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FAQs: Applying for Graduate Admission to SLU
Read our FAQs for International Applicants
(Q) How do I find out the status of my Graduate admission application?
(A) If you applied online and would like to check your application status, you can do so by logging in with the Login ID and pin you created when you applied: Check my Application Status
Applicants who have submitted, but not completed, their application for admission will receive a monthly e-mail reminder with a progress update of their application. If you do not receive an e-mail within two weeks from your application, please contact Graduate Admission at email@example.com
(Q) How do I qualify for an assistantship to help pay for my Graduate Education?(A) Please note there are no additional forms you need to fill out to be considered for an assistantship. All assistantships are awarded by individual departments, and not through Graduate Admission. Please contact the department you are applying to for more information about available assistantships.
(Q) How can I be considered for a Graduate Fellowship?
(A) Fellowships are awarded to a newly accepted Master's or Doctoral level students who demonstrate outstanding scholastic achievement and potential for success.
(Q) Can I apply to a Graduate program with unofficial copies of University transcripts or GRE scores?
(A) No. Your application will not be processed until OFFICIAL copies of all documents are received. Photocopies and faxes will not be accepted. If you have an exceptional or extraordinary circumstance, please communicate this to the admissions staff at Graduate Admission.
(Q) Is it okay to send supporting documents, such as letters of recommendation and transcripts, to the Graduate Admission office separate from my application?
(A) Although we encourage self-managed applications -- applicants collecting and then sending their materials together -- we will accept documents sent separately. Self-managed applications will be processed faster.
Send supporting documents to:
Saint Louis University
Graduate Admission
221 N. Grand Blvd., Suite 150
St. Louis, MO 63103
(Q) If I received my undergraduate degree from Saint Louis University. Do I still need to send these transcripts to the Graduate Admission office?
(A) Yes. You will need to contact the Registrar at (314) 977-2269 to request transcripts to be sent.
(Q) Do I need to send transcripts from every college I have previously attended?
(A) Yes. We will need all transcripts from all previous universities attended.
(Q) Can I apply to more than one program?
(A) Yes. Students interested in completing concurrent degrees will be evaluated on a case-by-case basis. Please contact both departments to determine eligibility and policies for a concurrent enrollment. There are also dual-degree programs which require prospective students to apply to both degree programs.
(Q) What are the minimum scores for the GRE to be considered?
(A) Each department has different requirement standards for graduate admission tests like the GRE General and/or Subject. Prospective students should contact the department of your interest for specific information regarding test score requirements.
(Q) How do I schedule a campus tour?
(A) Tours of the campus are arranged through Campus Visits in the Office of Admission. They can be contacted at (314) 977-2500. To meet faculty and for a tour of your department, please contact the department directly.
(Q) Who do I contact with questions about my VISA?
(A) Please contact Cathy Donahue in the Office of International Services with questions regarding your VISA.
(Q) Do I have to submit the Declaration of Finances Form before being accepted?
(A) Yes, you will need to submit the Declaration of Finances form along with your application materials to expedite the processing of your I-20 and VISA if you are accepted. Your file will not be considered complete until the Declaration of Finances form is submitted.
(Q) Does Saint Louis University participate in the International Study Candidate Assesment Process (ISCAP)?
(A) Yes. Saint Louis University has partnered with International Skill Verification Services (ISVS) to interview applicants from the People's Republic of China, Hong Kong, India, Thailand, Indonesia, Japan, Malaysia, South Korea, Taiwan and Vietnam. Your participation in the ISVS International Study Candidate Assessment Process (ISCAP) will enable us to provide greater consistency in evaluations and deliver faster and more efficient response times for admissions and scholarship decisions. SLU, therefore, strongly suggests that all applicants from the People's Republic of China, Hong Kong, India, Thailand, Indonesia, Japan, Malaysia, South Korea, Taiwan and Vietnam register and complete the ISCAP. ISVS will conduct interviews and assessments on our behalf in local centers in Beijing, Shanghai and Guangzhou.
The ISCAP is a guided interview-based process that requires no specific preparation. It is designed to give universities a better sense of your spoken English and ad hoc English writing skills, as well as give you the opportunity to powerfully share who you are with us. Please visit the ISVS website for more information and to schedule your interview.
(Q) What are the minimum scores for the TOEFL to be considered for admission?
(A) You must obtain a score of 550 or higher on the paper-based TOEFL and a TWE score of at least 4.0 OR a score of 213 or higher on the computer-based TOEFL and a TWE score at least 4.0 OR a score of 80 or higher on the interent-based TOEFL and TWE score of 4.0.
You may also submit a Cambridge IELTS with an overall band score of 6.0 or higher. IELTS | TOEFL scores
(Q) Do I need to send my TOEFL scores? (international students only)
(A) All international students are required to take the TOEFL to be considered for admission. You may send IELTS scores in place of TOEFL scores. If you have attended an American University, the TOEFL score requirement may be waived.
Saint Louis University is asking international applicants to submit their test scores electronically. Saint Louis University's institutional code is: 6629
For more information online, visit the International Services Center web site.


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It's Hatched! 57 Bought
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subset: commoncrawl


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A Clinical Study to Compare Combination of Aliskiren+ HCTZ to Irbesartan+ HCTZ or Amlodipine+ HCTZ or HCTZ Alone in Obese Hypertensive Not Responsive to HCTZ 25 mg
This study has been completed.
Information provided by (Responsible Party):
ClinicalTrials.gov Identifier:
First received: September 12, 2005
Last updated: November 7, 2011
Last verified: June 2006
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
To evaluate the blood pressure lowering effects of the combination of aliskiren 300 mg and HCTZ 25 mg in obese patients with essential hypertension inadequately treated with HCTZ 25 mg, compared to irbesartan or amlodipine with HCTZ or HCTZ alone.
Condition | Intervention | Phase |
Hypertension |
Drug: aliskiren |
Phase 3 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Parallel Assignment Masking: Double-Blind Primary Purpose: Treatment |
Official Title: | A 12-week Randomized Double-blind Parallel Group Study to Evaluate the Efficacy and Safety of the Combination Aliskiren With HCTZ Compared to Irbesartan or Amlodipine With HCTZ or HCTZ Alone in Hypertensive Patients With BMI ≥ 30 kg/m2 Not Adequately Responsive to HCTZ 25 mg |
Resource links provided by NLM:
Further study details as provided by Novartis:
Primary Outcome Measures:
- Change from baseline in mean sitting diastolic blood pressure after 8 weeks
Secondary Outcome Measures:
- Change from baseline in mean sitting systolic blood pressure after 8 weeks
- Evaluate number mean sitting systolic/diastolic response from baseline to weeks 4 and 8
- Mean sitting diastolic blood pressure < 90 mmHg or a reduction of > 10 mmHg after week 8
- Achieve mean sitting blood pressure control target of < 140/90 mmHg after week 8
Enrollment: | 493 |
Study Start Date: | January 2005 |
Study Completion Date: | March 2006 |
Primary Completion Date: | March 2006 (Final data collection date for primary outcome measure) |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria
- Patients with essential hypertension
- Patients with body mass index ≥ 30 kg/m2
Exclusion Criteria
- Severe hypertension
- History or evidence of a secondary form of hypertension
- History of Hypertensive encephalopathy or cerebrovascular accident.
Other protocol-defined inclusion exclusion criteria also apply.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00219115
United States, New Jersey | |
Novartis Pharmaceuticals | |
East Hanover, New Jersey, United States, 07936 | |
Germany | |
Investigative Centers, Germany |
Sponsors and Collaborators
Study Director: | Novartis Pharmaceuticals | Novartis Pharmaceuticals |
More Information
No publications provided
Keywords provided by Novartis:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on March 09, 2014
No publications provided
Responsible Party: | Novartis |
ClinicalTrials.gov Identifier: | NCT00219115 History of Changes |
Other Study ID Numbers: | CSPP100A2309 |
Study First Received: | September 12, 2005 |
Last Updated: | November 7, 2011 |
Health Authority: | United States: Food and Drug Administration |
Keywords provided by Novartis:
Hypertension, aliskiren, blood pressure, irbesartan, amlodipine, hydrochlorothiazide |
Additional relevant MeSH terms:
Hypertension Vascular Diseases Cardiovascular Diseases Amlodipine Irbesartan Calcium Channel Blockers Membrane Transport Modulators Molecular Mechanisms of Pharmacological Action |
Pharmacologic Actions Cardiovascular Agents Therapeutic Uses Vasodilator Agents Antihypertensive Agents Angiotensin II Type 1 Receptor Blockers Angiotensin Receptor Antagonists |
ClinicalTrials.gov processed this record on March 09, 2014


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Start the streaming media presentation in the stand-alone Player.
Sacramento County Child Support Manager Julie Prado shares employer child support basics.
Ana Vega and Bethany Cox explain how payments flow through the State Dispursement Unit (SDU).
How do you stop multiple documents coming in for the same person? John Contreras can help! He explains the Employer Data Maintenance function.
Tired of 18 page Income Withholding Order packets? Bill Stuart shares how the E-IWO process will make your life easier.


