text:
Posted on April 16, 2011 at 8:30pm 0 Comments 0 Likes
I will never forget that summer for as long as I live. The summer where I found the love of my life, I was givein the thing that I needed to seek my life long dream then lost it, the summer I lost my best friend and my life changed completely.. It was the summer of 1973, in which I had my 17th birthday party, were I had all my closest friend's and family by my side.. Back then we didn't have all of the cool…
ContinuePosted on December 5, 2010 at 6:58pm 6 Comments 1 Like
As the Sun came up I woke up to the smell of mourning dew and mom's
lilac bush. I got out of bed and made my way down the stone stairs to find my
Mom and Dad already awake and reading Aunt Roselie's latest novel.
" Good Mourning Renesmee." My mother greeted me. " Good mourning.
How are you liking Aunt Rose's new novel?" I asked sitting down on the
Velvet couch and grabbing my Kindle. " Well I am finding it very moving
and very desciptive. ' As the water trickles…
Posted on December 5, 2010 at 9:48am 2 Comments 0 Likes
Dad got into his ' if you take one more step I'm going to kill you' stance. I rolled my eyes,
put down the Kindle, and ran outside iggnoring my parents ' stops or you don't know what
you are getting intos'. " Ok it has been 13 years and I still have not fallen for you so just
leave before this ends badly." I said trying to be as nice as possible. I walked to him and
motioned for him to go back to his normal annouging Jacob self. " Nessie I can't do
that! I…
ContinueHi Vampire Wolfy Girl welcome to Everything Vampire :[ a group where you can speak about any vampire movies, books and TV programs. Feel free to post photos, share your thoughts and make any discussion you want on vampires, as long as there's not already a thread on that same topic.
Now If you could just spare 5 mins of your time to Introduce yourself to our group, so you can get to know the rest of the members and so we can get to know you a little better. I hope you take part in our monthly quizes and have fun!
yeah, it's awsome. i mean i love dancing so being able to be on a show about a dance show ( wow thats kinda confusing ) it's.. im not even sure how to describe it..
thanks.. again :P
im fine just alittle tired and thanks :)
how are you?
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- 10 year CVD risk calculator ............
- — Corrected serum Na+ ....................
- (173)
- Corrected WBC in blood contaminated C...
- — JMP statistical discovery software .....
- (173)
- Jones criteria for diagnosis of rheum...
- — Probability of aortic rupture in blun...
- (173)
- Probability of pulmonary embolism ......
- — Zung self-rating depression scale ......
- (170)
- Journler. <Current version> 2006-, Macintosh OS onlyJournler is a software-based notebook information manager usable as an electronic laboratory notebook, among other applications. Macintosh only.
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- KChannelDB : Database
- Kinemage Analytical ToolKinemages are ""kinetic protein images"" that accompany many of the articles published in Protein Science. Kinemages are generated by the program MAGE from PDB files that have been processed using the program PREKIN.
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- Kt/V Dialysis dose Barth formula STAT!Ref
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- Kt/V Dialysis dose Jindal formula STAT!Ref
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- Kt/V Dialysis dose Lowrie formula STAT!Ref
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- miRBase sequences DatabaseRepository of miRNA sequences and annotations
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- Myocardial infarction probability (Goldman) Calculator
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- Negative predictive value of a test STAT!Ref
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- Normal range for body weight STAT!Ref
- NucleaRDB : DatabaseNucleaRDB stores curated sequences, mutation and ligand binding data for nuclear receptors.
- Nutricalc, [infant] nutrition calculator Calculator
- NVivo Product DescriptionRedwood Room (PC-8, only) Version 9.2 (Windows)
- Odds from probability STAT!Ref
- Odds ratio and relative risk STAT!Ref
- Oligo Analytical Tool, CMGM/PMGM registration requiredThe Oligo program is likely the best tool for creating oligonucleotides ("oligos"), i.e., determining the sequence of oligos so that they can be synthesized and used in e.g., polymerase chain reaction (PCR).
- Oncomine research edition DatabaseA repository of transcriptome profiles used for data-mining and visualization for biomarker and therapeutic target discovery and evaluation.
- Online Mendelian inheritance in man DatabaseA catalog of essays reviewing human genetic traits that follow classical Mendelian inheritance patterns. Whenever available information permits, each entry consists of six parts: (1) a preferred designation, and frequently used synonyms, (2) a brief description of the phenotype(s), (3) the nature of the basic defect, (4) a résumé of pertinent genetic information including mapping and molecular genetic details, (5) an exhaustive list and description of known allelic variants, and (6) key references. An attempt has been made to select references that are up to date and/or particularly useful discussions of the genetics involved. The catalog provides a bibliographic guide. OMIM is a full text database searchable by the IRX (tm) software developed by the National Library of Medicine. Access to the database is provided as a service to biomedical professionals by the Johns Hopkins University School of Medicine under the sponsorship of the National Institutes of Health and the Department of Energy.A database that features catalogs of autosomal dominant, autosomal recessive, x-linked, y-linked, and mitochondrial phenotypes. Includes information on human genes and genetic disorders.
- Open REGulatory ANNOtation database (ORegAnno) Database, Login requiredThe ORegAnno database stores curated data derived from scientific literature for known gene regulatory elements.
- Opioid medication dose conversions STAT!Ref
- Oracle SQL developer WebsiteFree, Multi-platform (Win/Mac/UNIX/Linux) graphical tool for database development, supported by Oracle Corp. Suitable for Oracle, Sybase, MySQL and many other relational database managers.
- ORegAnno Database, Login requiredThe ORegAnno database stores curated data derived from scientific literature for known gene regulatory elements.
- Osmolality Estimator (serum) STAT!Ref
- Osmolar clearance STAT!Ref
- Oswestry low back pain disability questionnaire Calculator, Use Internet Explorer only
- Ottawa ankle rules Calculator
- Ottawa knee rules Calculator
- Oxygenation index Calculator
- Oxygenation index (OI) STAT!Ref
- Paediatric coma scale (Simpson & Reilly) Calculator
- Pajek WebsiteNetwork analysis software, suitable for studying networks composed of widely different components: people, molecules, etc.
- Pancreatitis prognosis criteria STAT!Ref
- PantherDB Database
- Papers, your personal library of science 2006-, Macintosh OS onlyPapers is personal literature manager that enables you to search, download, archive, and organize all your articles, including PDFs, within a single application. Macintosh only.
- Partek Genomics suite Analytical Tool, SUNet ID login and CMGM/PMGM computer account are required for web usage of this software"Comprehensive suite of statistics and interactive data visualization designed to reliably extract biological signals from noisy data; can be applied to a variety of genomic data sets, such as gene expression data, exon data, copy number data, mapping data, tiling data, and SNP data. "
- Pathway builder Analytical ToolA quick and easy tool for drawing signal transduction pathways. Contains pre-made pathway templates and illustration items, as well as all pathway items such as membranes, protein/receptor shapes, organelles, etc. have been pre-made.
- PathwayStudio Analytical Tool, Login requiredAnalysis software intended to facilitate the interpretation of experimental results in the context of pathways, gene regulation networks and protein interaction maps.
- PDB DatabasePDB is the primary repository of biomolecular structures. It is cross-referenced with many of the major public Life Sciences databases (e.g., OMIM, GO, and several others).
- Peak expiratory flow calculator Calculator
- Peak expiratory flow prediction STAT!Ref
- Pediatric dosing calculator Calculator
- Pediatric fluids and electrolyte therapy Calculator
- Pediatric trauma score Calculator, Use Internet Explorer only
- Penetrating abdominal trauma index Calculator, Use Internet Explorer only
- Perl Analytical Tool
- PharmGKB Stanf UnivLogin Stanf UnivPharmGKB is an integrated resource about how variation in human genes leads to variation in our response to drugs.
- PhenomicDB DatabasePhenomicDB merges public genotype/phenotype data from a wide range of model-organisms and Homo sapiens. It is unique in enabling ontological querying, i.e., querying using conceptsrather than key words. Stated another way, PhenomcDB is an integrated meta search-engine for phenotypes.
- Phrap Download softwareA Linux/UNIX program for assembling shotgun DNA sequence data.
- Phred Download softwarePhred is Linux/UNIX software reads DNA sequencing trace files, calls bases, and assigns a quality value to each called base.
- Phylogenetic analysis Video
- PhysioNet WebsiteAn on-line forum for dissemination and exchange of recorded biomedical signals and open-source software for analyzing them, by providing facilities for cooperative analysis of data and evaluation of proposed new algorithms.
- PICU PalmA calculator for pediatric ICU. It calculates defibrillation, vasoactive infusions, reanimation and intubation drugs by simply entering the weight of the patient.
- PIM (Pediatric Index of Mortality) Calculator
- Pittsburgh knee rule Calculator
- PlasmoDB Database, Login requiredProvides genomic and proteomic data for different species of the parasitic eukaryote Plasmodium, as well as its own analytical functions.
- Pneumonia severity index calculator Web versionDownload PDA version PalmDownload PDA version Pocket PC
- Pneumothorax degree of collapse STAT!Ref
- Pocket Pearls Palm
- PolyPhred Download softwareA Linux/UNIX program that compares fluorescence-based sequences across traces obtained from e.g. different individuals to identify heterozygous sites for single nucleotide substitutions.
- Positive predictive value of a test STAT!Ref
- Predicting strep pharyngitis Calculator
- PredictProtein server Analytical Tool
- Pregnancy calculator Calculator
- PrionDB : Database
- PRISM (Pediatric Risk of Mortality) score Calculator
- Probability from odds STAT!Ref
- Probability of acute bacterial sinusitis Calculator
- 10 year CVD risk calculator ............
- — Corrected serum Na+ ....................
- (173)
- Corrected WBC in blood contaminated C...
- — JMP statistical discovery software .....
- (173)
- Jones criteria for diagnosis of rheum...
- — Probability of aortic rupture in blun...
- (173)
- Probability of pulmonary embolism ......
- — Zung self-rating depression scale ......
- (170)
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subset: commoncrawl


