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31761 Camino Capistrano
San Juan Capistrano, CA 92675
San Juan Capistrano
Getting there ›
$30 and under
More Details ›
RokPrime Details
Dining Style:
Casual Elegant
(949) 236-6669
Hours of Operation:
Open Daily at 11 AM
Lunch & Dinner Service
Payment Options:
AMEX, Discover, MasterCard, Visa
Steakhouse, Contemporary American, American
Executive Chef:
Dustin Houston
Dress Code:
Casual Dress
Accepts Walk-Ins:
Additional Details:
Banquet/Private Rooms, Bar Dining, Bar/Lounge, Counter Seating, Entertainment, Farm to Table, Full Bar, Gluten-free Menu, Happy Hour, Non-Smoking Restaurant, Patio/Outdoor Dining, Personal wines welcome, Personal wines welcome (corkage fee applies), Private Room, Takeout, View, Wheelchair Access
We do special events and catering throughout the year. Please call 949.236.6669 and let our Executive Chef, Dustin Houston, prepare a menu and plan that fits your needs.
Private Party Facilities:
We can customize a unique menu for any event and accommodate private parties of 8 to 20 on a daily basis. We can also offer the entire facility for up to 85 people at an additional cost. Call 949.236.6669 anytime to schedule a private tour.
Private Party Contact:
John Sickler (949) 236-6669
Amazing live music throughout week! Call 949.236.6669 for schedules.
Special Events & Promotions:
Coming Soon
Getting there
Cross Street:
Ortega Hwy and Camino Capistrano
Public Transit:
Steps away from the historic San Juan Capistrano Train Depot and the Historic Mission San Juan Capistrano.
Public Lot
Parking Details:
You may park on the street (Camino Capistrano) OR directly behind the restaurant in the free public lot OR directly next to the train depot and movie theatre garage. All parking is FREE to the public.
A word from RokPrime
RokPrime is located across the street from the historic Mission in downtown San Juan Capistrano. We serve only Prime beef, chops, seafood, and poultry. All of our proteins are naturally fed and raised.
No hormones. No antibiodics.
Our steaks and seafood are cooked on an ultra
hot lava Rok heated to 750 degrees and using only salts and minerals minded from the Himalayan mountains. This method of cooking the steaks creates a flavor and juciness you won't find anywhere. We deliver the best steak in Orange County.
In addition to our Prime steaks and seafood we offer a menu of signature
sandwiches and burgers, as well as from scratch soups and salads.
Foodspotting photos
See all photos >
Awards voted by OpenTable diners
Diners' Choice Winner
Diner Reviews
Had a great time at Rok Prime! Amy
(Adams) was an excellent server. She made our girlfriend's birthday very special by even displaying a Happy Birthday board! Very sweet! We all ordered the Waghu flat steak...absolutely delicious! Also there is a great wine selection available & very generous pours! Definitely worth the moderate pricing. Looking forward to going back very soon!"
Dined on 3/4/2014
The restaurant was very
accommodating to a mobility challenged guest and the service was excellent! Wonderful cocktail list with unique creations. Get there early and enjoy the happy hour! The small plates were delicious! We sampled the lamb lollipops, truffled fries, lobster stack, pancetta wrapped prawn skewers, grilled artichoke, jumbo onion rings and mac n' cheese. We'd recommend any of these dishes and would order them again! We dined on the Rok ribeye medallion steak (unique presentation; tender and delicious...not slathered in butter but with unusual dipping sauces), the scallops (numerous and tender; delicious), Pan seared Miso sea bass (light and flakey; very tasty) and the Rok seared pork chop (huge but very tender and tasty!)."
Dined on 2/27/2014
Loved the decor of this
restaurant...not what we expected at all. Ordered the Filet served on the hot rock, even though the reviews were a little mixed. I thought it was a great idea. I was able to basically cook the steak to the exact doneness that I was looking for. I would go back."
Dined on 2/22/2014
The service was great until it was
time for the check. It took a good 15 minutes to get my check once requested. The server took a quick drink order from the table behind us then went to the table on the other side of us. It was a 6 person party that were loud and took up a lot of time from the server. She just could not get away from this group. The table behind us was so mad they also walked out. They went to the front disk and another server had to come over and trake care of them. This other server also had to bring my check. Other than that the food was GREAT and was server was also great at reviewing the menu and how the rock cooking worked"
Dined on 2/14/2014
they loved the total experience.
Our server AMY did an excellent all around job."
Dined on 2/8/2014
We met some very special long-time
friends for dinner at Rok Prime. It was a very nice meal. The novelty of the lava rock cooking technique was a fun twist. The risotto could have been smoother and a little tastier. Overall, a very pleasant meal."
Dined on 1/25/2014
Went for the first time since we
had a Christmas gift card. Had small filet and sea scallops, and a wedge salad. Filet, although $30, was tasteless piece of cardboard. We had ordered the steak rare, and cooked is slightly more on the table rock (novelty for RokPrime way), and even though it was med rare, the steak had no flavor. Potatoes were mediocre. Sea Scallops ($28) were overcooked. The side veg was tasty. Wedge Salad was lacking on the bacon pieces and lettuce was all core. Bread-a couple warmed up rolls from Costco. All in all we loved the interior decor, staff was friendly, but we won't be back even with a free gift certificate. Disappointing!"
Dined on 1/16/2014
Upon arrival, we were seated
immediately. Our server was right behind us with menus and asking about drinks. After we ordered, there was a 20 minute wait before drinks were served by a different server. We then waited at least 20 more minutes for someone to take our food order. Our food was delivered right away. Then, another wait for our server to attend to us. My husband's meal was missing a side. The server questioned him three times if he was sure he did not receive the side! Finally, a different server arrived with the missing side. After our desert order, our server disappeard for at least 25 minutes before she returned. At the time of our meal, there were only one more party in the restaurant. We were there for 2 hours!"
Dined on 1/12/2014
Overall, all four diners had great
food and enjoyed the experience. The Wagyu skirt steak served on the rock was very tender and flavorful. The lobster stack with avocado appetizer was also a favorite. We also ordered the roasted corn side dish and it complemented the meal well. The vegetables served with the entre were a very small portion, so I would suggest another side if you are a big eater. I recommend this restaurant."
Dined on 1/11/2014
The waiter took our drink orders,
but forgot to enter the order. He comes back to apologize 15 minutes later - he said he was doing 'double-duty' as the waiter tonight. He brings me my wine, and proceeds to bring us an appetizer (on the house). The service was impeccable after that. The waiter 'regained' his tip. The food is a bit bland - hence the sauces to dip the food in. The cuisine is a bit 'gimmisky' - as they bring food that is 'cooked rare' to the table. You then 'cook' the meat to your liking on a 'hot round stone' that they place in front of you. It reminds me of 'Ishi-yaki' (Japanese cuisine. It literally means 'cooking on a stone'. I guess this is the Americanized version of that. I'll definitely be back to try this place again."
Dined on 12/29/2013
Unfortunately we didn't end up
having dinner, and steak seems to be what they are known for, but we did have appetizers, a salad and a couple of drinks. Everything we had was above par and the service was excellent. Parking is a bit tricky though, so keep an eye for an available spot!"
Dined on 12/27/2013
The beef was amazing - incredibly
tender and tasty. Loved all the sauces, but it really didn't need any enhancement. Rick cooking makes for a fun experience. Wish I lived in the area to go, again."
Dined on 1/2/2014
Way too expensive for the quality
and portions. Very average for 5 star price and service is unbelievably bad considering, Overall very disappointed and won't be back."
Dined on 12/31/2013
Rok Prime serves their steaks on
your personal 'hot rock' sizzling away your steak so that you can continue to cook it to your perfection. Loved it! Also highly recommend their "Bartender's signature" chocolate martini. To die for!"
Dined on 12/28/2013
For the price I would rather go to
Mastro's but lunch is a good value and on a travelzoo deal its worth coming to dinner. I always end up upgrading anyways and spending more."
Dined on 12/22/2013
We had a great meal! It was fun to
cook our meat on the rok. The restaurant was beautiful and the service was wonderful. The only complaint I have is that our booth had rips in the upholstery. We paid a lot for our dinner and thought that was a bit odd. Otherwise, a great restaurant. We will return!"
Dined on 12/19/2013
We had 6:30 reservations and were
seated promptly. Our drink order was taken right away and we were given time to talk. My wife ordered a wedge salad and a small filet. I ordered a wedge salad and center of a ribeye. The food was very good, but a little pricey for the area. The service was excellent"
Dined on 12/13/2013
My family dined here on
Thanksgiving and had a wonderful food and service experience! The menu was well thought out and delicious, and the food of high quality. We plan to return with friends to enjoy a steak dinner!"
