text:
Eagles Swimming Away with CCSA Championship
ATHENS, Ga. – At the end of day two, the Florida Gulf Coast women continue to lead in the championship with a score of 568 and Davidson is in second with 414 points. Georgia Southern is locked in third with 320 points at the conclusion of day two at the Gabrielsen Natatorium on the campus of the University of Georgia.
Day one finals of the CCSA Championship started off with the the Florida Gulf Coast team of Viktoria Hyddmark, Vicky Cadge, Margie Chamberlin and Isabela Mills Pinto earned the win in the 200 medley relay, finishing the race in a time of 1:44.06, which is a new League best. Gardner-Webb's relay team (Sarah Steadman, Stepheni Stadnik, Rachel Warkentin and Corey Hughey) finished second with a time of 1:44.34, notching second in the League and Georgia Southern (Lindsay Goodman, Ashley White, Kristen Haudenschild and Courtney Martz) swam in for third at 1:45.00, rounding out the top three in the Conference.
In the 400-yard IM, Florida Gulf Coast captured the gold with Rosy Murray finishing first (4:18.73), her second award of the week and earning the top spot in the Conference. Georgia Southern's Lauren Parr came in second (4:25.75) and touching the wall third was Davidson's Anna Stringfield, who clocked in at 4:25.88.
Davidson's Emily Castle swam a Conference best time in the 100-yard butterfly with a time of 54.62 to earn the win and her second medal thus far. Finishing second was Florida Gulf Coast's Margie Chamberlin, who clocked in at 55.23 and coming in third was Davidson's Courtney Sanders, who touched the wall at 55.60.
North Florida's Lyn Ann Nelson, who earned a Division I NCAA-B cut time and set the Conference record, grabbed gold in the 200-yard freestyle with a time of 1:47.52. This is her second medal this week. Florida Gulf Coast's Leah Daniel earned her second medal in the meet, touching the wall in 1:48.73 for the silver and second-place CCSA time, and Davidson's Lindsey Martin rounded out the top three (1:50.15) for her second medal this week.
In the women's 100-yard breaststroke each of the top finishers rounded out top the top three in the Conference, with Florida Gulf Coast's Vicky Cadge (1:03.60) earning the gold for the second time this week and teammate Catrina Silveira taking the silver. Finishing third in a time of 1:05.02 was Gardner-Webb's Stepheni Stadnik.
Gardner-Webb's Corey Hughey finished in first-place in the 100-yard backstroke for her second medal of the week, setting a CCSA top time of 50.40, and capturing an NCAA Division I B cut time while Florida Gulf Coast's Viktoria Hyddmark earned second (55.79) and Gardner-Webb's Sarah Steadman grabbed third (57.04). Hyddmark and Steadman round out the CCSA top times with their finishes.
In the 800-yard freestyle relay, Florida Gulf Coast (Rosy Murray, Rachael Rein, Margrete Ulvestad and Leah Daneil) earned the first-place finish with a time of 7:21.26 for first-place in the League. Davidson (Courtney Sanders, Caitlin Sheetz, Casey VanTassell and Anna Stringfield) came in second, clocking in at 7:31.64 and Georgia Southern (Caroline Bevillard, Lauren Parr, Jordyn Pasley and Ali Campbell) completed the race third with a time of 7:36.51.
The CCSA Championships will resume tomorrow morning at 10:00am.
|Copyright ©2014 FGCU Athletics. All Rights Reserved.


text:
Expired Property Listing
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Sunset Cove #16 in Ocean City
- bedrooms 2
- baths 2
- sleeps 6
- pool no
- hot tub no
- pets allowed no
- type Townhome
- community
rates (USD)
/ night
$ 600 - $ 1,450 / week
$ 2,500 - $ 6,500 / month
vacation rental description
This beautiful, just updated Townhome is on the Bayside located on the Canal at 94th Street. Back from the hustle and bustle of Ocean City yet just a few blocks off the beach and within walking distance of all of the resort's features. Easy access to swimming, surfing, golf, tennis and even Deep Sea Fishing! Great complex of two story townhouses located on open bay with beautiful views of the bay. Located off of 94th. Street near the end of Rusty Anchor Road, in a quiet bayside residential atmosphere.
2 Tennis Courts.
First floor features newly furnished den, 32" HDTV, full kitchen, laundry, full bath, lovely eat-in dining area and private porch AND INTERNET ACCESS!
2nd floor MBR features a queen sized bed with tv, adjacent full bath, and private balcony overlooking canal. 2nd large BR has a twin with a 2nd twin hidden beneath. Plenty of room to set up both supplied rollaway beds!
Mini-Weeks Welcome! Start or end on Saturday, 3-night minimum in June, July & August. Exceptions in some circumstances.
Weekly Bookings: Saturday to Saturday preferred in peak season.
townhome rental amenities
Free Internet
Cable HDTV
Private Porch off of Den
Private Balcony Overlooking Canal off of MBR
activities and attractions in Ocean City Maryland
Ocean and Beach
Thousands of Restaurants
vacation rental rates
Rates vary depending on season. Does not include cleaning or admin fees. Discounts offered for multiple night stays.

subset: commoncrawl


text:
Expired Property Listing
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West Shores of Cayuga Lake in Cayuga Lake
- bedrooms 3
- baths 1½
- sleeps 8
- pool no
- hot tub no
- pets allowed yes
- type House
- community Green Lane Shores
rates (USD)
/ week
vacation rental description
This beautiful West shore lake home is the perfect place to spend
your summer vacation. West side
living offers early sunrises and cooler evenings. The house is
located 14mi North of Ithaca (7mi
North of Taughannock Falls State Park). With 3 bedrooms (1 Qn, 1
full, 2 twin and a pull out couch) parties of 8 can all
sleep comfortably. The main living area, upstairs, is level to the
private parking lot and offers a
wraparound deck with water views, grill and picnic table, 2
bedrooms, full bath, fully equipped
kitchen, dining rm and sitting area. The lower living area offers
the 3rd bedroom and half bath
along with a second sitting area and lower level deck.
Dogs are welcome under conditions of up-to-date shots and leashed at all times outside house. Dogs must be registered at time of contract signing - additional dogs not registered will be asked to leave premises.
Due to the nature of the summer residence and association, please
note that we DO NOT allow large
parties (wedding receptions, graduations, reunions, etc). Please
feel free to contact us if you have
any questions.
house rental amenities
Sleeps 8 (1 Qn, 1 full, 2 twin and a pull out couch)
1.5 baths
Fully equipped kitchen (microwave, coffee maker)
Propane grill
Electric boat hoist
Linens & towels provided
28 total stairs in 3 levels to water
Private parking
You are responsible for the cleaning and garbage removal prior to leaving. If you would like for us to take care of your garbage we ask for $10/bag being removed.
activities and attractions in Cayuga Lake Finger Lakes
Several State Parks near by
Ice Cream Shops
Hiking trails
Cornell and Ithaca College w/in 14 miles
Dinner Cruises
Antique Shops
Farmer's Markets
Hanger Theater
Local Restaurants
Golf Courses (Ithaca & Trumansburg)
vacation rental rates
$1200 per week in June, September and October or $175 per night.
$1400 per week in July and August
Weekly rentals are from Sun (12pm) - Sun (10am)
Security deposit = 1/2 weekly rate (refundable)
Best way to contact us is by email.


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Most leagues have drafted, but there's still time to get into or create new leagues for those who haven't ventured over into the pastures of Yahoo! Fantasy.
Another call to arms for the ultimate fantasy: playing make-believe football with your BRB brothers and sisters.
Stampede Blue has 12 blog-sponsored Fantasy Football leagues this season, and Yahoo! gives us a great platform to run the leagues smoothly and easily.
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It's awesome. J.J. Watt is going to take the country by storm.
Let's take a peek at Fantasy Football for 2013
Continue to improve your team no matter what your record is, plenty of 7-6 teams that can win in the fantasy playoffs
NFL Fantasy Football - Who Do You Start at QB in Week #2? Are RGIII and Andrew Luck smart starts this week?
Preview of Week 2 of Fantasy Football.
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The Immortals Of Meluha is a thrilling story about a warrior named Shiva, who is given the responsibility to protect the empire of Meluha from dangerous intruders. This mythological novel is fast-paced, and focuses on duty, love, principles and more.
