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Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis (DUET)
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This study will investigate whether RE-021 (Sparsentan), a selective dual-acting receptor antagonist with affinity for endothelin (A type) and angiotensin II receptors (Type 1), is safe and effective in treating patients with focal segmental glomerulosclerosis (FSGS).
Condition | Intervention | Phase |
Focal Segmental Glomerulosclerosis |
Drug: RE-021 (Sparsentan) Drug: Irbesartan |
Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Investigator) Primary Purpose: Treatment |
Official Title: | Efficacy and Safety of RE-021, a Dual Endothelin Receptor and Angiotensin Receptor Blocker, in Patients With Focal Segmental Glomerulosclerosis (FSGS): a Randomized, Double-Blind, Active-Control, Dose-Escalation Study |
- Evaluate change in urine protein/creatinine (Up/C). [ Time Frame: 8 weeks ] [ Designated as safety issue: Yes ]Primary efficacy objective is to determine the change in Up/C in FSGS patients receiving RE-021 (Sparsentan) over a range of dose levels compared to treatment with irbesartan as active control.
- Characterize serum PK of RE-021 (Sparsentan) over the range of doses administered to FSGS patients [ Time Frame: 8 weeks ] [ Designated as safety issue: Yes ]Evaluate the exposure or dose versus response relationship of primary and secondary PD/Biomarker endpoints.
Estimated Enrollment: | 100 |
Study Start Date: | December 2013 |
Estimated Study Completion Date: | December 2015 |
Estimated Primary Completion Date: | December 2014 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: RE-021 (Sparsentan) 200 mg
RE-021 (Sparsentan) will be administered as a single oral morning dose. In this ARM the RE-021 (Sparsentan) dose will be 200mg. Patients at >/= 50kg will receive half the RE-021 (Sparsentan) dose for the 8 week duration. |
Drug: RE-021 (Sparsentan)
Oral, once-daily
Other Name: Sparsentan
Experimental: RE-021 (Sparsentan) 400 mg
RE-021 (Sparsentan) will be administered as a single oral morning dose. In this ARM the RE-021 (Sparsentan) dose will be 400mg. Patients at >/= 50kg will receive half the RE-021 (Sparsentan) dose for the 8 week duration. |
Drug: RE-021 (Sparsentan)
Oral, once-daily
Other Name: Sparsentan
Experimental: RE-021 (Sparsentan) 800 mg
RE-021 (Sparsentan) will be administered as a single oral morning dose. In this ARM the RE-021 (Sparsentan) dose will be 800mg. Patients at >/= 50kg will receive half of the RE-021 (Sparsentan) dose for the 8 week duration. |
Drug: RE-021 (Sparsentan)
Oral, once-daily
Other Name: Sparsentan
Active Comparator: Irbesartan 300 mg
The control will be administered irbesartan as a single oral dose of 150mg for the first week before escalating to 300mg for the remaining 7 weeks. Patients at >/= 50kg will receive 150mg irbesartan for the 8 week duration. |
Drug: Irbesartan
Oral, once-daily
Other Name: Avapro
Detailed Description:
Focal segmental glomerulosclerosis (FSGS) is a rare glomerular disorder which results in frank proteinuria and progression to end-stage kidney disease (ESKD) over 5-10 years. Proteinuria reduction is widely regarded to be beneficial, and is considered the primary goal of treatment in FSGS and slowing its progressive course (D'Agati, et. al, 2011). Patients are currently treated with steroids, calcineurin inhibitors, angiotensin receptor blockers (ARB) and angiotensin converting inhibitors (ACE) to lower proteinuria (Cameron, 2003). Despite these therapies, many patients have nephrotic range proteinuria and new therapeutic agents are needed (Kiffel, et. al, 2011). Endothelin receptor antagonists (ERA) have been shown to lower proteinuria in clinical trials of diabetic nephropathy (Kohan, et. al, 2011) (Mann, et. al 2010) and have been speculated to be effective in FSGS (Barton, 2010).
Ages Eligible for Study: | 8 Years to 65 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Biopsy-proven primary FSGS (Primary FSGS confirmed by renal biopsy report) OR documentation of a genetic mutation in a podocyte protein associated with the disease.
RATIONALE: This study will include patients with primary FSGS. In most cases, the diagnosis will be based on histopathological findings in a kidney biopsy. Detection of a podocyte mutation that is causative of FSGS will be limited to patients who have proteinuria above the threshold to qualify for the trial and who have a first order relative with biopsy-confirmed FSGS. Under these circumstances, genetic testing may be performed in lieu of a biopsy. If these patients have an abnormal genetic test result, they will be considered to have primary FSGS and will be eligible for inclusion in the study;
- Males or females 8 to 65 years of age with informed consent signed by patient or guardian;
- Mean seated BP >100/60 and <140/90 in adults. Mean seated BP for children should be <95th percentile for age, gender, and height;
- Urine protein/creatinine ratio at or above 1.0 g/g; and,
- eGFR >30.
Exclusion Criteria
- Patients who are on immunosuppressive medications at the time of screening are eligible for the study. However, the doses of the medications must be stable for at least 1 month prior to randomization and cannot be changed during the 8 Week Treatment Period. Patients on Rituximab will be eligible provided they have a normal CD20 count;
- Use of pioglitazone within 30 days of randomization;
- Patients with a requirement for any of the medications indicated on the list of Excluded Medications (see Appendix A);
- Patients who have had a kidney transplant;
- Women who are pregnant and/or breastfeeding;
- Hospitalization for surgical procedures or anything requiring NPO status within 4 weeks of randomization and dosing;
- HCT <27 or Hgb <9;
- History of malignancy other than adequately treated basal cell or squamous cell skin cancer;
- NT-proBNP ≥200 pg/mL (57.8 pmol/L) in adults;
- Patients with a history of myocardial infarction or NYHA Class II-IV heart failure;
- Patients with clinically significant cardiac conduction defects, including second or third degree AV block, left bundle branch block, sick sinus syndrome, atrial fibrillation, atrial flutter, an accessory bypass tract, or any arrhythmia requiring medication;
- Patients with hemodynamically significant valvular disease;
- Patients with a history of cerebrovascular accident or transient ischemic attack;
- Patients with BMI >40
- Patients with FSGS secondary to another condition;
- Patients known to be HIV, HBV, or HCV positive;
- Patients with jaundice, hepatitis, or known hepatobiliary disease (includes asymptomatic cholelithiasis); ALT and/or AST >2 X ULN at Screening;
- Patients who have clinical laboratory values at Screening, which are designated by the investigator as clinically significant;
- Patients with history of type 1 or type 2 diabetes mellitus, or fasting blood glucose >125 mg/dL at screening (after repeating the test);
- Patients with a history of drug or alcohol abuse within the past two years;
- Patients with a history of an allergic response to any angiotensin II antagonist or endothelin receptor antagonist;
- Women of child bearing potential who are unwilling or unable to use an acceptable method of contraception to avoid pregnancy for the entire study period including from one month prior to randomization and for a period of at least 30 days after the last dose;
- Patients who have participated in another investigational drug study within 28 days prior to signing the informed consent form, or who will participate in another drug study during the course of this study;
- Prior exposure to RE-021, DARA or PS433540; or
- Patients who are involved in the study as research site personnel.
Contact: Horacio Plotkin, M.D. | 1-617-500-7982 | firstname.lastname@example.com | |
Contact: Howard Trachtman, M.D. | 646-501-2663 | email@example.com |
United States, New York | |
NYU Langone Medical Center | Recruiting |
New York, New York, United States, 10016 | |
Contact: Howard Trachtman, M.D. 646-501-2663 firstname.lastname@example.com | |
Contact: Suzanne Vento, RN 646-501-2663 email@example.com | |
Principal Investigator: Howard Trachtman, M.D. |
Principal Investigator: | Howard Trachtman, M.D. | NYU School of Medicine |
No publications provided
Responsible Party: | Retrophin, Inc. |
ClinicalTrials.gov Identifier: | NCT01613118 History of Changes |
Other Study ID Numbers: | RET-D-001 |
Study First Received: | June 4, 2012 |
Last Updated: | January 3, 2014 |
Health Authority: | United States: Food and Drug Administration |
Keywords provided by Retrophin, Inc.:
Primary FSGS Nephrotic syndrome Steroid Resistant |
Additional relevant MeSH terms:
Glomerulosclerosis, Focal Segmental Glomerulonephritis Nephritis Kidney Diseases Urologic Diseases Irbesartan Angiotensin Receptor Antagonists |
Antihypertensive Agents Cardiovascular Agents Therapeutic Uses Pharmacologic Actions Angiotensin II Type 1 Receptor Blockers Molecular Mechanisms of Pharmacological Action |
ClinicalTrials.gov processed this record on March 13, 2014


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180 Sandy Cove Rd Terence Bay, NS South Shore
t: 902-852-1557e: ns.sympatico.ca
Open between May 15 - Oct 15
Interpretation centre and park with monument commemorating the worst single-vessel marine disaster to occur off the Canadian coast prior to the sinking of the Titanic; remains of 277 victims are interred in the park. Walking trail and seaside boardwalk with memorial benches and gazebo.
park open year-round (no winter maintenance).
Details: Admission free; donations appreciated.

subset: commoncrawl


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, ,
Loop scarf in black from VPL. This mohair-merino scarf features a wide orange panel, a thin brown panel, and a loose knit throughout. Measures 35" long and 10" wide. Item ID:10284901
Composition: Polyamide 30%, Composition: Mohair 67%, Composition: Merino 3% WASHING INSTRUCTIONS : Dry Clean OnlyBrand Style ID : 74963LOOPSCARF
Need help? Click here to contact our Customer Services team.