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Waterbury Office staff and drivers performed heroically in crisis
On Jan. 24, a gas leak (Jan. 25 article, "Schools evacuated after gas leak found") put students at North End Middle School and Wilby High School in danger.
The office staff and drivers at Durham School Services deserve our gratitude for their quick action. At least 60 drivers were needed to safely and quickly evacuate the students. Without hesitation, Durham went into action.
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- As war rages, some are 'snug and comfortable'
- Washington, Conn. Musical event drew a fine turnout
- Waterbury: Christmas decorations were pleasing


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In San Francisco, if you're Chinese, you get laid. If you're black, you get a gay friend.
-Amma of Our Little Theater [Paraphrase]
Tags: Amma sf san francisco comedy comedian jokes Our Little Theater stand-up bay area Favorite Things of Last Night
Bay-Area, CA based comedy blog from Bay-Area, CA based comedian blogger. News, event reviews, room reviews, journals, highlights, videos, links, and anything else from the San Francisco/Bay-Area comedy community.
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Homework Help
Better Students Ask More Questions.
Can you help me with some 9th grade work?no
1 Answer | add yours
There are a lot of different subjects covered in the ninth grade. You can get help from eNotes editors, but you would have to ask separate questions about math, history, literature, etc. I suggest you start by asking one question about one subject and using that subject as the topic rather than "Reference." A lot of ninth graders subscribe to eNotes and continue to get good advice all the way through high school and college. You would be welcome.
Posted by billdelaney on August 21, 2012 at 11:34 AM (Answer #1)
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skippyz's Forum Posts
Forum Post: Pats online
Just got off the hill feom a morning of skiing. The game isn't on in Colorad. Can someone give me the online link. Thanks.
Forum Post: Pats online
I live in Telluride, CO and due to the Donkeys being the only thing that matters in Colorado the Pats gasme isn't on tv. Can someone recommend where to watch online?
Forum Post: ESPN - The Mag: Pats don't make playoffs and Miami WINS AFC EAST!!
Odds to win Super Bowl NE 7-1 Mia 40-1
Odds to win AFC NE 3-1 Fish 18-1.
Guess ESPN needs to sell mags with their own version of reality.
Noone ever got rich betting against Vegas.
Forum Post: Disappointed in No. 12
In Response to Re: Disappointed in No. 12: [QUOTE]I don't think he tweets, so that's probably why you are overreacting. Can Brady take a dump without fans making a big deal out of every move or non-mo more »
Forum Post: BRADY FINALLY ORGANIZES TEAM WORKOUTS +SHOWS OFF HIS FORM WITH MORE MASCULINE HAIR AT CHARITY!
In Response to Re: Y CAN'T BRADY ORGANIZE TEAM WORKOUTS, WATER SLIDE WITH MALLET OR STOP MERRIWEATHER FROM RAPPING?: [QUOTE]In Response to Re: Y CAN'T BRADY ORGANIZE TEAM WORKOUTS, WATER SLIDE WITH MA more »
Forum Post: BRADY FINALLY ORGANIZES TEAM WORKOUTS +SHOWS OFF HIS FORM WITH MORE MASCULINE HAIR AT CHARITY!
Ever think maybe Brady is recovering from foot surgery? Seem like a lot of jealous folks begrudging the fact that he has a life and isn't holed up in his mothers basement during his recovery. Is there more »
Forum Post: who will slide in this draft?
Gotta agree with Newton. After watching the ESPN(sorry killa) special with Gruden I can see him falling. He could not tell Gruden how they called play at Auburn, told John he was putting him on the sp more »
Forum Post: VINCE WILFORK!
Yes I did. more »
Forum Post: VINCE WILFORK!
Forum Post: Crable Arrested
He got cut. Guess we need to talk about something else. more »
Forum Post: rate the 5 top teams on your hate meter.
I'm really surprised the Raiders didn't get more votes. In the late 70's the Raiders took up spots 1-5. Does time heal all wounds? more »
Forum Post: Too much business, too little heart
For the most part the days of players playing for one team their entire careers are gone. Free angency has seen to that. Before you get too sad about his departure just remember that in all llikelyhoo more »
Forum Post: Merriman might be in serious trouble with the Player Conduct Policy!
A walking perti dish and roid rage. New reality series? more »
Forum Post: BRADY OR BELICHICK... Who is most responsible for our dynasty?
Without Bill there is a very good chance we never have Brady. Maybe even a chance Brady never played in the league. No dis to Tom, but it's Bill. more »


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Warning: Do not use if you are pregnant, may become pregnant, breastfeeding, or taking anticoagulant drugs such as heparin or warfarin. May interfere with the absorption of iron; if you are anemic, take between meals. If you are taking any prescription drug, consult a physician before using this product. Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children. STORE IN A COOL, DRY PLACE.
Suggested Use: 2 tablets daily.
Disclaimer: This website is for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site. The statements made in this website have not been evaluated by the Food and Drug Administration. The products offered are not intended to diagnose, treat, cure, or prevent any disease. If you believe that you may have a disease condition, please consult your healthcare practitioner immediately, and before using any dietary supplement product.


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Community Outreach
Thank you for your interest in a donation from the Pittsburgh Zoo & PPG Aquarium to assist with your fundraising efforts. Every year the Zoo is able to fulfill numerous requests for admission passes (two passes per request) for local non-profit organizations. To request a donation, please mail a hardcopy letter on your organization's letterhead. For your request to be considered, your request letter must include your non-profit tax ID number, and a brief description of your organization and your event. Please include a self-addressed, stamped envelope with your request. Due to the high volume of requests that we receive, we are unable to participate in all of the worthy opportunities presented to us. Please note that the Pittsburgh Zoo & PPG Aquarium is not able to participate in requests from private individuals or for-profit businesses at this time. Letters of request can be mailed to: Pittsburgh Zoo & PPG Aquarium Attention: Donations
One Wild Place
Pittsburgh, PA 15206
Mascot & Chalk Artist Appearances
Our mascots and chalk artist love to visit events throughout the Pittsburgh area. You can request these services for your event. Requests can be made by mail or email, and must be received at least six weeks prior to your event. In your correspondence, please tell us about your event, anticipated attendance, and event location.
We will contact you approximately three to four weeks before your event to inform you if we are able to grant your request. Due to the popularity of the Pittsburgh Zoo & PPG Aquarium Mascots, not all requests can be fulfilled. Please note that Polar Bear, Sharky, and our chalk artist are not available for appearances at private events such as birthday parties or family reunions. Letters of request can be sent to:
Pittsburgh Zoo & PPG Aquarium Attention: Mascot Appearance
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Pittsburgh, PA 15206
firstname.lastname@example.com |


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We ship worldwide. The postage rates for your order are displayed before payment, which is processed using Paypal. You can pay using your Paypal account or any of the following cards:
Terrific arrangements by John Cale; Nico bleak but utterly captivating at the harmonium... a stone-cold classic.
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on all orders over $24.99* *see details
**Offer valid online only. Excludes Busy Day, Stretch Sole & Collegiate collections as part of order total calculation or discount. Taxes and shipping charges are not calculated as part of order total. Must enter code: LUCKY in cart. Cannot be combined with any other offer or promotion. Offer ends Thursday 3/13/14 at 11:59 pm MST.
**Valid on Economy shipping method only. Not valid on any other shipping method. Order total determined after any other discounts are applied and does not include any applicable taxes. Offer subject to change without notice. Limited time offer.
home > Work Shoes > Airlines > Crocswatt
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Idox provides local authorities with software & managed services which deliver seamless integration and automation from user interfaces through to document storage.
McLaren Software are leaders in Engineering Document Control, Collaboration and Computer Aided Facilities Management (*CAFM) software solutions. McLaren Solutions are used in over 45 countries helping owner operators, EPC contractors, AEC and asset owners design, build, operate and maintain safe efficient and compliant plants and facilities.
Combining comprehensive information management, online publishing, web design and development capabilities, offering complete online information solutions to our clients.


