text:
Enchanted Realm
1,000,000 - 5,000,000 downloads
- Beautiful graphics
- High playability
- Smooth controls
- Not really original
Control and take care of this magic universe
Enchanted Realm is a fantasy adventure game set in a magic kingdom where you need to ascend the throne. It's a management game and that means you need to buy and build houses, renovate the older ones and gather the harvest to feed your population. As you accomplish the tasks you advance through the levels and new items become available.
The mission Book is located on the right side of the screen and you can check the tasks that you need to do there. The game is pretty self-explanatory as it's really easy to follow. There are many features and options to build and build and even you need to wait some time for the things to get done, it's equally enjoyable and addictive. It's a magic world so there are magic potions to use and the characters are adapted to the theme, as well as the buildings and the scenery.
There is no doubt that Enchanted Realm is a great game, its graphics are excellent and the controls work smoothly. Everything is impeccable and it's totally recommended. Cooper Media Corp. is the creator of Enchanter Realm and other management games which are also really popular. We hope them a long and successful career.
Visit our Facebook Community: http://www.facebook.com/apps/application.php?id=172813776141253
Game objectives:
- Develop your kingdom, which has fallen on hard times because of an evil sorceress
- Erect residential and service buildings
- Grow plants and harvest them
- Gather resources and collect taxes
- Expand your territory and increase your population
- Stock up on gold and energy
- Assemble unique collections of items
- Carry out exciting plot-driven objectives
- Earn awards and share your achievements with your Facebook friends
- Build your very own Enchanted Realm!
Game features:
- A complex storyline with many unique characters
- Highly advanced graphics and brilliant animations
- A robust simulation of city life, with all its unique peculiarities
- Over 50 unique residential and service buildings
- A tremendous selection of flowers and crops to plant and grow
- Amazing item collections
- Completely customizable territory which can be expanded for in-game money
- A spectacular soundtrack
- Special promo codes to your friends and receive rewards
- Achievements which can be shared with friends via Facebook and Twitter
Pricacy Policy: http://www.game-insight.com/legal/privacy
- Olympic theme
- Awesome quests!
- New event with impressive gifts
- New buildings!
- New collections!
- Major technical improvements!
Some lists where this application appears: Reviewed by Anna Grace, Letöltésre, Game, Analizadas por Mar GP.
Is a great app
It takes way too long for the energy to recharge. 5 min for 1 energy. Most other games only take 1 min or less for an energy. Fix this and I would like it even more. Also it shouldn't take energy to harvest the crops if it is going to take so long to rec
I love this game
It sucks
Great gamem


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Juan Manuel Fangio
Did Vettel gain respect with title?
something more than grudging respect from fellow drivers. Vettel can bask in the knowledge he has joined F1 greats Juan Manuel Fangio and Michael Schumacher as the only men to win four straight championships, but it has been far from a perfect year
Vettel weighs in on F1 dominance
finish worse than eighth. If he wraps up the title at Suzuka, Vettel will join compatriot Schumacher and Argentine Juan - Manuel Fangio as the only men to win four consecutive titles. When asked about Hamilton's comments, Vettel said there is a
Vettel looks to clinch F1 title in Japan, again
2011 feat of clinching the Formula One title in Japan with four races to spare - and join Michael Schumacher and Juan - Manuel Fangio as the only men to win four-straight championships. To clinch the title at Suzuka, the German needs to win and
BC-Car--Auto Package Digest, Car
2011 feat of clinching the Formula One title in Japan with four races to spare - and join Michael Schumacher and Juan - Manuel Fangio as the only men to win four-straight championships. By Chris Lines. SENT: 600 words. ALSO: - CAR--Auto
Vettel looks for third straight win
Alonso of Ferrari by 53 points with seven races left. The only other men to have achieved four straight titles are Juan Manuel Fangio , and Vettel's idol and German compatriot Michael Schumacher, who won five in a row. Just as Schumacher's sequence
Fangio's F1 Mercedes fetches $29.6M
Updated Jul 12, 2013 12:49 PM ET LONDON (AP) A classic Mercedes-Benz race car driven by Formula 1 legend Juan Manuel Fangio has sold for 19.6 million pounds ($29.6 million) at auction. TO THE HIGHEST BIDDER See what prompts athletes
Vettel goes from F1 fan favorite to villain - NASCAR News | FOX Sports on MSN
Schumacher's five straight from 2000-04. The only other driver to win at least three consecutive championships was Juan Manuel Fangio from 1954-57. Along the way, Vettel displayed a persona that was almost boring in racing circles. Rather than
Vettel takes points lead with GP win
Japan, is moving within sight of a third straight championship title — something only previously achieved by Juan - Manuel Fangio and Michael Schumacher. Webber claimed his first second-place finish of the season but the Australian was disappointed
A lot on the line at season-ending Brazilian GP
the 25-year-old Red Bull driver his third straight title. If that happens, Vettel will join Schumacher and Juan Manuel Fangio as the only drivers to win three championships in a row. If Vettel is fourth and Alonso wins the race at the Interlagos
Column: Ambitious Hamilton gambling with Mercedes
paid off handsomely. Five consecutive world titles in bright Italian red from 2000-2004 saw Schumacher overtake Juan Manuel Fangio as most successful driver. Hamilton was F1's youngest and first black champion when he won his only world title


