text:
The cover picture shows the binding of a PLHSpT derivative, 6q, to the polo-like
kinase 1 (Plk1) polo-box domain (PBD), thereby uncovering a new hydrophobic channel
(magnified upper right), which is absent in the unliganded protein (magnified lower
left). The authors explain how, as a consequence of the additional interaction with
the channel, the peptide binds to the Plk1 PBD with a binding affinity more than
two orders of magnitude higher. The background image of a stained cell nucleus depicts
how this binding results in interference with Plk1 (red dots)-dependent bipolar
spindle formation (green), and this ultimately leads to mitotic block and apoptotic
cell death in cultured cancer cells. See: Peptoid–Peptide Hybrid Ligands
Targeting the Polo Box Domain of Polo-Like Kinase 1k by Fa Liu,
Jung-Eun Park, Wen-Jian Qian, Dan Lim, Andrej Scharow, Thorsten Berg, Michael B.
Yaffe, Kyung S. Lee*, and Terrence R. Burke Jr., in the ChemBioChem ,
2012, 13, 1291-1296.
A Better Fit. An improved anticoagulant drug called RUC-2 (ball and stick structure)
fits snugly into its binding pocket on integrin (blue), a protein found on the surface
of platelets. RUC-2 binds both subunits of integrin, inhibiting the excessive blood
coagulation that can lead to strokes and heart attacks. Unlike similar drugs that
alter integrin's structure when they bind and trigger unwanted immune responses,
RUC-2 does not disturb the configuration of its larger partner. See: Structure-Guided
Design of a High-Affinity Platelet Integrin αIIbβ3 Receptor Antagonist That Disrupts
Mg2+ Binding to the MIDAS by Jieqing Zhu, Won-Seok Choi, Joshua
G. McCoy, Ana Negri, Jianghai Zhu, Sarasija Naini, Jihong Li, Min Shen, Wenwei Huang,
Daniel Bougie, Mark Rasmussen, Richard Aster, Craig J. Thomas, Marta Filizola, Timothy
A. Springer and Barry S. Coller in the Science Translational Medicine,
2012, 4(125), 125ra32. [CREDIT: C. BICKEL/SCIENCE TRANSLATIONAL
Beginning with a known 3-oxabicyclo[3.1.0]-hexane scaffold, the relocation of the
fused cyclopropane ring bond and the shifting of the oxygen atom to an alternative
location engendered a new 2-oxabicyclo[3.1.0]hexane template that mimics more closely
the tetrahydrofuran ring of conventional nucleosides. The synthesis of this new
class of locked nucleosides involved a novel approach that required the isocyanate
with a hydroxyl-protected scaffold as a pivotal intermediate that was obtained in
11 steps from a known dihydrofuran precursor. See: Synthesis of Conformationally
North-Locked Pyrimidine Nucleosides Built on an Oxabicyclo[3.1.0]hexane Scaffold
by Olaf R. Ludek and Victor E. Marquez in the Journal of Organic Chemistry,
2012, 77(1), 815-824.
In silico-generated hypothetical interactions of a ring-closing metathesis-macrocylized
peptide bound to the amino terminal SH3 domain of the growth factor receptor bound
protein 2 (Grb2). The complex was derived from the NMR solution structure of the
bound parent peptide, Ac-V-P-P-P-V-P-P-R-R-R-amide (Protein Data Bank: 3GBQ). The
protein surface is shown as electrostatic potential (blue = positive; red = negative).
See: Application of Ring-Closing Metathesis to Grb2 SH3 Domain-Binding Peptides
by Fa Liu, Alessio Giubellino, Philip C. Simister, Wenjian Qian, Michael C. Giano,
Stephan M. Feller, Donald P. Bottaro and Terrence R. Burke Jr. in Peptide Science,
2011, 96 (6), 780–788.
Bridging bioinorganic chemistry with asymmetric synthesis: a naturally occurring
metalloprotein is used for the structure-based evolution of chiral auxiliaries that
prove to be effective in the synthesis of Fmoc-L-γ-carboxyglutamic acid. See
Enhanced Stereoselectivity of a Cu(II) Complex Chiral Auxiliary in the Synthesis
of Fmoc-L-γ-carboxyglutamic Acid by Daniel Smith, Glenn Yap,
James Kelley and Joel Schneider in the Journal of Organic Chemistry,
2011, 76 (6), pp 1513–1520.
The inside cover picture shows how siRNAs modified with North bicyclo[3.1.0]hexane
2'-deoxy-pseudosugars are able to activate the RNA interference machinery. The paper
confirms that the North conformation is critical for RNAi activity. For further
details, see Effect of North Bicyclo[3.1.0]hexane 2'-Deoxypseudosugars on
RNA Interference: A Novel Class of siRNA Modification by Montserrat
Terrazas, Sandra M. Ocampo, José Carlos Perales, Victor E. Marquez and Ramon Eritja
in ChemBioChem 2011, 12 (7), 1056 – 1065.
The inside cover picture shows the molecular structure of a DAG lactone derivative
on top of the inner leaflet of a DMPC bilayer. The confocal microscopy image illustrates
DAG-lactone-stimulated membrane localization of PKCδ-ECFP in living cells, while
the space-filling model shows the surface of the C1B domain of PKCδ, the target
of the lactone. For more information, see: Membrane-Surface Anchoring of
Charged Diacylglycerol-Lactones Correlates with Biological Activities
by Or Raifman, Sofiya Kolusheva, Said El Kazzouli, Dina M. Sigano, Noemi Kedei,
Nancy E. Lewin, Ruben Lopez-Nicolas, Ana Ortiz-Espin, Juan C. Gomez-Fernandez, Peter
M. Blumberg, Victor E. Marquez, Senena Corbalan-Garcia and Raz Jelinek in ChemBioChem
2010, 11 (14), 2003-2009.
The picture shows the locked north (blue) and south (red) bicyclo[3.1.0]hexane nucleosides
in the normal pseudorotational cycle, and the corresponding shift to a smaller cycle
(nmax=7°) caused by the insertion of a double bond. The former nucleosides are inactive,
while the flattening of the embedded cyclopentene ring provides active compounds
against HOS cells infected with HIV. See: North- and South-Bicyclo[3.1.0]Hexene
Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity
by Pamela L. Russ, Maria J. Gonzalez-Moa, B. Christie Vu, Dina M. Sigano, James
A. Kelley, Christopher C. Lai, Jeffrey R. Deschamps, Stephen H. Hughes and Victor
E. Marquez in ChemMedChem 2009, 4 (8), 1354 -
The lowest energy-binding conformation of an inhibitor bound to the dimeric interface
of HIV-1 integrase core domain. The yellow region represents a unique allosteric
binding site identified by affinity labeling and mass spectrometry and validated
through mutagenesis. This site can provide a potential platform for the rational
design of inhibitors selective for disruption of integrase multimerization. See:
Discovery of a small-molecule HIV-1 integrase inhibitor-binding site
by Laith Q. Al-Mawsawi, Valery Fikkert, Raveendra Dayam, Myriam Witvrouw, Terrence
R. Burke, Jr., Christoph H. Borchers and Nouri Neamati in PNAS 2006,
103 (26), 10080-10085.
Interaction of the β-L-enantiomer of a 4'-C-ethynyl-2',3'-dideoxynucleoside analogue
(ent-14-TP) at the active site of HIV reverse transcriptase. See: A 4'-C-Ethynyl-2',3'-Dideoxynucleoside
Analogue Highlights the Role of the 3'-OH in Anti-HIV Active 4'-C-Ethynyl-2'-deoxy
Nucleosides by Maqbool A. Siddiqui, Stephen H. Hughes, Paul L.
Boyer, Hiroaki Mitsuya, Que N. Van, Clifford George, Stefan G. Sarafinanos, and
Victor E. Marquez in the Journal of Medicinal Chemistry 2004,
47, 5041-5048.
HHAI methyltransferase (blue ribbon) bound to oligonucleotide (strands with bonds
colored yellow and green) containing a pseudorotationally constrained sugar analogue
at the target position (orange bonds with cyan atoms). The south-constrained pseudosugar
is rotated about its flanking phosphodiester bonds, 90° from its initial position
in B-form DNA, but short of a completely flipped position with 180° rotation. Thus,
it is trapped in the middle of the flipping pathway via the major groove side. This
structure provides clues to DNA-protein interactions in a potential transition state.
See: Caught in the act: visualization of an intermediate in the DNA base-flipping
pathway induced by HhaI methyltransferase by John R. Horton, Gary
Ratner, Nilesh K. Banavali, Niu Huang, Yongseok Choi, Martin A. Maier, Victor E.
Marquez, Alexander D. MacKerell Jr and Xiaodong Cheng in Nucleic Acids Res.
2004, 32 (13), 3877–3886.
The scheme depicts a possible mechanism of cross-linking by erbstatin and related
analogues. A mechanism of action is proposed which involves initial oxidation to
reactive quinone intermediates that subsequently cross-link protein nucleophiles
via multiple 1,4-Michael-type additions. Similar alkylation of protein by protein-tyrosine
kinase inhibitors, such as herbimycin A, has been invoked. See: Cell protein
cross-linking by erbstatin and related compounds by Caroline Stanwell,
Bin Ye, Stuart H Yuspa and Terrence R Burke Jr. in Biochemical Pharmacology
1996, 52 (3), 475-480.
A service of the National Cancer Institute

