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PROS: Good highlight option for not making pores look so big like highlight powders and some creams do. Beautiful highlight. It's a gold and pink opaque combination (I know...sounds crazy.) Even though it's has gold tone in it, it looked great on my N15 skin that tends to lean to the NC side. Looked even better than High Beam did because it's more subtle (not as frosty.)
CONS: Container would not allow you to get at the remainder of the product. Can get goopy at top of jar where the lid screws on.
ALTERNATES: Laura Mercier's Secret Brightening Pen or some name like that is great for subtle shimmer.
1 out of 1 people found this review helpful. Did you? Yes No
More reviews by summertimecrime
Moon Beam is a gold tinged apricot colour. It can be used as a highlight on the face or body, mixed with your foundation for a nice glow, used as a brow highlight, over lipstick, etc. I found that the packaging didn't work for me very well, as it is sold in a nail polish containedr with nail polish brush. It's better to get a little bit on your finger and use a makeup brush suited for whatever you're going to do with it! In the jar, it has a subtle shimmer, but on the skin, it all but disappears and leaves a very faint shine in its place. The product is too thin and almost "runny", so you feel like you need to use a lot to get any colour. As for colour payoff-there is literally none to speak of! Is it worth the price? I don't think so, as there are far better liquid highlights out there. I wouldn't buy this again, it's mediocre highlight for a high price.
2 out of 2 people found this review helpful. Did you? Yes No
This product doesn't show up when applied under foundation, whereas when applied on top it smudges it. Def not worth the price tag.
i like this product to eyelight my brow bone, makes my eyebrows look more defined and groomed, i dont know if i would re purchase though, its a bit expensive and other cheaper products can do the same job
there are so many things wrong with this product. if you have oily skin, the shimmer in this just makes it look worse. if you "pat" it over the top of your foundation, which is the suggested use, it just moves your foundation around and all your hardwork is undone. you can mix it into your foundation for a "dewy" look, but i would only suggest this for very dark skin with pink undertones, as it is a pinkish gold, and not if you are oily. the applicator is like a nail polish bottle and the product gets gooey and gross all around it. the top breaks off really easily. i worked for benefit for a year and i had to try to sell this to people and i felt horrible every time someone bought it, because i knew it was one of the worse things they make!! there are much better highlighters out there, don't waste your money on this dud.
I have high beam, but moon beam is more natural looking on my skin. It has a slight pink sheen to it, but nothing dramatic at all. It makes me look more awake & pretty without looking obviously made up. High beam is more dramatic and obvious even if you apply a little bit, so i love Moon Beam on me. It is really expensive, but ive had my bottle for over a year & i have a lot left
I have never had a product solely for highlighting before, so i decided to purchase Moon Beam. I had swatched it about 10 times in Ulta but could never convince myself to spend $24 on a highlighter. But I finally made the plunge and i'm glad i did. I will mostly use this as a inner corner and brow bone highlight. But I have also used it on the cheekbone if i want to add a little bit of glow. I like this product and although it is subtle, it does exactly what i wanted it to without making me look like a 8 year old who caked on body glitter from Claires
its really subtle. it does illuminate my face but nothing too dramatic. I hate mixing it with my tinted moisturizer because it doesnt set well and makes my pores look huge.it looks really nice when used on my body i wouldnt buy this again.
More reviews by graceholliwell
Better than High Beam in that it is less harsh and less obvious that you are wearing it, but it has the same problems with texture and it dries too fast often leaving streaks.
Not a make up bag essential, but I'd probably buy it again.
This product didn't deliver on the "glowing" results I had hoped for. I was a little aprehensive about buying it as it seemed to be a little pricey, but I did it anyway and couldn't wait to try it. Well, I tried it on a number of different areas on my face, on top of my makeup, underneath my makeup, on bare skin with no make-up at all and while I noticed a slight shimmer/glow straight away, within an hour or so, it had gone. I don't really know who I can recommend this product to as I'm not sure how it manages to make some women glow and others don't see it at all.
All I can recommend is that you try before you buy. I didn't and I do regret it because it's just sat in my make-up bag not getting used.


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The Whitestown Pee Wee Pop Warner football team just finished up their regular season undefeated! Today they played the Norwich Cyclones and won 27-6! Next weekend the team starts the playoffs!
Whitestown Pee Wee Pop Warner Football
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subset: commoncrawl


text:
Teuchos Package Browser (Single Doxygen Collection) Version of the Day
Templated BLAS wrapper. More...
#include <Teuchos_BLAS.hpp>
Private Types | |
typedef Teuchos::ScalarTraits < ScalarType >::magnitudeType | MagnitudeType |
Constructor/Destructor. | |
BLAS (void) | |
Default constructor. | |
BLAS (const BLAS< OrdinalType, ScalarType > &) | |
Copy constructor. | |
virtual | ~BLAS (void) |
Destructor. |
Templated BLAS wrapper.
The Teuchos::BLAS class provides functionality similar to the BLAS (Basic Linear Algebra Subprograms). The BLAS provide portable, high- performance implementations of kernels such as dense vector sums, inner products, and norms (the BLAS 1 routines), dense matrix-vector multiplication and triangular solve (the BLAS 2 routines), and dense matrix-matrix multiplication and triangular solve with multiple right-hand sides (the BLAS 3 routines).
The standard BLAS interface is Fortran-specific. Unfortunately, the interface between C++ and Fortran is not standard across all computer platforms. The Teuchos::BLAS class provides C++ bindings for the BLAS kernels in order to insulate the rest of Petra from the details of C++ to Fortran translation.
In addition to giving access to the standard BLAS functionality, Teuchos::BLAS also provides a generic fall-back implementation for any ScalarType class that defines the +, - * and / operators.
Teuchos::BLAS only operates within a single shared-memory space, just like the BLAS. It does not attempt to implement distributed-memory parallel matrix operations.
Definition at line 227 of file Teuchos_BLAS.hpp.
typedef Teuchos::ScalarTraits<ScalarType>::magnitudeType Teuchos::BLAS< OrdinalType, ScalarType >::MagnitudeType [private] |
Reimplemented from Teuchos::DefaultBLASImpl< OrdinalType, ScalarType >.
Reimplemented in Teuchos::SerialBandDenseSolver< OrdinalType, ScalarType >, Teuchos::SerialDenseSolver< OrdinalType, ScalarType >, Teuchos::SerialQRDenseSolver< OrdinalType, ScalarType >, and Teuchos::SerialSpdDenseSolver< OrdinalType, ScalarType >.
Definition at line 230 of file Teuchos_BLAS.hpp.
Teuchos::BLAS< OrdinalType, ScalarType >::BLAS | ( | void | ) | [inline] |
Default constructor.
Definition at line 237 of file Teuchos_BLAS.hpp.
Teuchos::BLAS< OrdinalType, ScalarType >::BLAS | ( | const BLAS< OrdinalType, ScalarType > & | ) | [inline] |
Copy constructor.
Definition at line 240 of file Teuchos_BLAS.hpp.
virtual Teuchos::BLAS< OrdinalType, ScalarType >::~BLAS | ( | void | ) | [inline, virtual] |
Definition at line 243 of file Teuchos_BLAS.hpp.


