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Business undergoes 'structural shift', as launch of Windows 8 fails to lift market while users choose not to replace older PCs. By Charles Arthur
A five-year lifespan turned out to be all that netbooks got. Acer and Asus are stopping manufacture from 1 January 2013 - ending what once looked like the future of computing. By Charles Arthur
Matthew Baxter-Reynolds: Microsoft's Surface is a post-PC tablet done right to compete effectively against the iPad. So why did 'tablets' on show at IFA 2012 look so much like adapted netbooks?
Smartphones outsold PCs and tablets combined, says research company – but netbooks have had their day as sales fall by 25% year-on-year. By Charles Arthur
US newspaper publisher makes massive investment in digital tools for its staff
Ask Jack: Su Butcher is thinking about buying a laptop for her seven-year-old son. She wants him to learn something, not just play games
Shipments drop by 11.4% in Western Europe as market underperforms, but Asus and Apple see benefits – though next two quarters expected to be tough as Thailand floods hit hard drive manufacture. By Charles Arthur
Much of our computing (including the storage of our personal data) is now being done remotely via something called the 'cloud'. John Naughton gives a brief history of how this radical shift came about, while Stuart Dredge assesses the relative merits of four cloud computing services
Tablet computers such as the iPad are now more popular in Western Europe than desktops, laptops and netbooks. By Josh Halliday
Ask Jack: David Peate and his wife want a simple, lightweight netbook for use on business trips, but would they be better off with one of the emerging class of mini-laptops?
Ask Jack: Paul O' Donovan is looking for netbook or slate computer with built-in GPS for off-shore navigation
What once seemed like the saviour of the industry has turned instead into a millstone for companies like Acer
Fourth-quarter figures show PC sales worldwide up 13.8%, but netbooks sliding as tablet sales eat into them. By Charles Arthur
Ask Jack: James A Schofield wants a netbook for travelling, but his need to run desktop PC software suggests a mini-notebook would be a better buy
There are bargains to be had for netbook shoppers on a budget, says Marc Lockley
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Please click on the link below: Registration Directions, Information and Forms (PDF)Reminder About Busing TimelinesNew registrations received and finalized by August 14, 2014 are assured bus assignments, presuming eligibility for busing, by the start of school. The SCESC, our transportation agency, will process busing applications for registrations after this date in accordance with the district's transportation guidelines for the start of school. Our goal is to insure every student registered before the start of school, who is eligible for busing, receives a bus assignment prior to start of school. However, for those who register after August 14, 2014 this may not be possible. Reminders for Completing Health Registration Requirements
Student Withdrawal/Transfer - Parental Sign Out Form*For students leaving the district*Download Student Transfer Form (PDF)

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New Stuff Tuesday
The hardest day of the week (Monday) is behind us. It's only looking up as we plug our way closer to the weekend! To help get you there, here's a list of NEW STUFF you can get today…..NEW STUFF TUESDAY! From books to DVD's….enjoy!
Allegiant by Veronica Roth
In a series that is comparable to 'The Hunger Games', the Veronica Roth trilogy ends with this book 'Allegiant'. What started with 'Divergent' and 'Insurgent', this story involves teenagers in a dystopian future world.
Sycamore Row by John Grisham
John Grisham's first and possibly most popular novel is 'A Time To Kill'. Grisham is giving readers a true sequel with this novel that takes readers back to that famous courthouse in Clanton. Jake Brigance finds himself in a controversial trial that will expose racial tensions and force Ford County to confront its tortured history.
The Conjuring
Based on a true story, The Conjuring tells the story of how paranormal investigators Ed and Lorraine Warren were called to help a family terrorized by a dark presence in a secluded farmhouse. Stars Vera Farmiga, Patrick Wilson, Ron Livingston and is Rated R.
The Way, Way Back
In this comedy, a lonely 14 year old boy is having a hard time fitting in, and finally finds his place in the world - all during a summer he will never forget. Stars Liam James, Toni Collette, Steve Carell and Sam Rockwell and is rated PG-13.
The Internship
This comedy has two salesmen trying to prove to the digital world that they are still needed by managing to land an internship at Google. Stars Vince Vaughn, Owen Wilson, Rose Byrne and Max Minghella. Rated PG-13
Before Midnight
We meet Jesse and Celine and almost two decades have passed since their first meeting on that train bound for Vienna. It's a story of the star-crossed lovers that takes place just before the clock strikes midnight. Stars Ethan Hawke and Julie Delpy. Rated R.


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A gorgeous, hand-crafted instrument ideal for pros and hobbyists
Strap on a set of cans and check out GW's guide to 10 essential headphone albums.
The new five-song EP by this talented artist
Five-plus examples of Stevie Ray Vaughan's best work as a guest guitarist in the Eighties.
Pro Tone Pedals has launched its new Mark Holcomb Limited Edition Signature Delay Pedal. The Periphery guitarist's signature pedal, the Haunted Delay, was designed to be an ambient-style delay like your favorite vintage tape echo, with gig-ready durability to last you decades without a $1,000 price tag.
"[This is] a gear demo I did last week for Positive Grid (makers of Bias and JamUp for iOS). I'm jamming through a couple of riffs using a custom amp in Bias and running through several features in JamUp. I also play through some new Periphery material."
Hey, everyone. Mark Holcomb of Periphery here with a list of my five most influential guitarists. Enjoy!
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We're SorryClose
I Heart My Family Contest
My brother, my best friend
- Contest Photo by: brittfamighetti
- Valley Stream, NY
Brief Description:
This has always been my favorite picture of my brother and I because it pretty much sums up our relationship. I love the look on his face. It screams, "how did I get stuck with this crazy girl on my back?!" I, on the other hand, love it. I absolutely adore my brother and we always have so much fun together. Now that I am away for college, I don't get to see him often, but when I look at this picture I can't help but laugh because it always makes me smile. I'm so thankful that he is in my life :)
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- With a digital camera, you can take as many photos as possible and choose the best one. Have fun!


