text:
Single Dose Study of Controlled-Release Paroxetine Tablets in Healthy Japanese Male Subjects
This study has been completed.
Information provided by (Responsible Party):
ClinicalTrials.gov Identifier:
First received: July 9, 2009
Last updated: April 5, 2012
Last verified: February 2011
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- No Study Results Posted
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- How to Read a Study Record
Detailed Description:
The primary purpose of this study is to to assess the pharmacokinetics of paroxetine after single doses of paroxetine CR at the dose levels of 12.5, 25 and 50mg in healthy Japanese male volunteers.
Condition | Intervention | Phase |
Depressive Disorder Healthy Volunteer |
Drug: paroxetine CR |
Phase 1 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Pharmacokinetics Study Intervention Model: Crossover Assignment Masking: Open Label |
Official Title: | An Open Label, Randomized, Three-period Crossover Study to Compare the Pharmacokinetic Profile of Paroxetine After Single Doses of the Controlled-release Paroxetine Tablets at the Dose Levels of 12.5, 25 and 50mg in Healthy Japanese Male Subjects |
Resource links provided by NLM:
MedlinePlus related topics:
Drug Information available for:
Paroxetine hydrochloride
Paroxetine hydrochloride hemihydrate
Paroxetine Mesylate
U.S. FDA Resources
Further study details as provided by GlaxoSmithKline:
Primary Outcome Measures:
- Pharmacokinetic parameters of plasma paroxetine after single doses of paroxetine CR at 12.5mg, 25mg and 50mg in healthy Japanese male volunteers [ Time Frame: up to 120 hours after a single dose in all dosing sessions ] [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Safety and tolerability after single doses of paroxetine CR at 12.5mg, 25mg and 50mg in healthy Japanese male volunteers [ Time Frame: up to 120 hours after a single dose in all dosing sessions ] [ Designated as safety issue: No ]
Enrollment: | 18 |
Study Start Date: | July 2009 |
Study Completion Date: | September 2009 |
Primary Completion Date: | September 2009 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: Open label treatment with 3-period crossover design |
Drug: paroxetine CR
3-period crossover single dosing at the dose levels of 12.5, 25 and 50mg into healthy volunteers
Detailed Description:
This clinical trial is to characterize the pharmacokinetic profile after single oral doses of the proposed final market tablet formulations of paroxetine CR in Japan (the 12.5mg and 25mg tablets), at the dose levels of 12.5, 25 and 50mg in the healthy male Japanese volunteers. Treatment sequence of the 3 dose levels in each subject is randomized.
Ages Eligible for Study: | 20 Years to 64 Years |
Genders Eligible for Study: | Male |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Healthy Japanese adult males between 20 and 64 years of age inclusive
- BMI 18.50 or higher and < 25.00 kg/m2, and bodyweight 50 kg or higher
- Non-smokers
- AST, ALT, ALP, gamma-GTP and total-bilirubin are below the upper limit of normal range
- QTc(B) interval <450 msec
- Able to attend all visits and complete the study
- Capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the consent form
Exclusion Criteria:
- Any clinically relevant abnormality on the screening physical examination, vital signs, 12-lead ECG and/or clinical laboratory tests
- Medical history that is not considered as eligible for inclusion in this study by the investigator
- Current or chronic history of liver disease, or known hepatic or biliary abnormalities (with the exception of asymptomatic gallstones)
- History of psychiatric disorder or suicide attempts or behaviours
- History or presence of gastrointestinal, hepatic or renal disease or any other condition known to interfere with the absorption, distribution, metabolism or excretion of drugs
- History of sensitivity to any of the paroxetine formulations, or components thereof
- Positive for urine drug screening
- Participation in another clinical study or post-marketing study in which the subject is or will be exposed to an investigational or a non-investigational product or device
- Participation in a clinical study or post-marketing study with an investigational or a non-investigational product or device within 4 months of preceding the first dose of study medication
- History of drug or other allergy, or idiosyncrasy, excluding a pollen allergy without current symptoms
- History of drug abuse, or current conditions of drug abuse or alcoholism
- History of regular alcohol consumption exceeding, on average, 14 drinks/week (1 drink = 150 mL of wine or 350 mL of beer or 45 mL of 80 proof distilled spirits) within 6 months of screening
- Use of prescription or no-prescription drugs, including vitamins, crude drug, herbal and dietary supplements (including St John's Wort) within 14 days prior to the first dose of study medication
- Unwillingness or inability to follow the procedures outlined in the protocol
- Consumption of grapefruit or grapefruit-containing products from 7 days prior to the first dose of study medication
- Positive for syphilis, HIV antibody and antigen, Hepatitis B surface antigen, Hepatitis C antibody or HTLV-1 antibody
- Donation of blood in excess of 400mL within the previous 4 months or 200mL within the previous 1 month to the first dose of study medication
Contacts and Locations
More Information
No publications provided
Keywords provided by GlaxoSmithKline:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on March 09, 2014
No publications provided
Responsible Party: | GlaxoSmithKline |
ClinicalTrials.gov Identifier: | NCT00938184 History of Changes |
Other Study ID Numbers: | 112811 |
Study First Received: | July 9, 2009 |
Last Updated: | April 5, 2012 |
Health Authority: | Japan: Pharmaceutical and Medical Device Agency |
Keywords provided by GlaxoSmithKline:
pharmacokinetics tolerance Japanese healthy male subjects controlled-release tablet |
single dose safety paroxetine |
Additional relevant MeSH terms:
Depressive Disorder Depression Mood Disorders Mental Disorders Behavioral Symptoms Paroxetine Serotonin Uptake Inhibitors Neurotransmitter Uptake Inhibitors Neurotransmitter Agents |
Molecular Mechanisms of Pharmacological Action Pharmacologic Actions Serotonin Agents Physiological Effects of Drugs Antidepressive Agents, Second-Generation Antidepressive Agents Psychotropic Drugs Central Nervous System Agents Therapeutic Uses |
ClinicalTrials.gov processed this record on March 09, 2014


text:
Geographic complexity explains patterns of spread of white-nose syndrome in bats, study finds
(Phys.org)—The spread of white-nose syndrome, an emerging fungal disease in bats, may be determined by habitat and climate, scientists at the University of Georgia have found.
Scientists stake out bat colonies to track a killer: White nose syndrome
As green cricket frogs screeched and the sun set, researcher Kate Langwig and a small band of fellow scientists set a trap of black nets to nab bats and inspect them as part of a scientific quest to understand a spreading ...
Chemical fingerprinting tracks the travels of little brown bats
They're tiny creatures with glossy, chocolate-brown hair, out-sized ears and wings. They gobble mosquitoes and other insect pests during the summer and hibernate in caves and mines when the weather turns cold. ...
Early spring means more bat girls
There must be something in the warm breeze. A study on bats by a University of Calgary researcher suggests that bats produce twice as many female babies as male ones in years when spring comes early.
Bats rebound in NY caves first hit by white-nose
(AP) -- Researchers found substantially more bats in several caves that were the first ones struck by white-nose syndrome, giving them a glimmer of hope amid a scourge that has killed millions of bats in ...
Study: Fungus behind bat die-off came from Europe
The mysterious deaths of millions of bats in the United States and Canada over the past several years were caused by a fungus that hitchhiked from Europe, scientists reported Monday.
Up to 6.7 million bats dead from fungus: US
Between 5.7 and 6.7 million bats have died in North America due to a fungus known as white-nose syndrome (WNS) since the disease first appeared in 2006, US authorities said on Tuesday.
Fungus causes white-nose syndrome in bats, researchers confirm
(PhysOrg.com) -- Scientists have proven that the fungus Geomyces destructans causes white-nose syndrome, a fast-spreading and highly lethal disease of bats.
Unlocking the mystery of the disappearing bats
A McMaster researcher is working to pull one of North America's most common bats back from the brink of extinction.