text:
Systematic (IUPAC) name | |
4-[(4-aminobenzene)sulfonyl]aniline | |
Clinical data | |
Trade names | Aczone |
AHFS/Drugs.com | monograph |
MedlinePlus | a682128 |
Pregnancy cat. | B2 (AU) C (US) |
Legal status | ℞-only (U.S.), POM (UK) |
Routes | Oral |
Pharmacokinetic data | |
Bioavailability | 70 to 80% |
Protein binding | 70 to 90% |
Metabolism | Hepatic (mostly CYP2E1-mediated) |
Half-life | 20 to 30 hours |
Excretion | Renal |
Identifiers | |
CAS number | 80-08-0 |
ATC code | D10AX05 J04BA02 |
PubChem | CID 2955 |
DrugBank | DB00250 |
ChemSpider | 2849 |
ChEBI | CHEBI:4325 |
ChEMBL | CHEMBL1043 |
Chemical data | |
Formula | C12H12N2O2S |
Mol. mass | 248.302 gmol-1 |
(what is this?) (verify) |
Dapsone (diamino-diphenyl sulfone) is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It is also second-line treatment for prophylaxis (prevention) against Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii (formerly P. carinii) in HIV patients in whom CD4 counts are below 200/mm3.[1]
Dapsone is an odorless white to creamy-white crystalline powder with a slightly bitter taste, used in combination with pyrimethamine in the treatment of malaria.[2][3] Dapsone is commercially available in both topical and oral formulations. Topical dapsone is available in a 5% gel formulation that is sold under the brand name Aczone and is produced by Allergan. Oral dapsone is also available but is less commonly used than other sulfonamide antibiotics, many of which have a lower incidence of adverse effects.[4]
In the early 20th century, the German chemist Paul Ehrlich was developing theories of selective toxicity based largely on the ability of certain dyes to kill microbes. Gerhard Domagk, who would later win a Nobel Prize for his efforts, made a major breakthrough in 1932 with the discovery of the antibacterial prontosil red (sulfonamidochrysoidine). Further investigation into the involved chemicals opened the way to sulfa drug and sulfone therapy, first with the discovery of sulfanilamide, the active agent of prontosil, by Daniel Bovet and his team at Pasteur Institute (1935),[5] then with of dapsone independently by Ernest Fourneau[6] in France and Gladwin Buttle[7] in United-Kingdom.[8]
As an antibacterial, dapsone inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase.[9] Though structurally distinct from dapsone, the sulfonamide group of antibacterial drugs also work in this way.
When used for the treatment of skin conditions in which bacteria do not have a role, the mechanism or action of dapsone is not well understood. Dapsone has anti-inflammatory and immunomodulatory effects,[10] which are thought to come from the drug's blockade of myeloperoxidase. This is thought to be its mechanism of action in treating dermatitis herpetiformis.[11]
As part of the respiratory burst that neutrophils use to kill bacteria, myeloperoxidase converts hydrogen peroxide (H2O2) into hypochlorous acid (HOCl). HOCl is the most potent oxidant generated by neutrophils, and can cause significant tissue damage during inflammation. Dapsone arrests myeloperoxidase in an inactive intermediate form, reversibly inhibiting the enzyme. This prevents accumulation of hypochlorous acid, and reduces tissue damage during inflammation.[12][13][14][15][16]
Myeloperoxidase inhibition has also been suggested as a neuron-sparing mechanism for reducing inflammation in neurodegenerative diseases such as Alzheimer's disease and stroke.[17]
Though dapsone is an anti-inflammatory agent and not a steroid, it does not fit the usual definition of an NSAID. By definition, NSAIDs block cyclo-oxygenase as their primary mechanism of action, which dapsone does not do.
Dapsone was first synthesized by Fromm and Wittmann in 1908. 4,4'-Dinitrodiphenyl sulfide was oxidized to the sulfone in a solution of potassium dichromate, glacial acetic acid, and sulfuric acid. The nitro- groups on the sulfone were reduced with tin and concentrated hydrochloric acid, and the free base obtained by treatment with an alkali:[18]
As well as being used in leprosy, dapsone can also be used to treat mucous membrane pemphigoid,[19] (an autoimmune blistering disease of skin and mucous membranes), dermatitis herpetiformis and Linear immunoglobulin A dermatosis, (both blistering skin diseases that are effectively treated with a long-time treatment with dapsone), and other skin conditions including lichen planus. Dapsone is also used in the treatment of pyostomatitis vegetans, an oral manifestation of inflammatory bowel disease, commonly seen in patients with ulcerative colitis.
It is also sometimes used to prevent Pneumocystis pneumonia (PCP) in immunosuppressed patients and to treat idiopathic thrombocytopenic purpura.
It is used prophylactically to prevent Pneumocystis pneumonia and toxoplasmosis in patients unable to tolerate trimethoprim with sulfamethoxazole.[20]
Dapsone is also used to treat Brown recluse spider bites.[21] In presumed cases of brown recluse spider bites, dapsone is often used effectively, but clinical trials do not demonstrate similar effectiveness;[22] however, dapsone may be effective at treating many "spider bites" because many such cases are actually misdiagnosed microbial infections.[23]
Oral dapsone was one of the first medications used to treat moderate to severe acne vulgaris, and is still occasionally prescribed for the treatment of severe and abnormal acne (e.g. acne conglobata and acne fulminans).[24] Oral dapsone is generally reserved for cases where conventional treatments for severe acne, such as isotretinoin and first-line antibiotics, are found to be ineffective.[25] In December 2008, a 5% dapsone gel called Aczone was introduced to the prescription market as a topical treatment for moderate to severe acne.[1]. Preliminary reports suggest that topical dapsone is a safe and moderately effective acne treatment.[26]
Dapsone is administered orally as a 100 mg tablet or alternatively as 25 mg tablets.
To deal with dapsone-resistant leprosy cases, multidrug therapy was introduced by WHO in 1981; dapsone is administered along with rifampin and clofazimine or other antileprotic drugs.
Dapsone is administered transdermally (via the skin) as a gel 5% topical acne medication and available in 30-, 60-, & 90 gram tubes. In normal use, 0.5 grams (or "a pea sized amount") should be administered to the face per application twice a day.
Adverse effects[edit]
The dapsone hypersensitivity syndrome develops in 0.5-3.6% of persons treated with the drug, and is associated with a mortality of 9.9%.[27]
Effects on the blood[edit]
The most prominent side-effects of this drug are dose-related hemolysis (which may lead to hemolytic anemia) and methemoglobinemia.[28] About 20% of patients treated with dapsone suffer hemolysis [29] and the side-effect is more common and severe in those with glucose-6-phosphate dehydrogenase deficiency, leading to the dapsone-containing antimalarial combination Lapdap being withdrawn from clinical use.[30][31] Agranulocytosis occurs rarely when dapsone is used alone but more frequently in combination regimens for malaria prophylaxis.[32] Abnormalities in white blood cell formation, including aplastic anemia, are rare, yet are the cause of the majority of deaths attributable to dapsone therapy.[33][34][35]
Effects on the liver[edit]
Toxic hepatitis and cholestatic jaundice have been reported by the manufacturer. Jaundice may also occur as part of the dapsone reaction or dapsone syndrome (see below). Dapsone is metabolized by the Cytochrome P450 system, specifically isozymes CYP2D6, CYP2B6, CYP3A4, and CYP2C19.[36] Dapsone metabolites produced by the cytochrome P450 2C19 isozyme are associated with the methemoglobinemia side effect of the drug.
When used topically, dapsone can cause mild skin irritation, redness, dry skin, burning and itching. When used together with benzoyl peroxide products, temporary yellow or orange skin discolorations can occur.[37][38]
Other adverse effects[edit]
Other adverse effects include nausea, headache, and rash (which are common), and insomnia, psychosis, and peripheral neuropathy. Effects on the lung occur rarely and may be serious, though are generally reversible.[39]
Dapsone reaction[edit]
Hypersensitivity reactions occur in some patients. This reaction may be more frequent in patients receiving multiple-drug therapy.[40][41][42]
The reaction always involves a rash and may also include fever, jaundice, and eosinophilia.[43][44][45][46][47] In general, these symptoms will occur within the first six weeks of therapy or not at all, and may be ameliorated by corticosteroid therapy.[20]
Specific considerations[edit]
Certain patients are at higher risks of adverse effects when using dapsone. Some specific issues that should be considered are:[20]
- Related to the blood (a full blood count should be obtained prior to initiating therapy):
- Related to the liver (obtain liver function tests before starting therapy):
- Liver impairment
- Related to allergy:
- Sulfonamide allergy is associated with dapsone allergy
Patients with Diabetes mellitus have been seen to exhibit unexpectedly low HbA1c results when taking Dapsone, and HbA1c i an unreliable test in states of increased red cell turnover, e.g. a drug induced haemolytic anaemia.
- ^ Pocket Medicine: The Massachusetts General Hospital Handbook of Internal Medicine, by Sabatine, 3rd Edition
- ^ Croft, A. M. (Nov 2007). "Malaria: prevention in travellers". Clinical evidence 2007: 0903. PMC 2943798. PMID 19450348.
- ^ Alkadi, H. O. (2007). "Antimalarial drug toxicity: a review". Chemotherapy 53 (6): 385–391. doi:10.1159/000109767. ISSN 0009-3157. PMID 17934257.
- ^ Zhu, et al., YI; Stiller, MJ (2001). "Dapsone and sulfones in dermatology: overview and update". Journal of the American Academy of Dermatology 45 (3): 420–34. doi:10.1067/mjd.2001.114733. PMID 11511841.
- ^ J. et T. Tréfouël, F. Nitti et D. Bovet, « Activité du p.aminophénylsulfamide sur l'infection streptococcique expérimentale de la souris et du lapin », C. R. Soc. Biol., 120, 23 novembre 1935, p. 756.
- ^ E. Fourneau, Th. et J. Tréfouël, F. Nitti, D. Bovet, « Action antistreptococcique des dérivés sulfurés organiques », C. R. Acad. Sci., vol. 204, 1937, p. 1763.
- ^ G. Buttle, Y. Smith, G. Foster, « Treatment of streptococcal infections in mice with 4:4'diamino-dipheni-sulphone », Lancet, vol. 1, 1937, p. 133.
- ^ "Leprosy | 14 History of dapsone and dyes". Retrieved 2009-02-24. (1937)
- ^ "Medscape.com". Retrieved 2009-02-24.
- ^ Begon E, Chosidow O, Wolkenstein P (December 2004). "[Disulone]". Ann Dermatol Venereol (in French) 131 (12): 1062–73. doi:10.1016/S0151-9638(04)93842-2. PMID 15692440.
- ^ Uetrecht JP (1995). "Myeloperoxidase as a generator of drug free radicals". Biochem. Soc. Symp. 61: 163–70. PMID 8660393.
- ^ Bozeman P, Learn D, Thomas E. Assay of the human leukocyte encymes myeloperoxidase and eosinophil peroxidase. J Immunol Methods 1990; 126:125-133.
- ^ Bozeman P, Learn D, Thomas E. Inhibition of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase by dapsone. Biochem Pharmacol 1992; 44:553-563.
- ^ Stendahl O, Molin L, Lindroth M. Granulocyte-mediated release of histamine from mast cells. Effect of myeloperoxidase and its inhibition by antiinflammatory sulfone compounds. Int Arch Allergy Appl Immunol 1983; 70:277-284.
- ^ Kettle A, Gedye C, Winterbourn C. Superoxide is an antagonist of antiinflammatory drugs that inhibit hypochlorous acid production by myeloperoxidase. Biochem Pharmacol 1993; 45:2003-2010.
- ^ Kettle A, Winterbourn C. Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. Biochem Pharmacol 1991; 41:1485-1492.
- ^ Diaz-Ruiz A, Zavala C, Montes S, et al. (November 2008). "Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats". J. Neurosci. Res. 86 (15): 3410–9. doi:10.1002/jnr.21775. PMID 18615706.
- ^ E. Fromm, J. Wittmann (1908). "Derivate des p-Nitrothiophenols". Ber. 41 (2): 2264. doi:10.1002/cber.190804102131.
- ^ Rogers RS, Seehafer JR, Perry HO (February 1982). "Treatment of cicatricial (benign mucous membrane) pemphigoid with dapsone". J. Am. Acad. Dermatol. 6 (2): 215–. doi:10.1016/S0190-9622(82)70014-3. PMID 7037880.
- ^ a b c Rossi S, ed. (2006). Australian Medicines Handbook. Adelaide. ISBN 0-9757919-2-3.
- ^ Rees RS, Altenbern DP, Lynch JB, King LE (November 1985). "Brown recluse spider bites. A comparison of early surgical excision versus dapsone and delayed surgical excision". Ann. Surg. 202 (5): 659–63. doi:10.1097/00000658-198511000-00020. PMC 1250983. PMID 4051613.
- ^ Elston, DM; Miller, SD; Young Rj, 3rd; Eggers, J; McGlasson, D; Schmidt, WH; Bush, A (2005). "Comparison of colchicine, dapsone, triamcinolone, and diphenhydramine therapy for the treatment of brown recluse spider envenomation: A double-blind, controlled study in a rabbit model". Archives of dermatology 141 (5): 595–7. doi:10.1001/archderm.141.5.595. PMID 15897381.
- ^ Vetter R, Bush S (2002). "The diagnosis of brown recluse spider bite is overused for dermonecrotic wounds of uncertain etiology". Ann Emerg Med 39 (5): 544–6. doi:10.1067/mem.2002.123594. PMID 11973562.
- ^ Ross, et al., CM (1961). "The treatment of acne vulgaris with dapsone". British Journal of Dermatology 73 (10): 367–70. doi:10.1111/j.1365-2133.1961.tb14398.x. PMID 14494150.
- ^ "Dapsone and Acne Vulgaris". ScienceOfAcne.com. 2012-10-10. Retrieved 2012-08-17.
- ^ Draelos, et al., ZD; Carter, E; Maloney, JM; Elewski, B; Poulin, Y; Lynde, C; Garrett, S; United States/Canada Dapsone Gel Study Group (2007). "Two randomized studies demonstrate the efficacy and safety of dapsone gel, 5% for the treatment of acne vulgaris". Journal of the American Academy of Dermatology 56 (3): 439.e1–10. doi:10.1016/j.jaad.2006.10.005. PMID 17208334.
- ^ Zhang FR, Liu, H; Irwanto, A; et al. (Oct 24, 2013). "HLA-B*13:01 and the dapsone hypersensitivity syndrome.". N Engl J Med. 369 (17): 1620–8. doi:10.1056/NEJMoa1213096. PMID 24152261.
- ^ Jopling WH. Side-effects of antileprosy drugs in common use. Lepr Rev 1983; 54: 261–70.
- ^ Puavilai S, Chutha S, Polnikorn N, et al. (July 1984). "Incidence of anemia in leprosy patients treated with dapsone". J Med Assoc Thai 67 (7): 404–7. PMID 6512448.
- ^ http://www.who.int/medicines/publications/drugalerts/Alert_117_LapDap.pdf
- ^ Luzzatto L (August 2010). "The rise and fall of the antimalarial Lapdap: a lesson in pharmacogenetics". Lancet 376 (9742): 739–41. doi:10.1016/S0140-6736(10)60396-0. PMID 20599264.
- ^ Firkin FC, Mariani AF. Agranulocytosis due to dapsone. Med J Aust 1977; 2: 247–51.
- ^ Foucauld J, et al. Dapsone and aplastic anemia. Ann Intern Med 1985; 102: 139.
- ^ Meyerson MA, Cohen PR. Dapsone-induced aplastic anaemia in a woman with bullous systemic lupus erythematosus. Mayo Clin Proc 1994; 69: 1159–62.
- ^ Björkman A, Phillips-Howard PA. Adverse reactions to sulfa drugs: implications for malaria chemotherapy. Bull WHO 1991; 69: 297–304.
- ^ Ganesan, S; Sahu, R; Walker, LA; Tekwani, BL (April 2010). "Cytochrome P450-dependent toxicity of dapsone in human erythrocytes". J Appl Toxicol 30 (3): 271–5. doi:10.1002/jat.1493. PMID 19998329. Retrieved 7 March 2013.
- ^ Aczone(Dapsone) Package insert. Irvine CA: Allergan Inc; September 2008
- ^ http://pharmacistanswers.com/medications-for-acne-guide.html
- ^ Jaffuel D, et al. Eosinophilic pneumonia induced by dapsone. BMJ 1998; 317: 181.
- ^ Richardus JH, Smith TC. Increased incidence in leprosy of hypersensitivity reactions to dapsone after introduction of multidrug therapy. Lepr Rev 1989; 60: 267–73.
- ^ Kumar RH, et al. Dapsone syndrome—a five year retrospective analysis. Indian J Lepr 1998; 70: 271–6.
- ^ Rao PN, Lakshmi TSS. Increase in the incidence of dapsone hypersensitivity syndrome—an appraisal. Lepr Rev 2001; 72: 57–62.
- ^ Joseph MS. Hypersensitivity reaction to dapsone. Lepr Rev 1985; 56: 315–20.
- ^ Jamrozik K. Dapsone syndrome occurring in two brothers. Lepr Rev 1986; 57: 57–62.
- ^ Hortaleza AR, et al. Dapsone syndrome in a Filipino man. Lepr Rev 1995; 66: 307–13.
- ^ Tomecki KJ, Catalano CJ. Dapsone hypersensitivity: the sulfone syndrome revisited. Arch Dermatol 1981; 117: 38–9.
- ^ Kromann NP, et al. The dapsone syndrome. Arch Dermatol 1982; 118: 531–2.
External links[edit]