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A composition including lecithin which is useful for defoaming liquids, such as blood. In one aspect of the invention the composition includes inorganic particles. In another aspect of the invention the composition includes a silicone.
1. A cardiotomy reservoir comprising a surface coated with a non-silicone composition comprising lecithin and inorganic particles.
2. The cardiotomy reservoir of claim 1 wherein the composition further comprises a diluting agent.
3. The cardiotomy reservoir of claim 2 wherein the diluting agent is selected from the group of water and alcohol.
4. The cardiotomy reservoir of claim 2 wherein the ratio of diluting agent to lecithin is at least about 7:1.
5. The cardiotomy reservoir of claim 1 wherein the lecithin is soy lecithin.
6. The cardiotomy reservoir of claim 1 wherein the inorganic particles are silica particles.
7. The cardiotomy reservoir of claim 1 wherein the surface on which is coated the composition forms a part of an open cell sponge.
8. The cardiotomy reservoir of claim 1 which is a part of an extracorporeal circuit.
9. A device comprising a non-silicone antifoam composition comprising lecithin and inorganic particles.
10. The device of claim 9 which forms a part of an extracorporeal circuit.
11. The device of claim 9 comprising a surface on which is coated the antifoam composition.
12. The device of claim 9, wherein the device is a fluid handling device.
13. The device of claim 9, wherein the device is a blood handling device.
14. The device of claim 9, wherein the device is a blood reservoir.
From the first operation to repair a heart in 1891 until the early 1950's, heart surgeons were limited by the problem of trying to work on the heart while it was still beating. The heart's constant motion, and the presence of blood that obscured the surgeon's view, made repairing heart defects a surgical challenge. Surgeons had to work quickly and there was always a danger of disrupting blood circulation to vital organs. The solution to this problem came in the late 1950's with the development of the first oxygenator.
The veins return deoxygenated blood to the heart's right atrium. From the right atrium, blood is pumped to the right ventricle, then through the pulmonary artery to the lungs. The lung oxygenates the blood while removing carbon dioxide as it passes through the lung's alveolar capillary network. Oxygenated blood is then returned to the left atrium by way of the pulmonary veins. Blood is then pumped through the mitral valve into the left ventricle and pumped back into the body's circulatory system. Cells are replenished with oxygen and carbon dioxide is taken up by the blood as the blood passes through the body's capillary system. After this gaseous exchange is accomplished, the blood is returned to the heart and the cycle is repeated.
During cardiopulmonary by-pass (CPB) surgery, for example, venous blood is taken from the patient's circulation by means of a cannula placed in the vena cava. The blood �by-passes� the heart and lungs and enters what is referred to as the �extracorporeal circuit� or literally a circuit �outside the body.� Oxygenation of the patient's blood takes place in an oxygenator much in the same way as it does in the natural process. After the blood is oxygenated and temperature regulated, it is returned to the patient's arterial circulation through a cannula so that the patient's body may utilize the oxygenated blood.
Early blood oxygenators were called �bubblers� because they bubbled air up through a column of blood, diffusing oxygen into the blood and carbon dioxide out. The problem was that this bubbling action created foam which not only was damaging to the blood, but also rendered this portion useless to the patient.
A defoaming sponge was employed to break down the bubbles of foam back into usable liquid blood. However, the raw sponge by itself was ineffective without a surface agent to lower the surface tension of the blood foam. Silicone Antifoam �A� by Dow Corning was adopted throughout the industry as the defoaming agent of choice. It is comprised of silicone oil and approximately 4.5% silica particles (approximately 5 micrometer (i.e., micron) in diameter). Another development was the use of blood reservoirs to process blood suctioned (scavenged) from the patient during surgery. Antifoam A was used to coat defoaming sponges used in blood reservoirs here as well.
The silicones used in typical silicone antifoams are hydrophobic. Therefore, these compounds are typically dissolved in organic solvents in order to prepare an antifoam solution, which can be applied to a surface to reduce foaming of liquids contacting the surface. The primary solvents that have been used heretofore are chlorofluorocarbons (CFCs) because they are nonflammable and evaporate quickly. Unfortunately, because of recent concerns that CFCs affect the earth's protective ozone layer, the production and use of CFCs will cease in the near future. Thus, there is a need in the art for alternative defoaming compositions having fewer if any detrimental side effects to the individual and the environment.
The present invention provides compositions comprising (and preferably, consisting essentially of) lecithin, such as soy lecithin, and preferably inorganic particles, such as silica particles, and optionally a diluting agent. Such compositions are particularly suitable as defoaming (i.e., antifoaming) compositions. Typically, such compositions are coated on a surface of an article, such as a surface in a cardiotomy reservoir. Alternatively, however, compositions of the present invention can be added directly to a liquid prone to foaming.
Preferably, compositions of the present invention also include a diluting agent, such as water or alcohol. Optionally, compositions of the present invention can include a silicone. In preferred compositions, the ratio of diluting agent to lecithin is at least about 7:1 parts diluting agent to lecithin, and the amount of inorganic particles is preferably about 2 weight-% to about 20 weight-% inorganic particles, based on the weight of the lecithin in the composition.
Surfaces on which compositions of the present invention can be coated for desired effect include surfaces of devices through which liquids prone to foaming pass or are stored, for example. This includes portions of extracorporeal circuits, particularly cardiotomy reservoirs. Alternatively, instead of being directly coated on a surface of a device through which a liquid passes or is stored, compositions of the present invention can be coated on articles that are placed in such devices, such as defoaming sponges, which are often open cell sponges, for example.
The present invention also provides a method of reducing foaming in a liquid prone to foaming. The method includes contacting the liquid prone to foaming with an antifoam composition comprising lecithin and inorganic particles, wherein the amount of foam present in the liquid combined with the antifoam composition is decreased relative to the same liquid under the same conditions without the antifoam composition. Such liquids prone to foaming include, for example, blood, milk, beer, and soda.
The composition can be added to the liquid prone to foaming or be coated on a surface with which the liquid comes in contact. Such methods are typically performed during surgery, such as cardiopulmonary surgery, orthopedic surgery, and thoracic surgery, and are used to reduce foaming in blood. Preferably, at least one characteristic of foaming in a liquid, such as blood, is reduced. That at least one characteristic is selected from the group of wicking, streaming, spotting, scud formation, and backup/overflow.
Significantly, by reducing foaming in blood, trauma to the blood can be reduced. Thus, the present invention provides a method of reducing trauma to blood in an extracorporeal circuit comprising combining blood with a composition comprising lecithin and inorganic particles. This combining step typically occurs by coating one or more surfaces of the extracorporeal circuit or an article therein, such as a sponge, with which the blood comes in contact with the antifoam composition.
A �cardiotomy reservoir� can be part of a device used to store blood that has been removed from a patient until the blood is returned to the patient. The �cardiotomy reservoir� includes a surface, e.g., a defoaming sponge, that is used to decrease the amount of foam in the blood removed from the patient, and the reservoir into which blood flows immediately following treatment to decrease foaming. The device that of which the �cardiotomy reservoir� forms a part is referred to as an �extracorporeal circuit.� Extracorporeal circuits include, for example, oxygenators, reservoirs, filters, tubing, connectors, valves, sensors, and devices used to scavenge blood from a patient during surgery.
�Foam� refers to a gas dispersed in a liquid such that bubbles are formed. �Defoam,� �defoamed,� and �defoaming� refer to decreasing the amount of foam in a liquid by decreasing the amount of gas dispersed in the liquid. The amount of foam present in a liquid can be determined by, for instance, measuring the volume of foam present on top of the liquid containing the foam.
�Defoaming sponge� refers to a surface that can be used to decrease foaming of a liquid. Typically, a liquid prone to foaming flows through the defoaming sponge and causes a decrease in the amount of foam in the liquid. A �defoaming sponge� is typically an open cell sponge.
A �liquid prone to foaming� refers to a liquid that, when subjected to certain conditions including, for instance, oxygenation or mixing, forms a foam.
FIG. 1. A cardiotomy reservoir.
FIG. 2. An extracorporeal circuit.
The present invention is directed to a composition including lecithin. In one aspect of the invention the composition includes inorganic particles. In another aspect of the invention the composition includes a silicone. The silicone can be present in a silicone antifoam, which is a mixture of silicone oil and silica particles. The composition can further include a diluting agent. The compositions (optionally referred to herein as antifoam agents or antifoam compositions) can be used to coat surfaces that contact liquids prone to foaming or added directly to liquids prone to foaming. Preferably, the surface is in an extracorporeal circuit, more preferably in a cardiotomy reservoir, most preferably a defoaming sponge in a cardiotomy reservoir. Preferably, the liquid prone to foaming is blood. Preferably, the blood is present in an extracorporeal circuit during, for example, cardiovascular surgery, or orthopedic surgery, or thoracic surgery. Alternatively, the blood is suctioned from a patient during surgery. Typically, blood removed from a patient during surgery is oxygenated and/or stored in a reservoir.
Some aspects of the invention are beneficial as they have fewer detrimental effects to the environment. In particular, certain preferred compositions of the present invention are water based and do not require the use of environmentally harmful CFC solvents. Moreover, some of the compositions of the present invention reduce the detrimental side effects that may occur from using silicones as defoaming agents. Thus, certain preferred embodiments do not include a silicone.
It was originally hypothesized that the levels of lecithin needed to decrease foaming would be identical to the levels of silicone antifoam. Surprisingly, it was unexpectedly found that less lecithin was needed to function substantially the same as the silicone. This is an advantage, as a liquid prone to foaming is exposed to a lesser amount of a composition of the present invention to effectively decrease foaming. Moreover, it was not expected that silica particles would play such a major role in the compositions that do not include silicone. It was originally hypothesized that all that need be done to defoam blood is to reduce its surface tension by introduction of lecithin. However, the bubbles that form foamed blood are very tenacious, being surrounded with a layer of protein. Apparently, the silica particles provide, through abrasive interaction with the blood bubble, the introduction of the surface tension reducing agent needed to pop the bubble. Typically, without the inorganic particles, the agent cannot effectively penetrate the bubble surface.
Lecithin is a naturally occurring substance that can be obtained from, for example, soybean or egg. Lecithins are typically mixtures of diglycerides of fatty acids linked to the choline ester of phosphoric acid, and are classed as phosphoglycerides or phosphatides (phospholipids). Lecithin can contain differing amounts of other compounds depending on the method of isolation. Typically, commercial lecithin is a mixture of acetone-insoluble phosphatides. Preferably, the lecithin is obtained from seeds including soybean and corn, most preferably soybean, using methods well known in the art. Lecithin obtained from soybean is referred to herein as soy lecithin. Although lecithin can also be derived from egg yolk, the pharmaceutical industry has focused on soy based lecithin because of its lower risk of disease. For instance, soy lecithin has been used extensively in the intravenous (I.V.) feeding industry.
Lecithin, in its various mixtures, is sold under such commercial trade names as Central Soya CENTROMIX E lecithin, Product Code #6230, available from Central Soya (Fort Wayne, Ind.), and PHOSPHOLIPON 90H lecithin, (American Lecithin Co., Oxford, Conn.). Preferably, Centromix E or PHOSPHOLIPON 90H lecithin is used in compositions of the present invention. Preferably, in applications requiring high purity (e.g., intravenous applications or blood defoaming), PHOSPHOLIPON 90H lecithin is used. Alternatively, CENTROMIX E lecithin can be used in applications not requiring high purity. The composition can be prepared by mixing lecithin and inorganic particles together, optionally with a diluting agent. Various combinations of lecithins, inorganic particles, and diluting agents can be used if desired. Preferably, for such embodiments, the compositions include at least about 7 weight-% lecithin, more preferably at least about 10 weight-% lecithin, and most preferably at least about 12 weight-% lecithin, based on the total weight of the lecithin and diluting agent. Preferably, for such embodiments containing lecithin and silica (without silicone) the composition contains no more than about 20 weight-% of lecithin, based on the total weight of the lecithin and diluting agent.
The particles useful in the present invention include inorganic particles. The particles are typically in the form of an amorphous sol or an amorphous powder. The use of a powder can result in an intractable mass. However, with the proper mixing equipment (for instance a shear mixer) and care in adding ingredients (e.g., adding ingredients slowly, using heat as described herein to encourage solubility, or first mixing particles into the diluting agent then adding the lecithin), problems with having a mass are avoided. Powders and sols useful in the present compositions can be prepared by methods well known in the art. As used herein, �sol� refers to a colloidal dispersion of substantially non-aggregated, inorganic particles in a liquid medium. Colloidal silicas dispersed as sols in aqueous solutions are available commercially under such trade names as LUDOX (E.I. DuPont de Nemours and Co., Wilmington, Del.), NYACOL (Nyacol Co., Ashland, Mass.), and NALXO (Nalco Chemical Co., Oak Brook, Ill.). Nonaqueous silica sols (also called silica organosols) are also commercially available under the trade names NALCO 1057 (a silica sol in 2-propoxyethanol, Nalco Chemical Co.), and MA-ST, IP-ST, and EG-ST (Nissan Chemical Ind., Tokyo, Japan). Amorphous silicas are commercially available under such trade names as SYLOID 244 (WR Grace Davison Chemical Division, Baltimore, Md.). Preferably, the inorganic particle is silica, most preferably, SYLOID 244.
In addition to silica, other inorganic particles may be used, including, but not limited to, alumina, titania, zirconia, ceria, and antimony oxide, all of which are available commercially as sols from suppliers such as Nyacol Co., Ashland, Mass., and Nalco Chemical Co., Oak Brook, Ill. Various combinations of inorganic particles can be used if desired.
The inorganic particles preferably have an average particle diameter of at least about 4 microns to about 6 microns, and more preferably, about 5 microns. In applications where the composition contacts a liquid prone to foaming that is to be introduced into a patient (e.g., blood, intravenous solution) the inorganic particles preferably have an average particle diameter of no greater than about 7 microns. In other applications it is expected that there is no upper limit on the inorganic particle. The approximate particle size distribution may typically be a minimum of 99.95% on a US Standard screen through 325 mesh. Average particle size can be measured using transmission electron microscopy to count the number of particles of a given diameter. Preferably, compositions of the present invention include at least about 2 weight-% inorganic particles, more preferably at least about 3 weight-% inorganic particles, and most preferably at least about 5 weight-% inorganic particles, based on the weight of the lecithin used in the composition. Preferably, the composition contains no more than about 20 weight-% inorganic particles, based on the total weight of the lecithin.
If desired, compositions of the present invention include a diluting agent. Useful diluting agents include water, alcohols, and chlorinated hydrocarbons (CFCs). The type of diluting agent useful in a composition depends on the composition to be defoamed. When the liquid prone to foaming is used in the food industry, preferably the diluting agent is water. When the liquid prone to foaming is present in an extracorporeal circuit, preferably the diluting agent is an alcohol, more preferably isopropanol or ethanol. Alcohols have the added benefit of readily evaporating. Preferably, the diluting agent is water, an alcohol, or mixtures thereof. The ratio of diluting agent to lecithin can vary depending on the application. For example, for blood, a ratio of 12:1 (parts diluting agent to lecithin) is particularly desirable. For other liquids, other concentrations may be desired, which can be determined by one of skill in the art.
As stated above, a silicone can be included in the compositions of the present invention. Typically, a silicone is added as a part of a silicone antifoam. Silicone antifoams useful in the present invention include Silicone Antifoam-A (Dow Corning, Midland, Mich.) and silicone antifoams made by GE Silicones (Waterford, N.Y.) and Union Carbide Corp., (Danbury, Conn.). Preferably, Silicone Antifoam-A is used. The composition can be prepared by mixing lecithin, silicone antifoam, and a diluting agent. Useful diluting agents include water, alcohols, and chlorinated hydrocarbons (CFCs). The type of diluting agent useful in a composition depends on the composition to be defoamed. When the liquid prone to foaming is used in the food industry, preferably the diluting agent is water. When the liquid prone to foaming is present in an extracorporeal circuit, preferably the diluting agent is an alcohol, more preferably isopropanol or ethanol. Preferably, such embodiments include at least about 20 weight-% lecithin, more preferably at least about 25 weight-% lecithin, most preferably at least about 30 weight-% lecithin, where the weight-% lecithin is calculated based on the weight of silicone antifoam present in the composition, not on the weight of the total composition. Preferably, such compositions that include a silicone antifoam contain no more than about 50 weight-% lecithin. Preferably, the ratio of diluting agent to silicone antifoam is at least about 10 parts to 1 part, and more preferably at least about 16 parts to 1 part. Preferably, the composition contains no more than about 20 parts to 1 part diluting agent to silicone antifoam.
Methods can be used to produce a homogenous mixture of lecithin and the other components of the present invention, preferably, silica particles, and optionally a diluting agent. A homogenous mixture can be obtained by using a homogenizer or a shear mixer. Typically, if a diluting agent is used, the composition is preferably prepared by mixing a diluting agent with soy lecithin and then adding inorganic particles. Without intending to be limiting, mixing can be done at, for instance, 2,500 RPM. Optionally, the temperature of the composition components can be increased before mixing and/or during mixing to aid the mixing process. Preferably, the components of the composition are heated separately before being combined and mixed. Preferably, the components are heated, either individually or in a mixture, to about 60� C., more preferably to about 75� C., most preferably to about 90� C.
Compositions of the present invention can be used in methods to reduce foaming in a liquid prone to foaming. For example, the composition can be added directly to the liquid, or the composition can be used to coat a surface that the liquid will contact. For instance, the composition can be added directly to liquids during food preparation, such as beer, milk, or soda, or directly to medicines, such as intravenous feeding products, or to liquids used in sewage and wastewater treatment plants.
Alternatively and preferably, a composition of the present invention is used to coat a surface that the liquid will contact. For instance, the compositions can be applied to a surface that is part of an apparatus, e.g., an extracorporeal circuit, that comes in contact with a liquid prone to foaming. Such surfaces also include an open cell sponge present in a cardiotomy reservoir, semi-permeable membranes including, for instance, an asymmetric microporous hollow fiber membrane, and simple substrates including, for example, the tubes of an extracorporeal circuit. Preferably, the surface is a part of a sponge, such as an open cell sponge. For an article such as an open cell sponge, a composition of the present invention can be coated on an external surface or impregnated into the body such that internal surfaces are coated.
An open cell sponge useful in the invention is typically made up of a plastic polymer containing pockets of air or gas introduced before the plastic has cured. Open cell sponges are produced using methods known to the art. The open cell sponge can be made of polyurethane, polyester, or polyethylene, and preferably, polyurethane.
Surfaces can be coated with the compositions by spraying or by atomizing. Spraying the composition onto a surface can be accomplished by loading the composition into a pressure pot having a pressure set at about 20 psig to about 60 psig (depending on the size of the sponge to be treated) and forced through a nozzle (preferably with 0.028 inch fluid orifice and 0.050 inch air orifice) (part number 2850SS, available from Spray Manufacturing Systems Co., Laguna Hills, Calif.). Typically, the composition is not diluted when it is to be sprayed, except in high purity applications where the lecithin is dispersed in water or alcohol prior to usage.
Alternatively, the surface can be coated by dipping the surface into the composition, or when being applied to the tubing of an extracorporeal circuit, the circuit can be flushed with the composition. When the composition is to be applied to a surface in a manner other than spraying, the composition is typically diluted with a diluting agent. Typically the surface is allowed to dry before use. The surface can be allowed to dry at room temperature. Alternatively, the surface can be allowed to dry in an oven for about 4 hours to about 12 hours. Preferably, the temperature of the oven is about 50� C. to about 70� C. In general, conditions for drying can vary depending on, for example, the substrate and/or the mixture concentration.
If necessary, the coated surface can be sterilized. Sterilization methods include gamma irradiation by Cobalt 60, irradiation by e-beam, and by ethylene oxide.
Typically, the performance of a coated surface can be evaluated in a Defoaming Performance Test. This test compares the behavior of coated and uncoated surfaces, or surfaces coated with different compositions. Preferably, the surface is a defoaming sponge. A liquid prone to foaming, preferably blood, entering an extracorporeal circuit is mixed with an equal volume flow rate of air to create a foamed liquid. The air is either introduced with positive pressure or a vacuum is connected to the extracorporeal circuit to draw the air into the liquid and control the blood flow. Preferably, a vacuum is connected to the extracorporeal circuit to draw the air into the liquid. The ability of the coated surface is measured by how well it reduces the foam to useable liquid.
Referring to FIG. 1, performance of an antifoam composition on a defoaming sponge 1 can be assessed by visual observation of several parameters, which are described by referencing the cardiotomy reservoir 2 that includes a defoamed liquid 3 present in a receptacle 4. Compositions of the present invention provide improvement in at least one, and preferably, more than one, of the following parameters: i) spotting, i.e., the localized absorption of liquid on the filter assembly 5 (typically, containing filtration media such as felt) above the defoamed liquid level 6; ii) wicking, i.e, the absorption of liquid on the filter assembly 5 above the defoamed liquid level 6; iii) streaming, i.e., stream of liquid breaking through the filter 5 above the defoamed liquid level 6; iv) scud formation, i.e., the formation of microbubbles on the defoamed liquid level 6 of the defoamed liquid 3 present in the portion 4 of the cardiotomy reservoir 2, i.e., downstream of the defoaming sponge 1 and filter assembly 5; and v) backup/overflow, e.g., the flow of liquid and/or foam directly over or around the filter assembly 5 and into the reservoir 4 of the cardiotomy reservoir 2. Backup/overflow is an indication of device failure. Another indication of failure is macroemboli flowing over the top of the filter assembly 5 and into the blood reservoir.
Typically, the performance of a coated surface can also be evaluated in a Blood Trauma Test. Since foaming damages blood, a blood trauma test can be used to assess the benefit provided by antifoam compositions of the present invention. Typically, blood trauma is measured in at least one of three ways: (1) assessing breakage of red blood cells by measuring generated plasma hemoglobin; (2) platelet depletion over the time of the assay relative to the number of platelets present at the beginning of the assay; and (3) white blood cell depletion over the time of the assay relative to the number of white blood cells present at the beginning of the assay. Compositions of the present invention provide improvement in at least one of these parameters, and preferably, in more than one of these parameters.
The present invention is illustrated by the following examples. It is to be understood that the particular examples, materials, amounts, and procedures are to be interpreted broadly in accordance with the scope and spirit of the invention as set forth herein.
Coating of INTERSEPT 1351 Cardiotomy Reservoirs with a Composition Comprising Soy Lecithin, Water, and Silica Particles, the Lydall Aqueous Process, or with Silicone Antifoam A.
The composition was prepared by mixing ten parts water with one part soy lecithin (Centromix E) by weight. The two components were heated to 60� C., then mixed together by shear mixing for 10 minutes at as high a speed as possible without sucking air into the emulsion. Approximately 4% to 5% of 5 micron silica particles (Syloid 244 FP) were added. Two INTERSEPT defoaming sponges from INTERSEPT 1351 cardiotomy reservoirs (Medtronic, Inc., Anaheim, Calif.) were dipped into the lecithin solution and allowed to dry, and then assembled into the cardiotomy reservoir. These reservoirs were labeled T3 and T4.
Two INTERSEPT defoaming sponges were prepared using the Lydall Aqueous Process by a proprietary process (Lydall Westex, Inc., Hamptonville, N.C.). These reservoirs were labeled T1 and T2.
Six cardiotomy reservoirs were used as production controls. A production control contains an INTERSEPT defoaming sponge coated with Silicone Antifoam A. The Silicone Antifoam A was applied using Freon (10 parts Freon to 1 part antifoam) to disperse it, followed by dipping of the sponges and volatilization of the Freon. These reservoirs were labeled C1-C6.
Evaluation of Blood Defoaming Characteristics.
A Defoaming Performance Test was conducted in vitro comparing cardiotomy reservoirs containing surfaces treated with the soy lecithin-silica particle composition with cardiotomy reservoirs containing surfaces treated with either the Lydall process composition or Silicone Antifoam A. The test was run using an extracoporeal circuit schematically depicted in FIG. 2 that included a cardiotomy reservoir schematically depicted in FIG. 1. The circuit 10 shown in FIG. 2 includes a cardiotomy reservoir 12 (of the type shown in FIG. 1), a gas flow meter 14, a sample port 16, a roller pump 18, and a reservoir 20. The test was run for 6 hours. This blood flow was combined with introduction of air bubbles in the ratio of 1:1 (blood flow to air flow). Foam was thus generated and a relative comparison was made.
After assembly of the cardiotomy reservoirs, fresh anticoagulated bovine blood was filtered and diluted to a hemoglobin of 9.0�0.3 g/dl. Two liters of blood were added to the device reservoir 1 and the test was begun. Defoaming testing was performed at Qb:Qg=2:1 LPM. This refers to the ratio of blood flow rate into the device in liters per minute (LPM) to the rate of gas introduced in liters per minute. Thus there were 2 liters per minute of blood entering the device for every 1 liter of gas introduced to create foam. Defoaming characteristics were evaluated at 30 minute intervals, for six hours, while maintaining the cardiotomy reservoir fluid level at 200 ml. Performance of treated and control reservoirs in the Defoaming Performance Test was assessed by visual observation of wicking, streaming, spotting, scud formation, and backup/overflow.
All four test samples (T1, T2, T3, and T4) exhibited scud within the first thirty minutes (T2 and T3 at 15 minutes; T1 and T4 at 30 minutes). Four of the six controls exhibited scud at thirty minutes, one at sixty minutes and one did not during the 6 hour recirculation period. Both Centromix E samples (T3 and T4) failed during the six hour period (one at 120 minutes and one at 210 minutes), while two of the controls failed (one at 210 minutes and one at 240 minutes) and neither of the Lydall samples failed. One each of the test samples exhibited spotting (T3 at 30 minutes; T1 at 330 minutes), while none of the controls did. One of the Centromix E samples exhibited streaming (T3 at 30 minutes) while none of the Lydall samples or the controls did.
Summary�The Lydall product was inconsistent where T1 performed well compared to controls, while T2 did not. T3 and T4 were more consistent, but did not exhibit a high enough defoaming action to be comparable to controls.
Coating of INTERSEPT 1351 Cardiotomy Reservoirs with a Composition Comprising Soy Lecithin, Water, and Standard Silicone Antifoam A.
The following three compositions (Table 1) were produced by heating each ingredient to 65� C. before combining. The 300 ml volume of water was combined with the Centromix E/Silicone Antifoam A mixture and mixed by shear mixing for 10 minutes at as high a speed as possible without sucking air into the emulsion. The remaining volume of water was then added and mixed. Seven INTERSEPT defoaming sponges were dipped into each composition and dried. After assembly, the cardiotomy reservoirs were sterilized by gamma irradiation. The results for the production controls tested in Example 1 were used in evaluating the reservoirs in this Example.
Evaluation of Blood Trauma and Defoaming Characteristics.
The INTERSEPT cardiotomy reservoirs were evaluated in vitro to determine the effect of various amounts of Centromix E emulsifier on blood trauma characteristics and defoamer performance. All test samples were comparatively evaluated against production controls. Three reservoirs from each of group 1, group 2, and group 3 and three production controls were tested for blood trauma. Four reservoirs from each of group 1, group 2, and group 3 and four production controls were evaluated for defoaming.
The cardiotomy reservoirs were tested for blood trauma at Qb=Qg=1 LPM, room temperature, 11.5�0.3 g/dl hemoglobin. Defoaming testing was performed at Qb=Qg=1 LPM on two each of the test samples and two of the controls, and at Qb=2 LPM; Qg=1 LPM on two each of the test samples and two of the controls.
Blood Trauma
Mean values for cardiotomy reservoirs of groups 1 and 3 were either not significantly different or significantly lower (p<0.05) than those of the controls, while mean six hour generated plasma hemoglobin for cardiotomy reservoirs of group 2 was significantly higher (35.3�6.3 mg/dl vs. 23.4�2.4 mg/dl, p<0.05) than that of the controls.
All test samples did not exhibit wicking, streaming, spotting or scud at Qg=Qb=1 LPM, while all six of the production controls exhibited wicking by 210 minutes into the test. By the end of the six hour recirculation period, the test cardiotomy reservoirs had lower prefilter backup (group 1=500 ml, group 2=600 ml, group 3=500 ml, mean values) than the controls (1200 ml, mean value).
At the Qb=2 LPM; Qg=1 LPB portion of the defoaming, four of the six controls exhibited scud earlier than the test samples. Controls exhibited scud at 30 minutes while one test unit in group 2 held out until 90 minutes, and one unit in each of groups 1 and 3 held out until 150 minutes. Two of the controls failed during the six hour recirculation period (one at 210 minutes and one at 240 minutes), while none of the test samples failed. Three of the test units exhibited spotting (one from group 3 at 150 minutes, one from group 1 at 180 and a second one from group 1 at 270 minutes) while none of the controls did. One of the test samples exhibited streaming before the controls (one from group 1 at 180 minutes compared to three controls at 210 minutes). By the end of the six hour recirculation period, the test samples had significantly lower prefilter backup than the controls.
Summary�For blood trauma: A) General Plasma Hemoglobin for Group 1 was comparable to controls; Group 2 comparable thru 4 hours, then slightly higher at 6 hours; Group 3 comparable. B) Platelet depletion for Group 1 was significantly better than controls; Group 2 even more significantly better than controls; Group 3 same as group 2. C) White blood cell depletion: All groups comparable to controls. For defoaming all test units were significantly better than controls.
The complete disclosures of all patents, patent applications, and publications that are cited herein are hereby incorporated by reference as if individually incorporated. Various modifications and alterations of this invention will become apparent to those skilled in the art without departing from the scope and spirit of this invention, and it should be understood that this invention is not to be unduly limited to the illustrative embodiments set forth herein.
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Numbers are in for the state budget, and reports estimate that the state's general-fund surplus will be nearly six-million dollars more than projected at the end of the two year budget cycle.
Officials telling lawmakers during the week that the state is on track to have close to $350,000,000 at the end of the 2015 budget period.
Chairman of the Legislative Finance Committee Llew Jones of Conrad says that while things can change in two years with the forecast, the budget is right around where it was projected to be and that he does appreciate that it is staying close to it to keep the budget balanced.
Jones also said that the only fund that is expected to be less is the public employees retirement system which is close to seven million dollars less. He said though that is due to less than expected revenue from coal taxes and trusts.


