text:
Strictly Hip Hop with Florida, DropaJewel, and Miss J Nyce.
Mon-Thur, 5pm- 7pm
Strictly Hip Hop is a program that has aired on WEAA's 88.9 FM for 22 years. We exist to introduce, and preserve the urban hip hop culture to a vast demographic. The show contains various segments including: Question of the Week, The Test Bin, news, Changing the Game, One 2 Flow On, and mixes from local DJ's. Our staff consists of Morgan State University Alum and current Morgan State University students in addition to freelance hip hop enthusiast throughout the Baltimore Hip Hop scene.
Strictly Hip Hop is held in high regard, as we are the longest running hip hop show in the state of Maryland. The efforts of the SHH team were recently recognized by the City Paper's 2010 Best of Baltimore Awards, the 2011 Baltimore Music Awards for "Radio host of the year," 2011 Baltimore Crown "Special Appreciation" and more! The show is constantly changing to stay relevant with the evolution of hip hop, while still accommodating our already colorful demographic.
As of today, the key players at Strictly Hip Hop are:
Florida-Main Producer/Host
DropaJewel-Coordinator/Media Director/Co-Host
Miss JNyce- DJ/Engineer/ Co-Host
We have a staff of the most professional DJ's including: DJ Mike Nyce, DJ Booman, DJ Trell Trell, and of course DJ Miss JNYce.


text:
|MMA Playground 4.0 is live! Returning members: check out the patch notes New members: visit our getting started guide, read the FAQ's and start playing!
diazsweedman Profile | diazsweedman Pick'em History | Event Leaderboard | Season Leaderboard | Last Page
Fighters labeled as "Heavy Underdog" reward a +2 point bonus when they are picked and win their bout.

subset: commoncrawl


text:
Greensburg —
When Mel Fox stepped away from politics last year, she'd experienced enough of the deep political divides and polarization that defines modern US government.
As Fox herself admitted, however, public service is woven into her DNA. Public service, in fact, is part of her family legacy.
During a brief phone interview Tuesday afternoon, she told the Daily News, "I am Ovid Butler's niece, five generations removed. My Great-Great-Great grandmother, Mary, was Ovid's sister."
Ovid Butler, of course, was the founder of Indiana's Butler University. When Fox finally moved out of the glaring, incendiary light of modern politics, she knew she couldn't go long without stepping into some public service role.
"Servanthood is part of the 'Butler Way,'" she said, referring to a core system of beliefs first laid down by legendary Butler Basketball Head Coach Tony Hinkle decades ago.
Those principals, according to Fox, are: Humility; passion; unity; servanthood, and thankfulness.
The Butler Way, she added, was in actuality, first practiced by Ovid Butler and has been part of Butler University's lifeblood since its founding in 1855.
Fox's main outlet to practice the Butler Way has come in the form of service to the Decatur County Emergency Management Agency (EMA).
Considering the weather catastrophes plaguing the state in recent years, for Fox, service to the EMA is critical to Decatur County's future — indeed, to Indiana's future. When it comes to weather, Fox agreed, Decatur County has been waiting for "the other shoe to drop," over the last few years, making it vital to be prepared when the next emergency strikes.
"It's amazing to me," she said, "how, since the May 2011 tornado, our local EMA has come together and become a shining example for the region and the state."
For a reminder of why she first entered the public-service arena, though, Fox turns back to her lineage. The Butler Way, she said, offers an important reminder that modern, polarized politics don't reflect the true nature of or the fundamental ideals one should adhere to as he or she enters public service.
On February 7, Fox spoke at the Annual Butler University Founder's Day, which celebrates both Butler University's founding and Ovid Butler's birthday; 2013 marked 212 years since Ovid Butler's birth.
"If you look back on Ovid Butler's life," Fox said, "you quickly see that he was ahead of his time. He was a big believer that we, as human beings, should respect one another regardless of race, sex, color, religion, political affiliation and the multiple other things we find to discriminate against each other."
"Butler University," she added, "was only the second school in the nation to allow women and people of color to have the exact same education as white men."
Fox is proud, too, that both Ovid Butler and the university named in his honor can lay claim to Greensburg roots.
Ovid Butler, she said, opened his first law practice in Greensburg.
"It was a miserable failure," she explained. "In fact, he fell flat on his face, but he kept moving forward and found great success a little later practicing law in Shelbyville (he was Shelbyville's first lawyer) and Indianapolis with Calvin Fletcher (Indiana's first lawyer and the founder of the Fletcher Bank)."
The 1847 vote establishing and laying the foundation for Ovid Butler's University occurred right here in Greensburg, Fox said, at the Disciples of Christ Christian Church.
It took another six years for Ovid Butler to raise $75,000 to open his school, but, in 1855, the Northwestern Christian University finally accepted its first student.
"They changed the name to Butler University in 1877," Fox explained. "And Ovid hated it. He strongly protested the name change, because he was a gentleman with the utmost humility, which is a value of The Butler Way."
"The Butler Way," she concluded, "should be the way of the world."
Contact: Rob Cox at 812-663-3111 x7011.


text:
Dan Radcliffe Interviewed by GQRadcliffe
We now have scans of a new interview with Dan Radcliffe (Harry Potter) featured in GQ magazine here in our galleries. This interesting interview spans Radcliffe's last few months on the set of "Deathly Hallows," to filming "The Woman in Black," to performing in "How to Suceed in Business Without Really Trying." Page one of the interview is here, page two is here, page three is here, and page four is here. There is some strong language in the article, so please be forewarned.
Thanks very much to SnitchSeeker!


text:
Page 9 - Cedartown Apartments for Rent(show city information)
Apartment Finder is the ultimate tool for searching for apartments for rent in the Cedartown, GA area. With map-based searching, you'll find just what you are looking for in minutes. You can customize your search many ways and your results will be refreshed in a flash. Browse apartment communities in real time, with photos, floor plans, and more! Your search for Cedartown, GA apartments is over. The Apartment Finder features include faceted browsing, map-based search, and search results by neighborhood, county, university campus, military base and more. If you are seeking a Cedartown, GA apartment for rent, you have come to the right place.


text:
SATO's Prestige Partner Program provides a framework of business for growth and profit with SATO America products, services, and solutions. The program is a tiered solution for the complexities of business today, yet will afford your company a wider range of product and solution availability than most other industry programs.
Business Solutions Exclusive: ScanSource's Dixon Talks Everything Channel
One of the chief lessons I've learned from smart channel executives the past 15 years is this: sometimes you need to stop working on the day-to-day of your business and get educated on the most important trends that could affect your business.
What Every VAR Needs To Know About The Healthcare Vertical
Paul Constantine, President of ScanSource POS/Bar Coding North America, talks with Jameson Publishing and Business Solutions magazine President Jim Roddy in this exclusive Executive-To-Executive interview conducted at the 2013 ScanSource Partner Conference in Austin, TX.
Ingram: Greater VAR Profits Rooted In Total Solution
Brian Wiser, senior VP of specialty solutions at distributor Ingram Micro, and Justin Scopaz, general manager of Ingram Micro's Data Capture/Point Of Sale/Physical Security division, talk with Jameson Publishing and Business Solutions magazine president Jim Roddy in this exclusive Executive-To-Executive interview.
- Exclusive BSM Interview: New ScanSource POS/Barcoding President Paul Constantine
- Ingram To VARs: Focus On The Total Solution
- Emerging Trends In The AIDC/POS Channel
- Mobility's Role In The Total Solution
Seagull Scientific Features BarTender Software At Smart VAR Healthcare Summit
David Rau, director of sales, Americas for Seagull Scientific, discusses BarTender software at the Smart VAR Healthcare Summit held on May 6 in New Brunswick, NJ. The software enables data from EHR systems to be partitioned and added to a wristband or label — with the option of applying color.
Cognitive TPG Demonstrates Printing With Security Features
At the Smart VAR Healthcare Summit held on May 6 in New Brunswick, NJ. Joe Howe, business development manager for Cognitive TPG, his company's printers' ability to print special security features on plain, thermal paper.
MCL Technologies Demonstrates App Development Tool At Healthcare Summit
Susan Krusee, AMERICAS sales director for MCL Technologies, met conference attendees at the Smart VAR Healthcare Summit held on May 6 in New Brunswick, NJ. She provides information about MCL-Designer, a rapid app development tool/mobile platform cloud computing tool.
- Datalogic: Healthcare Providers Are Adopting, Upgrading Technologies
- How Citizen Printers Are Used For Healthcare
- Zebra Technologies: Bar Coding Is Bridge Between Patient And EHR
- ASAP Discusses Asset And Inventory Management For Healthcare At Smart VAR Summit
Sales Is Still A Numbers Game
But, the numbers that you need to monitor and measure have changed dramatically, and I do mean dramatically. Back in my early days of selling for IBM, one of our management's mantra was "calls plus presentations equals sales," and that worked.
- What To Look For When Selecting A Bar Code Printer
- 4 Commonly Overlooked Recurring Revenue Streams In Mobility
- Tips For Using Storage To Enable A Business
- The Real Difference Between Business Tools And A True PSA


text:
Benfica TV Live is the pay-per-view service of Benfica TV.
It's a paid service, which allows you to watch the broadcast of the Sport Lisboa e Benfica first team home matches of the Portuguese League.
Online streaming video is for residential customers only and is not permitted for viewing in commercial establishments such as bars, restaurants or clubs. Violators will be prosecuted.
Live Stream of the Sport Lisboa e Benfica Portuguese League first team home matches.
Benfica TV Live is available in the following countries:
The access to the contents will be available after registering and subscribing to the website.
If you are not registered yet, and you are not a member click here to do your registration.
If you are not registered yet, and you are a memberclick here
In case you are already registered, you only need to subscribe to the service. Click here to know our offers.
To obtain or recover this information you must use the password recovery on myBenfica. Click here to recover your data.
PC (Windows, Mac OS X, Linux), mobile devices (Windows Phone, Android, iOS) and tablets.
Credit card and PayPal.
The quality of the streaming is calculated through the user's bandwidth available to always receive the best quality without any flaws.
We recommend you to have at least a broadband Internet connection (DSL/Cable or better) of 750 kbps to enjoy the broadcasting with the maximum quality.
Every subscription is limited to one device registered by each user.


