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DEPARTMENTS & CENTERS OFFICE OF THE DEAN FACULTY UNDERGRADUATES GRADUATE STUDENTS PreMed Advising Office ALUMNI CORPORATE INTERESTS WHAT'S NEW
For information about UMBC Admissions or to apply online, please visit: http://www.umbc.edu/undergraduate/apply_now/
There are student groups organized to support CNMS undergraduates. These groups, which meet regularly, are student directed and focused on the interests of student members. For additional information, visit the websites:
Biology Council of Majors (BioCOM)
American Chemical Society Student Affiliates at UMBC (ACS)
Pi Mu Epsilon (PME)
The Society of Physics Students (SPS) and Sigma Pi Sigma CNMS Departments host several excellent summer research training opportunities that attract top undergraduates from UMBC and schools nationwide. REU Site: Interdisciplinary Program in High Performance Computing - an eight week program in high performance computing supported by the National Science Foundation. Students work in teams on projects brought in by high caliber researchers from academia and industry, closely supported by experienced graduate students and faculty members in collaboration with the Center for Interdisciplinary Research and Consulting (CIRC) at UMBC. Program Directors: Dr. Nagaraj Neerchal and Dr. Matthias Gobbert http://www.umbc.edu/hpcreu/ Center for Research and Exploration in Space Science & Technology (CRESST) Summer Internship Programs a ten week program of research experiences guided by mentors at NASA's Goddard Space Flight Center (NASA/GSFC) in Greenbelt, Md. CRESST Associate Program Director: Dr. Ian George http://cresst.umd.edu/Opportunities/internship2013.html
The Summer Biomedical Training Program (SBTP) is funded by UMBC and The Leadership Alliance. Program Director: Dr. Michael Summers Associate Director: Justine Johnson http://www.umbc.edu/meyerhoff/Undergrad/summer/ For information about other summer opportunities near and far, visit the links on the Office of Undergraduate Education website. Please be sure to investigate all information provided, especially program deadlines, as this information frequently changes.
Minority Access to Research Careers Undergraduate Student Training in Academic Research (MARC U*STAR) at UMBC, a federally-funded preeminent undergraduate research training program for select undergraduate juniors and seniors who plan to pursue Ph.D. degrees and careers in the biomedical sciences or mathematics. Director: Dr. Lasse Lindahl, Professor and Chair of the Department of Biological Sciences. Assistant Director: Ms. Taifa Hibbert http://www.umbc.edu/MARC
Each year, undergraduates, graduate students, staff and faculty attend the Annual Biomedical Research Conference for Minority Students (ABRCMS). Many attendees are scholars with the MARC and Meyerhoff Programs at UMBC. The 2009-2010 academic year was the third and final year of the CCCSTEP at UMBC. This initiative helped to provide the foundation for two collaborative STEM transfer student success grants that have been awarded to UMBC from the Bill and Melinda Gates Foundation. CNMS Home


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SWM Services GmbH reports additional generation units
2012/01/25SWM Services GmbH reports additional generation units: Today, SWM Services GmbH has started to provide additional generation data for its co-generation unit Freimann (160 MW) to the platform "Transparency in Energy Markets". The degree of data coverage in the Statutory Publication Requirements section for Germany increases from 93.53 to 93.62 per cent.
The degree of coverage of the statutory section is calculated as ratio of the installed capacities reported to the platform and the sum of the effective installed capacity in German control areas.
SWM Services GmbH operates generation facilities of 1,169 MW.

subset: commoncrawl


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The Pew Charitable Trusts is driven by the power of knowledge to solve today's most challenging problems. Pew applies a rigorous, analytical approach to improve public policy, inform the public and stimulate civic life.
Stay updated with Pew News Now! We invite you to sign up to receive our weekly e-mail newsletter.
Pew offers news delivered to your desktop via RSS feed. Subscribing is easy. To learn more or get started, follow the link below.
Subscribe to News Feed
Source Organization: Pew Charitable Trusts
Speaker: Neal Wolin
Venue: C-SPAN
04/19/2011 - The Pew Financial Reform Project hosted US Deputy Treasury Secretary Neal Wolin on Tuesday, April 19, 2011 for a discussion of the implementation of the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010 (Dodd-Frank).Deputy Secretary Wolin discussed the importance of moving forward quickly, carefully, and responsibly to implement the critical protections in Dodd-Frank. He then took questions from the audience.President Obama signed Dodd-Frank into law on July 21, 2010.Click here to view the text of the entire speech as prepared for delivery. Click here to view the video of the speech on C-SPAN2.Pew is no longer active in this line of work, but for more information, visit the main Pew Financial Reform page.


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Our friend and one of our favorite Art Dossier artists, Chad Kouri, gave Design Sponge a sneak peek of the fabulous Chicago-based apartment he shares with his lovely lady, Margot. This is just a taste and you can click through to see the rest of their rad digs from Design Sponge here.
Image above: Stow & Davis teak chairs and gallery-style wall. Clockwise from top: Nicole Lavelle; Collector's Plate is by Christopher Simmons; wood lettering by Matthew Hoffman; small abstract painting is by Nick Butcher; a vintage outtake from Chad's dad's senior high school portrait session; thrifted scissors; 2012 calendar by Debbie Carlos; and collage by Julia Hendrickson.
Tags: Chad Kouri Design Sponge Margot Harrington The Art Dossier collage
The Art Dossier is a communication platform that brings the latest news in contemporary art to readers worldwide in over 50 countries. w: theartdossier.com e: firstname.lastname@example.com


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OBEY Whiskey T-Shirt
$42.50 Item #64300OKN809- Distressed graphic 3/4 raglan sleeve nubby shirt
OBEY Whiskey T-Shirt 1 1
For the small only This is the first shirt I have to comment on and rate on this site. Although I truly love Buckle and Shepard Fairey's brand of clothing, I cannot recommend this for any guy. I just got the shirt in today, and I could have sworn I bought my girlfriend a shirt. The shirt was labeled a large, on tag and on the shirt itself, but it seriously can't even go lower than my torso, without even trying it on first. In a shorter statement, the shirt is way too small for any guy, including the models shown in the photo's. Returned it and asked about it, turns out all the shirts are printed like this. So word of warning to the guys, don't buy this for yourself. If your girl likes the Obey brand buy it for her. October 18, 2012
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Go-Ride Awards
While Phoenix riders have been scooping up titles over the past year, the staff have been busy too.
This week Richard Mould was recognised for his deserving work with the club as North East Go-Ride Coach of the year.
This comes days after Steve Walton was also honoured as Club Official, meaning Phoenix claimed 2 of the four awards on offer.
They will be presented on March 22nd at the Go-Ride Conference in Hetton
Phoenix riders are standing out in the current Cyclo-Cross series.
Daniel Saba, Grace Castle, Nathan Castle, Beth Orchard, Chris Orchard, Jake Dobson, Ben Scott, Will Hetherington, Jack Newton, Tim Newton and Charles Lewis can all be seen getting muddy in the name of fun and some valuable competition pace training. Have a look at the CXNE site for details
Get Down & Dirty Round 5 Results
21 riders enjoyed a speedy event in weather conditions a sharp contrast to the last round.
Boys race captain Cameron Thompson turned in a measured performance to cross the line first, but he was pushed all the way to the line by Jay Dixon. Matthew Green also turned in a fine ride as he finished third.
Get Down & Dirty Round 4 Results
17 riders endured grotty weather conditions in Round 4 of the current series
Unfortunately the weather hampered preparations for the event as certain parts of the intended course we waterlogged and caused a few anxious moments while we worked out an alternative and caused a sizeable delay for which we apologise.
Get Down & Dirty Round 3 Results
23 riders competed in Saturday's round of the current series, the Round 3 Power Climb TT
Boy's team Captain Cameron Thompson produced a perfectly measured effort to post the days fastest time in the U14 and the event overall. Jonah Davies-Jones won the U12 and Grace Castle the U10, while Ben Scott was best U8. Grace Castle was best U10 girl and best overall girl.
Eurosport Newsfeed
BBC Newsfeed
Cycling News MTB
Something to try at Home!
Captains Blogs
Grace Castle:
It's a real honour to be elected race captain for girls in my first season of racing.
Jake Dobson:
A quick update on the 2013 season and a few plans for 2014!
Read more...Beth Orchard:
Back in the Saddle
Beth looks forward to the new season after last years disappointment.
Read more...Cameron Thompson:
I was shocked but delighted to be elected as the Boys club captain at the recent AGM.


