text:
Installations Direct's roster of certified and professional service providers ensures proper installation for a variety of reputable brands of double basin sinks. Call their customer service line at 855-461-5761 with any questions regarding your order. Representatives are available 24 hours a day, 7 days a week to assist you.
When you order professional kitchen sink installation services for your kitchen sink from Installations Direct, the procedures included with your purchase are full circle.
With this sink installation service, included in the installation service is the sink, faucet and garbage disposal installations (when configuration is present).
Please note that this double basin sink installation is for a double basin drop in sink only. The old double basin sink being replaced must also be a double basin drop in sink and cannot be an undermount double basin sink.
Your service provider will:
Please be sure that the new double basin sink you order will fit in the same location of the old sink. The Service Provider will not be able to cut the counter top for your new double basin sink or perform cosmetic services, such as painting, wallpapering, or re-tiling. The faucet and garbage disposal to be installed must match up to the openings in the new sink. Any additional work outside the scope listed above will call for additional time and compensation for the service provider. Should the need for additional work arise in order to complete your installation in a safe and professional manner, Installations Direct will contact you. Installations Direct reserves the right to cancel and refund the entire installation service if no local service provider is available for your location.
To ensure a smooth, safe, and efficient installation process, be sure that:
Professional and Personable Service Providers
An Installations Direct certified service provider who works in your community will be providing the service for your order. All Installations Direct sink service providers are recruited from within the industry and have ample experience with sinks from a wide range of brands. Each Installations Direct service provider has full on-site support to ensure the best installation service possible. Installations Direct has a credentialing process that all service providers must fulfill. Applicants must register and provide proof they are insured, bonded, and licensed and must submit to a background check--requirements that guarantee your service provider has been fully vetted.
You will be contacted by an Installations Direct representative within one business day of your purchase to verify your order. The service provider assigned to your order will then contact you to schedule an appointment that is convenient for you (usually one to two days in advance). Weekend appointments are available. For any customer service related issues, call Installations Direct toll-free at 855-461-5761.
Cancellations and Refunds
To receive a full refund, the service order must be canceled at least 24 hours prior to the scheduled appointment time. Any cancellations with less than 24 hours' notice are subject to a site visit trip charge of $89.
About Installations Direct
Installations Direct streamlines the process of purchasing services directly from contractors. From installation, delivery, assembly, and other on-site services, Installations Direct uses a vast network of local service providers who are certified, licensed, and insured to work on your specific project need. Rest assured that your on-site service is completed professionally and correctly by allowing Installations Direct to do it for you. Whether it's providing consultations on home décor, installing major appliances and fixtures, or assembling furniture or equipment, Installations Direct's reliable team makes it convenient for you to purchase any number of services.
Double Basin Sink Install: | $365.00 |


text:
FOXBOROUGH — It started with the Patriots winning the coin toss and doing what they always do. It ended with Billy Cundiff doing something he almost never did.
The Patriots' 23-20 victory at Gillette Stadium in last year's AFC Championship game played out like most of the other meetings with the Ravens: close, emotional, a few big plays, plenty of hard hitting. The game on Jan. 22, 2012, just had a lot more at stake.
Sunday's rematch brings the same teams to the same stadium on the same weekend as a season ago. The prize to the winner is just as tantalizing: a trip to Super Bowl XLVII in New Orleans.
For the Patriots, they're playing for the eighth Super Bowl trip in franchise history, and might have history on their side. They're 4-0 in AFC Championship games played in Foxborough. The Ravens are seeking their second appearance in the Super Bowl, and quarterback Joe Flacco already has led his team to five road playoff wins, including one at Gillette Stadium. Baltimore beat the Patriots three years ago in the wild-card round, 33-14.
Last year's playoff contest was the first of three games the teams will have played against each other in less than a calendar year. One team — and the majority of the 68,756 in attendance — left the stadium last Jan. 22 elated. The other team left deflated, wondering if it would get another opportunity.
It has, just a year later, in eerily similar fashion.
"Everything it took to get to that championship game last year, and then being in that game and having it be such a great football game — an epic kind of a game — and then losing it in a way that was tough . . . It's tough to lose a game at the end like that," Ravens coach John Harbaugh said. "We have all the respect in the world for the Patriots. We play them a lot, and they're always tough battles. All the experiences that we've had against them help us going into this game."
Both teams this week have publicly minimized last year's game and its effect on the rematch, saying the rosters are different. Literally, that's true. But most of the key parts have remained.
Of the Patriots' 22 starters in last year's game, 17 are still in the regular playing rotation. The five who won't be in uniform: offensive linemen Matt Light (retired) and Brian Waters (didn't play this season), tight end Rob Gronkowski (injured), defensive end Mark Anderson (signed with Buffalo), and safety James Ihedigbo, who will be on the opposite sideline after signing with the Ravens in the offseason.
The Ravens still have 18 players of the 22 who started against the Patriots last season.
Starters don't always tell the full story, though. BenJarvus Green-Ellis (now with the Bengals) didn't start last year's game, but he was the Patriots' leading rusher, with 68 yards on 15 carries. He scored the Patriots' first of two touchdowns, on a 7-yard run in the second quarter that made the score 10-3.
Two Stephen Gostkowski field goals bookended Green-Ellis's touchdown and gave the Patriots a 13-10 halftime lead. But the Ravens took their first lead after another Gostkowski field goal, with Torrey Smith catching a 29-yard touchdown pass from Flacco for a 17-16 lead. They pushed the lead to 20-16 on a 39-yard Cundiff field goal in the final minute of the third quarter, setting the stage for a fourth quarter that would produce unexpected plays and players.
The Patriots began what turned out to be the winning drive immediately after falling behind, 20-16. The first play was notable because of how it ended, with Gronkowski's left leg getting pinned under the weight of tackler Bernard Pollard after a 23-yard gain. Gronkowski was forced to leave the game with a high ankle sprain, and was still hobbled two weeks later when the Patriots lost to the Giants in the Super Bowl.
The Patriots faced two third downs on the drive, but it was a fourth-down play that got them into the end zone and in front of the Ravens. Tom Brady went up-and-over, diving in from 1 yard to help push the Patriots ahead, 23-20.
After two interceptions (one by each team) and two other drives that fizzled, the Ravens took over at their 21-yard-line with 1:44 left, still trailing, 23-20.
Flacco completed five passes on the final drive, directing the Ravens to the Patriots' 14-yard line in seven plays, and well within Cundiff's range for a tying field goal, which seemed to be the best-case scenario at the time for the Patriots. But with 27 seconds and one timeout left, the Ravens weren't thinking about tying the game. They took two shots at the end zone.Continued...