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Thursday, March 13, 2008
If the font is too small you can enlarge it with Cntrl+.
From the standpoint of this site being about sharing process I find the current state of the China investment theme to be particularly difficult right here. As disclosed previously I had close to across the board exposure to China with Sinopec (SNP), charted in red, that I first bought in 2004. I sold the last of it last May over concern that the run would soon come to an end. I did not use a stop order because at the time the day to day movement did not, IMO, lend itself to stop orders.
The sale was good in that older clients made 2 1/2-3 times their money, the sale was so-so except I was a few months early, the sale was bad because while I sold at $103 it peaked out at $178 (point there being there are many ways to look at a sale). Sinopec closed yesterday at $96.26.
What makes it difficult is that many things related to China are down a lot; the Shanghai Composite, charted in blue, is down about 30% from its peak in October which is a lot but there doesn't seem to be any recognition of the decline and I can't recall any what's wrong with China articles or TV segments. There was virtual panic (slight exaggeration) when the US market was down 5%, China is down 30% and very few, if any, people seem to care.
Down 30% is not the worst place to initiate a position because often people start to give up at about that level which is why 30% is about the average size bear market decline in the US. But if China is down 30% and no one is even miffed, holding off seems right but that is what makes this a tough call.
Just so no one gets confused I am talking about the price of stocks not the story on the ground in China. I have been convinced for years now that China is a huge story and could easily supplant the US in being the globe's big Kahuna but none of that makes it immune from bear markets. The stock I want buy is not down anywhere near the 46% that SNP is down, but it is down noticeably and like I was saying with financials the other day I feel good about where the price will be 36 months from now but three months is tougher to see.
This hopefully shows that it is ok to not know. No one can know everything, there cannot be perpetual clarity with everything. I think I am reasonably well in touch with the theme (stocks going down, CPI going up, GDP going down, yuan going up, the magnitude of importance of the Olympics) but for now I don't feel like I have solved it just yet. This has happened with other things in the past and will happen in the future, it is normal.
5 comments:
- Anonymous said...
Roger, as a follow on to yesterday's discussion, would you use the 200 dma to time your entry/exit into the Chinese market (or any other market for that matter?) Thanks.
- Roger Nusbaum said...
the short answer is obviously yes and of course the Shanghai Comp is below its 200 DMA.
I view the 200 DMA as a tell for how to position the entire portfolio (more defensive/less defensive as a shortened version) not each of the components but other people (Tom Lydon as one example) seem to use the 200 DMA for every position. I think that would cause more trading than I want plus I am more concerned with the bottom line number not each of the components--hence my preference for the double short fund. - 7:33 AM
- Anonymous said...
There's a good 2 minute video on China at FT.com. Key points ...
The credit crisis has kept China in the background somewhat.
China has gone from a cause for hope to a cause for concern.
Shanghai has fallen further from its peak than the Nasdaq in the equivalent time period. - 9:04 AM
- Frank Rizzo said...
Re. China, I'd recommend anyone up for a bit of fun to try the China (or HK, depending on how you look at it) UltraShort, FXP. It whipsaws like crazy (down 20% Tuesday, now up 10-15% from there), and a good (?) way to capture China's cratering. I'm holding on to it for the next few months, buying the dips as I go.
- Anonymous said...
I thought I would ask those here if they own Altria and will sell before the spin off of PMI. Seems like a good idea to me.


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Dustin Brown is a worthless piece of shit, and people are finally starting to figure it out. Kings @ Ducks.
John Scott is clearly a physical player but is he the dirty-hitting, intent-to-injure, goon that he's being painted as lately?
The gang talks about goons before tonight's Ducks @ Wild matchup.
"Goon" is a new movie about a hockey brawler, played by Seann William Scott. There is a decided gay angle, with Scott having a younger brother who is gay. Scott evens gets goaded by his friend into...
At it's core, Goon is a movie with a good and sweet heart. A very raunchy and disgustingly bloody heart, but a good heart nonetheless.
A rare treat for hockey-centric cinephiles, "Goon" will be released in US theaters on Friday, March 30th.
A review of the hockey movie "Goon," which doesn't meet the "Slap Shot" standard but comes much closer than most hockey movies.
Jeremy Yablonski took his act to Russia's KHL, but never learned his lesson. Now that he's banned from the Russian league, the AHL should follow suit.
Meetups, Beatups and Bits #isles
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In this morning's Web roundup, Xpert Financial has retrenched and its founder is raising money for a new company, CapRally. Ambit Biosciences has raised $25 million towards a $50 million round to help it advance a leukemia drug through Phase III clinical trials. Also, the verdict is out on online legal services.
Produced by the editors of Dow Jones VentureWire, Venture Capital Dispatch tracks the fast-moving developments at the intersection of high-tech innovation and venture capital finance. Featuring the VentureWire reporting team in the Silicon Valley, New York, Boston and Shanghai tech centers, Venture Capital Dispatch provides insight into the newest start-ups and latest trends in venture capital investing. Write us at email@example.com. For more information on Dow Jones products covering venture capital and other financial markets, go to www.fis.dowjones.com.


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Home | RSS Feeds |
Funny Pictures | Funny Videos |
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themodyourgod (04/11/2013) [-]
Whovian here who only started with DW ******* , but has heard nothing but good things about Tom Baker's portrayal of the Doctor. Can someone suggest for me a few of his better episodes/story arcs that I could watch to get an understanding of his character? Will reward with random pics


text:
Type | Feature Film |
MPAA Rating | NR |
Runtime | 1hr 35mins. |
Genres | Drama, Crime, Thriller, Short Film |
Status | Released |
US Release Date | N/A |
Colin Farrell's new fantasy epic 'Winter's Tale' has a lot of interesting ideas, but doesn't deliver on most of them.
Finally, an adaptation British fans can breathe easy over.
Courtney Love appears to be deadly serious about her plans to mend fractured friendships in 2014 - a new photo has sparked talk of an unlikely Hole reunion.
Producers of Paul Walker's latest film Hours have decided to proceed with the release as planned, despite the actor's death.
The team's jet is downed as they fight a mysterious apparition.
Sir Patrick Stewart's wedding wasn't inspired by 'Star Trek,' but what would it be like if it was?
Veteran British actor Bill Pertwee has died at the age of 86.
Kyle has her annual shindig, and Kim unveils her new nose.
Someone got a GIF of Jeremy's shirt-rip, right?
Are you shocked? By death?
Name | Credit | Credited as |
Marilyn Boyle | Actor | Supervisor |
Al Ramrus | Screenwriter |


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SGT David Wimberg, 24, was a member of a Marine Reserve unit based [in Louisville, KY]. He was killed in Hadithah, in western Iraq on May 25, 2005.Wimberg, a 1999 graduate of Louisville Trinity High School, was a squad leader in Iraq. He and his fellow Marines were pinned down in a street after an enemy ambush, according to a citation signed by Secretary of the Navy Donald Winter.It said Wimberg left his covered position, "maneuvered through intense small-arms fire and scaled a wall" to reach the courtyard where the attackers were."Although twice driven back by high volumes of enemy fire, on his third attempt, he opened the gate and allowed his squad to enter" the courtyard. After two failed attempts to breach the front door of the house where the gunmen had holed up, "Sgt. Wimberg kicked in the door."Wimberg was then face to face with four armed insurgents, and he "engaged the enemy at close quarters, firing his M16-A4 rifle until he was shot and fell to the ground unconscious," the citation said.His actions "created the momentum needed to break the ambush. Many Marines' lives were saved as a result of Sgt. Wimberg's decisive and selfless actions," it said.Gunnery Sgt. Larry Bowman, who served with Wimberg in Iraq, described him as "an exceptional Marine and a great leader. We had great respect for him."
Buy Dale's Book!