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Found October 30, 2012 on
- Former World Heavyweight Champion Bill Goldberg took fan questions on Twitter this afternoon and noted that he still trains 6 days a week. Here are some highlights:Could we see him in a wrestling ring again? "Yes.."Does he like Brock Lesnar? "1 of the few I still communicate with. Awesome dude."Does he like Triple H? "Funniest question all day…"Will he and Triple H ever make peace? "We're from 2 different planets…."With others performing in their 40′s, does he think it's wise to get back in the ring? "Tough call I'm struggling with"Is he friends with Shawn Michaels? "NO"
Original Story:
Goldberg Q&A: His Thoughts on Triple H & Brock Lesnar, Could We See a Return?, More
Bill Goldberg Says He's "Struggling" With Decision to Return to the Ring; Not a Fan of HHH or HBK
WWE Removes Goldberg Signs, Layla and Kaitlyn Argue, More
Bill Goldberg Comments on Beef with Triple H, Could We See Him Wrestle Again?, and More
WWE Removes Goldberg Signs at HIAC, Layla and Kaitlyn Argue About Loss, Young & O'Neil
WWE Removes Goldberg Signs at HIAC, Layla and Kaitlyn Argue About Loss, Young & O'Neil
WWE Forum Discussions
1 replies,
February 03, 2013
1 replies,
February 03, 2013
1 replies,
July 13, 2012
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Project learning can inspire the best of high-performance teamwork, or it can be devolve into unfocused chaos. How can we support each other to keep our eye on the prize? Share your project ideas, questions, and implementation experiences.
What do kids talk about?
When I first started reading about the Project Approach, I liked the idea of documentation -- methods where the teachers would somehow record the conversations of the kids. First this was to figure out what they talked about together to try to glean their interests and pick up on any ideas so that they could design projects around the kids' ideas, and then to record what they were saying when they were working on the projects.
I really liked this technique but don't read much about it for older kids. It certainly might be more difficult to "eavesdrop" on middle- and high-school kids, but the importance of picking up on what matters to them is no less.
I read a lot about teachers deciding on a project before school even begins. I'd like to see schools devote the first month to getting to know students through lots of activities and exposure to different things! Of course, this idea is anathema in the race to "cover the material," but there's no question in my mind that it would bear fruit in terms of producing the right intimacy between the kids themselves and the kids and the teachers.
How do teachers glean the interests of students without imposing their own notions of what students "should" be learning?


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We talk a lot about the Colorado Rockies' poor performance against teams like the San Francisco Giants and Arizona Diamondbacks, but there's another team that has an even tighter stranglehold on the purple pinstripers.
Since being swept by Colorado in the 2007 National League Division Series, the Philadelphia Phillies have completely owned the Rockies. Philadelphia is -- get ready for this -- 29-7 against Colorado during that time, including getting payback in the 2009 NLDS in a 3-1 series win. 29-7. Think about that. That's an .806 winning percentage. That's utterly insane.
But it's the cold hard truth. Not even a poor season -- by their standards, anyway -- by the Phils a year ago could help the Rockies, who dropped seven of nine contests to Philly en route to a 98-loss season.
Of course, the Phillies are a different club now, scuffling to a 32-35 start. Their offense, which has just two above-average regulars, is mediocre. And, while Cliff Lee is Cliff Lee, the pitching hasn't been great either, entering the series with a collective ERA+ of 98. Still, all you have to do is look at the Phillies from last year, who fell as many as 14 games below .500 before finishing with an 81-81 record, to see that this club has some fight left in them.
Domonic Brown is one of the two aforementioned starters who has been good. Brown, despite leaving a lot desired in the on-base department, holds an OPS+ 138 due to his 19 home runs and .576 slugging percentage. Chase Utley, while not the guy he used to be, posted a 118 OPS+ before landing on the disabled list on May 21.
The Rockies will be at a disadvantage with Troy Tulowitzki being out for at least a month, but they won't have to face Lee, who is 8-2 with a 2.55 ERA and, as usual, owns a strikeout-to-walk ratio of better than 5.00. They will see Cole Hamels, as shown below in the pitching matchups, but he has encountered some bad luck in addition to a spiked home run rate en route to a 2-9 record and a 90 ERA+.
For more on the Phillies, head over to The Good Phight. Also, I answered some questions leading up to this series for CBS Radio in Philadelphia. You can listen to the interview here.
Probable pitchers
Game 1: Friday, June 14 at 6:40 p.m. MT (ROOT Sports)
Kyle Kendrick (6-4, 3.22 ERA) vs. Juan Nicasio (4-2, 4.61 ERA)
Game 2: Saturday, June 15 at 2:10 p.m. MT (ROOT Sports)
Jonathan Pettibone (3-2, 3.70) vs. Tyler Chatwood (3-1, 2.14)
Game 3: Sunday, June 16 at 2:10 p.m. MT (ROOT Sports)
Cole Hamels (2-9, 4.45) vs. Jhoulys Chacin (4-3, 4.52)


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Our beginnings are in finishings. Since 1926, we've helped transform spaces with exquisitely crafted architectural trim. Today, we offer something you can't find anywhere else: complete Collections of interior finishings, from crowns to Ikons and architraves to interior doors – each element perfectly coordinated and flawlessly proportioned. Style that lives at the intersection of timeless and modern, of then and now.
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Five Collections, each with a number of unique Scenes and trim styles – coordinated and organized to make it easy to set your scene.


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CHARLESTON, W.Va. -- The West Virginia Democratic Party made automated phone calls Sunday to accuse Republican gubernatorial candidate Bill Maloney and the national Republican Governors Association of throwing state Republican lawmakers "under the bus."
The calls, which went to homes across the state, did not identify who paid for them.
A top Republican lawmaker called the robocalls "old-style tactics" and an act of desperation by Democrats.
The RGA has released two ads in the past two weeks attacking Gov. Earl Ray Tomblin for votes on bills that a majority of state House Republicans also voted for.
One RGA ad, released two weeks ago, claims Tomblin is trying to ration health care.
The ad cites a provision in a bill that's viewed as one of Tomblin's greatest legislative achievements: his plan to deal with billions of dollars in future health care costs for retired public workers. The ad claims the bill borrows ideas from President Barack Obama's health care reform law. While both call for cutting costs, neither calls for rationing.
The Tomblin administration received bipartisan support in the Legislature for its plan. The bill was approved by a unanimous vote in the 34-member state Senate and an 83-17 majority in the 100-member House of Delegates, which has 35 Republicans.
A second ad, released late last week, criticized Tomblin for "raising taxes on coal." The bill, to provide more money to clean up mine sites, was publicly supported by the West Virginia Coal Association. The bill passed the Senate unanimously - with one Republican senator not voting - and 85-14-1 in the House.
The robocalls, which went to Republican households in several state House districts, were meant to highlight what Democrats are calling the RGA's hypocritical message.
"We felt that it was necessary to make these calls because one of two things have taken place," Democratic Party Chairman Larry Puccio said in an email Monday.
"Obviously the Republican Governors Association has thrown the majority of Republican legislators under the bus for Maloney's personal gain who voted for this responsible legislation, or they have purposely attempted to mislead the public by not letting them know that this was bipartisan legislation, supported by most Republican legislators, that they are attacking in their ads."


text:
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Barbara Puett is a professional golfer and runs her own golf school. She is a regular columnist for Golf For Women magazine, has coauthored the book Golf Etiquette with Jim Alpfelbaum, and lives in Austin, Texas.Jim Apfelbaum is a senior writer for America Online's Golf magazine, and writes widely for golfing magazines. He is the author of Golf on $30 a Day and coauthored Golf Etiquette.
Barbara PuettJim Apfelbaum