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Recycle old comics, books, and other materials to make something completely new.
Afternoon at the Movies: Happy Feet
This is the story of a little penguin named Mumble who has a terrible singing voice and later discovers he has no Heartsong. However, Mumble has an astute talent for something that none of the penguins had ever seen before: tap dancing. Though Mumble's mom, Norma Jean, thinks this little habit is cute, his dad, Memphis, says it "just ain't penguin." Besides, they both know that, without a Heartsong, Mumble may never find true love. As fate would have it, his one friend, Gloria, happens to be the best singer around. Mumble and Gloria have a connection from the moment they hatch, but she struggles with his strange "hippity- hoppity" ways. Mumble is just too different--especially for Noah the Elder, the stern leader of Emperor Land, who ultimately casts him out of the community. Away from home for the first time, Mumble meets a posse of decidedly un-Emperor-like penguins.
This movie has been rated: PG for some mild peril and rude humor
Afternoon at the Movies: Diary of a Wimpy Kid
To Greg Heffley, middle school is the dumbest idea ever invented. It's a place rigged with hundreds of social landmines, not the least of which are morons, wedgies, swirlies, bullies, lunchtime banishment to the cafeteria floor - and a festering piece of cheese with nuclear cooties. To survive the never-ending ordeal and attain the recognition and status he feels he so richly deserves, Greg devises an endless series of can't-miss schemes, all of which, of course, go awry. And he's getting it all down on paper, via a diary - "it's NOT a diary, it's a journal!" Greg insists, preferring the less-sissyfied designation - filled with his opinions, thoughts, tales of family trials and tribulations, and (would-be) schoolyard triumphs. "One day when I'm famous," writes Greg, "I'll have better things to do than answer peoples' stupid questions all day." So was born the Wimpy Kid's diary.
This movie has been rated: PG for some rude humor and language
Afternoon at the Movies: Tangled
After receiving the healing powers from a magical flower, the baby Princess Rapunzel is kidnapped from the palace in the middle of the night by Mother Gothel. Mother Gothel knows that the flower's magical powers are now growing within the golden hair of Rapunzel, and to stay young, she must lock Rapunzel in her hidden tower. Rapunzel is now a teenager and her hair has grown to a length of 70-feet. The beautiful Rapunzel has been in the tower her entire life, and she is curious of the outside world. One day, the bandit Flynn Ryder scales the tower and is taken captive by Rapunzel. Rapunzel strikes a deal with the charming thief to act as her guide to travel to the place where the floating lights come from that she has seen every year on her birthday. Rapunzel is about to have the most exciting and magnificent journey of her life.
This movie has been rated: PG for brief violence.
Afternoon at the Movies: Gnomeo and Juliet
Garden gnomes Gnomeo and Juliet have as many obstacles to overcome as their quasi namesakes when they are caught up in a feud between neighbors. But with plastic pink flamingos and lawnmower races in the mix, can this young couple find lasting happiness?
This movie has been rated: G
Teen Night - Belly Dancing
Learn basic Middle Eastern dance moves and rhythms, also known as belly dancing, from "Shahala" Liz Butler, instructor at Huntsville studio Nomadic Tapestry.
This is a teen only event!


