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The List
Unclenched Fists
When it comes to foreign policy, these are the six most significant inaugural addresses in U.S. history.
The presidential kick-off speech holds a special place in the American imagination. From Abraham Lincoln's second, dramatized in this year's Steven Spielberg movie starring Daniel Day-Lewis, to Franklin D. Roosevelt's first, immortalized by the line, "The only thing we have to fear is fear itself," the inaugural address has achieved mythical status in America. (Whole books have been written about John F. Kennedy's 1961 address -- a speech that was exactly 1,363 words long.) Interestingly, however, very few of the 56 inaugural speeches delivered to date have devoted much time to foreign policy.
Instead, most presidents have used their inaugurals to set out their domestic policy agendas. George Washington in 1789 warned of "party animosities" and extolled the virtues of "rectitude" and "patriotism"; FDR in 1933 called for wartime powers ... to fix the failing economy; and Ronald Reagan in 1981 laid out his vision for limited government. "[G]overnment is not the solution to our problem; government is the problem," he declared in one of the speech's most memorable lines.
In his second inaugural, Barack Obama will almost certainly follow their lead. Economic recovery and the need to end partisan bickering are likely themes for his speech, as is the scourge of gun violence, which will probably get a line or two. But on the off chance that Obama decides to make a major foray into foreign policy, here's a list of six inaugural addresses that have done so in the past. The first he'll probably remember, since he delivered it four years ago.
After an election that was fought in large part over America's role in the world, Obama used the occasion of his first inaugural to signal a new beginning in dealings with friends and foes alike. In an explicit rebuke of George W. Bush's era of unilateralism, Obama reminded Americans that past generations defeated fascism and communism "not just with missiles and tanks" but with "sturdy alliances." He also reached out to the Muslim world, where anger over the Iraq war still simmered and an aging cast of dictators had grown weary of the Bush administration's demands for political reform. "To the Muslim world, we seek a new way forward based on mutual interest and mutual respect," Obama said.
But the most memorable line of the address was directed implicitly at Iran -- ringleader of Bush's "Axis of Evil" -- which remained hell-bent on acquiring nuclear weapons while repressing its own people. "To those who cling to power through corruption and deceit and the silencing of dissent, know that you are on the wrong side of history," he said, "but that we will extend a hand if you are willing to unclench your fist." The Iranians were evidently unimpressed. The next day, a spokesman for Supreme Leader Ayatollah Ali Khamenei fired back that "Obama's is the hand of Satan in a new sleeve." Iranian President Mahmoud Ahmadinejad, for his part, opined that "the Great Satan now has a black face."
Obama's conciliatory tone played better among American liberals, who lauded the president for "breaking with the past," but it gave conservatives plenty of political ammunition when his subsequent overtures were rebuffed.
Four years after he vowed to build a more perfect democracy at home in his first inaugural address, Bush took his ambitious message global, delivering a lengthy paean to freedom that put dictators everywhere on notice that they were now in the crosshairs. "Today, America speaks anew to the peoples of the world. All who live in tyranny and hopelessness can know: The United States will not ignore your oppression or excuse your oppressors. When you stand for your liberty, we will stand with you."
Delivered just as Iraqis were preparing to elect a transitional government, Bush's speech made clear that democracy promotion would be the central pillar of American foreign policy in his second term. The "forward strategy of freedom in the Middle East" -- laid out in a 2003 speech at London's Whitehall Palace -- had morphed into a global project aimed at engineering a democratic peace. In Bush's words:
"The survival of liberty in our land increasingly depends on the success of liberty in other lands. The best hope for peace in our world is the expansion of freedom in all the world.... So it is the policy of the United States to seek and support the growth of democratic movements and institutions in every nation and culture, with the ultimate goal of ending tyranny in our world."
The speech received mixed reviews even among conservatives. Wall Street Journal columnist Peggy Noonan wrote that it left her "yearning for ... nuance," while liberal responses ran the gamut from "startling" to "the most un-American speech I've ever heard."
Just five days after he ordered the end of a massive bombing campaign in Hanoi and Haiphong, and seven days before he actually signed the Paris Peace Accords, Richard Nixon took the podium on the Capitol's East Portico and delivered a rousing encomium to peace. "As we meet here today, we stand on the threshold of a new era of peace in the world," he crowed. "The central question before us is: How shall we use that peace?"
"Let us resolve that this era we are about to enter will not be what other postwar periods have so often been: a time of retreat and isolation that leads to stagnation at home and invites new danger abroad.... This past year saw far-reaching results from our new policies for peace. By continuing to revitalize our traditional friendships, and by our missions to Peking and to Moscow, we were able to establish the base for a new and more durable pattern of relationships among the nations of the world. Because of America's bold initiatives, 1972 will be long remembered as the year of the greatest progress since the end of World War II toward a lasting peace in the world."
Many saw the speech as deeply cynical, given that the president arguably could have ended the Vietnam war four years earlier on similar terms, and the following day's New York Times noted Nixon's glaring omission of the words "Vietnam" and "Indochina." But the California Quaker evidently saw himself as a peacemaker -- and branded himself as such when he re-entered public life in the post-Watergate era. His tombstone in Yorba Linda, Calif. is inscribed with the following epitaph: "The greatest honor history can bestow is the title of peacemaker."
One of the most famous addresses of all time -- up there with FDR's 1933 "nothing to fear" speech and Lincoln's 1865 "malice toward none" masterpiece -- Kennedy's only inaugural address is remembered primarily as a call to service. ("Ask not what your country can do for you, but what you can do for your country," is easily the most famous line.) But the speech's deeper significance lies in the fact that it challenged the prevailing run-for-the-bunker Cold War mentality, conveying both American resolve and willingness to negotiate.
Parts of the speech are hawkish, like the section that declares, "We shall pay any price, bear any burden, meet any hardship, support any friend, oppose any foe to assure the survival and the success of liberty." But other moments are pragmatic, even conciliatory. "Let us never negotiate out of fear. But let us never fear to negotiate," he said, suggesting further that both the Soviets and the United States "formulate serious and precise proposals for the inspection and control of arms." Kennedy also called the United Nations "our last best hope," vowed to alleviate global poverty, and affirmed his commitment to U.S. allies, remarking that "United, there is little we cannot do in a host of cooperative ventures. Divided, there is little we can do."
The following day, the New York Times lauded Kennedy's theme of "conciliation without weakness," noting that the speech "entirely lacked the polemical tone and defensive outlook that have characterized many American state papers in recent years."
With the Axis tearing Europe apart and threatening to dominate the rest of the free world, FDR delivered a powerful statement for the preservation of democracy in his third inaugural address. The United States was not yet at war -- Pearl Harbor would not be attacked for 11 more months -- but it was in the midst of a global crisis. So great was the sense of peril that Roosevelt felt the need to declare at one point, "No, democracy is not dying."
"The democratic aspiration is no mere recent phase in human history. It is human history," he said, before tracing the lineage of the American "spirit" from the Magna Carta to the Mayflower Compact and all the way to the Gettysburg Address. The existential threat of war did not yet demand American intervention, FDR implied, but the United States must not revert to the kind of isolationism that people like Charles Lindbergh were advocating. "In the face of great perils never before encountered, our strong purpose is to protect and to perpetuate the integrity of democracy," he said. "We do not retreat. We are not content to stand still. As Americans, we go forward, in the service of our country, by the will of God."
Perhaps because of its abstract and philosophical tone, the address failed to rouse the crowd gathered on that cold January morning in 1941, and FDR told his advisors afterwards that he was disappointed with the speech. Prior to the inauguration, FDR had delivered two major addresses: a Dec. 29 fireside chat in which he declared that "we must be the great arsenal of democracy" and his famous "Four Freedoms" speech on Jan. 6. As a result, he felt the country was fed up with long pronouncements from its leader and settled on a shorter address. But the speech was of a piece with the campaign waged by FDR in late 1940 and early 1941 to pass the Lend-Lease Act and to place America more firmly on the side of Britain in the unfolding war. In that effort, he faced vehement opposition from isolationists in Congress. By casting the war as a fight for democracy, FDR boldly dared his political opponents to undermine an effort to rescue that dearly held American ideal.
Remembered primarily as a call for unity in the aftermath of a divisive political campaign, Jefferson's first inaugural address was mostly concerned with politics at home. He emphasized the importance of majority rule, minority rights, and the peaceful transfer of power -- reminding Americans that "every difference of opinion is not a difference of principle."
But Jefferson also held forth on the question of America's role in the world. He called for "peace, commerce, and honest friendship with all nations," but "entangling alliances with none." The latter clause, quoted endlessly by isolationists, has been taken to mean that the United States should eschew international commitments and focus only on its own affairs. But Jefferson wasn't interested in cutting America off from the world -- his commitment to global commerce betrayed his internationalism. Still, he did not lament the fact that the United States was "kindly separated by nature and a wide ocean from the exterminating havoc of one quarter of the globe."
Jefferson's election in 1800 -- sometimes referred to as the Revolution of 1800 -- marked the arrival of the United States as a democratic power and the first instance of a peaceful transition of power from one party to another. But if Jefferson's embrace of commerce was supposed to have signaled the country's arrival as an economic power, the condition of the capital during his inauguration revealed his country's youth. Legislators huddled in the corridors of the Capitol were frequently disturbed by the sound of gunfire from quail hunters a few hundred yards from the still-unfinished building. The inauguration, in fact, may have been held in the Senate chamber because it was one of the few public spaces in the capital that had been completed by 1801. And while Jefferson's arrival at his inauguration without the grand retinue on display at Washington and Adams's inaugurations has become part of the democratic mythology surrounding the third president, his simple entrance could just as easily have been a function of the fact that Pennsylvania Avenue was still littered with tree stumps at the time.