text:
Break It Down, Super Bowl matchups: Vince Wilfork vs. Giants' O-line
To get you ready for Super Bowl XLVI, "Break It Down" will take a closer look at five matchups, one per day, that will be critical to the Patriots-Giants showdown.
Vince Wilfork was a man amongst boys Sunday. The Patriots' beefy defensive tackle proved nearly impossible to handle for Baltimore's offensive line, no matter where he lined up. He technically registered just 1.0 sack, but his presence in the Ravens' backfield altered several more plays.
Come Super Bowl Sunday, Wilfork most likely will find himself matched up against Giants center David Baas or right guard Kevin Boothe. That duo — and New York's entire offensive line — struggled mightily in pass protection at San Francisco.
How might New England use Wilfork two Sundays from now? Let's look back at the conference title games for some answers.
New England made a switch to a 4-3 base defense from its long-standing 3-4 look this season — possibly part of the reason that defense had so many issues at the start of the year. The Pats still employ some 3-4 techniques (two-gap principles, to be specific) and even revert back to the old 3-4 look at times (we'll get into the latter thought shortly), but the 4-3 gives New England a little more flexibility with how to use Wilfork.
We'll start with a third-down play for Baltimore in the second half, deep in Patriots' territory. Wilfork lined up over left guard Ben Grubbs, with Joe Flacco in the shotgun.
This play came after two-plus quarters of Wilfork wreaking havoc up front. As such, the Ravens paid him extra attention, with Grubbs getting inside help from center Matt Birk, who also provided some support for Marshal Yanda's block of Gerard Warren.
However, as you can see, that 3-on-2 protection in the middle led to some problems, namely, free pass-rushers elsewhere:
Let's rewind to Wilfork's only sack, which came on a 3rd-and-15 in the first quarter.
The Patriots utilized sort of a modified 3-4 look here, though they actually had just two defensive linemen (Wilfork, boxed in the middle, and Mark Anderson to his right) on the field. The third "lineman" was linebacker Rob Ninkovich, set as a defensive end.
But this setup left Wilfork over center Matt Birk.
As we saw time and again Sunday, Birk could not handle Wilfork one-on-one. The Giants definitely will take notice of that domination from Wilfork in situations where he's over the center — given what we saw Sunday from Baas, he'll have issues too.
On Wilfork's sack, Birk initially provided some room for Flacco. But when the Baltimore QB couldn't find anyone open, Wilfork used a strong swim move to blow by Birk, who had no help.
Baltimore had similar problems when it tried to block Wilfork straight-up in New England's four-man fronts as well. As illustrated by the first two pictures up top, when the Patriots went to four men on the line, Wilfork faced off against Grubbs.
Take notice of the blue line in the picture below — that's the original line of scrimmage for the play.
And look at how far Wilfork has driven Grubbs back:
That's seven yards deep, which makes it pretty easy to see why Flacco had issues on the play. Wilfork utilized that same force in the fourth quarter to blow up a critical 4th-down play.
With Baltimore down three and driving, the Patriots swapped back to a 3-4 look, with all three defensive linemen squeezed in tight near the ball. Ninkovich was standing up on the left edge of the D-line — the Patriots use him as a rush linebacker/lineman hybrid in a lot of packages (like that 3-4 we looked at earlier), but he stayed back almost as a spy on Flacco in this instance.
So, the Patriots sent three rushers.
Wilfork, up against Birk again, obliterated Baltimore's center.
Again, notice where the line of scrimmage is … and compare it to where Wilfork and Birk are as Wilfork gets his hand on Flacco.
How will the Giants counter Wilfork's sheer power up front? Are the Giants even capable of fully countering?
Sunday wasn't the best performance for Big Blue's O-line, which allowed six sacks and had major, major trouble dealing with Ray McDonald inside.
San Francisco's 3-4 featured, for most of Sunday's game, McDonald in the middle, flanked by Aldon Smith and Justin Smith on either side of him. In the play below McDonald lined up over top of Baas, the Giants' center.
You're going to notice right away the types of problems the Giants had Sunday, many of them coming because they simply could not block San Francisco's pass-rushers in one-on-one situations.
McDonald forced Baas to get some inside help from right guard Chris Snee, which in turn, freed up Aldon Smith to stunt inside and come clean against Manning.
Why were the Giants forced to provide Baas with some extra assistance? Well, here's an example of what happened when Baas tried to block McDonald — who gives away at least 30 or 40 pounds to Wilfork — by himself. Bass, No. 64, let's McDonald push past him.
The combination of speed and power proved to be too much, repeatedly, for Baas to deal with. In Baas' defense, he hobbled off the field early with what was described as an "abdominal contusion," so he likely played most of this game at less than 100 percent.
Still, he did not hold up well in passing situations.
But it wasn't just Baas. When the 49ers showed four men up front — with Aldon Smith standing up on the right side of the line — that pushed Justin Smith inside against Kevin Boothe and shifted McDonald over opposite Snee.
On this play in particular, Baas came over to help Boothe block Justin Smith. But Snee could not stymie McDonald in a one-on-one situation, either. Like the Wilfork plays, notice where the line of scrimmage is here (New York's 48) and how far McDonald (directly in front of Manning) has pushed Snee back.
The Giants have to figure out some way, between now and Super Bowl Sunday, to shore up their pass protection. Maybe they ask more of fullback Henry Hynoski or keep tight ends Jake Ballard and Travis Beckum in to block.
Whatever the solution, it's hard to envision anyone on the Giants' O-line stopping Wilfork one-on-one. Given Baas' issues slowing McDonald, it would not be a surprise to see New England line Wilfork up over the Giants' center on most passing plays.
That, almost certainly, will force the Giants to use Boothe or Snee to help double-team Wilfork. How well New York does on offense will then depend on the other three offensive linemen holding their blocks and the backs/tight ends picking up any blitzers.
But it can be done. The Giants allowed just one sack each to the Packers and Falcons.
How? Well, first and foremost, the blocking was just flat-out better in those games than it was Sunday. However, up against Atlanta's four-man front, New York had some success by using a tight end in protection.
Here's one example from that wild-card round game, with Jake Ballard on the left side of the line.
The Falcons rushed four on this play, and the Giants' protection was perfect. With some help from David Diehl, Ballard closed off Manning's blindside. Next to that duo, Boothe stood his man up.
And on the right side, Baas delivered a solid block after the snap on defensive tackle Curtis Lofton, then handed him off to Snee and Kareem McKenzie and turned his attention to John Abraham.
Manning wound up throwing a touchdown pass down the middle on the play. When the Giants' QB has time, he's playing at an extremely high level right now — as are his talented wide receivers.
This play is the blueprint for the Giants when the Patriots don't blitz. At least one or two linemen will have to hold up in man-on-man situations, but if that happens, New York can drop extra help in for whichever player is responsible for Wilfork.
Keeping the Patriots' big DT from bull-rushing into the backfield will be a major point of emphasis for the Giants. It won't be easy to do, and New York will need to be a lot better up front than it was against San Francisco to have any hope.
[...] Monday: Vince Wilfork vs. Giants' O-line [...]
[...] Monday: Vince Wilfork vs. Giants' O-line [...]
[...] Monday: Vince Wilfork vs. Giants' O-line [...]
[...] Monday: Vince Wilfork vs. Giants' O-line [...]
[...] Monday: Vince Wilfork vs. Giants' O-line [...]
[...] Monday: Vince Wilfork vs. Giants' O-line [...]


text:
July 27, 2006
Statement of
Dr. George P. Nanos
Associate Director
Research and Development Enterprise,
Defense Threat Reduction Agency
Before the
Subcommittee on Terrorism, Technology and Homeland Security
Committee on the Judiciary
United States Senate
Concerning U.S. Nuclear Detection Capabilities
July 27, 2006
Mr. Chairman, it is an honor to be here today to address the Defense Threat Reduction Agency's (DTRA) Radiation Detection program. I'm Dr. Pete Nanos, Associate Director for Research and Development (R&D) at the DTRA. As such, I am responsible for combating Weapons of Mass Destruction (WMD) by providing R&D capabilities to reduce, eliminate, counter, and defeat the threat of WMD and mitigate its effects.
DTRA is a combat support agency which means that the warfighter in the field is our customer and primary focus. Since its establishment in 1998, DTRA has been providing capabilities for the Department of Defense's (DoD) nonproliferation, counterproliferation, and consequence management programs; the three pillars of the President's National Strategy To Combat WMD. The agency's mission covers the complete WMD threat spectrum - chemical, biological, radiological, nuclear, and high yield explosives.
The President stated in the March 2006 National Security Strategy of the United States of America, "There are few greater threats than a terrorist attack with WMD." Radical terrorist groups have repeatedly stated their intention to seek and use weapons of mass destruction. The evidence indicates that they are aggressively pursuing chemical, biological, radiological, and nuclear materials to make good on those threats. We also face potential proliferation and direct military threats from WMD possessed by nations hostile to the United States.
The National Security Strategy provides the overarching guidance for combating WMD. This strategy states that countering the proliferation of WMD requires a comprehensive strategy involving strengthened nonproliferation efforts to deny these weapons and related expertise to those seeking them; proactive counterproliferation efforts to defend against, defeat and eliminate WMD and their means of delivery before they are unleashed; and effective consequence management to respond to the effects of WMD use, either by terrorists or nation-states.
The combating WMD strategy is developed in more detail by the National Defense Strategy, the National Military Strategy, and the National Strategy to Combat WMD, all reflecting the framework of the National Security Strategy.
Further, the Report of the 2006 Quadrennial Defense Review (QDR) provides additional emphasis on transforming capabilities to combat WMD. The QDR and other national guidance state the need for the following types of capabilities:
1) "Capabilities to locate, tag and track WMD, their delivery systems and related materials, including the means to move such items";
2) "Capabilities to detect fissile materials such as nuclear devices at stand-off ranges";
3) "Interdiction capabilities to stop air, maritime, and ground shipments of WMD, their delivery systems and related materials";
4) "Persistent surveillance over wide areas to locate WMD capabilities or hostile forces".
The Department of Homeland Security Domestic Nuclear Detection Office (DHS/DNDO), with personnel from several Federal departments and agencies, has drafted an enhanced global nuclear detection architecture in which the Secretary of Defense retains responsibility for implementing DoD requirements within and outside the United States in accordance with the Domestic Nuclear Detection NSPD-43/HSPD-14. DoD is working with the other Federal departments specifically mentioned in NSPD-43/HSPD-14 to draft a Memorandum of Agreement to promote an integrated national research and development effort in nuclear and radiological detection. The DTRA Radiation Detection program will support implementation of the DoD components of the global nuclear detection architecture and will complement the radiation detection programs of the Domestic Nuclear Detection Office (DNDO) and the Department of Energy's National Nuclear Security Agency (DOE/NNSA). Our DoD-specific missions require mobile and transportable detection systems, some mounted on military vehicles, operated by Soldiers, Sailors, Airmen and Marines, and employed in fluid, potentially hostile situations. In contrast, a large portion of the DHS/DNDO mission is keyed to supporting the mission of Customs and Border Protection (CBP) aimed at border security, ports, portals, and cargo. Long dwell detection in transit, cargo inspection during border crossings, and vehicular monitoring at ports and borders are high priority DHS/DNDO missions. Unlike DoD missions, these tend towards fixed or controllable site installations in a relatively controlled environment. DOE conducts long term research to provide advance capabilities for nuclear detection and monitoring for the national and homeland security communities. It also supports near term applications for cooperative international efforts in safeguards and international security, in conjunction with its policy program. Many of the resulting technologies can be leveraged to support both DoD and DHS/DNDO missions. Military conflict (hostile environments) is not a part of DHS/DNDO or DOE/NNSA mission areas but is a key consideration for developing advanced capabilities for DoD. The ability to maintain operational tempo, the requirement to continue and complete the mission, and the need to operate at greater distances and shorter times are key DoD drivers. A key to the successful detection of threat materials is characterizing the radiation background in any operational theater. DoD must have the capability for rapid detection, identification, tracking, and interdiction of radiological items transiting that theater and the subsequent real time characterization of the theater following a nuclear or radiological incident, thus altering plans and movements as necessary to complete the mission. DoD must be able to find, fix, and finish potential adversaries, denying or taking away their potential threat to the United States.
All the respective Federal departments and agencies must work together to achieve a multi-layered defense strategy to protect the U.S. from a nuclear or radiological attack. I did not intend to imply no overlap between the missions of DTRA, DHS/DNDO, and DOE/NNSA in my earlier comments on contrasting DoD mission space with that of other Federal departments. DHS/DNDO is interested in mounting detectors onto vehicles for border monitoring activities geared more toward the continental United States (CONUS) and the domestic layers of the nuclear detection architecture including ports of entry; air, ground, and maritime pathways at unattended borders and coastlines; and regional, state, and local countermeasures. DNDO is also oriented towards cooperative international efforts and efforts at foreign ports in partnership with DOE/NNSA and CBP. Similarly, DoD needs to consider military installation protection globally, to include CONUS locations, and everyone is interested in larger standoff detection. We have frequent formal, informal, and semi-formal discussions with our interagency partners to de-conflict program activities, actively cooperate in testing or development of key technologies, and review each other's proposals, programs, and activities to ensure that we do not duplicate efforts. The goal is a coherent, coordinated national program to ensure that all national mission areas are met.
The Department has focused on the WMD challenge for many years now and we have been making steady progress in expanding our capabilities to combat WMD, and in building interagency partnerships. The QDR continues this momentum by providing specific near-term direction and longer-term guidance on capabilities and the required investments.
Mr. Chairman, this concludes my remarks. I would be pleased to respond to your questions.


