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Hunting Plains Game of South Africa
This is a discussion on Hunting Plains Game of South Africa within the Hunting Africa forums, part of the Hunting Forums - Hunting in Africa category; Hi, I'm going on a plains game hunt to RSA for ten days next summer and am trying to decide ...
10-16-2009, 01:27 PM #1New Member
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Hunting Plains Game of South Africa
Hi, I'm going on a plains game hunt to RSA for ten days next summer and am trying to decide which animals to try to take. However this is my first hunt and it all is a little overwhelming. I'm hunting with JohnXSafaris, so I just wondered if anyone had an opinion on any "must hunt" animals while I'm there. Thanks
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Hi Ray I would suggest to find out which species are indigenous to the area and focus on them. But for the most part I would just enjoy the experience of the hunt.
Good luck and enjoy every moment of it.Louis Van Bergen
Spiral Horn Safaris - South Africa
Cell:+ 27 76 577 6292
10-16-2009, 02:24 PM #3AH Enthusiast
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I wholeheartedy agree with Louis. You should first look to relax and fully enjoy the sights, sounds and the overall experience you will soon be encountering. I believe that's of major importance with any hunt, anywhere.
As for me, one of the main reasons I travel and hunt in various areas is the opportunity to encounter and perhaps take the indigenous species that inhabit the area. So it goes without saying that that's what I always focus on. Besides, the search for native species gives a guy good reason to continue traveling and hunting.
Here's wishing you a great and successful hunting experience!There is only one degree of dead . . . there are many degrees of wounded
- Member of Northeast Wisconsin SCI chapter, Lifetime member of NRA,RMEF
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Since John X Safaris is know for there big kudu....it would be first on my list. The one thing that I studied a lot...was all the colorful brochures I had picked up from going to SCI conventions in my home state. There were a lot of pictures of the animals and sights to see in Africa, and it helped me picture what I might see while visiting there on vacation. And this website thanks to Jerome has a ton information on the animals in Africa, how to tell a male and female apart, habits and how to judge a immature from a mature animal. Look under the Hunter Forum page and search the information out. I assure you Jerome has done his homework.
I always suggest that in addition to the high-profile antelopes every first-timer goes after, such as kudu and gemsbok, you be sure to take the animals that are indigenous only to where you are hunting. In South Africa, that would include bontebok, blesbok, black wildebeest, southern mountain reedbuck, Cape bushbck, Cape grysbok, etc.
Bill Quimby
10-17-2009, 08:06 PM #6New Member
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i made my first trip to namibia this year. i hunted oryx, blue wildebeest, warthog, red hartebeest, and springbok. next trip, i'll go for black wildebeest and blesbok for sure, possibly kudu. for some wierd reason i wasn't into the kudu hunt that much. i had a beauty at less than 50 yards but didnt have the interest. i enjoyed the wildebeest, oryx, and hartebeest the most. those 3 made the trip for me.
10-18-2009, 05:23 AM #7AH Enthusiast
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...All the suggestions stated above are great. You may want to add a Impala & Warthog to the list. Go there & live Africa for all its worth. Those memories are just as important as the animals you hunt. It's an experience you will never forget! Like Enysse stated there is a ton of information on this website check it out, but if you can't find something don't be afraid to start a link as there are some mighty knowledgeable people out here who are more than willing to respond to your questions!!
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This sterling silver ring offers bold style. Featuring 12k green and rose gold leaves, this band is simply outstanding. Wear this eye-catching ring with a new watch.
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subset: commoncrawl


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The first quarter of my last year in ICA is almost up, but I know I've still got a long way to go this school year.
The first of a series of late posts from our Christmas Break trip to Dubai.
A man with his camel! Camels are the cutest, they really stop and smile at your camera. :)