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The Transformation of Rural LifeThe University of North Carolina Press 1994; US$ 29.99
Transformation of Rural Life: Southern Illinois, 1890-1990 more...
It Happened in Southern IllinoisSouthern Illinois University Press 2010; US$ 24.95
In this collection of articles describing the people, places, and folkways of southern Illinois, John W. Allen provides entertaining and informative glimpses into the region's past. Included here are sketches of the early pioneering days when wolves were literally chased from the door, stories about the many Indian artifacts discovered among... more...
Legends and Lore of Southern IllinoisSouthern Illinois University Press 2010; US$ 24.95
In the 1950s and '60s, John W. Allen told the people of southern Illinois about themselves—about their region, its history, and its folkways—in his series of newspaper articles, "It Happened in Southern Illinois." Each installment of the series depicted a single item of interest—a town, a building, an enterprise,... more...
City WatchUniversity of Iowa Press 2001; US$ 20.00
In forty-five years as one of Chicago's liveliest journalists for Time, Life, and the Chicago Tribune, Jon Anderson has established a reputation for picking up on what someone once called "the beauty of the specific fact." Part "Talk of the Town," part On the Road with Charles Kuralt, Anderson's twice-a-week "City Watch" columns in the Chicago Tribune... more...
Maria's JourneyIndiana Historical Society Press 2013; US$ 14.95
Born into the Mexican Revolution, Maria Perez entered an arranged marriage at age fourteen to Miguel Arredondo. The couple and their tiny daughter immigrated to the United States in the 1920s, living in a boxcar while Miguel worked for a Texas railroad and eventually settling in East Chicago, Indiana, where Miguel worked for Inland Steel. Their story... more...
Life LinesOxford University Press 1996; US$ 59.99
This text is intended for sociologists and anthropologists interested in ethnicity, community and integration amongst Asian Indian immigrants. more...
Mexican Hometown Associations in Chicagoac�nRutgers University Press 2014; US$ 26.95
�In this groundbreaking new book, Mexican Hometown Associations in Chicagoac�n , X�chitl Bada reveals how Mexican hometown associations, groups consisting of immigrants from the same small towns, have become a surprisingly powerful force for mobilizing social change in both the United States and�Mexico. By giving voice to the members of a group of... more...
Chicago's New NegroesThe University of North Carolina Press 2007; US$ 29.99
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The Underground Railroad in DeKalb County, IllinoisMcFarland & Company, Inc., Publishers 2013; US$ 45.00
This book is about previously unidentified people who became Abolitionists involved in the antislavery movement from about 1840 to 1860. Although arrests were made in nearby counties, not one person was prosecuted for aiding a fugitive slave in DeKalb County, Illinois. First, the area Congregationalist, Universalist, Presbyterian and Wesleyan Methodist... more...
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What really happened in Mrs. O'Leary's barn that autumn night in Chicago? Though no one knows for sure, what is certain is someone, or something, ignited a load of hay on fire, and the city of Chicago would never be the same. The Great Chicago Fire of 1871 raged for more than 24 hours, obliterating the downtown and sparking a mass exodus to... more...