text:
Last updated: Mon Mar 10 22:52:16 EDT 2014
CVE Publication rate: 14.3
NVD provides four mailing lists to the public. For information and subscription instructions please visit NVD Mailing Lists
Vulnerability Workload Index: 6.34
pngrtran.c in libpng before 1.0.29 and 1.2.x before 1.2.21 use (1) logical instead of bitwise operations and (2) incorrect comparisons, which might allow remote attackers to cause a denial of service (crash) via a crafted PNG image.
By selecting these links, you will be leaving NIST webspace. We have provided these links to other web sites because they may have information that would be of interest to you. No inferences should be drawn on account of other sites being referenced, or not, from this page. There may be other web sites that are more appropriate for your purpose. NIST does not necessarily endorse the views expressed, or concur with the facts presented on these sites. Further, NIST does not endorse any commercial products that may be mentioned on these sites. Please address comments about this page to email@example.com.
Configuration 1 |
* cpe:/a:libpng:libpng:1.0.28 and previous versions |
* cpe:/a:libpng:libpng:1.2.20 and previous versions |


text:
Dec 8, 2012 | Posted by: roboblogger | Full story: WDIO
Judged: 1 1 1 |
Saint Paul, MN |
Judged: 1 1 1 |
Judged: 1 1 1 |
"The one and only Smart Liberal" Since: Aug 12 3,858 Former MN Tax Payer |
YES WE CAN! Just what the State of MN needs is another light rail boondoggle that will never pay for itself. The train has failed more than once btwn Mpls and Duluth. What makes anyone think that it will succeed this time? Oh, yeah. I forgot. We can do it with subsidies where the Feds give free money to MN to build this thing. I think they fund 50% of it so it is very cheap for the citizens of MN. Something like $4 billion the State pays and $4 billion the Feds pay. Now, I wonder where the Fed gets their $4 billion to give to Minnesota for FREE? |
Since: Apr 08 6,703 Twin Cities |
If I understood the article correctly, the light rail would be mainly for the benefit of students going home for the weekends and it takes about the same amount of time as travelling by car. Did I get that right? While I love the idea of mass transit, this seems like an unnecessary expenditure. If the end game is reducing the carbon footprint of 'thousands' of students returning home to the Cities each weekend, wouldn't it just be cheaper to sponsor greyhound buses for that purpose? I'm trying to picture a light rail system opening up the North Shore and the Iron Range for expansion and growth, but I'm just not seeing it.
Judged: 1 1 No subsidy for the Commuter, 100% of the cost of the ride paid by the "User", not by her neighbor. What a radical concept!....Pay your own way. |
If America does not reverse the Collectivization that is the mantra of the Ignorant Left, a Horse and Buggy will become a luxury item after you Sheeple destroy the country with your ignorance and narcissism! |
Saint Paul, MN |
Judged: 1 1 Consider the North Star rail line. You know the one serving the norh suburbs that can't get riders even if they give free rides. Oh they blame the Twins bad season for failed ridership, does that mean the North Star is a Twins relatd product. All we need is more BILLIONS supporting the failed Twins. All the need is a new stadium Who can a Libertard controlled government be controlled? There is NO DOUBT if a rail line is built to Duluth it will be a complete failure just like NorthStar. NorthStar only cost $325,000,000 or 1/3 of a BILLION. But it created JOBS!! Duluth's population has been going down it's a hell whole. Ask someone who has lived there, it's a industrial town with visiting sailors messing it up and throw in a couple of DFL perverts and walla Duluth. There is absolutly NO HOPE for controlled spending with DFL in charge of Minnesota. Bend over and apply KY because the tax man is comming!!! |
Saint Paul, MN |
A new concept for cars is needed. Construct them with hitches front and rear and hook them togeather making a long train and pull them with a semi tractor. Semis get like 10 MPG so if 10 cars were towed by one semi the MPG would be 100 MPG. 10 2,000 pound cars is only 20,000 pounds so a semi could tow a car train of 40 cars yeilding an effective per vehicle MPG of 400 MPG. Allowing drivers to sit in comfort/security of their own vehicles, don't know about heat/AC, minor implementation details. I can't imagine the creative activities a bunch of college punks could come up with, crawling from car to car spreading STDs etc. |
Since: Sep 08 10,900 Neon City Oh. |
"The one and only Smart Liberal" Since: Aug 12 3,858 Former MN Tax Payer |
Judged: 1 1 if the market will support it, great. Do it. But do it with private dollars, not tax dollars. |
Judged: 1 1 |
Since: Sep 11 7,306 |
Slewpid people don't know the difference between government subsidized transportation that does not pay off and NASA. They also don't realize how many every day marvels are byproducts of space research such as velcro, carbon conposites, adhesives, etc etc etc.
Transportation is important and you're a moron...My NASA point is we subsidize public works all the time, try to be a real man and NOT TWIST WORDS....
Judged: 1 1 1 |
You lie, try another moniker...
Where is my c-note biggie schmalls? |
Where is the wager ??? Poor child, try as you might, you're a moron.
Since: Apr 08 6,703 Twin Cities |
Well, now that's some creative thinking! I wonder if the schools up north are offering any kind of carpool options to help the kids get back home on the weekends? Or better yet, are the students themselves organizing their own carpools? |
Since: Sep 11 7,306 |
As expected, Slwepid missed my point that you can't compare the ROI from NASA with a boondoggle train that has already failed a number of times and will likely become a big "party barge" for a bunch of college students. If they want to drive to the cities every weekend let them carpool.
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Sonic Expanse
Kimber Kable was more than happy to show off the four latest additions to its very full line of cables. First came the 12TC Teflon-insulated speaker cables, which use 24 conductors. Terminated with WBT Nextgen, an 8' pair of 12TC costs $854. Next there's the Cadence Subwoofer cable, which costs $175 for 1 meter with the best terminations Kimber supplies. Finally, complementing Kimber's HD19 1.3 cable, which costs $239 for 4 meters are the new HD09 1.3 (5 meters for $159) and HD29 1.3 (5 meters for $557). Other lengths are, of course, available. The display in the Venetian may have been static, but the very live demo Kimber Kable was conducting simultaneously at The Alexis Park was reportedly producing great sound.
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text:
Woman, 88, robbed in home invasion
Assailant drops cash while fleeing home
Published 6:58 PM EDT Oct 07, 2012
An 88-year-old woman was confronted by a masked man during a home invasion Saturday night in Rockingham County.
Authorities with the Rockingham County Sheriff's Office said Virginia Sharp was inside her home on Ellisboro Road about 11 p.m. when the man cut the phone lines to her home and kicked in a back door.
Investigators said the assailant, who was described as a white man with a medium build, confronted Sharp and demanded money. They said she gave him about $100, much of which was dropped in her yard as he fled.
Sharp was not injured during the robbery.
Anyone with information about the case should contact the Rockingham County Sheriff's Office at 336-634-3232 or Crime Stoppers at 336-349-9683.