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Graduate School:
Applying to graduate school can be an arduous process, so it's important to start early to ensure you don't miss any deadlines. Deadlines and admissions requirements vary by school, so it's important to identify and narrow down potential choices approximately 6-12 months before application. These links can help you identify which schools offer specific programs in a particular geographic location.
It is also recommended you talk with faculty members and your advisor about your graduate school search and inquire to them about graduate schools they recommend. You should visit the website of each school you are interested in, review the admissions requirements, curriculum, graduation requirements, and faculty biographies to determine which schools might be right for you.
Admissions Tests:
MCAT: https://www.aamc.org/students/applying/mcat
GRE General Test: https://www.ets.org/gre/
GRE Subject Test: http://www.ets.org/gre/subject/about
GMAT: http://www.mba.com/the-gmat.aspx
PCAT: http://www.pcatweb.info/
DAT: http://www.ada.org/dat/aspx
OAT: https://www.ada.org/oat/index.html
The following test centers are located in Sioux City, IA:
Personal Statement:
The requirements for a graduate school personal statement will vary by program, however, there are some overall themes are applicable to most any personal statement or essay.
Please schedule an appointment with your academic advisor or Career Services to get targeted advice on your personal statement.
Letters of Recommendation:
Most schools will require anywhere from 2-5 letters of recommendation. Oftentimes, the recommenders will need to be specifically identified (ie; chiropractor programs require one letter from a chiropractor). Other good sources of letters of recommendations could come from professors, academic advisors, organizational advisors, or even coaches. Basically, the writer of the letter should know you well enough to communicate to the admissions committee that you have the academic capability, as well as strong personal characteristics that would make you successful in graduate school. With this in mind, please choose your recommenders wisely.
You also must ask any recommender to write you a letter in a professional and appropriate way. Here are a couple of tips:

subset: commoncrawl


text: | The Freeman Ranch is a 3,500-acre working ranch located off County Road 213, via Ranch Road 12, just outside of San Marcos. The ranch serves as an educational laboratory and research base for many Texas State faculty and students, as well as the site of many special university events. |


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Product Details:
This USB Notebook Cooling Pad prevents your laptop from getting too hot and keeps it running properly! An overheated laptop can lead to a number of inconvenient and costly problems, including burnt-out processors, sluggish performance and battery fires. The laptop cooler is just the one you need to keep your notebook cool! |


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Women's Soccer to play for KIAC Title
BEREA, Ky. – Asbury will play for their fifth straight KIAC Tournament Championship on Saturday afternoon after defeating Brescia 7-0 on Friday night. The Eagles were led by senior Bethany Russell's first career hat-trick.
Asbury will take on Cincinnati Christian on Saturday at 1:00 pm at Berea. CCU defeated Mountain State in Friday's other semi-final. Asbury defeated CCU in their only regular season match-up 3-1 back on October 27th in Wilmore. The winner will earn a berth to the NAIA Opening Round to be played at a campus site on November 20th.


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The Texas Freshwater Fisheries Center is holding Fly Fish Texas! 2014 on March 8 in Athens. Fly-fishing clubs and anglers from across the state will share tips and techniques.
Find hundreds of happenings all across the state on our Events page.
See the Table of Contents for links to this issue's stories, recipes, Letters to the Editor and more.


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Found December 23, 2012 on
Basketball fans everywhere have been wanting to see Miami Heat forward LeBron James show off his impressive dunking skills and compete in the Slam Dunk Contest during the NBA All-Star weekend. Ever since James came into the league nine years ago his name has been brought up as a potential competitor in the contest. But the speculation of James ever competing ended after Saturday night's 105-89 Heat
Original Story:
Video: Miami's LeBron James and Dwyane Wade star in hilarious animated clip
Johnny Manziel, Lebron James, and a demon-eyed Longhorn fan.
Ray Allen is renting a Miami beachfront home for $50,000 a month
Wade, LeBron Connect On Full-Court Pass
LeBron James says he could lead NBA in scoring if he wanted
LeBron James: "If I Wanted To, I Could Lead The League In Scoring"
Could LeBron Return To Cavaliers In 2014?
Russell Westbrook channels 70′s fashion for GQ spread
Jeremy Evans: I Would Beat LeBron In Dunk Contest
The Miami Heat's Lebron James, and Los Angeles Clippers' Chris Paul named Players of the Week
LeBron, Paul Named Players Of The Week
Russell Westbrook would like to enter the dunk contest (eventually)
NBA Forum Discussions
1 replies,
2 days ago
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> select price
Flower Arrangement
$40.00, $50.00, $60.00Flower Arrangement
Shown at $50.00
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Included in This Arrangement
Black Plastic Design BowlWet Floral Foam
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Twin Culvert Cave Nature Preserve
Pike County
Location and Access:
2 miles southwest of Pearl. Part of Sec. 17, T7S, R2W, 4 PM.
Natural Features:
Cave of the Driftless Section of the Middle Mississippi Border Natural Division.
Owner and Custodian: The Nature Conservancy, 8 S. Michigan Ave., Suite 900, Chicago 60603 (312/346-8166).
Dedicated: July 1999
Size: 5.0 acres
Topo Map: Pearl 7.5
1/2009 - R. Heidorn