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University Campus Suffolk (UCS) is a new kind of higher education institution – it works with range of partners along with two validating universities. Students are based across the six UCS centres at Ipswich (The Hub), Bury St Edmunds, Great Yarmouth, Lowestoft, Otley and Suffolk New College. UCS has five academic schools: applied social sciences; arts and humanities; business, leadership and enterprise; nursing and midwifery; and science, technology and health. All UCS courses, wherever they are delivered, fall under the academic authority of one of the five Schools. The schools work across the UCS campus network, and the validating universities of East Anglia and Essex oversee the quality of the courses offered.
£8,000 for bachelor degrees and £7,500 for two-year foundation degrees for full-time home/EU undergraduates in 2013-14.
See ucs.ac.uk/finance for 2014-15 figures, available from July 2013.
The National Scholarship Programme provides a fee waiver of £3,000 for both first and second year, eligibility criteria applies.
The Suffolk access champion scheme provides a fee waiver of up to £8,000 across first and second year, in return for mentoring activity in year 1 and e-mentoring in year 2.
Accommodation bursaries of £1,000 in year 1, £500 in year 2 and £500 in year 3 for students living away from the parental home. Eligibility criteria applies.
More information is available on the website.
Students can apply for accommodation at any point during their studies at UCS. Priority is given to first-year students. Athena Hall is the on-campus halls of residence at UCS. It is located just 300m from the Waterfront building in Ipswich. On-campus accommodation ranges from £91 to £102 a week for an en-suite bedroom in a shared flat; studio flats are £124 a week. Accredited accommodation across Ipswich starts at £69 a week. Most accommodation offered is based in Ipswich, but the accommodation office can assist with finding suitable accommodation at one of the other UCS centres.
The facilities at UCS Ipswich are based around a Waterfront campus that includes the landmark Waterfront building and Campus North. The Waterfront building has three lecture theatres, the newest of which seats up to 200, and 34 teaching rooms. UCS's newest addition is the James Hehir building. The UCS Union bar, Kai, is located on the ground floor, while the upper floors house brand new clinical skills facilities; biomechanics and physiology laboratories, including a specialised blood working area; microbiology and analytical laboratories; and an iLab.
Campus North is home to the UCS Library, which features a modern, IT-rich study environment, group-study pods and a completely silent study area. This area of the campus is also home to the School of Arts and Humanities, two cafes and the West building, which houses the Business Incubator and Atrium Studios, supporting students, graduates and local SMEs.
At UCS Bury St Edmunds and UCS Great Yarmouth, students have access to industry-standard recording studios, while UCS Lowestoft works closely with local teams through football development and coaching courses. UCS Otley boasts a state-of-the-art equine centre with an Olympic-standard approved indoor and outdoor school, a horse walker and a riding simulator. The extensive new facilities at Suffolk New College include construction workshops and a modern sports hall with football pitches (all-weather 3G).
UCS is 90 minutes from central London and within close proximity of a number of international airports and Harwich ferry terminal.
Tel: 01473 338833
Email: firstname.lastname@example.com
Web: ucs.ac.uk
Accommodation: email@example.com


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SKU: 310173 Weight: 0.05
In stock
List Price:$7.45 Your Price:$2.79 You Save: $4.66 (63%) International customers, please view our shipping page for information on additional shipping fees. CLICK HERE
CREATIVE IMPRESSIONS-Metal Turn Mounts. These fasteners are perfect for scrapbook layouts; greeting card and all paper craft projects. This package contains fifty 5/8x1/4in Assorted Primary Matte Painted Turn Mounts in blue; red; green; yellow; black and white. Imported.


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Being the country's number one selling lager, Carling is the obvious choice for a night in with your mates. Of course, drinking at home is never a substitute for going down the pub, so this set of Carling Pint Glasses is perfect to help you achieve a pub feel in your own home! More info
In stock
If you fancy a glass of Carling, there's no need to head down the pub for that freshly poured feel. The Carling Half Pint Glass features a nucleated base, printed in the shape of the Carling logo, for optimum head retention ensuring every sip tastes as good as the last. More info
In stock
To help you serve up a nice helping of Carling, this branded pitcher is CE marked at 4 pints, so you can be sure you're getting just the right dose! Great for hosting a soiree among friends, and even better for a great British barbeque, this pitcher is the perfect Carling companion. More info
More options
Some items in stock
Find the perfect Carling gift for the Carling beer fan in your life with our range of Carling merchandise, Carling gifts and Carling glassware. Our range of branded Carling glasses includes Carling pint glasses, Carling half pint glasses and Carling pitchers. Our selection of Carling lager glasses and Carling jugs is Carling official merchandise available with fast UK delivery for a last minute Carling gift.


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Private Label " Your Brand" in 6 simple steps
Welcome to HBH Pet Products
HBH began in 1988 as a plastics fabrication company.
One area of expertise was custom built tanks and filtration. As aquarium hobbyists' we found ourselves tinkering with innovative ideas. Then, as our interest and experience in the pet market continued, an opportunity to formulate and develop a revolutionary line of fish foods presented itself.
We began with just four foods in 1991, but have quickly grown over the last decade into one of the leading producers of aquarium foods. From the aquarium hobbyist to the first time pet owner, we proudly offer quality products at an excellent value.


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Featured Freeware: FreeMind
Like all mind maps, FreeMind for Windows and Mac gives you the flexibility to organize thoughts on a page as they connect to each other and to the larger picture. After all, not all minds reason in subheadings and bullet points. You shape, place, and name that master idea--called the root node in FreeMind--then create child or sibling spokes that relate to it.
FreeMind encompasses a fine range of features, including scads of icons and color formatting options to help you visually organize concepts. It also supports hyperlinks, which allow you to link Web sites and even documents to a … Read more


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Events for the month of March 2012 in Porter County
Cat Show - 03/10/2012 - 03/11/2012 Dunes Cat Fanciers will be hosting their Semi-Annual Non-profit Back to Back Championship and Household Pet Cat Show on March 10th & 11th. |
Art Exhibits
"Gathering Light" Mosaic Showcase at rTrail Collective Edge - 03/01/2012 - 04/08/2012 Join us for the Opening Night of our latest showcase. |
Leopold Bench Workshop - 03/03/2012 Leopold Bench Workshop at the Indiana Dunes State Park. |
Fire Departments of Westchester Township Exhibit - 02/18/2012 - 04/29/2012 Celebrate the history of Westchester Township fire departments at the all-new exhibit at Westchester Township History Museum, 700 W. Porter Avenue, Chesteton. February 18-April 29. |
MHA Antiques Show - 03/03/2012 - 03/04/2012 Annual antique exhibition. Come and explore the treasures! |
Passport to the Past Antique & Collectible Show - 03/03/2012 - 03/04/2012 Spend the day at this popular antique and collectible show. |
Porter County Home and Lifestyle Show - 03/09/2012 - 03/11/2012 Come and explore the possibilities at this popular home and garden exhibition. |
Spring Quilt Show - 03/31/2012 - 04/01/2012 String-A-Long Guild presents their 14thbiennial quilt show to be held at Porter County Expo Center. |
Food / Beverage
Eat Up Wine Down - First Thursdays - 11/03/2011 - 12/06/2012 $5 Food and Drink Specials at Valpo Dining Restaurants the First Thursday of EVERY Month. |
Performing Arts
Ballroom Dance Competition - 03/31/2012 Enjoy this popular annual ballroom dance competition. |
Lunchtime: Cabaret: The Grand Ladies of Country - 03/28/2012 Loretta Lynn, Dolly Parton, Tammy Wynette; the women who defined the role of female country singers of the 70's. |
Red Licorice - 02/24/2012 - 03/03/2012 The performance highlights a series of well-written monologues realized by students in which the player interacts with one or more imagined characters. |
Salute to the Stars, A Las Vegas Style Revue - 03/17/2012 Salute to the Stars features Jim Bulanda & Harley Hehr performing their musical and comedy salute to the stars Frank Sinatra, Dean Martin, Jimmy Durante, Tony Bennett, Frankie Valli, Jerry Lewis and many more. |
Sporting Events Participant
Blazers Softball Bowling Fundraiser Tournament - 03/04/2012 The Blazers Softball team of Chesterton will be hosting a no tap bowling tournament at Westchester Lanes to benefit their traveling softball team for the 2012 season. |
Brassie Golf Open House - 03/29/2012 - 04/19/2012 The Brassie Open House is a chance for golfers to play in a competitive Big Skin Game and enjoy an afternoon at the golf course. |
Sporting Events Spectator
Horizon League Tournament at VU - 03/02/2012 - 03/06/2012 Get all the information you need at www.indianadunes.com/horizon |
Swap Meets
R-Rides Swap Meet - 03/03/2012 Annual popular auto swap meet. This meet sells out! Don't miss it. |


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The Louisville-based non-profit that provides portable water purification systems for developing countries and disaster areas is changing its brand.
EDGE Outreach is now called WaterStep.
Founder Mark Hogg says the new name and logo better reflect the group's mission of providing clean drinking water where it's needed around the world, and is a reference to a shoe-recycling program that generates some of its operating funds.