text:
For much of the 2010 campaign, Bengals WR Andre Caldwell had a reduced role in the offense.
"I just had to keep grinding," Caldwell said two days before Easter, reflecting on the past season — one that ended much better than it started, when he lost his role as the primary slot receiver to rookie Jordan Shipley.
But when Terrell Owens left the lineup with a knee injury in December, Caldwell stepped into the starting lineup and produced. He was targeted 22 times in the final three weeks of the season, catching 15 passes for 270 yards (18.0 avg.).
Owens, who is slated to be an unrestricted free agent and seems unlikely to be back in Cincinnati, nonetheless had a major impact on the Cincinnati offense in 2010, leading the Bengals in catches, receiving yards and receiving TDs playing the "Z" position. Owens' presence, Caldwell said, "transformed that position."
When Caldwell stepped in, he found himself getting more one-on-one matchups, and he received more chances to stretch the field — something he often didn't get a chance to do playing the slot. In the final four games of the season, Caldwell had four catches of 20 yards or more — two more than he had in all of 2009, when he caught 51 passes for an AFC North-winning club.
Caldwell is among a group of Bengals wide receivers who have worked out with QB Jordan Palmer in California. Carson Palmer, Jordan's brother and the Bengals' starter the past seven seasons, no longer wants to play for Cincinnati. Caldwell told PFW that he has not spoken with Carson Palmer, but he knows his teammate is "passionate" and must be taken seriously.
"When he says something, he means it," Caldwell said.
Caldwell told PFW he hopes Carson Palmer is back with the team, but he knows that might not happen. In the meantime, the Bengals' wide receivers work to get their timing down with Jordan Palmer.
Caldwell wants to keep a major role in the offense, which is switching to a West Coast scheme in 2011, and he believes he fits the new attack well, noting that he believes Jay Gruden's offense is designed to "get the ball in a player's hands, let them make plays."
"I think it works in my favor," Caldwell said of the new offense.


text:
Advanced Search |
Search Tips
Shop our online gallery of Cityscape wall murals to add an urban touch to your walls. Powerful, exhilerating and modern, Cityscape wall murals will also bring a dramatic depth to any smaller room. From Paris to New York, from Tokyo to Chicago, you will be sure to find the most impressive skylines from around the world.
Cityscapes Wall Murals
Feel the rhythm of the most fascinating cities in the world through our selection of Cityscapes Wall Murals. Do you dream of having trendy and modern wallpaper featuring the most famous buildings of New York, the city that never sleeps? Or perhaps you prefer a breathtaking view of the rooftops of Paris, marvelling the splendors of the most beautiful city in the world? You can also find murals of Tokyo, Chicago, London, Sydney, Montreal and many, many more! With Eazywallz photo murals and photo wallpaper, capitals and major cities are now at your finger tips! Featuring powerful and sophisticated images, this collection can be displayed anywhere in your home, as it will easily bring dimension to your walls and depth to any room in the house. By choosing our Cityscapes Wall Murals you can immerse yourself in an oversized setting, giving the illusion of a much larger space. To add an even more dramatic impact, consider cityscapes at night!
We print all our Cityscapes wall murals on our original and innovative self-adhesive woven fabric. If you are looking for an easy solution to transform the look of your walls and the decor of your room, you are at the right place! Our wall murals, wallpaper murals and photo murals are extremely easy to install and can as easily be removed if needed. As well, our custom section offers you a fun way to personalize your wall murals just the way you want it. Plus, we offer FREE Shipping on every order across Canada and continental United States!
If you are seeking breathtaking wall murals, look at our selection of extra-large Panoramic Wall Murals >
All prices are in USD
Copyright 2014 Eazywallz .
Sitemap |
Terms and Conditions


text:
Developed by
X-Universe News
Developer Network
Buy X-Series online
X Rebirth 2.0 - Secret Service Missions now available
(56 Comments)
Egosoft is extremely pleased to finally announce the release of
X Rebirth 2.0 - Secret Service Missions
. After considerable effort and with an eye to all the great feedback we've received, X Rebirth 2.0 represents a major update for a wide variety of gameplay mechanics.
Together with the new plot chain, which offers all players membership in the Argon Federation secret service, X Rebirth 2.0 brings a host of new features and improvements.
For a more detailed explanation of the new features, please have a look at the
X Rebirth 2.0 Feature manual
The patch will be installed via Steam immediately. More information and a full list of its content can be found here:
News and Patch Information
posted by BurnIt!
X Rebirth 1.31 now available
(30 Comments)
We have just released an update the brings X Rebirth up to version 1.31.
This is just a small update to fix various problems reported by some players.
Fixed further problems with ship and station build, upgrade and repair processes.
Fixed crash when starting game with more than 4 joystick devices installed.
Fixed several other causes of occasional crashes.
Improved handling of pre-1.30 savegame compatibility problems caused by mods leaving files in the root extension folder.
Improved error reporting in crash dump files.
posted by BurnIt!
X Rebirth 1.30 now available
(30 Comments)
We are happy to announce the availability of patch 1.30 for X Rebirth. Among the many new features and fixes are the following highlights:
Support for the
Steam Workshop
so mods can now be easily installed. Find out more here:
Steam Workshop for X Rebirth
Upkeep missions to help you keep track of stations that you own.
"Styrvok" ships in DeVries
The patch will be installed via Steam immediately. More information and a full list of its content can be found here:
News and Patch Information
posted by BurnIt!
X Rebirth 1.25 and News Update
(95 Comments)
This week we have several new things for you. Our 1.25 update introduces a couple of important new features. We also have a
explaining some of the things we've added recently to X Rebirth and a
news update
telling you more about our plans for the next few months.
posted by CBJ
X Rebirth is finally here!
The time has come: after seven long years of development, X Rebirth is finally available.
X Rebirth marks a new beginning in the history of the X Series and draws fans new and old into an unbelievely large, living and richly detailed universe, just waiting to be explored.
Once again, underpinning X Rebirth are the four long-standing and familiar cornerstones of the X Series.
A fully simulated economy in which every action has consequences. Every ship you see has a task. Stop a freighter from reaching its destination and its cargo will be stopped too, causing prices to rise.
From small scale skirmishes to epic fleet encounters, battles in the X Universe know no limits. Choose to fight for the military, work for the police or be a lawless pirate, or if you prefer just fight when you need to defend yourself - it's up to you!
Create your own empire! From trading stations to large factories, farms to high-tech military complexes, everything can belong to you.
A rich, detailed history and a deep complex plot await you, but you are free to decide when and where to take part.
Action-packed space battles, a realistic trading system and many opportunities for exciting discovereies as you travel the universe, mean you can enjoy a unique space opera with countless hours of gameplay.
This release is the start of a whole new journey, and we hope that you will join us in populating and shaping the universe over the years to come. We have a long history of working with our player community, through rough and smooth, and doing our best to turn their hopes and ideas into reality. We hope that you will share your views and feedback with us and help us to improve and expand the new X Universe as we add new features as well as solving any problems you may run into.
In the next few weeks we will also be reopening our DevNet Ideas forums, where you will be able to show us your ideas for the future.
But enough talk. To your cockpit, and may your deeds restore the "Albion Skunk" to its former glory as the "Pride of Albion"!
We hope you enjoy X Rebirth!
November 2013, Bernd Lehahn, Managing Director, EGOSOFT GmbH
posted by CBJ
X Rebirth orders from the Egosoft Shop have been sent out
(24 Comments)
We have now finished sending out all German X Rebirth and X Rebirth CE orders paid for before November 14th, and all English X Rebirth CE orders paid for before November 8th.
posted by CBJ
X Rebirth - Фюёђѓяэр я№хфчру№ѓчър т Steam
(260 Comments)
Фюёђѓяэр я№хфчру№ѓчър т Steam
Юёђрырёќ тёхую 1 эхфхыџ фю №хышчр шу№ћ X Rebirth. Я№шјыю т№хьџ я№хфюёђртшђќ я№хфчру№ѓчъѓ т Steam.
Хёыш тћ ѓцх ръђштш№ютрыш т Steam X Rebirth, ђю тћ ѓцх ьюцхђх эрїрђќ ѓёђрэютъѓ шу№ћ. Ъръ ђюыќъю тћщфхђ т ётхђ X Rebirth, р §ђю эрьхїхэю эр 15-юх Эюџс№џ, тћ ёьюцхђх ё№рчѓ эрїрђќ шу№рђќ.
posted by BurnIt!
Юу№рэшїхээюх ъюыыхъішюээюх шчфрэшх - ёђрђѓё ьрурчшэр нуюёюєђ
(260 Comments)
Эрјр ях№трџ яр№ђшџ
Рэуышщёъюую ъюыыхъішюээюую шчфрэшџ
X Rebirth
сћыр №рёя№юфрэр; Эю ьћ ёьюуыш ёюѕ№рэшђќ §ъёъыўчштэѓў тђю№ѓў яр№ђшў. връ їђю Тћ юяџђќ ьюцхђх чрърчрђќ Рэуышщёъюх ъюыыхъішюээюх шчфрэшх т
эрјхь юэырщэ ьрурчшэх
. Ъ ёюцрыхэшў, шч-чр ыюушёђшїхёъшѕ ђ№ѓфэюёђхщ ё я№юшчтюфёђтюь тђю№ющ яр№ђшш ьћ, тючьюцэю, эх ёьюцхь фюёђртшђќ чрърчћ, ёфхырээћх яюёых
6ую эюџс№џ
фю ъюэір ьхёџір! Хёыш цх Тћ ёфхырыш чрърч фю §ђющ фрђћ, ђю эх тюыэѓщђхёќ, Тћ яюыѓїшђх шу№ѓ шч ях№тющ яр№ђшш ш ьћ юђя№ртшь трј чрърч ъръ ђюыќъю ёьюцхь.
Ъюэхїэю цх, Тћ тёх хљх ьюцхђх чрърчрђќ ёђрэфр№ђэѓў сюъёютѓў тх№ёшў Эхьхіъюую ъюыыхъішюээюую шчфрэшџ; эю шѕ їшёыю ѓьхэќјрхђёџ сћёђ№ю, ђръ їђю ёютхђѓхь яюђю№юяшђќёџ ш ёфхырђќ чрърч, хёыш тћ хљх эх ѓёяхыш.
Юэырщэ ьрурчшэ Egosoft
posted by BurnIt!
X Rebirth Collector's Editions - Full content revealed
(894 Comments)
Heads up, fans of the space saga X: Deep Silver and Egosoft are releasing a
limited Collector's Edition
of the latest installment
X Rebirth
. The extensive package includes the game itself along with exclusive contents: The blu-ray disc "X the Space Opera Per Musica ad Albion" contains unique pieces of music composed specially for the game. There is also a soundtrack CD featuring 26 tracks. A 56-card pack of playing cards with motifs from the X Universe, a 28-page art booklet and other exciting extras round off the package.
The exclusive contents of the
limited Collector's Edition
is as follows:
"X the Space Opera Per Musica ad Albion" + extensive "Making of" on blu-ray
Exclusive soundtrack audio CD
Pack of X playing cards (56-card Quartets pack)
Removable sleeve
X LED flashlight
Update of the official X Encyclopedia for filing plus digital version
10 large-format postcards featuring artwork from the X Universe
Art booklet including unpublished concept art (28 pages)
"Albion Skunk" sticker
Double-sided poster (36x48 cm)
Full-color manual
The German Collector's Edition will also come with an extract of the newest novel based on the X-Universe -
Plutarch Rising
- by Helge T. Kautz.
The Collector's Edition of X Rebirth will be released along with the regular retail edition on November 15, 2013, and will be available in the following territories:
In the UK at a price of GBP 59.99
In Germany, Austria and Switzerland at a price of € 64.99
In France at a price of € 59.99
The X Rebirth Collector's Edition is now available for preoder from the
Egosoft Shop
Steam X Rebirth Collector's Edition:
For all those who are more interested in a digital version, there is the
Steam X Rebirth Collector's Edition
. This comes with:
Soundtrack Volume 1 (MP3)
Exclusive: Soundtrack Volume 2 (MP3)
Optional download: X - The Space Opera - Per Musica ad Albion (Video)
Bonus download with artworks and X encyclopedia
The Steam X Rebirth Collector's Edition is available at a price of € 64,99 from the
X Rebirth Steam website
If you already activated the regular edition of X Rebirth on Steam you can pre-purchase the
Collector's Edition Upgrade
, giving you access to all the extras of the digital Collector's Edition.
US Limited Edition:
For all our fans from North America, our North American Publisher TriSynergy has an own version ready for Pre-Order: The
X Rebirth Limited Edition
. This comes with the game on DVD, a printed manual, a printed Art Book with Concept Arts and a
Bonus DVD
The updated X-Encyclopedia as an ebook
The extensive "Making of" X Rebirth
The exclusive X Rebirth Soundtrack
The X Rebirth Limited Edition is available for Pre-Order at a price of
from the
TriSynergy shop
and will be shipped on the
15th November
posted by X2-Illuminatus
Find older news in our archive...
Users: 446564
Logged in: 54
Latest Screenshot
X Rebirth
X³ Albion Prelude
X: Superbox
Disclaimer / Impressum
Copyright © EGOSOFT 1990-2014


