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More From Vermont Governor Jim Douglas
Vermont gets $50 million for high-speed rail
Posted by Equipment World Staff on Oct 01, 2010
Vermont has received $50 million in American Recovery and Reinvestment Act (ARRA) dollars to begin construction to improve 190 miles of ...
Do you want some tips to stay safe on the job site?
Equipment World has created an entire section devoted to safety.
Here are the most recent tips we've posted:
Hauling headaches: Know your load limits when trailering equipment
One-man machines: The operator should be the only person on a wheel loader


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Dean's Update - Recognizing Libraries' Staff
05/01/13 - 11:50:24 AM - Communications Office
For over fifty years, the American Library Association has sponsored observance of National Library Week during the month of April. This week celebrates the contributions of the nation's libraries and promotes their use. This month at Drexel, we focus on library staff, including librarians, archivists, support staff and professionals with diverse expertise in such areas as technologies, communications and fiscal controls.

subset: commoncrawl


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- Classifieds
- Carbondale Apartments
- About the DE
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- Archives
Bahamians dominate at Illini Classic
The SIU men and women's track team collected two event wins, both from jumpers, en route to a second-place finish Saturday at the Illini Classic. Bahamian natives junior Kenya Culmer and junior Dougie Palacious paced the Salukis with first-place finishes ... Continue Reading →
Throwers claim four titles in field events
With four top finishes and several notable performances, the Saluki field team took second place during the weekend's Illini Classic in Champaign. The meet featured teams from the University of Illinois Champaign, Western Kentucky University, Marquette ... Continue Reading →


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Expired Property Listing
This property is disabled.
Luxury Condo - North Naples - West of 41 in Naples
- bedrooms 2
- baths 2
- sleeps 6
- pool yes
- hot tub yes
- pets allowed no
- type Condo
- community Tarpon Cove
- rates (USD) $ 2,300 - $ 4,400 / month
vacation rental description
Enjoy a perfect vacation in Naples – Tennis, swimming, fishing,
water shuttle to Gulf beach, 4 pools, fitness center, country club
amenities – in our beautifully furnished 2 + den bedroom condo
located minutes from excellent golf, shopping, dining – all the
delightful activities Naples has to offer.
Overlooking a lake, our "Tommy Bahama Style" furnished home features
2 bedrooms plus den and a covered parking in a gated community with
3 pools and 38 acres of lakes and preserves on the Gulf of Mexico.
Membership to the Tarpon Cove Yacht & Racquet Club includes
waterfront clubhouse and pool, private dining, Tiki Bar with
Caribbean theme happy hours, sunset dinner cruises, marina, 8 tennis
courts, well-equipped fitness center, and water shuttle to secluded
Gulf shore beach at Wigging Pass.
Ideally located west of the US41, only minutes from airports, great
shopping and restaurants, and excellent golf courses.
condo rental amenities
This is a large second floor, corner unit, cathedral ceilings,
ceramic tile and new carpet in bedrooms, den and living room, south-
west exposure , views to private lake and preserve from living room,
master bed room and lanai. 2 Bedrooms (Master bedroom with King Size
Bed, 2nd Bedroom with 2 Twin Beds) Den with sofa/sleeper.
The fully equipped kitchen includes dishwasher, ice-maker and
microwave. The laundry room has washer and dryer. The cables TVs
have VCR and DVD.
All lines are included, Bedding Arrangement : 1 King, 1 Queen
Sofa/Sleeper, 2 Twins
- 1500 sqft - Low Rise Building
- Tommy Bahama style furnished - Covered Parking
- Western Exposure - 3 Swimming Pools
- Private corner unit - Use of Club Membership
- Secluded lake view - Large Swimming Pool in Club with
- Screened large Lanai Jacuzzi
- Full Kitchen - Air Conditioning
- Microwave - Ceiling Fans in all rooms
- Dishwasher - Stereo/CD Player
- Washer & Dryer - 3 Cable TV
- Various Appliances - VCR/DVD
- Large master bathroom
- Dual sink
activities and attractions in Naples Gulf Coast South
15-minutes to 5th Avenue shopping and the beautiful beaches of
25-minutes to Marco Island
55-60-minutes to Sanibal Island
45-minutes to Ft.Meyers Beaches
Local Activities and Attractions are:
- Golf - Fishing
- Health Club - Bicycling
- Snorkling - Dining
- Boating - Shopping
- Wind Surfing - Swimming
- Park - Tennis Court
- Water & Jet Skiing - Beach
- Scuba Diving - Beach Bars
vacation rental rates
January-February $ 4,000 / month
March $ 4,300 / month
April-November $ 3,300 / month
December $ 3,800 / month
9% Florida Tax
$100.00 condo association application fee
$750.00 Security Deposit (fully refundable after checkout if unit is
left in the same condition)
$100.00 Vacate Cleaning Fee
No refund if cancelled within 60 days of arrival date.
No smokers
Note: Until confirmed, prices are subject to change.


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Synth sequence with bent note properties. This sample has been used by the band Abandon All Ships. I am the original author. Thankyou
Roblox took this (and alot of other sound from this website)
dude best synth i ever heard
Abandon All Ships is one of my favorite bands, and when I heard this, I freaked out lol. Awesome sample!!!
Hey just coming back to post the link to the video i used this sound for. Hope you enjoy!
This is awesome! I was trying to find something just like this when i was trying to find some fun music for the end of a segment in a web series I'm working on. I'll post you a link to the video when it's up on youtube. Thanks so much for this!
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Dan Radcliffe: JKR says Dumbledore in "Deathly Hallows" was "Giving Me a lot of Trouble"Radcliffe Interviews
A second in depth interview with actor Dan Radcliffe is now online tonight, where the young actor discusses his role as Harry Potter as well as his performance in the upcoming production of "Equus.There are also some very interesting comments on a conversation Dan recounts that he had with author J.K.Rowling during a recent set visit while filming Harry Potter and the Order of the Phoenix, where the subject of writing Harry Potter and the Deathly Hallows was briefly discussed, and our beloved late Hogwarts Headmaster was mentioned. Full quotage from this new interview in The Observer is as follows:
"What does he think will happen in the final book? Will he die?
'I think I will. I sort of hope I will, really. I think that's really the only way Jo can end it, if Harry and Voldemort... Maybe one can only die if the other one dies. I don't know that for sure. But I'm quite looking forward to doing a death scene, if I get that opportunity.'
But honestly, he says, he has no idea of how the series will end. Nor does he want to. He's a Potter fan, like everyone else. 'Jo came down to the set at one point and I said, "Oh hello, why are you here today?" And she said, "Oh I just needed a break from the book - Dumbledore's giving me a lot of trouble." And I said, "But isn't he dead?" And she said, "Well, yeah, but it's more complex ..." I was like, [briskly] "OK, I'm not gonna ask anything else!"'
This lengthy interview also covers subjects such as his career, future films, a tad on the upcoming OotP film, and Dan also says Jo will be coming to see him in the production of "Equus," which begins previews next week in London.
"'She's coming to see it!' he says, beaming. 'She's very excited about it, which is great! I think it will be weird for her because - I'm not sure how true it is - someone said that when she first saw my screen test she said something about it being like she'd found the son she never had. So it's going to be very weird for her to see her long-lost son blind horses! I look forward to hearing what she thinks.'


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NY Times Position on Filibusters 'Evolves'... Again
In which the NY Times reveals itself, yet again, to be a simple, partisan rag...
In 2005, the Republicans in the United States Senate were frustrated by the Democrats' use of the filibuster to thwart Presidential nominations to the Federal judiciary, and were particularly concerned with the threat of a filibuster on Supreme Court nominees, which had never previously happened. Because of this, they contemplated a rule change to eliminate, or significantly limit, the filibuster, a change that was termed the "nuclear option." The mainstream press, as represented here by the New York Times, was appalled. This despite the fact that, with Democrats in the White House and control of the Senate, they had favored filibuster reform. No, they were just wrong earlier, and their new, more fully matured position, was the right one. Clearly, the filibuster was wrong. A problem.
March 29, 2005 - Walking in the Opposition's Shoes
While the filibuster has not traditionally been used to stop judicial confirmations, it seems to us this is a matter in which it's most important that a large minority of senators has a limited right of veto. Once confirmed, judges can serve for life and will remain on the bench long after Mr. Bush leaves the White House. And there are few responsibilities given to the executive and the legislature that are more important than choosing the members of the third co-equal branch of government. The Senate has an obligation to do everything in its power to ensure the integrity of the process.
A decade ago, this page expressed support for tactics that would have gone even further than the "nuclear option" in eliminating the power of the filibuster. At the time, we had vivid memories of the difficulty that Senate Republicans had given much of Bill Clinton's early agenda. But we were still wrong. To see the filibuster fully, it's obviously a good idea to have to live on both sides of it. We hope acknowledging our own error may remind some wavering Republican senators that someday they, too, will be on the other side and in need of all the protections the Senate rules can provide.
On May 5, 2005, a little over a month later, they provided space on their editorial page to former Senator George Mitchell to make the same case against filibuster reform. Clearly, when the Democrats were in the minority, the filibuster was a vitally important tool for stopping the depredations of a Republican President and Senate. They recognized, at this time, the folly of their earlier position, that the filibuster was an archaic, anti-democratic nuisance, allowing Republicans to prevent the noble Democrats in the Senate and White House from getting done the vital work of the nation.
So, what goes around comes around. Again. As the editorial board has decided, again, that the principled (certainly not partisan or biased, but principled) position on the filibuster is that it must be reformed.
Fed up and rueful, Harry Reid, the Senate majority leader, made a startling admission on Thursday: he should have reined in the filibuster rule last year, when he had a chance...If Mr. Reid helped enact the proposal of [Senators Udall and Merkley], he would instantly make Congress more efficient and more democratic...We have supported eliminating the filibuster for judicial and executive nominees. Making other filibusters harder would be good for both parties. If Mr. Reid remains majority leader in January, he should lead the reform.
And, of course, they're not actually lying when they say that they "have supported eliminating the filibuster for judicial and executive nominees" - they're just conveniently omitting the fact that, when it was their guys doing the filibustering and not the other guys, it was A-OK with them.
Because it's not about principle. Never has been, never will be. The Times, despite its pretense to being a non-partisan purveyor of the news, is a partisan political actor. They are pro-Democrat, anti-Republican, leftist progressives and, to the extent that there's ever a "principle" behind their positions, that's the extent of it.
And it's been really obvious for a really long time. This was not hard to see coming, as this piece from 2006, during the "nuclear option" debate and the Alito nomination, demonstrates...
[I]f the Republicans don't change the rules, the Democrats will, as soon as it becomes in their best interest to do so. Is there any chance that a President Hillary Clinton nomination to the Supreme Court, a nominee with majority support in the Senate, could be kept off the court by a Republican minority with impunity? That a majority supported nominee could be filibustered without hysterical screeching from the legacy media? Of course not. The New York Times would compose frothy rants encouraging the Democrats to, for the good of the country, change the rules to overcome the obstructionists, so that they could back to the work of the American People...
- Lyford Beverage's blog
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Money Quote
Submitted by motherbelt on Tue, 05/15/2012 - 8:58am.
Because it's not about principle. Never has been, never will be. The Times, despite its pretense to being a non-partisan purveyor of the news, is a partisan political actor. They are pro-Democrat, anti-Republican, leftist progressives and, to the extent that there's ever a "principle" behind their positions, that's the extent of it.
It's all about whose ox is being gored.
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It's about supporting your
Submitted by texastommy on Tue, 05/15/2012 - 9:13am.
It's about supporting your political allies.
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Is this what it comes down to?
Submitted by DontFeedTheTrolls on Tue, 05/15/2012 - 11:11am.
In journalism school do they tell students that they have to pick one side, politically, and stick with it, right or wrong?
It sure looks that way.
Romney needs to reveal his whole past, plus his spouse's, his kid's and his friend's.
Obama can keep everything under lock and key.
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The New York Time position
Submitted by John21 on Tue, 05/15/2012 - 12:09pm.
The New York Time position will always evolve around what is best at that moment for the liberal agenda and the Democratic party.
If those two entities do not benefit from any policy than it is terrible, if they benefit than it is wonderful. No surprise just their normal cheerrleading.
The New York Times bias is well recorded and provable the idea of honest fact based reporting is as foreign to them as speaking Klingon and has the same lack of integrety and reality base.
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Submitted by OldJarhead77 on Tue, 05/15/2012 - 12:31pm.
Wrapping their lips around the dims everyday.... all day... it never changes.
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Submitted by donabernathy on Tue, 05/15/2012 - 2:42pm.
Don't mind the thug'n as long as my guy is do'n da loot'n
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State Troopers arrested three people on Monday in Fayette County after a tip about an operational meth lab.
Ralph Bland, 36, Melinda Gwinn, 32, and Earnest Sorrells, 25, were arrested. The three are facing charges of possession of meth, attempt to operate a clandestine lab and conspiracy to commit a felony.
The lab was found by Troopers on Cowtown Road in Meadow Bridge. All three are being held in the Southern Regional Jail on $75,000 bond each.