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Cape Cod Mall, the Cape & Islands only indoor, regional shopper center, is anchored by Macy's Apparel, Macy's Men/Home and Sears, along with mini-anchors Best Buy, Marshalls and Barnes & Noble. The mall is home to nearly 100 shops and eateries including Banana Republic, LOFT, Sephora, J. Crew, and Victoria's Secret. A 400-seat international Food Court promises a little something for everyone and the mall is also home to Not Your Average Joe's, a full service restaurant, Chipotle Mexican Grill, and T. Murphy's Sports Bar & Grill as well as a Regal Cinemas 12 theater megaplex. Cape Cod Mall is conveniently located off of Routes 132 & 28 in the heart of the Hyannis retail shopping district. Whether you are searching for apparel, electronics, jewelry, shoes or dinner and a movie, you are bound to find it here! From the entire team at Cape Cod Mall, we hope to see you soon.
Cape Cod Mall is open today from 10am to 9pm.
Mall Office:
(508) 771-0201
Shopping Line:
(508) 771-0200
Mall Security:
(508) 790-1999
Extra 30% Off Clearance at The Children's Place!
The Children's Place at Cape Cod Mall
ALL Girls' Jeans, Jeggings, Shorts, Skirts, Skorts, Skimmers & Capris $12 & Under*
ALL Boys' Shorts, Jeans, Cargo Pants & Chinos $12 & Under*
ALL Graphic Tees $6.00 & Up*
Dressy Collection Now 30% Off**
Plus, Take an Additional 30% Off Clearance!**
Bare Minerals by Bare Escentuals at Cape Cod Mall
Book an appointment or simply walk in and receive a Lash Domination Mascara with ANY purchase.
Receive Ready Duo or Grand Finale Eye Shadow FREE with a purchase of $60 or more.
We will teach you how to make this pallet your own!
Call us at 508-775-1498 to book your appointment.
http://www.simon.com/mall/cape-cod-mall/stream/spring-up-your-look-1100606 Health, Bath & BeautyTeen Apparel & FashionWomen's Apparel & Fashion March 5, 2014Regina Pizzeria at Cape Cod Mall
Bring your receipt for a $20 Ryan Family Amusements Players Card (Cape Cod Mall location only) to receive a FREE Kids meal at Regina Pizzeria.
Bring your receipt for any Large Gourmet Pizza from Regina Pizzeria to receive a $3 Game Play!
http://www.simon.com/mall/cape-cod-mall/stream/march-special-1100372 Children's & Infant's ApparelMovie Theaters & CinemasMovies, Music & Video GamesRestaurantsToys & Games March 5, 2014Regina Pizzeria at Cape Cod Mall
Choose either Margherita (tomato sauce, fresh chopped basil, Mozzarella and Pecorino Romano cheese) OR Classoco pizza (large pepperoni, artichoke hearts, fresh mushrooms, Mozzarella and Parmesan cheese) for just $16.99 each!
http://www.simon.com/mall/cape-cod-mall/stream/march-pizza-deals-1076996 Restaurants February 28, 2014Sears Optical at Cape Cod Mall
Sears Optical
Buy One Get One FREE
Eyeglasses or Prescription Sunglasses
Offer Valid 1/8/14 to 4/8/14
Restrictions Apply.
See store associate for details.
http://www.simon.com/mall/cape-cod-mall/stream/buy-one-get-one-free-1010291 Health, Bath & BeautyJewelry, Watches & AccessoriesMen's Apparel & FashionSunglasses, Optical & EyewearWomen's Apparel & Fashion January 8, 2014Ryan Family Amusement at Cape Cod Mall
Bring your receipt for a $20 Ryan Family Amusements Players Card (Cape Cod Mall location only) to receive a FREE Kids meal at Regina Pizzeria.
Bring your receipt for any Large Gourmet Pizza from Regina Pizzeria to receive a $3 Game Play!
http://www.simon.com/mall/cape-cod-mall/stream/march-special-1100594 Children's & Infant's ApparelMovies, Music & Video GamesRestaurantsToys & Games March 5, 2014


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This Minute at Runco
NetFlix 4K Content for Planar UltraRes Series
Wednesday, November 06, 2013
This week it was announced the NetFlix is testing 4k video streaming and has posted a short video entitled "El Fuente 50 MP" which is described as "an example of 4k." We brought a PC with an internet connection into the lab to test the content on the Planar UltraRes 4k Ultra HD 84" LCD display.
In general, the content was not as good as the video loops we have demonstrated at DSE, InfoComm, and CEDIA Expo , which we know have been shot or rendered in 4k and are mastered for quality. That said, it was a significant improvement over what they showed in January 2013 at the Consumer Electronics Show (CES) and this latest effort shows real promise. We are watching with interest to see how the development progresses for streaming and 4k video distribution and this is an important step in that effort.
The ecosystem for 4k or Ultra HD content is continuing to develop with great resources available from stock video firms, on YouTube, and through marketing agencies, motion graphics studio, and video artists working in 4k. See previous blog posts for additional sources of high quality 4k content and stay tuned for additional posts in this series.
Planar UltraRes Displays Bring 4K Clarity to Professional Applications
Wednesday, February 27, 2013Planar's new Ultra HD resolution displays are uniquely designed to help professionals across industries reap value from high-resolution information
Today, at the Digital Signage Expo 2013 in Las Vegas, Planar Systems, Inc., a global leader in digital display technology, unveiled the breakthrough 84-inch Planar® UltraRes™ display product line, designed for ultra-high resolution commercial applications.
The new Planar UltraRes 4K displays provide native ultra–high definition resolution (3840 x 2160), outstanding image quality and a range of configurations. Planar UltraRes displays are ideal for professionals in a wide variety of commercial industries who require a large viewing area, very high pixel density and enterprise-level features that allow teams to collaborate around more immersive and detailed visual information.
"In commercial, academic and government settings there is a large and growing volume of ultra-high definition computer and video visual information—along with people making critical decisions based on that information," said Steve Seminario, senior director of product marketing for Planar Systems. "With Planar UltraRes, we're pleased to be leading the way for what we expect to be wide adoption of 4K resolution displays in these professional settings."
Making the Most of High-Resolution Information
Planar UltraRes 84-inch displays are designed for applications including
energy, geospatial, engineering and design, architecture, aerospace,
control room, collaborative conference room, medical imaging, science,
and digital signage, among others. Whether it's making a multi-million
dollar energy exploration decision, quickly rerouting electricity to
prevent an outage or producing stunning close-up video for a retail
store, Planar UltraRes 4K displays help businesses get the most impact
from their high resolution information.
"Our pioneering efforts in video wall technology have resulted in Planar being seen as one of the world's foremost authorities on 4K," said Jennifer Davis, vice president of marketing for Planar Systems. "For decades Planar has used ultra high definition content and has been a driving force in display resolutions, going back to our introduction of the industry's first 16:9 HD resolution rear-projection video wall displays. The exciting Planar UltraRes product line is a natural extension of our leadership in commercial markets and our expertise in resolutions beyond HD."
Planar UltraRes ultra HD displays offer the following benefits:
- Four times the pixel density: Planar UltraRes 4K displays offer four times the resolution of a full HD display. With a native resolution of 3840 x 2160, Planar UltraRes displays make it possible to view the most granular information with stunningly sharp focus.
- Advanced image quality: Planar UltraRes displays feature latest-generation LED-lit LCD technology, selectable dynamic contrast and local dimming for enhanced contrast. Planar UltraRes displays also support a full 60Hz refresh rate and10-bit color for an exceedingly life-like video experience.
- Advanced industrial design: Planar UltraRes displays provide a sleek design for both function and style. The displays have a slim metal bezel, wide range of digital connectivity options and incorporate failover power supply for 24x7 environments.
- Innovative mounting system: The Planar Profile™ Mounting System allows for an extremely slim profile when wall-mounted (about three inches) and provides a front service access mode. The Planar Profile™ Tiling Kit allows for optimized horizontal tiling of multiple Planar UltraRes displays and the industry's narrowest image-to-image gap for large format 4K displays.
- Breakthrough energy efficiency: Planar UltraRes displays come with an advanced energy-efficient design that utilizes edge-lit LED technology and passive cooling. The displays can automatically switch to standby mode when no source is detected and consume less than 0.5 watt of standby power. Planar UltraRes displays include no lead or mercury and are fanless and absolutely quiet.
- Modular for easy repair: Planar UltraRes displays have lockable, front service access, providing ease of service without removing the display from the wall.
Satisfying a Wide Range of Commercial Needs
Planar UltraRes displays come in three base models to suit a variety of commercial requirements:
- UR8450-LX: 2D landscape display ideal for conference and control rooms.
- UR8450-MX: 2D landscape and portrait, higher brightness model designed for digital signage and other higher ambient light environments.
- UR8450-3D: 2D and 3D landscape support, ideal for decision rooms where both 2D and 3D images and video are viewed.
Planar UltraRes 4K displays will be available through Planar's global network of authorized resellers and will begin shipping in the second calendar quarter of 2013. Visit Booth #407 at the Digital Signage Expo 2013 to learn more about Planar UltraRes and to see a demonstration. Additional information is available at www.planar.com.
Recent Posts
- Planar Announces Next Generation Clarity Matrix LCD Video Wall System
- NetFlix 4K Content for Planar UltraRes Series
- Finding 4K: Finding 4k Reference Content for the Planar UltraRes and Clarity Matrix LCD Video Walls
- Finding 4K
- Runco Xtreme Projection X200i Wows Visitors at CEDIA 2013
- Planar Provides Code for Easy Integration in a Savant Automation System
- LS12HBd Earns TOP PICK from Sound and Vision at CEDIA 2013
- Top Ten Workplace Movies
- I See You
- Game-Changing Live Action Cinematography
Explore the Magic of Runco
Next |
News & Events
Runco Adds Brilliant New Projector to Award-Winning LightStyle Series with LS-12HBd
17-Sep-2013 - Runco's best-selling LightStyle™ Series taken to new heights of brightness and scale, offering an affordable big screen video experience in virtually any room of th..... more ▶
New Runco XtremeProjection Series Lights Up the Big Screen Experience at Home
06-Sep-2012 - This exciting new lineup boasts high-performing video performance coupled with installation flexibility and 3D capabilities at an exceptional value. Indianapolis, IN &ndas..... more ▶


