text:
Emily's Profile
Welcome to EmDashPaperCo.etsy.com!
I am an English BA and MA, an avid reader, a lover of the written word in all its forms. My craft centers on the visually pleasing arrangement of words on a page, incorporating my love of words both as tools for communication and as works of art in themselves.
I'm very environmentally aware when I create by using recycled and responsibly-sourced papers, and shipping orders with recycled or biodegradable materials.
"What does your name mean??"
I am EMily Poe DASH Crawford and "the Dash" (Winston-Salem) is my home. The em dash (—) is also a reference to my grammatical / literary background. I'll miss Sparrow Nest Script, but I'm excited about the new directions Em Dash will allow my business to take!
- Female
- Born on April 15
- Joined May 4, 2011
Favorite materials
brown kraft paper, heavy cardstock, moleskine cahier notebooks, white ink, metallic inks, patterned papers
Treasury lists
See more-
- Emily
- Winston-Salem, NC, United States
Hand Lettering by Emily Poe-Crawford


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Biography (Critical Survey of Poetry: American Poets)
Mary Oliver's poetry bears witness to a difficult childhood, one in which she was particularly at odds with her father, a teacher who died without their being reconciled. Her childhood experience profoundly influenced her poetry, as the body of her work develops a journey of healing from the effects of trauma. In "Rage," she writes of a childhood incest scene, detailing its damaging and continuing effects on daily adult life. Her poetry is remarkable for its limited focus on herself as a personality while showing a path out of terror and sorrow to acceptance, safety, joy, and freedom.
Oliver attended Ohio State University for one year, then transferred to Vassar College, but left after a year. She has taught at several institutions: the Fine Arts Workshop in Provincetown, Massachusetts; Case Western Reserve as Mather Visiting Professor; Sweet Briar College in Virginia as Banister Writer-in-Residence; and Bennington College in Vermont as Catherine Osgood Foster Chair for Distinguished Teaching (1996-2001).
Biography (Poetry for Students)
Mary Oliver was born September 10, 1935, in Maple Heights, Ohio, to Helen and Edward Oliver (a teacher). Oliver has described herself as a...
(The entire section is 295 words.)
Biography (Poetry for Students)
Mary Oliver was born in Cleveland, Ohio, in 1935. Her father was a teacher and her mother a stay-athome mom. Oliver knew early on that she...
(The entire section is 476 words.)

subset: commoncrawl


text:
Glenn Gamboa 3/10/14 Lorde plays powerful show at Roseland Ballroom
Lorde may say she'll never be royal, but her Roseland Ballroom show Monday night suggested ... Read more »
Glenn Gamboa 3/4/14 Paul Simon, Sting click at Madison Square Garden
It turns out Paul Simon and Sting have more in common than we thought. ... Read more »
Glenn Gamboa 2/24/14 Kanye ends 'Yeezus' tour on LI
Kanye West's "Yeezus" tour wrapped up at Nassau Coliseum with a show packed with surprises. ... Read more »
Glenn Gamboa 1/19/14 Jay Z shows dance moves at Coliseum show
His "Magna Carta" raps came to life Sunday at the Nassau Coliseum. ... Read more »
Glenn Gamboa 11/8/13 Real talk about those 'insane' Billy Joel ticket prices
Tickets for Billy Joel's New Year's Eve concert at Barclays Center go on sale Monday ... Read more »
Glenn Gamboa 11/6/13 Ovations at Stand Up for Heroes benefit at MSG
Bill Cosby was in the middle of explaining the difference between a "beating" and a ... Read more »
Glenn Gamboa 10/29/13 Drake smooth as silk at Barclays Center
Drake's live show has grown by leaps and bounds from his early days. ... Read more »
Glenn Gamboa 10/18/13 Biegel to play Sedaka at Molloy College
Jeffrey Biegel has had his piano performance of Liszt praised by Leonard Bernstein. His interpretation ... Read more »
Glenn Gamboa 10/4/13 LI's John Sullivan releasing new Americana CD
John Sullivan is planning something new for his 50th birthday Thursday. The Garden City singer-songwriter, ... Read more »
Glenn Gamboa 9/20/13 Ryan Star fans finance new music
Ryan Star, energized by the success of his self-released "Animals" EP, is now looking to ... Read more »
Glenn Gamboa 9/13/13 LI Sound, Paramount climbs on Pollstar
The Pollstar list of the world's busiest clubs is packed with legends -- including Washington, ... Read more »
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Have any type of fun. Go out and play. Gather with friends. Do something that isn't productive. Do whatever you can to separate yourself from things you may want to get done but are getting frustrated with. Laugh, laugh, and laugh some more.
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greeting DIYcity users!
my name is Nick Normal and I'm an artist, maker and educator based in Long Island City, Queens, NY.
I wanted to let everyone on this list know that Maker Faire is coming to New York City - and by extension the East Coast! - for the first time later this year, on September 25th and 26th. There's currently an open call for Makers to submit proposals - the deadline is August 15th.
Maker Faire is the world's largest DIY festival - a blend of Art, Technology and Science, combined with family-fun, participation, robots, craft and do-it-yourself ethics.
I'm helping recruit Makers and we're looking for projects involving open-source code, robots, DIY makers, engine-hacks, solder fiends, hobbyists and enthusiasts, fixer-uppers, food makers, etc.
if you DIY we want you involved!
Here's the link to the open call:
World Maker Faire NYC Open Call
or if you have any questions, comments or conerns you can contact me. My email and phone are below. I look forward to hearing from all you Do It Yourselfers!
Nick Normal
artist, maker, librarian, diplomat
917.225.7032 (mobile)
email@example.com (email, gchat, etc.)
DIYcity folks,
Work with us to take our Placemaking processes and tools online. After the imminent re-launch of our website, we are looking at developing web 2.0 and 3.0 applications to support community-driven, place-based planning efforts.
The Job Description:
Ethan Kent
Vice President
Project for Public Spaces
700 Broadway New York, NY 10003
T (212) 620-5660 x 318 F (212) 620-3821
Reposted announcement from Philip Ashlock, The Open Planning Project:
I'd like to invite you to take part in the initiative to bring cities together in the pursuit of sharing technology and standards for 311 services. Please forward this to other interested parties.
To attend or see the current list of attendees including other cities: http://open311.eventbrite.com/ (So far the 311 teams from NYC, D.C., Toronto, Columbus, and other cities are attending)
On October 24th, The Open Planning Project will host Open311 DevCamp at their NYC office. Please register to attend either in person or remotely via Eventbrite (it's free). This is a DevCamp style un-conference to coordinate a standard specification for 311 services. Washington D.C's 311 API will be a major case-study for developing a more universal 311 API. In general, this DevCamp will be an opportunity to discuss and develop what's needed to make 311 services more accessible and for cities to share knowledge for mutual benefit. The event is intended for developers, project managers, and policy makers involved with 311 services. We encourage those involved with 311 services from all cities to take part. If you cannot attend in person, please sign up as a remote attendee and we'll provide you with information about how to connect to the DevCamp remotely.
Please register at http://open311.eventbrite.com
The wiki page for the event is http://wiki.open311.org/Open311DevCamp
Ultimately this conversation will lead to a standard specification for 311 services, but the very first goal is to create an environment for knowledge-sharing and best practices.
On the same day there will another event in NYC that focuses on coordinating open technology for mobile devices and we plan to coordinate with that event as well: http://openmobilecamp.eventbrite.com/
I hope you can be involved or can forward this to the most relevant person in your city. Please let me know if you have any questions.
Philip Ashlock
Philip Ashlock
The Open Planning Project - http://www.openplans.org
email@example.com | @philipashlock | (360) 389-2741
My name is Alec Resnick, and I'm working to start up an open community research and education lab with a focus on educational outreach and data visualization called sprout. You can check out a placeholder page at http://thesprouts.org -- that'll be changing pretty significantly in the next couple weeks.
But, that's kinda beside the point of this email. While talking to some potential partners for the nonprofit I'm starting, I met with some people at the Executive Office of Transportation (EOT) in Boston. They're really keen to bring together a handful of developers who might be interested in working with them to develop applications on top of the data they're beginning to collect and open up (stuff like traffic cams, traffic flow, MBTA schedules, etc.) A few other hackers will be getting together with the Josh Robin and Chris Dempsey from the EOT to talk about what developers would like to see from the EOT and to discuss the potential for hacking on the data the EOT is opening up.
If you're interested, feel free to comment here or shoot me an email at alec::at::thesprouts.org. The EOT was hoping to meet with developers sometime next week, but they're flexible. . .
Following yesterday's presentation and working group session with the City's IT Manager at OpenWebVancouver09, Luke Closs has setup a Google Group specifically focused on the Open Data component of Andrea Reimer's "Open Data, Open Standards, Open Source" motion.
You can join the group at http://groups.google.ca/group/vancouver-data/
Just as the federal government begins to provide data in Web developer-friendly formats, we're organizing Apps for America 2: The Data.gov Challenge to demonstrate that when government makes data available, it makes itself more accountable and creates more trust and opportunity in its actions. The contest submissions will also show the creativity of developers in designing compelling applications that provide easy access and understanding for the public, while also showing how open data can save the government tens of millions of dollars by engaging the development community in application development at far cheaper rates than traditional government contractors.
After I saw the huge success of @TamaleTracker I thought, we can't be the only people who could benefit from a real time messaging service like this. Why not utilize what Twitter has provided for me, a common data source that people are becoming more and more familiar with, combined with this technology and make it available for anyone who wants to create their own tamale tracker or other service to aggregate their followers content. So I created the Spotd service to do just that.
Spotd and its a free service that listens for @replies sent to a Twitter account and then relays those messages through itself. It's the same functionality as the Tamale Tracker but this can be used for anyone and anyone can set one up. Simply register a Twitter account to the Spotd service and any reply sent to the account will be retweeted.
In addition to being a bot for Twitter accounts, Spotd also is my try at creating a real time communication device for cities and towns across the world. I spend a lot of time walking around Chicago and see interesting things happen all the time - people getting arrested, car accidents, buildings on fire, bank robbery, protests and other news-worthy things. I tweet about them, but I wanted to create something to give people a common source of communication throughout their city to stay on top of things that are happening right now without having to wait for major media outlets to cover them. That's where the Spotd news service comes in, it is an aggregated, user-submitted news feed for interesting things going on - so far, I created accounts for @SpotdChicago, @SpotdLA, @SpotdSF and @SpotdNYC; with more to come and any user can create their own Spotd news service for their own city.
I hope you can see the value in this as much as I do, if you'd like more information, have any suggestions or would like to help me work on this, please feel free to contact me.
- Clint
Sorry to post to two groups, but I think this essay and interview with Usman Haque, creator of Pachube, is worth general discussion as well as posting in sensor networks. Interesting that Bruce Sterling was involved as "visionary adviser".
Hey all,
The possibilities of this forum are practically limitless - so let's start exploring them! While we haven't had a physical meet up (yet) this space can be a starting point for Twin Cities specific DIY ideas. Please, respond to this thread with
-what the ideal DIY TC would look like
-urgent (TC specific) issues you want to tackle with DIY tech
-next steps in addressing those issues
Also: how can we spread the news about this project? Like any forum, it depends on a quantity of quality contributors - spread the word!
The MetLife Foundation and the Local Initiatives Support Corporation are partnering for the eighth year to recognize, sustain, and share the work of innovative partnerships between community groups and police that promote neighborhood safety and revitalization.
Awardees will receive cash grants ranging from $15,000 to $25,000 each. Case studies about award-winning partnerships will be disseminated throughout the community development and law enforcement industries. Previous winners have used award money to pay for special patrols, trainings, and equipment for officers.
Grants will be awarded in two categories. Neighborhood Revitalization Awards (six grants of $15,000 to $25,000 each) celebrate exemplary collaboration between community groups and police that result in crime reduction as well as economic development activity, including real estate development, business attraction, and job growth. Special Strategy Awards (six awards of $15,000 each) will be given to community and police partners that have achieved significant accomplishments in applied technology, aesthetics and greenspace improvement, diversity, inclusion and integration, drug market disruption, gang prevention and youth safety, or seniors and safety.
Further information and a link to the full Request for Proposals is available at the LISC Web site.
[source: http://foundationcenter.org/pnd/rfp/rfp_item.jhtml?id=240900017


