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The best crime fiction offers equal parts entertainment and social commentary — stories that we remember long after the final chapter.
These are my favorites of 2012:
1. Live by Night, Dennis Lehane: A lean, tightly focused epic that looks at Prohibition and the organized crime that flourished because of it. Lehane's 10th novel goes beyond the life of crime, skirting that fine line between glorifying the illegal and showing the humanity that exists even in mobsters. With action that moves from Boston to Ybor City, Fla., to Cuba, the novel examines our history and morality in an amoral world.
2. Gone Girl, Gillian Flynn: A wife's disappearance leads to the disintegration of what seems like a perfect marriage.
3. The Drop, Michael Connelly: Twenty years of Harry Bosch still seems fresh.
4. And When She Was Good, Laura Lippman: A suburban madam comes to terms with her career choice.
5. The Cutting Season, Attica Locke. Harper: The changing face of racism and classism intersect with the past and present on a Louisiana antebellum mansion that's managed as a tourist stop by an African American woman whose ancestors were slaves on the plantation. This artificial look at the past may be impinged upon by a corporation that has been buying up the surrounding land and hiring illegal laborers instead of local workers.
6. A Killing in the Hills by Julia Keller. Minotaur: An insightful look at the ennui of a community paralyzed by poverty and despair and the pride of people who refuse to succumb to the insidiousness of drugs.
7. The Lost Ones, Ace Atkins: A U.S. Ranger battles corruption that has overwhelmed his rural Mississippi hometown.
8. Available Dark, Elizabeth Hand: This stunning look at a woman forever teetering on the edge follows a burned-out asocial photographer from Helsinki to Iceland.
9. Defending Jacob, William Landay: What begins as a typical legal thriller matures into a suspense-laden insider's view of the law, ethics and familial bonds with a shocking finale as believable as it is surprising.
10. The Other Woman, Hank Phillippi Ryan: Politics, dirty campaigns, compromised candidates and several "other women" make for a timely tale. This political thriller delves into romantic suspense and journalism ethics.
11. The Demands, Mark Billingham: The 10th outing with London detective Tom Thorne starts as a conventional hostage novel, but then skillfully explores guilt, cultural differences and injustice.
12. Retribution, Val McDermid: London police detective Carol Jordan and crime profiler Tony Hill are targeted by an old nemesis.
13. Criminal, Karin Slaughter: A contemporary story about the vagaries of family as well as a historical look at women breaking into the Atlanta police force.
14. No Mark Upon Her, Deborah Crombie: A riveting look at the corrupting nature of power as London detectives Duncan Kincaid and Gemma Jones investigate the murder of a fellow cop who was an Olympic hopeful.
15. Broken Harbor, Tana French. Viking: An attack on a family in a failed subdivision dovetails into a fascinating look at Ireland's precarious financial situation.
Notable debuts
The Professionals, Owen Laukkanen: The economic downturn and a bleak job market make for a tense, suspenseful and insightful thriller about four out-of-work, newly graduated college friends who find employment as kidnappers.
The Three-Day Affair, Michael Kardos: Four friends from Princeton become kidnappers and robbers at their ninth annual reunion when one of their group goes off the deep end.
City of Saints, Andrew Hunt: Salt Lake City in 1930 proves an evocative setting to explore Utah's history, its people and how a person with a deep religious faith lives in an increasingly secular world.
Black Fridays, Michael Sears: An excellent character study and cautionary tale about a man coming to terms with his own limitations while trying to be a good father to a difficult, special-needs child.
A Land More Kind Than Home, Wiley Cash: Crime fiction melds with Southern gothic for an emotional, lyrical story about two brothers that explores the power of forgiveness, the strength of family bonds and how religion can be misused.
Oline H. Cogdill reviewed these book for The Sun Sentinel.


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Miami Hurricanes
- Year: Freshman
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As a Recruit: Sanders was recruited from Brophy College Preparatory (Phoenix, AZ) class of 2009. He committed to Miami on 2/4/2009.
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Orange-Green Spring Game Rosters
23 months agoThe Miami Hurricanes will hold their annual spring game on Saturday, April 14 at Sun Life Stadium beginning at 2 p.m. More
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Football Insider: 3/24
2 years agoThe Miami Hurricanes held their first scrimmage of the spring Saturday morning at Ted Hendricks Stadium in front of about 700 fans. More
Recruits Predict Billy Sanders
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2011 (SOPHOMORE): Participated as a member of the scout team ... Did not see any game action.
2010 (FRESHMAN): Played in six games, with one start on special teams.
2009 (FRESHMAN): Redshirt season.
HIGH SCHOOL: As a junior, caught three passes and had one touchdown and recorded 76 tackles which included nine sacks, one interception, two caused fumbles and two fumble recoveries ... As a senior, he recorded 86 tackles, seven sacks, one interception, two forced fumbles and two fumble recoveries on defense. He had 31 receptions and three touchdowns ... Class 5A All-State Second Team ... Lettered all four years in football at 5A Brophy College Preparatory in Phoenix and Lake City High School in Couer d' Alene, Idaho ... Played tight end, Defensive End and Long Snapper ... Led Brophy College Preparatory to 2 5A State Championships and deep into the playoffs the other two years ... Earned all-state and all-region honors as a junior and senior.
- Early Enrollee
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subset: commoncrawl


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It's Art!: Princess Peach As The Virgin Mary
This is Princess Peach as the Virgin Mary. I love the dichotomy of video game and religion. Granted I have no idea but dichotomy means but I used it to sound smart and because I'm probably the hardest hitting journalist in the industry. It's true, one time during an interview I called Mike Tyson a little bitch and then knocked all his teeth out. That's why he talks funny. Plastic teeth.
Behold, The Virgin Princess Peach [kotaku]
Thanks to harry, who's taking bets on whether Toadstool looked up Peach's skirt (and whether she has legs at all).
Note: This is is small version of the picture, click HERE to see the thing in all its high-res glory and then make it your desktop background. Or don't. Stick to your nasty bikini chicks, I don't care. This is 'The Creation of Mario' featuring Shigeru Miyamoto giving life to... / Continue →
This is a piece of handpainted art by Jude Buffum (prints available at his site) showing Rainbow Brite kicking Strawberry Shortcake's head off Mortal Kombat fatality style. There's another one of a Carebear (who I suspect is Tenderheart Bear) ripping Teddy Ruxpin's heart out ... / Continue →
Artist Kordian Lewandowski went and carved Princess Peach and Mario in the style of Michelangelo's 'La Pietà '. It is most impressive. I posted a couple more pictures after the jump, including a reference shot of the original artwork, and a shot of this one with Kordian besid... / Continue →


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Kim, Andrew
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Kim - Previous Article
The son of Harry Kim and Linnis Paris, in a potential future timeline. His mother was the daughter of Tom Paris and Kes, but this timeline was never fulfilled. His one-quarter Ocampan heritage resulted in the rapid growth and aging natural to that species.


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Abdul-Mohsen Linjawy, Assistant Secretary in the Islamic Chamber of Commerce, Industry and Agriculture (ICCIA), Director of Business Owners Union (BOU) and Young Entrepreneurs Association in the Organization of Islamic Cooperation (OIC) reviewed the preparations for holding the third Conference of both of BOU and Young Entrepreneurs Association to be held next November. This came during his visit Riyadh Chamber and his meeting with member of the Board of Directors and Head of Young Entrepreneurs Committee Aly Al-Athiem and the Secretary- General of the Chamber Hussein Al-Athel.
The meeting tackled the Conference objectives which seek to achieve many of aims including: signing a number of deals on deliberated investment projects in the Islamic countries, activating the website (Union Portal) for financing projects and marketing commercial commodities, in addition to educating business owners with the modern effective methods for increasing intra-trade among the 57 Muslim countries and spreading the successful experiments of attracting investments to OIC countries.


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Sunday, March 09, 2014
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The Orleans County Sheriff's Office is asking the public for help in finding a man they say nearly ran over two investigators. Police say they approached Allen Young last week in a parking lot in the town of Ridgeway. Investigators say Young was a person of interest in an ongoing narcotics investigation.
Police say Young fled the scene in his car, nearly striking the two investigators. As a result, he is facing two counts of first degree reckless endangerment.
Other charges are pending.