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Go wine tasting in British Columbia's Okanagan Valley
This achingly beautiful wine country is in full-throttle discovery mode, with new wineries and different kinds of grapes going
in all the time ― nearly 60 varietals, planted all over the benchlands, hillsides, and valley floor.
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(from riding the century-old Kettle Valley steam train to biking and hiking), and you have a wine-country experience like
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More: Your guide to the Okanagan Valley
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Product Description
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Customers' Reviews
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from (Seattle)
Bought this item on
12-06-2013- Pros: It's a beanie.
- Cons: I had loved the first dark gray I ordered from them a while ago but it was fading a bit. I ordered the same and apparently they send out whatever they feel like...
- Other Thoughts: ...It doesn't resemble the picture or what I already have. It's also heavier and smaller. DD's "Bottom Line" makes yes the only review choice. Mine is really a NO.
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from (NL)
Bought this item on
05-22-2012- Pros: Great Quality for the price, I have seen this kind off hats for much more on other sites, so it is definitly a good deal.
- Cons: Nothing bad to say about it
- Other Thoughts: I use it for rainy or cold days during the summer.
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03-16-2012- Other Thoughts: Not much to say here- it's got an interesting texture, it's a comfy hat and enjoyable to wear. I'm loving this hat, keeps my head nice and warm. Looks good, feels good.
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03-06-2012- Other Thoughts: Very nice and comfortable - good quality cotton and long lasting. I bought this and at first I was very pleased because of the price and what I wanted.
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02-23-2012- Other Thoughts: Just what I was looking for: a pure black beanie that's not uncomfortable and itchie.
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02-19-2012- Other Thoughts: I love this Beanie. Is very comfy and thick, and gets the job done, I wore it all winter, it just feels so good. I wish all my clothes were this good.
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Bought this item on
02-06-2012- Other Thoughts: This Cotton Beanie is great. High quality fabric and weave, keeps my head warm, folds nicely, and cleans well. Great stuff! Keep in mind, it may require rolling a bit if you have a tiny head.
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from (Hyderabad, India)
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from (Japan)
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01-16-2012- Other Thoughts: This is a quality hat. Not too large (long) - you know so it doesn't have to be folded over and it goes just about right down the ears and forehead. The cotton is great. It feels good, and color is great.
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I was walking along Jones Street in the Tenderloin the other day when the former director of a neighborhood advocacy group chased me down to deliver a desperately urgent message: I absolutely had to eat lunch at Stix Roadhouse.
Figuring that, if nothing else, I would never again have an opportunity to begin a restaurant review in such a manner, I pressed him for details. Stix Roadhouse, he said, has become his new favorite haunt. He promised huge salads and gigantic, well-made sandwiches, and added that the place also featured "cafe prices and downtown quality," and, as an added bonus, a view of the driving range in the sunny Mission Bay Golf Center.
As luck would have it, my girlfriend and I were taking a road trip a few days later, and, figuring that no journey should begin on an empty stomach, we dropped by the Roadhouse on a Friday afternoon to see if his tip would pan out. Located near the Mission Creek houseboat colony, just a hop, skip, and a jump from soon-to-open Pac Bell Park, Stix Roadhouse looks remarkably like ... a roadhouse, a sort of open-air, barn-type structure with sliding glass doors and a corrugated, fiberglass roof.
Out front, a half-dozen or so duffers milled about, looking purposeful with their golf bags chock-full of drivers and wedges. Inside, sunlight poured through the roof onto neat blue-and-white checkered tablecloths, giving the place a festive air. Had it been a tad more shady -- and, say, located on a stretch of lonely highway somewhere east of San Bernardino during the 1970s -- Stix would have been the kind of place where Hell's Angels rode their Harleys across the bar, downing pitchers of Miller as they pawed at the waitresses and picked the bugs from their beards. But this, of course, was San Francisco in the late 1990s, and patrons seemed to lean more toward happy-hour revelry than chain fighting, a vibe codified by the following slogans, set in succession on the rafters:
Work like you don't need the money.
Dance like nobody's watching.
Love like you've never been hurt.
If only.
Having already journeyed a good two or three miles, my girlfriend and I were famished by the time we sidled up to the counter and scanned a very promising menu that featured sandwiches, salads, pizzas, and a handful of daily specials. The average cost of an entree hovered at around seven bucks -- Hot damn, I cried out, these were some cafe prices. As for the downtown quality I'd been promised, well, we'd just have to see about that. But with 330 miles to go before we slept, I figured we'd do best to load up on the grub, ordering an iced tea ($1.25) for the lady, a Sierra Nevada ($3) for myself, and, to wash it down, an eight-course lunch that would have put the most potbellied truck driver in Texas to shame.
We made our way to a spacious deck whose trellis was hung with passion vine, took a table with a view of the putting green, and waited for our number to be called. At Stix Roadhouse, you walk up and get your own dang food -- which may or may not be a roadhouse tradition, but then again, I'm no roadhouse expert. Interstate 280 curved past us in the distance, its soft hum interrupted by the sharp smack of golf balls being driven toward the horizon. In addition to daily happy-hour specials (e.g., Tap Tuesdays -- $2 draft beers from 4 to 8 p.m.), Stix also offers half off on a bucket of balls with the purchase of a meal and beverage over $6.50, which I would advise as a means of burning off the excess calories generated by what proved to be some hearty, roadhouse portions.
We began with a pair of small tossed salads -- the Jackie Chan ($5.95) and the Louis salad ($5.95). As they appeared before me on the counter, I asked what is undoubtedly a common question at Stix: That's a small?A delightful medley of sesame chicken, julienned red bell peppers, and crunchy fried wontons perched on a heaping pile of greens, the Jackie Chan featured a delicate hoisin dressing and could have been a meal in itself. The Louis came with jumbo shrimp, cherry tomatoes, whole black olives, and a half-avocado smothered in -- what else? -- Louis dressing.
Next, we sampled a cup of chili con carne ($2.95), which looked more like a bowl and was topped with fresh salsa and a dab of sour cream. The sandwiches were also generously sized -- like either of the salads, the "fish stix" sandwich ($6.95) with a side of potato salad could have easily been a meal in itself. An ample fillet of grilled salmon on focaccia with lettuce, tomatoes, grilled onions, and a tangy piccata mayonnaise, it definitely delivered on the "downtown quality" part of my acquaintance's promise.
Moving on to heartier fare, we tore into the roadhouse's "famous" four-star cheeseburger ($5.95), a monstrous, 17-pound burger (OK, maybe it was only a half-pound) made of beef ground right there on the premises. Served on focaccia, the cheeseburger was topped with provolone and featured a side of 100 percent fresh potato french fries. I added a dab of Grey Poupon and decided that this was, in fact, better than downtown quality: It was uptown. We stacked our empty plates one atop the other, our eyes burning with ferocity, and moved on to the main course: a braised zinfandel lamb stew ($7.95) with a side of garlic mashed potatoes.


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Blaq Poet (Feat. MC Eiht and Young Malay) - Ain't Nuttin' Changed (Queensbridge To California Remix)Description: ideo is for the remix to Blaq Poet's first single from his forthcoming album, Tha Blaqprint. The song features west coast legends MC Eiht and Young Malay in addition to a brand new verse from Blaq Poet himself. The song is produced by the legendary DJ Premier, who is also featured in the video. |
Total Views : 116,665 Video Added : 2009-06-24 Video Code:
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I am irresponsible enough when it comes to ordinary fudge, and by irresponsible I mean that whenever it is in the house, I sidle on by and shave off slivers of it (it's just a sliver! how bad could that be?!) until there is no fudge left.
I take pretty much the same general approach with candy corn. (Just one! Just three! Just…ten!) And so when I fell for this recipe I immediately packed up the entire thing and sent it down to the teenager so she could share it with her millions of college buddies.
Well, almost the entire thing. Pretty close to the entire thing. Very close. I know you believe me.
Anyway….this is fudge that is pretty much the standard fudge recipe you know and love. Marshmallow creme, evaporated milk, sugar, semi-sweet chocolate…but with candy corn. It's a quick and easy recipe…honestly, the hardest part of the whole thing is getting the dang marshmallow creme (or fluff, as we like to call it) out of the jar. That stuff hangs on for dear life.
Anyway, devilishly good candy corn fudge…just in time for Halloween! All treat, no tricks.
- Candy Corn Fudge,adapted from My Recipes
1 7-oz. jar marshmallow cream1 1/2 cups sugar2/3 cup evaporated milk2 tablespoons unsalted butter2 cups candy corn (about 12 oz.)1 cup semisweet chocolate chipsDirections
1. Line an 8-inch square pan with foil; butter foil. Combine marshmallow cream, sugar, evaporated milk and butter in a large, heavy pan. Bring mixture to a boil over medium-high heat. Cook, stirring constantly, until mixture reaches 235°F on a candy thermometer, 10 to 15 minutes.2. Remove from heat and stir in candy corn and chocolate chips, stirring until chocolate melts. Immediately transfer to foil-lined pan and smooth top until even. Chill until set, at least 2 hours. Cut into one inch squares and give away immediately so you don't eat it all yourself!