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Red Bull Curates: Canvas Cooler Project winners on display at SCOPE Miami
Artists competed in three cities to have their work displayed during Art Basel Weekend
Ten of the nation's top emerging contemporary artists are headed to SCOPE Miami during Art Basel (Dec. 4 – 9, 2012) to showcase their work in a group show after being chosen as winners in a nationwide series of competitive gallery showcases.
Red Bull Curates: Canvas Cooler Project paired emerging artists in Los Angeles, Chicago and New York with local venue owners to create custom and functional pieces of art which are now on permanent display in some of the hottest bars, lounges and restaurants in each city.
Artists were handpicked and given a one-day challenge to transform a blank canvas-wrapped Red Bull cooler into an inspired work of art.
The show will take place at SCOPE Pavilion (110 N.E. 36 St.) in Midtown and will be open from Dec. 4 - 8 from 11 a.m. – 7 p.m. and Dec. 9 from 11 a.m. – 6 p.m.
To RSVP visit www.redbullusa.com/curates
Art Basel
Art Basel
- Art work donated to FIU by Jorge Pérez may be forgery
- Accessible Art: Art Basel sets attendance record, color in time and space with Carlos Cruz-Diez, and the Bakehouse Art Complex builds first public metal-casting foundry
- Cindy Crawford pays visit to Art Miami for debut of work in her likeness
- FAILE Brings Their Interactive Deluxx Fluxx Arcade Installation to South Beach
- De Nolet festival brings together performance art, music and Ketel One cocktails
- Wynwood-based Spinello Projects unveils exhibit in Art Basel's competitive Nova sector
- Miami muralist Krave leads team of artists to spotlight Wynwood Central during Art Basel
- KIND hosts community mural project
- Art Basel opens this week in an increasingly cultured city
- Accessible Art: Arsht Center exhibit fuses fashion and art, a call for artists at Segafredo, and the Wolfsonian-FIU presents Rebirth of Rome