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■ Find me on Twitter or Facebook or see my portfolio here
Prior to working as a visual journalist at the Naples Daily News, Greg Kahn worked as a photographer the Independent Tribune in Concord, N.C., after a stint at his hometown newspaper in Wakefield, R.I.
Greg started his photography career as one of 10 recipients of a weeklong trip studying under National Geographic photographers during the North American Nature Photography Annual Summit in San Diego.
He is a magna cum laude graduate of George Washington University with a Bachelor of Arts degree in visual communications with concentrations in photography and graphic design. During his senior year, Greg volunteered at the National Geographic magazine.
Greg recently garnered numerous awards, including the 2008 & 2009 National Monthly Clip Contest Photographer of the Year and the 2010 Best of Photography small markets Photojournalist of the Year.
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An Pierle and White Velvet at Festivals
White Velvet suggests, something beautiful and cold ; something dazzling and underground ; innocence and experience - a cross between Snow White and Nico. White Velvet is also the third album from a very special artist who has successfully thrived in the cultural pop otherworld of Europe, without quite breaking through in the UK or America. There have been hints and moments, such as Time Out enthusing about An Pierle and co-songwriter and producer Koen Gisen's twisted, fragile pop in a strange, black pearl or Q Magazine concluding, huge in Ghent - the world may follow suit. Read more about An Pierlé & White Velvet on Last.fm.
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237 High Street
Middletown, CT 06459
About Wesleyan University
- Year of Foundation 1831
- Size of Campus 240 Acres
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- Calendar Type Semester
- Undergraduate Population 2,764
- Women % / Men % / Out of state 50% 50% 92% OUS
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- Selectivity of the Intuition Most selective
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Reference: Wesleyan University
Wesleyan University is known for the excellence of its academic and co-curricular programs. More than 2,700 undergraduates and some 200 graduate students from around the world pursue their classroom studies, research projects, and co-curricular interests in ways that are demanding and intensely rewarding. Here, on a beautiful campus overlooking the Connecticut River, students learn to do productive and innovative work that makes a positive difference in the world that's what Wesleyan is about.
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- Other general policies class attendance policies set by individual instructors, honor code, hazing prohibited
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Conference aims to sharpen the tools of manufacturing
Registration is now for the WBF 2011 North American Conference, which will focus on the manufacturing processes of the industry.
WBF, the Organization for Production Technology, has announced that registration is open for the 2011 North American Conference, "Sharpening the Tools of Manufacturing," to be held May 23-25 at the University of Delaware Clayton Hall Conference Center in Newark, Delaware.
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Why ads?Please enter a valid mileage
Curious about the newer model? Check out the 2014 Ford F150 Super Cab
By KBB.com Editors
KBB Expert Rating: 8.2
Claiming the title as America's best-selling full-size pickup for 35 years running is nothing to sneeze at, which is why the 2013 Ford F-150 strikes such awe in its owners and trepidation in its rivals. With a string of modern engines, including a turbocharged V6, and the latest in transmission and 4x4 mechanical componentry, the F-150 shows it isn't resting on its laurels. With an eye on the big jobs only a big truck can do, Ford builds an F-150 for just about every customer, satisfying needs from the dirtiest construction worker to the country-club set trailering their prize horses to show. Equally impressive are the F-150's class-leading capabilities, fuel economy and resale figures.
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Every version of the F-150 we tested was devoid of a rough ride, with no shudder or hopping over rough or unpaved roads and a level of quiet unheard of (no pun intended) in a full-size pickup. Each version also provided ample power, with the least-liked engine being the base V6 and the most appreciated being the new twin-turbocharged EcoBoost V6. Thanks to the F-150's electric power-assisted steering (EPAS), we experienced a level of steering feel and control that belied the big Ford's size and heft. Perhaps most impressive was the towing demonstration in which we hauled 20-foot trailers with absolutely zero drama, thanks in large part to the pickup's trailer sway control, rearview camera and integrated trailer-brake controller.TAILGATE STEP
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3.7-liter V6
302 horsepower @ 6,500 rpm
278 lb-ft of torque @ 4,000 rpm
EPA city/highway fuel economy: 17/23 mpg (2WD), 16/21 mpg (4WD), 12/17 mpg (2WD, E85), 11/15 mpg (4WD, E85)
3.5-liter twin-turbocharged V6
365 horsepower @ 5,000 rpm
420 lb-ft of torque @ 2,500 rpm
EPA city/highway fuel economy: 16/22 mpg (2WD), 15/21 mpg (4WD)
5.0-liter V8
360 horsepower @ 5,500 rpm
380 lb-ft of torque @ 4,250
EPA city/high fuel economy: 15/21 mpg (2WD), 14/19 mpg (4WD), 11/15 mpg (2WD, E85), 10/14 mpg (4WD, E85)
6.2-liter V8
411 horsepower @ 5,500 rpm
434 lb-ft of torque @ 4,500 rpm
EPA city/highway fuel economy: 13/18 (2WD), 12/16 mpg (4WD), 11/16 mpg (Raptor)
With more than 30 different variants, the 2013 Ford F-150 pickup pricing covers a wide spread. Regular Cab XL models have a starting Manufacturer's Suggested Retail Price (MSRP) right around $24,600, while a fully-laden Limited SuperCrew can run well over $50,000. Somewhere in between those two extremes is where most buyers will find themselves. A look at the Fair Purchase Price on kbb.com shows the typical transaction price being paid for the 2013 Ford F-150 in your area, so be sure to check it out before you set out to buy. The F-150 is expected to retain a better-than-average residual value, with the SuperCrew models at the top of the chart, followed by the Regular Cab and then the SuperCab. Over a 5-year period, the F-150's projected residual value is expected to be nearly on par with the Chevrolet Silverado 1500 and GMC Sierra, better than the Ram 1500 and Nissan Titan, but slightly below the Toyota Tundra.
To compare current market prices, check out KBB.com's car classifieds to view the new and used Ford F150 Super Cab vehicles for sale near you.
Based on 565 Ratings for the 2009 - 2014 models.
Review this carBy Wild Bill on Sunday, March 09, 2014
I own this car - My approximate mileage is 20,000
overall rating 10 of 10rating detailsPros: "Lariate with lariate pacage and chrome package,"
Likely to recommend this car? (1-10): 10
"Great truck just be sure to upgrade the radio when you purchase, standard radio is weak. Drives great and gas milage isn't bad, city 15.1, hwy 21.5 with the V8 5.0. handles great in bad weather and love the 4 wheel drive automatic feature. Great vehicle and very happy with all features on it. Drives like a Lincoln on the hwy."