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NEW YORK - JANUARY 21: Actress Sigourney Weaver participates in a question and answer session following SAGIndie's screening of "Prayers for Bobby" at American Academy of Dramatic Arts on January 21, 2009 in New York City. (Photo by Rob Loud/Getty Images) *** Local Caption *** Sigourney Weaver
UPLOADED ON 2009-01-22 00:10:30 PHOTO BY Getty Images
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12 September 2012
The Wind River Intelligent Device Platform is a complete software development environment for M2M applications with support for the new Intel Intelligent Systems Framework. It contains security features designed for M2M development, smart and connected capabilities and validated and flexible device management software. The core of the platform is a layer that contains configuration and build information for integrating other M2M components to generate an optimised, functional run-time image. Santhosh Nair, general manager of intelligent systems group at Wind River, commented: "Connectivity, security, optimisation and adherence to industry standards are required in order to successfully develop smart connected devices and services, and this is precisely the value that Wind River brings to the table. This platform maximises the value of M2M technology by building on an integrated foundation of software, middleware and board support packages with cutting edge tools and development environments."
Laura Hopperton
Websites http://www.windriver.com
Companies Wind River UK Ltd
This material is protected by Findlay Media copyright See Terms and Conditions. One-off usage is permitted but bulk copying is not. For multiple copies contact the sales team.
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Aubagio EU Backing Comes With Generic WorriesEP Vantage • Mar. 25, 2013
New Reasons To Be Bullish On SanofiTrading Maven • Nov. 6, 2012
at CNBC.com (Feb 6, 2014)
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at CNBC.com (Jan 31, 2014)
at MarketWatch.com (Jan 24, 2014)
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SNY vs. ETF Alternatives
Company Description
Sanofi is a healthcare company focused on patient needs and engaged in the research, development, manufacture and marketing of healthcare products. The Company also discovers, develops and distributes therapeutic solutions.
- All
- | Earnings
- | Dividends
- | On the move
Monday, Mar 1010:00 AM
- The WSJ profiles "pharmaceutical scouts," who, like talent-spotters in baseball "trying to pick tomorrow's big-leaguers from farm teams," search outside their companies to find drug candidates that have the potential to become blockbusters.
- In 2011, for instance, Johnson & Johnson's (JNJ) Peter Lebowitz helped his company beat competitors such as Novartis (NVS) to buy the rights to a blood-cancer drug from Pharmacyclics (PCYC) called Imbruvica.
- The treatment was eventually approved in November for a rare lymphoma and for chronic lymphocytic leukemia in February. J.P. Morgan forecasts Imbruvica will generate $1.3B in revenue for J&J in 2017.
- Half of J&J's drug pipeline is from outside the company, up from 20% in 2002.
- Other related tickers: MRK, RHHBY, BMY, SNY, CELG, GSK
Monday, Mar 1010:00 AM| Comment! -
Friday, Mar 74:24 PM
- The FDA requests that Regeneron (REGN) and Sanofi (SNY) assess potential neurocognitive side effects of their late stage cholesterol drug alirocumab, a PCSK9 inhibitor.
- Memory loss, impaired concentration and paranoia, though rare, have been associated with the use of statins for lowering LDL cholesterol.
- Both firms disclosed in their regulatory filings that the appearance of these side effects could delay or stop the product's development.
- Pfizer (PFE) and Amgen (AMGN) are also working on PCSK9 inhibitors.
Friday, Mar 74:24 PM| 5 Comments -
Wednesday, Feb 269:43 AM
- Anika Therapeutics (ANIK) surges 41% to $48.67 following the FDA's approval of the company's Monovisc single injection for pain caused by osteoarthritis of the knee.
- The authorization must feel pretty sweet for Anika - it first applied for approval over four years ago.
- Summer Street has hiked its price target to $60 a share from a prior PT of $47.
- "We believe this product will be competitive in a market that is becoming more focused on single-shot injections," Summer Street says.
- There are 27M people in the U.S. who suffer from osteoarthritis, which occurs when cartilage breaks down in joints, causing pain and stiffness as bones rub together.
- Sanofi (SNY +0.1%) and Zimmer (ZMH +0.4%) sell rival products.
Wednesday, Feb 269:43 AM| Comment! -
Tuesday, Feb 258:32 AM
- Sanofi (SNY) has licensed the development rights to a portfolio of preclinical kidney-disease drugs from California-based biotech Ardelyx.
- Sanofi will pay an undisclosed up-front payment, milestones of as much as $198M and royalties on any products. (PR)
Tuesday, Feb 258:32 AM| Comment! -
Monday, Feb 1012:47 PM
Thursday, Feb 64:29 AM
- Sanofi (SNY) Q4 adjusted, or "business net profit" rose 17% to €1.81B, coming in slightly below consensus of €1.82B.
- Net sales dropped 0.8% to €8.46B.
- Net profit jumped to €1.06B ($1.43B) from €388M a year earlier.
- Earnings were boosted by double-digit growth in sales of Lantus, Sanofi's blockbuster diabetes drug, revenue growth at its Genzyme rare-diseases unit, and a gradual recovery in Brazil and China. Cost cuts also helped.
- However, falling revenue from Sanofi's vaccines and animal health units, and currency fluctuations, hurt the firm's performance.
- The company expects business EPS to increase 4-7% at constant exchange rates in 2014, boosted by its "growth platforms" and new drug authorizations. It helps that Sanofi is beyond its patent cliff.
- Sanofi declared a dividend of €2.80 a share for 2013 vs €2.77 in 2012. (PR)
Thursday, Feb 64:29 AM| Comment! -
Tuesday, Feb 48:28 AM
- Ten major pharmaceuticals companies are getting together with the National Institutes of Health and other organizations in a five-year partnership that will look to understand the science behind Alzheimer's, Type 2 diabetes, rheumatoid arthritis and lupus.
- In an unusual move, the normally secretive participants will share scientists, tissue, blood samples and data, with the aim being to identify targets for new drugs.
- The firms involved include Bristol-Myers Squibb (BMY), Johnson & Johnson (JNJ), GlaxoSmithKline (GSK), Takeda (TKPHF) and Sanofi (SNY).
- Those that haven't joined include Amgen (AMGN), Roche (RHHBY) and AstraZeneca (AZN).
Tuesday, Feb 48:28 AM| 4 Comments -
Friday, Jan 317:40 AM
- Sanofi (SNY) has sued Eli Lilly (LLY) over the alleged infringement of patents related to the French company's top-selling Lantus diabetes treatment.
- Sanofi's action comes a month after Lilly filed for FDA approval to sell a biosimilar version of Lantus and questioned the validity of several of its patents.
- Sanofi's suit has triggered an automatic 30-month stay of approval by the FDA, which means Lilly won't be able to market its biosimilar drug until mid-2016, over a year later than previously expected.
- Lantus generates worldwide revenue of $7B but is due to lose patent protection in the U.S. in February 2015.
- Sanofi's shares were -1.7% premarket, while those of Novo Nordisk (NVO), another major provider of insulin products, were +3.3%.
Friday, Jan 317:40 AM| 1 Comment -
Tuesday, Jan 1412:43 PM
- Roth Capital is out with a bullish note on Regeneron (REGN +9.1%) on the heels of the company's announcement of a new development agreement with Bayer.
- Here's analyst Joseph Pantginis, commenting: "Preclinical studies have suggested that blocking both PDGFR-beta and vascular endothelial growth factor (VEGF) can provide additional benefit over anti-VEGF treatment (such as EYLEA) alone in wet AMD."
- Buy rating maintained.
- Price target is $362.
- In other company news, REGN has announced a collaboration with Geisinger Health System under which the companies will "study the genetic determinants of human disease." Additionally, Sanofi (SNY) has amended its investor agreement with REGN and retains the right to "acquire up to 30% of REGN's outstanding common stock and Class A stock [while gaining] the right to nominate a single independent director to the Regeneron Board of Directors upon reaching 20% ownership [stake]."
Tuesday, Jan 1412:43 PM| 3 Comments -
Monday, Jan 133:29 AM
- Sanofi (SNY) has agreed to acquire a 12% holding in Alnylam Pharmaceuticals (ALNY) for $700M in a deal that will also deepen the companies' co-operation in the development of therapies for rare genetic diseases.
- Sanofi is paying $80 a share for the stake, a 21% premium to Alnylam's closing price of $66.21 on Friday.
- Sanofi and Alnylam will expand their partnership involving Patisiran, a development-stage treatment for a rare life-threatening nervous-system disease called transthyretin-familial amyloid polyneuropathy. Sanofi will sell Patisiran in all markets outside North America and Western Europe, adding to its rights in Japan and Asia-Pacific.
- Sanofi will gain the rights to develop and market three other drugs as well, and an option on all of Alnylam's drugs for rare genetic diseases.
- The deal comes after Sanofi suffered a patent cliff in which it lost IP protection on nine drugs in three years. (PR)
Monday, Jan 133:29 AM| Comment! -
Thursday, Jan 91:18 PM
- Some more big pharma coverage from UBS has the team initiating Novartis (NVS +0.4%) with a Buy rating. Started at Neutral are GlaxoSmithKline (GSK) and Sanofi (SNY -0.5%).
- Earlier: AstraZeneca is initiated a Buy.
Thursday, Jan 91:18 PM| 1 Comment -
Wednesday, Jan 811:02 AM
- Aegis figures now is a good time to hike the price target on Oramed Pharmaceuticals (ORMP +20.1%) to $30 from $25 as "positive proof-of-concept data has been generated in animals for both ORMD-0801 [and] ORMD-0901."
- Here's analyst Ram Selvaraju, commenting: "Positive Phase 2b data [in ORMD-0801] could set the scene for a transformative licensing transaction or an acquisition by an established diabetes focused firm like AstraZeneca (AZN), Novartis (NVS), Novo Nordisk (NVO), or Sanofi (SNY)."
- The shares are up 222% since the company reported successful results with its oral insulin capsule last month.
Wednesday, Jan 811:02 AM| Comment! -
Thursday, Jan 28:06 AM
- Sanofi (SNY) says it will join the industry-wide effort to expand access to clinical trial data.
- There are some conditions. Data will only be made available if the studies "have been submitted to U.S. and E.U. regulatory agencies and the product must have been approved by both agencies on or after January 1, 2014."
- SNY does note however that it "will continue to submit for publication the results from all company-sponsored clinical studies, regardless of study outcome." (PR)
Thursday, Jan 28:06 AM| Comment! -
Monday, Dec 302013, 8:00 AM
- Genzyme (SNY) will appeal the FDA's rejection of the MS treatment Lemtrada.
- The company says it "strongly believes that the clinical development program ... provides robust evidence of efficacy and a favorable benefit-risk profile."
- SNY says the contingent value right milestone tied to U.S. approval by the end of March 2014 will be missed. (PR)
- GCVRZ -71% premarket.
- GCVRZ discussion forum on Seeking Alpha
Monday, Dec 302013, 8:00 AM| Comment! -
Monday, Dec 302013, 2:11 AM
- The FDA has rejected Sanofi's (SNY) Lemtrada treatment for multiple sclerosis, saying that the French company hasn't submitted enough evidence to show that the benefits of the drug outweigh its serious side effects.
- The decision is not a total surprise, as FDA staff had already raised safety concerns and questioned the adequacy of clinical trials.
- However, the agency did leave open the possibility that Lemtrada could eventually be approved, but Sanofi would need to conduct more testing first.
- The FDA's rejection comes despite authorization from the EU and Canada, and after the U.K.'s NICE authority asked for more information by January 9.
- Contingent value right tied to Lemtrada: GCVRZ (PR)
Monday, Dec 302013, 2:11 AM| 2 Comments -
Friday, Dec 202013, 8:47 AM
- "The market has gone straight up all year in every sector of the economy. Who owns any loser anywhere?," asks SA contributor Chris DeMuth, before answering his own question by looking in the mirror: "Alas, me!"
- DeMuth is referencing CVR's on Sanofi's (SNY) MS treatment Lemtrada, which faces an uphill battle for U.S. approval after FDA staff raised safety concerns and questioned the adequacy of clinical trials. The CVR's fell by nearly three quarters early last month when the briefing docs were released ahead of what ended up being a messy Ad Com the following week.
- Nevertheless, the CVRs ((GCVRZ)) are DeMuth's "best long idea for 2014," despite the money manager's contention that owning "such a security could be a firable offense."
- The rationale: "Add up the various foreign markets, apply conservative but reasonable premises, and compare the likely rewards with the cost of this security. It appears that the likely payments are probably a multiple of the current price."
- In related news: As of Thursday, Lemtrada is approved in Australia. For reference (and for a chuckle), see DeMuth's list of countries that have approved the drug.
Friday, Dec 202013, 8:47 AM| 2 Comments
Instablogs are blogs which are instantly set up and networked within the Seeking Alpha community. Instablog posts are not selected, edited or screened by Seeking Alpha editors, in contrast to contributors' articles.