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Definitions Mac
From £1.05 per week
- Price
- £80.00
- In Stock
- Delivery
- Next day delivery available
1 reviewDefinitions Zip Front Mac
An urban take on the classic mac
This zip front mac by Definitions is an essential part of your spring wardrobe.
This coat is the perfect cover-up for the new season – light enough to wear on a sunny day and practical for those April showers. Combining classic storm flaps and belt fastenings with zip detailing gives this classic piece street style edge.
Wear this mac with a floral day dress, ballet pumps and a structured tote bag for a moment of classic style.
Whatever you do, do it in style
Useful info:
- Mac coat by Definitions
- Zip front fastening
- Belt tie feature
- High shine trims
- Zip back storm flap
- Three front pockets
- Button fasten cuffs
Little Mistress Waterfall Jacket
From £1.55 per week
- Was
- Was £45.00
- Now
- Now £31.00
- Save £14.00
- In Stock
- Delivery
- Next day delivery available
1 reviewLittle Mistress Cropped Waterfall Jacket
Every girl needs a chic little cover up this spring and this cropped waterfall jacket by Little Mistress is the perfect pick, day or night.
The cropped length of this cover up is ideal for a light daytime layer or a cute addition to your evening wardrobe on chilly spring nights. The waterfall style is worn open for an effortlessly laid back, yet glam piece of styling. Three-quarter sleeves make this jacket a transitional layer that will last from season to season, while the rolled cuffs add to the relaxed appeal.
Wear this waterfall jacket over a semi-sheer blouse, a pair of printed sateen trousers by Little Mistress and patent stiletto heels for a day-to-evening outfit.
Useful info:
- Cropped waterfall jacket by Little Mistress
- Three-quarter sleeves
- Rolled up cuffs
Voi Jeans Hooded Padded Jacket - Black
From £0.67 per week
- Was
- Was £74.00
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- Now £51.00
- Save £23.00
- In Stock
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- Next day delivery available
0 reviewVoi Padded Jacket - Black
Keeping your urban style this padded jacket by Voi gives it an updated twist ready for spring.
Medium weight padding ensures this jacket keeps you warm on chilly spring days, while being light enough not to warm you up too much! A faux fur trim hood adds a hot piece of styling that this season loves and ribbed cuffs help to keep cold air out.
Wear this padded jacket with a Voi jumper and their combat cuffed jeans. Add a pair of Converse for a laid back look.
Useful info:
- Padded jacket by Voi
- Faux fur trim hood
- Ribbed cuffs
- Medium weight padding
- Pockets to the front
- Zip fastening detail
- Logo and lining to the hood
South Button-up Jersey Blazer
The blazer is an essential this season, adding a polished finished to any outfit in an instant. With a single button to the front this blazer is neat, chic and understated – ideal for a day to evening outfit.
In jersey fabric this blazer has a soft casual feel. The turn-up cuffs show off a contrast woven half lining for an eye-catching finish. The cut of this blazer makes it an ultra flattering final layer, lending a smart feel to your look.
This piece is exceptionally versatile. From skinny jeans to a pencil skirt, this blazer finishes your look with complete coordination. Wear with a simple white vest, skinnies and court shoes.
Useful info:
- Jersey blazer by South
- Button fastening to front
- Woven half lining to the inside
South Single Breast Mac
Add a sixties inspired spin to your casual looks in this ladies mac by South – the perfect every day cover up for this season.
A well-cut coat is an essential, perfect for staying dry and pulling a look together. This mac's retro cut gives your casual looks an air of sixties flair. Fully lined, it covers you comfortably as the button down front and oversize buttons conceal you from April showers. A buckled, belted middle nips you in, defining your waist and flaring to skim your lower half. With storm patch and an overlay to the back, this mac is packed with classic features making it a timeless piece you'll love for years.
Pair this mac with your favourite top, South Ella skinny jeans and Moda in Pelle Besty ankle boots for a sleek and chic everyday look.
Useful info:
- Mac by South
- Shoulder overlay to back
- Pocket to each side
- Single breasted
- Long sleeved
- Belted waist
- Storm patch
South Denim Jacket
From £1.50 per week
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- Was £35.00
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- Now £30.00
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- Next day delivery available
2 reviewsSouth Denim Button Cuff Jacket
This denim jacket by South is the perfect spring cover up – it'll see you stylishly through the season.
A denim jacket is an essential part of every chic girl's wardrobe– the iconic style of this piece works well with your casual look. Classic features like a button up front, denim fading and pockets give this design an authentic American heritage feel.
Wear this jacket over a colourful skater dress with ballet pumps and a printed scarf for a pretty daytime outfit.Useful info:
- Denim jacket by South
- Four pocket style
- Button up cuffs
- Button front fastening
So Fabulous Lightweight Quilted Biker Jacket (Available in sizes 14-32)
From £0.72 per week
- Price
- £55.00
- In Stock
- Delivery
- Next day delivery available
2 reviewsSo Fabulous! Quilted Biker Jacket
This quilted biker jacket by So Fabulous! will transform your casual wardrobe with its sleek design and edgy detailing.
This cover up will be your go-to piece this season – its classic design and biker highlights add instant oomph to any outfit. The flattering quilted fabric adds interest to this piece with its authentic look while the gold metal ware is a glamorous finishing touch.
Wear this jacket with So Fabulous! cigarette trousers, a jersey tee and studded heels for an effortlessly cool look.
Useful info:
- Biker jacket by So Fabulous!
- Quilted look fabric
- PU trim detailing
- Off centre zip fastening
- Gold popper detailing
- Side buckle fastenings
- Front facing pockets
- Worn length: 26 inches
South Military Jacket
From £2.45 per week
- Price
- £49.00
- In Stock
- Delivery
- Next day delivery available
2 reviewsSouth Oversized Military Jacket
Cool, chic and lightweight this military jacket by South has it all - it's the ideal choice for casual days when your outfit needs a statement piece.
Military is a trend that never goes out of fashion and this jacket will keep you amongst the fashion pack this season. Lightweight, it is the perfect pick for chilly spring days and breezy summer evenings. Metallic trims add a touch of fun, while the belt detail nips in your waist for a gorgeous finish.
Wear this jacket over a casual T-shirt and a pair of South trousers with ankle boots for a relaxed look.
Useful info:
- Military jacket by South
- Oversized
- Metallic metal trims
- Front pockets and functional belt
Superdry Pop Zip Hooded Arctic Windcheater
From £1.05 per week
- Was
- Was £87.00
- Now
- Now £80.00
- Save £7.00
- In Stock
- Delivery
- Next day delivery available
0 reviewSuperdry Hooded Windcheater - Black/Punk Pink
This hooded windcheater by Superdry is soft and warm ensuring you're prepared for whatever the weather throws at you this season.
The classic black hue contrasts with the punk pink trims adding edgy feminine attitude to your look. With the triple zip fastening, you'll be able to cheat the wind by keeping the cold air out and the warm air in. A contrast fleece lining to the body and hood acts as an insulator to help keep you warm and snug, while ribbed cuffs and collar shield your face and arms from the wind. This coat also features back and shoulder embroidered logos for a classic Superdry finish showing off their Japanese influences.
Wear this jacket as part of your everyday casual style. Complete your laid back look by wearing it over a Superdry tee, hoodie and jeans.
Useful info:
- Women's windcheater from Superdry
- Ribbed collar and cuffs
- Triple zip fastenings to front
- Contrast fleece lined body and hood
- Embroidered front and back logos
- Length: 24 inches
So Fabulous Denim Jacket (Available in sizes 14-32)
From £1.75 per week
- Price
- £35.00
- In Stock
- Delivery
- Next day delivery available
3 reviewsSo Fabulous! Indigo Wash Denim Jacket
Channel an 80s inspired style with this denim jacket by So Fabulous! This ladies jacket is perfect for wearing with statement prints and patterns and we love the indigo wash for a flattering style.
With a button-through design this So Fabulous! denim jacket is great for layering - from shift dresses to tunics, we'll be wearing it over our favourite autumn pieces for a nod to the 80s. This ladies denim jacket also features chest pockets for a touch of detail and the floral print to the back neck gives it a fun finish.
Wear this So Fabulous! denim jacket with a printed floral shift dress and patent heels. Pare down with slim fit trousers and a longline knitted tunic top.
Useful info:
- Denim jacket by So Fabulous!
- Button-through front; long sleeves
- Worn length: 20 inches
Savoir Crepe Short Length Jacket
From £1.95 per week
- Was
- Was £44.00
- Now
- Now £39.00
- Save £5.00
- In Stock
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3 reviewsSavoir Crepe Short Length Jacket - Black or Coral
A chic cover up this short length jacket by Savoir is the ideal piece for special occasions that run on into the night.
Available in two colours this jacket is kept classic in black and given a summer update in coral. Hook and eye fastenings perfect the fit, while structures seams to the back and front panels add shape. Three-quarter sleeves keep this piece looking summer ready, while the rounded hem is a beautiful finish.
Ladies tailored fashion Rochette crepe jacket. Can be worn as a smart ladies workwear jacket with smart trousers or as a ladies occasion jacket. Wear with skirt (cat number 3VEAV), bootcut trouser (cat number 3VEAU) or straight leg trousers (cat number 3VEAT) for a smart formal ladies suit. Long line jacket also available (cat number 3V7EJ). Petite sizes also available in Jacket (3VLUM), Bootcut trouser (3VLUA), straight leg trouser (3VLUF) and skirt (3VLUE).
Useful info:
- Jacket by Savoir
- Short length
- Rounded edged hem
- Small split to sleeves
- Hook and eye fastening
- Exposed stitching to lapels
- Structures seams for added shape
- Two front pockets with stitched detail
- Worn length 21inches
South Core PU Trim Parka Jacket
This season, we're smitten with army inspired colours and this parka jacket by South is a great final layer that keeps you cosy, snug and stylish.
This jacket features a PU trim for a striking contemporary finish. The detachable faux fur lining to the hood is soft and pretty while the drawcord waist gives this piece shape. This parka jacket is lightly padded to the inside for added comfort that keeps the cold at bay, and the high quality fabric promises a jacket that outlasts the season.
In versatile khaki this parka jacket is a stunning pick. We love the pockets and the length makes it perfect for pairing with skinny jeans or leggings. On cold days, wear this parka with a long sleeved jersey top.
Useful info:
- PU trim parka jacket by South
- Detachable faux fur trim to the hood
- Lightly padded for added comfort
- PU trim pockets; drawcord to waist
- Also available in a tall and petite fit
- Worn length: 39 inch