subset: commoncrawl


text:
Blank 1
Improving Efficiency With Interminable Conference CallsIn observance of the Labor Day holiday, the editors of Insurance & Technology will be taking the day off on Monday, Sept. 5. We'll resume publication of I&T Daily on Tuesday, Sept. 6. For your amusement, here's a bit of Friday humor, appropriate to the theme of the holiday, touching on the less-than-joyful aspect of our work lives.
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EPPING — What a wonderful time the children had at the first meeting of the Lego Club on November 10! Thanks to Epping mom, Kate Moulton for starting the group. The next "block party" will be on Sat., December 8, from 10:30-11:30 a.m. and then hopes to meet twice a month beginning in January.
The Friends of the Library are sponsoring their annual silent auction in the main level of the library. Patrons use their library account number to bid on gift certificates from local restaurants and lovely handmade gift baskets. Stop by to view and bid on the items and support the Friends. The drawing will be held on Tues., December 11 at a 7:00 p.m. combined meeting of the book groups and the Friends' holiday cookie swap.
The holidays are upon us and the annual "Magic of Christmas" pajama night will be on Fri., December 14. Starting at 6:30 p.m. kids from 2-8 and their families will celebrate the season with crafts, a festive scavenger hunt and Christmas stories by the tree. Guests are invited to bring a favorite holiday treat to share for the snack table to go along with cocoa, cookies and egg nog.
On Sat., December 22 the library will host a special showing of "The Polar Express" at 11:00 a.m. in the children's room. Children must be accompanied by a responsible big person, and may bring a picnic lunch or a snack to share. The library will provide popcorn and bottled water during this new Christmas classic. Watch the library desks and website for a listing of movies being selected for the vacation week movie series, which will run a children's new release on Wed., Thurs. and Fri. of vacation.
Epping's public library is open Mon.-Fri., from 10:00 a.m. to 8:00 p.m. and Sat., 10:00 a.m. to 2:00 p.m. The library will be closing at 2:00 p.m. on Mon., December 24 and Mon., December 31, and be closed on the Tues., December 25 and Tues., January 1. Enjoy the holidays! For more information, call 734-4587 to reach the main desk, 679-5944 for the children's room, or visit www.eppinglibrary.com.


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Routes Sorted
L to R R to L Alpha
Swiss Cheese was the first bolted line one encountered upon entering the canyon proper (before all of the new bolting). Generally speaking there is a pile of cheater stones at the bottom of the route to assist in the direct variation. The stones are there to overcome the overhang, and avoid tumbling into the hollow/cave below. These cheater stones may be considered a sage tactic by some, and in my humble opinion are more sketchy than pulling the move outright. The actual route starts in the corner (getting up the corner and over to the first bolt is the crux) to the right and traverses into the route. The route proper is slightly off angle and follows a line of great patina holds, that seem to define the phrase "great patina holds" - up the beautiful sandstone wall. This is a great route, especially for someone learning to lead.
4 Bolts to a pair of chains - a stick clip might be useful for the first bolt.


text:
Security Issues with IBM DB2 Database
iDenfense security service reports six vulnerabilities in IBM's DB2 database.
The issues were discovered in versions 8 and 9 of IBM's DB2 database solution. The CVE IDs CVE-2007-4276, CVE-2007-4275, CVE-2007-4273, CVE-2007-4272, CVE-2007-4271 and CVE-2007-4270 have been assigned. The first vulnerability triggers a buffer overflow in the database when an attacker specifies a specially crafted string via certain environment variable (issue 4276). The attacker could gain the ability to execute arbitrary code. The second vulnerability (4275) gives attackers the ability to load or run their own binaries when entering a search key.
Another critical error (issue 4273) is cased by vulnerable setuid binaries in DB2. An attacker creating specially crafted symbolic links on the system could trick the system into following the links when creating new directories thus opening the system up to the attacker who would possess full write privileges for the new directories.
The remaining vulnerabilities are all related to faulty file and directory management and could allow attackers to gain root privileges. Details on all vulnerabilities are available from idefense. IBM has responded by releasing fixes to patch the vulnerabilities in both versions of the database (Fix for Version 8, Fix for Version 8).
Issue 166/2014
Buy this issue as a PDF
Tag Cloud
Knoppix 7.4 Released
Klaus Knopper announces the latest version of his iconic Live Linux system.
PHP Attack Puts WordPress and Drupal at Risk
All websites that use these popular CMS tools could be vulnerable to denial of service attacks if users don't install the updates.
Heartbleed Bleeds On
According to a report, many potential victims of the Heartbleed attack have patched their systems, but few have cleaned up the crime scene to protect themselves from the effects of a previous intrusion.
Drone Brain Goes Open Source
DARPA and NICTA release the code for the ultra-secure microkernel system used in aerial drones.
Password Management Services Vulnerable to Attack
Should you trust an online service to store your online passwords?
New Raspberry Pi Adds Two USB Ports
New B+ board lets you build cool things without the complication of a powered USB hub.
Microsoft Grabs No-IP.com Domains
Redmond rushes in to root out alleged malware haven.
Firefox Steps into 3D
New initiative will bring futuristic virtual reality effects to the web surfing experience.
New Trojan Targets Online Banking
Dyreza malware launches a man-in-the-middle attack that compromises SSL.
HP Rolls Out Massive Cloud Network
New cloud combines worldwide access with local attention to data security.


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What wine goes with Hamburgers?
If you need a wine to pair with Hamburgers, you could try a Blaufränkisch to go with it.
(blouw-FRAHN-keesh): A fruity red wine with wild strawberries and acidity.
Another wine pairing for Hamburgers
You may also enjoy these other types of wine with Hamburgers:
Bordeaux Blend (Red)
(bohr-DOH): A robust, full-bodied red wine blend with black currant, spice, and cedar.
Cabernet Sauvignon
(ka-behr-NAY soh-vihn-YOHN): A rich red wine with red fruit mixed with spice.
Check out other types of wine with different types of foods
Or, you can browse other ideas for food pairing with Blaufränkisch
Food and Wine Pairing
If you'd like find what wine goes with what food, you can use the Hello Vino tool on this page, or view our large list of food and wine pairing suggestions.
Search for a Wine Pairing:
For example, search wine with turkey or gouda wine pairing.


text:
The working way of an insurance intermediary is characterized by a great diversity of professional and legal challenges. An insurance intermediary must have a profound knowledge of the market of insurance products and an outstanding expertise in the settlement of claims, but it is the European Directive on insurance mediation which enhances considerably the requirements on the quality of his consultancy services.
The law firm Kanzlei am Ärztehaus will be glad to assist you during the phase of consultancy by the customers acquisition as well as in supporting them during the phase of development of your agent-customer relationship. Moreover we will be glad to provide extensive legal advice in the drafting of contracts with insurance companies and other employees.
Our consultancy services include the following areas:


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Area emergency crews had a busy Friday afternoon.
At around 3 p.m., firefighters from Spokane County Fire District No. 4 (Stations 41, 42, 45 and 49) and the Department of Natural Resources were called out to an acre-size brush and timber fire on Dalton Road near Owens Road.
The fire closed a portion of Dalton Road, which forced traffic, including school buses, to find alternative routes through the area.
While fire crews were getting the Dalton Road fire under control, DNR was called to another brush fire in a remote area near Horseshoe Lake.


text:
Jays get 1st Big East home win
OMAHA, Neb. -- Michelle Sicner had a triple-double as the Creighton Volleyball team won its first BIG EAST home match with a 3-1 come-from-behind victory over DePaul on Friday night.
Scores of the match in favor of Creighton were 25-27, 25-18, 25-14, 25-16.
Creighton improved to 11-4 (2-1 BIG EAST), while DePaul fell to 14-3 (1-3 BIG EAST).
Sicner did a little bit of everything to collect her second career triple-double. The junior from Omaha had 39 assists, 12 digs and a career-best 12 kills. Her .579 hitting in 33 swings was easily a season-best, as well.
Kelli Browning topped CU with match-bests of 14 kills and eight blocks, while freshman Jess Bird came on late to finish with 12 kills, seven digs and five blocks. Creighton finished with 58 kills, 58 digs and 13 blocks while adding a season-high 11 aces. CU hit .233 for the match, including a .344 mark in the final set.
DePaul was led by 12 kills ffrom Abbie Fleener, while Vesela Zapryanova had 10 kills. Allyson Rooks topped the Blue Demons with 18 digs, while Colleen Smith had 28 assists and 13 digs while splitting time at setter with Laura Witt. DePaul had 41 kills, three aces, 53 digs and 10 blocks.
Creighton led most of the first set, but DePaul rallied late to earn the early lead in the match with a 27-25 victory. The Blue Demons saved a pair of set points before a 3-0 run to close it out. Zapryanova had a kill and an ace to set up a DePaul double-block to ice the victory. Fleener had five kills and Natalie Rizzo three blocks to pace DPU in the first set, while CU was led by four kills and two blocks.
Creighton led for all but one point of the second set. Bird and Lizzy Stivers both had aces in seperate 4-0 serving runs that helped the Jays to a 9-3 lead, and CU led by three or more the rest of the way. Browning had six kills in seven swings during the set, as CU hit .324.
Creighton controlled the third set after DePaul quickly struck to a 3-0 lead. Melanie Jereb made a rare appearance off the bench to serve up a 6-0 run as CU reclaimed a 10-7 lead. Browning had a hand in two blocks as CU gained momentum, and Sicner ended any doubt of a comeback by unleashing a seven-point scoring run to make it 23-13. Creighton limited DePaul to four kills in the set, as the Bluejay block had six stuffs and held the Blue Demons to -.172 hitting. Sicner had seven assists, five digs, three kills and two blocks in the third set as CU took a 2-1 lead after a 25-14 win.
Another extended serving run from Jereb in the fourth set helped close out the match. Trailing 6-4, Jereb served up a 7-0 run that featured two kills from Sicner and two kills and two blocks by Bird. CU would steadily pull away in the 25-16 victory. Sicner and Bird both had four kills in the last set.
Creighton returns to action on Sunday with a 1 pm match against league-leading Marquette (11-4, 3-0 BIG EAST). Creighton was picked to win the BIG EAST, with Marquette second, in a preseason poll of league coaches. It will be the team's first meeting since CU's 3-0 NCAA Tournament victory last November.
© 2014 Rural Radio Network. All rights reserved. Republishing, rebroadcasting, rewriting, redistributing prohibited. Copyright Information