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Re: Stewie back at practicehttp://reederstake.freedomblogging.com/2009/09/09/panthers-rb-stewart-lb-beason-return-to-practice/1293/
"This is blood for blood and by the gallon. These are the old days, the bad days, the all-or-nothing days. They're back! There's no choice left. And I'm ready for war." |
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Re: Stewie back at practiceSweet!!! If it gets here in time I will wear my Beef Stew Jersey to celebrate his return on Sunday. I do home Goodson gets some play time though. I am interested to see how he does in a real game situation. |
Administrator has disabled public posting |
Re: Stewie back at practiceBeason is back too. I hope we got all of our inj. out of the way for the year. I will be interested to see how our D-line plays against the ingles O-line. Also, our o-line is going to have one hell of a time holding against the blitz happy Eagles. |
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At Black & Spiro lately we have been concentrating on our new look which will be centred around the colours blue and pink so I thought I would show you a few blue and pink images which have been inspiring me.
Monday, 11 June 2007
Blue & Pink Inspirations
At Black & Spiro lately we have been concentrating on our new look which will be centred around the colours blue and pink so I thought I would show you a few blue and pink images which have been inspiring me.
10 comments:
- style court said...
What a beautiful mix Anna! Can't wait to see pics of the shop as is evolves. Thanks for the mention!
BTW: that India Hicks picture you've used as image of the week (the deep pink landing in her island home) is such a favorite of mine. - 11 June 2007 11:18 pm
- The Peak of Chic said...
All gorgeous images, and very inspiring too!
- 12 June 2007 12:22 am
- Daniel Sroka said...
Pink seems to be the theme this weekend! I spend the other day shooting a small pink flower my 3 year old presented to my wife after a walk in our local park.
- 12 June 2007 1:20 am
- katiedid said...
So pretty! I can hardly wait to see the shop. Love the pics, esp. the bike, gate and houses.
- 12 June 2007 2:06 am
- FrenchGardenHouse said...
Thank you for showing these amazing photographs, I love all the Blue and Pink. I am leaving your blog totally inspired!
I'm especially in love with the Stylecourt stationary...just stunning!
Lidy - 12 June 2007 2:06 am
I love how you paired photographs with fabric patterns, very inspiring.
- 12 June 2007 3:26 am
- Pacchai Milagai said...
blue and pink buildings is my favourite pic.
- 12 June 2007 5:39 am
- girl meets glamour said...
Great collection of inspiring images. Your Friday post got me thinking of my love for blue and white as well :)
- 12 June 2007 6:32 am
- TinkerBlue said...
Pink and blue are mt favourite. Love the tin of soaps.
My copy of :My French Life" arrived. The photos are stunning. Can't wait to sit and read it. - 12 June 2007 3:58 pm
- Belinda said...
WOW!!! These things really are absolutely beautiful.
Mesmerising. - 13 June 2007 12:27 pm


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We're Nest. We reinvent things.
We take the unloved products in your home and make simple, beautiful, thoughtful things.
Our people are Nest.
Our team.
We take what's familiar and look at it in a new light. Our team focuses on making technology that's simple, fresh and helpful.
Tony FadellTony Fadell
Founder & CEO
Tony led the team that created the first 18 generations of the iPod and the first three generations of the iPhone. Before Apple, Tony built the Mobile Computing Group at Philips Electronics. Tony has authored more than 300 patents. He graduated from the University of Michigan with a Bachelors in Computer Engineering.
Read Tony's blog postings -
Matt RogersMatt Rogers
Founder & Engineering
Matt was responsible for iPod software development at Apple, from concept to production. He is passionate about mobile products, loves team building and rapid productization. Matt earned his BS and MS degrees from Carnegie Mellon University.
Read Matt's blog postings -
Erik CharltonErik Charlton
Erik joined Nest from Logitech, where he was VP of Product Marketing for their core business – mice. Prior to that Erik co-founded Jarna, a wireless synchronization technology company acquired by Visto. Erik is a Stanford University graduate and earned his MM from Stanford's Graduate School of Business.
Read Erik's blog postings -
Shige HonjoShige Honjo
Program Management and Manufacturing
Shige has more than 20 years of consumer electronics design, development, and execution experience on more than a dozen mobile phones and other products. Prior to Nest, Shige was the lead engineering program manager at Apple for several early generations of iPhone from concept to ramp. He received his BS in electrical engineering from Georgia Institute of Technology.
Chip LuttonChip Lutton
General Counsel
Chip spent 10 years as Apple's associate general counsel for intellectual property, securing and protecting Apple's innovations during the iPod-iPhone-iPad decade. He's also worked at Sun Microsystems and for the current Chief Judge of the US Court of Appeals for the Federal Circuit. He has a law degree from Columbia University and a BS in electrical engineering from Rice University.
Yoky MatsuokaYoky Matsuoka
Yoky served as the Head of Innovation at Google and Professor of Computer Science and Engineering at the University of Washington before joining Nest. She graduated from UC Berkeley and earned an MS and PhD in Electrical Engineering and Computer Science from MIT. She received the MacArthur Genius Award for her work in robotics and neuroscience.
Read Yoky's blog postings -
Doug SweenyDoug Sweeny
Doug has more than 20 years of experience leading marketing for iconic, global brands like Levi's, adidas and General Motors EV1. He was VP of Global Marketing for Levi's and architect of the Go Forth campaign in which he was selected by Advertising Age as one of the Top 50 Innovative Marketers today. Doug graduated with a BS from Syracuse University.
Read Doug's blog postings -
vonReichbauerTom vonReichbauerTitle
Tom joined Nest from Tesla Motors where he was the company's Director of Finance. Prior to Tesla, Tom held several financial management roles at Ford Motor Company. He has a BS in economics and an MBA, both from the Wharton School of Business at the University of Pennsylvania.
Contact us.
Here's how you can get in touch with someone at Nest.
Find answers to common questions on our support site or ask the Nest Community.
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HVAC and home automation pros can get Nest Certification and grow their business.
If you'd like to do business with Nest, fill out this form with info about yourself and what you're looking for:
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Nest is working with energy providers across the US to help customers save.