text:
90 percent of businesses say they have fallen victim to a cyber security breach at least once in the past 12 months. That percentage isn't based on a small number either: 583 US companies participated in the questionnaire.
The data comes from a new survey of US IT and IT Security professionals, conducted independently by Ponemon Institute and sponsored by Juniper Networks. You can check out the 25-page report here: Perceptions About Network Security (PDF).
The 90 percent number is just for one breach; organizations today are experiencing multiple breaches. In fact, more than half (59 percent) of respondents cited two or more breaches in the past 12 months. Companies indicate that security breaches have cost them a least half a million dollars to address in terms of cash outlays, business disruption, revenue losses, internal labor, overhead, and other expenses. Most respondents (59 percent) report that the most severe consequence of any breach was the theft of information assets followed by business disruption.
It gets worse. Security attacks are on the rise, according to the data provided by these companies. 43 percent of respondents indicating there has been a significant increase in the frequency of cyber attacks during the past 12 months and 77 percent say these attacks have become more severe or difficult to detect/contain. As a result of these multiple breaches, more than one-third (34 percent) of respondents say they have low confidence in the ability of their organization's IT infrastructure to prevent a network security breach in the future.
It's also worth noting that only 11 percent of respondents believe they know the source of all their network's security breaches. Unsurprisingly, employee mobile devices and laptops are seen as the most likely entry point from which serious cyber attacks are unleashed against a company.
"Our survey research provides evidence that many organizations are ill-equipped to prevent cyber attacks against networks and enterprise systems," Dr. Larry Ponemon, chairman and founder of the Ponemon Institute, said in a statement. "This study suggests conventional network security methods need to improve in order to curtail internal and external threats."
"The size and complexity of today's security threats continue to intensify leaving organizations and governments vulnerable to cyber attacks," Mark Bauhaus, executive vice president and general manager of Juniper Networks Device and Network Services, said in a statement. "Business leaders need to consider a more aggressive, systemic security approach—implementing end-to-end comprehensive protection at all points in the network to help mitigate risk."
User Comments: 10
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Those are some incredible statistics. And I believe them. Where I work (a government agency), there has been an attempt to breach our security a number of times.
I saw an email from EA this morning that their Never Winter Night forum server got hack. Told Matt about incase he wanted to use it for news but I guess not XD or he hasn't been on yet...
stewi0001 said:
I saw an email from EA this morning that their Never Winter Night forum server got hack. Told Matt about incase he wanted to use it for news but I guess not XD or he hasn't been on yet...
Ya, seems like one of their old forum servers got compromised and EA isn't taking any chances resetting everyones password.
TomSEA said:
Those are some incredible statistics. And I believe them. Where I work (a government agency), there has been an attempt to breach our security a number of times.
Although your statement breathes grams of credibility for the simple fact that you work for the govt, I believe you. Someone I pissed off tried to hack into my yahoo acount 7 years ago. It's also cute how close you put "incredible" to "believe".
(There's lies, big lies, and then there's statistics)
PS: those "statistics" shouldn't come as such a big surprise to someone working for the govt, should they?
To anyone who works in network security, you're right. These statistics aren't surprising in the least. Especially for folks working in high-value environments (i.e. large corporations, governments, etc.).
Considering that both high-speed internet and computers have become standard (if not necessary) household items over the last 12 years, I'm surprised these numbers aren't larger. As more people get connected and become tech savvy globally the number and complexity of these breaches is only going to grow. There's going to be a lot of money to be made in cyber security over the next decade.
I wouldn't say more people are becoming tech savy for say. I would say with such a vast increase of users with the last 5+ years, the world wide web user base has expanded to where tech savy and not tech savy are far from the two types. What is tech savy? Seems the difinition is bluried these days. Computers becoming more simple, companies requiring a vastly large amount out of IT staff, ,less knowledgeable individuals within the IT field, along with companies making the employment process for such IT Techs are only some of matters that make that article perfectly true.
Boils down to Companys need to step up their policys over all in regards to IT Staff and Budget.
I will say that 90% of the companies are the ones that know that they got hacked -- the other 10% got hacked as well but haven't found out about it yet...
stewi0001 said:
I saw an email from EA this morning that their Never Winter Night forum server got hack. Told Matt about incase he wanted to use it for news but I guess not XD or he hasn't been on yet...
yea they told me they also lost my CD key, I was like ahh great now my games CD key gonna appear on torrents and my CD key gonna be blacklisted
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Spurs news and notes: R.C. on Duncan's injury, Spurs are boneheads, and more
• It's that time San Antonio Spurs fans. Playoff tickets will be available this Saturday for the opening round:
Spurs Playoff tickets for Round 1, games A & B range in price from $10 to $295, including lower-level seats starting at $88. Dates, times and opponent for the Spurs first round NBA Playoff schedule will be announced at a later date.
Playoff tickets can be purchased at all Ticketmaster Ticket Center locations, including select H-E-B locations, charge by phone at (210) 225-TEAM or online at spurs.com or ticketmaster.com.
Playoff tickets can also be purchased at the AT&T Center Southeast Box Office Monday through Friday from 10 a.m. until 6 p.m. and weekend event days only, beginning at 10 a.m.
• See what R.C. Buford had to say about Tim Duncan's injury at Spurs.com.
• Express News' Tim Griffin talks about the upcoming games for the Spurs.
• Spurs head coach Gregg Popovich on Steve Novak's inbound pass that sailed out of bounds in the loss to the Portland Trail Blazers:
Asked about the play, Spurs coach Gregg Popovich offered: "Yeah, we wanted to throw it straight out of bounds without anybody touching it." (nba.com)
• Speaking of the Spurs loss to the Blazers, woai.com asks who is the bigger bonehead -- the Spurs for losing to the Blazers or former NFL player Lawrence Taylor?
• RedsArmy.com watches every move the Spurs make. Celtics fans know the Spurs might give their team some problems this Thursday if Duncan and Manu Ginobili return to action.
Hit the jump to read about a former Spur making it in the NBA, an injured Celtic to make his return versus the Spurs, and more.


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Home / LSA Students / Academics & Requirements / Majors & Minors / Residential College (RC) /
Creative Writing and Literature Major
May be elected as a departmental major
Not open to those electing the minor in Writing or the minor in Creative Writing (effective Fall 2011)
The Residential College's Creative Writing and Literature Major combines the sustained, disciplined practice of writing with the serious study of literature. The main goal of the program is to help students develop their creative abilities through a continuous, interrelated cycle of writing, rewriting, and literary analysis. Creative writing courses are taught as workshops and tutorials in which students work individually with faculty members. Students are required to take courses in literature in order to understand better the art of writing.
Students wishing to pursue a sustained practice in creative writing take a combination of writing courses in a selected genre and literature courses, distributed as follows:
- A minimum of four creative writing classes, three at the upper level (300 and above), mixing seminars (RCHUMS 220, 221, 222, 242, 320, 321, 322) and tutorials (RCHUMS 325, 326, 425, 426)
- A minimum of five upper level (300 and above) literature courses at least one of which must be ancient (RCHUMS 309, CLCIV 390, ENGLISH 401) or medieval (RCHUMS 310, ENGLISH 370) literature.


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New Release: The Funk Ark – 'From The Rooftops' + MP3
July 26th, 2011
DC-based world funk ensemble The Funk Ark has just released their debut album, From The Rooftops, and might we say that it's quite uplifting. Drawing inspiration from African and Latin funk music of the 60's and 70's, The Funk Ark oozes a soulful vintage sound channeling Afrobeat and big band funk.
Keyboardist and songwriter Will Rast, well known for his work with the likes of Thievery Corporation and Ocote Soul Sounds, fronts the eight-piece band. The man is bringing it and taking listeners on a global funk journey that will have you melting into the dancefloor.
Catch The Funk Ark on tour this and next month!
The Funk Ark - "El Beasto" [MP3]
Purchase From The Rooftops on iTunes | Amazon


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Each chapter features a conversational lesson and features multiple illustrations before moving on to practice exercises and a problem set-both of which include questions based on problems found in the CLEP and SAT II math tests. Function basics are covered before moving on to polynomial, rational, exponential and logarithmic, radical, power and trigonometric functions; vectors, polar coordinates, systems, matrices, determinants, analytic geometry, sequences, probability, statistics and calculus.
This Kit Contains:
System Requirements:
For Windows:
For Mac