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Shermans Travel » Mexico » Riviera Maya
Riviera Maya
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Why Go
For the perfect combination of relaxation and culture in the form of beaches, resorts, and historic ruins.What's New in Riviera Maya
From Affordable to Luxe, A Look at Iberostar's Riviera Maya Resorts
November 04, 2013 by Karen Gardiner Dion
At an all-inclusive resort, we often resign ourselves to an acceptance that what we gain in dollars saved, we lose in memorable dining experiences. When all of ... Read More »
Hurricane Season Update: Risks (and Great Deals) in the Caribbean
September 16, 2013 by Alex Schechter
Nine months out of the year, Caribbean islands are a postcard-ready panorama of blue skies, swaying palm trees, and cocktail-sipping,hammock-lounging bliss. But ... Read More »
10 Inspired Lake Locales
July 18, 2013
Locally known as Jiuzhaigou, Jiuzhai is best known for its amazing blue and green lakes, incredible waterfalls, and unique wildlife, including the Giant Panda. Read More »
8 Ways to Save on Cruise Excursions
July 15, 2013 by Laura Motta
Walking on a glacier in Alaska. Swimming with dolphins in the Caribbean. Joining a lobster bake in Maine. Pondering Michelangelo's statue of David in Florence. ... Read More »
40 Sweet Spots for Spring Value
March 20, 2013 by ShermansTravel Editorial Staff
In life, being in the right place at the right time is often due to serendipity, but in travel, it almost always is a result of good planning. To avoid crowds ... Read More »
Hand-Picked Riviera Maya Deals
Our Experts save you money with travel deals and advice
Visit amusement parks in autumn for reduced admission prices and smaller crowds.
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West Indies v England, 1st T20, Barbados
Scorecard | Report | Video report - England err with selection | Dobell: England miss the muscle | Samuels backs 'trump card' Badree | Plays | Gallery | Croft: An efficient WI performance | Cozier: Commitment or cash | Highlights | Gayle's 43 | Samuels hits 69* | 'Conditions different from our last visit' - Broad
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ESPNcricinfo XI: Inspired by Abdur Rahman's 0-0-8-0, we look at some of cricket's more improbable bowling analyses
Stuck between commitment and cash
Tony Cozier: While top West Indies players have signed national contracts, they're also likely to be wooed by several T20 leagues
Australia close to becoming a powerhouse
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There are two fantastic events to enjoy at Bodicote Park this week!
Download all the information you require for Banbury's Mini Tournament 2014 which is being held on Sunday 23rd March. View Item »
Banbury's 'Old Nics' Veterans side is to get its first Cup outing this season and Mr President needs your support. View Item »
This fantastic personal achievement will see Doug's England career kick off at April's full international tri-nations tournament in France. View Item »
Banbury's Under 16 captain Jake Anderson is part-way through the RFU development and training programme that will include matches against France, View Item »
On Saturday, March 8th at 12.30 the Aviva Premiership's top two teams go head-to-head in the first semi-final of the season. View Item »
Many thanks if you who have already returned your RFU Grand Draw counterfoils and/or unsold tickets. View Item »
Micky Fox made his proud U20 debut for Oxfordshire today as they thumped Somerset 47-0 in Bristol. View Item »
The Cup tie between Banbury & Grove has been rescheduled to Wednesday 5th February with a 7.45pm kick off. Let's be having you! View Item »
January's issue of the popular regional monthly magazine features news and match reports from around the Club. View Item »


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World news about "Afghan army" published by euronews.
In Afghanistan, at least five Afghan troops have been killed in a NATO led airstrike in the east of the country. Several soldiers were also badly wounded in… 06/03/2014
2014 should be the year when the war in Afghanistan ends. Remember how it all began? The opening salvo, on that autumn Sunday, 7 October 2001, less than a… 20/12/2013
An Afghan government defender looks for attackers who fired a rocket-propelled grenade into a house used by British diplomats in Kabul city centre… 16/04/2012
NATO has handed over full control to Afghanistan's own security forces for the first time since the Taliban were overthrown in 2001. In a ceremony that was… 18/06/2013
Eight policemen have been killed by a roadside bomb in Afghanistan's volatile Kandahar province in the south of the country. They had just defused another… 27/01/2013
French combat troops in Afghanistan are preparing to come home on Tuesday as their mission officially ends. Some 400 soldiers are pulling out from their… 20/11/2012
The Afghan National Police – the ANP – can count on EU training until coalition troops withdraw in December 2014 – an extension of 18 months. Civilian… 15/11/2012
US troop numbers in Afghanistan today returned to their pre-2009 "surge" figures with the departure of the last of the extra 33,000 troops ordered in by… 21/09/2012
Despite the hand over of Bagram to Afghan authorities the US has said it will keep control of at least one block at the controversial jail. Speaking to… 10/09/2012
The Afghan flag was hoisted during a ceremony handing over control of US-built Bagram prison. Afghan authorities have taken over control of the jail after… 10/09/2012
The Afghan army said on Wednesday that it has sacked or arrested hundreds of soldiers over alleged links to insurgent groups. There is growing concern… 05/09/2012
A deal has been struck between the United States and Afghanistan to curb night raids on Afghan homes. NATO commanders had backed the raids as a key… 08/04/2012


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Article Information
Related Articles
- Biochemistry by design
Biochemistry by design
Trends in Biochemical Sciences, Volume 32, Issue 7, 1 July 2007, Pages 301-310
Barbara C. Forrest and Paul R. Gross
AbstractCreationists are attempting to use biochemistry to win acceptance for their doctrine in the public mind and especially in state-funded schools. Biochemist Michael Behe is a major figure in this effort. His contention that certain cellular structures and biochemical processes – bacterial flagella, the blood-clotting cascade and the vertebrate immune system – cannot be the products of evolution has generated vigorous opposition from fellow scientists, many of whom have refuted Behe's claims. Yet, despite these refutations and a decisive defeat in a US federal court case, Behe and his associates at the Discovery Institute continue to cultivate American supporters. They are also stepping up their efforts abroad and, worryingly, have achieved some success. Should biochemists (and other scientists) be concerned? We think they should be.
Abstract | Full Text | PDF (591 kb) - Creationism and Evolution: It's the American Way
Creationism and Evolution: It's the American Way
Cell, Volume 124, Issue 3, 10 February 2006, Pages 449-451
Eugenie C. Scott
SummaryThe recent ruling in the Kitzmiller v. Dover court case that intelligent design is a form of religion and cannot be taught alongside evolution in science classes in US public schools garnered worldwide attention. But why is the antievolution movement so powerful in the United States?
Summary | Full Text | PDF (75 kb) - Evolution: what's wrong with 'teaching the controversy'
Evolution: what's wrong with 'teaching the controversy'
Trends in Ecology & Evolution, Volume 18, Issue 10, 1 October 2003, Pages 499-502
Eugenie C. Scott and Glenn Branch
AbstractA new slogan in the fight against evolution education in the USA and elsewhere is 'teach the controversy'. Although there are scientific controversies about the patterns and processes of evolution that are appropriate topics for the science classroom, and there is a continuing social controversy in certain circles about the validity of evolution, it is scientifically inappropriate and pedagogically irresponsible to teach that scientists seriously debate the validity of evolution.
Abstract | Full Text | PDF (95 kb) - …more
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Current Biology, Volume 16, Issue 8, R265-R266, 18 April 2006
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- The Archbishop of Canterbury has announced his opposition to the teaching of creationism in schools. Nigel Williams reports.