text:
RedHead® Short-Sleeve Camo T-Shirts for Youth
Sale price: Clearance price: Starting at: Sale starting at: Clearance starting at: Reg. price:
- Tapered shoulder seams
- Full cut
- 100% cotton
Outdoor Answers
Get help about this item from fellow customers.
Ask your questions. Share your answers.
This is an old question, but maybe someone else can use this info? :)


text:
Jane Wyatt Age: 96actress of stage and screen who played the archetypical suburban mother on the 1950s TV show Father Knows Best. Her many other roles included the female lead in Frank Capra's Lost Horizon, and even Spock's mother on Star Trek. Died: Bel Air, Calif., October 20, 2006Information Please® Database, © 2007 Pearson Education, Inc. All rights reserved.
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"If they can go to work and have a good job," Krafczyk said, "that certainly is a big plus in your life."
At the opposite end of the spectrum is McDowell County.
McDowell County Commission President Gordon Lambert said much of the county's health problem is related to drug abuse.
"We're probably number one in the state, and the state was number one [nationwide] from deaths by overdosing," Lambert said.
West Virginia tied with New Mexico for the most prescription-drug overdoses in 2008, according to a November 2012 policy brief from the U.S. Centers for Disease Control and Prevention.
Lambert said the county needs more Suboxone clinics to treat drug-addicted residents, but officials are having trouble getting the funding to pay for them.
"We asked for help with Suboxone clinics and ended up with one that can see 12 people," Lambert said. "We probably need one to see 500 people."
As a result, McDowell residents travel "all over" for treatment, he said.
Lambert pointed to community agencies such as McDowell County's F.A.C.E.S. (Families, Agencies, Children Enhancing Services) that aims to, among other things, combat the county's high drug abuse rates.
The county also has a fitness center where residents can exercise at no cost, he said.
For the complete county list, go to www.countyhealthrankings.org.
Reach Lori Kersey at lori.ker...@wvgazette.com or 304-348-1240.


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The awesome hd wallpapers and backgrounds application for android.New Backgrounds added daily.
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Outfeet by designer Aviya Serfaty endeavors to change that perception by transforming the traditional artificial limb into an appealing fashion accessory which also becomes an extension of the natural movement.
#7076This latest favorite among the T by Alexander Wang bras has the best, most innovative shape of them all. Flattering on all sizes, it can be worn casually or dressed-up.
#7071Sylvain Sylvian prides itself in its choice of fabrics and sharp silhouette constructions. The range is created to be more sophisticated and refined that include suits and more tailored garments.
#7070Laura Kranitz creates these unique headbands by connecting feathers on a gold chain and a silk headband.
#7068Nixon Gunship collection has a uniquely applied finish designed to wear increasingly with age, resulting in a piece whose scars reveal a hidden character all its own.
#7067Totally obsessed with these flat black boots from Botkier! They are versatile and classic but definitely not plain. The strap details and exposed zippers give them that little extra something to make them ultra-cool and modern.
#7064My favorite piece of the Julie Park Fall Collection, the asymmetrical stripe cashmere sweater. Fitted on the hips, the top portion is meant to be draped loosely over, creating an interesting bias effect.
#7063First bag I've seen in awhile that I really want.. The "Brice" by Jerome Dreyfuss. Love the green!
#7060Polly Mellen in a Lisa Marie Fernandez Suit photographed by Steven Meisel-- Iconic on so many levels.
#7059Might seem like Lanvin overload around here lately, but these are just unbelievable. Looove these
#7056How beautiful is this Steven Alan hooded cape? It's perfect for pumpkin picking, leaf crunching, and cider sipping this Fall.
#7054Kimberly Ovitz' "Stuart Vest" should be named something much more rock n roll like the Black Widow. Webs/rib cages of faux suede with lengthy fringe.
#7045Mary Meyer's combination of whimsical prints with classic cuts gives her clothing a spunky edge. This plain black dress with a printed attached circle scarf is mind-blowing!
#7043EVERY TIME we think Golden Goose couldn't possibly make another pair that's as cool or better than the one we love now, they make a better pair!
#7039KZO's 3/4 sleeve plaid shirt - an interesting take on the traditional men's button-up.
#7035Seattle based Actual Pain release a little series of exquisitely hand crafted silver rings inspired by the blood drinking days of old…


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Pros and Cons of Spanking your Child
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One of the most controversial issues parents face when raising their children is whether to use spanking as a form of punishment. In this episode of The Lab, Daddy Clay and Daddy Brad talk with Dr. Elizabeth Gershoff, a professor who has been researching the topic. She explains the differences between corporal punishment and spanking. She also tells us why moms and dads spank their kids, along with whether or not spanking is on the decline.


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Past Keynote Speakers and Award Winners
Julian Bond, Former National Director of the NAACP; keynote
Andrew Young, Former U.S. Ambassador to the United Nations, U.S. Congressman, and Mayor of Atlanta, GA; keynote
Gwen Anderson, Director of the Utah Valley University Multicultural Center, received the Martin Luther King, Jr. Award for the Advancement of Justice and Human Dignity.
Linda Brown, daughter of Rev. Oliver Brown, a plaintiff in the 1954 Supreme Court decision Brown v. Topeka Board of Education; keynote
The 2009 Commemoration included three renowned Utah civil rights activists as keynotes: France Davis, David Dominguez, and Rocky Anderson. Clusters of presenters and performers featured many aspects of civil rights in Utah, such as the role of the arts, the role of the media, and the role of the LDS Church, especially blacks receiving the priesthood after nearly150 years of exclusion.
Among the many speakers at UVU were KRCL founder Stephen Holbrook, Diversity Times publisher Albert Jones, Utah NAACP President Jeanetta Williams, political cartoonist Pat Bagley, actor and gay rights/anti-war activist Jeff Key, Utah historian Ronald Coleman, and minority media expert Kenneth Campbell. UVU students and faculty also presented, including a panel on discrimination of the deaf. Two recent films shown and discussed included The Wisdom of Our Years and Nobody Knows . The first is an oral history of lives of Utah African Americans, and the second is about the exclusion of African men from the LDS priesthood and their transformative 1978 inclusion.
UVU's tradition of highlighting the arts in the Martin Luther King, Jr. Commemoration continued with student and faculty performances, exhibits, and an arts performance reception, all in our beautiful new library. Finding Voice , a musical written by Cache Valley survivors of domestic violence, was directed by Nancy Cannon and performed by UVU students. This moving ethno-drama related women's true experiences of despair and healing. Finally, Ogden's jazz octogenarian Joe McQueen brought his saxophone and played for us, and UVU's own poet/sonosopher Alex Caldiero performed black poetry in the Commemoration's grand finale.
Delores Huerta, Co-Founder of The United Farm Workers; keynote
Marian Jackson was awarded last year's Martin Luther King, Jr. Commemoration Award for the Advancement of Justice and Human Dignity. Marian is an educator whose work with migrant school children and farm workers brought them hope and assistance, and in doing so she exemplified the principles of Martin Luther King, Jr.
Vincent Harding
Author of Martin Luther King: The Inconvenient Hero; keynote
UVSC Black Student Union
Received the fourth annual Martin Luther King, Jr. Award for the Advancement of Justice and Human DignityMarlene Neptune
Former president of the UVSC Black Student Union, received the first Martin Luther King, Jr. Student/Alumni Award
Morris Dees
Co-founder and Chief Trial Lawyer, Southern Poverty Law Cente; keynote
Ingrid Guzman
Director of Centro Hispano, received the third annual Martin Luther King, Jr. Award for the Advancement of Justice and Human Dignity
John Echohawk
Co-founder and Executive Director, Native American Rights Fund; keynoteMr. Echohawk and NARF were the recipients of the second annual Martin Luther King, Jr. Award for the Advancement of Justice and Human Dignity
Joseph Vogel
of UVSC also received a Special Commendation for the Advancement of Free Speech
Yolanda King
Actress, Author, and Activist (Daughter of Dr. Martin Luther King, Jr. and Coretta Scott King); keynoteFirst annual recipient of the Martin Luther King, Jr. Award for the Advancement of Justice and Human Dignity


text:
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Brothers In Arms seeks to pull away from the clichéd mass of World War 2 shooters and put you in a first person World War 2 historical experience. Covering seven days, starting at midnight on D-day, you play an Allied paratrooper Sergeant from the 101st Airborne leading his squad through enemy lines. The squad is responsible for helping secure the area for the landing army and the events are based on history. Your squad is separated by fireteams, one of which is a tank in some missions. As you play as Sgt. Matt Baker you are free to assist either fireteam, or blaze your own path. Your squadmates are all unique and identifiable, helping to push this game to the next level of story telling.


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Forums >Running 101>new to net. inquiriousness aplenty
i can't hang
Passion is a rather frightening thing because if you have passion you don't know where it will take you.
When it's all said and done, will you have said more than you've done?
The voice of mile 18
so i can just ask questions and chime in whenever i feel like it? thats what this place is?
Member Since 2008
Now that was a bath...
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Wednesday, March 12, 2014
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"Curiosity," is the latest Mars Rover scheduled to land on Mars in the early morning hours of August 6. North Carolina Museum of Natural Sciences is hosting a late night event for the public to experience this once in a lifetime opportunity, complete with live feeds. News 14 Carolina's Marti Skold talks to Tamara Poles, with the NC Museum of Natural Sciences.


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Talk:Riot at the 1994 Quidditch World Cup
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Ok, so I was editing the "Background: Death Eaters" section and I was trying to make a link for half-bloods and Muggleborns, but it came up red and wouldn't work for me. Could somebody else, who is more knowledgeable about links then I am, fix this? Many thanks.
P. S. Muggles is fine. RolandaSmithson 02:41, July 7, 2010 (UTC)
- I fixed them. I intended it to say Halfbreeds, when I wrote it in February. They accept Half-Bloods, just not as highly. --JKoch(Owl Me!) 02:44, July 7, 2010 (UTC)
Shouldn't this have an event infobox, rather than a battle infobox? Can I/someone change that? --Emmy (★) 13:07, November 1, 2010 (UTC)


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Featured News - Current News - Archived News - News Categories
Junior Purple Eagles fundraiser
by jmaloniFri, Feb 4th 2011 02:00 pm
The Niagara Junior Purple Eagles 12U baseball team will hold an adult fundraiser, Saturday, Feb. 5, from 7 to 11 p.m. at Elks Lodge No. 346, 1805 Factory Outlet Blvd., in Niagara Falls.
Featured will be food, beer, wine and pop, plus live entertainment. A basket auction and 50/50 split drawing will also take place. Tickets are available at the door for $20 per person.