Dined on 11/28/2013
This was our first time to
RokPrime and we loved everything about the restaurant . The food, ambiance, waitress, bar tender we loved our steak coming out on lava rock. We just got back from Hawaii where lot's of lava rock is all around and it just brought us back to our trip. Thank you for a great experience absolutely delicious! We are already planning our next date to RokPrime with friends."
Dined on 12/6/2013
Had a great time at Rok Prime. The
Porterhouse was cooked and seasoned perfectly. No need for sauces at all. Very tasty dressing on the Caesar. Best of all was our server. Amy was personable, made good recommendations, and helped make it a very special evening."
Dined on 12/3/2013
I took my family there for the
first time on (six of us) Thanksgiving and was pleasantly surprised with all aspects of the experience. A professional waiter, excellent food preperation/presentation/flavor (several 3-course alternatives to choose from), nice atmosphere at a reasonable price. There is free 3 hour parking in the nearby structure. The meal was comparable or better than many other well known Steak and Seafood restaraunts. We all left saying to each other how great it was."
Dined on 11/28/2013
About 2 years ago we were walking
down the street in San Juan Capistrano. RokPrime had just opened. There was a woman sitting outside the restaurant telling people about the lunch special. My wife and I went in to give it a try. The food was terrific. We liked it so much we brought a friend back and even our son. We truly enjoyed the atmosphere. The unique use of hot rocks to cook your steak was amazing. Since then we have been back a number of times. Always a great place to eat. This evening the service was so poor it took us easily 20 min between courses. My wife's dinner was overcooked. My partner could not get oil and balsamic vinegar without asking 3 times. Although everyone was nice, it was like we were an afterthought."
Dined on 11/26/2013
We vistied RokPrime for the first
time and were very impressed with the food and service. From drinks to appetizers and finally to entrees, everything was done very well and tasted great. The servers were very attentive and upbeat. They have a large outdoor patio which is currently closed, but looks like it would be nice for a summer dining experience. The decor is a mixture of spanish and country french. We will definitely be back for more."
Dined on 11/23/2013
My wife and I ate at Rok Prime for
the first time and we really enjoyed all aspects of the dining experience. The decor is funky and unique and matches the awesome background music that was playing coffeehouse style hits all night long. The food came out fresh and tasty, we particularly enjoyed cooking our own steak on a 750 degree rock. This allowed me to have medium steak and my wife to make medium well steak at the same time. The salad was very good and we tried two side dishes that were both delicious. Highly recommend this to anyone looking to go out for a nice dinner in South OC."
Dined on 11/22/2013
Food, Service & Bartender were the
best... They made a special occasion truly a night to remember. Great overall experience."
Dined on 11/15/2013
This is one of the best
restaurants in the OC. The meat is always fresh and service is beyond compare. I highly recommend this restaurant."
Dined on 11/16/2013
We booked RokPrime for our
anniversary and walked in to them giving us an anniversary card! The ambience and decor were really nice, service was great and very informative. Food was excellent and the 'rok' is really fun and interesting. We'd go back any time, especially for a special occasion."
Dined on 11/16/2013
I love the way they serve the
steaks on a hot rock rare so it can be cooked to you own peronal satisfaction and taste"
Dined on 11/9/2013
great place, we sat on the patio
for dinner. Had the filet, it was a terrific cut. I recommend having it served with the cooking stone, it was a great experience. they bring your steak on a heated stone to the table, which allows you to finish cooking your meal to your personal taste. worked great on the steak and the vegetables. service was excellent, keep our drinks full and constantly checked on us."
Dined on 11/1/2013
From delicious food, to a unique
cooking concept, to the chic ambiance, to the accommodating staff, our first visit to RokPrime was a wonderful way to celebrate our 7th anniversary. We started with a bottle of yummy Wild Horse Pinot, followed by the incredible Tenderloin Bruschetta for an appetizer. For the main course, I had the 6 oz. filet, and my husband got the flat iron steak. We had our steaks brought out to us to complete the cooking on the "roks," which added a sense of fun. The steak just melted in your mouth. We also ordered the roasted corn for a side- so good! Finally, we got the warm butter cake with vanilla bean ice cream- tasty. George, our waiter, was the best. Even the owners made sure to say hi. It was a special night!"
Dined on 10/27/2013
The food is unique and delicious.
The lava rock presentation keeps the food piping hot. The wine list is pretty anemic, though."
Dined on 10/26/2013
I love that they bring it out on
the rock and you can finish it to exactly how you like it and the sauces included with the steak were delicious"
Dined on 10/25/2013
Friday night I was looking for a
spot we had not been before so I made a reservation... At first glance, ambiance was terrific, very cuddly booth in a corner that was pretty private... Good start. We ordered the Lobster stack appetizer , a bowl of the pumpkin soup, which sounded really good and the halibut to share.... And an iced tea for me and an Arnold Palmer for her... Then it all fell apart :-( Appetizer was great ! Soup we never did get... Halibut was very dry almost inedible. Potatoes cold and my side of asparagus was just asparagus, big ones - not very good at all... Our server Cienna was very nice, but not very attentive at all...she never even checked back on us till meal was over..."
Dined on 10/19/2013
Overall fabulous dining
experience. Fun time, great food, terrific service. Need to expand their wine list."
Dined on 10/19/2013
Our waiter, George, was the
perfect guide for our dining experience because that is what RokPrime is all about. From their award winning Lobster stack appetizer which was absolutely delicious to the 20 oz. Prime Ribeye steak that we shared brought to us tableside on it's 700 degree block of Pink Hawaiian Rock Salt(what a way to cook a steak!), we had the best time ever. We will be back very soon because we still need to try the warm buttercake dessert. A Great place for a fun and relaxing experience in a very ecclectic surrounding."
Dined on 9/30/2013
Celebrated our anniversary at
RokPrime and had a wonderful evening. The waitress recommended the hanger steak and it was excellent. The creamed spinach was also delicious - not as heavy as it is in other restaurants. Great service, nice atmosphere... a good find!"
Dined on 9/28/2013
This place "Rok-ed" (pun
intended). The food was incredible - from the Breads and Spreads starter to the wedge salad and the Italian Wedding soup! We also had the flat iron steak and the rib eye medallion, and finished with their warm butter pound cake and delicious ice cream! Love that the steaks were served on a rock to keep cooking at our table. Impeccable service. Patrick and Raquel were stellar. Without asking Patrick gave me a sample of the Franciscan Cabernet which was outstanding. He then topped off my glass as a courtesy without charging us! When I ordered my cappuccino, he proceeded to have me try their espresso martini which was also amazing. I never made mention that it was my birthday but with such special treatment,"
Dined on 9/25/2013
Beautiful restaurant, unique
setting, cool bar and the appeal of steak being prepared on a lava rock - you just can't lose. Unfortunately, we walked away with our expectations let down. Two disappointments: 1. The length in which we had to wait for our meal - much longer than necessary. 2. No acknowledgement of my boyfriend's birthday, after mentioning it on my reservation. We live in San Juan Capistrano and we want so badly for this restaurant to succeed - and truly it should! However, if we didn't live in the area after our dining experience we would not be back. That is not the case for us, as I stated earlier, we are potential fans and we will be back to try once again."
Dined on 9/18/2013
we really wanted to like rok but
it was so far below our expectations. we should have known when the waitress said they were low on menus. we were the only table in the restaurant at 6pm on a Saturday. the wine list was very weak and very over priced. the food was cooked poorly and lacked taste. our server was friendly. if i was paying 15-20 for an entree, maybe i would not have been so critical but our meal with drinks was expensive and i left totally unsatisfied. also, the service does not warrant the price. i had to ask for utencils twice after apps and salad. the paper on the table gets messy and water stained wheh you have a drink with ice. it looks sloppy. again, acceptable for a lower price point."
Dined on 9/22/2013
The service was terrible. It took
an hour and a half for the entrees to arrive. Our waitress never refreshed our drinks that stood melting while we waited for our food. The salad was served on a hot plate so the dressing became a sea and the lettuce wilted. My husband had the fish which was so salty that it was un edible. Overall very disappointing."
Dined on 9/14/2013
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Rights Management – How to Get Windows 7 to Trust a Self-Signed Server Certificate
- Jayan Kandathil, Sr. Enterprise Solutions Specialist @ Adobe
During the proof-of-concept, development, and testing phases of a LiveCycle Rights Management project, HTTP over SSL is usually configured with self-signed server certificates. For instructions on configuring your appserver with such a certificate, see this and this.