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LATHROP – Former Lathrop-Manteca Fire Chief Jerry Sims has publicly apologized for comments he made about former Manteca city councilman Jack Snyder during a recent Lathrop City Council meeting.
The Health Occupation classes at Lindbergh School will be conducting a Safe Halloween at Sequoia School on Saturday, Oct. 31.
Sierra High Goes on Tour.
One of Manteca's longest running Safe Halloween carnivals will take Saturday, October 31, from 5 to 8 p.m. at St. Paul's United Methodist Church in the gym.
The Lathrop Elementary School was packed with a steady flow of families on Oct. 17 as the school decided to bring back the carnivals of the past at Lathrop, originally started by the Mother's Club back in the late 1950s. Families got to choose between games such as "Goldfish, Sack Races, Lotteria, Sweet Treat Walk, Creamed, and many more. There were, at least 20 games were available to everyone. In addition to the games, there was a silent auction and a raffle. These were to raise money for classroom supplies and other school needs. The Lathrop-Manteca Fire Department came ...
The fight between South San Joaquin Irrigation District and PG&E over control of South County retail power delivery may rest on legal research being conducted by the San Joaquin County Local Agency Formation Commission.
It's turning into a daunting task
LATHROP – The section of Towne Centre Drive from the Manthey Frontage Road to Golden Valley Parkway in Lathrop has been off limits for any vehicle parking. Signs currently in place along this block behind the Target shopping center warn motorists "No Parking" is allowed at any time.
California has reduced financial support to foster families by 10 percent due to the weak economy and the state budget deficit.
RIPON - The San Joaquin Valley "Swiss Echoes" will perform their Fall Concert and Dance Saturday, November 7, at the San Joaquin Valley Swiss Club hall at East Main Street and Manley Road.
MODESTO - The Associated Students of Modesto Junior College will present the fifth annual Halloween Carnival and Haunted House on Friday, Oct. 30, from 4 to 8 p.m.. on MJC's West Campus, located at 2201 Blue Gum Avenue in Modesto.
It is arguably the fun run with the most interesting characters racing through one of San Joaquin County's most picturesque fall settings.
A benefit for Connie McCormick is planned for Friday, Nov. 6, from 5 to 9 p.m. at Chez Shari.
The value of existing Manteca homes rebounded 35.4 percent during 2013 with the median selling price jumping $66,750.
Almost every Tuesday morning, Ron Howe volunteers his time and service to the Manteca Historical Museum.
Manteca's tennis courts are getting upgrades.
David Diskin doesn't want to offend anybody.
Two Manteca men in their early 20s survived a flash fire in their 1996 Chevy Lumina Monday afternoon as it was parked in a rural dirt driveway on Peach Avenue west of Union Road shortly before 2 p.m.
Top Chef launched chef Michael Midgley's star as a small-town cook with big-league potential.
Manteca Mayor Willie Weatherford wants the city staff to start taking steps to reduce water waste now and not later.
What are the immediate and long-term library needs of Lathrop, Manteca, and Ripon?
When Jennifer Munoz came up with the idea for trying to raise $3,000 to overhaul Santa's Downtown Manteca home, she knew it was going to be a long shot.


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Latest News
Oct. 7, 2005
Dr. Eugene Gallagher is featured speaker for annual Morningside College Wright Lecture series
Dr. Eugene V. Gallagher, Rosemary Park Professor of Religious Studies at Connecticut College, is the featured speaker for the annual Morningside College Wright Lecture series at 7 p.m. on Tuesday, Oct. 18, in Klinger-Neal Theatre, 3700 Peters Avenue. Gallagher's address, "What Motivates Religious Terrorism," is sponsored by the Morningside College Wright Lecture series and the college's Academic and Cultural Arts Series (ACAS). The event is free and open to the public.
Gallagher is a nationally recognized author, scholar, and teacher who specializes in the study of unconventional, controversial religious movements. He is the author of four books, including "Why Waco? Cults and the Battle for Religious Freedom in America" that was published by University of California Press in 1995. The book was co-written with James Tabor, a biblical scholar who tried to negotiate with David Koresh prior to the tragedy at Waco, Texas.
His book "The New Religious Movements Experience in America," published by Greenwood Press in 2004, is a wide-ranging study about unconventional American religious groups. Gallagher has 29 articles on primitive and classical religions in "The Encylopedia Dictionary of Religions" and has published over 50 book reviews. Gallagher has been at Connecticut College since 1978 and founded the college's Center for Teaching & Learning in 1996. He is currently the faculty fellow of the center and is chair of the Committee on Teaching and Learning of the American Academy of Relgion. His introductory religion class, "The Study of Religion," attracts more than 200 undergraduates each year.
The Wright Lecture series, which started in 1981, brings outstanding preachers, religious leaders, and prominent religious studies scholars to Morningside College. The lectures are funded by an endowment established by Dr. and Mrs. Ernest Wright.


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A traditional look with an exotic influence brings together this unique accent chest with a hand painted blue Summer breeze delicate floral design. Three drawer storage creates ample storage space.
The Chests 3 Drawer Accent Chest by Stein World is available in the Akron, Cleveland, Canton, Medina, Youngstown, Ohio area from Wayside Furniture.
A chest with doors, drawers and shelves can provide functionality, closed storage and a beautiful accent to any room in your home. Choose from a variety of door chests, chest with drawers, bombe chests, serpentine chests, scalloped chests, vintage chests, demilune chests, chest on chests, or carved chests to create stunning accent or finishing touch to your home. A eclectic array of traditional, cottage, country, tropical, contemporary or casual styled chests are featured. Introduce one of these finely crafted, ornately detailed and versatile chests to your home decor today!
The Chests collection is a great option if you are looking for furniture in the Akron, Cleveland, Canton, Medina, Youngstown, Ohio area.
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Home › Forums › General Discussion › Who got some Rare Tech N9ne Pics
This topic contains 30 replies, has 21 voices, and was last updated by Techn9cian4life 2 years, 3 months ago.
Whos got some Rare Tech N9ne Pics??
Old Ones, New Ones, just any wicked Tech Pics, ones that we aint seen before
Post Em if you Got Em!!
Check out my picasa web album. I got like 150 pics, some of them were buried deep within threads, google searches, etc.
Just A Little Taste of What I Got…
That 3rd Pic Is In TULSA!!! That White Dude, Is Noxious N8, Dude! They Bombay!
Gofer said:
the last one is class
The Second is so fukin Gangsta man, thats tha shit im talking bout and the last one is straight BAD!!
Thats what im lookin for
Keep em Comin!!
Ay is da 2nd one real? Da head looks pretty big… Da 3rd n 4th one r real 5th probly is 2
hahaha seriously i love it
xXGhost CXx said:
I can't confirm any of them 100% except for the first 1
JJ diaz said:
Cmon Dude, you siad thats just a little taste of what you got Bro, what else you got?? Thos pix are fukin bad Bro
I can't confirm any of them 100% except for the first 1 JJ diaz said: Ay is da 2nd one real? Da head looks pretty big… Da 3rd n 4th one r real 5th probly is 2
lol. The one of krizz is my favorite.
ya one of my sigs i made are in there
if i made it and have the only copy does that make it rare? lol
Dont matter bro, chuck em on
AVCP333 said:
These are not so much rare as they are just not used or seen as much, but any body could find em in a heart beat.
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The AastraLink Pro 160 is a powerful, cost-effective, easy to-use IP PBX geared specifically for Small Business. Please note: AastraLink Pro 160 integrates with the following Aastra SIP phones and expansion modules: 6730i, 6731i, 6753i, 6755i, 6757i, 6757i CT,vM670i, and M675i, 9143i, 9480i, 9480i CT and MBU 400. AastraLink Pro 160 - Features
Hardware Specifications Features » 1 Compact Flash Slot » Up to 6 Foreign Exchange Office (FXO) ports for connection to analogue public telephone lines (PSTN). Each FXO is equipped with on-hook Caller-ID detection and full G.168 echo cancellation » 2 Analog FXS ports; One is intended for fax and the second for lifeline » 2 100 Mbps Ethernet ports for connection to public and private networks » Standard 3.5mm mono audio output mini-jack for paging » Standard 3.5mm mono audio input mini-jack for music » 100-240 V AC (50-60Hz) auto-sensing power supply Codec's » ITU G.711 PCM Dimensions » Width: 11.84 inches (30.074 cm) » Depth: 6.945 inches (17.640 cm) » Height: 1 Rack Unit (1.1875 inches, 3 cm) » Weight: 3.4 lbs (1.54222 kg) Environmental » 32-104° F (0-40° C) » Humidity 10-85% non-condensing Regulatory Approvals » CSA 60950-1-03 / UL 60950-1, 1st Edition » FCC Part 68, Industry Canada » FCC Part 15 Class B, EN55022 Class B, EN55024 Software Specifications Features » Local SIP extensions, remote SIP users, SIPtrunking » Visual voicemail » Operator console » Auto-attendant (AA) with day/night/holiday scheduling and custom announcements » Interactive Voice Response (IVR) with directory number and name dialing » 3-way conference calls (3WC) » Busy lamp field monitoring (BLF) » Flexible call forwarding (CFB, CFNA, CFA) » Find-me, Follow-me (FMFM) » Call Park with visual call pickup » Call/Ring groups » Remote call pickup » Barred numbers » Custom speed-dial » Universal Plug-and-Play (UPnP) integration for easy setup of gateway/router » Auto discovery » Intercom/Page » Personal and corporate directories » Administrator Web interface (Web UI) Enhanced Features » Ability to generate call detail records (CDRs) for external billing applications » Ability to network multiple AastraLink Pro platforms across a LAN/WAN (identified by an IP address or domain name service (DNS)) » Provides an input connection that can trigger an event notification on the AastraLink Pro. A triggered event can be sent as an email, Extensible Mark-up Language (XML) message sent to the phone UI, or as a recorded prompt for voice notification » System configuration backup and recovery via Compact Flash (CF) card » Auto discovery and self provisioning of extensions » Auto fax detection and routing Protocols Supported » SIP call control » RTP and RTCP for VoIP media streams, with RFC 2833 DTMF detection » TFTP: Trivial File Transfer Protocol » HTTP: Hypertext Transfer Protocol » DHCP: Dynamic Host Configuration » SMTP: Simple Mail Transfer Protocol Administration and Management » Configuration and administration via web interface » Operation and configuration of phones via web and telephone interface Language Support » Web and telephony interfaces support internationalization, initially available in: English (US), Spanish (Latin American), French (Canadian)
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This publicity photo released by Showtime shows Don Cheadle (left) as Marty Kaan and Matt Damon as himself, in "House of Lies" on Showtime. Damon is practically becoming a TV comedy regular. Showtime said Damon will guest star next week on "House of Lies," playing what the channel called a "maniacal megastar" version of himself. (Showtime / Associated Press)
Read the article: Faces & Names: Matt Damon guest stars on 'House of Lies'