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Home / How to Participate / Global Compact LEAD
In January 2011, the United Nations Global Compact launched a new platform for corporate sustainability leadership – Global Compact LEAD.
The approximately 50 companies that participate in Global Compact LEAD are challenged to implement the Blueprint for Corporate Sustainability Leadership, which was developed in close consultation with a large number of corporate participants and stakeholders and widely endorsed by business, governments, and civil society at the Leaders Summit in New York in June 2010.
The participants in LEAD have been invited because they have a history of engagement with the UN Global Compact – locally and/or globally. They have committed to work towards implementing the Blueprint and share related outcomes and learnings with the broader universe of companies in the Global Compact by participating in global initiatives as well as in Global Compact Local Networks. LEAD participants have also committed to address Blueprint implementation in the Communications on Progress (COPs).
Participation in Global Compact LEAD does not represent a "seal of approval" or endorsement by the United Nations. Rather, the platform is designed to challenge highly engaged companies in the UN Global Compact to reach further, to experiment, to innovate, and to share learnings – both successes and failures. Companies in LEAD will be organizations committed to leading new efforts to raise sustainability performance; membership in LEAD does not confer special status or imply a position of superiority with respect to individual participants.
This new platform is a reflection of the essential role that leading Global Compact participants have already played in the field of corporate responsibility and sustainability. At the same time, Global Compact LEAD responds to the critical need for leading companies to step up and reach new levels of performance and impact in order for the world to meet today's social, environmental and economic challenges.
Global Compact LEAD is deeply integrated into other UN Global Compact engagement opportunities – including, notably, the approximately 90 Global Compact Local Networks; the six global working groups as well as the Caring for Climate and CEO Water Mandate initiatives. Further, strong linkages will be built between Global Compact LEAD and the UN Agencies, Funds and Programmes collaborating with the private sector, as well as with the Global Compact's two sister initiatives – the Principles for Responsible Investment (PRI), and the Principles for Responsible Management Education (PRME).
The first two years of Global Compact LEAD (2011-2012) will be considered a pilot phase in order to allow for members of LEAD to help shape the platform and refine its services and programmes. The programmes and projects of LEAD, while aimed primarily at companies, will include the active involvement on non-business contributors, including UN entities, civil society organizations, academic institutions, and other interests. Review evaluation of Global Compact LEAD pilot phase.
LEAD News Archive
(Last Update 24 April 2013)


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This 1969 Jaguar is a 72,000 original mile example that has undergone an very comprehensive restoration. The Bonnet was removed engine bay strip of... More
1970 JAGUAR E-TYPE ROADSTER BEAUTIFULLY RESTORED! BELIEVED TO BE 20,106 ACTUAL MILES! UNDER SAME OWNERSHIP FOR THE PAST 24-YEARS! RARE FACTORY AIR CONDITIONING! MATCHING #'S ENGINE! FINISHED IN GORGEOUS FACTORY-CORRECT... More
1969 JAGUAR SERIES II E-TYPE ROADSTER BEAUTIFULLY RESTORED AND MAINTAINED! RARE FACTORY AIR CONDITIONING! HIGHLY DESIRABLE 4-SPEED MANUAL TRANSMISSION! GORGEOUS CHROME WIRE WHEELS! FINISHED IN DESIRABLE PRIMROSE WITH BLACK... More
1966 Jaguar E-Type Series I 4.2 RoadsterTo be OFFERED AT AUCTION at Auctions America's Auburn Fall event, August 27-31, 2014. Click here to view... More
1974 Jaguar E-Type Series III V-12 RoadsterTo be OFFERED AT AUCTION at Auctions America's Auburn Fall event, August 27-31, 2014. Click here to view... More
TO BE SOLD AT THE UPCOMING LUCKY COLLECTOR CAR AUCTION FALL CLASSIC AUCTION Lot 478: 1973 Jaguar XKE Series III VIN: VDIS21532 I have owned the car... More
Launched at the 1961 Geneva Motor Show, the Jaguar E-Type was nothing short of a revelation. With its heady blend of supercar performance, breathtaking... More
MotorCarTrader.com, LLC is proud to offer this gorgeous 1973 Jaguar E-type roadster. This car has low original miles on 41,622. It is the original... More
Beautiful 1969 Jagaur XKE Coupe painted in correct British Racing Green.Many modifications performed for the intention of making this Jaguar a reliable driver. Paint... More
1970 Jaguar E-Type (XKE) Roadster Series II, manual transmission. This is the car every guy wants - "The most beautiful car in the world,"... More
1967 Jaguar E-Type Series 1 4.2 Liter Roadster, We have been the owner of this beautiful Series 1 XKE for 31 years. The car... More
Brighton Motorsports is very pleased to present this 1962 Jaguar E Type Coupe This Car has undergone a full nut and bolt restoration by "Classic Showcase" Car is stunning! Finished... More
1968 JAGUAR SERIES 1.5 E-TYPE COUPE JUST COMPLETED BEAUTIFUL RESTORATION, INCLUDING SHOW QUALITY PAINT, CORRECT LEATHER INTERIOR AND OVER $11,000 IN RECEIPTS FROM MECHANICALS AND... More
This very original San Diego V12 2+2 has a California title, and has been restored by a prominent Jaguar restorer. It comes complete with... More
Jaguar Rancho Mirage and indiGO Classic Cars proudly offer this magnificent, fully restored 1965 Jaguar E-Type (XK-E) FHC (Fixed Head Coupe) 4.2L Series I. ... More