Big city holds empty promise for bats
In the treeless, flat Prairie, you'd think a city would provide a good home for bats who like to snuggle up and roost in trees and buildings. But researchers at the University of Calgary made the surprising ...
Fungus sweeps across the country, killing bats
More than 100 hibernating bats hang from the vaulted ceiling of a chilly gallery in central New Mexico's Fort Stanton Cave, seemingly unaware of the lights from helmet lanterns sweeping over their gargoyle-like faces.
Food forensics: DNA links habitat quality to bat diet
Biologists head to bunkers to fight bat disease
(AP) -- Biologist Susi von Oettingen walked into the dark World War II-era military bunker and took out her flashlight. Among the old pipes, wires and machinery parts, she saw some bats hanging from cracks ...
Interim protections sought for little brown bats
Scientists and conservation groups filed a formal request today asking the U.S. Fish and Wildlife Service to determine if little brown bats, once the most common bat species in the Northeast, need protection under the Endangered ...

subset: commoncrawl


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Article provided by Springer in its journal Test.
Volume (Year): 7 (1998)
Issue (Month): 2 (December)
Pages: 283-285
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- Huang, Hsin-Cheng & Cressie, Noel, 1996. "Spatio-temporal prediction of snow water equivalent using the Kalman filter," Computational Statistics & Data Analysis, Elsevier, vol. 22(2), pages 159-175, July.
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- Herrendorf, Berthold & Manfred J. M. Neumann, 1997.
"A Non-normative Theory of Inflation and Central Bank Independence,"
Discussion Paper Serie B
400, University of Bonn, Germany.
- Berthold Herrendorf & Manfred Neumann, 2000. "A nonnormative theory of inflation and central bank independence," Review of World Economics (Weltwirtschaftliches Archiv), Springer, vol. 136(2), pages 315-333, June.
- Herrendorf, B. & Neumann, M.J.M., 1998. "A non-Normative Theory of Inflation and Central Bank Independence," The Warwick Economics Research Paper Series (TWERPS) 515, University of Warwick, Department of Economics.
- Yongsung Chang & Jay H. Hong, 2003.
"On the Employment Effect of Technology: Evidence from US Manufacturing for 1958-1996,"
0307004, EconWPA.
- Yongsung Chang & Jay H. Hong, 2003. "On the employment effect of technology : evidence from U.S. manufacturing for 1958-1996," Working Paper 03-06, Federal Reserve Bank of Richmond.
- Yongsung Chang & Jay H. Hong, 2003. "On the Employment Effect of Technology: Evidence from US Manufacturing for 1958-1996," PIER Working Paper Archive 03-004, Penn Institute for Economic Research, Department of Economics, University of Pennsylvania.
- Fabrice Collard & Harris Dellas, 2002.
"Technology Shocks and Employment,"
dp0217, Universitaet Bern, Departement Volkswirtschaft.
- Fabrice Collard & Harris Dellas, 2007. "Technology Shocks and Employment," Economic Journal, Royal Economic Society, vol. 117(523), pages 1436-1459, October.
- Collard, Fabrice & Dellas, Harris, 2003. "Technology Shocks and Employment," CEPR Discussion Papers 3680, C.E.P.R. Discussion Papers.
- Michael Feroli, 2004. "Monetary policy and the information content of the yield spread," Finance and Economics Discussion Series 2004-44, Board of Governors of the Federal Reserve System (U.S.).
- Domenico J. Marchetti & Francesco Nucci, 2007.
"Pricing Behavior and the Response of Hours to Productivity Shocks,"
Journal of Money, Credit and Banking,
Blackwell Publishing, vol. 39(7), pages 1587-1611, October.
- Marchetti, Domenico J. & Nucci, Francesco, 2006. "Pricing Behaviour and the Response of Hours to Productivity Shocks," CEPR Discussion Papers 5504, C.E.P.R. Discussion Papers.
- Thomas D. Willett, . "A Political Economy Analysis of the Maastricht and Stability Pact Fiscal Criteria," Claremont Colleges Working Papers 1999-33, Claremont Colleges.
- John C. Haltiwanger & Scott Schuh, 1999. "Gross job flows between plants and industries," New England Economic Review, Federal Reserve Bank of Boston, issue Mar, pages 41-64.
- David Neumark, 2000. "Changes in Job Stability and Job Security: A Collective Effort to Untangle, Reconcile, and Interpret the Evidence," NBER Working Papers 7472, National Bureau of Economic Research, Inc.
- Jamee K. Moudud, 2000. "Harrod versus Thirlwall: A Reassessment of Export-Led Growth," Macroeconomics 0012002, EconWPA.
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Published February 23, 2013, 12:00 AM
Photo gallery: Winter camping in the Boundary Waters
Amelia Evavold, 12, (left) and Emma Stattelman, 10, tow their toboggan across Brant Lake in the Boundary Waters Canoe Area Wilderness on Monday with moral support from Pip, Emma's dog. The two girls were part of a two-family winter camping trip in the BWCAW off the Gunflint Trail northwest of Grand Marais. (Sam Cook / email@example.com)


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Ran Zoom Quarry Lakes (Summer) in Fremont today, July 13th. Actually tried to run. Was in the first place up until I get to the point with orange and blue flagging at the same time (which means, instructions below, it's the right and the wrong path at the same time ). Turned back and that was it - the race was over for me (because I knew it cannot turn like this but where was it - that was a question). When I ran back to the finish (7 miles instead of 13.1) I knew it's all f&^% up, but the organizer's reaction was that it is my fault that I took a wrong turn - but I even didn't see any turns at the point where I ran back - and why should I guess about turns when I ran at 6:15 mpm??? Instead of organizing event in a right way (like adding a bicyclist to lead the way to leading group of runners) they/he just tried to make in a least affordable, for them, way - I think the whole team was like 10-12 people for 3 different distances. Anyway, totally screwed, idiotic, disorganized, fu*&$ up event. Will never do it again with this team and make sure other runners on different running forums know about that screw up...Btw, here are instructions from the site:The most important course marking is the polka-dot flagging. It indicates a turn at an intersection. There will be at least two polka-dot flagging before a turn in the course. The polka-dot flagging will be placed before and on the same side as the required turn. As you approach an intersection, look for any polka-dot flagging before the turn. Waiting until you're in the intersection to determine the correct direction may be confusing and you may go the wrong way. After you complete the turn, there will be yellow orange and/or pink flagging indicating the correct route. We also hang blue ribbons at critical junctions indicating the wrong way Blue is bad!...The funny thing is - I didn't see one polka-dot flagging, but we did a dozen of turns. Just total mess......If you don't see your respective flagging for 3-4 minutes, you are off course. If you get off course, you should retrace your path until you find where you left the course and then continue along the marked course.Man... If I am off course for 3-4 minutes, I am not interested in the course anymore - I was trying to run for a result, not for getting fun or chat with somebody - I can do it for free at any day on my training runs...
What a cluster****. Sorry to hear. However the silver lining is that you didn't trash yourself as if you had run a half, so you will be more fresh for your next week of training.
I would add the name of the race to the title of your thread - that will help dissuade people to run it.
Rebuilding r2th v3.0
R2TH - thanks for the suggestion (done). As not trashing myself - well, I even cut back on mileage this week to do my best in that race . The strange thing is that I was still not able to run anything faster than my MP speed. That becomes a bizarre issue for me - doesn't matter what distance I run - it's always around MP and it's always hard .
What's weird is that IIRC Hanson plan has some faster than MP workouts every week, so you should be used to run faster than MP at least for some distance. Are you able to do these workouts and how do you manage them?
Yeah, you are right - I run 10-15 secs faster than MP once a week, at least I am trying to . But this cycle it's kind of not so optimistic. Maybe because I am getting close to my max abilities, or maybe I am at max right now. So, your next FM is CIM? Or do you plan something different?
10-15s faster than MP is not that much faster - HMP is usually 25-30s faster. Maybe you're not targeting the correct paces? Do you use HR to guide your effort? Is it hot and does that mess up your paces?