When you try to connect via SSL to the appserver hosting LiveCycle from a Windows client, this will trigger an untrusted certificate warning from Internet Explorer...
Read the complete post at Adobe LiveCycle Blog.

subset: commoncrawl


text:
Molly Lundeen and Kevin Larson announce their engagement and forthcoming marriage. Their parents are Tom and Nan Lundeen, Minot, and Norm and Sherry Larson, Coon Rapids, Minn.
She graduated from Minot State University with a bachelor's degree in elementary education. She is employed by the Grand International Inn in Minot. He is attending Minot State University, where he is pursuing a bachelor's degree in criminal justice. He works at the Ward County Jail.
The wedding will be Saturday, Sept. 4, at 2 p.m. in St. John's Catholic Church in Minot. The reception will be at 5 p.m. with the dance at 8 p.m., both in the Grand International Inn in Minot. No invitations are required for the ceremony, reception or dance.


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Remote sensing helps control an invasive giant weed that threatens ecosystems and border security.
Covering the life sciences inside and out
Remote sensing helps control an invasive giant weed that threatens ecosystems and border security.
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Information picked up while we slumber can stay with us when we awake, even if we aren't aware of it.
Chemicals that change the way DNA is packaged could improve the effects of current antipsychotics.


text:
Report: Alex Rodriguez linked to Miami clinic PED list
Alex Rodriguez has been accused anew as a steroid cheat — a charge he denied through his public relations firm.
In an explosive report Tuesday by the Miami New Times, the troubled Yankees slugger was said to have used human growth hormone and other performance enhancers despite claims that he'd been clean for the last decade.
The New Times reported on what it says are detailed records of a recently closed Miami-based anti-aging clinic.
A-Rod is the biggest name on a list of players reportedly linked to use of performance-enhancing drugs through Biogenesis of America. According to the New Times report, Rodriguez's name showed up 16 times in records it reviewed from an employee of Biogenesis of America before it closed a month ago.
The Miami News Times, which The Associated Press describes as an alternative weekly, reported that records show the firm sold PEDs such as human growth hormone, testosterone and anabolic steroids.
Prominent baseball names in the report include Nelson Cruz, Gio Gonzalez and ex-Yankees Melky Cabrera and Bartolo Colon — both suspended last season for PED use with other clubs.
Though Rodriguez through a statement denied being party to this latest steroid scandal, MLB acknowledged its active investigation into the alleged South Florida drug connections with players.
Anthony Bosch, 49, the head of the shuttered Miami clinic, was linked to Manny Ramirez during his suspension for PED use in 2009. According to the New Times report, Bosch never has been charged by local or federal officials.
On Tuesday, Sitrick and Company issued the following on Rodriguez's behalf: "The news reports about a purported relationship between Alex Rodriguez and Anthony Bosch are not true. Alex Rodriguez was not Mr. Bosch's patient, he was never treated by him and he was never advised by him. The purported documents referenced in the story — at least as they relate to Alex Rodriguez — are not legitimate."
The Yankees, who owe Rodriguez a guaranteed $114 million over the next five seasons, have taken a wait-and-see approach.
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text:
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17" Curved Shaft Trimmer CS30
model # RY28120
This gas trimmer features a low emission 2 cycle engine that is light on weight and big on power. Ryobi gas trimmers are attachment capable, so you can quickly convert this trimmer to seven other tools with attachments that are sold separately. Two string heads come standard, a $20 value, which gives you the option to choose between a bump feed or fixed line string head. This trimmer is backed by a best-in-class three year consumer warranty.
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Operator's manuals
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text:
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
- Summary
- Significance
- Introduction
- Results
- Discussion
- Exp. Proc.
- Data
- References
- Supp. Info.
- Related Info.
- Comments (0)
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of GlioblastomaMethylome Alterations "Mark" New Therapeutic Opportunities in Glioblastoma
Cancer Cell, Volume 22, Issue 4,
Pages 425-437,
Publication Date 16 October 2012
Copyright © 2012 Elsevier Inc. All rights reserved.
DOI: 10.1016/j.ccr.2012.08.024
Dominik Sturm
Hendrik Witt
Volker Hovestadt
Dong-Anh Khuong-Quang
David T.W. Jones
Carolin Konermann
Elke Pfaff
Martje Tönjes
Martin Sill
Sebastian Bender
Marcel Kool
Marc Zapatka
Natalia Becker
Manuela Zucknick
Thomas Hielscher
Xiao-Yang Liu
Adam M. Fontebasso
Marina Ryzhova
Steffen Albrecht
Karine Jacob
Marietta Wolter
Martin Ebinger
Martin U. Schuhmann
Timothy van Meter
Michael C. Frühwald
Holger Hauch
Arnulf Pekrun
Bernhard Radlwimmer
Tim Niehues
Gregor von Komorowski
Matthias Dürken
Andreas E. Kulozik
Jenny Madden
Andrew Donson
Nicholas K. Foreman
Rachid Drissi
Maryam Fouladi
Wolfram Scheurlen
Andreas von Deimling
Camelia Monoranu
Wolfgang Roggendorf
Christel Herold-Mende
Andreas Unterberg
Christof M. Kramm
Jörg Felsberg
Christian Hartmann
Benedikt Wiestler
Wolfgang Wick
Till Milde
Olaf Witt
Anders M. Lindroth
Jeremy Schwartzentruber
Damien Faury
Adam Fleming
Magdalena Zakrzewska
Pawel P. Liberski
Krzysztof Zakrzewski
Peter Hauser
Miklos Garami
Almos Klekner
Laszlo Bognar
Sorana Morrissy
Florence Cavalli
Michael D. Taylor
Peter van Sluis
Jan Koster
Rogier Versteeg
Richard Volckmann
Tom Mikkelsen
Kenneth Aldape
Guido Reifenberger
V. Peter Collins
Jacek Majewski
Andrey Korshunov
Peter Lichter
Christoph Plass
Nada Jabado
Stefan M. Pfister
Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany
Division of Molecular Genetics, German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany
Division of Epigenetics and Cancer Risk Factors, German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany
Division of Biostatistics, German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany
Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany
Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany
Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, 69120 Heidelberg, Germany
Department of Neurosurgery, Heidelberg University Hospital, 69120 Heidelberg, Germany
Department of Neuropathology, Heidelberg University Hospital, 69120 Heidelberg, Germany
Department of Neurooncology, Heidelberg University Hospital, 69120 Heidelberg, Germany
Departments of Pediatrics and Human Genetics, McGill University, McGill University Health Center Research Institute, Montreal, QC H3Z 2Z3, Canada
Division of Experimental Medicine, Montreal Children's Hospital, McGill University Health Center Research Institute, Montreal, QC H3Z 2Z3, Canada
NN Burdenko Neurosurgical Institute, Moscow, 125047, Russia
Department of Pathology, Montreal Children's Hospital, McGill University Health Center Research Institute, Montreal, QC H3H 1P3, Canada
Department of Neuropathology, Heinrich-Heine-University, 40225 Düsseldorf, Germany
Department of Hematology and Oncology, Children's University Hospital Tübingen, 72076 Tübingen, Germany
Department of Neurosurgery, University Hospital Tübingen, 76076 Tübingen, Germany
Virginia Commonwealth University, Richmond, VA 23298, USA
Pediatric Hospital, Klinikum Augsburg, 86156 Augsburg, Germany
Pediatric Hospital, Klinikum Heilbronn, 74078 Heilbronn, Germany
Prof.-Hess-Kinderklinik, Klinikum Bremen-Mitte, 28177 Bremen, Germany
Children's Hospital, Helios Clinics, 47805 Krefeld, Germany
Children's University Hospital, 68135 Mannheim, Germany
Department of Pediatrics, University of Colorado Denver, Aurora, CO 80045, USA
Division of Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA
Cnopf'sche Kinderklinik, Nürnberg Children's Hospital, 90419 Nürnberg, Germany
Department of Neuropathology, Institute of Pathology, University Würzburg, 97080 Würzburg, Germany
University Children's Hospital, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany
Institute of Pathology, Department of Neuropathology, Hannover Medical School, 30175 Hannover, Germany
McGill University and Genome Quebec Innovation Centre, Montreal, QC H3A 1A4, Canada
Department of Molecular Pathology and Neuropathology, Medical University of Lodz 92-216 Poland
Department of Neurosurgery, Polish Mother's Memorial Hospital Research Institute, Lodz 93-338 Poland
2nd Department of Paediatrics, Semmelweis University, Budapest H-1094 Hungary
Department of Neurosurgery, Medical and Health Science Center, University of Debrecen, H-4032 Debrecen, Hungary
Program in Developmental and Stem Cell Biology, Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, University of Toronto, Toronto, ON M4N 1X8, Canada
Department of Oncogenomics, AMC, University of Amsterdam, Amsterdam 1105 AZ, The Netherlands
Departments of Neurology and Neurosurgery, Henry Ford Hospital, Detroit, MI 48202, USA
Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom
Department of Human Genetics, McGill University, Montreal, QC H3Z 2Z3, Canada
Corresponding author
These authors contributed equally to this work
These authors contributed equally to this work
► We identified six distinct GBM subgroups based on global DNA methylation patterns ► Three epigenetic GBM subgroups correlate strictly with mutations in H3F3A and IDH1 ► H3F3A K27- and G34 mutant GBMs clearly arise in different anatomic compartments ► One GBM subgroup (G34) lacks important markers of neural lineage commitment
Glioblastoma (GBM) is a brain tumor that carries a dismal prognosis and displays considerable heterogeneity. We have recently identified recurrent H3F3A mutations affecting two critical amino acids (K27 and G34) of histone H3.3 in one-third of pediatric GBM. Here, we show that each H3F3A mutation defines an epigenetic subgroup of GBM with a distinct global methylation pattern, and that they are mutually exclusive with IDH1 mutations, which characterize a third mutation-defined subgroup. Three further epigenetic subgroups were enriched for hallmark genetic events of adult GBM and/or established transcriptomic signatures. We also demonstrate that the two H3F3A mutations give rise to GBMs in separate anatomic compartments, with differential regulation of transcription factors OLIG1, OLIG2, and FOXG1, possibly reflecting different cellular origins.