Summary Of The Book
The land of Meluha is an empire created by Lord Rama, and it is ruled by the Suryavanshis. This empire is powerful and proud, however, the Saraswati river that is their source of water is slowing drying up. On top of that, the empire is at war with the Chandravanshis who have allied with The Nagas, a group of sinister and deformed human beings who have extraordinary martial art skills.
The Immortals Of Meluha, published in 2010, is the first story of the trilogy. Daksha, the king of the Suryavanshis, realizes that his empire needs help. He invites a tribe from Tibet to help him fight off the enemies. The Tibetan Guna tribe is lead by Shiva, who is a fearless soldier, and the only one who does not fall ill on arriving at Meluha. To everyone's surprise, Shiva's throat turns blue.
The locals believe that this warrior is their fabled saviour Lord Shiva, also known as Neelkanth. Shiva goes to Devagiri to meet Daksha and his daughter Princess Sati. There, he learns about the dangerous wars and terror attacks that the Chandravanshis have carried out on the Meluhans.
The brave warrior gets enraged, and declares a full war on the enemy. Readers will find this mythological fantasy to be gripping and exciting. Questions about Shiva's duty, destiny, and karma arise throughout the book. The author has written a book that is adventurous, mystifying, and captivating, but at the same time he also has thrown light onto the subjects of what is evil, and who is truly a hero.
This page-turner is a treat for readers who enjoy history, fantasy, and adventure. The Immortals Of Meluha received good reviews from leading newspapers, and was a bestseller within its first week of release.
About Amish Tripathi
Amish Tripathi, born in 1974, is an Indian author. The second book of the series, The Secret of the Nagas, was published in 2011. The third and the last, The Oath of the Vayuputras, was released in 2013. The author's books have become the fastest selling book series in the history of Indian publishing. A total of 1.7 million copies have been sold, with a gross retail sale of Rs. 40 crores.
Tripathi's books revolve around religious and mythological topics, as he is a devotee of Lord Shiva. Tripathi graduated from the Indian Institute of Management, Calcutta, and worked in the financial sector for fourteen years in companies such as IDBI Federal Life Insurance, Standard Chartered, and DBS Bank. In 2012, he was ranked at position 85 of Forbes India's Celebrity 100 list.
|Book Details
|Publication Year
|Number of Pages
|412 Pages
|Nebula Awards
|Award Year
|0.28 inch
|0.04 inch
|227 g
There are few authors in India who write exceptionally well. Amish is one of those. I am a vivid reader and read almost all the books that come my way. This stands fifth.
1. Corporate Chanakya
2. That's the way we met - Sudeep Nagarkar
3. How I braved Any Aunty - Varun Aggarwal
4. The Backbenchers - Siddharth Oberoi
5. The immortals of Melhua- Amish Tripathi
One of my friend recommended this book and while reading I was so lost in it that I didn't realized I was on the last page. The ending of the book leaves you with curiosity to quickly jump to the next part. Same with the 2nd part "The Secret of Nagas"... Now I can't wait to get my hands on the last piece of the triology. The books is so brilliantly written that it truly deserves the title "Master Piece"
This book is a sure shot "BUY"
Amish has done a well work on Indian Mythology. One should read this book if he\she is interested in Ancient History of India. He has done some great research on Shiva and presented here... Like "HAR HAR MAHADEV" means every one is mahadev... I read it on the go... hope you find this review helpful...
Amazing Book to read , while reading it takes us with its flow , feels like its a movie. Excellenty written . This was my first book from flipkart and the delivery was quick.
I think a TV SERIES on this Book and its sequel The Secret Of The Nagas will be a great hit.
I borrowed and read this book from my friend who bought this from flipkart.
Actually I am a follower (I believe) of Lord Shiva and not the man Shiva (The fiction Character Mentioned Here).
Some Twisted Facts.
1.How come Lord Ganesh is Nor Lord Shivas son (In the story he is the son of sati's first husband).
2.Lord Ram Married Sita by breaking Lord Shivas bow(Here Lord Shiva appears after lord ram).
3.And Lord Shiva and Lord Rudra are not two different persons who lived at different times they are the same person.
4.I did not see the the nagas (Serpents and not the nagas mentioned in th... (Expand)
My first mythological read. I liked the way the author has tried to give a fictitious tale about Lord Shiva. Though the plot doesn't justify the facts of the sacred texts yet on its own it creates a worthy myth. It maintains the glory of the Mahadev (Lord Shiva), but fails to do complete justice... (View complete review)
After reading the Shiva Trilogy, I've finally found hope that Indian authors can write riveting page turners.
Kudos to Amish Tripathi for conceiving and penning such a tale. The trilogy would appeal more to readers with a basic insight into Hindu mythology, while other readers would certainly not... (View complete review)
The imagination of the writer is commendable. He has given a whole new twist to the history of Lord Shiva and that too in addendum to the raised interest of the reader. (View complete review)
I read all the three parts of this series. Hats off to the the imagination of Amish.
Everybody should read it! (View complete review)
Book is very good.Worth reading but the paper quality is bad however full marks to Flipkart and WS Retail for prompt delivery. (View complete review)


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Council leader backs plans for new running track in Darwen (From Lancashire Telegraph)
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Council leader backs plans for new running track in Darwen
3:00pm Tuesday 26th February 2013 in News By Dan Clough, Reporter
THE leader of Blackburn with Darwen Council has backed plans to bring an athletics facility to Darwen.
Coun Kate Hollern said the borough council would do 'all it could' to help set up what would effectively be a running teack and an area for field events, at Blacksnape playing fields.
It comes after the town's MP Jake Berry held a meeting with the man who came up with the idea, former town council deputy chairman Steve Duncan, the council's chief executive Harry Catherall, and athletes from Darwen Dashers running club.
Mr Berry said the chief executive had responded positively to the idea and had said the council would look into it.
Coun Kate Hollern said it was a good idea.
She said: "I would fully support anything that brings new sports facilities into the borough.
"In the current economic climate we are really keen to help others help the borough.
"It would be great if we could bring this facility to Darwen and the council will do all it can to help the people involved."
Mr Duncan originally proposed the idea last August, saying a facility was needed in the town so Darreners didn't have to travel to Witton Park.MP Jake Berry said it was early days but there had been positive talks.
He said: "Mr Catherall said the council would hold discussions to see whether an athletics facility is possible.
"We need to see if the local schools would use it for sports days.
"I hope it is something everyone can get behind but, obviously, we need to work out the costs.
"We want to ensure Darwen gets its Olympic legacy."
Mr Duncan said grant funding was available to cover the majority of costs.
He said: "I look at it like Newrad Fisheries in Watery Lane, which I was involved with.
"We got a Lottery grant and then money started pouring in from all over, and I think that will happen with the athletics facility.
"The infrastructure is already there as it is flat and and the changing rooms are already there.
"The only council money needed should be for an initial feasibilty study.
"My ambition in life is to see a gold postbox in Darwen when a local person wins in the Olympics."
Comments (17)
Please log in to enable comment sorting
4:09pm Tue 26 Feb 13
happycyclist says...
4:38pm Tue 26 Feb 13
ste.g says...
happycyclist wrote:couldnt agree more.
Really? Does Darwen REALLY need an athletics track? Witton Park isn't THAT far away, and is probably nearer to Darwen than some parts of Blackburn are. Use the money to make Witton a venue that the borough can be proud of.
hollern is a pratt and needs to stop squandering tax payers money
4:46pm Tue 26 Feb 13
bril67 says...
11:08pm Tue 26 Feb 13
Councillor Duncan says...
Just imagine if all the bowling clubs, fishing clubs, football clubs etc were to be told all the facilities in Darwen were being withdrawn as facilities existed in Blackburn - there would be an uproar - why should Darreners have to go all the way to Witton Park for a running track!
11:13pm Tue 26 Feb 13
Darwen Malc says...
11:38pm Tue 26 Feb 13
darwenTower says...
Darwen Malc wrote:Seconded.
Well said, Counc Duncan!
1:41am Wed 27 Feb 13
s_smith says...
Laudible as his efforts may be, but to call upon ones former political aspirations - and no doubt whos name shall be seen on a ballot paper somewhere in two months time - is quite distasteful.
9:30am Wed 27 Feb 13
Councillor Duncan says...
9:32am Wed 27 Feb 13
happycyclist says...
Councillor Duncan wrote:Don't patronise me with sarcasm implying that I have reading difficulties, you pompous chump. It doesn't matter where the money comes from if it's still going to be wasted providing something that isn't needed.