text:
County Commission President Bruce Hamrick is organizing the first ceremony. It will begin at the county courthouse at 10:30 a.m. on Saturday.
On Monday, there will be two ceremonies, one in Sumiton and the other at Walker Memory Gardens in Jasper.
The Sumiton-Area Veteran's Board will host a ceremony, starting at 10 a.m. on Monday at the Sumiton Community Center. Sonny Richardson, former Veteran's Administration representative for the Jasper area, will be the featured speaker.
"He's helped a lot of the guys that were in the service around here," organizer Bill Fowler said
They will also honor Lecil Goodwin, a local veteran who passed away a few months ago, and his family, along with the traditional 21-gun salute and playing of Taps. There will be light refreshments served.
The Knights of Columbus will host their fifth annual ceremony at Walker Memory Gardens beginning at 10 a.m. David Hester has organized the event, which will feature Stephen Koach as the keynote speaker and will honor Richard Gilmore III. Gilmore was the first Walker County citizen killed in Iraq. Gilmore's family will be honored guests at the event and will place a wreath at the veteran's memorial during the ceremony.
"Memorial Day is a holiday we take for granted sometimes," Hester said. "This has been a real labor of love for me and a way to start off that morning remembering what it is all about."
Fowler echoed those sentiments as well, "It's not just a day of barbecuing but a day to remember those who gave their lives. As a nation, we still have a certain amount of freedom because of those people who were willing to sacrifice."


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The yellow dress. The green bra & panty. Petra's spectacular for needs no enhancment, but the colors set it all off very well.
Petra Verkaik, a 22-year-old native Californian, celebrated the signing of her Playmate contract in an unusual fashion: by running herself over with her own van. The venerable '76 Volkswagen has a habit of not starting, so Petra's accustomed to climbing under the chassis, armed with a screwdriver, to get things going. This time, in her excitement about becoming a Playmate, she neglected to check whether or not the transmission was in gear. When the motor turned over, the van lurched onto her chest and perched there for about 30 seconds. "A very long thirty seconds," she says. "I thought I was going to die." With a mighty effort -- "I'm not Hercules or anything, but it's a light car" - Petra managed to free herself, sort of. "I pushed it up and slid under it. Then it landed on my hair, pinning me." Fortunately, the episode took place in the parking lot next to Playboy's West Coast offices, and rescue was soon at hand. Cassie Gould, a Playboy publicist, was the first to happen by and see two legs sticking out from beneath the dilapidated van. Her call for help was answered by two security who quickly got the van off the Playmate; paramedics and sheriff's officers arrived seconds later. At the hospital, Petra was X-rayed and got the good news that she could go home immediately. The bad news was that now that Petra was obviously out of danger, everybody was cracking jokes about the accident. When a Playmate, particularly a well-endowed Playmate, is saved from serious injury by her breasts, people smile. It's not unlike the story of a preacher's being saved from a stray bullet by his Bible. And Petra is by nature a rather shy person. "God, I was so embarrassed," she recalls. Still, when she heard that West Coast Photo Editor Marilyn Grabowski had dubbed her the "the retread Playmate," Petra good-naturedly responded, "Well, I did have tread marks on my shirt. What else can I do but laugh?" Petra and her misbehaving van go way back. "My mom bought it new, and we used it to camp at the Grand Canyon and everywhere." Last year, her mother gave Petra the van. Since then, its trips have most often been to the mechanic. Still, it has provided reliable-enough transportation to get Petra to modeling assignments (she recently did some promotional work for Pepsi). She currently shares a house near L.A. with three others, including her boyfriend, with whom she pots fantasy travel plans (first stop: Bali, her mother's birthplace; her father comes from Holland). Her next move, however, may be to try out for a spot in Playboy's Girls of Rock & Roll review, currently in Las Vegas and Lake Tahoe. "Playboy has helped me a lot," says Petra. "It has given me self-confidence. Now I love meeting people." There's another plus: With her Playmate earnings, she'll be able to buy a new car. "Something light," she says, smiling. "Like a Honda CRX."
PlaymatesPlaymatesPlaymate Xtra - Petra Verkaik
PlaymatesPlaymatesPlaymate of the Month January 1983 - Lonny Chin
PlaymatesPlaymatesPlaymate Test Shots - Carrie Stevens
PlaymatesPlaymatesPlaymate Xtra - Petra Verkaik 05
6 comments
Petra is my favorite Playmate. Glorious Glorious Petra!!!
The most impressive breasts can be seen from the BACK :) PHOTO #2
I was completely rendered STUNNED by this STACKED beauty. Thank you Petra and PLAYBOY!
When I received my monthly copy in the mail and saw Petra in the centerfold I immediately went to my bedroom. With my heart racing and panting all I needed was the bottle of baby oil and a box of kleenex. WOW! Thank you Petra and Playboy.
In my opinion Petra is the sexiest and most BEAUTIFULL playmate of all time, BAR NONE
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Christal Young checked out sporty fashions worn by staffers at Self Magazine.
She was wearing a jacket and tank by the Gap. The tank cost $10 and the jacket $60.
Her skirt cost $129 at Zara and her shoes were $59 from Enzo Angiolini.
Varsity jacket by True Religion, $497
Limited edition Dunks by Nike, $250
Shoes by Lulu's, $42
Jeweled top by J.Crew, about $120
Nike tech fleece hoodie cape, $110


text:
Courses for Fall 2010
Medical Humanities: Critical Perspectives on Illness, Healing and Culture
Bianca Dahl, Postdoctoral Fellow in International Humanities
Medicine is arguably the most humanistic of the hard sciences, one that strives to ensure the basic dignity of individuals. In our increasingly globalized world, access to medical care is recognized as a fundamental human right. However, there continues to be considerable debate over the "best" ways to provide medical services to economically and culturally diverse communities across the globe, given the complex ways that people prioritize and perpetuate their health. Drawing on a range of disciplines, this seminar explores the multifaceted relationships between biomedicine and cultural understandings of illness, both in the US and worldwide. Instructor permission required.
Ethics and the Humanities
Sheila Bonde, Faculty Fellow
This seminar will engage with ethical issues in a broad range of humanities disciplines. We will survey historical and thematic perspectives on ethics and will consider the ethical implications of authorship and possession of texts and objects; translation as an ethical problem; data and open access; the perspective of the human subject; public humanities, public intellectuals and community-based research; and ethical issues in popular culture.
Medicine and Colonialism in the Atlantic World: A View from the South
Adrián López Denis, Postdoctoral Fellow in International Humanities
This seminar examines the role of disease, medicine, and health in the history of the Atlantic World. Our analysis will be centered on events that took place in Latin America, the Caribbean, and Sub-Saharan Africa, during the era of European colonial expansion (1490-1940). In these four and a half centuries, the West became the dominant force in global geopolitics and Western medicine emerged as the hegemonic form of healing worldwide. This seminar explores the complex relationship between these two historical developments.
And What About the Human?
Barrymore A. Bogues
This course will think about the question posed by radical anti-colonial thought: and what about the Human? Through the writings of Foucault, Arendt, Heidegger, Fanon, Wynter and Cesaire, as well as the novels of Lamming and Vera, we will examine the meaning of the "death of Man" in contemporary critical thought and theory, and the ways in which western anti-humanism thought claims to replace the figure of the human with discourse and language, while also contrasting the ways in which radical anti-colonial thought has constructed the figure of the human.
Spring 2011
Pragmatic Medical Humanities
Jay Baruch, MD, Faculty Fellow
The question, "What is medical humanities?" has flummoxed the very experts who ardently argue for its importance to medical education and the professional and personal growth of health care providers. Individual persons harbor different meanings for the term, invest it with different values and goals.
The interdisciplinary nature of medical humanities, engaging in conversations with persons who possess different expertise, different knowledge and different approaches to knowing, provides opportunities for examination and insight unavailable elsewhere.
During this seminar, students will investigate alternative meanings, interpretations and purposes embedded in the term "medical humanities." They will develop their own personal relationship to this term, this field of study, and its utility as a tool for understanding and responding to the profound experiences of clinical medicine, illness and health.
Concepts of Space and Time in Media Discourse
Gertrud Koch, Visiting Faculty in the Humanities
This course aims to bind different discourses about space and time from different disciplines together, including philosophy, art theory and cinema studies. It centers on questions of how space and time are conceptually, socially and aesthetically constructed via and thru different media. In Benjamin for example the urban mass functions as medium through which the city develops into a specific public space and film functions as medium through which the mass constitutes itself. Technical and aesthetic media are involved in modern subject formations both on an individual and on a social level.
Perspectival constructions of space were always in the center of analysis when it came to cultural representations of the subject. The main focus of the course will be in reconstructing the discourses on perspectivism (Nietzsche), pictorial perspective (Renaissance perspective) and cinematic appropriations of both. The other organization of perspectives is the temporal one. Past, present, future are at stake for the organization of narratives – both in terms of historical and fictional regards. During the course we will look on concepts of narrative and temporal perspectives in the context of general theories of times as well as in the context of specific media as photography and film.
To see the humanities related course catalog for 2010-11, click here. These are courses taught by Cogut Center Fellows for other departments.
To see the HMAN courses we offered in 2009-10, click here.