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3 BEDROOM, den plus mud room, 1 ba. $795 mo. plus deposit. No calls after 8 p.m., 503 728-3822 or 360 749-2234. 1-13-tfc
STORAGE – STORAGE Quality, Affordable Storage. Big, little, small. Clatskanie Mini Storage. 503 728-2051. 4-10-tfc
RENTS FROM $550-$650, 2-3 bdrm. MH, w/s/g paid. Western Hills Mobile Home Estates, 74866 Doan Road, Rainier. 5-6-tfc
1 BDRM. APARTMENTS for rent. Water and garbage paid, downtown. No pets, 503 728-2409. 6-10-tfc
ROOMY 2 BD. HOUSE with partial basement on Nehalem Street. Large appl. furnished, 1 yr. min. No pets, no smoking, 503 728-2263. 8-26-tfc
FOR RENT – CREW HOUSE in town, 4 bdrm., 1 ba., w/d hookup, furnished, $995 mo., $500 deposit, 503 728-1669. 11-11-tfc
HOME FOR RENT- Westport Heights, 3 bedroom, large garage. $750 a month. First and last plus $500 deposit. Call 503 728-3047 after 6 p.m. 1-20-tfc
FOR RENT: 2 bdrm. trailer, Section 8 accepted, $550 per month plus security deposit. Call Teri at 503 369-9340 to set up viewing 2-3-tfc
RENTAL: 1 bedroom, downstairs apartment for rent. Quiet country setting with a great view. No smoking, No dogs. Dish available-will split bill. $425 mo., plus deposit. 503 728-3263. 3-3-c
RAINIER RIVERFRONT: furnished studio, cable and utilites paid, $365 mo., 503 556-8100. 2-10-tfc
RENTALS Westport: Two-story home with great view of Columbia River. Lg. upper deck to relax on. 2 bed., 2 bath, lg. living room. Gated community. $800 per month.
Columbia City: Two bed., upper unit duplex. Great condition. Laundry room. River views from a covered deck. $650 per month.
Columbia City: One bed., 1 bath lower unit with covered parking. Lg. kitchen, patio. $500 per month.
Rainier: Two bed., 2.5 bath home. Newer riverfront home with viewing deck off master bedroom. Walking distance to the beach and fishing. Attached garage. $1000 per month.
Rainier: Large two-level 2080 sq. ft. home offering 4 possibly 5 bedrooms, detached garage. 1.25 acres to enjoy. $1150 per month.
Call Jenny Erhardt
Principal Broker,
Property Manager
503 987-1429
or cell 503 260-5450
52696 NE 1st.
Scappoose, Ore.
CLATSKANIE MINI STORAGE Heated and non-heated units. Surround insulation. 20 sizes starting at $12 a month. Free use of handtrucks, piano dollies. Storage supplies for sale. On-site manager. Fenced. Long-term storage discounts. 503 728-2051. Visa/MC. 8-6-tfc
503 556-1117
I DO WEDDINGS! select your vows from my collection or write your own. I'll help you make your wedding day as special as you want it to be. 503 397-5868. 5-24-tfc
PRUNING BY THE BID, evergreens, deciduous, Vern LaPier, 503 728-4605, references, license. 2-24-pd
ADULT CARE PROVIDED: Experienced caregiver/NAR. Reliable, caring, compassionate, in your own home care. Excellent reference. Call Kathy at 503 728-3263. 3-3-c
INTERVIEWING & HIRING NOW- part-time or full-time. Deli, cashier or gas attendant. Application available at West Mart Foods, Westport, or call 503-455-2253. 1-1-tfc
NOW HIRING Direct Care Temporary full staff wanted to work in a 5-bed group home providing support to individuals with developmental disabilities in Clatskanie, Ore. Preference is given to those with experience working in social services or the caregiving field and able to qualify as a company driver. Applicants must be able to pass a criminal history check and pre-employment drug screen. Position starts at $10-$10.25 per hour DOE plus benefits. Call Jan at 503 728-2435. Community Access Service a drug free work place/equal opportunity employer. 2-24-c
ELDER-LIVE IN OPENING: We have one opening for private pay resident in our home, 24-hour care by a certified medical assistant. Country home with horses, chickens, fenced property. Plenty of property to roam around on, nice comfortable home, home-cooked meals. References and background check upon request. For more info call 503 396-0384, Roberta. Rainier/Clatskanie area. 2-24-c
PARK HOST: Columbia County, Ore. See website for details, www.co.columbia.or.us. Columbia County Parks, 1054 Oregon St., St. Helens, OR 97051, phone 503 397-2353. Deadline: open recruitment. EOE. 2-24-c
M & M RECYCLING Will pay cash for cars, trucks, yard and farm equipment. Brass, copper and batteries. Titles not required. 503 739-0442. 1-27-tfc
Columbia County Anonymous Drug Tip Line:
GOOD QUALITY GRASS HAY, $4.25 bale. 503 556-2261 or 503 556-9591. 2-24-pd
Call 503 728-3350 or
e-mail firstname.lastname@example.com
LOST: Blue blanket with picture of eagle, $50 reward, 503 728-2645. 2-24-pd
NICE TRUNDLE BED with two twin mattresses, white decor metal. Non-smoking home, $100. 503 728-2920. 2-24-pd
4-PIECE BROYHILL living room set, $300. 503 728-4942. 2-24-pd
Comments are closed.


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Welcome to the Gameday Open Thread at Blazer's Edge! This is a place to hang out and enjoy tonight's festivities with your fellow fans. Treat it as if you're watching a game at the local watering hole, but hopefully without the language. Expect some disagreements, and a fair amount of changing emotions. But we'll get through it together.
Watch: NBA League Pass CSN NW
Listen: NBA Audio League Pass 620am
Links: Media Notes Viewing Guide Updates on Twitter
The Blazers are expected to be at full strength tonight. Check here for any last-minute injury updates.
The usual Gameday Thread rules apply:
1. No swearing
2. No pictures
3. No discussion of unlicensed Internet streaming
4. Be cool to each other!
Hang out and enjoy the game! -- Tim


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Jim Mallinder: 'Of course we could have won'
The Saints' Director of Rugby took plenty of positives from his team's showdown with Quins.
(01:46) | May 4, 2013
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Aviva Premiership: Leicester beat Northampton to secure the Aviva Premiership Title 2013
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Geordan Murphy: I'm really proud
Aviva Premiership: Geordan Murphy praises his side after his final involvement as a Leicester Tigers player and is congratulated in a suitable style!
(01:47) | May 25, 2013
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Cleverley seals loan move to Aston Villa
Premier League: Aston Villa have completed the loan signing of Manchester United midfielder Tom Cleverley after the Premier League ratified the transfer.
(01:21) | Sep 2, 2014
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Alves to leave Barcelona in 2015
La Liga: Barcelona sporting director Andoni Zubizarreta has confirmed Dani Alves will leave Barcelona when his contract expires at the end of the 2014-15 season.
(01:07) | Sep 2, 2014
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Deschamps: French may stick or twist
International Football: Didier Deschamps admits he may try new things in France's friendly against Spain on Thursday, as he looks to build on an encouraging World Cup.
(01:40) | Sep 2, 2014
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International Football: Head Coach Joachim Loew has announced Bastian Schweinsteiger as his new captain and says the team's next target is the Euro 2016 final in Paris.
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Djokovic and Murray set up quarter-final clash
Tennis Video: Novak Djokovic reached his 22nd consecutive grand slam quarter-final at the US Open and will face Andy Murray, who defeated Jo-Wilfried Tsonga in New York.
(01:54) | Sep 2, 2014
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Conte leaves Balotelli out of first squad
International Football: Italy head coach Antonio Conte insists he is not trying to send a message to Mario Balotelli after leaving the 24-year-old out of his first squad.
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How many times have the Springboks Tendai Mtawarira and Bismarck and Jannie du Plessis started as South Africa's Test front-row?
'Dai Ding Dong'
Which Welsh rugby player was known as "Dai Ding Dong"?


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All graduates are invited to attend various student organization sponsored events at the Law School throughout the year. These programs are wonderful networking opportunities for both students and graduates.
Please check back frequently for updated listings.
March 6, 2014
7:00 pm
Feil Hall, 250 State Street, Brooklyn, NY
On March 6, we will be holding the 24th Annual BLSPI Auction. The evening includes both a live and silent auction. Items up for bid have included everything from sports tickets and memorabilia to gift certificates for great area restaurants, networking and social opportunities with our law school faculty, artwork and jewelry donated by local businesses, and even the chance to share a meal with some of Brooklyn Law School's most famous alumni, including Geraldo Rivera. And, of course, all attendees will be able to partake in complimentary appetizers and hors d'oeuvres and enjoy an open beer and wine bar.
The money we raise will fund BLSPI's numerous public interest initiatives, all of which are designed to improve the lives of people in need. One of the principal initiatives made possible by the auction is the BLSPI Fellowship Program. Each year, we give out summer fellowships to 20 deserving and dedicated students, allowing them to take on public interest legal positions that would otherwise be unpaid.
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We hope to see you in March!
View photos of the 2013 BLSPI Auction.
BLSPI is a student-run, non-profit organization that encourages and enables student participation in public interest legal positions. Hundreds of students, alumni, and professors attend the auction and bid on donations every year.
All money raised at the auction directly funds BLSPI initiatives, including academic presentations, clothing and food drives, and community service trips. Most importantly, auction proceeds help fund the Annual BLSPI Summer Fellowship Program, one of the most prestigious awards at Brooklyn Law School. Each fellowship provides a stipend that allows a student to work in a summer internship that would otherwise be unpaid. BLSPI Fellows have a direct impact on our local, national, and international communities.
View photos from some recent Student Organization Alumni Events: APALSA Alumni Dinner, LALSA Alumni Dinner & IALSA Alumni Dinner.
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text:
hello all,
Initially i started learning from agile web development with rails and then i thought of learning ruby first so i switched to PickAxe book. But i am finding pickAxe book very much difficult(although i was good at c++ programming). please suggest me that from where should i learn it now. online videos, or any reference links.
also i would like to ask should i learn ruby deeply for learning rails?