text:
Press and Media CenterBeehive State Buzzing with ExcitementCan Lance run? Will DeBoom stay close enough on the bike? Is there enough technical riding and running to bring out the best in the Caveman? Could this be the race that makes Josiah a household name? Perhaps the Frenchman will peak at just the right time? Maybe Seth will have the magic day? Or is this the race Hugo busts out of the shadow of his mentor and becomes the champion? Thank goodness races aren't decided on paper, as the questions on "who can do what" at this year's XTERRA USA Championship are simply too difficult to answer. One thing is for certain, a pair of 40-year-old XTERRA rookies, Lance Armstrong and Tim DeBoom, ignited a firestorm of interest into what was already off-triathlon's national treasure. The other wildcard is a brand new 7+ mile Sardine Peak Trail that extends the mountain bike course to one of the Wasatch Range's most visible peaks at 7,300-feet. The 360-degree views that span from east to west are nothing short of breathtaking. Combine more than 1,000 of the world's best athletes with one of the nation's best courses, perfect weather, and a community brimming with excitement and support and you have all the right ingredients for an intense showdown at Snowbasin Resort near Ogden, Utah. Yet, intense isn't the right descriptor – fun is. "More than a decade ago I saw a picture of Steve Larsen running his bike through a creek in Richmond, Virginia and said 'wow', that looks like fun, so I applied my fitness to XTERRA and I really enjoy it," said defending USA Champ Conrad "the Caveman" Stoltz (pictured above), who is shooting for XTERRA U.S. Pro Series title No. 9 on Saturday. "I think that's the same thing that draws Lance Armstrong here. I presume he's coming here to have fun and enjoy." It's most certainly the reason Tim DeBoom is here. "Oh yeah, the fun factor, and you know it's for real when you see a guy like Conrad stick around the sport for 10 years," said the two-time Ironman World Champ who is making his XTERRA debut on Saturday. Indeed, the overwhelming majority of the men's pro field have been in the mix for years, and it may be that experience – the time put in on racing against each other and at high speeds and on this mountain – that will make all the difference. The humble and soft spoken Josiah Middaugh, a true mountain man of all season and the six-time XTERRA National Champ, is certainly hoping so. THE WOMEN'S RACE HAS DRAMA TOO On the surface it seems that this is Melanie McQuaid's race. She's won here the last three years, is in great shape, confident and determined. Lesley Paterson, however, has progression on her side. She was fourth here in Utah in 2008, third in '09, and second last year. "It suits me no doubt, lots of climbing, not too technical, and I race well at altitude," said the fiery Scottish triathlete (pictured), who is also a film producer and writer. "This is my year to win it maybe, who knows!" Perhaps, but what if a miracle happens, and the reigning XTERRA World Champ Shonny Vanlandingham is able to overcame the aches and pains associated with a torn anterior cruciate ligament in her left knee? "I tore my ACL five weeks ago, 90% off the femur," said Vanlandingham, who has a custom brace that will do its best to keep her from further injuring the knee. "I really just want to finish the race, and don't have the same expectations of winning as I did five weeks ago but I I'm an athlete, I love to compete, and I am a woman of faith. And, I do believe in miracles so it's not totally out of my mind that I could win this race. I do believe it's possible." Vanlandingham has surgery scheduled on Oct. 7, so she won't be able to race the XTERRA World Championship in Maui, but she will attend to support her fellow athletes and the sport. While those are the premier three in the women's race, the field is stacked and deep. Watch out for Kelley Cullen – a mountain biker with mountain credentials – and Sara Tarkington, who is another great climber. Emma Garrard from nearby Park City has had a great season, as has Canadians Danelle Kabush and Christine Jeffrey, who will lead them all out of the water. Everywhere you turn there is a pro contender here in Utah, and they are all wearing smiles and having fun. Only two, however, can ultimately walk away with the biggest grin – and the title of XTERRA USA Champion. Who will they be? |
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text:
(Source: insertfandomreference)
52,609 notes
06:22 AM . 25 August 2012 |
(Source: insertfandomreference)
43,323 notes
03:16 PM . 24 August 2012 |
on a scale of one to Dean, how much do you hate yourself?
Somewhere between Bruce Banner and the Doctor.
This post is so far away from okay it physically hurts
(Source: tetsuyaryoutaarchive)
114 notes
06:57 AM . 21 August 2012 |
405 notes
12:34 AM . 17 August 2012 |
always with the fisting, this one.
Not all of lifes problems can be solved with fisting, Tony
72,941 notes
11:48 PM . 31 July 2012 |
"Let him have the coat, officer."
"But Detective Lestrade, it's evid—"
"He's been through enough."
wow this isn't even remotely all right
no this isn't what i wanted why would you do that
(Source: weavile)
161 notes
07:10 PM . 28 July 2012 |
25,533 notes
03:17 PM . 24 July 2012 |
ok question if you could pee your favorite beverage would you drink it. this is an important question
(Source: dippidy)
19 notes
01:01 AM . 14 July 2012 |
(Source: bawicons)
78,281 notes
09:00 PM . 10 July 2012 |
No matter who you are, what you have been through, how terrible you have felt, regardless of where you come from, what you do, what you look like, how you behave, always know that one thing above everything else is true.
Jack Harkness would fuck you.
2 notes
09:51 PM . 20 June 2012 |
so I'm just rewatching a few Doctor Who episodes because of Captain Jack and I forgot how much I love Nine and now I regret everything
"Have a good life. Do that for me, Rose. Have a fantastic life."
just because you have two hearts Doctor doesn't mean you can rip out mine


text:
Brandon Stokley knew he had more in him.
Since his last stint with the Broncos, he spent time with the Seattle Seahawks in 2010 and New York Giants in 2011, playing in just two games last season before suffering an injury.
But the 14th-year veteran didn't contemplate retirement.
"I wasn't really ready to be done — I still feel like I can play," he said. "For me, it was just all about trying to get that opportunity somewhere."
The Broncos provided that opportunity, and it's one Stokley won't take for granted.
Not only does he get a chance to prove he still has it, but his return to the Broncos means a reunion with a former teammate — quarterback Peyton Manning.
"I didn't ever think I would have another chance to play with him," Stokley said. "When you're there (in Indianapolis), I was there with him for four years. I don't want to say you kind of take him for granted, but then you move on and you kind of realize what you had. You kind of always hope that you'll get that chance again. For me, it's been great. To me, I think he's the best to ever play the position. So to have another chance to play with somebody like that is pretty special."
Stokley and Manning were together in Indianapolis from 2003 to 2006 before the receiver headed to Denver in 2007.
Stokley said he doesn't see much difference in the way Manning is delivering the ball now than when he was in Indianapolis — something that he believes will benefit everyone on the team, but Eric Decker and Demaryius Thomas in particular.
"The last time I saw them, they were both rookies, young pups," Stokley said. "Now you can definitely tell that they've both grown up and have taken on the leadership role. It is their receiver group, it's their chance to do something special. They're playing with a guy that can get them the ball. I've seen him help a lot of people's careers. I think he can do that for both of those guys."
Stokley said he is healthy and feels "100 percent." Now he's focused on being a Bronco again.
"It's great," he said. "I'm having a blast, just enjoying the moment. I'm glad to have a chance to play football again."
-Gray Caldwell
Tags: Brandon Stokley


text:
Cradle to Cradle CertifiedCM
gDiapers are the only diaper inserts to be certified Cradle to Cradle. It means that everything that goes into a gDiapers disposable insert will be re-absorbed by the planet in a neutral or positive way when home composted (wet ones only).
Compostable diapers.
Turn waste into a resource with compostable diapers. Wet-only disposable inserts can be home composted. From diaper to garden in the blink of an eye.
rip, swish, flush.
Flushable diapers? gDiapers disposable inserts are flushable in North America. Put poop where it belongs, down the toilet, not the garbage can. It's as simple as rip, swish, flush. Just follow the easy directions.


text:
Running Form
Recent Articles
How Your Thoughts Affect Your Running EfficiencyPositive feedback produces improvements in running economy. | Heel Landing Beats Midfoot In Half-Marathon StudyFirst research of its kind investigates running economy of 1:10 half marathoners. |
Are Bouncy Running Strides More Economical?A new study of "stride angle" produces unexpected results. | The Pros and Cons of Stride VariabilityHaving a consistent stride may help keep you injury-free. |
Faster Stride Rate Might Help With Knee PainImpact forces decrease 14% with 10% increase in turnover. | |
How Different Foot Strikes Affect Different Body PartsRunners with knee, Achilles injuries might be best candidates for switching. | Study: Rearfoot, Forefoot Strike Equally EfficientStudy's design makes it best yet to compare forefoot and rearfoot running. |
Study: Few Differences Between Heel, Non-Heel StrikersIn large Army study, similar performances and injury rates. | New Runners Don't Self-Select Best Stride RateIn study, increasing stride frequency leads to more economical running. |
Study: Running Surface May Determine Type of Foot StrikeRunners seem to select a rearfoot strike for soft surfaces, forefoot for hard. | How Type of Shoe Changes Young Runners' FormStudy finds foot strike changes instantaneously and significantly based on type of shoe. |
Footstrike And Its Possible Effect On Lower Back PainDoes a forefoot running style reduce lumbar lordosis and back pain? | Find Your Chi (Running)Effortless running takes some effort—and other lessons learned by a chronically injured runner at an alternative running school. |
New Study Reaches Different Conclusion On Kenyan Foot StrikesThe question: What's the "natural" way to run? | |
Simple Truths About 180 Strides/MinuteIt's not a magic number; you have to know your goals. | In Study, Almost All New Runners Heel StrikeMore than 890 of 903 novice runners landed heel first. |
How Can I Open My Stride Length?Running on a treadmill affects stride length differently than running outdoors. | Changes to Stride, Surface and Form to Avoid InjurySimple adjustments to your routes, form, and mileage can help sidestep injury. |


text: I have two male dogs in the house these days. It's nothing new for me to own two dogs at the same time. I've had two dogs with me for most of my adult life. But usually I've had a female and a male. The dual male combo hasn't been anything of an issue until just recently.


text:
Articles firstname.lastname@example.com firstname.lastname@example.com |
O.O.D.E. ORTHODOX OUTLET for DOGMATIC ENQUIRIES. Search OODE website(through Google)Discover Orthodox Christianity! http://www.oodegr.com/english/index.htm |
The copying and re-publishing of articles composed by O.O.D.E. is permitted, provided that their contents are not altered, and the source of those articles is clearly mentioned.
File published in English on: 3-8-2005.
Last update: 14-3-2006.


