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Phase II Trial of Alemtuzumab (Campath) and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in Relapsed or Refractory Diffuse Large B-Cell and Hodgkin Lymphomas
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- Studies conducted at the National Cancer Institute suggest that certain chemotherapy drugs may be more effective if given by continuous infusion into the vein rather than by the standard method of rapid intravenous injection. One combination of six chemotherapy drugs, known as EPOCH-R, has had a high degree of effectiveness in people with certain kinds of cancer.
- Recent evidence also indicates that the effects of chemotherapy may be improved by combining the treatment with monoclonal antibodies, which are purified proteins that are specially made to attach to foreign substances such as cancer cells. A monoclonal antibody called campath (alemtuzumab) has been manufactured to attach to a protein called CD52 that may target tumor cells or the surrounding inflammatory cells.
- Researchers are interested in developing new treatments for large B-cell lymphoma or Hodgkin lymphoma that can best be treated with chemotherapy. This protocol is specifically for people with diffuse large B-cell or Hodgkin lymphomas that have not responded to standard treatments.
- To test whether giving campath (alemtuzumab) in combination with continuous infusion EPOCH-R chemotherapy will improve the outcome of lymphoma treatment.
- Individuals 18 years of age and older who have large B-cell lymphoma or Hodgkin lymphoma that has not responded well to standard treatments.
- During the study, patients will receive standard EPOCH-R chemotherapy, which includes the following drugs: etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab. The additional drug, campath, will be given by IV infusion on the first day of treatment over several hours.
- When the campath IV infusion and rituximab IV infusion are complete, the drugs doxorubicin, etoposide, and vincristine will each be given by continuous IV infusion over the next 4 days (that is, continuously for a total of 96 hours). Cyclophosphamide will be given by IV infusion over several hours on Day 5. Prednisone will be given by mouth twice each day for 5 days.
- Patients may be given other drugs to treat the side effects of chemotherapy, to prevent possible infections, and to improve white blood cell counts.
- The campath-EPOCH-R therapy will be repeated every 21 days, as a cycle of therapy, for a total of 6 cycles. Following the fourth and sixth treatment cycles (approximately weeks 12 and 18) of campath-EPOCH-R treatment, study researchers will perform blood tests and CT/MRI scans on all patients to assess their response to the treatment.
Condition | Intervention | Phase |
Hodgkin Lymphoma Diffuse Large B-Cell Lymphoma |
Drug: Cylcophosphamide Drug: Etoposide Drug: Alemtuzumab Drug: Doxorubicin Drug: Prednisone Drug: Filgrastim Drug: Rituximab Drug: Vincristine |
Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Non-Randomized Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment |
Official Title: | Phase II Trial of Alemtuzumab (Campath) and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in Relapsed or Refractory Diffuse Large B-Cell and Hodgkin Lymphomas |
- Assess response, progression free survival (PFS) and overall survival (OS) in relapsed/refractory DLBCL and Hodgkin lymphoma. [ Time Frame: 5 years ] [ Designated as safety issue: No ]
- Correlate clinical outcomes with microenvironment/stromal molecular signatures by gene expression profiling and immunohistochemistry on study and at relapse after DA-EPOCH-RC. [ Time Frame: 5 years ] [ Designated as safety issue: No ]
Estimated Enrollment: | 47 |
Study Start Date: | October 2009 |
Estimated Study Completion Date: | September 2014 |
Estimated Primary Completion Date: | September 2014 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Active Comparator: Group 1 |
Drug: Cylcophosphamide
750 mg/m2 day 5 each cycle
Drug: Etoposide
50 mg/m2 days 1-4 each cycle
Drug: Alemtuzumab
30 mg day 1 each cycle
Drug: Doxorubicin
10 mg/m2/day days 1-4 each cycle
Drug: Prednisone
60 mg/m2 BID days 1-5 each cycle
Drug: Filgrastim
480 mcg/day for approx. 10 days each cycle
Drug: Rituximab
375 mg/m2 day 1 each cycle
Drug: Vincristine
0.4 mg/m2/day days 1-4 each cycle
Detailed Description:
Two signatures of the microenvironment were recently identified that are predictive of outcome in patients with newly diagnosed DLBCL treated with R-CHOP. These signatures, called stromal 1 and stromal 2 , are associated with genes expressed by infiltrating mononuclear cells. The stromal 2 signature, which includes genes associated with angiogenesis, is predictive of an inferior outcome. Based on these observations, we are interested in targeting the reactive cells in the microenvironment as a therapeutic strategy in patients with relapsed and refractory DLBCL. Along the same principles, we are also including patients with relapsed Hodgkin lymphoma (HL). The surrounding reactive cells around Hodgkin Reed Sternberg (HRS) cells are now not thought to be bystander cells and they appear to provide important survival signals to HRS cells.
- CD52 is one such promising target that is highly expressed in most of these infiltrating cells and on most DLBCL although not on HRS cells specifically. Anti-CD52 antibodies may have therapeutic value by depleting reactive B and T cells, and monocytes from the microenvironment.
- The dose of alemtuzumab in combination with DA-EPOCH is 30 mg IV, as determined by a prior study done in patients with untreated peripheral T-cell lymphoma. The main toxicities of this combination are myelosuppression and opportunistic infections.
- An important component of this study will be to obtain tumor tissue for gene expression profiling and to assess microenvironment signatures and look at other molecular signatures and targets before treatment and in patients who progress and ultimately correlate response and outcome with these various end-points.
- Assess response, progression free survival (PFS) and overall survival (OS) in relapsed/refractory DLBCL and Hodgkin Lymphoma.
- Correlate outcome with gene expression profiling and immunohistochemistry of tumor tissue (in particular looking at microenvironment/stromal molecular signatures).
- Previously treated orrefractory classical large B-cell lymphomas, Grey-zone lymphoma and Hodgkin lymphoma, including Lymphocyte predominant Hodgkin Lymphoma (LPHL).
- Age greater than or equal to 18 years with adequate organ functions.
- HIV negative and no active CNS lymphoma.
Study Design:
- Patients will receive 30mg of Alemtuzumab on day 1 of therapy, followed by Rituximab on day 1 and dose-adjusted EPOCH chemotherapy days 1-5, up to six cycles of therapy.
- Tumor biopsies will be done before treatment, after 1 cycle of therapy and at relapse.
- It is anticipated that up to 10-15 patients per year may be enrolled onto this trial. Thus, accrual of up to 44 evaluable patients is expected to require approximately 3-4 years.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
- Previously treated orrefractory classical large B-cell lymphomas, Grey-zone lymphoma and Hodgkin lymphoma, including Lymphocyte predominant Hodgkin Lymphoma (LPHL).
- Confirmed pathological diagnosis by the Laboratory of Pathology, NCI.
- Age greater than or equal to 18 years.
- ECOG performance 0-2
- Laboratory tests: ANC greater than or equal to 1000/mm(3), platelet greater than or equal to 75,000/mm(3). Creatinine less than or equal to 1.5 mg/dL or creatinine clearance greater than or equal to 60 ml/min; AST and ALT less than or equal to 5 times the ULN. Total bilirubin < 2.0 mg/dl except < 5mg/dL in patients with Gilbert s (as defined as > 80% unconjugated hyperbilirubinemia without other known cause); unless impairment due to organ involvement by lymphoma.
- Active symptomatic ischemic heart disease, myocardial infarction or congestive heart failure within the past year. If ECHO is obtained, the LVEF should exceed 40%.
- HIV positive, because of the unknown effects of combined therapy with chemotherapy and an immunosuppressive agent on HIV progression.
- Female subject of child-bearing potential not willing to use an acceptable method of birth control (i.e. a hormonal contraceptive, intrauterine device, diaphragm with spermicide, condom with spermicide, or abstinence) for the duration of the study and two years beyond treatment completion.
- Female subject pregnant or breast-feeding. Confirmation that the subject is not pregnant must be established by a negative serum beta-human chorionic gonadotrophin (beta-hCG) pregnancy test result obtained during screening. Pregnancy testing is not required for women without childbearing potential.
- Male subject unwilling to use an acceptable method for contraception for the duration of the study and one year beyond treatment completion.
- Invasive or active malignancy in past 2 years.
- Serious concomitant medical illnesses that would jeopardize the patient s ability to receive the regimen with reasonable safety.
- Active CNS lymphoma. These patient have a poor prognosis and because they frequently develop progressive neurological dysfunction that would confound the evaluation of neurological and other adverse events.
- Systemic cytotoxic therapy within 3 weeks of treatment.
Contact: Margaret Shovlin, R.N. | (301) 594-6597 | firstname.lastname@example.com | |
Contact: Wyndham H Wilson, M.D. | (301) 435-2415 | firstname.lastname@example.com |
United States, Maryland | |
National Institutes of Health Clinical Center, 9000 Rockville Pike | Recruiting |
Bethesda, Maryland, United States, 20892 | |
Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office (888) NCI-1937 |
Principal Investigator: | Wyndham H Wilson, M.D. | National Cancer Institute (NCI) |
Additional Information:
Responsible Party: | National Institutes of Health Clinical Center (CC) ( National Cancer Institute (NCI) ) |
ClinicalTrials.gov Identifier: | NCT01030900 History of Changes |
Other Study ID Numbers: | 100011, 10-C-0011 |
Study First Received: | December 11, 2009 |
Last Updated: | November 27, 2013 |
Health Authority: | United States: Federal Government |
Keywords provided by National Institutes of Health Clinical Center (CC):
Immunosuppression Microenvironment Hodgkin Lymphoma |
B-Cell Lymphoma Microarray Diffuse Large B-Cell Lymphoma |
Additional relevant MeSH terms:
Hodgkin Disease Lymphoma Lymphoma, B-Cell Lymphoma, Large B-Cell, Diffuse Neoplasms by Histologic Type Neoplasms Lymphoproliferative Disorders Lymphatic Diseases Immunoproliferative Disorders Immune System Diseases Lymphoma, Non-Hodgkin Doxorubicin Alemtuzumab Rituximab Etoposide |
Prednisone Vincristine Lenograstim Campath 1G Antibiotics, Antineoplastic Antineoplastic Agents Therapeutic Uses Pharmacologic Actions Antineoplastic Agents, Phytogenic Glucocorticoids Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Physiological Effects of Drugs Antineoplastic Agents, Hormonal Anti-Inflammatory Agents |
ClinicalTrials.gov processed this record on March 10, 2014


