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15 U.S. Code § 80b–13 - Court review of orders
Petition; jurisdiction; findings of Commission; additional evidence; finality
Any person or party aggrieved by an order issued by the Commission under this subchapter may obtain a review of such order in the United States court of appeals within any circuit wherein such person resides or has his principal office or place of business, or in the United States Court of Appeals for the District of Columbia, by filing in such court, within sixty days after the entry of such order, a written petition praying that the order of the Commission be modified or set aside in whole or in part. A copy of such petition shall be forthwith transmitted by the clerk of the court to any member of the Commission, or any officer thereof designated by the Commission for that purpose, and thereupon the Commission shall file in the court the record upon which the order complained of was entered, as provided in section
2112 of title
28. Upon the filing of such petition such court shall have jurisdiction, which upon the filing of the record shall be exclusive, to affirm, modify, or set aside such order, in whole or in part. No objection to the order of the Commission shall be considered by the court unless such objection shall have been urged before the Commission or unless there were reasonable grounds for failure so to do. The findings of the Commission as to the facts, if supported by substantial evidence, shall be conclusive. If application is made to the court for leave to adduce additional evidence, and it is shown to the satisfaction of the court that such additional evidence is material and that there were reasonable grounds for failure to adduce such evidence in the proceeding before the Commission, the court may order such additional evidence to be taken before the Commission and to be adduced upon the hearing in such manner and upon such terms and conditions as to the court may seem proper. The Commission may modify its findings as to the facts by reason of the additional evidence so taken, and it shall file with the court such modified or new findings, which, if supported by substantial evidence, shall be conclusive, and its recommendation, if any, for the modification or setting aside of the original order. The judgment and decree of the court affirming, modifying, or setting aside, in whole or in part, any such order of the Commission shall be final, subject to review by the Supreme Court of the United States upon certiorari or certification as provided in section
1254 of title
(Aug. 22, 1940, ch. 686, title II, § 213,54 Stat. 855; June 25, 1948, ch. 646, § 32(a),62 Stat. 991; May 24, 1949, ch. 139, § 127,63 Stat. 107; Pub. L. 85–791, § 26,Aug. 28, 1958, 72 Stat. 949; Pub. L. 100–181, title VII, § 706,Dec. 4, 1987, 101 Stat. 1264; Pub. L. 111–203, title IX, § 985(e)(3),July 21, 2010, 124 Stat. 1935.)
2010—Subsec. (a). Pub. L. 111–203substituted "principal office or place of business" for "principal place of business".
1987—Subsec. (a). Pub. L. 100–181substituted "section
1254 of title
28" for "sections 239 and 240 of the Judicial Code, as amended".
1958—Subsec. (a). Pub. L. 85–791, in second sentence, substituted "transmitted by the clerk of the court to any member of the Commission, or" for "served upon any member of the Commission, or upon", substituted "file in the court" for "certify and file in the court a transcript of", and inserted "as provided in section
2112 of title
28", and which, in third sentence, substituted "petition" for "transcript", and "jurisdiction, which upon the filing of the record shall be exclusive" for "exclusive jurisdiction".
Change of Name
Act June 25, 1948, eff. Sept. 1, 1948, as amended by act May 24, 1949, substituted "court of appeals" for "circuit court of appeals".
Effective Date of 2010 Amendment
Amendment by Pub. L. 111–203effective 1 day after July 21, 2010, except as otherwise provided, see section 4 ofPub. L. 111–203, set out as an Effective Date note under section
5301 of Title
12, Banks and Banking.
Transfer of Functions
For transfer of functions of Securities and Exchange Commission, with certain exceptions, to Chairman of such Commission, see Reorg. Plan No. 10 of 1950, §§ 1,
2, eff. May 24, 1950, 15 F.R. 3175, 64 Stat. 1265, set out under section
78d of this title.
The table below lists the classification updates, since Jan. 3, 2012, for this section. Updates to a broader range of sections may be found at the update page for containing chapter, title, etc.
The most recent Classification Table update that we have noticed was Tuesday, August 13, 2013
An empty table indicates that we see no relevant changes listed in the classification tables. If you suspect that our system may be missing something, please double-check with the Office of the Law Revision Counsel.
15 USC | Description of Change | Session Year | Public Law | Statutes at Large |
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June 27, 2003 Hospital, firefighters remind July 4th revelers to 'think first' about safety By Jim Albritton Health and Research News Service
JACKSON, Miss.—Fireworks vendors are predicting booming fireworks sales this Independence Day, a trend fueled by post-war patriotism and an increase in the number of states that permit the pyrotechnics. To prevent a corresponding rise in Fourth of July injuries, holiday revelers are being reminded that incorrect use of fireworks can turn a joyful celebration into a dangerous event. "Most fireworks can be relatively safe with proper and careful use," said Dr. David Collipp, medical director of the rehab surgery program at Methodist Rehabilitation Center in Jackson. "However, some fireworks are very dangerous and can result in deaths, loss of eyesight, severe burns and amputation." Children are at particular risk for fireworks-related injuries, said Lauren Fairburn, director of Think First, Methodist Rehab's statewide injury prevention program. "According to a U.S. Product Safety Commission study of fireworks injuries from June 22 to July 22, 2001, children under 15 years old accounted for about half of the number of fireworks injuries and children ages 10 to 14 had the highest injury rate," Fairburn said. "Most of those injuries were related to firecrackers, rockets and sparklers – just the kind of items that many parents buy for their kids." State law in Mississippi permits "consumer fireworks" as defined by the Department of Transportation, but prohibits cherry bombs, tubular salutes, repeating and aerial bombs and torpedoes. Jackie Moore, fire safety educator for the Jackson Fire Department, says to check with your local police department to determine which fireworks are legal in your area. "Local fireworks laws may be more stringent than the state laws, so it is best to check," said Moore. Chase Jeffreys, manager of American Fireworks off Highway 80 in Jackson, says one key to fireworks safety is to always read and follow directions. "We give each consumer firework safety tips to follow," said Jeffreys. "Sparklers, smoke bombs and poppers are suggested for young children, but only under adult supervision." Dr. Collipp and Fairburn warn parents to never allow children to light fireworks or try to re-light fireworks that have not fully ignited. They also recommend keeping a bucket of water handy in case of a fire. Here are some more tips from Methodist Rehabilitation Center for a safe celebration this Independence Day:
"The most effective way to reduce firework injuries is to focus on safety awareness and prevention," said Fairburn. "We want to do all we can to prevent traumatic, often life-changing injuries."
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subset: commoncrawl


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Suffering Benefiting from mature onset exercise addiction and low aerobic endorphin release threshold. Hoping there is no cure.
Hey Ruth,
Great news...going back is scary. Every step causes some worry. Use the Pfitz work-out and stick to it is all I can say. The schedule starts out with walk-runs which are more walking than running. It gradually builds up to running. After first few weeks you may be tempted to skip as you run more but I would recommend sticking it out till end of schedule. I also learned after Pfitz all the training errors I was doing.
Now I try to keep to a schedule with rest days [for cross training] and varying types of runs -even when not training for a race. I also observe the 10% weekly mileage rule as well with fall back weeks in mileage. In addition, I always try to stretch afterwards since muscles in leg can affect how the foot lands and pushes off and vice versa. I also retired the shoes/type that I was wearing when SF happenned.
Good luck!
Nulla camisia et nulla problematum
Bob Potts Marathon - 5/25/14
Wineglass Marathon 10/5/14
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Aura Cacia Electric Aromatherapy Air Freshener Refill Uplifting Bergamot and Orange -- 0.52 fl oz
smells really good
smells good, but the oil does not last long if you have it plugged in all the time
May 31, 2013
Nice scent!
This provides a nice smell without being overpowering. And I love that it is all natural without chemical fragrances.
April 2, 2013
Smells great
Love this product I just wish it was bigger.
October 15, 2012
fresh clean smell
I love these ! Not overpowering .
August 3, 2012
Lovely natural room fragrance!
A great alternative to traditional room fragrances, this uses pure essential oils, so great for those like myself with asthma and sensitivities to fragrance. Also love that it's a plug in, so no worries about fire risk as with candles, or spill risk with reed diffusers.
June 13, 2012