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Use the Airport Express as a local time server
You really need to define at least four or five upstream time servers, at a bare minimum. This subject is complex, but please see the discussion at http://twiki.ntp.org/bin/view/Support/SelectingOffsiteNTPServers.
Use the Airport Express as a local time server
I'm not trying to land a man on the moon, I just want my computer to be able to tell time. If it's off by a few seconds, or even a minute or two, I'm not going to jump off any buildings.
On my mac, I have the option under the Date and Time preference panel to have the time automatically set via time.apple.com. No Airport required. No firewall configuring required. Really, really simple.
The original hint was to use your base station to sync to upstream time servers, and then sync local machines to your base station. This is recommended practice, as it puts lower load on the upstream time servers.
You are technically correct - best practices would suggest multiple timeservers, but you are ignoring the fact that this community doesn't have those requirements.
Use the Airport Express as a local time server
If you want to use your base station as an NTP server, there's a good chance that it won't be able to get good time sync if you don't follow the recommendations, and if it can't get time sync then it can't provide time sync to any of your internal clients. |
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Business in Africa
Corporate Insights
ISBN 9780143528821 | 272 pages | 13 Feb 2013 | Penguin Global | 5.31 x 8.50in | 18 - AND UP
Summary of Business in Africa
Summary of Business in Africa
Reviews for Business in Africa
An Excerpt from Business in Africa
High-growth, high-return Africa, with much improved trading conditions, is the most sought after frontier destination for global investment today. However, there are 54 countries on the continent and even rigorous business plans can run aground on the unique and complex set of circumstances found in each of them. Business in Africa: Corporate Insights takes the reader to the coal face of doing business on the continent in articles by and interviews with people at the forefront of developments. They offer unique insights into the challenges and peculiarities of operating in Africa, and point out trends and likely future opportunities. Drawing on McKinsey & Associates, the Brenthurst Foundation and the Gordon Institute of Business Science for a picture of Africa's economic performance and future trends, contributions to the book also come from individuals such as veteran Africa analyst Dr. Duncan Clarke, Nigerian business leader Tony Elumelu, economic commentator Greg Mills of the Brenthurst Foundation, South African publisher Khanyi Dhlomo and Africa branding expert Doug de Villiers. The book also includes insights from global companies such as GE, Coca-Cola, Actis, Du Pont, Carlson Rezidor Hotel Group, Nando's and Anglogold Ashanti and household names in Africa such as MTN, MultiChoice, UBA, Webber Wentzel, Imperial Logistics, TBWA, Liberty Properties, Seed Co, Wilderness Holdings and SacOil. |
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Epic Ghost In Elevator Prank A little girl scares the sh*t out of some innocent people just looking to take the elevator up. 11/27/2012 12:00:00 AM 25,055
Dude Pranks Girlfriend With TV Ghost From The Ring This guy sets up a pretty good prank using a ghost coming out of the tv just like in the movie "The Ring". He wont be getting any for a month after that stunt... 7/7/2013 10:14:14 AM 23,967
The Most Easily Scared Guy In The World Everyday his co-workers scare the hell out of him. 12/27/2012 12:00:00 AM 23,152
Guy Lights Off Firecrackers In The School Library Want to scare the hell out of everyone in a quiet university library? Do this! 7/20/2013 11:07:07 AM 22,935
Scary Coffin In Elevator Prank The same guys that brought you the ghost in elevator prank last week are back with a dead guy in a coffin. 12/5/2012 12:00:00 AM 22,682
Deer Jumps Through Bus Windshield He could of just used the door like everyone else... 5/16/2013 10:56:24 AM 22,367
Funny Delivery Truck Train Prank Imagine being locked in the back of a delivery truck and getting stuck on the train tracks while you can hear a train coming. 4/17/2013 10:14:41 AM 22,188


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Officials report the waters of Indiana Dunes State Park are now open again. Those waters had been under a swimming advisory after officials were alerted by beach-goers who reported children coming out of the lake with what they described as a 'sticky substance' on them Monday afternoon. The Indiana Department of Environmental Management, and US Geological Survey both took samples Monday, and expect a report on their findings within a week. IDEM Spokesman Dan Goldblatt says the Coast Guard continues to investigate, but the substance, whatever it is, is not believed to have come from the shore or any stacks, and are also investigating the possibility if this incident is related to a glittery substance reported on vehicles and outdoor furniture in the 15-hundred block of Brown Avenue in Robertsdale earlier this month.
# # #
LAURA WALUSZKO Region News Team |
SCOTT ROSENBERG Region News Team |
BRENT BROWN Region News Team |
JAY STEVENS Region News Team |
KARL BERNER Region News Team |
ANNIE FOX Region News Team |


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Food allergies are becoming increasingly common around the world, with approximately 8% of all children and 5% of all adults having at least one food allergy. The most common food allergies in children include milk, egg, soy, wheat, peanut, tree nuts and seafood. In adults, the most common food allergies include seafood, fruits and vegetables (often as a result of the oral allergy syndrome).
Classically, there is no cure for food allergies. Avoidance of the culprit food is the best way to prevent symptoms. There have been many studies performed over the past 10 years that have attempted to cure food allergies - experimental treatments have included a variety of different forms of immunotherapy, meaning that the culprit food is given back to the allergic person in an attempt to force the immune system into tolerating the food, rather than reacting in an abnormal, allergic way.
Read more:
- All About Food Immunotherapy
- Does Oral Immunotherapy for Peanuts Really Work?
- All About Food Allergies


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Click any word in a definition or example to find the entry for that word
The motor oil gives good performance in all weather conditions.
The removal of trade restrictions could give the economy a substantial boost.
If you see him, will you give him a message from me?
They gave me all the instructions over the phone.
The answers are given on page 100.
This is the British English definition of give. View American English definition of give.
Change your default dictionary and thesaurus to American English.
an economic system based on the idea that different people or organizations share the creation and use of resources
BuzzWord ArticleBlog
A must for anyone with an interest in the changing face of language. The Macmillan Dictionary blog explores English as it is spoken around the world today.
global English and language change from our blog


