me in January! I am pleased to announce that I will be teaching a week long still life painting workshop in beautiful Sun Valley, Idaho through the Sun Valley Center for the Arts. ***** Still Life Painting with Lori McNee Mon-Fri, Jan 28- Feb 1st, 6-9pm $210/ $260 nonmembers The Center, Hailey Registration deadline: Mon, Jan 14 ***** During your week in Sun … [Read more...]
A 10 Step Approach to Develop a Series of Exhibition Paintings
A lot of thought and exploration goes into developing a series of paintings for an art exhibition. Today, this has been a topic of conversation between my good friend and fellow artist, Shanna Kunz and me. This weekend, Shanna and I are exhibiting together in an all women art show, "8 Broad Brush Stokes". (Come see us in Utah, November 16-17). Shanna and I love to talk 'shop' when we are together. Today, we have been discussing the importance … [Read more...]
The Highland Plein Air Artist Palette by New Wave
Much to my delight, I recently received a box filled with two beautiful artist palettes from my Twitter friends, Kyle and Keith O'Brien of New Wave Fine Art Products. Kyle asked me to test out their Highland plein air palette, plus their mid-size Grand View Confidant. Lately, I've noticed a lot of artists are favoring the handheld artist palette over the artist taboret. I witnessed this last month while painting in Maine with T. Allen Lawson, so … [Read more...]
How To Make Your Own Linen Painting Panels
Save money and learn how to make your own professional looking hardboard panels. In this video demonstration, I will show you just how easy it is. I learned how to easily mount linen or canvas on hardboard last month while painting with master artist, T. Allen Lawson. The supplies you will need: A hardboard panel, cut to the desired size. A piece of linen or canvas, cut to the size of the hardboard panel. Leave about 1/4 … [Read more...]
10 Reasons Why Artists Should Draw More
Most little children love to draw. You can see this 'phenomenon' for yourself. Go into any family restaurant and notice how a box of crayons, and a piece of paper will keep restless children happy. So later, why do so many aspiring artists and even seasoned painters abandon drawing? The fundamentals for both drawing and painting are the same. Yet, the most important factor in drawing and painting is the ability to see. After careful … [Read more...]


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LAWTON, Okla._A Lawton GEO inmate underwent surgery after he was stabbed several times and beaten.
Emergency responders were called to the prison stabbing around 5 P.M. Wednesday.
The victim was stabbed in the chest and stomach several times and was also beaten with a blunt object.
Two suspects were identified. Prison officials believe the fight started during an argument over money.
The victim was identified as Terrill Gurley. He remains hospitalized in serious condition.


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9/3/2014 » 9/7/2014Wonders of Science, Marshalltown, IA
9/5/2014 » 9/6/2014"Truth for a New Generation," Spartanburg, SC
9/19/2014Human Sexuality Conference, Bartlesville, OK
9/19/2014"Darwin, Dawkins and the Divine: Why is biology at the heart of the New Atheism?," Cambridge, UK
9/21/2014"Science & Faith: Are They Really in Conflict?," simulcast multiple locations
9/5/2014 to 9/6/2014
"Truth for a New Generation," Spartanburg, SC. Speakers: Josh McDowell,
Joni Eareckson Tada, Ben Carson, Eric Metaxas and others. First Baptist Spartanburg, 250 E. Main St. Cost. Information.