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• What is Canine Influenza? A strain of the influenza A virus known as H3N8, a highly contagious "flu" that is able to cause respiratory illness in dogs. Canine influenza only affects dogs. Humans are not at risk of contracting it.
• How serious is canine influenza? It can be very serious! Not only is it highly contagious, but virtually all dogs are at risk. Cases have been reported in 38 states, including Texas.
• What are the signs of canine influenza? The most common sign is a persistent cough, which makes it very hard to initially diagnose (due to its similarity to what is commonly referred to as kennel cough). In mild cases, signs can include a low-grade fever, nasal discharge, lack of energy, loss of appetite, and a cough that can last for up to a month. In more severe cases, a high grade fever and pneumonia can develop.
• Is your dog at risk? Did it come from a shelter, rescue center, breeder, or pet store? Do you board your pet at a kennel or go to doggie daycare? Attend group dog training? Visit a grooming facility or dog parks? Enter or attend dog events? Come into contact with other dogs in the waiting room during visits to the vet? If so, your pet may be at risk.
• How is it spread? The same way as human flu: direct contact (touching noses, sharing water bowls & toys), through the air (sneezing & coughing), and via contaminated surfaces.
• How to protect your dog against canine influenza: There is a vaccine to help protect your dog. The initial vaccine requires 2 doses, 2-4 weeks apart, followed by annual revaccination. If your dog is currently vaccinated for kennel cough (bordetella), it is a likely candidate for the canine influenza vaccine.
• The Houston Humane Society offers the canine influenza vaccine at our low cost Wellness Center. And we feel it is so important that we also vaccinate all of our adoptables upon arrival at the shelter. For more information about canine influenza, please visit the Houston Humane Society's Animal Wellness Center.
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|Excellent - 12 reviews
Overall Rating - Excellent - 12 reviews
|Okay - 29 reviews
The Magnuson Hotel and Suites Nisswa places you minutes from Championship Golf and Outdoor Activities. Just 12 miles north of Brainerd on Highway 371, our Nisswa hotel near Paul Bunyan Trail puts you within minutes of abundant water activity, golf courses, shopping, restaurants and popular attractions like Brainerd International Speedway. Hike, bike or snowm...
Overall Rating - Okay - 29 reviews
Good 8.0
It was clean- the beds were comfortable. We didn't need a fancy room.
It was advertised that there was wifi in the rooms--there was NOT. That made me very unhappy.
Excellent 10.0
It's older but clean. Smells clean, feels clean. Very nice accommodations for what you pay.
They were having issues with the A/C in the pool area, it was very warm in there.I would recommend staying here. Not a 5 star by any means but they don't pretend they are either. Clean hotel, fair priced, continental breakfast.
|no reviews
|Good - 40 reviews
Whitefish Lodge and Suites is located in Crosslake. Make yourself at home in one of the 54 air-conditioned rooms featuring flat-screen televisions. Your room comes with a pillowtop bed. Complimentary wired and wireless Internet access keeps you connected, and cable programming provides entertainment. Bathrooms have shower/tub combinations and hair dryers. Ta...
Overall Rating - Good - 40 reviews
|Okay - 12 reviews
Located in Brainerd, Americas Best Value Inn is close to Buffalo Hills Park and Northland Arboretum. This hotel is within the region of Paul Bunyan Land. Make yourself at home in one of the 34 guestrooms featuring refrigerators and microwaves. Complimentary wireless Internet access is available to keep you connected. Featured amenities include complimentary...
Overall Rating - Okay - 12 reviews
Poor 1.0
That I was able to open the window for fresh air.
Mildewy smell, dirt in corners, no remote for the TV, bed made up poorly, if I was unable to open the window it would not have been good for my asthma.Front desk staff out front smoking at one point, front desk unmanned at another point, back door left open and fully accessible (I was slightly concerned at night due to this, but we double locked our door).
Good 8.0
I knew it would be pretty much basic, but this place was very clean and comfortable compared to other basic motels I have stayed. I would certainly stay there again.
The parking lot was full when we arrived late on Friday. There is a sort of overflow lot, but not a lot of room for large vehicles or trailers.It is at the south end of Brainerd, so farther away from Brainerd International Raceway where I was spending the weekend. The staff was very accommodating when we let them know we would be checking in late. The rooms were quite clean without the usual cloying odor of disinfectant. Beds were comfortable. Breakfast was as expected with waffles and cereal choices in addition to donuts and bagels.
|Excellent - 5 reviews
Overall Rating - Excellent - 5 reviews
|Excellent - 16 reviews
Overall Rating - Excellent - 16 reviews
|Okay - 10 reviews
Overall Rating - Okay - 10 reviews
|Good - 46 reviews
This Rodeway Inn hotel is located on the Paul Bunyan Trail. There are 100 miles of snowmobile and biking trails that run from Brainerd to Bemidji that include the towns of Nisswa, Pequot Lake, Jenkins, Pine River, Backus, Hackensack, Walker and Cass Lake. Brainerd International Raceway and Ski Gull are nearby. Hotel features free continental breakfast, free...
Overall Rating - Good - 46 reviews
Okay 5.0
We were given a smoking room so had that smell to deal with. Room gave the appearance of clean but dont' look too close- stained sheets, dirt in the corners etc. Overall fine for one night but I wouldn't want a long stay there.
It was what was to be expected for the star level.
Okay 5.0
It was a safe clean place to spend the night. They did not charge extra for the little 5 lb Chihuahua!
The staff could have been a little more outgoing. Although it was the end of their day.
|no reviews
|Excellent - 8 reviews
Overall Rating - Excellent - 8 reviews
|no reviews
Secluded thirty-five acre B&B three miles from Brainerd. Private bath themed rooms with names such as "three marigolds and one other flower", "starry starry night", and "miss 4th of july" allude to the unique decor in each room. In addition to Inn rooms, you may stay to rear of old fashioned general store with 1930-40's cars and trucks parked beside antique...


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Corporate Equalities Employment Policy
5.1 Other forms of discrimination
The County Council recognises that other forms of discrimination exist which have not been specifically dealt within this policy document (e.g. religion, dress codes, health issues, trade union activity, etc.) and commits itself to the general principle of fairness, justice and equality. It will seek to apply this principle to every area where inequality is identified.
5.2 Consultation
The County Council will consult with representatives of each of the groups outlined who may be subject to discrimination or disadvantage and with trade unions, to ensure that its policies and practice reflect the true needs of the groups.


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Sporting Kansas City
Having met in each of the last two seasons in the MLS Cup Playoffs, the Houston Dynamo and Sporting Kansas City once again renew acquaintances on Sunday evening at BBVA Compass Stadium. The Dynamo return home off a two- game winning road swing, without shutouts in both, after a midweek 4-0 win at D.C. United. Sporting hit the road following a second loss in a three-game homestand, a late 1-0 defeat by Seattle Sounders FC. The Dynamo have knocked higher-seeded Sporting out of the postseason in each of the last two seasons.
Broadcast Info
TV: CSN / Free on MLS Live
Radio: 1560 AM / 850 AM
Starting Lineups
Dynamo: Hall; Sarkodie, Boswell, Taylor, Ashe; Clark, Moffat, Davis (C); Garcia, Bruin, Driver.
Subs: Marscheider, Chabala, Brunner, Camargo, Dixon, Ching, Johnson.
Sporting KC: Nielsen; Jerome, Collin, Opara, Sinovic; Nagamura, Rosell. Joseph; Zusi, Bieler, Peterson.
Subs: Kronberg, Gardner, Myers, Olum, Feilhaber, Kamara, Sapong.
Get up-to-the minute stats throughout the match
In this week's episode of Dynamo Weekly, Sebastian Salazar and Glenn Davis break down Sunday's match between the Houston Dynamo and Sporting KC.
To secure your seats for Sunday's match, visit HoustonDynamo.com/Tickets or call (713) 276-GOAL.
Take a look at some of the key talking points ahead of this week's match against Eastern Conference rival Sporting Kansas City.
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YUMA – (KSWT News 13) - The City of Yuma will hold primary and general elections in 2013. Up for grabs are five seats: city mayor, three city council seats and municipal judge.
Al Krieger is currently the city's mayor. The three city council seats up for election are the ones held by Paul Johnson, Jerry Stuart and Bobbi Lewis.
"We don't know who is running yet or not. We've only had the announcement that candidate packs are available for pickup for a couple of days now," says Dave Nash, Public Information Officer for the City of Yuma.
Nomination packets for those wanting to run are available from the City Clerk's office, located on the first floor of Yuma City Hall on Third Street between First and Madison Avenues.
"The best thing to do is to go to the City Clerk's office because they'll give you a 13-page manual and then a package for petitions. The manual is also available online," explains Nash.
Nash recommends people interested in running pick up a packet at the city clerk's office if they have any questions about the process of becoming a candidate. All five positions are for four-year terms, beginning on January 1, 2014.
The primary election will take place on August 27th. The general election will be held on November 5th.
The first day for candidates to file nomination papers and other nomination forms is April 29th. The deadline to file nomination paperwork is May 29th (5pm). That's when we'll know, officially, who's in the running.
In an attempt to serve an out of state felony warrant in Somerton, the U.S. Marshal's came up empty handed Thursday afternoon. Officials tell News 13 the suspect they were looking for was Caleb Kinsey.