subset: commoncrawl


text:
The former Strikeforce and K-1 Heavyweight champ has been a bit of a bust in the UFC. His manager was on the MMA Hour and talked about the Dutchman's new training camp in Thailand.
Peripatetic UFC Lightweight Melvin Guillard explains his latest training camp move to American Top Team was motivated by a disagreement over money with Colorado's Grudge Training Center.
UFC Lightweight Melvin Guillard tweeted that he was leaving Florida's Blackzillians camp after a 1-4 UFC run and returning to Greg Jackson's MMA in New Mexico but reports are coming out of that camp saying "not so fast Melvin."
After a 1-5 run with the Blackzillians, Guillard will be returning to his old home at Jackson's.
UFC Light Heavyweight contender Vitor Belfort will be challenging Jon Jones with an old mentor in his corner for the first time in over a decade.
The Blackzillians, training camp of UFC superstars Rashad Evans, Alistair Overeem and others has a new head coach as Mike Van Arsdale is out and Mario Sperry is in.
Rashad Evans talks about the Curse of the Blackzillians (via cagefanatic) Cage Fanatic went to the UFC on Fox 2 open work outs at the famous Chicago Boxing Club and talked to Rashad Evans about...
A behind the scenes look at Rashad Evans' camp leading up to his fight with Phil Davis.
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3070 Boundary Scan
Learn concepts of Boundary-Scan technology. TAP (test access port), the functionality of registers (BYPASS, boundary, IDCODE), and the structure of the "boundary-cell" are described.
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5DX Cooperative Maintenance Training, Part 2
Troubleshooting and repairing an Agilent 5DX in-house gets you back in production fast.
Classroom Training |
60 GHz Power Amplifier Design for Wireless HDMI
Originally broadcast Oct 13, 2009 - Access the .pdf file of the presentation
Webcast - recorded |
A Practical Approach to Verifying RFICs with Fast Mismatch Analysis
Originally broadcast October 28, 2010
Webcast - recorded |
ADS in 3D: Speed Your Design with Integrated 3D EM Simulation
Originally broadcast March 24, 2010
Webcast - recorded |
Advanced Passive Intermodulation (PIM) Measurement System Webcast
Original broadcast August 29, 2013
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Advanced Product Design & Test for High-Speed Digital Devices Webcast
Original broadcast Jan 18, 2012
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Agilent 3070 Board Test Double Feature Webcast
Originally broadcast Feb 24, 2011
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Agilent EEsof EDA Customer Education and Services
Brief overview of Agilent EEsof EDA Customer Education and Services.
Training Materials 2010-08-11 |
Agilent's Events for United Kingdom and Ireland
Welcome to Agilent's Upcoming Events Page for United Kingdom and Ireland
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Analyze Agile or Elusive Signals Using Real-time Measurement and Triggering Webcast
Original broadcast April 24, 2013
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Antenna Design Automation with Scripting and Parameterized EM Analysis Webcast
Original broadcast February 7, 2013
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Antenna Measurement Basics
Review the terminology, measurement types, errors sources and test considerations. Reprinted with the permission of Orbit/FR Inc.
Training Materials 2004-03-03 |
AOI Family User Maintenance Training
Gain an understanding of the hardware components that make up an AOI system. Learn to maintain and repair your Agilent AOI system.
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Assembled PCB Inspection: SJ Family - Archived Event and Seminar Material
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Automated Stimulus & Current Drain Analysis for Validating/Optimizing Mobile Device Run Time
customer viewable presentation
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Automating On-Wafer Measurements with the new Agilent IC-CAP WaferPro
Originally broadcast Jan 27, 2011
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Automating SPICE Library Validation
Recorded webcast and slide set for a Model Quality Assurance (MQA) webcast held on October 22, 2013.
Seminar Materials 2013-10-22 |
Back to Basics Part 2: Signal Generation
Original broadcast Feb 29, 2012
Webcast - recorded |
Basics of RF Amplifier Test With the Vector Network Analyzer
Original broadcast Mar 13, 2012
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Battery Run-time: Innovative Measurements / Greater Insights Webcast
Original broadcast April 30, 2013
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Boundary Scan for Testing On-Board DDRs Webcast
Original broadcast October 22, 2013
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Boundary Scan Online Training
Get up to speed on boundary scan! Access online training materials for boundary scan from the comfort of your desk!
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Boundary Scan Test Methods for DDR Memories
Originally broadcast May 18, 2010
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text: [postcard] [letterhead] USO insignia [letter] 30 April 1944 Mr. Dorsey, it seems that I have not time to write you a letter as I prommised, but the Air Corps are Crowding the basic training into 6 to 8 weeks now instead of the 12 to 14 weeks heretofore, and then we will be shipped somewhere else for what ever we are classified. But we will be somewhere in the Air Corps. excuse the card & writing as I have to rush on. More later Chas. Fisher