text:
CELEBRATE OPPORTUNITY - An Executive Networking and Business Recognition Luncheon
Opportunity Partners
Wednesday, February 27, 2013 from 10:30 AM to 1:00 PM (CST)
St. Louis Park, MN
JOIN US: February 27, 2013, 10:30am-1pm
If the success of your business relies on meeting and networking with many of the top decision-makers in Minnesota, you don't want to miss:
An Executive Networking and Business Recognition Luncheon
Emceed by WCCO-TV's Frank Vascellaro, CELEBRATE OPPORTUNITY will feature keynote speaker Chris Wright, President of the Minnesota Timberwolves, a Business Partner Showcase, two executive networking sessions and a three-course luncheon.
Ditch the "if we win, they will come" mentality. In business, it's not about winning; rather, you need to build an environment where winners thrive. Chris Wright, president of the Minnesota Timberwolves, will deliver an unforgettable keynote presentation on Building Your Superstar Team, which takes center court the power of a "can-do" attitude in every team member. Combining this with marketing savvy, a passion for success, seeing the strengths and not weaknesses of every employee, and giving back to the community, can create an organization bound for success, even during tough times.
How Opportunity Partners helps Minnesota businesses, including DecoPac, EPCO, Walgreens, Coghlan's, Kraus-Anderson Construction and many more, increase productivity, increase their customer base, hire qualified employees and meet their community involvement and diversity goals.
A video from the 2011 Celebrate Opportunity event: http://youtu.be/ozx-ZgNGS4E
SPONSORS: Event sponsorship packages available here.
Media Sponsor:
Opportunity Partners serves more than 1,900 people, ranging from teens with brain injury to adults with Autism to seniors with Down syndrome. Services that help people live, learn and work are provided at more than 30 Opportunity Partners locations and hundreds of job sites and residences, helping people with disabilities to be in and of the community.
In order to purchase these tickets in installments, you'll need an Eventbrite account. Log in or sign up for a free account to continue.


text:
HAI Kink Crimp Iron
Sale Larger & More Views
$69.99 $39.99
Save 43% Free Shipping Free Gift
In Stock
Ships within 24 hours
HAI Kink Crimp Iron has plates with the perfect pitch angle to crimp, texturize, volumize and crimp. Ceramic plates infused with tourmaline create negative ion generation to conquer frizz and capture moisture to healthy styling. Plate measures 7/8 inches wide by 3.5 inches long.


text:
Tag Results for "Effects Of Secondhand Smoke"
Health Tip: How to Avoid Secondhand Smoke
April 6, 2012 | by HS News Staff | You and Your Health
Suggestions include asking people not to light up in your home. Secondhand smoke can cause illness and early death in adults and children who don't smoke. continue reading »
Displaying Tag Results Page 1 of 1


text:
I love the saturated colors and prints in these shots of Mia Wasikowska for Miu Miu! I barely recognized the Alice in Wonderland star, but I like how much brighter these are than those of Hailee Steinfeld crying on train tracks.
ciao + welcome!
F/24. Marketing/Graphic Design. Cookie connoisseur, Conan addict. Loves Roma, playing dress up, her dog family. Learn More
Social Media


text:
376 results total, viewing 21 - 30
Over the past weekend I found myself falling victim to the latest Hallmark movie channel premier. It all started on Saturday night when I joined my family in the living room. As I sat on the … more
Posted by Sherry Barnum | firstname.lastname@example.com
What's happening to me? If you were to ask me five or six years ago what would be a nightmare for me, it would probably be something along the lines of being anywhere near children. Just the thought of being in a room full of kids having fun gave me a headache. more
Posted by Tim Barnum | firstname.lastname@example.com
Clayton Township recently introduced trash pickup services, but only to township taxpayers who want the service. We applaud the way the township board went about bringing the service to its constituents. more
Posted by Independent Staff | email@example.com
| 10/30/13 | 3169 views
In just a couple weeks, young children, and some who are not so young, will celebrate Halloween. This holiday has to be one of the most fun holidays for children simply because its whole premise is a public stamp of approval to disobey parental and dentist recommendations and eat as much candy as is physically possible. more
Posted by Emily Walker | firstname.lastname@example.com
As our readers are probably aware, there are two different versions of our publications every week — our traditional print version that comes out once a week, and the online version that is updated daily. What you may not realize is, if you're only reading in print or online, you're not seeing everything we have to offer. more
Posted by Eric Young | email@example.com
Another 2-percent, class-three revenue sharing distribution is approaching in Arenac County, and for many local units of government and school districts, grants funded by that revenue will be helpful in improving their communities. more
10/16/13 | 1841 views
Though I don't share in the general loathing of the dentist office that's the norm among most of my friends and acquaintances, there are parts of my visits I find frustrating. more
Posted by Jessie Tobias
Since the office of the county drain commissioner announced it would be reactivating the long-dormant rolls for the Clam Drain — commonly known as the mouth of the Pine River — for dredging purposes, people all along the river have been questioning the necessity of the work. To prevent future flooding issues, however, we think it is an entirely reasonable project. more
9/18/13 | 1751 views
If you've read my columns over the past year or so, you may have noticed that I have openly talked about my hatred of bats and mosquitoes. Weird, I know, since bats eat mosquitoes. more
Posted by Tim Barnum | email@example.com
I was sitting in my fifth grade classroom in 2001 not knowing the impact that a single day could make on this country or the world. I sat there with no idea that terrorists had attacked the World Trade Center in New York, what terrorists were or even that the twin towers existed. more
Posted by Emily Walker | email@example.com


text:
Fundraising Toolkit
The following tools can help make your fundraising efforts a success. Download the individual pieces that will help you best publicize your fundraiser. (Select the link. Then right click on your mouse and follow your browser's instructions for saving the file to your computer.)
FORCE logos
FORCE brochures and jelly bracelets
Please order brochures and jelly bracelets from the FORCE Fundraiser Registration Form.
Disclaimer: Health links are made available for educational purposes only. This information should not be interpreted as medical advice. All health information should be discussed with your health care provider. Please read our full disclaimer for more information.
This site has been made possible by a generous grant from Morphotek.


text:
Log In
Add a message
Your e-mail
CNN's John King, a Babe granddaughter, and views of Tall Ships and the ballpark
photograph by yoon s. byun/globe staff
CAR TALK: Tony Dagata of Woburn and Carl Chiaretto (driving) of Medford at the Bay State Antique Auto Club's annual car show in Dedham, Endicott Estate on July 8
photograph by Matthew J. Lee/Globe staff
BEST SEATS: Dorchester-bred CNN correspondent John King, with son Jonah, before throwing out the first pitch at a Red Sox-Yankees game, Fenway Park on July 6
Photograph by Erik Jacobs
GLOWING: Alfred Megally of Cambridge and Lam Duong of Boston at Tango by Moonlight on the Charles River near Harvard Square, Weeks Memorial Footbridge on July 7
David L. Ryan/globe staff
SMALL WORLD: Passengers aboard the Full Moon charter yacht navigate a harbor still crowded with Tall Ships after July Fourth celebrations, Boston Harbor on July 5
FAMILY TIES: Claudia Williams, Ted's daughter, and Linda Ruth Tosetti, granddaughter of the Babe, before a Red Sox-Yankees matchup, Fenway Park on July 8
photograph by bill brett
ENCHANTED EVENING: Mariel MacNaughton, Erin Simpson Wayne, and Genevieve Klim, all of Boston, at an ICA First Fridays party, Institute of Contemporary Art on July 6
CHEERS: Philip Hillman II of Lincoln and Maggie Dey of Dorchester at Jerry Remy's overlooking Fenway Park for the roof deck's grand opening, Jerry Remy's Sports Bar & Grill on July 10
FLASH DIRGE: Musicians hold a New Orleans-style funeral outside WGBH Radio's Brighton offices to protest cutbacks in jazz programming, WGBH on July 5
Subscriber Log In
Don't miss any of your favorite stories again. Read the stories that matter to you as much as you want, whenever you want when you subscribe to BostonGlobe.com.
Get full access today for just 99¢
E-mail address:
Forgot your password?
Home delivery subscribers get free access. Link Account
Customer Service Number: 1.888.MY.GLOBE
Receive free unlimited access to BostonGlobe.com for the next two weeks! Get access
Enter your e-mail address below. We'll send you an e-mail with a link to reset your password.
E-mail Address
Return to login
Continue reading by subscribing to BostonGlobe.com for just 99¢.