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Linux Plumbers Conference EndsSep 20, 2008
The third and final day of the Linux Plumbers Conference, a conference designed by developers for developers, featured two final microconferences: one focused on Dbus Desktop Integration, and the other on Future Displays and Input Devices.more »
Kroah-Hartman Attacks CanonicalSep 19, 2008
Greg Kroah-Hartman's keynote address at the Linux Plumbers Convention 2008 was officially about the Linux Ecosystem, but started as a direct attack on Ubuntu developer Canonical. He claims that the company contributes next to nothing to kernel development.more »
Linux Plumbers Conference ContinuesSep 18, 2008
The second day of the Linux Plumbers Conference got off to a productive start with an address by Jonathan Corbet, co-founder of LWN.net. "The Kernel Report" covered the challenges facing the kernel development community and the current or pending responses to those challenges, as well as a short summary of the Kernel Summit held earlier this week.more »
KVM Kernel-based virtualization with KVMSep 05, 2008
KVM brings the kernel into the virualization game. We'll explain why the Linux world is so interested in this promising virtualization alternative.more »
Kernel NewsSep 01, 2008
New Stable Kernel 18.104.22.168Aug 04, 2008
Kernel developer Greg Kroah-Hartman recently announce the latest stable kernel version. The Minor Update 22.214.171.124 contains bugfixes, updates, and new drivers.more »
Kernel NewsAug 01, 2008
Torvalds Announces First Kernel 2.6.27 Release CandidateJul 31, 2008
Linus Torvalds has announced the first Release Candidate of the next kernel version 2.6.27 on the Linux Kernel Mailing List (LKML); this signals the end of the merge window.more »
Issue 166/2014
Buy this issue as a PDF
Tag Cloud
Knoppix 7.4 Released
Klaus Knopper announces the latest version of his iconic Live Linux system.
PHP Attack Puts WordPress and Drupal at Risk
All websites that use these popular CMS tools could be vulnerable to denial of service attacks if users don't install the updates.
Heartbleed Bleeds On
According to a report, many potential victims of the Heartbleed attack have patched their systems, but few have cleaned up the crime scene to protect themselves from the effects of a previous intrusion.
Drone Brain Goes Open Source
DARPA and NICTA release the code for the ultra-secure microkernel system used in aerial drones.
Password Management Services Vulnerable to Attack
Should you trust an online service to store your online passwords?
New Raspberry Pi Adds Two USB Ports
New B+ board lets you build cool things without the complication of a powered USB hub.
Microsoft Grabs No-IP.com Domains
Redmond rushes in to root out alleged malware haven.
Firefox Steps into 3D
New initiative will bring futuristic virtual reality effects to the web surfing experience.
New Trojan Targets Online Banking
Dyreza malware launches a man-in-the-middle attack that compromises SSL.
HP Rolls Out Massive Cloud Network
New cloud combines worldwide access with local attention to data security.


