text:
Kevin Hart's got a bone to pick with Black women everywhere: He wants you to stop talking about his life like you know him!
"Black women assume they know your life, that's the funniest thing about black women," Kevin told MadameNoir.com.
"I got into an argument the other day—and it doesn't matter your race, whether its black or white but it was a black girl—and the girl was like 'you're a piece of s**t. It's funny you just got divorced and you've been with this girl for four years,'" he recalled.
Kevin broke down his romantic timeline, explaining that he didn't leave his wife for his current girlfriend. In fact, he implied that there was a decent gap of time between the two relationships.
"My divorce took me two-and-a-half years! I've been separated for damn near six-and-a-half years! But everybody assumes they know. These things, you laugh at. It's people's opinions. You just take 'em and laugh and say, 'Oh, you know, you're right, you know. You're me.'"
The one person he does not have a problem talking about his life is his ex-wife Torrei Hart, who is very open about their relationship with the media. But there's a big reason that she can get away with talking about him.
"Here's the difference. I respect my ex-wife. She's the mother of my kids, which is why I never bad talk her. Regardless of what she says or what she gives the media, she's the mother of my kids," said Kevin. "So, I'll never talk bad about her."
You might also like:
Torrei Hart spoofs Kevin again
Kevin Hart apologizes about DUI arrest
Torrei Hart talks divorce from Kevin Hart
Kevin Hart's ex-wife gets faux reality show
VIDEO: Kevin Hart's top 5 moments from 'SNL'


text:
A case review has begun following the conviction of 18-year-old Opemipo Jaji from Edmonton for the rape of an 11-year-old girl.A Probation Service spokesperson said: "Our deepest sympathies are with the victim and their family following this horrific crime.
"A Multi-Agency Public Protection Arrangement (MAPPA) Serious Case Review into what happened in this case has been launched. It would be inappropriate to comment further until this is completed."

subset: commoncrawl


text:
Lakers Roster 2013 2014
Los angeles lakers - schedule, See the los angeles lakers schedule and results. change to calendar view or full list view.. Lakers 2014-15 roster - nba.com, Los angeles lakers team news this site uses cookies and similar technologies to customize and enhance your online experience.. Los angeles lakers current roster 2014-2015, Los angeles lakers current roster, including new players, pictures, draft picks and playoff roster for the 2014-15 nba season..
Los angeles lakers 2013-2014 schedule and results, 2013-14 los angeles lakers regular season schedules, with opponent teams, time, tv and game results.. La lakers tickets - 2014-15 lakers schedule | vivid seats, Vivid seats specializes in los angeles lakers ticket sales for every basketball game on the la lakers schedule. find detailed seating for the staples center and enjoy. Los angeles lakers 2015 schedule - lakers home and away - espn, View the complete los angeles lakers team schedule on espn.com. includes home and away, preseason, regular season, playoff and printable schedules..
2013-14 los angeles lakers roster and stats | basketball, Stats and results for players, teams, leaders and scores from the first game ever to yesterday. Salt lakers basketball 2013-2014 - (south jordan, ut, The salt lakers basketball club is the premier organization for varsity, 7th and 8th grade girls basketball along the wasatch front. the organization provides a. Los angeles lakers basketball clubhouse - espn, Los angeles lakers scores, news, schedule, players, stats, photos, rumors, and highlights on espn.com.


text:
A MAN suffered minor injuries in a boat crash during a race at Lake Eppalock.
The incident occurred shortly before 4pm Sunday and paramedics were called.
Ambulance Victoria spokesman John Mullen said the man was in his 50s.
"The boat has apparently flipped," Mr Mullen said.
"He's ended up with some back soreness and he's got some lacerations on his face and a laceration on his hand."
Mr Mullen said paramedics took the precaution of spinal imobilisation because of the speed of the boat and the nature of the incident.
"They put a neck brace on him and used a spinal board," he said.
"He was taken to the Royal Melbourne Hospital in a stable condition for further assessment."
Victorian Speed Boat Club member Brad Nankervis said the man was contesting a support race in the E.C. Griffith Cup.
Mr Nankervis said the weekend-long event went well otherwise, with competitors travelling from across the country.
The winning boat was GP1, driven by Grant Harrison of Melton.


text:
User Reviews for Nabilone
Also known as: Cesamet
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Nabilone.
|Avg. Ratings
|2 reviews
|72 medications
|Nausea/Vomiting, Chemotherapy Induced
|0 reviews
|47 medications
|Summary of Nabilone reviews
|2 reviews
Reviews for Nabilone
Review by ibangdrum:
|User Rating:
For Fibromyalgia: It did take 4-5 days of using this medication before the positive effects appeared. It is working well with very slight side effects, mostly extreme dry mouth & disturbed sleep (odd thoughts & dreams). I have been taking this now for 2 months and will continue with it as long as my Doctor agrees.
|3 users found this comment helpful. Did you? Yes No
|Report as inappropriate
July 15, 2013 2:48 PM
Review by Anonymous:
|User Rating:
Cesamet (nabilone) for Fibromyalgia: No side effects other than increased appetite during my first week of treatment, hugely increased quality of life. Can't sing Cesamet's praises enough!
|21 users found this comment helpful. Did you? Yes No
|Report as inappropriate
November 16, 2011 1:36 PM
More about nabilone
Consumer resources
- Other brands: Cesamet


text:
executive in the securities industry, Harry Markopolos, contacted the SEC's Boston office in May 1999, urging regulators to investigate Mr. Madoff. Mr. Markopolos continued to pursue his accusations over the past nine years... and according to documents he sent to the SEC that were reviewed by The Wall Street Journal. (emphasis added)It's not a matter of mere dishonesty. Or at least, not merely Mr. Madoff's.
Note: Help maintain a healthy, respectful discussion by focusing comments on the issues, topics, and facts at hand—not at other members of the site.I'm not going to flag your comment as an offensive vulgar ad hominem attack, but I really should.
Mr Madoff has been charged with a single count of securities fraud. He declined to enter a plea in Manhattan's US District Court and was released on $10 million bail. He faces up to 20 years in jail and a $5 million fine if convicted.Sorry, I made that last part up. I couldn't resist.
In other news, a man robbed a gas station at gun point, stealing $500 dollars. He was soon thereafter arrested, and if convicted, will be forced to pay $0.50 in fines.
Some crimes are too perfect. Some facades too well-painted to be original or convincing. A good hustler knows he must lose sometimes in order to win. THAT is the reflection of reality that makes it believable, and gives confidence to the punter who will shortly be taken out. THAT was what was wrong with Bernie Madoff's ponzi. The people who were taken - like the Family Office and many others investors who in time will go public on their fleecing - wanted badly to believe they were onto to something that was so good that they ignored the most obvious signs of bogusness. It just didn't make sense. It just didn't add up. Even Jim Simons earns it. There is no free lunch.There's an interesting discussion in the comments (I'm in there too, fwiw) as well.
"There has been such a rush to try and get into the next hot hedge fund that some people are obviously not doing their homework as diligently as they should be."What else can you conclude? People get greedy, don't do their due diligence and end up losing money.
There is something fitting and just in the timing of this. It is emblematic of America since Reagan and the Great Leveraging. Something for nothing. Thank you Mr Laffer. But as a philosophy and modus operandi it is quite literally, bankrupt and without merit. And Laffer has since been proven to be full of shit. Now, Americans will have to confront this, the premise that greed is good and self-guiding and somehow omnisciently beneficial for it has had repurcussions down to the core of our society and values. "Sorry everyone....what you've been pursuing has all been a lie, a big ponzi, a rat-hole to nowhere....". Re-boot.posted by psyche7 at 1:15 PM on December 13, 2008 [1 favorite]
The two sons, Andrew and Mark, have worked for the securities firm since graduating from college 20 or so years ago. Neither is involved in the asset-management business that their father runs, according to a person familiar with the situation.But perhaps I am being naïve.
"As of November 1, 2008, assets under management at FGG totaled approximately $14.1 billion, of which approximately $7.5 billion was invested in vehicles connected to Bernard L. Madoff Investment Securities."We call it concentration risk, and presumably Fairfield knew what they were doing. It will be interesting to see how their investors react.
(cur) (last) 08:22, 15 December 2008 18.104.22.168 (Talk) (58 bytes) (←Replaced content with ' JEW') (undo)posted by Sonny Jim at 12:28 AM on December 15, 2008
"The fraud may not have been the work of Rene-Thierry Magon de La Villehuchet, but it came on his watch. For a man with a deep sense of rectitude, that was shame enough.NBC reports that 75% of his company's investment fund and strategy was with Madoff in whom he had developed (misguided) trust over the years.
Friends and colleagues tried to console the fund manager, the scion of French aristocracy who despaired after losing more than $1 billion of his wealthy clients' money in the Ponzi scheme allegedly run by Wall Street wizard Bernard Madoff.
'Listen, people make mistakes,' Leon Cooperman, founder of hedge fund Omega Advisors, said he told de La Villehuchet in a telephone conversation Monday. 'You're not at fault and you have to pick yourself up from this.'
But when a security guard opened the door to de La Villehuchet's office at Access International Advisors the following morning, he found the businessman dead at his desk, both of his wrists slashed. A box cutter and a bottle of sleeping pills lay nearby. Police say it was a suicide."
« Older How to best show your love if you're a rockabilly ... | The Turn... Newer »
This thread has been archived and is closed to new comments


text:
Radical Islamic Voter Drive
Radical Islamic front group MPAC (Muslim Public Affairs Council) has mutated into something called the Muslim American Society Freedom Foundation, and is launching a campaign to register millions of Muslims in America and mobilize them to vote in the 2004 elections: Muslim-American Group to Mobilize Voters. (Hat tip: Doctor Bean.)
"Campaign V.I.P: Voting is Power" is aimed at registering some 2.5 million Muslim-Americans, said Mahdi Bray, the group's executive director. Mosque surveys estimate 750,000 Muslim-Americans are currently registered, he said on the eve of the campaign's start.
"Many, when they come to this country, tend to become insular," Bray said. "We're trying to get people out in the communities and active in the civic process. We want them in parent-teacher associations, rotary clubs, public service organizations."
He said there are 7 million Muslim-Americans.
Once again we see Mahdi Bray attempting to promote the vastly inflated figure of "7 million" Muslims; realistic estimates put the number at more like 3 million.
Mahdi Bray is well-known at LGF; at last year's anti-war rallies at the National Mall, he stood on stage and cheered as CAIR representative "Dr." Ghazi Khaksan announced, "I bring to you salaams and greetings from the Mujahadeen at CAIR." Steven Emerson's book American Jihad has the following information about Bray, giving good reason to be concerned about the agenda he and his Saudi Wahhabi backers will push in this voter registration drive:
On December 22, 2000, MPAC's Mahdi Bray organized a rally in Lafayette Park outside the White House to celebrate a "Worldwide Day for Jerusalem." In Arabic, the crowd responsively chanted with the emcee, "Khaybar, Khaybar oh Jews, the Army of Muhammad is coming for you!" Posters calling for "Death to Israel" and equating the Star of David with the Nazi swastika were openly displayed and anti-Semitic literature calling for the destruction of the Jews and Israel was distributed. Members of the crowd burned the Israeli flag while marching from the White House to the State Department.
Bray spoke at this rally, along with Imam Mohammed al-Asi, former director of the Islamic Education Center in Potomac, Maryland, who exhorted the crowd to violence in the name of Islam. Al-Asi said, "Now, all our khatibs (speakers), our imams, our public speakers, should be concentrating on militarizing the Muslim public. This is not a time to make a speaking issue out of this … Muslims have to familiarize themselves with every means possible … Rhetoric is not going to liberate Al Quds and Al Aqsa. Only carrying arms will do this task. And it's not going to be someone else who is going to carry arms for you and for me. It is you and me who are going to have to carry these arms."
Notice that the rally described above occurred before the 9/11 attacks, when Bray and the MSA and MPAC and CAIR were much more open and unguarded about their hatred. They've learned to conceal their true faces a little better now.


