text:
A$AP Rocky Addresses "Long.Live.A$AP" Leak & A$AP Mob Success
A$AP Rocky opines on his debut album's leak, as well as his crew's individual shine.
While it's no secret that A$AP Rocky's debut album Long.Live.A$AP has leaked, the young emcee is taking a positive approach to the matter.
"I've been waiting for people to hear this music for so damn long," admitted Rocky in an interview with Hot 97's Miss Info. "Of course I've gotta be a businessman, but before anything I'm an artist. The album leaked, and I'ma leave it up to my dependable label, which I rely on to fix all that. That's the business aspect. I made my art, y'all love it, and that's all I care about, and I just wanna thank everybody who was anticipating this."
Additionally, Rocky addressed his A$AP crew's individual success.
"That's what I wanted from the jump," explained the Harlem rapper. "I wanted everybody to shine individually. I just wanted it to be organic. We all came up together, and everybody had individual talent. It's not just me. Anybody could tell you, walking up and down these streets... everybody always fucked with us because there was always something about us that was interesting."
Watch the interview below:
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Summary: Agrin NtA domain
Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.
This is the Wikipedia entry entitled "Agrin". More...
Agrin Edit Wikipedia article
Agrin NtA domain | |||||||||
Identifiers | |||||||||
Symbol | NtA | ||||||||
Pfam | PF03146 | ||||||||
InterPro | IPR004850 | ||||||||
SCOP | 1jc7 | ||||||||
SUPERFAMILY | 1jc7 | ||||||||
Agrin is a large proteoglycan whose best-characterised role is in the development of the neuromuscular junction during embryogenesis. Agrin is named based on its involvement in the aggregation of acetylcholine receptors during synaptogenesis. In humans, this protein is encoded by the AGRN gene.[2][3][4]
This protein has nine domains homologous to protease inhibitors.[5] It may also have functions in other tissues and during other stages of development. It is a major proteoglycan component in the glomerular basement membrane and may play a role in the renal filtration and cell-matrix interactions.[6]
Agrin was first identified by the U.J. McMahan laboratory, Stanford University.[7]
Mechanism of action[edit]
During development, the growing end of motor neuron axons secrete a protein called agrin.[8] This protein binds to several receptors on the surface of skeletal muscle. The receptor that seems to be required for formation of the neuromuscular junction (NMJ) is called the MuSK receptor (Muscle specific kinase).[9][10] MuSK is a receptor tyrosine kinase - meaning that it induces cellular signaling by causing the addition of phosphate molecules to particular tyrosines on itself and on proteins that bind the cytoplasmic domain of the receptor.
In addition to MuSK, agrin binds several other proteins on the surface of muscle, including dystroglycan and laminin. It is seen that these additional binding steps are required to stabilize the NMJ.
The requirement for Agrin and MuSK in the formation of the NMJ was demonstrated primarily by "knockout" mouse studies. In mice that are deficient for either protein, the neuromuscular junction does not form.[11] Many other proteins also comprise the NMJ, and are required to maintain its integrity. For example, MuSK also binds a protein called "dishevelled" (Dvl), which is in the Wnt signalling pathway. Dvl is additionally required for MuSK-mediated clustering of AChRs, since inhibition of Dvl blocks clustering.
The nerve secretes agrin, resulting in phosphorylation of the MuSK receptor.
It seems that the MuSK receptor recruits casein kinase 2, which is required for clustering.[12]
A protein called rapsyn is then recruited to the primary MuSK scaffold, to induce the additional clustering of acetylcholine receptors (AChR). This is thought of as the secondary scaffold. A protein called Dok-7 has shown to be additionally required for the formation of the secondary scaffold; it is apparently recruited after MuSK phosphorylation and before acetylcholine receptors are clustered.
There are three potential heparan sulfate (HS) attachment sites within the primary structure of agrin, but it is thought that only two of these actually carry HS chains when the protein is expressed.
In fact, one study concluded that at least two attachment sites are necessary by inducing synthetic agents. Since agrin fragments induce acetylcholine receptor aggregation as well as phosphorylation of the MuSK receptor, researchers spliced them and found that the variant did not trigger phosphorylation. It has also been shown that the G3 domain of agrin is very plastic, meaning it can discriminate between binding partners for a better fit.[1]
Heparan sulfate glycosaminoglycans covalently linked to the agrin protein have been shown to play a role in the clustering of AChR. Interference in the correct formation of heparan sulfate through the addition of chlorate to skeletal muscle cell culture results in a decrease in the frequency of spontaneous acetylcholine receptor (AChR) clustering. It may be that rather than solely binding directly to the agrin protein core a number of components of the secondary scaffold may also interact with its heparan sulfate side-chains.[13]
A role in the retention of anionic macromolecules within the vasculature has also been suggested for agrin-linked HS at the glomerular or alveolar basement membrane.
- ^ a b PDB 1PZ7; Stetefeld, J., Alexandrescu, A.T., Maciejewski, M.W., Jenny, M., Rathgeb-Szabo, K., Schulthess, T., Landwehr, R., Frank, S., Ruegg, M.A., Kammerer, R.A. (2004). "Modulation of agrin function by alternative splicing and Ca2+ binding". Structure 12: 503–515. doi:10.2210/pdb1pz7/pdb. PMID 15016366.
- ^ Rupp F, Payan DG, Magill-Solc C, Cowan DM, Scheller RH (May 1991). "Structure and expression of a rat agrin". Neuron 6 (5): 811–23. doi:10.1016/0896-6273(91)90177-2. PMID 1851019.
- ^ Kröger S, Schröder JE (October 2002). "Agrin in the developing CNS: new roles for a synapse organizer". News Physiol. Sci. 17 (5): 207–12. doi:10.1152/nips.01390.2002 (inactive 2010-08-28). PMID 12270958.
- ^ Groffen AJ, Buskens CA, van Kuppevelt TH, Veerkamp JH, Monnens LA, van den Heuvel LP (May 1998). "Primary structure and high expression of human agrin in basement membranes of adult lung and kidney". Eur. J. Biochem. 254 (1): 123–8. doi:10.1046/j.1432-1327.1998.2540123.x. PMID 9652404.
- ^ Tsen G, Halfter W, Kröger S, Cole GJ. (1995). "Agrin is a heparan sulfate proteoglycan". J Biol Chem 270 (7): 3392–3399. doi:10.1074/jbc.270.7.3392. PMID 7852425.
- ^ Groffen AJ, Ruegg MA, Dijkman H, van de Velden TJ, Buskens CA, van den Born J, Assmann KJ, Monnens LA, Veerkamp JH, van den Heuvel LP. (1998). "Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane". J Histochem Cytochem 46 (1): 19–27. doi:10.1177/002215549804600104. PMID 9405491.
- ^ Magill C, Reist NE, Fallon JR, Nitkin RM, Wallace BG, McMahan UJ (1987). "Agrin". Prog. Brain Res. Progress in Brain Research 71: 391–6. doi:10.1016/S0079-6123(08)61840-3. ISBN 978-0-444-80814-1. PMID 3035610.
- ^ Sanes JR, Lichtman JW (November 2001). "Induction, assembly, maturation and maintenance of a postsynaptic apparatus". Nat. Rev. Neurosci. 2 (11): 791–805. doi:10.1038/35097557. PMID 11715056.
- ^ Glass DJ, Bowen DC, Stitt TN, Radziejewski C, Bruno J, Ryan TE, Gies DR, Shah S, Mattsson K, Burden SJ, DiStefano PS, Valenzuela DM, DeChiara TM, Yancopoulos GD (May 1996). "Agrin acts via a MuSK receptor complex". Cell 85 (4): 513–23. doi:10.1016/S0092-8674(00)81252-0. PMID 8653787.
- ^ Sanes JR, Apel ED, Gautam M, Glass D, Grady RM, Martin PT, Nichol MC, Yancopoulos GD (May 1998). "Agrin receptors at the skeletal neuromuscular junction". Ann. N. Y. Acad. Sci. 841: 1–13. doi:10.1111/j.1749-6632.1998.tb10905.x. PMID 9668217.
- ^ Gautam M, Noakes PG, Moscoso L, Rupp F, Scheller RH, Merlie JP, Sanes JR (May 1996). "Defective neuromuscular synaptogenesis in agrin-deficient mutant mice". Cell 85 (4): 525–35. doi:10.1016/S0092-8674(00)81253-2. PMID 8653788.
- ^ Cheusova T, Khan MA, Schubert SW, Gavin AC, Buchou T, Jacob G, Sticht H, Allende J, Boldyreff B, Brenner HR, Hashemolhosseini S (July 2006). "Casein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromuscular junction". Genes Dev. 20 (13): 1800–16. doi:10.1101/gad.375206. PMC 1522076. PMID 16818610.
- ^ McDonnell KM, Grow WA (2004). "Reduced glycosaminoglycan sulfation diminishes the agrin signal transduction pathway". Dev. Neurosci. 26 (1): 1–10. doi:10.1159/000080706. PMID 15509893.
This page is based on a Wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.
This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.
Agrin NtA domain Provide feedback
Agrin is a multidomain heparan sulphate proteoglycan, that is a key organiser for the induction of postsynaptic specialisations at the neuromuscular junction. Binding of agrin to basement membranes requires the amino terminal (NtA) domain [2]. This region mediates high affinity interaction with the coiled-coil domain of laminins. The binding of agrin to laminins via the NtA domain is subject to tissue-specific regulation. The NtA domain-containing form of agrin is expressed in non-neuronal cells or in neurons that project to non-neuronal cell such as motor neurons. The structure of this domain is an OB-fold [1].
Literature references
Stetefeld J, Jenny M, Schulthess T, Landwehr R, Schumacher B, Frank S, Ruegg MA, Engel J, Kammerer RA; , Nat Struct Biol 2001;8:705-709.: The laminin-binding domain of agrin is structurally related to N-TIMP-1. PUBMED:11473262 EPMC:11473262
Denzer AJ, Hauser DM, Gesemann M, Ruegg MA; , Cell Tissue Res 1997;290:357-365.: Synaptic differentiation: the role of agrin in the formation and maintenance of the neuromuscular junction. PUBMED:9321698 EPMC:9321698
External database links
Pseudofam: | PF03146 |
SCOP: | 1jc7 |
SYSTERS: | NtA |
This tab holds annotation information from the InterPro database.
InterPro entry IPR004850
Agrin is a multidomain heparan sulphate proteoglycan, that is a key organiser for the induction of postsynaptic specializations at the neuromuscular junction. Binding of agrin to basement membranes requires the amino terminal (NtA) domain [PUBMED:9321698]. This region mediates high affinity interaction with the coiled-coil domain of laminins. The binding of agrin to laminins via the NtA domain is subject to tissue-specific regulation. The NtA domain-containing form of agrin is expressed in non-neuronal cells or in neurons that project to non-neuronal cell such as motor neurons. The NtA domain forms the most N-terminal part, followed by 9 Kazal-like domains and 2 LE domains. The C-terminal part consists of a SEA domain, 4 EGF-like domains and 3 Laminin G domains, responsible for the clustering of acetylcholine receptors [PUBMED:11473262].
Tertiairy structures show that the NtA domain folds as a beta-barrel core flanked by N- and C-terminal helical regions. The core of the domain consists of 5 beta-strands that form 2 beta-sheets. The structure belongs to the OB fold family and shows similarity with the protease inhibition domain of TIMP-1, suggesting alternative functions for agrin in addition to synaptogenic activity [PUBMED:11473262]. Residues Leu 117 and Val 124 in helix 3 of the NtA domain are essential for binding to the laminin gamma1 chain [PUBMED:12554653].
Gene Ontology
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
Cellular component | basal lamina (GO:0005605) |
Molecular function | laminin binding (GO:0043236) |
Biological process | receptor clustering (GO:0043113) |
G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) |
Domain organisation
Below is a listing of the unique domain organisations or architectures in which this domain is found. More...
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We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database using the family HMM. We also generate alignments using four representative proteomes (RP) sets, the NCBI sequence database, and our metagenomics sequence database. More...
View options
We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.
Seed (2) |
Full (48) |
Representative proteomes | NCBI (43) |
Meta (0) |
Jalview | ||||||||
PP/heatmap | 1 | |||||||
Pfam viewer |
1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
Format an alignment
Download options
We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.
Seed (2) |
Full (48) |
Representative proteomes | NCBI (43) |
Meta (0) |
Raw Stockholm | ||||||||
Gzipped |
You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.
External links
MyHits provides a collection of tools to handle multiple sequence alignments. For example, one can refine a seed alignment (sequence addition or removal, re-alignment or manual edition) and then search databases for remote homologs using HMMER3.
HMM logo
HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...
This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.
Note: You can also download the data file for the tree.
Curation and family details
This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.
Seed source: | [1] |
Previous IDs: | none |
Type: | Domain |
Author: | Bateman A |
Number in seed: | 2 |
Number in full: | 48 |
Average length of the domain: | 116.40 aa |
Average identity of full alignment: | 73 % |
Average coverage of the sequence by the domain: | 11.37 % |
HMM information
HMM build commands: |
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
Model details: |
Model length: | 128 | ||||||||||||
Family (HMM) version: | 10 | ||||||||||||
Download: | download the raw HMM for this family |
Species distribution
Sunburst controls
ShowThis visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...
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Please note: for large trees this can take some time. While the tree is loading, you can safely switch away from this tab but if you browse away from the family page entirely, the tree will not be loaded.
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the NtA domain has been found. There are 4 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
Loading structure mapping...