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What's New
- New option to show the top status bar whilst playing Hiqup- New option to turn off the background animations
- Tweaked piece selection code for greater accuracy
- Level 3, Board 6 now has medal requirements in correct order
- Reset button added to game screen for quick restart of a board without having to view 'Board Details' screen
App Description
NOTE: Works correctly on OS 3.0The peg-jumping brain-buster!
Give peg solitaire a fiendish twist and you have Hiqup, a fresh logic puzzler.
It's a devilish game that comes in easy, thought provoking, tough and down right serious. In standard peg solitaire you move your piece diagonally or horizontally, in Hiqup there are different pieces that move in different ways and you'll also encounter bombs, black holes, teleports, free jumps and special spaces that must be filled to complete boards.
Pit your wits against 47 original boards exclusive to Hiqup, as well as 10 standard peg solitaire boards from around the world.
Hiqup's quick tutorial gives you the basics and soon you're jumping pieces to get one to a teleport as the game racks up another notch whilst you aim for gold, silver and bronze on each board.
You can listen to your own music whilst playing Hiqup and it's packed with sound effects. If you need it, there is a help section to keep you on track and the background scenery is blissful.
**Crashes After Installation**
If you are experiencing crashes with Hiqup after installation, first of all try rebooting your iPhone / iPod Touch by holding down the home button and top button on your device. It appears that some app installs aren't being completed correctly which leaves them in a state where they crash frequently. Rebooting your device should resolve this and allow the game to be played without the random crashes. Please note that this can happen randomly with the installation of any app and is not something peculiar to Hiqup. We've included this information to hopefully help with any frustration you may encounter that is outside our control.
App Changes
April 23, 2011 New version 1.1
September 13, 2008 Initial Release


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(Photo Courtesy of TradeWinds)
The children pledged to run for donations of food, pet supplies and blankets to be delivered to the Gary Animal Control Facility in the hope of prolonging the lives of the abandoned animals until they can be fostered and eventually adopted. Both TradeWinds Staff and the summer campers have been busy collecting donations for the ten-lap run. At the completion of each lap runners were splashed with a non-toxic paint.
TradeWinds' Director of Programs Lisa Previs said that community awareness and involvement is one of the hallmarks of the TradeWinds' children's programs. "Despite their own special needs, these children are looking outward and making a difference – literally a life and death difference—on behalf of these unfortunate animals. It's their hope that their time, talent and compassion will save the lives of the dogs and cats until they can be placed in safe and loving homes."
Children attending the TradeWinds Summer program come to camp with various abilities and disabilities. "Tolerance and acceptance of one another is the one of the fundamental keys of the program," said Previs, "and thinking about and caring for others is a very important life lesson."
The fundraiser took place at TradeWinds' main center in Gary, IN. TradeWinds is a non-profit agency that supports children and adults with disabilities whose mission is "Serving people with special needs by empowering them to realize their full potential." For more information visit tradewindsnwi.org
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LAURA WALUSZKO Region News Team |
SCOTT ROSENBERG Region News Team |
BRENT BROWN Region News Team |
JAY STEVENS Region News Team |
KARL BERNER Region News Team |
ANNIE FOX Region News Team |
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Definition of turnaround in English:
Line breaks: turn|aroundPronunciation: /ˈtəːnəraʊnd
(also turnround)
- 1An abrupt or unexpected change, especially one that results in a more favourable situation: it was a remarkable turnaround in his fortunesMore example sentences
- In each of these situations, an unexpected turnaround causes someone's life to change dramatically, and for the better.
- The turnaround is the result of an attitude change at the club and not just from the players.
- This turnaround is largely the result of the Baby-boomer bulge entering retirement and being succeeded by steady-state Baby-bust workforce.
- 2The process of completing or the time needed to complete a task, especially one involving receiving something, processing it, and sending it out again: a seven-day turnaroundMore example sentences
- As systems become more accessible, customers demand a faster turnaround.
- Carter maintains that the turnaround he was hired for was complete, and that he left voluntarily.
- RTE says the turnaround time is a fraction of a second.
- 2.1The process of or time taken for unloading and reloading a ship, aircraft, or vehicle: short hops with quick turnarounds and limited in-flight serviceMore example sentences
- They did a quick turnaround of the aircraft, and thus nobody got any food.
- It is looking at a faster turnaround of vehicles unloading waste and collections of items to be recycled.
- It is hoped the development will allow a quicker turnaround time for ships coming into Sligo Harbour, particularly as the winter brings shorter daylight hours.
- 3North American A space for vehicles to turn round in, especially one at the end of a driveway.More example sentences
- Already a new hard standing area for lorry turnarounds has been laid at Rolawn's Elvington headquarters where the York depot will be based.
- There was only the limousine, disappearing once more around the corner of the estate wall toward the turnaround.
More definitions of turnaround
Definition of turnaround in:- The US English dictionary
- The US English Synonyms


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Ruffle Tank is not your typical dog tank. It features two rows of ruffles in bright cheery colors and is perfect for outings.
This stylish and trendy tank features angled rows of ruffles on the back, a poly/cotton body with ruffle sleeves and hem. Easy pullover design with high-cut belly keep pets dry and comfy.
Material: 65% Polyester; 35% Cotton Care: Machine wash in cold water on gentle cycle. Line dry.


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Date: February 13, 1970
Author: unknown
Biographical/Historical abstract:
Additional contributor:
Description: This February 13, 1970, article from The Carolinian, the student newspaper of The University of North Carolina at Greensboro (UNCG), discusses the possibility of a forthcoming statewide desegregation order covering the state university system from the United States Department of Health, Education, and Welfare (HEW). HEW had requested a report within sixty days on actions that would promote desegregation and minority faculty recruitment. HEW suggested that the university system should add equal opportunity statements to all publications, review its recruitment program, cooperate with black schools, increase faculty recruitment efforts, and work with "high risk" populations.
Format of original: Newspaper Clippings
Collection: Carolinian
Repository: The University of North Carolina at Greensboro
Item#: 1.3.852
Rights: It is responsibility of the user to follow the copyright law of the United States (Title 17, U.S. Code). Materials are not to be reproduced in published works without written consent, and any use should credit Civil Rights Greensboro and the appropriate repository.


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The internet-connected mobile phone may prove to be one of the most notable consumer innovations in the past century, but it may also be a headache for brick-and-mortar retailers who, over the past decade, have had to figure out how to adapt to a world increasingly engaging in ecommerce.
The reason the mobile phone is keeping retail executives up at night: comparison shopping on steroids. Thanks to comparison shopping websites, and dedicated comparison shopping apps, consumers can simply walk into a store, scan an item's barcode and search the web for a better price.
Read more...
by Patricio Robles 17 December 2010 10:07am 1 comment


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The practice of locating two similar Wikipedia articles, one useful and the other relatively frivolous, where the frivolous article is substantially longer and more involved than the useful article. Also: wikigroaning, Wiki-groaning.
Example Citations:
There's a new sport on the Internet: competing to come up with the best examples of how Wikipedia, the Web's home-grown reference source, is skewed towards pop-culture topics. For instance, the West Wing of the White House merits a 1,100-word entry on Wikipedia, while "The West Wing," the Aaron Sorkin TV drama, has an 6,800-word write-up. This game already has a name: "Wiki-groaning."
—Jamin Brophy-Warren, "Oh, That John Locke," The Wall Street Journal, 16 June 2007
—Jamin Brophy-Warren, "Oh, That John Locke," The Wall Street Journal, 16 June 2007
There was once an Englishman named John Locke, who had some interesting thoughts about political theory. There is also a character named John Locke on the TV show Lost.
Which one has the longer entry on Wikipedia?
To the surprise of nobody, it's not the enlightenment philosopher. This is what we call "wikigroaning": the art of highlighting Wikipedia's bias toward things that don't matter.
—Ivor Tossell, "Duality of Wikipedia," The Globe and Mail, June 15, 2007
Earliest Citation:
The premise is quite simple. First, find a useful Wikipedia article that normal people might read. For example, the article called "Knight." Then, find a somehow similar article that is longer, but at the same time, useless to a very large fraction of the population. In this case, we'll go with "Jedi Knight." Open both of the links and compare the lengths of the two articles. Compare not only that, but how well concepts are explored, and the greater professionalism with which the longer article was likely created. Are you looking yet? Get a good, long look. Yeah. Yeeaaah, we know, but that is just the tip of the iceberg. (We're calling it Wikigroaning for a reason.)
—Jon Hendren, "The Art of Wikigroaning," Something Awful, June 5, 2007
—Jon Hendren, "The Art of Wikigroaning," Something Awful, June 5, 2007
For more Wikigroaning fun than is probably good for your day job, see the WikiGroaning site.
Related Words:


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Article ID: 2554629 - View products that this article applies to. On This PageIntroductionUpdate Rollup 1 for Windows Small Business Server 2011 Essentials is available. This article describes the new feature and some of the updates that are included in this update rollup. Important This update rollup contains server-side fixes. In addition to this update package, you must also install the client-side package on all client computers. For more information about the client-side package, click the following article number to view the article in the Microsoft Knowledge Base: 2554637
The client-side package for Update Rollup 1 for Windows Small Business Server 2011 Essentials, for Windows Home Server 2011, and for Windows Storage Server 2008 R2 Essentials is availableFeature that is included in Update Rollup 1 for Windows Small Business Server 2011 EssentialsThis update adds an alert that reminds you to enable Microsoft Update. The alert appears after you install Windows Small Business Server 2011 Essentials and complete the "Getting Started" tasks on a computer. The alert displays the following message:Major issues that are resolved by this updateIssue 1Consider the following scenario:
Cannot retrieve the user account information An unknown error prevented the wizard from retrieving the user account information. If this problem persists, restart the server, and then try again.
Issue 2You cannot register a Remote Web Access domain name that contains two or more root domain levels (such as testuser.co.uk). Additionally, you receive an error message that resembles the following:The domain name is not valid This domain name is invalid. Ensure that the domain name and the extension are correct, and they try again. Issue 3In the Alert Viewer window, you select an alert, and then you click Ignore the alert to stop receiving notifications for this alert. However, the notifications still appear.Issue 4Consider the following scenario:
Issue 5When the machine certificate is changed incorrectly or is removed, you are not prompted to take any troubleshooting measures. After you install this update, an automatic process tries to resolve this issue. If this issue cannot be resolved automatically, the dialog box prompts you with a link to a troubleshooting website. The website provides the latest solutions and updates for the kind of issue that you are experiencing.Issue 6A backslash (\) is displayed incorrectly in Korean or Japanese content.Issue 7"Connect site" is translated incorrectly in a non-English dashboard.Issue 8Some important non-English instructions or guides are truncated in a non-English dashboard or wizard.MORE INFORMATIONUpdate informationHow to obtain this updateTo download this update, visit the following Microsoft website:Windows Update
PrerequisitesTo install this update, you must be running Windows Small Business Server 2011 Essentials.Registry informationTo use the update in this package, you do not have to make any changes to the registry.Restart requirementYou may have to restart the computer after you apply this update.Update replacement informationThis update does not replace a previously released update.Removal informationTo remove this update, use the Add or Remove Programs item in Control Panel. Additionally, you must uninstall the client-side package (KB2554637) from all client computers.Note The new "Microsoft Update is not enabled" alert must be manually removed from all client computers. REFERENCESFor more information about software update terminology,
click the following article number to view the article in the
Microsoft Knowledge Base: 824684
Description of the standard
terminology that is used to describe Microsoft software
updatesPropertiesArticle ID: 2554629 - Last Review: September 14, 2011 - Revision: 4.0


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Mobile Email MyUNIverse eLearning A-Z Index Calendar Directory Contact Employment Visit UNI
UNI Faculty Leadership in Sustainability Education Summer Institute 2014
Submitted by Anonymous on Thu, 06/19/2014 - 7:00amOpportunity for UNI tenure and tenure-track faculty to participate in UNI Faculty Leadership in Sustainability Education Summer Institute. Apply by Friday, March 21. Selected participants will receive $2,000 stipends.
Healthy Communities Film: "Searching for Shangri-La"
Submitted by Anonymous on Mon, 04/28/2014 - 6:00pmDesigning Healthy Communities is a four-part series that takes a comprehensive look at the impact America's built environment has on public health, and at the people and communities working to turn things around through innovative solutions.
In the final episode, "Searching for Shangri-La," Dr. Jackson searches past and present America for model communities large and small that embody the intricate balance of health promoting design and human needs. Does the perfect community exist?
Sustainability Book Club Meeting
Submitted by Anonymous on Thu, 04/24/2014 - 2:30pmJoin faculty in discussing Histories of the Dustheap. Histories of the Dustheap uses garbage, waste and refuse to investigate the relationships between various systems and shows how this most democratic reality produces identities, social relations and policies. This is the third meeting of a three-part discussion series. Pre-registration required.
UNI Earth Week Bike Ride
Submitted by Anonymous on Wed, 04/23/2014 - 5:00pmJoin the RRTTC, Cedar Valley Cyclists, and UNI Cycling Club in a bike ride around Cedar Falls to celebrate UNI's Earth Week. The ride will start and end at Mulligan's on 18th Street in Cedar Falls. Helmets are required for participation. Pre-registration required. All registered participants will receive a free t-shirt.
UNI Earth Day Campus Cleanup
Submitted by Anonymous on Tue, 04/22/2014 - 4:30pmUNI Volunteer Tuesdays and Green Iowa AmeriCorps will partner for an Earth Day Campus Cleanup during UNI's Earth Week Celebration. Pre-registration is required.
UNI Earth Day Highway Cleanup
Submitted by Anonymous on Tue, 04/22/2014 - 2:30pmUNI Volunteer Tuesdays and Green Iowa AmeriCorps will partner for an Earth Day Highway Cleanup as part of UNI's Earth Week Celebration. Participants will pick up trash from a section of Highway 20. Pre-registration is required.
UNI Earth Day Celebration
Submitted by Anonymous on Mon, 04/21/2014 - 11:00pmJoin students, faculty and staff in a campus-wide UNI Earth Day Celebration. Visit www.rrttc.com for more information.
Earth Week Yoga Class
Submitted by Anonymous on Mon, 04/21/2014 - 4:00pmIn honor of the 2014 UNI Earth Week Celebration, UNI students are invited to participate in an afternoon of relaxing yoga. This free event will feature certified UNI yoga instructors. All participants will receive a water bottle. Classes will be held at 5 p.m. and 5:30 p.m. Pre-registration is required.
Healthy Communities Film: "With My Own Two Wheels"
Submitted by Anonymous on Mon, 04/07/2014 - 6:00pmCan a simple 19th century technology change the world? For most North Americans, a bicycle ride or commute is a lifestyle choice. For countless others across the globe, each pedal stroke is progress out of poverty, toward an education and over the mountains of social and cultural discrimination.
"With My Own Two Wheels" profiles the lives of five people and portrays the powerful difference a bicycle has made for each of them and their communities. The film can be used to better understand their life circumstances, the power of an "appropriate" human-scale technology in an increasingly hi-tech world and to inspire discussion on how we can each contribute to improving the lives of people around the world, even in simple ways.
Healthy Communities Film: "Troubled Waters"
Submitted by Anonymous on Mon, 03/31/2014 - 6:00pmThe Emmy Award-winning "Troubled Waters: A Mississippi River Story" tells the story of the unintended yet severe consequences of farming along the Mississippi and the efforts being taken to reverse this damage. America's heartland boasts some of the world's most productive farmland, but this bounty has come with a price. Excess crop fertilizers are contaminating the nation's rivers, lakes and aquifers, while at the same time precious soil is washing away.


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1121 E. North Avenue Milwaukee, WI 53212 Phone Numbers: (414) 267-6500 (Main Appointment Line) (414) 267-6560 (Referrals) (414) 267-6570 (Medical Records) (414) 267-3893 (Fax Number)
Hours: Monday through Friday, 9:00 a.m. - 5:00 p.m.
Welcome to Columbia St. Mary's Family Health Center. We are proud to be part of Columbia St. Mary's and affiliated with the Medical College of Wisconsin.
The Columbia St. Mary's Family Health Center is a residency training program. After completing medical school, all physicians are required to spend several years in training in their chosen specialty.
Our physicians and nursing staff work as a team to give you the best care possible. When a resident physician finishes his/her training with us, your care will be assigned to another physician on the same team.
Our family physicians seek to provide continuing, compassionate and personal care to families and the community. Our family physicians understand that health and disease involve the mind, body and spirit. We have skills in diagnosing and treating illness, in performing diagnostic and therapeutic procedures, and especially in anticipating patient needs and designing services to meet those needs. Working with all ages and ethnic groups, we focus on keeping you healthy, not just helping you get well.
Our physicians provide a broad range of services including:
Columbia St. Mary's Family Health Center accepts many types of insurance. You should make sure your insurance company will pay for physician visits and services you receive here. If your insurance does not pay for services or you do not have insurance and you wish to pay for services yourself, you will need to make a $40.00 payment when you register. This payment will be applied to your bill. Columbia St. Mary's Family Health Center does offer a sliding fee for those not covered by insurance. Please ask a receptionist for more information. You may receive two bills. The physician visit bill will come from the Medical College of Wisconsin. The other bill will come from Columbia St. Mary's and is for other additional services that may have been provided during the visit. If you have any questions, please call the phone number on the bill. Electronic Health Records and Your Privacy Columbia St. Mary's Family Health Center maintains your records electronically. Your records are confidential. Columbia St. Mary's has policies in place to protect your personal health information.
The following tips will make your visit to the office easier. Please be sure to bring:
If you need to cancel an appointment, please call the day before your appointment to reschedule your visit.
If you are late for an appointment, it may be necessary to ask you to wait or to reschedule your appointment.
If you have more than three no-shows for an appointment in a calendar year without calling in advance, you will be discharged from our health center.
Patients under the age of 18 must be accompanied by a parent or have parental consent. If you need to see a specialist, our Referral Coordinators will help you with your referral before you leave the office
To request an appointment, please call (414) 267-6500 or send an email.
To speak with a nurse after hours, please call: (414) 267-6500. For life threatening emergencies, call 911.