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Originally published on Wed March 13, 2013 7:27 pm
The Internet is a battleground in Syria, a place where President Bashar Assad's regime has mounted a sophisticated surveillance campaign that includes monitoring and arresting activists by tracking their Facebook pages.
The Syrian Electronic Army, an arm of the Syrian military, is in charge of the monitoring.
Originally published on Wed March 13, 2013 4:36 pm
Following a circuitous route from Saudi Arabia up through Turkey or Jordan and then crossing a lawless border, hundreds of young Saudis are secretly making their way into Syria to join groups fighting against the government of Syrian President Bashar Assad, GlobalPost has learned.
With the tacit approval from the House of Saud and financial support from wealthy Saudi elites, the young men take up arms in what Saudi clerics have called a "jihad," or "holy war," against the Assad regime.
Originally published on Thu March 14, 2013 11:05 am
If aging is not for sissies, that's especially true if you're homeless. You can be on your feet for hours, or forced to sleep in the frigid cold or seriously ill with no place to go. But, increasingly, the nation's homeless population is getting older. By some estimates, more than half of single homeless adults are 47 or older.
And there's growing alarm about what this means — both for the aging homeless and for those who have to foot the bill. The cost to society, especially for health care and social services, could mushroom.
Republicans have a steep hill to climb if they want to take control of the Senate next year. The GOP would need to pick up six seats in 2014.
There are plenty of open seats and vulnerable Democrats up for re-election, but Republicans are debating the best way to win.
Last year's Senate results were disappointing for the GOP: The party ended up losing a number of seats it thought were winnable — and now it's trying to figure out what to do differently next year.
Several years ago I gave a speech in which I mentioned that athletes tended to be the only college students who were awarded scholarships for what is an extracurricular activity.
Afterward, Myles Brand, the late president of the NCAA, told me I was wrong, that many music extracurricular scholarships were awarded at colleges.
Brand and I seldom agreed on much of anything, but I've always found him to be a gentleman. So, I expressed surprise at this claim.
OKLAHOMA CITY (AP) — Oklahoma's secretary of finance says state income tax refunds and a drop in natural gas production reduced general revenue fund receipts last month.
Secretary of Finance and Revenue Preston Doerflinger said Tuesday that collections totaled about $255 million in February. That's almost $29 million below collections in February 2012 and $20 million lower than the official estimate upon which this year's budget is based.
OKLAHOMA CITY (AP) — The Oklahoma Senate has approved legislation to privatize the state's nonprofit workers' compensation agency.
The Senate passed the measure Tuesday by a vote of 36-11. It heads to the House, where a similar bill is pending.
The bill by Senate President Pro Tem Brian Bingman of Sapulpa would convert CompSource Oklahoma from a state entity to a private company owned by its policyholders. Supporters say a state agency should not by competing with private insurers.
OKLAHOMA CITY (AP) — The Oklahoma Senate has approved legislation that would transfer management of the unfinished American Indian Museum from the museum's board to another agency.
The Senate voted 26-20 for the measure Tuesday and sent it to the state House for consideration.
OKLAHOMA CITY (AP) — A bill to provide a 5 percent pay increase for Oklahoma's prison workers has stalled in a House committee.
The House Calendar Committee on Tuesday tabled the bill by Darcoma Republican Rep. Jeff Hickman. Aside from a 5 percent pay hike for all prison workers, the bill would have boosted the starting pay for correctional officers from $11.83 per hour to $14 per hour. It would have cost about $12.2 million annually and was the top request by the Department of Corrections for additional funding.
McALESTER, Okla. (AP) — Oklahoma executes man for 1999 death of Tulsa-area woman that began 3-state killing spree.


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Welcome to Wedding Belles!
Hi! I'm Hannah and I'm a fine art & documentary wedding photographer based in Cambridge. I photograph weddings predominately in London, Cambridge & internationally but will cover other locations in the UK. I love to travel and welcome any opportunity to photograph a beautiful wedding abroad. I am now taking bookings for 2014, please do get in touch and say hello, I am always happy to answer any questions that you may have about your wedding day.
Latest Posts


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Josh the Jerk Idiot must be getting a paycheck. Hey Josh any truck driver could have told you about the Jerk in the White House. Nowitall college jerk. Click Here if you Like this Comment 1 person like this.
Josh is a young man, who made a young man´s mistake. It sounds like he knows better now. Click Here if you Like this Comment
I too came to my senses at 26, and have retained them now for more than 30 years. My idea of the Republican "big tent" has absolutely nothing to to do with tribalist nonsense like race, gender, ethnicity, age. It has to do with the individual mind and whether it can grasp the concepts of freedom and responsibility. Sounds to me as if Josh has now passed the test. I hope we can save our bashing for those who have not. Click Here if you Like this Comment
Easy #1. The young man has admitted his mistake and will be better for it. How many others who are older than him are still stuck on stooooopid ? Click Here if you Like this Comment 1 person like this.
based on what my two college student sons tell me, college students are some of the biggest lofo voters out there. It´s so sad, considering what you would think a higher level educational environment is all about: critical thinking, the exchange of ideas... But it´s not like that. Click Here if you Like this Comment 1 person like this.
College education lost a lot of value right about the time affirmative action started being pushed by the government and the quality of education had to be dumbed way down to compensate. The bar was already being lowered to cater to athletes but AA pushed it over the cliff. I´m wondering now when Asian families are going to figure out that they are wasting their money by sending their children to US schools when their own are probably better at this point in time. Click Here if you Like this Comment 1 person like this.
This is what is wrong with Brain-dead morons like Josh! His parents did not raise him think independently, but think in a "group think". Click Here if you Like this Comment 1 person like this.
Higher education lost its value when the federal government began passing out money hand over fist to fund anyone and everyone to go to school. Call me a jerk, but not everyone should be in a university, especially on the tax-payer´s dime. Click Here if you Like this Comment 1 person like this.
Josh?Now you can really make the world a better place and transform the USA ...... inform your friends and convince them to vote right next time.Otherwise - you haven´t learned a thing.A mind is a terrible thing to waste, Josh. Click Here if you Like this Comment 1 person like this.
The decline of college education has resulted from political correctness trumping critical thinking, the various "Studies" programs be treated as serious curricula; how many employers are looking for graduates who majored in Chicano Studies? Grade inflation has played no small part. It used to be that the dolts would get a "gentleman´s C", now they get an A for showing up. Freshmen now are routinely enrolled in remedial programs so that they can catch up on all the stuff they didn´t learn in high school. However, if you want to spend four years swilling beer, doing drugs and bedding bimbos, college ain´t a bad place to be at all. Click Here if you Like this Comment 1 person like this.
Break the Teacher Unions, Public Unions, support Charter schools, home school, do not send your child to the public school camps..this is our last possible hope.. Click Here if you Like this Comment
Josh got a clue and got serious. Don´t you read the articles? Why are people jumping all over someone who is now on our side? One person insists that Josh must convince his peers of the error of their ways. What a responsibility to put on his shoulders. It is a mission impossible. Forgive us, Josh, for our unreasonable and unrelenting insistence on flogging our own. Click Here if you Like this Comment 1 person like this.
Give this kid a break. Most of us probably had 100 times better education than what is being dished out today. The fact that he was able to "figure it out" tells you that there is hope. Click Here if you Like this Comment 1 person like this.
Josh was understandably confused in the Obama- McCain election. How could a new voter tell the candidates apart? Aside from the fact that one had defended his country and had decades of experience in government and military command, and the other had given up his law license, had no experience in business, made little impact in the state legislature, probably less in the Congress, and that the younger candidate´s platform was clearly and admittedly to " spread the wealth ", which requires government to take money from one citizen and give it to another, what was there to choose between them? Not like Parcheesi or Tiddlywkinks, and therefore too complex for Josh. Click Here if you Like this Comment
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Gift ideaSeason ticketsOpera season tickets Premières & Dernières Week Weekend Matinee Flexible season tickets Opera programme subscriptionDance and theatre season ticketsConcert & recital season tickets Concert series Recital series À la carteSeason tickets for young people under age 30 OpassSeason ticket office |
Season tickets for people under age 30People under age 30 receive 50% off all season ticket formulas! When you purchase a season ticket, you will receive a Go!pera card, which allows you to enjoy many other advantages.
A € 5 fee is added to all the prices mentioned. |


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Packaging Details: Sold individually
Availability: Ships same day or next business day
Shipping Weight: 10 pounds
Multi-roll dispenser holds rolls with a core size up to 3". Adjustable roll dividers can hold tape or labels of any width. Heavy steel construction with nonskid suction base ensures stability and performance. 12"-long dispenser.