text:
Artist: The Sound of Music
Album: Miscellaneous
Genre: Electronic
The Sound Of Music
The Sound Of Music (Maria)
The hills are alive with the sound of music
With songs they have sung for a thousand years
The hills fill my heart with the sound of music
My heart wants to sing every song it hears
My heart wants to beat like the wings of the birds
that rise from the lake to the trees
My heart wants to sigh like a chime that flies
from a church on a breeze
To laugh like a brook when it trips and falls over
stones on its way
To sing through the night like a lark who is learning to pray
I go to the hills when my heart is lonely
I know I will hear what I've heard before
My heart will be blessed with the sound of music
And I'll sing once more
i luv this song
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1 | Something Good |
2 | An Ordinary Couple |
3 | The Sound Of Music (Reprise) |
4 | Prelude and the Sound of Music |
5 | How Can Love Survive? |
6 | The Sound of Music |
1 | Cosmic LoveFlorence |
2 | Drumming SongFlorence |
3 | Eyes On MeNobuo Uematsu |
4 | Rabbit Heart (Raise It Up) H_*Florence |
5 | Dog Days Are OverFlorence |
6 | Keep The Streets Empty For MeFever Ray |
7 | HeartbreakerMSTRKRFT |
8 | We Are The PeopleEmpire Of The Sun |
9 | Half MastEmpire Of The Sun |
10 | Full MoonThe Black Ghosts |
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First aid for heavy partiersHey folks, Recently I've had two people I've known die of an accidental overdose and I had to take care of & put another person in ho… Started by Adrian Fynch |
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Online gaming has taken the entertainment market by storm. Leading the way is the explosive growth of the Massively Multiplayer Online (MMO) Games, with millions of players engaged in ongoing interactive game play.
This highly targeted audience is so immersed in their online world they have been notoriously difficult to reach through traditional forms of media -- until now.
Traffic Overview | |
Unique Visitors | 8.6 million visitors per month |
Page Views | 409.5 million page views per month |
Core Demographic | 18-49 year olds - 81% |
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text:
I was working in inDesign on my Mac this morning without a problem, then suddenly it started to give me several errors at once. When I tried to save my new file, it gave me error code: 0 and said "cannot save under a new name. The file (lots of numbers and letters) is damaged."
I tried resetting the preferences in the applications folder manually and it still doesn't work. I opened a new document to try to save a blank page (in case my file that was corrupted) and it gave me the same error message. I reset all the preferences by holding down CMD + option + contrl + shift immediately after launching indesign, and that didn't work either. I uninstalled CS5 completely, reinstalled everything, it worked for about 5 minutes and then started giving me the same problem.
The program is also not always exporting files properly, giving me an error message in background tasks when I try to save as either a PDF or downsave to IDML. I deleted the INDD file that I thought was causing all the problems but it is still happening.
I've spent all day trying to fix this and still have not found a solution that works. Any help you can provide is much appreciated! This is very frustrating.
Thank you in advance!
Hi Peter,
Turns out I figured out the problem, I was trying to save my INDD file into a folder that was "locked" by the previous owner, so no files could be added, modified, or removed from it. I guess when I tried to save my file in that locked folder the program went a little crazy, but as soon as I saved the file in a new folder that was not locked everything worked smoothly and all problems disappeared.
Have you seen this happen before? This is my best guess as to what could have gone wrong, it is the only thing that was different from my usual day-to-day routine. Everything else is automatically updated and I don't have any third party plug-ins or font managers.
I believe so, it kept telling me that the file was damaged whenever I tried to save. What was more strange was that it was doing the same thing to other files as well. But as soon as I started saving to the desktop and other folders everything stopped giving me error messages and corrupt file notifications. I then deleted the original brochure file and started a new one from scratch, since I had a feeling that was what was giving me all of the issues.
When faced with a situation like that I often recommend what is probably the scariest thing you will ever do in ID -- Pull the plug to force a crash. (Force Quit might work). The idea is that when you restart ID it will immediately open the recovery file, if it isn't damaged, and you can export that to .idml.


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Economic Trends
The Akron Metropolitan Statistical Area
The Akron metropolitan area—home to 702,000 residents—stretches across Summit and Portage Counties. The region is typical of many metro areas in the Fourth District in that it has seen limited population growth over the past three decades. In fact, since 1970 Akron's population grew by only 3.5 percent compared to 46 percent for the United States.
Source: U.S. Department of Commerce, Bureau of the Census.
Although Akron enjoys a relatively diverse economy, the manufacturing sector still claims the highest employment concentration relative to the United States, followed by professional and business services.
Location Quotients, 2005, Akron MSA / U.S.
Note: The location quotient is the simple ratio between two locations of a given industry's employment share
Source: U.S. Department of Labor, Bureau of Labor Statistics.
Nevertheless, manufacturing employment in the Akron region has experienced a dramatic decline since the last business cycle peak in March 2001—17.4 percent compared to a 16.3 percent decrease for the United States. In contrast, Akron outpaced the country as a whole in non-manufacturing job growth during the same time period—8.4 percent locally versus 5.3 percent nationally.
Payroll Employment Since March 2001
Source: U.S. Department of Labor, Bureau of Labor Statistics.
Looking more closely at total annual employment growth, we see that the United States did slightly better than the Akron metro area in 2001 and 2002. This was due primarily to a larger decline in local manufacturing jobs. However, beginning in 2003 and continuing through 2005 the trend was reversed. During this latter period Akron showed annual employment gains of 1.5 to 2.0 percent. Further, manufacturing job losses became negligible and increases were seen in two broad sectors—finance, information and business services and education, health, leisure, government and other services.
Components of Employment Growth Akron MSA
Note: The white bars represent total annual growth for the Akron MSA. The blue line is U.S. growth.
Source: U.S. Department of Labor, Bureau of Labor Statistics.
Local employment trends seen during 2003 through 2005 continued into 2006. For the 12-month period ending in October, financial activities, information, and professional and business services led all other industry sectors in employment growth with increases ranging from 2.3 to 4 percent. Manufacturing continued to show a negligible employment change on a year-over-year basis.
Payroll Employment Growth, October 2006
Source: U.S. Department of Labor, Bureau of Labor Statistics.
During the 1990s, the Akron metro area enjoyed a consistently lower unemployment rate than the United States. In fact, during the mid 1990s, local unemployment was about one percentage point less than was reported nationally. Only during the past three years has this trend been reversed. For the 12-month period ending in October 2006, Akron's average unemployment rate was 0.5 percentage point higher than in the United States.
Unemployment Rate
Source: U.S. Department of Labor, Bureau of Labor Statistics.
Over time, average per capita personal income across all U.S. metro areas has been somewhat higher than in Akron with a gap of about 6.4 percent. However, when comparing per capita income growth, we find that the growth rates in Akron and the United States are almost the same. Between 1980 and 2004, local income increased by 219 percent compared to 226 percent nationally.
Per Capita Personal Income
Source: U.S. Department of Commerce, Bureau of Economic Analysis.
The similarity in growth may be partially due to the educational attainment of Akron residents. In 2005, over 28 percent of these residents held a bachelor's degree or higher. This compares to 23.3 percent in Ohio and 27.2 percent nationally.
Selected Demographics
Akron MSA | Ohio | U.S. | |||
Total population (millions) | 0.7 | 11.2 | 288.4 | ||
Percent by race | |||||
White | 86.1 | 85.7 | 76.3 | ||
Black | 12.2 | 12.3 | 12.8 | ||
Other | 1.7 | 2.0 | 10.9 | ||
Percent by age | |||||
0 to 19 | 26.0 | 27.0 | 27.8 | ||
20 to 34 | 19.3 | 19.3 | 20.1 | ||
35 to 64 | 41.6 | 40.8 | 40.0 | ||
65 or older | 13.0 | 12.8 | 12.1 | ||
Percent with a bachelor's degree or higher | 28.1 | 23.3 | 27.2 | ||
Median age | 38.3 | 37.6 | 36.4 |
Source: U.S. Department of Commerce, Bureau of the Census.