text:
Self-Service Banner (SSB) Students, employees, and prospective students use Self-Service Banner (SSB) to check the status of financial aid applications and awards, view personal information with human resources, see pay stubs, interact with university purchasing systems, register for new student orientations, and more.
Accessibility for Self-Service Banner (SSB) Users with accessibility needs can access Self-Service Banner here.
Travel and Expense Management Users can manage travel and expense activity such as travel funds, authorize expenditures, reimbursements, approvals, and generate reports to request university vehicles.
SciQuest An online catalog and ordering system. Users can perform Direct Pay Requests (payment request vouchers), Standing Orders, and Equipment Requests (B24).
Argos View, save and print reports from Argos, our reporting tool for Banner.*Users must have Windows browser for the required add-on.
Blackboard The address for Blackboard has changed to http://blackboard.bsu.edu. Please update your bookmarks.


text:
Got a question? Something on your mind? Talk to your community, directly.
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Zorbie Hot Tub Water Bobble
Product Description
The Zorbie Hot Tub Water Bobble has a unique ion exchange mechanism which is designed to absorb contaminants and to reduce foaming in your hot tub. The Water Bobble lasts 30 to 90 days, depending on bather load. You should change your Zorbie Water Bobble when it settles low in the water.
For the more technically minded......
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CNET UK > Reviews > Mobile Phones and Apps > Mobile Phones
Samsung Wave GT-S8500 review
With hardware as slick as a greased otter, but software that's rough around the edges, the Wave is Samsung's latest effort to redesign the feature phone without edging into full-blown smart phone territory. So it has a fantastic screen and a feature-packed camera, but its apps are underpowered and setup is a hassle Read more
9 June 2010 by Flora Graham
CNET UK > Reviews > Mobile Phones and Apps > Mobile Phones
Sony Ericsson Elm review
Partly made from recycled plastics, the Elm is intended to let tree huggers make guilt-free phone calls on the move. Unlike some other phones in Sony Ericsson's GreenHeart range, however, the Elm doesn't skimp on features, offering much of the functionality you'd expect to see on a smart phone Read more
30 March 2010 by Patrick Steen
CNET UK > Reviews > Mobile Phones and Apps > Mobile Phones
Sony Ericsson Yari review
The Yari is a slider phone that aims to blow your mind with its gesture-controlled and motion-based games. It fell short of exploding our brains with its gaming capability, but there's no denying that it's absolutely stuffed with features, and it won't break the bank Read more
2 February 2010 by Flora Graham


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Project learning can inspire the best of high-performance teamwork, or it can be devolve into unfocused chaos. How can we support each other to keep our eye on the prize? Share your project ideas, questions, and implementation experiences.
Project-Based Learning for Primary Grades
First of all, I'd like to say that I am thrilled to have discovered Edutopia groups. Finally, a group of teachers who are inherently interested in improving their teaching practice and sharing what they know. I am very excited to learn more from all of you!
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SOURCE Academicon GmbH
LAS VEGAS, December 16, 2013 /PRNewswire/ --
According to a new report series by Academicon and PokerScout, the potential size of a regulated U.S. online poker market is $2.2 billion in the first year of operation and up to $3.3 billion by year ten. Before the federal indictment of unregulated poker in April 2011 (Black Friday), the U.S. was by far the largest market, accounting for 27% of worldwide revenue.
The study is based on an analysis of 4.6 million real money online poker players in 2009 and 2010, near the peak of unregulated poker in the U.S. The authors found that 1.4 million online poker players in the U.S. generated an average of $686 per year in revenue for poker operators, creating a $981 million market.
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Academicon is a research institution and consultancy, providing advice for regulators with a focus on online gambling. http://www.academicon.net
PokerScout is a market research company which has been publishing data on the online poker industry since 2006. http://www.pokerscout.com
Dr. Ingo Fiedler
©2012 PR Newswire. All Rights Reserved.


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5249 census
The counting of individuals, usually for the purpose of war or taxation.
Motivations for a census
To count the number of fighting men available Nu 1:1-4; Nu 26:1-4 See also Nu 1:5-49; Nu 26:5-65
For ascertaining those qualified to be included in the Jewish community Ezr 2:1-65 pp Ne 7:6-67
For purposes of taxation Lk 2:2; Ac 5:37 See also Ex 30:12
God's anger at David's unauthorised census
2Sa 24:1-9 pp 1Ch 21:1-6 David's sin in taking this census was probably that he did so from a motive of self-sufficiency rather than trusting in God.
See also
5577 | taxation |
5605 | warfare |
7230 | genealogies |


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Michigan's new-look O line about to be tested
Michigan offensive lineman Taylor Lewan (77) extends his hand to give thanks to fans crowding the stadium tunnel exit, after an NCAA college football game with Central Michigan, Saturday, Aug. 31, 2013, in Ann Arbor, Mich. Michigan won 59-9. (AP Photo/Tony Ding) |
ANN ARBOR, Mich. (AP) -- Michigan's new-look offensive line passed its first test. The next one is going to be much tougher.
After steamrolling Central Michigan 59-9 in the season opener, the 17th-ranked Wolverines face No. 14 Notre Dame in just the second night game in Michigan Stadium history.
The Wolverines had question marks coming into this season after replacing the three interior players on their offensive line. Jack Miller made his first start at center, while Graham Glasgow and Kyle Kalis debuted at guard. Miller is a redshirt sophomore, Glasgow is a former walk-on who only became a scholarship player last week, and Kalis is a redshirt freshman.
Behind them, and fifth-year senior tackles Taylor Lewan and Michael Schofield, Michigan ran for 242 yards and six touchdowns.
"Jack, Graham and Kyle — we told them that they did a nice job last week, but it gets a little tougher this week," Michigan coach Brady Hoke said Monday. "No disrespect to Central, but Notre Dame has some big guys up front who have played a lot of snaps. They line up in an odd front, so Jack's going to have a big guy directly on him, and they are really active. It's going to be a much bigger test."
Manti Te'o was the star of last season's Notre Dame game, and he's gone to the NFL, but Hoke doesn't think that is going to make life much easier for the Wolverines.
"They've pretty much got the same front seven that they had a year ago," he said. "They had a very good player who is now playing at the next level, but they've done a great job of recruiting, so it's just as good a group as it was a year ago, and you saw how much trouble they gave us."
Lewan agreed with his coach.
"Losing Te'o is tough, but that's still a really good defense," he said.
Lewan is more concerned with the distractions that his young teammates will be facing. The first night game in the Big House — two years ago against the Irish — was a massive event, and this one promises to be just as big. ESPN's College Gameday show will be at the game. Michigan hopes to break the attendance record of 114,804, set during the first primetime game between the two teams.
Lewan's task, not just as the leader of the line, but as the offensive captain, is to try to get his teammates to forget that any of that is happening.
"It's awesome that Gameday is going to be here, and there will be a lot of amazing things going on Saturday, but we need to remember that none of that is for us," he said. "That's for the fans, the media and the people watching on TV. We just need to focus on doing the same thing we do every Saturday — play a game of football. We can't worry about the lights or the fans or anything else. Just play football."
At the same time, though, Lewan knows that Saturday will be special. Not only is it his last chance to play the Fighting Irish, but it will be the last schedule visit for Notre Dame to Ann Arbor.
"This is a huge national rivalry — one of the three big ones Michigan has, along with Michigan State and Ohio," he said. "I'm going to remember these games after I'm gone as special times in my career, but I won't be thinking about that Saturday."
Notre Dame coach Brian Kelly made some headlines on Sunday when he said that he didn't consider Michigan a "historic, traditional Notre Dame" rivalry, but Hoke wasn't going to get involved in a war of words.
"He speaks for Notre Dame, and I speak for Michigan," he said. "Maybe they don't consider it a big rivalry, but we do. This is a game that started in 1887, and we've won 904 games and they are pretty close behind, so you are talking about two of the great programs in the history of the sport."
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- For Boston College, revival starts off the field