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1 hr ago | The Escapist
Poisoned Puppy Saved By Extreme Drunkenness
Veterinarians in Australia quickly determined that the only way to save Charlie from poisoning was to get him out-of-his-mind drunk.
Trending on the Topix Network
Agent provocateur has designs on us
French fashion designer Jean Paul Gaultier has been the agent provocateur of the fashion world since his very first shows in the late 1970s and early 1980s.
Young at risk as flu strikes early
HE SWEARS uncontrollably, smashes his fist into walls and once broke a relative's wrist.
Drones Used To Smuggle Drugs Into Prison
Daniel_Stuckey writes "Over the weekend, Ma 28-year-old man was arrested on suspicion of using a small quadcopter drone to smuggle an unknown quantity of illegal drugs into a prison in Melbourne, Australia.
Dannii Minogue Runs A Worm Farm At Home
The star returned to her native Melbourne, Australia last year but she still travels to the U.K. frequently because of work commitments and to stay in touch with her elder sister Kylie, who lives in London.
Meet the lady bosses of Alpine
INDIE pop band Alpine are unusual for being fronted by two women vocalists. And making music together has only strengthened the friendship of Lou James and Phoebe Baker.
Vodka Saves Puppy Sick On Anti-Freeze; Australian Maltese Terrier Had ...
A Melbourne animal clinic saved a Maltese terrier's life this weekend by feeding him vodka after he had consumed anti-freeze.
Matthew McConaughey, God and humility
David is a technology entrepreneur, community activist, writer and public speaker.
As one of the longest-running and best-attended water ski events in the history of the sport, the Moomba Masters held on the Yarra River in Melbourne, Australia, continues to be the ultimate proving ground for pros around the world.
Deciphering Putin's plan in Ukraine
The Age Canberra Times Sydney Morning Herald March 8, 2014 Saturday Deciphering Putin's plan in Ukraine Vladimir Putin 'It remains to be seen whether Putin wants to crush Ukraine, or merely cripple it as a regional player, which, he would hope, would leave it at his mercy economically' Paul McGeough, Chief Correspondent, Washington Never has one ... (more)
Man uses toy helicopter drone in attempt to smuggle drugs and...
Fifty thousand Orthodox Jews take over TEN BLOCKS of New York in protest over Israeli army plan to draft devoutly religious men 'I wish he had never been born': Adam Lanza's father breaks his silence on 'evil' son who killed 20 children at Sandy Hook school in first interview since tragedy Mexican cartel leader dubbed 'The Craziest One' dies in ... (more)
Man Accused Of Using Drone To Smuggle Drugs Into Prison
While Amazon's drone delivery service plans might not be feasible for regular deliveries, there may well prove to be a niche for the short-distance transportation of high-value goods - case-in-point a recently foiled plot to smuggle drugs and a cell phone into a maximum security Australian prison.
Bottle of vodka provides miracle cure for dying dog
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Cardboard Carton Lights - The Groovie Lamp is Lightweight, Portable and Recyclable
In terms of a second life for an old light fixture, the best you can typically hope for is to hand it down to somebody else or to turn it into an eccentric craft.
Ten Tenors bring touch of Broadway to Pavilion
The all-male Australian troupe Ten Tenors will stop in Sioux Falls on Friday to perform their "Ten Tenors on Broadway" show.
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Gangs in Disneyland? Yes, but it's not what you think
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Strange Talk on Tour with the Sounds; Album Out 4/29
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-Full-service hotel with spa, exercise facility, ski storage, restaurants and a bar -AAA Four-Diamond hotel -Alongside the beautiful Lakeside Village -Private ski shuttle to the slopes -Valet parking -Free ski check at base of River Run -Fast Pass to skip lift lines at the gondola prior to 10am
The AAA Four Diamond Award-winning Keystone Lodge & Spa is surrounded by the majestic Rocky Mountains and thousands of acres of national forest, making it the ideal choice for winter sports enthusiasts. The Keystone Lodge boasts easy access to a host of winter and summer activities, including the skiing and snowboarding, ice skating, mountain biking, championship golf, Stand-Up Paddle Boarding and more. Take a break from your adventures and relax in our state-of-the-art spa with a full range of rejuvenating spa treatments. The lodge also includes a steam room, indoor and outdoor hot tubs, and an outdoor heated swimming pool. Treat yourself to an exceptional dining experience at the Bighorn restaurant while taking in the splendid views of the Continental Divide and Keystone Lake. Or grab a quick bite at the convenient Lakeside Deli or Edgewater café before heading off on your day's adventures. Getting to the slopes is easy with the Lodge's Gondola Express shuttle service. Our private van will whisk you from the front of the Lodge to the base of the gondola. Plus, as a Lodge guest you receive free ski check at the base of the gondola and a complimentary Fast Pass which allows you to use the ski school line prior to 10am. How convenient is that? The lodge offers 152 guest rooms, including 14 loft suites. Each room affords a spectacular view of the Mountains and the Snake River. The hotel suite is a two-level room with one king bedroom upstairs in the loft with television. All suites also include a downstairs sitting area with television and sofa pull-out couch and one private bathroom downstairs. All rooms include complimentary in-room Wi-Fi, complimentary fitness center access, plush robes, and many other amenities. The Lodge also has a business center and over over 10,000 square feet of meeting space.
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Recognized as a Center of Excellence by the American Society for Bariatric & Metabolic Surgery
Published: May 29, 2007
Updated: June 30, 2010
To familiarize you with available procedures, Duke Aesthetic Services offers a full array of seminars, personal consultations, and literature.
Free seminars are conducted by Duke physicians and provide you with an opportunity to learn about various procedures in more depth. A list of offered procedures is displayed on their Web site.
Plastic surgery following weight-loss surgery is considered an elective procedure. It usually is not covered by insurance companies unless there are strong medical indications.


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Adjustable Strap FinsAn adjustable strap diving fin is more versatile - because they have an open heel, they can be paired more easily with dive socks or dive boots, allowing a diver to operate in colder water. The adjustable straps themselves can be changed out and customized to allow for any kind of gear to be worn beneath the fin. This flexibility is what makes the adjustable strap fins the preferred fin of scuba divers everywhere. Adjustable strap fins usually have a larger surface area than full foot fins, as well, which is ideal for propelling a scuba diver strapped down with bulky gear. |
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This class is a bummer! We needed 8-10 juco's.
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This class is a bummer! We needed 8-10 juco's.
"Guarantee"? So, how are you guaranteeing it if you are wrong? I always like the "money back" variety myself...:wink:
I think that both of these guys classify as "mystery meat" recruits. English, you can't even be sure the staff hasn't pulled his offer.
Maggitt, on the other hand, has kept his ISU recruitment about as low profile as possible, barely acknowledging that we are a "finalist", while he chatters on about every other school that he visits. It would be great to get him, though. You find a place for an athlete like that. :biggrin:
I would think that this rule only applies to a specific year. Schools can probably get around it by counting back some mid-year signings to the previous year and offering gray-shirting some guys to the next year class. Most SEC schools won't let a silly little rule stop them from finding a creative way to get what they want.