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By ross on Wednesday, March 05, 2014
I owned and sold this car
Reason: want something else
Pros: "great ride. great look. and comfortable"
Cons: "none, in my opinion"
Likely to recommend this car? (1-10): 10
"The truck still looks brand new. interior and exterior look great, no scratches, tires are good. has sprayed in bed liner, step on tail gate and tow package, and off road package, has power sliding back window."
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By Randy on Wednesday, March 05, 2014
I own this car - My approximate mileage is 30,000
overall rating 9 of 10rating detailsPros: "Roomy, solid, reliable, quiet, firm smooth ride"
Cons: "no tow hooks, MPG is lower than estimates"
Likely to recommend this car? (1-10): 9
"Sold my 2007 4 wheel 4 speed tranny F150 with 5.4 hoping for great fuel with the 4.6 and 6 speed tranny I now have. I only gained about 2 in the city and maybe 1 on the highway, Specs say I still have nearly same power and torque so a great advance. I like Chevrolet but the Ford is much more solid feeling and comfortable. I have owned several of both. Ford has always been the least repairs and tougher of the two. I will say Chevrolet gets closer on estimated MPG listings than Ford. I never get close to the estimates and drive decently. great truck. Huge comfort room inside. Wished tow hooks were still standard (I get in sand sometimes). I assumed they were standard until I noticed I had none. They used to be. Sync is very nice. I did not think would use it but I do a lot."
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By Nola_123 on Sunday, February 23, 2014
I own this car - My approximate mileage is 3,300
overall rating 9 of 10rating detailsPros: "Love the comfort, the height, the looks"
Cons: "Gas mileage is terrible. 11in city."
Likely to recommend this car? (1-10): 10
"Shopped several other trucks. Best truck for the money with all the bells and whistles. Labor Day incentives made this F-150 somewhat affordable. My last new vehicle before retiring. The F-150 Lariat has not disappointed me yet! Towing an 8k camper with no issues. All around great truck!"
1 person out of 1 found this review helpful
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By bearclaw on Sunday, February 23, 2014
I own this car - My approximate mileage is 17,000
overall rating 9 of 10rating detailsPros: "great truck , rides & drives like a Lincoln"
Cons: "could use a little more all terrain style tires"
Likely to recommend this car? (1-10): 10
"The 5.0 runs great with power to spare, 4x4 system with locking rear axle has gotten me out of more than a few Michigan snow in days. The stx package without floor carpet is great for the wet messy winter months , cleans up like new, no wet nasty carpet to deal with. Carpet belongs in a house not a truck... overall the f 150 sales the past 30 years says it all. They just get better every year. Hats of to FORD. Built without your tax dollar..."
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By Jack on Friday, February 21, 2014
I own this car - My approximate mileage is 9,000
overall rating 7 of 10rating detailsPros: "WONDERFUL COMFORT BUT POOR FUEL ECONOLY"
Cons: "NO HORSE POWER"
Likely to recommend this car? (1-10): 3
"I hoped to get at least 17 mpg, but i've been getting only about 14 on average. In addition, i don't have the power i'd like to, 6 cylinder engine DOES NOT TAKE OFF. I LIKE EVERYTHING ELSE ABOUT MY TRUCK"
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Signings & Events Calendar
2013 (1) Alitha Martinez (1) Amazing Spider-Man (1) Archie (3) Artist (1) atomic robo (1) Batman (2) Becky Cloonan (1) Betty (1) Book Club (8) Brad Bell (1) Brad Walker (1) Brandon T. Snider (1) brian clevinger (1) brian wood (2) Buying Day (1) chris claremont (1) Chris Eliopoulos (1) Comic Book History of Comics (1) Comic Con (1) comic store heroes (1) Con (1) convention (1) Convention New York (1) Cow Boy (1) Craig Yoe (1) Dan Slott (2) dark horse (2) Dark Horse Comics (2) Dark Knight Manual (1) Dark Knight Rises (1) David Mazzucchelli (1) DC Comics (1) Demo (1) detective comics (1) Doctor Strange (1) Dynamite (1) Edwin Huang (1) Event (1) Extinction Parade (1) Franco (2) frank miller (1) Fred Van Lente (1) Free Comic Book Day (1) Garth Ennis (1) George Takei (1) Green Team (1) greg pak (3) Guardians of the Galaxy (1) Guy Davis (1) Hal Johnson (1) hellboy (1) Husbands (1) Ian Flynn (1) IDW (2) Image (1) Image Comics (2) Immortal Lycanthropes (1) infinity gauntlet (1) Jane Espenson (1) Jennifer Blanc (1) jim krueger (1) Jim Lee (1) Jim Salicrup (1) Journet Into Mystery (1) Jupiter's Legacy (1) Kevin Keller (1) Kraven's Last Hunt (1) Madame Tussauds (1) Mark Millar (1) marvel (5) Matt Wagner (1) Max Brooks (1) Michael Biehn (1) Mick Foley (1) midtown comics (1) MRTIM (1) My Little Pony (1) Nate Cosby (1) nathan fox (1) national geographic channel (1) neal adams (1) NEW CRUSADERS RISE OF THE HEROES (1) new york comic con (6) nycc (5) Our Valued Customers (1) Red Circle Comics (1) Ryan Dunlavey (1) Sandman Mystery Theatre (1) Scott Snyder (2) scott wegener (1) Sean Murphy (1) Sell Your Comics (1) shane davis (1) Signing (6) Skullkickers (1) Spider-Man (2) Star Trek (1) Star Wars (1) Stephanie Buscema (1) Superman (2) thanos (1) The Boys (1) THE VICTIM (1) The Wake (1) tickets (1) Tim Chamberlain (1) Todd McFarlane (1) Trivia Contest (1) Valiant Comics (1) Veronica (1) Vertigo (2) Victor Gorelick (1) wolverine (1) World War Z (1) zach brunner (1) Zombie Survival Guide (1)
September – November 2012
Alitha and Ryan will be doing sketches for kids during the signing!
Purchase of NEW CRUSADERS: RISE OF THE HEROES #1 required for sketch, one per customer, time allowing.
Red Circle Comics presents "Ashes to Ashes," Part One! Our world demands heroes, and a new generation must rise! Over a decade ago, the super hero team known as The Mighty Crusaders did the impossible: they won. Successful in their battle against evil and finding they'd made the world a better place, the heroes settled down to the small town of Red Circle to start families, unwind and take a much-deserved rest. When the quiet town is rocked by the return of the ultimate evil, the super hero residents are obliterated! It's up to their heirs to fight for justice and crusade against evil. They are our last, best hope. They are The New Crusaders!
Join us as we welcome artist Stephanie Buscema and celebrate the release of IDW's all new comic My Little Pony Friendship Is Magic #1 at Midtown Comics Downtown on Wednesday November 28th from 6:30-7:30!
Stephanie will be there to sign her My Little Pony variant and talking with fans! Be sure to check out the Midtown Comics Exclusive cover for My Little Pony #1! We'll even be raffling off copies during the event!
My Little Pony Friendship Is Magic #1
Welcome to Ponyville, home of Twilight Sparkle, Rainbow Dash, Rarity, Fluttershy, Pinkie Pie, Applejack, and all your other favorite Ponies! Something's not right in the town though, as some of the inhabitants are acting very, very strange! It's up to the Mane Six to find the source of the weirdness before it's too late!