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Book your room at Hotel Santorini
Double or Twin RoomMax Occupancy: 3 guests (up to 1 child, 2 infants)
Triple RoomMax Occupancy: 3 guests (up to 2 children, 2 infants)
Single RoomMax Occupancy: 2 guests (up to 1 infant)
Hotel with a restaurant, in Krakow (Nowa Huta)
This hotel is located in Krakow (Nowa Huta), close to Laznia Nowa Theatre, M1 Shopping Center, and Polish Aviation Museum. Local attractions also include EC Krakow Headquarters and Krakow Aquapark.
Hotel Features
In addition to a restaurant, Hotel Santorini features a sauna. Other amenities include complimentary wireless Internet access and dry cleaning/laundry services.
Room Amenities
LCD televisions come with satellite channels. Guestrooms also feature complimentary wireless Internet access, complimentary high-speed (wired) Internet access, and desks.Information missing or incorrect? Tell us!
Hotel Santorini
At your hotel
The hotel offers a restaurant. A complimentary breakfast is offered. Public areas are equipped with complimentary high-speed wireless Internet access. 3 meeting rooms are available. This Krakow hotel also offers a sauna, tour/ticket assistance, and multilingual staff. Guests can use the indoor pool at a partner hotel.
- 24-hour front desk
- Babysitting or childcare (surcharge)
- Supervised childcare/activities (free)
- Total number of rooms - 25
- Number of floors - 2
- Complimentary newspapers in lobby
- Free breakfast
- Dry cleaning/laundry service
- Elevator/lift
- Tours/ticket assistance
- Laundry facilities
- Meeting rooms
- Multilingual staff
- Restaurant
- Safe-deposit box at front desk
- Number of meeting rooms - 3
- Sauna
- Number of buildings/towers - 1
- Television in lobby
- Wedding services
- Free Wi-Fi
Stay connected
Available in all rooms: Free Wi-Fi , Free wired high-speed Internet
Available in some public areas: Free Wi-Fi
In your room
- Blackout drapes/curtains
- Phone
- Complimentary bottled water
- Private bathroom
- Complimentary toiletries
- Hair dryer
- Shower only
- Satellite TV service
- Iron/ironing board (on request)
- Complimentary weekday newspaper
- Daily housekeeping
- Turndown service
- Cribs/infant beds (complimentary)
- In-room childcare (surcharge)
- Desk
- Rollaway/extra beds available
- Free Wi-Fi
- Free wired high-speed Internet
Eat and drink
Guests are offered a complimentary buffet breakfast.
Restauracja Santorini - This restaurant specializes in Mediterranean cuisine and serves breakfast, lunch, and dinner. Guests can enjoy drinks at the bar.
The fine print for Hotel Santorini
When you arrive
Check-in time starts at 2 PM
When you leave
Check-out time is noon
How you can pay
Accepted at this hotel: American Express, Diners Club, MasterCard, Visa
Your pets
Pets allowed, Only dogs and cats are allowed
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- A tax is imposed by the city: PLN 1.60 per person, per night
- Resort fee: PLN 1.60 per person, per night
- Pet fee: PLN 15 per pet, per day
- Rollaway bed fee: PLN 50 per night


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Driven By You.
Located in Peoria, Arizona right off the 101 freeway and Bell Road! We are still family owned and family operated after 30 years! Offering a great selection of both new and preowned vehicles. Visit LarryMillerToyota.com for more details!
This dealer has 519 new vehicles.
This dealer has 140 used vehicles.
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261 out of 277 people recommended this dealer.
By writing a dealer review you can provide valuable insights to other customers.
by Terri
I have been a customer at Larry Miller Toyota Peoria for 9 years! I have purchased 3 cars and have always had them serviced there as well. I highly recommend Rick Emerson in the Service Dept, he is great to work with!
on the 2014 Scion FR-SGo to Special Offers


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Queerie Bradshaw
Lauren Marie Fleming is Queerie Bradshaw, but don't tell her mother. A professional over-sharer, Lauren has degrees in film and the law which she mostly uses to analyze porn. A writer, speaker and consultant, Lauren spends her free time working on her blog, watching Disney movies with her nieces and trying to finish her damn memoir already.
Articles by Queerie Bradshaw
Lascivious: How to Hurt the Ones You Love
I'm here to tell you that, even as a radical feminist, it's OK to hit your girlfriend. It is acceptable to strangle her until she taps out. It's perfectly fine to smack her until she's red, bruised, possibly even bleeding. You can do all of this because she asked you to—because i…Mar 13 2013 Queerie Bradshaw Stuff
Lascivious: For the Love of Porn
February is the month of love and there's nothing I love more than porn. Someone on my feed recently posted a quote from a marriage-counseling conference that said, "No one in the history of the world has ever had a better marriage because of pornography." Fuck that.Feb 26 2013 Queerie Bradshaw NSFW
Lascivious: My Bloody Valentine
Except for getting my blood drawn, seeing blood never bothered me. If anything, it intrigued and aroused me. But my relationship with blood changed drastically recently, and now my view of everything from sex to Valentine's Day hearts is skewed.Feb 12 2013 Queerie Bradshaw Stuff
Lascivious: Let Me Entertain You
How a farmer's daughter raised by Republicans ended up a sexpert with a law degree, the girl who speaks at Ivy League schools about the legalities of sweaty stuff, and the newest sex columnist for VICE.Jan 29 2013 Queerie Bradshaw Stuff
Dos & Don'ts
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Things You Learn Designing Porn Banners for a Living
I Went to a Raëlian Cult Protest for Titties
Stress Makes Me Horny
Superstitious People Are Dismembering Albinos in Tanzania
Voss Water Is Bullshit
Bad Cop Blotter: The Police Aren't So Brave When Someone Has a Weapon
It's a Godlis World: Early Photos of Punk Rock After Dark
VICE News: Water War: Dry in Detroit
Tim and Eric Tell Us About Their Greatest Fears
We Asked a War Correspondent About the Origins of ISIS


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Dover News
Local news for Dover, OH continually updated from thousands of sources on the web.
Sunday Aug 24 | Examiner.com
Breitenbach Winery will be going to the dogs at their annual Fun Dog Show
If you are a dog lover and a fan of wine, here is the perfect event to combine both of your interests.
Notebooks And Pencils And Pens, Cha-Ching
Millions of families are heading to Target or Wal-Mart this month to make sure their kids have what they need for the first day of school.
Body recovered from Tuscarawas River in Coshocton County
Authorities in Tuscarawas and Coshocton counties have confirmed that a body has been recovered from the Tuscarawas River but have not confirmed the identity.
Saundra "Sue" DeLancey, 61, of Rock Run, St. Marys, wife of Allen DeLancey, went to be with the Lord, Wednesday, Aug. 13, 2014.
17-year-old missing after last seen in the Tuscarawas River
Dive teams from various nearby fire departments continued the search Monday for a 17-year old male who possibly drowned in the Tuscarawas River Sunday afternoon.
Rocky River girls plan to cut their locks and aid others: West Shore Chatter
Seven Rocky River youngsters will be getting a new look just in time for the start of the school year.
They're Back: 100 holes for charity
WTOV9.com DOVER, Ohio -- Last year, Nathan Stambaugh and Josh Carlisle completed a 100-hole hike to raise money for Big Brothers Big Sisters.
Dover News, Events & Info
Updated: Sun Aug 24, 2014 06:43 am
Copyright © 2014 Topix LLC


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The Bolton News
All the latest news from Bolton
Third person charged in connection with Marc Jepson death (From The Bolton News)
Third person charged in connection with Marc Jepson death
Updated 4:43pm Thursday 20th March 2014 in News By Jeremy Culley, reporter
DETECTIVES investigating the death of Marc Jepson in Farnworth have charged a third man in connection with the incident.
Vikas Hussain, aged 25, of Leverhulme Avenue, Great Lever, has been charged with perverting the course of justice.
He has been remanded in custody to appear at Bolton Magistrates Court today.
Carl Hodgkiss, aged 28, of Elton Avenue, Farnworth, has previously been charged with Mr Jepson's murder, and will stand trial in August.
Irene Hodgkiss, aged 63, of Firwood Avenue, Farnworth, has been charged with assisting an offender.
Mr Jepson, aged 40, was found dead at his home in Kildare Street, Farnorth, on Wednesday, March 5.


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Zurich Restaurants
Zeughauskeller Review
Built as an arsenal in 1487, this enormous stone-and-beam hall offers hearty meat platters and a variety of beers and wines in comfortable Germanic chaos. The waitstaff is harried and brisk, especially at lunchtime, when crowds are thick. Unlike the shabbier beer halls in Niederdorf, this one is clean and bourgeois, reflecting its Paradeplatz location. They're not unaccustomed to tourists—menus are posted in English, Japanese, and at least 10 other languages—but locals consider this their home away from home.
- Address: Bahnhofstr. 28, at Paradepl., Kreis 1, Zürich, 8001 | Map It
- Phone: 044/2201515
- Website: www.zeughauskeller.ch
- Location: Left Bank: The Altstadt
Contact Information
- Credit cards accepted.
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Old Salt Union to Release The Bridge
By Christian Schaeffer
Emcee Classiq Sounds Off on ferguson
By Gabriel San Roman
By Chaz Kangas
Local Creatives Get Behind Ferguson
By Allison Babka
Bruiser Queen Signs to Boxing Clever
By Bob McMahon
Bo & Co. Posed for National Stage
By Allison Babka
6 Tips for Independent Musicians
By Tef Poe
The Grove's Got Some Growing Pains
By Mabel Suen
2100 Locust St.
St. Louis, MO 63103
Category: Bars and Clubs
Region: St. Louis - Downtown
Shannon McNally lists Bob Dylan, Neil Young and author Cormac McCarthy among her influences, but hers is no country-rock for old men. The Long Island native has done time in LA, New Orleans and now lives in Oxford, Mississippi. These nomadic travels show up in her songs: McNally's latest, Coldwater, shows traces of Laurel Canyon folk, front-porch blues and gospel-tinged balladry. Her voice carries a seductive drawl, like a more forceful Gillian Welch, but she knows when to pull her punches and when to unleash a haymaker. Coldwater was recorded with the late Jim Dickinson and features her backing band Hot Sauce, which will join her for the inaugural night of Twangfest 2010. Big Smith and Colonel Ford will also perform.