subset: commoncrawl


text:
I think there is a difference. Let's say you're in an ice cream parlour. Someone asks you:
I don't think that you can substitute flavour for taste, because "taste" is subjective feeling that is produced by a particular food. Most people will however agree whether a particular type of ice cream is chocolate or not, there's nothing subjective about that.Which flavour do you want – chocolate or vanilla?


text:
How Does Google Improve Search?
Have you ever wondered how Google improves search? In particular, the process they go through to refine and enhance all their search algorithms. This has become a topical issue now that it is harder to access the Google News Archive (see The Death of Google News Archive).
The process sounds complicated, but in fact it is interesting and easy to understand. Watch this video from Google to gain insight into how Google makes hundreds of enhancements to search every year. This 3 1/2 minute video is something every genealogist should watch. In a couple of minutes it will give you more insight than reading most books on the topic.
Finally, do you want to get the inside scoop on current and future developments from Google? Check out the Google Inside Search website.
Tweet |
Further Reading
The Death of Google News Archive


text:
The Care Quality Commission checks whether hospitals, care homes and care services are meeting government standards. Visit our website at www.cqc.org.uk.
Every registered provider will pay a single annual fee on the same date each year. This fee will cover all registration and compliance requirements for all locations.
Full details of the scheme for 2013/14, which is applicable from 1 April 2013, are available to download below. We have also published our regulatory impact assessment on the scheme.
Fees calculator
Use our fees calculator to find out how much the fee you pay should be.
Fees consultation 2013/14
Find out more about the Consultation on fees for registered health and social care services we carried out last year, which helped us develop your fees for 2013/14.
You can also download our response to the consultation and our analysis of the feedback we received below.
Our long-term fees strategy
Over the next three years, we will continue to develop our fees model for all the sectors we regulate in line with CQC's wider strategy.
Read about our overall approach to fees between 2013 to 2016 below.
Our approach to fees follows the six principles below.
- To be fair
- Reflect costs
- Contribute to our regulatory model
- Be simple
- Be transparent
- Be visionary
A fees advisory panel has been created, made up of providers and their representative organisations from across the sectors we regulate. This panel is considering our plans and helping to inform the long-term direction of our fees model.
We will carry out another public consultation at the end of this year, which will consider the next set of changes to the model for 2014/15.
Key information
Detailed guidance for providers about the fees scheme will be published during the week of 8 April 2013.
In the meantime, you can find the answers to frequently asked questions below.
When is my fee due?
You will be invoiced on the same date each year. The date will depend on your specific circumstances, but is usually the anniversary of the date of your registration.
Providers that are new to registration will receive their first annual fee invoice once their registration has been completed and they have received their certificate of registration.
You will be sent your invoice in advance of your payment due date.
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You can find out how much your fee will be using the calculator above.
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Full details of how to pay will be outlined in your invoice.
Who do I contact if I have any questions about my fee?
You can contact our National Customer Service Centre if you have any questions about registration fees.
Email: email@example.com
Telephone: 03000 616161
Or you can write to us:
CQC National Customer Service Centre
Newcastle upon Tyne
How have you calculated fees for GP providers with one location?
For GP providers registered with one location, the fee we charge will be determined by their registered patient list size. List sizes are grouped into four incremental bands, with annual fee charges ranging from £550 for the smallest band to £850 for the largest.
We have calculated list size using publicly available information from the NHS Business Services Authority. Patient list size for all GP surgeries is published there quarterly.
To avoid any disadvantage as a result of any seasonal variations, we have calculated list sizes for each practice using an average across four consecutive quarters (from the reports dated 1 January 2012, 1 April 2012, 1 July 2012 and 1 October 2012).
Providers of NHS primary medical services who are registered for one location can check their average list size against this information and then refer to our Fees calculator above to see which band they match to and what the fee charged will be.
The fee band and the amount of annual fee due will be shown on the invoice that NHS GPs will receive soon.
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If you are dealing with a fees invoice from 2012/13, you may still need to refer to last year's fees scheme. We have made these available below.
Concerns about care?
Speak up and tell us on 03000 61 61 61, firstname.lastname@example.com, or our online form
You can also share your experience of a service with us.