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To does not work and with is not very good either. The best preposition here is into. Incorporate comes from the Latin corpus, corpore meaning body. It means to merge something into something else.
The example you gave is one of the most literal I can think of. Your toothbrush became part of your arm.
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Style Map
Daily Dispatches From The Global Scene
"To live life and to experience its many ups and downs is how we discover who we are," says Applewaite. "Similarly, to know your aesthetic in design is to experience the many nuances of the process and to react and critique based on your individual choices."
Kaye Applewaite is a twenty-four-year-old Barbadian designer. As a child, she had a creative spirit, but growing up on a small island where there were very limited opportunities for design, her initial career choice was medicine. Having been accepted into medical school, she instead decided to take a fashion-design course at a local community college. After graduating from the school as valedictorian, she worked in the local industry for a year, collaborating with other designers and building a small clientele. In order to reach her full potential, she applied to Parsons The New School for Design. During her course of study, she interned for Catherine Malandrino and Yigal Azrouël, and was also awarded the Coach Scholarship for her work in accessory design. She developed a strong focus on experimentation, which led to her thesis, The Arc of Self, a collection driven by her search for identity. It is an individual critique of the process of design, from an initial idea to the final garment. What began as the deconstruction of a hoodie resulted in a five-piece collection that is a blueprint to the thought process.
Daily Dispatches From The Global Scene


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My first attempt at photographing the milky way. Taken last June along Antelope Flats in GTNP. Afraid I do not have a fast enough wide angle lens to really get some detail in the sky. I do have the nifty fifty and might give it a try this summer. Just have to walk backwards a bit. Need more practice at this!
Canon 1D Mark IV
Canon 17-40mm L
24 seconds
6400 iso
580ex flash dialed way down (can not remember) during exposure.
Lovely shot. Well done.


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Beach Cross event cancelled due to storms (From Dorset Echo)
When news happens get involved. Send your pictures, views and video to us by text and email
Beach Cross event cancelled due to storms
5:32pm Friday 14th February 2014 in News
NEXT weekend's quad bike extravaganza on Weymouth beach has been cancelled because of the bad weather.
Dickies Quad Beach Cross had hoped to build on the great success of the first event held in February last year.
This all-action motoring event promised to attract big crowds and generate a real boost to the trade throughout the area during the traditional off-peak season.
However, a spokesman said they had been forced to cancel over concern for the safety of competitors, trade exhibitors and spectators, with potential wind damage to the temporary structures required for the event including trade stands, security fencing and signage.
He said: "We have duty of care to the public and want them to enjoy the fantastic spectacle of our sport – but more importantly be safe.
"The storms that Weymouth has already endured has caused significant damage to the beach and moved high volumes of sand to one end of the beach, this would also cause severe restrictions with the course build.
"We have been able to confirm a rearranged date with the council and the event will now run on November 15 and 16.
"We sincerely apologise for any inconvenience caused and on a positive note we are looking forward to November."
Comments (1)
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8:03pm Fri 14 Feb 14
jmc1 says...
Wind rain and snow will be back by then
Comments are closed on this article.


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The Foreign Ministers of the NATO member states are assembling in Brussels. They are now waiting for the NATO secretary general Anders Fogh Rasmussen to join them. At 17:30 Tbilisi time, the representatives of the ISAF participant nations will assemble in Brussels and conclude their talks with a meeting on Afghanistan with ISAF partners and the Deputy Afghan Foreign Minister.The NATO Secretary General will sum up the meetings at the press conference this evening.
A few days before the summit in Wales, NATO Secretary General Anders Fogh Rasmussen mentioned Georgia when briefing about the Alliance plans for the future. He reiterated that Georgia would receive a new package at the Summit in Wales, which would bring the country closer to the Alliance.
`Georgia was punished for its free choice", - the President of Georgia announced at the international forum of leaders - The forum entitled `Building a Modern State in 21st Century - Georgia`. The forum was opened by President Margvelashvili.
The Georgian Prime Minister will chair the delegation of Georgia at the UN 69th session, instead of President Margvelashvili - deputy foreign minister of Georgia, Davit Zalkaliani stated at today`s briefing.
The autumn session of the parliament will be opened tomorrow in Tbilisi. The reconstructed building of the parliament is ready to receive the lawmakers.
Comedy talk-show with famous guests, headlines and others
Hilarious sketches with amazing performances of your favourite actors!
A 29 year-old man was killed in Marneuli town last night. The incident occurred on Gamsakhurdia Street. The killer inflicted a fatal injury with a knife to the man`s breast. The suspect has been identified and he is now wanted by the police. The criminal case has been filed with the charges of premeditated murder.
The politicians have made different assessments of the reports on possible decision of the prosecutor`s office to declare former president Mikheil Saakashvili internationally wanted. Foreign Minister Maia Panjikidze says this process will in no way affect Georgia`s relations with partners and any legal decision taken by the prosecutor`s office...
The fact of the argument that occurred in the Mestia Police Department last night has not been officially confirmed by the Press Service of the Ministry of Internal Affairs today. However, one of the police officers...
Most of the essential parts of the EU Association Agreement with Georgia temporarily enter into force from today. According to the terms and conditions of the Deep and Comprehensive Free Trade Area (DCFTA), all Georgian made products will be freed of the customs fee when exported to EU market...
© 1994-2014 Rustavi 2 Broadcasting Company


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Got home last night and couldn't wait to get to the shop this morning.
After 3+ weeks of being gone I put a little gas in 49-1 and it started on the second crank. Man it sure runs good.
Here's where it turns bad.
I decided to put the shift lever on and move the tractor back and forth. Well when I let out the clutch one heck of a racket comes form (I think)the tranny. Does it in all gears. Sounds like rattling gears.
When I rebuilt the tranny there were no chipped gears and all was in great shape. I did notice that when I put the reverse idler gear in the tranny it made more noise than it did without the idler.
Any thoughts besides I screwed something up


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---- — The North Country Chamber of Commerce has developed, over the years, an excellent recognition of this region's connectivity with Canada.
Under the leadership of President Garry Douglas, the chamber keeps a good eye on developments across the border that may have an impact on our area. The organization has dedicated itself to developing solid relationships with Quebec government and business leaders and has worked hard to entice more Canadian development in the North Country.
The chamber has promoted the idea that this area is "Montreal's U.S. suburb," recognizing the impact that Quebec and its people have here.
So chamber leadership watched with keen interest the recent Quebec elections and, in a recent chamber newsletter, proclaimed it "an important election day for the North Country." They have already reached out to new government leaders there.
Here are some excerpts from Douglas's statement on the elections:
"The Quebec election of the past month has prompted a great deal of outreach and communication on the part of the chamber and its partners, as it saw the defeat of the majority Liberal government led by Premier Jean Charest and the election of a minority Parti Quebecois (PQ) government now led by new Premier Pauline Marois.
"The North Country Chamber of Commerce has enjoyed an active partnership with the Quebec government and its premiers going back to Lucien Bouchard, when we began working on such shared aims as border efficiency and transportation.
"In 2002, this evolved into the Quebec-New York Corridor Coalition, a formal private-public partnership involving the North Country Chamber on behalf of New York business, the Federation of Quebec Chambers on behalf of Quebec business, and the Quebec and New York State governments.
"That year, we enjoyed working with Premier Bernard Landry to plan and conduct a highly successful first Quebec-New York Summit in Plattsburgh, and our relationship with Quebec's leaders has only grown since then. This includes nine years and three summits with our good friend Jean Charest, who has more than once referred to the North Country Chamber as Quebec's best friend in the U.S.
"We have now congratulated Pauline Marois on her selection as Quebec's first woman premier, and we are looking forward to establishing what we have every reason to expect to be the same working relationship we have enjoyed with her predecessors. The importance of the Quebec-New York relationship remains paramount ....
"We look forward to meeting with the new premier and her team in the very near future, building and continuing the friendship we have always enjoyed, smoothly transitioning current discussions around various issues and opportunities, and refreshing the planning process for a fifth Quebec-New York Summit as soon as Quebec is ready."
The chamber's efforts in regard to Quebec are tres bon for the North Country.