text:
By Mr. Smola of Palmer (by request), a petition (accompanied by bill, House, No. 3345) of George Hemingway for legislation to increase maximum labilities of annuity benefit insurance of the Massachusetts Life and Health Insurance Guaranty Association. Financial Services.
Sponsors: |
Todd M. Smola
(By Request)
Status: | Referred to Joint Committee on Financial Services |


text:
War-torn Syria sees restoration of Net after two-day outage
The Internet is back up in most parts of Syria, which had been experiencing what some say was a state-orchestrated outage presumably designed to hamper rebel forces.
The BBC reported today that the country's capital city of Damascus again had Net access, and Renesys, which operates a real-time grid that continuously monitors Internet routing data, said in a blog post today that it had confirmed a "largely complete restoration of the Syrian Internet."
Renesys and other companies that offer back-end Net services detected a sharp cutoff in traffic to Syria on Thursday. According to Reuters, Syria's minister of information blamed the outage on terrorists, … Read more


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text:
The Ashton Blouse
Item# 4224885
30% Off - Price reflects discount.
Excludes OPP Bracelets, B1G1 Free Suit Event, 50% Off Select Styles, Sale & Final Sale.
Color: $49.95 $34.96
An office-worthy basic in key colors, this drapey essential is a breezy option fit for mixing and matching!
- Drapey crepe
- Point collar with split-V button down
- Chest pocket
- Full sleeves with buttoned roll-tab
- Curved hem
- 100% Polyester
- Machine wash. Tumble dry.
- Imported
Free Return Shipping on Petite Sizes by mail
Beautiful Shirt
This is a great shirt. It's very relaxed and casual: perfect for when you want to feel comfortable while still looking great. I do think it runs a bit large. I purchased the xs so I wouldn't be swimming in extra fabric. Now I'm debating buying more colors......
March 5, 2014
Must have
I love this shirt, you can dress it up for a night out or wear to work! I bought this shirt in red, green, blue, and blush pink! I love them all! The only thing I wish were a little better are the sleeves, sometimes they come unbuttoned and it takes time to botton and roll up the sleeves. I am about 110 with a athletic build and the XS is perfect! Was a little scared to try the petites and order without trying on. Cant wait until petites are in the store!
March 3, 2014
A must have shirt!
Bought this in the coral color and it's gorgeous. Love the fit and the material is really soft. Ordered an XS which is my usual size and it fits great! Will probably order a couple more because this shirt is so versatile. Highly recommend.
March 2, 2014
Nice top
Really pretty and comfy. Dress up or down. Adore the bright blue and especially, the navy polka dot. Was thrilled that one, originally sold out, was available online! Must haves for spring or all year! Nice fit but sleeves a bit long on medium and last two buttons make it snug at the hip. A little long but fine. Otherwise awesome.
February 28, 2014
Great shirt!
I have three of these shirts. Great fit. True to size. Comfortable. The material is thin, I wear with a cami. Great under a blazer or alone.
February 21, 2014
Great shirt
Very versatile shirt! Can be worn with jeans for a casual look or dressed up with dress pants!
February 20, 2014
Love IT
Nice fit perfect colors really adore this product so I have now purchase a total of 4
February 20, 2014
These shirts are timeless!
I love this shirt, because it can be paired with pretty much anything. It is fool proof and my go to top on days that I am running late for work and have no time to put together an elaborate outfit. It looks awesome with pencil skirts, pants, denim. I wear it with a nude cami underneath. I also love the fact that it comes in several really good colors that looks great on anybody.
February 20, 2014
(3 Questions & 6 Answers)
Product Q&A
Ask your questions. Share your answers.
Size : Scolors: Hottest Pink, Blue, Green, Red, light pink (Blush)
Please could you let me know if any stores have these? online my size is not available.
Thank you.
4 months ago
Thank you for the question! This blouse definitely might be in a store near you. If you click the "Find In Store" button while on the product page, you will be able to enter your zip code and then check for availability in the size you desire in a store closest to you. Thanks again!4 months ago
New Albany, OH, USA
the blush is gorgeous!4 months ago
Age: In my 30s
Body Type: Petite
Shopping Frequency: Frequently
Yes, a lot of stores carry them. You will need to call ahead of time, as I noticed the smaller stores have limited colors and sizes.2 weeks ago
Age: In my 30s
Body Type: Long and Lean
Shopping Frequency: Frequently
Chicago, IL
2 months ago
Thank you for the question! Many of our seamless camis (item #4982302) match or coordinate well with the Ashton Blouse. For this engine red Ashton, we recommend the seamless cami in the color flame. Thanks again!1 month, 3 weeks ago
New Albany, OH, USA
White or tan work great though i feel the colorful tops dont need it1 month, 1 week ago
Age: In my 20s
Body Type: Petite
Shopping Frequency: Frequently
Union NJ
In store the tag for this blouse says that it comes in petite sizes online. But I haven't seen them on the website.2 months, 1 week ago
Thank you for the question! Our Petites line will launch on our website on Feb. 19th. Please definitely come check back then!1 month, 3 weeks ago
New Albany, OH, USA
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1 of 1