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Published on | Description | |
SaturdayDecember 6, 2008 |
Donated houses benefit Valley foundationHarold Yudkin '33 died in 2004, but his sense of philanthropy is still being felt in Derby, Conn., where he lived, practiced law and was a commercial developer for many years. Two homes that Yudkin and his widow, Selma, owned in Derby are being donated to the Valley Community Foundation, which will sell them to establish a fund in their names. |


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With Noel hurt, Kentucky may have lost more than a game |
GAINESVILLE, Fla. -- Kentucky assistant John Robic emerged from the locker room Tuesday night and looked around for someone in charge. Then he made a request that shattered any illusion that forward Nerlens Noel's left knee injury might have been less serious than it looked and sounded. "Can we get a wheelchair?" Robic asked.
Noel, a towel over his face, was wheeled through the bowels of the O'Connell Center and taken to the hospital. Kentucky's season might have gone with him.
This wasn't a great Wildcats team to begin with. Tuesday's 69-52 loss to Florida was no upset. The older, more polished, more skilled team looked like the older, more polished, more skilled team. With Noel, a 6-foot-10 forward who entered the week leading the nation with 4.5 blocks a game, Kentucky would have had a puncher's chance at going deep in the NCAA tournament because of its superior athleticism. If the injury is as serious as it looked and sounded, whether Kentucky will make the tournament at all becomes a legitimate question.
Afterward, Kentucky coach John Calipari declined to discuss how the Wildcats might look without Noel. "I'm not going to think about that," Calipari said as Noel was being transported to Shands Hospital for tests on the knee. "I'm worried about the kid right now."
Last April, the convenient narrative for lazy writers who wanted to file their columns without actually watching the games at the Final Four was that Calipari's national title team of one-and-done wonders had killed amateurism. Cal would reload with another group of baby superstars and steamroll everyone every year. If anything, this year's group of potential one-and-dones has proven why the 2011-12 Wildcats were the first team since the NBA instituted an age limit in prior to the 2006 draft to win the national title with a one-and-done player on the roster. Relying on freshmen -- no matter how talented -- remains a dicey proposition.
One rarely wins a title by collecting highly sought-after recruits, rolling the ball out and watching them dominate. National titles require superior skill, excellent chemistry and at least a little luck. Calipari got lucky last year because he added an athletic, willing-to-learn point guard (Marquis Teague) and two selfless freshmen who happened to be absurdly talented (Anthony Davis and Michael Kidd-Gilchrist) to a rotation that included a seen-it-all senior (Darius Miller) and two sophomores (Doron Lamb and Terrence Jones) who probably could have gone to the NBA after helping Kentucky reach the Final Four as freshmen. That group had instant chemistry, probably because Davis and Kidd-Gilchrist were the rare top recruits who arrived on campus caring more about the team than themselves. Coaches always want to recruit such players, but until they get them on the practice court, they don't really know what they have.
Noel is the closest thing this group of Wildcats had to a Davis or a Kidd-Gilchrist. He is a lottery pick who rarely gives up on a possession on either end of the floor. He fights for rebounds. He blocks shots but doesn't do it so wildly that he gets himself in foul trouble every night. With Noel, the Wildcats looked lost against Florida -- which is precisely the type of well-rounded, veteran-heavy team this season's eventual national champ will have to beat two or three times during this year's tournament. Without Noel, Kentucky looked hopeless.
It happened as Noel corrected a mistake with 8:03 remaining and the Wildcats trailing by 12. Florida guard Mike Rosario had just picked off a pass intended for Noel near midcourt. As Rosario closed in for a layup, Noel sprinted behind him. Before Rosario could release the ball, Noel unfurled and swatted the ball with his left hand. He landed awkwardly. Then he grabbed his left knee. Video shot by Julie Quittner of the Gainesville Television Network from the baseline appeared to show Noel attempting to pop his kneecap back into place. Then he crumpled. As Noel screamed, Calipari hovered over his fallen star. Trainers examined the knee and got Noel upright, but he could put no weight on it. The five Kentucky players who were checked into the game ran to Noel and carried him off the court. Guards Julius Mays and Archie Goodwin did the heaviest lifting. "We're all brothers," Mays said. "Win, lose or draw. We've always got each other's backs."
Afterward, Florida coach Billy Donovan pointed out the sad irony of the injury. "The injury came from a hustle play," Donovan said. "It kind of embodies who he is as a player. He's a hustle-play guy."
Donovan knows exactly how it feels to lose a team-first, hustle-play guy. Last week, Florida lost forward Will Yeguete to a knee injury at Arkansas. Without their glue guy, the Gators looked aimless in a blowout loss. (Yeguete is likely out for the remainder of the regular season but should return for the postseason following arthroscopic surgery.) But Florida is a deep, veteran team. After a few practices and a game against Mississippi State to regroup, the Gators adjusted their roles. Tuesday, junior Casey Prather provided a different -- think Gorilla instead of Krazy -- but still effective brand of glue. In 23 minutes, Prather scored 12 points on 6-of-8 shooting, blocked two shots, dished out two assists and played smothering defense. He didn't provide the post muscle Yeguete would have, but Prather gave the Wildcats another X-factor with which to contend.
They were not ready for Prather, nor were they ready for the other four Gators who finished with double-figure points. Calipari said as much in the post-mortem.
On his team's maturity: "Our young guys looked like deer in headlights."
On his team's physicality (or lack thereof): "This was almost a game that exposed us a little bit physically."
On his team's preparedness: "It's probably the coaching. It's probably on me more than anyone else."
In the aftermath of Noel's injury, Calipari will have to set aside the self-flagellation and earn his paycheck. Without Noel, he'll need the coaching job of his life to make this group competitive against elite teams. Even when he had Noel, Calipari tried every combination he could. His roster is his roster. It's up to him to maximize what he has left.
Otherwise, Kentucky's hopes might have buckled with Noel's knee.


text:
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Civil Air Patrol training draws on 4 states
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The Portable Chekhov
Portable Library
Anton Chekhov - Author
ISBN 9780140150353 | 640 pages | 25 Aug 1977 | Penguin | 5.07 x 7.79in | 18 - AND UP
Summary of The Portable Chekhov
Summary of The Portable Chekhov
Reviews for The Portable Chekhov
An Excerpt from The Portable Chekhov
Edited and with an introduction by Avrahm Yarmolinsky, The Portable Chekhov presents twenty-eight of Chekhov's best stories, chosen as particularly representative of his many-sided portrayal of the human comedy - including "The Kiss", "The Darling", and "In theTavine" - as well as two complete plays: The Boor, an example of Chekhov's earlier dramatic work, and The Cherry Orchard, his last and finest play. In addition, this volume includes a selection of letters, candidly revealing of Chekhov's impassioned convictions on life and art, his high aspirations, his marriage, and his omnipresent compassion.
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Home ›10/3/2012 Listening Lounge
Everybody Scream!!! from The Truth
Warm up that saddle and pick up the pace, we are going inside the minds of two very competitive women... in spin class!!!
Glass Not Glitter from This Land Press
Neighbors of the Murrah Federal building recall the 1995 bombing that altered the life and culture of Oklahoma City.
Energy Brat from Youth Radio
Antony Jaureguí grew up in sunny Southern California, and has never worried much about where energy comes from and how much he uses.
Workshop by Billy Collins
Antony JBilly Collins bites the hand that feeds him.
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He says the best way to contain fires is to not let them start in the first place.
"A lot of these fires are man caused," Herbert said. "We need to understand here in Utah that an ounce of prevention is worth a pound of cure."
Utah's tender dry conditions can cause devastating wildfires with any little misstep. There are approximately five fires burning in remote areas of Southern Utah.
"The problem is fires start and they run those canyons," State Fire Marshal Coy Porter said. "They're very difficult to contain."
Utah State Forester Dick Buehler reminds the public of last year's record season when Utah saw approximately 1500 wildfires. He said over 700 of those fires were man-made and could have been prevented.
"That's the message we really want to put out, be vigilant as the governor said," Buehler added. "Be careful with fire and make sure you know what you're doing."
State officials offered these tips to keep the public safe:
-Never leave campfires unattended
-Always have water to douse a fire
-Keep ATV's on trails
-Don't park cars over weeds and tall grass
-Only use authorized fireworks
-Don't use exploding targets if you go shooting
"The best way to prevent fires is to use a little common sense," Herbert added.
State officials hope the message sticks as we approach the Fourth of July and Pioneer Days.
"Just be careful," Porter added. "Celebrate, but be responsible."