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Available Colors/Styles
Detail Pics
Take powder panic to the next level.
If you've ever watched Jake Blauvelt float a massive, tweaked-out spin off some gnarly natural feature, you know what the Ride Berzerker Snowboard is capable of. The stable yet floaty Hybrid All-Mountain profile and poppy flex offer a stompable, shreddable ride for pow-hungry riders with big boots. The wide version of the Berzerker is recommended for riders with
boot size 11 or larger.
The Berzerker also uses Ride's proven Slimewalls sidewall technology―urethane sidewalls that absorb impact to smooth the ride and allow you to ride harder, longer. They're also some of the toughest sidewalls in the industry. Along with Slimewalls, Ride's Carbon Array 3 Laminates add stiffness throughout the board for better board control. All of this technology is built around Ride's Pop Rods Core, which sandwiches Slimewalls urethane material between flat carbon rods for tons of pop without added stiffness. Ride finishes off the Berzerker with its Fusion 4000 Base—the fastest base material known to man.
- Rocker in the nose with micro camber through the tail
- True twin shape
- Cleave Edge reinforced edges
- Slimewalls urethane sidewalls
- Carbon 3 Array stringers
- Pop Rods urehtane-sandwiched carbon core
- Fusion 4000 sintered base


text: Quick View The Biggest Loser Success Secrets: The Wisdom… by Loser Biggest January 23, 2013 | Trade Paperback In Stock from $6.64 Millions of viewers have watched the contestants on The Biggest Loser , NBC''s hit show, radically transform their bodies and their lives. In turn, many of those inspired fans have shed countless pounds on their own by following The Biggest Loser weight-loss program. But as anyone… See Details $6.99 / $6.64 lowest price*, or used from $5.00was $23.95


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As digital advertising spend continues to chip away at traditional media spend, many local media organizations are looking for new sources of revenue and ways to serve their clients. Social and mobile solutions provide these organizations with a variety of new opportunities to expand their product line and help SMBs attract new customers.
We are excited to partner with Borrell Associates and the Local Media Association for the upcoming "Social + Mobile: Show Me the Money!" conference, taking place August 20th-21st in Chicago.
At this year's event, we'll hear from the heaviest hitters in social and mobile, digital agencies and clients on the best ways to make money from these platforms. The event also promises superb networking by bringing together professionals from three leading local media organizations, along with a variety of receptions and other ways to get to know one another.
Notable speakers will include:
- Ted Zagat, Ads, Facebook
- Lutz Finger, Director Data Science & Data Engineering, LinkedIn
- Joel Meek, Head of Partner Online Sales & Operations, Pinterest
- PJ MacGregor, Brand Development Lead, Instagram
- Greg Stuart, Global CEO, Mobile Marketing Association
- Luke Edson, VP of National Markets, YP
- And many more…
So if you work for a local media organization and you want to learn what your colleagues are doing to grow digital revenues, SoMoConf is for you. You're bound to make some new connections and leave with fresh ideas on how to drive sales. Click here to learn more.


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About 250 West Jasper students took part in the Run for the Planet, an initiative of National Geographic Kids in cooperation with Guinness World Records that saw people around the world attempting to set a new world record for the most people to run or walk 100 meters in 24 hours.
"We're trying to help set the record of how many individuals can run this, (and) we're doing this at a lot of schools in the state," said Nicole Barnes, a coordinator at Institute for America's Health.
The school came to participate in the run by way of the IAH's (Institute for America's Health) Wellness, Academics and You program.
"West Jasper is a WAY model school, and they were asked by representatives from this program to participate," said Rita Pilling, principal at West Jasper Elementary School. "With National Geographic and the Guinness Book of World Records, they're trying to get enough meters run by the children in the WAY program to circle the globe."
Pilling said the students' smiles and laughter displayed confirmed the fun they were having. "Good physical activity is so important for good health."
"Children want to be active, and love for an adult to help them be active," she said.
The WAY program, including events such as Friday's run, allows students to stay active while learning.
"This program helps children reconnect physical activity and academics, knowing that physical activity only improves our academics," Barbara Woodley, the WJS Physical Education teacher said. "I back it up in P.E. with nutrition facts and make sure we're active at least 30 minutes a day here at school. It's teaching the whole child, being well, being academically sound and being happy, because children love to play."


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Displaying 70 - 81 of 81 item(s) found.
Tahki Yarns Mesa
Wool yarn makes some of the best accessories anyone can ever ask for, and the beautiful colors of this collection mixed with the fact that its 100% wool make it the perfect choice for all your...
Tahki Yarns Mimosa
Pick up this silky, smooth yarn that is perfect for creating accessories and making fun little toys for wee ones. Ranging in colors from black and blue to magenta and taupe, youll be able to find a...
Tahki Yarns Ripple
This thick-and-thin cotton yarn has enough texture to make simple stockinette special. Its supple drape and subtle sheen make it eminently wearable and its ample yardage gives the knitter both value...
Tahki Yarns Souffle
Whip yourself up something stunningly sweet and sumptuous with this decadent new yarn collection from Tahki Yarns. The angora and wool fibers will keep you warm and cozy while the durable viscose...
Tahki Yarns Zona
A durable yarn collection with warmth and texture so you can stitch up cozy winter wear! Ideal for everything from mittens and hats to sweaters and wraps, youre sure to stay warm and stylish all...
Universal Yarn Classic Worsted LP
The striping of the colors in this yarn makes it an excellent choice for any project you would like to have an evenly-striped lookvertically or horizontally.
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Universal Yarn Deluxe Worsted Superwash
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Universal Yarn Wisdom Yarns Poems
Universal Yarn Wisdom Yarns Poems is 100% wool and features artistic colors that variegate beautifully. It's perfect for projects that just beg to be felted.
Universal Yarn Wisdom Yarns Poems Silk
The beautiful tonal shifts of our classic Poems wool roving yarn are accented by the added sheen of silk. A blend of 75% wool with 25% silk gives an extra snap to the color of everything you make...


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Workforce Investment Streamlined Performance Reporting
|Workforce Investment Streamlined Performance Reporting (OMB 1205-0469)
March 16, 2009
"WISPR (Workforce Investment Streamlined Performance Reporting) System is Suspended for PY 2009." WISPR implementation has been suspended for Program Year (PY) 2009 because of the challenge posed by the significant role the workforce investment system will play in the President's economic recovery plan. ETA's top priority will be working with our partners and stakeholders to meet the information and reporting needs associated with implementation of the American Recovery and Reinvestment Act (ARRA).
October 2, 2008:
The Workforce Investment Streamlined Performance Reporting (WISPR) documents (Forms 9131, 9132 and 9133) have been approved by OMB (1205-0469) for a potential implementation date of July 1, 2009. This approval marks the beginning of several changes to workforce reporting. These forms will be for use by all grantees administering Wagner-Peyser, Veterans Employment and Training Service, Workforce Investment Act Title IB, National Emergency Grants, and Trade Adjustment Assistance programs funded by the United States Department of Labor (USDOL). The primary purpose of this new reporting system is to:
|WISPR Forms and Handbook:


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1 Bedroom Downtown Seattle Modern Oasis in Seattle
- bedrooms 1
- baths 1
- sleeps 4
- pool no
- hot tub no
- pets allowed no
- type Condo
- community Belltown
rates (USD)
/ night
$ 1,000 - $ 1,200 / week
$ 3,600 - $ 4,300 / month
vacation rental description
Thanks for taking a look at our condo! For more pictures, up to the second availability, quotes, and the ability to book online please visit our website SeattleOasisVacations<.>Com
Welcome to The Urban Oasis, your home away from home in our Downtown Seattle Condo located in the lively Belltown Neighborhood. Professionally designed, this Brand New condo building and this unit features a small balcony, granite and stainless finishes, and all that you will need to cook with while you are staying in our place!
You'll be walking distance to nearly all that Seattle has to offer!
2 Block to Starbucks
5 Blocks to Waterfront shops, walking and bike trails
5 Blocks to the Pike Place Market
6 Blocks to Victoria Clipper
6 Blocks to Space Needle, Experience Music Project, Pacific Science Center, Key Arena, and the rest of Seattle Center
7 Blocks to Olympic Sculpture Park
1/2 Mile to the Seattle Aquarium
1/2 Mile to Westlake Center (Monorail and Light Rail to Airport)
.6 Mile to Seattle Art Museum
.6 Mile to Paramont Theater
.6 Mile to Washington State Convention and Trade Center
.7 Mile to 5th Ave Theater
1 Mile to the Underground Tour and Pioneer Square
1.25 Miles to Qwest Field
1.5 Miles to Safeco Field
Some of the best Restaurants in every direction, including some just outside the front door! Due to this supreme location, as well as Cab and Train service between Downtown Seattle, and the Airport, who needs to rent a car?
During your stay enjoy:
*Designer Kitchen which includes all you need to whip up a fantastic meal
*Luxurious bathrobes for use during your stay
*Plush Mattresses with 600 count sheets
*2 Flat Panel HDTV's
*Secure Parking Garage for use during your stay
*Free Wi-Fi
*Have some of the finest dining establishments just footsteps away from your front door
This condo sets its self apart as it has an ideal location to visit the main attractions in the city with being in the middle of the downtown scene. It is also a modern building built finished in the fall of 2008 versus many of the older buildings built in the 80s or even 50s, and you'll notice the difference in the accommodations. With our unit we offer free and hassel free parking in the garage! Why search for parking or pay for it when you don't have too?
Less than a mile from the Convention Center, and you can cross the street to take a free bus anywhere within the downtown free ride zone!
We try our hardest to make your stay the best it possibly can. And if there is anything we can do to make your stay more comfortable next time...Just let us know! And please enjoy the gift basket in your bedroom with a few things that will make your stay enjoyable. Remember this is a VRBO, not a Hotel so you won't be charged!
As one of our recent guests said in our guest book:
"This is our 40th trip to Seattle, and this is our favoirte place we stayed by far! We look forward to coming back!" Barbara Kiel
If the dates you are looking for are not available, please give us a call or inquire anyway, as we have other units that may be available in this building or a neighboring one.
vacation rental location
property availability
- dates with deals
- unavailable dates
Last modified on 09-2-2014 at 7:31 AM.
email owner view full calendar
Darik Eaton 206-456-5251
condo rental amenities
Our building features an amazing rooftop complete with lounge chairs, stainless steel BBQ for your use, a fire pit and an amazing view of Downtown Seattle!
Our lobby features a pool table, wi-fi computer bar, fitness center, lounge area with fireplace, large Flat Screen TV, and a community kitchen open 24 hours a day!
We also are able to offer guests free parking (one car per unit) in the parking garage, a feature that is hard to find in Vacation Rentals and Hotels in Downtown Seattle! Additional Parking spots are available for rent and can be arranged via the management office upon your arrival.
activities and attractions in Seattle Washington
You'll be walking distance to nearly all that Seattle has to offer!
2 Block to Starbucks
5 Blocks to Waterfront shops, walking and bike trails
5 Blocks to the Pike Place Market
6 Blocks to Victoria Clipper
6 Blocks to Space Needle, Experience Music Project, Pacific Science Center, Key Arena, and the rest of Seattle Center
7 Blocks to Olympic Sculpture Park
1/2 Mile to the Seattle Aquarium
.6 Mile to Seattle Art Museum.6 Mile to Paramont Theater
.6 Mile to Washington State Convention and Trade Center
.7 Mile to 5th Ave Theater
1 Mile to the Underground Tour and Pioneer Square
1.25 Miles to Qwest Field
1.5 Miles to Safeco Field
Sound Transit Service is now Available between the Airport and Westlake Center! For more information please visit the Sound Transit <.> org
Sat: 5:18 AM-12:04 AM
Sun:6:17 AM - 11:05 PM
2.50 Adult 2.00 Youth (6-18) Children under 6 Free with paying adult
Frequency: 7.5-15 Minutes depending on Day/time of day
Duration: 37 Minutes from SEA-TAC to Westlake Center
If you don't want to walk the 6.5 Blocks (1/2 Mile) to the condo the 2, 4, or 16 (among others just ask a local or a bus driver) bus routes are all available on 3rd avenue just a block and a half from Westlake Center and will drop you off directly in front of our building. This is part of the downtown Free ride zone during commute hours!
vacation rental rates
Dec-Feb ..... $145 Sun-Thurs...165 W/E... $1000/week ... $3600/month
March-May...$165 Sun-Thurs...185 W/E... $1150/week ... $4100/month
June-Sep'... $175 Sun-Thurs...195 W/E... $1200/week ... $4300/month
Oct-Nov.......$160 Sun-Thurs...175 W/E... $1100/week ... $4000/month
All Seasons, 2 Night Min, More on Holiday Weekends
Add $75 Cleaning fee for stays less than 5 Nights; All stays <30 Nights 9.5% Tax
First booking for any given month receives 10% Discount off the nightly rate!
Darik Eaton 206-456-5251
accepted payment methods
Prior to paying a reservation deposit, always verify payment instructions by calling the phone number displayed on this listing page. By contacting the owner directly and paying by an approved method - credit card, paypal, check or bank transfer - your reservation payment will be protected up to $1,000.Learn more in our Security Center
Top things to do in Seattle
- Pike Place Market
- The Underground Tour
- Experience Music Project
- Seattle Art Museum (The SAM)
- Visit the Seattle Center/ Space Needle
Top things to do on a budget
- Pike Place Market
- Seattle Central Library
- The SAM's Olympic Sculpture Park
- Walk the Waterfront
- Take a Ferry Ride
Top things to do with a family
- Seattle Aquarium
- Pacific Science Center
- Pike Place Market
- Baseball/Football/Soccer Game
- Ride the Duck!
Darik Eaton , owner


text:
UMaine Highlights - Grants and Contracts: The Return on Investment in University-based Research
Total new dollars (MEIF + All Grants/Contracts/Gifts) available for R&D expenditures: $60,396,524 in FY13. UMaine used $11.6 million in MEIF funds to leverage $41,759,968 in external grants and contracts, specifically in the state's seven targeted sectors. (see table below).
|Table 1
|MEIF Leveraged New FY13 External R&D Grants and Contracts in the Seven Sectors
|State Technology Sectors
|Forestry and Agriculture
|Aquaculture and Marine Sciences
|Composite Materials
|Environmental Technologies
|Information Technologies
|Precision Manufacturing
|Cross Sectors
|Total Grants/Contracts/Gifts Leveraged
The increase in R&D infrastructure and activity has enhanced UMaine's capacity to spur industrial growth, with industry contracts for FY13 totaling $3,498,803 with 345 projects for companies.
UMaine submitted a total of 523 proposals during FY13, involving 325 faculty and professional staff as principal investigators or co-investigators from 56 departments or units. A total of $ 147,573,786 was requested from external sponsors.
Positions Leveraged
In FY13, 1,328 (FTE) UMaine job positions were created and/or supported as a result of MEIF funds, and external grants and contracts. This includes positions directly supported by MEIF funds, and people paid through R&D grants and contracts leveraged from the MEIF funds. It includes all job classifications.
Facilities and Equipment
UMaine continues to expand and develop state-of-the-art research facilities to support the targeted technologies.
More than $2 million in new equipment was procured to support UMaine R&D activity. Major purchases (greater than $25,000) through various FY13 grants included pieces of scientific equipment. This equipment outfits labs throughout the university.
Planning, designing and construction continued and were completed on numerous facilities that were subjects of proposals funded by the National Science Foundation, the National Institute of Science and Technology, and the Maine R&D Bond competition (Maine Technology Asset Fund administered by the Maine Technology Institute), including the Innovative Media Research and Commercialization Center.
Increased Student Involvement in Research
UMaine graduate and undergraduate students are critically important to UMaine's research efforts. More than $6,358,941 from grants and contracts was used to support students in all sectors. Undergraduate students receive an hourly wage to work on research projects, while graduate students are paid stipends.
During FY13, Funds exclusively from external grants provided support for undergraduate and graduate students as follows:
- Salaries and wages: $5,001,942
- Tuition: $952,553
- Fellowships: $236,553
- Health Insurance: $167,893
This external funding continues to play a major role in offering affordable education and unique hands-on, real-world work experience to the students who participate in these projects.