What do you mean?? I personally think this class is rounding out to be pretty great, you can judge everything on the star system but if you do we really only have 2 kids that are not at that 3star or borderline 3 stars area(5.4 rival rating) I like that we are in the running for a lot of kids, this is probably the most exciting recruiting cycle since Sed (aggie/cyclone) flip on NSD, and we know how he panned out. I am really encouraged and excited on how hard we are hitting FL with the Burnham's. Very pumped to see what happens the next couple of weeks.....


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State law requires advance notice of such actions except in cases of emergencies that endanger public safety or the state's coffers.
The fallout from Marple's firing has been far ranging.
Tuesday night, Marple supporters rallied in Charleston to demand an explanation for her firing and to call on Gov. Earl Ray Tomblin to remove five members from the state Board of Education, including former first lady Gayle Manchin.
Some, including the West Virginia Education Association, have blamed Marple's firing on a political faction tied to Manchin and her husband, U.S. Sen. Joe Manchin.
Gayle Manchin has denied political motives.
One of the three Mountain State Justice lawyers who filed the suit is Dan Hedges. Hedges was once married to Attorney General Darrell McGraw's top aide, Fran Hughes. McGraw is married to Marple.
Hedges is the lawyer whose class-action lawsuit on behalf of Lincoln County students caused the landmark 1982 Recht Decision that ruled state schools must be equitably funded.
Wednesday's suit was filed on behalf of James and Michelle Hicks, the parents of a fourth-grader with special needs in Boone County.
Staff writer David Boucher contributed reporting to this article.
Contact writer Ry Rivard at ry.riv...@dailymail.com or 304-348-1796. Follow him at www.twitter.com/ryrivard.


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Hurricane Katrina bears down on the Gulf
coast of Louisiana and Mississippi in this satellite photo taken on
August 28, 2005. (Photo credit: NOAA)
More on
However, that makes it the lowest pressure in any Category 3 hurricane that has hit the U.S. 920 millibars was actually a lower pressure than the 922 in Category 5 Hurricane Andrew at landfall. Katrina's large size resulted in a very large portion of the U.S. coastline (from the Florida panhandle to western Louisiana) feeling the effects of its winds, waves and water rise.
No matter the category, this hurricane produced huge waves exceeding 40 feet and a coastal water rise based on best estimates that was somewhere between 26 and 31 feet in height. That makes it the greatest water rise on record in a U.S. hurricane.
The results were catastrophic for coastal western Mississippi where homes were washed away more than a quarter of a mile inland from the coastline. What made Katrina a catastrophe in New Orleans was not the hurricane itself, but rather the failure of the levee system.
Several breaks during and shortly after landfall resulted in widespread flooding of New Orleans with water as high as 10-20 feet deep in some portions of the city. People that failed to evacuate this city, parts of which are below sea level, were trapped atop their rooftops and many never made it that far, as they drowned in the floodwaters or perished in the event from heat, lack of water, severe stress or lack of medical attention while stranded.
The New Orleans Superdome became a refuge for 1,000s as the ordeal unfolded from helicopter for all of America to witness. This man-made disaster was compounded by the fact that water in the city receded very slowly (days) and some just stayed until it was pumped out.
Katrina left devastation in its wake all
along the Gulf coast like these destroyed homes in Gulfport, Miss.
(Photo credit: NOAA)
These islands acted as a partial buffer to the waves and surge from hurricanes in the past. The next one will have fewer and smaller barriers in its path. Katrina will be remembered as a huge hurricane with record water rise and will always remind us of the vulnerable coastlines the U.S. has created over the past 100 years that have become disasters waiting to happen.
Hurricane Katrina, the costliest hurricane in U.S. history, has been estimated to have cost at least $108 billion dollars. That does not count the economic losses from displaced people and lack of commerce in the areas affected well after the event took place.
The number of fatalities directly related to Katrina is estimated to be about 1,200.
The city of New Orleans lies flooded by
the waters of Lake Pontchartrain in the immediate aftermath of
Hurricane Katrina. (Photo credit: NOAA)


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Adonis Stevenson faces Tavoris Cloud in his first defense of the WBC light heavyweight title tonight on HBO.
Catch up on fights you missed the past weekend. Countries highlighted in this recap include the United States, the United Kingdom, Argentina, Thailand, Mexico, Poland, Italy, Ukraine, Hungary, Canada, Germany, Belgium, Latvia, and Puerto Rico.
Arthur Abraham rematches Robert Stieglitz in the headline bout of the weekend, with Robert Helenius, Don George, Billy Joe Saunders, Adonis Stevenson, Celestino Caballero, and more also in action.
Friday boxing results from around the world. Featured: Erislandy Lara, Carlos Molina, Antonio Escalante, Pongsaklek Wonjongkam, Jose Luis Castillo, and more.
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Cold Mountain
Jude Law Actor , Nicole Kidman Actor , Renée Zellweger Actor , Eileen Atkins Actor , Brendan Gleeson Actor , Philip Seymour Hoffman Actor
MPAA Rating:
Contains:Brief Nudity,Adult Situations,Not For Children,Sexual Situations,War Violence
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Cold Mountain
Theatrical Release Date: 2003 12 25 (USA)
Studio: Fox Home Ent. (lgf)
MPAA Rating: R Contains:[Brief Nudity, Adult Situations, Not For Children, Sexual Situations, War Violence]
Summary: Based on the novel by Charles Frazier, Anthony Minghella's star-studded Cold Mountain is a sweeping tale set in the final days of the American Civil War. Jude Law stars as Inman, a young soldier who, despite an injury, is struggling to make his way home to Cold Mountain, NC, where his beloved Ada (Nicole Kidman) awaits. In Inman's absence, Ada befriends Ruby (Renée Zellweger), who helps her keep up her late father's farm. Meanwhile, in his travels, Inman encounters a menagerie of interesting folks. Also starring Natalie Portman, Giovanni Ribisi, Donald Sutherland, and Philip Seymore Hoffman, Cold Mountain features original music by Jack White of the White Stripes. ~ Matthew Tobey, Rovi
Category: War
Awards: Best Picture - Drama – null Best Performance by an Actress in a Motion Picture - Drama – null Best Performance by an Actor in a Motion Picture - Drama – null Best Supporting Actress – null Best Director – null Best Screenplay – null Best Score – null Best Song – null Producer of the Year – Producers Guild of America Producer of the Year – Producers Guild of America Producer of the Year – Producers Guild of America Producer of the Year – Producers Guild of America Best Adapted Screenplay – Writers Guild of America Best Supporting Actress – Screen Actors Guild Best Actor – Academy of Motion Picture Arts and Sciences Best Cinematography – Academy of Motion Picture Arts and Sciences Best Editing – Academy of Motion Picture Arts and Sciences Best Score – Academy of Motion Picture Arts and Sciences Best Song – Academy of Motion Picture Arts and Sciences Best Song – Academy of Motion Picture Arts and Sciences Best Song – Academy of Motion Picture Arts and Sciences Best Adapted Screenplay – National Board of Review Best Picture – National Board of Review Best Supporting Actress – Academy of Motion Picture Arts and Sciences Best Original Score – Chicago Film Critics Association Best Cinematography – Chicago Film Critics Association Best Supporting Actress – Chicago Film Critics Association Best Cinematography – American Society of Cinematographers Best Song – Hollywood Foreign Press Association Best Screenplay – Hollywood Foreign Press Association Best Performance by an Actor in a Motion Picture - Drama – Hollywood Foreign Press Association Best Performance by an Actress in a Motion Picture - Drama – Hollywood Foreign Press Association Best Picture - Drama – Hollywood Foreign Press Association Best Score – Hollywood Foreign Press Association Best Director – Hollywood Foreign Press Association Best Performance by an Actress in a Supporting Role in a Moti – Hollywood Foreign Press Association
Audio commentary with Screenwriter/Director Anthony Minghella and Editor Walter Murch
"Climbing Cold Mountain" documentary
The words and music of Cold Mountain - Royce Hall Special
A journey to Cold Mountain
Sacred harp history
Storyboard comparisons
Cold Mountain
Format: Blu-ray
Release Date: 01/31/2012
Aspect Ratio: 2.35:1 Cinemascope
Audio: DHMA null
Runtime: 154 Minutes
Sides: 1
Number of Discs: 1
Language(s) English
Subtitles: English,Spanish
Region: Blu-ray region A (North America, Central America, South America, Japan, Taiwan, North Korea, South Korea, Hong Kong, Southeast Asia)
Dana Rowader
Anthony Minghella's Cold Mountain is at once a beautifully shot, contemplative film about the Civil War South, and a messy, uneven narrative that fails to fully engage the viewer. Chief among the film's problems is its unbalanced mix of romance, war drama, road movie, and ensemble film elements. Considering the fact that this film is, at its heart, a romance, it is unfortunate that the leads lack chemistry. Although part of this may be due to the fact that both actors are playing very internalized characters -- Kidman a shy and unsure belle, and Law a thoughtful, yet introverted, man of few words -- they just do not stir up the requisite amount of passion when onscreen together for their love story to be compelling. There is also little foundation for their relationship in the story line since they barely interact with each other before their separation. Attempts to convey Ada's (Kidman) inner thoughts through voice-over readings of her love letters fall into melodrama, and Inman's (Law) repeated gazing at Ada's daguerreotype falls short of conveying more than escapist sentiments amidst his harsh surroundings. In fact, his decision to desert the Confederate Army seems to be grounded more in his own desire to get away from the bloodshed and death than in acquiescence to her call for his return.