(former councillor) obviuosly the 4 people who have commented have reading difficulties as this project does not require local council funding but hopefully will be supported by national Lottery and Sports funding grants. It should actually save local funding as it would be available to local schools in both Darwen and Hoddlesden and surrounding areas. And unless you have a car it is 2 bus routes and at least half an hour each way if you live on the Bolton side of Darwen town centre. The sports field already exists as do changing rooms and shower facilities - let's give the children of Darwen and the surrounding area an athletics facility that does not exist at present.
Just imagine if all the bowling clubs, fishing clubs, football clubs etc were to be told all the facilities in Darwen were being withdrawn as facilities existed in Blackburn - there would be an uproar - why should Darreners have to go all the way to Witton Park for a running track!
"All the way to Witton"! It's a couple of miles down the road, not outer Mongolia.
There are lots of things that Blackburn has got that Darwen hasn't -because Blackburn is a much bigger town.
There are probably more cyclists in Darwen than there are runners, so why not build a velodrome there instead?
This Darwen vs Blackburn pettiness is pathetic. Blackburn hasn't got a gala, a music festival, a tower, a competition swimming pool... and Darwen hasn't got an ice rink, a museum and art gallery, a cinema...
Get over it.
10:35am Wed 27 Feb 13
happycyclist says...
5:29pm Wed 27 Feb 13
penninelad says...
ste.g wrote:Hollern isn't a 'pratt' at all - if you read the article carefuly she hasn't promised one penny never mind 'squandering it'. She said that if the MP and Mr Duncan can up with the funding she'd support it. What's wrong with that ??
happycyclist wrote: Really? Does Darwen REALLY need an athletics track? Witton Park isn't THAT far away, and is probably nearer to Darwen than some parts of Blackburn are. Use the money to make Witton a venue that the borough can be proud of.couldnt agree more. hollern is a pratt and needs to stop squandering tax payers money
5:31pm Wed 27 Feb 13
Major Tom says...
10:56am Thu 28 Feb 13
milano says...
5:16pm Thu 28 Feb 13
district01 says...
So why don't you ask them if they want you to help them Kate!
A running track would be really nice to run around. But surely the moors offer the perfect running track already? But as someone's already mentioned, the car tracks both in Darwen and Blackburn are still a disgrace so priority and effort should go there first!
Question: When is little straw going to replace his father Jack Straw on the safe seat at Blackburn?
7:16pm Thu 28 Feb 13
district01 says...
7:54pm Thu 28 Feb 13
Councillor Duncan says...
(some years ago now) as an example of how funds can be raised. You obviously know nothing about the history of the club, the funding for the top lodge, previous committee members going back some 25-30 years who have all played a part in the club. I suggest you speak to Andy Billington - the current chairperson (who incidently I originally fought to get on the committee - get your facts right and then issue a public apology!!
8:52pm Fri 1 Mar 13
joblogs1 says...
Questions that need to be asked are;
Once the new track is built who will foot the operational cost of the site, Staffing and infastructure(e.g. hurdles)?
Will it be council operated or voluntry group operated?
Who will foot the maintainance cost ongoing for the life of the new track?
What is the demand for such a facility?
The biggest question is why when a far superior alternative already exists in the borough at Witton Park why is it required and/or will it be used at all?
Many athletic clubs outside the borough use Witton has they don't have a facility of there own. We are lucky in the borough to have such a facility already and its not like its over subscribed.
A feasibility study will should examine all this as it says in the report and hopefully conclude that its of no additional benifit.
If lottery bids are being wriiten then improvements to bridleways and footpaths around the Darwen moors would be a better investment and would have a greater benifit to more people and health. Maybe a main path / cycle path improvement scheme to Darwen Tower should be concidered.
Comments are closed on this article.


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|Paulding Chamber to build new park named for Herb Monroe
|Wednesday, November 14, 2012 3:14 PM
By NANCY WHITAKER
Progress Staff Writer
PAULDING – A press conference was held last Wednesday, Nov. 7 by the Paulding Chamber of Commerce announcing the name of a new park, the Herb Monroe Community Park, honoring the longtime community leader who passed away one year ago.
The park will be built at the corner of Main and Jackson streets, at the site of the old Certified gas station. The press conference coincided with demolition of the structure by Kauser Trucking that morning.
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Expired Property Listing
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1/2 price Spectacular 1100 sq ft 2 bdrm luxury condo Next to in Las Vegas
- bedrooms 2
- baths 2
- sleeps 6
- pool yes
- hot tub yes
- pets allowed no
- type Condo
- community
rates (USD)
/ night
$ 999 - $ 999 / week
$ 3,749 - $ 4,000 / month
vacation rental description
Location, location, location. The ultimate location. If you are looking for a spectacular experience look no further. Surrounded by multi million dollar condos there is a diamond in the rough, and you found it. The Jockey Club. This 2 bedroom 2 bath condo is in the perfect location, situated between City Center (One of the United States most talked about construction projects, visually amazing) and the World famous Bellagio, noted for its luxury and elegance and of course the water works show, which the Jockey club has a view of. Across the street is Paris, Planet Hollywood and Ballys.
condo rental amenities
Both bedrooms and Living room are furnished with modern furnishings.
The diamond you have found is the Jockey Club, a modern luxury condo/hotel with 24 hour security, concierge, and a reservation/timeshare center to help book tickets to dining and entertainment.
Jockey Club has a lovely outdoor pool, dining and outdoor sitting area, sauna, hot tub and fully equipped gym.
Guestss of the Jockey Club now have access to some of the amenities of the Cosmopolitan, which is attached to the Jockey club, such as
the pool - a large pool with a great sun deck, lots of lounge chairs, cabanas and a bar.
tennis courts and a large gym
activities and attractions in Las Vegas Nevada
You could spend a lifetime in Las Vegas and never have seen it all. For starters:
The Bellagio has a free Waterworks show within 2 min walk which is spectacular, also they have a gallery of fine art and botanical garden
The Las Vegas strip is filled with non stop action and you will be happy to be right in the middle of it.
We look forward to having you stay with us.
vacation rental rates
2 nights, fri, sat $389
3 nts $549
4 nights $649
5 nights $749
6 nights $849
7 nights $949
Weeknights sunday, mon, tues, wed, thurs
1 night $199
2 nights $259
3 nights $379
4 nigths $499
5 nights $599
All parking, cleaning, taxes and extra fees are included.
There is many dates available.
We prefer to use paypal as it offers the most forms of payments, including most major credit cards and bank transfers. (you do not need a paypal account as we will send you an invoice which is easy to use.)
If you dont wish to use paypal we can take a visa or mastercard over the phone


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Dear Sir,
I am writing to inform you that we intended to install the A/C Units in our warehouse Q3-075. The power required in K.W for indoor and outdoor units is 35.0 K.W, whereas the available power is 24.0 K.W for the air-conditioning, which is not enough .
Our request is that you provide us with 11.0 K.W more for the A/C Units.
Thank you in advance for your understanding.
Faithfully Yours,
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Funding opportunities
Human Embryonic Stem Cells for Incurable Skin Diseases and Chronic Wounds
Funding Type:
Comprehensive Grant
Grant Number:
Funds requested:
$2 215 522
Funding Recommendations:
Not recommended
Grant approved:
Public Abstract:
Human embryonic stem (hES) cells are the first type of human cell cultured in the laboratory that have the potential to become any of the several hundred cell types in the developing gestational human. Wound healing of human skin has been likened to "a recapitulation of gestation". Therefore, if wound healing is like the gestation of a developing infant, it is likely that hES cells could be used to heal chronic skin wounds and provide the many types of cells in human skin with names such as keratinocytes, fibroblasts, endothelial cells, melanocytes and others. Essentially, the wound healing process must fill in a hole in the skin and regenerate skin tissue. Elderly people (especially those with obesity, spinal cord injuries, diabetes, vascular diseases and leg vein diseases) frequently have non-healing skin wounds. The annual cost to care for chronic wounds exceeds $11 billion. Although we think of chronic wounds mainly in elderly adults, there exists a rare genetic disease in children called recessive dystrophic epidermolyis bullosa (RDEB) which causes skin fragility and chronic blistering wounds that heal with scarring. RDEB children die around age 20 – 30 from an aggressive cancer forming in the chronic wounds. The cause of RDEB is a gene defect in a skin collagen called type VII collagen (C7) that makes structures that hold together to two main layers of the skin – the epidermis and dermis. Without this collagen, the epidermis and dermis do not stick together and a chronic blistering wound ensues. We have grafted RDEB skin onto mice and injected the grafts with RDEB gene-corrected fibroblasts and reversed the RDEB in the grafts. Likewise, we have injected into the circulation of the grafted animals RDEB-gene corrected fibroblasts and found that they "home" to the RDEB skin and reverse the RDEB disease. Nevertheless, there are limitations to these cells such as their long-term survival. hES cells are immortal and will continue in the RDEB skin and keep it disease free. Since hES cells are primitive, they will be less likely to be rejected by the host. We will determine their longevity in the host and determine where in the skin these hES cells will reside as they deliver C7 to the skin and wounds. The RDEB hES strategies in this proposal essentially address many of the issues with healing of chronic wounds. We will deliver hES cells to wounded human skin and evaluate where they reside in the healing wound, what connective tissue molecules they deliver to the wound, if there is an acceleration of wound healing and if the wounds heal with less scaring since the hES cells express genes thought to be involved in "scarless" wound healing. Therefore, this proposal will provide insights and possible therapy for an orphan genetic disease in children and chronic, non-healing skin wounds which are an enormous health care problem in the general populaous.