Yes will target CIM for the next one. Will do a hill phase for the summer with a couple of hilly races and then a 12 week cycle.
10 secs faster than MP - that is what Hansons plan recommends for their strength workouts. Will see what happens later this year with my two planned marathons. Maybe it will make sense to switch to a different plan for the next year, the one which has more speed workouts.
Oh wow. I can't even understand the flagging directions as posted. I would have ended up in Stockton.
PRs | Marathon 3:28:20 | Half 1:35:47 | 10K 43:18 | 5K 20:25 | 2013 was a good year.
Upcoming: Presidio 10 (4/13) | Boston Marathon (4/21) | Run Through Redlands 5K (4/27) | Mammoth Half Marathon (6/22) | SeaWheeze Half Marathon (8/23) | NYC Marathon (11/2) | Run to Feed the Hungry 10K (11/27) | Probably some others, too.
I actually didn't understand them also when I was reading them. But two things happened which I didn't expect - first, I was pretty sure there will be some guidance (bicycle or people at turns) but there was none and second - I didn't expect I will be the guy leading the half marathon , so, I was not really ready to follow the flagging, I was hoping to follow other leading runners who know the route. And that the second task of navigating was not possible for an average guy like me .
Man, that sucks. I mean, really, how tough is it to have a bicyclist lead the way? I know plenty of folks who would be happy to lead a race.
The last 5K I did wasn't big--about 550 runners. We still had two motorcycle cops leading the way. (They missed a turn, but that's a different story.)
I agree with brdrski--I can't figure out the instructions as written.
Sorry about that experience calbearsfan. Zoom Running events just have never passed the sniff test. This just confirms it. They have a Quarry Lakes 5K/10K/HM/FM event coming up in December. How messed up is that one gonna be?!
800-2:29 1500-4:55 Mile-5:24 2Mile-11:36
5K-17:54 10K-37:24 1/2-1:22:48 Mar-2:54:07
My husband and I ran the 10K today at the same Zoom race, Quarry Lakes, Fremont, July 13. Well, more like we TRIED to run the race. We paid $75 (registration + $5 parking) for the privilege, and both of us had our races messed up due to the confusing layout of the run. I made a wrong turn so ended up with too short of a run, and my husband missed a turn and ended up running too far. We 'joked', inasmuch as we could afterward that at least we averaged 10K each.
When they gave the instructions at the beginning, I thought they were kidding. "Look for this color flag, not this, do this, and this"... I looked at people near me and we all started laughing at how complicated the 'instructions' at the start were.
By time I realized I had made a wrong turn, there was no way to fix it. It would have added 2 miles to my run to go back and rejoin the correct route. Other people approached around the time I realized my race was over and wrecked and said they had done the same thing as me. Some HAD turned around and gone back when they realized their mistake, if it was early enough. Some had said, forget it--too late to go back. So I can say definitely that at least 7 people doing the 10K got their times messed up. I only saw 10K finishers at this point when I was approaching the finish. Only after I finished did I find out from my husband that he ALSO got messed up and had a garbage result because he had missed a turn and run too far. When registration is $40 ($35 with no shirt), you kind of expect to get a route you can actually follow. I mean, if this were a free race, or you know, $10 even...MAYBE you could justify using just confusing flagging. But this wasn't a free race.
Never ever again.
Very odd. The operation in the Bay Area is clearly operating in an incompetant and unsafe manner. .I am always nervous with private for profit race operations. They can be good, but they can be just means of making money with less regard for safety. It is one thing for a race to be primarily driven by a charitable interest that hires a company to provide running services etc. But it is a very different beast to a race put on by a corporation (see below) soley for profit.
I did some basic research on Zoom. There are a few different but probbalyaffiliated entities. Zoom Multisport Racing Company looks like the parent. They have the same logo as Zoom Running Events. Here is how they describe themselves:
"Zoom Multisport Racing is a new family-owned company with over 20 years of combined race planning experience. We have sponsored, organized, directed and competed in hundreds of triathlon, duathlon, cycling, and running races across the U.S. and around the world."
They list Mick Mominee as the president of the company. But their website does not make it clear at all if they are corporation, LLC etc nor does it give a hard address.
The race you ran is clearly some affiliate of the same company as they are using the same "Z" shaped logo name and have similar stuff on their websites or they are using it with permission. But there is no effort on either site to preotect the trademark that I saw.
The website for Zoom Running Events has an address:
Zoom Running Events
322 El Paseo Cir
Walnut Creek CA 94597
The google maps for that address shows empty lots in the satelite photo and it says the imagery is from 2013. All in all I suspect this is some attempt to make some money without doing all the things one is supposed to or should be doing.
Zoom Running Events is listed as a corporation registered at that same address. The agent of service is also at the address. He is WENDELL J. DOMAN
What actual city was the race that you ran in? Or was it in the unicorporated county. They should have had to have drawn a permit etc. Did the race benefit anyone or any org or was it just a race to make profits for the corporation?Their website makes it seem like a shoestring operation. For instance, they ask for volunteers to work tables in exchange for discounted or free registration. There is also nothing interms of mission, gudielines etc. In that sense there is a lot of contrast with the Zoom Multisport Racing website which is better (but still weak).
The race was in Fremont. I don't think they had any charity mission involved. Also they didn't warn anybody that you have to pay $5 when you enter the park where they had an event. Usually other companies mention that on their web site. As I said already, when I mentioned having a guiding bicyclist to the "main" guy, he laughed to my face. Total morons...
I couldn't help but chime in here. Let me be clear. I am not an elite runner; far from it. I am in my early 50's and started running a year ago. I average about a 9:30 mile in half marathons. Yesterday's run in Fremont was my 5th half marathon in the past 7 months. I really enjoy runnIng the 1/2. This Zoom event yesterday was the second Zoom event I have done. I also ran the San Francisco Half a month ago. So my point is I have a few other races to compare to.
The first Zoom event I ran was the one in Palo Alto in December, about 7 months ago, my first 1/2 marathon ever. It was a great course and I'd like to do it again this year. The only complaint I had at that event was that there weren't enough aid stations. There was a long stretch in there without water and my only complaint about Zoom at that event.
On to yesterday's event in Fremont. I'd have to be blunt and say that it was a complete joke as far as directions go. I am one of the runners who got lost. There were others running along side of me who did the same.
Long story short, I ended up running my own race, time my own pace and ended up mapping out my own distance to finish a 13.1 mile run. Well, put it this way, I could have done that around my neighborhood and where I normally do my training run. Why even bother paying to do a race?
The problem stems from the fact that there wasn't anybody at some of these forks/turns to direct runners to the proper course/path. That or there needed to be clear, big signs to direct the runners to the proper direction, 5K, 10K or 1/2. There were a few places where a bunch of us were scratching our heads and needless to say, many of us made the wrong turns at some point, somewhere.
In short, the streamers were totally inadequate. Surely, one of the volunteers stated in the beginning of the race about what the colors meant, etc., but frankly, I didn't remember what he said or which color was what after I got going. At any rate, these streamers only added to the confusion as there weren't enough, poorly placed, and/or not clear where they counted
I am willing to give a Zoom event another try but I would advise the organizers to make sure 1) there are enough aid stations (Palo Alto in December of 2012) and 2) ensure there are enough volunteers and/or clearly marked signs to direct runners at turns or forks on the course.
I hope Zoom will take note of these inputs and make the necessary changes in the future.
Thank you & happy trails.
I am very sorry to hear you had a negative experience with this race and company. I am the owner of Zoom Multisport Racing, LLC out of Dayton Ohio and we are found on the web at zoomracingusa.com. I noticed that someone linked our company to this event in one of the replies. I wanted to note that we host our races in Ohio and were not associated with this race. We make every effort to ensure that we have accurate timing, a clearly marker course, and an overall great experience. In fact, we double and triple mark the course with signs, chalk and volunteers. As a racer, I know what it is like to go off course, and it is even more frustrating when it is the organizers fault. I want to be able to get into my zone and I assume that the course will be clear so I do not have to hesitate. When I pay money for a race, I want a professional, safe, and fun experience. I hope that others do not confuse our company with these races and if you ever visit Ohio, I would welcome you to join us for a triathlon, duathlon, or running race.