text:
November 18, 2003
Coffee County-- It looks as if some animals have gotten lost and somehow made their way to South Georgia. The animals, rarely, if ever seen unless you travel thousands of miles to another part of the US, look woefully out of place. How did they get to a pasture on the western outskirts of Broxton, in Coffee County?
That question got answered recently, solving an animal mystery with pastures where unusual animals live behind tall fences on Bobby Mancil's farm. Ostrich, buffalo and elk live where people would just them of them as lost animals, but mean much more to Bobby. "I see a lot of pets," says Bobby Mancil who owns them. And, a lot of elk that people often mistakenly think are moose commonly seen out west and mid-west.
"Come on. Come on," says Bobby, coaxing a female elk who gently eats grass out of his hand. Elk still fascinate him ever since he started with four of them in 1989. His herd grew. "Probably close to 80," says Bobby, and they provide natural entertainment for him. "The young elk spar with one another, raise up on their hind legs and play. Occasionally, they slap one another," says Bobby standing near about 40 elk.
Bobby finds elk don't eat as much as cows. "Probably run three elk to one cow," says Bobby whose cows graze the same pastures as the elk. The elk have a hard time in July and August because of the summer heat, but the colder it gets, the more playful they become, splashing around in the pond on a cold day. He has a cabin near the pond where he sits for hours watching the elk play. "Yeah, they are fun to me, might not be to a lot of people," says Bobby.
He gets a lot of pleasure out of watching his animals be animals, even listening to them eat. A buffalo walks directly toward him, gently lowers his head and eats grass, lots of grass. "Sounds like he is really enjoying it like we would be eating a T-bone or something," says Bobby as he watches the buffalo eat a few feet from him. He noticed buffalo deal with hot weather differently than most animals. "They just sit down and chew their cud," says Bobby.
The buffalo don't hunt for shade like most animals do in the summer. They stop where they are and tough it out. It was Bobby's natural curiosity that prompted him to buy a buffalo for a simple reason. "Just to look at," says Bobby. And listen to. "Enjoy the animals as a whole," says Bobby as he sees elk in the far side of the pasture and the buffalo in front of him.
Bobby worked out west where he saw buffalo and elk everyday and realized, "I'd really like to have some of those," says Bobby. He followed his dream, making it come true, bringing the animals to his farm, where he could listen to the unusual sound of a mama elk talking to her baby, and seeing buffalo roam on his farm where seldom is heard a discouraging word and the skies are not cloudy all day.
Bobby Mancil finds people like elk meat because it's tasty, low in fat and cholesterol. People who live in the Orient buy ground-up Elk horns to treat various ailments.
posted at 3:20PM by email@example.com
P.O. Box 3130
Albany, GA 31706
(229) 446-1010
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(229) 446-4005
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text:
Elegant Architectural Cabin & guest cabin w/ pool in Sequoia
- bedrooms 3
- baths 3
- sleeps 10
- pool yes
- hot tub no
- pets allowed yes
- type Cabin
- community Springville
rates (USD)
/ night
$ 1,450 - $ 2,670 / week
vacation rental description
**Special** FREE pool heating Oct and May (if needed) with 3 night or longer stay (Holidays excluded)
**Spring break Special** FREE pool heating in April for stays of 4 nights or longer
There are 2 cabins on this property both with high beamed ceilings and open floor plans well suited to gatherings of family and friends. The main cabin sleeps 4 in 2 bedrooms and 2 on a sleeper sofa in living room and has 2 full baths. A guest cabin is available for an additional charge (or rented alone with use of pool and game room--last minute only when main cabin is not rented) which sleeps up to 4 on a King and 2 twins and has 1 full bath. Together both cabins will sleep a maximum of 10.
This spacious cabin and guest cabin sit on a private, peaceful, gated 2 acre estate bordering Giant Sequoia Ntl. Monument and is only 12 miles from the Big trees, lakes, rivers and waterfalls at Balch Park. These unique solar-powered cabins boast a spring water swimming pool, billiard room, travertine double shower and claw foot tub and high exposed beam ceilings. High speed Internet / Wifi available. Hike from your back door!
vacation rental location
property availability
- dates with deals
- unavailable dates
Last modified on 08-30-2014 at 11:21 AM.
email owner view full calendar
Shelly McKnight 559-539-2286
cabin rental amenities
This property has beautiful park like grounds with outdoor activities such as swimming pool, tether ball, ping pong and hoop shooting. Indoor game room has a full size Billiard table and Tornado Foosball table.
Washer and dryer, fridge with icemaker, new dishwasher, ceramic cooktop, coffee maker, microwave, coffee grinder, blender, propane barbeque, large screen TV, DVD collection, games, toy boxes are all provided.
Free Wifi, iPod stereo, high chair, wood stove and firewood, luxury linens, towels, beach towels and down comforters are all provided.
activities and attractions in Sequoia High Sierra/Gold Country
Avoid hectic tourist crowds and discover the quiet beauty of the Giant Sequoia forests, rivers, lakes and waterfalls in Balch Park and Mountain Home State Forest within Sequoia National Monument. Ride horses among the Giants, hike, fish, bike and cross country ski. This cabin is located near the picturesque village of Springville with restaurants, shops, local entertainment, a new park and visitors center. Come for the Springville Sierra Professional Rodeo and Jackass Mail Run Weekend in April, wildflower touring March through May, bull riding events in August and Apple Festival in October.
vacation rental rates
This property will accommodate a total of 10: 6 in the Main Cabin and 4 in the guest cabin
Main Cabin (2 bed/2 bath + sleeper sofa) 6 persons maximum in Main Cabin
June - August and Major Winter Holidays $1650/wk, $275/nt for 4 persons
$15/person/nt additional for up to 2 additional persons in main cabin (6 total) -- 4 night minimum
September, October & May $1500/wk, $250/nt for 4 persons **SPECIAL** $225/night for 1 couple only in Main Cabin
$15/person/nt additional for up to 2 additional persons in main cabin (6 total) -- 3 night minimum
November - April (excluding holidays) $1400/wk, $225/nt for 4 persons
$15/person/nt additional for up to 2 additional persons in main cabin -- 2 night minimum, 3 night minimum March 28 - April 20
Guest Cabin (1 King and 2 twins in one large room with bath and kitchenette)
$600/wk, $95/nt for 2 persons + $15/person/nt additional for over 2 persons in guest cabin 4 persons maximum
We accept MC, Visa, Discover, PayPal, or Personal Check
Pool heating (Oct, Nov, April, May) $50 start up + $30/day for propane--2 day minimum
**Special** FREE pool heating Oct & May (if needed) with 3 night stay or longer (Holidays excluded), April is free with a 4 night stay or longer
$300 refundable damage deposit--$60 pet cleaning fee--$75 cleaning fee
2 dog maximum
Shelly McKnight 559-539-2286
accepted payment methods
Prior to paying a reservation deposit, always verify payment instructions by calling the phone number displayed on this listing page. By contacting the owner directly and paying by an approved method - credit card, paypal, check or bank transfer - your reservation payment will be protected up to $1,000.Learn more in our Security Center
Top things to do in Sequoia
- Hiking
- Swimming
- Horseback riding
- Cross country skiing
- Driving Tours
Top things to do on a budget
- Hiking
- Swimming
- Fishing
- Driving Tours
- Cross country skiing
Top things to do with a family
- Hiking
- Swimming
- Picnicking
- Horseback riding
- Sledding
Shelly McKnight , owner


text:
CATEGORIES MoviesJulie Delpy and Ethan Hawke have been together for 18 years -- well, on-screen that is.
The stars of Richard Linklater's "Before" trilogy stepped out last night to celebrate the premiere of "Before Midnight," the conclusion to the drama- and romance-filled series, in L.A.
Delpy looked radiant in a red, lace-embroidered dress, accessorized with matching red lips, while Hawke wore a classic navy suit and button-down shirt.
As mentioned, "Before Midnight" is the final installment of writer-directer Linklater's story about Celine (Delpy) and Jesse (Hawke), two strangers who met, and fell in love, on a train to Vienna almost two decades ago in the film "Before Sunrise." The sequel to "Sunrise," "Before Sunset," caught back up with Jesse and Celine nine years later in Paris, after Jesse had written a book about their encounter. In "Before Midnight," we find the couple in their early 40s, in Greece, taking on the hurdles of marriage and parenthood.
Hawke and Delpy not only star in the movie, they also co-wrote it with Linklater.
Check out the photos below. "Before Midnight" opens May 24.


text:
DescripciónUse your device's camera LED as a Flashlight. Supports devices without LED also by using device's display as a light source.
Increadiblly simple interface with three modes of operation.
Flashlight Permissions:
-The App will use the Camera Permission. The app uses the camera LED/flash and thus needs this permission.
-In case the App crashes it will provide a choice to user to mail the crash report to the developer. This will facilate us to upgrade the app with better version.
The user can opt out of this by pressing back key when asked. No personal data will be accessed in any case.


text:
A crop of American cockroaches brings in serious cash.
Four people are still
recovering from a vicious dog attack in north Toledo that occurred Monday
There wasn't just one
attack, but two, and the woman attacked both times says she feels bad for the
A dog attacked four people
on East Hudson Street off of Lagrange Monday night, but Jane Poore says the dog
first lunged at her neck just before 3 p.m.
"He grabbed me by my
sweater and drug me to the ground," she said.
Poore suffered no bites,
but about five hours later, she had just finished taking her garbage out when
the same dog attacked her again, this time tearing into her leg.
"The dog continuously bit
me and bit me," she said. "Then returned to bite my son again."
She said her two sons came
out to help, but were also attacked. Cody Hoffman has serious arm injuries, and
Corey Poore was bit on the leg. Their friend, Robert Cantua, was hospitalized.
Toledo Police were forced
to shoot and kill the dog.
"It's a shame that the dog
had to be put down," Poore said. "Even after what it did. It's not the dog's
fault, it's the owner's fault."
Lucas County Dog Warden
Julie Lyle says the dog's owner, Mary Taylor, was cited for failure to confine
the dog.
Lyle also said they hadn't
received previous calls about this dog, but Poore says it had been menacing the
neighborhood for months.
Copyright 2013 Toledo News
Now. All rights reserved.
730 North Summit Street
Toledo, OH 43604
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text:
Attempting to revive their dialogue with Tamil Nadu Chief Minister Jayalalithaa over Kudankulam Nuclear Power Project issue, anti-nuclear activists have expressed their willingness to initiate a "fresh round" of talks with her.
Activists of the People's Movement Against Nuclear Energy in an open letter to the Chief Minister said: "...As we have completed a whole year struggling against the KNPP, we would like to initiate a fresh round of dialogue with you."
Requesting her to "turn the KNPP into a pro-people and nature-friendly project, bring about solar power policy and projects all over the state," the activists said they were looking forward to "favourable actions" from her.
PMANE activists, including S.P. Udayakumar, M. Pushparayan, and Fr F. Jayakumar, have made the request.
Jayalalithaa had yesterday renewed her demand to Prime Minister Manmohan Singh that the Centre allot the entire 1,000 MW to be generated from the first unit of Kudankulam Nuclear Power Plant to the state, and hoped for a "quick response''.
In a letter to Singh, she recalled her previous communications to him on the issue and pointed out that there was no response to her letters.
The Atomic Energy Regulatory Board had recently given its approval for loading the real fuel in the first reactor of nuclear plant, taking the controversy-hit project a step closer to commissioning.
The commissioning of the first of the 2x1000 MW units of the Indo-Russian project in Tamil Nadu's Tirunelveli district was slated for December last year but protests by local people, spearheaded by PMANE, on grounds of safety concerns have delayed it.