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Spent 5 nights here July 2014. Decent room. A/C worked fine, which is important in Texas in the summer. Beds are a bit stiff. Pretty clean, satisfied overall. No pool, which would've been nice for the kids. Wi-Fi worked fine, but good 4G signal in area as well. Very conveniently located to local grocery and Wal-Mart. Easy to get to... More
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- Also Known As:
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- Killeen Sleep Inn


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Project Color Corps first annual fundraising event.100 artists explore color for community change.
Project Color Corps presents Art for HUemanity$10
Fouladi Projects is excited to host Project Color Corps first annual fundraising event - Art for HUEmanity. This one night event features artwork for auction from nearly 100 artists – working in a range of mediums from painting, photography, ceramics and mixed media - exploring the power of color as catalyst.
Twenty-five of the featured artists are represented at Fouladi Projects, including four whose art works are intriguing conversation starters: Lisa Solomon, Anne Veraldi, Karen Barbour and Matt Gonzales.
We will request a $10 donation at the door. Your contributions provide direct and critical support for Project Color Corps' program and make it possible to transform communities through paint and pattern.
Refreshments and appetizers will be served.
Please RSVP to email@example.com
learn more about the project here: www.projectcolorcorps.org


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Business Card Designer Plus 184.108.40.206 download by CAM Development
Business Card Designer Plus allows you to create stunning business cards on any Windows compatible printer. With this software you can create your own business cards in literally seconds. It is ...
type: Shareware ($29.95)View Details Download
categories: business card, bizcard, card, print, graphic, design, webcard, cd-r
Label Designer Plus DELUXE 220.127.116.11 download by CAM Development
A single, powerful product for all your labeling needs! Label Designer Plus DELUXE allows you to create great looking Address and Shipping Labels, CD and DVD Labels and Inserts, Envelopes, Post ...
type: Shareware ($39.95)View Details Download
categories: label, envelope, post card, DVD, jewel case, sign, print, office, graphic, design
Print Designer GOLD 184.108.40.206 download by CAM Development
A single, powerful product for all your printing needs! Print Designer GOLD allows you to create great looking Business Cards, Address and Shipping Labels, CD and DVD Labels and Inserts, Envelopes, ...
type: Shareware ($59.95)View Details Download
categories: business card, label, envelope, post card, DVD, jewel case, sign, print, office, graphic, design
Wartungsplaner v6 6.00.733 download by GBelectronics GmbH
... version. These new ideas were relevant for the development and so we made a complete work for every kind of company. The software is usable for small business as well ...
type: Demo ($119.00)View Details Download
categories: Maintenance, Wartungsplaner, Servicing, Certification, certificate, DIN ISO 9001, Repairs, Malfunction, Life cycle, Archive, Maintenance work, Interval, Time table, Calendar weeks, Shifted work, Counter reading
Winlog Lite 2.06.82 download by Sielco Sistemi
... supervision of industrial and civil plants. An integrated development environment provides different tools (Gate Builder, Template Builder, Code Builder) for the easy and intuitive creation of multilanguage applications. Communication with ...
type: Freeware ($65.00)View Details Download
categories: scada, hmi, opc, system, data acquisition, industrial, supervisory, communication, software, modbus, siemens, omron, free, freeware
Vitrine multimedia, Digital signage free V2.39 download by BnetP
... manage your agencies, your points of sale) - DEVELOPMENT PERSONALIZED (compatibility possible with your real estate transaction software, your website, etc.). - Suitable for all types of existing (Change of ...
type: FreewareView Details Download
categories: Digital signage, Interactive Kiosks, Digital Advertising, Digital Information, Electronic Display Networks, Interactive signage, Electronic Poster, Dynamic signage, software storefront, Lcd showcase showcase multimedia showcase virtual showroom, mult
PHPFABER Online Website Builder and CMS 2.4.0 download by PHPFABER - website design & development
PHPFABER CMS is a PHP-based content management system with integrated phpbb forum. PHPFABER CMS delivers on the promise of separating content from code and frees your organization to focus on content. ...
type: Commercial ($49.95)View Details Download
categories: content management, links indexing, user authentification, portal, paid membership, cms, content, wysiwyg editor, online webbuilder
PHPFABER FeedExtractor 1.6.2 download by PHPFABER - website design & development
PHPFABER FeedExtractor allows you to do RSS into HTML converting as easy as possible. Using this script you can convert RSS feeds into HTML pages and store them on your website ...View Details Download
PHPFABER TopSites 3.6 download by PHPFABER - website design & development
PHPFABER TopSites is a feature-packed, reliable and secure Top List coded in PHP and mySQL. phpFaber TopSites has proven its reliability time and time again under the most active server environments. ...
type: FreewareView Details Download
categories: links indexing, content, website, internet, toplist, php, mysql, site, company, business, services, products, web, list, top, topsites
UV Outliner 2.2 download by Ultraviolet Software
UV Outliner is a small and powerful application for creating, organizing, and collecting information. With UV Outliner you can create plans, schedules, and to-do lists, manage notes, collect and organize ideas, ...
type: FreewareView Details Download
categories: outliner, outlining software, notes management software, productivity, gtd
Numbering 2.01 download by Hard - Soft
... key generators is illegal and will prevent future development of Numbering Free Download Edition. ...
type: Shareware ($29.95)View Details Download
categories: Numbering, Software, Print, Merge, Numerator, Generator, Numeration, Tickets, Corel, Draw, Number, Numbering, Serial, Design, Designer
X-Cart Gold 4.3.0 download by Creative Development
Shopping cart software trusted by thousands of successful business owners worldwide. Web-based administrator area and installation wizard make setup and maintenance of the shopping cart as easy as point and click. ...
type: Trialware ($115.00)View Details Download
categories: open source code, online store, shopping cart software, store, shop, shopping cart
ChoiceAnalyst Standard 4.1 B4100 download by Catalyst Development Corporation
ChoiceAnalyst has nearly an infinite number of applications and is such a useful tool that it will be used in any application where decisions must be made. Its been said that ...
type: Trialware ($199.00)View Details Download
categories: decision making, rank choice, decision ranking, decision, planner, manager
K9 Koordinator Groomer Lite 6.0.294 download by K9 Bytes Software Inc.
... is a program with over 20 years of development and usage in the pet care industry. We, at K9 Bytes software, feel is important to show our longstanding and exemplary ...
type: Demo ($499.00)View Details Download
categories: pet resort management, manage pet daycare, pet resort POS, manage, management, POS
Easy Numbering 2.01 download by Hard - Soft
... key generators is illegal and will prevent future development of Easy Numbering Free Download Edition. ...
type: Shareware ($29.95)View Details Download
categories: Easy, Numbering, Software, Print, Merge, Numerator, Generator, Numeration, Tickets, Corel, Draw, Number, Numbering, Serial, Design, Designer
Hotel Booking System 2.6 download by hotelsystems.co.uk
... offline booking software solution. A lot of our development has been directed by our clients. We have found that clients want an easy and non-complicated piece of software that will ...
type: Shareware ($395.00)View Details Download
categories: hotel booking system, hotel booking software, booking system, booking software, room booking, online booking, online bookings
Prodiance Spreadsheet IQ 188.8.131.52 download by Prodiance
... or a consultancy with domain expertise in spreadsheet development best practices, Prodiance Spreadsheet IQ is the most comprehensive solution available, and an industry standard. Prodiance Spreadsheet IQ is a ...
type: Trialware ($995.00)View Details Download
categories: business, organiza, diagnostic, optimization, Excel
Video Rental Plus 5.40.05 download by Software Video Rental POS Ltd.
Video Rental Plus is a complete POS solution for Video Stores. Video Rental Plus allows you to keep track of all of your sales & rentals, keep a history of your ...
type: Shareware ($175.00)View Details Download
categories: Video Rental Software, Video Rental POS, Video Store Software, Video Store POS, Video Rental POS Software, Video Rental Point of Sale, DVD Rental Software, DVD Rental POS, DVD Rental Point of Sale, Program for Video Store, Movie Rental Software POS
Bonita Open Solution 6.3.1 download by BonitaSoft SA
... with your existing Information Systems No more special development effort required. Connect your Bonita Open Solution processes to your existing systems (databases, messaging, enterprise resource planning, enterprise content management, data ...
type: FreewareView Details Download
categories: Business Process Management, application development, business management, business process, management, manager
Centerprise Data Integrator Professional 188.8.131.52 download by Astera Software
... what it's all about! FEATURES: Integrated Development Environment: · Intuitive, clutter-free user interface that is ... featuring integration with version control to facilitate collaborative development Data Transformation: · Define complex data flows ...
type: Trialware ($2 999.00)View Details Download
categories: data integration, data integrator, data management, integration, integrator, IDE
Centerprise Data Integrator 18.104.22.168 download by Astera Software
... what it's all about! FEATURES: Integrated Development Environment: · Intuitive, clutter-free user interface that is ... featuring integration with version control to facilitate collaborative development Data Transformation: · Define complex data flows ...
type: Trialware ($999.00)View Details Download
categories: data integration, data integrator, data management, integration, integrator, management
TestTrack RM 2011.0.0 B18 download by Seapine Software, Inc.
... integrated ALM solution, TestTrack RM helps teams keep development projects on track by facilitating collaboration, automating traceability, ... SCM tools to provide end-to-end traceability of all development project artifacts. Enforce Regulatory Compliance: · TestTrack ...
type: TrialwareView Details Download
categories: requirement management, requirement lifecycle, requirement organizer, requirement, management, manager
Wheels4Deals 188.8.131.52 download by Wheels4deals
... for your dealership, but we also provide custom development to fit your business needs. We also provide on-site or online (using our remote access tools) training for your employee ...
type: Demo ($199.00)View Details Download
categories: Business Management, Car Lot Management, Car Dealer, Dealer, Business, Management
Talend Open Studio 5.6.0 r118307 M download by Talend Inc.
... data integration job design through an easy-to-use graphical development environment. It enables rapid deployment and reduces maintenance ... Designer, and Metadata Manager) within a single graphical development environment based on Eclipse, which is easily adapted ...
type: Open SourceView Details Download
categories: business modeler, job designer, metadata manager, modeler, designer, manager
Adaptrade Builder 1.1.1 download by Adaptrade Software
... strategies; complete code. Builder automates the strategy development process by generating and testing thousands of different strategies automatically using machine learning techniques to evolve strategies based on your performance ...
type: Trialware ($1 995.00)View Details Download
categories: trading strategy, TradeStation strategy, trading systems, trading, TradeStation, strategy
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|Software piracy is theft, using crack, warez passwords, patches, serial numbers, registration codes, key generator, keymaker or keygen for license key is illegal. The above development search results are freeware or software in full, demo and trial versions for free download. Download links are directly from our mirrors or publisher's website, development torrent files or shared files from rapidshare, yousendit or megaupload are not allowed!