text:
Two Detroit men were arrested on heroin charges in Kanawha County, WV after police executed two search warrants on two apartments in Big Eagle Apartment Complex in Jefferson, WV on March 23.
Keival L. Kelley and Steven Walker, both of Detroit, were charged with possession of heroin with intent to deliver after police discovered about one ounce of heroin during the search.
Police also found a large amount of cash and a loaded pistol with extra ammunition. The pistol was found in Walker's apartment.
Federal charges may be brought against Walker due to prior felony convictions.
Both men were taken to South Central Regional Jail on a $25,000 full surety bond.


text:
Killeen News
Local news for Killeen, TX continually updated from thousands of sources on the web.
18 hrs ago | KWTX
Woman Killed In Late-Night Crash
Investigators with the Texas Department of Public Safety will continue investigating Wednesday after a late-night fatal accident in Coryell County.
US army base shooting: Soldier open fire leaves 3 killed, 11 injured in Texas
Washington, April 3: A soldier opened fire at Fort Hood, an army base in Texas and scene of a massacre in 2009, killing three people and wounding at least 11 others before taking his own life.
Killeen May Consider Banning Housing Undocumented Immigrants
"It is necessary that we bring it up now rather than later so that later we won't be reacting rather we will be responding," said Okray.
Fort Hood seeing more women in command
Col. Patricia Darnauer never noticed she was the only female brigade-level commander at Fort Hood until all 18 leaders came together.
Occupants displaced after Killeen apartment fire
Occupants in 10 units at the Summer Place Apartments on 1701 N. College St. in Killeen were evacuated after a fire broke out there a little after 2:30 p.m. this afternoon.
Suspect Shot, Police Officer Hurt During Pursuit
According to Killeen police, the officer attempted to stop a silver Nissan in the area of Elms Rd. and Ft.
Killeen officer hit by vehicle, suspect shot
A Central Texas police officer was hit by a fleeing vehicle but managed to shoot the driver who was later caught.
Killeen Police officer injured by fleeing suspect
The incident occurred around 5 a.m. when the officer was trying to stop a silver Nissan near Elms Rd. and Ft.
Killeen: Traffic Light Outages Present Morning Commute Problems
Killeen police were dealing with non-functioning traffic signal lights Friday morning at some busy intersections and traffic was backing up at some locations.
Killeen man accused of kidnapping daughter
Edgar Lewis Bradshaw, Jr., 48, was arraigned by Bell County Justice of the Peace Bill Cooke on Tuesday for aggravated kidnapping.
2 dead in Texas in apparent domestic dispute
Police say the people were found with gunshot wounds outside a Temple residence Tuesday night.
Seven Arrested in Connection to Bell County Burglaries
Among the arrested was Lane Andrew Pickle, a 27-year-old soldier on Fort Hood. He was arrested because his DNA matched an item of clothing left at one of the crime scene.
Killeen, Copperas Cove given water quality violations
Each year the Texas Commission on Environmental Quality works with cities to put out annual water reports.
Shots Fired As Local Resident Chases Would-Be Burglars
Shots were fired early Monday in a Killeen neighborhood as a resident chased two men he caught attempting to break into his car.
Four Teenagers Arrested After Chase, Crash, Foot Pursuit
Killeen police were searching Monday for a male suspect who ran after the car he was driving crashed during a police chase.
Texas Education Agency Releases Accountability Ratings
The Texas Education Agency released their 2014 accountability ratings on Friday, and ten Waco schools on the list need improvements.
Suspect Surrenders After Armed Standoff In Killeen
An armed suspect was in custody Friday morning after a standoff in Southeast Killeen during which a woman was held hostage.
Short standoff ends peacefully in Killeen
A 31-year-old man was taken into custody after he was involved in a standoff with police at a Killeen home Friday morning.
Man guilty of manslaughter in shooting
A Killeen man was found guilty of manslaughter Thursday in a deadly downtown Austin shooting during Texas Relays weekend in March 2013.
We Won't Back Down': HB 2 on TrialAbortion clinics fight to stay open
In day two of the trial to block provisions of Texas' abortion-restrictive House Bill 2 , a local reproductive health care provider recounted the increased state regulator visits following her involvement with the first lawsuit against HB 2, filed in 2013.
Killeen News, Events & Info
Updated: Wed Aug 20, 2014 03:28 am
Copyright © 2014 Topix LLC


text:
CNBC: Why not, if you had nothing to do with this murder, why not turn yourself in? Have a lawyer, you go in with security guys, you can go in with cameras, why not go in and tell them you don't know about the murder? John McAfee: Because it's fine to go in with security. It's fine to go in with cameras. But when I am detained, you are not allowed to go into the jail cell with me. This is where people simply disappear. They choke on their own vomit or hang themselves or are beaten to death by fellow prisoners. If you've done any research on Belize and the legal and police system, you will discover disastrous results. CNBC: Do you really think they would kill you? McAfee: Absolutely, I do, sir. CNBC: What have the last five days [in hiding] been like? McAfee: They've been okay. I don't have a lot of freedom of movement. The food is not best. I have no television. I would like a television. [CNBC via BI]
- 16 Nov 2012 at 6:25 PM
McAfee Founder/Fugitive Wanted For Murder Misses TVBy Bess Levin
- 28 Aug 2014 at 8:00 AM
Posted in:
Sponsored Content
$5,000,000 Up For Grabs 1-Week Fantasy FootballBy Draft Kings
Football is back, and 1-week fantasy juggernaut DraftKings.com is offering a guaranteed $5,000,000 in prizes.
DraftKings has a special offer for Dealbreaker readers—make a first time deposit and get free entry into a $100,000 contest.
Or if you're a high roller, you can pay $200 to compete for $1,000,000 in prizes in the NFL Sunday Million contest.
So what is 1-week fantasy? On DraftKings, it's simple. You draft a new team every time you want to play. Choosing from the list of available players, you pick the best possible team under DraftKings' allotted salary cap. Payouts are instant and completely secure, and DraftKings is 100% legal.
Click on any of the links in this article to claim your free entry into the DraftKings $100,000 Week 1 contest.
Popular Posts
- McAfee Founder/Fugitive Wanted For Murder Misses TV November 16, 2012
- Swiss Bankers Suddenly Bashful About Listing "Sparkling Water," "Hooker For Client" On Expense Reports August 29, 2014
- Every Second Of Jefferies CEO's Ice Bucket Challenge Is Better Than The Last August 27, 2014
- Get Ready To Hear "I'll Have My Assistant Make A Reservation At Denny's" A Lot More Often August 29, 2014
- Kyle Bass Not Entirely Thrilled With Paul Singer At The Moment August 28, 2014
- Horror In The Hamptons: Rosé Shortage Edition August 27, 2014
- Opening Bell: 08.29.14 August 29, 2014
- Steve Ballmer Offers Primer On How To Buy A Major League Sports Team August 26, 2014
- Write-Offs: 08.29.14 August 29, 2014
- Pay Hike Watch '14: Raises For Everyone (Under 25)! August 21, 2014
Contact Us
Editorial Staff
- Executive Editor
- Bess Levin
How Can We Help You?
- Send tips to:
- For tech issues email:
- For advertising or events email:
- For research or custom solutions email:
- Dealbreaker is published by Breaking Media.
For a full list of our sites, services and staff visit breakingmedia.com


text:
Terms of Use | Privacy Policy
Blog | About | Contact | Submit Mod | Join Mod DB | Site Map | Media Kit | RSS
© 2002 - 2014 DBolical Pty Ltd. All Rights Reserved. 4256 modders.
I'm just a Half-Life mapper. Despite the age of the old HL engine, I still enjoy trying to push the limits when creating maps for it.
We're sorry, but no downloads were found matching the criteria specified. We suggest you try the download list with no filter applied, to browse all available files.
If you would like to share files with the community, sign up and you can.


text:
Feedback-Seeking Behavior as a Self-Regulation Strategy for Creative Performance
AbstractUsing a sample of 456 supervisor-employee dyads from 4 organizations, this study examined how employees use feedback seeking as a self-regulation strategy to manage their creative performance. As hypothesized, employees' cognitive style and perceived organizational support for creativity affected two patterns of their feedback seeking, i.e. their tendency to inquire for feedback from various sources and their propensity to monitor their environment for indirect feedback cues. Feedback inquiry from various sources further related to supervisor ratings of employee creative performance. These results highlight the importance of studying employees' self-regulatory behaviors in the creative process and support the proposition that feedback seeking is not only a strategy that facilitates individual adaptation, but also an individual resource that can help individuals to achieve creative outcomes.
Download InfoIf you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
Bibliographic InfoPaper provided by Ghent University, Faculty of Economics and Business Administration in its series Working Papers of Faculty of Economics and Business Administration, Ghent University, Belgium with number 08/533.
Length: 47 pages
Date of creation: Sep 2008
Date of revision:
Handle: RePEc:rug:rugwps:08/533
Contact details of provider:
Postal: Hoveniersberg 4, B-9000 Gent
Phone: ++ 32 (0) 9 264 34 61
Fax: ++ 32 (0) 9 264 35 92
Web page: http://www.ugent.be/eb
More information through EDIRC
Related researchKeywords: SELF-REGULATION; FEEDBACK-SEEKING BEHAVIOR; EMPLOYEE CREATIVITY; COGNITIVE STYLE; PERCEIVED ORGANIZATIONAL SUPPORT FOR CREATIVITY;
This paper has been announced in the following NEP Reports:
- NEP-ALL-2008-09-29 (All new papers)
- NEP-CBE-2008-09-29 (Cognitive & Behavioural Economics)
- NEP-CSE-2008-09-29 (Economics of Strategic Management)
ReferencesReferences listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- De Stobbeleir, K. & Buyens, D., 2008.
"The feedback-seeker in his social labyrinth: the mediating role of goals and cooperative norms in linking empowering leadership to feedback-seeking behavior,"
Vlerick Leuven Gent Management School Working Paper Series
2008-13, Vlerick Leuven Gent Management School.
- K. E. M. De Stobbeleir & S. J. Ashford & D. Buyens, 2008. "The Feedback-Seeker in his Social Labyrinth: The mediating role of goals and cooperative norms in linking empowering leadership to feedback-seeking behavior," Working Papers of Faculty of Economics and Business Administration, Ghent University, Belgium 08/534, Ghent University, Faculty of Economics and Business Administration.
ListsThis item is not listed on Wikipedia, on a reading list or among the top items on IDEAS.
StatisticsAccess and download statistics
CorrectionsWhen requesting a correction, please mention this item's handle: RePEc:rug:rugwps:08/533. See general information about how to correct material in RePEc.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Nathalie Verhaeghe).
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If references are entirely missing, you can add them using this form.
If the full references list an item that is present in RePEc, but the system did not link to it, you can help with this form.
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your profile, as there may be some citations waiting for confirmation.
Please note that corrections may take a couple of weeks to filter through the various RePEc services.