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Melissa Gorga's Fans Turn Against Her; Grand Conspiracy to Defame Teresa (29 Against 1); Jacqueline Laurita Rejects Teresa Giudice's Apology (Updated 9/4/2013)
"Kim told me that she and Lysa expected to be on the show by next season. They told me they would be taking Teresa and Kathy's place. So we should show our support by tweeting about them too." – ExMarcoSistersFan, May 4, 2013, Faux Reality Entertainment
Melissa Gorga Twitter Fan Site Shuts DOWN!
C'est la Vie: Potpourri
April 24, 2012
Today, in surprising news, the Marco Sisters Twitter fan site (@MarcoSistersFan) owner shut the site down, claiming that Melissa Gorga, sister in law of Teresa Giudice, has a double persona.
Melissa first became famous for joining the Real Housewives of New Jersey, where Teresa was already starring on, in an effort to defame and publicly humiliate Giudice.
The owner of the Twitter site acknowledged Melissa's malicious motives in joining the show and also stated that she found the first episode to be "extremely disturbing."
The twitter site owner also states that Melissa's husband and Teresa's brother, Joe, is a "vile man who will stop at nothing to bring his sister down unless he gets camera time."
Season four of the series premiered Sunday to the Bravo network's highest ratings, however many viewers were disappointed with the Giudice bash fest by all four other castmates, including both Melissa and Joe.
I believe that this is an interesting development for this family. I'm not surprised and will be happily awaiting for others to jump ship as the season and true motives and intentions continue to come forward.
From MarcoSistersFan on Twitter:
I am sorry to say that I will be closing down this [Twitter] account very shortly. After some time, I've become aware of Melissa Gorga's double persona. She has proved to be a narcissist and has showed an extremely passive aggressive attitude. I also found Joe Gorga's actions in the premiere episode [of season 4] to be extremely disturbing. This family will stop at nothing to bring Teresa down. Joe Gorga is a vile man who will stop at nothing to bring his sister down. Teresa has showed us viewers that she can rise above the pettiness.
Melissa came on the show with the intent to hurt, and that's something I can no longer support. Her makeup artist should be reprimanded for talking ill of her sister-in-law.
Melissa Gorga, you came on the show to air out your dirty family laundry and did not care who got hurt on your path to "fame." You're a lousy singer. Your husband is a famewhore; he just wants to be made into a 6th housewife!
I am tweeting to let you all know that Melissa and Joe Gorga are not innocent. They try to portray themselves as such, but it is an ACT! Melissa Gorga and Joe Gorga are phonies. They want America to believe they are victims when in reality they are SCUM.
This season [season 4] will put more things into perspective for all you fans of the Gorgas! Team Teresa! Teresa Giudice, I am so sorry if I ever wrote anything negative about you. I see the truth now! You're amazing, as a mother, sister, daughter, friend, etc. Don't ever let anybody tell you otherwise! Shine on!
Caroline controls Jacqueline. It's sick!
I once tweeted Jacqueline something in defense of Teresa, and I was immediately DM'ed by the Marco sisters asking to delete my tweets because Jac was their friend. They never once asked me to delete anything negative I wrote about Teresa!
RHWGOSSIP, give it a rest, and take your head out of the Gorga's ass! We see the truth! RHWGOSSIP, you would love the world to believe that everyone HATES Teresa, but the truth I see is that she clearly has a bigger fan-base than you can fathom!
Yes, I did lie about @bino989 sending me DMs. I'm sorry. I was told that you and that blogger site were harassing the Marco sisters! I was used as a shield to protect them!
Lysa Simpson, why don't you tell everyone how you had no problem letting me speak in defense of you guys and how you had no problem if I threw Teresa under the bus. Lysa believes that Bino and AlllAboutTRH are the ones who were starting the most mess for them.
I am not proud of my actions. I was just merely a fan in the beginning trying to protect those I was a fan of. I'm glad I realized what a mistake that was.
Note: MarcoSistersFan is now ExMarcoSistersFan on Twitter.
ExMarcoSistersFan @MarcoSistersFan
Melissa Gorga and Joe Gorga are phonies. They want America to believe they are the victims when in reality they are SCUM
April 25, 2012
Meho Whorga @MehoGorga
@amnicoli @AsianPosh1 @MarcoSistersFan she said she got a DM from Lysa asking her 2 take a tweet she made about Tre down it was being nice
April 25, 2012
ExMarcoSistersFan @MarcoSistersFan
@kimpirrella @marcosisterfan Coward am I??? I wasn't so much of a coward when I helped defend you guys against the "group of nasty people"
April 25, 2012
Kim Pirrella @kimpirrella
Any of our followers following @marcosisterfan feel free to unfollow. apparently the cowardly lion has flipped they're lid.
April 25, 2012
UPDATE on 4/27/2012: MarcoSistersFan shutdown her Twitter account in disgust over Melissa Gorga and her sisters' behavior. The fan site owner then needed a break from all of this nastiness on Twitter, so she took a hiatus to regain composure. The Marco Sisters then DM'd her to DELETE her account [direct messages here]! This was the breaking point and when she decided to reveal the truth about these sisters.
There seems to be one common denominator which which permeates all Teresa's failed relationships. Teresa and Joe were close. Then Melissa entered the picture. Kathy and Teresa were close. Enter Melissa. Jacqueline, Caroline and Teresa were close. Enter Melissa. Caroline has said that her problems with Teresa stem from more than the cookbook. She has alluded to "rumors" that got back to her. There didn't seem to be any rumors until season three. Enter Melissa. If I were the Church Lady I'd say, could it be Satan? But, since I'm not, I'll just say, could it be Melissa? [Njonlooker, AllAboutTRH.com, April 26, 2012]
[In season 2]Melissa AND Joe wanted to come on to surprise Teresa and be on-camera friends with Danielle. I wish that did happen because maybe Caroline and Jacqueline would not be believing all of Melissa's lies like you will see in season 4… Melissa knows how to lie and get what she wants, but the truth will come out… Melissa is a complete fake. She has tried to get on the show; it never happened until she stalked Danielle and made a video WITH Joe (nice brother) saying they will 'destroy Teresa'. Yet, they call Teresa garbage for working to support her family and keep a beautiful roof over her family's head… Like Danielle can confirm, Mel was dying to film scenes with her similar to the ones she does with her sisters and Kathy, where she fabricates lies and bitches about Tre… Joey G and Melissa filmed a tape where they, in the style of the Sopranos, promised Bravo execs they would 'expose' and 'destroy' Teresa. They also guaranteed to give Tre what she has given them '…their whole life'. [Insider Commenting at Reality Tea, August and September 2011]
Melissa's strategy this season was to play victim during filming. She is just a better 'actress' than some of the other girls. She really is playing the game of the 'victim.' Melissa is very happy the way things turned out. She couldn't wait to get in the group and turn them all against Teresa. [Inside Source at Reality Tea, May 6, 2012]
I can only imagine what this season's reunion will be like. Teresa, please don't feel you have to explain yourself any more, because it's obvious that nothing you say is good enough for these women. They don't like you, for whatever reason, and it's time to move on. If you can stay on the show and be happy knowing that the rest of the cast doesn't like you, then PLEASE stay, because you have a lot of fans. However, if it's too painful, then it's time to move on. You've reached out and done what you could and have been slapped in the face for it. Time to take a page out of everyone else's book—smile in their faces then rip them in your talking head interviews. Don't forget to roll your eyes and make sarcastic wisecracks too, ala Mama Manzo. [cammierari, AllAboutTRH.com, April 28, 2012]
When Danielle brought up Melissa at the reunion, Teresa figured out that it was Melissa and Kathy who were leaking her private information to tabloids and online. Melissa was making money off of Teresa! So why would she turn around and tell Melissa, Joe and Kathy ANYTHING about herself? So THEY can profit off of it? At least this way [selling her apologies to In Touch], Teresa can ensure the only one profiting off her misfortune is Teresa and her children. They are just angry they can't make money off her anymore. [Say What??, AllAboutTRH.com, May 3, 2012]
If Teresa only apologized in private then the other four would lie and say it never happened. Now her sincere apologies in the blog and magazine are public record. Of course, now the other four are saying it wasn't the right kind of apology, with, of course, means only they can decide what a "real" apology should contain. Caroline seems to think that Teresa is trying to rehabilitate her image, when it is Caroline and friends who have taken a major hit. Move on Teresa, you did good. [villadeste, AllAboutTRH.com, April 28, 2012]
Grand Conspiracy to Defame Teresa (29 Against 1)
The Marco sisters and their cronies will not be happy until Teresa is no longer on RHONJ, her husband is in jail, she is broke, and her four children are homeless. It was Melissa and her evil sisters who instigated this whole thing that turned the show into such a train wreck. Theirs is a well-planned conspiracy to ruin Teresa's reality career so that Melissa can have the spotlight along with her husband and sisters. Caroline signed on to the plan because she wants Teresa off the show just as bad as Melissa. Jacqueline is a sucker and fell for the lies being fed to her by the Marcos.
So in this grand conspiracy to defame Teresa, we have the following, lead by the Marco sisters, working to bring Teresa down (28 against 1):
Joe Gorga (blood relative of Teresa and her children who told her that "you need to fall")
Kathy Wakile (blood relative of Teresa and her children)
Rosie Pierri (blood relative of Teresa and her children
Richie Wakile
The Wakile Children (blood relatives of Teresa and her children)
Melissa Gorga
Donna Marco (Melissa's mother)
Lysa Simpson (Melissa's sister)
Kim Pirrella (Melissa's sister)
Joe Pirrella (Kim's husband)
Lou Marco Orlick (Melissa's aunt)
George Miguel Costa (Melissa's makeup artist)
Tara Bogota (Melissa's cousin)
Caroline Manzo
Albie Manzo
Christopher Manzo
Lauren Manzo
Jacqueline Laurita
Chris Laurita
Ashlee Holmes
Bonnie Grippe (Jacqueline's mother)
Greg Bennett
Sheila Marino-Giudice (Teresa's SIL who finally came to her senses and left the dark side to support Teresa)
Kim Granatell
Monica Chacon
Kim Hiza
Tom Murro
Caroline Self
Cat Rodriguez
Andy Cohen
Jacqueline Laurita Conspires with the Marco Sisters and Rejects Teresa Guidice's Apology
"I once tweeted Jacqueline something in defense of Teresa, and I was immediately DM'ed by the Marco sisters asking to delete my tweets because Jac was their friend. They never once asked me to delete anything negative I wrote about Teresa!" – MarcoSistersFan, April 25, 2012
"@JacLaurita You look beautiful!" – Donna Marco (Melissa's mother), April 25, 2012
Jacqueline and Teresa's Tweets on April 25, 2012:
Jacqueline conspired with the Marcos (which includes Joe Gorga) and the Lauritas/Manzos (the head of the snake being Caroline) to destroy Teresa's well being and livelihood. Jacqueline shared with her conspirators private discussions that she had with Teresa when they were friends. She is a backstabber and the most disloyal of friends. She 'direct messages' people on Twitter with negative comments about Teresa and then blocks them so that can't reply. Jacqueline has been brainwashed by the Marco sisters and Caroline Manzo. She is not her own person. All of these housewives and their husbands, their children and their other relatives and friends ganged up on Teresa and talked trash about her. And SHE apologizes and they refuse to accept her apology? Caroline, Jacqueline, Melissa, Kathy, etc. need to step back and apologize for their behavior toward Teresa.