Statement of Benefit to California:
Our proposal has the potential to cure a rare, incurable, genetic, skin blistering disease in children called Recessive Dystrophic Epidermolysis Bullosa (RDEB). Stanford University in Palo Alto has had an EB Registry with many RDEB patients. The care of these children is arduous and a huge economic burden on both the families and the State. To date, the care of these children is only palliative and primitive. Because RDEB is rare, pharmaceutical companies have not invested in RDEB since the market is so small. We hypothesize that RDEB children could be treated with novel strategies based on human embryonic stem cells (hES cells) or hES cells genetically engineered by our laboratory. The main advantage of hES cells is their unlimited reproductive capacity and their primitive nature making them less immunogenic. RDEB is due to a gene defect in type VII collagen (C7) which resides between the two main layers of the skin, the epidermis and the dermis where it is organized into anchoring fibril structures that literally "anchor" the epidermis and dermis together. RDEB children lack a normal complement of functioning anchoring fibrils. Therefore they have poor epidermal-dermal adherence, skin fragility and chronic scarring blistering wounds. We have delivered gene-corrected RDEB fibroblasts into RDEB skin grafted onto mice. The gene-corrected RDEB cells "home" to the RDEB skin grafts and deposit C7 which organizes into anchoring fibrils which corrects the genetic RDEB skin phenotype. There is a RDEB-like C7 knock out mouse that because of wounds in the skin, mouth and esophagus only live 2 – 5 days. We intravenously injected gene- corrected RDEB fibroblasts into these mice and corrected their genetic blistering phenotype. These mice now live more than 2 months. If we had primitive skin cells like those derived from hES cells that artificially express C7 and have a long replicative capacity, these mice might have a normal life span which is one goal in this proposal. The hES technology generated for RDEB can be applied to chronic skin wounds which are an enormous health care problem costing over $11 billion per annum. Our data shows that intravenous administration of cells over-expressing C-7 will "home" to human skin wounds and markedly enhance wound healing. The proposed technology, with the unique regenerative properties of the embryonic dermis present in hES-derived dermal progenitor cells, may help RDEB children and adults with chronic non-healing wounds thus saving considerable health care costs for California.
Review Summary:
SYNOPSIS: This proposal aims to test human Embryonic Stem Cells (hESCs) for their efficacy in treating Recessive Dystrophic Epidermolysis Bullosa (RDEB), an incurable blistering disease that results from a lack of collagen type VII (C7) in the skin. hESC-derived progenitor cells will be obtained from Advanced Cell Technologies (ACT) and transduced with lentivectors to drive C7 expression. Cells will be studied in vitro for their ability to incorporate into human skin cultures and in vivo, using a C7 deficient mouse model, or a xenogeneic model in which human skin (normal or RDEB) is grafted onto immunodeficient mice. IMPACT & SIGNIFICANCE: RDEB is an incurable and fatal disease resulting from a known genetic lesion. This is a rare skin disease that has not received the attention of pharmaceutical companies because the market is small. Literature indicates prevalence rates of ~ 10 to 20 patients per million and the prevalence of epidermolyis bullosa total cases in Japan in one report was only 393 patients. These data give a rough estimate of the number of patients that could benefit from such therapy in California. RDEB is well characterized clinically and pathophysiologically and is due to a defect in type VII collagen and results in blistering wounds in the skin and esophagus which heal by scarring. There is also potential for squamous cell cancer developing at a young age. Success of this project would obviously be significant for RDEB patients, and also could provide a novel approach to treating other chronic skin disorders. The therapies that are being investigated in this project may also be applicable to chronic non-healing skin wounds which are more prevalent and related to venous insufficiency, diabetes, and other causes. There are currently other therapies that have been developed over the years which are used clinically for chronic non-healing skin wounds, including engineered composite tissue grafts. It is important to note that the pathophysiology is different for chronic wounds and RDEB. While this proposal has the specific goal of treating a rare genetic skin with hESC-derived dermal progenitors that have been genetically modified to over-express the missing collagen, a possible extension may be a similar application for chronic wounding for the elderly or diabetics. A more general goal is to test the use of hESC-derived cells as a carrier for gene therapy. Both the specific and general goals would have significant impact. The use of the hESC-derived progenitor cells from ACT is somewhat innovative, but these cells are not adequately described to enable evaluation of their likely relevance to this problem. QUALITY OF THE RESEARCH PLAN: This is a collaborative research plan that aims at developing therapies for a currently incurable skin disease. RDEB patients lack type VII collagen (C7) and as a result develop chronic skin blistering that eventually leads to aggressive, fatal carcinoma. The applicant's previous work in a C7 deficient mouse model of RDEB, and in mouse chimeras harboring human RDEB skin grafts, indicates that provision of C7 via direct intradermal injection or systemic means corrects the blistering phenotype because the C7 can "spontaneously" incorporate in the skin basement membrane. In previous studies, C7 has been delivered by gene-corrected keratinocytes or fibroblasts, which "home" to wounded skin. This proposal will test whether hESCs or their derivatives may be more effective in restoring C7 to RDEB skin, although the rationale for the use of hESCs and the choice of hESC-derived cells is not clearly explained. First, the applicant will generate C7-expressing lentiviral vectors and use these to transduce hESC-derived cells. The hESC-derived cells will be generated by Dr. West at Advanced Cell Technologies. While these are referred to as "dermal progenitor cells", little information is provided about these cells - how were they generated? What is their lifespan? Why were these chosen in particular? etc. In addition, it is unclear what impact C7 over-expression will have on the function and survival of these cells. To assay the therapeutic potential of these cells, the applicant will test their incorporation into in vitro human skin cultures provided by Xgene Corporation, and will assay their ability to hone to human skin after intravenous injection into immunodeficient mice harboring normal or RDEB skin grafts. For the in vivo studies, the cells will be tracked by GFP labeling (via viral transduction). Several different skin graft models will be tested, and tissue will be harvested at short and long timepoints for overall histological evaluation and analysis of GFP+ cell identity. Finally, C7 expressing progenitor cells will be injected into C7-deficient mice to analyze their ability to correct the blistering phenotype and prolong survival. No mention is made of potential problems with immune rejection of the human cells - will the mice be crossed to nu/nu or treated with immunosuppressants? A reviewer considers the major concerns with this study are that the cells the applicant proposes to test in skin repair models are very poorly characterized, and the experiments proposed are not described clearly enough. The application would be greatly improved by the provision of additional, relevant preliminary data about these cells and by reducing the scope of the study to focus on those that demonstrate promise in preliminary studies. A reviewer points out that this proposal builds on the longstanding expertise of the PI in studying experimental therapies for this skin disease. S/he has put together a synergistic group of collaborators which provides a unique opportunity to test the main hypothesis in this proposal, i.e. that hESC-derived skin progenitors can be administered intravenously to correct the gene defect in RDEB. This is a well-written and well-integrated proposal that has important strengths but also several weaknesses. Overall the research plan is carefully laid out and includes preliminary data on the systems used. The research team is a collaboration between two academic scientists with excellent track records in the field, a company with which they have collaborated on human skin equivalents, and a third stem cell company (ACT) that has numerous well-defined subclones of hESC-derived progenitors. However, concern is caused by several important underlying questions: Do the hESC-derived dermal progenitors maintain their stemness/proliferative capacity once in skin tissue, becoming (as implied) slowly dividing stem cells? Or, do they differentiate further and become a limited life span transient amplifying population? Are these hESC-derived dermal progenitors really immunologically stealth as implied? None of these questions are even posed. STRENGTHS: Reviewers highlighted several strengths of this proposal. The project focuses on a currently incurable human disease which is also the primary area of interest of the applicant. In addition, the PI has a track record of collaboration with this research team. The team of collaborators are all experts with unique and complementary technologies and expertise. Synergistic expertise in several different technologies that are established in several different laboratories are brought together. Collaborations with Dr. Michael West of Advanced Cell Technology, Dr. Warren Hoeffler of X-Gene Corporation, and Dr. Woodley