Thankfully, there is much more to both of their stories than their supposed love for each other. Though Ada and Inman maintain rather aloof personalities, even in their separate stories, they still have a multitude of other characters with which to interact. The film is bursting at the seams with colorful "country folk," disturbing opportunists, and sad souls -- many populated by recognizable character actors and minor stars. From the sinful Southern preacher played by the always-intriguing Philip Seymour Hoffman to the desperate, widowed young mother portrayed with ferocity by Natalie Portman, these characters are the lifeblood of the film. The larger supporting roles are taken by those in Ada's life, including a devastating turn by Kathy Baker as her neighbor and a moving turn by Donald Sutherland as Ada's wise father. Renée Zellweger's feisty performance as a down-home girl who helps Ada run her farm, becoming her closest friend in the process, may be considered by some as hamming it up or chewing the scenery; however, her character injects life into the film where it would otherwise have fallen horribly flat. The problem with all of these many performances is that they upstage the two leads. In this barrage of characters, even many cameo performers come across as full-blooded, three-dimensional personalities, while Ada and Inman seem more like blank slates.
Helping out the film immensely is its wonderful musical score by Gabriel Yared and its many traditional country and folk tunes. The work of Alison Krauss, Jack White, and many other artists really brings the film to life, giving the Southern characters and environment a sense of authenticity throughout. Yared's score imbues the romance with a subtle, understated warmth that it could not have accomplished on its own and works beautifully with the sweeping, gorgeous cinematography. One should be warned that the film is very gruesome and brutal in parts, truly depicting the savagery of war and the anarchy that overran the South as the Civil War was being lost. This brutality, characterized at first on the actual battlefield, but also in many of the characters' heartless actions, threatens to overwhelm the love story and any hope the film seeks to offer. The movie seems to want its romance to be the unifying element, but the love story ends up feeling more like an ineffectual backdrop most of the time, not strong enough to balance out the disheartening elements of the film. Cold Mountain is really a beautifully crafted movie; it's just a shame that many of its disparate elements could not come together to create a cohesive cinematic experience. ~ Dana Rowader, Rovi
Cast and Crew:
Jen Apgar
Emily Deschanel
Robin Mullins
Mark Jeffrey Miller
Jay Tavare
William Horberg
Anthony Minghella
Anthony Minghella
Sydney Pollack
Iain Smith
Executive Producer
Bob Weinstein
Executive Producer
Harvey Weinstein
Executive Producer
Gabriel Yared
Composer (Music Score)
Ron Yerxa
Albert Berger
Bob Osher
Executive Producer
Jude Law
Nicole Kidman
Renée Zellweger
Eileen Atkins
Brendan Gleeson
Philip Seymour Hoffman
Natalie Portman
Giovanni Ribisi
Donald Sutherland
Ray Winstone
Kathy Baker
James Gammon
Charlie Hunnam
Jack White
Ethan Suplee
Jena Malone
Melora Walters
Lucas Black
Taryn Manning
Tom Aldredge
James Rebhorn
Country: USA


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Papiss Cisse had two goals chalked off as Newcastle drew 0-0 with Metalist Kharkiv in the Europa League at St James' Park. More
Manager: Alan Pardew
Manager: Miron Markevich
Yvonne , youre not wrong there pet, anything else?
david: grow up and give the computer back to your nursery teacher
put out a strong team in first leg so you can put your feet up in the 2nd leg another tactical error by mr pardew when will he be at last for what he his a born loser look at all his other clubs he is out of his depth
deluded mags believe pardes hype and bullsh//t they even saying who they are playing in the next round this team are on a break in the season they even struggled against whitley bay
JOSEPH, how did the Mackems come on tonight, oh! I remember, they came nowhere near qualifiying for this competition,they were too busy trying to save their #$%$ from the championship just like again this season.
joe t, they werent playing Chelsea !!
Linesmans are #$%$ and poor cisse it's not his fault he nearly got a hat trick
Oh Joseph,so Chelsea are not a decent team then!
We were robbed for two goals, i watched the match and you can see that they were BOTH onside!
Is dioma lionsa!
Looks like the Toon are 4-ked,what did I tell ya, soon as they meet a decent team, well you can concentrate on the relegation dog fight now girls !
can we play whitly bay next week?
Edith you quite right we all must support one another so come on you mags and mackems!!!!!!
are these officials bent?
I am one of those ''sad little mackems'' that Matthew was ranting abt. unlike some, I like ALL our local teams to do well, apart from when they play us. I cannot stand bigots of any sort. we have enough probs in this area, without turning on each other.
I don't support Newcastle, my team wear red/white! most of my friends are mags though & even I know it is back to it's proper, proud name, despite Ashley & co.
Taylor trying to rape the ball boy
Get Tiote off before he reduces us to 10 men.
The toon can do this with some Sissoko Magic
Sorry! Obertan is having a cracker of a game IMO


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Looking to put a little more romance in your life? It's never too late to go out on a date, even if it's with your own spouse. Whether you're in a relationship or wish you were, here are some resources to keep you informed on the issues of senior dating, senior sex, and romance after 50.
- Cohabitation (3)
- Dating Again (5)
- Healthy Senior Sex (10)
- Online Dating (5)
- Romance (2)
Dating and Romance - How My Greatest Romance Began
Every relationship has a story, and we want to hear yours. Whether you met the woman or man of your dreams online, at a church social or in a biker bar, whether your great romance is with the person sitting beside you or the one who got away, we want to hear how it all got started. When and where did you meet? How did you first know you had...


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Red wines that are more fruit-forward and lighter in tannin and body.
Medium bodied reds that go down easy, with smooth tannins and supple fruit.
Wines where earthy and/or spicy dominate the flavors – typically medium to full body.
Full bodied wines that have concentrated fruit and are higher in alcohol and/or tannins. Some need age.
This sophisticated Felino Malbec carries a deep magenta hue and aromas of dark berries and anise. On the palate, intense, pure flavors of just-picked raspberries, black plum and graphite unfold in velvety layers. Exotic notes of ginger and white pepper carry through the mid-palate to intermingle with firm tannins and notes of cedar on the finish.
"Spice and game notes mark this dark yet racy red, which features a core of spicy blackberry, kirsch and raspberry notes on the broad finish." 89 Points Wine Spectator
The wines of Vina Cobos are the result of a shared dream inspired by the passion of three winemakers: Paul Hobbs and Argentine parters Andrea Marchiori and Luis Barraud. Their founding aspiration: to produce a Malbec of power and elegance unequalled anywhere in the world. THe inaugural 1999 vintage of Cobos Malbec received the highest score upon release for any Argentine wine and...Read More About Vina Cobos
(ahr-jen-TEE-nah) Now fifth in the world for wine production, Argentina is catching up in the quality wine sector. A long time wine producer, Argentina used to make wine in order to drink it, not export it. And so the wines produced were quaffable and rustic and made for the local's everyday dinner. Yet it's hard not to get caught up in the wine market of the world and some...Read More About Argentina
Malbec(MAHL-beck) Angel of Argentina Originally a common grape in Bordeaux, Malbec adds only a small percentage to the blends there. It has, however, found another region in which to flourish -the bourgeoning wine region of Argentina. In fact, Argentinians have adopted Malbec as their national grape! Notable Facts Malbec is used in small amounts in...Read More About Malbec
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Cramer's 6 Stocks in 60 Seconds: ADP CSCO NRG QCOM UNH BMRN (Update1)
Check out Jim Cramer's latest trading recommendations on "Action Alerts Plus".