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Message board »Message Board home »Sign-in or register to get started
Online now: 2 members: Bruster55, SlopitchRR; 19 anonymousDetails for Player
Real name:
Messages posted by Player »Message board home »Start a new discussion
Jan. 30, 2014 Player | Topic: Bats Discussion: Bat Info needed Gary, I still have - and use on cold days - the gold Worth ESTs. One is a 26 oz 10 inch barrel and the other is a 30 oz 13 inch barrel. They still hit well with the new balls. Next time you visit Woodlawn, I'll let you try them. |
Nov. 17, 2013 Player | Topic: Product review Discussion: Miken Senior Bat Review- shich is the best bat of the 3? Gary, this weekend, while playing with the fifties, I traded the 28 oz white two-piece for a 30 oz white two-piece. It's broken in and popped the ball pretty well on the two at-bats I had occasion to use it. |
July 16, 2013 Player | Topic: Associations Discussion: FHC Audie is correct for the FHC. But, in addition, there are several leagues - day and evening - in the Tampa/St. Pete area. The teams are of all levels. Some are nationally ranked, some not so much. Usually, you can just show up at a venue and you'll be invited to play, as they always need player. |
July 12, 2013 Player | Topic: Tournaments Discussion: ISA COLUMBUS INDIANA But Gary, how can you go without your great Ultra II, end-loaded, two-piece? OBTW, it still hits with authority! LOL |
July 10, 2013 Player | Topic: General and miscellaneous Discussion: Lower Back Pain Home Remedies HJ is correct about the piriformis problem often being misdiagnosed. It's one of the six lateral rotators that is often forgotten when we stretch. We do our "hammies" and some others, but need to do these also. Some of us have the sciatic nerve grow inside of the piriformis, some have it grow outside of it, and others have it grow through the piriformis. This is one of the reasons it's misdiagnosed. Unfortunately, low back pain is often attributed to a skeletal problem when it is muscular. Hence, the rationale for stretching. Several such stretches for the piriformis can be found on the internet. Pick one and see if it helps, but don't start aggressively with any of them. |
May 21, 2013 Player | Topic: Bats Discussion: Solar Bat Warmes Most of the players that use these have made them. Make a small box (an old trunk lid works), use household aluminum foil on the inside, then cover with a clear plastic sheet (the big-box stores carry this). You can add props, feet, or set them against the fence. Like armiho211 suggested, cold balls (or wet ones) might be a problem though. |
March 6, 2013 Player | Topic: Tournaments Discussion: TOC 1billyd: Nothing new here. Last year in a SSUSA tourney, there was only one 70's major + team and one 65 major team in attendance. They had to play "even-up" with only the winner going to the TOC (the 65 major team). IMHO, both teams should have been invited. |
March 3, 2013 Player | Topic: General and miscellaneous Discussion: Need Cleats In Bullhead City Ed, there's gotta' be a Walmart! Or - swap a bat. LOL |
Feb. 23, 2013 Player | Topic: General and miscellaneous Discussion: Does anybody have the address....... Hey Bruce, you should visit us more often at Woodlawn. For bkb555, Dave's most recent address is email@example.com. When we see you, we'll give you all the updates. LOL |
Jan. 24, 2013 Player | Topic: General and miscellaneous Discussion: Best Pitcher Webbie, I have to agree with you about Bobby Davis. The only time he throws a "straight" ball is the occasional BP he pitches. Then he's like a machine! Game day though, I think he just "messes" with us 'cause he can! LOL |
Jan. 18, 2013 Player | Topic: Players looking to join a team Discussion: Tournment Pitcher from NY looking to join a team I would have to agree with Southernson about Bobby Davis' pitching. But, more importantly, I doubt that Cerce could even approach Bobby's power! |
Oct. 3, 2012 Player | Topic: General and miscellaneous Discussion: Woodlawn Hitting Club Warren, we hit EVERY Tuesday and Thursday at 7:30 a.m.. 'Course, if we do get rained out, there is always the fine breakfast at the old El Tenampa where we tell each other how great we were. LOL. Rainouts are few and far between, though. There's always a dry spot somewhere. Come and be welcomed! |
Sept. 3, 2012 Player | Topic: General and miscellaneous Discussion: dalton ga titanhd; Pug asked about the AAA 50's, which closes one week before on August 24th. The 55's, etc., closes on the 31st. I hope that's correct - or I'll be seriuosly late! |
Sept. 2, 2012 Player | Topic: General and miscellaneous Discussion: dalton ga Not so. According to SPA's brochure, the deadline was August 24th. Purportedly, the schedule is due tomorrow. |
Aug. 19, 2012 Player | Topic: General and miscellaneous Discussion: SOUTHERN Bruce, each team was told only the winner went to the TOC. My query; at the TOC, should the younger team play in the 70 MP brackets or should the older team play in the 65 M brackets? |
Aug. 18, 2012 Player | Topic: General and miscellaneous Discussion: SOUTHERN Bruce, suppose - just suppose - a 70 Major Plus team was required to play a 65 Major team, the best 2 out of 3, even-up, should both teams be invited to the TOC? |
June 24, 2012 Player | Topic: Bats Discussion: Miken Ultra II balanced and end load. Just my two cents; I've broken four Rebok endloads (one 28oz and three 26oz) since last November. They all performed as expected but didn't last. Being poverty stricken, I returned to the balanced (black) U2 (bpf 1.21) and am sorely disappointed - and I have well over 200 swings on it. It feels like a piece of wood when contact is made and very little distance. It's been that way from the date of purchase about two months ago. Ed, I agree, the Rebok is good. But, I can't afford the cost. |
May 31, 2012 Player | Topic: Players looking to join a team Discussion: Florida Gulf Coast Several exist. For tournament teams, try Florida Half Century at fhcsoftball.org. For leagues, check the local area (e.g. The Villages, Three Score around the Clearwater area, etc.) |
Nov. 2, 2011 Player | Topic: Teams looking for players Discussion: Anybody looking for a player for the Winter National's in Ft. Myers? What was/is the cutoff to add players to a roster for Ft. Myers? |
Oct. 23, 2011 Player | Topic: Players looking to join a team Discussion: Looking To Join a Team Are you based in OH or KY? |


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Gro-egg not included
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Mikey the monkey is one of three collectable characters that are fun companions to the Gro-egg. The Gro-egg Shells maintain all of the Gro-egg's current features including its important night light and temperature reading functions. Makes the Gro-egg more decorative and visually appealing for both children and adults, whilst maintaining its practical safety features that so many parents have come to rely upon to ensure their children have a safe night's sleep.
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Longtime Duluthian Tracy Lundeen began his career as a teenager when he joined the group Guided Tour as its lead singer. Hear that group on the compilation series "Duluth Rocked," which Lundeen put out with Jeff Jarvinen. Laurie Mattson/For the Budgeteer
Read the article: Up close and personal with 'Mr. Duluth'


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Fabulous pick! Share your favorites and earn zulily credit. see detailsconnect
Made from lightweight, petal-soft material, these breezy pants are oh-so-comfy and pull on easily thanks to an elastic waistband and cuffs. The designer sensibility in this piece is evident by the fusion of indigenous Eastern Indian dyeing techniques with a modern silhouette.


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22 hrs ago | BleacherReport
What We Still Don't Know About the NY Knicks
The New York Knicks have gone from a 54-win playoff team to a sub-.500 team on the outside looking in within the span of just one year, so there are undoubtedly plenty of questions about their makeup as a team.
Trending on the Topix Network
22 hrs ago | CBS Sports
Ex-GM Steve Kerr says he has coaching interest
Steve Kerr has been an NBA champion. He's been an NBA general manager. And he's been an NBA broadcaster.
Yesterday | CBS Local
Lichtenstein: Here's The Truth - Few Can Match Toughness Of Paul Pierce
That's the trait general manager Billy King was searching for after the Nets' inaugural season in Brooklyn ended with a Game 7 loss at home to Chicago in the first round of the 2013 NBA playoffs.
Report: Jackson Expected To Decide Monday If He'll Take Position With Knicks
The 68-year-old has won 11 titles as a coach and two as a player with none other than the Knicks.
Nets staking their claim to city
Brooklyn Nets' Marcus Thornton, right, and teammate Paul Pierce celebrate Thornton's 3-point basket against the Milwaukee Bucks The NBA is not an exact science, which is why we can't be sure the Nets are a team on the rise or simply teasing us with their impressive play of late.
Nets Wrestle Raptors for Control of the Atlantic
The Nets' Monday-night matchup with the Toronto Raptors would have been hard to pick out as a critical game before the season began.
Commissioner Silver visits Collins
The Grizzlies are 17-6 since Marc Gasol returned from injury, and for the second straight home game the Nets will face a massive size disadvantage in the front court, where Paul Pierce will likely guard either Gasol or Zach Randolph .
Carmelo Anthony Needs Playmaker For NBA Title Hopes
Since his arrival to the Big Apple, the offense primarily revolves around New York Knicks forward Carmelo Anthony .
Boomer & Carton: Jerry's Update And Craig's Never-Ending Search
With a 96-80 win over the Bulls last night in Brooklyn, the Nets improved to 29-29, which prompted Paul Pierce to do some name-calling and Jason Kidd to talk about the importance of getting to .500.
Nets smother Bulls' offense in win
The Nets beat up on one of the Eastern Conference's best Monday night at the Barclays Center.
Blame this Knicks season disaster on 2012 moves
The Knicks added Jason Kidd, Raymond Felton and Marcus Camby on multi-year deals during the summer of 2012.
Jason Collins Reportedly Will Sign 2nd 10-Day Contract with Brooklyn Nets
After his initial 10-day contract expires Tuesday, the Brooklyn Nets reportedly will sign veteran center Jason Collins to another deal that will keep him with the team for an additional 10 days.
We are excited to be joined by Josh Khalou , a Sport Management student at Ithaca College from Long Island, New York.
James Dolan: The Anti-George Steinbrenner
Jan 28, 2014; New York, NY, USA; President and CEO of Cablevision Systems Corporation and Executive Chairman of The Madison Square Garden Company James Dolan makes a phone call during the second half of the game between the New York Knicks and the Boston Celtics at Madison Square Garden.
Isola: Chicago could be Carmelo's kinda town
A young fan seated behind the Knicks bench held up a sign encouraging Carmelo Anthony to consider the Bulls - again - when he weighs his free-agent options this summer.
Nets finish road trip in Milwaukee, hope for 4-2 record
The Nets aren't as bad as their loss to Portland would indicate. Nor are they as good as their easy win over Denver.
Gay NBA player meets with Matthew Shepard's parents
"I got them a bucket," the Brooklyn Nets' center said with a chuckle. "And of course, I had what, like three, four, five fouls.
Necessity of cap space in the summer of 2015
Fans have been looking forward to 2016 for the pursuit of Kevin Durant. To me, having cap space in 2015 is just as important important in order to even be in the conversation for Durant in 2016.
The key questions & answers in Felton's case
New York Knicks point guard Raymond Felton who was arrested early Tuesday on felony weapons charges leaves Manhattan Criminal Court after his arrangement Raymond Felton faced an uncertain Knicks future entering last week's trade deadline and now faces one again post-deadline in the wake of his gun-charge arrest.
Editorial: Jason Collins, Pioneer
Today, it is Jason Collins, a member of the Brooklyn Nets and now the first openly gay player to compete in one of country's four most popular sports leagues.