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Women's Soccer Roster
2010(Senior): One of three players to start all 20 games… was the team's second leading goal scorer with 10… added 3 assists… filled in as keeper in 4 games this season due to injury, totaling 266 minutes and 14 saves… named a 2010 Daktronics-NAIA Women's Soccer Scholar-Athlete
2009 (Junior): Started 13 games out of 21 appearances... scored seven goals and registered one assist for a total of 15 points, fourth on the team in that category... seven goals ranked third on the team... game winners against Berea (Ky.) and against Brescia (Ky.) in the KIAC Championship... Fifth on the team with 31 shots, 13 coming on-goal.
2008 (Sophomore): Appeared in 21 games, earning 7 starts... scored five goals with one assist totaling 11 points... scored twice in games against Midway (Ky.) and Campbellsville (Ky.)... assisted on the game winning goal against conference foe, Mountain State (W.Va.)... registered 25 total shots.
2007 (Freshman): Appeared in 15 games, earning 2 starts, one coming in goal against Cedarville (Ohio)... registered 5 shots on-goal out of 7 total shots... earned half shutout against Oakland City (Ind.) in her only other appearance in goal on 9/6/2007.
High School: Played four years of varsity soccer at Ryle... earned 2005 Regional MVP honors and a 2006 All-District Tournament Team selection... also played softball... played club for the Classics, based in Cincinnati, Ohio.


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SHANGHAI – Supported by unprecedented demand for all of their major brands, General Motors and its joint ventures sold a record 2,836,128 vehicles in China in 2012. Sales increased 11.3 percent from 2011.
"GM remained a leader in our company's largest market in spite of a downturn in the commercial vehicle segment, where GM has a significant presence," said Bob Socia, President, GM China, and Chief Country Operations Officer, China, India and ASEAN. "We benefited from a broad portfolio of models that are meeting the diverse needs of vehicle buyers across China."
Growing Sales
Domestic sales by Shanghai GM rose 10.9 percent last year to a record 1,331,022 units. SAIC-GM-Wuling sold 1,445,203 units in China, an increase of 12.4 percent and an all-time high as well. FAW-GM's domestic sales were down 0.9 percent to 55,609 units.
Buick sales in China increased 8.4 percent on an annual basis, finishing 2012 at a year-end high of 700,007 units. The brand was supported by ongoing strong demand for the original Excelle family, whose sales grew 9.3 percent to 277,071 units, and the Excelle XT and GT, whose sales were up 28.6 percent to 173,312 units. The Encore SUV got off to a strong start following its launch in October, with sales of 10,015 units.
Chevrolet likewise set a record for domestic sales, as demand increased 5.3 percent from 2011 to 626,846 units. Its most popular model was the Cruze, which generated sales growth of 5.2 percent to 232,592 units. Right behind it was the Sail, which had sales of 218,090 units, an increase of 30.8 percent. The brand's newest model in China, the Malibu, had sales of 51,926 units.
Cadillac sales in China were up slightly in 2012 from the previous year to a record 30,010 units. GM's luxury brand was led by the SRX, which sold 21,698 units – an increase of 8.9 percent.
Wuling sales in the domestic market rose 11.8 percent year on year to 1,334,895 units, which was also a new annual high. The Sunshine minivan, its best-selling model for the past nine years, surpassed half a million unit sales for the fourth consecutive year. Baojun had sales of 84,467 units in its first full year in the marketplace.
In addition, exports by GM's manufacturing joint ventures to other emerging markets grew 61.0 percent last year to 77,207 units. The Sail accounted for about 80 percent. This took Shanghai GM's total sales in 2012 to 1,392,658 units, SAIC-GM-Wuling's sales to 1,459,988 units and FAW-GM's sales to 56,395 units.
During December, GM and its joint ventures sold a record 242,486 vehicles in the domestic market, an increase of 23.2 percent on an annual basis. Shanghai GM's domestic sales increased 41.7 percent to 110,135 units, while SAIC-GM-Wuling's sales in China were up 11.7 percent to 126,730 units. Both were December records. FAW-GM's sales were down 0.1 percent to 5,264 units.
Growing Presence
"GM continued to look to the future in China in 2012," said Socia. "We introduced several new and upgraded products, grew our manufacturing footprint, and expanded our R&D and product development capability."
The Chevrolet Malibu and Buick Encore were among the new models that GM began offering in China last year. Shanghai OnStar rolled out a range of new services for Buick, Chevrolet and Cadillac owners, helping the joint venture become the first telematics service provider in China with more than 500,000 subscribers.
Shanghai GM and SAIC-GM-Wuling both expanded the capacity at several of their existing manufacturing facilities. In addition, Shanghai GM broke ground for its fourth manufacturing base in Wuhan, Hubei. SAIC-GM-Wuling opened its new passenger car production facility near its headquarters in Liuzhou, Guangxi, and announced plans to build a third production base in Chongqing Municipality.
Meanwhile, GM continued to expand the dealership networks of all of its brands, with a focus on China's tier 3 and tier 4 cities. GM ended 2012 with about 3,800 dealerships nationwide.
To support the ongoing development of products for China and the world, GM's Pan Asia Technical Automotive Center (PATAC) joint venture opened a climate wind tunnel in Shanghai, and GM China and its partner SAIC joined Shanghai GM and PATAC in opening the Guangde Proving Ground in Anhui province. The GM China Advanced Technical Center recorded milestones in lightweight materials and electric vehicle battery development during its first full year of operation, while opening its second phase in November.
GM maintained its support for a greener, safer and healthier community in China as well. Among the key programs launched last year were the GM Restoring Nature's Habitat Project, which is protecting important wetlands; the 2012 GM Safe Road Project, which educated young families about the importance of using safety equipment in vehicles; and the Back to 100 Rural Hospitals and SAIC-GM-Wuling Motorcade initiatives, which are assisting with health care in rural areas.
General Motors traces its roots back to 1908. GM has 12 joint ventures, two wholly owned foreign enterprises and more than 55,000 employees in China. GM and its joint ventures offer the broadest lineup of vehicles and brands among automakers in China. Passenger cars and commercial vehicles are sold under the Baojun, Buick, Cadillac, Chevrolet, Jiefang, Opel and Wuling brands. In 2012, GM sold more than 2.8 million vehicles in China. It has been the sales leader among global automakers in the market for several years. More information on General Motors in China can be found at GM Media Online. Click here to see GM China's milestones in 2012.


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Artist: | French Montana |
Title: | Marble Floors |
Featuring: | Rick Ross , Lil Wayne , 2 Chainz |
Album: | Excuse My French |
Producer: | Mike Will Made It |
Avg Rating: |
Fellas, do you know where your girl is right now? Because if she's not within eyeshot, there's a good chance, she might be tiptoein' across the Marble Floors at French Montana's place. On the latest single off his major label debut, the Bad Boy signee gives listeners a guided tour of his palatial digs, … Read More