text:
- Mobile site
- E-Newsletters
- News feed
- Find us on Twitter
Be first with breaking news
- Find us on Facebook
The Bolton News
All the latest news from Bolton
Armed robbers pick the wrong shop to raid - as they come up against shopkeeper who served in Iranian special forces (From The Bolton News)
Armed robbers pick the wrong shop to raid - as they come up against shopkeeper who served in Iranian special forces
Updated 10:55am Monday 13th January 2014 in News
A HEROIC shopkeeper who served in the Iran-Iraq war used a chair leg to scare off armed robbers who raided his shop in Little Hulton.
When two hooded men burst into Darius Adineh's convenience store he refused to hand over his hard-earned takings.
Instead he told the men "if you want the money you'll have to come and get it".
Mr Adineh, aged 44, was working alone when the two men, armed with a baseball bat, hammer and knife, came into his stop and made threats to kill him if he did not hand over the money.
He said: "One of the men came behind the till and he was very loud, using horrible language, effing and jeffing. I wasn't going to give my takings away, not even £5. Some shop keepers will say "take the money".
"But my wife and I work from 6am until 11pm seven days a week and we are struggling to pay the bills so why should I give them my takings from the till for them to smoke cannabis?"
Mr Adineh has run the Premier Convenience Store in Manchester Road East, Little Hulton, for three years and has never had to fight off robbers before.
He previously served in the Special Forces of the Iranian Army during the Iran-Iraq war and learned extensive military training. He is also a black belt in Kung Fu and continues to train.
The brave shopkeeper used a self-defence technique to protect himself by kicking one of the men in the leg. It caused the man to drop a hammer, which police later seized. He also kicked the man as he chased him out the store, causing the armed robber to try and grab items in the store to regain his balance.
Due to having back problems Mr Adineh was repairing a chair prior to the men bursting in so was able to deter them with a chair leg.
He said: "They didn't know they had come across somebody trained like me. Weapons don't scare me. I know how to disarm people. I am a trained ex-soldier.
" It was so easy for me to protect myself even if I just had a small pen because I know how to use it. I wasn't scared, it was all over within 16 seconds. I think they got more than a shock than me.
"I hope the message will be getting around criminals not to come again. They look for an easy target and I am not one."
He said a customer called police and they arrived within seconds.
Mr Adineh said customers are shocked about how they reacted as they always see him smiling and thought he was a "soft touch".
The men escaped empty handed following the raid at 10.10pm on Thursday.
One of the suspects was around 5ft 7ins, slim and was wearing a light coloured hoody with the hood up. He was wearing tracksuit bottoms that were also light coloured and had his face covered, possibly with some women's tights.
The second man was about 6ft tall, he was wearing a red hoody and had a local accent.
People with information about the crime can call police on 101 or Crimestoppers, anonymously, on 0800 555111.
Comments (15)
Please log in to enable comment sorting
2:28pm Sat 11 Jan 14
thomas222 says...
3:24pm Sat 11 Jan 14
tillyflop53 says...
3:41pm Sat 11 Jan 14
The bluetooth. says...
3:49pm Sat 11 Jan 14
ASIAN WHACC says...
4:33pm Sat 11 Jan 14
wsw69 says...
Scum like these two should be shot, or at least have their hands lobbed off. Let's hope something nasty awaits to beset the scum, and sooner than later.
5:59pm Sat 11 Jan 14
davidjb says...
7:54pm Sat 11 Jan 14
Citizen Cane says...
Well done Mr Adineh. It's a shame that you weren't polishing an AK47 when the scum arrived.
11:45pm Sat 11 Jan 14
p.rhanna says...
12:13am Sun 12 Jan 14
smiley111 says...
11:53am Sun 12 Jan 14
davroduk says...
Absoloutly brilliant.
Well done that man, pity you didnt do them more perminant damage.
3:12pm Sun 12 Jan 14
truth teller says...
6:22pm Sun 12 Jan 14
Lancashire always says...
11:37pm Sun 12 Jan 14
SleepingThunder says...
1:15pm Mon 13 Jan 14
cliff4treasurer says...
Works 6am to 11pm! the scum who did it probably never see that much daylight.
12:42am Tue 14 Jan 14
bernie boy says...
SleepingThunder wrote:Is that just an observation that you wished to impart upon us, or are you mistaking the Iranian Mr Adineh for an Israeli? I don't think he'd be too happy about that, rumour has it that those two creeds might not get along so well. He'll be after you with his chair leg if you're not careful.
Dont mess with them Isreal special forces.They teach them how to catch bullets in there teeth only 1 in every 1000 pass the selection process.
Comments are closed on this article.


text:
The Gluten-free diet is becoming more popular than ever. In the last 10 years, gluten-free items have become a household term and item found in many homes. According to a recent poll, nearly one third of adults said they wanted to cut down on gluten or have a gluten-free diet. News 2 spoke with a health educator to learn more about the real health benefits and risks of the diet that means avoiding foods made with wheat, barley or rye. "There is this huge craze now that you see in everything from restaurants to products that you buy in the grocery store that claims to be gluten-free," explained Vanderbilt University Medical Center health educator Stacey Kendrick. Celebrities such as Gwyneth Paltrow and Victoria Beckham have been linked to the gluten-free diet lifestyles which is said to contribute to increased energy, thinner thighs and weight loss. Kendrick said as with any diet or health regime, education is key. "A lot of people are really struggling with all of the nutrition messages that they hear out there," she said. According to Kendrick, only about one percent of Americans have celiac disease or gluten sensitivity. "If they eat anything with gluten, it makes them very sick," she explained. "Also they cannot absorb nutrients into their body, so it become a very serious health condition." Health experts, however, have said there is no evidence a gluten-free diet has any health benefits for those who do not suffer from gluten sensitivity. Kendrick told News 2 eliminating gluten from your diet can actually cause some negative health effects. "The reason is because there are many important nutrients and vitamins in products that contain gluten," she said. Kendrick urges that anyone considering a diet change to check with their health care provider before making any drastic changes. Last year, sales of gluten-free products hit $4.2 billion. That number is expected to reach more than $6 billion in the next five years.
441 Murfreesboro Road Nashville, TN 37210
Telephone: 615.369.7222
Fax: 615.369.7329
Email: email@example.com


text:
Poet and fiction writer Gerry Lafemina will speak at 7 p.m. Wednesday, March 5 at Clarion University (location TBA).
Lafemina is the author of 11 books of poetry, prose poetry and fiction. His most recent works are "Notes for the Novice Ventriloquist" (prose poems) and "Clamor" (a novel). He directs the Frostburg Center for Creative Writing at Frostburg State University, where he is associate professor of English.
View the entire Arts and Cultural Event's catalog here.
Starts On3/5/2014 7:00 PM
Ends On3/5/2014 8:30 PM


text:
Fall makes me feel alive, and winter is magical right up through Christmas.
Then I start to slowly suffocate under the double dose of darkness and cold.
After so many weeks of gray, it takes more than a few tulips in bloom to get me excited about life again. To me, spring has always seemed like a speed bump on the way to the perpetual sunshine and freedom of summer.
Then Wyatt came along and taught me that flowers bursting forth from the ground are kind of a big deal.
He always keeps a close watch on the buttercups that start growing wild around our yard at this time of the year. As soon as they reach the height of their beauty, he picks them for me, and I assign them a place of honor on our kitchen table.
It is impossible to overlook spring when a cute little guy is hand delivering it to you every week.
A recent trip to Birmingham Botanical Gardens to take some photos for the next edition of Walker Magazine also has me rethinking my stance on spring.
Executive director Fred Spicer was kind enough to give Beth Stukes and me a guided tour of the Japanese Gardens, where a new amphitheatre named in honor of Beth's mother is located.
First, we drove under the curved top torii, translated "gate to heaven." I learned later that a torii is used in Japan to mark the entrance of a sacred space.
This particular torii was dedicated in memory of Beth's grandmother, Elza Stewart Drummond, in the 1980s.
Beyond the entrance is a tunnel of Yoshino cherry trees known as the Kayser Cherry Walk. Some of them came from the famous cherry trees in Washington D.C., that were a gift from the people of Japan in 1912.
Spicer told us that the Japanese cherry, or Sakura, is a symbol of the fleeting beauty of life.
When the cherries are in bloom, the Japanese pay attention. They host flower viewing parties and festivals to celebrate this special sign of spring.
Weather forecasters predict when they will be blooming in various areas of the country so that people can follow the cherry blossoms the way we Alabamians follow fall foliage.
The American version of this sentiment is "Stop and smell the roses."
I am familiar with the expression, but I usually sprint through the garden without even noticing the roses.
In fact, I just realized that I have had a Japanese cherry tree under my nose for the past five years.
Several days after my trip to the Botanical Gardens, Zac and I were taking a walk with Wyatt when I spotted an array of white and pink blooms on a tree along the edge of the yard.
We have a perfect view of this tree from our living room window. It has bloomed every spring since Zac and I have been married.
I am sorry to say that I have never paid any attention to it, and it is likely that I would not be giving it any thought this year if not for the conversation with Spicer.
Now it is as if scales have fallen from my eyes. Every time I look out the window, I am reminded that life is as brief as it is beautiful.
While summer is still but a dream, the gift of spring is at hand.


text:
The Texans have announced that their home stadium will be known by a different name by the time football season starts. Read on to see what Reliant Stadium will now be called.
In the world! Until next year, anyway. But does it even matter?
The preview train keeps chugging along during the hot hotness of the hot Summer. Come for the baseless assumptions; stay for the Comments debate.
News out of Miami would seem to help Houston and Reliant Stadium's chances of getting to host another Super Bowl.
No surprise there, but it's worth seeing exactly how much of an increase we're looking at.
After years of complaints, Reliant Stadium will finally start using artificial turf for all non-NFL games. This is a promising development.
More details are reported about the death at Reliant Stadium during last night's Texans-Vikings preseason game.
The NFL announces a change in how fans can see replay at its stadiums. This is very, very good.
The BCS is dead, and the college football national championship game is up for grabs. Houston and Reliant Stadium want in.
Why is Reliant Stadium hosting a bowl game less than 24 hours before the Texans are scheduled to host the Titans?
As part of the new SB Nation launch, prior users will need to choose a permanent username, along with a new password.
Your username will be used to login to SB Nation going forward.
Please login to your Vox Media account. This account will be linked to your previously existing Eater account.
As part of the new SB Nation launch, prior MT authors will need to choose a new username and password.
Your username will be used to login to SB Nation going forward.
We'll email you a reset link.
If you signed up using a 3rd party account like Facebook or Twitter, please login with it instead.
You must be a member of Battle Red Blog to participate.
We have our own Community Guidelines at Battle Red Blog. You should read them.
You must be a member of Battle Red Blog to participate.
We have our own Community Guidelines at Battle Red Blog. You should read them.
Choose an available username to complete sign up.
In order to provide our users with a better overall experience, we ask for more information from Facebook when using it to login so that we can learn more about our audience and provide you with the best possible experience. We do not store specific user data and the sharing of it is not required to login with Facebook.