text:
It's been a busy week and will be a busy weekend for us. We just celebrated my daughter's birthday yesterday and still have lots to clean up. I'm starting to work on a project, making four circle skirts for four little girls to wear at a play for our local church and this weekend we will have a special service at our church to celebrate the Lord's Supper. Busy Busy! So I don't want to neglect my blog and thought I would share my favorite recipe. I got this recipe from the Whole Foods website but substituted and added some ingredients and made it my own but kept their title cause it sounds so much cooler than just oatmeal raisin cookies:
This recipe says it makes 2 dozen cookies but if you like your cookies nice and chunky like I do, then you will really have 14-16 big and chunky cookies.
(note: my changes to the original recipe are in bold, to view the original recipe click Here)
4 tablespoons (1/2 stick) butter, softened
3 tablespoons olive oil
3 tablespoons olive oil
1/2 cup evaporated cane juice sugar
1 egg
2 teaspoons vanilla extract
1/2 teaspoon sea salt
1 cup quick cook or old-fashioned rolled oats
1/4 cup ground flax seed
1 cup whole wheat pastry flour
3/4 teaspoon baking powder
1/2 cup seedless raisins
1/2 cup of original applesauce
1/2 cup toasted pecans, finely chopped
Preheat oven to 375°F. Line 2 large baking sheets with parchment paper; set aside.
In a large bowl, whisk together butter and oil until completely blended. Whisk in sugar, egg, vanilla and salt; set aside. In a second large bowl, combine oats, flax seed, flour and baking powder, then add to butter mixture and stir in applesauce, pecans and raisins mixing well to combine thoroughly.
Drop dough by the spoonful onto prepared baking sheets, spacing them about 2 inches apart, and bake until cooked through and golden brown, 10 to 15 minutes. Carefully transfer to wire racks and set aside to let cool completely.
Serve with a glass of milk or cup of coffee and Enjoy!
Serve with a glass of milk or cup of coffee and Enjoy!
Linking up these parties Here


text:
Demo Boys Check Boardshorts (2 Pack)
- In Stock
2 reviews
- Delivery
- Next day delivery available
Boys 2 pack boardshorts, one with printed check design.Colour: Multi Check. Polyester. Machine washable.
Disney Jake and the Never Land Pirates Sunsafe
- Low stock, selling fast
6 reviews
- Delivery
Jake and the Never Land Pirates Sunsuit
Before your little pirate heads for the seven seas this summer, make sure he's wearing his Jake and the Never Land Pirates sunsuit to keep him covered up.
The all-in-one keeps his body, arms and legs covered and he'll love the way it makes him look as if he's dressed as Jake with its printed pirate suit design. Whether he's setting sail at the beach, or playing with land lubbers by the pool, he'll look ship shape!
Useful info:
- Jake and the Never Land Pirates Sunsuit
- Printed pirate costume design
- Long sleeves and legs keep him covered
Crafted from a quick-drying cotton-and-nylon blend, these ultra-cool swim trunks have elasticated waist side pockets and patch pocket with a metal drainage grommet at the back. The signature embroidered pony accents the left hem and woven label with 'Polo Ralph Lauren Swimwear' text and a palm tree graphic accent the back waist. Interior mesh brief offers additional support.Colour: Red. Body: 58% cotton, 42% nylon. Lining: Polyester. Machine washable.
Freespirit Pack of 2 Girls Off-The-Shoulder Swimsuits in Black and Leopard – fantastic value!
She'll hit the waves in style this summer in these snazzy swimsuits by Freespirit.
Made from a stretchy and fast-drying fabric, this pack comes with two fab costumes. There's one pair in chic black, plus another in funky leopard, while they both have frilly off-the-shoulder designs in contrasting colours and patterns. Meanwhile, the spaghetti straps help to hold these stylish swimsuits in place.
Useful info:
- Freespirit girls swimsuits
- Great value pack of 2
- 1 black costume and 1 leopard print
- Frilly off-the-shoulder design in contrasting colours and patterns
- Stretchy and fast-drying fabric
- Spaghetti straps
Nike Youth Boys Victory Poly Warm Up Suit
- In Stock
1 review
- Delivery
- Next day delivery available
The Nike Victory T Boys' Warm-Up includes a full-zip mock-neck track jacket and striped athletic pants for a sleek sports look. A brushed interior lends extra warmth and a soft touch to this versatile warm-up. Benefits Mock-neck jacket that zips up to the chin for warmth Rib cuffs for durability and a fit that stays in place Pull-on pants with interior drawcord for a snug, adjustable fit Colour-blocking and contrast piping for athletic style Side slit pockets on jacket and pants for storage.Colour: Black/Blue. Polyester. Machine washable.
Nike Junior Celtic 2014/15 Short Sleeved Away Shirt
- In Stock
0 reviewColour: Green. Polyester. Machine washable.
- Delivery
- Next day delivery available
Ellesse Youth Boys Bts Jacket and Bag
- In Stock
0 review
- Delivery
- Next day delivery available
Youth boys Bts Jacket and bag.Colour: Black. Polyester. Machine washable.
Colour: Red/Black. 70% cotton, 30% polyester. Machine washable.
Peppa Pig Swimsuit with Sunsafe Design
If your little piglet is going to be jumping in the pool rather than the mud this summer, this Peppa Pig sunsafe is a must-pack essential that she'll love.
In summery yellow and pink, it flaunts a cute contrasting frills on the sleeves and ankles, as well as a large-scale graphic of Peppa at the beach, that reads 'Peppa loves... sunny summer days'. The longer sleeves and legs, meanwhile, help to protect her from the sun.
Useful info:
- Peppa Pig Swimsuit
- Sunsafe
- Yellow and pink with contrasting frill
- Large-scale Peppa graphic
- Longer sleeves and legs
adidas Originals Baby Boy Denim Suit
- In Stock
0 review
- Delivery
- Next day delivery available
adidas Originals Baby Boy Denim SuitColour: Blue/White. 70% cotton, 30% polyester. Machine washable.
Minnie Mouse Swimsuit
- In Stock
10 reviewsColour: Multi. Polyester. Machine washable.
- Delivery
Ellesse Little Kids Trophy Tee
- In Stock
1 reviewColour: Blue/White. 65% polyester, 35% cotton. Machine washable.
- Delivery
- Next day delivery available


text:
Orville A. Kallevig Aug. 6, 1934 - Oct. 18, 2008
NEW LONDON -- Orville Arthur Kallevig, 74, of Pennock died Saturday at his home.
The service will be at 10:30 a.m. Wednesday at Evangelical Covenant Church in New London. Burial will be at Lake Florida Mission Cemetery in rural Spicer.
Visitation will be from 4 to 7 p.m. Tuesday at Harvey Anderson Funeral Home in Willmar and for one hour prior to the service Wednesday at the church.
Are you a newspaper subscriber but you don't have a Digital Access account yet? https://secure.forumcomm.com/?publisher_ID=40&event=subscriber/lookup.
You will need your subscription account number and phone number. Not sure if you have an account? Email us at firstname.lastname@example.com and we can help you.


text:
Jimmy Kimmel brought three experts in American Sign Language on his show for a first-ever Sign Language Rap Battle. Wiz Khalifa performed, and man… this is awkward. It's not just white girls dancing. It's white girls dancing and signing.
Tags: american sign language, jimmy kimmel, jimmy kimmel live, sign language, video, wiz khalifa


text:
Product Details
SP10 Matte Black with Clear Coat Wheels by Motegi Racing®. The race-bred wheels from Motegi Racing are designed to perform under the extreme conditions generated by enthusiastic driving of modern performance cars.
The performance wheels from Motegi Racing are of racing pedigree. Modern high performance cars are capable of speeds and cornering that not even extreme racing cars of yesteryear can match. They need race-bred wheels that can perform under the extreme heat generated by supercar brakes and withstand the extreme forces created on cornering and braking.
- Racing Heritage
- Designed for Supercars
- Pure Performance Design
- One Piece Cast Construction
- 1-Year Warranty on Finish*
- Limited Lifetime Warranty on Structure*
- Lip size may vary depending on the size of the wheel
- All wheels are custom made for each customer and are therefore Non-Cancelable and Non-Returnable
- Wheel orders cannot be cancelled after the manufacturing process has begun (usually 24 to 48 hours after order is placed)
*Warranties only apply to original buyer148.63 204.87
Motegi Racing was conceived to develop the most advanced performance wheels through innovations in design and engineering. Through the development of high-quality wheels, Motegi Racing provide to their demanding customers a product that delivers the ultimate performance in racetracks and street. Their technology and design follows a true philosophy of pure performance, allowing the form of the wheel to follow the function necessary to succeed in different racing environments. Whatever your passion in performance automotive is, Motegi Racing is your partner in the pursuit of authentic performance.
Product Reviews (0)
Product Reviews (0)
More Accessories
You will never pay more with CARiD! Not only will we match prices from any competitor's website or other reputable source, we will continue to honor that promise for up to one year after your purchase.
We'll match the price at time of purchase, or refund you the difference if done after the purchase. Either way, we are totally committed to providing you the best online shopping experience.
We're car and truck enthusiasts, just like you! And it's enthusiasts we hire in our Sales and Service Centers. Many of our staff are ASE certified and have spent years in the retail auto business.
We conduct our own in-house training, and we even bring vendors to us for hands-on product training demonstrations. You're getting true expertise when you phone or email us!
With hundreds of vendors, and tens of thousands of components for sale, we put tremendous effort into coordinating our data with our vendors' data in order to guarantee that you get the correct part.
Our huge database is regularly cross-checked to keep it current and optimized. At times, our thoroughness makes our data even more accurate than our suppliers! This rigorous process means that you can always order with confidence.
- There is a high risk of damage when transferring TPMS from your factory wheels to your new aftermarket wheels
- Conveniently receive a fully functional and assembled wheel & tire package without having to do any extra work or incur further costs
- Always have an extra set. Enjoy the convenience of quickly switching between your factory and custom wheels for Snow or Racing
- We have state of the art equipment to "scratch-less" mount and "road force" balance any size wheel and tire that most local shops cannot
- Oro-Tek has been engineering and manufacturing premium quality sensors since the beginning of TPMS
- Save money on installation since we install TPMS sensors at no charge
- Save money on shipping since shipping wheels and tires separately costs substantially more
- Save money on assembly since we mount and balance at no charge