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From EatingWell: January/February 1991, EatingWell Serves Two
Rich and chocolaty, keep this sauce on hand for dipping fresh fruit in.
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Officers with the Department of Wildlife Resources were called in right away. The mountain lions were captured within minutes, and all three were put down.
One dog survived the attack. Sadly, the other one died.
The two dogs were less than a mile apart at the time of the attacks, and did not have the same owner. The dog that survived was running loose.
Phil Douglas with the DWR said that the most susceptible animals to attacks are ones that are tied up in yards and cannot get away.


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Join Date: Feb 2010
Posts: 1
Replacing Fasco 7062-3136 draft inducer blower on my Bryant Gas Furnace
I found this thread on this site from back in 2006: Replacement Inducer Blower My circumstances are very similar. I have Bryant 349M horizontal gas furnace with a Fasco 7062-3136 type U62B1, p/n 240101 OH92, 3450 rpm, class B, 115v, 60H, .70A inducer blower. It's almost identical to the one described in the above thread, except that his part number was 20000101. The squirrel cage fan jammed on the unit, causing the motor to overheat and trip-out. When I tried later to run the unit, it tripped out a couple of times and then starting running, causing the blades of the squirrel cage to shatter. I guess I could try and just replace the squirrel cage, but for safety's sake, I'm planning to replace the whole unit. Here's where it gets complicated for me. My web search found an MOT205401 OEM replacement part for $428 but the picture that goes with the MOT205401 looks identical to a Fasco A137, which sells for less than $200 online. The Fasco cross-reference tool on their web site says that the 7062-3136 has been replaced by the Fasco A168, which looks similar to my unit except that it appears to have more drain holes in it. The above thread and other threads I've found say that the A147 is the best replacement for the 7062-3136 so it's all very confusing to me. The gist of the comments is that the part should fit, have a drain hole at the bottom when mounted, and that it supply a comparable CFM airflow. My problem is, that I don't know whether any of the recommended parts provide this comparable airflow. I can't even figure out what the airflow of any of the units is. I don't want to spend $428 for the OEM replacement part. This is getting up to the price the HVAC repair guys want to charge me! I'm leaning toward buying the A168, which the Fasco xref tool is now listing as the replacement but I have a question: Will it be a safe replacement? I'm not worried about the warranty on the furnace, it's over 15 years old, but if the airflow doesn't match-up perfectly with the old part, would this be dangerous? Can anyone tell me where to find CFM specs for these units? Thanks for your help! It's cold in my house (in NJ). I hope it stays relatively warm until I can get this straightened out. Thalweg76 |
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BK Prabhakara earned a spot to represent Puravankara Bangalore team of Louis Philippe Cup after shooting a round of 44 stableford points.
Several top golfers of the country, including Anirban Lahiri and Gaganjeet Bhullar, would represent different city-based franchise teams in the Louis Philippe Cup team event.
Jeev Milkha Singh, seasoned Jyoti Randhawa and emerging star Anirban Lahiri will turn up for their respective teams in the third edition of the Louis Philippe Cup.
The Netherlands will hold three separate training camps before they arrive in Brazil for the World Cup, Dutch media reported on Thursday.
All set to make a New Year's resolution? Just consider few tips suggested by an expert to make a broad lifestyle change by better managing your emotional health.
Cocktails & Dreams borrows its concept from the 'speakeasy' bars of America during the Prohibition era of the 1920s, a time when a nationwide ban was implemented on the manufacture...


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USA 2 Posts
quote:Originally posted by nachomanI can't get any POI to download. (Points of Interest)IM registered with Pharo and i have the correct login information put into PC E755, i'm connected to internet. SO WHY IS THIS NOT WORKING.???Product ID SKU Description Serial Number Registered On004_NAV01_7.80 NAV01 Ostia 7.80 with US & Canada maps 8/20/2010
USA 686 Posts


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Alan Simons was enjoying a Sunday morning bicycle ride with his family in Asheville, N.C., two years ago when a man in a sport utility vehicle suddenly pulled alongside him and started berating him for riding on the highway.
Mr. Simons, his 4-year-old son strapped in behind him, slowed to a halt. The driver, Charles Diez, an Asheville firefighter, stopped as well. When Mr. Simons walked over, he found himself staring down the barrel of a gun.
"Go ahead, I'll shoot you," Mr. Diez said, according to Mr. Simons. "I'll kill you."
Mr. Simons turned to leave but heard a deafening bang. A bullet had passed through his bike helmet just above his left ear, barely missing him. ...Read the full article
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$150.00Built with higher quality parts and adding extra tonal control, the CMAT Mods Deluxe Compressor takes the classic Ross circuit to a whole new level. Utilizing closely matched transistors the CMAT Mods Deluxe Compressor has an extra low noise floor for dead quiet operation. Learn More -
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$195.00EarthQuaker Devices' The Warden is a studio grade optical compressor in a pedal. Character and controls for Tone, Attack, Release, Level, Sustain, and Ratio make The Warden the secret weapon of your signal chain. Learn More -
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Malekko Omicron Compressor
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Mario Responds to PETA
(No animals were harmed in the making of the Tanooki suit.)
(Source: dorkly.com)
PETA: People Eating Tasty Animals
A straight shot to the head is as cruelty-free as you can get.
(Source: College Humor)
Dog Food Not Tested on Animals
They just dared a bunch of drunk college kids to eat some. Most are okay now.
(Source: College Humor)