text:
Trade, talk and toys are all filling the Vegas Motel this weekend, as crowds come from all over the US for the 10th annual TTT Toy Show.
Venders from as far as Iowa came to the show this weekend to display, and in some cases sell their collector toys.
Model trucks, cars, planes, and even farm displays were out for crowds to check out today.
The co-host of the show says that even though it may not sound like it, it's an event that everyone in the community can come out and enjoy.
(Peter Thorp, Co-Host of Toy Show) "Even if you're not real big into that kind of stuff, it's still worth bringing the kids and coming to see, because there's a lot of unique stuff. Like I said, there's Hot Wheels, there's cars, there's just a variety of different things that you don't always have to buy. You can always just come and look, and you'll be surprised what you'll see."
The toy show will continue tomorrow at the Vegas Motel from 9:00 to 3:00.


text:
Book your room at The Marmara Antalya
Standard Room, City ViewMax Occupancy: 3 guests (up to 2 children, 2 infants)
Standard Room, Sea ViewMax Occupancy: 3 guests (up to 2 children, 2 infants)
Family Room, City ViewMax Occupancy: 5 guests (up to 3 children, 3 infants)
Hotel with private beach, full-service spa
Collect 200 points.*
Simply enter your Nectar card number on the confirmation page. Your points will be credited 30 days after your trip is complete. *Offers may apply
VIP Access™ Hotel
We carefully hand-picked this hotel based on its dedication to service and excellent guest reviews.
At VIP Access hotels, our elite customers are invited to enjoy the free room upgrades and other benefits upon availability at check-in.See details
This Antalya hotel is located by the sea, offering direct access to the beach and only short distance from BLM Beach, Karnaval Park, and Laura Shopping Center. Also nearby are Shemall Shopping Center and Terra City Shopping Center.
Hotel Features
Catch some rays on The Marmara Antalya's private beach, pamper yourself at the full-service spa, or spend the day at a marina.
Room Amenities
LCD televisions come with cable channels. Guestrooms also feature complimentary wireless Internet access, complimentary high-speed (wired) Internet access, and sofa beds.Information missing or incorrect? Tell us!
The Marmara Antalya
At your hotel
Unwind on the hotel's private beach. Lie back and work on your tan with relaxing beach amenities like umbrellas and sun loungers. Pamper yourself with a treatment at the full-service spa and enjoy amenities at The Marmara Antalya like a marina and an outdoor pool.
A complimentary breakfast is offered. The hotel offers a restaurant. Guests can unwind with a drink at one of the hotel's bars, which include a poolside bar and a bar/lounge. A computer station is located on site and high-speed wired and wireless Internet access is complimentary. This luxury hotel also offers a children's pool, a health club, and a steam room. Onsite valet parking is complimentary.
The Marmara Antalya is a smoke-free property.
- Private beach nearby
- Outdoor pool
- Poolside bar
- Children's pool
- Spa treatment room(s)
- Steam room
- Sauna
- Free breakfast
- Complimentary newspapers in lobby
- Babysitting or childcare (surcharge)
- Nightclub
- Bar/lounge
- Restaurant
- Room service (24 hours)
- 24-hour front desk
- Porter/bellhop
- Total number of rooms - 232
- Multilingual staff
- Number of floors - 21
- Hair salon
- Dry cleaning/laundry service
- Library
- Barbecue grill(s)
- Coffee/tea in lobby
- Concierge services
- Conference space
- Express check-out
- Full-service spa
- Gift shops or newsstand
- Beach/pool umbrellas
- Billiards or pool table
- Tours/ticket assistance
- Free Wi-Fi
- Free wired high-speed Internet
- Turkish bath/Hammam
- Elevator/lift
- Garden
- Health club
- Express check-in
- Luggage storage
- Meeting rooms
- Free valet parking
- Number of meeting rooms - 5
- 24-hour business center
- Conference center
- Direct access to private beach
- Beach umbrellas
- Beach sun loungers
- Pool sun loungers
- Beach towels
- Free self parking
- Number of buildings/towers - 2
- Airport transportation (surcharge)
- Television in lobby
- Wedding services
Stay connected
Available in all rooms: Free Wi-Fi , Free wired high-speed Internet
Available in some public areas: Free Wi-Fi , Free wired high-speed Internet
Park your car
Free self parking, Free valet parking
In your room
- Air conditioning
- Blackout drapes/curtains
- Complimentary bottled water
- Minibar
- Coffee/tea maker
- Daily housekeeping
- Private bathroom
- Hair dryer
- Shower/tub combination
- Cable TV service
- In-room safe
- Desk
- Iron/ironing board (on request)
- Sofa bed
- Rollaway/extra beds available
- Complimentary newspaper
- In-room massage available
- Pillow menu
- Cribs/infant beds (complimentary)
- Sofa bed size
- Free Wi-Fi
- Free wired high-speed Internet
Eat and drink
A complimentary breakfast is offered.
The Marmara Antalya has a restaurant serving breakfast only.
24-hour room service is available.
A marina and a health club are featured at the hotel. An outdoor pool and a children's pool are on site. Other recreational amenities include a sauna and a steam room.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Sailing nearby
- Scuba diving nearby
- Rafting nearby
- Scooter/moped rentals nearby
- Bicycle rentals nearby
- Parasailing nearby
- Aerobics on site
- Windsurfing on site
The Marmara Spa has massage/treatment rooms. Services include massages, facials, and body treatments. The spa is equipped with a sauna and Turkish bath/hammam. A variety of treatment therapies are provided, including aromatherapy, Ayurvedic, and hydrotherapy.
- Steam room in spa
- Thai massage
- Sports massage
- Number of treatment rooms 7
- Couples treatment rooms
- Manicures and pedicures
- Aromatherapy treatments
- Hydrotherapy treatments
- Ayurvedic treatments
- Massages
- Body treatments
- Facial treatments
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
- In-room accessibility
- Accessible bathroom
- Accessible path of travel
The fine print for The Marmara Antalya
When you arrive
Check-in time starts at 2 PM
When you leave
Check-out time is noon
How you can pay
Accepted at this hotel: American Express, Diners Club, MasterCard, Visa
Your pets
Pets allowed
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- Airport shuttle fee: TRY 140 per vehicle (one way)
- Late check-out fee: TRY 140
We should mention
This property offers transfers from the airport (surcharges may apply). Guests must contact the property with arrival details before travel, using the contact information on the booking confirmation.


text:
All four candidates in the race for EBR Parish Mayor-President have agreed to take part in a live debate sponsored by WAFB.
The event will be held at LSU's Manship School of Mass Communication. It will air live on WBXH-TV (Cable Channel 16) on October 30, 2012 from 7 p.m. until 8 p.m. WAFB/WBXH Anchor Andre Moreau' will moderate the debate with candidates fielding questions from four panelists. Panelists will include Greg Meriwether of WAFB-TV, Matt Kennedy of TALK 107.3, Stephanie Riegel of the Baton Rouge Business Report, and a representative from LSU Student Media.
Copyright 2012 WAFB. All rights reserved.
844 Government
Baton Rouge, LA 70802
(225) 383-9999
EEO Report
Closed Captioning
WAFB FCC Public File
WBXH FCC Public File


text:
I really like this shoe, outstanding in every area. One should note this shoe has a wide toe box, so if you don't need that it not the right shoe for you. First pair of Babolat's and I really like the style.
Fit right away, very light
Los tenis me quedan como guante, muy suaves y de gran durabilidad, para el frontenis es indispensable el agarre en la superficie ya que es definitivo para establecer un buen punto.
I have a terrible time finding any type of shoe that fits comfortably. My foot needs a wide toe box and my arches are very flat. These Babolat tennis shoes fit awesome right from day one. I played for three hours the first day with not one issue. I found them to be extremely comfortable, gave me tons of support and kept my feet relatively cool even in the Florida sun. They do get a bit slippery when the court gets wet but these are definitely the best court shoes I have ever bought. The construction looks like they will stand up to some regged use and I highly recommend them.
When it comes to shoes, boots, every day type of sneakers and tennis shoes I'm hard to fit... These Babolat V-Pro are the most comfortable tennis shoe I've ever slipped on my feet. From right out of the box they felt PERFECT!!! Once on the court the proved their worth immediately!!! Starts, stops... change of direction the V-Pro's never missed a beat. I'm going to order another pair or two before they're either sold out or Babolat changes the design!!! Highest recommendation from me... You will not be disappointed...


text:
Chun to Receive Lin Emerging Filmmaker AwardPosted in Press Releases on 10/10/2009 02:56 am by admin
WASHINGTON, D.C. – In conjunction with the 10th anniversary of its festival, D.C. Asian Pacific American Film announced that filmmaker Tze Chun has been selected the award recipient of the first ever George C. Lin Emerging Filmmaker Award in recognition of his feature length film, Children of Invention. The film is a timely narrative of economic and family hardship about two children forced to fend for themselves when their mother gets embroiled in a pyramid scheme and disappears. The award recognizes the director for his talent and exemplary commitment to filmmaking within the Asian and Asian American media & arts genre. Read the rest of this entry »