text: CHAPTER 15: CARDIOVASCULAR SYSTEM OBJECTIVES: 1. List the organs that compose the cardiovascular system and discuss the general functions of this system. 2. Describe the location, size, and orientation of the human heart. 3. Define the term cardiology. 4. Describe the structure of the heart in terms of its coverings, layers, chambers, valves, and blood vessels. 5. Name the function of serous fluid around the heart. 6. Give another name for epicardium. 7. Describe the structure and function of the interventricular septum. 8. Explain why the atria are passive chambers, while the ventricles are active. 9. Name the function of heart valves. 10. Distinguish between AV and SL valves in terms of location, structure, and when they close. 11. Define/describe the terms chordae tendineae, papillary muscle, and trabeculae carneae. 12. Name (and locate) the veins that deposit their blood into the atria of the heart (which atria? deox- or oxygenated?). 13. Name (and locate) the arteries that take blood away from the heart (from which ventricle? deox-or oxygenated blood?). 14. Distinguish between pulmonary, coronary and systemic circulation. 15. Track a drop of blood through the following circulations: a. heart/ lungs/ heart; b. through myocardium; c. to the body (in general). 16. Define the terms ischemia and hypoxia, and explain how they are related to the pathologic conditions of angina pectoris and myocardial infarction. 17. Discuss what causes reperfusion damage. 18. Explain the significance of each component of the cardiac conduction system and trace how the cardiac impulse travels through the myocardium. 15-1 CHAPTER 15: CARDIOVASCULAR SYSTEM 19. Name the common term for the sinoatrial (SA) node. 20. Discuss the physiological stages of cardiac muscle contraction and trace how they appear on graph plotting mV vs. time. 21. Explain why the refractory period between cardiac muscle contractions is so long. 22. Trace a typical ECG and label each wave or complex and explain what event of the CCS corresponds to each wave. 23. Name the term referring to all of the events associated with one heartbeat. 24. Define the terms systole and diastole. 25. Outline the phases of the cardiac cycle in terms of what is happening in the ECG trace, mechanical events (contraction or relaxation), atrial pressure, ventricular pressure, ventricular volume, aortic pressure and timing. 26. Discuss heart sounds in terms of what they represent, how they sound, how they are detected and their significance. 27. Define the terms cardiac output (CO), heart rate (HR), and stroke volume (SV). 28. Discuss the factors that regulate heart rate. 29. Explain what is meant by the human cardiovascular system being a "closed system". 30. Define the term hemodynamics. 31. Compare and contrast the 3 types of blood vessels in terms of the following: a. direction of blood-flow (in terms of the heart), b. wall structure (# of layers and components of those layers), c. gas concentrations and d. pressure. 32. Define the term anastomoses. 33. Describe how arterioles play a major role in regulating blood flow to capillaries. 34. Discuss the major event that occurs at capillaries. 35. Compare and contrast continuous, fenestrated and sinusoidal capillaries in terms of structure and location. 36. Define the terms blood flow and circulation time and give the value of the normal circulation time in a resting adult. 15-2 CHAPTER 15: CARDIOVASCULAR SYSTEM 37. Discuss the factors that affect cardiac output. 38. Define the term blood pressure, name the type of blood vessels where blood pressure is significant, and name the normal (average) value in a resting adult. 39. Define the term blood resistance and discuss the three major factors that determine it. 40. Explain the processes by which materials are exchanged through a capillary. 41. Locate the neural cardiovascular center on a mid-sagittal diagram of the brain, explain where impulses sent to it are first detected, and explain where its outgoing impulses are directed and what happens when they get there. 42. List the hormones involved in regulation of blood pressure and blood flow. 43. Define the terms tachycardia and bradycardia. 44. Distinguish between the pulmonary and systemic circuits (circulatory routes). 45. Track a drop of blood through the following: a. from the right fingers to the left ear; b. from the stomach to the left fingers; c. from the right toe to the left kidney; d. from the right kidney to the right side of the brain. 46. Name the branches of the ascending aorta, aortic arch, thoracic aorta, and abdominal aorta, and denote what body region they supply with blood. 47. Explain what happens to the aorta at the brim of the pelvis. 48. Although the venous circuit is essentially parallel to the arterial circuit, list the differences between the two. 49. Name the longest vein in the body and the venipuncture site. 50. Discuss hypertension. 15-3 CHAPTER 15: CARDIOVASCULAR SYSTEM: THE HEART I. INTRODUCTION The major function of the cardiovascular system is to circulate substances throughout the body. In other words, its organs function to supply cells & tissues with oxygen & nutrients and also to remove wastes (CO2 & urea) from cells and tissues. If cells do not receive O2 & nutrients and wastes accumulate, cells will die! Remember this is the cardiovascular system (See Fig 15.1, page 543), which is composed of the heart and blood vessels. Blood, a connective tissue is circulated through these organs. Cardiology is the study of the heart and the diseases associated with it. II. STRUCTURE OF THE HEART A. Location and Size of the Heart: See Fig 15.2, page 543 and 15.3, page 544, and Fig 15.4, page 544. 1. Location = within mediastinum. 2. Size = closed fist; 300g (adult). 3. Base = wide superior border; 4. Apex = inferior point. B. Coverings of Heart = Three membranes: See Fig 15.4, page 544 and Fig 15.5, page 545. 1. Serous Pericardium a. visceral pericardium = innermost delicate epithelium + CT covering surrounding the heart muscle; b. parietal pericardium = inner lining of fibrous pericardium; * Recall the pericardial cavity between a & b, filled with serous fluid for lubrication. 2. Fibrous Pericardium = outermost tough, fibrous protective CT layer that prevents overstretching of the heart. C. Wall of the Heart: composed of 3 layers: See Fig 15.5 and Table 15.1, page 545. 1. epicardium = visceral pericardium; 2. myocardium = cardiac muscle tissue (recall characteristics); bulk of heart; 3. endocardium = smooth inner lining of heart chambers and valves. 15-4 CHAPTER 15: CARDIOVASCULAR SYSTEM: THE HEART II. STRUCTURE OF THE HEART D. Heart Chambers and Valves (Fig 15.6, page 547). 1. The upper chambers are called atria (plural). a. Right and left atrium are separated by the interatrial septum; b. Atria receive blood from veins (PASSIVE); c. are thin walled chambers. * Note that ear-like flaps called auricles cover the atria See Fig 15.4, page 544. * Note the location of the fossa ovalis, which is remnant of the fetal foramen ovale (page 908). 2. The lower chambers are called ventricles. a. Right and left ventricle are separated by the interventricular septum; b. Ventricles pump blood from the heart into arteries (ACTIVE); c. are thick walled chambers. * Note the trabeculae carneae, which is the irregular inner surface (ridges and folds) of the ventricles. 3. Atrioventricular valves (AV valves) See Fig 15.6, page 547, and Fig 15.8 & 15.9, page 548. a. The tricuspid valve lies between the right atrium and ventricle; b. The bicuspid valve lies between the left atrium and ventricle (Mitral Valve); c. Structures associated with AC valves: See Fig 15.7, page 548. o Chordae Tendineae = tendon-like, fibrous cords that connect the cusps of AV valves to the papillary muscle (inner surface) of ventricles; prevent cusps from swinging back into atria. o Papillary Muscle = the muscular columns that are located on the inner surface of the ventricles. 4. Semilunar valves (SL valves) a. The pulmonary SL valve lies within the pulmonary trunk; b. The aortic SL valve lies within the aorta. * See Heart Valve Summary Table 15.2, page 549. 15-5 CHAPTER 15: CARDIOVASCULAR SYSTEM: THE HEART II. STRUCTURE OF THE HEART E. Skeleton of the Heart 1. Rings of dense CT around the four valves 2. Mass of dense CT in the interventricular septum 3. Provide attachment sites for valves and cardiac muscle fibers. F. Major Blood Vessels associated with the Heart See Fig 15.13, page 552. 1. Arteries carry blood away from the heart. a. carry blood that is high in O2 & low in CO2, except pulmonary arteries that are low in O2 & high in CO2; b. Aorta carries blood from the left ventricle to the body; c. Pulmonary arteries carry blood from the right ventricle to the lungs (via the pulmonary trunk). d. Coronary arteries carry blood to the myocardium. 2. Veins carry blood toward the heart. a. carry blood that is high in CO2 & low in O2, except the pulmonary veins that are high O2 & low CO2. b. Superior vena cava brings blood from the head and upper limbs; c. Inferior vena cava brings blood from the trunk and lower limbs; d. Coronary sinus (posterior surface) brings blood from the myocardium; o All of the above deposit their blood into the right atrium! e. Pulmonary veins bring blood from the lungs to the left atrium: o 2 from right lung; o 2 from left lung. 3. Other features: a. Note the presence of the ligamentum arteriosum, which is a remnant of the fetal ductus arteriosus. See Figure 15.13a, page 552. b. See also page 908. 15-6 CHAPTER 15: CARDIOVASCULAR SYSTEM: THE HEART II. STRUCTURE OF THE HEART G. Paths of Blood through the Heart and Lungs (Pulmonary Circuit) See Fig 15.10, page 550 and Fig 15.11, page 551. 1. right atrium (deoxygenated blood) (tricuspid valve) 2. right ventricle (pulmonary semi-lunar valve) 3. pulmonary trunk 4. pulmonary arteries 5. capillaries (alveoli) in lungs 6. pulmonary veins 7. left atrium (bicuspid or Mitral valve) 8. left ventricle (aortic semi-lunar valve) 9. ascending aorta * Note how the ascending aorta arches over the pulmonary trunk and heads downward forming the thoracic aorta and abdominal aorta. 15-7 CHAPTER 15: CARDIOVASCULAR SYSTEM: THE HEART II. STRUCTURE OF THE HEART H. Blood Supply to the Heart: Coronary Circulation (i.e. Pathway through Myocardium or how the heart muscle itself is supplied with blood). See Fig 15.15, page 553. 1. ascending aorta (oxygenated blood) 2. coronary arteries (1st and 2nd branch of aorta) a. left coronary artery b. right coronary artery * Definition: Anastomoses = connections between 2 or more branches of arteries that supply the same region with blood. o provide alternate routes for blood to reach a particular region; o many in heart. 3. capillaries in myocardium (exchange of gases) 4. cardiac veins (deoxygenated blood) a. great cardiac vein; b. middle cardiac vein. 5. coronary sinus 6. right atrium 15-8 CHAPTER 15: CARDIOVASCULAR SYSTEM: THE HEART II. STRUCTURE OF THE HEART I. Summary of Pulmonary, Coronary and General Systemic Circulations 15-9 CHAPTER 15: CARDIOVASCULAR SYSTEM: THE HEART III. Angina Pectoris and Myocardial Infarction (MI) See blue box on page 551 and introduction on page 542. Blood clots, fatty atherosclerotic plaques, and smooth muscle spasms within the coronary vessels lead to most heart problems. A. Definitions: 1. Ischemia = reduction of blood flow; 2. Hypoxia = reduced oxygen supply due to ischemia; 3. Angina pectoris ("strangled chest") = severe pain that accompanies myocardial ischemia. a. crushing chest pain radiating down left arm; b. labored breathing, weakness, dizziness, perspiration; c. occurs during exertion, fades with rest; d. relieved by nitroglycerin. 4. Myocardial Infarction (MI) = "heart attack". a. death of portion of myocardium; b. caused by a thrombus (stationary blood clot) or embolus (moving blood clot) in a coronary artery; c. may cause sudden death if conduction system is disrupted (see below) and ventricular fibrillation occurs; d. treatments include clot-dissolving agents (i.e. TPA and streptokinase), along with heparin or angioplasty. 5. Reperfusion Damage occurs when an oxygen deprived (hypoxic) tissue's blood supply is reestablished. a. due to formation of oxygen free radicals; b. damage to enzymes, neurotransmitters, nucleic acids and phospholipids; c. implicated in a number of diseases including heart disease, Alzheimer's, Parkinson's, cataracts, and rheumatoid arthritis and contributes to aging; d. Anti-oxidants defend the body against this damage and include the enzyme catalase, Vitamin E, C, and beta-carotene. 15-10 CHAPTER 15: CARDIOVASCULAR SYSTEM: HEART ACTIONS I. CARDIAC CYCLE A. Introduction 1. includes all of the events associated with one heartbeat; 2. The atria and ventricles alternately contract and relax (i.e. when the two atria contract, the two ventricles relax and vice versa). 3. Blood flows from areas of high pressure to areas of low pressure. As a chamber of the heart contracts, pressure increases, while as a chamber relaxes, pressure decreases. 4. Definitions: See Fig 15.16, page 554. a. Systole = phase of contraction; b. Diastole = phase of relaxation. 5. A complete cardiac cycle includes systole and diastole of both atria, and systole and diastole of both ventricles. B. General Summary of Cardiac Cycle (Keyed on at the end of this outline) Phase VENTRICULAR ATRIAL VENTRICULAR ATRIAL CONTRACTION RELAXATION RELAXATION CONTRACTION (SYSTOLE) (diastole) (DIASTOLE) (systole) Blood Flow Valves pressure 15-11 CHAPTER 15: CARDIOVASCULAR SYSTEM: HEART ACTIONS I. CARDIAC CYCLE C. Specific Phases of the Cardiac Cycle: Fig 15.17, page 555 shows the relation between the heart's ECG and mechanical events (contraction and relaxation), and the consequent changes in atrial pressure, ventricular pressure, ventricular volume, and aortic pressure during the cardiac cycle. 1. Relaxation (Quiescent) Period (Early ventricular diastole) a. follows T-wave; b. Ventricular pressure drops; c. SL valves close; d. isovolumetric relaxation for brief time; e. When ventricular pressure drops below atrial pressure, AV valves open; f. 0.4 seconds. 2. Ventricular Filling (Mid to Late ventricular Diastole) a. Rapid ventricular filling occurs just after AV valves open (remember atria had filled during ventricular contraction); b. SA Node fires (P wave), atria contract, and remainder of ventricular filling occurs; c. ventricles have completed filling = end-diastolic volume c. Atria relax, ventricles depolarize (QRS complex). d. 0.1 seconds. 3. Ventricular Systole a. Impulse passes through AV Node and then through ventricles; b. Ventricles contract; c. Ventricular pressure increases rapidly; d. AV valve close: o Isovolumetric Contraction Phase (constant volume) = start of contraction to opening of SL valves = 0.05 sec; o Ventricular Ejection Phase = opening of SL valves to closing of SL valves; o End-systolic volume reached when ventricle finish emptying e. 0.3 seconds. * Stroke Volume = End-diastolic volume minus end-systolic volume 15-12 CHAPTER 15: CARDIOVASCULAR SYSTEM: HEART ACTIONS II. HEART SOUNDS (lub-dup) See Fig 15.18, page 557. A. Introduction These sounds can be heard through a physician's stethoscope. They represent the closing of heart valves, and therefore help in diagnosing any problems occurring in the valves. B. Sounds 1. lub = closing of AV valves (ventricular systole); loud and long. 2. dup: closing of SL valves (ventricular diastole); short and sharp. C. Significance If the closing of the valve cusps is incomplete, some blood may leak back = murmur. III. CARDIAC MUSCLE FIBERS A. Review the differential ion concentrations that maintain a cell's Resting Membrane Potential (RMP): B. Physiology of Contraction 1. Rapid depolarization due to opening of Na+ channels: a. Contractile fibers of the heart have a resting potential of -90mV; b. When the potential is brought to -70mV by excitation of neighboring fibers, certain sodium (Na+) channels open very rapidly; c. Na+ ions rush into the cytosol of fibers and produce a rapid depolarization. 2. Plateau due to opening of Ca++ channels a. Ca++ channels open; b. Ca++ ions enter cytosol of fibers from ECF; c. Ca++ ions pour out of SR into cytosol; d. Depolarization is maintained for 0.25 seconds (250msec). e. Ca++ binds troponin ... contraction. Note that epinephrine increases contraction force by increasing Ca++ influx, and drugs called calcium channels blockers (i.e. verapamil) reduce Ca++ inflow and therefore diminish the strength of a heartbeat. 15-13 CHAPTER 15: CARDIOVASCULAR SYSTEM: HEART ACTIONS III. CARDIAC MUSCLE FIBERS B. Physiology of Contraction 3. Repolarization due to opening of K+ channels a. K+ channels open; b. K+ ions diffuse out of fibers; c. Na+ and Ca++ channels close; d. -90mV resting potential is restored. * Refractory Period = the time following a contraction when a second contraction cannot be triggered. a. longer than contraction itself; b. necessary for ventricles to relax and fill with blood before again contracting to eject the blood. 4. Strength of Contraction a. Within physiologic limits increased stretch of cardiac muscle fiber will increase the strength of contraction b. Caused because cardiac muscle is at less than optimal length when the heart is at resting rate c. The Frank-Starling Law of the Heart says that strength (and therefore stroke volume) increases as venous return (preload) increases d. Basically this means that as blood flows into the heart, it must be pumped out IV. Cardiac Conduction System (CCS) There are specialized areas of cardiac muscle tissue (1%) in the heart that are autorhythmic (self-exciting). These cells compose the CCS and are responsible for initiating and distributing cardiac (electrical) impulses throughout the heart muscle (i.e. cause the heart to beat). These specialized areas together coordinate the events of the cardiac cycle, which makes the heart an effective pump. A. Components of CCS: See Fig 15.19 and Fig 15.20, page 558. 1. Sinoatrial Node (S-A Node): a. located in right uppermost atrial wall; b. PACEMAKER = self-exciting tissue (rhythmically and repeatedly [60-100 per minute] initiates cardiac impulses); c. Impulse travels throughout atrial fibers via gap junctions in intercalated discs to the... 15-14 CHAPTER 15: CARDIOVASCULAR SYSTEM: HEART ACTIONS IV. Cardiac Conduction System (CCS) A. Components of CCS: 2. Atrioventricular Node (A-V Node): a. located in interatrial septum; b. serves as a delay signal that allows for ventricular filling; c. Cardiac impulse then enters the... 3. Atrioventricular (AV) Bundle (Bundle of His): a. only electrical connection between the atria and ventricles; b. located in the superior interventricular septum; c. Impulse enters both ... 4. Right and left bundle branches a. lead downward through interventricular septum toward apex, and impulse finally reaches... 5. Purkinje Fibers (Conduction Myofibers) a. large diameter conduction myofibers; b. located within the papillary muscles of the ventricles; c. conduct the impulse into the mass of ventricular muscle tissue. d. cause ventricles to contract which forces blood out. B. Summary Table of CCS (Keyed at the end of this outline) CCS LOCATION SIGNIFICANCE SENDS CARDIAC COMPONENT IMPULSE TO ... 15-15 CHAPTER 15: CARDIOVASCULAR SYSTEM: HEART ACTIONS V. ELECTROCARDIOGRAM (ECG) See Fig 15.22, page 559. A. Definition ECG = a recording of the electrical changes that occur in the myocardium during the cardiac cycle (see below); B. Instrument used to record an ECG = electrocardiograph; C. used to determine if: 1. the conduction pathway is normal; 2. the heart is enlarged; 3. certain regions are damaged. D. Rules to remember: 1. Depolarization precedes contraction; 2. Repolarization precedes relaxation. E. Three waves per heartbeat: 1. P wave is a small upward wave. a. represents atrial depolarization (spreads from SA node throughout both atria); b. 0.1 sec after P wave begins, atria contract. 2. QRS Complex a. begins as a downward deflection; continues as large, upright, triangular wave; ends as a downward wave; b. represents onset of ventricular depolarization (spreads throughout ventricles); c. shortly after QRS begins, ventricles start to contract. 3. T wave a. dome-shaped, upward deflection; b. represents ventricular repolarization; c. occurs just before ventricles start to relax; d. shape indicates slow process. * P-Q Interval and S-T segment F. Abnormal ECG's: See Fig 15.23, page 560. 1. enlarged P = enlargement of an atrium possibly due to mitral stenosis; 2. enlarged Q wave = MI; 3. enlarged R wave = ventricular hypertrophy. 15-16 CHAPTER 15: CARDIOVASCULAR SYSTEM: HEART ACTIONS VI. CARDIAC OUTPUT (CO) A. Definition CO = the volume of blood pumped by each ventricle in one minute; B. CO = heart rate (HR) x stroke volume (SV) C. SV = volume of blood pumped out by a ventricle with each beat; D. Normal CO = 5 liters. VII. Regulation of Cardiac Cycle / Heart Rate A. Autonomic Nervous System: See Fig 15.24, page 561. Recall that cardiovascular center is located in medulla of brainstem. 1. parasympathetic (normal) decreases; cardioinhibitor reflex center 2. sympathetic (stress) increases; cardioacceleratory reflex center B. Chemicals 1. hormones (i.e. epinephrine increases); 2. ions a. calcium increases; b. potassium and sodium decreases. C. Age (decreases) D. Sex 1. females increased; 2. males decreased. E. Temperature F. Emotion G. Disease 15-17 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS I. INTRODUCTION The blood vessels form a closed system of tubes that carry blood away from the heart, transport it to all the body tissues and then returns it to the heart. Hemodynamics is the study of the forces involved in accomplishing that feat. II. TYPES OF BLOOD VESSELS: A. Arteries carry blood away from the heart. See Fig 15.25a, page 565 and Fig 15.32, page 569. 1. strong and thick-walled vessels; 2. walls have three distinct layers: a. tunica interna (intima) surrounds lumen and is composed of: a layer of endothelium (simple squamous epithelium), a basement membrane, an internal elastic lamina. b. tunica media is the thickest layer composed of: smooth muscle cells; elastic fibers. c. tunica externa (adventitia) is the outermost layer composed of elastic fibers collagen fibers. 3. carry blood that is under great pressure. 4. carry blood that is high in oxygen and low in carbon dioxide, except the pulmonary arteries; 5. branch and give rise to thinner vessels called arterioles. 6. may unite with branches of other arteries supplying the same region forming anastomoses (i.e. providing alternate routes). 15-18 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS II. TYPES OF BLOOD VESSELS: B. Arterioles See Fig 15.26 and Fig 15.27, page 565. 1. very small arteries; 2. deliver blood to capillaries in tissues; 3. play a major role in regulating blood flow to capillaries, and therefore regulate blood pressure: a. Vasoconstriction (contraction) = decrease vessel volume = decreased blood flow = increased blood pressure. b. Vasodilation = increases vessel volume = increased blood flow = decreased blood pressure. * This will be discussed in greater detail later. C. Capillaries are the smallest, thinnest blood vessels. See Fig 15.29 and 15.30, page 567. 1. permit the exchange of gases, nutrients and wastes between blood and tissues; 2. connect arterioles to venules; 3. are composed of only a single layer of endothelium and basement membrane. 4. three types: based on structure and permeability a. continuous capillary = the plasma membranes form a continuous, uninterrupted ring around the lumen; found in skeletal, smooth muscle, CT's and lungs. b. fenestrated capillary = the endothelial plasma membranes contain pores (holes); found in the glomeruli of kidneys and villi of small intestine. c. sinusoids = contain spaces between the endothelial cells with basement membranes being incomplete or absent; found in liver and spleen. 5. Capillary Arrangement varies by tissue supplied a. Higher cellular needs (brain, muscle) = more elaborate network b. Lower cellular needs = less branching 6. Regulation of Capillary Blood Flow a. Smooth muscles control blood entry into capillary beds b. Metabolic need controls precapillary sphincter 15-19 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS II. TYPES OF BLOOD VESSELS: D. Capillary Exchange: See Fig 15.31, page 568. Gases, nutrients, and wastes are exchanged between blood in capillaries and tissues in three ways: 1. diffusion a. most common; b. substances include oxygen, CO2, glucose, & hormones, c. Lipid-soluble substances pass directly through endothelial cell membrane; d. Water-soluble substances must pass through fenestrations or gaps between endothelial cells. 2. vesicular transport (endo/exocytosis); 3. bulk flow (filtration and absorption). a. filtration o hydrostatic (blood) pressure pushes small solutes and fluid out of capillary o colloid osmotic pressure (osmosis) draws fluid back into capillary o net affect is fluid loss at the beginning of capillary bed but most is regained by the end of the capillary bed o fluid not regained enters lymphatic vessels (next chapter) o a special situation occurs in the kidney (Chapter 20) E. Venules and Veins 1. Venules and Veins carry blood toward the heart; 2. Venules extend from capillaries and merge together to form veins; 3. thin-walled vessels with 3 tunics: Fig 15.25b, page 565 and 15.32, page 569: a. tunica intima = endothelium and basement membrane; b. tunica media = thin layer of smooth muscle; much thinner than artery; c. tunica externa = elastic and collagen fibers. See Fig 15.25a & b, page 565 and Fig 15.32, page 569 to compare the structure of a vein with an artery. 4. carry blood under low pressure; 15-20 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS II. TYPES OF BLOOD VESSELS: E. Venules and Veins 5. contain valves; See Fig 15.33, page 569. 6. carry blood that is high in carbon dioxide and low in oxygen, except the pulmonary veins. 7. Veins are large and therefore serve as a blood reservoir, especially in the skin F. Blood Distribution throughout Body: See Fig 15.34, page 570. 1. 60-70% in systemic veins and venules; 2. 10-12% in systemic arteries and arterioles; 3. 10-12% in pulmonary vessels; 4. 8-11% in heart; 5. 4-5% in systemic capillaries. * See Table 15.3, page 570 for a summary of blood vessel structure and function. G. Major Blood Vessel Summary Table (Keyed at the end of this outline) Type of Blood Vessel Function (i.e. direction of blood flow in terms of heart) Wall structure (layers and layer components) Concentration of gases (oxygen and carbon dioxide) N/A Pressure of blood carried N/A 15-21 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS III. HEMODYNAMICS: THE PHYSIOLOGY OF CIRCULATION A. Blood Pressure: 1. Definition: Blood pressure = the pressure exerted by blood on the wall of blood vessel. 2. Definition: Pulse = the pressure wave that travels through arteries following left ventricular systole. a. strongest in arteries closest to heart; b. commonly measured in radial artery at wrist; c. Normal pulse = 70-80 bpm; o tachycardia > 100 bpm; o bradycardia < 60 bpm. 3. Measuring BP: See Clinical Application 15.3, page 572-573. a. Instrument used is called a sphygmomanometer ; b. Brachial artery is typically used; c. Procedure will be addressed in laboratory. B. Arteries 2. In clinical use, we most commonly refer to arterial blood pressure , because the blood pressure in the veins is essentially insignificant. 3. The arterial blood pressure rises to its maximum during systole (contraction) and falls to its lowest during diastole (relaxation). 4. In a normal adult at rest, the BP = 120 mm Hg/ 80 mm Hg. C. Arterial Blood Pressure See Fig 15.36, page 573. 1. Heart Action (cardiac output): a. CO is the volume of blood pumped by each ventricle each minute; o the volume of blood that is circulating through the systemic (or pulmonary) circuit per minute; o 5 liters/minute is normal adult. b. CO is affected by: o stroke volume (SV); o heart rate (HR); (Remember that CO = HR X SV); 2. Blood Volume (increase in blood volume increases BP) See Fig 15.39, page 576. a. Normally fairly constant 15-22 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS III. HEMODYNAMICS: THE PHYSIOLOGY OF CIRCULATION C. Arterial Blood Pressure 3. Peripheral Resistance (R = opposition to blood flow usually due to friction) a. Resistance is the opposition to blood flow primarily due to friction. This friction depends on three things: o Blood viscosity ( viscosity: R: bp) normally constant direct relationship o Total blood vessel length ( blood vessel length: R: bp) normally constant direct relationship o Blood Vessel Radius ( radius: R: bp). MOST significant factor in determining Blood Pressure Indirect relationship D. Control of Blood Pressure: 1. BP = CO X PR a. altering CO or PR alter BP directly b. to alter CO either HR or SV (therefore blood volume) can be used c. to alter PR either viscosity, vessel length, or vessel radius can be used d. in total any one ore combination of HR, SV or PR is used to alter BP e. Mechanical, neural, and chemical (hormone) factors affect SV and HR f. Neural and hormonal controls are used for PR 2. Mechanical Factors Affecting Blood Pressure a. Venous return (preload) o heart can only pump the blood that is returned to it o increased preload increases the stretch of cardiac muscle fibers o The Frank-Starling Law of the Heart says that strength (and therefore stroke volume) increases as venous return (preload) increases o Basically this means that as blood flows into the heart, it must be pumped out 15-23 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS III. HEMODYNAMICS: THE PHYSIOLOGY OF CIRCULATION D. Control of Blood Pressure: 3. Neural Regulation: See Fig 15.24, page 561. a. The cardiovascular (CV) center and vasomotor center are located in the medulla of the brain stem. b. Input to centers: Nerve impulses are sent to the centers from three areas: 1. Higher brain centers; 2. Baroreceptors (or pressoreceptors) that detect changes in BP in aorta and carotid arteries; 3. Chemoreceptors that detect changes in key blood chemical concentrations (H+, CO2, and O2). c. Center Output: 1. Nerve impulses are sent from the CV center to the SA Node of heart; 2. Nerve impulses are sent from the vasomotor center to the smooth muscle of peripheral blood vessels (i.e. arterioles). d. Negative-Feedback Regulation: See Figures 15.39, page 576 and 15.40, page 577. 1. If BP is too high: o BP increase is detected by baroreceptors in the carotid a. or aorta; o They send an impulse to CV and vasomotor centers; o The CV center interprets that message and sends a signal to the SA Node which decreases heart rate, lowering CO and bp; o The vasomotor center sends an impulse to the peripheral arterioles causing vasodilation, which lowers bp. 2. If BP is too low... o exact opposite of above o plus hormonal response 15-24 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS III. HEMODYNAMICS: THE PHYSIOLOGY OF CIRCULATION D. Control of Blood Pressure: 4. Hormonal Control Several hormones affect BP by acting on the heart, altering blood vessel diameter, or adjusting blood volume. a. Hormones that increase BP: o Epinephrine and norepinephrine * increases CO (rate & force of contraction) and causes vasoconstriction of arterioles. o Antidiuretic hormone (ADH) * increases reabsorption of water by the kidneys (DCT), and causes vasoconstriction of arterioles during diuresis and during hemorrhage. o Angiotensin II * has four different targets that cause vasoconstriction of arterioles and causes the secretion of aldosterone (discussed in greater detail in Chapter 20). o Aldosterone * increases Na+ and water reabsorption in the kidneys (PCT). b. Hormones that decrease BP: o Atrial natriuretic peptide (ANP) * causes vasodilation of arterioles and promotes the loss of salt and water in urine. See blue box on page 546. o Histamine * causes vasodilation of arterioles (plays a key role in inflammation). 15-25 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS III. HEMODYNAMICS: THE PHYSIOLOGY OF CIRCULATION E. Venous Blood Flow 1. Very low pressure 2. Flow is assisted by skeletal muscle contractions squeezing veins 3. Blood can only flow one directions (toward heart) because of valves 4. Respiratory movements also assist by varying intrathoracic pressure causing pumping action F. Central Venous Pressure 1. The pressure of blood in right atrium 2. If the heart is weak blood remains in the right atrium after systole, causing increased pressure 3. This leads to backing up of blood in right atrium (congestive heart failure) 4. Normal heart action keeps central venous pressure near 0 (zero). IV. PATHS OF CIRCULATION: A. Pulmonary Circuit = the vessels that carry blood from the right ventricle to the lungs, and the vessels that return the blood to the left atrium: See Fig 15.42, page 581. 1. pulmonary trunk 2. right and left pulmonary arteries (deoxygenated blood) 3. capillaries in lungs 4. right and left pulmonary veins (oxygenated blood) 15-26 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS IV. PATHS OF CIRCULATION: B. Systemic Circuit = the vessels that carry blood from the heart to body cells and back to the heart. 1. Arterial System: See Fig 15.53, page 592 for general overview. a. The aorta is divided into the following regions: o ascending aorta; o aortic arch; o thoracic aorta; o abdominal aorta; * The abdominal aorta terminates at the brim of the pelvis and branches into each leg = common iliac arteries. b. Principal Branches of the Aorta There are many arteries that branch from these regions of the aorta and supply blood to many areas of the body. The arteries you will need to know are listed below, and the body part they supply with blood, follows in parentheses: Branches of the ascending aorta: 1. right coronary a. (myocardium); 2. left coronary a. (myocardium). Branches of the aortic arch: See Fig 15.44, page 583. 1. brachiocephalic a. (right side of head and right arm): Fig 15.49, a. right subclavian a. (right arm): page 587. o vertebral a. (cervical vertebrae/skull) Fig 15.46, pg 585. 1. basilar a. (brain) Fig 15.48, page 586. a. Circle of Willis (brain) o axillary a. (armpit) 1. brachial a. (upper arm) a. radial a. (lateral forearm); b. ulnar a. (medial forearm) palmar arches (palm) 1. digital a. (fingers) 15-27 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS IV. PATHS OF CIRCULATION: B. Systemic Circuit 1. Arterial System: Branches of the aortic arch: 1. brachiocephalic a b. right common carotid a. (right side of head) external carotid a. (scalp) internal carotid a. (brain) 2. left common carotid artery (left side of head): a. external carotid a. b. internal carotid a. 3. left subclavian artery (left arm): Branches follow same pattern as right subclavian artery Branches of thoracic aorta: 1. intercostals (intercostal/chest muscles); 2. superior phrenics (superior diaphragm); 3. bronchial arteries (bronchi of lungs); 4. esophageal arteries (esophagus). Branches of abdominal aorta: See Fig 15.45a&b, pg 584. 1. inferior phrenics (inferior diaphragm); 2. celiac trunk (artery): a. common hepatic a. (liver); b. left gastric a. (left stomach); c. splenic artery (spleen); 3. superior mesenteric (small intestine, cecum, ascending/transverse colon, pancreas); 4. suprarenals (adrenals); 5. renal arteries (kidneys); 6. gonadal arteries (ovarian/testicular); 7. inferior mesenteric (descending/sigmoid colon, rectum). Branches of Common Iliac Arteries (right and left): See Fig 15.52, page 590. 1. external iliac a. (lower extremities) a. femoral a. (thigh) popliteal a. (knee region) 1. posterior tibial a. (lower leg) a. plantar arteries (heel, foot, and toes). 2. anterior tibial a. a. dorsalis pedis a. (foot and toes). 15-28 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS IV. PATHS OF CIRCULATION: B. Systemic Circuit 2. Venous System: See Overview Figure 15.60, page 597. Veins, that return blood to the heart after gas, nutrient, and waste exchange, usually follow pathways that are parallel to the arteries that supplied that particular region with blood. The veins you'll need to learn are identical to the arterial list with the following exceptions: a. jugular veins (head); See Fig 15.54, page 593. o external jugular vein (face and scalp); o internal jugular vein (brain). b. median cubital vein (venipuncture site): Fig 15.55, pg 593. c. Note that there are 2 brachiocephalic veins. The union of the subclavian and jugular veins on each side forms them. See Fig 15.56, page 594. d. Superior Vena Cava (formed by the union of the left and right brachiocephalic veins = head and upper limbs). f. coronary sinus (cardiac veins); o cardiac veins (caps of myocardium). g. hepatic vein (drains hepatic portal system):See Fig 15.57, page 594. o hepatic portal vein (drains gastric, mesenteric and splenic veins); 1. gastric vein (stomach); 2. mesenteric veins (intestines); 3. splenic vein (spleen); * These veins do not drain directly into the inferior vena cava. Instead, the blood drained from these abdominal organs travels to the liver via the portal vein. Recall the hepatic portal system discussed during digestion. h. great saphenous vein = the longest vein in the body. Extends from the medial ankle to the external iliac vein. See Fig 15.59, page 596. j. Inferior Vena Cava (drains veins from abdominal & lower limbs). i. Azygous System – azygous vein (right) and hemiazygous (left) o drain intercostal veins and lumbar veins 15-29 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS IV. PATHS OF CIRCULATION: C. Tracing Blood flow 1. From right fingers to left ear: right finger capillaries to right digital veins to right venous palmar arches to right radial or ulnar vein to right brachial vein to right axillary vein to right subclavian vein to right brachiocephalic vein to superior vena cava to right atrium... left ventricle to aorta (ascending and arch) to left common carotid artery to left external carotid artery to left ear capillaries. Could the above tracing have been different at any points? 2. From the stomach to the left fingers. 3. From the right toe to the left kidney. 4. From the right kidney to the ride side of brain. 15-30 CHAPTER 15: CARDIOVASCULAR SYSTEM: BLOOD VESSELS V. LIFE SPAN CHANGES A. Cholesterol deposits in arteries as one ages. 1. Accumulation causes hypertension and cardiac disease (see below). B. Cardiac cells are replaced by fibrous connective tissue and fat as one ages. C. Blood pressure increases with age, while resting heart rate decreases. D. Moderate exercise correlates to lowered risk of heart diseases in the elderly. VI. Disorders/Homeostatic Imbalances of the Cardiovascular System: A. Implantable Defibrillator. See introduction on page 542. B. Pericarditis. See beige box on page 543. C. Mitral Valve Prolapse. See beige box on page 546. D. Angina Pectoris and Myocardial Infarction. See beige box on page 551. E. Familial Amyloidosis. See beige box on page 558. F. Arrhythmias. See Clinical Application 15.1, pages 562-563. G. Abnormal Calcium or Potassium Levels. See beige box on page 561. H. Blood Vessel Disorders. See Clinical Application 15.2, pages 571. I. Hypertension. See Clinical Application 15.5, page 578. J. Cardiac Tamponade. See beige box on page 579. K. Pulmonary Edema. See beige box on page 581. L. Molecular Causes of Cardiovascular Disease. See Clinical Application 15.7, pages 598 and 599. M. Coronary Artery Disease (CAD). See Clinical Application 15.8, page 600. VII. Other Interesting Applications Concerning the CV System A. Heart Transplantation. See Clinical Application 15.1, page 556. B. Space Medicine. See Clinical Application 15.4, page 574. C. Exercise and the CV System. See Clinical Application 15.6, page 580. VIII. Clinical Terms Related to the Cardiovascular System. See page 601. IX. Innerconnections of the Cardiovascular System. See page 602. 15-31 CHAPTER 15: CARDIOVASCULAR SYSTEM Summary Table of CCS CCS LOCATION SIGNIFICANCE SENDS CARDIAC COMPONENT IMPULSE TO ... Sinoatrial Node right uppermost Pacemaker; initiates Atrioventricular atrial wall cardiac impulse 60- Node 100 times per minute Atrioventricular interatrial septum delay signal to allow Atrioventricular Node for ventricular filling Bundle Atrioventricular superior only electrical right and left bundle Bundle interventricular junction between branches septum atria & ventricles right and left bundle lateral passes signals down Purkinje fibers branches interventricular to apex septum Purkinje fibers in papillary muscles conduct impulse to of ventricles the mass of ventricular N/A myocardium and forces blood out General Summary of Cardiac Cycle Phase VENTRICULAR ATRIAL VENTRICULAR ATRIAL CONTRACTION RELAXATION RELAXATION CONTRACTION (SYSTOLE) (diastole) (DIASTOLE) (systole) Blood Blood is forced Atria fill with Ventricles fill with Blood is forced flow from ventricles blood. blood. from atria into into arteries. ventricles. Valves SL open SL open AV open AV open AV closed AV closed SL closed SL closed Pressure V high A low but rises V low but rises as A high as filling filling continues continues 15-32 CHAPTER 15: CARDIOVASCULAR SYSTEM Major Blood Vessel Summary Table Type of Blood Arteries Veins Capillaries Vessel Function (i.e. carry blood away from carry blood toward exchange site for direction of blood heart heart gases, nutrients & flow in terms of wastes between heart) blood and tissues; connect arterioles and venules. Wall structure three tunics: same three tunics only tunica intima (layers and layer innermost = tunica as arteries but (single layer of components) intima (endothelium plus tunica media is endothelium plus basement membrane); much thinner; its basement middle = tunica media equipped with membrane) (thick smooth muscle valves plus elastic fibers); outermost = tunica adventitia (collagen and elastic fibers) Concentration of high in oxygen; high in carbon gases (oxygen and low in carbon dioxide, dioxide; low in carbon dioxide) except pulmonary oxygen, except N/A arteries pulmonary veins Pressure of blood high low so they are carried equipped with valves N/A 15-33