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£630 pcm
2 bedroom apartment to rent Usher House, Llys Y Craig, Bryn Y Baal
Town & Country are pleased to offer for rent this Modern Two Bedroom Apartment which enjoys wonderful views to the rear and briefly comprises: Entrance Hall, Living Room, Kitchen with integrated appliances. Master Bedroom with en suite shower room and fitted furniture, bedroom two also with (cont.) More details ›
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does not include shipping and tax
List Price $17.95 Save $3.50 (19%)
Estimated in-stock date 03-15-2014
Place your order now for delivery priority!
Showing 2-star reviewsShow Other ReviewsCreate an online reviewand share your thoughts with other customers
Things I liked:They seem to be uniform and fly straight. Things I liked:They are ACCURATE in my BSA R-10! One of the great long range hunting pellets. Things I would have changed:Price! What others should know:Very accurate in BSA PCPs and airguns with Lothar Walther barrels. Great KalibrCricket ammo as well. Things I liked:I like the accuracy and the weight of the pellets firing from my Gamo Bone Collector air rifle. I actually stumbled across these from the JSB pellet sampler. These shot by far the most accurate and grouped the tightest of them all on a 15 yard target. Things I would have changed:A little pricey at $14.45 a tin. What others should know:These pellets fly straight out to 25 yards tested. Thus far, they have become my favorite .177 pellet and have knocked pest birds off tree branches and put them right to sleep. Show Other ReviewsCreate an online review and share your thoughts with other customers
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Compatible with JSB Diabolo Exact Heavy .177 Cal, 10.34 Grains, Domed, 500ct |


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Article Information
Related Articles
- Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutat...
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
Cell, Volume 148, Issue 1, 20 January 2012, Pages 59-71
Tobias Rausch, David T.W. Jones, Marc Zapatka, Adrian M. Stütz, Thomas Zichner, Joachim Weischenfeldt, Natalie Jäger, Marc Remke, David Shih, Paul A. Northcott, Elke Pfaff, Jelena Tica, Qi Wang, Luca Massimi, Hendrik Witt, Sebastian Bender, Sabrina Pleier, Huriye Cin, Cynthia Hawkins, Christian Beck, Andreas von Deimling, Volkmar Hans, Benedikt Brors, Roland Eils, Wolfram Scheurlen, Jonathon Blake, Vladimir Benes, Andreas E. Kulozik, Olaf Witt, Dianna Martin, Cindy Zhang, Rinnat Porat, Diana M. Merino, Jonathan Wasserman, Nada Jabado, Adam Fontebasso, Lars Bullinger, Frank G. Rücker, Konstanze Döhner, Hartmut Döhner, Jan Koster, Jan J. Molenaar, Rogier Versteeg, Marcel Kool, Uri Tabori, David Malkin, Andrey Korshunov, Michael D. Taylor, Peter Lichter, Stefan M. Pfister and Jan O. Korbel
SummaryGenomic rearrangements are thought to occur progressively during tumor development. Recent findings, however, suggest an alternative mechanism, involving massive chromosome rearrangements in a one-step catastrophic event termed chromothripsis. We report the whole-genome sequencing-based analysis of a Sonic-Hedgehog medulloblastoma (SHH-MB) brain tumor from a patient with a germline TP53 mutation (Li-Fraumeni syndrome), uncovering massive, complex chromosome rearrangements. Integrating TP53 status with microarray and deep sequencing-based DNA rearrangement data in additional patients reveals a striking association between TP53 mutation and chromothripsis in SHH-MBs. Analysis of additional tumor entities substantiates a link between TP53 mutation and chromothripsis, and indicates a context-specific role for p53 in catastrophic DNA rearrangements. Among these, we observed a strong association between somatic TP53 mutations and chromothripsis in acute myeloid leukemia. These findings connect p53 status and chromothripsis in specific tumor types, providing a genetic basis for understanding particularly aggressive subtypes of cancer.
Summary | Full Text | PDF (1808 kb) - Criteria for Inference of Chromothripsis in Cancer Genomes
Criteria for Inference of Chromothripsis in Cancer Genomes
Cell, Volume 152, Issue 6, 14 March 2013, Pages 1226-1236
Jan O. Korbel and Peter J. Campbell
SummaryChromothripsis scars the genome when localized chromosome shattering and repair occurs in a one-off catastrophe. Outcomes of this process are detectable as massive DNA rearrangements affecting one or a few chromosomes. Although recent findings suggest a crucial role of chromothripsis in cancer development, the reproducible inference of this process remains challenging, requiring that cataclysmic one-off rearrangements be distinguished from localized lesions that occur progressively. We describe conceptual criteria for the inference of chromothripsis, based on ruling out the alternative hypothesis that stepwise rearrangements occurred. Robust means of inference may facilitate in-depth studies on the impact of, and the mechanisms underlying, chromothripsis.
Summary | Full Text | PDF (1821 kb) - Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
Cell, Volume 144, Issue 1, 7 January 2011, Pages 27-40
Philip J. Stephens, Chris D. Greenman, Beiyuan Fu, Fengtang Yang, Graham R. Bignell, Laura J. Mudie, Erin D. Pleasance, King Wai Lau, David Beare, Lucy A. Stebbings, Stuart McLaren, Meng-Lay Lin, David J. McBride, Ignacio Varela, Serena Nik-Zainal, Catherine Leroy, Mingming Jia, Andrew Menzies, Adam P. Butler, Jon W. Teague, Michael A. Quail, John Burton, Harold Swerdlow, Nigel P. Carter, Laura A. Morsberger, Christine Iacobuzio-Donahue, George A. Follows, Anthony R. Green, Adrienne M. Flanagan, Michael R. Stratton, P. Andrew Futreal and Peter J. Campbell
SummaryCancer is driven by somatically acquired point mutations and chromosomal rearrangements, conventionally thought to accumulate gradually over time. Using next-generation sequencing, we characterize a phenomenon, which we term chromothripsis, whereby tens to hundreds of genomic rearrangements occur in a one-off cellular crisis. Rearrangements involving one or a few chromosomes crisscross back and forth across involved regions, generating frequent oscillations between two copy number states. These genomic hallmarks are highly improbable if rearrangements accumulate over time and instead imply that nearly all occur during a single cellular catastrophe. The stamp of chromothripsis can be seen in at least 2%–3% of all cancers, across many subtypes, and is present in ∼25% of bone cancers. We find that one, or indeed more than one, cancer-causing lesion can emerge out of the genomic crisis. This phenomenon has important implications for the origins of genomic remodeling and temporal emergence of cancer.
Summary | Full Text | PDF (2965 kb) - …more
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Copyright © 2013 All rights reserved.
Cell, Volume 152, Issue 6, 1199, 14 March 2013
Leading Edge
Add/View Comments (0)In This Issue
- Residing in the physical heart of the cell, the nucleus has now fully shed its once one-dimensional reputation as the repository for genetic information and steady supplier of messages to the cytoplasm. This sea change toward a more dynamic view of nuclear biology has been led by a revolution in our understanding of genomes, regulatory elements, epigenetic modifiers, and nuclear spatial organization, which has enabled the examination of the interplay of these factors both genome wide and at individual loci. From this vast and rapidly expanding body of work, we can now see that, in the cellular orchestra, the nucleus is not simply the sheet music from which the notes are played but is instead the conductor and composer, both writing the songs and leading the performance. This special issue, The Dynamic Nucleus, explores the meaning behind the maestro's motions—both dramatic and nuanced—in directing the cell symphony.


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. ;, STA'ljl~ AGRlhULTURAL l!'1IR. " . ,~'.V. e ' a.r~?, leased to Inotice that. 11. feelling of HC: . ti;Yflmterest has been a~u.k{'ned on ~he pal·t of : mallY of tlte citizJm~ of this Sta.te O~l the !lub-ject of 4gricultuta.l improvement; '~nd .it has been :a lliattcr of SUi'!)l'lseto us, th~t thIS, the ' <most important illtQre~t of the St~~e, "ihouJd, ha vo heen h i fh~rto so DJ uch neglectedf 'Ve are, ·th~l'efore. "va repent, ·gl·tt.;tified to w!itlless the in~'ea!'ICd solicitude manifested on tlJ~s accouot, and a. 'delerminll.tioll evinceu to a(hance the . etandard of A.gricultul·~ in the Old North State By way .. !)f giving aJ practical t)h~e : to this nOlY spirit, .a In. orement has :iately ~eeiJ sc.'t on. foot whieh promises the happieiOt ~e8ults, . ~ State Agricultura.l So.ciety has be¢n formed, emoracing' many ot the leading f~l'mers and others of the State, for .the purpuse /; Of:;Y.8tel1W.tizill7 'the work of improv-ement, and of infusing a.~ncw energy ~~mong those engttged in Agrio'lfltura. l pUlisu,its. For:this finlt step i~ the great work uf advancement and progres8~the public are largely indebted to (he , . ~.l.ctive a (.1. untiring es:el'tions ofDl'. Jno. F. Tumpkins, t 1e able editor of the Farmer'l'l Jou,rmd, who as uavotcu h,imsclf, ~o the c~use .with the 8pir~t9f an enthuSiast. Ihe SOCiety 1& no\y orgaUlzQdand \\1eU under wa.y, Its first Fair will be . ~eld in Ita}, ciJ!;h next week; aod [I'om the e~.ensive and li~Jera.1 arrangements made by the! citizens ,of that place, and the indications of in~te.. rest manifested by tbe fa.rmers of ma.ny por iOllS of the Sta.te, we have no doubt the exhibition will prove in every way a creditabl~ and gratifying' affair. We regret, however, that ~(, little. int~ r~!:It 8e~~ls to be ~e1t ~Y th~ ~armersof this.viCInIty. ' .1 hough rlcp lD AJ.?:rIcult~ral productiolls, we hear of no c/mtributio~8from this neighborhood. Stilt, we hope for ~. better uuy, and that the Agricultural Societr of North Carolina ma.y suceeed in giving, an ' impul$6 ,to this .great hranch of int\ustl'y w(lic~ will l;>e sen."lbly felt throughout tlhe boundaries of the } Stu.te.-Demucratic Pioneer. )
Object Description
Rating | |
Title | We are pleased to notice that a feeling of active interest has been awakened |
Date | 1853-10-19 |
Description | A short article describing the renewed interest in agricultural improvements brought about by the first North Carolina State Fair. |
Subjects |
North Carolina State Fair Agricultural exhibitions--North Carolina North Carolina--Fairs |
Time Period | (1820-1860) Antebellum |
Source | Raleigh Register, October 19, 1853 |
Local Call Number | RaRRw |
Collection | General Collection. State Library of North Carolina |
Rights | Public Domain see http://digital.ncdcr.gov/u?/p249901coll22,63753 |
Digital Characteristics | 0.55 MB |
Type | Text |
Format |
Clippings (information artifacts) Articles |
Digital Collection | Blue Ribbon Memories: Your History of the North Carolina State Fair |
Title | Page 1 |
Full Text |
. ;, STA'ljl~ AGRlhULTURAL l!'1IR. "
. ,~'.V. e ' a.r~?, leased to Inotice that. 11. feelling of HC:
. ti;Yflmterest has been a~u.k{'ned on ~he pal·t of
: mallY of tlte citizJm~ of this Sta.te O~l the !lub-ject
of 4gricultuta.l improvement; '~nd .it has
been :a lliattcr of SUi'!)l'lseto us, th~t thIS, the '