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V.C. Pirates vs. Fullerton Hornets
The Pirates are champions
A lot has changed in the eight years since Ventura College women's basketball team last played on the final Sunday of the season.
But the Pirates' pride still shines through when protecting their own basket.
"We know we can score," said sophomore Erika Ward, "but we pride ourselves on defense.
"Coach says offense sells tickets."
And a raucous crowd Sunday afternoon at Cal Lutheran's Gilbert Center bore witness to what defense accomplishes.
Chanelle Brennan provided the offense with a sweltering 33-point, five-rebound performance and the Pirates banded together with their brand of defense to beat Fullerton, 59-47, in the state championship game.
Kris King and Amanda Padilla had eight points apiece and Gabrielle Conn had 12 rebounds as Ventura (34-1) earned its record sixth state championship on county soil, eight years after its previous banner, by holding powerful Fullerton (32-2) to 27.9 percent shooting.
"We put it back on the map," said Padilla. "Ventura College has another championship ... and it's great to be a part of it."
Scanning from 5-foot-5 Padilla to 5-foot-11 King, Ventura may not seem like an imposing defense to the naked eye. But the Pirates were the top defense in the state statistically, before proving they were also the top team Sunday.
"Height isn't everything," said King. "We have heart."
A year after racing unbeaten to a Final Four loss to eventual champion Pasadena City, Ventura's sophomore class earned redemption, as the 11-player roster joined a select sisterhood of 50 former players with special jewelry.
"After losing last year in the Final Four," said Ward, "this state championship means the world to us."
After a pair of 34-1 seasons, the six sophomores completed their VC careers a stellar 68-2, the second best record in school history behind the Class of 1997 (71-1).
The 12-point margin of victory was the largest of the program's six state final wins.
"It's like a dream come true," said Ward. "I can't express what it means to me."
Destainee Hollis-Rudison had eight points, Taiyande Huskey had seven points and five other players had six points for Fullerton (32-2), which went undefeated against its schedule, save two losses to Ventura.
Brennan, the Most Valuable Player, was joined on the all-tournament team by Padilla, Huskey and Danielle Ekno of Fullerton, Mone Peoples and Marlee Rice of San Francisco and Charlene Popoff of Santa Rosa.
Padilla splashed a 3-pointer and Ward found Brennan for a 3-point play as Ventura, to the roaring approval of the partisan crowd, scored the first 10 points.
But Fullerton coach Debi Woelke turned to her loaded bench to take a lead with a 16-5 run on Hollis-Rudison's high-low pass for Ebony McClain to finish.
"Their second group is as good as most teams' first group," said Ventura coach Ned Mircetic. "They're the deepest team in the state. They can throw so many different looks at you. It took us a while to adjust."
Conn had struggled to find consistent playing time after pulling down 18 rebounds in a game during the first weekend of the season.
"That's honestly what I wanted to do," said Conn. "I'm a dominant rebounder and that's my role on this team."
The 5-foot-9 freshman piled up 21 rebounds in the semifinal and final.
"Those were big rebounds," said Mircetic. "Those were hard-fought rebounds."
Padilla's last-second 3-pointer bounced in to give the Pirates a 22-21 halftime lead.
It was never relinquished as Brennan scored 13 of her points in Ventura's banner-raising 17-5 run, bookended by two rare Brennan 3s, which lifted the Pirates ahead 49-36 with 8:07 to play.
The Ventura High product had 11 3s in the previous 34 games.
"She had an unbelievable weekend," said Ward of Brennan. "We're blessed to have her as a teammate."
Fouled while dribbling out the clock, sophomore guard Brenda Van Someren stood at the free-throw line, focused on the rim, as the celebration erupted on the VC bench.
"They were already jumping up and down on the bench," said Van Someren. "I had to make them."
As the team gathered in the locker room for a final "We Play Hard" chant, the coaches reminded the players to celebrate safely.
But title-winning teamwork apparently doesn't end with the championship season.
"Don't worry, coach," Van Someren answered. "We take care of each other."

subset: commoncrawl


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Debbie Squires, the infamous Michigan Elementary/Middle School Principals Association bureaucrat who told a Michigan legislative committee that parents may not know what is best for their children is now saying they should "stay informed" and "voice their concerns to legislators," according to Hometownlife.com.
Squires was addressing a group focused on school aid and urged attendees to talk to legislators to stop school choice legislation, such as the parent trigger or expanded for-profit options.
Earlier this year, Squires came under fire for telling the House Education Committee that while parents may want what is best for their children, they may not always know what actually is best. Because, you know, parents don't know their kids. But bureaucrats do!
"Educators go through education for a reason. They are the people who know best about how to serve children. That's not necessarily true of an individual resident. I'm not saying they don't want the best for their children, but they may not know what actually is best from an education standpoint," she said.
"Wow, parents don't know what's best for their child," a stunned Tom McMillin, committee chairman, said.
"I said they may want what's best for their child, but they may not know. And they may not have the capabilities…" Squires responded.
But now, she wants those dummies to contact their legislators to say her schools need more money.
Kyle is Founder and CEO of Education Action Group Foundation, a non-partisan non-profit organization with the goal of promoting sensible education reform and exposing those with a vested interest in maintaining the status quo.


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Color of Woman - Episode 18
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Byun So Ra (Yoon So Yi) comes from an ordinary background, but she works very hard. Her boyfriend cheats on her with her friend and her dreams of becoming a professor fall apart when she reports another professor for embezzelment. She ends the relationship and joins a cosmetics company and clashe... More info...
Category: TV Shows - International / Comedy TV Int / Color of Woman Interactions


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Message Category: Let's Try to Get Along Topic: Chuck "Local Marathon Whore" Engle
You would've made an excellent attorney! (or should I say..."Juris Doctor"?)
It's pretty amusing how some people go through great lengths to bad-mouth a person they've never even met. Ever heard of the phrase 'To each his own'?
Seriously, fellas...get a life.
Post a reply on the Bulletin Board
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The next best thing to Mickey Rourke winning an Oscar is probably adopting a new puppy and naming it Oscar, which is just what Mickey might be up to.
Radar Online reports today that the Academy Awards nominee, who last week said goodbye to his beloved pooch of 18 years, Loki, plans to welcome a new Chihuahua home soon - and he's naming the furball "Oscar." Awwwoof!
"Mickey has other dogs but he misses Loki terribly," says a friend of the star. "He doesn't want to wait long, either - he wants to get his new pooch this week. The new dog won't replace Loki, but by naming it Oscar, Mickey says he'll make his comeback year even more special." This sounds like a therapist-approved move, Mick.
While it's certainly ironic to name a new pup after the awards show that snubbed you, it's also a sign of Rourke's good nature. In fact, "The Wrestler" actor seems to have nothing but kind words for the Best Actor winner Sean Penn. The co-nominees were seen hugging it out at the Vanity Fair post-awards party.
But you know what they say, a dog will always be Mickey's best friend.