text:
The Mets participated in the first-ever MLB draft on this date in 1965 and wound up taking a Hall of Famer.
With major league ballplayer-turned-financial wizard Lenny Dykstra's financial woes making news recently, the sight of a Rolls-Royce owned by Dykstra seemingly being repossessed might seem like...
Based on his facial features this was pre-steroids. With the recession continuing to ravage the nation, there's been a lot of discussion...
It's Lenny Dykstra's birthday and it's the big 5-0 for Nails.
The 1994 Rotisserie Rule Book offers a view of two sports caught in amber--fantasy baseball and the real kind
Former New York Mets OF Lenny Dykstra is facing four years in prison after changing his plea from guilty to no contest on auto theft and providing a false financial statement in connection with...
Just like when I was nine years old, I still can't get enough of this guy: "I address the people of the great City of New York: You need to buckle your seat belts, because what you are about to read could not be made up. What I have somehow lived through the past 2½ years, and continue to live through now, makes me fully understand that God would never make someone endure what I have endured unless there was a reason for it. That being said, I was wrong when I thought God put me on this earth to entertain people at Shea Stadium. (Remember? I was pretty good at that.) However, I have come to realize that God put me on this earth to help people, to be a factor. And that, my friends, is what I intend to do — because at the end of the day, it's all about results. The kind of results I will bring to the party will be unlike any seen before. Talk is cheap; I am about walking the talk. You need to know, now that the "shock factor" and the disbelief of what these people did to me has worn off. What I am forced to endure with the FBI and the US attorney sets the stage for me to tell my side of the story, so that all of America will finally hear the truth surrounding my particular set of circumstances over the last two years. This is exactly the platform needed for me to get my story out, to get the real truth out. Bottom line: When all of the evidence is brought forward, the jury will be told by the judge to make an example out of these corrupt people so this does not continue to happen to other Americans. THE TRUTH, NOTHING BUT THE TRUTH, SO HELP ME GOD: To begin with, I had $100 million in assets when I filed my Chapter 11. It is also important for you to know that I did not get stupid overnight. I didn't make bad investments; every company that I have ever created or owned was and still is a winning company. And I sure as hell was not going to get on my knees, put my hands behind my head, and let this corrupt group of people masquerading as attorneys execute me — as that is what bankruptcy is all about. Just because they do this to everyone else does not mean I was going to let them do it to me. The corrupt world of bankruptcy is best described as "the death chamber." The so-called "grand theft auto" was never even brought; the case was dismissed. The theft was committed by them, as they stole a car I was leasing from Ford. Heck, it was only a Ford Flex. Are they allowed to steal it when they brought no charges? Are they allowed to shuffle me from jail to jail in what was left of my street clothes that they made me wear for seven days without even being permitted to take a shower? Are they allowed to then lock me up in a cell at three different courthouses, on three different days, and not even let me see a judge? Are they allowed to physically and mentally assault me and tie me up like I was some kind of animal "because they thought it was funny?" Are they allowed to torture me to the point where two nurses happened to be walking by and saw me — came to my rescue — took my blood pressure and registered it at 180 over 120? I told them, "If you are trying to kill me, then you better put a bullet in my head because I am not backing down. Torture me all you want, I am stronger than you will ever know." So, they kept going, almost like the movies, except this was a real, living nightmare! Over the last two years, they have basically stolen everything from me — my family, my kids, my homes, my cars, my businesses, my reputation, my money, my life. But what they can never steal is my HEART and my FIGHT — and at the end of the day, I will win and I will win big!"
Happy birthday, Nails.
Summary and audio of Lenny Dykstra on WIP in Philly talking about what an eff-up he is.
As part of the new SB Nation launch, prior users will need to choose a permanent username, along with a new password.
Your username will be used to login to SB Nation going forward.
Please login to your Vox Media account. This account will be linked to your previously existing Eater account.
As part of the new SB Nation launch, prior MT authors will need to choose a new username and password.
Your username will be used to login to SB Nation going forward.
We'll email you a reset link.
If you signed up using a 3rd party account like Facebook or Twitter, please login with it instead.
You must be a member of Amazin' Avenue to participate.
We have our own Community Guidelines at Amazin' Avenue. You should read them.
You must be a member of Amazin' Avenue to participate.
We have our own Community Guidelines at Amazin' Avenue. You should read them.
Choose an available username to complete sign up.
In order to provide our users with a better overall experience, we ask for more information from Facebook when using it to login so that we can learn more about our audience and provide you with the best possible experience. We do not store specific user data and the sharing of it is not required to login with Facebook.


text:
Scott County deputies raided a house near Long Grove, Iowa where they say they found a cache of weapons and ammunition and feared there may also be pipe bombs.
On Thursday, October 17, 2013, after an anonymous tip, probation officers went to inspect the home of a convicted felon, and asked deputies to join them. According to Lt. Bryce Schmidt with the Scott County Sheriff's Department, officers saw a rifle in the bedroom in plain site. At that point, they filed for a search warrant.
In the meantime, officers noticed some PVC piping in the garage. Schmidt says the pipes looked suspicious because they had caps on each end, similar to a pipe bomb. That's when they called in the bomb squad and a special robot detonated the pipes. At this time, Schmidt says it doesn't appear there were any bomb materials.
When officers searched the home, they seized close to a dozen weapons of various types including rifles, shotguns and handguns. They also seized boxes of ammunition. Schmidt says there were probably enough boxes to fill the bed of a pick up truck. Ammunition reloading equipment was also seized from the home.
Authorities arrested 40-year-old Christopher Bozik on a charge of possession of firearms as a felon. The Department of Correctional Services is looking into probation violations.


text:
What is the difference between defect, and bug?
That is: A defect does not necessarily mean there is a bug in the code, it could be a function that was not implemented but defined in the requirements of the software.
From the Wikipedia page on software testing:
There some different terms related to software bugs. Excerpt from a course I took:
According to this, there is no difference between a defect and a bug. However, some people argue that bug is an error that is found before releasing the software, whereas defect is one found by the customer.
I couldn't resist posting the famous "first actual case of bug being found".
Defect is an older ubiquitous term related to blemishes in materials of any type of goods.
Bug is a recent term related to programming to denote an immaterial blemish in a computer program.
Quoting Ilene Burnstein from the book Practical Software Testing (recommended) who parts from the definition in the "IEEE Standards Collection for Software Engineering" (1994) and "IEEE Standard Glossary of Software Engineering Terminology" (standard 610.12, 1990):
Faults (Defects)
You can read the full chapter in Google Books, here.
Oh dear.
Back in the old days - defective operation of a computer was caused by all sorts of things - including rats chewing the wiring and real bugs (critters) getting into the works.
The term BUG has stuck as a term that means something not working as expected.
BUG should be thought of as a jargon term meaning a defect.
A defect is a technically correct term meaning that the thing does not do as it should.
Wherever possible, using DEFECT instead of BUG actually carries with it a connotation that we acknowledge our failures (our defects, our lack of understanding of user requirements or the things we overlooked in implementation) instead of dressing it up as the more trivial sounding "bug".
Use DEFECT.
Try not to use the term BUG. Its silly, irrelevant, historical, and trivialising.
The difference is that the term "bug" sound magical. As if a program can randomly have bugs in it after you're done programming. If it has random bugs then it means you didn't conform to the specifications and your program is in error.
A defect means an error where the program doesn't conform to the specifications. This is more severe and basically says, any error is a huge problem with the program and this means that the program is not fit to be released.
The difference is in the attitude of the programmers who use the terms. There are millions of programs that are released with bugs and people are fine with that because they accept for some reason that a bug is magical and random and that every program contains at least one bug. However, a programmer who uses the term "defect" may become uncomfortable with releasing a program with a defect because the term implies a greater severity.
The implications of preferring one term over the other affect us daily.
From the IEEE Standard Glossary of Software Engineering Terminology, which is cited in the Software Engineering Body of Knowledge KA for Software Testing and Software Quality:
I think the definition of failure is the most relevant. Everything begins with a mistake, whether it's in the requirements, the design, the implementation, or the test case/procedure. If this mistake is manifested in software, it becomes a fault. A failure is caused by the existence of one or more faults in software.
I'm not to keen on the formal definition of error, though. I very much prefer the definition provided by dukeofgaming in his answer, however, the one in this answer is the IEEE standard definition of error.
According to Dependability: basic concepts and terminology:
I understand defect as just another name for fault.
Bug is confusing and can represent a fault or a failure depending on the context.
Note that there is no mention of specification: even a spec can be faulty.
Dan McGrath's answer nailed it right.
Maybe an example would make it clearer.
Example: Client wanted the web form to be able to save and close the window.
Scenario #1: Web form have a save button, and another close button. Result: Defect, because client wanted the 1 button to save and close the window. Developer misunderstood and created separately. Because both buttons performed their requirements, it is not a bug, but a defect because it didn't meet client's requirement.
Scenario #2: Web form have a save & close button, but only saves but does not close. Result: Bug. Because the button does not perform as required/expected. Developer knows it is suppose to produce that result but ultimately it didn't. (perhaps coding error)
Not sure if this makes it clearer.
p/s: from a developer stand point (I was once), both defects and bugs are just as important. We'll still fix it.
We even encountered weird anomalies, which we categorized under bugs and we continously try to figure out what is the cause and how to fix it. Terming it bugs doesn't make it trivial compared to defects.
I believe both are the same and can be used interchangeably. Both defects or bugs are written up by the tester (QA) and assigned to the developers to look at. The developer determines what caused the defect or bug and fixes it as the case may be. The tester retests the defect or bug and verifies that it performs as it should. I am a tester and when my expected result is not what I see, then I say rather gleefully that I have found a bug and I write up a defect for it, the bug gets fixed and I retest to make sure that the bug is gone and I close the defect.
protected by gnat Apr 2 at 19:35
Thank you for your interest in this question.
Because it has attracted low-quality answers, posting an answer now requires 10 reputation on this site.
Would you like to answer one of these unanswered questions instead?