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Hey ladies. I'm 28 yrs old and seriously thinking about getting botox. I have read some reviews about the crows on your forehead. And yes I have about 3 lines which you can see when I frown. I also have 2 lines in between my eye also. The bad part about all this is most of the time I'm frowning and don't even realize it. And at times I frown so much it makes the spot between my eyes hurt. And when I say hurt I don't mean like a headache, it's more like my muscle get tight and stiff. So when that happens I have to get a hot towel and lay it on my forehead and my eyes. The hott towel actually relax my muscle it allows the pain to stop.
So my question to you ladies who already have more experiance in this then I do: am I to young for Botox or would botox help with the tightness of my muscle in my forehead and crow lines??? Also I live in Miami fl, so which Docter would be great to go to???? Any advice would be greatful
I Need Your Help Ladies. 28 Yr Old Female. Not Sure What to Do - Miami, FL
Hey ladies. I'm 28 yrs old and seriously thinking...
Comments (4)
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From what you are describing it sounds to me like Botox might be a good thing to consider. Since you have a somewhat unusual thing going on with the pain between your eyes I would definitely recommend you talk to a doctor about that specific concern and whether or not Botox is the right approach.
To help find a doctor you can click on the Doctor Finder tab near the top of the page. You can search in your area, the further narrow the results by either procedure or specialty. That will give you a list of doctors that you can read the profiles of, read other reviews about them, and see what questions they have answered in the Q&A section. Hopefully that will give you an idea of if they are someone you want to consider going to for treatment.
Looking forward to hearing what you decide to do!
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His story has been well told: Dr. Alfredo Quiñones-Hinojosa ("Dr. Q" to friends) was an illegal immigrant from Mexico who put himself through medical school—at Harvard, no less—and now is a top neurosurgeon at Johns Hopkins. Below, he tackles a slightly lesser challenge: The Baltimore Grill.
Where did you go to school?
I started my education in a small rural school in a quiet, peaceful little farming community surrounded by the dessert of Baja California on the outskirts of Mexicali, Mexico. Mexicali was looked upon as a "big town" by the people I grew up with and I eventually went there to study to become an elementary school teacher. I continued my schooling in the United States, learning English at San Joaquin Delta College in northern California and finishing my bachelors at UC Berkley. I went on to medical school at Harvard and returned to California to do my residency in neurosurgery at the University of California, San Francisco.
What book or films most changed your life?
I remember reading the book by Gabriel Garcia Marquez Love in the Time of Cholera—what an amazing story. This great work by the gifted Colombian-born Nobel Prize winner taught me two very important lessons—keep your dreams alive and no matter what happens, if you give the world your best, the best will come back to you.
One of the films that had a great impact on my life was the 1976 movie Rocky. Interestingly I didn't get a chance to see this movie until I came to the United States in the mid 80's. As you can imagine, I could really relate a lot to the story—the idea of realizing the "American Dream" and the idea of giving your best in any given situation were important messages that I also felt deep in my heart. Both Rocky and I had to "go the distance" to realize our dreams. I have always believed that it is not only what we have in our brains but it is also what we carry in our hearts that allows us to achieve great things.
Who is your favorite Baltimorean?
Wow this is a tough question! How can one have one favorite? I have several favorites to be honest with you. A group that is extremely important to me and also part of my life are my patients—many of whom are from Baltimore. I often form close relationships with my patients—what can be closer than operating on someone's brain? Through my relationships with my patients, I learn a lot about them, their families and myself. Finally, I am inspired by the students and post-doctoral fellows working in my laboratory. They work very hard helping find better ways to cure brain cancer. My team reminds me of what Santiago Ramon Y Cajal (Nobel Prize Winner in 1906) said once: "Science like an army needs generals and needs soldiers; the former may do the thinking but it is the latter who do the conquering!"
What is the best advice you ever got?
The best advice I ever got was to bet on myself, be humble, be a good human being and never forget where I came from—my roots! My parents taught me early in my life to treat others the way I would like my loved ones to be treated.
What is the biggest mistake you have ever made?
I have made a lot of mistakes in my life. But it is not the errors and mistakes that matter most, it's how we respond to those errors and mistakes that makes the difference.
What is the bravest thing that you have ever done?
I was told as a little boy that familiarity with danger makes a brave person braver. I think that without question dealing with my patients with brain cancer in and out of the operating room is the bravest thing I do every day.
What is the greatest problem facing Baltimore today?
I think the greatest problem we face in Baltimore is education. We need to educate our people; we need to educate our future generations of students that are going to carry us forward. Our future scientists, artists, and writers could be among those kids that are struggling on the streets of our wonderful city. We need to go back to what made this country a beautiful nation, hard work and education. We need to try to help this nation's young people get ahead in life.
When were you most tempted to leave Baltimore?
I can say that I have never been tempted to leave Baltimore. I am very happy where I am today. Baltimore is a wonderful city with a wonderful multicultural and diverse society. I feel at home here everyday.
Who would play you in the movie for your life?
Honestly, it is hard to imagine someone would want to make a movie about me, so I haven't much thought of who I would choose to play me if such a movie was made. But I do think very highly of Javier Bardem after his performance in the movie No Country for Old Men. Javier I think would do a phenomenal job not so much because of me or my story but because of my respect for him as an artist.
What is your guilty pleasure?
I love sweets, I can not deny it. I think that it runs in my blood.
If you could write Baltimore's motto what would it be?
Strive for Perfection and Never Give Up!
There are so many illegal immigrants working below their true abilities what advice would you give them?
Never work below your true abilities. Always keep moving forward. No matter what you do, whether you sweep the floors, whether you shovel fish deposits in a tank, whether you are a scientist or a carpenter, always give it your best the best will come back to you. Even if you are doing the most menial job, do it to the best of your ability and this country and its citizens will recognize your talent.
You have no doubt inspired others to strive for greatness. Has anyone told you a specific story of your influence?
So many great people have had an incredible impact on my life. I have almost lost count. And I too have had the privilege of passing down the advice that has been given to me over the years. Some of my students have thanked me profusely for having changed their lives and given them the opportunity to realize their potential. Once when I was a resident and it had been a very long night in the hospital, I had a medical student sitting with me and I asked him what he wanted to do with his career. For many years he had thought about becoming a brain surgeon but he told me that he didn't think he had what it takes. I had worked with the students already for a few months and I just knew that he could make it. I looked at him in the eyes and said that you have everything that it takes and more. The question is do you want to do it? Yes or no? He eventually graduated from brains surgery residency at the University of California. When we spoke again a few years later, he told me how much of an impact that moment had in his life and how it really made him realize that he could fulfill his dreams as a brain surgeon. I was just happy that I had the opportunity to play a small part in helping him with his life.
You seem very humble about neurosurgery. You see it almost as a craft, right?
Neurosurgery is very complicated in the sense that we understand so little about this beautiful organ known as the brain. Remember this is the organ that allows us to be who we are, that allows me to do brain surgery. My biggest challenge is to try to simplify this very complex organ so we can better understand how it works, and what is happening when it doesn't work the way it was supposed to. I am humble about neurosurgery because I think and realize everyday that is spite of how much we know and continue to learn about the brain, we are still in the embryonic stages of understanding this wonderful organ. I am also humbled by the courage my patients have and the trust they have in me when they place themselves in my care.
One slip is the difference between life and death. How do you handle that pressure? Do you allow yourself to think about it?
It is true that neurosurgery is a game of life and death and it is a profession that requires a great amount of concentration and dedication and focus. A fair amount of pressure comes when you are in the operating room. I think the way I deal with is by becoming part of the patient, by fully connecting with the patient in the operating room, by feeling I am part of their body. This puts me in a state of deep concentration and focus. Many people wonder whether or not surgeons are afraid and I always say that it is not fear that matters, it is how we gather that energy that fear brings. Fear is a product of the realization that you are faced with a big challenge. If this energy is properly channeled, it can help your senses become hyper acute, become fully aware of everything. It can also help you find peace in the operating room. Your hands, your pulse, your body are at peace and nothing can startle you, yet you have the ability to react in a fraction of a millisecond to a difficult situation that can mean the difference between life and death. It is that tension and the resulting concentration that allows you to do this wonderful job and allows you to be fully connected and fully aware and ready to respond to anything that might come.
How do you avoid getting that "God complex" that surgeons are often accused of having?
Brain surgery is what I was trained to do, my hands, my skill, my knowledge are part of a large system that includes neurologists, nurses, technicians, administrators and much more. In addition, I am humbled everyday by my own patients, by seeing them struggle through a difficult disease, through a difficult post operative care. When you really connect with your patients, if you can feel their pain and share their emotions and experiences, you realize we are all in this together and we are all equal in our own way.
You seem like a very happy guy, have you always been that way and does it help in your work?
I have always been this way, I love what I do, I have always loved every single thing that I have done, all the way from when I was just a little kid working at the gas station to growing up selling corn and hot dogs on the corner, to coming to the United States as an immigrant farm laborer. I love my life now as a brain surgeon. I enjoy every single moment, every breath I take I consider it a gift—a major privilege. I think that our attitudes and the way we see the world will have an effect on the way the world perceives us. I always try to focus on the positive, no matter how difficult the times may be and that helps me achieve a balance that allows me to be happy and to smile in the midst of chaos, in the midst of disaster, in the midst of difficult situations. To try to remain at peace with yourself, with both your strengths and your weaknesses, is really one of the greatest challenges that we face as human beings.
What is your greatest success as a brain surgeon?
I think my greatest success as a brain surgeon has been seeing my patients and their families experience joy and happiness after I have performed surgery on them or one of their loved ones. When I see them smile in my clinic or after surgery, and thank me and hug me, I know that what matters most is that my patients can have a good quality life after coming to see me. That for me is my greatest accomplishment. If, in addition, I can contribute to the group of people that are working to find a cure for brain cancer then I will also consider that a great success. Every single one of my patients and their loved ones deserve our commitment to curing brain cancer since they are the ones that struggle everyday fighting their disease.
What is the greatest disappointment?
The fact we are continuing to do a lot of work on the human brain and yet we still know so little about it. Every time one of my patients succumbs to a fatal neurological disease such as brain cancer, I feel pain and frustration for the patient and their family and for the fact that medical science has not progressed to the point where we can slow down diseases like brains cancer.
What's a Dr. Q operating room like? Quiet and intense? Relaxed? Is there music?
I like to think of my operating room as an extension of my laboratory. It is intense when it needs to be intense, it is relaxed when it can be relaxed. We have music when the situation allows for it.
What is one operating anecdote that your patients probably got that they didn't know?
I don't have anecdotes that I don't tell my patients. I believe in honesty and openness and in the operating room there is no room for mistakes. Every significant event happens in the operating room is shared with my patients and their families. There are no secrets.
If you weren't a brain surgeon what would you like to do?
I think that one of the noblest professions in our society is teaching. Teachers are and extension of the family, they are the backbone of society. Without teachers and education, we wouldn't have medicine, literature, science, industry, art, music . . . in essence, the world as we know it, would very likely not exist.