text:
The New York Giants have finalized their 53 man roster per the league-wide deadline at 9:00 pm ET. Earlier in the morning they made 15 roster moves and still had seven to make before they got down to the league maximum. A couple of interesting but not too terribly surprising cuts the Giants made earlier in the day were Greg Jones and running back D.J. Ware
Jones was a sixth round pick in 2011, but what makes it even more surprising was the fact that he played in all 16 games last season and even started five. His release likely had quite a bit to do with injuries to other positions, and the fact that the Giants are carrying five defensive ends.
The Giants also brought in Keith Rivers this offseason–who by all accounts–is taking Jones' spot as a backup outside linebacker, but will see his share of time on the field.
Ware getting cut was not as much of a surprise as Jones, but a lot of people thought Ware still had a chance to make the team based on his knowledge of the offense and pass blocking ability. Clearly the Giants felt Andre Brown and Da'Rel Scott offered more upside, which I agree with. Ware has hit his ceiling, and he wasn't getting any better.
Some of the big news updates from tonight are the Giants putting Terrell Thomas and Shaun Rogers on season ending injured reserve. Thomas was expected to be able to play this season, but it looks like that won't be happening.
The final five players cut were Ryan Perrilloux, Dante Hughes, Chris White, Steven Goodwin and Laron Scott, all players who did not figure to make the roster.
You can also bet the Giants are not done making moves. They will most likely use that new IR rule on one of several players to choose from, and Adam Schefter seems to think the Giants are in the market for an offensive lineman.
[blackbirdpie url="https://twitter.com/AdamSchefter/status/241555272160665601"]
So don't expect the Giants to be quiet over the weekend. Check back here for updates on any potential rumors or updates!
Jeff is an NFL Featured Columnist for RantSports.com. He contributes mainly to the New York Giants and NFL Rumors pages. He also will occasionally touch on the NBA and humorous videos involving all sports. Check back to Rant Sports for more NFL roster cuts!
Follow Jeff on Twitter @Jeff_Shull