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When I moved into my house (MANY years ago) only had ONE tree in middle of front yard. It provided verty little shade. Over the years that tree and others that were planted have become a source of almost total shade. LOVE it when weather gets HOT in the summer, cuz sun doesn't beat in thru windows much. Probably half of my front yard is now covered with moss. Have NO idea what kind(s) and have ZERO complaints about it. When grass needs to be cut... it's only half of the yard. Back in the fall, my crazy/GOOD neighbor took it upon himself to totally rip out a pretty weedy spot right outside my front door. Again, NO COMPLAINTS for this favor! Now spring is right around the corner... irises starting to poke up in that area. Almost half of THAT patch has healthy moss growing on it. Considering doing an herb garden there. Can I transplant patches/plugs of moss and hope to have it become a natural weed barrier between plants or small seeded areas? Know the moss has shallow roots. Thinking if a scratched up the soil around plants really well, and sliced off slabs of moss from other areas of the yard, it might take? Any tips or suggestions? | |||
Hi Chairlady...you do have a crazy/GOOD neighbor. LOL I found a cool site for you re: transplanting moss...looks pretty easy. http://homeguides.sfgate.com/c...lant-moss-60604.html Good luck. ~~~~~~~~~~~~ "I've decided to quit my job, drop out of society, and wear live animals as hats." | ||||
Good info mgt! Site said best to move in fall... well, spring is coming and thinking have nothing to lose!?! | ||||
Mosses are first stge plants that Ma Nature grows where nothing else will to provide the soil conditions necessary for more developed plants to grow. Many people think moss only grows in shady, acidic, moist soils yet I have seen moss growing in full sun, on concrete blocks (think lime), and on crushed dolomite (limestone). Take a good, in depth look at the soil where the moss is growing quite well and replicate those conditions where you want this moss to grow. Moss is very easy to grow if you provide the right conditions for it to grow.This message has been edited. Last edited by: KimmSr, The sign of a good gardener is not a green thumb, it is brown knees. | ||||
Here in humid Florida we have several kinds of moss. Irish moss, Reindeer moss, Spanish moss. I love the bright green moss that grows in between the stones in the center courtyard. There is no soil there but no sun either, when it's warm and moist outside it does the best. The reindeer moss just grows on top of the leaf litter under the trees in the woods. I'm not sure what kind this is but it's has cute little sprouts. Whether You Think You Can Or You Think You Can't..... You're Right - Henry Ford | ||||
The moss in my garden sprouts up like that, too. Must be part of it's flowering & seeding lifecycle, huh? I think reindeer moss is just the coolest. If you ever get the urge to gather some, I'd love to have some for floral arranging, etc. Chairlady, I don't think you have anything to lose, by transplanting the moss in the spring. I'd say, yep, nothing to lose so go for it. ~~~~~~~~~~~~ "I've decided to quit my job, drop out of society, and wear live animals as hats." | ||||
My sister has a great place in WV mountains. All around is this ground cover stuff that looks like mini pine trees? Have NO idea what it is, but just might dig some up next time I'm there and see if it like NJ. Seems to thrive in sunny, but mostly shaded areas under the trees. | ||||
Oooo I think I know what that is...my friend has it growing up at her cabin. Her hubby used to make her Christmas wreaths with it when he was there deer hunting. Might be called Princess Pine, but I'm not sure. ~~~~~~~~~~~~ "I've decided to quit my job, drop out of society, and wear live animals as hats." | ||||
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Yes, they could send the enforcement officers immediately to issue the citation.
I just realized that the Zinsco bus will accept thin 2 pole breakers.
This is a thin two pole 30 that would fit in your panel. The two pole thin 50 would be the same size. You can do what you want because of the Zinsco style bus.
It's still not real safe to pull out old breakers in this style of panel. They do get stuck and often have to be coaxed out.


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Just Around The Corner
"Somewhere, something incredible is waiting to be known." - Carl Sagan
"Somewhere, something incredible is waiting to be known." - Carl Sagan
"Whatever our souls are made of, his and mine are the same." - Emily Bronte
"First thoughts are not always the best." — Vittorio Alfieri
"I know that I'm intelligent, because I know that I know nothing." - Socrates
"Love is being stupid together." - Paul Valery
Haha, it is!
"Think in the morning. Act in the noon. Eat in the evening. Sleep in the night." - William Blake
"Friendship often ends in love, but love in friendship - never." - Charles Caleb Colton
so damn true...
It's true, sometimes we can try to be friends, but it's a really fake friendship.
"By all means, marry. If you get a good wife, you'll be happy. If you get a bad one, you'll become a philosopher." - Socrates
"I'm afraid that if you look at a thing long enough, it loses all of it's meaning." - Andy Warhol
Thanks for your support!! :)
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News Archive
February 21, 2005
Southern Methodist University holds a special, and ignominious, place in National Collegiate Athletic Association history, as the group's most-punished sports program and the only institution ever to receive the "death penalty."
In one fell swoop, the University of Minnesota could become SMU's equal.
February 21, 2005
Faculty panel rejects phasing out the teaching of ancient Greek -- and sees "incalculable" damage from the way cuts were proposed.
February 18, 2005
Measure would create new program for community colleges, though other institutions are eyeing the funds.
February 18, 2005
Bowing to faculty demands, Harvard President Lawrence H. Summers on Thursday released a transcript of his controversial remarks on women and science. He did so while releasing yet another apology for those remarks and as the head of the Harvard Corporation released a statement backing Summers.
February 18, 2005
Colleges have become "dramatically more market-oriented," and risk sacrificing important values to the quest for money, warns a report issued Thursday.
"Many academic leaders feel compelled to chase revenues and rankings rather than to focus their efforts on providing a high-quality education," says the report, "Correcting Course: How We Can Restore the Ideals of Public Higher Education in a Market-Driven Era," issued by the Futures Project, a higher education research group based at Brown University.
February 18, 2005
A New York court requires Cornell to make public some documents related to one of its state funded colleges.
February 18, 2005
A Government Accountability Office report released Friday finds that the average time foreign scholars and students must wait for a key federal visa review has shrunk to about two weeks from more than two months last year, according to the Associated Press.
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Do you run your business through a retail location? If you have a brick-and-mortar storefront then it's probably safe to assume that you're looking to target local consumers. The number 1 goal for any business with a retail location should be to build awareness within their local community. It doesn't matter if your business is located in a big city or the smallest of small towns your local community is going to provide you with your primary customers. Many businesses use things like signs in front of their store, local newspaper ads, and even radio ads to help generate awareness within their local community. What some businesses don't realize is that they can take those local marketing efforts online by optimizing their website and social media sites to generate local search traffic.
One of our clients is a local YMCA. They ONLY target the local community for YMCA membership. When they first brought us in to help them with social media marketing all that they had was a website. We helped them setup a local marketing strategy whereby everything they do online is optimized to attract local web traffic. For a business like the YMCA who provides a local service, it doesn't make sense to market to people living in another state OR even another county. This means they have to be highly targeted in their approach, something that is very achievable when you have the right strategy in place. Below are 4 ways to generate local search traffic. Each of these local marketing tactics was implemented at the YMCA. 90% of their traffic is from local residents!
Optimize Your Website to Generate Local Traffic
The first and most important step in generating more local search traffic for your small business is to optimize your website with local keywords. Do you have one of those fancy all Flash websites? Not good for local search… Do you have a website that's full of images and has minimal content? Not good for local search either… In order for your small business website to start moving up the search ranks for local keywords is to USE THOSE LOCAL KEYWORDS IN THE CONTENT OF YOUR WEBSITE.
If your business is located in San Diego and you sell womens shoes (yes, I was just watching an episode of 'Married with Children') then include the words "San Diego" in the content of your website. Instead of saying, "We have some of the best new styles in women's shoes around", say, "Our shoe store has some of the best new styles of women's shoes in San Diego". Just by adding the keywords "shoe store" and "womens shoes in San Diego" you will absolutely increase your web traffic because keywords like "women's shoes in San Diego" are probably high searched terms when it comes to women who are looking for shoe stores in the San Diego area. Adding local keywords to your website content will definitely help you generate local search traffic for your small business.
Include Local Keywords in Your Blog Articles
Have you setup a blog for your small business yet? If so, bravo to you! Blogging is a great way to generate more traffic for your website. By adding local keywords to your blog article content you can then generate more local search traffic for your small business. Just like adding local keywords to your website content, whenever you are writing a new blog article and it makes sense to insert your location, do it. If you serve multiple towns and boroughs don't be afraid to insert each of them in certain places throughout one article or many. Be sure not to go overboard and only insert local keywords if it's relevant. Once you get the hang of adding local keywords it becomes a natural part of your writing process.
Each time you publish a new article to your blog you are adding new local search terms. Search engines pick up on that and start ranking your site higher and higher for those local search terms, which means you're going to generate much more local search traffic for your small business.
Use Local Hashtags in Your Tweets
We actually just wrote an article about this local marketing tactic the other day. Using local hashtags in your tweets is a great way to generate more local traffic to your website and blog. By adding local hashtags like #Philadelphia #Missouri you can get your tweets in front of people who are following those hashtags on Twitter. Most likely if someone is following a local hashtag he/she lives or visits that local area. If that's the case then you have just effectively gotten your content in front of your target audience by adding a local hashtag to your tweets. If your tweet contains a link to your website or blog then a certain percentage of those people who see your tweet are going to click through to read your content.
Another great way to localize your social media is to add local keywords to your social media profiles.
Setup Profiles on Local Search Tools
Is your business on Google Places? Do you use foursquare, Yelp, or Facebook Places? If so, then you're on the right track when it comes to using local search tools and location marketing tools to generate more local traffic for your small business. Google Places is one of the best local search tools out there for small businesses. It's free, you can customize a profile for your business, you can create a Google Places Coupon, and you are leveraging the top search engine on the planet.
Have you seen the business listings that come up next to the Google Map when you perform a search on Google? Those are Google Places listings. They come up when someone uses local search terms in their Google search. If your business has a Google Place page and it's optimized for the local area, then your business will come up in that list (ahead of all other results!!).
First, you must claim your Google Places page. Then you can customize your Google Places profile. Be sure to include information about your products and services, links to your website, blog, and social media, and don't forget to include local keywords within the content of your Google Places profile. By adding local keywords and filling out the local information within Google Places your small business will start to come up in the local search results on Google. Google Places and other local search tools are great ways to generate more local search traffic for your small business.
Hopefully these four local marketing ideas will help you generate more local search traffic for your small business. In order to keep track of how effective you're in generating local search traffic you can use Google Analytics for reporting.