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Safety and Efficacy Study of BT086 to Evaluate Adjunctive Therapy in sCAP (CIGMA)
- Full Text View
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to determine whether the adjunctive therapy to standard antibiotic treatment of BT086 is safe and effective of decreasing the days patients require endotracheal ventilation due to Severe Community-Acquired Pneumonia (sCAP).
Condition | Intervention | Phase |
Community Acquired Pneumonia |
Drug: BT086 Drug: 1% Human Albumin infusion |
Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor) Primary Purpose: Treatment |
Official Title: | A Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group, Adaptive Group-sequential Phase II Study, to Determine the Efficacy and Safety of BT086 as an Adjunctive Treatment in Severe Community Acquired Pneumonia (sCAP) |
- Ventilator Free Days [ Time Frame: 28 days ] [ Designated as safety issue: No ]VFDs are defined as the number of days between successful weaning from endotracheal ventilation and day 28 after study enrolment.
- 28-day all cause mortality [ Time Frame: 28 days (672 hours from randomization) ] [ Designated as safety issue: No ]All patients will be classified as either "alive at Study Day 28" or, if dead, "dead at Study Day 28", regardless of cause of death.
- 28-day pneumonia-cause mortality [ Time Frame: 28 days (672 hours from randomization) ] [ Designated as safety issue: No ]All patients will be classified as either "alive at Study Day 28" or, if dead, "dead at Study Day 28, with pneumonia as cause of death".
- Time (days) to discharge from ICU [ Time Frame: 28 days ] [ Designated as safety issue: No ]The date and time of admission to and discharge from the ICU will be recorded in the CRF. The time to discharge from the ICU will be calculated as the number of days spent in the ICU.
- Time (days) to discharge from hospital [ Time Frame: 28 days ] [ Designated as safety issue: No ]The date and time of admission to and discharge from the hospital will be recorded in the CRF. The time to discharge from the hospital will be calculated as the number of days spent in the hospital.
- SOFA: Score Sequential Organ Failure Assessment [ Time Frame: 28 days ] [ Designated as safety issue: No ]Each organ system (cardiovascular, haematology, hepatic, renal, respiratory) will be scored using the SOFA methodology.For analysis, a patient will receive a score on each day (Study Days 1-7, Day 14, Day 21, and Day 28). Mean changes in organ function scores over time and percentages of patients whose organ function has resolved will be compared between treatment groups.
- Vasopressor-free days [ Time Frame: 28 days ] [ Designated as safety issue: No ]
Vasopressor-free days will be calculated in a similar manner to VFDs, as described above. Vasopressors include doputamine, epinephrine, dopamine, and norepinephrine.
A day is considered as a vasopressor-free day if a patient does not receive
- Doputamine >2.5 µg/kg/min or/and
- Epinephrine (adrenalin) >=2.5 µg/min or/and
- Dopamine >=2.5 µg/kg/min or/and
- Norepinephrine >=0.014 µg/kg/min for 4 hours per day.
Estimated Enrollment: | 82 |
Study Start Date: | August 2011 |
Estimated Study Completion Date: | May 2015 |
Estimated Primary Completion Date: | January 2015 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: BT086 infusion |
Drug: BT086
BT086 will be administered per intravenous infusion (IV). The dose to be administered is 3.65 mL /kg bw/day and is calculated by the mean IgM content of BT086 which is 23%. Infusion rate: Starting rate is 0.1 mL/min. Maximum infusion rate is 0.5 mL/min (target infusion rate) Treatment will be administered over a 5-day period. |
Placebo Comparator: 1% Human Albumin infusion |
Drug: 1% Human Albumin infusion
1% Albumin will be administered per intravenous infusion (IV). The dose to be administered is 3.65 mL /kg bw/day. Infusion rate:Starting rate is 0.1 mL/min. Maximum infusion rate is 0.5 mL/min (target infusion rate). Rate is to be raised in steps of 0.1 mL every 10 min until the target infusion rate is reached. Treatment will be administered over a 5-day period. Starting rate is 0.1 mL/min. Maximum infusion rate is 0.5 mL/min (target infusion rate) |
Detailed Description:
Severe Community-Acquired Pneumonia (sCAP) is usually defined clinically as pneumonia acquired from outside the hospital (CAP) that requires intensive medical care. Mortality of (s)CAP patients admitted to ICU range from 35-58% depending on time and admission of the patient and has not much improved in the last years.
BT086 contains a sufficient number of antibodies against the most frequent pathogens as well as antibodies against lipopolysaccharides and lipid A. Therefore, it can be assumed that administration of BT086 early in the clinical course of a severe infection such as sCAP may provide an effective adjunctive treatment to standard antibiotic therapy for sCAP patients.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Written informed consent:
- given by the patient or
- a legal/authorised representative of the patient or
- a waiver for written informed consent due to emergency situation, in compliance with all local legal requirements.
- Male or female patients aged 18 years or older
- Patient receiving adequate antibiotic treatment for pneumonia
Prior to endotracheal ventilation and therapy, the patient must have at least one of the following two signs of inflammation:
- Fever/Hypothermia Fever defined as an oral temperature of >38°C, tympanic temperature of >38°C or rectal temperature of >38.5°C, or hypothermia (rectal temperature <35.5°C) or
- White blood cell (WBC) count >10,000/mm³ or WBC <4,500/mm³
Patient must have at least one of the following signs and symptoms of pneumonia:
- New or increased cough
- Production of purulent sputum or change in sputum characteristics
- Dyspnoea or tachypnoea (respiratory rate >20 breaths/minute)
- Pleuritic chest pain
- Auscultatory findings on pulmonary examination of rales and/or crackles and/or evidence of pulmonary consolidation (e.g. dullness on percussion, bronchial breath sounds, or egophony)
- Radiological (or other imaging technique) evidence of (an) infiltrate(s) consistent with bacterial pneumonia
- Pneumonia has been acquired outside the hospital. In hospital-admitted patients, pneumonia has been diagnosed a maximum of 72 hours after admission. Patients from nursing homes or similar institutions are eligible.
- Major sCAP criterion: need for endotracheal ventilation
- Treatment of patient with BT086 must start within 12 hours but not earlier than 1 hour after start of endotracheal ventilation
Exclusion Criteria:
- For incapacitated patients: any indication that the patient's presumed will would be against inclusion in the trial
- Patients with suspected hospital-acquired pneumonia
- Severe lung diseases interfering with sCAP therapy e.g. patients with cystic fibrosis,
- Patients receiving Xigris® (drotrecogin alfa, activated Protein C) or medications not approved for sCAP (e.g. Dornase alpha) are excluded from inclusion in the study
- Patients on dialysis
- Presence of other severe diseases impairing life expectancy (e.g. patients are not expected to survive 28 days given their pre-existing uncorrectable medical condition).
- Patients unable to be treated due to obesity
- Selective, absolute IgA deficiency with known antibodies to IgA
- Patients with neutrophil count <1,000/mm³ or platelet count <50,000/mm³
- Pregnant or lactating women. A pregnancy test will be performed in all women aged <65 years and the result must be available at study inclusion.
- Known relevant intolerance to immunoglobulins, vaccines or other substances of human origin
- Participation in another interventional clinical trial within 30 days before entering the study or during the study, and/or previous participation in this study (participation in non-interventional trials is allowed).
Contact: Andrea Wartenberg-Demand, MD | ++49 6103 801 ext 497 | firstname.lastname@example.com |
Contact: Iris Bobenhausen, PhD | ++49 6103 801 ext 2124 | email@example.com |
Germany | |
Universitätsklinikum Halle | Recruiting |
Halle/Saale, Germany, 06120 | |
Contact: Hennig Ebelt, MD +49 345-557 ext 2001 email@example.com | |
Contact: Kathrin Ludwig +49 (0)345 557 ext 2113 firstname.lastname@example.com | |
Principal Investigator: Hennig Ebelt, MD | |
Medizinische Hochschule Hannover | Recruiting |
Hannover, Germany, 30625 | |
Contact: Welte Tobias, MD +49 511532 ext 3530 email@example.com | |
Contact: Rabea Gatzke +49 511532 ext 3454 firstname.lastname@example.com | |
Principal Investigator: Tobias Welte, MD |
Principal Investigator: | Tobias Welte, MD | Hannover Medical School |
No publications provided
Responsible Party: | Biotest |
ClinicalTrials.gov Identifier: | NCT01420744 History of Changes |
Other Study ID Numbers: | CIGMA Study 982 |
Study First Received: | August 19, 2011 |
Last Updated: | May 27, 2013 |
Health Authority: | Germany: Paul-Ehrlich-Institut Spain: Agencia Española de Medicamentos y Productos Sanitarios |
Keywords provided by Biotest:
Endotracheal ventilation Bacterial pneumonia |
Additional relevant MeSH terms:
Pneumonia Lung Diseases Respiratory Tract Diseases Respiratory Tract Infections |
ClinicalTrials.gov processed this record on March 06, 2014


text:
Waratahs show Maori and Pacific Island links
waratahs.com.au and James Mortimer - (26/03/2013)
Wycliff Palu and Tatafu Polota Nau joined thousands of Islanders and Maori at Holroyd Oval in Parramatta on Saturday, taking part in the Taki Toa Festival, a celebration of the Pacific Island and Maori cultures.
Taking over the reins from his father who conceived the festival, Maori organiser Manu Sutherland, says the event uses sport to integrate a number of cultures together. "My father came up with the idea and carved the shield over 30 years ago and then passed it over to me."
In celebrating the cultures, rugby seemed to be the key denominator, as Manu says. "The festival is a means of getting Kiwis and Polynesians together and rugby was the key link."
Palu and Polota-Nau spent the day at the festival, getting involved with all that was on offer. They were a big hit, especially with the kids, as they handed out mini footies and awarded a number of ticket prizes to forthcoming HSBC Waratahs home matches. The day was particularly symbolic for Polota-Nau, as he was on home ground having represented the Merrylands-based Parramatta Rugby Club since his junior days.
The Festival began early with a traditional welcoming ceremony by the Maori elders, known as a powhiri. This was followed by a powerful Haka challenge, which excited the crowd, preparing them for the fierce competition ahead.
After the netball tournament, the event's main attraction – the Taki Toa Rugby Tournament – got underway. The Te Moana -Nui-a-Kiwa rugby team were the eventual winners of the prestigious Taki Toa Shield, which was formally presented at the end of the day.
Last year's winners, Merrylands Rugby Club, hosted the event to great success with a few thousand people, young and old, turning out for the huge day-long festival of culture and all the activities.
The day also marked the beginning of an important new union between the HSBC Waratahs and the Taki Toa Festival, which looks set to continue in future years with the successful establishment of this sporting and cultural festival.