text:
The Harris Woodscraper is an easy solution for removing paint from wooden surfaces. Contains 4 hardened super sharp scraping edges (2 fine and 2 rough).
*Free delivery over £50 refers to home delivery orders placed on diy.com only. Charges refer to the value of goods being delivered and excludes delivery from stores or services. Excludes bulk delivery.
B&Q accepts the above cards and also offers a range of in-store financial services. Learn more
© B&Q 2014 - Terms & Conditions


text:
crazymilkshake5 wrote:In a twist that nobody saw coming!
I always find it best to strike when everyone least expects it
Moderators: Cartographers, Global Moderators
crazymilkshake5 wrote:In a twist that nobody saw coming!
thenobodies80 wrote:[Moved] Back to the forge
I will look into it asap
AndyDufresne wrote:Almost forgot about this map, I'll have to give it a look over again!
dolomite13 wrote:So ... hows this lookin? xml check out?
nolefan5311 wrote:dolomite, please upload the XML file into this thread.
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text:
LONDON, July 4 (Reuters) - British spot gas prices pared
back gains on Thursday as warm weather curbed demand, leaving
the system oversupplied.
Gas for Friday delivery was trading 0.60 pence
lower at 64.55 pence per therm at 0737 GMT. Prices had been
gaining ground over the past couple of weeks.
'The system opened long this morning, which is a bearish
factor for (the within-day) contract and may pull down other NBP
prompt prices,' Point Carbon analysts said.
Oversupply was due to lower consumption, higher Norwegian
exports as production at the Kollsnes gas processing plant
resumed after a power failure and lower IUK pipeline exports,
they added.
The British gas system was oversupplied by 6.4 million cubic
metres (mcm) on Thursday, National Grid data showed.
Gas demand on Thursday was forecast at 156.4 mcm, below the
seasonal norm of 206.8 mcm, as warm weather curbed central
heating demand in many parts of the country.
Temperatures were expected to remain above 21 degrees
Celsius for the remainder of the week, according to Britain's
Met Office, with highs of 27 degrees on Sunday.
It forecast 'a good deal of fine, dry and increasingly warm
weather' over the next five-day period.
Conditions should remain fine, dry and settled across
Britain over the next fortnight, it added.
'With LNG send outs from South Hook and BBL remaining
reduced since July 1, the UK system needs medium-range storages
to balance dampening the downward price movement,' Point Carbon
On the power side, day-ahead baseload power fell
1.22 pounds to 47.13 pounds per megawatt hour.
EDF Energy restarted unit 8 at its Heysham nuclear
power plant in the early hours of Thursday, after an unplanned
outage, the company said.
(Reporting by Nina Chestney; editing by James Jukwey)
((email@example.com)(44 207 542 8071)(Reuters
UK natural gas prices
National Grid instant flows
National Grid gas demand
North Sea gas and power maintenance
UK: baseload prices, peakload prices,
FRANCE: baseload prices, peakload prices, outages, report
GERMANY: baseload prices, peakload prices, outages, report
CENTRAL EUROPE: report
SWITZERLAND: outages, reservoir levels
NORDIC: report
Keywords: MARKETS BRITAIN GAS/POWER
(Xtra clients: Click on http://topnews.session.rservices.com to see Top News pages in multimedia Web format.)) )
Copyright Thomson Reuters 2013. All rights reserved.
The copying, republication or redistribution of Reuters News Content, including by framing or similar means, is expressly prohibited without the prior written consent of Thomson Reuters.