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The Public Eye sheds a critical light on irresponsible business practices and provides a platform to publicly criticize cases of human and labor rights violations, environmental destruction or corruption. The date and location of the Public Eye Awards are set deliberately to coincide with the annual meeting of the World Economic Forum. Those hiding behind closed doors in Davos allegedly to solve the world's problems often contribute to environmental destruction and human rights violations themselves. The Public Eye Awards remind the corporate world that the social and environmental consequences of their business practices affect not only people and the environment, but also the reputation of the company.
Today, the Public Eye consists of two "awards of shame", the People's Award and the Jury Award. They are awarded to corporations with a dismal record in terms of social and environmental responsibility.
Read more about the history of the Public Eye Awards
The Public Eye Awards aim to contribute to the overarching goal of social and ecological justice and demonstrate the necessity of effective and legally binding measures on a national and international level. Corporations need to be held accountable for their irresponsible business practices in their home state – no matter where these wrong-doings occur.


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February 2014
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Skip to main content
West Fargo Pioneer
Reading parade
School menu (March 12)
The Packer Weekly: Lexi Berg flourishes in the Big Apple
The Packer Weekly: Lexi Berg flourishes in the Big Apple
West Fargo honor rolls
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The Clinic open house set
Lebahn named top insurance salesman
High Point Networks adds two in West Fargo office
Sheeley promoted at Choice Financial
Exchange club honors Kelley
Insight from the West Fargo PD: IRS reveals 'Dirty Dozen' scams for 2014
Reuer: Hello, West Fargo
Insight from the West Fargo PD: Fireworks ordinance rewritten
Letter: Post prom/post grad committee needs parents
Letter: Teachers supported to teach 21st Century skills through event
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Lloyd Ohmdahl
Horace penny war helps local student
Library News (March 12)
'Fowl Play' comes to Bonanzaville
Local students receive degrees from NDSU
Senior Menu (March 12)
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nursery news
Freshman Mustangs take EDC title
Bowling scores (March 12)
Boys basketball season ends in EDC playoffs
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Packer girls take second in conference
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Flight Lines: Picking favorites not an easy task
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November 6, 2013
Deer hunting season starts Friday, respect property of others
A Recent news story highlighted a Norwegian hunter who accidentally shot a man sitting on the toilet after the hunter missed a nearby moose and the bullet pierced through a wooden cabin wall. The projectile whizzed straight past the animal, sliced through the building and hit the...
November 6, 2013 - 9:12am
October 22, 2013
West Fargo resident succeeds in Twist of Fate hunt
West Fargo resident Bob Syverson shot a doe over the last weekend in September with the help of Twist of Fate, an organization that sets up a three-day bow hunting trip for disabled hunters in the area. The 125-pound deer, shot with a crossbow, was Syverson's first deer claimed...
October 22, 2013 - 3:29pm
June 27, 2012
Open Season: Subtle start to dog training
My dog's breeder, Jeff Jalbert of Top Shelf Kennels in Horace, gave me a sideways glance as he set down his Busch Light on the polished wooden bar that wrapped along the south wing of Stiklestad Lodge near Fort Ransom, N.D.
June 27, 2012 - 12:00am
Local dog training club to host youth hunt, outdoors day
The Red River Valley Chapter of the North American Versatile Hunting Dog Association (NAVHDA) is offering a unique opportunity for area youths. The Fargo-based club's first annual Youth Hunt and Outdoors Day will be held Saturday, Aug. 11, approximately 30 miles west of Fargo at...
June 27, 2012 - 12:00am
June 13, 2012
True dog days of summer
On Saturday, it was 95 degrees as gusting winds blew heat like a hairdryer set on "inferno." By Sunday morning, people donned light jackets to brace against the 30-degree temperature swing, and scraped mud off their boots after late-night rains transformed the rolling prairie...
June 13, 2012 - 12:00am
May 16, 2012
Harwood's Staples wins Best of Show at Junior Duck Stamp Contest
The graceful canvasback duck, which inhabits the prairie wetlands of North Dakota, was the subject in a winning artwork that was named Best of Show in the North Dakota Junior Duck Stamp Contest, sponsored by the U.S. Fish and Wildlife Service. Mark Staples, 17, of Harwood, titled...
May 16, 2012 - 8:00am
March 28, 2012
Open Season: Back to the dog training grindstone thanks to spring
The transformation of my dog, Remy, from the beginning of last summer's training to the end of hunting season was nothing short of miraculous. By August, after months of training four to five times a week, the German wirehaired pointer was obedient both in the house and out in the...
March 28, 2012 - 12:00am
N.D. Game & Fish notebook: Report shows 2011 deer season success was lowest in recent history
As expected, North Dakota deer hunters took fewer deer last fall than in previous years, according to harvest statistics recently finalized by the State Game and Fish Department. Slightly more than 95,000 hunters took more than 49,000 deer during the 2011 deer gun season.
March 28, 2012 - 12:00am
February 29, 2012
Open Season: Snow geese sure signs of spring
Hunting waterfowl in the spring can be a tad unnerving. For one thing, it's weird being in a field that is about to be planted instead of harvested. Then there's the weather. Fall tends to be much more comfortable than spring, if for no other reason than it tends to be less...
February 29, 2012 - 12:00am
Local Delta Waterfowl chapter banquet set for March 9 in West Fargo
While duck hunting might seem like a long time from now, a local conservation group doesn't want outdoor enthusiasts to get too comfortable during the offseason. The Agassiz 4-Curls Delta Waterfowl chapter in Fargo is hosting its annual banquet March 9 at the Speedway Steakhouse...
February 29, 2012 - 12:00am
February 8, 2012
N.D. Game & Fish notebook: Midwinter waterfowl survey reveals record numbers
The North Dakota Game and Fish Department's annual midwinter waterfowl survey in early January revealed an estimated 279,000 birds, a record high for the number of ducks and geese wintering in the state. Mike Szymanski, migratory game bird biologist, said an estimated 90,000 Canada...
February 8, 2012 - 12:00am
January 11, 2012
A venison feast from the far east
Remy went downwind of where the crippled rooster had flopped into the tall stems of prairie grass and immediately turned and pointed.
January 11, 2012 - 12:00am
December 28, 2011
The good, the badlands, and the ugly dogs
Remy's tail wagged fervently as he worked the ground ahead. A strong breeze from the west pushed scent perfectly in his direction, and the 19-month-old pup used it to his advantage. "Good boy," I said. "Find the birds." Although young, Remy has picked up on the English language...
December 28, 2011 - 12:00am
December 14, 2011
Poor deer, pheasant numbers 'first taste of things to come'
The message from the North Dakota Game and Fish Department to hunters is clear: do not expect a quick turnaround from this year's low deer and pheasant numbers. In fact, for people who love the outdoors and hunting, the "good old days" may be right now, especially if current trends...
outdoors / news
December 14, 2011 - 12:00am
Open Season: A lot to be thankful for in North Dakota outdoors
The morning chill was every bit the 17 degrees promised by my digital truck thermometer, if not less. Almost immediately upon removing the Remington 870 pump shotgun from its case, lacy veins of frost enveloped the matte-finished barrel. There was no snow on the ground, but a slight...
December 14, 2011 - 12:00am
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Belotecan and Cisplatin in Treating Patients With Previously Untreated, Extensive-Stage Small Cell Lung Cancer
Recruitment status was Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Belotecan may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving belotecan together with cisplatin may kill more tumor cells.
PURPOSE: This phase II trial is studying how well belotecan works when given together with cisplatin in treating patients with previously untreated extensive stage small cell lung cancer.
Condition | Intervention | Phase |
Lung Cancer |
Drug: belotecan hydrochloride Drug: cisplatin |
Phase 2 |
Study Type: | Interventional |
Study Design: | Masking: Open Label Primary Purpose: Treatment |
Official Title: | Phase II Study of Camtobell Inj.(Belotecan) in Combination With Cisplatin in Patients With Previously Untreated, Extensive-Stage Small-Cell Lung Cancer |
- Response rate as assessed by RECIST criteria [ Designated as safety issue: No ]
- Overall survival [ Designated as safety issue: No ]
- Progression-free survival [ Designated as safety issue: No ]
- Hematologic and non-hematologic toxicity as assessed by NCI CTCAE v3.0 [ Designated as safety issue: Yes ]
Estimated Enrollment: | 46 |
Study Start Date: | October 2008 |
Estimated Primary Completion Date: | May 2010 (Final data collection date for primary outcome measure) |
- To assess the antitumor efficacy, in terms of objective response rate, of belotecan hydrochloride and cisplatin in patients with previously untreated extensive-stage small cell lung cancer.
- To assess additional evidence of antitumor activity as measured by overall and progression-free survival of these patients.
- To determine the safety and tolerability of this drug combination in these patients.
OUTLINE: Patients receive cisplatin IV on day 1 and belotecan hydrochloride IV on days 2-4.Treatment continues in the absence of disease progression or unacceptable toxicity.
Ages Eligible for Study: | 18 Years to 75 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Histologically confirmed small cell lung cancer meeting the following criteria:
- Extensive-stage disease
- Previously untreated disease
- At least one measurable disease
- No brain or leptomeningeal metastasis
- ECOG performance status 0-2
- Life expectancy ≥ 12 weeks
- ANC ≥ 1,500/mm^3
- Platelet count ≥ 100,000/mm^3
- Hemoglobin ≥ 9.0 g/dL
- Total bilirubin ≤ 1.5 mg/dL
- ALT and AST ≤ 2.0 times upper normal limit (ULN) (≤ 5.0 times ULN in the presence of liver metastasis)
- Alkaline phosphatase ≤ 2.0 times ULN
- Creatinine ≤ 1.5 mg/dL OR creatinine clearance ≥ 60 mL/min
- No active infection requiring intravenous antibiotics
- No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer or in situ cancer
- No other severe acute or chronic medical condition or laboratory abnormality that may increase the risk associated with study participation or investigational product administration, interfere with the interpretation of study results, or make the patient ineligible for study entry, in the judgment of the investigator
- No prior chemotherapy or radiotherapy
- No other concurrent chemotherapy, radiotherapy, or immunotherapy
Korea, Republic of | |
Yonsei Cancer Center at Yonsei University Medical Center | Recruiting |
Seoul, Korea, Republic of, 120-752 | |
Contact: Joo-Hang Kim, MD 82-2-2228-8131 email@example.com |
Principal Investigator: | Joo-Hang Kim, MD | Yonsei University |
Additional Information:
No publications provided
ClinicalTrials.gov Identifier: | NCT00754858 History of Changes |
Other Study ID Numbers: | CDR0000614308, YONSEI-4-2008-0127, CKDPC-YONSEI-4-2008-0127, YONSEI-07-YUHS-02 |
Study First Received: | September 17, 2008 |
Last Updated: | March 12, 2009 |
Health Authority: | Unspecified |
Keywords provided by National Cancer Institute (NCI):
extensive stage small cell lung cancer |
Additional relevant MeSH terms:
Lung Neoplasms Small Cell Lung Carcinoma Respiratory Tract Neoplasms Thoracic Neoplasms Neoplasms by Site Neoplasms Lung Diseases Respiratory Tract Diseases Carcinoma, Bronchogenic Bronchial Neoplasms Belotecan Cisplatin |
Camptothecin Antineoplastic Agents Therapeutic Uses Pharmacologic Actions Radiation-Sensitizing Agents Physiological Effects of Drugs Topoisomerase I Inhibitors Topoisomerase Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Antineoplastic Agents, Phytogenic |
ClinicalTrials.gov processed this record on March 10, 2014