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Terms of Use | Privacy Policy Subscribe to O, The Oprah Magazine |
Photo: Neilson Barnard/Getty 'Tis the season? Yes, it is— but Donna Brazile would like to mention a few other occasions ripe for gift giving:
1. When an out-of-town guest asks to stay with you
Perfect time to deliver a hotel voucher. If you have the means, the luxury of a little space allows you to enjoy each other's company even more. 2. The anniversary of the death of a parent Losing family hurts like nothing else. Sending your friend a little something lets her know you're thinking about her on a difficult day. 3. Always-a-Bridesmaid Day I've spent thousands on showers, weddings, babies—and for the record, I'm happy to do it—but sometimes it feels as if the world is built for couples. A small token for those of us who never married or had children? That's nice. 4. Lifelong-Friends Day Okay, this is another holiday that doesn't actually exist, but I think it should, so how about we start it together? Where to Shop: Discover hundreds of perfect presents with the Oprah.com Gift Finder More Advice from Donna Brazile From the December 2010 issue of O, The Oprah Magazine
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Did you know that you can earn even more miles with a SWISS Miles &More credit card?
The ValuePack offers holders of SWISS Miles & More credit cards with activated ValuePack more benefits and services.
Benefit from an annual flight voucher, worth as much as your annual membership fee (max. CHF 300). Off-setting: SWISS issues vouchers in the form of bonuses. When you purchase a SWISS flight ticket at SWISS.COM (regardless of flight category and costing a minimum of CHF 999), we will reduce the total amount by the value of your annual membership fee (max. CHF 300). All you have to do is settle the remaining amount with your SWISS Miles & More credit cards. You will receive your voucher automatically once a year after paying your annual membership fee.
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Seating is Limited
RSVP by April 26th, 2013
Call 518-442-5373 or email
University at Albany donors provide vital support to students and faculty in their scholarly endeavors, and enrich the educational and research initiatives for which UAlbany is so well known.
To support the Hogarty Family Foundation Lectureship Fund visit www.albany.edu/giving.
Thank you for your support!
Hogarty Family Foundation Lecture
Established through the generosity of Daniel J. Hogarty and the Hogarty Family Foundation, an endowed fund provides support for a public lecture program through the University at Albany's Cancer Research Center. The Hogarty Family Foundation Lectures provide information to the community about a broad range of topics related to cancer, cancer genomics and cancer research.
The topic of the fourth annual lecture is:
How understanding the causes of breast and prostate cancer leads to new drug discoveries
Donald P. McDonnell, Ph.D.
Glaxo-Wellcome Professor of Molecular Cancer Biology
Chairman, Department of Pharmacology and Cancer Biology
Duke University School of Medicine
Wednesday, May 1st, 2013
There will be a reception at 5:15 pm in the School of Public Health Atrium.
The lecture will begin at 6 pm in the School of Public Health Auditorium.
George Education Center Auditorium
School of Public Health
East Campus
University at Albany
1 University Place
Rensselaer, NY 12144
For directions, please visit the University's directions page or get turn-by-turn directions from Google Maps
Support provided in part by
About the Speaker
Donald P. McDonnell, PhD, is the Glaxo-WellcomeProfessor of Molecular Cancer Biology and Chairman of the Department of Pharmacology and Cancer Biology at Duke University School of Medicine. In addition, he serves as the Associate Director for Basic Research for the breast, ovarian and prostate programs within the Duke Cancer Institute.
Dr. McDonnell obtained his undergraduate degree in Biochemistry from the National University of Ireland (Galway) in 1983. He then moved to Baylor College of Medicine, Houston, Texas, where in 1987, he obtained a PhD under the mentorship of Dr. Bert O´Malley. It was during this time that he cloned the cDNA for the vitamin D receptor and performed a series of experiments that led to the conclusion that this receptor was related in both sequence and function to the classical steroid receptors. He subsequently spent a year as a postdoctoral fellow at Smith-Kline Pharmaceuticals in Philadelphia where he developed an interest in studying the molecular pharmacology of nuclear receptors. He was appointed Assistant Professor in Cell Biology at Baylor College of Medicine, but in 1991 he returned to the private sector as Director and Head of Molecular Biology at Ligand Pharmaceuticals in San Diego. After three very exciting years in industry, he moved to Duke where his work has focused on the genetic and pharmacological dissection of the nuclear receptor signal transduction pathways. The insights from this work have led to the discovery and development of novel estrogen and androgen receptor modulators, some of which have advanced to the clinic and are being evaluated as treatments for a variety of endocrine disorders.
Dr. McDonnell has received the Ernst Oppenheimer Award from the Endocrine Society, the John J. Abel Award from ASPET, the Pharmacia-ASPET Award for Experimental Therapeutics and the NAMS/Eli Lilly and Company SERM Research Award. He was also elected to join the Council of the Endocrine Society. He is an Honorary Fellow of the Royal College of Physicians, Ireland. Dr. McDonnell has published over 225 articles on the molecular pharmacology of nuclear hormone receptors. Currently, he sits on the editorial boards of Oncogene, Trends in Endocrinology and Metabolism and Molecular Endocrinology.


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Install Android 2.2 Froyo on your jailbroken iPhone 3G over-the-air with Bootlace
Get your Android on by adding the repository "http://repo.neonkoala.co.uk'" to Cydia, and jump on over to Redmond Pie for their blow-by-blow guide.
Switched has a new home! Huffpost Tech.
Click here to visit the new home of Switched!Yeah, I saw it'll work, but the latest info I've seen was back from June and said that wifi and sound don't work in Android. Well 5 months later you'd expect those issues were hashed out, but I don't see anything outlining what to expect when running Android on the 3G regarding hardware compatibility.
"Funny how the jailbreak community has made the process of installing Froyo on an iPhone easier than updating many Android phones."
You mean, except for the part where you have to jailbreak your iPhone and install Cydia first? Once you've rooted an Android phone, ROM Manager is both free and pretty darn simple to use.
Now, rooting Android itself ranges from stupidly easy (Univeral Androot, SuperOneClick, Unrevoked) to "be careful you don't brick your phone" (the 2-hour old as of this comment perma-root & s-off solution for the HTC Vision/G2).
And on the n900, install rootsh and nitdroid packages from the extras-devel repository, just click the package and it installs. Open up terminal, type "sudo gainroot" to get root and then type "nitdroid" to open up the installer. Type "YES" to confirm installation, and it automatically formats your microsd card and installs froyo, multiboot, etc. No hassle. :)
Just a little note, but this should be working on new iOS devices sometime soon as well. For this to work requires a bootrom exploit which has been unavailable for iPhone3GS and later, but I just read that a new bootrom that works on all iOS devices capable of running iOS4 has been confirmed so I'm guessing we will see it available in a couple months.
Well, it appears that there's some attempt to get this onto the 3GS, at least according to this http://www.idroidproject.org/wiki/Status
I hope that it happens.
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#include <db_cxx.h> int DbEnv::txn_stat(DB_TXN_STAT **statp, u_int32_t flags);
The DbEnv::txn_stat()
method returns the transaction subsystem
The DbEnv::txn_stat()
method creates a statistical structure of type
and copies a pointer to it into a user-specified memory
Statistical structures are stored in allocated memory. If application-specific allocation routines have been declared (see DbEnv::set_alloc() for more information), they are used to allocate the memory; otherwise, the standard C library malloc(3) is used. The caller is responsible for deallocating the memory. To deallocate the memory, free the memory reference; references inside the returned memory need not be individually freed.