Updated from 10:15 a.m. ET to include closing information.
NEW YORK (TheStreet) -- Here's what Jim Cramer had to say on CNBC's "Squawk On The Street" Monday:
Strong numbers from payroll processor Automatic Data Processing (ADP) is good news for employment in America, Cramer said. He is also bullish on Qualcomm (QCOM), a company that benefits as 4G smart devices continue to proliferate faster than expected.
ADP closed off 1.7% while Qualcomm finished the day up nearly 2%.
Shares of Cisco (CSCO) will continue to suffer as telco spending remains sluggish. He was also bearish on NRG Energy (NRG) because the company has a focus on electric cars. Cisco shares were virtually unchanged at the close Monday while NRG were off nearly 1%. In the health-care space, Cramer said UnitedHealth Group (UNH) continues to do well, even under the Obama administration, as does orphan drug maker BioMarin (BMRN), which received positive news of one of its drugs earlier Monday. UNH closed nearly 1% lower while those of BioMarin jumped a healthy 31%. --Written by Scott Rutt in Washington, D.C. To email Scott about this article, click here: Scott Rutt Follow Scott on Twitter @ScottRutt or get updates on Facebook, ScottRuttDCSelect the service that is right for you!
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Combined Heat and Power Partnership
California Clean Energy Committee
Contact Name | Eugene Wilson |
email@example.com | |
Address |
3502 Tanager Ave Davis, CA 95616 |
Phone | (530) 756-6141 |
Partner Services | Non-Governmental Organization (NGO) |
Partner Profile
California Clean Energy Committee is a tax-exempt, non-profit organization that advocates for energy efficiency and renewable energy, including CHP, throughout California. The organization is interested in advancing opportunities and public education for CHP at combined cycle gas turbine plants. |


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When: | Thu, Jan 24, 2013 2:30 PM - 4:45 PM - Add to Calendar |
BIG FRIENDS/LITTLE FRIENDS - After School Program at Valley View Housing Development Children needs mentors to help with their homework and in planning fun activities. You can sign up to go on Monday or Thursday, 2:30 until 4:50 p.m. Transportation is provided. Help a child be the best they can be. Sign up in Campus Ministry. For more information, contact Victoria Pezdirtz at email@example.com
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2011 got off to an exciting start with the announcement of Kepler-10b, the first rocky planet ever discovered outside our solar system. The announcement was widely expected. Last August, a NASA scientist referred to 140 candidates for rocky planet status and now, it appears, they have a confirmed result. The discovery was announced at the a meeting of the American Astronomical Society by Nasa's Kepler team, accompanied by a press release. Richard Kerr, writing in Science, pointed to the significance of the find:
"Astronomers have announced the discovery of an extrasolar planet not much larger than Earth - the smallest exoplanet yet found. Although the world orbits too close to its sun to sustain life, the finding is a milestone in the quest to find out how common Earth-sized, habitable planets really are. It also shows that, with some luck and some innovative new technology, astronomers could be announcing the discovery of a habitable Earth-like exoplanet within a few years."
Artist concept of Kepler-10b (Credit NASA, source here)
According to NASA, the planet has a diameter 1.4 times that of Earth, a mass 4.6 times that of Earth, and an average density of 8.8 grams per cubic centimetre. In the words of Dimitar Sasselov, one of the scientists leading the project, "This planet is unequivocally rocky, with a surface you could stand on". However, according to Nasa, Kepler-10b orbits once every 0.84 days, and is more than 20 times closer to its star than Mercury is to our sun. The daytime surface temperature is about 1500 degrees C, making it likely that if anyone tried to stand on the irradiated surface, there would be a danger of sinking into molten lava. Furthermore, at these temperatures, there is no prospect of the planet retaining an atmosphere.
What then is the significance of this discovery? Several reasons have been adduced. First, it is a rocky planet. All the previous planets discovered (about 500 of them) are giant - Jupiter-like bodies. Astronomers have always expected rocky planets to be discovered when the instruments became sufficiently sensitive - but this only became possible with the Kepler instrument. Second, it demonstrates that Kepler can sense planets of comparable magnitude to the Earth. This gives encouragement that other finds will be forthcoming. "All of our very best capabilities have converged on this one result and they all converge to form a picture of this planet," said Natalie Batalha, an astrophysicist who helped lead the Kepler mission.
The other reasons offered go beyond the science and reveal the aspirations of researchers and the significance of this find for them. For these, we must look at the reports carried by the popular media. BBC News carried some informative comments:
"[. . .] as Professor Batalha explained, it is a significant step in Kepler's mission. "We want to know if we're alone in the galaxy, simply put - and this is one link in the chain toward getting to that objective. First we need to know if planets that could potentially harbour life are common, and we don't know if that's true - that's what Kepler is aiming to do."
A pioneer of the hunt for exoplanets, Geoffrey Marcy, from the University of California Berkeley, said that Kepler 10b represented "a planetary missing link, a bridge between the gas giant planets we've been finding and the Earth itself, a transition... between what we've been finding and what we're hoping to find". "This report... will be marked as among the most profound scientific discoveries in human history," he said.
These comments show that a major driver for these scientists is the quest to find planets in the habitable zone that could potentially harbour life. They are excited because here is the first rocky planet. It does not matter to them that it is not in the habitable zone, that its day side is a furnace, nor that it has lost all atmosphere and water. Finding this hostile rocky planet is nevertheless a milestone for these researchers that they are determined to celebrate. It is perhaps significant that in September 2010 another object was claimed as the first rocky planet: Gliese 581g. This was said to lie in the habitable zone of its star and have a 37-day orbit. Its mass was said to be between 3.1 and 4.3 times that of Earth. One astronomer commented: "That's the most exciting exoplanet I've seen yet". Significantly, Prof Steven Vogt, who led the team that discovered this planet, said that he was 100% convinced it would contain life:
"Personally, given the ubiquity and propensity of life to flourish wherever it can, I would say, my own personal feeling is that the chances of life on this planet are 100 percent," he said during a press briefing. "I have almost no doubt about it." [. . .] Prof Vogt estimates that as many as one in five to 10 stars in the universe have planets that are Earth-sized and in the habitable zone. With an estimated 200 billion stars in the galaxy, that means that around 40 billion planets could have the potential for life, he said.
However, excitement about this find was short-lived, as another research team reported their failure to find the signal diagnostic of Gliese 581g. This provides the context for Nasa reporting the "first solid evidence of a rocky planet". They did not have a habitable zone planet, but they are convinced that will come in the not too distant future. However, the evidence on which this hope is based is actually rather tenuous. All the extrasolar planets discovered before this first rocky Earth-like planet are either gas giants, hot-super-Earths in short period orbits, or ice giants. The presumption that there are millions of Earth-like planets in habitable zones is based on theory that is not supported by evidence. This point has recently been made by Howard Smith, a senior astrophysicist at Harvard. He has made the claim that "we are alone in the universe" after an analysis of the 500 planets discovered so far showed all were hostile to life.
"Dr Smith said the extreme conditions found so far on planets discovered outside out Solar System are likely to be the norm, and that the hospitable conditions on Earth could be unique.
"We have found that most other planets and solar systems are wildly different from our own. They are very hostile to life as we know it," he said."
This argument for extrasolar planets is essentially the same as it is for planets in our solar system. The Earth is unique in the mix of characteristics it has: size, distance from the sun, oxygenated atmosphere, substantial coverage by oceans, and so on. Based on evidence, some argue that the Earth is a Privileged Planet. The basic approach of that book is being vindicated as research discovers just how extraordinary the Earth is.
"Gonzalez and Richards counter the prevailing notion among scientists that Earth is merely an average rocky planet revolving around an ordinary star on the outskirts of an undistinguished galaxy. The authors present evidence that suggests life in the cosmos is a rarity due to a variety of prerequisite conditions, such as the unique properties of water, the peculiarities of the Earth-moon system, the sheltering effects of Jupiter and Saturn, and the fine-tuned nature of the universe. The authors maintain that these same conditions allow mankind's significant discovery of the structure of physical laws and the universe. The appendices examine a revised Drake Equation and tackle the idea of "panspermia" - the seeding of life on Earth." (Source here)
Kepler's First Rocky Planet: Kepler-10b
Natalie M. Batalha et al.