text:
Gator Bytes
Tag: Renee Gork
SEC nonsense: Reporter fired for wearing Gators hat; Fake John Brantley tweets upset Florida
- 7:44 am Thursday, August 19th, 2010 by Jason Lieser
What's the SEC without ridiculous off-season news? Perfect for a day like this when there is no media access at Florida. No practice, either.


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Gelsenkirchen, Germany - Schalke forward Klaas-Jan Huntelaar will be sidelined for the remainder of 2013 because of a knee injury, Schalke manager Jens Keller said.
The 30-year-old Huntelaar has been battling a knee injury recently and had hoped to return to action this week for the Champions League clash with Chelsea on Tuesday.
But Huntelaar sustained a big setback this week as he limped out of training and the club has said that surgery is an option.
Keller has not yet revealed if the Netherlands international will undergo an operation, but he has said that Huntelaar will not available for the rest of 2013.
"It doesn't really matter what the decision is on Klaas-Jan Huntelaar," Keller said. "He can't play until Christmas. It doesn't matter if he decides to have an operation.
"He might recover without one. Both outcomes are possible. The decision has not been made yet."
Huntelaar has tallied two goals in two Bundesliga games this season.
Joined in studio w/Paul Desbaillets co-founder of annual soccer charity event GOAL MTL. We chat w/Susan Bell, Danny Smiles, UM02 Carlos & Heath Pearce
Fund Development Director of Tyndale St-George discusses GOAL MTL's legacy and the impact the funds raised have on her community
Runner Up in 2013's Top Chef Canada, Chef to the stars at Osheaga chats about why he actively supports and participates in GOAL MTL
TSN.ca is Canada's exclusive home to highlight and feature programs from the Barclay's Premier League. Check out the latest programs on VOD below.


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It's that time again. The time when Judy seems to turn on. You see most of the time mom is almost lethargic, sleeping about 16 hours a day. We try to keep her on a schedule but sometimes there's no getting her out of bed. It's like she powers down for months at a time and then out of the blue she reboots. ( sorry for the computer analogy but its the best way to describe the situation) This power burst can last for up to 72 hours. So I am grateful for the good night sleep I got last night.
I am usually a night owl. However last night I managed to go to bed early for a change. I was sleeping well. that is until 5:30 this mourning when my husband woke me to let me know that mom was up, and I knew I was in for a long day. By 8:30 am my mom and I had cleaned the kitchen and moped the floor. By 10:30 we had gone threw the motions of looking for a car that she no longer owns then giving her opinion on everything the girls from the view had to say. next we played hide the purse and shoes so mom had nothing to take with her when she "decided" it was time to leave. In between all of this I had to apologies to several strangers when my mother attempted to call my sister without knowing the phone number.
It is now 11:33am and I have finally talked Judy into taking a nap, even though I know this is a sad attempt to take a break because it wont last long. She will just lay in bed for a while without falling asleep. I would usually take this time to rest myself but with the before mentioned good night sleep plus the two cups of coffee this mourning I will just have to wait it out. I'm sure this story will be longer than usual so I will post it in sections. More to come. Stay tuned


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L.A. Artist Contemplates Future Traffic Flow, With Hot Wheels
timothy posted about 3 years ago | from the finally-a-reason-to-visit-los-angeles dept.118
John3 writes "American artist Chris Burden is finishing up his latest work titled Metropolis II for display this fall in Los Angeles. There's a fascinating five minute documentary on YouTube about his miniature city and the traffic that flows through it. He comments 'The idea that a car runs free, those days are about to close.' Whether you agree or disagree, he certainly has built one of the coolest Hot Wheels layouts I've ever seen."


text:
SOURCE: Scientific American
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How Mesopotamia Has Weathered the War
More than five and a half years into the Iraq War, the condition of archaeological sites and antiquities in Iraq remains a frustrating and contentious topic among archaeologists and art historians. Two surveys in the past year—one in northern Iraq in May, the other in the south in June—have persuaded some that the ongoing damage is far less extensive than most observers had believed. Yet with more than 10,000 registered sites and numerous other mounds of earth that may still conceal uncatalogued treasures from the "cradle of civilization," many archaeologists question whether the surveyed sites are representative of conditions elsewhere.
The report of the May survey, conducted by U.S. and Iraqi investigators, stated that "none of the sites showed signs of looting or extensive vandalism." Likewise, the June report, by a team of Iraqi and British archaeologists who visited eight southern sites, found little evidence of looting since the war began.
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- WWII Atomic Bomb Project Had More Than 1,500 "Leaks"
- Neanderthal 'Art' Found In Cave Sheds Surprising New Light On Ancient Intelligence
- Midterm Election Mind-Reading: The Market Tends to Win
- Proof surfaces for affair between Queen Victoria and her male assistant
- Could humans cause another Paleocene-Eocene Thermal Maximum?
- Marcus Rediker says it was pirates, slaves, and motley crews who shaped the modern world, not the big heroes we hear so much about
- Pro-Israel website chides Middle East Studies professors, claiming they're apologists for Hamas
- UCLA Economist, Known as Railroad Historian, Dies at 89
- David Rosand, an Art History Scholar Whose Heart Was in Venice, Dies at 75
- NYT interviews Rick Perlstein about his book


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Lobster Q is a fresh Seafood & BBQ Restaurant in Hampstead, NH offering Lobster, Swordfish, Haddock, Clam... more
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About the firewall rule, firewall setting, and intrusion prevention processing order
|Created: 2011-06-29
|Updated: 2011-12-20
|Article URL http://www.symantec.com/docs/HOWTO54968
Firewall rules are ordered sequentially, from highest to lowest priority, or from the top to bottom in the rules list. If the first rule does not specify how to handle a packet, the firewall inspects the second rule. This process continues until the firewall finds a match. After the firewall finds a match, the firewall takes the action that the rule specifies. Subsequent lower priority rules are not inspected. For example, if a rule that blocks all traffic is listed first, followed by a rule that allows all traffic, the client blocks all traffic.
You can order rules according to exclusivity. The most restrictive rules are evaluated first, and the most general rules are evaluated last. For example, you should place the rules that block traffic near the top of the rules list. The rules that are lower in the list might allow the traffic.
The Rules list contains a blue dividing line. The dividing line sets the priority of rules when a subgroup inherits rules from a parent group.
See Changing the order of firewall rules.
See How a firewall works.
Legacy ID
Article URL http://www.symantec.com/docs/HOWTO54968
Terms of use for this information are found in Legal Notices


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Wedding films by Bilski Productions will make you laugh, cry and bring back all the memories of your special day.
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Our wedding films are shot with an artistic eye and they range from 10-25 minutes in length.
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Restaurant - Indian in Hove
175 Church Road
East Sussex
Phone: 01273 7...
Similar nearby businesses
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The food alone is enough to have converted me to be a loyal customer of the Hove Tandoori, however the decor in the restaurant is classy and chic and often means what would have been 'a takeaway night' turns into an evening in the restaurant instead. Great Friendly service, great advise on the dishes, and very clean. No complaints at all here! Thank you all very much!
Lyndsey Cambridge - 07/07/2009
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