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Nora Bannister is a bestselling mystery novelist who buys run-down houses in LA. While her business partners turn the house into a showpiece, Nora makes it the scene of a grisly murder in her House To Die For series. As soon as the new book goes on sale, so does the house — and the bidding frenzy begins. It seems a lot of people are willing to pay a lot of money to live in a real house where a fictional character has died a violent death.
Just before Nora's latest book hits the market, one of her house-flipping partners is murdered. LAPD Detectives Mike Lomax and Terry Biggs are assigned the case, but this one is a hot potato – the dead woman is also the wife of one of their fellow cops. As Mike and Terry dig into the victim's private life, more bodies turn up . . .
Is someone stalking the house flippers or is the murderer after cops' wives? Either way, Mike and Terry have to track down the killer before he murders his next logical target — Marilyn Biggs, Terry's wife.
Sign up to receive information about new books, author events, and special offers.
"If you haven't read Marshall Karp yet, start with Flipping Out. Start today. This mystery is right up there with the best of Janet Evanovich and Carl Hiassen. Yep, it's that suspenseful, that funny."--James Patterson
"You're going to love meeting Mike Lomax and Terry Biggs, a pair of hip homicide detectives with the LAPD; unless, of course, you're the perp. Smart, funny and intuitive, Lomax and Briggs glide through the overlit shoals of Los Angeles like sharks through ginger ale. As up to the minute as they are intensely observant, the guys, this time, prowl the golden muck of the Los Angeles real estate bubble to fine effect; an exhilarating read."--Donald E. Westlake, author of Bad News and Watch Your Back!
"Marshall Karp's mordant humor and knack for crackling dialogue are on fine display in FLIPPING OUT. Now that the housing market has tanked and the rest of the economy with it, there's guilty pleasure in reading a book where greedy real-estate speculation would seem to provide a motive for murder. Karp gets everything right, from cop-shop talk to bedroom banter, with bite-sized chapters fueling the pace."--Bob Morris, author of Bahamarama and A Deadly Silver Sea
"Read this book and you'll be grinning the whole way through. Marshall Karp knows how to keep a story running full speed full time. This one's a blast."--Michael Connelly
"Blending the gritty realism of a Joseph Wambaugh police procedural with the sardonic humor of Janet Evanovich, Karp delivers a treat that's not only laugh-out-loud funny but also remarkably suspenseful."--Publishers Weekly
An award-winning former advertising executive, MARSHALL KARP is a playwright, a screenwriter, and has written and produced numerous TV shows. Having paid his dues in Hollywood, he began killing the people he used to work with. His first novel, The Rabbit Factory, set in a Disneyesque studio, introduces LAPD Detectives Mike Lomax and Terry Biggs. In Bloodthirsty, they returned when some of the most powerful and hated men in show business turn up dead. Marshall is at work on the further adventures of Lomax & Biggs deep in the woods of New York's Hudson Valley, where he subsists on nuts, berries, and reader feedback. If you'd like to be a character in Marshall's next book, visit his site at www.lomaxandbiggs.com. The link that lets you enter the contest isn't that easy to find, but then, you like a good mystery, don't you?
Marshall Karp


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No. 495993
Durable closed-coated aluminum oxide incorpates an anti-static coating, leading to lower clogging, faster results, and longer abrasive life.
No. 499105
Finish Faster - Rubin 2 is designed to quickly shed wood fibers, eliminating clogging so the abrasive stays sharp, leading to a 30% faster removal rate.
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Durable open-coated aluminum oxide cuts, rather than grinds material surface, leading to faster material removal and a cleaner finish.
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Compatible with Festool ES 125, ETS 125, Rotex RO 125 and other 5-inch sanders.
No. 497150
No. 499102
No. 499093
No. 499108


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A free world-class appliance repair website for everyone.Connect with appliance repair technicians from the U.S. and Canada.Download free service manuals, wiring diagrams, tech sheets and more.
Heating element resistance 8.5 ohmsThermistor resistance 10.2k ohmsThermal cutoff 0 ohmsThermal fuse 0 ohms
I just did this repair today. My question is when I took the back off, a clip fell out and I have no idea where it goes. Any help?
Started by AJ
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text: Welcome Waco Habitat for Humanity is an ecumenical Christian housing ministry helping to eliminate substandard and poverty housing in Waco, TX. Since 1986, Waco Habitat for Humanity has built over 150 simple, decent, affordable homes in partnership with people in need. Having begun supplementing its new home construction program in recent years, Waco Habitat has served another 225 families through Critical Home Repairs and Ramps & Rails.Upcoming EventsWaco Habitat BlogBrick & Block pallets - 25% OFF! Promo has ended--thanks for saving with us!Posted on February 18th, 2014 by Waco ReStore Waco ReStore Project Facebook Post Contest--Thanks to all who participated!Posted on January 22nd, 2014 by Waco ReStore Help us get to 2,000 Likes on facebook! Save 20%! This promo has ended.Thanks!Posted on January 8th, 2014 by Waco ReStore


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Writers on the Range
A remembrance of Jo Anne Garrett
A remarkable Western activist.
by Abby Johnson, Bob Fulkerson and Patrick O'Driscoll , Nov 28, 2013 -
Oil shale never stays down long
The implications of Shell Oil's abandonment of its oil shale project in western Colorado.
by Steve Andrews and Matthew Garrington, Nov 26, 2013 -
On being away from my primal landscape
It was no secret I didn't want to leave the West.
by Charles Finn, Nov 21, 2013 -
Health care reform: A chronic national malady
Will we ever get it right?
by Travis Kelly, Nov 20, 2013 -
We need younger hunters
Without new hunters to carry on conservation traditions, wild game and habitat will suffer.
by Andrew Gulliford, Nov 19, 2013 -
Will there ever be a 51st state?
When we work together, we work to form a more perfect union.
by Peter Laufer, Nov 14, 2013 -
Tree-sitters have changed since the 80s
The protest tradition continues with new demographics.
by Robert Leo Heilman, Nov 12, 2013 -
Wolf populations should be assessed by packs, not individuals
The government's decision to delist gray wolves is flawed.
by Marybeth Holleman, Nov 07, 2013 -
A uranium mining proposal threatens water supplies
This South Dakota project claims technology will trump nature.
by Ken Steinken, Nov 05, 2013 -
Boy Scout leadership needs higher standards
Do Boy Scouts fret too much about gays and not enough about some of their ill-trained youth leaders?
by Casey O'Malley, Oct 31, 2013