of USC's department of dermatology, are organized in a synergistic and unique way providing a beneficial opportunity to study the potential of hESCs for treatment of RDEB. In general, the research plan is well organized and described. Several groups of cell populations including controls are described, and pitfalls and alternative plans are considered. Time course studies are included and multiple independent models are also proposed to be studied. Multiple technologies, models and cell lines are in place to do the proposed studies. Human skin equivalents (HSE), particularly the RDEB HSE model developed by Dr. Warren Hoeffler, are an important strength of the proposal. In addition, the PI has established experience with RDEB animal models and lentiviral vector production. The collaboration with ACT will bring hESC expertise and potentially dermal progenitor cell lines to the proposed studies. In general, the models used (RDEB) mice and their fibroblasts, the human skin equivalents, the lentiviral overexpression of collagen 7) are all well-developed. Another advantage is that the administration of collagen 7 by various means corrects the anchoring of the epidermis to the dermis. The use of GFP marked cells is an important aspect to understanding the mechanisms of the observed effects and for tracking cells. WEAKNESSES: Several weaknesses with the proposal are evident. The rationale for use of hESC-derived cells is unclear. If fibroblasts are so effective (extending lifespan of RDEB model mice from 2 days to 2 months), why not use these? The applicant argues that the fibroblasts are not preferred because they are not maintained, and hESC-derived cells will be longer-lived, but no data is given to support this assertion. They also assert that hESC-derived progenitor cells are less immunogenic than fibroblasts, but again preliminary data is lacking to support this. Proof-of-concept preliminary data is needed to show that hESCs will be longer lived and less immunogenic. In fact, hESCs and their derivatives (dermal progenitor cells) may be more tumorigenic than dermal fibroblasts, a point which is not considered at all in the proposal. Again, proof-of-concept data would provide insurance for a potentially successful outcome. In the absence of these data, the proposal is deemed to be moderately high risk. There is insufficient preliminary data describing the hESC-derived progenitor cell lines identified and isolated by ACT that will be used. The hESC-derived dermal progenitor cell lines are not well characterized. Firstly, it is not proven that these are homogeneous and pure cell populations. Secondly, they have not been characterized for proliferative capacity or developmental potential which are the two hallmarks of progenitor cells. Except for collagen VII expression, and the gene expression profiling at the population level, the cells have not been characterized for gene or protein expression patterns that would be typical of a variety of epidermal and dermal cell types. In addition, the C7 staining and expression pattern is not convincing. Based on the poorly characterized dermal progenitors, the status of each of these six lines that are proposed to be tested is in question and a significant effort should be made to first characterize these lines. There is ambiguity in the research plan. It is not clear which cells will be transduced or at what time, if cells will be pre-selected before assaying, what the impact of C7 over-expression will be on these cells, etc. The applicant provides ample technical detail, but generally does not adequately describe the experimental design and data analysis methods to be used. In the preliminary data, claims are made of improved C7 expression and pathology in RDEB skin, after intravenous injection of C7-modified dermal fibroblasts; however, tracking studies were not performed to demonstrate migration of intravenously administered cells to the skin BMZ layer. Important tracking and mechanistic studies for the effect of intravenously injected cells have not yet been performed in a rigorous way. It is remarkable that there is homogeneous C7 expression in this treatment model. The question arises about if is this dose-dependent, time-dependent, homogeneous expression? Dose dependency studies are not described in the preliminary data nor are they proposed. The data in support of studies proposed on the healing of chronic non-healing skin wounds is weak. There is a modest effect, if one at all, in the human skin equivalent wounding athymic nude mouse model. This minimal effect as shown would probably not be clinically significant. It is not clear why over-expression of C7 would promote healing in this model. In addition, this model may not be predictive of the pathophysiology of chronic non-healing skin wounds as the model uses normal human skin. Important immunological aspects of the study such as the transplantation of human cells into an athymic mouse model where animals retain B cell activity and the possibility of xenograft rejection exists are not considered. In addition, the RDEB C7 knockout mouse model is an immunocompetent model and therefore it is likely that transplantation of human cells will result in immunologic destruction, again, a point that is not considered. The question of whether the hESC-derived progenitors will remain stealth to the immune system is key to the long-term goal but is not addressed. There is comment that in early gestation wound healing is scarless and that these progenitor cells are less immunogenic that post-gestational cells, thus providing the possibility of universal donor cells. If they remain stealth, is there a potential problem with time of tumor formation? Examination of the RDEB mice longer than 18 days after injection may be informative. The question of whether the hESC derived dermal progenitors will maintain their stemness is not examined. If they integrate so well in the skin, one reviewer would expect they would differentiate further rather than "behave like authentic slow cycling skin stem cells to continually generate renewed genetically corrected skin tissue" as described in this proposal. DISCUSSION: As with other applications, there was a question about what the lines from ACT are. The characterization of these lines represents one of the weakest parts of the proposal because while there is transcriptional data, there are no functional data to define the cells. If there are skin progenitors that could be identified from hESC, that would be great for the field. Significant effort should be undertaken at some point to characterize these cell lines; immunocytochemistry, proliferation, makeup, and determination if they give rise to other mesoderm derivations. Preliminary results on hC7 transgenic fibroblasts indicate there is little real benefit from transplanting to diabetic skin lesions (this is considered an extremely weak aspect of study; on the other hand, human skin equivalents are brought together nicely). Also, the GFP-marked cells used for honing is an important aspect of the proposal that was not emphasized. The investigators seem to under-appreciate that they'll have immune activity against these cells. Reviewers were impressed with the team of collaborators and the longstanding experience of PI in this system; the expertise of the PI in the developed RDEB models makes this group uniquely qualified to do this work. The investigators are working with a nice, well-developed system to test issues, albeit only a small population of people has this disease. Finally, it is not clear that results with mice will translate to humans.


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West Aurora players smile with excitement after taking second place in the Pontiac Holiday Tournament. | Patrick Gleason~For Sun-Times Media
West Aurora may be leaving the DuPage Valley Conference and joining the Upstate Eight for the 2014-15 school year.
The West Aurora School Board voted unanimously Monday night to allow West Aurora High School to accept the invitation of membership from the Upstate Eight Conference, pending resolution of several issues.
Whether the high school accepts the invitation will depend on whether the Glenbard Township High School District 87 board votes to permit Glenbard East High School to also accept its invitation to join the Upstate Eight.
The Upstate Eight's invitation is intended to build a conference with an even number of teams. A decision from Glenbard East may not be finalized until February.
Even though School Board President Neal Ormond voted for the conference change, ultimately he wanted to see a shift that would benefit all the schools in both the DVC and Upstate Eight.
"The ideal world would have all the parties sitting down individually," he said.
Ormond said he is concerned about voting on something that ties the fate of West to a decision that another school makes. Should Glenbard East decide not to join the Upstate Eight, West Aurora would not be able to join. In that scenario, West would not leave the DVC.
Ormond also raised concerns that the Upstate Eight schedules more weekday boys basketball games than the DVC — a policy that could come with a financial impact. He also wants to make sure there are opportunities for all the different levels of teams that West Aurora offers.
There also is a possibility the DuPage Valley Conference could delay West's exit for another year, in which case they would not be able to join the Upstate Eight until the 2015-16 school year.
West High Athletic Director Jason Buckley and Activities Director Whitney Martino conducted surveys over the last few months, showing that a majority of the high school coaches favored the move. Both said it would make West more competitive in athletics.
Student board member Chase Woods wanted to stress that the conference shift had a broad, positive impact.
"From who I talked to, there's a big misconception that we're doing this for two or three teams," Woods said.