text:
Unterkunft Thailand Bangkok Refill Now
Fotos Ausstattung Karte Streetview Testberichte
Located in a brand-new building in a vibrant and friendly neighborhood, REFILL NOW! is the perfect choice for those seeking a one-of-its-kind experience.
At affordable prices REFILL NOW! has it all: clean rooms, hot water, friendly and knowledgeable staff, extensive amenities, including a coffee shop, restaurant, laundry and Internet services.
Its contemporary look, with ground-to-roof glass fronts surrounding all sides of the four-story building ,and a lush garden area create a spacious, bright and natural feel.
Design and layout cleverly merge to evoke a coexisting sense of privacy and openness. Retreat or reunite.
At REFILL NOW!, it's all about choice. Relax, rejuvenate and replenish.
All of our living quarters are modern and air-conditioned (6pm to 8am). Due to REFILL NOW! being an all-glass-building, every room is bright and flooded with plenty of natural daylight. Each room comes with its own theme.
Here, at REFILL NOW! there are no dingy, dark rooms, but only airy and open space.
Our modern and playful furniture was purpose designed, and selected with best of comfort and a sense of humor in mind. We provide secure lockers, spacious enough to fit a backpacker's belongings, while our shared atmospheric bathrooms feature special effects.
No need to worry about bed linen or towels; what we supply is five-star hotel quality!
REFILL NOW! offers six-sleeper dorms with three bunker beds each. To socialize or connect, soft screens separating the bed units can be opened, while for extra privacy, they may be closed.
Haben Sie hier übernachtet? Einen Testbericht verfassen
Notiz: Es ist die Verantwortung der Hotelkette und/oder der individuellen Unterkunft für die Richtigkeit der angezeigten Bilder zu sorgen. Travellerspoint ist nicht verantwortlich für Unstimmigkeiten auf den Fotos.