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- Home
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- Item# 39318
Gun Cleaning Kit for Dummies
Lowest Price Guarantee
If within 30 days of your online purchase at Kotulas.com, you find the identical product nationally advertised for less by one of our competitors, we will refund to you 110% of the difference!
Nationally advertised low prices found online must be printed out completely with proof of competitor's name and the offer's expiration date clearly visible. To receive your refund, please mail a copy of the advertisement with the offer's expiration date visible, together with a copy of your invoice to:
Kotula's Ecommerce Marketing
P.O. Box 1499
Burnsville, MN 55306-6936
Valid on retail price of item only, not on shipping and/or handling charges. No close-outs, misprints, price quotes, coupons, rebates, auction websites or liquidations. Also not valid on Member Club pricing. Item must be identical make and model#. Competitor product must be available and in-stock at the time of claim. Please allow 6 weeks for processing.
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This kit can prevent the kind of tragic accident we read about all too often. The 72-page must-read book, Gun Safety & Cleaning for Dummies, details easy-to-follow instructions in gun safety and training. Top quality cleaning tools include bronze bore brushes, a bore mop, 5mm brass rod, plastic handle, double-ended nylon brush, cleaning patches and a pouch. For use with 9mm/.357 caliber, .40/.45 caliber and .22 caliber guns.
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You dont need to have the fastest hands in the West to see the value in this particular item. Its an easy-to-install magnet that lets you hide a firearm under a desk, shelf or on a door or wall. Great for defending yourself from banditos, highwaymen, gangland enforcers, and probably even a rampaging boar. Holds firearms weighing up to 10 lbs.
Order Over $25 for Free Shipping!
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Use this Gun Mug to give yourself a nice shot of hot coffee! This ceramic, dishwasher-safe mug holds 8 oz. of hot beverage to get you going in the morning.
Hickory dickory dock, this clock could hide a Glock. That's not how the nursery rhyme usually goes, but the world is not Mother Goose, so this unique clock could be the key to a happy ending. It looks and works like a classic mantel clock, but don't be fooled, for this clock also features a hidden storage compartment that lets you conceal valuables, a weapon and more. Clock features a quartz movement and runs on 1 AA battery (included). Overall dimensions are 14 9/16in.W x 4 3/8in.D x 7 7/8in.H.
Keeping your gun clean will give you a better shot. 43-pc. Big Shot gun cleaning kit cleans the majority of all rifles, shotguns and pistols from .17 caliber to 12 gauge. Includes 12-pc. solid brass cleaning jags from .17 to .45 caliber, 6 rods, 2 adapters, 2 plastic slotted ends, cleaning pads, universal handle plus all brushes, mops and fittings. Stores in a replica shotgun shell.
Manufacturer Warranty:
1 month parts / 1 month labor
Your firearms are most reliable, fire more accurately and last the longest when they are clean, oiled and ready to go. This 27-pc. gun cleaning kit works with most shotguns, rifles and pistols to keep them impeccable. This complete set includes 10 wire brushes that fit the following guns: 12-gauge, 20-gauge, 410-gauge, 45 cal. 357/38 cal./9mm, 30 cal., 270 cal, 22 cal. and 17 cal., plus 5 mops to fit 12-gauge, 20-gauge, 410-gauge, 357/38 cal./9mm and 22 cal. Also includes universal handle and adaptors for rifle/pistol rods, 2 solid brass adapter for shotgun mops/brushes and rifle/pistol brush and mops, 2 plastic slotted ends for shotguns and rifles/pistols and 50 cleaning swabs. All stores in a classy aluminum case.
Manufacturer Warranty:
1 year Limited Warranty


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Sending the same ornament to different places? If you order more than one of an item and want them shipped to different addresses, please order them individually. We will ask you for the individual shipping addresses later in the ordering process.
Red Hat Snowman Wood Plaque
Personalized Christmas Plaque
This wood plaque can hang on a door or wall and will bring a smile to your face every time you pass it by. Makes a great winter decoration that isn't just for Christmas.
Material: Wood
and credit card.
Ornaments shown on our site are personalized, as examples only, so you can see where we put the words/names you give us. Some ornaments allow you to select hair or uniform color. If there is no color choice, it is not available on that particular ornament. We will do everything possible to catch any mistakes in spelling, etc., but are not responsible if we do as you request, and it is then not correct. The ornament you see above is the way it will look when you get it, except for the personalizing instructions you give us and any optional attributes you select.
Read what our customers say about our Personalized Christmas Ornaments and their shopping experience!
12/12/2011 - "I received my ornament and my Stand up snowman family, and both of the personalized items were GORGEOUS !!!! I loved them both, and they are way more beautiful then I could ever imagine ! Thank you for doing such a great job, I will definitely be ordering again. Thank You !! Stephanie M. "
11/30/2012 - "We received our ornament yesterday. It looks great. We appreciate how fast we received it, and we plan to order through you again next year. I am also going to tell the ladies at my office about your website. Thanks. Doug G. from Carrollton, Georgia"
10/29/2012 - "Hi Debbie - I just wanted to let you know that I received my shipment this weekend, and everything looks so great. The snowman family with the arrow and due date turned out wonderfully. We really love it. Thank you for all of the extra attention you gave me and this order! Kind regards, Ellen W."


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I would like to believe this is a wmt glitch, but I don't think it is. I only noticed it because someone in another thread asked about a page rank update, so I checked my page rank and found I had gone down a slot after many years at the same ranking. I immediately checked wmt and saw the link issue. Aren't backlinks a large part of page rank? I wonder if others who have lost backlinks in wmt have lost page rank in the past few days.
I then noticed that I had lost a place or two in the search results for various keywords where there is a lot of competition in my niche. I do buy Google ads, precisely because IME, no matter how illogical it might seem, that even if only a small amount is spent, if I buy ads, my rankings are higher than if I don't buy ads. For the links I am losing position on, none of them are keywords with ads associated with them. Coincidence? I wonder. I had planned to start spending on the other keywords in the near future, and now I will notice whether those come up again in the rankings once I start doing that.


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Breaking the Code
Presented by Catalyst Collaborative@MIT at Central Square Theater
April 7-May 8, 2011
Breaking the Code (April 7 – May 8, 2011), Hugh Whitemore's elegant and deeply moving play about brilliant British mathematician Alan Turing, reveals connections between his cracking of the Nazi's "unbreakable" Enigma Code and his refusal to live a closeted life. Turin embraced seeming contradiction: gay man and war hero, marathon runner and Disney film fan; he envisioned a "universal"...
450 Massachusetts Avenue
Cambridge, MA 02139
Admission Info:
$40 for adults, $30 for seniors, $25 for students, and $20 student rush, when available.
General Day and Time Info:
The regular schedule for all performances is Wednesdays and Thursdays at 7:30 PM, Fridays and Saturdays at 8 PM, with matinees on Sundays at 2 PM. There will be no Wednesday evening performance on April 13.
Phone: 866-811-4111
Accessibility Info: Currently, no accessibility information is available for this event.
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Come listen in as Thomas and D-Day get into politics and legal issues ranging from State and US Supreme Court cases to founding documents and IRS and every thing in between that has to do with law.


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Eye Candy: Badass Mushroom Kingdom Art
Because I'm on a deviantART (and mimosa) kick this morning, here comes a wicked-sick (I can say that because I'm cool) picture of the Mushroom Kingdom as envisioned by artist lastscionz. Pretty awesome, huh? I especially like how Yoshi reminds me of the Loch Ness monster because I've always had a crush on that bitch. And how bout that Bowser? Dude looks like Satan himself. If Satan weren't such a pitchfork-toting pussy. High-five, Jesus!
lastscionz's deviantART (with a higher-res shot for your viewing pleasure)
Thanks to P05TMAN and Chaemelion, who have both visited the Mushroom Kingdom before and agree it's a scary place. Especially if you've been eating the Toads.
Denis Medri (of rockabilly/1950's Batman and steampunk Spiderman characters fame) is back at it, this time with the cast of Star Wars reimagined as characters from a 1980's high school movie. He did well. I especially liked Han, Chewie, C-3PO and R2. Oooh -- and Obi Won and ... / Continue →
Remember Star Wars Uncut, the online project in which 473 people recreated 15-second clips from Star Wars: A New Hope with cardboard costumes and/or LEGO and the world's shittiest CGI? Well the project has been completed, and there's a five minute trailer after the jump. And ... / Continue →
Youtube user daneboe, the same guy who created the Contra vs. Duck Hunt and Mortal Kombat vs. Donkey Kong videos is back at it, this time with some Grand Theft Auto vs. Frogger action (and bonus Sonic vs. Pac-Man after the jump!). And, as I've come to expect, they are awesome.... / Continue →


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Bach, Beethoven, & Brahms - with violists Kashkashian & Murrath
Presented by Boston Classical Orchestra at Faneuil Hall Marketplace (Quincy Market)
October 22-October 23, 2011
Beethoven: Wind Octet, op. 103
Bach: Brandenburg Concerto No. 6 (with Kim Kashkashian & Dimitri Murrath)
Brahms: Serenade No. 2
Brahms' gorgeous and symphonic Serenade in A major, with full winds and the warm glow of massed violas, 'cellos, and basses, anchors this program encompassing Baroque, Classical, & Romantic masterpieces. The BCO's winds present Beethoven's late wind octet, and superstar violists...
Faneuil Hall Marketplace (Quincy Market)
4 South Market Building
Boston, MA 02109
Admission Info:
$37-74. Seniors $3 discount, all prices. Students $19
General Day and Time Info:
Oct. 22, 8 pm
Oct. 23, 3 pm
Phone: 617-423-3883
Parking: null
Accessibility Info:
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Richard Strauss 150th Birthday tributePresented by Boston Classical Orchestra at Faneuil Hall March 29-March 30, 2014 |
Flutist Claudi Arimany in MozartPresented by Boston Classical Orchestra at Faneuil Hall April 12-April 13, 2014 |
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7 years in a row. Rated outstanding for quality, satisfaction, service, and on time delivery. 1A Auto selects the highest quality parts from the best manufacturers. Check our excellent ratings.
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Ford Galaxie
Jerry, Pascagoula, MS
Ford Explorer Sport Trac Water Pump & Related
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Some information is missing or invalid below.
Sleep in luxury with this Amy Miller sheet set.
- 4-piece set
- 600-thread count
- Reversible design
What's Included
- Fitted sheet: fits most mattresses up to 14" deep
- Flat sheet
- 2 pillowcases
Construction & Care
- Cotton/polyester
- Machine wash
Promotional offers available online at Kohls.com may vary from those offered in Kohl's stores.
Everything you want to know about sheets is here.
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The TBM 850 is backed by DAHER-SOCATA's extensive worldwide support network that offer services tailored for you. Join the "TBM Family" and you will discover that DAHER-SOCATA is a company that truly cares about its customers and shows in everything we do.
It's all part of being one of the world's leading general aviation manufacturers, with a legacy of over 17,000 aircraft built since 1911 and a reputation for building great products with a support staff that will be there to help you when you need the most.