text:
- 11-14-2012, 11:58 AM Thread Author #1
i have a BB10 PRE-ordered!!!! my phone company(BELL) took my name and number and is going to order
my mobile phone company took my name and number for a pre-order of the bb10 two weeks ago. im frist on the list. as soon as they get the word to take orders i get a phone call to place mine. i dont know if this is all stores or just my local one. but they have a list going.>>>>>> im so stoked BB10 BB10 BB10!!!!!!
hmm maybe let us know when you get the call and I'll beleive they're not just telling you what you wanna hear.
Pre-Order implies you set down money. You don't have a pre-order. You just have some nice store reps who may / may not call you when they hear it's coming. Which, realistically will likely be after the rest of the world already knows. Still, nice to hear they're taking names and showing interest.
There are three things all wise men fear: the sea in storm, a night with no moon, and the anger of a gentle man.
[ Mobile Nations Sites: Android, iOS, Windows Phone, BlackBerry, Smartwatch Fans] - 11-14-2012, 12:50 PM Thread Author #4
well ive done this with my other devices and got a call samsoung iphone and playbook
- 11-14-2012, 01:00 PM Thread Author #5
maybe i should of called it a "per-pre order" lol
Did they mention a price? I knownthe answer but have to ask
- 11-14-2012, 03:39 PM Thread Author #7
No thats what the call well be about . They well call tell me with the price specs and when i can excpect delivary and i ether go a head with the order or well not...... i know i well order two. I have a co worker who has informed me she has done the same.
Thanked by:Shanerredflag (11-14-2012)
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11-14-2012, 04:56 PM #9"Hard work spotlights the character of people: some turn up their sleeves, some turn up their noses, and some don't turn up at all." -Sam Ewing
Rollin' on Twitter - 11-14-2012, 05:59 PM #10
Sounds like someone is playing around with your feelings. WE didn't even know about the Launch of BB10 until Monday of This week. TWO weeks ago you "pre-ordered and they "wrote your info down?" Sounds like BS to me. You would Not pre-order a phone that far EARLY without Knowing exactly when they would do an announcement and from this Monday, 2 days ago they Did the announcement so I think you were just a ginnea pig to see who is that gullible.
I wait for the future...to COME back to BlackBerry! - 11-14-2012, 09:41 PM #11
I have a pre order in my pocket too. I hope the sales people get their sleep the night before because I'll be there before they are.
BB10 Powered by QNX RTOS. - 11-15-2012, 06:38 PM Thread Author #12
Ordering with out reading reveiws? and what reveiw well i read thats going to be non-biase or mention apple inc. four times before im done reading. i well buy bb10 and make my own reveiw . after reading the bs and plan out lies of the past 16 months there isnt anyone out there thats going to write anything that im going to trust. well this site and one other seems to state the good and the bad in a awnest manner.
Thanked by:DisturbedRocks31 (01-14-2013)
did you get a L or N device?
- 11-15-2012, 06:53 PM Thread Author #14
at this point i well buy any bb over i this or i that....... why is it gullible for a sales rep to call to make a sale, or for me to set in my office to order my next phone while im getting thinks done. well i gusse i could drive across town and stand in a line to give me credit card number name and bla bla bla ....... then when the phone comes in ill drive across town stand in line and get my phone. all i gotta say is.thanks bell for saving me some time in getting my next phone.>>>>>> when bb10 is avalible my order well be in. why is this so complacated ?
Last edited by Ronstermadness; 11-15-2012 at 07:04 PM.
- 11-15-2012, 06:55 PM Thread Author #15
when they call i well get which ever one is avilable. and the other i well get when its released.
- 11-15-2012, 07:21 PM #17Remember to RTFM.
- 11-16-2012, 09:56 PM Thread Author #18
So did you read the part were in ordered my last three devices this way? Maybe they were just humoring me then to. Anyway I'll update when I get the call and let ya know price.
- 11-18-2012, 11:24 PM Thread Author #20
Wow! I wasn't trying to say I would know info on bb10 before anyone else. I was just saying I'm getting the phone. As soon as it's released my order is placed. There is no other decision to be made. My order is placed. I'm excited about it.
- 11-19-2012, 07:49 AM #21Lovin' the Playbook and hatin' the cynics!Thanked by:
Ronstermadness (11-19-2012)
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11-19-2012, 10:51 AM #23i have a BB10 PRE-ordered!!!! my phone company(BELL) took my name and number and is going to order
You wasted your money and they are just fooling with you, there is no pre-order available or possible at this time.
Sent from my BlackBerry 9860 on 18.104.22.1684 with Tapatalk and my fingersThanks For Reading My Post - 11-19-2012, 11:05 AM #24Sent from my jail cell using a corrupt prison warden
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11-19-2012, 11:10 AM #25Thanks For Reading My Post
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Kenneth R. Norman , Ph.D.Assistant Professor
e-mail: firstname.lastname@example.com
2000 - Ph.D. from University of British ColumbiaCurrent Research
The versatile signaling molecule calcium (Ca2+) is required for many cellular functions required for life including fertilization, cell proliferation, secretion, transcription, metabolism and muscle contraction. Paradoxically, Ca2+ is also involved in cell death, and excitotoxicity in the nervous system. Therefore, the regulation of intracellular Ca2+ levels is critical for cellular function and survival. Unlike other signaling molecules, Ca2+ cannot be degraded, synthesized or modified, and yet calcium levels are dynamically modulated. Thus, many proteins are required for the proper regulation of intracellular Ca levels. Our research has focused on the interesting biological question of how Ca2+ is regulated at the cellular level, and how Ca2+ dysregulation affects animal behavior and development. Thus far, we have focused on several gene products and their regulation of Ca2+ oscillations in the soil nematode, Caenorhabditis elegans. C. elegans has a number of features that make it an outstanding model system for elucidating cell signaling mechanisms. First, C. elegans is readily grown in the laboratory on a diet of Escherichia coli. Second, it proliferates rapidly, within three days C. elegans develops from a fertilized egg to an adult. Furthermore, an individual adult can produce 300 progeny, which enables large-scale production of several million worms per day. Third, C. elegans is transparent so development of muscle, intestine and the nervous system can be easily observed. Moreover, with the use of fluorescent markers, changes in Ca2+ dynamics as well as protein localization at the subcellular level can be readily determined in living animals. Lastly, C. elegans homologues have been identified for 60-80% of human genes. Thus far, we have found that VAV-1, a homolog of the proto-oncogene Vav, acts to regulate intracellular Ca2+ oscillations via the Rho GTPases and IP3 signaling. In VAV-1 mutants, as well as these downstream effectors, several rhythmic behaviors are disrupted. These include pharyngeal muscle pumping, which is required for feeding, gonadal sheath cell contractions and spermatheca dilation, which are required for fertilization, and the defecation motor program, which consists of three motor steps that occur every 45 seconds. These data suggest that VAV-1 acts as a master regulator of biological rhythms. Using these simple rhythmic behaviors as a model system, our long-term research goal is to identify the mechanisms that regulate intracellular Ca2+ signaling and determine the cell signaling pathways that regulate rhythmic behaviors. Specifically, our research will focus on addressing the following questions: 1) What are the molecular events required to stimulate VAV-1 signaling and rhythmic behavior? 2) What are the other gene products involved in VAV-1 and Ca2+ signaling?
- Norman KR, Maricq AV. Innexin function: minding the gap junction. Curr Biol. 2007 Sep 18;17(18):R812-4.
- Norman KR, Cordes S, Qadota H, Rahmani P, Moerman DG. UNC-97/PINCH is involved in the assembly of integrin cell adhesion complexes in Caenorhabditis elegans body wall muscle. Dev Biol. 2007 Sep 1;309(1):45-55.
- Norman KR, Fazzio RT, Mellem JE, Espelt MV, Strange K, Beckerle MC, Maricq AV. The Rho/Rac-family guanine nucleotide exchange factor VAV-1 regulates rhythmic behaviors in C. elegans. Cell. 2005 Oct 7;123(1):119-32.
- Mackinnon AC, Qadota H, Norman KR, Moerman DG, Williams BD. C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes. Curr Biol. 2002 May 14;12(10):787-97.
- Norman KR, Moerman DG. Alpha spectrin is essential for morphogenesis and body wall muscle formation in Caenorhabditis elegans. J Cell Biol. 2002 May 13;157(4):665-77.