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Antibiotic Prophylaxis in Laparoscopic Cholecystectomy
This study is currently recruiting participants.
Verified June 2013 by University of Roma La Sapienza
University of Roma La Sapienza
Information provided by (Responsible Party):
Erasmo Spaziani, University of Roma La Sapienza
ClinicalTrials.gov Identifier:
First received: June 13, 2013
Last updated: June 25, 2013
Last verified: June 2013
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
The trial aims to assess the value of two-regimen antibiotic prophylaxis versus placebo in elective laparoscopic cholecystectomy.
Condition | Intervention | Phase |
Cholelithiasis |
Drug: Ciprofloxacin Drug: Ampicillin-sulbactam Drug: Placebo |
Phase 4 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor) Primary Purpose: Treatment |
Official Title: | Ciprofloxacin, Ampicillin-sulbactam and Placebo Prophylaxis in Laparoscopic Cholecystectomy. A Randomized Controlled Study |
Resource links provided by NLM:
Drug Information available for:
Ampicillin sodium
Ampicillin trihydrate
Sulbactam sodium
Ciprofloxacin hydrochloride
U.S. FDA Resources
Further study details as provided by University of Roma La Sapienza:
Primary Outcome Measures:
- Surgical site infection [ Time Frame: 30 days after operation ] [ Designated as safety issue: No ]Surgical site infection defined according to the Centre of Disease Control (CDC) classification, recorded as 'yes' or 'no'.
Secondary Outcome Measures:
- Extra-abdominal infections [ Time Frame: 30 days ] [ Designated as safety issue: No ]Extra-abdominal infections defined according to the CDC classification, recorded as 'yes' or 'no'.
- Adverse events. [ Time Frame: 30 days ] [ Designated as safety issue: Yes ]Adverse events, defined as allergic reactions to antibiotics.
- Quality of life [ Time Frame: 30 days ] [ Designated as safety issue: No ]Quality of life measured with the 36-Item Short Form Health Survey
Estimated Enrollment: | 138 |
Study Start Date: | June 2013 |
Estimated Study Completion Date: | June 2014 |
Estimated Primary Completion Date: | June 2014 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Placebo Comparator: Placebo
Intravenous infusion of 0.9% Sodium Chloride 250 ml during induction of anesthesia and before laparoscopic cholecystectomy.
Drug: Placebo
Prophylactic placebo infusion before elective laparoscopic cholecystectomy
Active Comparator: Ampicillin-sulbactam
Intravenous infusion of 3gr ampicillin-sulbactam in 0.9% Sodium Chloride 250 ml during induction of anesthesia and before laparoscopic cholecystectomy.
Drug: Ampicillin-sulbactam
Prophylactic ampicillin-sulbactam infusion before elective laparoscopic cholecystectomy
Active Comparator: Ciprofloxacin
Intravenous infusion of 400 mg ciprofloxacin in 0.9% Sodium Chloride 250 ml during induction of anesthesia and before laparoscopic cholecystectomy.
Drug: Ciprofloxacin
Prophylactic ciprofloxacin infusion before elective laparoscopic cholecystectomy
Detailed Description:
All patients enrolled will be submitted to laparoscopic cholecystectomy. The primary aim of the trial will be to assess the role of prophylactic i.v. infusion of ampicillin-sulbactam, ciprofloxacin, and placebo to reduce the rate of surgical site infection.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- elective laparoscopic cholecystectomy;
- patients suffering from gallbladder stones,chronic cholecystitis, cholesterolosis, or gallbladder polyps.
Exclusion Criteria:
- acute cholecystitis;
- acute cholangitis;
- acute pancreatitis;
- pregnant or lactating women;
- antibiotic allergy;
- antibiotic therapy within 48 hours to 7 days prior to surgery;
- clinically active infection at the moment of surgery;
- evidence of common bile duct stones;
- contraindications for laparoscopic cholecystectomy;
- no other additional procedure;
- indication of obligatory antibiotic prophylaxis because the medical condition was different from biliary disease (immunosuppression, corticoid use, etc).
- patients unable to give informed consent.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01888822
Contact: Marcello Picchio, MD | +39-0773695488 | email@example.com |
Italy | |
Sapienza University of Rome- Polo Pontino | Recruiting |
Terracina, Latina, Italy, 04019 | |
Contact: Erasmo Spaziani, MD, PhD +39-0773708759 email@example.com | |
Contact: Annalisa Di Filippo, MD, PhD +39-0773708759 email@example.com | |
Principal Investigator: Annalisa Di Filippo, MD, PhD |
Sponsors and Collaborators
University of Roma La Sapienza
Study Director: | Erasmo Spaziani, MD, PhD | Sapienza University of Rome |
More Information
Keywords provided by University of Roma La Sapienza:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on March 09, 2014
Responsible Party: | Erasmo Spaziani, Professor, University of Roma La Sapienza |
ClinicalTrials.gov Identifier: | NCT01888822 History of Changes |
Other Study ID Numbers: | MarPic63 |
Study First Received: | June 13, 2013 |
Last Updated: | June 25, 2013 |
Health Authority: | Italy: National Monitoring Centre for Clinical Trials - Ministry of Health |
Keywords provided by University of Roma La Sapienza:
Laparoscopic cholecystectomy Prophylactic antibiotics |
Additional relevant MeSH terms:
Cholelithiasis Cholecystolithiasis Gallstones Biliary Tract Diseases Digestive System Diseases Gallbladder Diseases Calculi Pathological Conditions, Anatomical Ampicillin Anti-Bacterial Agents Sulbactam |
Sultamicillin Ciprofloxacin Antibiotics, Antitubercular Anti-Infective Agents Therapeutic Uses Pharmacologic Actions Antitubercular Agents Nucleic Acid Synthesis Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action |
ClinicalTrials.gov processed this record on March 09, 2014


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Published: Oct. 6, 2008
Updated: Mar. 21, 2011
Duke's James Nunley, MD, chair of orthopaedic surgery, leads an elite team of bone, muscle, and joint specialists.
James Nunley: Ankle replacements are actually extremely uncommon, with less than 3,000 done per year, compared to about 250,000 hip replacements each year. Not many doctors are trained in this kind of surgery.
At Duke, we have three leaders in the field, and we've probably done more ankle replacements in the last year than any other place in the United States. We were also instrumental in developing the techniques used for ankle replacement.
James Nunley: New prostheses developed in recent years are making ankle replacements a better option. In 1975, we fused hip joints to treat arthritis. Eventually, artificial hips were developed, which are now quite effective. The same thing is happening with the ankle.
We started off fusing the ankle joint, but new and better prostheses mean we can do replacements for more patients. Today, we can do things we couldn't do three years ago.
James Nunley: When the pain interferes with lifestyle, you should consider an ankle replacement to improve function and to relieve pain -- just as for the hip. Many people live with the pain because they don't know what's possible.
James Nunley: In orthopaedics one of our main research labs focused on translational medicine is studying methods of replacing cartilage through the use of stem cells. Another is studying the biomechanics of joints -- how they function, particularly the knee and ankle.
And in the lab known as the Coach K lab, we're studying problems such as stress fractures in the lower extremities, and how athletes and others can reduce injury and improve performance. All labs have a clinical focus, but come at it from different angles. All our research is focused on better patient care.
For more information or to schedule an appointment, call 888-ASK-DUKE (888-275-3853).