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Drew Carey, Candace Cameron Bure, and Olympic gold medalists Charlie Whiteand Meryl Davis are among the celebrities who are heading to the ballroom for Season 18 of Dancing with the Stars.
For 16 seasons, Tom Bergeron has been the maestro of the circus that is Dancing with the Stars. And even he says that the changes the show has made for its 17th season — including returning to a single-night format and changing the layout of the ballroom — have taken some getting used to.
"It's a little weird," Bergeron tells TVGuide.com of the show's new structure.
Len Goodman wants Aly Raisman to stick her butt in on Dancing with the Stars — but that won't happen this week. "It's Latin Night and we have the salsa, so you have to move your butt," she tells TVGuide.com. "Sorry, Len!" But butt-shaking isn't the only thing the Olympic champ is focused on this week. Find out what else she and Mark Ballas have planned.read more
"All-Stars" contestant reveals who he thinks his biggest rival is this season.
Kristi, Cristian and Jason prepare for a new element to the 'Dancing' finale.
Dancing with the Stars sneak peek.
"All-Stars" contestant opens up about what she does and doesn?t want this season.
More Clips & Interviews
More Credits (1)
Last Monday's Dancing with the Stars was a tough one for Aly Raisman, not just because she flubbed a move in her samba, but because the Needham, Mass., native performed hours after the Boston Marathon bombings. (Her family and friends are OK.) "It was really difficult," she tells TVGuide.com. "I just want to say that I love everyone back home from Boston. You're all in our thoughts and prayers. Mark [Ballas] and I tweeted a picture of us making a heart. We're all thinking about you. I'm so sorry that this happened. My heart goes out to everyone who's affected. Hopefully I can do well for... read more
When it comes to Andy Dick interviews, they're anything but straightforward.Dancing with the Stars boss on recapturing the magic (and viewers): "It's back to basics"We here at TVGuide.com were witness to it firsthand when he and his Dancing with the Stars partner Sharna Burgess stopped by our studio. And while Team Dick did give us details on the comedian's rehearsal meltdown (watch here), most ... read more
Last fall, a longtime goal of Dancing with the Stars producers came into fruition: an all-stars season.Thirteen alums returned, but viewers fled. The onetime ratings juggernaut delivered less-than-glittery numbers — partially due to The Voice's first fall outing siphoning eyeballs. But executive producer Conrad Green also believes it's because fans want to see dancing with new stars, not all-stars.PHOTOS: Check out the new Dancing with the Stars cast"Perhaps that was a miscalculation on our part. Maybe we underestimated how important it was to have a new story rather than a continuation of one," Green tells TVGuide.com. "We thought seeing old favorites come back would be really appealing, and I think it was to core fans of the show. All-Stars did deliver in terms of being able to try some new dances out, new challenges and really pushing the level of competition. I think what it lacked was the shock of the new. Read Derek's Dancing blog "So it's quite nice this season to go back to fresh faces, people completely unfamiliar with dance and get back to that kind of innocence," Green continues. "It's back to basics almost. There's definitely a ... read more
There will be three new pros on Dancing with the Stars when Season 16 premieres on Monday (8/7c, ABC). But while Lindsay Arnold, Sharna Burgess and Gleb Savchenko are rookies on the show, they aren't exactly new to the global Dancing family. Here's what you need to know about the fresh faces and what you can expect from them. read more


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quote:Originally posted by urban_legend racist commercial? LOL It's like you tailored that post just for me to show Blackness tomorrow! Result.
___________________ TECHNO IS THE BEST NOISE ON EARTH. Save Techno - Stop Minimal / Tech-House
___________________ Everything happens for a reason
quote:Originally posted by MissK Holy Christ Jesus! The man's my personal hero! WOW! So impressive!!
quote:Originally posted by MissK This motherfucer is clearly half-man & half-amazing. Without question the most coordinated person alive right now. I'm still shaking my head in disbelief.
___________________ "The function of music is to release us from the tyranny of conscious thought." � Sir Thomas Beecham
27CDB6E-AE6D-11cf-96B8-444553540000" alt="Old Lady Dances Crazy at Rave Funny Videos">Old Lady Dances Crazy at Rave - Watch more Funny Videos
___________________ http://www.wtf.com/
is there anyone else here who has never posted anything on youtube?
quote:Originally posted by MissK i love how they usewd the music from ninja gaiden sigma for this video. ps this guy is SICK
quote:Originally posted by ChemEnhanced is there anyone else here who has never posted anything on youtube? ME!!!!
___________________ Marco V is the MAN!!!!!
___________________ http://www.soundcloud.com/gera
quote:Originally posted by geroin To bad she's blind. Oh noes. Seriously though, saw it on the Mashable rss feed today. So here's something a little more fun that I can't wait to do when drunk in NYC. FAO Schwarz - Big PianoUploaded by soanepowate. -
Sick Robot Dance
___________________ Short time TA, Long time Guver, Good time giver.
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Elvis Toddler Jumpsuit
Item# 07209604
Make your little one the king of the neighborhood when you dress them in this officially licensed Elvis Toddler Jumpsuit. Everyone will be "All Shook Up" when they catch of glimpse of your child in this stunning jumpsuit!
- Officially licensed Elvis Toddler Jumpsuit includes:
- Jumpsuit
- Microphone and shoes not included
- Materials:
- 100 % Polyester
- Wash/Care Instructions:
- Hand Wash
All Reviews
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Displaying Reviews 1-2 of 2Back to Top
not for a tall 2 yr old
By Jane from Wilmington, NC on 11/6/2013
Bottom Line:
No, I would not recommend this to a friend
My 2 yr old is tall for his age and currently wears a 3T. The legs of the jumpsuit are way too short. Ordered a week before Halloween and very disappointed to learn that Spirit Halloween won't allow returns after October 25th.
Was this review helpful to you? Yes / No- Is this review inappropriate?.
Adorable Elvis!
By Busy Momma from Oklahoma on 10/13/2013
Comfortable, Cute, Fits Well, Lots of Fun, Unique
Material Too Warm
Best Uses:
Costume Party, Just For Fun, Trick Or Treating
Describe Yourself:
Classic, Conservative
Was this a gift?:
Bottom Line:
Yes, I would recommend this to a friend
This is an excellent costume! It fits my son perfectly. It was a bit scratchy at first, but since washing it with fabric softener, it is very comfortable. The material is different than I imagined it would be. I assumed it would be the normal light-weight, cheap-costume fabric, but it is felt. It may end up being a little too warm for Oklahoma Halloweens. It is so cute on, though! We may just have to run the air conditioner! Overall, I'm very pleased with my purchase!
Was this review helpful to you? Yes / No- Is this review inappropriate?.
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Just curious if anyone else gets the weekly fishing report via email that the Dept of Conservation sends out. I've been getting it for a few years and recently I've taken a few trips to locations I don't usually fish because the report listed them as "all species good".
I've been paying close attention to the reports this year and I've found their accuarcy to leave alot to be desired. For example if the report says bass are good on spinners and topwater, I haven't caught a single fish on those baits, but caught several on other types of baits.
I's love to hear from anyone else that gets these reports. Do you think they are accurate, or is it just me?


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Can anyone recommend a photo sharing website so that I can upload photos on here?
I used to use Photobucket a while ago, but something has happened to my account, and all my pics have been downsized to blurry little images
Any ideas?
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12:30 p.m. - 2:00 p.m. |
The New School's social justice initiative, "campus climate" refers to the ways in which various constituencies experience a college or university atmosphere. The assessment will look at the extent to which aspects of the university are equitable and just based on socioeconomic status, race, gender, sexual orientation, and other identity dimensions. Findings and insights from this project will be used to inform policy and practices intended to make The New School more equitable and just community. This event is open to members of the university community only. |
Location: Wollman Hall, Eugene Lang Building, 65 West 11th Street, 5th floor (enter at 66 West 12th Street) Admission:
Email: |


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Weekend Guide: BrunchRUN, Atlanta Moon Ride, Dunwoody Art Festival and More!
Posted on May 8th, 2013
Hello, local readers! Hot off the press is this week's edition of our weekend guide, filled with the best things to do in and around Atlanta this Thursday through Sunday. As always, be sure to add anything we missed in the comments section. Enjoy your weekend!!