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The Onion Field
Gregory Powell, 'Onion Field' cop killer, dies in California prison
CommentGregory Powell, one of the men involved in the infamous 1963 kidnapping of two Los Angeles police officers that was dramatized in the novel The Onion Field, has died in California prison, officials say.
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Iron has occupied the fascination of humans from the time of the "Iron Age" until now. An increased understanding of the basic physiology of iron has led to the present day being known as the Golden Age of Iron. Iron has gained popularity with pumping iron (with the governor), golfing irons with Tiger Woods, and a host of other real and imaginary products associated with this Janus-faced, near-precious, occasionally toxic metal.
There is little daylight between iron and hemoglobin, and iron forms the basis for the structural and functional integrity of hemoglobin. Iron-containing hemoglobin can transport oxygen to distant sites, a fact not lost on phylogeny. Just as too much of a good thing can be bad, iron in surfeit can injure organs. It can also overload those who receive transfusional therapy and lurk in the interplay of genes among those who acquire excessive iron genetically. Methods to remove iron have been continuously refined and now may have reached a level of sophistication long sought after. A safe and effective iron chelator may be the best embodiment in modern medicine of the fabled Jason's Golden Fleece. Iron chelation will be more widely discussed in the Education Session on Thalassemia, scheduled to take place this morning at 9:30 a.m. and again tomorrow at 7:30 a.m. in Room 224 of the Orange County Convention Center.
Meanwhile, iron deficiency affects a substantial portion of the world population. Oral iron therapy is often ineffective or unusable in certain patients. Parenteral iron therapy, while around for more than five decades, has been refined to make it safer and more user-friendly. During this morning's "Parenteral Iron Therapy – Taking the Rust Off" education session, Dr. Michael Auerbach will discuss parenteral iron therapy, Dr. David Henry will speak about iron therapy in cancer patients, and Dr. Jeffrey Carson will present evidence for use of iron in heart failure. Each will discuss the established and newly discovered areas in the clinical use of these agents. This session is taking place in Room 311 of the Orange County Convention Center at 9:30 a.m. and again tomorrow at 7:30 a.m.
As with the clinical improvements in the use of iron, the basic understanding of the metabolism of iron has increased dramatically. Protection of the endothelium from iron during periods of hemolysis is a vital topic of interest. Heme-derived iron promotes an inflammatory and pro-thrombogenic phenotype that heme-oxygenase 1 (HO-1) protects against. In a scientific committee session on "Organ-Specific Iron Loading and Toxicity," today at 7:30 a.m. in Room 315 of the Orange County Convention Center, Dr. Gregory M. Vercellotti will talk about how increased expression of this enzyme may help ameliorate hemolysis-related endothelial damage. Similar toxicity is also seen in the kidneys, and Dr. Karl Nath will describe how a renal siderophore-binding protein is protective as it too induces HO-1. Lastly, the link between iron and degenerative neurological illnesses is explored by Dr. Tracey Rouault, where hepcidin plays a less than salutary role (yet again). If you miss this early morning session, don't worry; it's also taking place at 4:00 p.m. this afternoon.
Need to explore more about iron? There is a cornucopia of iron-related talks in the oral sessions on Monday, December 6, and Tuesday, December 7.
Dr. Manchanda indicated no relevant conflicts of interest.
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A tool to help hematologists participate in the CMS Physician Quality Reporting System.