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Hey all, this is in no means anyway to try to be in charge, but as a new member and fisherman here. I would really like to meet new friends and members in this area and see about getting a local board going for us to swap help and tips. This is our state and who knows it better right.
Well if you get on here and see this say hi, and where your from. And maybe we can get our knowledge flowing and help. Ill start.
My name is Chris Prine Jr.
I am 27 years old, turning 28 July 9th.
Fished a little bit when I was really young, and started back up 3 weeks ago in hopes to learn this sport and the fun and joy so I can help my son learn this. He just turned 1 a few weeks ago.
I live in West Monroe, La.
I hope to get to know you all and we can start planning a weekend or just start sharing ideas to get to know each other more.
Prince01 I am a brand new member up here in Shreveport and its good to see that you are trying to get a Louisiana delegation started. I am a novice fisherman at best, but I am passionate about learning the "2nd oldest profession"(we all know what the first one is...lol) Anyway, I mostly fish in Cross Lake, but I am going to try to get to Red River this weekend. Look forward to hearing from you all.


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Quick Facts
- NAME: Helena Bonham Carter
- OCCUPATION: Film Actress, Theater Actress, Television Actress
- BIRTH DATE: May 26, 1966 (Age: 47)
- PLACE OF BIRTH: London, England
- ZODIAC SIGN: Gemini
Best Known For
Helena Bonham Carter is a British actress known for her roles in historical dramas, as well as quirkier movies including Fight Club and Dark Shadows. She is married to director Tim Burton.
Think you know about Biography?
Answer questions and see how you rank against other players.
Play NowHelena Bonham Carter. (2014). The Biography Channel website. Retrieved 05:42, Mar 11, 2014, from http://www.biography.com/people/helena-bonham-carter-9218984.
Helena Bonham Carter. [Internet]. 2014. The Biography Channel website. Available from: http://www.biography.com/people/helena-bonham-carter-9218984 [Accessed 11 Mar 2014].
"Helena Bonham Carter." 2014. The Biography Channel website. Mar 11 2014, 05:42 http://www.biography.com/people/helena-bonham-carter-9218984.
"Helena Bonham Carter," The Biography Channel website, 2014, http://www.biography.com/people/helena-bonham-carter-9218984 [accessed Mar 11, 2014].
"Helena Bonham Carter," The Biography Channel website, http://www.biography.com/people/helena-bonham-carter-9218984 (accessed Mar 11, 2014).
Helena Bonham Carter [Internet]. The Biography Channel website; 2014 [cited 2014 Mar 11] Available from: http://www.biography.com/people/helena-bonham-carter-9218984.
Helena Bonham Carter, http://www.biography.com/people/helena-bonham-carter-9218984 (last visited Mar 11, 2014).
Helena Bonham Carter. The Biography Channel website. 2014. Available at: http://www.biography.com/people/helena-bonham-carter-9218984. Accessed Mar 11, 2014.
Helena Bonham Carter was born on May 26, 1966, in London, England. Her film debut was in Lady Jane in 1985 and she became well-known for her roles in historical dramas including Howard's End and A Room with a View. After appearing in his 2001 remake of Planet of the Apes, Carter married director Tim Burton and has made frequent appearances in his films. They have two children.
Career Highlights
Actress Helena Bonham Carter was born on May 26, 1966, in London, England. Helena Bonham Carter is perhaps best known for playing quintessential English heroines. She made her cinematic debut as Lady Jane Grey in Lady Jane (1985). Later film credits include Hamlet (1990), Howard's End (1992), Mary Shelley's Frankenstein (1994) and Twelfth Night (1996).
In 2001, Bonham Carter appeared in the remake of Planet of the Apes directed by Tim Burton. Not long after the film's release, the two became involved and had their first child together in 2003. The couple worked on another remake, Charlie and the Chocolate Factory (2005) starring Johnny Depp. She also lent her voice to the title character of Burton's dark animated tale, Corpse Bride (2005).
In 2007, Bonham Carter co-starred in Sweeney Todd: The Demon Barber of Fleet Street with Johnny Depp, which was directed by Burton. The film was an adaptation of a popular musical and both lead actors performed their own songs for the movie. Around this time, Bonham Carter and Burton also expanded their family. The couple welcomed their second child in December of that year.
Outside of her work with Burton, Bonham Carter most recently appeared in the box office hit, Harry Potter and the Order of the Phoenix (2007), the latest installment of the film adaptations of J. K. Rowling's best-selling Harry Potter book series.
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Most people get to know their co-workers well...and sometimes working together can even lead to romance. Just like in the office, many Hollywood stars find romance at work—or rather, on the set. Some of the most famous couples in Hollywood history met while making a film, including Richard Burton and Elizabeth Taylor, Joanne Woodward and Paul Newman, and Angelina Jolie and Brad Pitt. Here's a look at the famous actors and actresses whose chemistry set off sparks on the set.
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In true Albus Dumbledore fashion, Biography.com examines and provides insight on the cast of the illustrious Harry Potter film series, based on the popular books by author J.K. Rowling. Debuting with Harry Potter and the Philosopher's Stone and ending with the two-part Harry Potter and the Deathly Hallows, the eight-part film series continues to wow fans with its tales of witchcraft and wizardry. It also includes a gamut of stars, from Daniel Radcliffe, who plays the famous Harry; to Emma Watson, who plays Harry's best friend, Hermione; to Alan Rickman, known for his villainous role as Severus Snape; to Robert Pattinson, who plays the attractive Cedric Diggory, Harry's Triwizard Tournament rival; and more.
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text: content LE Magazine November 2007 Watercress Benefits for Cancer Protection, Vision, and Heart HealthBy Erika Alexia Tsoukanelis A startling 30-40% of cancers are directly linked to improper diet and related factors, according to a report published this year by the World Cancer Research Fund UK.1 Accordingly, there is no better time than now to diligently incorporate nature's most powerful cancer-fighting foods into your daily diet. The cruciferous vegetables such as broccoli, cauliflower, Brussels sprouts, and cabbage have long been held in regard for their anticancer effects. Their little-known cousin, watercress, also shows extraordinary potential in the realm of cancer prevention and management, as well as offering the culinary versatility of a delicious leafy green. The anticancer benefits of watercress may arise from its ability to increase the level of antioxidants in the blood and to protect DNA against damage.2 In fact, growing evidence suggests that watercress may lower the risk of prostate, colon, and breast cancers, and may counteract certain processes by which cancers proliferate and spread.3-7 Watercress is an excellent source of the antioxidants vitamins A and C, as well as vitamin K, an essential micronutrient for bone health. It is also a rich natural source of lutein and zeaxanthin, two carotenoid nutrients that are gaining attention for their ability to protect vision and support cardiovascular health.8 Given this wealth of health benefits, it is not surprising that Hippocrates, the father of modern medicine, built his first hospital in close proximity to a stream where watercress grew so that his patients would have ready access to this life-sustaining green.9 Cancer Protection Cruciferous vegetables, such as watercress and broccoli, are well known for containing glucosinolates, phytochemicals that are hydrolyzed to produce isothiocyanates, which have been studied for their anticancer effects. Dietary intake of these compounds has been shown to counter breast, lung, colorectal, head and neck, and prostate cancers.3-7 Watercress is also an exceptionally rich dietary source of nasturtiin, the precursor of phenethyl isothiocyanate (PEITC).10 This compound inhibits the liver's phase I enzymes, which are responsible for activating many carcinogens in animals, and induces the liver's phase II enzymes, which are associated with enhanced excretion of carcinogens. When human prostate cancer cells were exposed to PEITC, both proliferation (multiplication of cells) and tumorigenesis (production of tumors) were inhibited. This compound also triggered apoptosis, or the death of cancerous cells.11 Similarly, crude watercress extract was "significantly protective" against three stages of the carcinogenic process in human colon cancer cells. The stages investigated were initiation, proliferation, and metastasis (spread of cancer).12 Isothiocyanate compounds from watercress and broccoli were found to hinder the activity of matrix metalloproteinase-9, an enzyme that plays a role in progression of certain cancers by breaking down natural barriers in the body that impede the expansion of existing tumors. These watercress and broccoli-derived compounds were also shown to suppress a highly invasive breast cancer cell line.13 Furthermore, in laboratory models of cellular activity, watercress isothiocyanates restrained certain pro-inflammatory compounds that are associated with chronic inflammation and cancer.14 In addition, researchers at the University of Ulster recently published some of the most comprehensive and convincing work to date on the positive effects of raw watercress ingestion on certain biomarkers related to cancer risk. Sixty men and women, half of whom were smokers, participated in the study, which involved eating three ounces of raw watercress per day, in addition to the normal diet, for eight weeks. DNA damage to lymphocytes and plasma lutein, retinol, alpha-tocopherol, and beta-carotene were measured. Overall, there was a 17% reduction in basal DNA damage. Antioxidant blood levels increased, beta-carotene levels rose 33%, and lutein levels skyrocketed by 100%.2 Furthermore, smokers experienced greater DNA-protective effects from watercress than non-smokers. Watercress Carotenoids Benefit the Cancer Watercress is an abundant source of lutein and zeaxanthin, two carotenoids that may be particularly beneficial for the eyes and the heart. High dietary intake of lutein and zeaxanthin is linked to a lower risk of advanced age-related macular (eye) degeneration, the most common cause of adult blindness.15,16 One cup of raw watercress contains over 1,900 mcg of lutein and zeaxanthin,8 suggesting that watercress consumption might help prevent the occurrence of vision-robbing macular degeneration. Growing evidence suggests that lutein and zeaxanthin may also offer important protection for the cardiovascular system. Individuals with higher blood levels of lutein and zeaxanthin were found to have less atherosclerosis of the arteries of the neck than those with lower blood levels. Furthermore, people with higher blood levels of lutein were less likely to succumb to a heart attack than those with lower levels.16 Enjoying Watercress Preparing watercress is simple. After trimming the stems, rinse the greens in cold water and dry on a paper towel or in a salad spinner. Use immediately, or store in a closed container in the refrigerator for up to four days. Watercress can take the place of lettuce in any salad, sandwich, or other recipe, and can be used as a nutritious garnish. Watercress can also be enjoyed lightly steamed, stir-fried, or in a soup. Uncooked watercress may have greater cancer-fighting power than cooked watercress, as cooking inactivates the myrosinase enzyme that is responsible for hydrolyzing glucosinolates to beneficial isothiocyanates.17 Conclusion While consuming plenty of fruits and vegetables is always a good health habit, new evidence reveals that the green leafy vegetable watercress may be particularly beneficial. This lesser-known member of the broccoli family provides a rich source of isothiocyanates, remarkable compounds that scientists now believe may help fight a wide range of cancers. New evidence shows that watercress consumption protects delicate DNA against damage that could trigger cancer, while increasing levels of protective antioxidants in the blood. Watercress provides a plentiful amount of lutein and zeaxanthin, carotenoids that are essential for macular (eye) and cardiovascular health, as well as essential vitamins A, C, and K. Try adding some of this versatile vegetable to your salads and meals today. If you have any questions about the scientific content of this article, please call a Life Extension Health Advisor at 1-800-226-2370. Nutritional Content of Watercress In addition to its beneficial content of cancer-fighting compounds, watercress is an excellent source of vitamins A, C, and K, lutein, and zeaxanthin. One cup of raw watercress (34 grams) contains:8 Calories 4 Total Carbohydrates 0 g Dietary Fiber 0 g Sugars 0 g Protein 1 g Total Fat 0 g Nutrients Percent of Daily Value Vitamin A 1598 IU 32% Beta-carotene 959 mcg N/A Lutein and zeaxanthin 1961 mcg N/A Vitamin C 14.6 mg 24% Vitamin E 0.3 mg 2% Vitamin K 85 mcg 106% Folate 3.1 mcg 1% Calcium 40.8 mg 4% Magnesium 7.1 mg 2% Phosphorus 20.4 mg 2% Potassium 112 mg 3% Sodium 13.9 mg 1% Manganese 0.1 mg 4% References 1. Available at: http://www.wcrf-uk.org/cancer_prevention/index.lasso. Accessed August 2, 2007. 2. Gill CI, Haldar S, Boyd LA, et al. Watercress supplementation in diet reduces lymphocyte DNA damage and alters blood antioxidant status in healthy adults. Am J Clin Nutr. 2007 Feb;85(2):504-10. 3. Pledgie-Tracy A, Sobolewski MD, Davidson NE. Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines. Mol Cancer Ther. 2007 Mar;6(3):1013-21. 4. Higdon JV, Delage B, Williams DE, Dashwood RH. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Pharmacol Res. 2007 Mar;55(3):224-36. 5. Fowke JH. Head and neck cancer: a case for inhibition by isothiocyanates and indoles from cruciferous vegetables. Eur J Cancer Prev. 2007 Aug;16(4):348-56. 6. Hu J, Straub J, Xiao D, et al. Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1. Cancer Res. 2007 Apr 15;67(8):3569-73. 7. Juge N, Mithen RF, Traka M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci. 2007 May;64(9):1105-27. 8. Available at http://www.nutritiondata.com/facts-C00001-01c20hq.html. Accessed July 13, 2007. 9. Available at http:/www.watercress.co.uk/did/. Accessed July 5, 2007. 10. Palaniswamy UR, McAvoy RJ, Bible BB, Stuart JD. Ontogenic variations of ascorbic acid and phenethyl isothiocyanate concentrations in watercress (Nasturtium officinale R.Br.) leaves. J Agric Food Chem. 2003 Aug 27;51(18):5504-9. 11. Chiao JW, Wu H, Ramaswamy G, et al. Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest. Carcinogenesis. 2004 Aug;25(8):1403-8. 12. Boyd LA, McCann MJ, Hashim Y, et al. Assessment of the anti-genotoxic, anti-proliferative, and anti-metastatic potential of crude watercress extract in human colon cancer cells. Nutr Cancer. 2006;55(2):232-41. 13. Rose P, Huang Q, Ong CN, Whiteman M. Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicol Appl Pharmacol. 2005 Dec 1;209(2):105-13. 14. Rose P, Won YK, Ong CN, Whiteman M. Beta-phenylethyl and 8-methylsulphinyloctyl isothiocyanates, constituents of watercress, suppress LPS induced production of nitric oxide and prostaglandin E2 in RAW 264.7 macrophages. Nitric Oxide. 2005 Jun;12(4):237-43. 15. Coleman H, Chew E. Nutritional supplementation in age-related macular degeneration. Curr Opin Ophthalmol. 2007 May;18(3):220-3. 16. Ribaya-Mercado JD, Blumberg JB. Lutein and zeaxanthin and their potential roles in disease prevention. J Am Coll Nutr. 2004 Dec;23(6 Suppl):567S-87S. 17. Getahun SM, Chung FL. Conversion of glucosinolates to isothiocyanates in humans after ingestion of cooked watercress. Cancer Epidemiol Biomarkers Prev. 1999 May;8(5):447-51.