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Tips to Ease the Dinner Rush Simple Ways to Ease the Dinner Rush Now by Sarah Lipoff 8/26/12 0 Reactions 7 Shares Print 2 1 4 0 0 Weeknight dinners get even crazier when everyone's timetable is different. With after-school activities, busy work schedules, and little ones running amok, getting a quick, easy, and healthy dinner on the table can be a challenge. Ease the dinner rush with a few simple tricks that guarantee results — many of which you can start tonight! Click through for some ideas the whole family can get behind. Source: Flickr user slightly everything Start Out of Sight What's Your Reaction? 0 0 0 0 0 0 Create a space where everyone's stuff gets stashed when returning home at the end of the day. This way the clutter isn't a distraction while everyone is enjoying family dinner. Take the time to make the area welcoming and organized, which will encourage everyone to do the same. Source: Flickr user Unskinny Boppy 1 / 7 Double It What's Your Reaction? 0 0 0 0 0 0 The next time you're making your family's favorite dish, cook a double (or triple) batch. Pop the extra in the freezer, making sure to write the date and dish on the ziplock bag, and you're guaranteed a quick dinner another night. Just about anything can be tossed in the freezer and still be tasty and fresh. Check out how this busy mama makes dinner a snap by cooking big batches of brown rice and freezing it in easy-to-reheat portions. Source: Flickr user aMichiganMom 2 / 7 Stock Up on Fresh Fruits and Vegetables What's Your Reaction? 0 0 0 0 0 0 Fill your pantry with fruits and vegetables, which cook quickly. This way your sides are always fresh and can easily be steamed on the stove top or microwaved in minutes. Go with seasonal fruits and veggies, which also keeps costs down. You can even start the week by slicing and dicing veggies and then keeping them crisp in ziplock bags for later in the week. Thinly slice celery, carrots, and zucchini for stir-fry or chop carrots, potatoes, and leeks for a hearty stew. Wash and dry lettuces, wrap several leaves in paper towel, and then store them in large plastic bags for quick salads. Source: Flickr user georgeparrilla 3 / 7 Canned Beans to the Rescue What's Your Reaction? 0 0 0 0 0 0 Canned beans are full of protein and are a wonderful addition to soups or stews or as a side. Only requiring minutes to make, swapping beans for frozen french fries is also a tasty way to eat healthy. On your next burger night, consider making this easy Cat Cora recipe for baked beans. 4 / 7 Take It Easy What's Your Reaction? 0 0 0 0 0 0 Opt for easy dishes instead of multistep and multipan recipes. This way you're guaranteed easy cooking — and easy cleanup. Select 30-minute recipes for weeknight dinners and plan adventurous meals for the weekends when there's more time for cooking in the kitchen. Invite kids to offer suggestions for fun dinner options, which also gives Mom a break from meal planning. Source: Flickr user sun dazed 6 / 7 Get Some Help What's Your Reaction? 0 0 0 0 0 0 Enlist anyone not cooking to make sure the table is set. Even little ones can help put out plates and napkins or be in charge of clearing plates and loading the dishwasher or sink. Giving each family member a task makes dinnertime run smoothly and creates family meal success. Source: Flickr user jules:stonesoup 6 / 7 Run the Dishwasher What's Your Reaction? 0 0 0 0 0 0 End the day to the hum of a running dishwasher, which gives you a head start on the busy day tomorrow. If you don't have a dishwasher, create a family assembly line and make washing dishes the final part of your dinnertime routine. If you've got little ones, pick up a set of plastic plates, which ensures you won't have broken dishes when it's your lil one's turn to offer a helping hand. Source: Flickr user jmrodri 7 / 7 2 1 4 0 0 Back to Homepage Read More ParentingDinnerFamily parenting 9 Signs You've Succumbed to Intensive Parenting 1 day ago For Those of You Who Can't Bear to Hear "Let It Go" One More Time . . . 1 day ago 9 Need-to-Have Tech Finds For Teens 1 day ago How to Fake a Good Night's Sleep 2 days ago The Five SAT Changes You Need to Know Now 2 days ago Celebs Who Wrote the Book on Parenting — Literally! 2 days ago Link Love Mom forced to stop feeding baby homemade formula — BabyCenter Blog The easiest ways to save on organic food — The Stir A look inside Fergie's second baby shower — Celebrity Baby Scoop Danielle Jonas debuts her baby bump — People Moms & Babies 7 light and fresh recipes to take you through Summer — FitPregnancy Does where you live affect your risk for PPD? — The Bump Where to find the best deals on school supplies — Real Simple Now this is how you announce a pregnancy! — HuffPost Parents
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save 38% $19.99 Converse Kids - Chuck Taylor All Star Ox (Little Kid) (Aruba Blue) - Footwear at 6pm.com 219 save 30% $63.00 UGG Kids - Classic Mini (Toddler/Little Kid) (Chestnut) - Footwear at Zappos 164
5-Year-Old's Attempt To Forge Mommy's Signature Is Definitely Frame-Worthy HuffPost Parents 3.4K Shares
Sneak a Peek at Jessica Simpson's Expanded Maternity Collection For Spring/Summer 2013 101 Reactions 1.5K Shares


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The Vizio VP503 is a 50" Plasma HDTV from Vizio's VP Series for 2008. The unit features a native resolution of 720p or 1080i and has a 15,000:1 contrast ratio to provide high definition graphics with vibrant color reproduction.
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It offers 1400 nits brightness, a 178-degree viewing angle, and ultra fast response times for blur-free images. The VP503 has dual built-in 10-watt speakers to provide accompanying stereo sound. It comes equipped with a variety of inputs including composite, component, S-Video, VGA, and four HDMI inputs. The VP503 has a suggested retail price of $1050 and comes with a 1 year limited warranty.
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member since November 11, 2009
But I will show you.
Comics By thegypsy
No comics.
Comics Assisted By thegypsy
No comics.
Comics Recomended By thegypsy
One big dysfunctional family of monsters, living in that part of the woods where those meddling kids tend to disappear...
A grotesque life story of a demon that eats other demons to get stronger.
Alicka and her little brother Winston are sent to Winkerkill Boarding School. The number one dumping ground of unwanted troubled teens. A miniature Gormenghast filled with bad seeds and black sheep.
The exploits of a socially-conscious weapons sales-orc on the world of Chirna.
It's about zombies. :D
The Dragon and the Lemur tells the story of two MALE lovers. It's a (mostly) YAOI webcomic, so be warned for the amounts of crappy romance and sex it has. RATED ADULT/MATURE, it had explicit sex of ALL sorts.
We've all been there: you go out and have a few too many, and the next thing you know, you're waking up in a gutter in some sort of alternate universe. S'ok, buddy. Happens to the best of us. Beware: contains lots of bad words and copious cross-hatchin
The story of a little transgender girl, her gender playful BFF, her family and her friends.
A surreal victorian era dream comic, that can be non-linear at times.
David has been known to be very grumpy, so has Wasso. Will they ever get along? Or...more?! The sequal to the yaoi WIRES, you do not need to read the first one to have this one make sense! -Nominated for Best Overall Comic of '08 & '09-
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Cross at 8:09PM, Nov. 7, 2010
Thanks for the Add :3
Raziel_X007223 at 10:33AM, May 30, 2010
Thanks for adding me as a friend!
that kid yellow at 11:01AM, April 25, 2010
np thnk u for the add also
DarkChibiShadow at 6:42PM, April 11, 2010
Aw no no no it's okay! Thank you so much, it did make me feel happy that people like my comics! I really appreaciate you ready my comics since I update a ton and then sometimes not and sometimes it's bad and sometimes it's okay, so I am really thankful you hang in there through all the ups and downs!
DarkChibiShadow at 6:59AM, April 8, 2010
Sorry but that's what haitus means. :c Sometimes comics I make just don't take off for me like I want them too. (But I have plenty of straight comics in the work) I'm sorry but sometimes I just want to work on stories I just want to work on.../guilty feeling/
Little Swan at 1:55PM, Dec. 16, 2009
Hey, thanks for adding me back :] Your profile seemed really interesting, so I hope you don't mind me adding you.
Sei at 1:26AM, Dec. 8, 2009
Oh, thank you for the unexpected friend add! D:
DarkChibiShadow at 1:02PM, Nov. 30, 2009
Ah, well more info is in the link I posted. Bascially it's just like writing a regular fic, so just- write a regular fic. (So not like dialouge and stuff that happens or drawings ahaha, unless you want to I guess!) That's all I really need to make it into something!
DarkChibiShadow at 8:05PM, Nov. 24, 2009
Hey! Thanks for the add!


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Ski Jump Landing Fail Win What looks like an epic fail turns into an epic win! 2/6/2012 12:00:00 AM 21,120
Halftime Dunk Fail This kid overshoots his jump and ends up dunking himself instead of the basketball. 11/1/2012 12:00:00 AM 44,872
Best Stupid Game Show Answers Ever Here's a massive compilation of some of the most retarded answers ever given on tv game shows. 10/18/2012 12:00:00 AM 24,786
Best News Bloopers of 2012 - Part 2 The second part of the news bloopers from earlier this week. 6/22/2012 12:00:00 AM 18,101
Cleaning Lady Vacuuming Fail hmmm, how come nothing is getting picked up? 5/21/2012 12:00:00 AM 15,472