The following DB_TXN_STAT fields will be filled in:
u_int32_t st_inittxns;
The initial number of transactions configured.
DB_LSN st_last_ckp;
The LSN of the last checkpoint.
u_int32_t st_last_txnid;
The last transaction ID allocated.
u_int32_t st_maxnactive;
The maximum number of active transactions at any one time.
u_int32_t st_maxnsnapshot;
The maximum number of transactions on the snapshot list at any one time.
u_int32_t st_maxtxns;
The maximum number of active transactions configured.
uintmax_t st_naborts;
The number of transactions that have aborted.
u_int32_t st_nactive;
The number of transactions that are currently active.
uintmax_t st_nbegins;
The number of transactions that have begun.
uintmax_t st_ncommits;
The number of transactions that have committed.
u_int32_t st_nrestores;
The number of transactions that have been restored.
u_int32_t st_nsnapshot;
The number of transactions on the snapshot list. These are transactions which modified a database opened with DB_MULTIVERSION, and which have committed or aborted, but the copies of pages they created are still in the cache.
uintmax_t st_region_nowait;
The number of times that a thread of control was able to obtain the transaction region mutex without waiting.
uintmax_t st_region_wait;
The number of times that a thread of control was forced to wait before obtaining the transaction region mutex.
roff_t st_regsize;
The region size, in bytes.
time_t st_time_ckp;
The time the last completed checkpoint finished (as the number of seconds since the Epoch, returned by the IEEE/ANSI Std 1003.1 (POSIX) time function).
DB_TXN_ACTIVE *st_txnarray;
A pointer to an array of st_nactive DB_TXN_ACTIVE structures, describing the currently active transactions. The following fields of the DB_TXN_ACTIVE structure will be filled in:
u_int32_t txnid;
The transaction ID of the transaction.
u_int32_t parentid;
The transaction ID of the parent transaction (or 0, if no parent).
pid_t pid;
The process ID of the originator of the transaction.
db_threadid_t tid;
The thread of control ID of the originator of the transaction.
DB_LSN lsn;
The current log sequence number when the transaction was begun.
DB_LSN read_lsn;
The log sequence number of reads for snapshot transactions.
u_int32_t mvcc_ref;
The number of buffer copies created by this transaction that remain in cache.
u_int32_t priority;
This transaction's deadlock resolution priority.
u_int32_t status;
Provides one of the following constants, indicating the transaction status:
u_int32_t xa_status;
Provides one of the following constants, which indicate the XA status:
u_int8_t gid[DB_GID_SIZE];
If the transaction was prepared using DbTxn::prepare(), then gid contains the transaction's Global ID. Otherwise, gid's contents are undefined.
char name[];
If a name was specified for the transaction, up to the first 50 bytes of that name, followed by a nul termination byte.
The DbEnv::txn_stat()
method may not be called before the
DbEnv::open() method is called.
The DbEnv::txn_stat()
method either returns a non-zero error value or throws an
exception that encapsulates a non-zero error value on
failure, and returns 0 on success.
The statp parameter references memory into which a pointer to the allocated statistics structure is copied.
The DbEnv::txn_stat()
method may fail and throw a DbException
exception, encapsulating one of the following non-zero errors, or return one
of the following non-zero errors:


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For the engine to properly power up the wheels of your car, it has to have a top-notch Jeep Cherokee spark plug. Without your auto's spark plugs, how else can your engine be able to utilize the fuel that is delivered to it? If you have any wearing spark plug, it's best to have change that component right away with a durable and top-performing one.
Your engine requires these elements in order move your ride: fuel, air, and spark. For fuel to ignite, your car's spark plugs should be able to fire electric sparks at precise timings. The engine's performance will absolutely dip if the spark plugs are not functioning well. What you should be worried about are the costs of repairing or replacing the engine parts that are affected if the sparks is malfunctioning. The good news is, Parts Train, on its shelves, has the perfect spark plugs just for you.
The first-rate spark plugs that you need is just a few clicks away at Parts Train. These components are guaranteed to do their job well for a long time simple because our suppliers put warranty on the products they manufacture. Roush, Bosch, and Omix are the main suppliers of our store's first-class spark plugs. Search your Jeep Cherokee spark plug by putting your vehicle's information in our search bars.
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United States Senate special election in Pennsylvania, 1991
County results | ||||||||||||||||||||||
The 1991 United States Senate Special election in Pennsylvania was held on November 5, 1991. Incumbent Democratic U.S. Senator Harris Wofford won the special election that was held because of the death of Republican Senator John Heinz on April 4 of that year. Wofford was appointed by Governor Bob Casey to serve as Senator until the special election which he subsequently won. Major-party candidates for this election were chosen by party committees, as the vacancy had happened too late for a primary to be held.
Major candidates[edit]
- Harris Wofford, incumbent U.S. Senator and former State Secretary of Labor
- Dick Thornburgh, former Governor and U.S. Attorney General
Wofford's win was impressive because as little as 5 months before the election, polling showed him to be trailing Thornburgh by upwards of 40 points. Both the state and national Democratic establishment was tepid toward Wofford's campaign, feeling that Governor Casey had missed a prime opportunity to select a top tier candidate and had instead created a situation where Republicans would take back the seat just months after losing it. In conjunction with his fundraising issues, Wofford also had difficulty communicating his message to the voters; because he had a bureaucratic as opposed to a political background, he spoke in a somewhat long-winded manner that received criticism in the media. With his large lead in the polls, Thornburgh laid back to avoid mistakes, which allowed Wofford to gain traction. Despite his elite upbringing, Wofford connected well with working class voters as he made access to healthcare a huge plank of his campaign. He also successfully derided Thornburgh for his connections to the president, as Bush's popularity was steeply declining due to a recession.[1]
Thornburgh was unable to mount credible attacks against Wofford until after the Democrat had already established himself. As a result, Wofford was not only victorious in traditionally Democratic areas, such as Philadelphia city, Scranton, and metro Pittsburgh, but he also ran well in GOP strongholds. Wofford won three of the four suburban Philadelphia counties, which, although socially liberal, were strongly aligned with Republicans; the "roll-up-your-sleves" style campaign ran by Wofford also allowed him to perform stronger than most Democrats in rural regions and to even win several usually Republican counties with a strong labor base.[1]
Pennsylvania United States Senate Election, 1991 (Special) | |||||
Party | Candidate | Votes | % | ±% | |
Democratic | Harris Wofford (Incumbent) | 1,860,760 | 55.01 | ||
Republican | Dick Thornburgh | 1,521,986 | 44.99 | ||
Majority | 338,774 | 10.01 | |||
Turnout | 3,382,746 | ||||
Democratic hold | Swing |
- ^ a b Kennedy, John J. (2006). Pennsylvania elections : statewide contests from 1950-2004. Lanham, Md.: University Press of America. pp. 68—70. ISBN 0761832793.


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Great Gifts On A Budget: Ghetto Baskets
Ghetto Baskets are gift baskets packed chock-full of stuff you can buy at your local convenience store. The standard Ghetto Basket costs $39, and the Ghetto Fabulous basket $46 (comes with a bow).
You never know exactly what each Ghetto Basket will include. It all depends on our shaky contacts and what falls off of trucks around the neighborhood. But it might have:
Hot Sauce, Pregnancy Test, Grape Drink, Batteries, Beef Jerky, Potted Meay, Pork Rinds, Noodles in a Cup, After Shave, Plastic Commemorative Plate, Religious Candle, Porcelain Figurine, Kung-Fu DVD, Cassette or VHS Tape, Doo Rag, Vapor Rub, Energy Drank, Soap, Outdated Calendar
Each basket comes lovingly packed in an aluminum baking pan and is sure to do disappoint its recipient. Alternatively, assemble your own basket for $14 and just tell the giftee you paid $40 at a novelty website. Now that's ghetto!
Thanks samual and chris, your pregnancy tests are in the mail. And no, I didn't already use them (of course I did).