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Womens | Color: Black | Style Number: 189901
Total Number of Reviews
100% say this shoe fits True to Width
Review By: Gail Pacific Grove CA 9/17/2012
Overall Rating:
half size small true to width
Really stylish. Cute little heel. Looked very good on my feet.Butsorry to say they were too short and a larger size isn''t available.
To add a review, please click here.
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In Stock. Ships out in 2-3 business days.
A lace-up ankle boot with flexible stretch goring.
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Watch stocks you care about
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When you think about the stocks you want to own so you can retire rich, your obvious thought is whichever one will rise the most. Yet if the last two years have taught us anything, it's that in addition to trying to maximize your returns, you also have to think about preserving capital and avoiding risk.
That's just one reason why the best stocks to help you both before and after retirement are those that pay healthy dividends. By demanding that companies pay you in order to invest in their shares, you screen out a lot of troublesome businesses and pick up some of the best stocks you can own.
How dividends get you ready to retire
One of the things those near retirement may want to start doing is to figure out where they're going to get the cash to pay for their expenses. While you're working, it's easy to leave your investments untouched, relying on your job income to take care of day-to-day bills.
But when your paycheck disappears, you want to be prepared. That's how dividend stocks can help. For instance, say you have $700,000 to allocate to stocks. If you've invested in growth stocks throughout most of your life, then the odds are good that you'll get little or no income from them -- leaving you in a position where you have to liquidate your holdings, even if they've fallen in value lately.
In contrast, if you invest that money into a portfolio of dividend-paying stocks, you can go a lot further toward replacing your job income after you retire. Take a look at this simple example:
Stock |
Current Yield |
Income on $100,000 |
6.3% |
$6,300 |
Heinz (NYSE: HNZ ) |
4.4% |
$4,400 |
Kimberly-Clark (NYSE: KMB ) |
4.1% |
$4,100 |
Kraft Foods (NYSE: KFT ) |
4.1% |
$4,100 |
Merck (NYSE: MRK ) |
5.1% |
$5,100 |
AstraZeneca (NYSE: AZN ) |
6.5% |
$6,500 |
Reynolds American (NYSE: RAI ) |
7.9% |
$7,900 |
Source: Yahoo! Finance.
All told, that comes to more than $38,000 in annual dividend income. Before you retire, you can use it to build up a cash cushion that you can draw from to pay your future bills. After you retire, it will cover part of your expenses, and may prove sufficient along with Social Security and other income sources to maintain your lifestyle without having to sell any of your long-term stock holdings.
Other great dividend perks
Some investors don't like dividend stocks because they have to pay taxes on the income they generate. Yet especially as you near retirement, you'll probably find that dividend stocks are among the best tax deals you have. Paying a maximum tax rate of 15% on qualified dividends on most widely held stocks is a pretty good deal -- and the current 0% rate on dividends for those in the lowest two tax brackets is the best gift the IRS has ever given to taxpayers.
In comparison, other funding sources carry much larger tax burdens. Tap a traditional IRA or 401(k), and you'll have to pay tax at your full ordinary rate, up to 35% -- and those tax rates could easily go up in the near future. And while you can withdraw from a Roth IRA without paying any tax, you'll forever lose the ability to earn additional tax-free income on that money.
Now, you might think that the benefits of receiving dividends might come only at the cost of giving up returns. Yet historically, dividend stocks have actually performed better than their non-dividend-paying counterparts.
Start getting paid today
So if you're approaching or in retirement, think about how dividend stocks can play a larger role in your investment strategy. With better returns, lower taxes, and the steady income that dividend-paying stocks provide, they definitely could help make your golden years much more comfortable.
For more about retiring rich:
- Do these three things or you'll end up penniless.
- Your surprise shortcut to financial ruin.
- Your retirement prospects may be worse than you think.
Start investing today -- just $7 per trade with Scottrade. Or find the broker that's right for you.


text:
Samsung goes bigger but lighter with Note 3, updates Note 10.1
Some of the most noticeable changes for the devices come in their design. The Note 3 sports a slightly larger screen than its predecessor, and both devices feature a svelte, new leather-effect rear casing edged with stitching. While still made of plastic, the new design gives the devices a more premium appearance. Samsung's products have faced criticism in the past for looking too "plasticy" when compared … Read more


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What does SMART mean in Laboratory?
This page is about the meanings of the acronym/abbreviation/shorthand SMART in the Medical field in general and in the Laboratory terminology in particular.
Senior Medication Assessment Research Trial
Find a translation for SMART in other languages:
Select another language:
What does SMART mean?
- smart(adj.)
- having or showing quick intelligence or ready mental capability:
Discuss this SMART abbreviation with the community:
Use the citation below to add this abbreviation to your bibliography:
"SMART." Abbreviations.com. STANDS4 LLC, 2014. Web. 16 Mar. 2014. <http://www.abbreviations.com/term/68376>.
SMART also stands for:
- Sales and Marketing Automated Relationship Technology
- Sales Marketing Administration Research Tracking
- Satellite Monitoring And Remote Tracking
- Satellite Multimedia Applications Research and Trials
- Save Money And Reduce Taxes
... and 108 more »
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Yesterday afternoon I went to log on, and somehow my password had been changed. After 5 login attempts I pushed the "I forgot the password" thingy and it gave me a new one and I had to wait 30 minutes.
Not a big deal, its all back to normal, just wondering, how did it happen?