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Video: Top News
Breakingviews: Lonmin spurns Xstrata - for now (6:43)
Nov. 9 - The big platinum miner spurned 25% owner Xstrata's demand for management change in return for backing its $817mln rights issue. It can afford to, for now, says Reuters Breakingviews.
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556603 Multipack Still Water Brand Price Match - Checked Tesco.com 05/03/2014 1 1.50 C62
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The Iceni were an ancient tribe from Eastern England led by Queen Boadicea, refreshed by the invigorating local water. NATURALLY FILTERED, THEN DRAWN FROM OUR DEEP AQUIFER. Iceni is a new English natural mineral water. Filtered through deep chalk strata, it is naturally purified, with a clean, refreshing taste. Iceni is drawn from a continuously replenished aquifer in the heart of our country - so it doesn't need to travel too far to reach you. Purely English; naturally good for you.
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Component | Material | Recyclable |
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Mar 07 2014
NYIT Athletics Sets Record GPA for a Single Semester
NYIT Athletics Sets Record GPA for a Single Semester
Otis Brawley Lecture on March 5 to Highlight U.S. Medical System Problems
NYIT to Host Global Cybersecurity Conference in Abu Dhabi
NYIT Athletics to Host Summer Camps for Children
Ernie Anastos Named to Board of Trustees at NYIT
Planning for Tenure and Promotion: Institutional Expectations
Center for Communication - Creating Apps: Reaching Out in Real-Time
Center for Communication - Creating Apps: Reaching Out in Real-Time
MERMAIDS AND PIRATES, THE HULK AND IRON MAN! By Chris Bregler, CEO of Manhattan Mocap
9th Annual Nursing Spring Colloquium
New York Institute of Technology (NYIT) is committed to promoting a healthy, safe, and comfortable environment for all NYIT students, faculty, staff, and visitors, including patients visiting our academic health care centers. This policy addresses a pilot program on NYIT's New York campuses to supplement the no-smoking policy in effect within all NYIT buildings:
Signage will be posted on each campus; online maps display the smoke-free areas.
The policy is focused at reducing the health risks related to smoking and secondhand smoke for the campus community. In addition to causing direct health hazards, smoking contributes to college costs in other ways, including potential fire damage, cleaning and maintenance costs, and costs associated with absenteeism, health care, and medical insurance. Smoke-free and tobacco-free policies are becoming a standard at universities in order to support a healthy environment for the community at large.
Effective January 14, 2013, smoking is prohibited within the smoke-free zones, which are defined as and encompass the area 20 feet south of the Riland Health Care Center and extending 20 feet north of Tower House, and 20 feet west of the 500 building and 20 feet east of Serota Hall on the Old Westbury campus, and within 20 feet of the entrance of 26 West 61st St in Manhattan.
The smoke-free zone on each campus (see map) includes: exterior open spaces, loading docks, parking lots, on-campus sidewalks, streets, driveways, and in all university-owned or leased vehicles. Smoking is permitted in privately owned vehicles. Signs will be displayed in prominent, visible areas.
This policy applies to all faculty, staff, students, contractors, vendors and visitors.
All management, including administrators, deans, directors, department chairs, and supervisors will ensure that this policy is communicated to everyone within their areas of responsibility.
The success of this policy depends on the thoughtfulness and consideration of smokers and non-smokers in the defined smoke-free zones. NYIT encourages all individuals to cooperatively work together, as the responsibility lies within the NYIT community to self-enforce this policy. NYIT faculty, staff, and students who invite guests and/or visitors to campus are responsible for ensuring that their guests/visitors are aware of and comply with this policy. Visitors who do not comply with the policy are subject to having their access to campus restricted or revoked.
At times, enforcement may be necessary to aid in the adoption of this new policy, and NYIT faculty, staff, and students who are found in violation will be subject to disciplinary action. While campus security will assist in helping students and employees address violations, this policy is intended to be self-policing, and a form is available online for members of the NYIT community to report repeated violations of the policy. In accordance with the applicable law and NYIT policy, any individual can report a violation without fear of retaliation.
Ultimately, NYIT Human Resources and NYIT Office of Campus Life will be responsible for issuing warnings and/or sanctions to repeat offenders for faculty/staff violations and student violations, respectively.
NYIT's Office of Counseling and Wellness offers support groups, referrals, and educational materials for those looking to quit smoking. Following is a list of additional support services:
American Cancer Society | 800.227.2345 |
American Lung Association | 800.586.4872 |
New York State Smoker's Quitline | 866.NY.QUITS |
Nicotine Anonymous | 415.750.0328 |
North Shore LIJ Stop Smoking Classes (free) | 516.466.1980 |
St. Francis Hospital Smoking Cessation Clinic (free) | |
United HealthCare (NYIT's health care plan) | 866.374.6060 |
Approved by: President Guiliano, Dec. 6, 2012.


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This all around ruthenium-plated necklace sparkles in clear crystal in a prong setting. Offering an elegant mix between vintage and modern styles, it adds a trendy touch and is perfect for a night out.
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"Come in sit down can I get you a drink?" Pengrove asks showing the man in his office to a spare seat. The man smiles and wanders over to the chair slowly sitting down whilst taking in the surroundings.
"Uh, no, no thank you I'm fine" He replies still smiling though a little awkwardly.
"So... Adrian, is it... you want to work for us" Pengrove asks leaning back in his chair
"Um, yeah I guess" He fixes his hair as he talks the van ride wasn't so bad but the bag had really messed up the product in his hair. He keeps looking around the office newspaper clippings scatter the walls all headlined with either 'Danger' or 'Disaster', or some other overblown description.
"What is it you actually do here?" Adrian asks focusing on the picture of the shapely robot woman with darts sticking out of it.
"We are a... what would you say we do here Goran?" Pengrove asks turning and looking out the missing wall into the rest of the lab. The entire office merely a TV set like construction of three walls and a large open space.
"Gee, that's a tough one, I'd say we're a global... transition, company" Goran suggested rolling his hand. He then went back to playing with the Tesla glove he was working on.
"Global transition" Pengrove said smiling back at Adrian.
"You guys try to take over the world?" Adrian mumbled.
"Yeah... you have a problem with that" Goran asked from out in the lab
"No... I used to work at google" Adrian replied
"Oh... impressive" Pengrove mutters taking down a few notes.
humor-blogs.com has been good to me over the years...
Monday, September 14, 2009
MicroFiction: Pengrove and Goran
Pondered by Alex L upon the hour of 2:43 pm
Similar essays in the manifesto Story time
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Welcome, Gary! I'm glad it's going well for you.
Hello Everyone,
I am new to the primal existience. My son and his wife got started on it a few months ago, and when they visited us we could see the difference when they walked through the door. We asked a lot of questions, they took us to the store, showed us a lot of web stuff, and then left. It was a bit overwhelming at first, but I have been grain-free for a week. I am having some fun trying new recipes, but it is too soon to see much difference. But I feel different. I always ate salads grudgingly, but now I have one for lunch almost daily, and I look forward to it. I also feel energized at work after lunch, instead of sleepy and dull. I was doing the CW healthy diet like a lot of the success stories I have read. I couldn't lose weight even putting 400 miles on my bike second summer past. So far, it has been quite easy, and stuff I thought would tempt me has not. So, hello all, here I go.
Welcome, Gary! I'm glad it's going well for you.
Ancestral Health Info - My main blog about Primal and the general ancestral health movement for people who want to take a flexible approach.
Ok, been 2 weeks and I have lost 7 pounds. It hasn't been all that difficult, and with the continuing education on this website I am getting to where I don't even want to eat the old way and the old stuff i.e. fast food. It is also fun to find the recipes and try them out, though it is slow going as I learn to cook again. I have friends and co-workers that are keeping an eye on how I do, so I am getting extra motivation from that. Perhaps they will join me soon. Great website, and the success stories are very inspiring.


text:
Home | Membership Benefits Join Login | Talk | Seeker Books | Language English Portuguese Russian Greek
bn-study - the talk list at BN is an online study class in Theosophy. It's scope includes "ancient and modern religions philosophies and sciences", study of the specific text of Madame Blavatsky, and general issues such as "living the life". It is Blavatsky-centered.
For general info on this list visit welcome message. Participants in BN-study can visit the entire archives.
To join the class, signup for membership (free) in Blavatsky Net, and check "yes" on your membership record for BN-study. While signing up, choose the normal, or digest, or other forms of participation. (And while you are doing it, choose whatever other benefits you would like.)
The talk list is assembling some of the results of their discussion and those results are available at "matrix".
"No Religion Higher Than Truth" Support this site by visiting our store at www.seekerbooks.com. Largest selection of Theosophical books with many books up to 30% discount. Site copyright © 1996-2004 by Reed Carson