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Is free and open code a form of infrastructure? How about the humans who write it?
I was looking at what my friend Stephen Lewis wrote in HakPakSak a few days ago specifically "...newspapers' roles as public trusts and cornerstones of our informational infrastructure i.e. sources of solid information and independent commentary essential to informed citizenry, democratic government, effective public policy, and well-functioning economies".. What this brought up for me is the notion that human beings are themselves infrastructural; especially when they are constuctive contributors to the structure we call civilization.
Here in the free software and open source (FOSS) worlds, we're used to making, and employing, building materials that are products of human mentation. There are dependencies here, and the primary ones are on the human beings who write code. And patch it. And rewrite it. And continue to improve it, making it more and more useful.
In responding to an earlier piece of mine, Alex Flether writes about what he calls "inter-lockin" a kind of positive lock-in among constructive yet constantly changing parts. What he's doing there is exploring the market mechanics of open source development. These mechanics are hard to understand from a pure dollars-and-cents perspective. Several years ago a high-ranking executive at IBM told me it took a number of years to discover that the company couldn't tell its Linux kernel hackers what to do; and that if anything it was the other way around. Again, dependencies.
But what does the code itself depend on? What are the first sources of open code's enormous "because effects"?
I think this is a subject we need to bear in mind as we come to debate matters as wide ranging as media ownership (newspapers, for example) and health care, over the next few years (during and beyond the next major election cycle). In his piece on newspapers, Steve Lewis writes, "Bottom-line and marketing-oriented decisions eviscerate the staffing, resources, and integrity that make newspapers what they are at their best." That same kind of thinking would never allow free and open source code to be written in the first place. Oddly, many companies today, especially large ones, look toward FOSS as a way to cheap out to replace costly stuff with cost-free stuff. They don't get what free and open code is really about, and how it works, and why you need to value (and support) its sources. This lack of understanding is very similar to that of newspaper owners who cut costs by junking their most valuable sources which are not the advertisers.
The success of FOSS requires that we start looking at the sources of sources: human beings, doing constructive work. What kind of public policies might grow on the realization that the sources that matter most are the people who comprise as well as build civilization? What kind of businesses? What kind of civic and public institutions?
There's a bottom here a foundation. But you can't necessarily see it from the bottom line of a company's balance sheet.
Doc Searls is Senior Editor of Linux Journal
I always considered that the
I always considered that the open code - is a step forward in civilisation development. Therefore I agree with the author of article.
Come on my site:
Yes, people are
Yes, people are infrastructure! ! !
S. Lewis
I tend to agree with what Stephen Lewis wrote. Very insightful.
Be careful with this
Newspapers are not infrastructure. They are frangible - a newspaper company is "easy" to set up, and one company can replace another which has lost its effectiveness and vision, or New Media forms (blogosphere) can replace newspapers. Rather, information flow is essential to free societies, whatever the means. "Health care" is also not infrastructure; doctors and their clinics come and go, organizations set up hospitals to meet a need. It isn't until the government decides something is infrastructure - and controls it - that it becomes "infrastructure". Like the telephone network, or gas/water/electric services in cities like Tucson, or "public" transit. The Internet is intrastructure in a sense like the telephone network, even though the backbones are largely company-financed and the protocols are free rather than centrally mandated. Do we want the Internet coopted by national governments, or the UN? Do we want the government to control (in any way at all) how Open Source is developed, and what gets developed, and by whom?
Users who script
Although you talk about coding, it is IT professionals who perform this service.
The users also create their own special purpose building blocks through the use of scripting applications. We all know the reason it is difficult for some commercial enterprises to migrate to Open Office that their user scripted macros don't work without a lot of fiddling, and maybe the original writers have left the company.
Beside OO macros, Linux supplies us with the ubiquitous shell, that wonderful tool used back in the last century by the clerks at Bell Labs to do their own information processing, which will be used again by a new breed of power users as Linux becomes one of the user's desktop tools of choice.
For these non coder mentalists, all that they require to complete their happiness is a scripted GUI builder to window their shells.
Once education starts, just imagine the explosion of independent ideas in your civilization.
I was really digging your point about humans ARE infrastruture.
I look forward to your future thoughts on inter-lockin'. I think that is the best feature of open source code. The way that linux plays nice with apache that plays nice with php, perl, python. Of course apache plays nice with tomcat which plays nice with linux and java. The phpBB plays nice with all of them. So does phpmyadmin and mysql.
This is an embarrassingly small list, but quite significant. With technologies like AJAX, we are poised for a completely new software landscape.
I may be defining inter-lockin wrong. so debug that if you wish.
But I really enjoyed your thoughts on the journalism metaphor. I consider open source to be a people powered movement, like the blogesphere (both right and left), and journalism, or at least what journalism should be. People-powered medicine has found cures for disease. People-powered engineering has built the brick and mortar institutions we have come to depend on. People-powered collective action defines democracy.
Look forward to hearing more, thanks
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Rain or Shine rips Ginebra
Alaska turns back Meralco
By Musong R. CastilloPhilippine Daily Inquirer
Even Yeng Guiao was surprised at how easy it was this time.
Rain or Shine pulverized Barangay Ginebra in a span bridging the middle two quarters last night and walked away with an 82-65 win for a 1-0 lead in their best-of-three quarterfinal series in the PBA Philippine Cup at Smart Araneta Coliseum.
And the Elasto Painters, who dropped their first two meetings with the Gin Kings in the eliminations, did it despite getting just three players in twin digits and with leading scorer Jeff Chan accounting for just a free throw for his lowest output in the conference.
"We did not expect it to be this easy," said Guiao later. "We played defense the way we planned to. The energy was high and everybody was active."
In the second game, Alaska held off Meralco, 90-84, to also take a 1-0 lead in their quarterfinal series.
"In a best-of-three, Game 1 is nothing," said coach Luigi Trillo, whose squad had comfortable leads in the third period but needed to fend off a Meralco comeback in the fourth. "We need to get back and focus on Game 2."
The Elasto Painters held the Gin Kings to just two points in the first six minutes of the third quarter for a 59-31 lead and were never threatened even if they scored just once for the remainder of the third quarter as Guiao started to clear his bench.
"We took care of business in terms of getting our share of the boards," Guiao continued. "It's also good that we were able to take out LA (Tenorio) and Mark (Caguioa) from their rhythm."
Caguioa finished with 16 and Tenorio had just six.
Jervy Cruz scored 14 points and had eight rebounds, Beau Belga was good for 11 and 11, and the comebacking Paul Lee had seven of his 11 points when the Painters broke away for good in the third.
The scores:
RAIN OR SHINE 82—Cruz 14, Lee 11, Belga 11, Matias 9, Norwood 8, Rodriguez 8, Quiñahan 8, Tiu 6, Tang 6, Chan 1, Uyloan 0, Jaime 0, Araña 0.
BRGY. GINEBRA 65—Caguioa 16, Jensen 13, Ellis 7, Tenorio 6, Hatfield 6, Maliksi 5, Espiritu 5, Helterbrand 3, Taha 2, Maierhofer 2, Labagala 0, Wilson 0, Mamaril 0, Wilson 0.
Quarters: 18-15, 39-29, 61-40, 82-65
Second Game
ALASKA 90—Baguio 26, Espinas 19, Dela Cruz 13, Thoss 10, Baracael 9, Abueva 6, Casio 5, Jazul 1, Hontiveros 1, Eman 0, Belasco 0.
MERALCO 84—Mercado 22,Cardona 14, Reyes 13, Ross 9, Hodge 8, Buenafe 7, Hugnatan 5, Nabong 2, Bulawan 2, Sharma 2, Borboran 0, Salvacion 0.
Quarters: 18-20, 44-33, 74-58, 90-84
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Learn how to bring big appeal to your knitting using only the tiniest of elements from best-selling author and knitwear designer Louisa Harding. Knitting in the Details explores different sets of embellishment methods through 24 small, quick-to-knit projects, from a beret with ribbon embroidery or a beaded scarf to a simple knitted vest with eyelets or a tank top with applique hearts. Additional variations and design tips highlight the boutique feel of each design, encouraging knitters to add their own personality to create a unique piece of knitwear.
Filled with inspiring project photography from the coast of France, Knitting in the Details evokes romantic femininity, and showcases how a project can be totally transformed by creative and well-placed embellishments.
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angry birds, space invaders, space, birds, angry, invaders, rovio, mash, up, nerd, geek, games, game, ipad, apple, nokia, vector, fun, funny, cool, color, colour, schytso, schytso designs, top selling, all time popular, best selling, best seller, all time best seller, all time best selling, funniest, coolest, most awesome, bigger, better, most popular
Clever design
Cheers buddy!
– Schytso Designs
Haha – nice one. You're the first to do this one mate! ;-)
Cheers mate, I just had to do this one! :)
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lol, nice.
Thanks a lot fixtape!
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On Monday morning, the Big Ten Conference announced its players of the week for Week 3. The honorees include four first-time winners, highlighted by Iowa's James Vandenberg, the Offensive Player of the Week. Vandenberg threw for 162 of his 399 passing yards and for all three of his touchdown passes in a remarkable fourth quarter to help Iowa tally its largest comeback in school history. The junior quarterback also added a rushing score, for good measure, as the Hawkeyes rallied from a 21-point deficit against Pittsburgh.
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Sulindac in Preventing Melanoma in Healthy Participants Who Are at Increased Risk of Melanoma
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
This randomized phase II trial is studying how well sulindac works in preventing melanoma in healthy participants who are at increased risk of melanoma. Sulindac may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether sulindac is more effective than a placebo in preventing melanoma in individuals with many moles and abnormal moles.
Condition | Intervention | Phase |
Precancerous Condition |
Drug: sulindac Drug: placebo |
Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Investigator) Primary Purpose: Treatment |
Official Title: | Phase II Trial of Sulindac in Individuals at Increased Risk for Melanoma |
- Sulindac Concentration in the Nevi (Moles) [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
- Sulindac Sulfone, an Active Metabolite of Sulindac, Concentration in the Nevi [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
- Sulindac Sulfide, an Active Metabolite of Sulindac, Concentration in the Nevi [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
- Sulindac Effects on Apoptosis in Atypical Nevi [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
- Sulindac Effects on Vascular Endothelial Growth Factor (VEGF) Expression in Atypical Nevi [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
- Association Between Plasma and Target Tissue Drug Levels [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
Enrollment: | 50 |
Study Start Date: | February 2009 |
Primary Completion Date: | October 2010 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: Sulindac
Participants receive oral sulindac 150 mg twice daily for 8 weeks in the absence of unacceptable toxicity.
Drug: sulindac
Given orally
Placebo Comparator: Placebo
Participants receive oral placebo twice daily for 8 weeks in the absence of unacceptable toxicity.
Drug: placebo
Given orally
Detailed Description:
I. Determine sulindac and sulindac metabolites (sulindac sulfone and sulindac sulfide) levels in healthy participants with atypical nevi (abnormal moles) and benign nevus at increased risk for melanoma treated with sulindac versus placebo.
I. Assess the effects of sulindac on apoptosis in atypical nevi of these participants.
II. Assess the effects of sulindac on vascular endothelial growth factor (VEGF) expression in atypical nevi of these participants.
III. Assess sulindac and metabolite levels in plasma and its association with drug levels in the target tissue.
OUTLINE: This is a multicenter study. Participants are randomized to 1 of 2 treatment arms.
- Sulindac arm: Participants receive oral sulindac 150 mg twice daily.
- Placebo arm: Participants receive oral placebo twice daily.
In both arms, treatment continues for 8 weeks in the absence of unacceptable toxicity.
Blood and tissue samples are collected at baseline and/or after completion of study therapy and analyzed for sulindac and metabolite levels via high performance liquid chromatography tandem mass spectrometry; the expression of the marker of apoptosis, cleaved caspase 3, and VEGF in atypical nevi was determined via immunohistochemistry assays.
After completion of study therapy, participants are followed for 2 weeks.
Ages Eligible for Study: | 18 Years to 65 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Healthy participants at risk for developing melanoma and meeting the following criteria:
- Must have ≥ 4 large (≥ 5 mm and < 15 mm) atypical nevi
- Must have 1 benign nevus amenable to biopsies
- No histologically confirmed melanoma on the baseline biopsy
No more than 1 prior cutaneous melanoma
- One prior stage I, IIA, or IIB melanoma allowed provided patients have been off treatment > 3 months
- No family history of melanoma involving ≥ 2 first degree relatives
- Modified dermoscopy score < 4.8
- Karnofsky performance status 80-100%
- White blood cell count(WBC) ≥ 3,000/mm³
- Absolute neutrophil count (ANC) ≥ 1,500/mm³
- Platelets count ≥ 100,000/mm³
- Total bilirubin ≤ 2.0 mg/dL
- Aspartate aminotransferase (AST)/alanine transaminase (ALT) ≤ 2.0 times upper limit of normal
- Creatinine ≤ 1.5 mg/dL
- Not pregnant or nursing
- Fertile patients must use effective contraception
- More than 6 months since prior and no concurrent tanning bed use or other methods to promote sun-tanning
- Willing to minimize sunlight exposure by applying sunscreen/sunblock or wearing clothing to shield skin during outdoor activity during study participation
- Willing or able to limit alcohol consumption to less than 3 servings a week during the study period
No frequent, chronic or moderate/severe gastrointestinal (GI) complaints including, but not limited to, any of the following:
- Upper GI problems requiring prescription or nonprescription medical remedies for symptoms of heartburn, dyspepsia, nausea, or abdominal pain > once a week on average
- History of peptic ulcer, occult or gross intestinal bleeding
- No prior allergic reaction to aspirin (unless subsequent dosing with other NSAIDs has been well tolerated)
- No history of allergic reaction to lidocaine or xylocaine
- No history of allergic reaction (e.g., urticaria, asthma, or rhinitis) or gastric intolerance attributed to compounds of similar chemical or biological composition to sulindac
- No history of bleeding or clotting disorder
- No invasive cancer or cancer treatment within the past 5 years, except nonmelanoma skin cancer
No immunosuppression by medication or disease, including any of the following:
- Oral prednisone
- Immunosuppressant/immunomodulator (i.e., cyclosporine, chemotherapeutic agent, or biologic therapy)
No uncontrolled intercurrent illness including, but not limited to, any of the following:
- Ongoing or active infection
- Symptomatic congestive heart failure
- Unstable angina pectoris
- Cardiac arrhythmia
- Psychiatric illness/social situations that would limit compliance with study requirements
- At least 3 months since prior and no concurrent coumadin or other systemic anticoagulant other than aspirin
- At least 30 days since prior participation and no concurrent enrollment or planning to enroll in another clinical trial
- No non-steroidal anti-inflammatory drugs (NSAIDs) for more than 5 days per month within the past 3 months and no concurrent non-study NSAIDs, except low dose aspirin (81 mg/day)
Willing or able to refrain from herbal medicines, above-standard vitamins, or minerals during study
- Standard daily multivitamin/mineral supplement (i.e., therapeutic doses of calcium and vitamin D for osteoporosis) allowed
- No concurrent lithium, phenytoin, or sulfonamides
United States, Arizona | |
Arizona Cancer Center at University of Arizona Health Sciences Center | |
Tucson, Arizona, United States, 85724-5024 | |
United States, California | |
Stanford Cancer Center | |
Stanford, California, United States, 94305-5824 |
Study Chair: | H. H. Sherry Chow, PhD | University of Arizona | |
Principal Investigator: | Clara Curiel, MD | University of Arizona |
Additional Information:
Responsible Party: | National Cancer Institute (NCI) |
ClinicalTrials.gov Identifier: | NCT00841204 History of Changes |
Other Study ID Numbers: | NCI-2009-01115, N01CN35158, UARIZ-08-0841-04, CDR0000633938 |
Study First Received: | February 10, 2009 |
Results First Received: | February 14, 2012 |
Last Updated: | March 21, 2013 |
Health Authority: | United States: Federal Government |
Keywords provided by National Cancer Institute (NCI):
precancerous condition |
Additional relevant MeSH terms:
Melanoma Precancerous Conditions Neuroendocrine Tumors Neuroectodermal Tumors Neoplasms, Germ Cell and Embryonal Neoplasms by Histologic Type Neoplasms Neoplasms, Nerve Tissue Nevi and Melanomas Sulindac Antineoplastic Agents Therapeutic Uses Pharmacologic Actions |
Cyclooxygenase Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Anti-Inflammatory Agents, Non-Steroidal Analgesics, Non-Narcotic Analgesics Sensory System Agents Peripheral Nervous System Agents Physiological Effects of Drugs Anti-Inflammatory Agents Antirheumatic Agents Central Nervous System Agents |
ClinicalTrials.gov processed this record on March 09, 2014