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World Series Quotations
Related Quotes Baseball Sports Effort Money Autumn
It's a funny kind of month, October. For the really keen... fan it's when you discover that your wife left you in May. ~Denis Norden (actually, it's a quote about cricket) It's hard to win a pennant, but it's harder losing one. ~Chuck Tanner When we played, World Series checks meant something. Now all they do is screw up your taxes. ~Don Drysdale, 1978 What does a mama bear on the pill have in common with the World Series? No cubs. ~Harry Caray If the World Series runs until election day, the networks will run the first one-half inning and project the winner. ~Lindsey Nelson There are three things in my life which I really love: God, my family, and baseball. The only problem - once baseball season starts, I change the order around a bit. ~Al Gallagher, 1971 People ask me what I do in winter when there's no baseball. I'll tell you what I do. I stare out the window and wait for spring. ~Rogers Hornsby You see, you spend a good piece of your life gripping a baseball, and in the end it turns out that it was the other way around all the time. ~Jim Bouton, Ball Four, 1970 A hot dog at the ball park is better than steak at the Ritz. ~Humphrey Bogart With those who don't give a damn about baseball, I can only sympathize. I do not resent them. I am even willing to concede that many of them are physically clean, good to their mothers and in favor of world peace. But while the game is on, I can't think of anything to say to them. ~Art Hill Baseball is a harbor, a seclusion from failure that really matters, a playful utopia in which virtuosity can be savored to the third decimal place of a batting average. ~Mark Kramer What is both surprising and delightful is that spectators are allowed, and even expected, to join in the vocal part of the game.... There is no reason why the field should not try to put the batsman off his stroke at the critical moment by neatly timed disparagements of his wife's fidelity and his mother's respectability. ~George Bernard Shaw I'm convinced that every boy, in his heart, would rather steal second base than an automobile. ~Tom Clark You gotta be a man to play baseball for a living, but you gotta have a lot of little boy in you, too. ~Roy Campanella I see great things in baseball. It's our game - the American game. It will take our people out-of-doors, fill them with oxygen, give them a larger physical stoicism. Tend to relieve us from being a nervous, dyspeptic set. Repair these losses, and be a blessing to us. ~Walt Whitman Baseball is a game where a curve is an optical illusion, a screwball can be a pitch or a person, stealing is legal and you can spit anywhere you like except in the umpire's eye or on the ball. ~Jim Murray Good pitching will beat good hitting any time, and vice versa. ~Bob Veale, 1966 Baseball players are smarter than football players. How often do you see a baseball team penalized for too many men on the field? ~Jim Bouton, 1988 Say this much for big league baseball - it is beyond question the greatest conversation piece ever invented in America. ~Bruce Catton The charm of baseball is that, dull as it may be on the field, it is endlessly fascinating as a rehash. ~Jim Murray It breaks your heart. It is designed to break your heart. The game begins in spring, when everything else begins again, and it blossoms in the summer, filling the afternoons and evenings, and then as soon as the chill rains come, it stops and leaves you to face the fall alone. ~A. Bartlett Giamatti, "The Green Fields of the Mind," Yale Alumni Magazine, November 1977 Baseball is almost the only orderly thing in a very unorderly world. If you get three strikes, even the best lawyer in the world can't get you off. ~Bill Veeck Baseball is the only place in life where a sacrifice is really appreciated. ~Author Unknown Ideally, the umpire should combine the integrity of a Supreme Court judge, the physical agility of an acrobat, the endurance of Job and the imperturbability of Buddha. ~"The Villains in Blue," Time magazine, 25 August 1961 I've come to the conclusion that the two most important things in life are good friends and a good bullpen. ~Bob Lemon, 1981 You can't sit on a lead and run a few plays into the line and just kill the clock. You've got to throw the ball over the goddamn plate and give the other man his chance. That's why baseball is the greatest game of them all. ~Earl Weaver It's no coincidence that female interest in the sport of baseball has increased greatly since the ballplayers swapped those wonderful old-time baggy flannel uniforms for leotards. ~Mike Royko Baseball is an allegorical play about America, a poetic, complex, and subtle play of courage, fear, good luck, mistakes, patience about fate, and sober self-esteem. ~Saul Steinberg The pitcher has to find out if the hitter is timid. And if the hitter is timid, he has to remind the hitter he's timid. ~Don Drysdale, quoted in New York Times, 9 July 1979 It ain't like football. You can't make up no trick plays. ~Yogi Berra A baseball fan has the digestive apparatus of a billy goat. He can, and does, devour any set of diamond statistics with insatiable appetite and then nuzzles hungrily for more. ~Arthur Daley Baseball is not necessarily an obsessive-compulsive disorder, like washing your hands 100 times a day, but it's beginning to seem that way. We're reaching the point where you can be a truly dedicated, state-of-the-art fan or you can have a life. Take your pick. ~Thomas Boswell, Washington Post, 13 April 1990 This is a game to be savored, not gulped. There's time to discuss everything between pitches or between innings. ~Bill Veeck A critic once characterized baseball as six minutes of action crammed into two-and-one-half hours. ~Ray Fitzgerald, in Boston Glove, 1970 I don't know why people like the home run so much. A home run is over as soon as it starts.... The triple is the most exciting play of the game. A triple is like meeting a woman who excites you, spending the evening talking and getting more excited, then taking her home. It drags on and on. You're never sure how it's going to turn out. ~George Foster, 1978 Baseball is a game dominated by vital ghosts; it's a fraternity, like no other we have of the active and the no longer so, the living and the dead. ~Richard Gilman The other sports are just sports. Baseball is a love. ~Bryant Gumbel, 1981 There have been only two geniuses in the world. Willie Mays and Willie Shakespeare. ~Tallulah Bankhead Baseball fans love numbers. They love to swirl them around their mouths like Bordeaux wine. ~Pat Conroy Baseball? It's just a game - as simple as a ball and a bat. Yet, as complex as the American spirit it symbolizes. It's a sport, business - and sometimes even religion. ~Ernie Harwell, "The Game for All America," 1955 Why does everybody stand up and sing "Take Me Out to the Ballgame" when they're already there? ~Larry Anderson All requests for leave of absence on account of grandmother's funeral, sore throat, housecleaning, lame back, turning of the ringer, headaches, brain storm, cousin's wedding, general ailments or other legitimate excuses must be made out and handed to the boss not later than 10 a.m. on the morning of the game. ~Traditional gag notice hung in offices and factories at a time period when all games were played during daylight hours Baseball is reassuring. It makes me feel as if the world is not going to blow up. ~Sharon Olds, This Sporting Life, 1987 A game of great charm in the adoption of mathematical measurements to the timing of human movements, the exactitudes and adjustments of physical ability to hazardous chance. The speed of the legs, the dexterity of the body, the grace of the swing, the elusiveness of the slide - these are the features that make Americans everywhere forget the last syllable of a man's last name or the pigmentation of his skin. ~Branch Rickey, May 1960 Ninety feet between home plate and first base may be the closest man has ever come to perfection. ~Red Smith Baseball, it is said, is only a game. True. And the Grand Canyon is only a hole in Arizona. ~George F. Will, Men at Work: The Craft of Baseball, 1990 They are supposed to be dispassionate dispensers of Pure Justice, icy islands of emotionless calculation. In short, umpires should be acute Republicans. ~George F. Will, 1990 Baseball is a ballet without music. Drama without words. ~Ernie Harwell, "The Game for All America," 1955 Baseball statistics are like a girl in a bikini. They show a lot, but not everything. ~Toby Harrah, 1983 Spread the diaper in the position of the diamond with you at bat. Then fold second base down to home and set the baby on the pitcher's mound. Put first base and third together, bring up home plate and pin the three together. Of course, in case of rain, you gotta call the game and start all over again. ~Jimmy Piersal, on how to diaper a baby, 1968 Baseball is the only game left for people. To play basketball, you have to be 7 feet 6 inches. To play football, you have to be the same width. ~Bill Veeck, 1975 Baseball is drama with an endless run and an ever-changing cast. ~Joe Garagiola, Baseball is a Funny Game Most games are lost, not won. ~Casey Stengel England and America should scrap cricket and baseball and come up with a new game that they both can play. Like baseball, for example. ~Robert Benchley
Page Information: www.quotegarden.com/world-series.html Last modified 2010 Sep 09 Thu 20:33 PDT


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CHARLESTON, W.Va. -- More than 240 insurance companies have filed to carry workers' compensation insurance in West Virginia, but one company maintains half of the business in the state.
That would be BrickStreet Insurance, the Charleston-based company formed as a quasi-private company when the state decided to privatize its workers' comp business.
For a couple of years, BrickStreet was the only game in town, and all of the state's workers' comp business went there. Since July 2008, other companies have been allowed to participate in the workers' comp market. As of mid-August, 241 workers' comp carriers had filed with the state Insurance Commission.
But as of the end of last year, BrickStreet still handled 50 percent of the workers' comp premiums in the state, according to the Insurance Commission.
BrickStreet officials say the privatization has been a rousing success. They say employers' workers' comp costs have been cut in half, and workplace injuries are reported more quickly.
"Claimants are also receiving quicker care and better care today," said Greg Burton, BrickStreet's president and CEO.
"In 2006, only 10 percent to 15 percent of claims came in within 48 hours after the accident. Today, it is 50 percent," Burton said. "Medical costs are also going down. BrickStreet is working with health-care providers to get people back to work more quickly."
T.J. Obrokta Jr., BrickStreet's senior vice president and general counsel, said, "The old system generated a lot of litigation. Today, that litigation has dropped by 70 percent."
Protests about claims decisions have also dropped, Obrokta said, from about 25,000 protests in 2006 to only a projected 5,000 this year.
Both Burton and Obrokta worked for the old state Workers' Compensation Division, and moved to BrickStreet under privatization. The move was initiated under former Gov. Bob Wise and completed under former Gov. Joe Manchin.
Sue Howard, a Wheeling lawyer who has represented workers' comp claimants for many years, believes privatization "has become problematic for claimants dealing with Workers' Comp insurance carriers who are out of state and not well-trained in West Virginia law.
"It has been a nightmare for certain claimants who get claims mangers who don't properly administer their claims.
"There needs to be more information provided to injured workers about how to file complaints with the Insurance Commissioner when conduct is improper," Howard said.
"When BrickStreet started operating [in 2006], it was able to hire a lot of claims adjusters from the old West Virginia Workers' Compensation Commission, who had more experience and training. I see fewer problems with BrickStreet than with other private carriers. I think it is a training issue," Howard said.
BrickStreet also has its critics. Charleston lawyer James Humphreys, a former Democratic state senator and congressional candidate, opposed the privatization of workers' comp in the Legislature.
"BrickStreet has made an ungodly amount of money," Humphreys said. "Workers' compensation should not be about profits for a corporation. It should be about protecting and supporting injured workers.
Last year, BrickStreet collected $250.6 million in premiums and incurred $102.3 million in losses, according to its annual statement filed on Dec. 31, 2011. The company's net income was $47.1 million