text:
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31. Endogenous testosterone, fibrinolysis, and coronary heart disease risk in hyperlipidemic men. Glueck CJ, Glueck HI, Stroop D, Speirs J, Hamer T, Tracy T Department of Pathology, University of Cincinnati College of Medicine. J Lab Clin Med 1993 Oct;122(4):412-20
To assess relationships of endogenous testosterone with fibrinolysis and coronary heart disease risk factors in 55 newly referred hyperlipidemic men, we studied the relationships of testosterone to basal fibrinolytic activity, lipids, lipoproteins, and apolipoproteins. Testosterone correlated positively with the major stimulator of fibrinolysis, tissue plasminogen activator activity (r = 0.30; p = 0.02) and correlated inversely with two independent coronary heart disease risk factors, plasminogen activator inhibitor activity, the major fibrinolysis inhibitor (r = -0.33; p = 0.01), and fibrinogen (r = -0.39; p = 0.004). Testosterone correlated inversely with plasma triglycerides (r = -0.33; p = 0.01). Stepwise multiple regression was done with fibrinolytic activities as the dependent variables, and age, Quetelet Index (relative ponderosity), apolipoprotein A-I, apolipoprotein B, triglyceride, testosterone, time of blood sampling, and lipoprotein (a) as explanatory variables. Testosterone was an inverse, independent predictor of fibrinogen (p = 0.002); 53% of the variance of fibrinogen could be accounted for by age and triglyceride level (positive; p = 0.001, p = 0.01), and by apolipoprotein A-I and testosterone (negative; p = 0.02, p = 0.002). Testosterone was an independent inverse predictor of tissue plasminogen activator antigen (p = 0.0008), with tissue plasminogen activator antigen correlating inversely with tissue plasminogen activator activity. Quetelet index and apolipoprotein B wereindependent negative predictors of tissue plasminogen activator activity (p =0.02, p = 0.03); Quetelet index and triglycerides were independent positive predictors of plasminogen activator inhibitor activity (p = .0001, p = .0001) and alpha 2-antiplasmin (p = 0.0003, p = 0.009).
32. Effects of androgens on haemostasis. Winkler UH Zentrum fur Frauenheilkunde, Universitatsklinikum Essen, Germany. Maturitas 1996 Jul;24(3):147-55
Androgen deficiency is associated with an increased incidence of cardiovascular disease. There is evidence that thromboembolic disease as well as myocardial ifarction in hypogonadic males are mediated by low baseline fibrinolytic activity. Hypogonadism in males is associated with an enhancement of fibrinolytic inhibition via increased synthesis of the plasminogen activator inhibitor PAI 1. On the other hand, stanozolol and danazol reduce PAI 1 and are associated with increased fibrinolytic activity. However, in male abusers of anabolic steroids the net effect on the haemostatic system may change from anti- to prothrombotic; there appears to be an individual threshold dose above which thrombogenic effects on platelets and vasomotion may overcome the profibrinolytic effects on PAI 1. There are numerous reports on weight-lifters dying of atherothrombotic ischemic heart disease while abusing anabolic steroids. Androgens are known to have profound effects on carbohydrate and lipid metabolism. In fact, much of the individual inconsistency of the effects of androgens on fibrinolytic and haemostatic activity appears to be based on the close interrelationship of these metabolic systems. Androgens may have unfavourable effects on the HDL/LDL cholesterol ratio, on triglyceride levels and on the insulin/insulin-like growth factor 1 (IGF 1) system. Hypertriglyceridemia as well as insulin resistance are both associated with low fibrinolytic activity and increased PAI 1 levels. On the other hand, lipoprotein(a), a recently acknowledged independent risk factor of CVD was shown to respond favourable to androgen treatment, in men as well as in women. In women, agonistic as well as antagonistic effects of estrogens and progestins need to be taken into account. In fact, estradiol may modulate testosterone effects on haemostasis. Androgen medication in premenopausal women, such asdanazol, was found to reduce PAI 1 suggesting an improvement of the fibrinolytic activity. Also, in hormone replacement therapy (HRT) androgenic progestins or complex compounds with androgenic effects are associated with a marked reduction of PAI 1 and an improvement of fibrinolytic activity. Further improvement of fibrinolytic activity may be associated with the marked decrease of lipoprotein (a) (Lp(a)) in women on androgenic HRT. However, little is known on the interrelationship of estrogens, 19-nortestosterone or progesterone derivatives and testosterone. an interrelationship that may have substantial impact on the metabolic and particularly haemostatic net effects of a preparation. In summary, information on the effects of androgens on haemostasis is limited and may be particularly incomplete due to the fact that interaction with other sex steroids appears to be an important confounder. In any case, there are numerous effects of synthetic androgens on the synthesis and release of haemostatic factors, namely an increase of the inhibitors of coagulation and a decrease of the inhibitor of the fibrinolytic system. However, the use of androgens in patients with congenital deficiencies of these coagulation factors or previous events of cardiovascular disease has yielded disappointing results. On the other hand, particularly the reduction of fibrinolytic inhibition (PAI 1) and Lp(a) were considered favourable effects of androgens with regard to the risk of cardiovascular disease. Differences between preparations withpronounced androgenic versus antiandrogenic effects and the effect of combined preparations need to be studied in much more detail. The profibrinolytic effects of androgens may be of particular interest with regard to favourable effects of HRT on cardiovascular disease.
33. Plasminogen activator inhibitor in plasma is related to testosterone in men. Caron P, Bennet A, Camare R, Louvet JP, Boneu B, Sie P Service d'Endocrinologie, Hopital Purpan, Toulouse, France. Metabolism 1989 Oct;38(10):1010-5
Low plasma testosterone and high levels of the rapid inhibitor of plasminogen activator (PA-I) have been proposed as risk factors for myocardial infarction. In this study, the relationship between testosterone and PA-I activity levels in middle-aged men without thrombotic antecedent was investigated. In 54 normogonadic men (testosterone, 7.3 to 29.1 nmol/L), PA-I was related positively to body mass index (BMI) and triglycerides and negatively to testosterone. When these variables were controlled, the relation between PA-I and testosterone remained significant (P less than .01). In the 41 normogonadic men with BMI less than 25, testosterone was the only variable to influence PA-I. Fibrinolytic activity was evaluated by the euglobulin lysis plate method and the specific measurement of functional tissue plasminogen activator. The basal fibrinolytic activity and the response to venous occlusion were essentially controlled by PA-I but were not significantly related to testosterone. In 17 men with severe hypogonadotrophinic hypogonadism (testosterone less than 3 nmol/L), PA-I was significantly increased (18.5 +/- 1.8 AU/mL, mean +/- SE) compared with 9.5 +/- 0.8 AU/mL in 41 normogonadic men of normal weight (P less than .001). However, 14 hypogonadic men had a hypertriglyceridemia or a BMI greater than 25, which could explain high PA-I levels. This study shows that the level of the inhibitor of plasminogen activator is partly dependent on hormonal status in men and provides a link between independently established epidemiologic data.
34. Testosterone increases human platelet thromboxane A2 receptor density and aggregation responses Ajayi AA; Mathur R; Halushka PV Department of Pharmacology, Medical University of South Carolina, Charleston 29425-2251, USA. Circulation (United States) Jun 1 1995, 91 (11) p2742-7
BACKGROUND: The incidence of thrombotic cardiovascular disease is greater in men than in premenopausal women. Testosterone has been implicated as a significant risk factor for cardiovascular disease and for acutemyocardial infarctions and strokes in young male athletes who abuse anabolic steroids. Thromboxane A2 (TXA2) is a vasoconstrictor and platelet proaggregatory agent that has been implicated in the pathogenesis of cardiovascular disease. We therefore tested the hypothesis that testosterone regulates the expression of human platelet TXA2 receptors.
METHODS AND RESULTS: In a double-blind, placebo-controlled, randomized, parallel-group study, we determined the effects of testosterone cypionate 200 mg IM given twice, 2 weeks apart, or saline placebo in 16 healthy men. Platelet TXA2 receptor density (Bmax) and dissociation constant (Kd) were measured by use of the TXA2 mimetic 125I-BOP. Platelet aggregation responses to I-BOP and to thrombin and plasma testosterone concentrations were measured before treatment (pretreatment phase), at 2 and 4 weeks (active phase), and again at 8 weeks (recovery phase). Treatment with testosterone was associated with an increase in the Bmax value from 0.95 +/- 0.13 to 2.10 +/- 0.4 pmol/mg protein (n = 9), with a peak effect at 4 weeks (P = .001), returning to baseline by 8 weeks. There was no significant change in Bmax values in the saline-treated group. The Kd values were unchanged. Testosterone treatment was associated with a significant increase in the maximum platelet aggregation response to I-BOP (P < .001) at 4 weeks and returned to baseline at 8 weeks. The EC50 values were not significantly changed. Platelet TXA2 receptor density was positively correlated (r = .56, P < .001, n = 32 measurements) with pretreatment (endogenous) plasma testosterone levels (range, 215 to 883 ng/dL) but not Kd.
CONCLUSIONS: Testosterone regulates the expression of platelet TXA2 receptors in humans. This may contribute to the thrombogenicity of androgenic steroids.
35. Endocrine environment of benign prostatic hyperplasia: prostate size and volume are correlated with serum estrogen concentration. Suzuki K, Ito K, Ichinose Y, Kurokawa K, Suzuki T, Imai K, Yamanaka H, Honma S Department of Urology, School of Medicine, Gunma University, Japan. Scand J Urol Nephrol 1995 Mar;29(1):65-8
Estrogen plays an important role in the development of benign prostatic hyperplasia (BPH), as has been shown in both experimental and clinical studies. T determine the endocrine environment of BPH, serum total testosterone (Total-T), free testosterone (Free-T), and estradiol (E2) conceptions were measured, and the relationship between these levels and prostate size and volume was analyzed. Blood samples were collected from subjects who attended the mass screening for prostate disease performed by our institute. No significant correlations were found between Total-T levels, Free-T levels, and prostate size, as determined by digital rectal examination. However, E2 levels and the ratios for E2 levels and the ratios for E2/Total-T and E2/Free-T were significantly correlated with prostate size. To confirm these relationships, prostate volume was calculated from transrectal ultrasonographic images. E2 levels and these two ratios were, indeed, highly correlated with prostate volume. These results suggest that an estrogen-dominant environment plays an important role in the development of BPH.
36. A prospective study of plasma hormone levels, nonhormonal factors, and development of benign prostatic hyperplasia. Gann PH, Hennekens CH, Longcope C, Verhoek-Oftedahl W, Grodstein F, Stampfer MJ Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Prostate 1995 Jan;26(1):40-9
We assessed the relation of plasma hormone levels and nonhormonal factors with subsequent occurrence of surgical treatment for benign prostatic hyperplasia (BPH) among participants in the Physicians' Health Study. Frozen plasma samples, collected at the study onset, were available for 320 men who developed surgically treated BPH up to 9 years later and for 320 age-matched controls. Plasma testosterone (T), dihydrotestosterone (DHT), androstenedione, estradiol (E2), and estrone (E1) were measured for each case-control pair. In unadjusted analyses, none of the hormones or hormone ratios were associated with BPH; for example, for T and E2 the odds ratios (OR) comparing the highest quintile (Q5) with the lowest (Q1) were 0.74 (95% CI = 0.42, 1.30) and 1.07 (95% CI = 0.51, 2.22), respectively. However, in multivariate analyses controlling diastolic blood pressure, exercise, alcohol, E1, and DHT:T ratio, we observed a strong trend for increasing risk across quintiles for E2 (Q5 vs. Q1 OR = 3.56, P trend = 0.009), and a weak inverse trend for E1 (Q5 vs Q1 OR = 0.51, P trend = 0.07). The excess risk associated with E2 was confined to men with relatively low androgen levels. Three nonhormonal factors previously suspected as risk factors were independently associated with surgical BPH in these data. The OR for a 1-mm Hg difference in diastolic blood pressure was 1.04 (95% CI = 1.01, 1.07). Alcohol use and infrequent exercise were inversely associated with risk of BPH surgery; however, risk estimates were not consistent across categories of exercise and alcohol frequency. Our results indicate that normal variation in circulating androgen levels does not influence development of BPH, but that variation in estrogen levels might be important.
37. Estrogen formation in human prostatic tissue from patients with and without benign prostatic hyperplasia. Stone NN, Fair WR, Fishman J Prostate 1986;9(4):311-8
Prostatic tissue removed at the time of cystoprostatectomy was separated into periurethral and peripheral zones. Homogenized tissue was incubated with [1,2,6,7(3)H] androstenedione in the presence or absence of an aromatase inhibitor, 4-hydroxyandrostenedione (4-OHAD) and a 5 alpha-reductase inhibitor 4-MA (N,N-diethyl-4-methyl-3-oxo-4-aza-5 alpha-androstane 17 beta-carboxamide). Estrogen formation was determined by reverse isotope dilution of [3H] estrone and [3H] estradiol and crystallization to constant specific activity. Control incubations were carried out in parallel utilizing heated prostatic tissue. Total estrogens produced in the periurethral zone in patients with benign prostatic hyperplasia (BPH) was 223 fmol/mg protein/hr (SE +/- 57) compared to 102 fmol (SE +/- 17) in patients without BPH. Estrogen formation in the peripheral zone was 175 fmol (SE +/- 69) and 105 fmol (SE +/- 26) in patients with and without BPH, respectively. The prostatic aromatase exhibits Michaelis-Menton kinetics with an apparent Km of 90 nM. 4-OHAD inhibited aromatization in the prostatic tissue by 57-93%. Aromatization was also strongly inhibited by 4-MA, indicating that 4-MA is a potent aromatase as well as a 5 alpha-reductase inhibitor in this tissue. These results suggest that aromatization of androgens to estrogens in the human prostate proceeds at a substantial rate and that local estrogen formation could preexist and be a factor in the etiology of BPH and prostatic cancer.
38. Expression of estrogen receptor in diseased human prostate assessed by non-radioactive in situ hybridization and immunohistochemistry. Ehara H; Koji T; Deguchi T; Yoshii A; Nakano M; Nakane PK; Kawada Y Department of Urology, Gifu University School of Medicine, Japan. Prostate 1995 Dec;27(6):304-13
To understand the role of estrogen in the pathogenesis of benign prostatic hyperplasia, expressions of estrogen receptor (ER) mRNA and ER protein by in situ hybridization and by immunohistochemistry, respectively, were investigated in human prostatic tissues. In non-malignant region, ER mRNA and ER protein were found in cytoplasm and nucleus, respectively, of stromal cells, but not in glandular epithelial and basal cells. In benign regions, ER mRNA/ER protein positive cells were found in fibromyoadenomatous and myoadenomatous hyperplasia, but not in adenomatous hyperplasia. A striking feature was periacinar arrangement of ER mRNA/ER protein positive stromal cells in all prostate carcinoma treated with androgen withdrawal. The ER mRNA/ER protein positive cells were immunohistochemically identified as fibroblasts, myoblasts, and smooth muscle cells. These results indicate that stromal cells are the primary target of estrogen in prostate, and that androgen withdrawal upregulates the expression of ER gene.
39. Roles of estrogen and SHBG in prostate physiology. Farnsworth WE Department of Urology, Northwestern University Medical School, Chicago, Illinois, USA. Prostate 1996 Jan;28(1):17-23
Heretofore, the function of estrogen in the prostate, other than as an antiandrogen, has been unclear. In this review of a growing fund of knowledge about both estrogen and the plasma protein, sex hormone-binding globulin (SHBG), or testosterone-estradiol binding globulin (TeBG), the hypothesis is proposed that estrogen, mediated by SHBG, participates with androgen in setting the pace of prostatic growth and function. It is suggested that the estrogen not only directs stromal proliferation and secretion, but also, through IGF-I, conditions the response of the epithelium to androgen.
40. [The role of tissue steroids in benign hyperplasia and prostate cancer]. [Article in German] Voigt KD, Bartsch W Universitatskrankenhaus Eppendorf, Abteilung fur klinische Chemie, Hamburg. Urologe [A] 1987 Nov;26(6):349-57
This paper presents a large body of data relating to benign prostatic hyperplasia, which have been derived from fundamental endocrinological research. For the urologist, the data open up interesting aspects of the pathomorphology of prostatic hyperplasia. The most interesting findings can be summed up as follows: 1. Testosterone is the circulating androgenic prohormone that mediates the intracellular message leading to androgen secretion, though by way of its metabolite dihydrotestosterone, which is really the active substance. 2. This metabolic conversion is catalyzed by 5 alpha-reductase, which is predominantly a stromal enzyme. 3. The estrogen metabolism in the stromal cells of the prostate may be associated with the abnormal growth of the prostate. 4. In the presence of benign prostatic hyperplasia dihydrotestosterone and 17 beta-estradiol accumulate in the nuclei of the stromal cells. 5. Adrenal androgens are also metabolized in the human prostate, yielding some substances with androgenic and some with estrogenic potency. 6. Changes in sex hormone binding globulins (SHBG) are found with age whether benign prostatic hyperplasia is present or not. It is therefore questionable whether it has any influence on the development of prostatic hyperplasia. 7. Although in some cases it is not yet possible to determine whether the findings presented in this paper have any causal significance, the data can be used as a rational basis for hormonal treatment of prostatic disease.
41. Estradiol causes the rapid accumulation of cAMP in human prostate. Nakhla AM; Khan MS; Romas NP; Rosner W Department of Medicine, St. Luke's/Roosevelt Hospital Center, New York, NY 10019. Proc Natl Acad Sci U S A 1994 Jun 7;91(12):5402-5
Androgens are widely acknowledged to be central to the pathogenesis of benign prostatic hypertrophy (BPH). However, BPH increases in prevalence as men age, at precisely the stage of life when plasma androgens are decreasing. The decrease in total plasma androgens is amplified by an age-related increase in plasma sex hormone-binding globulin (SHBG) that results in a relatively greater decrease in free androgens than in total androgens. In addition, estrogens have long been suspected to be important in BPH, but a direct effect on the human prostate has never been demonstrated. We present data that are consistent with a role for estradiol, and for a decrease in androgens and an increase in SHBG, in the pathogenesis of BPH. We show that estradiol, but not dihydrotestosterone, acts in concert with SHBG to produce an 8-fold increase in intracellular cAMP in human BPH tissue. This increase is not blocked by an antiestrogen and is not provoked by an estrogen (diethylstilbestrol) that does not bind to SHBG, thus excluding the classic estrogen receptor as being operative in these events. Conversely, dihydrotestosterone, which blocks the binding of estradiol to SHBG, completely negates the effect of estradiol. Finally, we demonstrate that the SHBG-steroid-responsive second-messenger system is primarily localized to the prostatic stromal cells and not to the prostatic epithelial cells. Thus, we have shown a cell-specific, powerful, nontranscriptional effect of estradiol on the human prostate.
42. The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranes. Hryb DJ, Khan MS, Romas NA, Rosner W Department of Medicine, St. Luke's/Roosevelt Hospital Center, New York, N.Y. 10019. Planta Med 1995 Feb;61(1):31-2
Extracts from the roots of the stinging nettle (Urtica dioica) are used in the treatment of benign prostatic hyperplasia. The mechanisms underlying this treatment have not been elucidated. We set out to determine whether specific extracts from U. dioica had the ability to modulate the binding of sex hormone-binding globulin to its receptor on human prostatic membranes. Four substances contained in U. dioica were examined: an aqueous extract; an alcoholic extract; U. dioica agglutinin, and stigmasta-4-en-3-one. Of these, only the aqueous extract was active. It inhibited the binding of 125I-SHBG to its receptor. The inhibition was dose related, starting at about 0.6 mg/ml and completely inhibited binding at 10 mg/ml.
43. Effects of stinging nettle root extracts and their steroidal components on the Na+,K(+)-ATPase of the benign prostatic hyperplasia. Hirano T, Homma M, Oka K Department of Clinical Pharmacology, Tokyo College of Pharmacy, Japan. Planta Med 1994 Feb;60(1):30-3
The effects of organic-solvent extracts of Urtica dioica (Urticaceae) on the Na+,K(+)-ATPase of the tissue of benign prostatic hyperplasia (BPH) were investigated. The membrane Na+,K(+)-ATPase fraction was prepared from a patient with BPH by a differential centrifugation of the tissue homogenate. The enzyme activity was inhibited by 10(-4)-10(-5) M of ouabain. The hexane extract, the ether extract, the ethyl acetate extract, and the butanol extract of the roots caused 27.6-81.5% inhibition of the enzyme activity at 0.1 mg/ml. In addition, a column extraction of stinging nettle roots using benzene as an eluent afforded efficient enzyme inhibiting activity. Steroidal components in stinging nettle roots, such as stigmast-4-en-3-one, stigmasterol, and campesterol inhibited the enzyme activity by 23.0-67.0% at concentrations ranging from 10(-3)-10(-6) M. These results suggest that some hydrophobic constituents such as steroids in the stinging nettle roots inhibited the membrane Na+,K(+)-ATPase activity of the prostate, which may subsequently suppress prostate-cell metabolism and growth.
44. The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse. Lichius JJ, Muth C Institut fur Pharmazeutische Biologie, Philipps-Universitat, Marburg, Germany. Planta Med 1997 Aug;63(4):307-10
Extracts of stinging nettle roots (Urtica dioica L. Urticaceae) are used in the treatment of benign prostatic hyperplasia (BPH). We established a BPH-model by directly implanting an urogenital sinus (UGS) into the ventral prostate gland of an adult mouse. Five differently prepared stinging nettle root extracts were tested in this model. The 20% methanolic extract was the most effective with a 51.4% inhibition of induced growth.
45. Severe sexual impairment produced by morbid obesity. Report of a case. Blum I; Marilus R; Barasch E; Sztern M; Bruhis S; Kaufman H Department of Medicine C, Rokach (Hadassah) Hospital, Tel-Aviv, Israel. Int J Obes (ENGLAND) 1988, 12 (3) p185-9