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House of Balloons last night
Please, mercy me, mercy me. Let me fall out of love before you fuck her, before you fuck her.
Oui, j'ai pleuré mais ce jour làNon, je ne pleurerai pas
The Weeknd - Montreal
D.D. - The Weeknd
Don't make me make you fall in love with a n- like me
The Birds Part 1 - The Weeknd
Trust Issues - Drake & The Weeknd


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What is your current job, including title and responsibilities?
I am a Vice President / Transaction Manager within Bank of America's Corporate Workplace. Our group is responsible for the end-to-end development and management of the Bank's corporate real-estate (banking centers, administrative buildings and data centers). I'm responsible for transacting on the 9 million square feet of administrative real-estate within New England, most of which is legacy Fleet and MBNA.
What major projects have you been working on in your career? Results?
Occupancy expense is the Bank's second largest expense (after payroll), so there's always a focus on optimizing the Bank's footprint in all of its markets. I'm working on a few significant initiatives specific to New England which are looking to ensure that our footprint is meeting the needs of the various lines of business in the most cost-effective manner possible. Reducing occupancy expense will be a major focus in 2009.
Have you felt the impact of the global recession in your job?
No company, least of all Bank of America with its extensive international reach, is immune to the current economic struggles facing the global community. That said, the current environment poses growth opportunities for those with capital as evidenced by the Bank's recent acquisitions of Countrywide and Merrill Lynch. The integration of the real-estate associated with these two companies will be cumbersome in the short-term but should provide significant economies-of-scale going forward.
How do you think the Graaskamp Center has helped your success?
The greatest contribution the Center made to my professional development was that it provided me access: It provided me access to some of the top Real Estate faculty in the country. It provided me access to international markets via the trips to France, China, and Japan. It provided me access to guest speakers and special events which helped develop my understanding of the development process and real estate finance. And lastly, the Center provided me access to alumni, which was one of the main factors in how I became interested in my current job at Bank of America.
Knowing what you know now, what advice do you have for your fellow Graaskamp students?
Obviously, the current environment has made this one of the most challenging job markets in memory and will require you to work harder to get a job than graduates of recent years. That being said, right now you have the ability to learn from and ask questions of true academics and sit in on lectures that few others can attend. You have the opportunity to gather insights in real-time from people who have devoted their lives to studying the very issues that are profoundly impacting the world on a daily basis. Take full advantage of the cover that being in an academic setting provides and use this time to reflect not only on the world in which we live but also on how want to make your mark.
Associate. As the analyst for one of BlackRock's Flagship REIT Funds, my key focus is the analysis of portfolio and property performance and evaluation of risk/return attributes.
What major projects have you been working on in your career?
Yes. After experiencing a few "right sizing" rounds, I realize the importance of having the right mix of experience, education, exceptional past performance, credentials, and a strong internal network. With that in mind, this is an excellent time for a career development. I have worked with senior leadership to identify additional training that they feel will add value to the firm during these difficult times. Not only will my career development benefit the firm, it will also help me to remain competitive and highly marketable.
What future goals do you have?
My education provided a solid understanding of real estate fundamentals and market mechanics that helped to flatten the learning curve.
I am currently an employee at GLL Real Estate Partners. I am the financial leader for all of Europe for the Asset Management Group. GLL has made intentional efforts to not get caught up in titles, but effectively I'm the Financial Lead for Western, Central, and Eastern Europe for the Asset Management Group. I am responsible for controlling and knowing all of the financial information for the ~50 properties that we have across Europe.
In the short time that I've been here (5 months), I had accountability for Argus Modeling for Europe, Financial Responsibilities for the Budapest, Hungary market and have recently been made the financial lead of Asset Management for all of Europe. The resulting financial figures coming from our European portfolio have been the most reliable figures GLL Real Estate Partners has had in its short existence since I have become involved. Hopes are that the transparency and accuracy of figures will continue to improve in coming months.
Despite the fact that there is a global recession at hand, there have not been exceptional challenges that have arisen for GLL. The recession has actually created a great buying opportunity for European investors and Property Holding Companies like GLL as the Euro is still relatively strong (compared to the US Dollar) and property prices are decreasing. Furthermore, the crisis stresses the necessity to have financial transparency that provides investors enough confidence to continue making wise investments.
I have hopes to return to the United States at some point to work for an asset management company that has international accountabilities to leverage the experiences that I have had in Europe. I also have aspirations to be a leader and coach within every company that I work. I also believe that life can throw many curveballs which cannot always be planned for.
The Graaskamp Center as provided an incredibly invaluable experience to me. Not only has it taught me the most important fundamentals of real estate, it has also put me within arms reach of some of the most respectable, intelligent, and successful real estate professionals in the world. The Center has provided global learning interactions that exceeded my expectations many fold. The Graaskamp Center, most importantly, is lead by the most knowledgeable, well known, and respected professors and faculty members in the country.
I advise fellow Graaskamp students to do three things. 1- Study hard. The more you know, the better equipped you'll be to perform well and succeed in the future. 2- Network. Get to know some of the industry professionals, taking more time to listen, and ask questions to continue learning. 3- Build your character. Always do the right thing and respect everyone that you interact with, regardless of who they are, what their job is, or where they're from. Being smart, and being well known, isn't a good thing if you're known for not having integrity.