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By: Evenflo
Item ID: EV804-11347
Our Price:$49.99
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For free in-store pick up, please allow 24-48 hours for processing of your order. Once your order is ready, you will be notified when to pick up your order.
Give your stroller a little spunk and pop with the Snugli Stroller Style Set in Pink Geo. Easy to to change, and available in a variety of colors, the possibilities are endless! Generously cushioned and made of durable and quality material, these sets are easy to remove and machine wash.


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LOS ANGELES (AP) - Imagine stepping into a car-sized capsule in downtown Los Angeles and, 30 minutes later, emerging in San Francisco
LOS ANGELES (AP) - Oprah Winfrey says she's "sorry" that a media frenzy emerged after saying she experienced racism during a trip to Switzerland.
BOSTON (AP) - The guilty verdicts against James "Whitey" Bulger brought catharsis and closure to relatives of the 11 victims in whose killings he was convicted of playing a role, but for the families of the eight people whose deaths couldn't be definitively linked to the Boston mob boss, peace will be harder to come by.
WASHINGTON (AP) - Joe Biden may run for president in 2016, or he may not. But he wants you to know he could.
SAN DIEGO (AP) - A 16-year-old girl who was rescued during an FBI shootout with her captor in the Idaho wilderness is resting at home with family and friends to begin what her father says will be a slow recovery.
While Republicans argue among themselves over what to do about Obamacare - Defund it? Delay it? Give up the fight to repeal it? - a coalition of wealthy and determined liberal groups is preparing to strike back at GOP efforts to stop the president's health care scheme.
As Time Warner's blackout of CBS stations continues, it is time for the public to take sides.
SAN JOSE - All I know about climate, some say, is what's outside my window.
I am not a real big fan of baseball (NFL yes), and I have to comment on its convoluted disciplinary form of punishment for all of the dopers being suspended recently and the suspensions the MLB is handing out currently and in the past.
Re: letters about salty water, Signal, 8/1/13:
Living with Children
LOS ANGELES (AP) - Adrian Gonzalez scored the go-ahead run on Yasiel Puig's sacrifice fly that capped a three-run sixth inning, helping the Los Angeles Dodgers beat the New York Mets 4-2 on Monday night for their sixth straight victory.
WASHINGTON (AP) - Attorney General Eric Holder announced a major shift Monday in federal sentencing policies, targeting long mandatory terms that he said have flooded the nation's prisons with low-level drug offenders and diverted crime-fighting dollars that could be far better spent.
NEW YORK (AP) - Minus Mariano Rivera in the ninth inning, the New York Yankees used a pair of relievers to close out the Los Angeles Angels 2-1 Monday night and preserve the win for Hiroki Kuroda.
SACRAMENTO, Calif. (AP) - California on Monday became the first state to enshrine certain rights for transgender K-12 students in state law, requiring public schools to allow those students access to whichever restroom and locker room they want.
We all know that perception often influences our decisions, yet we catch ourselves and become reminded that what we perceive isn't always what's really going on. With the constant barrage of information available in today's 24/7 world, it's important to not get caught up in the day-to-day market volatility and news headlines. That daily hype doesn't always dovetail with what Wells Fargo Advisors top strategists are observing in the financial marketplace.
Bayless is…
With everything from nationally ranked academic programs to effective career education opportunities and college placement services, Hart district students are afforded every opportunity to excel in an increasingly competitive academic environment.
Whether priorities are schools, recreation or convenience and friendly neighborhoods, home buyers are finding that Fair Oaks Ranch by Pardee Homes fills the bill.