text:
To do the cool things, you have to be logged in first.
The Portland Trail Blazers will open their 2013-14 home schedule against the defending Western Conference champion San Antonio Spurs on Saturday, Nov. 2 at the Rose Garden. Portland will tip-off its 44th NBA season on the road vs. Phoenix on Wednesday, Oct. 30, it was announced today by the NBA.Continue Reading
Written by trailblazers / avg. rating: 5
The Portland Trail Blazers and partner Verizon Wireless are offering an opportunity for a personal fan experience with Wesley Matthews on Sunday, March 3. Matthews will appear at the Clackamas Promenade Verizon Wireless store to meet fans, sign autographs and take photos. Continue Reading
Written by erikgundersen / avg. rating: 5
The Trail Blazers (26-31) were not able to make enough plays at the end of the game against the Denver Nuggets (37-22) and eventually lost 111-109. Damian Lillard led the way for the Trail Blazers with 26 points in a close loss. Continue Reading
The Portland Trail Blazers (26-30) look to build over their streak-snapping win on Sunday as they face the Denver Nuggets (36-22) in a Northwest division match-up. Denver and Portland have split the two games in the season series up to this point with the home team holding serve in both games. Tip-off at the Rose Garden is set for 7:30 and the game will be shown on CSNNW and televised nationally on ESPN. It can be heard on 1190 AM and 102.3 FM. Continue Reading
"We used to get it in on days off. Not too many guys went in but we would go in and really get after each other." Continue Reading
Written by Justin.Molter / avg. rating: 5
Guests include Head Coach Terry Stotts and new Trail Blazers Guard Eric Maynor Continue Reading
Tags: courtside
Wesley Matthews was on fire from deep all night long, hitting five threes and scoring 24 points to lead the Trail Blazers (26-30) to a 92-89 win over the Boston Celtics (29-27). The home victory helps the Trail Blazers snap a seven-game losing streak. Continue Reading
On Sunday evening the Trail Blazers (25-30) welcome the Boston Celtics (29-26) to the Rose Garden for their second and final meeting of the season. It will also be 70's night at the Rose Garden and tip-off is set for 6PM. The Trail Blazers will be looking to snap a 7-game loosing streak. Continue Reading
The Trail Blazers (25-30) were in a hard fought battle with the Lakers (27-29) from the opening tip off. A couple of close plays in the final minutes didn't go Portland's way and they lost in 111-107 thriller. JJ Hickson (11 rebounds) and Nicolas Batum (eight rebounds) led the Trail Blazers with 22 points apiece. Continue Reading
On Friday, the Trail Blazers (25-29) face the Los Angeles Lakers (26-29) for their third meeting of the year. Tip-off is set for 7:30 at Staples Center and will be shown on CSNNW and can be heard on 1190 AM and 102.3 FM. Continue Reading
Written by trailblazers / avg. rating: 4
The Portland Trail Blazers have acquired guard Eric Maynor from the Oklahoma City Thunder in exchange for the draft rights to Georgios Printezis, it was announced today by General Manager Neil Olshey. Continue Reading
The Rose Garden has been named the sixth most vegetarian-friendly basketball arena by People for the Ethical Treatment of Animals (PETA). The Rose Garden is operated by Ovations Food Services, a nationally ranked specialist in food and beverage catering and concessions for public assembly facilities. The arena features more than 35 unique concession stands and kiosks, in addition to two full service restaurants. Continue Reading
Written by erikgundersen / avg. rating: 4
The Trail Blazers (25-29) fell victim to a poor defensive start to the game and could never quite recover as they eventually lost 102-98. The Phoenix Suns (18-36) were able to hold off a late Portland run in the final minutes to win the game. JJ Hickson scored 25 points and grabbed 16 rebounds in the loss, his third 25-point, 15-rebound game of the year. Hickson is one of four players in the NBA with two games of 25-plus points and 15-plus rebounds along Tim Duncan, Dwight Howard and Zach Randolph. Continue Reading
After a weekend spent marveling at the stars of the NBA, the season returns on Tuesday. With the NBA regular season underway again, Portland is one of the cities where dreams of playing beyond the thirty games left on the schedule is still working itself out. The Trail Blazers (25-28) begin their push for the playoffs once again on Tuesday against the Phoenix Suns (17-36) at the Rose Garden. Tip-off will be at 7PM and will be shown on CSNNW and can be heard on 1190 AM and 102.3 FM. The Trail Blazers will be looking to snap a five-game losing streak. Continue Reading
"The NBA, and indeed all of sports ownership, has lost a titan and innovator in Dr. Jerry Buss. At a time when professional basketball needed an infusion of new thinking and vision, Dr. Buss stepped forward in ways that truly redefined our game on and off the court. He will be missed as a father, owner, leader and friend. Our thoughts and prayers go out to the Buss family and the entire Los Angeles Lakers organization." Continue Reading
LaMarcus Aldridge grabbed four rebounds, blocked two shots and dished one assist in 11:27 helping the Western Conference win the 2013 All-Star game 143-138. Chris Paul was named the game's MVP with 20 points and 15 assists. Continue Reading


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343 SERRANO AVE SANTA ROSA, NM 88435 Listing Price $ 41,873 Sold 11/14/2012 Listing Information Details Save
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The snow was gone bare sidewalks and now a winter wonder land. A female cardinal and a junco pecking on the seed that has fallen to the ground. The female cardinals are a beautiful olive color. Both birds give a beautiful contrast on the snow.
Snow keeps coming.
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Technique - Knit
A simple, rolled-edge vest with a twist.This stylish yet simple unisex vest can be worn open with a crossed collar or as a shawl! Knit with 1,000 (1,100, 1,300, 1,300, 1,600, 1,600) yds of DK-weight yarn at a gauge of 20 sts and 26 rows per 4" using U.S. size 6/4mm circular needle.Finished measurements:
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Publications: Beckwith, Jo-Anne
Journal Article
Beckwith, J.A. and Clement, S. (2013) Barriers to voluntary improvement of residential fertiliser practices in the Peel-Harvey Catchment. Australian Journal of Water Resources, 17 (1). pp. 65-76.
Beckwith, J.A. and Moore, S.A. (2001) The influence of recent changes in public sector management on biodiversity conservation. Pacific Conservation Biology, 7 (1). pp. 45-54.
Conference Item
Genter, S., Beckwith, J.A., Howard, K. and Hardy, G. (2010) Evaluation of a Phytophthora dieback management framework. In: 5th IUFRO Phytophthora Diseases in Forests and Natural Ecosystems, 7 - 12 March, Auckland and Rotorua, New Zealand.
Beckwith, J.A., Moore, S.A., Clement, S.E., Curnow, B.D. and Admiraal, R. (2010) The impact of forest thinning on perceptions of recreational value and forest health: technical report of research findings: Wungong catchment trial. Beckwith Environmental Planning and Murdoch University, Perth.