West Aurora was a charter member of the Upstate Eight in 1963.
The district left the conference after the 1996-1997 school year, and joined the DVC for the 1997-98 school year.
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Varsity: Cumberland Valley 36, CAMS North 31. For North (1-1), Collin Browning tallied 14 points and Jayden Doctor had 5.
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AZLE -- In the hallways of Azle High School, there's a senior that brings out the best in students.
"I love her," said senior Bobbi Jo Sisk. "She's like my best friend. She is so awesome. She has a great personality."
The student is Alejandrina Guzman. The 17 year old zooms in her wheelchair from class to class with ease. She was born with several disabilities, including a cleft palate, club feet, and dwarfism.
"When you look at her, there is something different there, but in the end, there is nothing different," said Azle High School Principal Sam Robinson. "She is like everybody else, if not exceptionally higher than them, because of her personality, her wit and the way she does in school -- her academic achievements."
Alejandrina is an honors student, elementary school mentor and a "rowdy" spirit squad member. She's now in the running for homecoming queen.
"To me, it's a surprise, because it just shows how much Azle High School thinks of others," Alejandrina said. "It shows the ability to look past the outside, and how the inside really matters."
Her principal and classmates see beyond her disabilities. They see courage.
"She has taught me that there are no limitations, that anything can be done by anyone," Robinson said. "Nothing stops Allie. So why should anything stop me?"
In Azle and on the internet, Alejandrina is taking her message to the masses. She has posted inspirational videos sprinkled with wit and wisdom, and her Twitter feed is full of positive messages.
She's helping people find beauty in life's obstacles.
"I just wanted to speak out and send a message to others that they can do it," the senior said. "They are here for a reason."
Alejandrina mentioned that she gets her strength to take on challenges from her mother, father, other family members, and friends.
Currently, she isn't video blogging, because she's focused on her next challenge: college. University of Texas in Austin is her first choice.
She worries about going away to school without her loyal team of family and friends, but she's staying positive.
"I see my future is bright, just as long as I keep trying and never give up," she said.
So homecoming queen or not, Alejandrina knows she has already scored a victory.
"It makes me feel good, because I know I have done something besides having a disability," she said. "I know that I have shown my inner, my true self instead of the wheelchair and me."
The homecoming results will be announced a week from Friday.
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(First I would like to say Hi because I am returning here after a long break so sorry about that. Second I just thought id provide this here for you guys instead of just a link to it on the site I am doing it for)
The season is here, so naturally it is time to look ahead to the playoffs. No? This eight-part series takes a look at each division and discusses the outlook for every team in the NFL — in both the regular season and playoffs.
Christian Petersen | Getty Images
TEAM: San Diego Chargers
RECORD: 12-4 | Win the Division
REASON: Although the Chargers appeared to be a team on the decline last year, that should change in 2010. Their defense is still respectable, although they do have some concerns along the defensive line. Offensively, the Chargers have lost LaDainian Tomlinson, once the best rusher in the league, but one who seems to have lost his legs. They drafted running back Ryan Matthews to replace Tomlinson, who should reinvigorate their ground game, so long as their offensive line can hold up. The biggest advantage for the Chargers over the rest of their division is the play of quarterback Phillip Rivers.
TEAM: Kansas City Chiefs
RECORD: 8-8 | No Playoffs
REASON: The Chiefs are getting better, but it is a slow process. This off-season they upgraded the defense by picking up safety Eric Berry in the NFL Draft. Offensively the Chiefs have big holes at tight end, wide receiver, and quarterback. They will need to find a go-to receiver to help out quarterback Matt Cassel who they added from the Patriots last year. While the Chiefs expected Cassel to give the team a real life, he failed to live up to expectations in 2009.
TEAM: Denver Broncos
RECORD: 6-10 | No Playoffs
REASON: The Broncos are a difficult team to forecast. They have an average quarterback who is capable of winning but if last year is an indication, he tends to fall off halfway through the season. The Broncos have an good stable of running backs, which would promise a strong ground game, but they are all starting the season injured. Their biggest off-season acquisition came through the draft, when head coach Josh McDaniels opted to select Tim Tebow in the first round. The only problem is that he is not projected to have an immediate impact this season. Unable to get players who will immediately upgrade the team in the first round it is hard to think this team is destined to improve.
TEAM: Oakland Raiders
RECORD: 5-11 | No Playoffs (though they may improve)
REASON: The Raiders have improved a lot in the off-season, with the release of quarterback Jamarcus Russell and the trade to get quarterback Jason Campbell from Washington. Campbell is capable of taking Oakland to eight or more wins. Since Campbell's arrival, Darrius-Heyward Bay has caught almost everything thrown to him, which foretells a vast improvement over nine receptions in 2009. The Raiders have built a solid defense but still have big questions along the offensive line.


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An ecological mystery in Alaska has scientists and fishermen baffled and alarmed.by Ben Goldfarb, Jul 07, 2014
Reflecting on groundwater from the Owens Valley Watershed
Growing up in the high desert, I learned water doesn't just fall from the sky.by Ceal Klingler, Jul 06, 2014
What makes America unique is its public landsby Jamie Williams, Jul 03, 2014
Divers explore national parks' underwater treasures
The last frontier of the national parks lies underwater.by Katie Mast, Jul 02, 2014
Consider the names this July 4thby Diane Sylvain, Jul 01, 2014
'A pimp in the family'
After years of being preyed upon by payday lenders, tribes get into the game themselves.by Jonathan Thompson, Jul 01, 2014
River of no return
Seattle's Duwamish has been straightened, dredged and heavily polluted. Can a Superfund cleanup bring it back to life?by Daniel Person, Jul 01, 2014
About those gay loggers for Jesus and July 4thby Brian Leland, Jun 26, 2014


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Entertainment Design
, the magazine dedicated to the design professional, has announced this year's Staging and Projection Product of the Year honorees. The five winners, picked by a panel of projection and staging specialists, will be honored at this year's EDDY Awards, to be held Friday, June 18 at John Jay College Theatre in New York.
The winners, which will be featured in the April issue of ED, are:
Barco MiPIX Intelligent LED Pixel Block
"The Barco MiPIX breaks the mold for LED imaging with separation and shaping," say the judges. "The MiPix offers designers a flexibility for screen shape that goes all the way to 3D and see-through."
High End Systems Catalyst DL1 Digital Light
"With big bonuses like dimming irises (goodbye video black!), and High End's robust stepper motor technology inserted into the lens train," say the judges, "this is not your daddy's projector."
Hoffend and Sons Vortek Rigging System
"Vortek has not only managed to make motorized pipes intelligent, but it may also spell the end of counterweight rigging, a feat that cannot be overestimated," say the judges.
Stage Technologies Visual Creator Software
This "remarkably intuitive" 3D visualization software "greatly expands the notion of what can be moved where on the stage," say the judges.
Vista Systems Montage Video Processor
"With all of the functionality and tactile surfaces found on a powerful broadcast video switcher," say the judges, "this unit offers programmers a totally superior mode of working."


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There was a wonderful Twitterrific flury of activity Friday night, when a) B.J. Upton was pulled from the Rays' game against the Royals for no apparent reason, and b) prospect Desmond Jennings was scratched from the Triple-A Durham Bulls' lineup.
Has to be a trade, right? With Jennings taking over for Upton in center field?
Alas, the truth (so far) is somewhat less dramatic. Tampa Bay shortstop Reid Brignac, in the middle of an absolutely terrible season, has been demoted to Durham; that's whose roster spot Jennings is getting.
Upton might still be traded, of course. But for the moment it looks like Jennings will simply join the outfield mix, along with Upton, Matt Joyce, and Sam Fuld (who's been pretty good since his legendary April and nightmarish May).
Jennings, one of the Rays' top prospects for some years now, was hitting .275/.374/.456 with Durham. Speed and defense are big parts of Jennings' game, and he's swiped 17 bases in 18 attempts for the Bulls after going 37 for 41 last year.
Elliot Johnson probably takes over at shortstop; Johnson's batting .197 but has showed some power, which is a lot more than Brignac can say this season.
There's probably more to this story, as we still haven't heard why Upton was pulled from the game Friday night. Stay tuned...


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Tredegar's Mark Colbourne chases third Paralympic medal (From South Wales Argus)
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Tredegar's Mark Colbourne chases third Paralympic medal
10:25am Wednesday 5th September 2012 in News
TREDEGAR paracyclist Mark Colbourne will go for his third medal at the London 2012 games today, knowing he has the full backing of the Valleys charity he used to work for.