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The latest breakthrough in boxing glove technology, Ringside IMF Tech™ gloves feature an innovative injected molded foam system. With 2.5" of protection across the knuckles, these training gloves take safety and durability to the next level. All leather construction.
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3 BDRM 2.5 BATH IRON CREEK TOWNHOME in Apartment Rentals in Blue Springs, MO
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3 BDRM 2.5 BATH IRON CREEK TOWNHOME Apartments Description
Prime location in Iron Creek, this 3 bedroom 2.5 bath townhome features spacious living areas with washed-oak accent trim and cabinetry, fully equipped kitchen including electric range, dishwasher, microwave, disposal and refrigerator. Central air, ceiling fans, fireplace, mini-blinds, full laundry hookups and walkout slider to patio. Single car garage with opener too! Lawn care provided. Call for more details or to schedule an appointment to see inside..... One Year Lease with Early Release Options
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Vitamin B6 (as pyridoxine HCl) | 100 mg | 5,000% |
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Lymphangiogenesis: Molecular Mechanisms and Future Promise
Cell, Volume 140, Issue 4, 19 February 2010, Pages 460-476
Tuomas Tammela and Kari Alitalo
SummaryThe growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of pathological processes including tissue inflammation and tumor dissemination but is insufficient in patients suffering from lymphedema, a debilitating condition characterized by chronic tissue edema and impaired immunity. The recent explosion of knowledge on the molecular mechanisms governing lymphangiogenesis provides new possibilities to treat these diseases.
Summary | Full Text | PDF (3084 kb) - Molecular lymphangiogenesis: new players
Molecular lymphangiogenesis: new players
Trends in Cell Biology, Volume 15, Issue 8, 1 August 2005, Pages 434-441
Tuomas Tammela, Tatiana V. Petrova and Kari Alitalo
AbstractThe function of the lymphatic vascular system as a conduit for immune cells and excess tissue fluid has been known for over a century, but the molecular players involved in lymphangiogenesis – the formation of lymphatic vessels – have remained unknown until recently. Signals mediated by vascular endothelial growth factor-C, the homeodomain transcription factor PROX1 and the forkhead transcription factor FOXC2 have been implicated in the growth, morphogenesis and hierarchic organization of the lymphatic vascular network. Recent results have also shown the importance of the angiopoietin–Tie and ephrin–Eph signaling systems in lymphangiogenesis, suggesting that these pathways regulate the lymphatic vascular system in a manner similar to, yet distinct from, their regulation of angiogenesis. This review provides an overview of the molecular players involved in lymphangiogenesis, with special emphasis on recently discovered molecular mechanisms.
Abstract | Full Text | PDF (375 kb) - PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis
PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis
Cancer Cell, Volume 6, Issue 4, 1 October 2004, Pages 333-345
Renhai Cao, Meit A. Björndahl, Piotr Religa, Steve Clasper, Stina Garvin, Dagmar Galter, Björn Meister, Fumitaka Ikomi, Katerina Tritsaris, Steen Dissing, Toshio Ohhashi, David G. Jackson and Yihai Cao
SummaryCancer metastases are commonly found in the lymphatic system. Like tumor blood angiogenesis, stimulation of tumor lymphangiogenesis may require the interplay of several tumor-derived growth factors. Here we report that members of the PDGF family act as lymphangiogenic factors. In vitro, PDGF-BB stimulated MAP kinase activity and cell motility of isolated lymphatic endothelial cells. In vivo, PDGF-BB potently induced growth of lymphatic vessels. Expression of PDGF-BB in murine fibrosarcoma cells induced tumor lymphangiogenesis, leading to enhanced metastasis in lymph nodes. These data demonstrate that PDGF-BB is an important growth factor contributing to lymphatic metastasis. Thus, blockage of PDGF-induced lymphangiogenesis may provide a novel approach for prevention and treatment of lymphatic metastasis.
Summary | Full Text | PDF (1183 kb) - …more
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Copyright © 2010 Elsevier Inc. All rights reserved.
Developmental Cell, Volume 18, Issue 3, 437-449, 16 March 2010
Add/View Comments (0)Regulation of Developmental Lymphangiogenesis by Syk+ Leukocytes
Ruben Böhmer1, Brit Neuhaus1, Sebastian Bühren1, Dayong Zhang1, Martin Stehling2, Barbara Böck1, 3 and Friedemann Kiefer1, ,
1 Department of Vascular Cell Biology, Max-Planck-Institute for Molecular Biomedicine, Röntgenstraße 20, D-48149 Münster, Germany
2 Flow Cytometry Unit, Max-Planck-Institute for Molecular Biomedicine, Röntgenstraße 20, D-48149 Münster, Germany
3 Present address: German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany
► Syk−/− embryos show vascular defects and lymphatic hyperproliferation ► Syk is expressed in a mononuclear cell population, not endothelial cells ► In Syk−/− embryos, the mononuclear cells accumulate near vessels ► Syk+ cells produce angiogenic factors that stimulate lymphangiogenesis
- Video Abstract (7.53 MB)
- Lymphatic vessels are essential for tissue homeostasis and immune surveillance and contribute to pathological conditions. Lymphatic endothelium differentiates from veins and forms an independent vascular tree with only few connections to the venous circulation. Failure of blood and lymphatic vessel separation results in hemorrhage and edema. VEGF-C and -D are strong inducers of lymphangiogenesis and have essential (VEGF-C) and modulatory (VEGF-D) roles during developmental lymphangiogenesis. We describe here a myeloid population that is defined by expression of the tyrosine kinase Syk, comprises largely M2-polarized mononuclear cells, and robustly expresses angiogenic factors, including VEGF-C/-D and chemokines. These cells stimulate lymphangiogenesis in vivo. Deletion of Syk causes increased chemotractant production, enhanced transmigration, and accumulation in the skin. Ensuing lymphatic hyperplasia and vessel dilation cause the formation of blood-lymphatic shunts. This mechanism does not involve circulating endothelial progenitor cells and demonstrates the potential of hematopoietic cells to control developmental lymphangiogenesis.