text:
Social Networking for Fashion Doll Lovers
Time: October 28, 2010 to October 30, 2010
Location: Hyatt Regency Pittsburgh Airport Hotel
City/Town: Pittsburgh
Website or Map: http://www.integritytoys.com/…
Event Type: doll, convention
Organized By: Integrity Toys
Latest Activity: May 27, 2010
Export to Outlook or iCal (.ics)
The Integrity Toys Convention!
Integrity Toys and Jason Wu Present
Dark Romance
The convention is limited to 350 guests! Don't miss out, register today before it's too late and the convention is sold out!
© 2014 Created by Simon Farnworth.
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By Food & Wine
Easy and fast, these tacos are great for a weeknight dinner. Adding jalapeño to the chicken gives it a nice, unexpected heat. More Taco Recipes
Easiest Chicken TacosEasiest Chicken Tacos
2 cups shredded rotisserie chicken
1 small jalapeño, thinly sliced crosswise
2 tablespoons extra-virgin olive oil
Kosher salt
Freshly ground pepper
1 cup finely shredded green cabbage
1 tablespoon fresh lemon juice
1 tablespoon fresh lime juice
1/2 teaspoon hot sauce
Warm corn tortillas, shredded pepper jack cheese, guacamole and cilantro leaves, for serving
1. Preheat the oven to 350°. In a medium baking dish, toss the chicken with the jalapeño and 1 tablespoon of the olive oil and season with salt and pepper. Cover with foil and bake for about 10 minutes, until hot.
2. Meanwhile, in a medium bowl, toss the cabbage with the lemon juice, lime juice, hot sauce and the remaining 1 tablespoon of olive oil; season with salt and pepper.
3. To serve, fill warm corn tortillas with the chicken, cabbage, cheese, guacamole and cilantro.
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text:
Product description IVECO DAILY Workshop Manual
Tired of paying high repair costs to your mechanic to fix your IVECO DAILY?
If so, we have the perfect solution for you. Here is a repair manual to fix and or service your IVECO DAILY. This manual will give you a full parts list down to every nut and screw.
Models / Engines:
These manuals contain photos and diagrams as used by professional mechanics and repair shops to troubleshoot and fix your engine. These manuals have plenty of pictures and diagrams to make the entire repair process easy for you. Save money by doing your own repairs, diagrams, detailed parts lists, manuals to save or print at any time, covers every detail.
This workshop manual is in an easy to use pdf format which is suitable for all types of machines with an pdf reader.
Topics Included:
Routine maintenance of your engine has several benefits: improves engine performance, reduces fuel consumption by up to 10%, reduces emissions by up to 10%, and more.
Easy to navigate and print
Plus much more information
These manuals are used by case repair mechanics; they contain very detailed diagrams and descriptions. The manuals give comprehensive information on your parts for case and much more. At the click of a mouse you have access to the most comprehensive diagnostic, repair and maintenance information as used by professional mechanics, technicians and repair workshops.
Very clear and precise diagrams and instructions,
That are designed to get the information you need quickly and easily.
Covering all applicable models to view and print.
This item is a download please give a valid email address when ordering.
We have more manuals in our shop, please use the navigation or search from this page.
Any queries please email us for further details.
Suitable for all Windows, MAC and Linux systems
Keywords:Iveco Daily Workshop Manual Download,Iveco Daily Service Manual,Iveco Daily Repair Guide,Iveco Daily Workshop Manual,Iveco Daily Operators Manual,Iveco Daily Repair Manual,Iveco Daily Electronic Parts Catalogue,Iveco Daily Manual,Iveco Daily Wiring Diagrams


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Shine in the most popular designs and enhance your jewelry with 12 favorite projects you can have right now! Best of Stringing Crystals is an easy-to-follow, instant download eBook packed with stunning jewelry projects, handpicked from the trusted experts at Stringing magazine.
Download this must-have resource today to:
-Get instant access to stunning projects and expert how-tos. -Master 12 of the most popular pearl designs from Stringing magazine. -Create the perfect piece with helpful hints and step-by-step instructions. -Skip the guesswork with full-color illustrations and detailed tool and material lists. -Use endless variations to create even more one-of-a-kind designs!
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text: When it comes to distinguishing among brands and models of wakesurf boards, questions of material and the weight of the boards usually come down to personal preference. Most wakesurf boards include at least some fiberglass for durability and buoyancy, and smaller boards weigh less than larger boards. But don't forget these additional features that impact the speed and ride of your wakesurf board:


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Good Housekeeping is a trusted source for inspirational ideas on health, family, food, and home. Your subscription is stamped with the Good Housekeeping Research Institute's seal of approval. Every piece of advice is thoroughly tested to make sure you are getting only the information that's best for you and your family. It's time for you to put this magazine to the test.
For a limited time, get an exclusive tote bag with your subscription - your free gift! Durably constructed with bottom and easy-carry straps, it is both roomy and water-resistant. This handy tote is perfect for all your on-the-go essentials.


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Christmas Gifts for Pre-School Girls - Books & Magazines
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John & Lisa Matthews
From Openwaterpedia
John and Lisa Matthews own the escort boat JAWS that guides swimmer for the Farallon Islands Swimming Federation. They provide escort services for solo and relay swims in the waterway between the Farallon Islands and the Golden Gate Bridge.This 30-mile course is renowned to be one of the two most difficult, coldest, most perilous marathon swims in the world. Water temperatures can range from 50°F (10°C) to 55.4°F (13°C), but temperatures have been recorded lower on several occasions. The water conditions are usually extremely rough with cresting ocean swells up to 20 feet. Currents and tides often exceed the speed of the fastest swimmers. It is a swim not lightly attempted.
Contents |
Escort Boat
JAWS is a Grand Banks 32 that is available for escorting solo and relay swimmers.
Photos & Videos
Photos and videos from the The Farallons Islands Swimming Federation are located here.
Real-time GPS Tracking
Real-time GPS tracking of solo and relay swimmers are provided by the Farallon Islands Swimming Federation.
Contact information for the Farallon Islands Swimming Federation is here.