text:
Uh Oh. Something is missing. Try double checking things.
Posts Tagged: Clearbridge Nanomedics
Tech In Asia Online Community
Follow @TechinAsia
Featured Posts
Trending Posts
- Instagram appears to be blocked in Pakistan, uproar hits Twitter
- Xiaomi officially launches in Indonesia with Redmi 1S
- Chinese social network for following celebs – or even becoming one – secures $6.5M funding
- Uber continues its China expansion as it launches in Hangzhou and Chengdu
- Blogapalooza is planting the seeds of a revolt against old media
- Indian price comparison site PriceBag raises $2M
- Singapore's HipVan raises $1.4M from LionRock Capital and Toivo Annus
- Tripvisto wants more Indonesians take on tours, gets seed funding from East Ventures
- Taiwan-based music streaming startup KKBox raises $104M from Singapore's GIC
- Gamified and social trading platform Ayondo gets $4M from Luminor Capital


text:
"In addition to the more traditional 'socially responsible investors," we are finding that some of our mainstream investors are now looking at sustainability performance as an indicator of overall business value. They're acting on the theory that our sustainability measures-our efficiency with resources, our employee retention, etc. –are predictors of overall business profitability."
Items tagged with sustainable innovations
Don't Just Recycle Electronics – Innovate!
Posted on Jul 15 2009 by Diana Rivenburgh
Jul 15 2009
A growing number of states are passing electronic recycling legislation that often requires manufacturers to fund recycling and collection for old personal computers, monitors and televisions. The Consumer Electronics Association (CEA), a trade group representing 2,000 electronics companies is negotiating with NYC officials to change an ordinance expected to go into effect on July 31, 2009 that would require door-to-door pick up and is estimated to cost the industry $200 million per year.