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Carthage O.S.B. Plant 1199 C.R. 201Carthage, Texas 00000000075633 Panola County Population: Rural Industry: Lumber And Wood Products
Carthage Primary School 1.89 miles S Libby Elementary School 1.98 miles S Carthage Junior High School 2.11 miles S Panola Junior College 2.25 miles S Baker - Koonce Intermediate School 2.37 miles SW |


text: Automotive DesignLine Blog Kickin' Tires: Part 2 Rick DeMeis11/7/2006 10:00 PM EST 0 comments post a comment NO RATINGSLogin to Rate Tweet From the Boston Auto Show, we continue our look at some of the auto electronics developments car makers have in store for the 2007 models. Hard disk drives (HDDs) are coming into their own for automotive use. Infiniti's G35 has an HDD navigation system which can be updated at the dealer via a Compact Flash slot in car's instrument center stack. The 30 gig drive is also portioned for 9.5 gigs of music storage. The nav function also has optional XM Satellite Radio traffic updates. Chrysler's new Sebring design uses a 20 gig HDD for its navigation system. For being cool or hot, depending on your point of view, the Sebring has twin cup holders that use thermoelectric elements to heat or cool the contents of your drink. Temperature of the holders can range from 140-35F. In the hybrid electric drive area, Nissan announced a hybrid version of the Altima for sale next year. The car will feature Toyota's hybrid architecture. A button just inside the open rear hatch on Ford's new Edge crossover electrically unlatches the rear seats to flip them down for extra room when loading cargo. The Edge also has a "slot" to hold a driver's iPod.


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July 27th - August 3rd
Please be patient as we convert to our new online registration program!
This Years Events:Grand Parade Map (updated!)
Orchard Days Sponsorships:Vendor Opportunities:Family Night (July 29th) click on Register, then Orchard Days Aug. 3rd Park Vendor (Craft and Food) click on Register, then Orchard Days Rodeo Vendors (Aug 2-3rd) click on Register, then Orchard Days CHANGE TO AVOID CHANGE
Thank you for your overwhelming support! In times of economic challenge, our celebrations sponsorships suffer. Regardless, we want to put on the best celebration ever and ask for your help. Please consider rounding up your utility payment to an even dollar amount. Not only will the additional change go directly to 'Orchard Days', it will make balancing your check book easier. |
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Have a functionality, fit, or otherwise product-specific question about the Thexton Activator Battery Filler? Ask it here! If you have a customer service or shipping question, please direct it to our Customer Service department.
Product Style | RevZilla SKU ID | Manufacturer Product # | Availability |
Thexton Activator Battery Filler | 176958 | 604 | In Stock: Ships within 24 hours |


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In South Dakota, there is no doubt that immigrant entrepreneurs and innovators play an important role. Immigrant entrepreneurs bring in additional revenue, create jobs, and contribute significantly to the state's economy. Highly skilled immigrants are vital to the state's innovation industries, and to the metropolitan areas within the state, helping to boost local economies. Furthermore, local government, business, and non-profit leaders recognize the importance of immigrants in their communities and support immigration through local "welcoming" and integration initiatives.
Immigrant entrepreneurs contribute to South Dakota's economy.
- From 2006 to 2010, there were 606 new immigrant business owners in South Dakota, and in 2010, 1.2 percent of all business owners in South Dakota were foreign-born.
- In 2010, new immigrant business owners had a total net business income of $13.1 million, which is 0.5 percent of all net business income in the state.
Highly skilled immigrants are vital to South Dakota's innovation industries, which in turn helps lead American innovation and creates jobs.Read more...
Published On: Wed, Oct 01, 2014 | Download File