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Office of Student Orientation, Leadership and Engagement
MenuOrientation Leaders |
Orientation Leaders (OLs) are students that serve as role models to help new students at TAMIU adjust to the rigors of being a college student. OLs assist with Freshman Student Orientation, The Dustdevil Transition and International Student Orientation. Aside from guiding new students as they begin their studies at TAMIU, OLs are also responsible for providing the historical background of TAMIU through campus tours, answering University related questions, and implementing unique ideas for each orientation program. OLs are expected to be possess excellent communication and leadership skills, as well as promoting enthusiasm, creativity, and integrity in all they do.
Being an Orientation Leader will provide students with a valuable opportunity to gain leadership experience and develop the necessary skills to give back to the community. The program is composed of numerous training/leadership sessions and activities throughout the spring and summer months.
Qualifications and Eligibility
Interested students are expected to attend all training sessions during the academic year and play an active role in all freshman and transfer student orientation sessions during the summer. Dusty Camp and The Dustdevil Transition days will be provided with sufficient notice.
- Be enrolled full-time for the Spring and Fall semesters before and after all summer orientation sessions.
- Have a cumulative GPA of 2.5 or above.
- Have completed a minimum of 12 semester credit hours by the end of Fall semester.
- Be a current TAMIU undergraduate or graduate full-time student in good standing.
- Be eligible to work for TAMIU.
Orientation Leader Application
2013 Orientation Leaders |
Francisco "Franky" Adame '15 |
Rafael "Rafa" Benavides '16 |
Jackelyn "Jackie" Briseno '15 |
Hometown: Laredo, TX |
Hometown: Zapata, TX |
Hometown: Laredo, TX |
Major: Mathematics |
Major: Biology |
Major: Political Science/English |
Alejandro "Alex" Cruz '14 |
Jose Dovalina '15 |
Luis Garza '15 |
Hometown: Laredo, TX |
Hometown: Laredo, TX |
Hometown: Dallas, TX |
Major: Marketing |
Major: Marketing |
Major: Business Administration |
Jazmin Gibeaut '14 |
Jorge Gonzalez '16 |
Stephanie Martinez '16 |
Hometown: Laredo, TX |
Hometown: Laredo, TX |
Hometown: Laredo, TX |
Major: Communication |
Major: Systems Engineering |
Major: Communication |
Crystal Medrano '16 |
Liliana "Lily" Olivares '15 |
Nataly Perez '14 |
Hometown: Roma, TX |
Hometown: Roma, TX |
Hometown: Laredo, TX |
Major: Communication Disorders |
Major: Biology |
Major: History |
Jessica Porras '16 |
Ana Lu Ramirez '15 |
Gloria Rios '15 |
Hometown: Lake Jackson, TX |
Hometown: Nuevo Laredo, MX |
Hometown: Seguin, TX |
Major: Communication Disorders |
Major: Communication |
Major: Nursing |
Mariana Rodriguez '14 |
Mara Schaffler '15 |
Aileen Terrazas '15 |
Hometown: Laredo, TX |
Hometown: Nuevo Laredo, MX |
Hometown: Laredo, TX |
Major: English |
Major: Communication |
Major: Psychology |
Angela Vela '16 |
Erika Zamora '14 |
Interested in |
Hometown: Laredo, TX |
Hometown: Laredo, TX |
being an OL? |
Major: English |
Major: Early Childhood Education |
Related Institutional Goals/Principles
Imperative 1: Students | 1.1 Attract and admit a diverse and international student body. |
1.2 Increase enrollment, retention, and graduation rates. | |
1.3 Prepare students for successful leadership roles. | |
1.4 Engage students in activities that enrich their lives. | |
1.5 Provide programs and services that support established student outcomes. | |
Imperative 3: Teaching and Learning | 3.1 Establish and pursue student learning outcomes appropriate for each program and engage in systematic assessment and use of results for continuous quality improvement. |
Undergraduate Learning Principle 1: Respective and Expressive Communication Skills |
Undergraduate Learning Principle 2: Critical Thinking | |
Undergraduate Learning Principle 3: Integration and Application of Knowledge |
Undergraduate Learning Principle 4: Understanding Society and Culture |
Undergraduate Learning Principle 5: Appreciating Values and Ethics |
TAMIU Trailblazers: Personal Enrichment (Engagement Stage) |
Student Center Suite 226
5201 University Blvd., Laredo, TX 78041-1900
(956) 326-2280 or (956) 326-2281
Fax: (956) 326-2279
E-mail: email@example.com


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Map Collections
Churchman, John, 1753-1805.
Churruca y Elorza, Cosme Damián de, 1761-1805.
Cierto, Andres.
Cierto, Balentin.
Cincinnati Railway.
Cincinnati Southern Railway Company.
Cincinnati, Virginia, and Carolina Railway.
Cinquin, Rene.
Citti, L. F.
City of Los Angeles Board of Water and Power Commissioners.
Clark & Wagner.
Clark, Alvin.
Clark, Benjamin A.
Clark, Jacob P.
Clark, John S., Col.
Clark, Richard.
Clark, W. P.
Clark, William, 1770-1838.
Clarke, H. Wadsworth.
Clarke, Thomas (Engraver)
Clarke, W. B.
Clarke, William F.
Clarkson, Matthew, 1733-1800.
Clason Map Co.
Clauss, Otto.
Clayton & Van Norden.
Clayton, James A. (James Atkins), 1831-1896.
Cleaver, Kimber.
Clements, James E.
Clemes, Andres.
Cleveland & Toledo Railroad.
Cleveland and Mahoning Rail Road Company.
Clinton, Henry, Sir, 1738?-1795.
Clohessy & Strengele.
Clough, J.
Cluss, A.
Clüver, Philipp, 1580-1622.
Coal and Iron Railway.
Coate, Marmaduke.
Coates, Marmaduke.
Coburn, Eleazer.
Cocheco Railroad.
Cock, Hieronymus, approximately 1510-1570.
Cockburn, Jas.
Cockerell, C. R. (Charles Robert), 1788-1863.
Cococi, Alexandre Mariano.
Coffman, David J., b. 1839.
Coghlan, Wm. C. (William C.)
Colby & Stuart.
Colby, George N.
Colby, Hall.
Cole, B. (Benjamin)
Cole, J. F.
Colesworthy, Samuel Hodgson, 1808-
Colles, Christopher, 1738-1816.
Collet, John.
Collier & Cleaveland Lith. Co.
Collin, E., engraver.
Collins, John, -1795.
Collins, William P.
Collot, Georges-Henri-Victor, 1750-1805.
Colman, Samuel, 1799-
Colnett, James, 1755?-1806.
Coloney & Fairchild.
Colonna, B. A. (Benjamin Allison)
Colonna, B. Allison.
Colton, G. Woolworth (George Woolworth), 1827-1901.
Colton, J. H. (Joseph Hutchins), 1800-1893.
Columbia Planograph Co.
Columbus and Pensacola Railroad.
Columbus, Chicago, and Indiana Central Railway.
Colville Map Co.
Commission européenne du Danube.
Compagnie belge de colonisation.
Compagnie universelle du canal interocéanique de Panama. Chef de section.
Companhia Lithographica Hartmann-Reichenbach.
Compañía Litográfica y Tipográfica, S.A.
Comparative Synoptical Chart Co., Limited.
Compton, H. T. (Harry Trueman)
Compton, Richard J.
Comstock, C. B. (Cyprus Ballou), 1831-1910.
Comstock, C. B. (Cyrus Ballou), 1831-1910.
Comstock, Cyrus B.
Condit, Wright & Hayden.
Cone, Joseph.
Coneys, W. T.
Confederate States of America. Army of Northern Virginia. Corps, 2nd. Engineer Office.
Confederate States of America. Army of Northern Virginia. Engineer Office.
Confederate States of America. Army. Arkansas District. Topographical Bureau.
Confederate States of America. Army. Corps of Engineers.
Confederate States of America. Army. Department of Northern Virginia.
Confederate States of America. Army. Department of Northern Virginia. Chief Engineer's Office.
Confederate States of America. Army. Dept. of Northern Virginia. Chief Engineer's Office.
Confederate States of America. Army. Military Division of the West.
Confederate States of America. Navy Dept. Office of Ordnance and Hydrography.
Congressional Cartography Program (Library of Congress)
Connecticut Academy of Arts and Sciences.
Connecticut Western Railroad Co.