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Family Dollar Beats Estimate Despite Flat Q4 CompsWednesday October 9th, 2013 - 11:14AM
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For the fourth quarter, ended August 31, Family Dollar Stores, Inc. announced net income of $102.2 million, or 88 cents per diluted share, versus $80.9 million, or 69 cents per diluted share, in the year-prior period. For the full 53-week fiscal year, according to the retailer, net income was $443.6 million, or $3.83 per diluted share, versus $422.2 million, or $3.58 per diluted share, for the 52-week year earlier. Fourth-quarter net income included a one-time $5 million favorable adjustment related to a change in accounting for vendor allowances, Family Dollar stated. Excluding this adjustment and a litigation charge of $11.5 million in the fourth quarter of fiscal 2012, earnings per diluted share in the fourth quarter of fiscal 2013 would have increased to 86 cents versus 75 cents in fiscal 2012. Excluding the accounting adjustment in fiscal 2013 and the litigation charge in fiscal 2012, earnings per diluted share would have increased to $3.80 at the end of the most recently completed fiscal year versus $3.64 in in the year earlier. Family Dollar estimated that the extra week in the current fiscal year contributed approximately $189 million in sales and seven cents of earnings per diluted share. A Zacks consensus analyst estimate called for adjusted earnings per diluted share of 84 cents. In the fourth quarter, the company noted, total net sales increased 5.8% to $2.5 billion while comparable store sales were flat. Both customer traffic and the average customer transaction value were flat during the quarter, Family Dollar pointed out. Consumables category sales came in strongest, up 8.3% in the quarter, driven primarily by growth in refrigerated and frozen food, health aids and tobacco, the company reported. Fourth quarter operating profit advanced 23.9% to $155.6 million, or 6.2% of net sales, year over year, while adjusted operating profit was $150.6 million, or 6% of net sales, compared $137.1 million, or 5.8% of net sales, in fiscal 2012, the company maintained. For the fiscal year, net sales increased 11.4% to $10.39 billion, while comps increased 3%. The gain resulted from increased customer traffic and an increase in the average customer transaction value, Family Dollar pointed out. Again, the consumables category performed best, up 16.9% over the year, driven primarily by strong growth in food, health and beauty aids and tobacco. Posted operating profit in fiscal 2013 was $688 million, or 6.6% of net sales, compared with $664.2 million, or 7.1% of net sales, in the prior year. Adjusted operating profit in fiscal 2013 was $683 million, or 6.6% of net sales, compared with $675.7 million, or 7.2%, in fiscal 2012. During fiscal 2013, Family Dollar opened 500 new stores, closed 26 and renovated, relocated or expanded 830, the company asserted. Family Dollar operates about 7,900 stores in 46 of the United States. Tags: Family Dollar • fiscal year • fourth quarter • zacks • net income • sales • comparable store sales • Housewares • Cookware & Bakeware • Health & Personal Care • Home Décor • Organization & Cleaning • Tabletop • Gadgets & Kitchen Tools • Retail • Financials • |
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Congratulations to the winners of the 2014 Housewares Designs Awards. One of the most rewarding aspects of hosting the Housewares Design Awards during the past 11 years has been the delight and gratitude of the winners and finalists whose products are displayed during the annual gala and awards ceremony.


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Friday, March 1 @ 10:15 am
We're doing a year-long celebration of Florida literature and starting it off with a bang! Our March book: Their Eyes Were Watching God by Zora Neale Hurston. Join us as we discuss the adventures and loves and losses of Janie, the book's protagonist, and her life in 1930s Florida. Please pick a favorite quote or line from the book and bring it with you to the discussion.


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Marineland introduces the Aquatic Plant LED. In addition to the 1 watt 6,500K LEDs, each light comes packed with 3 watt RGB LEDs that provide 460nm blue, 660nm red, and green accent lighting to make your aquatic plants thrive, keeping them healthy and lush. Features our new integrated timer as well as our newly-designed dispersion lens. Finally your aquatic plants have the light they have been waiting for, in a modern, streamlined design.
LIMITED WARRANTY: Within one year from the date of original purchase, Marineland Aquarium Products will repair or replace, at its option, any LED Lighting System which is deemed defective in workmanship or materials. Please return the unit, together with proof of date of purchase. Call 800-322-1266 for return authorization and shipping address. Damage or injuries resulting from negligence or misuse are not covered by this warranty. Incidental or consequential damages are specifically excluded*. This warranty gives you specific legal rights. You may also have other rights which vary from state to state.
5202671 - 5.812 x 26.375 X 2.875
Because some states do not allow the exclusion of incidental or consequential damages, this exclusion may not apply to you.


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- Ligand-Specific Interactions Modulate Kinetic, Energetic, and Mechanical Properties of the Human β2 ...
Ligand-Specific Interactions Modulate Kinetic, Energetic, and Mechanical Properties of the Human β2 Adrenergic Receptor
Structure, Volume 20, Issue 8, 8 August 2012, Pages 1391-1402
Michael Zocher, Juan J. Fung, Brian K. Kobilka and Daniel J. Müller
SummaryG protein-coupled receptors (GPCRs) are a class of versatile proteins that transduce signals across membranes. Extracellular stimuli induce inter- and intramolecular interactions that change the functional state of GPCRs and activate intracellular messenger molecules. How these interactions are established and how they modulate the functional state of GPCRs remain to be understood. We used dynamic single-molecule force spectroscopy to investigate how ligand binding modulates the energy landscape of the human β2 adrenergic receptor (β2AR). Five different ligands representing either agonists, inverse agonists or neutral antagonists established a complex network of interactions that tuned the kinetic, energetic, and mechanical properties of functionally important structural regions of β2AR. These interactions were specific to the efficacy profile of the ligands investigated and suggest that the functional modulation of GPCRs follows structurally well-defined interaction patterns.
Summary | Full Text | PDF (1418 kb) - Restructuring G-Protein- Coupled Receptor Activation
Restructuring G-Protein- Coupled Receptor Activation
Cell, Volume 151, Issue 1, 28 September 2012, Pages 14-23
Martin Audet and Michel Bouvier
SummaryG-protein-coupled receptors serve as key signal transduction conduits, linking extracellular inputs with diverse cellular responses. These receptors eluded structural characterization for decades following their identification. A landmark structure of rhodopsin provided a basis for structure-function studies and homology modeling, but advances in receptor biology suffered from a lack of receptor-specific structural insights. The recent explosion in GPCR structures confirms some features predicted by rhodopsin-based models, and more importantly, it reveals unexpected ligand-binding modes and critical aspects of the receptor activation process. The new structures also promise to foster studies testing emerging models for GPCR function such as receptor dimerization and ligand-biased signaling.
Summary | Full Text | PDF (4630 kb) - Ligand-Dependent Perturbation of the Conformational Ensemble for the GPCR β2 Adrenergic Receptor Rev...
Ligand-Dependent Perturbation of the Conformational Ensemble for the GPCR β2 Adrenergic Receptor Revealed by HDX
Structure, Volume 19, Issue 10, 12 October 2011, Pages 1424-1432
Graham M. West, Ellen Y.T. Chien, Vsevolod Katritch, Jovylyn Gatchalian, Michael J. Chalmers, Raymond C. Stevens and Patrick R. Griffin
SummaryMechanism of G protein-coupled receptor (GPCR) activation and their modulation by functionally distinct ligands remains elusive. Using the technique of amide hydrogen/deuterium exchange coupled with mass spectrometry, we examined the ligand-induced changes in conformational states and stability within the beta-2-adrenergic receptor (β2AR). Differential HDX reveals ligand-specific alterations in the energy landscape of the receptor's conformational ensemble. The inverse agonists timolol and carazolol were found to be most stabilizing even compared with the antagonist alprenolol, notably in intracellular regions where G proteins are proposed to bind, while the agonist isoproterenol induced the largest degree of conformational mobility. The partial agonist clenbuterol displayed conformational effects found in both the inverse agonists and the agonist. This study highlights the regional plasticity of the receptor and characterizes unique conformations spanning the entire receptor sequence stabilized by functionally selective ligands, all of which differ from the profile for the apo receptor.
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Copyright © 2013 Elsevier Inc. All rights reserved.
Cell, Volume 152, Issue 3, 532-542, 31 January 2013
Add/View Comments (0)The Dynamic Process of β2-Adrenergic Receptor Activation
Rie Nygaard1, 6, Yaozhong Zou1, 6, Ron O. Dror3, Thomas J. Mildorf3, Daniel H. Arlow3, Aashish Manglik1, Albert C. Pan3, Corey W. Liu2, Juan José Fung1, Michael P. Bokoch1, Foon Sun Thian1, Tong Sun Kobilka1, David E. Shaw3, Luciano Mueller5, R. Scott Prosser4 and Brian K. Kobilka1, ,
1 Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA
2 Stanford Magnetic Resonance Laboratory, Stanford University School of Medicine, Stanford, CA 94305, USA
3 D.E. Shaw Research, New York, NY 10036, USA
4 Department of Chemistry, University of Toronto, UTM, Mississauga, Ontario L5L 1C6, Canada
5 Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543, USA
6 These authors contributed equally to this work
Graphical Abstract
► NMR using 13CH3-ε-Met reveals dynamics of β2 adrenergic receptor (β2AR) ► NMR and computational approaches show unanticipated conformational states ► Conformational heterogeneity is observed in both unliganded and antagonist-bound β2AR ► Agonist alone does not fully stabilize the active conformation of the β2AR
- G-protein-coupled receptors (GPCRs) can modulate diverse signaling pathways, often in a ligand-specific manner. The full range of functionally relevant GPCR conformations is poorly understood. Here, we use NMR spectroscopy to characterize the conformational dynamics of the transmembrane core of the β2-adrenergic receptor (β2AR), a prototypical GPCR. We labeled β2AR with 13CH3ε-methionine and obtained HSQC spectra of unliganded receptor as well as receptor bound to an inverse agonist, an agonist, and a G-protein-mimetic nanobody. These studies provide evidence for conformational states not observed in crystal structures, as well as substantial conformational heterogeneity in agonist- and inverse-agonist-bound preparations. They also show that for β2AR, unlike rhodopsin, an agonist alone does not stabilize a fully active conformation, suggesting that the conformational link between the agonist-binding pocket and the G-protein-coupling surface is not rigid. The observed heterogeneity may be important for β2AR's ability to engage multiple signaling and regulatory proteins.