text:
Tinnitus Treatment – Information and Remedies
Contrary to popular belief tinnitus is not actually a disease, but rather a symptom that can be caused by many different issues. This problem affects one in three people and no doubt you and everyone you know has experienced tinnitus in one form or another. Most often tinnitus is described as a ringing or a sound in the ears or the head, but there is no external source for the noise. If you have ever had a ringing in your ears for a few seconds that is tinnitus and some people will get these shifts in hearing for short bursts or randomly, while others can have a constant ringing in their ears, which makes it difficult to hear what is actually going on around them. People who are dealing with the symptom of tinnitus describe it as a ringing in either the ears or the head. It is often described as a high pitched whine or humming. Some people have described it as a ticking or clicking sound, as if crickets were in the ears. And still others, experience it as a roaring or rushing sound, like high winds or waves the ocean would make. Some sufferers only get this feeling occasionally, while other experience it all of the time. People who have temporary tinnitus symptoms often discover that the problem was caused from a simple infection, allergies, or even wax build up in the ears. This can be from a side effect in medication or another simple issue. For tinnitus connected to these simpler issues there is usually little that needs to be done. They are often just temporary problems and will often abate on their own or with a simple medication treatment. Tinnitus can also be connected to hearing loss that either comes with age or from damage to the ears from noise pollution and this isn稚 as easily treatable. When connect to hearing loss, people dealing with tinnitus are often unable to hear actual noises accurately. Because of the constant noise in their ears and inability to hear what is going on around them, many people with tinnitus also suffer from depression. Research is starting to uncover neural issues in connection to hearing loss and tinnitus. There have been studies which have shown that people with tinnitus actually have damage to their receptor cells in the brain and there is a slight disconnect from the hearing process to the brain receptors. Because of these studies it is now believed that tinnitus is actually a symptom of two different issues. The first is from problems with the inner ear or the acoustic nerve. This is referred to as otic tinnitus. The second is cause from disorder outside of the ear, but still within the head. This is referred to as somatic tinnitus. Recently there has been evidence of a third possibility and that is tinnitus due to a misfiring of the nerves between the head, neck, and brain. Whatever the causes there are things that can be done about it.
Tinnitus Treatment
It's good to know what the underlying causes of your tinnitus are before seeking out treatment. Certain treatments will be more effective for specific disorders. There are some simple, yet, effective things that you can do to treat your tinnitus, or at least find relief. One thing that is recommended for people with tinnitus is to avoid loud places or completely silent places. Both noise and silence can cause the symptoms of tinnitus to worsen. It is also suggested that people dealing with tinnitus avoid overuse of electronics and cell phones. Unfortunately, these treatment options are not always possible. Many also recommend making changes to daily routines, like food intake in exercise. Foods that are high in salt or full of preservatives have proven to increase tinnitus issues. If you want to lessen the ringing, it is a good idea to avoid overuse of alcohol, caffeine, and smoking. Anything you put into your body that will affect blood flow can affect the tinnitus. Caffeine has actually proven to be a potential cause of tinnitus. Caffeine can increase blood flow, but it also shifts brain patterns and can interfere with drugs or other tinnitus treatments. Stress can also be a contributing factor. If you notice your tinnitus flares up during times of high stress learning to cope with stress might be your best treatment option. There are many ways to lessen the effects of stress, including meditation, yoga, therapy, and conscious breathing. There are also several natural remedies to tinnitus. Some of these come with active ingredients that have proven to help blood flow, increase nerve connectivity, and stop the ringing forever. Because these products are natural there are none of the side effects that you would experience from taking prescription drugs.
Tinnitus Remedies
One of these natural remedies comes from periwinkle and it is called Vinpocetine. It is proven to increase the blood flow in the brain and has been used for memory loss treatment for many ears. Because of the increased blood flow to the ears this lessons the ringing that so often comes with tinnitus. Choline Bitartrate is another natural substance that can help with tinnitus. This nutrient helps the cell membranes function properly. Sound travels through cell membranes and when they are functioning properly the overall process of the ear works better. These are just two of the many natural substances that can help with hearing loss and ringing. When it comes to tinnitus treatment if you can take many of these items in combination, and find the right combination for your specific issues, you could find that your tinnitus goes away for good. Using a combination medication and taking other health steps with your diet and exercise you can stop the ringing and improve your overall hearing. The best way to improve hearing and stop tinnitus is to improve brain circulation and optimize the neural pathways. Itç—´ also important to make sure, at the same time, that you are getting the best nutrients that are essential to helping hearing and decreasing damage. Reference: http://thehearingfix.com/tinnitus-treatments/


text:
Framingham's Tom Tierney is the Republican selection for the Massachusetts 5th district seat in Congress, the AP reports.
Tierney, a 69-year-old actuary consultant, topped fellow Republicans Frank Addivinola of Malden and Jeff Semon of Lexington. He will face incumbent Ed Markey, who has served 18 straight terms in Washington, in the general election in November.
According to the AP, Tierney received 42 percent of the vote, Addivinola placed second with 31 percent and Semon received 28 percent. A total of 11,539 ballots were cast in fifth district primary.
Tierney previously ran for in Congress in 2010, losing in the Republican primary to Gerry Dembrowski in the primary. Dembroski went on to lose to Markey.
An official from Tierney's camp previously said they felt poised going into Thursday's vote.
"We feel pretty confident going into the primary as we have been out and about putting up nearly 200 signs and meeting the voters of the 5th District," Phillip Petros said in an email before Thursday's vote.


text:
We had my grandaughter's birthday party by our front yard pond. One of her gifts was a new sand box which made a great place to relax and watch the older kids swim.
Chillin' At The Beach
By: ban101Subscribe Channel: Weather Location: Huntington, IN
+ Comment!
This story is inappropriate and should be flagged for moderation. Please choose from one of the following options:


text:
Jagex Ltd, a World leading independent Online Games Studio, is looking for a highly motivated and enthusiastic Senior Editor to edit video content efficiently, professionally and to tight deadlines.
This unique and highly rewarding role will allow for a great deal of creative freedom, and the successful candidate will be expected to work alone as well as closely with the rest of the video production team helping to define our promotional strategy through videos that are exciting and informative. The Senior Editor also supports and guides other Editors in the team. The successful candidate will be a self-starting and self-assured individual with a passion for gaming.
Key Duties Include:
Essential Requirements:
Desirable Requirements:


text:
Town Square
PUSD step/contract increases no different than AIG bonuses!
Original post made by Parent on Mar 21, 2009
on Mar 21, 2009 at 2:07 pm
Wake up and smell the roses. The AIG bonuses should not be compared to teacher salaries. However the AIG bonuses can be compared to the top administrators long term retirement bonuses. Come on PUSD board do something that helps the kids. You can restructure the contracts of the top administrators, so that they do not get these very expensive bonuses. Lifetime helath insurance for the four top administrators and spouses plus a cash bonus of 40K each, these don't even include the other monies that Dr. Casey gets. Why should the tax payers pass a parcel tax that would indirectly pay for these bonues. Yes, we know that none of the parcel tax money goes to administrators, however if you have parcel tax funds, then that frees up money within the districts budget to go to the administrator's bonuses.
on Mar 21, 2009 at 4:03 pm
I agree that they parallel one another. The AIG retention bonuses were a known contractual agreement. The step salary increases are similar in nature - a contractual agreement. In both cases taxpayer money is being requested and will ultimately (whether directly or indirectly) pay for those increases. The Pleasanton community should be no less outraged over the step salary increases this year as they are about the AIG retention bonuses. Instead of following the same path that Congress took and providing tax payer dollars without requesting a renegotiation of those contracts, the Pleasanton community should force the PUSD board to negotiate that salaries be frozen at their current rates for at least one year until the financial outlook can be re-evaluated. I'm not proposing salary reductions, just a freeze on increases. If the district has as good of a working relationship with the employee units as they claim on the PUSD webpage, this discussion shouldn't be one that is difficult to have. I applaud the board members for recognizing the importance of maintaining the quality level of education Pleasanton has established over the years. I want to support the tax, but not if the administration and educators aren't willing to show their consideration to the community by foregoing their increases for the upcoming year. The Pleasanton community should be dictating to the board the conditions upon which we are willing to provide additional tax dollars, not the other way around.
Oh, and maybe John can pay back a little more of that interest free $200,000 loan he got as a measure of good faith. I'm pretty sure he can swing it with his annual tax free $10k annuity and $227k annual salary.
on Mar 21, 2009 at 4:10 pm
Peter Del Prado is right on. Monies from a parcel tax frees-up other monies. Budget games, budget games, budget games and the PUSD should've,could've, but they didn't and they won't. They took the easy way out and went to the Bank of the Taxpayer to see if the ATM still has some cash in it.
I saw budget games in the corporate world daily, but they didn't impact taxpayers...this does and it shouldn't. Public pensions at the state, county, and municipal levels are killing CA and the reluctance of govenrment agencies whether they are PUSD or some other agency are going to bring harsh reality to us all.


text:
With an investment of more than $200,000, Miami-Dade County began installing a lighting system at Westbrook Park in Westchester on Saturday, after neighbors complained that the place was being used for drug dealing.
The director of the county's parks and recreation department, Jack Kardys, said the project includes the installation of 61 light posts powered by solar panels.
"This is about a solar-energy efficiency project that will illuminate the pedestrian circuit of the park," said Kardys shortly before the public event on Saturday morning, attended by about 20 neighbors.
County Commissioner Javier Souto, who attended the event, highlighted Kardys' role in finding a quick solution to the neighbors' complaints.
In November, the neighbors said that the park located at 1325 SW 103rd Pl., which had no lights, had turned into a place of suspicious transactions.
Nancy Gómez, a neighbor who has lived next to the park for 34 years, congratulated the authorities for listening to the community and launching a project that will contribute to the area's security.
"The illumination of the park is a very good project," Gómez said. "There was too much movement of cars here with very weird people doing strange things. With these new lights it will be a little more difficult for that to continue."
María Rodríguez, another neighbor, said that the "community was looking forward" to the new lighting system.
"The park was remodeled about five years ago, and what was needed was lighting," Rodríguez said. "The vandals are always ruining the atmosphere, and we believe that with the public illumination we will be safer."
Kardys said that Westbrook is one of 260 parks owned by the county. It has a children's playground and about 1,200 feet of pedestrian paths on its 2.5 acres.


text:
June 5, 2014 - CDC Posts Investigation Notice regarding human Salmonella Typhimurium Infections Linked to Exposure to Clinical and Teaching Microbiology Laboratories
October 14, 2011 - CDC Proposed Rule Changes for Importation of Etiologic Agents
The CDC published a Notice of proposed rulemaking in the October 14 Federal Register to revise regulations that cover the importation of etiological agents, hosts and vectors. The rule proposes changes to the Foreign Quarantine regulations, including section heading, terms and definitions (eg,"host", "vector"); a requirement for appropriate biosafety measures as a prerequisite for a permit and a provision for CDC inspection authority to inspect an applicant's facility for the conduct of research at the biosafety levels 3 and 4 if it has not been inspected by the select agent program; permit exemptions are described for select agents, diagnostic specimens, genomic material, and regulated products. The importer must be in compliance with all applicable laws concerning the packaging and shipment of infectious substances.
June 21, 2011 - ASM Participates in Conference on Emerging Technologies and Institutional Biosafety Committees
The NIH Office of Biotechnology Activities (NIH OBA) invited ASM to participate in and serve on the planning committee for their recent biennial conference that focused on biosafety issues and Institutional Biosafety Committee (IBC) oversight of laboratory research involving emerging technologies. The conference was intended to increase understanding of biosafety and biosecurity issues surrounding advances in select agent research, synthetic biology, nanotechnology, and the implications for institutional biosafety programs including IBCs. Presentations and panel discussions outlined strategies and resources for addressing program gaps, strengthening IBC risk assessment s for emerging technologies, developing comprehensive training programs, raising biosecurity awareness, and aspects of personnel reliability programs. The program was targeted towards IBC members and staff, biosafety professionals, research administrators, scientists, regulators and others involved in the conduct and oversight of research. Approximately 200 people attended the June 12-14 conference in San Diego. Claudia Mickelson, Ph.D., a member of the PSAB's Committee on Biomedical Research represented ASM at the conference.
May 11, 2011 - MMWR Special Supplement: Guidelines for Biosafety Laboratory Competency CDC and the Association of Public Health Laboratories
These guidelines for biosafety laboratory competency outline the essential skills, knowledge, and abilities required for working with biologic agents at the three highest biosafety levels (BSLs) (levels 2, 3, and 4). The competencies are tiered to a worker's experience at three levels: entry level, midlevel (experienced), and senior level (supervisory or managerial positions). These guidelines are intended for laboratorians working with hazardous biologic agents, obtained from either samples or specimens that are maintained and manipulated in clinical, environmental, public health, academic, and research laboratories.
August 13, 2010 – ASM Submits Comments to CDC on Draft Guidelines for Safe Work Practices in Human and Animal Clinical Diagnostic Laboratories
On August 13, the PSAB Committee on Laboratory Practices submitted comments to the Centers for Disease Control and Prevention on its draft Guidelines for Safe Work Practices in Human and Animal Clinical Diagnostic Laboratories.
May 3, 2005 - The CDC has posted an Interim CDC-NIH Recommendation for Raising the Biosafety Level for Laboratory Work Involving Noncontemporary Human Influenza (H2N2) Viruses. The recommendation is excerpted from the draft Biosafety in Microbiological and Biomedical Laboratories, 5th edition.
CDC-NIH Recommendation
For More Information