He was roared home to gold last Friday by excited volunteers at the Hospice of the Valleys, the charity based in his home town that both he and his late father, Cecil, supported.
Mark worked as a fundraiser for the charity for 18 months from 2003, arranging two of the hospice's annual Lap of the Lake fun runs, which take place around Bryn Bach Park lake in Tredegar, and raises around £10,000 for the hospice annually.
Helping out at the hospice has been a real family affair, with Mark's late father, Cecil, who died in February of stomach cancer, being fondly remembered by staff at the charity.
Cecil signed up as a volunteer when Mark joined the team.
He drove a van around Blaenau Gwent for almost ten years, collecting donated items and delivering them to the chain of charity shops, and last year played a large part in helping to get the hospice's new shop in Ebbw Vale open on schedule. Just months later, though, he became ill with cancer and was himself a patient at the hospice.
After taking gold on Friday Mark dedicated his win to his father, who he had previously described to the Argus as his best friend.
Helen Morgan, fundraiser for the hospice, who worked with Cecil for several years, added: "Cecil was devoted to his only son and often talked of his bravery in overcoming his injuries after the paragliding accident.
"He was very proud of Mark's achievements ."
Miss Morgan said the whole team had listened to his win on the radio and were looking forward to welcoming him back to Tredegar.
Comments are closed on this article.


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SHERMAN, TX -- More than two dozen new stop signs could be coming to a neighborhood near Sherman High School, and some residents say they support the plan.
The city engineering department wants to spend $5,000 dollars to put up the signs at more than a dozen intersections in the neighborhood just west of Sherman High School.
Some of the intersections currently have yield signs, but under the new plan, 33 new stop signs would go up in the area.
Neighbors say that area along East Mulberry and Pecan Streets near the intersection of Burdette and Andrews often gets busy on school days. The Sherman City Council will consider the plan at their meeting on Monday.


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Getting Misty
Photograph from NASA via Reuters
Sitting on a rolling platform, the space shuttle Challenger emerges from the mist at Kennedy Space Center in Florida as it heads toward the launch pad, just visible in the distance, in November 1982. Challenger lifted off on its maiden voyage in April 1983 for the sixth shuttle mission.
When the space shuttle Atlantis lands on Thursday, it will wrap up STS-135, the final shuttle mission in the U.S. program's 30-year history. This shot is among those chosen by National Geographic photo editors as the most unforgettable pictures from the entire shuttle program.
Even with the tragic losses of Challenger and Columbia, the space shuttle has become an icon among U.S. science and technology achievements. During the past three decades, shuttles carried the first U.S. woman and the first African American into space, deployed famous satellites such as the Hubble Space Telescope, and delivered valuable parts and supplies to the International Space Station (ISS).
"The space shuttle has been with us at the heart and soul of the human spaceflight program for about 30 years, and it's a little sad to see it go away," STS-135 mission commander Christopher Ferguson recently told reporters in a televised interview from the ISS.
"It's going to be an emotional moment for a lot of people that dedicated their lives to the shuttle program for 30 years. But we're going to try to keep it upbeat ... We're going to try to make it a celebration of the tremendous crowning achievements that have occurred."
Published July 20, 2011
American Woman
Photograph courtesy NASA
Astronaut Sally Ride floats in front of the control panels for the space shuttle Challenger on June 25, 1983, while serving as a mission specialist for STS-7. Ride became the first U.S. woman in space during this mission.
Published July 20, 2011
Starry Night
Photograph courtesy NASA
The space shuttle Endeavour—payload bay doors ajar—rushes past Earth while docked to the International Space Station on May 28, 2011.
(See pictures from the final flight of Endeavour.)
Published July 20, 2011
Hubble Huggers
Photograph courtesy NASA
Astronauts John M. Grunsfeld (right) and Richard M. Linnehan stand next to the Hubble Space Telescope, which was brought into the space shuttle Columbia's payload bay for repairs during STS-109, as seen on March 8, 2002.
(Related: "Shuttle Crew on Hairy Hubble Mission, Humans vs. Robots.")
Published July 20, 2011
Earning Its Stripes
Photograph courtesy NASA
Suspended above the planet, the space shuttle Endeavour is silhouetted against the layers of Earth's atmosphere in a picture taken by an ISS crew member on February 9, 2010. The shot shows the shuttle shortly before it docked with the space station during STS-130.
(Related pictures: "Twenty Stunning Shots of Earth From Space.")
Published July 20, 2011
Two Satellites, Slightly Used
Photograph from NASA via Reuters
Seen outside the space shuttle Discovery during STS-51-A, astronaut Dale Gardner enjoys a moment of levity as he completes a spacewalk to recover two broken communications satellites from orbit on November 14, 1984. Astronaut Joseph P. Allen IV is seen reflected in Gardner's helmet visor.
(Also see "Space Shuttle 'Retirement Homes' Announced.")
Published July 20, 2011
First to Launch
Photograph courtesy NASA
The space shuttle Columbia sits on a launch pad at Kennedy Space Center on March 5, 1981. Columbia launched on the first shuttle flight, STS-1, on April 12, 1981. (Read "When the Space Shuttle Finally Flies" from the March 1981 issue of National Geographic magazine.)
Following the first two launches, NASA calculated that they could safely shave 600 pounds (272 kilograms) from a shuttle's overall launch weight by not painting the large external fuel tank white and instead leaving its orange insulating foam exposed.
Published July 20, 2011
Lighting the Night
Photograph by Joe Raedle, Getty Images
A softly glowing plume is all that remains visible of the space shuttle Endeavour after a nighttime launch from Florida's Kennedy Space Center on March 11, 2008.
(Related: "Tunguksa Blast Mystery Solved by Space Shuttle?")
Published July 20, 2011
Enterprise Crew
Photograph from AP
Originally slated to bear the name Constitution, the first space shuttle to be built was dubbed Enterprise following a write-in campaign from Star Trek fans. Above, cast members from the science-fiction show attend the shuttle's rollout ceremony in Palmdale, California, on September 17, 1976.
From left to right: Leonard Nimoy, who portrayed Vulcan science officer Spock; George Takei, who was helmsman Hikaru Sulu; DeForest Kelly, who was chief medical officer Leonard "Bones" McCoy; and James Doohan, who was chief engineer Montgomery "Scotty" Scott.
(Also see "Star Trek's New Ship: It's Not Your Grandfather's Enterprise" in the National Geographic magazine blog Pop Omnivore.)
Published July 20, 2011
Launch Lovers
Photograph by Shawn Thew, European Pressphoto Agency
Spectators gather in the late-morning heat to watch the space shuttle Atlantis lift off for STS-135, the final shuttle mission, on July 8, 2011.
(Watch NASA video of the final shuttle launch.)
Published July 20, 2011
Tragedy Strikes
Photograph from AP
A cloud of debris spreads in the sky over coastal Florida as the space shuttle Challenger breaks apart on January 28, 1986. The orbiter disintegrated 74 seconds after launch during STS-51-L, killing all seven crew members.
(See pictures: "Five Myths of Challenger Shuttle Disaster Debunked.")
Published July 20, 2011
Global Reach
Photograph courtesy NASA
Earth seems ready for loading into the space shuttle Endeavour's open payload bay in a picture taken in December 1998 using an onboard IMAX camera. The large-format camera was sent into space during STS-88 in part to film the installation of the Unity Node, the first U.S. module for the International Space Station.
(Get a review and see footage from the IMAX movie Hubble 3-D.)
Published July 20, 2011
Exposed Engine
Photograph by Jon T. Schneeberger, National Geographic
Technicians work on a test firing of a space shuttle main engine at the National Space Technology Laboratories in Bay St. Louis, Mississippi, before the first flight of Columbia in 1981. (See more behind-the-scenes pictures from the first shuttle launch.)
Published July 20, 2011
All Hands on Deck
Photograph courtesy NASA
The crew of STS-102 works on the flight deck of the space shuttle Discovery to dock the shuttle with the International Space Station on March 10, 2001.
Published July 20, 2011
Parachute Check
Photograph by Jon T. Schneeberger, National Geographic
A technician inspects one of the nylon parachutes used to slow the descent of a space shuttle's solid rocket boosters before STS-1 in 1981. The 80-ton rockets detached shortly after launch and splashed down in the Atlantic Ocean, where they were recovered for reuse.