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The Orthodox presence in New Orleans dates to the middle of the 19th century, when Jewish arrivals from Eastern Europe began to settle in the city. They brought little with them, except for their traditional Orthodox practices and a determination to recreate their close-knit communities in a foreign land. Many of the arrivals to New Orleans settled in the Dryades Street neighborhood, six blocks of two story row houses stretching along Dryades from Howard to Jackson Avenue. Subsequent arrivals settled alongside friends and family from the old country, and the neighborhood quickly evolved into the nexus of the New Orleans Orthodox Jewish population. By the late 1800s, a visitor walking down Dryades Street would smell the aromas of Eastern European dishes wafting from the humble residences and would hear colorful Yiddish expressions exchanged outside the numerous Kosher delicatessens, butchers and bakeries.
In 1858, the earliest arrivals from Poland and Prussia established an Orthodox congregation, named Tememe Derech, or "The Right Way." The congregation soon became known as simply "the Polish Congregation." As Jews from other Eastern Europeans regions began to arrive, they tended to congregate with their fellow countrymen, and establish services in accordance with local traditions. By the end of the 1800s, the Dryades Street neighborhood contained a number of small regional congregations, including the Galitzeaner congregation Chevra Thilim, a Litvak congregation Chevra Mikve Israel, and a Lithuanian Chasidic congregation named Anshe Sfard. These smaller congregations met in private homes and rented spaces and often had just enough attendees for a minyan, a quorum of ten members.
Over time, the nuances of specific regional divisions gradually softened, and in 1904 a number of the small congregations, social aid organizations, and an early burial society merged with Tememe Derech, to create a single Orthodox Congregation, named Beth Israel. The new congregation commenced holding services in a building on the 500 block of Carondelet Street while raising funds for permanent synagogue. Members elected David Rosenson to serve as Beth Israel's first president. Rosenson had immigrated from Russia in 1899 along with his wife and four children. Perhaps his experience moving halfway across the world with a family of six inspired his interest in luggage, for upon his arrival in New Orleans he established himself as a valise maker. By 1910, he owned a suitcase factory, which he managed along with his son Jacob. At the time of his presidency at Beth Israel, Rosenson lived near Beth Israel's meeting space on Carondelet, but by the 1920s, after achieving success in manufacturing, Rosenson moved his family further uptown to a home on Josephine Street.
After meeting in rented spaces, the congregation soon began raising funds to acquire a permanent place of worship. Although the Orthodox residents of the Dryades Street neighborhood generally maintained limited contact with the more socially established Reform Jews living a few blocks away along St. Charles Avenue, Beth Israel's fundraising effort afforded an opportunity for cooperation between the groups. On January 13, 1905, Beth Israel President I.L. Haskel published an appeal to the whole Jewish community in the Jewish Ledger newspaper, stating: "The Orthodox Jewish community of our city is without a suitable place of worship … we appeal to Orthodox and Reform alike … wherefore we all should help us establish and Orthodox Synagogue worthy of its name and worthy of the generous community in which we live." The Reform community responded generously, and later that year Beth Israel moved into a Spanish plantation home at 1616 Carondelet once owned by a former mayor of New Orleans, Joseph Shakespeare. A mere two years after signing the congregation's charter, Beth Israel inaugurated the new synagogue in time for the 1906 High Holy Day services. In 1924, they tore down the house and built a beautiful new synagogue on the same site.
After moving into the Carondelet Street synagogue, Beth Israel experienced rapid growth. By 1910, the Beth Israel congregation consisted of 180 families and was the second largest congregation in the city; it grew to 250 families by 1914. From this period through World War II, Beth Israel considered itself the largest Orthodox congregation in the South.
During the early 1900s, the numerous small Orthodox groups consolidated into three congregations, all large enough to purchase permanent houses of worship. In addition to Beth Israel, the Galitzeaner synagogue Chevra Thilim built a small synagogue nearby at 826 Lafayette Street in 1915 and the Lithuanian Congregation Anshe Sfard purchased a small building in 1900 at 1309 South Rampart.
These early decades of the 1900s marked a golden era for the Dryades Street neighborhood. Many of the new arrivals worked initially as peddlers, based out of dry good stores owned by more established neighbors. Their territories often included underserved parts of the town, including the poorer black neighborhoods. Others worked as butchers or in the New Orleans shipyards, or as tailors, coopers, clerks, laborers, bookkeepers and merchants. The members of the Orthodox community used their increasing economic success to support a broader range of congregational functions and reinforce a vibrant Jewish presence in the neighborhood. In 1915, Beth Israel congregants helped establish the "Talmud Torah" or "Communal" school at the corner of Clio and Josephine Streets. The daily afternoon Hebrew classes attracted members of both the Reform and the Orthodox Jewish communities. According to some accounts, in the 1920s, the Jewish population of Dryades Street reached an estimated 3,500 inhabitants.
The financial prosperity enjoyed in the 1920s allowed congregants to build larger houses of worship. In 1925, members of Congregation Anshe Sfard built a large new synagogue at 2230 Carondelet that still stands today. In 1924, Beth Israel built an ornate and imposing synagogue at the site of their original building. The large Byzantine structure featured a seating capacity of 1200 and flourishes such as hand carved Stars of David in the ceiling, a large imported chandelier, and stained glass windows. At the dedication on Sept. 12, 1924, Rabbi Henry Raphael Gold of Boston came to speak, and was so impressed that he ended up staying as the congregation's rabbi. In 1926, Gold expanded Beth Israel's reach by establishing the Menorah Institute, the educational, social and cultural arm of the congregation. Housed in a separate building, the Menorah Institute provided a fully Orthodox alternative to the Communal Hebrew School and housed auxiliary prayer services, which earned the building the name "The Little Shul."
Beth Israel continued to grow through the 1930s, under the leadership of Rabbi Uri Miller. Membership expanded to approximately 350 families and the congregation added cemetery properties, founded a nursery school, and established a junior congregation.
The same economic success that contributed to the vibrancy of the Dryades Street neighborhood ultimately precipitated its demise, as the children of the East European immigrants gradually moved uptown, into the Lakeview area, and to neighboring suburbs. Following World War II, the three Orthodox congregations all suffered from reduced membership as more and more of their congregants left the neighborhood. In 1948, Chevra Thilim build a new synagogue further uptown, at the corner of South Claiborne and Jena Streets, a move that encouraged increasing numbers of Jewish families to make the move uptown. In 1963, Beth Israel purchased a property in the Lakeview neighborhood, at 7000 Canal Boulevard. Congregants celebrated the new building's formal dedication in 1971. Anshe Sfard remains the only Orthodox congregation still operating in the Dryades Street neighborhood, albeit with a significantly diminished membership and range of communal functions.
In the 1950s, the rise of Conservative Judaism and innovations introduced to traditional ritual practices led to serious disagreements among the congregants of Chevra Thilim. In 1955, the Chevra Thilim Board of Directors voted to introduce mixed seating, a move adopted by some traditional congregations across the country. Two weeks later, thirty nine members of the congregation, led by Harry Katz, brought a suit in the Civil District Court for the Parish of Orleans. The plaintiffs claimed that by introducing mixed seating, the board of directors had violated the precepts of halacha and therefore violated the congregation's charter to worship in "the Orthodox Polish Jewish tradition."
After a lower court ruled in favor of Katz, the case eventually made its way to the Louisiana Supreme Court. The Chevra Thilim disagreement was not an isolated event in the Orthodox Jewish world; at the time of Katz vs. Singerman, the subject of mixed-seating in Orthodox congregations sparked controversy and confusion in congregations across the country. Many Orthodox Jews from around the country carefully followed the proceedings and considered it one of the first major tests of mixed-seating innovations. A number of these people even took an active role in the Chevra Thilim case. 27 Orthodox rabbis from around the country filed affidavits before the Louisiana Supreme Court affirming that mixed seating "is not contrary to Orthodox Jewish forms and ceremonies." Katz and his team produced a list of 75 affidavits and presented many witnesses testifying that it was. The Louisiana Supreme Court eventually overturned the lower court's decision, and determined that despite the introduction of mixed seating, "Congregation Chevra Thilim and the defendants here continue to profess to worship God according to the Orthodox forms and ceremonies."
Although the court ruled in favor of allowing mixed-seating within the Orthodox congregation, the issue remained far from settled among congregants. Following the case, the congregation split. The members advocating mixed seating ultimately left Chevra Thilim, and founded New Orleans' first Conservative congregation, Tikvat Shalom. Soon after the case, the question of mixed seating in Orthodox congregations evaporated as separate seating emerged as a definitive and necessary element of Orthodox prayer services. Following the case, Chevra Thilim remained Orthodox and preserved separate seating, but continued to lose members as families moved away from the neighborhood. Chevra Thilim eventually did adopt mixed seating, but still could not stave off the membership attrition. In 1999, the two congregations reunited and formed Shir Chadash, a Conservative congregation with traditional leanings.
Today, Shir Chadash, Beth Israel, and Anshe Sfard continue to serve more traditionally minded New Orleans Jews, along with two different Chabad Houses. Hurricane Katrina flooded Beth Israel's synagogue in Lakeview, destroying its Torah Scrolls and most other religious artifacts. Rising above this devastation, Beth Israel has begun to meet in the chapel at the Reform Gates of Prayer congregation in Metairie. They have acquired a home in the area to be used by their new rabbi Uri Topolowsky and are working to build a new synagogue. Orthodox Judaism in New Orleans has often been overshadowed by the larger Uptown Reform Temples. Maintaining traditional practice in a city known for its treyf seafood and carefree attitude has often been a challenge, but these traditional congregations continue to persevere.