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New Scientist
New Scientist cover, 6 February 2010
Editor | Sumit Paul-Choudhury |
Categories | Science |
Frequency | weekly |
Total circulation (June 2013) |
30,698[1] |
First issue | 22 November 1956 |
Company | Reed Business Information Ltd |
Country | United Kingdom |
Language | English |
Website | www.newscientist.com |
New Scientist is a weekly non-peer-reviewed English-language international science magazine,[2] founded in 1956. Since 1996 it has also run a website.
Sold in retail outlets and also on subscription, the magazine covers current developments, news, reviews and commentary from the scientific community. It also prints speculative articles, ranging from the technical to the philosophical. There is a readers' letters section which discusses recent articles, and discussions also take place on the website.
Readers also contribute observations on examples of pseudoscience to Feedback, and questions and answers on scientific and technical topics to Last Word; extracts from the latter have been compiled into several books.
New Scientist is based in London, England, and publishes editions in the UK, the United States, and Australia. Sumit Paul-Choudhury became editor in 2011,[3] following Roger Highfield's move to the National Museum of Science and Industry in London.[4]
The magazine was founded in 1956.
The British science magazine Science Journal, published 1965–71, was merged with New Scientist to form New Scientist and Science Journal.[5]
Originally, the cover had a text list of articles rather than a picture.[citation needed] Pages were numbered sequentially for an entire volume of many issues, as is the norm for academic journals (i.e., so that the first page of a March issue could be 651 instead of 1); later each issue's pages were numbered separately. Colour was not used except for blocks of colour on the cover. In 1964 there was a regular "Science in British Industry" section with several items.[6] An article published on their tenth anniversary provides some anecdotes on the founding of the magazine.[7]
In 1970, the company Albert E. Reed acquired New Scientist when it merged with IPC Magazines, retaining the magazine when it sold most of its consumer magazines in a management buyout to what is now IPC Media.
The Grimbledon Down comic strip appeared from 1970 to 1994. Ariadne, which later moved to Nature, commented every week on the lighter side of science and technology and the plausible but impractical humorous inventions of (fictitious) inventor Daedalus, often developed by the (fictitious) DREADCO corporation.[8]
As of the first half of 2013, the UK circulation averaged 125,172, a 4.3% reduction on the previous year's figure, but a considerably smaller reduction than many other mainstream magazines of similar or greater circulation.[9]
New Scientist runs advertisements for jobs and academic opportunities in the field of science. In the early days[when?] they were in a "Classified Advertisements" section with subsections "Official Appointments", "Appointments and Situations Vacant", and "Travel", with a list of coach holidays and prices. The general classified section was dropped in favour of what has become "NewScientist Jobs".
Other advertising (particularly but not exclusively of interest to scientists and technologists) is carried in the magazine.
The New Scientist website has blogs and limited news articles and is available to anybody; users with free-of-charge registration have limited access to new content and can receive emailed New Scientist newsletters. Subscribers to the print edition have full access to all articles and the archive of past content that has so far been digitised. As of 2012[update] a Web 30-day access pass was available, at different prices in different countries (e.g., US$19.95 in the United States).[10] The website also has special reports on many topics.
The magazine had a weekly podcast, SciPod, which was discontinued in October 2007.
In late 2004 NewScientist.com added a subdomain, "nomoresocks" (No More Socks), where visitors could search for, rate, and discuss innovative gifts. Use of the site had dropped considerably by June 2005, and it was since discontinued.
From mid-2006 some New Scientist content was made available to users of Newsvine, a community-driven social news website.
From mid-December 2009 to March 2010 non-subscribers could read up to seven articles per month.
In November 2009 New Scientist started The S Word, a blog providing a forum for the discussion of "The science of politics – and vice versa". It was so named because "Despite the central role that science plays in our world, politicians often seem reluctant to engage with it", with the aim of the blog being to help "persuade politicians that 'the s word' belongs at the heart of political debate".[11]
The technology, environment and space sites were discontinued in 2008, with the content being integrated into the main NewScientist.com site. The site also includes a blog on a range of topics from inventions to "short sharp" science.
Over the years New Scientist has published several series of books derived from its content. Most recently it has compiled seven books of selected questions and answers from the Last Word section of the magazine and the Last Word website.
- 1998. The Last Word. ISBN 978-0-19-286199-3
- 2000. The Last Word 2. ISBN 978-0-19-286204-4
- 2005. Does Anything Eat Wasps? And 101 Other Questions. ISBN 978-1-86197-973-5
- 2006. Why Don't Penguins' Feet Freeze? And 114 Other Questions. ISBN 978-1-86197-876-9
Why Don't Penguins Feet Freeze? is largely a repackaging of selected material from the first two books, following the unexpected mass-market success of Does Anything Eat Wasps?
- 2007. How to Fossilise Your Hamster: And Other Amazing Experiments For The Armchair Scientist. ISBN 978-1-84668-044-1
- 2008. Do Polar Bears Get Lonely?: And 101 Other Intriguing Science Questions. ISBN 978-1-84668-130-1
- 2009. How to Make a Tornado: The Strange and Wonderful Things That Happen When Scientists Break Free. ISBN 978-1846682872
- 2010. Why Can't Elephants Jump?: And 113 More Science Questions Answered. ISBN 978-1-84668-398-5
- 2011. Why Are Orangutans Orange?: Science Questions In Picture - With Fascinating Answers. ISBN 978-1-84668-507-1
- 2012. Will We Ever Speak Dolphin?: And 130 Other Science Questions Answered. ISBN 978-1-78125-026-6
In 2012 Arc, "a new digital quarterly from the makers of New Scientist, exploring the future through the world of science fiction" and fact was launched.[12] It is available in several ebook formats, and a "collectable print edition".
Also in 2012 the magazine launched a dating service, NewScientistConnect, operated by The Dating Lab.
Appearances in popular culture[edit]
- During the introductory sequence of the 1965 film The Ipcress File, a character is shown reading the magazine.[13]
- In the first episode of the 2012 British sitcom Friday Night Dinner, a character is shown to obsessively collect the magazine.[14]
Greg Egan's criticism of the EmDrive article[edit]
In September 2006, New Scientist was criticised by science fiction writer Greg Egan, who wrote that "a sensationalist bent and a lack of basic knowledge by its writers" was making the magazine's coverage sufficiently unreliable "to constitute a real threat to the public understanding of science". In particular, Egan found himself "gobsmacked by the level of scientific illiteracy" in the magazine's coverage of Roger Shawyer's "electromagnetic drive", where New Scientist allowed the publication of "meaningless double-talk" designed to bypass a fatal objection to Shawyer's proposed space drive, namely that it violates the law of conservation of momentum. Egan urged others to write to New Scientist and pressure the magazine to raise its standards, instead of "squandering the opportunity that the magazine's circulation and prestige provides".[15]
The editor of New Scientist, then Jeremy Webb, replied defending the article, saying that it is "an ideas magazine—that means writing about hypotheses as well as theories".[16]
"Darwin was wrong" cover[edit]
In January 2009, New Scientist ran a cover with the title "Darwin was wrong". The actual story stated that specific details of Darwin's evolution theory had been shown incorrectly, mainly the shape of phylogenetic trees of interrelated species, which should be represented as web instead of tree.[17] Some evolutionary biologists who actively oppose the intelligent design movement thought the cover was both sensationalist and damaging to the scientific community.[17][18] Jerry Coyne, author of the book Why Evolution Is True, called for a boycott of the magazine, which was supported by evolutionary biologists Richard Dawkins and P.Z. Myers.[17]
See also[edit]
- ^ "Mag ABCs: Full circulation round-up for the first half of 2013". Press Gazette. 15 August 2013. Retrieved 7 December 2013.
- ^ Krauss, Lawrence. "Commentary: Editors must be our gatekeepers". New Scientist, no. 2671, 27 August 2008, p. 46.
- ^ "Who's Who at New Scientist". New Scientist. Retrieved 2 December 2011.
- ^ "About Roger Highfield". RogerHighfield.com. Retrieved 2 December 2011.
- ^ National Library of Australia Bib ID 2298705
- ^ New Scientist, vol. 21 No. 382, 12 March 1964
- ^ Calder, Nigel (24 November 1966). "How New Scientist got started". New Scientist.
- ^ New Scientist for 19 January 1978
- ^ "PressGazette circulation figures". Retrieved 4 Oct 2013.
- ^ Web 30-day access pass
- ^ "Welcome to the S Word!". New Scientist. 24 November 2009.
- ^ Arc URL, redirects to http://www.newscientist.com/arc
- ^ New Scientist (2013). "New Scientist - 11 February 1988 (on Google Books)". books.google.co.uk. Retrieved 7 January 2013.
- ^ Friday Night Dinner - Reviews and Press Articles - British Comedy Guide
- ^ John C. Baez A Plea to Save New Scientist
- ^ Emdrive on trial
- ^ a b c Pharyngula: New Scientist flips the bird at scientists, again
- ^ The New Scientist has no shame–again! Why Evolution Is True blog, 21 March 2009.
External links[edit]