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Scott Cleaver - 10 April, 2013
My 5 i'm listening to...
1)Stereophonics "Graffiti on the Train"...much more mature sounding but still as full on and rocky, would love Bono and Kelly Jones to Duet...or U2 and stereo's to combine as they did with Green Day,
2)David Bowie "The Next Day"...awesome!!!
3)Amok - "Atoms for Peace"...just damn clever :)
4)Mumford and Sons - "Babel"...perfectly them, and down with such style...love it :)
5)Depeche Mode - "Delta Machine" Just classic...and a nice re-birth for them :)
siggitomm - 10 April, 2013
some good shit
The Avett Brothers, Mumford and Sons, Ray Lamontagne, Bon Iver and of course U2.
cidamary - 10 April, 2013
About the best show of the tour 360°...
Precisely 2 years ago, we were at the Morumbi stadium - Sao Paulo, Brazil celebrating the historic achievement of 360º Tour being considered the most lucrative in the history of music ... If anyone wants to check how it happened I've found some links:
An interview for a local TV: http://www.youtube.com/watch?v=xg2g3newK0E&feature=youtu.be
PS: I have no commercial interests only wanted to share those magical moments in Sao Paulo. Kisses for you all from U2 and for all the fans like me.
norwaylad - 10 April, 2013
Jake, Van , Bob , Christy and Meshell.
Jake Bugg Jake Bugg, Van Morrison No Plan B,Meshell Ndegeocello a dedication to Nina Simone,Bob Dylan Tempest and Christy Moore Listen.
abraham1 - 10 April, 2013
Rob Rock, Stryper, Chickenfood, The Cult
U2 always at the top, Rob rocks, Stryper with blackened, Chickefoot pretty tight, The Cult amazing with "for the animals" and Golden resurrection pretty amazing symphonic metal. These days I have been watching concerts in youtube of Joshua Era, pretty good concert
hzham - 10 April, 2013
05 Albums
The Killers "Battleborn" , Depeche Mode "Delta Machine", Iron Maiden "Maiden England", U2 "War" +
Simple Minds "5x5 Live"
PaDDY JOE - 10 April, 2013
Hi 5
Simple minds, Big country,Peter Gabriel,The Alarm and The Sundays.
The_Dissident - 09 April, 2013
Noise?, Sound?, Music To My Ears
1: Reign Wolf aka Jordan Cook, That guy can take a guitar and set it on fire 2:Gavin James, Kodaline & John Smith Three artists I'm clubbing together because of their links to Ireland...cheating I know but worth a listen, 3: Archive.. One of the best kept secrets of British bands, Phenomenal sound and always reinventing themselves, Do not let them pas you by 4: Brother Dege.... the way the blues should be played and finally 5: Dry The River...check out their song 'No Rest' then do yourself a favour and explore their album, There's a lot of good music out there just now if you look hard enough, Glad to see Adam name checking 'The Villagers' I could go on.... Gin Wigmore...The Silent Comedy.....Clutch...Of Monsters & Men....The Lost Brothers..Steven Wilson
electricco - 09 April, 2013
very 70s 80s
My Top 5 1) U2 2) neil young 3) roger Hodgson 4) PJ 5) Muse
Nikaliptus - 09 April, 2013
The Original Rudeboys
Not going to come up with five bands/albums right now, but I was lucky enough to catch The Original Rudeboys when they supported The Script in Melbourne & Sydney this past weekend, and I can't get enough of them right now, so take my (and Adam's) word for it, and check out their album 'This Life'.
lefpiresbb - 09 April, 2013
my top five
here is what i have been llistening : 1) neil young; 2) morrissey; 3)ramones; 4) paul mccartney; 5) pink floyd.
ps. i´m always listening to U2.
kevfly82 - 08 April, 2013
My 5 album & live picks
My 5 live picks I'm into this year: 5) Mumford & Sons - what energy for such a stripped down band. 4) Metallica - just watched Quebec Magnetic live DVD- kickin ass & taking names. 3) Rolling Stones- 50 years of the best rock n roll means something. 2) Pearl Jam- playing Wrigley Field in Chicago this year, special show. I've got my ticket! 1) Tom Petty & the Heartbreakers- doing 5-night residency at Beacon Theatre in NY in May, playing lots of deep & rare cuts...U2 should take notice. I'm going for 2 of the 5 nights....Now My 5 album picks I'm into this year: 5) The Divine Fits - some cool grooves. 4) 'Babel' - Mumford & Sons. 3) 'Mojo'' Tom Petty & the Heartbreakers. 2) 'Circuital' - My Morning Jacket. 1) U22 & U2360 Edge's Picks- some of the bands best cuts...Zooropa & Even Better are tight. -Kevin/ Chicago
diegoqvu2 - 08 April, 2013
The Cure
During these days i've been listening a lot of The Cure (because they will come to my country :D), and Depeche Mode's last album
LetMeInTheSound7 - 08 April, 2013
Yoshino Blossom and Boomerang1/2
I've been listening to the instrumentals from Unforgettable Fire and they're stunning! Sound really great, as for band wise which is always U2 i'd also say:RUSH,Simple Minds,The Killers, and Foster the people.
pdunlap - 08 April, 2013
We Are Augustines
Frightened Rabbit
Amanda Palmer
Los Campesinos!
Neko Case
buzz2 - 08 April, 2013
My five NEW acts that are worth your tim
Wild Belle- their album "Isles" is awesome.
Palma Violets-180 Great noise from England.
Haim- Great band can't wait for their album whenever it comes out.
Diamond Rings-love 80's techno? Check it.
Gold Fields-this is what it sounds like if Duran Duran and INXS had a baby.
rodrigoms2000 - 08 April, 2013
new album
adam said the band wants a new record out by september, october or november. I can't wait any longer!!!!
cristiu2 - 08 April, 2013
Even better than the real thing? Coming
My favourite bands at the moment are:
1. The Boxer Rebellion (should be U2's next support act! (album out may 13th)
2. The Joy Formidable (Great band from Wales, U2's second support act!) (Just released Wolfs Law)
3.Kashmir (From Denmark, moving new album EAR)
4. Editors (new album coming soon)
5. Mew (From Denmark, new album coming soon)
NanyandGonzo - 08 April, 2013
Right now?
Well, right now, I have going back to two of my idols obviously: The Unforgettable Fire, Side B, I keep going back to The Three Sunrises and Disappearing Act a lot, as well as "Medium, Rare and Remastered," I've been listening to those beautiful songs, I wish some of them were played live once. My third album is from Robert Downey Jr, "The Futurist," it has been my soundtrack to my reading the book "Gabriel's Rapture" by Sylvain Reynard, Downey is amazing and I wish he had done others too, he's voice is awesome and the lyricis are so powerful. The 4th is by Richie Sambora, "Aftermath of the Lowdown" his song Every Road is amazing, I like the lyrics and the rhythm. Finally, from Bon Jovi, "Lost Highway" have some significant ones, they're always very uplifting and they indeed can cheer anyone up.
Cláudio CS - 08 April, 2013
Deftones, Alice In Chains, Depeche Mode,
I have been actually listening too much to the last Depeche Mode´ "Delta Machine", Deftones´ "Koi No Yokan", Soundgarden´ "King Animal", and hardly can wait for Alice In Chains´ "The Devil Put Dinosaurs Here", and Rob Zombie´ "Venomous Rat Regeneration Vendor".


text: 5 Apps for Job-Seekers Looking for work is a drag, but these days your phone can help you network, find openings, and nail the interview. By Christina DesMarais Email Comments 0 Share Back 3 of 5 Next Return to Gallery Return to Gallery Back Next View Thumbnails 101 HR Interview Questions and Answers For: Android Price: Free You've landed the interview. Now don't screw it up. This app asks common interview questionslike the dreadful "What is your greatest weakness?"then lets you tap to answer and gives you advice on how to handle the question during the interview. Return to Gallery Return to Gallery Return to Gallery Back 3 of 5 Next Return to Gallery Back Next Return to Slideshow Related Links


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I got the same issue here, and i wonder if there is already a solution for this problem. (because the thread is from 2009). I'm using inventor 2013.
i also get into the same issue
is there something done meanwhile?
You could set Tools>Application Options>General tab to a real small value on Annotation Scale to make them less visible, but this will also make sketch dimension annotations very small.
Thank you for the input but that´s not what i´m searching for
michael.marx wrote:i also get into the same issue
is there something done meanwhile?
I just found that by going to properties for the sketch into which you've imported the ACAD drawing, you can change lineweight and all the points become far less prominent.
Log into access your profile, ask and answer questions, share ideas and more. Haven't signed up yet? Register
Start with some of our most frequented solutions to get help installing your software.


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Serious Eats - seriouseats.com
Quick Bites »
News in one quick bite.
WTF: Chris Bianco to Costar on 'Bizarre Foods'????
Chris Bianco, my good friend and soon to be co-star on Bizarre Foods of Arizona coming your way in April/May, is also taking a leave...but the pizzeria is still open.
W. T. F.? [via Landry]


text:
Sports Bra Tops
Mak Attack Fitness Wear includes a high-end quality of womens sportwear, tank tops, sports bras, and specialty fitness clothing. It is made with a high-thread count Supplex fabric. The supplex fabric sports top and long tank tops fit the body in the most flattering ways. The collection has a variety of bright and energizing colors, as well as several styles of solid supportive athletic tops and brazilian sports bras.