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Having launched his career on television, screenwriter and director Stephen Gaghan wrestled with his personal demons to emerge as the Oscar-winning writer of the acclaimed sociopolitical crime epic, "...
Read More...
BirthDate BirthPlace |
Louisville, Kentucky, USA |
Name |
Year |
Credit |
credited As |
Role |
Entourage: Welcome to the Jungle | Actor | n/a | 7 | |
The 58th Annual Golden Globe Awards | 2000 1999 - 2000 | Actor | n/a | 20007 |
Alfie | 2004 | Actor | Adam | 20047 |
Abandon | 2002 | Director | n/a | 4 |
Syriana | 2005 | Director | n/a | 4 |
Sleepwalkers | 1997 1996 - 1997 | Co-Producer | n/a | 1 |
Abandon | 2002 | Screenplay | n/a | 1 |
Traffic | 2000 | Screenplay | n/a | 1 |
Havoc | 2004 | Screenplay | (rewrite) | 1 |
Syriana | 2005 | Screenplay | (Adaptation) | 1 |
The Practice: Season: 1 | Story Editor | n/a | 1 | |
I Still Know What You Did Last Summer | 1998 | Screenplay | n/a | 1 |
Rules of Engagement | 2000 | Screenplay | n/a | 1 |
American Gothic: Season: 1 | Story Editor | n/a | 1 | |
The Practice: Season: 2 | Writer | n/a | 1 | |
NYPD Blue: Season: 4 | Writer | n/a | 1 | |
American Gothic | 1995 1994 - 1995 | Writer | n/a | 1 |
New York Undercover: Season: 1 | Writer | n/a | 1 | |
The Alamo | 2004 | Screenplay | n/a | 1 |
The Practice: Season: 2 | Story Editor | n/a | 1 |
Title |
Served as co-producer on the extremely short-lived (two episode) run of the NBC series "Sleepwalkers"; also co-wrote episodes |
With Michael R Perry, served as story editor and teleplay writer for the short-lived CBS series "American Gothic" |
While attending college in Massachusetts, began catalog company called Fallen Empire Inc; company eventually failed |
Helmed the geopolitical thriller "Syriana," based on the real-life memoirs of CIA agent Robert Baer and starring George Clooney and Matt Damon; earned an Oscar nomination for Best Original Screenplay |
Was on writing staff of the ABC drama "NYPD Blue"; shared Emmy award for the "Where's Swaldo?" episode; Perry also contributed to award-winning script |
Raised in Louisville, Kentucky |
Arrested on felony drug charges for possession of cocaine and heroin in October; later pleaded guilty to lesser charges of drug possession; sentenced to conditional discharge |
Settled in L.A. |
Feature film debut as screenwriter, "Rules of Engagement" |
Made feature directorial debut with "Abandon"; also scripted |
Served as executive story editor and occasional writer on the ABC drama series "The Practice"; continued collaboration with Michael R Perry |
Moved to NYC |
Penned the screenplay for "Traffic", based on the British miniseries "Traffick"; as he told The New York Times (February 5, 2000), some aspects of the film were based on his own experiences as a drug addict; received Oscar for Best Adapted Screenpl |
Born on May 6, 1965 in Louisville, KY, Gaghan was raised by his mother, Elizabeth, and his father, Stephen, whom she divorced in 1980. He attended the Kentucky Country Day School, a Louisville-based college preparatory school where he was a member of the state's all-star soccer team before beginning his descent into alcohol and drug addiction. On his last day of his senior year, Gaghan was expelled from Kentucky Country Day for allegedly driving a go-cart through the hallways. After later receiving his GED, he went to the University of Kentucky before attending Babson College, a private business school in Massachusetts. Because he was the grandson of Jerry Gaghan, a newspaper columnist and critic for both Variety and the Philadelphia Daily News, Gaghan harbored ambitions to become a writer. Eventually, he connected with writing partner Michael R. Perry, and made his debut on the small screen with a script for an episode of "New York Undercover" (Fox, 1994-98). The pair quickly segued to the positions of story editor and writers for the short-lived cult drama "American Gothic" (CBS, 1995-96) and the acclaimed procedural "NYPD Blue" (ABC, 1993-2005).
During their one-season stint on "NYPD Blue," Gaghan and Perry shared an Emmy Award with executive producer David Milch for the "Where's Swaldo?" episode. Meanwhile, the writing team moved over to David E. Kelley's successful legal drama, "The Practice" (ABC, 1997-2004), where they collaborated as story editors and occasional script writers, only to move on again and find their momentum tempered by the quickly cancelled "Sleepwalkers" (NBC, 1997). But by this time in his life, Gaghan's drug addiction began taking its toll. Having been arrested some 20-30 times over the years on various misdemeanor charges, Gaghan found himself staring death in the face on several occasions. He once tried to rob a crack dealer, only to have the tables turned when the dealer pulled a gun. Another dealer went so far as to put a knife to his throat. While those experiences were not enough to convince him to change course, Gaghan hit rock bottom when he discovered over the course of five days that all three of his heroin dealers had been arrested, leaving him high and dry. While locked in the bathroom contemplating suicide, Gaghan found the strength to call a friend who happened to be the only person he knew that had quit drugs. His reaching out marked Gaghan's start upon the long road to recovery.
Gaghan segued to the big screen with his first writing credit on the horror sequel "I Still Know What You Did Last Summer" (1998). He moved on to write "Rules of Engagement" (2000), an old-fashioned military courtroom drama directed by William Friedkin and based on an idea from former U.S. Navy Secretary James Webb. Though the film enjoyed some success, it was nothing compared to his second screenplay of that year. For "Traffic" (2000), helmed by Steven Soderbergh, Gaghan turned a six-hour British television miniseries from 1989 into an engrossing, multilayered, critically acclaimed examination of the seeming futility of the War on Drugs. Drawing from his own experiences as an addict, Gaghan wove together the strands of three separate stories on both sides of the Mexican-U.S. border: a relatively honest Tijuana cop (Benecio Del Toro) struggling to balance his professional loyalties with his personal ethics; a San Diego socialite (Catherine Zeta-Jones) who takes over her husband's drug smuggling business after facing the threat of losing everything; and an Ohio jurist (Michael Douglas) newly appointed as the nation's new drug czar, who finds himself fighting a war on drugs much closer to home when his teenage daughter (Erika Christensen) succumbs to addiction. Both richly complex and deeply intimate, "Traffic" struck a chord with both audiences and critics, becoming not only a box office hit, but also an Oscar winner, with Gaghan being rewarded with the Academy Award for Best Adapted Screenplay.
Gaghan was in demand following his triumph with "Traffic," particularly as a script doctor, which led to writing uncredited drafts for movies like "Black Hawk Down" (2001) and "Phone Booth" (2003). He made his directing debut with the thriller "Abandon" (2002), crafted from his script about a reckless college student (Charlie Hunnam) whose disappearance leads a detective (Benjamin Bratt) to conclude something more sinister has happened. He moved on to write "The Alamo" (2004), an overinflated endeavor about the famed battle during the Texas Revolution that earned considerable critical scorn en route to becoming one of the biggest box office flops in cinema history. After receiving story credit on the teen-themed melodrama "Havoc" (2005), Gaghan assumed the director's chair for the second time for "Syriana" (2005), another complicated, multi-character exploration of a politically charged subject: this time the behind-the-scenes machinations over Middle Eastern oil. The result was an intriguing exploration of the issue through various points of view, including a burnt-out CIA agent (George Clooney) abandoned by the government he served; an idealistic analyst (Matt Damon) who becomes obsessed with helping an oil-rich nation develop after the death of his son; and a canny attorney (Jeffrey Wright) investigating the propriety of an oil deal. The result was another critically acclaimed hit that earned Gaghan a nomination for Best Original Screenplay at the Academy Awards. After several years removed from feature filmmaking, Gaghan returned to television as the creator of "S.I.LA." (NBC, 2011- ), a procedural that followed the intertwined worlds of politics, law enforcement and crime in contemporary Los Angeles.
Name | Role | Comments |
Tom Hague | Father | |
Betty Hague | Mother | |
Gardner Gaghan | Son | born c. April 2000 |
Michael McCraine | Companion | met during his recovery process from drug addiction |
Name |
Kentucky Country Day School |
Notes |
Gaghan had his short story, "The Year With No Winter", published in The Iowa Review in 1990. |
On his upbringing in Louisville, Gaghan (who admits to having "an addictive personality"), told the Los Angeles Times (January 7, 2001): "It's a town where smoking cigarettes is jingoistic," he says, referring to the local tobacco industry. "It's a city that's all about booze, tobacco and horse racing. . . . "In Louisville, there are a lot of euphemisms. I remember when an aunt or an uncle would disappear for two weeks, we were told, they were 'taking the waters,' which I later learned meant they were drying out somewhere. It was a hard-drinking environment. In Kentucky, you learn how to drink bourbon." |
"People were asking me about where the movie came from, where I got the characters and situations for 'Traffic,' and I found myself starting to speak in code," he said. He would talk about research he had done in the drug culture, about unnamed acquaintances, but he never admitted the core truth: that a lot of it came from his own life. "Part of the recovery process is a commitment to truth, and I began to feel that I was not being truthful," he said. "The stigma and shame of drug addiction is part of what makes it difficult for people to raise their hand and ask for help, and I felt that by not being completely honest I was, in a way, perpetuating that stigma." --From The New York Times, February 5, 2000. |
Gaghan estimates that he had been arrested some 20 to 30 times for misdemeanor charges related to his addictions, including three D.U.I.'s. |
"I smoked crack in my office on the Universal lot, always with some heroin to even it out," he said. "I smoked crack in my office on the Fox lot. Oh God, what are people going to think when they read this? I will never work in this town again." --Gaghan to Rick Lyman, quoted in "The Screenwriter for 'Traffic' Says He Drew on His Past of Drug Use" in The New York Times, February 5, 2001. |
Affiliations |
")); |
")); |
")); |


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Attorney Jolie Davis of Cedar Key has been appointed to the Levy County RESTORE Act Advisory Committee by the Levy County Commission. The appointment was made after the advisory group recommended her appointment as an at-large representative to fill a spot that has been vacant for several months.
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Web 2.0 Expo Ignite wrap-up: Session two
Ignite finished strong with presentations from Justin.tv, RobotReplay, and Omnidrive.
Justin Kan of Justin.tv talked about how easy it is to promote your site or product with the right strategy. It also doesn't hurt to have a camera hooked to a laptop, with an EV-DO connection streaming every second of your life. Our previous Justin.tv coverage here and here. Surreal moment of the talk? Checking Justin.tv and seeing him talking to us. Creepy
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1990 1/2 oz Canadian Platinum Polar Bear (PF-69 UCAM NGC)
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We provide all our customers with a refund, return and/or exchange policy on everything we sell including all bullion and certified coins. If for any reason you have a problem, please feel free to call our offices. We will always do our best to accommodate you.
Platinum | Bid: $1,459.30 | Ask: $1,469.30 |
Volume Pricing
Product Description
Proof 69 Ultra Cameo by NGC! Mintage of only 2,629 coins!
Reverse shows a Polar bear walking. Obverse displays crowned Elizabeth II.
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Product ID: | 74025 |
Year: | 1990 |
Grade: | PF 69 |
Denomination: | 150 Dollars |