text:
Funding opportunities
Development of methods for gene targeting in human ES cells
Funding Type:
Tools and Technologies I
Grant Number:
Funds requested:
$799 358
Funding Recommendations:
Not recommended
Grant approved:
Public Abstract:
Gene targeting refers to the practice of introducing genetic modifications to cells with the goal to inactivate a specific gene or alter its biochemical properties. Over the last twenty years, this has been a major approach that investigators use to delineate in vivo function of genes in the mouse, the mammalian genetic model organism. Unfortunately, gene targeting technologies for human ES cells are still immature. Here we propose to develop and optimize the method for gene targeting in several widely used human ES cell lines. We will compare a conventional method routinely used for gene targeting in mouse ES cells and an recombinant Adeno-Associated Virus (rAAV)-based method that is increasingly being used for gene targeting in human somatic cell but not yet in human ES cells. We will first compare the time requirement, experimental complexity and efficiency of these two methods in knocking out one test gene in five human ES cell lines. We will experiment with various parameters in an attempt to optimize stable transfection and gene targeting frequency across different human ES cell lines. Once we identify the best protocol for gene targeting, we will apply the method to targeting of eight genes in human ES cells, to determine the robustness and generality of our gene targeting method. Successful completion of this project will lead to a robust and generally applicable gene targeting method for human ES cells. Such a tool will be critical for understanding the functional roles of various genes in ES cell proliferation and differentiation. It will also greatly facilitate the development of ES cell based therapeutics by, for example, enabling the repairing of faulty genes in patient specific ES cells or induced pluripotent stem (iPS) cells.
Statement of Benefit to California:
The overall aim of this application is to develop a robust and generally applicable gene targeting method for use in human ES cells. Development of such technology is highly significant if we are to achieve the full potential of human ES cells as a tool for both therapeutic development and basic research. It will enable the repairing of faulty genes in patient specific ES cells or induced pluripotent stem (iPS) cells, thereby speeding up the development of ES cell based therapeutic strategies. Further, the ability to inactivate or modify gene function in human ES cells will permit scientists to define roles of genes in self-renewal or differentiation of these cells, which is crucial for a clear understanding of the ES cell biology and ultimately developing better diagnostics and therapeutic tools.
Review Summary:
In aim 1, this proposal seeks to improve the efficiency of homologous recombination in human embryonic stem cells (hESCs) by comparing a conventional electroporation approach with the use of adeno-associated virus (AAV)-mediated DNA delivery. The investigators will also examine the effects of homology arm length and of isogenic DNA on gene targeting frequency. In aim 2, the authors propose to use the optimum technique to target eight genes in hESC. They will add a tag that can be used for immunoprecipitation to four transcription factors, and they will place a fluorescent marker into the genomic location of four genes that are expressed during corticospinal or serotonergic development. Reviewers were moderately enthusiastic about this grant. The goals of the grant were considered important, the project was well-designed, and the principal investigator (PI) and main collaborator were described as strong. However, reviewers' enthusiasm was curbed as the work seemed overly ambitious for a two-year grant, and there were concerns about the lack of commitment of the main collaborator. Reviewers expressed different opinions about the potential impact of the first aim of this proposal. All reviewers agreed that the AAV method was potentially exciting. However, some reviewers commented that the validation and comparison of the two methods for homologous recombination would be very important, whereas others felt that it was irrelevant. Furthermore, although one reviewer felt that the choice of targeted locus during the optimization studies was clever, others pointed out that a similar approach is being pursued by others. With regard to aim 2, reviewers commented that the cell lines generated would be valuable tools. The tagged transcription factors would greatly facilitate chromatin immunoprecipitation experiments and genome wide analysis of genetic regulatory networks - work that would clearly fall directly into the core interests of the PI's laboratory. The reporter gene work would also generate a series of very useful reagents that could be utilized by the wider research community for studying hESC differentiation to neuronal cell types. However, the reviewers questioned the rationale for including the two disparate goals of aims 1 and 2 in the same application, especially given the amount of work involved in each one. Individual experiments were judged to be feasible, but the overall plan was considered too ambitious for a two-year grant. The first aim, to optimize homologous recombination in hESCs, received several minor criticisms. The rationale for committing resources to further optimize the gene targeting frequency using conventional methods (Aim 1a) was questioned, as one reviewer commented that the work had already been published by others. Investigating the use of AAV was considered more interesting. In terms of the preliminary data, reviewers were concerned that the description of the HUES9 clones containing targeting events at the specific locus the PI is studying did not involve karyotyping. As maintenance of a normal karyotype is likely to be considered an important feature of genetically modified hESCs, it would have been prudent to initiate these studies with lines that afforded this possibility. The preliminary data provided to support the second aim is sufficient to suggest that the applicants would eventually be able to generate the reagents that have been listed. However, the overall volume of proposed gene targeting experiments is large and there is good reason to think that only a fraction of the reagents would be generated within the time frame of the grant. Reviewers commented that the application might have fared better if only one of these projects had been proposed. The PI has strong experience in technology and genome mapping, has an impressive publication track record in the areas of whole genome analysis of genetic regulatory networks. This includes senior authorship on a number of papers in high impact journals. The main collaborator is a well-trained and very promising young neuroscientist, and brings needed expertise with ESC genetic modifications to the project. A final collaborator provides AAV expertise. Reviewers expressed concern that neither collaborator committed any percent effort to this project. Overall, reviewers considered this proposal to be of high impact, but reviewers doubted whether the work described could be accomplished within two years.


text:
The eagerly awaited draft guidance on biosimilars* was finally issued by the FDA on February 9, 2012. It was drafted in the spirit of enlightened health care reform, with a view towards fiscal responsibility and. . . to annoy the nemesis of all that is good in health care, "Greedy Big Pharma."
Copyright © 2000-2012 Quadrant HealthCom Inc., Parsippany, NJ, USA. All rights reserved. Unauthorized use prohibited.
The information provided on FemalePatient.com is for educational purposes only.
Use of this Web site is subject to the medical disclaimer and privacy policy.


text:
The Ohio State University Extension in Geauga County will offer training from 1 to 4:30 p.m. Feb. 12 for all growers interested in obtaining a private pesticide applicators license.
The training will prepare people to take the certification test so they may obtain restricted use pesticides. Fee is $35, which includes the CORE manual, CORE workbook, handouts and refreshments.
Class will be held in the Extension Office located in the Patterson Center on the Geauga County Fairgrounds in Burton Township. For details and to register, call 440-834-4656.


text:
Professor Gerwig-Moore's teaching and scholarship interests center around constitutional criminal law, appellate and post-conviction practice and procedure, prisoners' rights, and other practical matters relating to serving the public interest.
Since coming to Mercer, she has created and now teaches The Habeas Project, the only pro bono effort in Georgia to focus on non-capital post-conviction cases. The clinic has briefed and argued dozens of cases—including cases of first impression in the state's highest court—and has won relief for nearly half of its imprisoned clients. In Alford v. State, Sarah and clinic students urged the retroactivity of Alabama v. Shelton and won relief for their client along with a "Case of the Year" Award from the Georgia Association of Criminal Defense Attorneys. The clinic has also helped establish sleep-walking defense in Georgia (Smith v. State) and helped make favorable law in a number of cases related to knowing and intelligent guilty pleas.
She is a regular panelist or speaker on issues of land use, economic development, and constitutional criminal law/appellate practice. She has been counsel of record or co-counsel in nearly 100 reported cases in the state and federal courts. Her articles and essays include Fresh Ears, Fresh Eyes: Final Editing Through Reading Aloud, 63 MERCER L. REV. 971(2012); Gideon's Vuvuzela: Reconciling the Sixth Amendment's Promises with the Doctrines of Forfeiture and Implicit Waiver of Counsel, 81 MISS. L.J. 439 (2011), and Saving Their Own Souls: How RLUIPA Failed to Deliver on its Promises, 4 LEGISLATION AND POLICY BRIEF Vol 4. Iss. 1, Article 4 (2012).
In her work in Mercer's Law and Public Service Program, Sarah remains engaged in public service within the law school and community. She is serving her second term (currently as Chair) with the Macon-Bibb County Planning & Zoning Commission. Sarah was also a founding Co-Chair College Hill Corridor Commission and founding member of the Steering Committee of the College Hill Alliance (www.collegehillmacon.com), which are both devoted to revitalizing Macon's historic first neighborhoods. Other past and current board service includes The Central Georgia Affiliate of Susan G. Komen for the Cure (Grants Chair), the State Bar Indigent Defense Committee, and the Ocmulgee National Park and Preserve Initiative. To contribute to the social growth and development of the community, Sarah also writes the "Time Outs" column for The 11th Hour, a weekly magazine published to highlight entertainment and arts in Macon.
In addition to the Habeas Project, Sarah also teaches the Public Defender Clinic, Public Interest Practicum I and II, Introduction to Client Counseling, Seminar in the Jurisprudence of Crimes, and Introduction to Law Study. She is a Justice of the Mercer Law School Honor Court, the chair of both the faculty Public Service and Student Affairs Committees, and advises the Association of Women Law Students.
Before joining the Mercer faculty, Sarah was the Senior Appellate Supervising Attorney at the Georgia Public Defender Standards Council (the central office of the statewide public defender system). She received her BA, summa cum laude, from Mercer University, her Master of Theological Studies from Emory University's Candler School of Theology, and her JD from Emory University School of Law. Honors and awards include the Myki Mobley Award to the Academic Excellence and Social Concern (2002); the Young Lawyers Division of the State Bar of Georgia "Commitment to Justice" Award (2006); a two-time winner of the Georgia Association of Criminal Defense Lawyers' Case of the Year Award (2006 and 2009); Emory Law School's Herman Dooyeweerd Prize in Law and Religion