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2010 Honda Accord Sedan
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Ending the Failed Experiment: A High Court Marriage Challenge to Civil Unions in New Jersey
on Mar 25, 2010 at 10:18 amFreedom to Marry's Evan Wolfson and Hayley Gorenberg, Deputy Legal Director of Lambda Legal, discuss Lambda Legal's return to the New Jersey Supreme Court to win the freedom to marry.
Opinion: N.J.'s Freedom to Marry Debate - Back to Court because Lawmakers failed
on Mar 24, 2010 at 10:04 amWhen the state Supreme Court ruled in 2006 that same-sex couples must have the same rights as heterosexual couples under New Jersey law, the justices ducked the obvious question: Can gay couples get married? They left that question to the state Legislature, which found another way to avoid it, passing a law that established civil unions. They're just like marriages, the law essentially says, but with a different name.
National Center for Lesbian Rights: Why LGBT People Must Demand Immigration Reform
on Mar 19, 2010 at 04:42 pmThere is a large battle looming in Washington over legislation to reform our nation's immigration laws. This coming Sunday, March 21, many LGBT immigrants, their families, and allies will march in support of immigration reform. Now is the time for us, as LGBT individuals, families, and communities, to understand why immigration reform is so critical.
Aging issues can be tougher for same-sex couples
on Mar 18, 2010 at 02:51 pmThough aging is tough for everyone, it tends to be tougher for people who are gay, according to a report presented Wednesday at the annual conference of the National Council on Aging and the American Society on Aging in Chicago, Illinois.
Advocacy Groups Release FAQ Guide for Maryland Same-Sex Couples Married Out of State
on Mar 10, 2010 at 11:58 amOn Monday, March 8, Lambda Legal, American Civil Liberties Union of Maryland, the National Center for Lesbian Rights, Equality Maryland, and the American Civil Liberties Union released a Frequently Asked Questions (FAQ) Guide for same-sex couples in Maryland who married out of state.
AFL-CIO Convention Passes Historic Resolution on Diversity
on Sep 23, 2009 at 04:05 pmSeptember 22, 2009
Amid many speeches calling for inclusion of LGBT workers, Maine AFL-CIO President Ed Gorham spoke of the November 3rd referendum on marriage equality in Maine, saying he urged delegates to contact everyone they know in Maine to vote against Referendum 1 and support marriage equality for the LGBT community. Read the full AFL-CIO LGBT-inclusive resolution here. [Link to convention]
Professional Associations Back Marriage Equality
on Aug 10, 2009 at 05:08 pmAugust 10, 2009
Both the National Education Association (NEA) and the American Bar Association (ABA) have adopted resolutions backing GLBT rights, including the freedom to marry for gay and lesbian couples. (Link)
Unions joining marriage equality fight in New York
on Jun 05, 2009 at 11:55 amJune 5, 2009
With nine days left in the legislative session, gay rights advocates are making the final push for passage of a freedom to marry bill with help from the state's most powerful labor unions. (Link)
TALKING TO CO-WORKERS: Being Authentic Makes a Difference
on Feb 11, 2009 at 03:00 pmWhen I was first coming out, I began singing with the Gay Men's Chorus in Washington, DC. I worked at a high-powered corporate consulting firm, and was fresh off getting my MBA at Wharton. But I wasn't yet out at work. This was the early 80's, and I wasn't that sure of myself – both as a gay man and as an out professional. So I kept things to myself at work and channeled my burgeoning pride into my singing.
But one day, a colleague asked me to lunch. It turns out she had been in the audience for one of the concerts and was a lesbian, so this was her way of coming out to me and of arranging for me to come out to her. We had a great lunch that day as we shared stories of our respective girl and boy friends. It started a wonderful friendship and a great business relationship. It was, in fact, the beginning of my GLBT work network.
The really nice thing, though, was that my act of "gay pride" – singing in the chorus – helped me create a foundation for the future. It was a baseline of safety and support that I was able to draw on through-out my career.
When 5 years had passed and I was finally out to all my consulting colleagues, it made things amazingly easy for me at work when my partner and I decided to have children. The people that had gotten to know me – the real me – were so supportive. My boss at the time, one of the senior partners of the firm, threw the baby shower, and my daughter's birth was announced in the firm's newsletter – just like those of all my colleagues.
That was great while I was with the consulting firm, but eventually it was time for me to make the move into the corporate world. Yet while the prospect of finding the right place to work -- a place that would be welcoming to who I was (a gay dad at that) – seemed daunting, I now knew it mattered.
And once again, that foundation of support came through for me. I got a call from an old consulting colleague who had gone off to found Capital One, and he wanted me to join them. What a great prospect -- an opening to be part of a vibrant, growing company that wanted to revolutionize its industry! And even better, they knew me, and I knew them.
So when I asked my old friend what it was like for gay people at Capital One, he told me about one of his SVP's who was a lesbian. It turned out that when she had a commitment ceremony with her partner, the entire senior management team attended. It was a great endorsement, and I knew Capital One was the place for me.
But while I knew some of the folks there, I certainly didn't know everyone. After all, this was a company that in the first 5 years I worked there grew from 2,500 staff to over 10,000. In my role, I worked cross-functionally with people from all over the company, in cities like Richmond, Tampa and Dallas. Singing in the local gay men's chorus wasn't going to help me this time.
Instead, as I grew within Capital One, it meant constantly and frequently coming out – over and over again. Because, every time I met with someone new, I had to establish a relationship – and ideally an open and authentic one at that. What better way than to share what we have in common, and more often than not that was having kids.
However, as soon as I talked to a new team-mate about my children's latest escapade, he or she would ask about my wife. The first time this happened, I was flummoxed. Somehow it had slipped my mind that the other person didn't know I was gay. What to do? Well, I think the first time I just hemmed and hawed and adroitly shifted the subject.
I knew, though, that wasn't what I wanted to do. Instead I developed a patter if asked about my "wife": "Oh no, I'm not married. I'm gay. My partner and I have been together 17 years and we have two kids – a daughter who's now in 2nd grade and a son who's in Kindergarten."
The first time I tried this, it came out a little shaky. My colleague stopped for a second (while the mental wheels turned in her head!), and then gave me a big smile and said, "Oh that's great. Wow 17 years – when did you meet?" And then we went on and got to know each other some more. Somehow, that flood of information – and the fact she could make sense of it all – defused what could be a difficult situation. More importantly, she felt pride in her reaction, and I felt good about being authentic.
After a while, it got easier and easier, which also mattered for me, as these situations always seemed to come up when you least expected them. The honesty also meant a new colleague could trust me, and maybe most importantly, by putting a human face on being gay and being a gay parent, I had chipped away at homophobia.
Ultimately that's the lesson here. Being honest about who we are and telling our stories – even when we least expect to and even in the workplace – builds a connection in people. That connection tears down walls and builds support. It's also how I know we will ultimately win the freedom to marry.
TALKING TO CO-WORKERS: Marriage matters in Indiana too
on Feb 11, 2009 at 01:00 pmI climb telephone poles for AT&T, America's number one phone company and I am just as proud of that as my non-gay co-workers. Also like my co-workers, I feel passionately about marriage. I am part of a work group in Indianapolis where all four members of our team are married, including me and we all talk about our spouses openly and with respect. Being the authentic me with my co-workers has made a big difference in my attitudes about work and it all started when I got married.
I was blessed to find the right man in my life after years of hoping, but we had to make a trip to Canada to be married. It was an awesome experience but it should not have been necessary because we should have had that right here in Indiana. However, if I had not taken the trip and had this special wedding in another country, I would never have realized how important marriage equality was to me and be able to share that with others.
That weekend, I was able to feel just like every other straight American feels on their wedding day. That feeling is so fresh in my heart and it makes me want to share it with everyone I meet. We ran into many couples on our special day in Niagara Falls, and we all wished one another well. They seemed to be all straight couples caught up in the joy of marriage. It was amazing!
I can understand Americans having a difference of opinion on the subject of marriage equality. What I can't understand is how anyone, straight or gay, thinks that marriage between a gay couple in America will make the marriage of a straight couple any less meaningful. The couples at Niagara Falls certainly didn't and we shared in each other's joy.
Before getting married, I didn't talk much about being gay at work – my church, my weekend entertainment or the political issues impacting me as a gay man. Now, my co-workers hear about my real life every day just as I hear about the things that concern them. There are four of us guys on my team. We wear jeans and work-boots, and we are "the guys" called in for the big emergencies. We are a team, one gay and three non-gay, and we trust each other and respect one another's marriages.
Yes, I climb telephone poles for AT&T but I'm also an openly "married man" with all my co-workers and that has made all the difference in the world. Thanks Marty, Ryan and Todd.
***Greg Disney works for AT&T and lives in Indianapolis. He and Tahlib were married on January 28, 2008.