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Search for brakes by vehicle:
Brake components should be installed by a competent mechanic in a professional manner. Any incorrect installation of brake components can cause a major safety problem or an accident. If you are not a competent and qualified mechanic you should not attempt to install these products, but should take the vehicle to a vehicle dealer or competent automotive mechanic for their installation.
Disc brake pads and rotors are wear items and as such, should be inspected regularly and replaced as necessary. Read More.
Lea en español
Read this page in English
For over 15 years, Hawk Performance has dominated the racetrack by providing champions with cutting-edge friction materials. Whether you are looking to improve your braking ability during the next lapping day or looking to make your move on the final lap, Hawk has you covered with a wide array of Motorsport Compound Pads.
SPECIAL NOTE: Due to the aggressive nature of the Hawk Performance Motorsports Compound pads, they are not recommended for street use.
HT 14 Compound
Temp Range: 300-1,400 degrees FahrenheitTorque: Very HighRecommended Use: Designed for vehicles that achieve high top speeds and require repeated high deceleration rates during road race competition. Sports Car/GT and higher horsepower, open wheel applications.
Por m�s de 15 a�os Hawk Performance ha dominado las pistas de competencia suministrando a los campeones los materiales de fricci�n m�s avanzados del mercado. Hawk ofrece una variada l�nea de materiales de fricci�n para veh�culos de competencia, ya sea para mejorar su frenado en general o al pasar al primer lugar en la �ltima vuelta.
NOTA: Debido a la agresividad natural del material de fricci�n utilizado en las pastillas Hawk Performance Motorsport, no se recomienda que sean utilizadas en las carreteras.
Compuesto HT 14
Rango de Temperatura: 300-1,400 grados Fahrenheit ( 149 - 760 grados cent�grados)Torsi�n: Muy Alta.Uso Recomendado: dise�ado para autos con altas velocidades m�ximas que requieren repetitivos y altos �ndices de desaceleraciones en carreras. Autos deportivos/GT y con m�s caballos de fuerza, al igual que F�rmulas.
Most Recent Reviews Read all reviews | Write a review
2008 Ford Shelby GT500Coupe
Vehicle Miles: 12,000
Location: alto, Mi
Driving Style: Spirited
Miles ofproduct use: 3,000
Pads: Hawk HT-14 Track Only Pads
Lines: Stock
Calipers: Stock
Rotors: Power Slot Power Slot Rotor
0 of 0 people found the following review helpful:
September 23, 2011
These are matched with HT-10 on the rear. They wear like Iron and the stopping power/torqe is very linear. This is a heavy car I run on NASA Track Events. The HPS & HP+ don t do the job as well on a heavy - high horse car. They are noisy, but I have no problems driving them on the street. Even cold the 14" brakes have all the stopping power needed on street duty if you are as lazy as I am and don t want to change them. I drive about 2500 mi on track and 500 miles on the street each year.
Product quality, excellent consumer info, world class service and price. That's Tire Rack. Read More
Home > Brakes > Pads/Shoes > Hawk HT-14 Track Only Pads


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These Speed & Strength Resistance Chutes increase running speed with enhanced explosiveness. It has 2" Wide "Cushioned" and "Adjustable" waist belt (24" to 40" waist) with fast release velcro closure and adjustable length Tow Strap (30" to 60") with fast latch to waist belt.
Similar Items by Category: Football > Training Equipment > Player Speed Training
Product Description
Chute is fluorescent orange
Key Features:
* Increase running speed with enhanced explosiveness
* 2" Wide "Cushioned" and "Adjustable" waist belt (24" to 40" waist) with fast release velcro closure
* Adjustable length Tow Strap (30" to 60") with fast latch to waist belt
* 39" Square Chute made of rip-stop nylon, with 8-shroud lines to minimize tangles
The speed chute is perfect for adding resistance to your running drills. Use it to increase running speed, explosiveness, acceleration, and lower body strength. The speed chute has a quick release velcro belt, which is great for over-speed training. The waist belt is adjustable up to 40 inches. Item includes speed chute & belt.
Chute made of good quality Nylon fabric without panels for economical price range, complete with cushioned belt.
Used to build sprint speed, the Speed Chute combines resistance with over-speed running, the two key elements of speed chute training. During the initial part of the run Speed chute provides resistance for strength training, then release the Speed Parachute (via fast release belt) to initiate the over-speed phase. Feel the "Burst of Speed!" This combination increases your strength, stamina, speed, explosiveness and acceleration while it improves your running technique.
At the point of release (via fast release belt) the athlete will Feel the "Burst of Speed," immediately followed by a period of lengthened stride and speed similar to downhill running. With practice, your body will be able to achieve these bursts unassisted.
Due to color differences in monitors, the colors on this site are for reference only. Please contact Epic Sports if you have any color questions.
Frequently Bought With
Best Seller Ranking
- #4 in Football > Training Equipment > Player Speed Training
- #58 in Football > Coaching Equipment
Customer Reviews
M. DEBERARDINO (North Carolina) on February 12, 2014
Excellent product.
C. QUINTANILLA (Texas) on September 11, 2012
Well made & worth the investment.
T. WHITE (Georgia) on March 12, 2012
This is a great Chutes my husband coach the 6 and under boys and they love using it in practice. Some times they don't even want to play football they just want to run with the chute. I just recently ordered another one b/c I wasn't sure if it was going to fit our boys but it did!!!!!
A. TAVARES (California) on October 2, 2010
D. RAY (Virginia) on September 28, 2010
Great price and product!


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VANS Authentic - All Lined Up
The video noise-style stripe pattern featured on Vans' exclusive All Lined Up Authentics goes back to some of the trippy skate and surf styles of the 1980's. That retro look could only work best on these, the world's first-ever skate shoes.
- Classic canvas upper.
- Five eyelet lace-up.
- Padded collar and footbed for long-lasting comfort.
- Vulcanized rubber midsole with super flexibility.
- Original gum rubber waffle pattern sole provides maximum traction.


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Topics in this article:Detroit City Council Emergency Manager
Originally Published: June 26, 2013 9:48 AM Modified: June 26, 2013 3:38 PM
Gary Brown steps down from Detroit City CouncilBy Associated Press
Gary Brown
Related links
Detroit City Council President Pro Tem Gary Brown has announced plans to resign his post and take a job working for the city's state-appointed emergency manager. Brown said in a statement Wednesday he'll step down effective July 1. He says the job working for emergency manager Kevyn Orr will focus on "pivotal areas ... where Detroiters will feel the greatest positive impact." Orr says Brown will become Detroit's chief compliance officer, spearheading efforts to right-size and reform city operations as part of a broader restructuring. Brown will earn $225,000 a year. Brown was elected to Council in 2009. With Brown stepping down, only seven council members will remain. Kwame Kenyatta resigned last week. The Council lost much of its authority when Orr was hired in March to fix Detroit's finances. Topics in this article:Detroit City Council Emergency Manager
Related Content:
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Runners in Saturday's Run or Dye, a 5K color run at the Lancaster Event Center in Lincoln, were showered in eco-friendly, plant-based cornstarch dye at every kilometer mark during the race. Afterward, they were invited to join in a Dye Festival to Tie-Dye the Sky as well as each other. The race is dubbed a celebration of life, friendship, fitness and fun.
Click here for a slideshow of the Run or Dye 5K.


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On-Campus Reserved RV Parking
Welcome to the University of Alabama Gameday RV information page! Here at the University of Alabama we are very proud of our RV following and tradition.
All on-campus RV parking passes are non-transferable.
An RV pass is required to enter all RV lots located on the University of Alabama campus. RV's are only allowed to park in designated RV lots on the University of Alabama campus.
Arrival Time
The entry time for all on-campus RV lots is 6:00 p.m. on Friday before a home game.
RV Parking Available Off-Campus
All on-campus RV parking is sold out for the football season.
Click Here to view several off campus RV lots
RV Info Links
Click here to view the Gameday RV Parking Map
Click here to see the rules and regulations for UA Campus RV Lots
Click here for more information on the Crimson Ride Transit System
The following lots on campus are controlled by the University of Alabama Gameday staff. RV's parked on campus will only be allowed to park in designated RV lots. Please note that all lots on campus open at 6:00 p.m. on Friday before Gameday.
Click on a lot below to see the layout.
UA Pet Policy
Pets are permitted at the University of Alabama RV Lots. Pets must be crated, caged or upon a leash not longer than 6 feet or otherwise under physical restrictive control at all times. Pet owners are required to pick up after their pets and properly dispose of their droppings. Pets should not be left unattended.
Northington Lot
The University offers both RV staging and a FREE RV lot at the old Northington Campus behind Belle Food's Supermarket on McFarland Blvd. This lot will not require reservations for non-SEC games and will be FREE to the public. It will not be monitored and has no hook-ups available. The lot will be open Thursday at 8 a.m. until 12:00 p.m. Sunday for each home game weekend. Fans may choose to stay in this lot Thursday night before arriving on campus on Friday afternoon, or they may stay all weekend.
We expect huge crowds of visiting fans with RVs for SEC games. We want to make sure that UA fans who plan to bring an RV to town for those games get a reservation. As of right now, the Northington Lot is completely reserved for all SEC games in Tuscaloosa. We request that anyone with a reservation cancel by Wednesday at 5pm before the game to allow us to use your space. You must also arrive by 6 p.m. the evening before the game to ensure your space is not given away.
Click Here to see the Northington Lot layout
Everyone is required to have an exhaust stack that extends above the RV, if you plan to run a generator. Those individuals without proper stacks will be required to turn off their generator.
To access this area as you are heading west on Hwy 82 W (McFarland Blvd), turn right just before the Fire College Training Center and Bruno's Supermarket, directly across from Chick-fil-A.
Please observe the open and close times for the Northington RV lot. RVs or vehicles left after lot closing time will be towed at the owner's expense ($250-$300).