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Artist: Bob Dylan
Album: Empire Burlesque
Genre: Rock
Well, I thought that the rain would cool things down
But it looks like it don't
I'd like to get you to change your mind
But it looks like you won't
From now on I'll be busy
Ain't goin' nowhere fast
I'm just glad it's over
And I'm seein' the real you at last
Well, I risk my neck for you
Didn't I take chances?
Didn't I rise above it all
The most unfortunate circumstances?
Well, I have had some rotten nights
Didn't think that they would pass
I'm just thankful and grateful
To be seeing the real you at last
I'm hungry and I'm irritable
And I'm tired of this bag of tricks
At one time there was nothin' wrong with me
That you could not fix
Well, I sailed through the storm
Strapped to the mast
But now the time has come
And I'm seein' the real you at last
When I met you, baby
You didn't show no visible scars
You could ride like Annie Oakley
You could shoot like Belle Starr
Well, I don't mind a reasonable amount of trouble
Trouble always comes to pass
All I care about now
Is that I'm seein' the real you at last
Ohh, yes I am
Well, I'm gonna quit this baby talk now
I guess I should have known
I got troubles, I think maybe you got troubles
I think maybe we'd better leave each other alone
Whatever you gonna do
Please do it fast
I'm still tryin' to get used to
Seein' the real you at last
Ohh yes I am
Writer(s): Bob Dylan
Copyright: Special Rider Music
Lyrics powered by www.musiXmatch.com
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Asacol HD
What is Asacol HD?
Mesalamine affects a substance in the body that causes inflammation, tissue damage, and diarrhea.
Mesalamine is used to treat ulcerative colitis, proctitis, and proctosigmoiditis. Mesalamine is also used to prevent the symptoms of ulcerative colitis from recurring.
Mesalamine may also be used for purposes not listed in this medication guide.
In This Section:
What is the most important information I should know about Asacol HD?
Mesalamine is used to treat ulcerative colitis, proctitis, and proctosigmoiditis.
Stop using mesalamine and call your doctor at once if you have severe stomach pain, cramping, fever, headache, and bloody diarrhea.
What should I discuss with my healthcare provider before taking Asacol HD?
You should not use this medication if you are allergic to mesalamine or to aspirin or other salicylates (such as Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others).
To make sure mesalamine is safe for you, tell your doctor if you have:
- a stomach condition called pyloric stenosis
- a history of allergy to sulfasalazine (Azulfidine)
- heart disease
- kidney disease; or
- liver disease
FDA pregnancy category C. It is not known whether mesalamine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
Mesalamine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
What conditions might Asacol HD treat?
Condition | Ratings and Reviews |
Crohn's Disease -- Maintenance |
Copyright 1996-2014 Cerner Multum, Inc. Version: 8.02. Revision date: 2013-05-15.
Asacol HD Side Effects
What are the possible side effects of Asacol HD?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using mesalamine and call your doctor at once if you have:
- severe stomach pain, cramping, bloody diarrhea
- fever, headache, skin rash
- chest pain, shortness of breath
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
- little or no urinating
- swelling, rapid weight gain; or
- bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds
Common side effects may include:
- mild stomach discomfort, gas
- flu symptoms, runny nose
- diarrhea, constipation
- headache, dizziness
- weakness; or
- joint pain
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Back to TopCopyright 1996-2014 Cerner Multum, Inc. Version: 8.02. Revision date: 2013-05-15.
Asacol HD Interactions
What other drugs affect Asacol HD?
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with mesalamine, especially:
- amphotericin B
- azathioprine or mercaptopurine
- pentamidine
- tacrolimus
- an antibiotic--capreomycin, rifampin, vancomycin
- antiviral medicines--acyclovir, adefovir, cidofovir, foscarnet
- cancer medicine--aldesleukin, carmustine, cisplatin, ifosfamide, oxaliplatin, streptozocin, tretinoin; or
- NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others
This list is not complete and other drugs may interact with mesalamine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Back to TopWhat should I avoid while taking Asacol HD?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Back to TopCopyright 1996-2014 Cerner Multum, Inc. Version: 8.02. Revision date: 2013-05-15.
Asacol HD Dosage
In This Section:
How should I take Asacol HD?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take mesalamine with a full glass of water.
Mesalamine can usually be taken with or without food. Follow your doctor's instructions.
Mesalamine extended-release capsules (Lialda) should be taken with a meal.
Do not crush, break, or chew a mesalamine tablet or capsule. Swallow the pill whole.
The extended-release capsule is specially formulated to release the medicine after it has passed through your stomach into your intestines. Breaking the pill may cause the drug to be released too early in the digestive tract.
The enteric-coated tablet has a special coating to protect your stomach. Breaking the pill could damage this coating.
Call your doctor if you find undissolved tablets in your stool.
Store at room temperature away from moisture and heat.
Back to TopWhat happens if I overdose on Asacol HD?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Back to TopWhat happens if I miss a dose of Asacol HD?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Back to TopCopyright 1996-2014 Cerner Multum, Inc. Version: 8.02. Revision date: 2013-05-15.
Asacol HD Reviews
Copyright © 2014 Everyday Health Media, LLC
About Drugs A-Z
Drugs A-Z provides drug information from trusted third-party Everyday Health partners and ratings from our members, all in one place. Cerner Multum™ provides the data within most of the Basics, Side Effects, Interactions and Dosage tabs. The information within the Reviews and FAQ tabs is proprietary to Everyday Health.You can browse Drugs A-Z for a specific prescription or over-the-counter drug or look up drugs based on your specific condition. This information is for educational purposes only, and not meant to provide medical advice, treatment or diagnosis. Remember to always consult your physician or health care provider before starting, stopping or altering a treatment or health care regimen.
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Author | Post |
AlucardsFate | #31 Subject: Or Posted: 09/19/2004 03:14:19 |
You know that the Chrono series was a cult popular series. It never really made it with the mainstream like Final Fantasy or Zelda did. Maybe they don't think a third game would profit outside of the Japanese market.
magusguy | #32 Subject: chrono break.... a concurative meh Posted: 09/19/2004 10:33:49 |
I don't think many games can live up to the standards of the past chrono series. And we can't say for sure if there really wasn't any japanese release of any other chrono game. For example, Fire emblem was popular in japan for almost a decade before we even knew about it. When marth and roy made an appearance in ssbm, the cat was out of the bag and nintendo couldn't say no to a u.s. release. Why they ever said no to any of them is beyond me, but... I'm getting off-topic. There is that new game coming out... it's got a strange name... Baten kaitos I believe... mebbe that'll be good.
AlucardsFate | #33 Subject: Baten kaitos Posted: 09/20/2004 21:02:52 |
I saw a commercial for that game. How can you be sure that its a sequel to the Crono games. Its not, I think that it shares the same designers as Crono Cross but thats it. I think.
InfernoMan | #34 Subject: Curiousity Posted: 09/23/2004 18:40:12 |
Did anyone hear anything about "Chrono Break", and when (or if it is coming out? cuz i thought i did.
AlucardsFate | #35 Subject: Dude... Posted: 09/23/2004 21:26:18 |
Check the last couple of pages worth of posts to learn about it.
LiquidMoon | #36 Subject: Guess I'm not alone Posted: 09/29/2004 00:14:48 |
Thought I was the only one that loves the Chrono Cross game, guess I'm not alone. I'm excited to finally see there are others who appreciate this great game.
AlucardsFate | #37 Subject: No, your not alone Posted: 09/29/2004 22:14:12 |
We are here to preach the word of this highly unapreciated series. I absolutley love the Final Fantasy series, but both of the Chrono games easily top any one of them. (Even FF7)
cloudxsamura... | #38 Subject: i just started Posted: 10/04/2004 17:06:40 |
i just started this 1up account, and the first club that caught my eye, was this one. i love chrono trigger/cross. they have to be some of the best rpgs ever made to date.
reality322 | #39 Subject: CHRONO Posted: 10/04/2004 18:39:46 |
Chrono Trigger is my favorite game.(had to get that out.lol)Has anybody heard anything about the part 3?
cloudxsamura... | #40 Subject: chrono break Posted: 10/04/2004 21:10:24 |
check out this poster for the game, its all i could find.....
http://www.rpgamer.com/games/chrono/break/propaganda/cbreak1.jpg also, check out these http://www.rpgamer.com/games/chrono/break/breakss.html |
AlucardsFate | #41 Subject: Come on guy... Posted: 10/04/2004 22:10:04 |
...you can't tell that those are fake?! Come ON! The screenshots have Serge in them! Not even an older Serge with PS2 calibur character models! Its the PS1 character models!
Lo/Rez | #42 Subject: Also Posted: 10/05/2004 00:44:26 |
most of the other screenshots are obviously from FFXI
AlucardsFate | #43 Subject: Good Eye! Posted: 10/05/2004 21:12:56 |
I've never played FFXI, so thanks for catching that!
chronotrigge... | #44 Subject: Hello everyone as you can tell I'm a huge chrono trigger fan, Posted: 10/06/2004 22:23:17 |
I normally post at another Chrono board but its pretty dead with the lack of attention Square has been giving the Chrono series.
LiquidMoon | #45 Subject: Welcome Posted: 10/07/2004 02:10:47 |
Love your avatar CHRONOTRIGGER.
~ |
AlucardsFate | #46 Subject: Avitar? Posted: 10/08/2004 00:44:01 |
What is an Avitar? Why don't I know?
Terry Bogard | #47 Subject: sup Posted: 10/10/2004 15:09:22 |
Rank: Button Masher Joined: 09/24/2004 Post Count: 0 Offline |
hey whats up Im new and i reeeeeaaaaaaly hope a new chrono game shows up also anyone heard of an actual date that the ff7 movie comes out?
chronotrigge... | #48 Subject: No release date yet, Posted: 10/11/2004 11:35:32 |
Expect it sometime next year, hopefully early next year.
Terry Bogard | #49 Subject: ff7 Posted: 10/12/2004 19:50:57 |
Rank: Button Masher Joined: 09/24/2004 Post Count: 0 Offline |
yea i defineatly hope that it comes out early next year.
DrEaMeRsBlAz... | #50 Subject: chrono game Posted: 10/18/2004 15:15:48 |
Rank: Achievement Whore Joined: 10/18/2004 Post Count: 0 Offline |
a new chrono game!!! that would be cool, i think i heard of one...
halochief_90 | #51 Subject: 100th Club!!! Posted: 10/19/2004 19:00:49 |
This is the 100th club I have joined and I thought I would join a club with some of the best games worshiped on it. I am quite happy I realized I had joined 99 clubs before I made my 100th club based on a game/series that is just good instead of great. Ths club being great!
AlucardsFate | #52 Subject: Geez Guy... Posted: 10/20/2004 00:15:45 |
...100 clubs!? I only have 28 clubs and it takes near an hour to post in them all. (I prefer to be as loud in each one as possible) How much time do you have?!
Masamune | #53 Subject: Chrono... Posted: 10/20/2004 03:06:29 |
Break. The game you heard of was probably Chrono Break. I think Square lost the rights to that name though, so expect it under another. I hope we get some news about it soon...
AlucardsFate | #54 Subject: Ya know guy... Posted: 10/21/2004 01:20:20 |
...I've been saying I hope ever since Chrono Cross came out and I have lost any and all hope.
lionsmane81 | #55 Subject: SWEET Posted: 10/24/2004 15:26:49 |
Chrono kicks ass....so basically I just said time kicks ass..oookay. I'm gonna go now. ^.^
AlucardsFate | #56 Subject: Uh... Posted: 10/25/2004 00:26:09 |
DrEaMeRsBlAz... | #57 Subject: lol Posted: 10/29/2004 10:37:36 |
Rank: Achievement Whore Joined: 10/18/2004 Post Count: 0 Offline |
they shoud remake chrono trigger into 3d!!! lol... lame i know
AlucardsFate | #58 Subject: Yeah....I suppose.... Posted: 10/31/2004 00:18:56 |
...They could...They should make a new one though.
reality322 | #59 Subject: 3D chrono Posted: 11/02/2004 09:55:02 |
I think they should keep da 2D look. If they make it into 3D it will look like Final Fantasy. There's nothin wrong with F.F. but i just think they're characters look alot alike.
Masamune | #60 Subject: there was Posted: 11/04/2004 14:39:24 |
a PC chrono trigger adaptation in the works by a group of chrono fans. it was 3d, dargon ball z budokai 1 style. It actually looked pretty goood, but then square went and sent them a "cease and desist" order for using thier product without consultation.