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Home » Rothera Diaries » Rothera Diaries 2003 » May - Winter Arrives » May - Centurian Night »
Birthdays are a good excuse for a party. The official line, of course, is that we are boosting base moral. So, when it was Adam's birthday, the youngest member on base, it was decided that a Centurion Evening was just the ticket.Ā Preparation was intense hours spent in the chippie shop, garage or rooting around for something suitable.Ā The best efforts included Jane (the Doc) donned in silver, wings flying from a hard hat, as Mercury, Chris (the Mech) making a sterling effort not only wearing body armour but also making a splendid entry, riding on board of his chariot!Ā Weapons were abundant including beautifully crafted wooden (very safe) swords (Baz the Genny Mech), a couple of broad swords, axes, a claymore, etc., etc. of course, all of these were suitable for OH&S.Ā
Once all were gathered we feasted upon a meal sumptuously produced by our ever-wondrous chef (Issy) and then the games commenced.Ā The pole game proved the most popular. The aim is to knock your opponent off a suspended pole, with a pillow, while trying to maintain your own balance.Ā There were some excellent battles and some excellent battlers! The expressions on faces told many a story that will no doubt be told again in the months to come.
Kirsty Brown Marine Biologist
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More Drugs? How About Less Bacon?
The fact is, roughly 90% of people taking cholesterol-lowering drugs do not really need them. Their cholesterol problem is caused by the cholesterol and animal fat in the foods they eat. If they were to eliminate animal products and other fatty foods from their diets, the problem would vanish for the vast majority.


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Mathom, the God of Delays, is an overlooked but powerful entity. Few worship him, but many remember him with word and deed.
A transcription, beyng the seminal introduction by Mr S J Ponsuler to the theory and praxis of Dracapodemy, the studie of Dragons' migration patterns. This tome ys to be founde in the librarie of Anserne University, alonge with many years of copies of the Dracapodemyst's Almanac not to mention verious othere tomes on the subjecte.
(Another submission I'm transferring over to the main site from the fora).
Magic is a living entity, simple and non-sentient, but reactive to large-scale emotional states. Its name, like we might call a dog, "Dog", is Garan. It is better to think of it as a huge astreal vine like plant, rather than an animal.
After Buddha died, his shadow was still shown for centuries in a cave—a tremendous, gruesome shadow. God is dead; but given the way of man, there may still be caves for thousands of years in which his shadow will be shown. And we—we still have to vanquish his shadow, too.
-Frederick Nietzsche
Thaumatechnology - in a world where straight magic has an unnerving tendency to get the user killed, either by magical catastrophe or by being lynched by an upset mob, this is a much safer form of magical use… Even if it does occasionally explode.
Recently unearthed this gem of mine, and thought to post it. Its writing predates my joining of Strolen, and I found quite a few interesting bits in it. It is nearly completely written and I am going to endeavor to finish writing it out. Until then, I plan to post it here, perhaps a section a day or so. Enjoy, expand, criticism, comment.
Humans are very emotional beings, and feel things much more strongly than most other creatures. Sometimes, they feel things a little too strongly.
"Anyone can draw a map, boy - there's no more difficulty in that than laying brick. What makes maps useful is when they are so proper, so precise, that they are living images of the places they represent. Encompassing knowledge of the geography, and mastery of the very space itself - that, child, is cartogramancy."
- Sage Pakpao Sasithorn, Chief Lecturer, the Ezagun-Darkbolt College of Cartogramancy
In the early days of Hewdamia, the Gods squabbled over the world and took what they could from the each other. There was little here but water and soil, yet the Three Gods fought over it still. The arrival of the newer Gods marked a turning point in the world as well as the Gods. The arrival marked the beginning of a war that wouldn't see the first blow for centuries.
A composite calendar devised by magi based on the movement of the stars rather than the movement of the moon or the sun.
I have never been happy with the way that magical constructs were presented in games. Admittedly, a large statue stomping the surrounding countryside is an impressive image. But the logic (or lack thereof) involved has always bothered me.
For want of a nail a horse was lost
For want of a horse a rider was lost
For want of a rider a message was lost
For want of a message a battle was lost
For want of a battle a kingdom was lost…
Which serves as a warning not to get on the wrong side of the God of Smalll Things.
Demons are the darker emotions, the destructive forces of creation. In primeval times the demons awoke alongside the gods and the angels, and were herded by the greater powers, chased into hell, even as the angels were led into heaven.
The young priest had been healing in the market place for free. Someone seeking bounty gold had told someone at the temple. "Hut. Hut. Hut" The Temple Knights in formation came marching down from the temple.
The young priest stood up. He reached into his pouch. With a smile he put the top into the Bey. With a spin, the 1000 prayers to the spirits came forth. The spirit responded. The wind whirled and buffetted the troops. They fell into each other and were having trouble getting due to the wind that only they felt.
The priest picked up his top and ran away. They would not catch him today.
The magic in my roleplay system is based around gemstones. It started off with the fact that wizards could use gems to regain lost mana: essentially, the gems were nothing more than glorified potions of mana. Since then I've managed to expand the uses of gems considerably and make them much more integral to the magic system; however, I still feel there is a lot more that I could do with them if I could only think of it! Basically, I'm asking for any ideas and suggestions that people have on how to make the gems and magic more interlinked.
The mind of a wizard is more open to the more esoteric elements of his surroundings ââ?¬â?? this is why he is able to perceive the weave of the Great Tapestry that is the multiverse, and pull at the strings. This increased sensitivity can manifest in several ways.
It is the Year of Furtive Shadows, and everyone can smell the changes in the wind. Everyone, from the lowest scully boy up to the regents, knew, deep down, that something must happen soon.
There is a person who has a well-known reputation, probably involving something illegal. But this person is either very clever and crafty, or really like his or her privacy, for no one knows who this person actually is. As an added twist, perhaps this person is of an age that would noramlly be wildly inappropriate (say, a child is a much-feared bandit) or maybe not the expected gender or even race.


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Additional Group Tour Information: Reservations recommended.


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GLUE DOTS-XXL Glue Dots. These thick; double-sided adhesive dots are great for cards; scrapbook pages; paper crafts; and more. Glue Dots always keep their shape and bond to most surfaces including paper; plastic; metal; wood; foam; and more. This package contains twenty-four 2x2x1/8 inch clear adhesive dots in a re-sealable package. Acid free. Made in USA.


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How brain science will change computing
Share this talk and
track your influence!
Treo creator Jeff Hawkins urges us to take a new look at the brain — to see it not as a fast processor, but as a memory system that stores and plays back experiences to help us predict, intelligently, what will happen next.
This talk was presented at an official TED Conference. TED's editors featured it among our daily selections on the home page.
- Interactive transcript (28 languages)
Enthusiastically agree? Respectfully beg to differ? Have your say here.
There are currently no comments for this talk.


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Companies like Dominion often hire independent contractors to do some of their construction projects.
Steve White, executive director of the ACT Foundation, has been particularly critical of those contractors for bringing in almost all their workers from other states.
Plans to expand Marcellus Shale gas production have also stirred up local opposition from residents concerned about the environmental impact that deep drilling for the gas will have on the stability of their lands and purity of their streams and underground waters.
Marcellus and Utica Shale deposits run from southwestern New York through Pennsylvania down to eastern Ohio and West Virginia and are among the world's largest natural gas deposits.
Last year, three West Virginia cities -- Lewisburg, Morgantown and Wellsburg -- banned Marcellus Shale drilling within their borders.
Last month, two New York state judges in Otsego and Tompkins counties ruled that local governments have the power to ban fracking for gas, challenging a New York state regulation that local governments cannot do that.
More than 50 local communities in New York have passed bans on gas drilling within their borders.
The "Marcellus Principles" are online at: www.jobsforlocalworkers.com.
Reach Paul J. Nyden at pjny...@wvgazette.com or 304-348-5164.