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February 12, 2012 8:00 PM
Awards offer validation, marketing opportunitiesBy Michelle Muñoz and Daniel Duggan
Related links
Awards for hospitals mean validation. And that validation is a big part of marketing campaigns. In the case of Detroit-based Henry Ford Health System, its "Points of Light" television ad during the Super Bowl touted, among other things, winning the Malcolm Baldrige National Quality Award in 2011. There were only three other winners in the United States. For the University of Michigan Health System, the awards and recognitions generally are used in print and outdoor campaigns, as well as on the system's website, said Dave Brudon, director of marketing. They typically are not used in broadcast campaigns. The importance is the use of a third party, he said. "Anytime a third party, a recognized third party or any of the large groups that do this kind of work, anytime you're recognized by one of those, it's tremendous," Brudon said.
Mike Killian, vice president of marketing at Beaumont Health System, said the recognitions from organizations such as U.S. News and World Report and Thomson Reuters are the result of a hospital doing its job well, not a pursuit of recognition. "We're always delighted to get them," Killian said. "We think in many cases they tell a story that if you add all the information up you get a look at how the hospitals operate." Related Content:
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If you enjoy the content on the Crain's Detroit Business Web site and want to see more, try 8 issues of our print edition risk-free. If you wish to continue, you will receive 44 more issues (for a total of 52 in all), including the annual Book of Lists for just $59. That's over 55% off the cover price. If you decide Crain's is not for you, just write "Cancel" on the invoice, return it and owe nothing. The 8 issues are yours to keep with no further obligation to us. Sign up below.
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Lovely Norman-style stone house on a large estate in Quebec City
- bedrooms 3
- baths 2
- sleeps 8
- pool no
- hot tub no
- pets allowed no
- type House
- community
rates (USD)
/ night
$ 1,500 - $ 2,500 / week
vacation rental description
Lovely Norman-style stone house located on a large estate by the Jacques-Cartier River. Adjoining horse stable. Real paradise for bird, nature and sport lovers.
Services included : Electricity, Internet
Surroundings 1,450,000 sq. ft. estate with private lake and island, paddock, 2 horse-riding training trails, pine forest, hiking trails, salmon river.
Facing the Tantaré Ecological Reserve.jghjh
house rental amenities
Extra furniture : 1 queen-size inflatable mattress
Microwave oven
activities and attractions in Quebec City Quebec
10 min. from Stoneham ski resort
10 min. from the Vacances Valcartier Village.
5 min. from Jacques Cartier excursions
15 min. from Stoneham golf club
10 min. from SAQ (liquor store)-convenience store
15 min. from Stoneham Metro grocery store
15 min. from a health centre and a 24-hr pharmacy
35 min. from Old Québec


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Apple pies with spiced cream
(You can click on ingredients to see more related recipes)
6 | Red apple, peeled and sliced |
1 tbsp | Lemon juice |
⅓ cup | Brown sugar |
½ tsp | Cinnamon |
1 tsp | Vanilla essence/extract |
2 sheets | Short crust pastry |
1 | Egg, lightly beaten |
1 to dust | Demerara sugar |
1 cup | Cream |
- Preheat oven to 200 degC. Place the apples, lemon juice, sugar, cinnamon and vanilla in a large, deep frying pan over low heat.
- Cover and cook, shaking the pan occasionally, for 8 minutes or until just tender. Drain the apples, reserving 2 Tbsp of the juice, and set aside to cool.
- Cut each pastry sheet into 4 squares with a fluted cutter+.
- Top each square with the apples and brush the edges with egg. Fold to enclose, press the edges to seal and brush with the remaining egg.
- Place on a baking tray lined with non-stick baking paper, sprinkle with demerara sugar and bake for 20 minutes or until golden.
- Fold the cooled apple juicemixture through the creamand serve with the pies.
- + A fluted cutter has a scalloped edge. You can also use a knife for straight edges.


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Gear Cutting Experiment with the Taig CNC Milling Machine
By karlw » 1 Comment
Tonight I decided to try cutting a small intricate gear with the Taig CNC milling machine as a proof of concept experiment for another project that I'm working on. The gear is 1-7/8 inches in diameter. I plan on making much smaller gears but the smallest end mill that I have right now is 1/8 of an inch.
It makes a cool necklace. Now I'm ready to rock.
Click through for more info…


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Centre for Restorative Justice (CRJ)
Related sites
The Centre for Restorative Justice (CRJ) is the world leader in experimental and theoretical research on the design and cost-effectiveness of restorative responses to crime. Its mission is to produce, synthesise and apply primary field studies wherever they can be conducted, translating that research into evidence-based policies around the world. The Centre's Director is Dr Heather Strang.
The Centre's global work is focused on the Jerry Lee Program on Randomized Controlled Experiments in Restorative Justice, in affiliation with the Jerry Lee Centre for Experimental Criminology at the University of Cambridge, the Jerry Lee Center for Criminology at the University of Pennsylvania and the United Kingdom-based Justice Research Consortium. The Lee Program is co-directed by Dr Strang and Lawrence Sherman, Wolfson Professor of Criminology at the University of Cambridge.
Data consultant
Additional data expertise on the Centre's projects is provided by:
Mr Malcolm Mearns (MA Hons) Datacol Research Pty Ltd PO Box 170, Civic Square, ACT 2608 Email: email@example.com
The work of the Centre has been financially supported by:
Australia Research Council 2006-2010
Australian National University
Barrow-Cadbury 2003-2005
Canada Council
Criminology Research Council
Esmee Fairbairn Foundation 2003-2005
Federal Office of Road Safety (Commonwealth Department of Transport and Regional Services)
Jerry Lee Foundation
National Drug Crime Prevention Fund (Commonwealth Department of Health and The National Police Research Unit)
Smith Institute 2006-2007
Updated: 14 January, 2013/Responsible Officer: Director, Regulatory Institutions Network/Page Contact: Director, Regulatory Institutions Network


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Welcome to Breezy Hill Orchard and Cider Mill's home on the web. To keep informed of the latest news and events please email us to be added to our email list.
The 2013 Wassail is on May 18
Click here for more info
Or you can browse our recipe section, for mouth watering apple dishes. Also be sure to check out our photo gallery for a tour of the farm.
I Contact Us I Thanksgiving Pie Orders I About Us I Recipes I Directions I Photo Gallery I Stone Ridge Orchard I Knoll Krest Farm I


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Magic Speed
Your PC is slow in boot-up and running? Magic Speed will make your PC faster and more efficient in 5 simple steps. The software package includes startup management, fixing registry errors, Disk clean-up, and memory management. It does not require special PC knowledge!
Magic Speed will analyze your applications, which are loaded with your PC boot-up. Are you sure that you really need these applications? When loaded, they occupy PC memory and slow down PC operation. A check-up will also include virus and spyware tests thanks to a new anti-virus engine updated on a daily basis.
Registry errors also negatively affect PC efficiency. By deleting temporary files, you will increase free space on your hard drive and speed up its operation. Make use of the unique Boost Windows option - by adding it to the startup you will discover a great improvement to your PC operation!
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Smart PC Magic Speed News
13 Jul
How To Download Registry Cleaner Software by Christian_Doerr
A registry cleaner has many benefits for the system and a clean registry is vital for a stable computer system. However there is a debate whether user get the best registry cleaner for money or if a free registry cleaner is better. But… Read more on Download Registry Cleaner
12 Jun
What Will Make My Computer Faster?
A faster computer is a more efficient computer. No matter if you use your PC for personal or business use, you don't want to be slowed down along the way. Fortunately, there are things you can do to speed up your computer. … Read more on Make My Computer Faster
5 Jun
How Can I Speed Up My Computer For Free?
Is your computer running slow? If so, you know just how big of a deal this can be. Not only does it hold you back from completing your day to day tasks, but it may also mean that something is wrong. There are several things you can do… Read more on Speed Up My Computer For Free
1 Jun
A Guide To Easy Slow Computer Solutions by ABradney-George
Even the most basic tasks can become a struggle when dealing with a slow computer, and finding a solution can be just as hard. A lot of time could be spent trying to find out what is causing the problem, but in many cases there is more… Read more on Slow Computer Solutions
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Five Steps For A Faster Computer
Most experienced computer users know there is a need for keeping their computers running clean, lean, and mean. But why and how their units have slowed down might not be known. Here are five steps take to help speed up your PC: Try to… Read more on Faster Computer
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Frozen Imps – Physics Based Puzzle Game
Frozen Imps is a nice physics based puzzle game by BestPhysics.com
Object of Frozen Imps is to shoot at all the blocks to remove them and make the frozen imps fall into the fire.
There are 28 challenging levels for you to unfreeze. Happy Puzzling!
Tags: Puzzle Game
Category: All Puzzles, Physics-Based Puzzlers