text:
Dynamics and functions of tight junctions
Dynamics and functions of tight junctions
Trends in Cell Biology, Volume 20, Issue 3,
Pages 142-149,
Publication Date 11 January 2010
Copyright © 2009 Elsevier Ltd All rights reserved.
DOI: 10.1016/j.tcb.2009.12.002
Emily Steed
Maria S. Balda
Karl Matter
Department of Cell Biology, UCL Institute of Ophthalmology, University College London, Bath Street, London EC1V 9EL, UK
Tight junctions are intercellular adhesion complexes in vertebrates that are required for the formation of functional epithelial and endothelial barriers. Their morphological appearance and biochemical composition, that includes large multimeric protein complexes, have long fostered the belief that they are relatively rigid, non-dynamic structures. Recent observations now suggest that at least some junctional elements and proteins can be very dynamic, and that such dynamic properties are important for different tight junction functions ranging from the regulation of paracellular permeability to junction-associated signalling mechanisms that guide cell behaviour. Combining such dynamic properties with existing tight junction models will help us to advance our understanding of the molecular mechanisms that underlie the functional properties of tight junctions.


text:
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Stock video footage described below includes pedestrians, sidewalks, streetscapes, a shoreline path, lightpole banners, urban mixed use areas, and downtowns. Of special interest are clips depicting pedestrians navigating a large urban center and views of charming sidewalk cafes in a small city.
For each group described below, the information provided includes number of clips, total running time, topical description, price, and still images. All groups on this page are available for preview online as QuickTimes (linked after each group below).
Clip Groups purchased royalty free are delivered as DV NTSC 720X480 QuickTime files on DVDs. Customers interested in purchasing groups of clips provided on DVDs as QuickTime files can get more information here.
The fastest, easiest, and least expensive way to purchase our clips is through Green Stock Footage. Many of our most requested individual clips are available 24/7 for online download at $19.95 each. Find out more here.
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Conference & Campus Speakers On Communities & Development Here >> Transportation & Mobility Here >> Living Urban Environment Here >>
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Genre: Sports Talk
Premise: Hosted by Bob Ley, ``OTL First Report'' was previously titled ``Outside the Lines Nightly'' and aired as a 20-minute show. In 2006 this investigative series got its own time slot to devote a full half-hour to investigating sports stories. Ley is frequently joined by correspondents Jeremy Schaap, Mark Schwarz and Kelly Naqi.
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Goals : •Drop to 160 #s and hold steady around that weight • Run 1st half marathon - Spearfish Canyon Half Marathon • Run 1st marathon - Mt Rushmore Marathon
Old age is when you move from illegal to prescribed drugs.
Courage ! Do one brave thing today...then run like hell.
Prince of Fatness
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Technical Data |
Antibiotic L-681,217 (L 681217) |
500ug |
Biochemicals | Storage: -20°CShipping: Blue Ice |
Antibiotic L 681,217 is a glycolipid-type antibiotic related to the efrotomycin class isolated from a Streptomyces sp. It inhibits bacterial protein synthesis at the elongation stage, its target being elongation factor Tu (EF-Tu). Antibiotic L 681,217 also shows broad spectrum antibiotic activity against gram-positive and gram-negative bacteria. Purity: >95% by HPLC Solubility: Soluble in methanol, DMF or DMSO. CAS Number: 93522-10-2 Molecular Formula: C36H53NO10 Molecular Weight: 659.8 |
Source: Streptomyces sp. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
1. Effects of elfamycins on elongation factor Tu from Escherichia coli and Staphylococcus aureus. Hall C.C. et al. Antimicrob. Agents Chemother. 1989, 33, 322. 2. L-681,217, a new and novel member of the efrotomycin family of antibiotics. Kempf A.J. et al. J. Antibiot. 1986, 39, 1361.


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Lovely Bright Studio available for immediate occupancy!
This beautiful light and bright residence is completely Gut Renovated includes Polished Oak Floors, Modern Kitchen with Granite Counters, Clean and Bright Bath with. Big windows for plenty of natural light, Ample Closet Space.
Young and vibrant area full of entertainment, theaters, restaurants, and gardens. Close to all public transportation.
Please call me to schedule a private viewing of this apartment.


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Cooperative Autonomous Driving: Intelligent Vehicles Sharing City Roads
File | Size | Format | |
31549.pdf | 2475Kb | Adobe PDF | View |
Title | Cooperative Autonomous Driving: Intelligent Vehicles Sharing City Roads |
Author | Baber, Jonathan; Kolodko, Julian Paul; Noel, Tony; Parent, Michael; Vlacic, Ljubo |
Editor | Kimon P Valavanis |
Year Published | 2005 |
Publisher | IEEE |
Citation | IEEE Robotics & Automation Magazine: Special Issue on Intelligent Transportation Systems, Vol. 12(1), pp. 44-49 |
Peer Reviewed | Yes |
Published | Yes |
Alternative URI | http://dx.doi.org/10.1109/MRA.2005.1411418 |
Copyright Statement | Copyright 2005 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE. |
Research Centre | Institute for Integrated and Intelligent Systems |
Faculty | Faculty of Engineering and Information Technology |
Publication Type | Journal Articles (Refereed Article) |
Please use this identifier to cite this record: http://hdl.handle.net/10072/4263
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Copyright in individual works within the repository belongs to their authors or publishers. You may make a print or digital copy of a work for your personal non-commercial use. All other rights are reserved, except for fair dealings or other user rights granted by the copyright laws of your country.