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DON CARTER STATE PARK, GADescriptionDon Carter is Georgia's newest state park, as well as the first state park on 39,000-acre Lake Lanier. Situated on the north end of the reservoir, the park offers outstanding recreation for water lovers. Guests can stay cool at a large, sand swimming beach with bath house. Boat ramps provide quick access to the lake, while a paved, multi-use trail welcome hikers and bikers to explore the hardwood forest.This new park offers several choices for overnight getaways as well. Two-bedroom cabins are perched on wooded hillsides near the lake. One campground accommodates RVs, while another camping area is reserved just for tents and hammocks. The park is named in honor of real-estate executive Don Carter who served on the Georgia Department of Natural Resources board for 29 years and worked to establish Lake Lanier's first state park. Recreation:Swimming. Facilities:Cottages Nearby Attractions:Unicoi State Park Services & Amenities:
Alerts and Important Information Parkpass is required for all vehicles. ParkPass fees: 1-12 passenger vehicles $5 per day or $50 annual ParkPass; 13 - 30 passenger vehicles $30 per day or $75 annual ParkPass; 31 or more passenger vehicles $70 per day or $250 annual ParkPass; Georgia active duty military/veterans $3.75 per day or $37.50 annual ParkPass. Daily or Annual ParkPass is available at the park office. Overnight guests pay only one fee for the duration of their stay. Annual Parkpass can be purchased by calling (770) 389-7401, Reservation Administration. Park Rules and Regulations: Rules and regulations are posted at site offices and must be observed by all guests and their visitors. Smoke-Free Facilities: Please be advised that smoking is prohibited in all enclosed facilities, including buildings owned, leased, or operated by the State or local governing authorities. This includes all lodge rooms & facilities, park cottages, group shelters, group lodges, group camps, Chattahoochee Bend Adirondack Campsites, Mistletoe Camper Cabin, Seminole Treehouse Camping, Watson Mill Log Cabin Bunkhouses and yurts camps. Georgia Smoke-free Air Act of 2005. Pets: Pets are welcome at state parks and campgrounds if leashed (no longer than six feet) and accompanied by the owner at all times; however, they are not allowed in or around historic sites, lodges, group camps, swimming areas, or some trails at Panola Mountain and Tallulah Gorge. Pets are allowed only in select cottages with advance reservations and a fee. Kennels are not available. Owners should clean up after pets. Intoxicants: Consumption or use of alcoholic beverages or intoxicants is unlawful in any public-use area. Campfires: All campfires must be kept in designated areas such as a fire ring. Never leave a campfire unattended. Smaller fires with coals (rather than large flames) are better for campfire cooking and toasting marshmallows. Weapons: Bows and arrows, explosives, fireworks, slingshots, fishing spears or any device that discharges projectiles by any means is prohibited. Firearms must be unloaded, cased and stored, unless a person possesses a valid weapons-carry license for a firearm that is valid in Georgia. A person possessing a valid weapon-carry license to carry a firearm valid in this state may carry such firearm on Georgia State Parks and Historic Sites, except on sites where carrying such firearm is prohibited by federal law. Firearms except those that are unloaded, cased and stored are not permitted on sites that are leased, federal Army Corps of Engineers property, including: Red Top Mountain Seminole George T. Bagby Florence Marina Tugaloo Hart Bobby Brown Richard B. Russell Elijah Clark Mistletoe Reciprocal Firearms Agreements Some states have reciprocal firearms agreements with Georgia, and their citizens may possess a firearm as long as they possess a valid weapons carry permit from their respective state. These include: Alabama, Alaska, Arkansas, Arizona, Colorado, Florida, Idaho, Indiana, Iowa, Kentucky, Louisiana, Michigan, Mississippi, Missouri, Montana, New Hampshire, North Carolina, North Dakota, Oklahoma, Pennsylvania, South Dakota, Tennessee, Texas, Utah, Wisconsin and Wyoming. Collecting: All wildlife, plant life, driftwood, artifacts and any other natural or man-made features are protected and may not be disturbed or removed. Please leave wildflowers for other visitors to enjoy. Possession of metal detecting equipment is prohibited. Motor Vehicles: Park roads are public roads. All vehicles are subject to license safety requirements and regulations of the Georgia Department of Public Safety. ATVs are not allowed in state parks. Getting There:GPS Info. (Latitude, Longitude):34.38972, -83.75278 34°23'23"N, 83°45'10"W 85N to I-985N toward Gainesville to Exit 24 toward US-129/GA-369. Follow US-129N to GA-284N, Clarks Bridge Road. Turn right on Clarks Bridge Road. Follow to North Browning Bridge Road, about 6 miles. Turn right at North Browning Bridge Road. Contact Information:Mailing Address:DON CARTER STATE PARK500 North Browning Bridge Road Gainesville GA 30506 Phone Number:Information: (678)450-7726 |


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I understand from today's announcement that the kindle fire device will run on Android.
Thanks, Juergen
When will Adobe's tools support Kindle Fire? A date would be very helpful and some advice about the hardware limitations. In the light of these limitations (and its currently smaller form factor) we may have to create a new edition of each publication specifically for the Fire. It may have been unrealistic but my clients assumed that ADPS would already be able to export to this format and where surprised when I told them that I didn't know when it would.
Viewer Builder 1.7, released last thursday supports kindle fire.
Verstuurd vanaf mijn iPod
Op 10 nov. 2011 om 10:40 heeft "Graham Davis" <firstname.lastname@example.com<mailto:firstname.lastname@example.com>> het volgende geschreven:
Re: Kindle Fire Support?
created by Graham Davis<http://forums.adobe.com/people/Graham+Davis> in Digital Publishing Suite - View the full discussion<http://forums.adobe.com/message/4017842#4017842
I am confused Bob. Klaasjan Tukker says the Viewer Builder is already able to generate an App for Kindle Fire but we don't have a Content Viewer on the device that we can use to preview and test it!
do you know what the resolution dimensions (for creating a new document in InDesign) are for Kindle Fire?...I too would like to start building demo .folios and test these.
Is there a document that states what DPS interactivites are supported/not supported for Kindle Fire?
thanks in advance.
Tom Davis
Klaasjan is correct. You can use Viewer Builder to create a custom viewer app that you can submit to Amazon appstore. You can also sideload that .apk file onto your Amazon Fire and test your folios (1024x600) that are published as public. The same DPS limitations that apply to Android devices also apply to the Fire -- no inline videos, no PDF pinch/zoom, HTML limitations, etc.
Bob, I'm running into a snag with the sideloading process. I was able to sideload and install the viewer APK file on my Kindle Fire, but it repeatedly crashed on launch. We worked with Adobe Support over the weekend and their recommendation is to upload the APK to the Android Market (or, I assume, the Amazon Appstore) and activate it. But we aren't yet ready to publish -- we just want to test the viewer and folios locally.
Can Adobe make its existing Android viewer APK available for download on the DPS website? Or post it on the Appstore?
Any help would be appreciated. I've had two opportunities to demonstrate the Kindle Fire app to clients over the past week and have had to make excuses. This is getting frustrating.
Amazon and Adobe are still sorting out the Amazon Appstore details. Currently, there is no Adobe Content Viewer available in the Amazon Appstore -- one should be submitted today or tomorrow -- and I recently learned that any .apk file you sideload to the Fire won't work because Amazon hasn't certified it yet. My understand is that you need to submit the .apk file to Amazon, Amazon wraps it and sends it back to you, and then you sign it and can test it. Amazon calls this "up-down-up signing."
Thanks, Bob, for the great information. I understand that there are several players here and many moving parts. I'll watch for that viewer on the Appstore.
BTW there seems to be a lot of interest in the Kindle Fire. Clients who have never expressed any interest before in Android want to be on this platform as well as the iPad.
Apologies to Juergen for hijacking his post.
Amazon is reviewing the Adobe Content Viewer. It will be available when they approve.
Amazon is currently rejecting any viewer app that gets submitted because the viewer points to Android Market if AIR is not installed. (AIR is always installed on a Fire but may not be on an Android device.) They obviously don't want us to point to the Android Store instead of the Amazon Appstore. The team created a different version of the Viewer Builder that points the appropriate store if AIR isn't installed. It should be posted soon. I used the new version of the Viewer Builder to submit my DPS Tips app again to Amazon. Haven't heard from them yet.
just use new Viewer Builder 1.7.0-RC_2, create a new viewer for Android and set Market "App Store Amazon for Android", sent to .apk to Amazon.
Bad luck, once again answer from amazon :
Your recent submission of Le Magazine AutoTrends is pending due to the following reason(s):
Through our testing process, we found that your app requires Adobe AIR to function. Customers that do not already have Adobe AIR installed will be prompted to download the app. To point users directly to the Adobe AIR page on the Amazon Appstore use the following Download URL: http://www.amazon.com/gp/mas/dl/android?p=com.adobe.air. (Currently your app links to the front page of the Appstore, not directly to Adobe AIR in the Appstore.)
Any idea to fix this error ?
mlipson - You should download "Viewer Builder 1.7.0 RC-2." If that's not downloading, you may want to clear the cache in your browser, remove Viewer Builder, and download again.
Steve - I haven't heard anything from Amazon. As I mentioned, my understanding is that we made a fix to the Viewer Builder on our end assuming that a fix would be done on their end. I heard from an Adobe tester that Amazon has not made the appropriate redirect on their end, so the .apk file is still pointing to the Android Market. That will cause the submitted viewers to get rejected. I pointed this out to Amazon and haven't heard back. I'm wondering if the stakeholders are gone for the holidays -- I'll be leaving myself for a couple of weeks, just checking email occasionally -- but I'm hoping the issue will be resolved soon. I'll let you know when I get any news.
Thanks Bob.
I did download the RC-2...although once installed I checked the release # and saw it was still 1.7.0.
I was sort of expecting a 1.7.1 or other increment.
I will go ahead and submit a new VB app to Amazon today...and advise of it gets approved.
BTW - thanks for posting the "Updated Viewer Builder Announcement" at the top of the forum - very helpful.
Has anyone been able to successfully submit a DPS app to the amazon app store ?Using the 1.7 RC2 version of the builder still causes a reject from amazon.
Your recent submission of RSNA News is pending due to the following reason(s):
Your app has failed a test case. Bug Description: The application crashes consistently. The user discovered that, when attempting to download and install the August 2011 edition of the RSNA News Journal, the application froze during the installation process before crashing and returning the user to the device's home menu with no error message. Steps to Reproduce: 1. Download and install the application on the target device. 2. Launch the application to the main library menu. 3. Select the "RSNA News August 2011" edition to download and install. 4. Note that during installation, the application progress bar stops briefly before the application crashes and the user is returned to the device's home screen. OS/Device(s)/Form Factor: Samsung i800 (Galaxy Tab) A SCH-I800.EH01
Please correct the issue(s) we found with your app submission so we may continue working to get it in the Appstore.
John -
I just received essentially same rejection
paradise valley v 184.108.40.206.34817 exhibits consistent, reproducible instances of force closing when tested for compatibility on Kindle Fire. Currently the app Force Closes on launch. A logcat file has been attached to this email to assist you in troubleshooting the problem.
I had not sideloaded the 1.7 RC2 app onto my Kindle prior to re-submitting to Amazon for approval. I simply re-created the app in Viewer Builder then re-posted to Amazon. Now that I have loaded the RC2 build on my Kindle, it does in fact crash almost immediately after launch. It goes through the splash screen then force quits.
btw - Amazon has updated my Kindle OS to 6.2.1 if that is helpful as well.