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Rede CEDROS
Site in Portuguese. DROS é um acrônimo em português que significa Rede para Cooperação em Estudos e Desenvolvimento de Recursos Odontológico para o Setor Saúde. A Rede é composta por…
CT Suite
A modest collection of field recordings, recorded interviews, transcripts, and photos—research materials for my book CT Suite: The Work of Diagnosis in the Age of the Mechanical Viewbox (Duke Univ. Press, forthcoming fall 2008). This is a…
Bangladesh Association for Prevention of Septic Abortion
The cardinal mission of BAPSA is to improve the reproductive health care services through a community based social development approach. In this respect, the organization seeks to create an environment that would guarantee an improvement in the…
Pediatric Rheumatology casebook at the University of North Carolina at Chapel HIll
Pediatric Rheumatology casebook
QUANTITATIVE ANALYSIS OF Hg, Ag, Sn, Cu, Zn AND TRACE ELEMENTS IN AMALGAM REMOVED FROM AN ABUTMENT TOOTH
The author decided to have a sample of amalgam tested after a gold alloy bridge that had been in vivo for 9+ years came loose and fell out of his mouth.
Welcome to the Prostate Cancer Coalition of North Carolina (PCCNC)
The Prostate Cancer Coalition of North Carolina is a community of people dedicated to the defeat of prostate cancer. By working together the citizens of North Carolina will see a day when prostate cancer is no longer a threat to the families of our…
NEC New Voices Project
This collection is for research conducted jointly by the UNC Center for Disability and Literacy Studies ( http://www.med.unc.edu/ahs/clds/ ) and the UNC Department of Computer Science.
Pratyasha: Cancer Children's Welfare Society
'Pratyasha' (which means 'Hope' in Malayalam) is a support group for children with cancer - a helping hand for families of children and young people with cancer. 'Pratyasha' was formed in April 2003 under the aegis of…
Section 27 and Public Domain Books Page
The Section 27 and Public Domain Books Project houses digitisations (primarily in the form of scans) of books covered by Section 27(1) of New Zealand's Copyright Act 1994 -- that is, many Kiwi court, inquiry, municipal and parliamentary…
The PRIME II Project
The PRIME II Project was a partnership combining leading global health care organizations dedicated to improving the quality and accessibility of family planning and reproductive health care services throughout the world. Funded by the United States…


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Wednesday, March 12, 2014
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After being in business for more than 75 years, a Rochester diner closed its doors for good on Wednesday. Al's Stand, a fixture in northwest Rochester since 1936, has served its final customer. YNN's Mike Hedeen caught up with some regulars during the restaurant's last lunch hour.
ROCHESTER, N.Y. -- There was a large crowd for lunch at Al's Stand Wednesday. Since it was the last day of business for the local diner, there was no guarantee that all customers would be served.
"The plan today is to cook until we're out of food but stay open for anybody that wants to come down and just say goodbye to Al's," said Joe Lucchese, Al's Stand.
For more than 75 years, Al's has been a fixture in the area around Jefferson High School. But those running the restaurant say it's been difficult to keep it going.
"I have a lawsuit with a family member… We've been fighting a battle for a couple of years now and I just can't continue to fight the battle," said Lucchese.
According to a family attorney, the lawsuit is over who is the rightful owner of the restaurant.
Back in the day, Al's was a hangout for Jefferson High School students. Many of them would come there during their lunch hour. And they were back on the final day of business remembering those good old days.
Like Frank and Guane Umbrino. They were back for one last time, sitting in the same booth where they met and became high school sweethearts and then husband and wife.
"I looked at her and said 'that's the girl I'm going to marry' and that's true. And I did, 44 years ago," said Frank Umbrino, an Al's customer.
"And 44 years, we're still together," said Guane Umbrino.
They've been regulars ever since the day they met and have fond memories of Al's.
"The good times, the friends, it's not the same," said Guane.
Most customers had similar feelings, saying they're glad they were able to pay one final visit.
"Really sad, but it was a fun place to come to when we were in high school, a fun place. We'd listen to the music, no arguing or fighting. Then we'd go back to class and our studying then come over after school for Cokes," said Mary Ellen Martin, an Al's customer.
"I feel horrible. I feel like I'm letting all these people that are here down," said Lucchese.
Weather alert » More alerts
From the Weather On The Ones Forecast Center, The National Weather Service Has Issued A BLIZZARD WARNING for the following counties: Genesee, Niagara, Orleans -- expires Thursday at 2:00AM. BLIZZARD WARNING for the following counties: Cayuga (North), Livingston, Monroe, Ontario, Wayne -- expires Thursday at 5:00AM. WINTER STORM WARNING for the following counties: Wyoming, Allegany -- expires Thursday at 2:00AM. WINTER STORM WARNING for the following counties: Cayuga (South), Schuyler, Seneca, Steuben, Yates -- expires Thursday at 8:00AM.


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Gifts for Mom for Teens - Personalized Gifts
Gift Buzz
When shopping for teen guys, it's essential to know the difference between awesome and dorky. Our Gift Gurus are trained to track such differences so that your fave male teen will think both you and your gift are, 'totally cool.' Start shopping... Read More »
Personalized gifts are one of the hottest trends this holiday season. Adding someone's name, initials or a special message is both timeless and totally on-trend. Ready to pick your perfect personalized gift? Check out our unique, thoughtful... Read More »
When we think of Mother's Day we think of sending bouquets or jewelry, but what about something more personal? Show her you care by giving her a personalized Mother's Day gift that she'll actually love using. Here we go...I'm going out... Read More »
All fall, people have been asking me one question: "What are the hottest gifts for the holidays?" I've been telling them the trends I'm seeing, including Uggs, succulents, tablet computers, and a whole category of gifts: personalized gifts.... Read More »


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Personal project based on the movie "3:10 to Yuma".
To add items to your wishlist, simply click the "Add to Wishlist" link from any product page.
by Victor Beuren
Collect your choice of gallery quality Giclée, or fine art prints custom trimmed by hand in a variety of sizes with a white border for framing.
IllustrationVintageMovies & TVGraphic Design


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Mar 14Rep. Mike Quigley's Transparency in Government Act would give the public greater access to information on lobbying, lawmakers' personal financial reports, filings by tax-exempt nonprofits and more.Continue Reading »
Mar 13We're hosting a mini-conference on roadblocks to transparency in the U.S. government -- and proposing some solutions. Experts from CRP, Campaign Legal Center, Covington & Burling, Center for Public Integrity, CQ Roll Call and more will address the issues in panels on campaign finance, lobbying, and the growth of dark money. Sign up now! Continue Reading »
Mar 12Rep. Eric Cantor's leadership PAC has spent more than $170,000 on restaurants in the 2014 election, nearly 12 percent of the PAC's total nonpolitical expenditures; that outstrips, both in dollars and as a percentage, what's being spent on eateries by other high-ranking House members. Continue Reading »
Just as water flows downhill, money in politics flows to where the power is. And the Center for Responsive Politics is there to help you follow the contours and learn about these connections.
Patriot Majority USA
AGAINST: Cotton, Tom |
$149,665 |
Mississippi Conservatives
AGAINST: McDaniel, Chris |
$58,355 |
Patriot Majority USA
AGAINST: Cotton, Tom |
$57,500 |
Freedomworks for America
FOR: Bevin, Matt |
$24,990 |
Special Operations for America
FOR: Cotton, Tom |
$15,000 |