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The Shining: Now With More Robots!
I don't really like scary movies because I pissed myself in the theater during Harry Potter and the Sorcerer's Stone and all my friends still make fun of me. But I did happen to see The Shining in my youth. Remember the tricycle scene (if you don't I posted the original after the jump)? Well this is that scene recreated with the only thing that could possibly make it scarier -- robots. Now I'm not gonna say watching it made me pull a Potter here in my cube, but it did. And, uh-oh, I think a little WALL-E might have snuck out as well.
Hit the jump for the original scene from the movie.
Thanks to Rob (whose buddy actually made the video) and Daniel, now lets recreate the headspin scene from The Exorcist. OMG SCARY!
iRobot, a diabolical company best known for convincing millions of housewives to allow rug-munching robots into their homes, has now developed an air-filled shape-shifting robot that will climb into your bed and smother you while you sleep. Unveiled at the International Confer... / Continue →
This is a real-life Transformer (OmniZero.9, the brainchild of Takeshi Maeda) that can morph from a humanoid robot to a humanoid robot that can carry a person, to a wheeled cart. Just watch how scary it is when it moves. If I didn't know better, I'd swear there was a little p... / Continue →
I have no idea what I'm watching, but I'll tell you one thing: I don't like the look of it. This red sore on my palm either. And I don't even play video games! What are you trying to insinuate? That sock is a liar! Youtube Thanks to Bro_mole, who is ready to stomp those l... / Continue →


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Submit News
DARPA Announces Nanotube Anti-radiation Pill
Levi Beckerson
January 29, 2008 12:00 PM
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The carbon-sink anti-radiation pill was proposed in Tim Cain's 1997 computer game Fallout. The third official title in the series will debut later this year.
(Source: Bethesda)
Radiation sickness drug in the form of carbon nanotubes gets DARPA's attention
"More than half of those who suffer acute radiation injury die within 30 days, not from the initial radioactive particles themselves but from the devastation they cause in the immune system, the gastrointestinal tract and other parts of the body. Ideally, we'd like to develop a drug that can be administered within 12 hours of exposure and prevent deaths from what are currently fatal exposure doses of ionizing radiation," explains James Tour, Rice University's Chao Professor of Chemistry and director of Rice's Carbon Nanotechnology Laboratory.
Tour and his colleagues have been awarded a $540,000 grant by the Defense Advanced Research Projects Agency (DARPA) to do further research on a carbon nanotube (CNT) based drug for the treatment of radiation sickness.
Radiation sickness is so deadly because the ionizing affect of radiation alters the balance between protons and electrons in molecules. The process often creates free radicals. Free radicals are highly reactive molecules and in the case of radiation poisoning, cause disruption in living cells. The disruption often triggers a domino effect, propagating widespread damage throughout the organism's physiology.
Rensselaer Polytechnic's CNT-based cancer, disease and toxin treatment
, which creates reactive oxygen to disable target proteins, Tour's group's Nanovector Trojan Horses (NTH) soaks up the harmful free radicals created by radiation poisoning. To make the simple drug, single walled CNTs are coated with two common food preservatives, butylated hydroxyanisole and butylated hydroxytoluene. Tour explains that the same properties that make the compounds good preservatives, their ability to soak up free radicals, also makes them ideal for the treatment of radiation exposure and sickness.
In the lab, the NTH treatment has been tested on mice and was shown to enhance protection when the mice were exposed to lethal doses of ionizing radiation when given the drug prior to exposure. Though the tests were not done as a treatment for exposure, DARPA took an interest in the technique and awarded the group with the grant, which specifies a very short nine-month study. "They are very interested in finding out whether this will work in a post-exposure delivery, and they don't want to waste any time," said Tour.
NTH shows great promise, preliminary testing showing the drug to be more than 5,000 times more effective at mitigating the effects of radiation injury than most available drugs. Tour's group is also looking into the possibility of NTH being useful in preventing the harmful side effects of radiation therapy for cancer patients.
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RE: Extremely misleading headline. It has no basis in reality and should be removed.
Misty Dingos
Misty Dingos
I wasn't going to say anything more about this article than what I have already have but JD you need an answer. And because I am a nice person I will help you out! How lucky your are!
First. Get some hand cream. Ringing your hands like you are you are going to need it. Get an industrial size too.
Global climate change is called the
. The climate has never been stagnant. Never been static, like you have been spoon fed by the eco-nuts and Al Goreski. Get used to it. Use some hand cream now, we will wait for you.
Nope don't pay taxes like we did in the good old days. Oh and guess what we actually have representation now too! Wait a second there. What was the Boston Tea Party about not taxation, no taxation without representation. We fixed that if I remember right. If you don't like who represents you vote against them or run yourself. Some one please hand JD a hanky for him to cry in now.
So you are thinking that there is more pollution (in general). Well the truth is that the air is cleaner in the USA than it has been since the early 60's. The water is cleaner and the dirt is cleaner and the Bald Eagle isn't endangered anymore either. There are so many deer in New Jersey that they have to hire guys to kill them! If you would have said in 1970 that one of New Jerseys big issues in 2008 would be whitetail over population people would have laughed in your face.
Yes let's thank God for great journalists. Like Dan Rather, Mary Mapes, Mike Barnicle, Nada Behziz, Jayson Blair, Paul Bradley, Fox Butterfield oh I could go on and on but I won't. Every one of these 'journalists' was caught out right lying or fabricating stories. Great examples of a free press. Yes freedom of speech is easily one of the most important of our freedoms. I will leave a link for those of you interested in this laundry list of miscreant journalists. My take on this is that with people like these as journalists it will not be long before the first amendment is amended with extreme restrictions. Just to reign in the run amuck journalism that we see today.
I can see now that JD has had enough truth for one day. Some one please tuck him into bed and the rest of us adults will just have to soldier on without him until he wakes up from his nap and has some juice and cookies.
RE: Extremely misleading headline. It has no basis in reality and should be removed.
When I said Thank God for journalists, I was being sarcastic. You must have missed that. You guys are quite right to try and correct me about taxation without representation.
However, let's not kid ourselves. They were angered about the rate which they were being taxed, which was more than England was being taxed at the time. You are quite right though that they weren't being represented in the decisions made in England that directly affected them (in fact their diplomats were thrown out of the courts I believe).
Some of the responses to my post were rather rude. Particularly yours Misty. I think that kind of incivility is unnecessary. Whether or not the weather is changing is not a question.
So I pose these questions to you:
Why do you not believe these scientists who study the melting polar caps? Are they not more educated in their field of study than you are?
They say that these caps are melting at a crazy fast rate, and that it's been a VERY long time since some of this melting ice has seen sunlight. Now explain to me how the average temperature can raise 6 degrees in under a century and possibly think it isn't a result of all the deforestation, burning fossil fuels, and polluting the oceans.
Will the earth survive global warming? Undoubtedly. Volcanoes used to rule the surface, and life prospered. The problem here is that since that time, we have become more numerous. I am telling you that YES, I believe we have a greater number of people and a greater ability to impact the earth than ever before.
There have been some great civilizations that have come and gone. I think about Rome and the Mayans, the Chinese Dynasties, and the Nile River Valley. But never before have we known so much about bacteria, viruses, balancing our diets, mass production of food and fuel, etc. than the last century.
We are in the technological age my friend. China is just now taking its turn in the industrial revolution. Technology has made us more abundant, and that's a problem. Maybe you need an industrialized breath mint for your morning breath. It's time to wake up.
"So, I think the same thing of the music industry. They can't say that they're losing money, you know what I'm saying. They just probably don't have the same surplus that they had." -- Wu-Tang Clan founder RZA
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NWebber commented about 9 hours ago
Alessandra Rizzotti commented about 11 hours ago
Jj Mk commented about 11 hours ago
Is college designed to give students job skills, or to encourage them to study subjects they're passionate about? It's a question that can incite endless debate, but according to the 46th annual Freshman Survey—a project of the Higher Education Research Institute at UCLA—students increasingly believe it's the former.
The survey, the largest of its kind, polled nearly 204,000 full-time freshmen entering 270 four-year colleges and universities last fall. Researchers found that 85.9 percent of freshmen said they're in college "to be able to get a better job." Prior to the recession, freshmen consistently answered "to learn more about things that interest me" as the major reason they pursued higher education.
Students pursuing different majors offered strikingly different motivations for seeking college degrees. Roughly 88 percent of freshmen planning to major in science, technology, engineering, or math, and 92 percent of students majoring in business, cited improved job prospects as the most important factor. Meanwhile, a relatively paltry 73 percent of humanities majors said job skills are most important to them.
Also predictably, 85 percent of business students said they're in school "to be able to make more money" compared to just 56 percent of humanities majors. But the good news for humanities majors is that, although their overall salaries remain lower than STEM and business majors, salaries for those grads saw the biggest percentage jump last year.
The recession has reshaped the entire nation, so it's not surprising that students are reacting by changing their priorities. Just as Americans who grew up during the Great Depression were shaped by economic hardship, the current generation of students are understandably motivated by a desire for financial stability.
Photo via (cc) Flicker user David Berkowitz