I've been looking for something to tie my living room together and I think this might just be the thing: a 145-lb skull carved out of a solid piece of flourite. Did you hear that, George Lucas? YOUR CRYSTAL SKULL WAS A TURD COMPARED TO THIS ONE! Plus the rainbow beauty sold ... / Continue →
Blik Re-Stik Asteroid Wall Decals are $45 sticker packs that turn your frown upside down wall into a giant unplayable game of Asteroids. That's a whole set pictured, so you can get an idea of what you could do with one. Which, whether you have any sense of composition or not,... / Continue →
Anybody seen my Power Glove? I can't perform without my Power Glove on. Whew, found it. Now -- I want you to pretend like I'm a game cartridge that won't play. Two more shots of the "wait -- where are you going?!" after the jump.... / Continue →


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Browse Results
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The Wyoming Kid (Wyoming #2)
by Debbie MacomberRancher Lonny Ellison has never known a woman like Joy Fuller. For one thing, she doesn't seem very interested in him, and as a former rodeo cowboy, Lonny's not used to that. Women mobbed the Wyoming Kid during his rodeo days! And another thing. He and Joy - who's a schoolteacher and his sister Letty's best friend - seem to argue constantly. But it doesn't matter, does it? Because he's not interested in Joy, either. Wait a minute. Maybe he is. At least, that's what Letty seems to think their arguments are all about. Yup, she might have a point there. Now he has to convince Joy that marriage to the Wyoming Kid will be as exciting as an eight-second bull ride and as sweet as the cookies she loves to bake.
Yours and Mine
by Debbie Macomberwww.DebbieMacomber.comCan they get it right the second time? Single mom Joanna Parsons insists that marriage is an experience she doesn't plan to repeat, no matter what her eleven-year-old daughter, Kristen, thinks. Tanner Lund feels the same way. Like Joanna, he got divorced after a short, disastrous marriage. And like her, he's raising his eleven-year-old daughter, Nicole, alone. But Kristen and Nicole have other plans in mind-and it involves the best friends becoming sisters. Both Tanner and Joanna are determined to resist marriage, but have they underestimated their daughters?
Getting a Ph.D. in Economics
by Stuart J. HillmonConsidering a graduate degree in economics? Good choice: the twenty-first-century financial crisis and recession have underscored the relevance of experts who know how the economy works, should work, and could work. However, Ph.D. programs in economics are extremely competitive, with a high rate of attrition and a median time of seven years to completion. Also, economic professions come in many shapes and sizes, and while a doctoral degree is crucial training for some, it is less beneficial for others. How do you know whether a Ph.D. in economics is for you? How do you choose the right program--and how do you get the right program to choose you? And once you've survived years of rigorous and specialized training, how do you turn your degree into a lifelong career and meaningful vocation?Getting a Ph.D. in Economics is the first manual designed to meet the specific needs of aspiring and matriculating graduate students of economics. With the perspective of a veteran, Stuart J. Hillmon walks the reader though the entire experience--from the Ph.D. admissions process to arduous first-year coursework and qualifying exams to armoring up for the volatile job market. Hillmon identifies the pitfalls at each stage and offers no-holds-barred advice on how to navigate them. Honest, hard-hitting, and at times hilarious, this insider insight will equip students and prospective students with the tools to make the most of their graduate experience and to give them an edge in an increasingly competitive field.
The Other Kind of Smart
by Harvey DeutschendorfWe have known for years that the difference between those who become successful in life and those who struggle is their degree of emotional intelligence (EI), or "people skills." Now, The Other Kind of Smart shows readers how they can increase their emotional intelligence and overcome the barriers that are preventing them from realizing their true potential. Emotional intelligence coach Harvey Deutschendorf has shown thousands of people how to relate emotional intelligence to everyday situations. Here, he uses the proven techniques of storytelling, combined with quotes and exercises, to show readers how to apply the principles of EI on the job. Filled with real-life scenarios and solutions, the book offers tools that will bring results in as little as five minutes a day and shows how to develop stress tolerance, cultivate empathy, increase flexibility with co-workers, boost assertiveness, and resolve problems successfully. Complete with an EI quiz that will help readers measure their own level of emotional intelligence, this invaluable guide will enable everyone to improve their relationships and increase their effectiveness at work in a practical, accessible way.
by Diana PalmerPenelope Mathews had spent her entire adolescence worshipping the elusive C. C. Tremayne-from afar. Until one night, trying to protect the mysterious loner from landing in a Mexican jail after he had drunk a little too much, Pepi was forced to seek refuge in a wedding chapel-and wound up going one step further by emerging as Mrs. Connal Cade Tremayne!When C.C. realized what had happened, he was outraged-the last thing he needed was a shy virgin on his hands. The marriage was off; he'd see to an annulment immediately. Yet the more time he spent with Pepi, the more he realized he didn't want a divorce... he wanted forever.
by Diana PalmerEver since she could remember, Anna Cochran had been passionately, shamelessly in love with tall, quiet Evan Tremayne. But the stubborn man was so focused on protecting her from rough-and-tumble cowboys like him that he wouldn't acknowledge the fierce yearning she awoke in him.So it was up to Anna to draw Evan out of his shell and prove that she was the only woman for him now...and always.
Sutton's Way
by Diana PalmerWyoming rancher and single father Quinn Sutton is raising a child he knows isn't his own. All the love left in his guarded heart goes to the boy. But when a beautiful city woman is stranded nearby in a blizzard, he rescues her and brings her to Ricochet Ranch.Amanda Callaway has her own secrets and plans to keep her distance. If only she weren't falling for her unlikely hero...
by Diana PalmerWith only a quick glance at Nell Regan, a man might miss the beauty in the shy face, or the sexy figure hidden beneath the shapeless clothes. Nell had learned the hard way that she had nothing to offer a man. Her future was here, running her Arizona dude ranch...alone.Then Tyler Jacobs arrived...a man who knew what it was like to be alone and alienated. He yearned to kiss away the pain he saw in Nell's deep brown eyes.But Nell wasn't about to mistake kindness for love. Not again. Yet would denying her own desire destroy her one chance for happiness?
by Diana PalmerSweet dreams had been all that lovely Shelby Jacobs had ever given Justin Ballenger. He'd loved her, wanted to marry her...and his sweet dreams had blown away. A Ballenger wasn't good enough for Shelby...she'd broken their engagement and flaunted her rich society lover in Justin's face. He vowed never again to be vulnerable to his beautiful Texas rose.Shelby had never stopped loving dark, intense Justin, and seeing him only deepened her feelings. She was sure he despised her, but she knew he needed to hear the truth about the past. She was risking everything, but the heart of her lonesome cowboy was more than worth it...
by Diana PalmerLONG, TALL...AND BLIND?Abby Clark was sick of being treated like a child. Sure, she may have been just a girl when she came to live with Calhoun Ballenger and his brother, but she had long since grown up and it was time Calhoun realized it. So she devised a plan to prove her independence-and capture his attention.But Abby's scheme backfired. She was far from the worldly women Calhoun usually spent time with, and his protective streak only seemed to intensify. How could she make him acknowledge his feelings for her without getting burned in the process?