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Home > Member Center > Career Center > Career Center
To list a career opportunity, please email a brief job description to Executive Director Katherine S. Bifaro at email@example.com. The information will remain on our site for four weeks unless otherwise requested. Vacancies will also be included in an e-newsletter sent to members.
Health law attorney
Hodgson Russ LLP is seeking a highly qualified attorney for the Health Law practice group in our Buffalo or Albany office. The practice group counsels hospitals, nursing homes, home health agencies, clinics, ambulatory surgery centers, behavioral health providers, disability service providers and licensed professionals and represents many non-profit, public, and for-profit health care organizations, including some of the largest hospital systems in New York State.
The successful candidate must have at least six years of relevant experience dealing with federal and New York State health law issues (such as fraud and abuse, practitioner referral and tax exemption issues); regulatory compliance and transactional matters; preparation, review and negotiation of contracts and corporate documents; and issues relating to professional practices and licensing. Stellar academic credentials and excellent written and verbal communication skills also required. Experience in administrative proceedings or reimbursement/compliance issues for health systems, hospitals, long term care providers, managed care organizations, or medical groups is a plus.
Please send resumes and cover letter to Shannon Scott, Attorney Recruiting Coordinator at email@example.com.
Assistant United States Attorney vacancies
Tax Attorney (Syracuse)
Hiscock & Barclay, LLP, a 210-attorney law firm with 30 practice offerings and ten offices throughout New York State and the Northeast, is seeking to hire as part of the firm's expanding Tax Practice a highly motivated associate with 1-5 years of experience.
Candidate must have excellent writing, research and communication skills and strong academic credentials from a nationally recognized law school. Applicants with an LL.M. in Taxation and admitted to practice in New York State are preferred.
Practice Description:
Hiscock & Barclay's tax attorneys work with businesses of all sizes in a wide variety of industries to develop plans that maximize their earnings while minimizing their tax exposure. Our attorneys' knowledge of federal, state and local taxation allows us to customize tax plans that permit our clients to achieve their personal and business goals with the least onerous tax consequences.
We also provide advice and guidance to attorneys throughout the firm who need to understand the tax consequences of client business transactions. This firm-wide teamwork ensures that our clients receive the most thorough analysis and the best possible solutions to their business problems.
Our attorneys work in all areas of federal and state taxation, including corporate income and franchise tax, mergers and acquisitions, information reporting compliance, employee compensation, benefits and retirement plans, partnerships, trusts, and other conduit entity taxation, municipal finance, sales and use tax, and corporate tax planning, including Subchapter S planning. We also are able to provide guidance involving matters of individual income taxation and complex estate and gift tax planning.
Qualified applicants should submit a cover letter, resume, law school transcripts, and LLM transcripts (if applicable) in confidence to:
Hiscock & Barclay, LLP
Recruitment Coordinator
One Park Place
300 South State Street
Syracuse, NY 13202
Contact: Vanessa Campbell
Phone: 315.425.2721
Fax: 315.703.6266
Email: firstname.lastname@example.com
Location: Syracuse
Associate Attorneys
Hamberger & Weiss is seeking applicants for full-time associate attorney positions in its Buffalo and Rochester offices. Applicants with experience in workers' compensation matters are preferred. Admitted attorneys should forward a cover letter indicating the preferred office for placement, resume, writing sample and transcript to the attention of Mr. Daniel Bowers at dbowers@ hwcomp.com.
Support Magistrate - erie county family court
Deadline: March 7, 2014
General Counsel
Tara Cares, a company providing support services to nursing homes in several states, is seeking an exceptional candidate to fill the position of General Counsel at our Orchard Park, NY office. In addition to providing advice on resident care issues, the General Counsel will attend trials, arbitrations and mediations to resolve cases, and assist outside counsel with litigation strategies and witness preparation. Requires a degree from an accredited law school with a current license to practice and 7-10 years of legal experience, including experience with a major law firm, personal injury, medical malpractice, corporate law, litigation, and courtroom experience.
For more information, or to apply for this position, please visit: http://taracares.iapplicants.com/ViewJob-521269.html
Consumer Lending Senior Counsel
First Niagara Financial Group is seeking an attorney to join the Legal Department in Amherst, NY to provide legal counsel on consumer lending issues with a primary focus on open- end and closed- end consumer loan products and services, including credit card lending. In addition, the position includes providing legal advice to the business line on consumer lending product development, operations, servicing and collections and working with the Compliance Department to review and analyze regulatory developments impacting consumer lending. A Juris Doctorate from an accredited law school, admission to the New York, PA or CT State Bar and a minimum of 5 years of legal experience combining corporate legal and private law settings including significant experience with matters pertaining to residential lending and loan servicing or consumer finance law are required. The ideal candidate will have a strong working knowledge of applicable federal and state banking regulations including Truth in Lending, Equal Credit Opportunity Act, Fair Credit Reporting Act, RESPA and HMDA, excellent business judgment and ability to apply business solutions to legal problems and experience working with all levels of business units, outside counsel, regulators, and compliance. Please submit resume, cover letter and salary requirements by applying online at https://www.firstniagara.com/About_Us/Careers/Careers.aspx, position posting # 14-10415.
Seeking Associate Attorney Positions
Hamberger & Weiss is seeking applicants for full-time associate attorney positions in its Buffalo and Rochester offices. Applicants with experience in workers' compensation matters are preferred. Admitted attorneys should forward a cover letter indicating the preferred office for placement, resume, writing sample and transcript to the attention of Mr. Daniel Bowers at dbowers@ hwcomp.com.
Project Attorney
Experienced Civil Litigation Attorney available for project work, briefs, motions, depositions or other assignments. Will accept payment by the hour or by the project. Please contact firstname.lastname@example.com for further information.


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2 people found this helpful
I worked at Cambridge Associates, LLC full-time
Pros – I enjoyed working with my coworkers in the "secluded" office. They were about the only thing that kept me at Cambridge Associates.
Cons – Lack of experienced management, communication, and help. When you speak up, no one ever listens or tries to fix the situation.
Advice to Senior Management – Listen to your employees when they speak up to you. We are speaking up for a reason.
No, I would not recommend this company to a friend
I have been working at Cambridge Associates, LLC full-time for more than a year
I worked at Cambridge Associates, LLC full-time for more than a year
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Sponsored Links:
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Wendy Knowler fights for your rights...
Strange how the supposedly random allocation of cases shapes a judge's public reputation. I'm thinking here in particular of Judge Mahomed Navsa of the Supreme Court of Appeal, but there are others in a similar position.
After sitting in several high-profile controversial cases and writing the judgment in those cases, Judge Navsa has taken considerable flak over the past few years.
Among the decisions he has written – with the unanimous agreement of the four appeal court colleagues who heard the cases with him – was the judgment on whether the decision to drop corruption charges against President Jacob Zuma could be revisited by the courts.
Another examined whether the appointment by Zuma of Menzi Simelane as national director of public prosecutions was constitutional.
In both, his theme was that no one was above the law and that even the head of government had to act constitutionally.
Typical of Judge Navsa's writing in these decisions is the following: "No one is above the law and everyone is subject to the constitution and the law.
"The legislative and executive arms of government are bound by legal prescripts.
"Accountability, responsiveness and openness are constitutional watchwords. It can rightly be said that the individuals (who) occupy positions in organs of state or who are part of constitutional institutions are transient but that constitutional mechanisms, institutions and values endure.
"To ensure a functional, accountable constitutional democracy the drafters of our constitution placed limits on the exercise of power. Institutions and office-bearers must work within the law and must be accountable.
"Put simply, ours is a government of laws and not of men or women."
These are important observations, and ones the public should agree with wholeheartedly; if it were otherwise we would all have a far tougher life with no one, not even the courts, ready to call the government to account when it overstepped the mark and acted unlawfully. But Judge Navsa and his colleagues do not always find themselves in conflict with the government.
This happens only when the executive and its bureaucracy are found to have acted outside the constitution. Sometimes – at the end of the appeal court's most recent term, for example – the court not only agrees with the approach of the government but compliments it on work well done. You may find this difficult to believe, since the government has been trying to create a sense that the courts are at war with the elected representatives of the people. But it happened most recently in a pair of judgments delivered in late March.
The two decisions concerned government arrangements to ensure that the fishing industry was conducted in a way that achieved two main aims: first, sustainability, with the resources off our coasts being managed in a way that ensured they were not overfished; and second, the transformation of the industry itself. In the two cases, companies involved in the fishing industry challenged aspects of government policy.
One issue was the fact that after fishing permits were granted parties had to inform the government of any changes to the company's structure and ownership affecting the level of transformation.
The companies complained about these conditions and said they were vague, illogical and should be set aside. One of these companies had restructured, bringing in a new major shareholder from the UK and significantly reducing black shareholding.
At the time the permit was granted, it was 59.35 percent. Depending on whose version you accepted, it was 19.364 percent or 21.59 percent after restructuring.
"On either basis the effect on transformation is stark," said the court. The companies involved claimed that they had gone to court to ensure "responsible and progressive transformation", noted the court, but this was "belied by their actions" in making this deal. In the end the court not only found the policy lawful and reasonable, but went further, complimenting the department for the way it carried out its work in achieving these two aims.
Here's a key passage from the decision: "In our constitutional order courts have fulfilled their constitutional duty when the legislature or members of the executive transgressed the bounds of the power vested in them and have made the necessary orders.
"In instances such as the present, when members of the executive fulfil their constitutional duties and meet the constitutional transformation imperative in impressive fashion, courts should say so."
And the author of this praise? Writing for a unanimous court, none other than that allegedly fierce enemy of the government, Judge Navsa.
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Monday, April 14, 2008
Mid Morning
Thompson was very bullish very late and candidly I can't recall anything he has ever said opinion-wise (as opposed to giving data from analysts they survey which has some utility) having much value or being right very often. If you know something different please leave a comment.
It is possible this is just some sort of show because he is often strangely upbeat, now today he was whiny. Maybe he really feels the emotions he displays. Whatever the reality (a show or the real thing) I don't think it is anyway for an analyst to act and potentially elicits an emotional response on the part of some investors which does a true disservice.
I have no idea what his background and experience is (presuming it is pretty good) but just as leaves fall of the trees in autumn, bull markets give way to bears at some point.
Hopefully you can see the forest for this sort of tree and know to discount the credibility of an emotional response from someone who is supposed to be a professional.
13 comments:
- McCan said...
Reminiscent of rosy reports by BS (and others) regarding their solvency, just prior to their collapse. This was a popular occurrence before the tech crash. Picture Kevin Bacon screaming, "All is well" at the panicking hordes during the closing moments of Animal House. The next thing you know a pirate is driving off in someone else's convertible with an underwear-clad cheerleader.
Broadcasters are in the business of contributing to the corporate bottom line via advertising sales. They sell advertising to big corporations. Giving a rip about whether you and I get skinned and hung out to dry does not enter into today's broadcaster menu of concerns. At the top of the list is today's share price.
Time to go find my sword and eye patch... - 9:04 AM
- Roy said...
I'm not sure that was Michael Thompson (video of the interview is up on the CNBC site, btw) - looked more like Irwin Mainway, lol!
- Roger Nusbaum said...
the Dan Akroyd character?
- Anonymous said...
If I were to believe Zillow.com the houses in my neighborhood are off 20 to 25% from the peak (FL).
Case Shiller if memory serves correctly has tampa and miami at 18 to 19% off the peak based on January data.
I do not know how recent zillow data is but these seem relatively close to me. Housing seems to continue falling. I expect to see a lot more whining and complaining and blaming to be done.
One comment I read I know I have posted here is that this will turn out to be a slow motion train wreck. I am beginning to see the accuracy and clarity of whoever made that statement.
I would like to also point out the trillion dollar problem has gone from a crazy, outlandish projection to an acceptable estimate by many for the problems we face.
It continues to look like we are turning Japanese, but this time a bunch of other countries will be following down the same path.
On a positive note while housing is horrible here from what I have read the housing bubble in the US on average never got as bad as it did in Japan. So maybe we end up with a Japan lite? I do not know, but I still think this will be worse than your average recession. I am also sure there will be strong rallies along the way which will make my comments look stupid as well, but I would not bet the farm on those rallies.
- Roy said...
Roger, I mis-typed - Nathan Thurm is the SNL character that came to mind when I watched that!
SEG - Zillow's got our house off 14% (San Jose), but there hasn't been a comp since 10/7/07 and that house was off 7% - about right, based on its condition, IMO. We used Zillow to buy this house, but at the time there were 6-8 recent comps. - 11:46 AM
- Anonymous said...
I do not trust Zillow for my house or any one specific house. I do trust zillow averages for a neighborhood, which takes more work to evaluate. The comp $/sqft seems ok.
My house IMO use to be 5 to 10% under priced and now it seems 10% over priced on zillow. Remember it is a zestimate as they say.
seg - 11:59 AM
- Anonymous said...
Hussman is a must read this week IMO.
Third inning - 12:48 PM
- RW said...
I can definitely see the possibility of an extremely serious recession but still see evidence there are very large quantities of eurodollars stashed in other countries that must eventually be repatriated so I continue to think the main probability remains a mucky mush, a bear that is relatively 'normal' in depth but with poorly defined edges, maybe a 'W' or 'WW' (double-dubya) in honor of the dude from Crawford or, if we are somewhat less fortunate, an 'L'
Ordinarily I'd make a stronger distinction between the economy and the equity or debt markets but financial institutions play such a central role in the credit-based economy we are becoming (or have become) I'm not sure how realistic that is any more. - 12:51 PM
- Anonymous said...
From an article on CNNMoney - The best investment in 10 years: Get in while you can.
They have a best-of-class ETF portfolio. I was wondering what you thought?
These five ETFs stand out for their rock-bottom fees and strong records in tracking broad-market indexes. You can put together a simple yet fully diversified portfolio just by spreading your money among all five.
Unfortunatley I can't copy-paste their table.
Vanguard Total Stock Market (VTI) - 30%
Vanguard REIT (VNQ) - 10%
Vanguard FTSE All-World ex-U.S. (VEU) - 20%
Vanguard Total Bond Market (BND) - 30%
iShares Lehman TIPS Bond (TIP) - 10% - 4:33 PM
- Roger Nusbaum said...
no small cap (effect), REITs seemed to have a high correlation to financials when things hit the fan, no emerging markets (effect), no commodities, no meaningful foreign fixed income.
- Stephen Drone said...
Yeah, that's the usual generic ETF portfolio.
Small caps are, what, 1.5% of the total portfolio. Emerging markets are even less than that. - 6:11 PM
- Stephen Drone said...
Interesting. I checked out the article.
The "Fix your mix" calculator thing is a redux of an article they did months ago (some time last year, I think) on setting up portfolios for people in different "life places." - 6:15 PM
- Rick said...
For Roy (with house in SJ)
I've seen wild discrepancies between the different sectors in greater San Jose. Los Gatos/Saratoga is holding firm, while some of east SJ is bid-free.
Follow the tech employment. If that falters, there could be something of a rush of foreclosures. (I grew up in SJ area and am stunned by the prices (still) attached to some very unspectacular ranch tract homes built in the early '60s.) The potential for a meaningful correction (25%) is very high, IMO.
R in NY - 8:58 PM