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© Songza Media, Inc
Warm, rootsy, acoustic music to get cozy with on Thanksgiving.
Bob Dylan,
Patty Griffin,
Fleet Foxes,
Justin Townes Earle,
Basia Bulat
Float on your back into the middle of a beautiful lake. Watch the clouds pass overhead. Keep floating.
Nick Drake,
Neil Young,
Gillian Welch,
Bob Dylan,
Lucinda Williams
Inspired by the female folk pioneers of the '60s, today's female folk artists pay homage while moving the genre in bold new directions. From powerful folk-rock romps to delicate love ballads, these songs are carefully constructed, melodic, and thoughtful.
First Aid Kit,
The Staves,
Hannah Cohen,
Tina Dico
From '70s singer-songwriters and Nashville queens to today's latest acoustic artists, there's just something special about the combination of the female voice and an acoustic guitar.
Joni Mitchell,
The Watson Twins,
Eleni Mandell,
Alison Krauss,
Gillian Welch
Put on your slippers, wrap yourself in a blanket, and get cozy by the fire.
Ray Lamontagne,
Joni Mitchell,
Crosby, Stills, Nash & Young,
The Avett Brothers
Your mornings need a soundtrack. This is music for taking it easy with a newspaper and a big cup of coffee.
The Shins,
The Raveonettes,
The Temper Trap,
Paper Moon
These amicably twangy country-rock songs of the '60s and '70s are perfect for nights spent camping under clear, star-specked skies.
Nitty Gritty Dirt Band,
New Riders Of The Purple Sage,
Gene Clark,
Gram Parsons
A collection of songs featured on the popular country music blog, countryandwestern.tumblr.com. Listen to a mix of good ol' guys and gals, with a sprinkle of modern cowboys and cowgirls.
Johnny Cash,
Waylon Jennings,
George Jones,
Merle Haggard,
Elvis Presley
Listen to all of the artists and songs nominated for a 2011 Americana Music Award.
Robert Plant,
Buddy Miller,
Sarah Jarosz,
Hayes Carll,
Lucinda Williams


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Military Microwaves Supplement
Modular Platform Approach for UWB Radar System Design
Cost-Effective Approach to Simulation for EW Systems
Co-existence Tests for S-Band Radar and LTE Networks
An advanced antenna reflector designed and built by Harris Corp. has been successfully deployed in space onboard the Sirius FM-6 satellite which was designed and built by Space Systems/Loral (SSL) for SiriusXM.
According to a new report by ABI Research, annual shipments of 802.15.4-enabled devices are forecast to grow more than 5X from 2012 to 2018, with a CAGR of over 30%. ZigBee continues to be the primary driver toward standardization and interoperability and will see further strong growth across many markets, accounting for almost 80% of total 802.15.4-enabled device shipments in 2018.
According to Euroconsult's newly released strategic review, Prospects for In-Flight Entertainment and Connectivity, the global in-flight connectivity market is expected to grow over the next 10 years, with over 12,000 commercial and 16,000 business airplanes to provide in-flight connectivity to passengers by 2022. With a take-up rate of less than 5 percent, in-flight connectivity services generated less than $300 million in revenue from airline passengers last year. The market is expected to grow to $1.3 billion by 2022.
The wireless sensor network market, led by ZigBee, grew ten-fold from 2007 to 2010 and exceeded 45 million annual shipments in 2011. "Strong growth is expected for 2012 and beyond as ZigBee pervades the home automation and home entertainment markets, whilst Smart Meters continue to be rolled out across the globe," commented Peter Cooney, wireless connectivity practice director.
Copyright ©
Get access to premium content and e-newsletters by registering on the web site. You can also subscribe to Microwave Journal magazine.