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A Safety and Effectiveness Study of SABER™-Bupivacaine for Pain Following Shoulder Surgery
This study has been completed.
Information provided by:
ClinicalTrials.gov Identifier:
First received: January 5, 2009
Last updated: February 4, 2010
Last verified: February 2010
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
This is a research study testing SABER™-Bupivacaine (an experimental pain-relieving medication). SABER™-Bupivacaine is designed to continuously deliver bupivacaine, a common local anesthetic, for a few days in order to treat local post-surgical pain.
The purpose of this study is to investigate safety (if there are any side effects) associated with the use of SABER™-Bupivacaine and how well it works in reducing pain and opioid-related side effects following shoulder surgery.
Condition | Intervention | Phase |
Postoperative Pain |
Drug: SABER™-Bupivacaine Drug: SABER™-Placebo |
Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor) Primary Purpose: Treatment |
Official Title: | A Double-Blind, Multi-Center, Placebo-Controlled Trial of SABER™-Bupivacaine for Post-Operative Pain Control and Opioid Sparing/Opioid-Related Adverse Event Reduction Following Arthroscopic Shoulder Surgery |
Resource links provided by NLM:
Further study details as provided by Durect:
Primary Outcome Measures:
- Pain Intensity [ Time Frame: 0 to 3 days post-dose ] [ Designated as safety issue: No ]
- Supplemental opioid use [ Time Frame: 0 to 3 days post-dose ] [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Frequency of opioid related side effects [ Time Frame: 0 to 14 days post-dose ] [ Designated as safety issue: No ]
- Pain Intensity [ Time Frame: 0 to 2 days post-dose ] [ Designated as safety issue: No ]
- Supplemental opioid use [ Time Frame: 0 to 2 days post-dose ] [ Designated as safety issue: No ]
- Time-to-first use of opioid supplemental pain medication [ Time Frame: 0 to 14 days post-dose ] [ Designated as safety issue: No ]
- Severity of opioid-related side effects [ Time Frame: 0 to 14 days post-dose ] [ Designated as safety issue: No ]
Enrollment: | 60 |
Study Start Date: | December 2008 |
Study Completion Date: | October 2009 |
Primary Completion Date: | October 2009 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: Group 1: SABER™-Bupivacaine
5.0 mL SABER™-Bupivacaine/Once
Drug: SABER™-Bupivacaine
Injectable Extended Release Solution; 5.0 mL SABER™-Bupivacaine/Once
Placebo Comparator: Group 2: SABER™-Placebo
5.0 mL SABER™-Placebo/Once
Drug: SABER™-Placebo
Injectable Solution; 5.0 mL SABER™-Placebo/Once
Ages Eligible for Study: | 18 Years to 65 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Patients must be able to read and understand the consent form, provide written consent, complete trial-related procedures, and communicate with the trial staff.
- Males and females, 18 to 65 years of age, scheduled for shoulder surgery.
- Patients must be healthy or have only mild systemic disease.
- Patients must have ECG wave form within normal limits
- Patients must have blood pressure within normal range.
- Male and female patients must agree to use medically acceptable method of contraception throughout the entire trial period and for 1 week after the trial is completed.
- Patients must refrain from strenuous activities and avoid changes to prescribed exercise levels throughout the course of the trial.
Exclusion Criteria:
- Patients with previous arthroscopic surgery or open surgery on the study shoulder.
- Patients with chronic pain conditions requiring continuous use of corticosteroids for greater than 3 months.
- Patients with fibromyalgia, rheumatoid arthritis, and/or sero-negative inflammatory arthropathies.
- Patients with a below normal calculated creatinine clearance.
- Patients who are pregnant or lactating.
- Patients currently receiving more than 20 mg of hydrocodone daily (or equivalent narcotic dose) on routine basis.
- Patients, who in the Investigator's opinion, have developed opioid tolerance.
- Patients with current or regular use of anticonvulsants, antiepileptics, antidepressants, or monoamine oxidase inhibitors at screening.
- Patients with current or regular use of drugs known to significantly prolong the QTc interval
- Patients with known hypersensitivity to local anesthetic agents of the amide type (e.g., lidocaine, bupivacaine).
- Patients with known hypersensitivity to opioids.
- Patients with conditions contraindicated for use of opioids.
- Patients with known or suspected abuse of opioids or other illicit drugs.
- Patients with known or suspected alcohol abuse.
- Participation in another clinical trial at the same time or within 30 days of this trial.
- Patients who, in the Investigator's opinion, should not participate in the trial or may not be capable of following the trial schedule for any reason.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00818363
Australia, New South Wales | |
Westmead, New South Wales, Australia, 2145 | |
Australia, Queensland | |
Kippa Ring, Queensland, Australia, 4021 | |
Australia, South Australia | |
Adelaide, South Australia, Australia, 5000 | |
Toorak Gardens, South Australia, Australia, 5065 | |
Australia, Victoria | |
Geelong, Victoria, Australia, 3220 | |
Hampton, Victoria, Australia, 3188 | |
Ringwood East, Victoria, Australia, 3135 | |
New Zealand | |
Christchurch, New Zealand | |
Hamilton, New Zealand |
Sponsors and Collaborators
Study Director: | Dmitri Lissin, MD | Durect Corporation |
More Information
No publications provided by Durect
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by Durect:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on March 10, 2014
No publications provided by Durect
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Janine Wong, Senior CRA, DURECT Corporation |
ClinicalTrials.gov Identifier: | NCT00818363 History of Changes |
Other Study ID Numbers: | C803-017 |
Study First Received: | January 5, 2009 |
Last Updated: | February 4, 2010 |
Health Authority: | Australia: Department of Health and Ageing Therapeutic Goods Administration New Zealand: Medsafe |
Keywords provided by Durect:
Postoperative pain shoulder surgery opioid |
Additional relevant MeSH terms:
Pain, Postoperative Postoperative Complications Pathologic Processes Pain Signs and Symptoms Bupivacaine Analgesics, Opioid Anesthetics, Local Anesthetics |
Central Nervous System Depressants Physiological Effects of Drugs Pharmacologic Actions Sensory System Agents Peripheral Nervous System Agents Central Nervous System Agents Therapeutic Uses Analgesics |
ClinicalTrials.gov processed this record on March 10, 2014


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World news about "Hungarian politics" published by euronews.
Deutsche Telekom has signed an agreement for major investment in Hungary. Hundreds of millions of euros will be spend on creating a nationwide high speed… 21/02/2014
Hungary's far-right Jobbik party has held a pre-election rally in a former synagogue, much to the dismay of protesters from the country's most prominent… 15/02/2014
It is a deal that has divided Hungary. As parliament backed controversial plans to expand the country's only nuclear power plant, opposition Green MPs made… 06/02/2014
There is alarm among homeless people in Hungary over a new law passed this week that critics say criminalises sleeping rough in some areas. From next week… 02/10/2013
MEPs have again hit out at Hungary's recent constitutional reforms, calling them undemocratic. Portugal's Rui Tavares, the Green MEP behind a report on… 02/07/2013
For the 10th month running Hungary's central bank has reduced its main interest rate by 0.25 percent. It is now at 4.5 percent, down from seven percent… 28/05/2013
The smiles may be slightly forced when Germany's Angela Merkel and Hungary's Viktor Orban meet at Wednesday's EU summit following a spat between their… 21/05/2013
"Death to the Jews!" "Auschwitz isn't this way!" "We're taking you to a free campsite, with heating!" "No return ticket!" Slogans like these were heard in… 26/04/2013
MEPs are divided over Hungary's planned constitutional reforms that the EU argues could be a threat to human rights. The row centres on a proposal to curb… 17/04/2013
The Hungarian parliament has come in for a fresh barrage of criticism after passing a raft of controversial reforms, which critics say will weaken the… 12/03/2013
In a vote that has been opposed by the EU, the US and human rights groups the Hungarian parliament on Monday adopted legislation that critics say will shackle… 11/03/2013
The decision by Hungary's Constitutional Court to reject a ban on Nazi and Communist symbols has been deemed unworkable by several political groups. Some… 20/02/2013
Alex Taylor, Euronews: "Opposition media closed down, moves to make the justice and banking systems dependent on the government. The President of the European… 21/02/2012
Hungary is continuing on a collision course with Brussels over the independence of its central bank. The European Commission wants Budapest to change a… 17/02/2012
As the last opposition radio station in Budapest loses its licence, many fear the country is slipping from a liberal, to an authoritarian state. The finger of… 27/01/2012
Thousands of Hungarians turned out onto the streets of Budapest to protest against the country's far-right Jobbik party after one of its members called for a… 03/12/2012
A far-right Hungarian MP has sparked protests after calling for Jews to be registered as threats to national security. Hundreds of people rallied in… 28/11/2012
Croatian Deputy Prime Minister Radimir Cacic has resigned after a Hungarian court sentenced him to 22 months in prison for causing a fatal car crash in 2010… 15/11/2012
Hungarian President Pal Schmitt has resigned after being involved in a plagiarism scandal. Semmelweis University in Budapest stripped him of his Ph.D in… 02/04/2012
Beleaguered Hungarian President, Pal Schmitt, has repeated his refusal to step down over a plagiarism scandal – a day after hundreds gathered in Budapest… 01/04/2012
Hungarian President Pal Schmitt has refused to resign over a plagiarism scandal. The 69-year-old was stripped of his doctorate on Thursday after he was… 30/03/2012
Hungarian President Pal Schmitt has been stripped of his doctorate, after an investigation revealed he plagarised large parts of his 1992 thesis. Critics… 30/03/2012
About a hundred new members of a Hungarian far-right group have been sworn in at a very public ceremony in Budapest. They would have broken the law if they… 18/03/2012
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Positive divergences in some technical indicators suggest rally potential that is largely unexpected, prompting selective new buying in health care stocks and profit taking in a popular inverse ETF.
Global sentiment for stocks early Monday was almost as negative as it was last October with sharply lower trading before the NYSE opening. In early trading, the S&P futures were down over ten points from Friday's close, but then managed to close the day with just minor losses.
As I noted here last week, not all of the regular sentiment readings are currently negative enough to suggest a major market low, although the financial media has been painting a dire picture.
More importantly, if the positive divergences in many of the technical indicators—especially the market internals—are confirmed, it will favor a rally that is much stronger than the bears expect.
Stock index futures are higher before the opening Wednesday, and confirmation of the positive divergences could occur before the end of the week.
We have been doing some light buying recently and have two new recommendations in the health care sector. We will also look to take some profits on an inverse ETF position.
Chart Analysis: The daily chart of the Spyder Trust (SPY) shows a pattern of lower lows, line b. The 38.2% support level at $128.92 was violated last week, as was the still-rising 200-day moving average (MA).
The double-bottom formation in the ProShares Short S&P 500 ETF (SH) was noted here in early May and was confirmed by the close above resistance at line g.