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Part of a national program started by a real estate company in Minnesota in early 2002 to recognize community heroes, Patton Property Group CEO Rowena Patton said she decided to bring the national program to the area as a means of giving back to the community. "It's a small way to give back...but it's about $1,500 on a $200,000 home, so it's considerable," she adds.
Casting a wide occupational net, the Homes for Heroes discount is actually available to a majority of Asheville residents according to Patton. "It's about 70 percent of the population here," she reveals.
"I think it's the kind of grassroots thing that, when you get a couple of doctors standing there with their big checks at the closing, then they'll start telling their friends, and it'll start rolling," says Patton noting that, though Asheville Home for Heroes started just three weeks ago, they're already seeing results, with around seven people (both home buyers and sellers) signed on for the program.
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TBK brand Icing Shortening Is What Many Professional Bakeries Use In Their Buttercream Icing. Even In warm weather, buttercream icings will have body and stability when made with TBK Icing Shortening. Store bought all-purpose shortening doesn't have the same stabilizers, so your cake icing will break down and appear grainy. TBK High Ratio Icing Shortening is the true brand of high ratio shortening. Here's a great recipe:
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Ingredients: Partially Hydrogenated Vegetable Oil (Soybean and Palm Oils), Mono-diglyceridis and Polysorbate 60