text:
Results 1 to 5 of 5
Hey everyone, I've ran into an issue while transferring old pictures to my Lumia 920. With my old Focus it would sort all my pictures by date perfectly. This time with the new phone, it puts a lot of pictures under January 2013. I deleted it from the phone and through PC, same problem. Anyone else run into this problem? Any solutions?
Holy this really pissed me off
I had this issue with my old photos from my N9/N8 and dug into try and fix it.
You need to update the EXIF information of the photo cause it seems to use a flag called Create Date to order the files. Well that's the one inconsistency. Anyways, to get it all I decided to update all the pictures EXIF date informations to be the same date. It seem Date/Time Original exists everywhere but is not used by WP8 to sort so I used that date which was still good to update everydate possible in the picture exif info.
I used a command line tool called exiftool ExifTool by Phil Harvey
and used this command to update all dates information in the EXIF
exiftool "-datetimeoriginal>Alldates" *.jpg
And now my pictures going back to Aug 2011 are properly grouped and sorted. - 01-10-2013, 04:49 PM #3
cool thanks i'll check that out.
I tried that tool and it still doesn't work for my photos. :/Last edited by Trader05; 01-10-2013 at 08:00 PM.
I tried it again and it worked for most photos...thanks!
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text:
Also available in standard sizes
Was £21.00
Now £10.50
Now £6.30
70% Off
Save a total of £14.70
Standard Delivery
Click & Collect
International Delivery
Big and tall turquoise double tram striped pique polo shirt
Item No.0900108128
This turquoise polo shirt from Maine New England is made from soft pique cotton and has a navy and white double tram stripe design. Also available in standard sizes.
Also available in this range
- Model height is 185cm/6'1"
- Model chest size: 38"/97cm
- Model is wearing size small
- 100% cotton
- Regular fit
- Polo neck
- Double tram stripe design
- Three button placket
- Machine washable
- Tumble dry safe
Debenhams is happy to exchange or refund your purchase within 28 days providing the goods are in a fully resaleable condition (including tags) and not within the exclusion policy*. This policy does not affect your statutory rights. You can return unwanted items either by visiting your local store (the fastest way to get a refund), by arranging a courier collection or returning by post. Exclusions apply to selected products. For instructions on how to return products and information on Debenhams refund policy visit the returns and refunds section of the website.


text:
Making the most of IT asset management
Choosing a data center asset management tool depends on how the infrastructure functions, the mix of hardware and software in action and more factors.
Safety rules to clean up a messy data center
Ensuring that your data center runs safely can be hard work, but upholding maintenance best practices is imperative. Adopt and build upon these rules.
What's holding back DCIM software?
There is a lot of hype surrounding DCIM monitoring tools, but DCIM has inherent limitations. Here are the top five challenges hampering DCIM adoption.
Linux basics for the Windows server admin: Editing with vi or vim
New Linux administrators will need to master a core cadre of vi (or vim) text editor commands. Start with the basics, then explore other vi commands.
What future server racks look like
Optical interconnects turn server designs inside out. The use of silicon photonics will send optical signals on a long-distance journey without loss.
How to protect RHEL HA from file system errors
You have a working cluster, now what? Red Hat's GFS2 will help you avoid file system corruption. Learn how to mount the default cluster file system.
Demystifying ITIL 2011 service management
Promised cost savings, alignment with business, and operational efficiency are encouraging more organizations to take up ITIL service management.
Ask a colo: Colocation or cloud?
Colocation facilities have a reputation as just a roof over your servers' head, so why move into colocation space when you could go straight to cloud?
Learning to work with SELinux
Rather than giving up on SELinux and allowing permissions you shouldn't, use these SELinux commands to troubleshoot problems.
The values and drawbacks of engineering your own server
Would you approach buying a server in the same way you buy a laptop? Open-source hardware is placing the spotlight on ODM server manufacturers.
Modular data center offers relief for stressed IT shops
With the sometimes unpredictable nature of business IT, a modular data center could fit right into IT's plans -- if you know which kind to pick.
Server features that prevent failures
A new generation of processors uses sophisticated combinations of techniques to prevent server failures in enterprise data centers.
Performance enhancement storage: Enterprises employ SSD systems
Companies weigh SSDs' increased performance against higher costs as they attempt to cope with rising storage requirements.
When DR isn't enough, try business continuity
DR won't prevent downtime, but the choice for high-uptime IT shops isn't business continuity vs. disaster recovery, it's how to incorporate both.
Set up array-based snapshots to work smarter, not harder
Choices you make in configuring SAN snapshots and array disks will affect your storage capacity and performance, so choose wisely to avoid file loss.
Setting up a highly available Apache web service in six steps
When a Red Hat cluster goes into production, you can protect it by configuring a supported high-availability service. Here's how.
Remote employees to IT: This isn't working out
With multiple data center locations, enterprises must design new platforms to provide access to remote employees instead of centralizing technology.
The flash memory proposition for data center storage
Flash-based enterprise storage systems offer read-cycle speeds that databases crave, but consider write-cycle and connectivity options before you buy.
Linux basics for the Windows server admin: Service administration
To manage Linux servers, administrators need a set of basic commands to view and start processes, as well as utilities that make life a little easier.
How to shop columnar database appliances
Four main vendors offer columnar database appliances for business analytics and big data processing. Each product has its own approach and tradeoffs.
Speed up Linux server performance with a RAM file system
A RAM file system isn't real, but its benefits are: It allows Linux servers to store temporary files without taking up disk space.
Matching a server management tool to the data center
Homogeneous system management tools provide excruciating detail on servers, but in some circumstances, heterogeneous tools are a better choice.
Knowing when and how to update your server fleet
Server refresh cycles can be more nuanced than a rip and replace of used servers. Consider these options for longer server lifecycles.
Linux basics for the Windows server admin: Killing a process
When a process fails, go for the kill. You know how to start and stop Linux services, but what happens when you need to kill one?


text:
October 20, 2013
I got this torch as a spare for my son to take on a weekend camping trip, it works well but didn't get 5 stars as one of the grips fell off.
October 16, 2013
Very easy to use. doesnt meed batteries which is a plus. very bright led bulbs.
August 22, 2013
We were given one of these as a present last christmas, but we like it so much we have purchased 2 more for around the house. it gives a good light, and on one wind up, it lasts a long time. what more could i wish for.
August 12, 2013
This needs no batteries! wonderful!
March 09, 2013
I took this on my travels, very useful.
This does not affect your statutory rights
For full terms and conditions please see our Delivery & Returns policy


text:
I stay in 5 hotels a week on average. I am always looking for the best bang for the buck. This hotel is clean and comfortable and is a great value for the location and condition. The rooms are clean, the staff is very nice, there is free wifi and free long distance calls. I would definantely stay here again.
- Also Known As:
- Rodeway Inn Oklahoma City
- Oklahoma City Rodeway Inn
- Reservation Options:
- TripAdvisor is proud to partner with Expedia, Priceline, Travelocity, Booking.com, Choice Hotels, Tingo, TripOnline SA, Orbitz, Hotels.com, Venere and Agoda so you can book your Rodeway Inn & Suites reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.