A 45-year-old man, was admitted for investigation of severe sexual impairment. During 20 years of marriage, he had had no normal sexual intercourse and the couple was childless. Physical examination disclosed a severely obese man (weight 300 kg, height 1.75 m), with a relatively small and invaginated penis and small (5 ml) soft testes. Laboratory examinations disclosed the following: low serum testosterone (1 ng/ml), with a reduced response to HCG (3.8 ng/ml). Sex hormone binding globulin was at the lower limit of normal (0.38 microgram/dl), serum free testosterone was low (0.98% of total testosterone) as well as non-SHBG bound testosterone (22% of total testosterone). Daily total urinary estrogen excretion was increased (107 micrograms), the plasma estrone (78 pg/ml) and estradiol (74 pg/ml) were elevated. The gonadotropins were normal and responded adequately to LRH. Plasma growth hormone was decreased, prolactin, T4 and adrenal steroids were normal and responded normally to stimuli and inhibitors. Chromosomal constitution was 46XY. Thus, in this man the marked obesity produced a significant increase in estrogens which subsequently induced a severe decrease in testosterone and its free counterpart in excessive impairment of sexual function.
46. The Testosterone Syndrome Shippen and Fryer 1998 M. Evans and Company New York, NY
No abstract.
47. Endocrine aspects of ageing in the male. Gooren LJ Department of Endocrinology, Hospital of the Vrije Universiteit, Amsterdam, The Netherlands. firstname.lastname@example.com Mol Cell Endocrinol 1998 Oct 25;145(1-2):153-9
There is a statistical decline of testosterone levels in ageing men, most manifest in free testosterone. While this fall is only moderate, ageing men show clinical signs of hypogonadism (loss of muscle mass/strength, reduction in bone mass and an increase in visceral fat). This might represent not only a fall but (also) an impairment of the biological action of androgens in target organs. The first small scale studies of androgen supplement administration in ageing men were not disappointing. Anticipated risks lie with the prostate and the cardiovascular system. The risks with regard to prostate disease are often over-rated. The question remains how the segment of the ageing male population possibly benefiting from androgen supplements, can be identified. For the treatment of postmenopausal women 'designer oestrogens' are being developed; similarly, designer androgens retaining beneficial anabolic effects with elimination of harmful effects on the prostate and cardiovascular system, could be devised.
48. [Sexual hormones in ageing males (author's transl)] Kley HK; Nieschlag E; Wiegelmann W; Kruskemper HL Aktuelle Gerontol (Germany, West) Feb 1976, 6 (2) p61-7
Alterations of sexual hormones in plasma of ageing males occur between the 50th and 60th year of life with individual variations: 1. Decreased values of testosterone in plasma and a poor response to gonadotrophins demonstrate a diminished synthesizing capacity of the testes in old men. 2. The decreased testosterone plasma values are followed by an increase in LH. The response of the anterior pituitary gland to LH-RH stimulation in old men is normal. 3. Under basal conditions estrone as well as estradiol plasma concentrations increase significantly with age because of increased conversion from androgens. 4. Parallel to estrogen plasma values an increased concentration of the sexual hormone binding globulin (SHBG) is found, resulting in a steep decrease of the free (= active) testosterone fraction. 5. Decreased testosterone, which is more strongly bound to SHBG and increased estrone and estradiol plasma values result in an androgen/estrogen imbalance in old men. (25 Refs.)
49. Direct effects of estrogens on the endocrine function of the mammalian testis. Moger WH Can J Physiol Pharmacol 1980 Sep;58(9):1011-22
This article reviews literature relevant to the view that estradiol (E2) synthesized in the testis acts locally to modify testosterone secretion. Despite a lack of convincing evidence from in vitro experiments, in vivo experiments with intact and hypophysectomized animals have demonstrated that estrogens can inhibit testosterone secretion by acting directly on the testis. Reduced testosterone production in estrogen-treated animals probably results from reduced 17 alpha-hydroxylase and (or) C17-C20 lyase activity. Estrogen-inhibited steroidogenesis may result from estrogen binding to high affinity--low capacity estrogen receptors. Besides being an estrogen target tissue, the testis produces E2; the cellular site of testicular E2 synthesis remains controversial. Recent studies indicate that E2 is synthesized primarily in the Sertoli cells of neonatal rats and in the Leydig cells of older rats. Follicle-stimulating hormone and human chorionic gonadotropin (hCG) increase testicular aromatase activity and E2 concentrations in neonatal and older rats, respectively. An increase in testicular E2 concentrations, following hCG administration, may be one mechanism by which testosterone synthesis becomes desensitized to subsequent hCG stimulation. However, whether gonadotropin-stimulated testicular E2 synthesis is part of a physiologically relevant "short" feedback loop that participates in the regulation of testosterone synthesis remains to be determined.
50. Direct inhibitory effect of estrogen on the human testis in vitro. Namiki M, Kitamura M, Nonomura N, Sugao H, Nakamura M, Okuyama A, Utsunomiya M, Itatani H, Matsumoto K, Sonoda T Department of Urology, Osaka University Medical School, Japan. Arch Androl 1988;20(2):131-5
The direct inhibitory effects of estrogens on human testicular functions were investigated with a testicular organ culture technique. 125I-labeled human chorionic gonadotropin (125I-hCG) bindings in testes cultured in media containing diethylstilbestrol diphosphate (DESDP) began to dose-relatedly decrease a day after the start of the culture, and this decrease remained relatively constant during the 5-day culture. On the other hand, testosterone produced by the cultured testes time-relatedly decreased during the 5-day culture. From the above results it may be concluded that the direct inhibitory effect of estrogens on human testicular androgen production consists of not only the loss of testicular hCG receptors but also of other mechanisms at a distal step from hCG receptor activation.
51. The acute effect of estrogens on testosterone production appears not to be mediated by testicular estrogen receptors Damber JE; Bergh A, Daehlin L, Ekholm C, Selstam G, Sodergard R Department of Physiology, University of Umea, 90187, Umea. Mol Cell Endocr 31 (1). 1983. 105-116.
Scatchard binding analysis was performed to measure the cytoplasmic estrogen receptor in the testis of rats. After treatment of rats with the antiestrogen tamoxifen no estrogen receptor binding was found in testicular low speed supernatant between 12 and 96 h after treatment. Such tamoxifen-treated rats were used to study the acute effect of estrogens on testosterone secretion, both in vivo and in vitro. Injection of estradiol benzoate (50 .mu.g, 24 h prior to experiment) resulted in a significant depression of basal and LH[lutropin]-stimulated plasma testosterone levels in control rats and this effect was unchanged in tamoxifen-pretreated rats. In vitro, estradiol-17.beta. also inhibited the LH-induced rise in testosterone secretion by isolated testicular interstitial cells. This inhibition was not affected if the rats had been pretreated with tamoxifen. The inhibitory effects of exogenous estrogens on testicular testosterone production are probably not mediated by the estrogen receptor.
52. The effect of testosterone aromatization on high-density lipoprotein cholesterol level and postheparin lipolytic activity. Zmuda JM; Fahrenbach MC; Younkin BT; Bausserman LL; Terry RB; Catlin DH; Thompson PD Department of Medicine, Miriam Hospital, Providence, RI. Metabolism (United States) Apr 1993, 42 (4) p446-50,
Stanozolol, an oral 17 alpha-alkylated androgen, increases hepatic triglyceride lipase activity (HTGLA) and decreases high-density lipoprotein cholesterol (HDL-C) levels, whereas intramuscular testosterone has comparatively little effect. In the present study, we tested the hypothesis that aromatization of androgen to estrogen blunts the lipid and lipase effects of exogenous testosterone. Fourteen male weightlifters received testosterone enanthate (200 mg/wk intramuscularly), the aromatase inhibitor testolactone (250 mg four times per day), or both drugs together in a randomized cross-over design. Serum testosterone level increased during all three drug treatments, whereas estradiol level increased only with testosterone alone (+47%, P < .05), demonstrating that testolactone effectively inhibited testosterone aromatization. Testosterone decreased HDL-C(-16%, P < .05), HDL2-C(-23%, NS), and apoprotein (apo) A-I (-12%, P < .05) levels, effects that were consistently but not significantly greater with simultaneous testosterone and testolactone administration (HDL-C, -20%; HDL2-C, -30%; apo A-I, -15%; P < .05 for all). In contrast, both testosterone regimens decreased HDL3-C levels by 13% (P < .05 for both). HTGLA increased 21% during testosterone treatment and 38% during combined testosterone and testolactone treatment (P < .01 for both). Lipoprotein lipase activity (LPLA) increased only during combined testosterone and testolactone treatment (+31%, P < .01), suggesting that estrogen production may counteract the effects of testosterone on LPLA. Testolactone alone had little effect on any lipid, lipoprotein, apoprotein, or lipase concentration.(ABSTRACT TRUNCATED AT 250 WORDS)
53. Effects of estradiol administration in vivo on testosterone production in two populations of rat Leydig cells Keel B.A.; Abney T.O. Dep. Endocrinol., Med. Coll. Georgia, Augusta, GA 30912 United States Biochemical and Biophysical Research Communications (United States) 1982, 107/4 (1340-1348)
The effects of in vivo administration of estradiol on isolated rat testicular Leydig cells were investigated. Adult intact rats were injected s.c. with 50 mug/100 g B.W. of 17beta-estradiol or vehicle twice daily for 2 days. Twelve hours after the last injection, collagenase dispersed interstitial cells were obtained and Leydig cells were subsequently isolated on metrizamide gradients. Two distinct peaks of specific sup 1sup 2sup 5I-hCG binding corresponding to population I and II Leydig cells were observed. The hCG binding profile was unaltered as a result of estradiol treatment. Although twice as much testosterone was produced in population II, the responsiveness of the two populations to hCG or dbcAMP in vitro was identical (11- to 13-fold increase). Estradiol administration in vivo resulted in a 33-48% decrease in basal and stimulated testosterone production in both populations. These data indicate for the first time that both population I and II Leydig cells are sensitive to the direct inhibitory effects of estrogens on testosterone production. This inhibitory effect was not associated with an alternation in hCG binding capacity in either population. Therefore, we conclude that no functional difference exists between the two populations of Leydig cells with respect to the action of estrogens.
54. Tetrahydroisoquinoline alkaloids mimic direct but not receptor-mediated inhibitory effects of estrogens and phytoestrogens on testicular endocrine function. Possible significance for Leydig cell insufficiency in alcohol addiction. Stammel W, Thomas H, Staib W, Kuhn-Velten WN Abteilung Physiologische Chemie, Universitat Ulm, F.R. Germany. Life Sci 1991;49(18):1319-29
Possible effects of various tetrahydroisoquinolines (TIQs) on rat testicular endocrine function were tested in vitro in order to prove whether these compounds, some of which have been claimed to accumulate in alcoholics, may be mediators of the development of Leydig cell insufficiency, a well-known side-effect of ethanol ingestion. TIQ effects on different levels of regulation of testis function were compared in vitro with estrogen effects, since both classes of compounds have structural similarities. Gonadotropin-stimulated testosterone production by testicular Leydig cells was inhibited by tetrahydropapaveroline and isosalsoline, the IC50 values (30 microM) being comparable to those of estradiol (3 microM), 2-hydroxyestradiol (10 microM), and the phytoestrogens, coumestrol (15 microM) and genistein (7 microM); salsolinol (85 microM) and salsoline (240 microM) were less effective, and salsolidine was ineffective. None of these TIQs interacted significantly with testicular estrogen receptor as analyzed by estradiol displacement. However, tetrahydropapaveroline, isosalsoline and salsolinol competitively inhibited (Ki 130-150 microM) substrate binding to cytochrome P450XVII, one key enzyme of androgen biosynthesis, with similar efficiency as the estrogens did (Ki 50-110 microM); salsoline and salsolidine were again much less effective. Since the efficient TIQ concentrations in this system are identical with those reported to generate central-nervous effects, it is concluded that certain TIQs may amplify peripheral inhibitory effects of ethanol on testicular endocrine function by their interaction with at least one enzyme of the androgen biosynthetic pathway.
55. Levels of sex hormone-binding globulin and corticosteroid-binding globulin mRNAs in corpus luteum of human subjects: correlation with serum steroid hormone levels. Misao R, Nakanishi Y, Fujimoto J, Iwagaki S, Tamaya T Department of Obstetrics and Gynecology, Gifu University School of Medicine, Japan. [Medline record in process] Gynecol Endocrinol 1999 Apr;13(2):82-8
To understand regulation of the function of human ovarian corpus luteum by sex steroid-binding proteins, the levels of luteal intracellular sex hormone-binding globulin (SHBG) and corticosteroid-binding globulin (CBG) mRNAs and serum steroid hormones were simultaneously determined. The expression of SHBG and CBG mRNAs was detected in all samples analyzed. SHBG mRNA level was positively correlated with serum estradiol-17 beta level (p < 0.05), but not with serum progesterone level. There was a positive correlation between SHBG mRNA level and serum estradiol-17 beta/progesterone ratio (p < 0.01). On the other hand, CBG mRNA level was positively correlated with serum estradiol-17 beta and progesterone level (p < 0.01 and p < 0.01, respectively). There was no correlation between CBG mRNA level and serum estradiol-17 beta/progesterone ratio. SHBG and CBG mRNA levels were not correlated with the levels of serum testosterone, free testosterone or cortisol. These findings suggest that the synthesis of luteal SHBG and CBG is complexly regulated by estrogen and progesterone, and that SHBG and CBG interact with estrogen and progesterone, respectively, for luteal steroidal activity.
56. Effects of ethinyloestradiol on plasma levels of pituitary gonadotrophins, testicular steroids and sex hormone binding globulin in normal men. Van Look PF, Frolich M Clin Endocrinol (Oxf) 1981 Mar;14(3):237-43
Daily measurements of plasma FSH, LH, prolactin, testosterone, 17 beta-oestradiol and sex hormone binding globulin (SHBG) activity were made in eight healthy, normal men during treatment with oral ethinyloestradiol (EE2) in a dose of 30 micrograms/day for 5 days following a 5-day control period. No significant changes in plasma levels of FSH and prolactin during oestrogen treatment occurred. In contrast, plasma concentrations of both LH and testosterone showed a biphasic pattern. Following an initial suppression during the first 3 days of oestrogen treatment both LH and testosterone increased again to baseline values despite continuation of oestrogen administration. The secondary rise of both hormones was associated with (and probably resulted from) a nearly 100% increase in the plasma concentration of SHBG binding activity, and hence reduction of free testosterone index (FTI). Unlike testosterone, plasma 17 beta-oestradiol during EE2 administration did not show a biphasic pattern, but a progressive decline that was positively correlated with the fall in FTI. The rapidity of onset and magnitude of the observed rise in SHBG levels emphasizes the need for measurement of this binding protein (or the free testosterone fraction) in studies on feedback regulation of gonadotrophins employing exogenous EE2 in human males. The observed increase of SHBG to supraphysiological values suggests that currently employed EE2 doses in such studies may be less 'physiologic' than is often assumed.
57. Changes in testosterone muscle receptors: effects of an androgen treatment on physically trained rats. Bricout VA; Germain PS; Serrurier BD; Guezennec CY IMASSA-CERMA, Departement de Physiologie Systemique, Bretigny sur Orge, France. Cell Mol Biol (Noisy-le-grand) 1994 May;40(3):291-4
From results obtained in physiological investigations carried out on various tissues sensitive to androgens, it seems that the hormonal receptivity can reflect changes in the endocrine status and specific response of a tissue. The purpose of the present investigation was to test whether an androgen treatment could modify the receptivity to testosterone of the skeletal muscle and myocardium of endurance trained rats. The experiment extended over 8 weeks, and animals received injections of delayed testosterone heptylate every seven days. The myocardium and two skeletal muscles with opposed functions and typology were examined: the extensorum digitorum longus (EDL), and the soleus (SOL). Results obtained using techniques based upon the radio-competition principles provided information on the testosterone-receptor binding. The binding curves were plotted up to the saturating concentration of tritiated mibolerone, a synthetic androgen specific of androgen receptors. The quantity of receptors, calculated at the specific saturation plateau is expressed in fmol/mg protein. Results show that contractile muscular activity always increased the quantity of receptors whereas the steroid treatment decreased it. Thus for EDL and SOL of control trained rats the quantity of receptors was 0.78 and 0.82 fmol/mg protein, respectively, compared to 0.23 and 0.43 fmol/mg protein for sedentary testosterone-treated rats. The same "contractile activity" effect was observed on the myocardium but enhanced with values of 1.63 fmol/mg protein for control trained rats versus 0.30 fmol/mg protein for sedentary testosterone-treated rats. The receptivity to testosterone of the skeletal muscle and myocardium changes under the effect of an androgen treatment.
58. Steroid hormones and neurotrophism: relationship to nerve injury. Jones KJ Department of Biological Chemistry and Structure, University of Health Sciences, Chicago Medical School, Illinois 60064. Metab Brain Dis (United States) Mar 1988, 3 (1) p1-18
Current data on the neurotrophic effects of steroid hormones suggest that, in brain and spinal cord regions containing receptor systems, steroids act at the level of RNA and protein synthesis to effect metabolic changes associated with nerve-cell survival, elaboration/maintenance of dendritic and axonal processes, synaptogenesis, and neurotransmission. While many of these effects appear to be associated with the neuroanatomical systems involved in the endocrine and behavioral aspects of reproduction, evidence does exist for similar neurotrophic effects outside the reproductive sphere. Both estrogens and androgens appear to exert this stimulatory, growthlike effect on target neurons. The effects of progesterone are not discussed in this review because relatively little information is available regarding the independent effects of progesterone on the brain . We have just completed a study (Jones et al., 1987b) which suggests that progesterone may act independently in the brain to affect protein synthesis. A number of conclusions concerning the mechanism of steroid action in producing trophic effects on neurons can be drawn. First, the time course of hormone action is similar to that found in nonneural target tissue, such as the uterus. Second, steroid hormones act on neurons through receptor-mediated genomic activation. Third, this effect on the genome appears to be at the level of both transcription and translation. Fourth, there is brain -region specificity in the gene products resulting from steroid hormone administration. Finally, short-term exposure to estrogens or androgens generally results in an anabolic response within target neurons. The brain and spinal cord, injured either by disease or by experimentally induced trauma , is responsive in a reparative manner to exogenous and/or endogenous gonadal steroid hormones. The mechanism underlying this therapeutic role of steroids on damaged neurons is not known but has been postulated to involve direct action of steroid hormones or target neurons. It has been hypothesized that two diseases, Alzheimer's and ALS, may be related to steroid hormone/receptor deficiencies. In this regard, Appel (1981) has suggested that putative "neurotrophic hormones" acting at the synapse may be critical in maintaining the neural networks affected in ALS, Alzheimer's disease, and parkinsonism. Extending that hypothesis to include direct action of such putative hormones within the cell body and at the level of the genome, the evidence presented in this discussion would argue that possible candidates could be gonadal steroids.
59. Androgen deficiency and aging in men. Swerdloff RS, Wang C Department of Medicine, University of California, Los Angeles, School of Medicine. West J Med 1993 Nov;159(5):579-85
Androgen levels decrease with age in men. Androgen deficiency in men older than 65 years leads to asthenia, a decrease in muscle mass, osteoporosis, and a decrease in sexual activity. Androgen deficiency has been reported to cause changes in mood and cognitive function. The combination of these factors results in impaired quality of life in older men. Androgen replacement therapy in hypogonadal men increases bone and muscle mass, enhances muscle and cardiovascular function, and improves sexual function and general well-being; whether elderly men experience benefits of androgen replacement is not known. These benefits have to be weighed against the possible adverse effects of prostate and cardiovascular diseases. Careful long-term studies are needed to assess the risk-to-reward ratios of androgen or other hormone replacement therapy before treatment strategies similar to estrogen therapy for postmenopausal women are implemented.
60. Androgens and aging in men. Swerdloff RS, Wang C Division of Endocrinology, Harbor-UCLA Medical Center, Torrance 90509. Exp Gerontol 1993 Jul-Oct;28(4-5):435-46
Androgen levels decrease with aging in men. Androgen deficiency in elderly men may lead to asthenia, decrease in muscle mass, osteoporosis, decrease in sexual activity, and, in some cases, changes in mood and cognitive function. Combination of these factors may result in impaired quality of life in the elderly male. Androgen replacement therapy may increase bone and muscle mass, enhance muscle and cardiovascular function, and improve sexual function and general well-being. These potential benefits of androgens have to be weighed against the possible adverse effects on prostate and cardiovascular diseases. Careful long-term studies will be required to assess the risk-to-reward ratios of androgen or other hormone replacement therapy before the development of treatment strategies similar to estrogen and progestagen substitution therapy for the postmenopausal female.
Click to go to the Life Extension Foundation Web Site