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News[View RSS]
Kirk Cameron 'Kicks Ass' to Save Christmas
Kirk Cameron is out to get Santa Claus. And this time, it's personal.
Fla. Supreme Court Asked to Rule on Gay Marriage
Florida's highest court is being asked to rule on whether the state's ban on gay marriage is constitutional.
Twittersphere Slams ESPN Over Showering with Michael Sam Segment
Sports reporting hit a new low last week when reporter Josina Anderson took time out of a segment aired on ESPN about how Michael Sam is adjusting to life in the NFL to focus on how his teammates are handling being in the shower with a gay player.
Robertson: 13-Year-Old is Gay Because of Single Mom, Suggests More Men in His Life
"Blame the mom and bring on the men" was televangelist Pat Robertson's answer to a mother concerned about her 13-year-old stepson who confessed to having crushes on other boys.
Hoffman's Friend Sues Enquirer Over Gay & Drug Story
A friend of Philip Seymour Hoffman filed a lawsuit Wednesday against the National Enquirer's publisher, America Media Inc., for a story the tabloid newspaper published that alleged the late actor and he were gay lovers.
EDGEFridays @ Club Cafe :: January 31, 2014
It was the last Friday of the month. See who came out to EDGEFridays @ Club Cafe!
Entertainment[View RSS]
Red vs. Vee: An Interview with OITNB's Kate Mulgrew and Lorraine Toussaint
On June 21, the cast of "Orange is the New Black" assembled in Manhattan at the delightfully eccentric Crosby Street Hotel. Out of that day came the opportunity to conduct an exclusive, in-depth Q&A with stars Selenis Leyva and Kate Mulgrew.
Reeling Opens with 'Boy Meet Girl'
Celebrate 32 years of The Chicago LGBT International Film Festival, Reeling Film Festival on Thursday, September 18th at The Music Box Theatre with a screening of "Boy Meets Girl."
Lizzy Caplan and Michael Sheen on 'Masters of Sex'
The hit Showtime series "Masters of Sex" chronicles the pioneering sexual behavior research by Dr. William Masters and Virginia Johnson that help make the sexual revolution. EDGE spoke to the series' stars Michael Sheen & Lizzy Caplan.
Former Miss Spain Reveals She's Gay
A former Miss Spain announced this week that she is lesbian, making her what some are saying is the first out national beauty queen.
Remarriage Equality: Cheyenne Jackson To Take Second Trip Down The Aisle
Merely six months after announcing his divorce after a two year marriage and a 13-year relationship with husband Monte Lapka, Broadway bad boy and now serial monogamist Cheyenne Jackson confirmed rumors of his engagement to new beau Jason Landau.
Dallas Buyers Club
Please dear God, let both Matthew McConaughey and Jared Leto win Oscars for their career-turning performances in this highly recommended film.
Anti-Cancer Drug Attacks Hidden HIV Reservoirs
A pilot study by HIV researchers from Aarhus University and Aarhus University Hospital in Denmark has shown that an anti-cancer drug can activate hidden HIV.…
Police Arrest Five in Anti-Gay Attack Before Manchester Pride
The police have arrested five people in an alleged hate crime on Canal Street that happened days before Manchester Pride, one of the biggest gay events in the UK.
Kat Coric
Coric is an ardent activist supporting LGBT rights and HIV/AIDS awareness. A multidisciplinary artist, Coric stands out as a heterosexual female artist in the gay Circuit party subculture.
HIV+ Need to Skip Caffeine for a Real Boost
HIV+ and way too tired? Look to complex carbs, protein, fat and some key vitamins for a better boost than stimulants.


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BEIJING: Noted Indian scientist Dr C N R Rao has been conferred with China's top science award for his important contributions in boosting Sino-India scientific cooperation.
Chinese Academy of Sciences (CAS) yesterday gave its 2012 Award for International Scientific Cooperation to three scientists from India, Germany, and Russia.
Rao, 79, founder of Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bangalore, shared the 2012 award with Herbert Jaeckle of Germany's Max Planck Society and Russian space physicist G A Zherebtsov.


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We are glad to bring you to Audiko, where you can easily search for free ringtones for your Android smartphone. Today we have a ringtone of "projet x" by Kid Cudi as well as 5491 other ringtones by Kid Cudi. You can listen to all 20 Kid Cudi – "projet x" ringtone variations available here and download it for free to your computer. You can also explore other 7 albums produced by Kid Cudi for all time. "projet x" is referred to Hip-Hop, and we have a huge amount of Hip-Hop albums absolutely for free. And finally, we have collected lyrics for this track and you can view it here as well. So feel free to browse, listen, download ringtones at Audiko.net. Make your phone sound cool!
Kid Cudi projet x Ringtone
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New ringtones
- penguin cafe - RADIO BEMBA
- Arcangel Ft. De La Ghetto, Plan B, Daddy Yankee Y Nicky Jam - Tremenda Sata (Official Remix)
- Lucinda Williams - Essence
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- melissa steel - Kisses For Breakfast (feat. Popcaan)
- Rae Sremmurd - No Flex Zone
- Fuse ODG - Dangerous Love (feat. Sean Paul)
- Luke Sital-Singh - Bottled Up Tight
- MK - Always (feat. Alana)