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'FRED': a CSI detective's best friend
First, we admit to some potential bias here: We're not huge fans of CSI, in whatever location--Miami, New York, Vegas, Walla Walla--so perhaps we're missing something here. Still, we can't help but think that this product is an indication that some people might be getting a wee obsessed with the whole forensics craze. (The fact that forensics can constitute a craze is disturbing enough as it is.)
Digital Intelligence's "Forensic Recovery of Evidence Device," or FRED to its friends, and its related "On Location" equipment are designed to accompany you to the … Read more


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1962 Cadillac Eldorado Biarritz Convertible, Excellent driver, always attention getter. Paint has few thin spots and chips. Drives great. new bumpers, wheels, engine recently... More
1962 Cadillac Series 622 Door Hard TopGorgeous 62 Cadillac ground up restoration.Seats Recovered, New Carpet, Recored Radiator, New Heater and Radiator Hoses, new Brake... More
1962 Cadillac Coupe Deville, This Caddy is a restored vehicle. Seems to be lowered and door handles have been shaved with poppers for the... More
For sale by ownerSeller EROL GLADAN 7734185647 [contact seller] , car is located in ILseattle washington survivor car. same owner since 1994., solid orginal car that... More
After the excess of fins which had distinguished Cadillacs only a few years before the Sixty Special reflected not only Bill Mitchells more subtle... More
1962 Cadillac flower car, manufacturer unknown, possibly modified from a DeVille four door hardtop. This car is quite rusty and beat up, but... More
CADILLAC: 1962 limousine, with divider, white, condition #2/#3, $18,000 obo. Bob, 916-632-9095 am PST, CA.... More
WANTED: got a white fiberglass parade boot for a 1962 Cadillac Eldorado for sale? 831-375-1207, CA.... More
CADILLAC: 1962 Coupe deVille, decent body, did have rust repair work done, make a nice donor car for a convertible, $1,950. Bob, 910-350-0218, NC;... More
CADILLAC: 1962 60 Special sedan, a low mileage original car finished in black with tan interior. Hyman Ltd, 314-524-6000, MO; www.hymanltd.com... More


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This is a really great gift for any woman. It will be well received for the overall appearance of the package & the thoughtful contents. Especially the little touches that women appreciate like the candle, neck pillow, slippers etc. The Lavander theme is lovely and truly will make her think of and enjoy a relaxing time at the Spa. Good Value for the money !
Including shipping and everything, I think this gift set was an incredible value. It arrived 2 days after I purchased it for her, and she gushed over it.
This was a Valentine's Day gift for my girlfriend in another city (she had mentioned that she likes lavender-scented things). So i had it sent directly to her home. It arrived in plenty of time and she was quite pleased.
Since this was sent as a birthday gift out-of-state, I was unable to view it personally. However, the recipient said it was lovely. I've ordered from overstock.com many, many times and have never been disappointed.
It was a gifts for my mothers in law and she love it..
Purchased this a gift for Christmas. Was told that the scent, size, and options of everything in the basket was better than expected!
This was a gift... and she LOVED it! Excellent quality and items selection make this a unique gift basket.
Usually leaves our warehouse in 1 business day. *
Items must be returned in new or unused condition and contain all original materials included with the shipment. More details
FINAL SALE EXCLUSION: Items marked as FINAL SALE are not returnable unless the problem you experience is the result of our error.
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** Most Oversize orders are delivered within 1-4 weeks. Some orders may take 6 weeks to be delivered.


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Treffen / River Front Park
Datum:Friday, April 26th, 2013 (vor 10 monaten)
Zeit:4:00 pm
Treffpunkt:River Front Park
Adresse:100 W Riverside
BesprechenAnkündigung ansehen
kissedperfectionVor 11 Monaten
Who is all going?? I've never been to one before and I'm not sure if I should….
icanbakeyeahVor 10 Monaten
Last time I went to one of these I ended up in the home of a pot dealer lol
lizardsworld1984Vor 10 Monaten
how many people are going? what would we be doing?


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Halloween Candy - Novelty and Gifts
Gummi Skull on a Stick Assortment: 4-Piece Box
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Gummi Skull on a Stick Assortment: 4-Piece Box
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The fear of bones is commonly known as cartilogenophobia. If you don't have it, you might develop it once you hold these remarkably realistic gummy skull candies on a stick. Tear into the top of a cranium and keep gnawing away until you've devoured down to the lower jaw. Each box contains an assortment of fruit flavors distinguished by the colors blue, green, orange and red. Beware, the sweet gummy taste is addictive, and you just might develop a penchant for cannibalism while you consume one spooky head after another.
Unit Price = $7.50/piece.
Box contains 4 Assorted Gummi Skulls on a Stick.
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Shipping Weight ~ 3 lbs.
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Dec 7, 2012, 05:59 PM | #1 |
crusader kings 2 help
Does anyone know if it is possible to get CK2 out of its full screen mode and into the almost fullscreen mode where you can still access your desktop?
0 |
Dec 17, 2012, 03:07 PM | #2 |
Yes it is its a very simple change in a text file. I'll have to find the exact link etc please bare with me.
---------- The file is called settings.txt in your ~/Documents/Paradox Interactive/Crusader Kings II/ folder. The line fullScreen=yes controls if the game runs in full screen or windowed mode, for windowed mode change it to fullScreen=no. size={ x=1920 y=1200} defines the screen resolution. You can edit it manually as well, but it also can be changed in the in-game video options menu. |
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Here comes the Android tablet price plunge
April 8, 2011: 10:13 AM ETAcer's Iconia tablet looks as good as the XOOM on paper and is up for pre-order for $450.
If you've ever played with an Acer netbook, you'll know the computer maker isn't adept at turning out high end products. But the Taiwanese company makes a good mid-range product, and they do it with razor-thin margins. This strategy is part of the reason they canned their CEO Gianfranco Lanci last week, saying they wanted to be more like HTC and Apple (AAPL) rather than HP(HPQ).
But small margins allow Acer to bring to market a tablet that has most of the same components as the $600 Motorola (MMI) XOOM, including Nvidia Tegra 2 processor, 1280x800 display, 5 megapixel/2 megapixel cameras, USB2 and SD card storage expansion ...at a $150 discount.
On paper, this product is much better value than Motorola's offering, which some analysts estimate only sold 100,000 units as of April 1st.
Obviously, most tablet consumers will opt to pay $50 more and get the base model iPad instead.
However, the price war has just begun. Acer products at Best Buy don't tend to hold their prices well and look for this device to head toward the $399 range pretty quickly. Once the difference in price between iPad and Android is $100-$200, I'd expect more and more people to opt for Android –which is good for Google (GOOG).
The Iconia A500 Tab is available for pre-order at Best Buy for $450 and will take delivery on April 24th. I wouldn't expect any lines.
Netbook News fittingly has an unboxing of the Iconia A500 at a Burger King:
More on Fortune.com:


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What we learned from Dolphins' dress rehearsal in Tampa
Bittersweet is probably the word that describes it best. There was plenty to feel good about in the Dolphins' 13-17 loss at the hands of the Buccaneers on Saturday night.
Well, when I say plenty I'm mostly just referring to Chad Henne's performance. But he's a quarterback. A quarterback whose struggles prevented this team from threatening for a playoff spot a year ago. So, when Henne plays well there is a huge reason to be pleased.
But there was plenty of bad too. 76 yards worth of penalties bad. A grand total of 22 rushing yards in the entire game bad. The Tampa Bay running backs combining for 116 yards receiving bad.
Even with all the bad, though, the Dolphins were a Brandon Marshall fumble away from possibly taking a 13-3, maybe even a 17-3 lead into the half on a team that went 10-6 a year ago in the brutal NFC South.
And so the flip-flopping continues.
What should the fan base be feeling this Monday morning? Should they be thrilled that Chad Henne is seemingly coming around, or should the offensive line's nightmare game have Dolphin fans lining up to hit the panic button? Let's weigh the positives and negatives from a very indifferent night in Tampa.
Chad Henne may be a different quarterback: It may be the preseason, but it's looking more and more safe to assume that Chad Henne has finally turned the corner. I'm not saying he's going to be an elite quarterback in this league, but he surely looks like a quality one. A quarterback that is suddenly capable of putting this team on his back and actually winning games on his own. That's crucial because with the current state of the running game, he may have to.
But it's not just the big-time yardage and gaudy quarterback rating that has me thinking I'm looking at a completely different player. There were two plays that stood out to me against the Bucs in particular.
The first being an all out blitz from Tampa Bay that led to a simple quick out to Anthony Fasano for a 9-yard gain. But it's what Henne did before the play that excited me. He clearly recognizes the blitz and audibles at the line to a quick hitter to Fasano. That's the type of play that shows me he's finally taking command of this offense. Simple, yes, but still something we haven't seen from Chad in the past.
The other play was about a 6-yard completion to Clyde Gates on third and three. Henne's eyes are fixated to the right of the field from his drop back. Instead of forcing the pass into his first read, though, Henne looks left to find just enough room to fit a tight pass into Gates. Staring down receivers has been my major grip against Henne from day one. The sky is the limit if he's going to begin to go through his progressions.
And all of that isn't even mentioning the beautiful 60-yard touchdown strike to Brandon Marshall and another well-placed deep ball on a pass Clyde Gates should have probably reeled in. Henne has always had the arm strength; he's just never had the deep ball accuracy or the touch to utilize it consistently.
In the past two games Henne has completed 25 of 37 passes and has thrown for 369 yards and a touchdown with no interceptions. I don't want to make Henne's maturation official until he has similar success when it counts, but being optimistic isn't jumping the gun after what we've seen in back-to-back weeks.