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Top pick CANON REBEL G 35MM FILM SLR CAMERA BODY 500N MISSING GRIPThis item appears here because it is the lowest priced, Buy It Now item from a highly rated seller. | Used Returns not accepted Oroville, WA, USA | |
$9.95Price |
Free shipping
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Buy it nowProduct Identifiers | |
Brand | Canon |
Model | EOS Rebel G / 500N Body Only |
MPN | ACC54798, eos500 |
Key Features | |
Camera Type | SLR |
Film Type | 35mm |
Lens Mount | Canon EF |
Battery Type | 2 x 3V Lithium Battery (CR-2) |
Focus | |
Number of Focusing Points | 3 |
Shutter | |
Shutter Speed | 30 to 1/2000 sec |
Maximum Flash Sync Speed | 1/90 sec |
Exposure | |
ISO Range - Automatic Setting | ISO 25 - 5000 |
ISO Range - Manual Setting | ISO 6 - 6400 |
Frames per Second | 1 fps |
Manual Shooting Modes | Aperture Priority, Fully Manual, Program Shift, Shutter Priority |
Light Metering Modes | Center Weighted, Partial Metering, TTL |
Flash | |
Flash Recycling Time | 2 sec |
Red Eye Reduction | With Red Eye Reduction |
Flash Guide Number | 39 |
Film Transport | |
Film Auto Transport | Loading, Prewind, Rewind, Transport |
Viewfinder | |
Eye Relief | 18.5 mm |
Viewfinder Frame Coverage | 90% |
Viewfinder Magnification | 0.7X |
Dimensions | |
Depth | 2.44 in. |
Height | 3.63 in. |
Width | 5.63 in. |
Weight | 12.32 Oz |
Miscellaneous | |
Color | Black |
Automatic Shooting Mode | Fully Auto, Landscape, Macro, Night, Portrait, Sports |
Additional Features | Auto Exposure, Interchangeable Lenses, Panorama |
Release Date | September, 1996 |
Average review score based on 125 user reviews
of customers recommend this product
The Canon EOS Rebel G is a run of the mill, no frills, film camera. They are price around the $20 - $25 range for body only. That's for a one in very nice condition.
If you are a Canon DSLR user, decided to take some photography classes at the local college and realized that the class was about shooting film, this is the camera for you. Same goes for any beginner photography student. You are way better buying a Rebel G or similar for under $30 then digging out that old SLR camera from your dad's closet and trying to get that to work.
It uses the standard EOS EF mount. ...but the lens mount is plastic. Not a huge deal, but if you plan on using the camera with heavy lens, might not be a long term solution. Is has the standard exposure modes, AV, TV, P, M and Auto. Frames per second isn't fast, no spot meter, the viewfinder is small. Like I said eariler, if you need it for some photography classes, it's great. I you are looking to expand your horizons and shoot film along with your digital, I would strongly recommend looking a little higher up on the Canon scale. For not that much more, you can find the Canon EOS A2,A2E,5(Europe Name). It's a semi pro camera, with some really nice features... Metal lens mount, faster frames per second, better over all camera. ...and with the A2E or EOS 5, you get eye control focus. Back in the day, I went from a Rebel to a EOS 5 and loved the move. The A2E/5 models are little bigger and a little more heavy, but not buy much. ...not as heavy as the EOS 1 series. So, in that sense, you can stash it in your photo bag and not notice the extra weight.
So, in summary, the Rebel G is a entry level camera. Anything more than a temporary camera for school, look higher up on the Canon lineup.
Great camera, does quite a lot. Its very light which is a pro when you mount your 50mm, but a con when you mount the 70-200 2.8 (where it feels very off balance). The shutter button is pretty stiff with this camera, but you can get used to it.
you get four "custom settings", beep on/off. bracketing, # of photos per "burst", and another i can't remember. Three autofocus points, and you can switch between the three, but i usually leave it on the middle one. The AF points are hard/impossible to see in low light so its tough to make sure you're getting a precise focus on exactly what you want.
The af assist beam is actually brighter than the one on my digital rebel t2i!
stops are in 1/2 stop increments. If you develop your own film this is fine, if you send it off, you may want 1/3 stop increments.
All for $20 on ebay. pretty good deal.
The EOS Rebel G is fully automatic, ultra compact, quiet and comes equipped with a built-in retractable flash. It features a high-speed selectable 3-point autofocus system with A1 Focus for improved performance, and Canon's exclusive AIM (Advanced Integrated Multi-Point) control system which links Rebel G's three-point autofocus to multi-zone metering for available light and flash. Offering 11 exposure modes (Full Auto to metered manual with indicator) plus Multiple Exposure, Exposure Compensation and Auto Exposure Bracketing, it has an enhanced Command Dial for operating mode selection, and is fully compatible with Canon's complete line of EF autofocus lenses and EOS System Specialties, including Battery Pack BP-8, Grip Tripod GR-80TP and Remote Switch RS-60E3. New features like Auto Exposure Bracketing (in 1/2 stop increments up to ? 2 stops) and E-TTL Autoflash (enables high-speed synch for automatic fill flash), and improvements like better control of Red-Eye Reduction, the In-Focus Beeper and the Auto Exposure (AE) Lock make the EOS Rebel G the most advanced Rebel yet.
I have the Canon 300D - UK equivalent to the Rebel. I have found this camera easy to use, and as much as people try to teach me about photography, the best way to learn is to experiment with what you have. The "Auto" setting is great and I have fun changing apertures and shutter speeds etc; it's not like the old days when you had to pay for every print ........... you can just delete anything that you don't like. It's compact, light and fits nicely into my hands. I have just invested in a macro lens and can't wait to get started with that. I also feel that with this camera, like most others, you should invest in a good tripod ... just put it on my Christmas wish list!
The Rebel G isa GREAT little camera! It's lightweight, yet packs an impressive amount of features. And, since these have been 'updated' by newer cameras in the Rebel series, they're available at (what I believe is) a bargain price!
I did a fair amount of research, and the newer models are only slightly faster. As for picture quality I think the G is just as good. And in 'full auto' mode, it's basically foolproof!
This is a great camera, easy to use, yet packed with enough features for more 'advanced', or creative photography. I like how all of the Canon Rebel series are easily changed between Auto, Aperture Priority, & Shutter Priority modes. All in all, a versatile, easy to use... and inexpensive!... camera that takes BEAUTIFUL photos!


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IIE provides research and program evaluation services to domestic and international governmental agencies, non-governmental organizations, and foundations to facilitate the collection of more comprehensive and policy-relevant data on international education, and to assess the impact of international fellowship and scholarship programs.
IIE's Center for Academic Mobility Research (CAMR) has extensive experience in carrying out all stages of a program evaluation, from program process and implementation, to examining outcomes and program impact. Our evaluation work has focused on assessing the effectiveness of international fellowship and scholarship programs that benefit undergraduate students, graduate (post-graduate) students, faculty, and mid-career professionals, including many programs that seek to develop leadership skills or promote access to higher education among underserved populations. This unique combination of substantive knowledge of the international exchange and leadership development fields and our methodological expertise equips us well to study the impact and multiplier effects of a wide range of programs.
Launched in July 2013, this groundbreaking ten-year study will examine the personal and professional impacts of IFP on over 4,300 fellows from marginalized communities in 22 countries.
Learn more about the IFP Alumni Tracking Study
Begun in spring 2013, our comprehensive monitoring and evaluation framework assesses changes in scholars' knowledge, skills, and attitudes, as well as an integrated analysis of the global network being created by the Cargill Global Scholars as they continue their academic and professional lives.
Learn more about the Cargill Global Scholars Program
A three-year evaluation that captures the impact of the Alcoa Foundation's support to advance research in the sustainability field being carried out at universities, NGOs and research institutions in 5 continents. Our focus is on collecting qualitative data about the applicability of the research work at the scientific, community and corporate levels.
Learn more about the Alcoa Sustainability Research Initiative
A two-year evaluation of IIE's Scholar Rescue Fund (SRF) Iraq Project analyzes impact of the program on its grantees, on Iraq's higher education and scientific research sectors, on the host countries' academic communities, and, more broadly, on the field of emergency response for scholars.
Learn more about the Iraq Scholar Rescue Project
This longitudinal study will measure changes over two years to understand the potential effects of the HER pilot program in Ethiopia. A quasi-experimental design measures key program effects among a group of young women in secondary school and their counterparts who were not chosen for the program.
Learn more about the HER Program
Our approach to assessing the efficacy of fellowship and capacity-building programs draws on IIE's deep understanding of the various program elements needed to bring about change at the individual, community, and societal level. We recognize that it takes many years to achieve measurable impact and to bring about social change. Therefore, at the outset of the project, we work closely with program staff to develop a comprehensive and clear logic model or theory-of-change that maps out the short-, intermediate- and long-term outcomes that are expected from the program and the pathways and logical links through which these changes are likely to occur.
Most of IIE's evaluations have required a mixed-methods approach that combines qualitative and quantitative data and analysis, but we also have the capability to design and conduct rigorous evaluations that use a random assignment approach. For programs with a large number of participants, IIE also uses social media to stay in touch with thousands of program alumni and potential respondents dispersed all over the world. This networking is coordinated through popular sites such as Facebook and Twitter, and through our recently revamped IIE Home Page. We harness these, as well as other tools, for alumni tracking, for sustaining alumni networks, and for conducting quick snapshot surveys that complement the in-depth data collected through the techniques described above.
Learn more about our Center's evaluation capabilities (577 KB, PDF)
Please contact us at email@example.com for more information about our evaluation services.
IIE's research reports and policy papers serve as a rapid response to the changing landscape of international education.


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Growing up, I always wanted to host a Christmas dinner: guests seated around a beautifully set table, the smell of homemade biscuits in the air, amber lights glowing on a fresh-cut tree. So this year at my farm in Indiana—the haven where I go to replenish myself after days of constant doing—Stedman and I brought together nine folks for a celebration complete with the two ingredients guaranteed to make any gathering big fun: great laughs and good food.
Days before the first guest steps through the holly-decorated doorway, my chef, Art Smith, begins dicing, chopping, mincing, and brewing to stir up a menu with some of my all-time favorite fixin's: slow-roasted chicken with wild rice dressing (the perfect "I'm sick of turkey" choice), pantry tomato tart (a dish I've always loved), and sautéed greens with shallots (a scrumptious way to get those veggies in). Art always knows to start the meal with soup. As a child, I would watch Lassie, and there was always a Campbell's soup commercial where Timmy's mom would feed him soup that was "M'm! M'm! Good!" Ever since, soup has been my favorite thing to have for lunch, and in winter I have it almost every day. For this special dinner, I ask Art to mix up the soup I most often request: spicy winter squash. He makes his with butternut squash (it's absolutely de-lish!), but he tells me that any kind of winter squash will do: calabaza, hubbard, or, in a pinch, even a sugar pumpkin. Few people get more excited about a party than my best friend, Gayle King. "I've just seen Art's menu," she exclaims hours before our dinner. "I can't wait." One by one, soon after dusk, the eight other guests arrive: Stedman's daughter, Wendy Graham; my father, Vernon Winfrey, and his wife, Barbara; my godmother, Rosalind Eddins (I call her Mrs. E), and her husband, Calvin; my longtime pals Mary Kay Clinton and her husband, Tom O'Brien. And of course, there's my one very special guest who steps in, working her new do: my goddaughter, 8-year-old Katy Rose, child of Mary Kay and Tom—whose flip is fabulous. From the December 2002 issue of O, The Oprah Magazine
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Four days after Malaysia Airlines Flight 370 took off from Kuala Lumpur, crews have found nothing.
A 10-year-old was injured in Brown County after a being hit by a vehicle while riding on a John Deer Gator.
Authorities say a 10-year-old boy was riding on a the utility vehicle with his aunt when a vehicle struck the Gator from behind. It happened around 4:15 p.m. on Hamer Road in Washington Township.
Dispatchers say the boy was conscious and talking after the crash.
Aircare was called to the scene and the child was taken to a nearby hospital.
We will continue to update this story as more information becomes available.
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Griffith Nabs KIAC Player of the Week Honors
Asbury University junior Lakin Griffith was named the KIAC women's basketball player of the week by KIAC officials on Monday, December 12th.
Asbury started the week with an 83-82 overtime loss to Taylor University, but rebounded with a pair of wins to close the week. The Eagles defeated Central Christian (Mo.) 86-58 and Ohio Christian University 89-82. Griffith averaged a double-double last week with 17.7 points and 12.3 rebounds per contest. She scored 25 points and grabbed 20 rebounds against Taylor University, marking only the second 20-20 game in school history. She recorded another double-double game with 18 points and 12 rebounds against Ohio Christian. The junior forward shot 53.8 percent from the field (21-of-39).
Asbury University has an overall record of 7-8. They will return to action in an exhibition game at Utah State University on January 3rd.