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Sam and Lissa's Blog 4-4
by Lissa Kreisler
posted Apr 4 2013 10:06AM
Retail therapy….apparently I'm big on this.
You too?
I never thought about it until Sam the other day said I seem to enjoy the shopping experience more than what I actually end up buying. Might be true if you look in my closet and see all the tags on things..
Glad to see this isn't only a female thing…A study that morning that 63 percent of women and about 39 percent of men shop to improve their mood…
But generally when we women need a lift we look for clothing buys or a steal of a deal as my daughter calls them. Men look for food. That cracks me up…when men go to the mall they're more concerned with getting something to eat than buying something..
But if we are "shopping":….next to clothing buys we look for shoes or accessories….while men are more likely to electronics, games or music.
Last time you went shopping for "therapy".
And what did you end up getting or should I say eating?
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Centro LB 960 Microplate Luminometer
BERTHOLD TECHNOLOGIES GmbH & Co. KG
The Centro meets all currently known requirements for a versatile, robust and sensitive microplate luminometer. The selected detector and the proprietary design of the optical sytem guarantee lowest...read more
Julie Hjelmhaug Status: See all reviews Member since 2012 Job Title: Technician Discipline: Neuroscience / Neurology Work Field: Academia / University Organization: Marquette University Read more » | 5.0 RATING:
"The Centro LB 960 is easy to program and user-friendly. It automatically generates a spreadsheet that can be exported to Excel. It has a small footprint so doesn't take up much bench space. Their customer service is excellent - you can always email a technical expert for help and their representative is very helpful." |
The Centro meets all currently known requirements for a versatile, robust and sensitive microplate luminometer. The selected detector and the proprietary design of the optical sytem guarantee lowest background and negligible crosstalk.
Any opaque microplate in either 96 or 384 well format can be measured. There is no need for any mechanical adjustment just select the plate type in the operating software.
The Centro can be equipped with plate heating for applications where the assay must be measured at elevated and constant temperature such as cell based assays.
Up to 3 independently controlled injectors with variable volume give entire freedom in the selection of assay type and assay sequence. The volume is adjustable from 10 to 100 µl – perfectly fitting the demands for reagent addition into 96 and 384 well plates.
3 modes each with variable speed of the integrated shaker to enhance mixing and optimise sample distribution before measurement in long term kinetics.
Centro LB 960 Microplate Luminometer Preferred Applications:
- Cellular luminescence
- Oxidative burst
- Calcium monitoring with Aequorin
- Adenylate Kinase assays
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Bruins Nation gets the work week started with the regular Monday morning Bruin Bites round-up of the various bits and pieces of news from around the UCLA-iverse.
Bruins Nation gets the week started with the regular Bruin Bites round-up of bits and pieces of news from around the UCLA-iverse, taking note of the various pieces surrounding the traditional media-generated faux "controversy" surrounding Justin Combs and the football scholarship he earned.
A note of support for Justin Combs, incoming UCLA recruit who has been smeared by traditional media in recent days even though he earned his scholarship to play football for Bruins the old fashioned way - working hard in the classroom and on the field.
Topics in Shoddy Journalism: Looking at the manufactured storyline and media criticism of Justin Combs accepting an athletic scholarship to play football at UCLA, the lies forming the foundation of this attack and the hypocrisy of picking on just P.Diddy's son.
UCLA released a statement Wednesday explaining that athletic scholarships are not based on finances and do not rely on taxpayers' money. The University of California school system is currently facing financial problems. "Unlike need-based scholarships, athletic scholarships are awarded to students strictly on the basis of their athletic and academic ability -- not their financial need," the statement read. "Athletic scholarships, such as those awarded to football or basketball players, do not rely on state funds. Instead, these scholarships are entirely funded through UCLA Athletics ticket sales, corporate partnerships, media contracts and private donations from supporters. "Each year, UCLA awards the equivalent of approximately 285 full athletic scholarships to outstanding student athletes. The scholarships are used by the UCLA Department of Intercollegiate Athletics to pay students' tuition and fees, as well as room and board. In this respect, UCLA is no different from the overwhelming majority of Division I institutions."
UCLA Football Signing Day Wrapup, Part 2: Bruins Nation looks at the Defensive commits.
This guy @JDior_ is really recruiting like no other this weekend.
— Trigga (@BryceTreggs) December 29, 2011
Bryce Treggs, the #1 WR in California and a Cal commit who is rumored to be considering UCLA now with Adrian Klemm leading his recruitment, tweeted this today: "This guy @JDior_ is really recruiting like no other this weekend." @JDior_ is Justin Combs, a Bruin commit who is clearly trying to bolster that UCLA recruiting class. Keep it going, Justin.
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Sexual Assault Survivors Answer The Question "What Were You Wearing When You Were Assaulted?"
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GAME PREVIEW: FGCU Set to Face Big Ten Foe Nebraska
1st | 2nd | Final | |
Nebraska | 26 | 25 | 51 |
Stats at a Glance | FGCU | NEB |
FG Percentage | .400 (18-45) | .400 (18-45) |
3P FG Percentage | .450 (9-20) | .292 (7-24) |
FT Percentage | .500 (5-10) | .615 (8-13) |
Offensive Rebounds | 5 | 9 |
Defensive Rebounds | 20 | 23 |
Total Rebounds | 25 | 32 |
Turnovers | 13 | 18 |
Steals | 11 | 2 |
Bench Points | 35 | 23 |
Statistical Leaders | FGCU | NEB |
Points | BROWN
- 14 | Talley
- 14 |
Rebounds | COMER
- 4 MURRAY - 4 | Ubel
- 11 |
Assists | COMER
- 5 | Spencer
- 5 |
Steals | HOLMES
- 3 THOMPSON - 3 FIELER - 3 | Ubel
- 1 Spencer - 1 |
Blocks | HOLMES
- 2 MURRAY - 2 BROWN - 2 | Diaz
- 5 |
FGCU (3-5, 1-0 A-SUN) at Nebraska (4-3)
DATE: Wednesday, Dec. 7, 2011
CITY: Lincoln, Neb.
SITE: Devaney Center (13,595)
TIP-OFF: 8:00 p.m. ET
LIVE VIDEO: www.BTN.com
TALENT: Josh Peterson (P-B-P)
Brandon Aksamit (Analyst)
LIVE AUDIO: www.FGCUATHLETICS.com
TALENT: Gary Sharp (P-B-P)
LIVE STATS: www.FGCUATHLETICS.com
SERIES: First Meeting
Still in search of its first road win under head coach Andy Enfield, FGCU makes its lone trip away from home in December when it heads to the mid-west to take on Big Ten foe Nebraska on Wednesday night at the Devaney Center. The Eagles opened a hectic start to the season with five road games in November, including a pair against BCS schools, but play a total of five games in December. FGCU carries the momentum of a 72-63 win in its Atlantic Sun opener against ETSU into their sixth-ever game against a member of the Big Ten. Junior SHERWOOD BROWN is coming off his second career 20-point game and now leads the team in scoring at 11.8 points per contest. No FGCU player has led the team in scoring or rebounding in back-to-back games this season.
All five of FGCU's road losses on the young season have been by 10 points or less and have come by a combined 21 points. The Eagles' five road opponents so far this season currently all have a winning record and a combined mark of 26-11. A pair of one-point defeats in Dallas against TCU (73-72) and SMU (65-64), and a three-point loss at Loyola Maryland (77-74) headline the heartbreaking losses. On the road, FGCU is shooting a respectable 44 percent from the floor and has out-rebounded all five opponents.
Wednesday night's game at Nebraska will mark the fifth straight year FGCU has taken on a member of the Big Ten - each year the program has been a member of Division I. The Eagles are 0-5 all-time against the Big Ten and prior to this season had opened the year at a Big Ten member twice.
In its first season as a member of the Big Ten, Nebraska is off to a 4-3 start under sixth-year head coach Doc Sadler. After starting 3-0 with a win at PAC-12 foe USC in double-overtime, the Huskers have dropped three of their last four, including the last two. Nebraska is led by a senior trio of guards and pair of talented junior big men that make up an experienced starting five. A get-to-the rim point guard, Bo Spencer leads Nebraska in scoring at 17.3 points per game. Since a six-point night to open the season, Spencer has reached double figures six straight games, leading the team in scoring five times, highlighted by a three 20-point outings. Last game at Creighton, Spencer, a transfer from LSU, poured in 29 points on 10-of-16 from the floor against the Blue Jays. Junior Jorge Brian Diaz is second on the squad in both scoring (11.6) and rebounding (4.9), standing at 6-foot-11. A well balanced team, Nebraska shoots a solid 45 percent from the floor and 77 percent from the free throw line, commits just 13.9 turnovers per game and holds a +4.4 margin on the boards per game.
On March 31st, the FGCU men's basketball program got a new look for its 10th season in program history when ANDY ENFIELD was named head coach. Enfield, who spent the previous five years as an assistant with Florida State, is the second head coach in FGCU's brief history. While at FSU, Enfield was a part of two teams that advanced to the NCAA Sweet Sixteen and back-to-back clubs that lead the NCAA in defensive field goal percentage.
Three different FGCU players are averaging double figure points on the young season with another is just two-tenths of a point under the double-digit mark. The Eagles are one of six teams in the A-Sun with at least three double figure scorers. Seven different players have reached double figures in a game, while four different players have led the team in scoring, including three off the bench. Looking further, no player has led FGCU in scoring or rebounding in back-to-back games, while the same players has led the team in the two previously mentioned categories twice. Five players are playing 20 or more minutes per game, while nine players are above 13 per contest.
First-year head coach ANDY ENFIELD has used five different lineups through eight games trying to find the right combination with his young team. Nine different players have started at least one game, while four freshmen have earned a starting nod.
Highlighted by his first career double-double at Miami and a recent 20-point outing against ETSU, junior SHERWOOD BROWN has carried over a strong finish to his sophomore campaign into this season. Brown has reached double figures four times, leading the team in scoring (11.8) and tied for second in rebounding (5.5) - figures that rank 13th and 15th in the A-Sun, respectively. Sparked by a career-high 26 points in last year's season finale at USC Upstate, Brown finished last February (10 games) with a 11.2 scoring average - more than four points above his season mark. Brown reached double figures in each of the final four games, averaging 18.3 points while leading the team in scoring three times.
Through eight games, FGCU owns a 225-155 advantage in bench points, good for a +8.8 margin per game. The bench has supplied a double figure scorer in six games, including the team's leading scorer on four occasions, while supplying 25+ points six times as a unit. At SMU, sophomore CHRISTOPHE VARIDEL poured in 20 points on 6-of-7 from three-point land, while junior SHERWOOD BROWN'S 19 points against Ave Maria to account for the top two efforts off the bench. At Loyola Maryland, FGCU received a season-high 44 points off the bench, highlighted by a game-high 17 from Varidel and BERNARD THOMPSON.
A big part of the early success of the FGCU bench has been the performances by freshman BERNARD THOMPSON and sophomore CHRISTOPHE VARIDEL off the pine. Both have also been in the starting lineup, but have turned in season-highs off the bench. Thompson has reached double figures all three games off the bench, averaging 14.7 points while shooting 53 percent (16-30). Varidel's 11.0 points per game average off the pine is nearly four points better than his average in the starting five. Varidel poured in 20 points at SMU and 17 at Loyola Maryland to lead the team in scoring both times.
FGCU's freshmen class has wasted little time making an impact, accounting for 45 percent of the scoring, 33 percent of the rebounds and 68 percent of the assists. Combo guard BERNARD THOMPSON and point guard BRETT COMER rank second and third on the team in scoring at 11.3 and 10.1 points, respectively. Comer is the team's top assist man with 5.4 helpers per contest, a mark that ranks second in the A-Sun. Thompson's 11.3 points are second among all freshmen in the A-Sun and are joined by 5.5 rebounds per game. Thompson has scored in double figures a team-high six times, while Comer has done so in four games and both in the same game on four occasions. The duo was joined in double figures by classmate FILIP CVJETICANIN in the win over Prairie View A&M. DANTE HOLMES is the final member of the freshmen quartet that is having a big impact, averaging 6.3 points in 19 minutes per game.
Highlighted by three second half performances of 15 points by three different players, FGCU has overcome first half deficits in five of its games by averaging 38.5 points over the final 20 minutes while limiting its opponents to 32.9. Freshman BRETT COMER has been one of the catalysts to the second half turnaround, averaging 7.3 points over the span while passing out 27 assists that have led to 68 more points, giving him a hand in 41 percent of the points. As a team, FGCU is shooting 51 percent (109-213) in the second half, including 34-of-78 from three-point land. At Miami, FGCU tied a program D-1 record for second half points given up by limiting the Hurricanes to 18 points on 4-of-24 from the field. At Loyola, the Eagles scored a season-high 50 second half points.
Sophomore CHRISTOPHE VARIDEL is starting to find his stroke that helped him finish fifth in the nation among all freshmen in 2010-11 with 78 three-pointers. Varidel has made 14 of his last 23 three-point attempts to move into second in the A-Sun in three-point percentage (.514) and tied for third in threes per game (2.4). The Versoix, Switzerland native has made three or more treys in a game four times this season, including the last two games. He has also reached double-digits three times.
Ranking among the leaders in the Atlantic Sun Conference in four statistical categories, freshman BRETT COMER is off to a fast start early in the year. Highlighted by a 10-assist effort against Prairie View and ETSU, Comer is second in the A-Sun and fifth among all freshmen nationally in assists per game (5.4). He has reached double figures in four games, resulting in 10.1 points per game, good for 29th overall and fifth among freshmen in the A-Sun.
Coming off a season in which he played just 84 total minutes, redshirt junior EDDIE MURRAY is thriving under the guidance of first-year head coach ANDY ENFIELD. Armed with athleticism and leadership, Murray is providing a youthful roster with career-highs of 6.5 points and 3.8 points per game. The Fort Myers product is shooting a scalding 68 percent (21-31) from the floor over 19 minutes per game. Murray has started the last two contests, averaging nine points and four boards.
Despite lacking a ton of size, FGCU has out-rebounded seven of eight opponents this season, owning a +3.0 margin on the boards. The Eagles are also averaging double-digit offensive caroms (11.9) that have helped them score 20+ points in the paint each contest and 106 over the last three. Over two games in Maryland, FGCU pulled down a season-best 17 offensive rebounds twice that led to another season-high in points in the paint (42) at Maryland. Four different players have double figure offensive rebounds on the season.
Copyright ©2014 FGCU Athletics. All Rights Reserved. | www.FGCUAthletics.com |