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— The Indianapolis Museum of Art recently announced that Brooklyn-based artist Spencer Finch will create a new installation as part of the IMA's Efroymson Family Entrance Pavilion series.
Finch's new installation, "Following Nature," will be composed of an array of nearly 200 panels of glass suspended from the pavilion's ceiling, as a reinterpretation of Claude Monet's iconic water garden in Giverny, France. "Following Nature" will be on display from Feb. 1 to Aug. 25.
Inspired by a recent visit to Giverny, Finch has looked to the representation of water as a shaping influence for "Following Nature," in particular Monet's use of the water garden as a kind of laboratory for optical effects. Monet has served as an inspiration for Finch for more than 20 years, and the IMA's installation will be his second exploration of the garden in Giverny, following the 2012 exhibition of his work "Painting Air" at the Museum of Art Rhode Island School of Design.
Unlike Monet's representations of the garden through the two-dimensional medium of paint on canvas, Finch's all-encompassing installation radically reinterprets this well-known site. The work will comprise numerous glass panels of varying reflectivity, surrounded by a multi-hued field of translucent vinyl applied to the pavilion's existing windows. Finch sourced the colors for the window vinyl from his photographs of the gardens, color samples taken on site, and pigment colors used by Monet.
The installation's title is drawn from a letter written by Monet to his friend Gustave Geffroy in 1889, in which Monet states, "In light of changes (in the weather) I am following nature without being able to grasp her, and then there is the river that shrinks, swells again, green one day, then yellow, sometimes almost dry, and which tomorrow will be a torrent, after the terrible rain that is falling at the moment."
Correspondingly, Finch's "Following Nature" will embody the garden as an evolving, spatial, and optical experience rather than as a single moment in time. As light shifts across the work's glass panels and the pavilion's tinted windows, viewers will be immersed in a sensory environment of changing kaleidoscopic reflections. The installation's use of the pavilion's windows will also unite Finch's impression of the Giverny gardens with the IMA's own landscape and will obscure the division between inside and outside.
"Only Spencer Finch - one of contemporary art's foremost creative minds - could transport a viewer from Indianapolis in February to Monet's garden in Giverny at the peak of summer," said Sarah Urist Green, curator of contemporary art.
"Following Nature" is part of the Efroymson Family Entrance Pavilion series launched in February 2007 and made possible by a $2.5 million grant from the Indianapolis-based Efroymson Family Fund. The works are installed on a rotating basis with a new commission from a different artist approximately every six months. Artists who have previously exhibited in the space include Alyson Shotz, William Lamson, Orly Genger, Julianne Swartz, and Tony Feher, among others.
A reception and artist talk in celebration of the opening of Finch's installation will be Jan. 31. The reception is 5 p.m. in The Toby lobby and the talk will begin at 6 p.m. in The Toby. The IMA is at 4000 Michigan Road. For more information, call 923-1331 or visit the website at www.imamuseum.org.