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COLUMBIA — The (U)Matter Club members took to the streets of Columbia, wiping out as much graffiti as they could Saturday. The task was part of Youth Service Day.
SLIDESHOW: (U)Matter tackles graffiti for Youth Service Day
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Wednesday, July 11, 2012
Strawberry Shortcake (See Jane Make)
I bought a huge carton of strawberries on Sunday (on sale, hence the huge container) and subsequently panicked. Strawberries turn quickly and I knew that if I didn't use them soon, they'd go to waste. As soon as a entered "strawberry" into Google, the genius that is autofill took over and the rest is history.
Cut up strawberries and let them marinate in their own juices by adding some sugar and lightly smashing them. I made a simple shortcake out of this recipe and also homemade whipped cream (I used 8 ounces of heavy whipping cream, added a teaspoon or so of sugar and whipped until I had soft peaks).
18 comments
- Andrea said...
Looks delicious!! What a great idea for a summer desert!! :)
xo Andrea
Wonderful and Marvelous - July 11, 2012 at 2:03 AM
- Sarah said...
That looks absolutely divine. I love strawberry shortcake!
Keep calm and carry lipstick. - July 11, 2012 at 3:10 AM
- Soulofashopper said...
Looks delicious!!! now I´m hungry! :) xo, Alma
http://www.soulofashopper.com - July 11, 2012 at 3:59 AM
- seaandswank.com said...
- July 11, 2012 at 6:46 AM
- Cara said...
my fave!
- July 11, 2012 at 7:07 AM
- Taylor said...
YUMMMM!!! I am going to have to make this even if I eat it all alone! The Hubs isn't a strawberry fan - so every summer I feel like I miss out on this! YUMM!
- July 11, 2012 at 7:15 AM
- pretty little things said...
that strawberry shortcake looks sooooo delicious! xo
http://allthingsprettyandlittle.blogspot.com/ - July 11, 2012 at 7:41 AM
- ahhhline said...
yummy! i'll have to try the recipe.
avenueahline.blogspot.com - July 11, 2012 at 9:04 AM
- Jackie said...
This looks so delicious! I don't think I've ever had strawberry shortcake but I might just have to make this!
http://daydreamer-alifestyleblog.blogspot.com - July 11, 2012 at 9:57 AM
- LV said...
I love when you post recipes! Strawberry shortcake is one of the best desserts to have in summer. This looks yummy!
- July 11, 2012 at 10:12 AM
- Collections said...
omg wow. This looks incredible.
Collections - July 11, 2012 at 11:07 AM
- annacbie said...
holy delish!
http://www.annacbie.com - July 11, 2012 at 3:21 PM
- Amy said...
Looks fabulous!
Leopard and Lillies - July 11, 2012 at 9:25 PM
- Josie said...
It's so gorgeous! I love strawberry shortcake and this one is super pretty and simple.
xo Josie
www.winksmilestyle.com - July 11, 2012 at 10:16 PM
- Meagan Murtagh said...
xo the egg out west. - July 11, 2012 at 10:39 PM
- octoberchic.com said...
Delicious!! I love strawberry shortcake.
octoberchic.com - July 11, 2012 at 11:48 PM
- Grace Lynne Fleming said...
holy moly that looks delicious
http://herumbrella.com - July 12, 2012 at 12:02 AM
- Sal said...
Im thinking this is a must do before the summer ends!! xo Thank you for sharing!
www.bluebonnetsforsal.com - July 15, 2012 at 12:17 PM


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Black Tea Assam Assam, Khongea Estate Darjeeling, First Flush Darjeeling, Second Flush Dian Hong - Golden Needle Golden Monkey Irish Breakfast Keemun Keemun - High Mountain Northwest Tea Time
Chai Masala Chai - Roast Chai - Sweet
Green Tea Dragonwell Gunpowder - Pinhead Mao Feng Sencha
Herbal Tisane Chamomile Copper Lemon Damiana Emerald Mist Floral Sonnets Hibiscus Honeybush Licorice Root Rooibos
Oolong Tea Bai Hao Golden Lily Phoenix Oolong Ti Kuan Yin - Baked Ti Kuan Yin - Green
Pu-erh Tea Pu-erh - Loose Leaf Pu-erh - Tuocha
Scented Tea Earl Grey Genmaicha Jasmine Pearl Lapsang Souchong Moroccan Mint Yin Hao Jasmine
White Tea White Peony
This fine example of Assam is grown on the Khongea Estate in the lowlands of Assam, India. The heavy rains of the monsoon season in this region are what give Assam tea its classic "malty" characteristic. This particular tea has a unique sweetness, reminiscent of wildflower honey. Its brisk flavor and medium body make it ideal as breakfast tea, though the World Spice team takes it all day long, buoyed by milk and sugar in the British tradition. This crop is easily the best we've seen in years, sure to please longtime Assam drinkers and new converts alike. Brew for 2 to 3 minutes at 205°F; 1 steeping.