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Whaaat?: Sand People Like Scooby Snacks?
In a mash-up of universes that's about to make my head explode, it turns out Tusken Raiders love Scooby Snacks. And speaking of which -- I'd like to see Scoob and the gang try pulling THAT dude's mask off. Ruh-roh is right -- you gonna die!
Sand People like Scooby Snacks [tk8247's deviantart]
Thanks to sham, who only tried Bantha fodder once and didn't like it.
There's an Instructables out there that teaches the do-it-yourselfer how to make their own Boba Fett helmet out of cardboard. You know, so you can mix universes and play PEW PEW with this kid in his backyard. Unfortunately, no matter how good your helmet turns out, you're sti... / Continue →
This is a shot by photographer Rizwan Baig from the recent London Film and Comic Con featuring a Stormtrooper who's had his mask laser-blasted and part of his skull exposed. Pretty brutal. Also, maybe it's just me, but doesn't the skull seem a little small for the mask? Now ... / Continue →
This is a $55 Princess Leia hoodie available from Hot Topic with attached hair buns. Now I know what you guys are thinking, "But I can't wear that -- I'm a DUDE." No worries bro, I've got you covered. Just paint some big some big-ass eyeballs on the sides of the hairbuns and... / Continue →


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Work your way through the maze from start to finish picking up the two keys to unlock the doors at the opposite end. Be wary though, monsters are lurking everywhere and blasting bombs, evade them at all costs!


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Come Out & Play
Whether your looking for team bonding, want to reward folks for their hard work or are itching to just let loose and have a ball, Whistler Blackcomb has off-mountain activities to suit your every whim.
In fact, there are so many to choose from, you might need a little help narrowing your choices. That's why we've put together this list of what we think are 10 of the best.
You don't become the #1 Mountain Resort in North America without offering some of the best skiing and boarding in the world. And with lessons and terrain for all skill levels, no one has to miss out on the fun.
The journey between the two Mountains provides a 360-degree window into Whistler Blackcomb's alpine environment, its surrounding peaks, and changing seasons, but sightseeing is just the start of your adventure.
See DetailsExperience the exhilaration of flying as you glide across a network of ziplines suspended high above Fitzsimmons Creek and through the ancient coastal rainforest. Perfectly for all ages, too.
See DetailsSnowmobiles are fast, powerful and undeniably fun. They can also take riders deep into the backcountry to places no other mode of transportation can go. There are tours available for all ages and levels of riders, from veteran sledders to complete beginners.
See DetailsThis ancient way to travel through snow is now one of the most popular wintertime activities we offer. It's fun, rewarding and some of the best exercise you can have. Day and nighttime tours available.
See DetailsThis isn't the tobagganing you remember from your childhood. More like multi-lane, high speed extreme tubing that just may be one of the best memories of your time here.
See DetailsA horse-drawn sleigh ride is a totally unique way to tour Whistler's pristine backcountry, and a sumptuous fondue dinner the perfect way to complete this true winter adventure.
See DetailsA 3-hour tour of Whistler combined with a four-course meal. The twist? Each course is provided by a different restaurant and paired with a BC wine (optional). The perfect way to explore Whistler's food scene.
See DetailsWith exclusive rights to terrain that includes 173 glaciers and 475 runs, Whistler Heli-Skiing has what it takes to go the extra distance. Packages are available for everyone from intermediate skiers and boarders to seasoned experts. Transform your ski holiday into a dream one.
See DetailsA Guided private program with a Guest to Instructor ratio of 5:1. Having a worldrenowned Snow School Instructor on hand is the perfect way to learn the Mountain, gather new tips and skills, acquire confidence, and form bonds that will last a lifetime.
See DetailsThe world record-breaking PEAK 2 PEAK Gondola is a breathtaking, 4.4-kilometre journey to infinite possibilities.
See DetailsWith the highest, longest and most exciting ziplines around, Ziptrek offers an entertaining combination of high-wire adventure and ecological exploration.
See DetailsWith the highest, longest and most exciting ziplines around, Ziptrek offers an entertaining combination of high-wire adventure and ecological exploration.
See DetailsSummer brings whitewater fun to Whistler resort. The surrounding peaks and rugged coastal valleys are natural ingredients for great river running.
See DetailsOver 4,900 vertical feet of lift-serviced gravity fed, adrenaline fueled descending trails. Something for every level of rider.
See DetailsDine at 6,000 ft on Whistler Mountain with mouth watering BBQ chicken and pork, fresh corn on the cob, oven baked biscuits, and select desserts.
See DetailsBook your tee times online or by phone with Central Reservations for Whistler Blackcomb! Whistler is truly North America's finest four-season
See DetailsDiscover Whistler's best dining in one enjoyable evening. We visit 4 amazing restaurants to sample delicious food paired with fine BC wines.
See DetailsInvigorate and cleanse your body and mind to attain greater health, balance, peace of mind and vitality.
See DetailsThis guided horseback trail ride takes you through west coast forests, along sandy river beaches, and the through grassy meadows of Mt. Currie.
See Details