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This is an NIH subline of C57BL/6. It was separated from C57BL/6J in 1951. Five SNP differences have been identified that distinguish C57BL/6J from C57BL/6ByJ and C57BL/6NJ. This strain does not have the deletion in the Nnt gene that has been found in the C57BL/6J strain (Stock No. 000664). |
Former Names C57BL/6NCrJ (Changed: 26-APR-05 ) Type Inbred Strain; Additional information on Inbred Strains. Visit our online Nomenclature tutorial. Mating System Inbred x Inbred (Female x Male) 01-MAR-06 Breeding Considerations This strain is a good breeder. Species laboratory mouse Generation F5pF13 (17-SEP-12)
Generation Definitions
View larger imageAppearance
Related Genotype: a/aImportant Note
This strain is homozygous for Crb1rd8, the retinal degeneration 8 mutation. Photoreceptor degeneration is observed in spots, caused by retinal folds and pseudorosettes, found in the fundus of the eye.Description
This is an NIH subline of C57BL/6. It was separated from C57BL/6J in 1951. 5 SNP differences have been identified that distinguish C57BL/6J from C57BL/6ByJ and C57BL/6NJ. Both C57BL/6ByJ and C57BL/6NJ type as follows: 08-015199792-M (rs3709624) is C; 11-004367508-M (rs3659787) is A; 13-041017317-M (rs3722313) is C; 15-057561875-M (rs3702158) is G; 19-049914266-M (rs3724876) is T. C57BL/6J types as follows: 08-015199792-M is T; 11-004367508-M is G; 13-041017317-M is T; 15-057561875-M is A; 19-049914266-M is G (Petkov and Wiles 2005.) This strain does not have the deletion in the Nnt gene that has been found in the C57BL/6J strain (Stock No. 000664). C57BL/6NJ mice are homozygous for Cyfip2M1N, a spontaneous mutation in the cytoplasmic FMR1 interacting protein 2 that results in an amino acid substitution of phenylalanine for serine at position 968 (S968F). The mutation is found in all C57BL/6N substrains but is not present in the C57BL/6J strain or substrains. The mutation results in 45% lower acute response to cocaine as measured by locomotor hyperactivity.Development
In 1951 C57BL/6J, then at generation F32, were sent from The Jackson Laboratory to The National Institute of Health where they were maintained via sibling mating for decades. In 1980 this subline reached F126 and in 1984 embryos were cryopreserved at the NIH cryopreservation facility. In approximately 1994 some of these embryos were thawed and maintained via sibling mating and this subline was referred to as B6(e84) to specify that it derived from the embryos frozen in 1984. In September and October of 1997 a new set of embryos were cryopreserved from this thawed line by backcrossing +F6 females to their +F5 fathers. In 2005 some of these embryos frozen in 1997 were sent to The Jackson Laboratory where they were thawed and gave rise to C57BL/6NJ. Thus, C57BL/6NJ is devoid of mutations that may have arisen in any C57BL/6N sublines that remained on the shelf after the 1984 freeze. The embryos received by The Jackson Laboratory were thawed, the colony expanded, and re-frozen immediately. This strain is maintained with frequent replenishment from this frozen stock in order to arrest genetic drift.
C57BL Strains
000665 C57BL/10J 003752 C57BL/10ScNJ 000476 C57BL/10ScSnJ 000666 C57BL/10SnJ 001822 C57BL/10SxJ 001197 C57BL/10WtRkJ 000663 C57BL/6By 001139 C57BL/6ByJ 009123 C57BL/6HaJ 000664 C57BL/6J 000924 C57BL/6JEiJ View C57BL Strains (11 strains)Strains carrying Crb1rd8 allele
005711 B6.129P2-Prkcqtm1Litt/J 004852 B6;129-Crb1rd8/J 001633 CXB12/HiAJ 000352 CXB2/ByJ 000353 CXB3/ByJ 000355 CXB5/ByJ 001630 CXB9/HiAJ 003392 STOCK Crb1rd8/J View Strains carrying Crb1rd8 (8 strains)
JAX® NOTES, Fall 2008; 511. Influence of Nnt alleles on DIO in C57BL/6 JAX® Mice.
JAX® NOTES, Winter 2008; 512. New resource illustrates divergence of C57BL/6 laboratory mouse substrains.
Request a copy of our Divergence of C57BL/6 Laboratory Mouse poster.
Sequence data is available from the Mouse Genomes Project at the Wellcome Trust Sanger Institute
View Phenotypic DataPhenotypic DataBody Weight Information - JAX® Mice Strain C57BL/6NJ (005304)Mouse Phenome Database
(This chart reflects the typical correlation between body weight and age for mice maintained in production colonies at The Jackson Laboratory.)
Festing Inbred Strain Characteristics: C57BL
View Related Disease (OMIM) TermsRelated Disease (OMIM) Terms provided by MGI
- Potential model based on gene homology relationships. Phenotypic similarity to the human disease has not been tested. Leber Congenital Amaurosis 8; LCA8 (CRB1)
Pigmented Paravenous Chorioretinal Atrophy; PPCRA (CRB1)
Retinitis Pigmentosa 12; RP12 (CRB1)
View Research ApplicationsResearch ApplicationsThis mouse can be used to support research in many areas including:
Crb1rd8 relatedResearch Tools
General Purpose
Cell Biology Research
Defects in Cell Adhesion Molecules
Developmental Biology Research
Eye Defects
Sensorineural Research
Retinal Degeneration
Allele Symbol | Crb1rd8 | ||
Allele Name | retinal degeneration 8 | ||
Allele Type | Spontaneous | ||
Common Name(s) | Rd8-; nmf144; | ||
Strain of Origin | C57BL/6J | ||
Gene Symbol and Name | Crb1, crumbs homolog 1 (Drosophila) | ||
Chromosome | 1 | ||
Gene Common Name(s) | 7530426H14Rik; A930008G09Rik; LCA8; RIKEN cDNA 7530426H14 gene; RIKEN cDNA A930008G09 gene; RP12; | ||
Molecular Note | The mutation in the rd8 mouse has been identified as a single base deletion in the Crb1 gene. This deletion causes a frame shift and a premature stop codon that truncates the transmembrane and cytoplasmic domain of the protein. [MGI Ref ID J:85459] | ||
Allele Symbol | Cyfip2M1N | ||
Allele Name | mutation 1, National Institutes of Health | ||
Allele Type | Spontaneous | ||
Common Name(s) | Cyfip2B6N; | ||
Strain of Origin | C57BL/6N | ||
Gene Symbol and Name | Cyfip2, cytoplasmic FMR1 interacting protein 2 | ||
Chromosome | 11 | ||
Gene Common Name(s) | 1500004I01Rik; 6430511D02Rik; AA930218; AU022376; PIR121; RIKEN cDNA 1500004I01 gene; RIKEN cDNA 6430511D02 gene; expressed sequence AA930218; expressed sequence AU022376; mKIAA1168; | ||
Molecular Note | An G to A mutation at 46,036,117 base pair (bp) of chromosome 11 (mm9) occured between 1961 and 1974 in the C57BL/6N strain that resulted in the amino acid substitution of phenylalanine for serine at position 968 (S968F). This mutation is found in all C57BL/6N substrains (C57BL/6NCrl, C57BL/6NTac and C57BL/6NJ) but is not present in the C57BL/6J strain or substrains (C57BL/6Ei, C57BL/6EiJ, C57BL/6ByJ and C57BL/6By). The mutation destabilizes the protein leading to decreased half-life. [MGI Ref ID J:203183] |