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Quick Facts
- NAME: Steve Earle
- OCCUPATION: Anti-War Activist, Songwriter, Guitarist, Singer
- BIRTH DATE: January 17, 1955 (Age: 59)
- PLACE OF BIRTH: Fort Monroe, Virginia
- Full Name: Stephen Fain Earle
- AKA: Steve Earle
- ZODIAC SIGN: Capricorn
Best Known For
Steve Earle is a Grammy Award-winning singer-songwriter whose albums seamlessly blend rock, folk and country. He has also appeared on the HBO series The Wire and Treme.
Think you know about Biography?
Answer questions and see how you rank against other players.
Play NowSteve Earle. (2014). The Biography Channel website. Retrieved 02:19, Mar 11, 2014, from http://www.biography.com/people/steve-earle-507625.
Steve Earle. [Internet]. 2014. The Biography Channel website. Available from: http://www.biography.com/people/steve-earle-507625 [Accessed 11 Mar 2014].
"Steve Earle." 2014. The Biography Channel website. Mar 11 2014, 02:19 http://www.biography.com/people/steve-earle-507625.
"Steve Earle," The Biography Channel website, 2014, http://www.biography.com/people/steve-earle-507625 [accessed Mar 11, 2014].
"Steve Earle," The Biography Channel website, http://www.biography.com/people/steve-earle-507625 (accessed Mar 11, 2014).
Steve Earle [Internet]. The Biography Channel website; 2014 [cited 2014 Mar 11] Available from: http://www.biography.com/people/steve-earle-507625.
Steve Earle, http://www.biography.com/people/steve-earle-507625 (last visited Mar 11, 2014).
Steve Earle. The Biography Channel website. 2014. Available at: http://www.biography.com/people/steve-earle-507625. Accessed Mar 11, 2014.
Steve Earle was born on January 17, 1955 in Fort Monroe, Virginia and grew up in Texas. Following the example of his musical hero Townes Van Zandt, Earle became a folk and country singer-songwriter. His debut studio album was Guitar Town in 1986. Drug and personal problems derailed Earle's career in the late 1980s,
but he eventually returned to recording and has since won multiple Grammys. Television fans will recognize Earle from his roles on the HBO's The Wire and Treme.
Early Life
Stephen Fain Earle, better known as Steve Earle, was born in Fort Monroe, Virginia on January 17, 1955, and grew up in Texas. Influenced at a young age by legendary folk-rock musicians Townes Van Zandt, Guy Clark and Woody Guthrie, Earle became a skilled guitar player by the age of 13.
Musical Career
In 1975, a 20-year-old Earle traveled to Nashville, Tennessee to embark on a musical career, and soon met with childhood inspirations Guy Clark and Townes Van Zandt. When Earle began performing at small Nashville venues, country fans were initially put off by his long hair and opposition to the Vietnam War. His strong musical abilities and unique country-rock style, however, eventually won out.
Earle's debut studio album, 1986's Guitar Town, met with both commercial and critical acclaim, with one track, "Goodbye's All We Got Left," landing on the country music chart's Top 10. Two years after releasing Guitar Town, Earle completed his second album, Copperhead Road (1988), which also received wide applause. In 1990, following several failed relationships and battles with addiction, he released The Hard Way, an emotional and somewhat darker project than his prior two releases.
Earle incorporated his politically left ideals—including his anti-death penalty and -war stances—into several songs on the albums Jerusalem and The Revolution Starts...Now, released in 2002 and 2004, respectively. For Revolution, Earle won a Grammy Award (for best contemporary folk album). Four years later, he won another Grammy (for best contemporary folk/Americana album) for 2008's Washington Square Serenade, which features a song performed by Earle and his sixth wife, Allison Moorer. He received a third Grammy (for best contemporary folk album) in 2009, for his Townes Van Zandt-tribute album, Townes.
Recent Projects
In 2011, Earle released a folk-rock project that he titled after a Hank Williams song, Never Get out of This World Alive. In July 2012, Earle hosted an event called Woodyfest, in celebration of Woody Guthrie's 100th birthday, in New York City. The event included performances by Earle, along with Tim Robbins, John Hammond, Billy Bragg and Amy Helm, among others.
Today, Steve Earle is regarded for successfully bridging the rock-country music gap, blending the two genres to create a new, beautifully unique style that few musicians have been able to replicate.
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Included In These Groups
Folk Singers and Folk Revolutionaries
With simply their voices and guitars, folk singers are the unplugged artists who tell our collective stories through their songs. Their music conveys universal truths and, in turbulent times, is often a call to action in the form of protest songs. Woody Guthrie, Bob Dylan, Joan Baez and other legendary folk singers have rallied audiences around historic causes such as the Civil Rights, peace and feminist movements. Here are some of the famous folk singers who were revolutionary through their songs.
Folk Singers and Folk Revolutionaries 30 people in this group
Famous Capricorns 524 people in this group
Famous Antiwar Activists
Browse notable antiwar activists such as Queen Rania, Coretta Scott King, and Jane Fonda.
Famous Antiwar Activists 48 people in this group


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Cutting & Other Forms of Self-Injury: Why Kids Hurt ThemselvesDenise SchiraFriday, May 31, 2013 from 8:30 AM to 1:00 PM (EDT)Bronx, NY |
Who's Going
Event Details
Cutting and Other Forms of Self-Injury: Why Kids Hurt Themselves and How You Can Help
Learning goals:
- Participants will learn how to recognize self-injury
- Participants will understand the link between self-injury and overwhelming emotions
- Participants will learn how to talk to children and families about self-injury
- Participants will discuss the role of school personnel in helping children and teens who self-injure.
- Participants will learn where children and families can receive help for self-injury
Trainers: Shirley de Peña, LCSW & Mary Dino, LCSW
Audience: Guidance Counselors, Social Workers, Special Education Liaisons, Psychologists, Assistant Principals, Family Workers, Deans, Parent Coordinators, Network Youth Development and Family Engagement Point Persons
CEI-PEA Schools and Networks are invited. A light breakfast will be provided.
When & Where
1230 Zerega Avenue
Friday, May 31, 2013 from 8:30 AM to 1:00 PM (EDT)
Add to my calendar
Denise Schira
Denise Schira
Deputy Network Leader
Director Student Services
CEI-PEA Children First Network 534
NYC Department of Education
1230 Zerega Ave, Suite 43
Bronx, New York 10462
Office: 718-828-2762
Blackberry: 917-207-0695
Fax: 718-828-3700
Email: email@example.com


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- Musician's Friend Best Selection, Price & Service. Guaranteed.
Need Help? Ask our Experts or call 800-449-9128
Private Reserve Guitars 866-926-1923
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Our product catalog varies by country due to manufacturer restrictions. If you change the Ship-To country, some or all of the items in your cart may not ship to the new destination.


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Update: Riverside hospital to restore open-heart surgery late Friday
| Apr 16, 2010
NEWPORT NEWS — The ability to conduct open-heart surgery will be restored as of 7 p.m. Friday, a Riverside Health System spokesman said.
Riverside has been recruiting an anesthesiologist for Riverside Tappahannock Hospital. The candidate they hired...


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A fourth suspect has admitted his involvement in the shooting death of U.S. Border Patrol Agent Robert Rosas. Our television partner KYMATV says 28 year old Marcos Rodriguez-Perez entered a guilty plea in a federal court Wednesday in connection to the 2009 murder of Agent Rosas.
Rodriguez-Perez admitted he was one of three gunmen who lured him into a trap to steal his night-vision goggles and then fatally shooting him during a struggle. Rodríguez-Perez pled guilty to conspiracy to commit robbery and kidnapping, robbery of personal property of the United States and use and carrying of a firearm during the commission of a crime of violence.
He was sentenced to 58 years in prison.


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- About this Journal
- Abstracting and Indexing
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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 792793, 2 pages
Neuroendocrine Mechanisms of Acupuncture
1Acupuncture and Moxibustion Institute, College of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430061, China
2Department of Integrated Traditional Chinese Medicine and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
3Laboratory of Comparative Neuroimmunology, Department of Neurobiology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA 90095-1763, USA
Received 2 May 2012; Accepted 2 May 2012
Copyright © 2012 Fengxia Liang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
How to Cite this Article
Fengxia Liang, Rui Chen, and Edwin L. Cooper, "Neuroendocrine Mechanisms of Acupuncture," Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 792793, 2 pages, 2012. doi:10.1155/2012/792793