Astrophysical Journal, 2011, 729(1), 27 | doi: 10.1088/0004-637X/729/1/27
NASA's Kepler Mission uses transit photometry to determine the frequency of Earth-size planets in or near the habitable zone of Sun-like stars. The mission reached a milestone towards meeting that goal: the discovery of its first rocky planet, Kepler-10b. Two distinct sets of transit events were detected: 1) a 152 +/- 4 ppm dimming lasting 1.811 +/- 0.024 hours [. . .] and 2) a 376+/-9 ppm dimming lasting 6.86+/-0.07 hours [. . .] Statistical tests on the photometric and pixel flux time series established the viability of the planet candidates triggering ground-based follow-up observations. Forty precision Doppler measurements were used to confirm that the short-period transit event is due to a planetary companion. The parent star is bright enough for asteroseismic analysis. Photometry was collected at 1-minute cadence for > 4 months from which we detected 19 distinct pulsation frequencies. Modeling the frequencies resulted in precise knowledge of the fundamental stellar properties. Kepler-10 is a relatively old (11.9+/-4.5 Gyr) but otherwise Sun-like Main Sequence star [. . .] Physical models simultaneously fit to the transit light curves and the precision Doppler measurements yielded tight constraints on the properties of Kepler-10b that speak to its rocky composition: [. . .] Kepler-10b is the smallest transiting exoplanet discovered to date.
See also:
Kerr, R.A. First Earth-Sized Exoplanet Discovered, ScienceNow, 10 January 2011
Mann, A. Space scope finds scorched super-Earth, Nature, 469, 143-144 (10 January 2011) | doi:10.1038/469143a
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Evolution has become a favorite topic of the news media recently, but for some reason, they never seem to get the story straight. The staff at Discovery Institute's Center for Science and Culture started this Blog to set the record straight and make sure you knew "the rest of the story".
A blogger from New England offers his intelligent reasoning.
We are a group of individuals, coming from diverse backgrounds and not speaking for any organization, who have found common ground around teleological concepts, including intelligent design. We think these concepts have real potential to generate insights about our reality that are being drowned out by political advocacy from both sides. We hope this blog will provide a small voice that helps rectify this situation.
Website dedicated to comparing scenes from the "Inherit the Wind" movie with factual information from actual Scopes Trial. View 37 clips from the movie and decide for yourself if this movie is more fact or fiction.
Don Cicchetti blogs on: Culture, Music, Faith, Intelligent Design, Guitar, Audio
Australian biologist Stephen E. Jones maintains one of the best origins "quote" databases around. He is meticulous about accuracy and working from original sources.
Most guys going through midlife crisis buy a convertible. Austrialian Stephen E. Jones went back to college to get a biology degree and is now a proponent of ID and common ancestry.
Complete zipped downloadable pdf copy of David Stove's devastating, and yet hard-to-find, critique of neo-Darwinism entitled "Darwinian Fairytales"
Intelligent Design The Future is a multiple contributor weblog whose participants include the nation's leading design scientists and theorists: biochemist Michael Behe, mathematician William Dembski, astronomer Guillermo Gonzalez, philosophers of science Stephen Meyer, and Jay Richards, philosopher of biology Paul Nelson, molecular biologist Jonathan Wells, and science writer Jonathan Witt. Posts will focus primarily on the intellectual issues at stake in the debate over intelligent design, rather than its implications for education or public policy.
A Philosopher's Journey: Political and cultural reflections of John Mark N. Reynolds. Dr. Reynolds is Director of the Torrey Honors Institute at
Biola University.


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Halloween Costumes
Adult Costumes / Shop by Theme / Cop and Convict Costumes / Skull Prisoner Boys Costume
Skull Prisoner Boys Costume
Item# 01121862
Serve your time for all eternity in this Skull Prisoner boys costume. The black and white striped prisoner shirt with a 3-D skeletal chest comes complete with a pair of matching pants and an EVA white skeleton mask.
- The Skull Prisoner boys costume includes:
- Shirt with 3-D Skeletal Chest
- Tie Closure
- Pants
- Mask
- Shirt with 3-D Skeletal Chest
- Handcuffs, ball & chain and footwear not included
- Materials:
- 100% Polyester
- Wash/Care Instructions:
- Hand Wash cold
- Lie flat to dry
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San Francisco Opera
From the whimsical Showboat to the haunting La Traviata to new-to-San Francisco charming production of Madame Butterfly, an astounding season awaits you!
Subscribe now to the exciting 92nd season! From new productions of Norma and La Bohème to Berlioz's thrilling The Trojans, an epic season awaits you! Single tickets go on sale June 30, 2014.
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San Francisco Opera 301 Van Ness Avenue San Francisco, CA 94102 (415) 861-4008 Map All contact info
Secure your place today for the upcoming season and save 50% off regular ticket prices! Choose the subscription option that works best with your schedule: Full and Half Series dates and pricing Choose from a variety of 8-opera Full Series or 4- and 5-opera Half Series Semester Series dates and pricing 3-opera packages that work with your fall or summer semester 2014–15 Order Form Fill out the order form and mail with proof of status; or call the Box Office directly to place your order. Proof of Student or Teacher Status is Required Providing proof of current status ensures that student and teacher subscribers qualify for the discount. For mail orders, please send proof of status with your order. For phone orders, proof of status must be received within seven days of order placement. All subscription requests are subject to availability. ID requirements: students enrolled full-time (9 credits or more) in educational institutions can present a dated current class schedule and either a student ID card or current registration card. (In the time between school years, proof of full-time enrollment in the previous or following academic year will be qualifying proof.) Limit two seats per ID. Full- or part-time instructors at accredited educational institutions, and members of the Music Teachers' Association can present a current school ID, recent pay stub or an MTA membership identification. How to Order CALL (415) 864-3330 Mon 10am–5pm, Tue–Fri 10am–6pm, Sat 10am–6pm (phones only) MAIL: Order form with proof of status San Francisco Opera Subscriptions 301 Van Ness Avenue San Francisco, CA 94102-4509 IN PERSON Opera Box Office 301 Van Ness Avenue San Francisco, CA 94102-4509 Mon 10am–5pm, Tue–Fri 10am–6pm Students who attend the Fromm Institute for Lifelong Learning save 40% off regular ticket prices with a Fromm student subscription (proof of Fromm student status is required*). To purchase a subscription, download the order form and call (415) 864-3330 or visit the Box Office in person. * Proof of status ensures that Fromm subscribers qualify for the 40% discount. Students must provide a copy of a dated current class schedule and either a student ID card or current registration card. For mail orders, please send proof of status with your order. For phone orders, proof of status must be received within seven days of order placement. Frequently Asked Questions How many subscriptions may I buy? Each student or teacher may purchase one subscription package with up to two seats per ID. May I sit with my friends? Yes! Students or teachers who send in their order forms in the same envelope and indicate with whom they would like to sit will be seated together (subject to availability). What if I cannot attend a performance? You may give away the ticket, exchange the date or return it to the Box Office as a charitable donation. To donate tickets, please call the Box Office prior to the performance. May I exchange tickets? Tickets may be exchanged for another weeknight performance of the same opera only. Any exchanges of student/teacher subscription tickets into weekend performances, even if the original performance was on a weekend, will be made only at regular subscriber prices due to the limited number of discounted seats available. For all subscribers there is a $10 per ticket fee for exchanges made on the day of the performance. The deadline for exchanges is two hours prior to the original performance. To make an exchange, call or visit the Opera Box Office 24 hours prior to the date of the original ticket. Please have your ticket(s) in hand when you call. If you have questions regarding your subscription or exchanges, please contact the Box Office at (415) 864-3330. Do the Full and Half Series ticket benefits apply to my discounted subscription series? Sorry, the Full and Half Series early exchange benefit, the Full Series drop-one-opera option, the complimentary ticket upgrade and advance parking opportunity do not apply to Student and Teacher or Fromm discounted subscription series. When will I receive my tickets? Tickets will be mailed in early August. Remember, your order is not complete until we have received a copy of your proof of status (current student ID and schedule, or union card or pay stub). Can I subscribe online? Because we need to validate your student or teacher status, Student and Teacher subscriptions are not available online. Student Rush Student Rush tickets, when offered for evening performances, go on sale online and at the Opera Box Office at 11am on the day of the performance. When offered for matinees, rush tickets are sold only in person, starting at 11am on the day of the performance. Rush tickets will be available to anyone presenting a valid student ID in his or her own name. Tickets are $27 apiece and must be purchased either in person or online (if registered in advance). Limit two tickets per ID. Subject to availability; prices subject to change. Visit sfopera.com/rush or call the Box Office at (415) 864-3330 the day prior to the performance to inquire. Teachers and MTA members do not qualify for Student Rush tickets.
301 Van Ness Avenue San Francisco, CA 94102 Phone: (415) 864-3330
Box Office Hours: Mon 10am–5pm Tue–Fri 10am–6pm Sat 10am–6pm (phones only)