Genotyping Protocols
Nnt,Separated MCA
Nnt, Separated PCR
Helpful Links
Genotyping resources and troubleshooting
Keane TM; Goodstadt L; Danecek P; White MA; Wong K; Yalcin B; Heger A; Agam A; Slater G; Goodson M; Furlotte NA; Eskin E; Nellaker C; Whitley H; Cleak J; Janowitz D; Hernandez-Pliego P; Edwards A; Belgard TG; Oliver PL; McIntyre RE; Bhomra A; Nicod J; Gan X; Yuan W; van der Weyden L; Steward CA; Bala S; Stalker J; Mott R; Durbin R; Jackson IJ; Czechanski A; Guerra-Assuncao JA; Donahue LR; Reinholdt LG; Payseur BA; Ponting CP; Birney E; Flint J; Adams DJ. 2011. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 477(7364):289-94. [PubMed: 21921910] [MGI Ref ID J:177037]
Kumar V; Kim K; Joseph C; Kourrich S; Yoo SH; Huang HC; Vitaterna MH; de Villena FP; Churchill G; Bonci A; Takahashi JS. 2013. C57BL/6N mutation in Cytoplasmic FMRP interacting protein 2 regulates cocaine response. Science 342(6165):1508-12. [PubMed: 24357318] [MGI Ref ID J:203183]
Toye AA; Lippiat JD; Proks P; Shimomura K; Bentley L; Hugill A; Mijat V; Goldsworthy M; Moir L; Haynes A; Quarterman J; Freeman HC; Ashcroft FM; Cox RD. 2005. A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice. Diabetologia 48(4):675-86. [PubMed: 15729571] [MGI Ref ID J:106692]
Crb1rd8 relatedAleman TS; Cideciyan AV; Aguirre GK; Huang WC; Mullins CL; Roman AJ; Sumaroka A; Olivares MB; Tsai FF; Schwartz SB; Vandenberghe LH; Limberis MP; Stone EM; Bell P; Wilson JM; Jacobson SG. 2011. Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model. Invest Ophthalmol Vis Sci 52(9):6898-910. [PubMed: 21757580] [MGI Ref ID J:181396]
Barber AC; Hippert C; Duran Y; West EL; Bainbridge JW; Warre-Cornish K; Luhmann UF; Lakowski J; Sowden JC; Ali RR; Pearson RA. 2013. Repair of the degenerate retina by photoreceptor transplantation. Proc Natl Acad Sci U S A 110(1):354-9. [PubMed: 23248312] [MGI Ref ID J:192521]
Chang B; Hawes NL; Hurd RE; Davisson MT; Nusinowitz S; Heckenlively JR. 2002. Retinal degeneration mutants in the mouse. Vision Res 42(4):517-25. [PubMed: 11853768] [MGI Ref ID J:75095]
Chang B; Hawes NL; Hurd RE; Wang J; Howell D; Davisson MT; Roderick TH; Nusinowitz S; Heckenlively JR. 2005. Mouse models of ocular diseases. Vis Neurosci 22(5):587-93. [PubMed: 16332269] [MGI Ref ID J:156373]
Chang B; Hurd R; Wang J; Nishina P. 2013. Survey of common eye diseases in laboratory mouse strains. Invest Ophthalmol Vis Sci 54(7):4974-81. [PubMed: 23800770] [MGI Ref ID J:198916]
Chen Y; Sawada O; Kohno H; Le YZ; Subauste C; Maeda T; Maeda A. 2013. Autophagy protects the retina from light-induced degeneration. J Biol Chem 288(11):7506-18. [PubMed: 23341467] [MGI Ref ID J:196891]
Lakowski J; Baron M; Bainbridge J; Barber AC; Pearson RA; Ali RR; Sowden JC. 2010. Cone and rod photoreceptor transplantation in models of the childhood retinopathy Leber congenital amaurosis using flow-sorted Crx-positive donor cells. Hum Mol Genet :. [PubMed: 20858907] [MGI Ref ID J:165574]
Mattapallil MJ; Wawrousek EF; Chan CC; Zhao H; Roychoudhury J; Ferguson TA; Caspi RR. 2012. The rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes. Invest Ophthalmol Vis Sci :. [PubMed: 22447858] [MGI Ref ID J:182353]
Mehalow AK; Kameya S; Smith RS; Hawes NL; Denegre JM; Young JA; Bechtold L; Haider NB; Tepass U; Heckenlively JR; Chang B; Naggert JK; Nishina PM. 2003. CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina. Hum Mol Genet 12(17):2179-89. [PubMed: 12915475] [MGI Ref ID J:85459]
Perkins GA; Scott R; Perez A; Ellisman MH; Johnson JE; Fox DA. 2012. Bcl-xL-mediated remodeling of rod and cone synaptic mitochondria after postnatal lead exposure: electron microscopy, tomography and oxygen consumption. Mol Vis 18:3029-48. [PubMed: 23288995] [MGI Ref ID J:192587]
Won J; Shi LY; Hicks W; Wang J; Hurd R; Naggert JK; Chang B; Nishina PM. 2011. Mouse model resources for vision research. J Ophthalmol 2011:391384. [PubMed: 21052544] [MGI Ref ID J:166679]
Zhang N; Kolesnikov AV; Jastrzebska B; Mustafi D; Sawada O; Maeda T; Genoud C; Engel A; Kefalov VJ; Palczewski K. 2013. Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization. J Clin Invest 123(1):121-37. [PubMed: 23221340] [MGI Ref ID J:194158]
Animal Health Reports
Room Number AX5
Room Number AX6
Room Number RB07
Colony Maintenance
Mating System Inbred x Inbred (Female x Male) 01-MAR-06 Breeding Considerations This strain is a good breeder. Diet Information LabDiet® 5K52/5K67
Pricing for USA, Canada and Mexico shipping destinations |
Weeks of Age Price per mouse (US dollars $) Gender 3 weeks $19.85 Female $18.15 Male 4 weeks $19.85 Female $18.15 Male 5 weeks $21.25 Female $19.85 Male 6 weeks $21.25 Female $19.85 Male 7 weeks $24.35 Female $23.95 Male 8 weeks $24.85 Female $23.95 Male 9 weeks $24.85 Female $23.95 Male 10 weeks $29.65 Female $29.95 Male 11 weeks $29.65 Female $29.95 Male 12 weeks $30.50 Female $29.95 Male Standard Supply
Level 2. Up to 100 mice. Larger quantities or custom orders arranged upon request.
Supply Notes
Volume pricing is available for this strain. View our Volume Pricing Program for information.- This strain is available from both the Bar Harbor, Maine and Sacramento, Calif. facilities.
- Shipped at a specific age in weeks. Mice at a precise age in days, littermates and retired breeders are also available.
Pricing for International shipping destinations |
Weeks of Age Price per mouse (US dollars $) Gender 3 weeks $25.90 Female $23.60 Male 4 weeks $25.90 Female $23.60 Male 5 weeks $27.70 Female $25.90 Male 6 weeks $27.70 Female $25.90 Male 7 weeks $31.70 Female $31.20 Male 8 weeks $32.40 Female $31.20 Male 9 weeks $32.40 Female $31.20 Male 10 weeks $38.60 Female $39.00 Male 11 weeks $38.60 Female $39.00 Male 12 weeks $39.70 Female $39.00 Male Standard Supply
Level 2. Up to 100 mice. Larger quantities or custom orders arranged upon request.
Supply Notes
- Shipped at a specific age in weeks. Mice at a precise age in days, littermates and retired breeders are also available.
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Marinade and Dipping Sauce, Sweet Ginger Teriyaki, 6 Pack, 12.7 fl oz (375 ml), From East-West Specialty Sauces
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Coverage: CBS
4:05 PM ET, November 11, 2012
CenturyLink Field, Seattle, WA
SEATTLE, WA - NOVEMBER 11: Quarterback Tim Tebow #15 of the New York Jets passes against the Seattle Seahawks at CenturyLink Field on November 11, 2012 in Seattle, Washington. The Seahawks defeated the Jets 28-7. (Photo by Otto Greule Jr/Getty Images)