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There are many pre-existing medical conditions that can affect pregnancy or be affected by pregnancy that require the clinical care by a physician or other healthcare professional. Listed in the directory below are some, for which we have provided a brief overview.
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Hall's River House in Crystal River
- bedrooms 2
- baths 2
- sleeps 7
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- type House
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rates (USD)
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vacation rental description
This is a 2 bedroom, 2 bath home on the water in Crystal River.
It is about 1.5 hours from both the Orlando attractions and the
Tampa/St. Pete beaches and attractions.
The house comes with 2 two person kayaks. The Halls River is very
pristine. You can paddle for three miles and connect with the
Homosassa River. Most of the surrounding land is bird sanctuary. The
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great place to fish or just plain relax by the fire pit.
Everything you need is here. All you need to bring is your personal
belongings and food if you want to cook.
house rental amenities
BBQ grill, microwave, coffeepot, full kitchen utensils and linens,
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outdoor fireplace.
activities and attractions in Crystal River Gulf Coast Central
Local to world class golf, manatee tours, SCUBA diving and training,
kayaking, bird
watching, Horseback riding, etc.
vacation rental rates
During the wintertime peak period from Nov 15 through March 31 the
rate is $175.00 per night with a two night minimum for the first 2
adults and 2 children. There is a $10 per person fee after that and $20 cleaning fee.
The summertime rate from April 1st to Nov 14th is $150.00 per