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6901 N. 72nd Street, Omaha, NE 68122
Alegent Creighton Health Immanuel Rehabilitation Center in Omaha offers comprehensive inpatient and outpatient physical rehabilitation services designed to restore function and help patients recover to their fullest extent.
Comprehensive Inpatient Program
Alegent Creighton Health Immanuel Rehabilitation Center, the region's most comprehensive center for physical medicine and physical rehabilitation offers services to help patients reduce physical and cognitive limitations caused by conditions such as brain injuries, spinal cord injuries, amputations, multiple trauma and strokes. A team of licensed and certified rehabilitation professionals is available at every level of care, from inpatient hospitalization, to acute rehabilitation, outpatient therapy and wellness programs. Each rehabilitation program is designed to maximize independence and quality of life and delivered in a warm and caring environment.Physical Rehab Facilities
Immanuel's already state-of-the-art physical rehabilitation center has added a spacious fitness facility and a specially-designed, warm-water pool with a moveable floor for inpatient and outpatient aquatic therapy. Another highlight of the renovation is a high-tech Kinesis circuit training system, which helps patients of all abilities improve their strength, balance, coordination and flexibility. And because the system is ceiling- and wall-mounted, it also can be used by patients in wheelchairs or with limited mobility. Kinesis allows therapists to get better information to make treatment more specific to the deficit each patient has.Physical Rehabilitation Care Team
Each rehab. patient is assigned a coordinator who works closely with the patient, family and care team to provide a coordinated rehabilitation experience. Other physical rehab. team members may include: a doctor of physical medicine (physiatrist), physical therapist, occupational therapist, speech therapist, recreational therapist, a physician specializing in rehabilitation medicine, rehabilitation nurses and a rehabilitation neuropsychologist and chaplains.Family Involvement
We recognize that the rehabilitation process also affects the patient's family. Family support is an integral part of the recovery process and we encourage their active involvement. We also believe it is important for family members to understand their loved one's recovery process, so we offer educational, neuropsychology, and support services to assist families.Transitioning to Other Levels of Care
After the inpatient physical rehabilitation stay, the patient may require services that are addressed at a different level of care. We assist with the transition to the next step in recovery. Follow-up treatment may range from skilled care, transitional living and home health services to outpatient care. A physiatrist monitors the patient at intervals that are appropriate to assess his health care needs. Typically 75% of inpatients are moved to a community living environment.Comprehensive Services
As part of Alegent Creighton Health, a fully integrated healthcare system, patients have access to acute inpatient care and a comprehensive array of services including: sub-acute care, outpatient programs, orthopedic services senior health services, home health, adaptive technology, driver's assessment and education, sports and leisure programs, support groups, aquatic programs and sports and leisure programs that promote health and wellness.CARF Accreditation
Immanuel Rehabilitation Center has received the highest level of accreditation awarded by the Joint Commission, an accrediting body for hospitals and healthcare organizations and by the Commission on Accreditation of Rehabilitation Facilities (CARF). A team of licensed and certified rehabilitation professionals is available at every level of care, from inpatient hospitalization, to acute rehabilitation, and outpatient therapy. Each rehabilitation program is designed to maximize independence and quality of life and delivered in a warm and caring environment.


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Explaining high-frequency trading
High-frequency trading is creating a ruckus on Wall Street. Marketplace Senior Editor Paddy Hirsch explains what high-frequency trading is and why some people are up in arms about it.
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sarah go replied on Permalink
Golden Networking (http://goldennetworking.net) is organizing the High-Frequency Trading Experts Workshop 2010 (http://www.HFTExpertsWorkshop.com), "Practical Implementation of High-Frequency Trading Strategies," on December 9th and 10th in New York City. It has been recommended for executives in finance and investments who work at Investment Banks, Hedge Funds, Pension Funds, Broker Dealers, Consultancy Groups, Prime Brokers, Solution Providers and Exchanges and wish to gain a thorough understanding and practical knowledge of high-frequency trading.
Peter Bent replied on Permalink
I dont see the point of buying all available shares in the market. The investor wants to buy at 25 dollars at max. The current price is 24.50. When the HFT sends out the 25 dollar offer and buys the rest of the shares in the market then those other shares will be either less or above 25 dollars. If they are above 25 dollars, the HFT will lose money on selling them to the investor for 25 dollars - so thats a no go. If they are less than 25 dollars, then why did the investor not buy these share himself? Because he is not quick enough?
Vasant Dhar replied on Permalink
Small error/omission in Paddy Hirsch's whiteboard on HFT. The liquidity rebate applies to limit orders only, so to say that a trader gets a rebate on *every* share traded is incorrect.
Indranil Bhatta... replied on Permalink
I look forward Paddy Hirsh's whiteboards. They are so simple yet covers teh subject so well.
However in this case, I think he started off very well explaining HFT but lost out in the middle.
* Should have explained how a $24.5 bid is met by $25 ask.
* Program trading needs more explaining
* Good example on Flash trading - Very simple for a street guy
* Can we have a session on the type of algos these 'v.intelligent' techies in the wall street creates.
Don Hall replied on Permalink
Thanks for the report.
I am so tired of people leaking money out of the economy in ways such as this. An investment is supposed to support the work of others in industry, then all share in money made out on the street. When an "investment" makes money by teasing industry with churned money, there is only benefit to the churner, and industry withers and dies.
p h replied on Permalink
I enjoyed the presentation by Mr. Hirsch but he perpetuates the myth that the people who write these algorithms are very intelligent and therefore very expensive. Having been a research director for major Wall Street firms and having been quoted in major finance journals I think I have a bit of a grasp on this crowd's general level of sophistication. Most of this stuff is not rocket science, and the vast majority of these programmers, developers and researchers are paid huge sums simply because the firms make large amounts of money on the back of increasingly opaque instruments and techniques. There are just as intelligent people elsewhere. Reports (like this one) stating that those involved in quantitative trading techniques are somehow at the top of the intelligence chain are vastly exaggerated.
Philip Roe replied on Permalink
I listened with fascination and dismay to your piece on high-frequency trading. The relationship between a market and the society in which it thrives is that between a parasite and its host, mutually beneficial provided that it remains in balance. Adam Smith's invisible hand assumes that self-interested trading is of benefit both the society and the market. But society benefits from the well-considered direction of resources, but individual traders benefit from anticipating the decisions of other traders, even by milliseconds. Trading faster benefits noone but the traders. Could you please ask somebody what the social gain is from high-frequency trading? If they say that it creates a more efficient market, could you then ask them to define efficiency very carefully? Phil Roe
Tom Benner replied on Permalink
This is just another example of how capitalism has changed for the worse. Creating something has been substituted for creating nothing. How does this help the economy grow, help Americans, help the world? It doesn't! Why does the SEC allow this practice?
B. M. replied on Permalink
OK job on the explanation, but he used a very bad example. So this video really doesn't explain how the fast-trader makes money on the $24.50 bid $25.00 ask trades. Unrealistic to think spreads are so wide that a flash order to sell at $27.00 would be met with anything other than delivery to a long stack of lazy orders in the system, same for $26.00 order to sell. Give people a realistic example, we aren't dummies.
I also don't buy that the fast-traders can't tell the orders are coming from the same buyer. There's SOME anonymity to the order postings, but there's also some id/traction on the buyer depending on the exchange. So you should also use real exchanges in your examples.
Also, you make it seem like these "algorythms" are so complicated, no one bother to explain them. They aren't that complicated, I assure you, no more than some options math which most people with a business degree (95% of Wall Streeters and a good percentage of Main Streeters) can understand.
So overall I give this video a 3 stars out of 5. A 10 year old child should be able to understand this stuff, it's really not that hard how big Wall Street firms clip money off institutional and retail orders. Institutions ought to get a GOOD 5-star explanation for all the money they are paying middlemen, THEN maybe you'd get some market solutions, instead of crying to the government-- whom will inevitably botch this thing up even worse than it already is. After all, where do you think politicians get their money? That's right, from the guys making all the easy money. So don't expect anything good to happen if gov't intervenes, it'll be more of the same, and worse.
There is only one solution, and that's to offer a market with truly opaque order flow, with only one settlement engine for matched orders. Unfortunately, the existance of such markets have been tried in the past, and the liquidity directors (big banks) direct their volumes elsewhere, to other markets that don't prevent them from making the easy money. So unless I'm missing something, nothing will ever change.
The best thing to do is for the gov't to let big banks fail when they screw up. At least it gives more honest hard-working firms some reward for doing a better job for customers. What we did in the past year is deplorable, handing the bandits bullets. I prefer new bandits, the old ones need to learn their lesson which greed bestows on them.
Mark McBride replied on Permalink
I googled "liquidity rebate" to find out more and found many results saying the NYSE started offering liquidity rebates March 1 2009. Did they get rid of it again or was that part of the whiteboard incorrect?
PS- I <3 whiteboard. Thanks!
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