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I just returned from an incredibly helpful and fun annual appraisal conference in Texas. I was asked to make a presentation and ended up joining their board of directors. I've been a member of RAC (Relocation Appraisers & Consultants) for about 20 years and even though the organization started out with a primary emphasis on… Read More
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I mentioned in another thread how I want to see Schlarman's work on the field. Here is a link of some footage against Mississippi State this past season (listen closely to the announcers praise for Schlarman) and here also is a number of quotes from a Troy football forum which I don't think I am allowed to link...
Testament to John Schlarman
I have said for years he is the best on our staff. Great guy too.
I wish more coaches on our staff were as good at what they do as Coach Schlarman.
John Schlarman is an excellant offensive line coach and has been from the day he arrived. It's a testament that not only are the first team players ready to play, but when a first teamer gets injured and the second team replacement comes in, that O-line continues to hum like a well oiled machine. Sure, there may be a few hiccups, but overall, he has that line performing each and every year.
Troy is very fortunate to have this guy. I hope we continue to keep him for a long time.
I thought the O line did a great job last night, no sacks, generally Corey had plenty of time, blew some big holes for Southward against a big SEC defensive front. I noticed that MSU ran a lot of situational plays, subbing on 3rd and short, third and long, and no matter what they threw at us the O line to continued to handle their roles welll.
Now, are you guys wanting to see his work on the field as much as I am?
ESPN Video: Shawn Southward rush up the middle for 3 yards for a TOUCHDOWN.
espn.go.comI think Troy was primarily air raid variant but look at te rushing against MSU...
223 yards on 40 carries for an average of 5.6 ypc with 3 TDs and a long of 31.
We will run the ball this year. :D
NCAA College Football Box Score
scores.espn.go.comI've had the pleasure of seeing John Schlarman present his coaching clinic several times at the Tony Franklin System Seminar and he is very impressive. The pass protection and run game schemes are actually pretty simple so it allows for lots of practice reps and allows the offense to play fast during games. The running game really only has four plays, stretch, zone, power and draw. Despite that Troy put up some consistently impressive rushing seasons (except for 2011) during Schlarman's time at Troy. I think y'all will be very impressed with O-line play this season. The stats Schlarman's o-line helped produce at Troy are pretty impressive:
Rushing Yards:
2012 - 2007 rushing yards
2011 - 1064
2010 - 2036
2009 - 1939
2008 - 2179
2007 - 2191
Sacks against:
2012 - 15 in 509 attempts
2011 - 20 in 531
2010 - 24 in 528
2009 - 24 in 529
2008 - 13 in 524
2007 - 18 in 517
247Sports In partnership with CBS Sports


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IDEA Tech V4 Hybrid
A hybrid as hot as a driver.The Idea Tech V4 Hybrids are the most technically advanced, easiest-to-hit hybrids that Adams has ever engineered. The advancements of velocity slots, now featuring Cut-Thru Slot™ Technology, achieves the same CT of a driver, which delivers higher ball speeds, more forgiveness and more distance. With innovation like this, the Idea Tech V4 Hybrid is as hot as your driver.
Find a Demo Day in your area and try out the IDEA Tech V4 Hybrids
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a Hybrid as hot as a driver.
With continuous refinements being made in club design, and specifically for hybrid design, the technology has evolved quickly, and never more apparent than with the Idea Tech V4 hybrids. This new design has Velocity Slots in the crown and sole of the club, and also features a channel that is literally cut through the head of the club from the top slot to the bottom allowing for even more face deflection. It was important to seal the slots in order to be compliant with USGA regulations, so the Idea Tech V4 hybrids feature a TPU insert which also improves the feel and give the hybrids a very crisp sound similar to that of an iron.
Designers are able to optimize Velocity Slots Technology in the Idea Tech V4 hybrids by isolating each slot shaping parameter, including the thru-slots resulting in the maximized CT. With the introduction of the original Velocity Slot Technology in the Idea a12 OS hybrids, engineers saw an increase in CT of 20% vs. the Idea Tech V3 hybrids. With the use of Thru Slots in the new Idea Tech V4 hybrids, engineers have achieved an increase in CT of 67% to levelsonly seen before in today's titanium drivers, but done in a stainless steel hybrid. In addition to the hotness of the face, the Idea Tech V4 uses a multi-material construction featuring tungsten heel/toe perimeter weighting in the long irons provides optimal CG location for increased forgiveness & higher launch.
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6 Hybrid | 28º | 61.5º | 38.25" | D1 | R L |
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Film School are not technically a new act--they formed in San Francisco in 1998, and their first album came out in 2001--but after a three-year recording hiatus and a few lineup changes, they sure sound like a band reborn.
While the dreampop quintet's just-released fourth album, Fission, features the same band members that played on 2007's Hideout, Fission's fizzy, fuzzy sound is notably different--more "pop" than "dream." Yes, Film School's gazes remain unblinkingly focused on their shoes (their usual influences--Jesus & Mary Chain, My Bloody Valentine, Lush--are still easily discernible here), but they've also expanded their musical vision, adding beats and synths for a lighter, groovier, more modern vibe. Much of this sonic makeover is due to the the increased participation of angel-voiced bassist Lorelei Plotczyk (pictured flipping her hair at right), who joined Film School for Hideout and on this latest release contributes some of the finest tracks. Her ethereal, lush/Lush vocals are front-and-center on the first single, "Heart Full Of Pentagons," for instance, and the Plotczyk-penned second single, "Sunny Day," is an irresistible burst of jangle-pop effervescence that, with its mix of bright Byrdsy guitars and cool Britpop ennui, is the perfect soundtrack for summer morphing into autumn.Below, check out Fission's first video, "Sunny Day"--shot by band leader Greg Bertens in Silver Lake as a sort of lo-fi love letter to Film School's adopted home turf of Los Angeles--as well as the propulsive "Heart Full Of Pentagons." If you weren't familiar with this band before, it's time to get schooled.
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Save spare change while decorating the nursery with this girls' C.R. Gibson floral piggy bank. In pink.
Product Features:
- Comes in a cute box for easy gift-giving.
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- 8.8"H x 8.1"W x 8.7"D
- Promotional offers available online at Kohls.com may vary from those offered in Kohl's stores.


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Q: Where can I register for the basic tier of service?
A: Please follow this link to register for the FanFeedr API basic tier of service.
Q: What does "FanFeedr URL" mean?A: The URL's returned by requests to the basic and daily tiers return the same URL for content items as FanFeedr.com displays them, for example this story. FanFeedr URL's wrap the original content in an iFrame to provide super-simple access to share or comment on the item as well as provide information back to FanFeedr on what stories are getting the most traffic. Calls from the Gold and Platinum tiers return the original item URL. So instead of the above, this URL would be returned.