An Heir of Uncertainty
by Alyssa EverettYorkshire, 1820Lina, Lady Radbourne, thought being a countess would rescue her from poverty. Unfortunately, her young groom failed to plan for the future, and his drunken accident left her widowed and pregnant. Now Colonel Winstead Vaughan-Win-will inherit her late husband's fortune...unless she gives birth to a boy. Win is her natural enemy, so why can't she stop thinking about him?Win is stunned to learn he stands to inherit a vast fortune. He's even more surprised to find himself falling for the beautiful, spirited Lady Radbourne, who is the one woman who stands in the way of a life he'd only imagined.When someone tries to poison Lady Radbourne, suspicion falls on Win. There's a clever killer in their midst, and if Win doesn't solve the mystery fast, Lina may perish. He needs to win her trust, but how can he prove it's she he wants, and not the fortune?86,000 words
Helmut Saves the World
by Matt SheehanMy name is Helmut Haase and I'm one half of the Fog City Detective Agency-specifically, the half that pays all the bills. My partner, Shamus O'Sheehan, mostly drinks beer and naps. I keep him around because he's my friend, but also because he's a Druid. I'm just a detective, and there are plenty of those in Wudong, the Confederacy of Hesperia. There's not another Druid for miles.We had it pretty good until the day we met Alek Pallas. He hired us to track down a thieving employee, and even though something was off, his big fat check was too much to pass up. But the man we found wasn't what we were led to believe, and neither was Alek.I'm talking shape-shifters, fallen angels and a conspiracy involving the vicious Cretan Empire. At least we didn't die. Hope that doesn't ruin the story.Why am I telling you all this? Someday I'd like some credit for saving the world. Maybe not the entire world, and maybe not alone, but I still deserve a medal. And perhaps a cash prize.31,000 words
Hangzhou Lectures on Eigenfunctions of the Laplacian
by Christopher D. SoggeBased on lectures given at Zhejiang University in Hangzhou, China, and Johns Hopkins University, this book introduces eigenfunctions on Riemannian manifolds. Christopher Sogge gives a proof of the sharp Weyl formula for the distribution of eigenvalues of Laplace-Beltrami operators, as well as an improved version of the Weyl formula, the Duistermaat-Guillemin theorem under natural assumptions on the geodesic flow. Sogge shows that there is quantum ergodicity of eigenfunctions if the geodesic flow is ergodic.Sogge begins with a treatment of the Hadamard parametrix before proving the first main result, the sharp Weyl formula. He avoids the use of Tauberian estimates and instead relies on sup-norm estimates for eigenfunctions. The author also gives a rapid introduction to the stationary phase and the basics of the theory of pseudodifferential operators and microlocal analysis. These are used to prove the Duistermaat-Guillemin theorem. Turning to the related topic of quantum ergodicity, Sogge demonstrates that if the long-term geodesic flow is uniformly distributed, most eigenfunctions exhibit a similar behavior, in the sense that their mass becomes equidistributed as their frequencies go to infinity.
Deepening Community
by Paul BornCommunity shapes our identity, quenches our thirst for belonging, and bolsters our physical, mental, emotional, and economic health. But in the chaos of modern life, community ties have become unraveled, leaving many feeling afraid or alone in the crowd, grasping at shallow substitutes for true community. In this thoughtful and moving book, Paul Born describes the four pillars of deep community: sharing our stories, taking the time to enjoy one another, taking care of one another, and working together for a better world. To show the role each of these plays, he shares his own stories--as a child of refugees and as a longtime community activist. It's up to us to create community. Born shows that the opportunity is right in front of us if we have the courage and conviction to pursue it.
Making Sustainability Work
by Marc J. Epstein Adriana Rejc BuhovacNEW EDITION, REVISED AND UPDATED Most companies today have some commitment to corporate social responsibility, but implementing these initiatives can be particularly challenging. While a lot has been written on ethical and strategic factors, there is still a dearth of information on the practical nuts and bolts. And whereas with most other organizational initiatives the sole objective is improved financial performance, sustainability broadens the focus to include social and environmental performance, which is much more difficult to measure. Now updated throughout with new examples and new research, this is a complete guide to implementing and measuring the effectiveness of sustainability initiatives. It draws on Marc Epstein's and new coauthor Adriana Rejc Buhovac's solid academic foundation and extensive consulting work and includes best practices from dozens of companies in Europe, Asia, North America, South America, Australia, and Africa. This is the ultimate how-to guide for corporate leaders, strategists, academics, sustainability consultants, and anyone else with an interest in actually putting sustainability ideas into practice and making sure they accomplish their goals.
Unleashed: Dog's Eye View of Life With Humans
by Brad PattisonDog advocate and human-being life coach Brad Pattison brings his innovative, tough-love training and in-your-face counselling skills to the page. Whether you're just getting started on training your new pup, looking to take your good relationship with your dog to a higher level, or trying to correct negative dog behaviours, Brad Pattison's book will provide DIY training material that underlines how you can teach your dog to be a healthy, happy member of your family. Each chapter focuses on a different aspect of Pattison's established training techniques, anchored by real-life success stories and focus dogs. Examples of chapter titles: Dog Speak: Harnessing Canine Communication Methods to Enhance Interspecies Relations; Coddled Canines: The Dangers of Heavy Petting and the Best Methods for Rewarding Your Dog; and Co-Evolution: Raising the Bar and Strengthening the Bond. From the Hardcover edition.
A Spell is Cast
by Eleanor CameronWhen her adoptive mother sends her to visit her Uncle Dirk and grandmother at their great house beside the pacific ocean, Cory Winterslow finds mystery--strange music in the night, whispers of the people of the town, and rumors about her own unicorn necklace.
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Super Bowl XLVII on CBS: The Good, Bad & Ugly
Good, bad, and ugly posts tend to naturally force writers to give the negative more coverage than the positive. Had NBC broadcast Super Bowl XLVII, that might have made things tough on me. But with CBS in charge and a 34-minute power outage in the mix, it was easy to find enough problems to fill the "bad" and "ugly" columns. This was not a smooth broadcast, but I did notice some non-terrible things, too, and I'll kick off the recap with those.
The Good
* The introduction featuring Joe Namath, Don Shula, Marcus Allen and other Super Bowl legends was pretty sick. I liked the CBS intro with Jay-Z and Rihanna three years ago, and they stuck with a classical remix this time, using Queen's "We Will Rock You." It was tasteful, well-produced and not too cheesy.
* I focused mainly on the game, but Boomer Esiason went in on Ray Lewis late in the pre-game and it was the best thing that came out of a CBS broadcaster's mouth the entire day or night. It's too bad Boomer had to jump over to the radio side and we never heard from him the rest of the night on CBS. Boomer's final comment on the CBS airwaves Sunday night: "This is not Ray Lewis' personal Super Bowl." Nice.
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The Mariemont Board of Education announced the selection of the district's new superintendent.
Steven Estepp will be formally appointed to the position at a board meeting on April 23 at Mariemont Elementary School.
The district's former superintendent, Paul Imhoff, accepted an offer to serve as superintendent of the Upper Arlington City School district, a suburb of Columbus, beginning the 2013-14 academic year.
Estepp comes from the Hilliard City School district, having served as the executive director of K-12 curriculum & instruction.
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Home » Undergraduate College » Admission » Art & Music » Courses
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Intro to Photo & Digital Lab
4 sem. hrs. Teaches the art and craft of contemporary color photography with emphasis on using the medium as a means of personal expression. Hands on demonstration demystify how manual and digital cameras work, Students learn effective Photoshop and Camera Raw to produce color prints with impact.
Course details
- Course number: COMM-139
- Credits: 4.00
- Academic Level: Undergraduate
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Apr 02
I am hoping for the #6,7,8 spot
Any match up is a good match up... just need to show up and give it all we got.
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A.Word.A.Day |
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Discuss A.Word.A.Day--moietyThis week's theme: miscellaneous words. moiety (MOI-i-tee) noun 1. A half. 2. A portion. [From Latin medius (middle). Ultimately from the Indo-European root medhyo- (middle) that's also the source of middle, mean, medium, medal (originally a coin worth a halfpenny), mezzanine, and mediocre.] See more usage examples of moiety in Vocabulary.com's dictionary. -Anu Garg (words at wordsmith.org) "Amazingly, Carbery failed to score in the opening moiety." Ballincollig Impress; The Southern Star (Skibbereen, Ireland); Jun 16, 2007. X-BonusIf there existed no external means for dimming their consciences, one-half of the men would at once shoot themselves, because to live contrary to one's reason is a most intolerable state, and all men of our time are in such a state. -Leo Tolstoy, novelist and philosopher (1828-1910) |
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Lawrence Gaydeski service set for Saturday, Dec. 8
Published on Fri, Nov 23, 2012 by
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A potluck memorial service for Lawrence Gaydeski is scheduled for the Old Mill Roundhouse at 110 Business Park on Saturday, Dec. 8 beginning at 1 p.m.