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Accused Child Molester "Pastor" Bob Grenier of Calvary Chapel Visalia falsely defends allegations..
Feb 25, 2012 | Posted by: Not Alone | Full story: calvarychapelabuse.com
Bob Grenier's defense to the Calvary Chapel Visalia Board leaked: Following is the outline / notes of BG's response to his Board in 2009 after they were confronted with the Child Abuse allegations, etc.
Since: Nov 09 130 Location hidden |
Ask yourself why CCVisalia's board of elders isn't insisting on reconciliation when it being sought by the children. If not that then why not bob's resignation.
Is there bible different then the rest of ours? |
Child molester or child abuser, I heard the abuse allegations when was he accused of molestation? |
ExAAACtly, Danny! He wasn't. It's just something his detractors like to make up and then repeat as if it were fact. Saying it doesn't make it so, and obviously something has occurred to make NotLone post. Perhaps Bob said something in this morning's sermon that got NotLone in a ruffle because NotLone prolly podcast-listens to every semen I mean sermon.
Give it up, NotLone. Somebody call Alex Grenier and let him know that his little yappy terrier got out of his yard again, please? Next time I have to pick him up, he's going to the SPCA, Alex. I'll notify you and you can pick him up there. |
Judged: 1 |
no, he admitted to disciplining a stepson hopped up on steroids. if your steroid-injecting kin was threatening to destroy your family from the inside out, what would you do? maybe Alex' son will get hopped up on steroids, then he'll know firsthand some of the difficulties that a man of God like Bob has had to face. all this other stuff is Alex piling on because his narrative is so short on supporting facts that he tries his best to hide such lack.
Judged: 3 2 Gayle has the classic dead eyes that you see on a woman who has been so beaten down that she has no fight left in her. Alex is the only one lucky enough to have a wife to help open his eyes to the Stockholm trance he was barely surviving under. Paul will forever feel the guilt of participation in the hanous act of molestation his father performed on him and his little brother. Little brother Robert will eventually be devorced from his wicked wife who will leave him once Bob is finally behind bars. Geofe, the only one half way sain, will continue to drown those memories in alcohol. Emma is the biggest loser in this whole thing. That poor little girl is surrounded by very bad people. |
No Spin also known as Edna
Judged: 1 1 Ohhhh my name is edna I was getting money for a job at a 501c3 and the spigot got turned off an now I've got sour apples in my bowl so I'll turn my teeth to the person I want to blame. So, let's see. According to Edna, she was criticizing Alex on his hatesite. Now there's a grand alliance between Edna and Alex and now she has turned her teeth to bob at topix.com . Good Lord! Attention hoarder! |
Wow who.... you are so redicilious.... just focus on the important stufff....live, laugh, love and demand justice for those that have been wronged....simple no matter what point of view
The majority of everyone on these blogs has given personally testimony in one way or another of wrong wrong doings Bob has created and there stories have been supported by non biased wittnesses ... agrue all you want but no matter what you can't defend that.
Judged: 1 DDWho. Your day is coming soon. That old mans tit is drying up. Good luck finding a job when your families molestation story hits the real news and you are a main character in the coverup. I guess you'll have to rely on hoof clippings. That will be poetic justice. Again, poor little Emma. What fat ugly examples she has. It's to bad daddy's to stupid to take over the family business. There is big money in stealing from the church. Just ask mommy. But he would need more then a 10 year olds maturity level and mommy would need bigger hair and dead eyes. Guess daddy's just gotta slap her around some more, right Grandma? Don't worry about the Silva's, they are still drinking from the Calvary cup. Theyll come back around. |
You will see Grenier's. The statuet of limitations has not run out on child molestation. 20 years from the time it last happened.
No Bob at the helm, no money in your pockets. The rats will scatter. |
Hey No Spin, reread your post....who's wicked?
good point.
I ain't DD btw. Saying something over and over again doesn't make something true.
Since: Mar 12 5 Location hidden |
Judged: 1 1 1 |
Since: Mar 12 5 Location hidden |
Judged: 1 1 1 |
Someone finally got it right; OPINIONS that is correct. We all know what is said about opinions!!
Judged: 1 |
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Somewhere between swigging bottles of Blueprint, sweating your brains out daily, and, oh yeah, attempting to catch up on last year's lingering to-dos, resolution season can leave us all feeling a little more frazzled than fresh and new.
So, we called up some life experts for some quick-hitting tips to rein in an out-of-control day, and come out feeling calm and centered (yes, even you, stress addicts). Warning: Your excuses for being harried all the time are about to fall away-and that's actually a good thing.
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Sunitinib in Treating Patients With Idiopathic Myelofibrosis
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This phase II trial is studying how well sunitinib works in treating patients with idiopathic myelofibrosis. Sunitinib may stop the growth of abnormal cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the abnormal cells.
Condition | Intervention | Phase |
Accelerated Phase Chronic Myelogenous Leukemia Acute Undifferentiated Leukemia Adult Acute Lymphoblastic Leukemia in Remission Adult Acute Myeloid Leukemia in Remission Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative Blastic Phase Chronic Myelogenous Leukemia Chronic Myelomonocytic Leukemia Chronic Phase Chronic Myelogenous Leukemia Mast Cell Leukemia Meningeal Chronic Myelogenous Leukemia Primary Myelofibrosis Progressive Hairy Cell Leukemia, Initial Treatment Prolymphocytic Leukemia Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Myeloid Leukemia Refractory Chronic Lymphocytic Leukemia Refractory Hairy Cell Leukemia Relapsing Chronic Myelogenous Leukemia Secondary Acute Myeloid Leukemia Stage I Chronic Lymphocytic Leukemia Stage II Chronic Lymphocytic Leukemia Stage III Chronic Lymphocytic Leukemia Stage IV Chronic Lymphocytic Leukemia T-cell Large Granular Lymphocyte Leukemia Untreated Adult Acute Lymphoblastic Leukemia Untreated Adult Acute Myeloid Leukemia Untreated Hairy Cell Leukemia |
Drug: sunitinib malate |
Phase 2 |
Study Type: | Interventional |
Study Design: | Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment |
Official Title: | A Phase II Study of Sunitinib Malate in Idiopathic Myelofibrosis |
- Number of Participants With Objective Clinical Response to Sunitinib Therapy [ Time Frame: After two 6-week treatment courses (12 weeks) ] [ Designated as safety issue: No ]Participant response assessed after two cycles of therapy according to categories: 1) complete response, 2) partial response, 3) clinical improvement, 4) stable disease 5) progressive disease, 6) early death from malignant disease, 7) early death from toxicity, 8) early death because of other cause, or 9) unknown (not assessable, insufficient data).
Enrollment: | 14 |
Study Start Date: | September 2006 |
Primary Completion Date: | February 2009 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: Arm I
Patients receive oral sunitinib malate once daily for 6 weeks.
Drug: sunitinib malate
Given PO
Detailed Description:
I. Assess the response rate and the duration of response in patients with idiopathic myelofibrosis treated with sunitinib malate.
I. Assess the safety of sunitinib malate in these patients.
OUTLINE: This is an open-label, multicenter study.
Patients receive oral sunitinib malate once daily for 6 weeks. Treatment repeats every 6 weeks in the absence of disease progression or unacceptable toxicity.
After completion of study treatment, patients are followed for 4 weeks.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
- At least 4 weeks since prior chemotherapy or radiotherapy (6 weeks for nitrosoureas or mitomycin C)
- At least 4 weeks since prior major surgery
- At least 7 days since prior and no concurrent CYP3A4 inhibitors, including azole antifungals (ketoconazole and itraconazole), clarithromycin, erythromycin, diltiazem, verapamil, HIV protease inhibitors (indinavir, saquinavir, ritonavir, atazanavir, nelfinavir), and delavirdine
- At least 12 days since prior and no concurrent CYP3A4 inducers, including rifampin, rifabutin, carbamazepine, phenobarbital, phenytoin, Hypericum perforatum (St. John's wort), efavirenz, and tipranavir
- No prior antiangiogenic agents (e.g., bevacizumab, sorafenib, pazopanib, AZD2171, vatalanib, VEGF Trap)
- No other concurrent investigational agents
- No other concurrent anticancer agents or therapies
- No concurrent therapeutic doses of coumarin-derivative anticoagulants (e.g., warfarin) (Warfarin =< 2 mg/day for prophylaxis of thrombosis and low molecular weight heparin allowed provided INR =< 1.5)
- No concurrent combination antiretroviral therapy for HIV-positive patients
- No concurrent agents with proarrhythmic potential (e.g., terfenadine, quinidine, procainamide, disopyramide, sotalol, probucol, bepridil, haloperidol, risperidone, indapamide, and flecainide)
Inclusion Criteria:
- Diagnosis of MF (histologically confirmed) requiring therapy, including those previously treated and relapsed or refractory (no more than one prior standard acute leukemia-type chemotherapy regimen; no limit on prior MF - directed therapies) or if newly diagnosed, with intermediate or high risk according to Lille scoring system (adverse prognostic factors are: Hb < 10 g/dl, WBC < 4 or > 30 x 10^9/L; risk group: 0 = low, 1 = intermediate, 2 = high), or with symptomatic organomegaly.
- Serum bilirubin levels </= 2x upper limit of the normal (ULN). Higher levels are acceptable if these can be attributed to active hemolysis or MF
- Serum glutamic-pyruvic transaminase (SGPT) (alanine aminotransferase [ALT]) levels </= 2x ULN. Higher levels are acceptable if these can be attributed to MF.
- Serum creatinine levels </= 2x ULN.
- Eighteen years of age or older.
- ECOG performance status 0-1 (Karnofsky </= 70%).
- Patients must have QTc < 500 msec
- Women of childbearing potential and men must agree to use adequate contraception (e.g. hormonal or barrier method of birth control; abstinence) for the duration of study participation. All women of childbearing potential must have a negative pregnancy test prior to receiving sunitinib. Should a woman become pregnant or suspect she is pregnant while participating in this study, she should inform her treating physician immediately.
- Ability to understand and the willingness to sign a written informed consent document
- Both men and women and members of all races and ethnic groups are eligible for this trial.
Exclusion Criteria:
- Patients who have had chemotherapy or radiotherapy within 4 weeks (6 weeks for nitrosoureas or mitomycin C) prior to beginning treatment or those who have not recovered from treatment-limiting adverse events (to grade 1 or better) due to agents administered more than 4 weeks earlier. At least 4 weeks must have elapsed since any major surgery prior to study enrollment. Continuous use of supportive care medications (i. e. growth factors, anagrelide, or hydroxyurea) is allowed.
- Patients may not be receiving any other investigational agents.
- Patients who have received prior treatment with any other specific antiangiogenic agent (e.g., bevacizumab, sorafenib, pazopanib, AZD2171, PTK787, VEGF Trap, etc.) targeting VEGF/VEGFR system. Other agents that may have some antiangiogenic effects are allowed). (i.e. thalidomide)
- Patients with abnormal QTc prolongation (defined as a QTc interval equal to or greater than 500 msec) or patients who have a history of serious ventricular arrhythmia (VT or VF>/= 3 beats in a row or other significant (as judged by treating physician) ECG abnormalities.Patients with consistently poorly controlled (during the month prior to study screening) hypertension (systolic blood pressure of 140 mmHg or higher or diastolic blood pressure of 90 mmHg or higher) despite appropriate medical management of the hypertension.
- Patients who require use of therapeutic doses of coumarin-derivative anticoagulants such as warfarin. Exceptions include: patients using warfarin of up to 2 mg daily for prophylaxis of thrombosis, and patients using low molecular weight heparin provided the patient's INR is </= 1.5.
- Patients with any condition (e.g., gastrointestinal tract disease resulting in an inability to take oral medication or a requirement for IV alimentation, prior surgical procedures affecting absorption, or active peptic ulcer disease) that impairs their ability to swallow and retain sunitinib tablets.
- Patients with any of the following conditions:·Serious or non-healing wound, ulcer, or bone fracture, history of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within 28 days of treatment,·cerebrovascular accident (CVA) or transient ischemic attack, myocardial infarction, cardiac arrhythmia, stable/unstable angina, symptomatic congestive heart failure, or coronary/peripheral artery bypass graft or stenting, or pulmonary embolism within 12 months prior to study,·Class III or IV heart failure as defined by the NYHA functional classification system.
- Because sunitinib is metabolized primarily by the CYP3A4 liver enzyme, the eligibility of patients taking medications that are potent inducers or inhibitors of that enzyme will be determined following a review of their case by the Principal Investigator. Every effort should be made to switch patients taking such agents or substances to other medications.
- Patients with a pre-existing thyroid abnormality who are unable to maintain thyroid function in the normal range with medications.
- Patients with uncontrolled intercurrent illness (as judged by treating physician) including, but not limited to, ongoing or active infections requiring IV antibiotics.
- Pregnant women are excluded from this study because sunitinib is an antiangiogenic agent with the potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with sunitinib, breastfeeding should be discontinued if the mother is treated with sunitinib malate.
- HIV-positive patients on combination antiretroviral therapy are ineligible because of the potential for pharmacokinetic interactions with sunitinib. In addition, these patients are at increased risk of lethal infections when treated with marrow-suppressive therapy. Appropriate studies will be undertaken in patients receiving combination antiretroviral therapy when indicated.
No publications provided
Responsible Party: | National Cancer Institute (NCI) |
ClinicalTrials.gov Identifier: | NCT00387426 History of Changes |
Other Study ID Numbers: | NCI-2009-00207, NCI-2009-00207, CDR0000504056, 2006-0208, 2006-0208, 7700, N01CM62202 |
Study First Received: | October 12, 2006 |
Results First Received: | July 5, 2012 |
Last Updated: | October 7, 2013 |
Health Authority: | United States: Food and Drug Administration |
Additional relevant MeSH terms:
Congenital Abnormalities Primary Myelofibrosis Blast Crisis Leukemia Leukemia, Lymphocytic, Chronic, B-Cell Leukemia, Hairy Cell Leukemia, Lymphoid Precursor Cell Lymphoblastic Leukemia-Lymphoma Leukemia, Mast-Cell Leukemia, Myeloid, Acute Leukemia, Myeloid Leukemia, Myeloid, Accelerated Phase Leukemia, Myelogenous, Chronic, BCR-ABL Positive Leukemia, Myeloid, Chronic-Phase Leukemia, Myelomonocytic, Chronic |
Leukemia, Prolymphocytic Leukemia, Myelomonocytic, Acute Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative Leukemia, Large Granular Lymphocytic Myeloproliferative Disorders Bone Marrow Diseases Hematologic Diseases Neoplasms by Histologic Type Neoplasms Cell Transformation, Neoplastic Neoplastic Processes Pathologic Processes Leukemia, B-Cell Lymphoproliferative Disorders Lymphatic Diseases |
ClinicalTrials.gov processed this record on March 09, 2014