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Summer > Summer Events
Canazei Night Event Summer Edition
23 August 2012 h: 21:00
On Thursday 23st August Canazei will suddenly turn into a magical winter village: Strèda Roma and Piaz G. Marconi will become white thanks to some soft snow and it will be possible to enjoy the Ski School Canazei Marmolada ski instructors' choreograpy followed by a suggestive torchlight procession.
From 9.00 p.m. will start the alpine skiing, snowboarding, cross-country skiing and freestyle show. The snow professionists will jump and ski making you living the winter fantastic atmosphere in Val di Fassa, the unquestioned winter capital.
See all news


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Avatar Nations Series - Water Tribe
by Miss-meza
Art Print
Collect your choice of gallery quality Giclée, or fine art prints custom trimmed by hand in a variety of sizes with a white border for framing.
Represent your favorite Avatar Nation with pride! Now available as a print, Ipod/Iphone case, and t-shirt/hoodie!
- 8Promote


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This Audio Cable enables you to connect your HTC device to your compatible Hi-Fi or speaker system with a 3.5mm port. This cable is made of a rugged connector to extend the functionality of your device and allow you to listen to your favorite music any time.
Product Type | Audio cable |
Software included | No |
Cables included | Not Available |
Brand | HTC |
Manufacturer's Part Number | 73H00305-00M |
Service / Support | 1 year warranty |
Color | Not Available |
Category | Not Available |
Dimension | Not Available |
Weight | Not Available |
Size | Not Available |
display_name | Not Available |
* Information on this web site may contain technical inaccuracies or typographical errors. Information may be changed or updated without notice. LetsTalk.com may also make improvements and/or changes in the products and/or programs described in this information at any time without notice.


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This is a high quality Magnavox SW200/17 Replacement Subwoofer. It features 6" Size.


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< Return To Hearing
The Honorable Patrick Leahy
United States Senator
Opening Statement Of Senator Patrick Leahy (D-Vt.), Today, I hope the Committee will favorably consider the bipartisan Fighting Fraud to Protect Taxpayers Act that Senator Grassley and I introduced with Senators Klobuchar and Coons. Combating fraud is a vital issue on which we have a long track record of working together, with great success. This legislation will build on our success over the last couple of years of passing bipartisan legislation to help combat fraud. In these difficult budget and economic times, cracking down on the fraud is more important than ever. I urge all Senators from both parties to support this crucial legislation. In the last Congress, one of the first major bills this Committee considered, and one of the first bills President Obama signed into law, was the Leahy-Grassley Fraud Enforcement and Recovery Act. That bill gave fraud investigators and prosecutors additional tools and resources to hold accountable those who commit fraud. That law has already resulted in significant success, as we heard at our hearing earlier this year. Over the past two years, we have learned much more about financial fraud, mortgage fraud, government contracting fraud, health care fraud, and oil and gas fraud. The bill we bring to the Committee today reflects the ongoing need to invest in enforcement to better protect against these insidious types of fraud. In the last fiscal year alone, the Department of Justice recovered well over $6 billion through fines, penalties, and recoveries from fraud cases. These recoveries demonstrate that focused investment in fraud enforcement pays for itself many times over. The centerpiece provision of the Fighting Fraud to Protect Taxpayers Act capitalizes on this rate of return by ensuring that a small percentage of money recovered by the Government through fines and penalties is reinvested in the investigation and prosecution of fraud cases. That means more fraud enforcement, more recoveries for the Government, and more savings to taxpayers, all without spending new taxpayer money. The renewed focus on fraud enforcement we have seen from Congress and this administration have yielded significant results. We should continue to strengthen the tools that law enforcement needs to root out fraud. Everyday, taxpaying Americans deserve to know that their Government is doing all it can prevent fraud and hold those who commit fraud accountable for their crimes. Fighting fraud and protecting taxpayer dollars are issues Democrats and Republicans have long worked together to address. I thank Senator Grassley for his commitment to these issues, and ask the Committee to join us in supporting this important bill. |


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Whether in the hospital, in the emergency room or in a clinic, all children have basic needs that must be met, and these needs may be magnified by illness, injury or loss of the familiar routines of life.
To help support their special psychosocial and educational needs, the UMass Memorial Children's Medical Center has certified child life specialists to help pediatric patients and their families cope with a potentially stressful health care experience.
The goals of the Child Life Program include:


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Small/large tools, house odds/ends, clothing/accessories, multiple family sale. More info Email a friend |
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"LIVING COLLECTORS" MASSIVE ESTATE SALE SAT & SUN 8-4 1026 E. Holland, Old Fig Antique & vintage furn, decor & collectibles: oak telephone booth; oak curved glass curio & buffet, DR chairs; Duncan Phyfe tbl; antique wicker; garden d cor; vintage stone fountain... More info Email a friend |
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ESTATE DOWN SIZING SALE Sat March 16 9am 7353 N. Bennedict N/Herndon off Marks W/VanNess Lakes. Furn, including sofa, loveseat, hide-a-bed, occassional tables, unusual entry way cabinet, chest, patio items, framed art & photographs, refrig, washer/dryer... More info Email a friend |
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3 Family Yard Sale- 5258 North Maroa. Sat 3/15 & Sun 3/16 from 8am-4pm. Appliances, furniture & clothing. More info Email a friend |


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Some information is missing or invalid below.
This rug rounds off your contemporary décor. The intricate medallion pattern offers a rich representation of modern style, instantly updating your home. Plus, you'll simply adore the splash of fresh color this stunning rug delivers. In taupe/multi.
- Scroll and floral accents add elegant allure.
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- Details:
- Nonslip latex backing
- Olefin
- Spot clean
- Attention: All rug sizes are approximate and should measure within 2-6 inches of stated size. Pattern may also vary slightly.


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USD $5.59I Just love it!<3 Soft,and easy to handle,Lovely red colour<3
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