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Writing Center Workshops
University of Wisconsin - Madison
Writing In-Class Essay Exams
Learn how to study for in-class essay exams and to write effective essays under time constraints.
Overview | Not sure what professors are looking for on an undergraduate in-class essay exam? This workshop will answer your questions and prepare you for writing college-level essays on examinations. We'll talk about studying for exams, planning your answers, starting your essays effectively, managing your time during the exams, and writing well-developed and coherent essays. |
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Duration |
1.25 hours |
Schedule for Spring 2014 |
Wednesday, 2/19, 4:00-5:15 (Sec. 1)


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Definition of polytene in English:
Line breaks: poly|tenePronunciation: /ˈpɒlɪtiːn
Genetics- Relating to or denoting a giant chromosome which is composed of many parallel copies of the genetic material, as found in Drosophila fruit flies where they are much used in genetic research.More example sentences
- The structures of rearrangements were defined by mitotic chromosome staining as well as by genetic and polytene chromosome analysis.
- Anopheline mosquitoes, like Drosophila, are renowned for the presence of polytene chromosomes and chromosomal inversions.
- It was mapped in Drosophila by polytene chromosome in situ to 3L heterochromatin.
1930s: from poly- 'many' + -tene (from Greek tainia 'band, ribbon') denoting stages of the first meiotic division.


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My First Gaming Build
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Denise Whiting, pictured in this 2010 photo, is preparing for this year's HonFest after a tumultuous year. (File photo by Jed Kirschbaum / June 5, 2012) |
- Hampden: Time to get hon-ey for HonFest, as we celebrate city's working women
- Denise Whiting
- Your pictures: Honfest
- Pictures: Honfest 2011
- Ghost of Hon-troversy
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1002 W 36th St, Baltimore, MD 21211, USA
Baltimore, MD 21211, USA
It's been a cathartic 12 months for Denise Whiting. She gave up her frowned-upon 'Hon' trademark, and apologized publicly for thinking that she could own a common term of endearment.
She cried on national television, as the celebrity chef Gordon Ramsay, of Fox-TV's 'Kitchen Nightmares,' ripped her restaurant, Café Hon, and her staff chided her as an overbearing boss.
She let Ramsay revamp the restaurant and its menu, softened her edges, laid low and rode out months of public rebuke.
And somehow, Whiting found time to plan HonFest, the regionally popular festival she founded in 1993. The 19th annual fest is June 9-10 on The Avenue in Hampden.
After a year of taking her lumps in the public eye, Whiting says, "We're back to business as usual."
In an interview May 31, the native Baltimorean, 53, pleaded to the public to "just let me run the restaurant and let me be creative and let me be a part of Hampden and let me be a part of Baltimore."
All the traditional enticements can be found at this year's festival, including Best Hon, Honette and Lil Hon contests, a full lineup of local bands, and acts such as The Fabulettes and The Singing Lucies.
New this year are the Mashed Potato Dance Contest on Sunday and the Glyndon Area Players performing songs from John Waters' Baltimore-inspired musical, "Hairspray," on Saturday.
Sponsors include Miller Light, Bacardi with its open-air drink lounge, M&T Bank, radio station 98 Rock, WBAL-TV, CBS Radio, Chick-fil-A, Long & Foster and Anderson Automotive.
"I think it's going to be the best HonFest ever," Whiting said.
Looking back
Last year, Whiting, a Kernewood resident, was in bad graces with Hampden merchants after she issued a decree, later withdrawn, that prohibited them from selling merchandise that might infringe upon her trademark.
A year ago this week, at a contentious meeting of the Hampden Village Merchants Association, there were questions about HonFest's impact on merchants and whether the festival was good for the business community.
Last November, Whiting dropped her trademark, and acknowledged, "It was never mine to have in the first place."
In an episode taped last fall that aired in February, the Ramsay show shined a national spotlight on Whiting. Kitchen Nightmares characterized the controversy as a public relations nightmare for her.
Employees told Whiting to her face she was a micro-manager with a big ego.
Whiting told Ramsay that Café Hon's business was off as much as 50 percent and that she feared for her life because of hate directed at her.
She also told the kitchen staff to "86" numerous menu items, as Ramsay watched aghast.
"I don't like cooking this menu," head chef Greg Jones told Ramsay.
The show described Café Hon as being "at war with its community," and Ramsay gave the restaurant bad marks, calling the meatloaf "mushy," and the fish and chips "greasy."


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Process and effect of planning and designing buildings, both in scientific (as a method of creating constructions) or art (as styles throughout ages) ways.
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How did the ancient engineers construct buildings that lasted thousands of years without modern science and mathematics?
The ancient engineers designed and built the Great Wall of China, Pyramids and Sphinx which lasted over thousands of years. At that point in time, there was no modern science and mathematics. How did ...


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You can also read manga online try the Bijo Juku manga!
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Program Snapshot
The Common Fund's Genotype-Tissue Expression (GTEx) program aims to study human gene expression and regulation in multiple tissues, providing valuable insights into the mechanisms of gene regulation and, in the future, its disease-related perturbations. Genetic variation between individuals will be examined for correlation with differences in gene expression level to identify regions of the genome that influence whether and how much a gene is expressed. The GTEx project includes the following initiatives:
- Novel Statistical Methods for Human Gene Expression Quantitative Trait Loci (eQTL) Analysis
- Laboratory, Data Analysis, and Coordinating Center (LDACC)
- caHUB Acquisition of Normal Tissues in Support of the GTEx Project
Program Highlights
The Genotype-Tissue Expression (GTEX) project Commentary is featured in Nature Genetics
The June 2013 issue of Nature Genetics highlights the GTEx project published by the GTEx Consortium.
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You and GTEx: Updated Informational Brochure
Visit the GTEx website for Donors and Families
For any questions, please contact Deborah Colantuoni at email@example.com
NEW! The Genotype-Tissue Expression Project (GTEx) Biospecimens Access Policy is a mechanism recently put in place to allow researchers access to tissues in the GTEx biobank. The policy and related forms can be found on the GTEx Portal. Click here for GTEx Portal. Click here for GTEx Sample Request Forms.
GTEx moves from pilot to scale up – The GTEx program is creating a comprehensive data and sample resource of genetic variation and gene expression profiles in multiple tissues from post-mortem donors. This resource will aid in the interpretation of Genome Wide Association Studies and help prioritize therapeutic targets by identifying those that affect gene expression.
See how many researchers are utilizing the GTEx data from mid-2012 to mid-2013
The GTEx (Genotype-Tissue Expression) Project. Correlations between genotype and tissue-specific gene expression levels will help identify regions of the genome that influence whether and how much a gene is expressed. GTEx will help researchers to understand inherited susceptibility to disease and will be a resource database and tissue bank for many studies in the future.