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The shroud of Turin is in the news again because for the first time in twenty years it is now on display for two weeks. On May 28, 1998 the Pope showed up to venerate the relic. (In the year 2000 it will again be on display.) Since it last made headlines there have been interesting developments.
Tens years ago some swatches of the linen of the cloth were given to scientists to be radio-carbon dated. The three independent laboratories doing the testing unanimously agreed - the shroud dated to 1260-1390. This seemed decisive - the shroud was a fraud in that it could not possibly be the burial cloth of Jesus. The scientists later cited odds of a trillion to one that they could not be wrong.
However, Time Magazine of April 20, 1998 ran a cover story on the shroud and revealed that possibilites had since arisen that meant, to the contrary, the shroud could possibly be real. One reason was:
Tainted samples? The strongest and most obvious technical critique of the radiocarbon dating, springing from an indisputable weakness in the testing procedure, is that since all three labs' specimens came from a single swatch of cloth, all would be affected if the swatch were atypical or contaminated. The mantra for this position, quoted fervently by shroud proponents who might otherwise have little to do with one another, is the "the tests could have been precise without being accurate."
Though not mentioned in the article, there exist centuries old pictures showing human beings holding the cloth in just the area being tested! A second possiblity for error mentioned by the Times article is:
A deceptive coat of Varnish? One challenge to the readiocarbon dating that has received a good deal of publicity is that of Dr Leoncio Garza-Valdes, a San Antonio, Texas, pediatrician with interest in microbiology and archaeology. In 1983, while examining a Mayan jade artifact that art experts claimed was a recent forgery, Garza-Baldes discovered that it was covered by a lacquer-like coating produced by bacteria. Since it also had traces of ancient blood on it that should have been datable by the radiocarbon method, he took it to the University of Arizona dating lab, where scientists scraped off a sample of the natural "varish" as well as the blood underneath it. They came up with a date of about AD 400 - definitely not modern, but still 600 years younger than the carvings's style suggested. Several years later, when the three labs, the University of Arizona among them, produced their wet-blanket dates for the Turin shroud, a possibility flashed through Garza-Valdes' mind. What if the shroud too had a "Bioplastic" varnish - and the labs had been fooled into decreeing an object hounger than it actually was?
Later Garza-Baldes visited Turin with microscope in hand and was allowed to examine a piece of the shroud. "I knew immediately", he says, "that the coating was there." Futhermore, this coating - which is transparent and thus invisible to the naked eye - cannot be removed by the conventional cleaning methods of most readicarbon labs. Today, this is still a valid possible objection but it has not been resolved. The church has recalled all outstanding samples of the cloth.
The Times article notes favorably The Blood and the Shroud: New Evidence That the World's Most Sacred Relic is Real by Ian Wilson. When one reads this entire book, the total weight of all kinds, when all placed together on the scales, makes it highly likely that this is the shroud of Jesus.
But how does this relate to Theosophy? Blavatsky asserts that there actually was an individual around whom the biblical story of Jesus has been fashioned. However she notes that this "Jesus" had a different name, was born at a different time, was not fully Jewish, and that the current biblical version is a stubstantial distortion of the truth. Yet he existed, was an initiate and a great teacher. Provocatively, Blavatsky predicts that the figure of Jesus will loom larger in future centuries.
When all the details are considered we think it possible that this shroud could be part of the evidence that will cause "Jesus" to loom larger in future centuries.
One further note that we cannot fully expound upon here. The Theosophical story of Jesus is complicated. But from studying it at some length, we feel that the Theosophical version of Jesus is compatible with this shroud being genuine. And we rather think it is genuine. At a later time we may write more on this subject.
Certainly this issue, now before the public, can have long term repercussions on the belief system of the times.
R.C. May 29, 1998


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PIAAC › Public Data & Analysis
The data collection for the Survey of Adult Skills (PIAAC) took place from 1 August 2011 to 31 March 2012 in most participating countries. Around 166 000 adults, representing 724 million adults aged 16 to 65, were surveyed in 24 countries and sub-national regions in the official language/s of the countries. »Read more about the Survey and discover some sample items in literacy, reading components, numeracy and problem-solving.
The International Data Explorer (IDE) allows you to create statistical tables and charts to explore adults' (16-65 years of age) performance in literacy, numearcy, and problem solving in technology-rich environments. Data can be analysed by country as well as in relation to demographic characteristics, social and linguistic background, education, use of skills and employment status.
Public Use Files containing individual unit record data in SAS and SPSS format are available for downloading for each of the countries participating in the Survey of Adult Skills other than Australia. These contain both responses to the background questionnaire and the cognitive assessment. Full documentation of the contents of the files is provided. Please note that these files are primarily designed for use by researchers and data analysts. The files are also large and may take some time to download. To access the Australian Public Use File please write to: email@example.com
Public Use Files (PUF). Please note that these files were updated on 7 November 2013. Information about the changes can be found here.
PIAAC Data Analysis Manual (SAS®, STATA®)
SAS® Macro (version 1.2). Please note that this file was updated on 18 December 2013.
STATA® Macro (version 1.2). Please note that this file was updated on 9 January 2014.
Technical Report of the Survey of Adult Skills (PIAAC)
Data compendia - Background variables. Please note that these files were updated on 13 November 2013.
Data Compendia - Cognitive variables
The compendia are sets of tables that provide categorical percentages for both cognitive and background items. The purpose of the compendia is to support PUF users so that they can gain knowledge of the contents of the PUF, and can use the compendia results to be sure that they are performing PUF analyses correctly. Note that due to the design of the cognitive assessment, comparisons of the cognitive item statistics provided in the compendia across countries for reporting purposes may not be appropriate.
International Adult Literacy Survey (IALS) and the Adult Literacy and Life Skills Survey (ALL)
Public use microdata files containing data from the International Adult Literacy Survey (IALS) and the Adult Literacy and Life Skills Survey (ALL) can be accessed from Statistics Canada using the following links.
International Adult Literacy Survey
Adult Literacy and Life Skills Survey
International Adult Literacy Skills Survey (Canadian data from ALL)
These files contain results for literacy (IALS and ALL) and numeracy (ALL) on the same scales as the results from the Survey of Adult Skills (PIAAC). The process for linking results from the Survey of Adult Skills (PIAAC) and those from IALS and ALL is described in the Technical Report of the Survey of Adult Skills.
The International Database (IDB) Analyzer facilitates the analysis of data from the Survey of Adult Skills (PIAAC). It creates SPSS code that can be used with SPSS to conduct statistical analyses, taking into account the complex sample structure of the databases. The software allows you to combine data from different countries for cross-country analysis and to select specific subsets of variables. It provides several different procedures for analysis, such as the computation of means or percentages of any background variable of interest for a whole country or subgroup within a population.
The Education GPS will allow you to keep up to date with the latest OECD data and research on education and skills. The OECD Education GPS brings the world of education to your fingertips and provides you with easy access to the OECD's wealth of data on education policies and practices.
The links below will allow you to download all the figures and tables included in the OECD Skills Outlook 2013: First Results from the Survey of Adult Skills. The webpackages also include data tables for other skill domains referred to but not examined in the report as well as some additional data. The package consists of Excel workbooks that can be viewed and downloaded by chapter. These files were updated to include data for France and the Russian Federation and published on 14 January 2014.
Overview: Key Findings from the Survey of Adult Skills
Chapter 1: The Skills Needed for the 21st Century.
Chapter 2: Proficiency in Key Information-Processing Skills among Working-Age Adults.
Chapter 3: The Socio-Demographic Distribution of Key Information-Processing Skills
Chapter 4: How Skills Are Used in the Workplace
Chapter 5: Developing and Maintaining Key Information-Processing Skills
Chapter 6: Key Skills and Economic and Social Well-Being
Annex B: OECD Skills Outlook 2013 additional tables
Additional Tables (Minimum, mean, median and maximum values for hourly and monthly earnings by deciles).
For questions contact: firstname.lastname@example.com