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Route 8 Corridor Study |
Montgomery County |
Project at a Glance
Summer 2012
Est Completion Date
Spring 2013
Jay Guy
A study is taking place on a nine-mile section of Route 8 from Interstate 81 at exit 114 to Route 863 (River Lane NW) in Montgomery County and the Town of Christiansburg.
The study will focus on operations, access management and safety. It will also develop alternatives and recommendations for transportation
improvements based on traffic projections through the year 2035.
Citizen Information Meetings
Citizen information meetings were held on Wednesday, Jan. 23 and Tuesday, April 9 in Riner to gather input from citizens who live and work in the area to include in the study. The presentations given at the meetings are available at the link below.
Any comments on the presentations must be received by April 19, 2013. You may send your comments to Jay Guy, at PO Box 3071, Salem, VA 24153 or via email to firstname.lastname@example.com. Please use "Route 8 Study Comment" in the subject line.


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It is okay to be at a place of struggle. Struggle is just another word for growth. Even the most evolved beings find themselves in a place of struggle now and then. In fact, struggle is a sure sign to them that they are expanding; it is their indication of real and important progress. The only one who doesn't struggle is the one who doesn't grow. So if you are struggling right now, see it as a terrific sign — celebrate your struggle.
— (via kvtes)(Source: onlinecounsellingcollege, via kvtes)


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Tampa Bay's Real. Raw. Radio.
Hi, (not you?) | Member Center | Sign Out
Posted: 6:22 a.m. Tuesday, March 26, 2013
Last night, Discovery aired KKK: Beneath the Hood, a documentary that purported to offer previously unavailable access to various Ku Klux Klan chapters. Such unveiling feels like an act of desperation for a dying breed of people who are irrationally fixated on racial purity and white supremacy while claiming that they don't hate anyone. Bigotry is alive, of course, but I wonder how well it is when even the Klan is too cowardly to own up to its hatred. (Note: Hamilton Nolan's "My Kasual Kountry Weekend With the Knights of the Ku Klux Klan" Gawker story from last year touches on this very phenomenon.)
In the clip above, they hand out sandwiches and various household items in Missouri to show what good guys they are. Basically, they are preying on the impoverished to reseed their losing agenda. Great guys. Nonetheless, their plan seems to work — the few people that turn out for the event, including the police, seem delighted. To put the philosophy of the Traditionalist American Knights of the Ku Klux Klan into perspective, Imperial Wizard Frank Ancona explains to the cops, "You got different types of birds like crows, sparrows. They stay with their own kind. But they're all birds. So that's kind of our view on it."
The organization that takes its social cues from birds. Maybe one day they'll figure out how to turn a twig into a tool. And then you'll be sorry that you didn't join when you had the chance.
Via: Gawker
Click Here to Watch the Video
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A new, stylish external storage solution from Brinell GmbH recently surfaced, revealing seven beautiful SSD form factor styles to choose from. Sporting USB 3.0 specs, the Brinell external SSDs offer zippy read/write speeds in UAS Turbo mode of 420/330 MB/s respectively, with prices starting from about $216 for the 120GB version to $768 USD for 500GB capacity.
High-end performance meets
Author Archives: Bryan Eley
Rechargeable BlueFlame Slingshot Bluetooth Speaker Review – It Goes Anywhere!
BlueFlame has quite the repertoire of stylish accessories for you mobile needs. One such clever device is their Slingshot wireless, water-resistant speaker. At about $119, this speaker system packs a lot of sound in a small package and can fit into other BlueFlame Slings. Simply pop the speaker unit proper out of one Sling and slip into another.
The BlueFlame
USBFever Introduces 3-Port USB Hub with Lightning Cable for iPhone and iPad
Known for inventive mobile accessories, USBFever now offers the USB to 8 Pin Lightning Cable with 3-Port USB Hub for iPhone/iPad for users wanting to make the most of their desk space. Priced at just $6.95 the mini-hub allows busy folk to charge and sync a number of devices along with iOS devices sporting a Lightning port. Get yours today!
The Nourishmat Starts Your Gardening Adventure with Ease!
Do you lack a green thumb, but like fresh vegetables? Have only a small space in your yard but want a garden? If so, the good folks at Nourishmat have a special package for you! At $64.95 for the base model, the Nourishmat comes with a weed-barrier mat with plant templates for seeds and step-by-step instructions—perfect for beginners!
It is
Sugru Is the Grown-Up Play-Dough for DIY Projects
If you've ever dabbled in small home improvement projects, wanted to fix a damaged item or just mold something to a desired shape to hold something, Sugru might be just the thing for you. Perhaps falling somewhere between ubiquitous duct tape and super glue, Sugru is a moldable, self-curing rubber that can bond to a variety of surfaces and is
Celebrate Julia Child's 101st Birthday with a Price Reduction in the Mastering the Art of French Cooking App!
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DataViz Protects and Syncs Your Passwords and Sensitive Info with Passwords Plus
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Keep a (Free) Sharp Lookout for Boats with PocketMariner's Boat Watch iOS App
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Read moreJustin Case Rechargeable iPad Battery Case Review
Power, power every where,
And my battery levels did shrink;
Power, power, every where,
Nor any electricity to drink.
With apologies to Samuel Taylor Coleridge, how often have you been going about your days busily using your iPad, only to discover the battery is getting low, and it's just not convenient or possible to plug it into a wall charger?
Start Dipping Your Cookies in Milk the Civilized Way with the Dipr
Surely one of the best known images representing the simple pleasures of childhood must be dipping cookies in milk. My sister and her friends were avid practitioners of the art, but I never took a shining to the practice myself. The whole dipping one's cookie and often fingers into milk just seemed messy and uncivilized, just too reminiscent of early
Why Settle for a Stationary Hot Tub When You Can Set Sail with the HotTug?
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Wrap Yourself in Protection with the Insect Shield Outdoor Blanket
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Satechi USB Portable Humidifier Turns Your Water Bottles into Personal Climate Contollers
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Mood O' Clock App Lets You Choose the Right Mood to Wake You Up
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HP Releases App Catalog Fix to Keep WebOS Devices Afloat
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Phoenix International Communications Working to Bring Android Apps to HP Touchpad Via Kickstarter
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xkcd's Interstellar Memes Graphic, or Stellar Distance Measured by Age of Pop Culture Phrases
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I'm just this guy, you know? I'm a CNU graduate with a degree in physics. Before starting xkcd, I worked on robots at NASA's Langley Research Center in Virginia. As of June 2007 I live
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Read more


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There's little time left, but because books make great last-minute gifts, I consulted a few retired friends for suggestions to add to my own.
There was a surprise. I didn't expect to find authors with Appalachian connections topping the list, even from a friend in Dallas.
A retired college professor, Jacque Lytle, wrote in an email, "I think I can make a recommendation for the older among us, especially women."
Jacque had just suggested this book at a meeting of her local American Association of University Women. Her choice was "Half Broke Horses" by Jeanette Walls. Walls' first book, of course, was the best-selling "The Glass Castle," about the sometimes shocking, factual recollections of her youth in the coalfields of West Virginia.
The second book, also a best-seller, focuses on her grandmother, an amazing woman who was helping her father break horses by the time she was 6. Born in 1901, she left home at 15 to teach, riding 500 miles on a pony to get a job. She became a pilot, a rancher, survived tornadoes, floods, the Great Depression and personal tragedies, all of which, Jacque wrote, "certainly make me feel a bit wimpy."
Nor was Jacque the only one to recommend books by Walls. Mason County resident Hilda Austin recommends books by Walls as well as by another author with Appalachian ties, Barbara Kingsolver.
"Kingsolver writes in such a diverse and intense way that you can't put the book down!" Hilda said in an email. "I have read all of Barbara Kingsolver's books and can't wait for her new one, too."
Wait no more. Kingsolver's new book, "Flight Behavior," is on the shelves now.
Honestly, I've never been a fan of Kingsolver's fiction until now. "Flight Behavior" changed that. I didn't want to put it down.
Her undereducated 28-year-old "hillbilly" in Tennessee manages to translate complicated scientific discussion of climate change into down-to-earth, meaningful English.
But back to friend Hilda, whose retirement part-time position is as executive director of the Mason County Area Chamber of Commerce. She had another surprise for me.


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John Farrell has confirmed to WEEI what most of us assumed: he will turn to Jon Lester in Game 1 of the ALCS.
Farrell on @WEEI: Lead off with Lester in ALCS, but wait on other part of rotation
— Rob Bradford (@bradfo) October 9, 2013
So no surprise on Lester, who was excellent for the Sox as they got off to a 1-0 lead in the ALDS. The second half of that tweet deserves some attention, though.
The 2-3 portion of Boston's playoff rotation in particular seems quite fluid between John Lackey and Clay Buchholz. Heck, with all the time between the two series, Jake Peavy could even be up for consideration after a strong performance against the Rays Tuesday night.
Are any changes going to come, though? Probably not. John Lackey wasn't terribly good against the Rays in Game 2, but it seems like the Red Sox want him pitching at home if possible, and the current setup would ensure that would happen. On the other hand, if the Sox are headed to the massive Coliseum in Oakland, it might make sense to swap him with Buchholz so that Lackey, who has allowed 1.24 homers per nine innings this year, has a bit more space to work with.


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State prosecutors are expected to file charges against three brothers arrested in connection with the kidnapping of three Cleveland women, as their families rejoice in their homecoming. Photo: Getty Images.
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One Health Continuing Education Courses
A full description of the specific CE course appears below. For further information, or if you have other questions about MLA CE courses, contact Debra Cavanaugh, firstname.lastname@example.com, 312.419.9094, x32.
CE201W Business Communications: Library Style (web-based course) |
Level: Intermediate Instructor(s): Marty Magee, Education Liaison and Nebraska Coordinator, National Network of Libraries of Medicine (NN/LM), MidContinental Region, McGoogan Library of Medicine, University of Nebraska Medical Center-Omaha, and Barbara Bower Jones, Library Advocacy Liaison and Missouri Coordinator, NN/LM, MidContinental Region, J. Otto Lottes Health Sciences Library, University of Missouri-Columbia Offered: Saturday, May 4, 8:00 a.m.12:00 p.m. (eastern time) |
How we express ourselves can be directly related to the funding we receive and how well our libraries are perceived. Writing clear, concise communiques-including white papers, business plans, grant proposals, budget justifications, and annual reports-is essential in today's fast-changing, bottom-line-driven environment. **This web-based opportunity will take place during One Health. MLA members who are not able to attend the meeting will be able to participate in live web-based version of the course. Technical requirements will be sent electronically prior to the annual meeting. |
Browse Courses by: |


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Easter Piggy Figurine by Lenox
Darling piggy helps to fill the barnyard Easter baskets. This ivory china pig figurine portrays a darling piglet dressed in bunny ears, a big green bow, and lilac plaid vest. Hand painting adds colorful pastels with pearlescent and gold accents.
- Crafted of ivory fine china
- Accented with precious gold
- Charming gift for Easter
- Height: 4 5/8"
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