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January 27–February 3
The poet Rachel vs. Sylvia Plath: The morose, heartrending existentialism of perfectionist women disappointed with life.
February 10
Fine arts: Israeli meagerness of matter vs. pop art, postmodernism, and colorful hedonism.
February 24–March 2
American Idol vs. "Kochav Nolad": Newly born stars as a threat to the old cultural regime and as common denominators of cultural classes.
March 9–March 16
Late Summer Blues vs. Hair: The youth protest against war that gave birth to flower children, hippies, and the Summer of Love.
March 23–March 30
How have the greatest athletes and sports events reflected and influenced the social, political, and cultural turmoil of their times?
April 13–May 4: Assembly schedule
Ofra Haza vs. Marilyn Monroe: The controversial, mysterious death of a goddess.
April 20: Passover (no Sunday classes)
May 11
Fashion police: Fads and fashions reach millions, shape cultural conceptions, and even overthrow governments and change the fate of war.
May 18: Graduation and last day of classes
How celebrities and tabloids contribute to social polarity. (other: Coca-Cola, jeans and McDonalds; corporate culture took over socialist values).


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Approximate Travel Time By Bus: 8 minutes
Approximate Travel Time By Car: 5 minutes
Days/Hours of Operation: Monday-Thursday 4:00-6:00pm for all programs
Orientation: TBD
Description of Agency: Notre Dame Middle School (NDMS) is a Catholic school for young women sponsored by the School Sisters of Notre Dame. Following in the Christian tradition, Notre Dame fosters respect, responsibility, and sharing of personal talents, and prepares students for admittance to a college preparatory high school. In a bi-literate (English an Spanish) setting, with emphasis on leadership skills, critical thinking, and social justice, young women are empowered to make positive contributions to society.
***New OPPORTUNITY: Primary School After-School Care Program
Description of Agency: NDMS has recently opened a Primary School, serving students ages K5 and up/ The After-School program is seeking one volunteer each afternoon to work one-on-one with a K5 students requiring extra supervision.
Days/Hours of Operation: Monday-Friday 3:00-5:45pm
Student Role: Students will have the opportunity to form a strong relationship with a young student and witness child development in the surrounding environment.
Commitment: 2-3 hours per week, every week for the entire semester, plus orientation. Service Learners are also required to attend a one-time, 3 hour class entitled "Safeguarding All of God's Family," an initial training for Safe Environment Education as mandated by the Archdiocese (not included in Service Learning hours).
For more information, see the Notre Dame Middle School Website.


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Hotels in Bahrain (all), Bahrain - your base to discover the city.
Hotels near Manama in Bahrain (all), Bahrain – Hotels.com offers the best selection of hotels near Manama and delivers many last minute hotel deals not found anywhere else online. Our hotel reviews, provided by thousands of guests, give you an unbiased view of what to expect when you arrive at your hotel. Use this page to search for discounted hotels with great rooms available near Manama in Bahrain (all).


text: South Hagerstown vs. Gov. Thomas Johnson Football 9/21 09/21/2012 03:57 PM 09/22/2012 12:09 AM South Hagerstown looks to stay undefeated against perennial powerhouse, Thomas Johnson. Game Highlights from 9/21South Hagerstown 21Thomas Johnson 14FINAL Copyright 2013 Nexstar Broadcasting, Inc. All rights reserved. Page: [[$index + 1]] governor thomas johnson high school high school/college sports local sports other local sports south hagerstown high school sports sports connection top stories


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Read more about how Think Through Math's instructional solution works in a variety of settings and implementation scenarios.
Diocese Wheeling-Charleston: Premium Education = Premium Math Supplementation
The Diocese of Wheeling-Charleston has always taken education seriously. In fact, their desire to provide each of their students with a premium-quality educational career has long been one of the touchstones of their one-size-does-not-fit-all educational philosophy. And like any educational institute concerned with delivering math instruction that rouses the potential of each child, the Diocese of Wheeling-Charleston administrators continuously challenge themselves to identify new ways to further math achievement.
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Students Accelerate to Grade Level and are Lauded by Louisiana Superintendent of Education
Responding to a state mandate, Ascension Parish took action to identify students 15 years of age or older who were at least two years behind in math achievement. In January, 2013, State Superintendent of Education John White told Ascension Parish educators their achievements serve as a model for other districts in the state.
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Intensive Summer Program Produces 78% of Students Passing the Georgia CRCT
A number of 8th grade students at Malcom Bridge Middle School failed the Criterion-Referenced Competency Test (CRCT) and were at-risk for of not being permitted to move to 9th grade. After a one-month intensive summer school program using Think Through Math this group went from 0% to 78% passing.
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Nine-Week Implementation to Improve Test Scores Results in 38% Increase in Proficiency
In late January 2011, students in 59 classrooms began working with Think Through Math continually through April. Teachers encouraged students to go online at home, and to also attend the learning lab before the regular school day, taking advantage of the program's Web-based anytime/anywhere access.
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Gains on WESTEST 2011: Beckley-Stratton Middle School Sees Gains across the Board
Beckley-Stratton Middle School knew its students had the capacity to succeed. At the end of the 2011 school year, 64% of students in the Think Through Math program achieved a significant increase in Quantile gains. Of this group, 41% achieved gains of 10% or more.
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Dedication and Fidelity Result in Gains on the PSSA
Students who used Think Through Math scored high on the Pennsylvania System of School Assessment (PSSA). Through a combination of personalized pathways targeting grade-level skills and concepts, students learned to better understand and love math. Their progress through the program predicted the success they achieved on the PSSA.
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81% of At-Risk Students Pass 8th-Grade TAKS after Intensive Implementation
Hogg Middle School identified a group of students at risk of not passing the 8th-grade TAKS. After implementing an intensive, secondary math class using Think Through Math, 81% of these at-risk students passed the TAKS on the first administration.
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Channelview ISD Finds a Pathway to Algebra Success with Think Through Math
In the 2010–11 school year, leaders at Channelview ISD implemented Think Through Math for all students at the Kolarik Ninth Grade Center, regardless of testing level. The strategy paid off with end-of-year standardized tests indicating 90% of students proficient in Algebra.
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Flour Bluff ISD Sees Solid Gains in Math
Like many districts across Texas, Flour Bluff Independent School District is focused on getting ready for STAAR, the highly-anticipated rigorous 2012 assessment. One of their most effective tools is Think Through Math. At the end of the 2011 school year, 59% had improved performance on TAKS, thanks in part to Think Through Math's unique blend of rigorous content and unprecedented motivation.
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