Published July 20, 2011
Big Apple Shuttle
Photograph by Richard Drew, AP
Riding piggyback on a Boeing 747, the test shuttle Enterprise glides over the New York City skyline in June 1983. Unable to fly like airplanes under their own power, shuttle orbiters had to be transported long distances atop of other aircraft.
(See more rare behind-the-scenes views of the space shuttle.)
Published July 20, 2011
Florida Twister
Photograph by Wilfredo Lee, AP
A tornado forms a dark column near the launch pad, where the space shuttle Columbia waits to launch on STS-93, as seen on July 20, 1999. The shuttle lifted off July 23, carrying NASA's Chandra X-ray Observatory into orbit.
Published July 20, 2011
Mission Control
Photograph courtesy NASA
Staff at the Mission Control Center of Johnson Space Center in Houston, Texas, monitor the landing of the space shuttle Columbia on April 14, 1981, after the first ever shuttle mission to reach orbit.
Published July 20, 2011
Plume Tendrils
Photograph courtesy NASA
Curling like bizarre sigils in the sky, plume remnants from the June 8, 2007, launch of the space shuttle Atlantis glow with the light of the setting sun. The so-called night-shining clouds created by the launch are seen over the Vehicle Assembly Building, or VAB.
(Related pictures: "'Night Shining' Clouds Getting Brighter.")
Published July 20, 2011
Hanging Out
Photograph courtesy NASA
Seen from the space shuttle's payload bay, astronaut Mark Lee goes for an untethered spacewalk outside Discovery in September 1994.
(Related: "Shuttle Astronaut's Four Most Extraordinary Moments.")
Published July 20, 2011
Line Up for Landing
Photograph courtesy NASA
A huge crowd—many driving recreational vehicles—gathers to watch the space shuttle Columbia land on July 4, 1982, at Edwards Air Force Base in California at the end of STS-4.
Published July 20, 2011
Grim Legacy
Photograph by Christine S. Diamond, Lufkin Daily News/AFP/Getty Images
A charred astronaut helmet lying in the grass near Norwood, Texas, was among the debris found after the space shuttle Columbia broke apart during reentry on February 1, 2003. The orbiter had completed STS-107 and was returning for landing, but damaged heat shielding caused the craft to disintegrate, killing all seven crew members.
Published July 20, 2011
Uplifting Sight
Photograph by Scott Audette, Reuters
In preparation for STS-135, the space shuttle Atlantis is lifted high inside the Vehicle Assembly Building on May 18, 2011, so it can be attached to the "stack"—the combination of the large external fuel tank and twin solid rocket boosters.
Published July 20, 2011
Southern Comfort
Photograph courtesy NASA
The gentle green glow of the aurora australis—or southern lights—curls over Earth in a picture taken by an astronaut aboard the space shuttle Discovery on August 6, 2005.
Published July 20, 2011
Pool Cues
Photograph courtesy NASA
Like a delicate water ballet, astronauts practice for a shuttle mission on December 10, 1997, in the Sonny Carter Training Facility—a giant swimming pool filled with life-size replicas of space hardware—at the Johnson Space Center in Houston, Texas.
Published July 20, 2011
Surfin' U.S.A.
Photograph by Duffin McGee, Reuters
Cocoa Beach surfers watch from the water as the space shuttle Atlantis lifts off from nearby Kennedy Space Center in Florida on September 8, 2000.
Next: "After Space Shuttle, Does U.S. Have a Future in Space?" >>
Published July 20, 2011
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Who's Afraid of Science?
Learning about science has taught me humility about my Bible reading and it has pushed me to think again, to read again, to ask again, and to wonder all over again what the Bible was saying when it was written and how the Bible was heard to its original hearers (so far as the evidence permits us to know such things).
Origins News Roundup for July 23, 2014
This week in origins news, a great collection of articles by key players in the conversation about theology and science, a surprising science fair discovery, and the Apollo 11 anniversary!
Creation Unfolding: Reading Genesis in a Historical Setting
For my part, the historical setting of the text plays an important role in how I read. It's not a problem in my view to see the authors of Genesis embedded in their times, writing in the scientific/mythological terms they knew, even if those terms are now obsolete.
Video repost: Chris Tilling on Biblical Genre and Relational Truths
"There are clues in a text as to how the text should be written, so with Genesis, the rhythmic nature of Genesis 1 and 2, the almost poetic, and hymnic, function that it would have played in the liturgy of the earliest Jewish lives… it seems to me that there are clues here that it should be read in a theological way."
Interview with Ronald Osborn
We must press beyond the various creation narratives in the Hebrew Bible, including the final chapters of Job, to the picture of God revealed in the New Testament—the Creator who does not rationally explain away the scandal of suffering but who instead enters into it.
A Review of "Death Before the Fall: Biblical Literalism and the Problem of Animal Suffering" by Ronald E. Osborn
The confident assertion that the Bible trumps science stems from a misunderstanding of the purpose of the scriptures, and a misapplication of the Bible to answer questions that can only be answered by the application of science.
"The Language of God" Book Club–Chapter 6
How should we interpret the Bible? What is the role of tradition? What is the role of science? Who gets to decide whether traditional interpretations need to change?
Confessions of an Evolving Baptist
"Being confronted with evolution may have been the catalyst for asking the difficult questions, but the real problem for me was not evolution – it was biblical literalism."
Biblical Credibility and Joshua 10: What Does the Text Really Claim?
Once we recognize that no one takes the text literally, and that we have often failed to account for the details in the text regarding the time of day, we can begin anew to try to understand the text as an ancient text rather than as a modern one. As such, we must begin with the idea that the text operates in the world of omens, not the world of physics and astronomy.
God's Extravagant Love in Creation
Critics of Christianity look to evolution to show how the emergence of human life on earth demanded enormous ruin and ravage, billions of years of apparent waste and futility, species extermination and organism road kill. Not only was the massive dying off rampant, it's mandatory too.
Series: Apologetic Issues in the Old Testament (3 entries)
This series, by Old Testament scholar Richard S. Hess, was first published as an appendix to Christian Apologetics: A Comprehensive Case for Biblical Faith (Downers Grove: IVP Academic; Nottingham: Apollos, 2011).
Series: Excerpts from "Evolving: Evangelicals Reflect on Evolution" (13 entries)
We need to hear stories from others who have wrestled with evolution and Christian faith. What arguments made them change their views on science? How did they hold fast to their relationship with God? The essays in this series will eventually comprise a book, provisionally titled, "Evolving: Evangelicals Reflect on Evolution."
Hydrology of the Bow River
There's a word beneath the water, and the Bow River belongs to God. Have you been listening?
A Scientific Commentary on Genesis 7:11
Although committed to the principle of sola Scriptura, Calvin recognized that the Bible would have been written in terms its original recipients would have understood. Calvin inherited the medieval cosmology of his time, a way of viewing the world heavily influenced by Greek thought and one which was about to receive shocks from astronomers such as Copernicus and Galileo. But not just yet.
Series: It's an Old World After All (2 entries)
In our sixth BioLogos videocast, we take a look at the age of the Earth. We explain four methods scientists have used to determine that age: tree ring, lake varve, radiometric, and seafloor spread dating, and also offer some theological insight on how an old earth can fit with the first chapters of Genesis.
How Do We Know the Earth is Old? (Infographic)
The BioLogos Forum is pleased to present this infographic about the tools scientists use to determine the age of the Earth. The graphic, titled "How Do We Know the Earth is Old?", uses data compiled and summarized by geology professor Dr. Gregg Davidson.
The Questions Update: The Age of the Earth
We've recently been looking at the evidence for an old earth and the long history and vibrancy of this view among evangelical Christians. Today's post features a preview of the updated Question, "How are the ages of the Earth and universe calculated?" revised by Senior Web Consultant and Writer Deborah Haarsma.
Saturday Sermon: Over and Above Naturalism, Part 2
Barkley suggests that material creation is not the end of our understanding (as Naturalists think), but a beginning that unveils the majestic and power of a Creator who loves us.
Saturday Sermon: Over and Above Naturalism
Pastor Joseph Barkley of Ecclesia Church extols the greatness of the God who has brought forth incredible works and engaged humankind in relationship. In the first part of the sermon "Over and Above Naturalism," Barkley admires the factual knowledge unlocked by science, and yet reminds the Church that those material descriptions fail to answer the question of ultimate significance.