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31 May 2001
Division of labor takes center stage
by Bob Felton
Hooking up is increasingly necessary to get the job done.
"How many people," economics professors like to ask, "does it take to make a pencil?" The correct answer-one that emphasizes the complex relationships that tie together miners, loggers, transporters, manufacturers, distributors, and retailers-is "too many to count." Though division of labor and cooperative action are inherent in capitalism, there is something new afoot when job titles such as "Apostle of Partners" begin appearing on business cards. Separating the new from the gussied-up commonplace can be difficult, however.
Adorning the ordinary
The decade-long shift away from vertically integrated colossi toward flat, fleet-footed businesses that do just one or two things well, plus the corresponding business restructurings and layoffs, in most cases doesn't mean jobs have truly disappeared; they are, instead, performed someplace else by a different firm, or "outsourced." Widgets International might get rid of its truck fleet, for instance, but the company continues to pay somebody to move goods between its manufacturing plants and distributors' stores. If the company's by-the-hour flacks are up to the minute, they announce that the company has formed an alliance or partnership "an association or union formed for the furtherance of the common interests and aims of the members," according to Webster's dictionary to get the job done instead of merely hiring a trucking firm. Behind the weighty descriptors and buzzword-laden press release is a straightforward, work-for-pay transaction as old as the wheel.
One-way alliances such as these are often short lived. If the trucking company can't keep its commitments, the manufacturer simply hires a trucker who can. Other business relationships are more complicated, though.
Something old, something new
A second sort of partnership that's attracted a lot of interest in the past few years is the electronic exchange, the modern e-equivalent of the ancient bazaars. Covisint, an automaker-owned exchange, is the premier example. Participants go online to seek price quotes, conduct or participate in auctions, and collaboratively design automobile components all the transactions that go into making a car. Because the exchange is owned by the automakers and gets a piece of each transaction, the automakers are collaborating as real partners to profit from an activity that ought to lower their actual costs or at least mitigate the rate of cost increases.
They do this to be competitive so that their dealers can beat one another silly in price wars.
These cooperative arrangements cut costs and increase competition, and companies that don't participate in the exchange and don't use the efficiencies of e-commerce will lose when they put their products in front of consumers. Practically, the automakers have entered a marriage of convenience that Ray Noorda, onetime Novell chief executive officer, liked to call "coopetition." Ideally, it's a relationship where all participants benefit because their joint efforts help the market grow.
Nightmare scenario
More than a decade ago, fearing his company was losing its competitive edge, AutoDesk founder John Walker wrote a memo that subsequently became known throughout the software industry as The Nightmare Scenario. "Damn," Walker imagined Bill Gates muttering to himself, "what I need is more money." Gates would then focus on the computer-aided design (CAD) market with cyclopean intensity, Walker figured, and run Walker's measly $200 million software company right out of town.
Inexplicably, Gates never developed a hankering to rule the CAD world, and Walker got to keep his money and move to Switzerland. But Windows operating systems (OSs), which control everything from huge networks to pocket computers, open Internet communication standards, and the subsequent tendency toward commoditization of measurement and control instrumentation, have combined to put tremendous pressure on instrument makers and software developers to find ways to distinguish themselves and win customer loyalty. Increasingly, firms are teaming with others possessing complementary technology to jointly develop and market products. These are real partnerships or alliances, according to the accepted meaning of the words: Each company relies on the other in order to achieve their goals.
Among the most successful is VenturCom's partnership with Microsoft, a relationship that is setting the direction for automation in locales ranging from construction sites to plant floors to Los Angeles streets. Microsoft's Partner of the Year in 2000, VenturCom developed the version of Windows NT put on microchips (NTE) and embedded into intelligent devices. Essentially, devices become another node on a Windows NT network, eliminating the need for an intermediary that translates between Windows NT's native command set and the native language of a remote device. Further, VenturCom has developed additional capability for NTE that supports real-time control of devices, RTX Version 5.0. The result is that devices communicate directly with back-office applications, avoiding layers of intermediate software products. Further, Windows applications and there are zillions of Windows programmers around may be used to schedule and control the devices.
VenturCom announced in February, for instance, that Cleveland Motion Controls is using NTE and RTX in a new shape-cutting control system. The NT platform allows the cutter to talk with business applications and additionally makes preemptive scheduling and the full computing power of the OS available to the application controlling the cutter. Cleveland offers its clients a product that is integrated with standard accounting and inventory packages and controllable using a clock and mathematical algorithms of any sophistication.
VenturCom has found other folk to use the NTE/RTX combo, too. SK Group of Nice, France, has integrated it into a new line of cranes used in construction. Sensors mounted to the boom continuously monitor the location of other cranes and construction equipment, and the underlying software application automatically seizes control of the machinery, coordinating with other devices on the network if a collision appears likely. Operators communicate and control equipment using a familiar OS that requires no special training.
A partnership comprised of VenturCom and VersaLogic will develop a rudder control system for use on the U.S. Navy's destroyers, under contract to Litton Marine Systems. Pacific Current Information Systems developed a NTE/RTX-based fruit packing system that sorts, diverts, packs, and weighs cherries, then prints the shipping labels. In Los Angeles, sensors embedded in roadway pavement send traffic data back to City Hall, where traffic-light timing is automatically updated to keep traffic moving smoothly.
AutoDesk may have slipped under Gates' radar, but it's clear that Windows OSs, supported by applications such as SQL Server, are going to become increasingly important on the plant floor as information technology departments learn there's a way to sidestep the bewildering complexity of multiple control and reporting applications, implementing multiple communications protocols from multiple vendors. Microsoft's partnerships with firms such as VenturCom and Iconics, whose president, Ross Agrusa, described his company's products as "Microsoft to the core" at an ISA EXPO/2000 press conference, could provide the breadth of capability that lets Microsoft finally become dominant enterprisewide and dislodge enterprise resource planning and manufacturing execution systems developers outright.
Product placement deals
Ever since ET scarfed down some Reese's Pieces and sent Hershey's profits into orbit, marketing types have regarded product placement deals with something akin to reverence. Thanks to plant simulation and design software, manufacturers of monitoring and control instruments have a new way to get their products in front of potential purchasers. An 8 March press release headlined "Fisher-Rosemount and Hyprotech form alliance to deliver integrated process control solutions" exemplifies these arrangements.
Engineers have been using design and simulation software for years. What has changed is that it's no longer necessary to use generic "black box" devices in their analyses. Now, designers open an e-catalog to select a part, and the analysis uses its properties automatically. Not only are the analyses and simulations more accurate than when using a generic pump, but also when the designer is satisfied, he gets a list of part numbers ready to send to purchasing.
The Hyprotech software doesn't limit designers to using only Fisher-Rosemount equipment, but it gives Fisher-Rosemount an edge with users of Hyprotech's design package. Hyprotech will provide data from other manufacturers sometime in the future, but until that happens, plant engineers could still find themselves thumbing through thick catalogs and calling local sales reps for engineering data and current prices.
On the other hand, Intergraph, developer of the SmartPlant PID and InTools packages, favors an open design that allows any manufacturer to connect to its software, relying on manufacturers to develop and maintain engineering properties databases. IT
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Appointment | |
Appointment type: | Receivership |
Appointment date: | 14 April 2010 |
Appointee(s): | Tim Norman and Sal Algeri |
Office: | Melbourne |
Enquiries: |
Investor and creditor enquiries
URL: | http://www.deloitte.com/au/forest_enterprises |
FEA is an ASX-listed forestry and forest products company formed in 1985 that operates across the timber processing and agribusiness industries.
Deloitte partners Tim Norman and Sal Algeri have been appointed as Receivers and Managers of Forest Enterprises Australia Limited (FEA) (ASX Code: (FEA)) and wholly owned subsidiary FEA Carbon Pty Ltd (FEAC) on 14 April 2010.
Mr Norman and Mr Algeri have also been appointed as 'agents for the mortgagee in possession' of Tasmanian Plantations Pty Ltd (TP), another wholly owned property holding subsidiary of FEA all on 14 April 2010.
FEA Plantations Limited (FEAP) entered voluntary administration on 14 April 2010 and is controlled by BRI Ferrier. FEAP is a 100% owned subsidiary of FEA and is the responsible entity for the 17 forestry Managed Investment Schemes (MIS).
Section 445F Meetings of Creditors for Forest Enterprises Australia Limited (Receivers and Managers Appointed) (Subject to Deed of Company Arrangement) and FEA Plantations Limited (Receivers Appointed) (Subject to Deed of Company Arrangement) to be held on Friday 28 June 2013.
S.445F Report to Growers 18 June 2013 |
FEA – proposed Varied Deed of Company Arrangement June 2013 |
FEAP - proposed Varied Deed of Company Arrangement June 2013 |
FEA Letter to growers generally – 1995 to 2009 30 September 2011 |
Court application - Declarations Proceeding - commenced September 2011
Mr Norman and Mr Algeri, as Receivers and Managers of FEA and FEAC (and controllers of TP) have brought a proceeding in the Supreme Court of Victoria (the Declarations Proceeding) in order to seek declarations that any head leases, forestry rights, Grower Leases or other interests granted in respect of land that is owned by TP, FEA or FEAC are at an end, and that the Receivers and Managers are able to sell the land unencumbered by those interests.
FEAP, in the hands of its Deed Administrators, is a defendant in the proceeding and is opposing those declarations.
The Declarations Proceeding will affect the interests of Growers who have an interest in any Scheme in respect of land that is owned by Tasmanian Plantation, FEA or FEA Carbon. Two representative defendants, who are Growers themselves, have been joined to the proceeding in order to represent the interests of Growers.
On 9 November 2012, the Court ordered the Receivers and Managers and FEAP to take steps to publish a Notice to Growers in relation to the Declarations Proceeding and the appointment of the representative defendants.
The Notice to Growers is an important document for Growers. It contains information for Growers about the issues in the Declarations Proceeding, how it will affect their interests, steps that they might wish to take prior to 14 December 2012 and how they may contact either the representative defendants or the Court in relation to the Declarations Proceeding.
Links to the Notice to Growers and to the key court documents from the Declarations Proceeding are provided below. Before accessing those links, you must read the statement below. Accessing those links indicates your acceptance of the following statement:
You must be a creditor or Managed Investment Schemes (MIS) member (or a professional advisor to a creditor or member) in relation to the Forest Enterprises Australia (FEA) group in order to receive the information about the insolvencies accessed via the links below.
By accessing either of the links below, you declare that you are a creditor or MIS member of a company within the FEA group (or a professional advisor thereto) and agree not to communicate any information contained on the linked webpages or documents to any person other than another creditor or MIS member without the express written consent of Deloitte Touche Tohmatsu or unless otherwise compelled by law.
By accessing any of the links below, you also agree to indemnify Deloitte Touche Tohmatsu in respect of any liability to which they are exposed if your declaration is false and as a consequence of that falsity.
I accept the statement above and wish to access the Notice to Growers.
For additional information, Growers may also wish to view the key court documents in the Declarations Proceeding.
I accept the statement above and wish to access the key court documents.
On 9 March 2012, the High Court rejected an application brought by FEAP (at the instigation of its Deed Administrators, BRI Ferrier) for special leave to appeal against the judgment of the Full Federal Court in favour of the Receivers and Managers of FEA and its associated entities.
The judgment of the Full Federal Court found that FEAP was not entitled to set-off amounts totalling $11 million against rent owing by FEAP to FEA.
FEAP has also been ordered to pay the Receivers and Managers' costs in respect of each of the proceeding before the primary Judge, the appeal in the Full Federal Court and the application for special leave to the High Court, and recovery of those costs orders is being pursued.
ASIC has relieved Forest Enterprises Australia Limited (Subject to Deed of Company Arrangement)(Receivers and Managers Appointed) from Part 2M.3 of the Corporations Act to lodge financial reports for the financial years and half-years up to and including the financial half-year ended 31 December 2013.
ASIC s111AT Instrument 14 January 2014 |


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Williams-Sonoma has launched a new, direct-to-consumer brand, Mark and Graham, which specializes in personalized gifts and accessories.
The single cup brewing trend as arrived at Williams-Sonoma in the form of the Starbucks' deluxe Verismo System 585.
Williams-Sonoma's net revenues increased 6.1% to $818 million from $771 million in the first quarter of fiscal 2011 ended May 1, 2011.
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Williams-Sonoma has announced that Mary Ann Casati and Lorraine Twohill have been elected to its board of directors.
Williams-Sonoma Inc. reported Thursday that profit for the third quarter rose 19% to $43.4 million, from $36.5 million in the same period last year.
Williams-Sonoma reported that net income for the quarter ended May 1 jumped 62% to $31.6 million, from $19.5 million a year earlier, topping company expectations.


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GMG Racing GT3-RS Monoblock Wheel, 19" X 12", GT3-RS Red. Fits All 997 With Center Lock Hubs. Offset ET 46
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GMG World Challenge wheels are lightweight and fitment specific for Porsche 993, 996, 997 (GT3, GT2, Turbo, RS), Cayman, Boxster, Panamera and Cayenne. GMG WC 18" center lock wheels clear Porsche PCCB calipers and big kits from Brembo, Stoptech, AP Racing and Alcon. GMG World Challenge wheels are direct bolt on replacements, retaining all OE mounting hardware and TPMS sensors. GMG World Challenge wheels are built to TUV specifications and exceed JWL specification.
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