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Prices and availability are subject to change from the time and date that you print this page.
3/12/2014 5:57:12 AM. For Customer Service, please call
The Story
Starbucks brings home barista-quality coffee drinks with their state-of-the-art Verismo single-cup pod system. For those who prefer a less bold coffee, Veranda pods are a lighter-roasted blend of Latin American beans producing delicate, soft nuances of cocoa and lightly toasted nuts. Signature Verismo flavors are 100% Arabica beans, expertly roasted using varying times and temperatures to craft three roast profiles for every preference. Each coffee embodies its own distinct peak of aroma, acidity, body and flavor.
Part of the Starbucks® Verismo® Veranda Blend™ Coffee Pods Collection


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A Richmond judge has turned aside a lawsuit a Democratic senator filed challenging Republican plans to take
power in a 40-member Senate where Democrats and Republicans each old 20 seats.
Sen. Donald McEachin said a procedural ruling on his lawsuit in Richmond Circuit Court says that the issue is not ripe for the court to insert itself into the actions of a separate branch of state government.
McEachin, the plaintiff in the case, said the court ruled that the suit is premature because Republican Lt. Gov. Bill Bolling has not yet cast the decisive vote that Republicans claim gives them the right to rule.
McEachin said Friday morning that he and the Senate's Democrats have not yet decided about a possible appeal.


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BUFFALO, N.Y. — The Buffalo City Mission received a special delivery Wednesday from Just Pizza, but it wasn't covered in cheese and pepperoni.
With about two weeks to go before Thanksgiving, the pizzeria donated 100 twelve-pound turkeys.
This is the fifth year Just Pizza has teamed up with the City Mission. On Thanksgiving Day, the mission serves about 1,500 meals at its kitchen and home delivers more than 4,500 meals to Western New Yorkers.
"Thanksgiving is a great time for us to all think about how much we do have and to help the people that don't have much, so what anybody can do whether it's one turkey or a thousand turkeys, we'll be more than happy to receive them," said Stuart Harper, executive director of the Buffalo City Mission.
Harper says the mission needs 850 more turkeys to meet their goal.
Weather alert » More alerts
From the Weather On The Ones Forecast Center, The National Weather Service Has Issued A BLIZZARD WARNING for the following counties: Chautauqua, Erie (North), Erie (South), Genesee, Niagara, Orleans -- expires Thursday at 2:00AM. WINTER STORM WARNING for the following counties: Allegany, Cattaraugus -- expires Thursday at 2:00AM.


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Food, Wine & Nightlife See all
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Disneyland Resort Character Dining
Meet and dine with your favorite Disney characters at one of several select restaurants throughout the Disneyland® Resort in Anaheim! Eat with Mickey, Minnie ... Read more
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Marina Del Rey or Newport Beach, California
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Take in the sights of Los Angeles from the water, listen to relaxing music and unwind in the sun on this leisurely two-hour Sunday Champagne Brunch Cruise. Read more
Marina Del Rey or Newport Beach
Duration: 2 hours (approx.)
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Sunrise over the monuments and Capitol this morning in D.C.
- This was later once the sun was well up and behind the clouds. (Photo: Alex Liggitt/WJLA | Date: May. 10, 2011)
So I have wanted to go for a run on the Mall and take pictures during sunrise for a long time. I finally got a camera, a small Nikon s3000 that is 12MP and easy to carry. I also had a Camelback Rogue which not only kept me hydrated through the whole process but also acted as a backpack along the way. I was very happy with the outcome.
I started at my garage across the street from my office, headed down to the trail along the Potomac, and crossed the Memorial Bridge into D.C. which leads you directly to the Lincoln Memorial. The whole loop ended up being around 9 and a quarter miles, so if you're not a runner, it may be a good thing to own a bike.
It was a perfect morning for a run with temperatures in the 50s but it was a touch humid with dew points in the 50s, explaining the couple of sprinkles I saw while driving in at 5 a.m. I was a little worried about the amount of cloud cover there was, but there was enough clearing to the east for an ideal sunrise as it reflected off the clouds just about perfectly.


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2007 represents the second year of the eighth generation of Civics. Having taken Motor Trend's Car of the Year award in 2006 (as well as an award for North American Car of the Year given in Detroit that same year), the Civic did not change much for the following model year.
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Kris Humphries' Parents Are Divorcing!
By Radar Staff
A year after their son took his ill-fated walk down the aisle, Kris Humphries' parents, Debra and William are divorcing.
Debra filed in Minnesota earlier this… READ ON
By Radar Staff
A year after their son took his ill-fated walk down the aisle, Kris Humphries' parents, Debra and William are divorcing.
Debra filed in Minnesota earlier this… READ ON
By Radar Staff
Hollywood's hottest stars have been getting hot and heavy this summer!
From the sexiest singers and big screen bombshells to reality stars and Olympic athletes, there has… READ ON
Kim Kardashian And Kris Humphries: One Year After The Wedding… READ ON
By Radar Staff
Kim Kardashian showed off her stunning body in a retro-looking, floral bikini on Twitter Wednesday, and we've got the sexy shots for you on RadarOnline.com.
The 31-year-old… READ ON
By Jen Heger – Radar Assistant Managing Editor
During a status hearing in the ongoing bitter divorce battle between Kim Kardashian and Kris Humphries, the NBA star's lawyer told… READ ON
By Amber Goodhand – Radar News Editor
Jeremy Renner certainly isn't keeping up with the Kardashians.
The 41-year-old actor recently labeled the family as "ridiculous people with zero talent" –… READ ON
By Jen Heger – Radar Assistant Managing Editor
Kim Kardashian is growing increasingly impatient with the ongoing divorce proceedings with her estranged husband, Kris Humphries, because the reality TV… READ ON
By Radar Staff
She was ridiculed for calling time on her marriage to Kris Humphries just 72 days after their lavish wedding. But Kim Kardashian seems to be thinking… READ ON
By Jon Boon – Radar Reporter
Kim Kardashian's failed marriage to basketball star Kris Humphries has jinxed the Montecito, Calif. home where the nuptials were exchanged, RadarOnline.com is exclusively… READ ON
By Jen Heger – Radar Assistant Managing Editor
Who hates dogs? Kim Kardashian for one!
During the course of Kim's romance with her soon to-be-ex-husband, Kris Humphries' the reality… READ ON
By Radar Staff
Apparently some Hollywood stars don't know the Secret to avoiding underarm sweat stains!
It's hard not to break a sweat when you are one of the hottest… READ ON
Kim Kardashian and Kanye West topped off their trip to NYC last night by going to Broadway.
The pair took in the hit, The Book of Mormon, at the Eugene… READ ON
By Adriane Schwartz – Radar Reporter
Kim Kardashian is living in a celebrity fantasy world!
Kim's climb to fame began with her infamous sex tape, and now the reality… READ ON
By John Boon – Radar Staff
Kanye West has asked a private jeweler to make an engagement ring for Kim Kardashian by using diamonds and rubies from his late mom… READ ON
By Radar Staff
Kris Humphries will be joining the Nets in Brooklyn.
The celebrity-athlete Tuesday inked a 2-year, $24 million pact with the newly-relocated team.
"Kris has been a very… READ ON
Kris Humphries parties with friends in Miami Beach.… READ ON
By Alexis Tereszcuk – Radar Entertainment Editor
Kim Kardashian might be catching baby fever from her sister Kourtney, because RadarOnline.com has learned that she's been talking about having babies… READ ON
By Radar Staff
Kim Kardashian's ex Kris Humphries held court at a Miami get-together with plenty of bikini-clad beauties on Sunday and, RadarOnline.com has the pics for you.
The Brooklyn… READ ON
By Radar Staff
Kris Humphries is vehemently denying a report that Kelly Osbourne had him kicked out of a Hollywood nightclub.
"I never usually address garbage, but don't people think… READ ON
By Radar Staff
Kelly Osbourne, who's good friends with Kim Kardashian, had her fellow reality star's ex Kris Humphries reportedly kicked out of Beacher's Madhouse in Los Angeles Wednesday, RadarOnline.com… READ ON
By Alexis Tereszcuk – Radar Entertainment Editor
Myla Sinanaj is breaking her silence on her relationship with Kim Kardashian's husband and in a new interview she insists, that despite… READ ON


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Vincent C. GrayMayor Ask the Agency
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October 13, 2011
Story at a Glance
Media Contacts
(WASHINGTON, DC) – Mayor Vincent C. Gray today noted with disappointment that the U.S. Senate failed to pass the American Jobs Act proposed by President Obama.
"People across the nation are suffering because Congress refuses to act," said Mayor Gray. "Unemployment rates remain high in the District of Columbia, just like in others cities and towns. When will Congress provide the tools mayors and governors need to get our economy moving again?"
Mayor Gray noted that, during a recent meeting of the U.S Conference of Mayors in the District, mayors met with leaders of both parties -- including Senate Majority Leader Harry Reid, Senate Minority Leader Mitch McConnell, House Minority Leader Nancy Pelosi, and key members of the so-called "Super Committee" charged with deficit reduction.
The mayors have asked Congress to invest in transportation, water, housing, and energy infrastructure; to cut taxes for small businesses; to spur hiring through targeted tax incentives; and to modernize our schools, prevent teacher layoffs and keep our first responders on the job.