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Book online or call +44 (0)1775 843417 at standard rates.
Chalet du Soleil "Julietta" is located next to the ski lift in Les Menuires, just a 20-minute drive from Val Thorens. It offers a sauna, Turkish bath and ski storage with boot drying facilities. The apartments at Chalet du Soleil combine a contemporary and Savoyard style. Each one is complete with a balcony and a large living room with an LCD TV and DVD player. Meals can be prepared using the oven, stove and microwave in the apartment's kitchen. A dishwasher and refrigerator are also provided for your convenience. Free Wi-Fi access is available in the entire property and 1 underground parking space is free per apartment. Moûtiers Train Station is 27 km away.
Our secure connection ensures your details are protected.
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You will pay absolutely no booking fees - You pay the hotel direct and
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Chalet du Soleil "Julietta".
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Infotel™ is a division of Infotel Solutions Ltd.
Copyright © 2014. All rights reserved.
Registered Office: Infotel Solutions Ltd, Boston Road, Gosberton, Spalding, Lincs UK PE11 4NR For further information visit www.infotelsolutions.com


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Book your room at Pai Vista
Comfort Room, 1 Double or 2 Single BedsMax Occupancy: 3 guests (up to 2 children, 1 infant)
Luxury Room, 1 Double or 2 Single BedsMax Occupancy: 3 guests (up to 2 children, 1 infant)
SuiteMax Occupancy: 6 guests (up to 2 children, 1 infant)
Mysore hotel with a restaurant
Situated in Mysore, this hotel is close to Maharaja's Palace, Jaganmohan Palace and Art Gallery, and Jayachamarajendra Art Gallery. Also nearby are St. Philomenas Church and Mysore Zoo.
Hotel Features
In addition to a restaurant, Pai Vista features a fitness center. Other amenities include a bar/lounge and a coffee shop/café.
Room Amenities
Televisions come with cable channels. Guestrooms also feature air conditioning, minibars, and coffee/tea makers.Information missing or incorrect? Tell us!
Pai Vista
At your hotel
Pai Vista features a fitness center and a seasonal outdoor pool. Dining options at the hotel include a restaurant and a coffee shop/café. A bar/lounge is on site where guests can unwind with a drink. Guests can enjoy a complimentary breakfast. High-speed wireless Internet access is complimentary.
A business center is on site at this 3.5-star property. This Mysore hotel also offers tour/ticket assistance, laundry facilities, and 24-hour room service. Onsite valet parking is complimentary.
- Total number of rooms - 66
- Number of floors - 4
- Bar/lounge
- Business center
- Coffee shop or café
- Free breakfast
- Elevator/lift
- Fitness facilities
- Tours/ticket assistance
- Laundry facilities
- Free valet parking
- Restaurant
- Room service (24 hours)
- Safe-deposit box at front desk
- Free Wi-Fi
- Outdoor seasonal pool
Stay connected
Available in some public areas: Free Wi-Fi
Park your car
Free valet parking
In your room
- Air conditioning
- Minibar
- Coffee/tea maker
- Private bathroom
- Hair dryer
- Television
- Iron/ironing board (on request)
- Cable TV service
Eat and drink
A complimentary breakfast is offered.
Pai Vista has a restaurant on site.
24-hour room service is available.
Recreational amenities at the hotel include a fitness center and a seasonal outdoor pool.
The fine print for Pai Vista
When you arrive
Check-in time starts at noon
Special check-in instructions:
When you leave
Check-out time is noon
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.


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JPMorgan Chase & Co. and The Water Council have entered into a partnership to bring together North America's investment community and water technology entrepreneurs to match capital with water innovation.
more News & Articles
more Blog Posts
What is the value of water? It turns out that the answer to that question is not straightforward. While the element water - two hydrogen atoms attached to one oxygen atom - is simple, water as a resource is highly complex and filled with contradictions. Water is abundant yet scarce; priceless yet "free," life-sustaining yet if contaminated, life-threatening.
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14901 Quorum Drive, Suite 425
Dallas, TX 75254
(972) 687-6700
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'Fairy Tale' Home Is Just Plain Magical (House of the Day)
6 Steps Renters Should Take Before Signing a Lease
Housing Market Recovery Finally Back on Track?
5 Mistakes to Avoid When Refinancing
In a Bidding War? 5 Ways to Win the Home You Want
Robin Williams' Lingering Legacy: A Napa Valley Wine Estate
Ashton Kutcher Sells Sleek Bachelor Pad for $9.925 Million
Sale of New York's Plaza Hotel Could Subject It to Boycott
J.D. Salinger's Former House Listed for Sale


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