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Please enter your travel dates.
Two double beds
- FREE Wifi
Wifi is included in your stay.
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Self parking is included in your stay.
Two Double Beds, Non-Smoking, Accessible
- FREE Wifi
Wifi is included in your stay.
- FREE Parking
Self parking is included in your stay.
One king bed
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Wifi is included in your stay.
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Room, Accessible, Non Smoking
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Wifi is included in your stay.
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Self parking is included in your stay.
Kimberly hotel with an indoor pool
Situated in the city center, this hotel is close to Telulah Park, Gardens of the Fox Cities, and Reid Municipal Golf Course. Local attractions also include Lawrence University and Appleton Memorial Park.
Hotel Features
In addition to a restaurant, Hilton Garden Inn Appleton/Kimberly features an indoor pool. Other amenities include a bar/lounge and a coffee shop/café.
Room Amenities
Guestrooms have complimentary wireless Internet access, microwaves, and air conditioning; rooms also include climate control and safes.
Information missing or incorrect? Tell us!Hotel Amenities
- General
In addition to an indoor pool, Hilton Garden Inn Appleton/Kimberly provides a spa tub and a 24-hour fitness center. Dining options at the hotel include a restaurant and a coffee shop/café. A bar/lounge is on site where guests can unwind with a drink. High-speed wireless Internet access is complimentary.
A 24-hour business center is on site at this 3-star property. Event facilities measuring 2090 square feet (188 square meters) include conference/meeting rooms. This business-friendly hotel also offers gift shops/newsstands, laundry facilities, and dry cleaning/laundry services. A roundtrip airport shuttle is complimentary to guests during limited hours. Complimentary self parking is available on site.
Hilton Garden Inn Appleton/Kimberly is a smoke-free property.
- Free Wi-Fi
- Meeting facilities size (feet) - 2090
- Meeting facilities size (meters) - 188
- Number of meeting/conference rooms - 3
- Free self parking
- 24-hour fitness facilities
- 24-hour business center
- Number of buildings/towers - 1
- Multiple large conference rooms
- Airport transportation (complimentary)
- Total number of rooms - 125
- Air-conditioned public areas
- Restaurant
- Room service (limited hours)
- Number of floors - 5
- Business services
- Coffee shop or café
- Express check-out
- Dry cleaning/laundry service
- 24-hour front desk
- Laundry facilities
- Luggage storage
- Gift shops or newsstand
- Shopping on site
- Bar/lounge
- Elevator/lift
- Express check-in
- Safe-deposit box at front desk
- Smoke-free property
- Spa tub
- Swimming pool - indoor
- Internet
Available in all rooms: Free Wi-Fi
Available in some public areas: Free Wi-Fi
- Parking
Free self parking
- Room Amenities
- Cribs/infant beds (complimentary)
- Free Wi-Fi
- Minibar
- Microwave
- Hair dryer
- Bathtub only
- Iron/ironing board
- Rollaway/extra beds available
- Air conditioning
- Complimentary newspaper
- In-room safe
- Climate control
- Dining
Great American Grill - This restaurant specializes in American cuisine and serves breakfast and dinner.
Room service (during limited hours) is available.
- Recreation
An indoor pool and a spa tub are on site. Other recreational amenities include a 24-hour fitness center.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
Policies & Fees
- Check-in
Check-in time starts at 3 PM
- Check-out
Check-out time is 11 AM
- Payment types
Accepted at this hotel: American Express, Carte Blanche, Diners Club, Discover, MasterCard, Visa, JCB International
- Pets
Pets not allowed
- General
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- Fees
- The following fees and deposits are charged by the property at time of service, check-in, or check-out.
- Breakfast fee: USD 9.95 per person (approximately)
- Rollaway bed fee: USD 10 per night
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.


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450 with white engineModerator: Team Cub
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450 with white engineQuestion I have a 450 I-H tractor with a white engine block was there ever a demo in that series?
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Trnp1 Regulates Expansion and Folding of the Mammalian Cerebral Cortex by Control of Radial Glial Fate
Trnp1 Regulates Expansion and Folding of the Mammalian Cerebral Cortex by Control of Radial Glial Fate
Cell, Volume 153, Issue 3,
Pages 535-549,
Publication Date 25 April 2013
Copyright © 2013 Elsevier Inc. All rights reserved.
DOI: 10.1016/j.cell.2013.03.027
Ronny Stahl
Tessa Walcher
Camino De Juan Romero
Gregor Alexander Pilz
Silvia Cappello
Martin Irmler
José Miguel Sanz-Aquela
Johannes Beckers
Robert Blum
Víctor Borrell
Magdalena Götz
Physiological Genomics, Institute of Physiology, Ludwig-Maximilian University Munich, Schillerstrasse 46, 80336 Munich, Germany
Munich Center for Integrated Protein Science CIPSM, Butenandtstrasse 5-13, 81377 Munich, Germany
Institute of Stem Cell Research, German Research Center for Environmental Health, Helmholtz Center Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany
Institute of Experimental Genetics, Helmholtz Center Munich, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany
Instituto de Neurociencias, Consejo Superior de Investigaciones Cientificas-Universidad Miguel Hernandez, 03550 Sant Joan d'Alacant, Spain
Service of Pathology, Hospital Universitario "Principe de Asturias," 28805 Alcalá de Henares, Spain
Technical University Munich, Chair of Experimental Genetics, 85350 Freising-Weihenstephan, Germany
Munich Cluster for Systems Neurology (SyNergy), 80336 Munich, Germany
Corresponding author
Present address: Institute for Clinical Neurobiology, University of Würzburg, 97078 Würzburg, Germany
Evolution of the mammalian brain encompassed a remarkable increase in size of the cerebral cortex, which includes tangential and radial expansion. However, the mechanisms underlying these key features are still largely unknown. Here, we identified the DNA-associated protein Trnp1 as a regulator of cerebral cortex expansion in both of these dimensions. Gain- and loss-of-function experiments in the mouse cerebral cortex in vivo demonstrate that high Trnp1 levels promote neural stem cell self-renewal and tangential expansion. In contrast, lower levels promote radial expansion, with a potent increase of the number of intermediate progenitors and basal radial glial cells leading to folding of the otherwise smooth murine cerebral cortex. Remarkably, TRNP1 expression levels exhibit regional differences in the cerebral cortex of human fetuses, anticipating radial or tangential expansion. Thus, the dynamic regulation of Trnp1 is critical to control tangential and radial expansion of the cerebral cortex in mammals.


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