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April 29, 2013
SALT LAKE CITY, UT (April 27, 2013) - The picturesque snow-capped mountains of Utah served as the background for Round 16 of the Monster Energy AMA Supercross Series at Rice-Eccles Stadium in Salt Lake City but Chamber of Commerce 70-degree temperatures greeted race teams and fans, the best weather for an SX race this season. The racing circuit inside the outdoor college football stadium which serves as the home of the Utah Utes proved to be a major challenge for crew chiefs and riders. The extra-short straightaway between the starting gate and tight Turn 1 along with a racing surface filled with marbles and stones were factors in the Heat Races and Main Event. Josh Hill (No. 75 Dodge/Sycuan Casino/RCH Racing/Bel-Ray/Suzuki Z450) led the Dodge/RCH Racing team with a season-best finish of seventh in the Main Event. He raced inside the top 10 throughout the 20-lap feature. RCH Racing teammate Broc Tickle (No. 20 Dodge/Sycuan Casino/RCH Racing/Bel-Ray/Suzuki Z450) earned his 16th consecutive Main Event start of the season and finished 11th. Hill was seventh fastest in the afternoon timed practice and Tickle eighth. Both RCH riders used aggressive starts in their respective Heat Races to easily transfer to the Main. Hill finished third in Heat 2 while Tickle was fourth in Heat 1. In the Main Event, Hill was running ninth after the first lap. He moved into seventh on Lap 8 and maintained the position the rest of the race. "I got a decent start in the Main and made a few quick passes to gain some spots," Hill said. "I got up into the top 10 early and that helped. The race start was so hard if you were starting outside of the first few gates because it was such a short straightaway and tight left-hand turn. Guys would just bang into each other. Riders with the first eight gate picks chose the inside. It was a battle." Tickle looked to be on his way to his ninth top-10 Main Event finish until a mishap on Lap 10 in the tough whoops section dropped the RCH rider seven spots to 17th. The Michigan native raced the next nine laps incident free and battled his way back to 11th. "It was a solid start in the Main until I went down," Tickle said. "I was riding ninth and about to pass Andrew Short but skipped over a couple of the whoops and crashed pretty good. So I got up, got in behind (Trey) Canard and just started picking guys off that I had lost positions to earlier." The 2013 Monster Energy AMA Supercross Series season concludes next weekend in Las Vegas at Sam Boyd Stadium.
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For your safety, always wear a helmet, eye protection, and protective clothing when riding any motorcycle or ATV. Never ride under the influence of alcohol or other drugs. Study your owner's manual and always inspect your Suzuki before riding. Take a riding skills course. For the MSF street course nearest you, call 1-800-446-9227. Off-road riders can enroll in the DirtBike SchoolSM by calling 1-877-288-7093. ATV riders can call the SVIA at 1-800-852-5344 and we'll even pay for the training. Suzuki engineered the GSX-Rs™, Hayabusa, and the QuadSport Z400 for experienced riders.
Specifications, appearances, equipment, color, features, materials and other items of "SUZUKI" products shown are subject to change by manufacturer at any time without notice.
Suzuki, the "S" logo, and Suzuki model and product names are Suzuki Trademarks or ®. © Suzuki Motor of America, Inc. 2014.


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During his keynote speech at CES 2009 Microsoft's boss Steve Ballmer demonstrated a slate from HP meant to compete with the iPad.
Despite the hype, the gizmo was a train wreck. As a result, HP was forced to reboot the entire project due to bad initial impressions focused around sluggish performance and a huge hit that the underlying Windows 7 software took on its battery.
Fast forward to CES 2011 and there could be a second coming for Microsoft and its partners, a decade after Bill Gates first inaugurated his stylus-based tablet PC concept in 2001.
Of course, a lot has happened since then, except for one thing - Microsoft's resilience and determination to promote tablet computing powered by its Windows operating system.
And how do we know this?
Because knowledgeable sources who spoke to the New York Times on condition of anonymity say so, that's how.
According to a report published on the paper's Bits blog yesterday, Microsoft's chief will announce an array of Windows 7-driven slates and show off at least two of them on stage.
One, from Samsung, will have "a unique and slick keyboard that slides out from below for easy typing" and a custom user interface skin and the other will be built by Dell.
This time around, Microsoft's boss will allegedly showcase fully featured products instead of prototypes. As for a possible "one more thing" Jobs-esque moment, the paper hinted at the following possibility in Ballmer's keynote speech:
Another person with knowledge of Microsoft's plans said Steve Ballmer might demonstrate a tablet and other companion devices running the next operating system, Windows 8.
Before you flame us with angry comments, remember that we're just reporting here on other people's news.
Source: The New York Times' Bits blog
Thanks for reading BSN*


text:
CABINETS, RESIDENTIAL Cabinet Distributors Inc.
Building a new home, or remodeling what you currently have can be both an exciting and an unsettling time. There are dozens of decisions to make, often a great deal of money involved and you might even be living in the home while the work is being done. If there is one thing you can do right now to help your remodeling project go smoothly, it's this: Contact us and let us help you achieve the results you want.
At Cabinet Distributors, Inc. (CDI), we specialize in helping you create the kitchen, bath and other cabinet-use designs you want on time and within budget so you can enjoy the process and the end results.
We offer much more than cabinets, and create results that speak for themselves. Many builders work with us, too, because they know they can count on the quality products we represent and our consistently excellent service and follow-through.
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www.cabinetdistributors.com 5010 Lacey Blvd SE Lacey, WA 98503 (360) 493-1628 Fax (360) 438-0146 Cabinets, Residential


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The first Palestinian intifada (uprising or shaking off) erupted dramatically on 9 December 1987 after twenty long years of brutal Israeli military occupation. The Palestinians had had enough. Not only had they been dispossessed of their homeland and expelled from their homes in 1948 to make way for the boatloads of European Jewish immigrants flooding into Palestine on a promise of a Jewish state, they had been made to suffer the indignities of a people despised and rejected by the whole world. They were the victims of a colonialist project that denied their existence and their rights to self-determination in the land that they had continuously inhabited for millennia so that a state could be created in all of the land exclusively for Jews from anywhere in the world. To this day, the Zionist project has held powerful countries and august institutions hostage in its service, despite the indisputable rulings of international law and United Nations resolutions supporting the rights of the Palestinians. What Israel had not bargained for, though, was the steadfastness of a wronged people and their indomitable spirit that sent the first stones hurtling towards army tanks and bulldozers in their desperate bid to shake off Israel's crushing occupation. So began the "War of the Stones."
Today is the 24th anniversary of the 1st Intifada.
(via amodernmanifesto)
Source: fearandwar


text:
Beyond The Depth: Legends of Three Oceans is a multi-platform action adventure that tells the story of two daredevil friends as they travel the world hunting for sunken treasures. But what friends do not know is that they are about to find themselves in the middle of an ancient legend that comes true!
Taking place in six areas scattered all over the globe the game is full of attraction from survival and predator fights to interesting puzzles and mini-games. And thanks to Facebook integration you will be able to share your treasure hunt progress with friends straight from the game menu!
Beyond The Depth features a highly realistic, diverse and amazingly beautiful underwater world and marine wildlife thanks to the fact that it was created using powerful and versatile (3d Engine technology) developed by Biart and powered by NVIDIA PhysX. biEngine allows to create high fidelity visuals on various platform from iOS and Android to Xbox 360 and PlayStation 3. In addition to this, on the PC platform the Biart's 3d Engine technology has built in support for NVIDIA 3D Vision allowing for fantastic stereoscopic experience.
Hidden treasures, adventures and beauty of the underwater world are waiting in Beyond the Depth: Legends of Three Oceans!
Game Features:
- Interesting story, amazing ambience and thrill of underwater adventure!
- Puzzles with underwater physics, unique mini-games including hidden object games
- Realistic, high fidelity 3D world with 6 huge locations around the globe and support for NVIDIA 3D Vision
- Game world so realistic that you will learn about real coral reefs and marine wildlife by playing the game!
- Different game modes: diving, treasure hunt, crab hunting, underwater photo hunt
- Built-in marine wildlife encyclopedia!
Target Platforms:
- Apple iOS
- Android
- PC: Windows 8 with touch controls, Windows 7
Official site - http://www.beyondthedepth.com