Gaydeski passed away on Sunday, Nov. 18 from complications related to diabetes.
Gaydeski served three terms as the West End's Clallam County Commissioner, beginning in 1982.
The Gaydeski family's homestead is located north of Forks along the Sol Duc River. The family arrived in the West End in the early 1900s and first settled at a site known as the Polish Settlement, near the Dickey River. The settlement was named for its founders the Gaydeski and Warminski and other Polish families who had moved from Nebraska in the late 1800s.
After about five years later the Gaydeski family moved to their homestead at Shuwah, along the Sol Duc River. The family homestead is located today along Gaydeski Road where family members live on subdivided sections of the original homestead.
Lawrence's memorial service will be led by his life-long friend Merle Watson. The two grew up together and served as class officers for the Forks High School Class of 1948. Lawrence worked as a logger for three decades and operated a cedar shake mill with Cliff Thayer.
Lawrence is survived by his wife Dixie, who was his sweetheart during their years at Forks High School. He was born in Sappho on Nov. 11, 1930 to Stephen and Louise Gaydeski. The couple raised six children.
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Justin Timberlake's "Mirrors" is a lengthy love song about reigniting a flame that you should have never let burn out in the first place. I had previously mentioned that I have some reservations about how this comeback album will sound and it's very clear that a lot of the material Timberlake will be releasing is inspired by his marriage to Mary Camden Jessica Biel. Sometimes wedded bliss makes performers boring — see Usher's Here I Stand — but "Mirrors," however, puts me at ease. When you hit the halfway mark, the track materializes into the multi-layered space pop we've come to expect from JT and Timbaland. While a lot of these layers are Timberlake repeating "You are the love of my life," the innovation negates the saccharine — or maybe I am just becoming a sap. All up for debate. I do think this song begs for a remix from Future. Just putting that out there, Universe. Check out "Mirrors" below.
The 20/20 Experience is out 3/19 on RCA.
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The big blue bins have brought recycling ease to Tulsa and a financial squeeze to the MET.
"We're going to lose about $100,000 in revenue by having less recyclables to sell and put into the market place," said MET director Michael Patton.
And that translates into tough times ahead for some of the 60 developmentally challenged adults who currently work at one of Tulsa's five recycling drop off centers.
"We probably have to close some centers, so the five in Tulsa, we don't think we'll have five, we don't think we need five so maybe three super centers or four is a better option for us," he said.
"It's slow, and Saturday's not usually a slow day," said Tom Harrell. He used to work at the MET but left for another job, and says his friends have noticed the drop off in business. As for folks who might soon be out of a work, Karie Jordan helps employers see the advantages of hiring someone with various challenges.
"It's not the barriers it's the capabilities that they have and not the disabilities that they have," she said.
Tom, for example, has become a go-to guy at Pepsi.
"Some of the people that work at Pepsi come to me and ask questions, and that gives me a good feeling too," he said.
Meanwhile, folks still in recycling are on a conveyor belt towards change.
"Nothing going to happen until after the first of the year, but come spring their might be some dramatic changes," said Patton.
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Coweta marked one of its darkest days Monday night, as a circle of candles illuminated messages from friends and classmates left to remember a 9th grader who ended his life in a school bathroom.
Police say it was a single gunshot. Students say it sounded like a stack of books being slammed to the ground.
The school went on lockdown, and parents came to pick up their children.
It's unclear where 15-year-old Triston Stephens got the gun or why he chose to end his life. For friends and classmates, the struggle to understand his decision may be a long one. Counselors who work in Coweta schools are fielding questions and concerns from not only kids, but parents as well.
An impromptu memorial is growing at Coweta Intermediate High, and so are the emotions surrounding the suicide of Triston Stephens.
2/4/2013 Related Story: Coweta Community Reacts To Freshman Student's Suicide
"It's scary, because I never thought it could happen in Coweta, but it did, and I guess we have to live with that now," said one of Triston's classmates.
She said he was nice, but different.
"He didn't have many friends, he was kind of an outcast and everyone made fun of him in the hallways," she said. "His hair, he dyed it different colors every other week, and he just wasn't like everyone else."
She said Triston was always sweet to her and when she said hi to him the day of the shooting, nothing seemed wrong.
"Everyone thought he wasn't smart and he was dumb, but in all reality, he helped me with my math and I couldn't do it," she said.
"This is a community tragedy," said counselor Sandy Shrum.
2/4/2013 Related Story: Police: Coweta Student Dead Of Self-Inflicted Gunshot Wound
Shrum is from Coweta and works with a counseling company that contracts with Coweta schools. She never counseled Triston, but said when it comes to suicide, teenagers often don't understand the permanency of it.
"Most of them like this are seeking attention, they are hurting inside, they want somebody there for them, they are reaching out the only way they know how to reach out," Shrum said.
We may never know what Triston's personal battle was, but the hardship now lies on the people he left behind.
"They may be dealing with this, not just today and tomorrow, but for lots of days to come and months to come. We're just going to be here for them," Shrum said.
Shrum encourages parents to talk to their kids about the school suicide. She says don't ask questions, just listen and let the children do the talking.
Coweta Public Schools has asked several counselors, including Shrum, to be on campus Tuesday for students and faculty who feel they need to talk.
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J.D.'s brother holds Drew to form
J.D.'s brother holds Drew to form
Don't prejudge new Sox shortstop
Don't prejudge new Sox shortstop
Let's just get this out of the way: Stephen Drew is not J.D.
Yes, they're brothers. Yes, they're left-handed hitters signed by the Red Sox. Yes, they often make the game look effortless.
But they're different people with different personalities, and for all the good J.D. did over five years here — most notably his postseason heroics — he'd be the first to admit that Red Sox fans don't always remember him fondly.
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Callahan: Obvious plan: Go for it
They were coming off a 12-4 regular season and another division title.


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The British Textile Machinery Association is your link to the best of British textile machinery and related products. It brings together British textile machinery and equipment manufacturers and the needs of the global textile and textile related industries.
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Celebrating the innovation & Hertiage of the British Textile Industry, the directory gives full details of all the members.


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HUNTINGTON -- Devin Arrington loves being back at linebacker for the Marshall University football team. Yet, in his mind, he doesn't feel totally back.
"I'm fortunate that we've got two more weeks left before any serious play, because I've still got a lot of work to do," he said. "But I'm getting there."
His tour of duty as a strong safety, a move made to shore up a shallow depth chart, lasted one season. A strong-side linebacker his first two years, he's now on the weak side and in the process of recalibrating himself for his new role.
While the blitzes and some of his techniques returned quickly, the 6-foot-3, 210-pound redshirt senior said he's still honing his linebacker reads.
"Linebacker is a read-react position," he said. "That's what it's all about, your reads. If your reads aren't on key, you're playing slow.
"I know myself. I know that when it's time to go, I'll have it down pat like the back of my hand."
Arrington has been a major contributor in both roles as a member of the Thundering Herd. He started 11 of 12 games at strong-side linebacker as a redshirt sophomore finishing sixth on the team with 64 tackles, including four for a loss, 1.5 sacks and three pass breakups. As a redshirt junior, he started all 13 games at safety, finishing tied for fourth with 77 tackles, including 2.5 for a loss, two interceptions and four pass breakups.
Safety wasn't a foreign position for him. He played there at Deep Creek High School in Virginia and said he practiced at that position during his redshirt year.
But when it came to on-field college competition, he was a linebacker until last season.
Marshall head Coach Doc Holliday said that safety experience should help in Arrington's return to linebacker.
"The transition playing safety for a year, he was forced to play in space the entire time," Holliday said. "I think moving up to that second level has helped him because of the space and the plays he had to make at safety."