text:
ShopHappens.com is a website dedicated to sharing shopping knowledge with the general public. Customer service stories, awesome sales, interviews with Etsy sellers… nothing is off-limits as long as it is shopping related. If you have something to contribute, please let us know! We love guest bloggers and contributors!
About the Authors
Erin is an online shopper extraordinaire who has racked up enough experience to be considered an expert. As her friends started coming to her for advice, she thought that a website to share her shopping and customer service experience was a good idea. And so ShopHappens was born! In her spare time, Erin enjoys traveling, spending time with family and friends, and browsing the world wide web.You can find Erin on Twitter and Google+
Michelle – Michelle is one of Erin's first and most loyal friends. She is a trusted advisor when it comes to fashion advice and always knows about the most recent trends. Her style is best described as "a little bit of everything," and this makes her the perfect candidate for writing at ShopHappens! Michelle currently works at the Elizabeth Glaser Pediatric AIDS Foundation.
Callie – While Callie's identity remains generally anonymous, her personality shines through in every post she writes. Some of the most interesting things happen when Callie is in the room, and she has the true gift of being able to retell a story with animation and excitement. She's a wealth of knowledge when it comes to beauty secrets and always remembers to reward great service, which makes her an ideal ShopHappens contributor!
April – April is best known for her writing skills – she actually owns and operates another website AND still maintains a full-time job! This multi-talented lady is always going to share her opinion and provide solid arguments for why she feels that way, and we are so thankful that she has been an occasional reviewer here at ShopHappens!
Keep checking back for more! If you have any suggestions, comments, or concerns, please visit our Contact page.
- Custom Search
Popular Now
- Review: Jergens Natural Glow Express
- Giveaway: Custom Birthstone Necklace from Danique Jewelry!
- Item Review: Bloch Crystal Flats
- New Shoe Boutique: ShoeMint.com
- Calling all Educators: Check out these retailers for exclusive teacher discounts!
- Item Review: New Balance Rock and Tone Shoes
- Etsy Giveaway: Win a $25 Gift Card to Danique Jewelry!
- Item Review: Emu vs. Ugg
- Sale Alert: Tiffany & Co. at Modnique!
- Etsy Giveaway: Custom Initial Necklace from Olive Yew Jewels {CLOSED}
Savvy Shoppers
Catch up
- $500 Amazon Gift Card Giveaway from the Slice App!
- Giveaway: Custom Birthstone Necklace from Danique Jewelry!
- Shopping for a New Home: Tips and Tricks
- Etsy Spotlight: Michelle from fixations
- Calling all Educators: Check out these retailers for exclusive teacher discounts!
- Review: Beauty Without Cruelty Rosemary Mint Tea Tree Shampoo
- Happy New Year from ShopHappens
- Love Shopping Retail? Try Retale to save some extra dough


text:
Singer-actress Kamaliya, the wife of Kyiv Post publisher Mohammad Zahoor, gave birth on Sept. 6 to twin girls in Kyiv.
Zahoor, the former steel magnate who now owns valuable real estate, media and other holdings through his ISTIL Group, announced the births late last night in text and other messages to family, friends and associates.
The entrance to Kyiv's central registration office looks like a bizarre conveyor for production of newlyweds.
Apparently a certain Ukrainian boxing champion has warm feelings for a certain Hollywood actor-turned-politician.
It's wasn't a summer music festival or a beach party. Yet a crowd of scantily dressed people bearing nothing but bikinis and underwear gathered in Kyiv's Voskresenka neighborhood to shop.
The brain behind the "sextremist" FEMEN group, the topless women protesters who have gained international fame and scorn, turns out to be a man. At least that is the revelation made in a new documentary called "Ukraine Is Not A Brothel."
It is probably the last place where President Viktor Yanukovych expected dissent. His own Party of Regions appeared to develop a rift this week as several of its prominent members came out with public statements that they will not support European integration, which has become the mantra of both the authorities and the opposition on the eve of a potential signing of an Association Agreement with the European Union in November.
WBC heavyweight king Vitali Klitschko (45(41)-2) has sensationally opened the door to a mega-clash with British star David Haye and is reportedly in talks with the WBC to bypass mandatory Bermane Stiverne to make the lucrative fight with the Londoner in what would a huge final swan song for the champion who is set to retire from boxing next year.
Whatever readers think of Jaroslav Koshiw's latest book "Abuse of Power: Corruption in the office of the president," no one can accuse the Ukrainian-American author of shying away from powerful targets.
President Vladimir Putin's September 4th interview with Russian state broadcaster Channel One and the Associated Press cast a bright light on the incompetence of his public relations office and on his own antediluvian notions about Ukraine.
Whoever translated the official Kremlin transcript showed a striking ignorance of the English language—the translation is wooden—and of elementary political-historical terminology. Several sentences stand out, both because the translation is shockingly bad and because, when dissected, they reveal a great deal about Putin's mind-set.
Three Englishmen aged between 19 and 23 were hospitalized for head and arm injuries on the evening of Sept. 8 after a fight broke out involving nearly 40 English nationals and 21 Ukrainians in the outdoor terrace of Chateau cafe on Khreshchatyk Street, said the police and an eyewitness.
Kyiv Post publisher Mohammad Zahoor and his wife, Kamaliya, emerge from Isida Clinic, a maternity hospital in Kyiv, on Sept. 9 with their twin baby daughters, Arabella and Mirabella. Kamaliya gave birth on Sept. 6. Zahoor is a multimillionaire businessman whose ISTIL Group has media, real estate and other holdings. Kamaliya is a singer-actress with roles in four movies and several hit singles.
OKTYABRSK PORT, Ukraine — On Jan. 5, the Ocean Fortune, a 380-foot-long workhorse of the global arms trade, left this Black Sea port with unknown cargo concealed in its cavernous hold. The ship steamed south, slipped through the Bosporus Strait and turned toward the eastern Mediterranean. Then it disappeared.
It's not often that a multimillionaire moves into a president's backyard. But something along those lines is happening in Ukraine.
Vilnius - The foreign ministers of the European Union states who met on Saturday, Sept.7 have warned Russia that the country should not press on neighbors which are trying to have tighter relations with the West.
It was hard to believe one's eyes on Sept. 5 as Ukraine's parliament, notorious for brawls and squabbling, almost unanimously approved five bills required for signing the Association Agreement with the European Union this November.
When Kazakhstan joined the Russian-led Customs Union in 2010, it leaders were extremely upbeat about the prospects of this trade organization that also includes Belarus.
A familiar face will soon become President Viktor Yanukovych's new neighbor on the 138-hectare estate to which his residence is attached.
Red lights have been signalling for investors in Ukraine for some years now, a reflection of difficult fundamentals. Herein we would identify:
Berlin's Charite clinic is preparing a room for the treatment of Yulia Tymoshenko, Ukraine's jailed former prime minister, according to Deutsche Welle.
© 1995–2014 Public Media


text:
Home » Opinion » Columns
Betsy McCaughey: Ending the federal worker gravy train
Back in 1883, Congress passed the Pendleton Act to replace patronage with a federal civil service in which workers would be hired and paid based on merit.
The regional director overseeing the Pittsburgh VA collected a $63,000 award in 2012 shortly after six veterans treated there died needlessly from legionella, an infection traced directly to poor maintenance of the facility.
But merit no longer matters.
Take the Environmental Protection Agency worker making $125,000 a year who spent hours a day watching pornography.
The answer is that firing a federal worker is almost impossible, and making it stick, even less likely.
Incredibly, most federal departments have even laxer standards than the VA. Jeff Neely, the General Services Administration employee pictured in a hot tub sipping wine on taxpayer money, retired with benefits after the lavish 2010 Las Vegas boondoggle he attended was uncovered in the media. Two co-workers were fired but reinstated with back pay after appealing to the "merit" system's protection board, which protects everything but merit.
A worker with a high-school education earns 21 percent more working for the federal government than for a private employer, and gets 72 percent more in benefits. A worker with a bachelor's degree also makes out better with Uncle Sam, getting about the same wages as in the private sector but 46 percent more in benefits.
In addition, the federal workplace offers 10 paid holidays, plus 13 to 26 days annual vacation (depending on longevity) and up to 13 paid sick days a year.
That's easy street. Meanwhile, taxpayers are on the Road to Serfdom, working longer and paying more to support a government that does not serve them.
Betsy McCaughey is a former lt. governor of New York and author of Beating Obamacare 2014.
- Deroy Murdock: The indictment of Rick Perry is bizarre and unfounded - 0
- Another View - Marc Champion: A strong terror policy would cure Obama's golf woes - 0
- Jonah Goldberg: Obama confuses the TV world with the real one - 1
- George Will: In defense of the defenders - 0
- Roger Simon: Is Ferguson the future? - 0
- Charles Krauthammer: Stopping the worst people on earth - 0
- Lynn Preston's NH Legal Perspectives: What prospective real estate purchasers need to know - 0
- Gail Fisher's Dog Tracks: 'Mirror' approach reflects important role of humans in dog training - 0
- Thomas Sowell: The media and the mob - 1
Another View -- Frank Guinta: I am uniquely qualified to represent NH in CongressREADER COMMENTS: 9
- NH Motor Speedway to again host two Sprint Cup Series weekends in 2015 - 0
- St. Anselm football players practice ini August heat - 0
- White, Glenn lift Fisher Cats over Harrisburg, 6-4 - 0
- KSC field hockey first in coaches poll - 0
- New England Patriots guard Mankins traded to Tampa for TE Wright - 0
- NH Fisher Cat Lee still striving for making it to the major leagues - 0
- Former city restaurateur gets jail sentence for sex assault - 0
- Former high school art teacher gets suspended sentence in drug case - 0
- New Manchester school district standards to give teachers more leeway - 0
Boston Red Sox hammer Jays for seven runs in 11th, win 11-7READER COMMENTS: 0
Market Basket: 'So close, yet so far'
KSC field hockey first in coaches poll
Backyard boulder kills Raymond homeowner
Reports: Market Basket doomsday plan would shutter 61 of 71 stores if deal not struck soon
GOP for legal pot? Hemignway's high help
Ohio's Rob Portman: GOP can win back Senate


text:
Thank you for supporting Phil Ting for Mayor of San Francisco
Thank you for supporting Phil Ting for Mayor. Feel free to contact Phil directly at firstname.lastname@example.com or Joshua Abeyta at firstname.lastname@example.com if you'd like to learn more about how to get involved with his campaign.
Paid for by Phil Ting for Assembly 2012. FPPC ID# 1343137


text:
Sigh…no context, just a quick Associated Press gotcha blurb.
Yep, that reader's email to GetReligion pretty much sums up an atrocious, 135-word piece of AP "journalism" on Phil Robertson of "Duck Dynasty" fame.
The headline:
New anti-gay remarks by 'Duck Dynasty' star emerge
The lede:
NEW YORK (AP) — A&E has declined to comment on new video of "Duck Dynasty" star Phil Robertson reviving past anti-gay remarks.
His comments are included in a sermon delivered at his church in West Monroe, Louisiana, on Easter Sunday. Robertson includes homosexuals with other groups such as thieves and adulterers as hell-bound sinners.
What exactly did Robertson say? Did he quote the Bible inside a church (say, 1 Corinthians 6:9)? Why is it important for A&E — and not Robertson himself — to be contacted for comment?
AP provides no details at all.
Let's keep reading:
Robertson is the bearded patriarch of a clan that manufactures duck calls and became reality-TV stars. In December he set off a firestorm after GQ magazine quoted him linking homosexual behavior to bestiality.
Here is what GQ originally reported:
What, in your mind, is sinful?
"Start with homosexual behavior and just morph out from there. Bestiality, sleeping around with this woman and that woman and that woman and those men," he says. Then he paraphrases Corinthians: "Don't be deceived. Neither the adulterers, the idolaters, the male prostitutes, the homosexual offenders, the greedy, the drunkards, the slanderers, the swindlers—they won't inherit the kingdom of God. Don't deceive yourself. It's not right."
Is that linking homosexual behavior to bestiality?
More from AP:
He also made racist statements.
From the original GQ article: