text:
Systematic (IUPAC) name | |
(4bS,8aR,9S)-3-methoxy-11-methyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene | |
Clinical data | |
Trade names | Robitussin, Delsym, DM, DexAlone, Duract |
AHFS/Drugs.com | monograph |
MedlinePlus | a682492 |
Pregnancy cat. | A (AU) C (US) |
Legal status | Pharmacy Only (S2) (AU) OTC (CA) OTC (UK) OTC (US) |
Dependence liability | Low |
Routes | Oral |
Pharmacokinetic data | |
Bioavailability | 11%[1] |
Metabolism | Hepatic (liver) enzymes: major CYP2D6, minor CYP3A4, and minor CYP3A5 |
Half-life | 3-5 hours |
Excretion | Renal |
Identifiers | |
CAS number | 125-71-3 |
ATC code | R05DA09 |
PubChem | CID 15978238 |
DrugBank | DB00514 |
ChemSpider | 13109865 |
ChEMBL | CHEMBL52440 |
Chemical data | |
Formula | C18H25NO |
Mol. mass | 271.40 g/mol |
Physical data | |
Melt. point | 111 °C (232 °F) |
(what is this?) (verify) |
Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. It is one of the active ingredients in many over-the-counter cold and cough medicines, including generic labels and store brands, Benylin DM, Mucinex DM, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, TheraFlu, and others. Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.[2]
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor[3] and a sigma-1 receptor agonist.[4][5] The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist. In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic such as ketamine and phencyclidine.[6] As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.[7]
Medical use[edit]
The primary use of dextromethorphan is as a cough suppressant, for the temporary relief of cough caused by minor throat and bronchial irritation (such as commonly accompanies the flu and common cold), as well as those resulting from inhaled particle irritants.[citation needed]
A 2004 study showed that dextromethorphan was no more effective for children than a placebo.[8] Studies conducted by the American Academy of Pediatrics show that dextromethorphan is not superior to a placebo in providing nocturnal symptom relief for children with cough and sleep difficulty due to upper respiratory infections.[9]
A combination of dextromethorphan and quinidine, a CYP2D6 inhibitor, has been shown to alleviate symptoms of easy laughing and crying (pseudobulbar affect) in patients with amyotrophic lateral sclerosis and multiple sclerosis.[10] Dextromethorphan is also being investigated as a possible treatment for neuropathic pain and pain associated with fibromyalgia.[11] In 2010, the FDA approved the combination product dextromethorphan/quinidine (Nuedexta) for the treatment of pseudobulbar affect (PBA).
Dextromethorphan has been shown to be effective in treating opioid withdrawal. At doses of 2mg/kg in rats all signs of opioid withdrawal were eliminated.[12]
Recreational use[edit]
Over-the-counter preparations containing dextromethorphan have been used in manners inconsistent with their labeling, often as a recreational drug.[13] At doses much higher than medically recommended, dextromethorphan is classified as a dissociative hallucinogen, possessing certain effects that are somewhat similar to the dissociative agents ketamine and phencyclidine. It may produce distortions of the visual field - feelings of dissociation, distorted bodily perception, and excitement, as well as a loss of sense of time. Some users report stimulant-like euphoria, particularly in response to music. Dextromethorphan usually provides its recreational effects in a non-linear fashion, so that they are experienced in significantly varied stages. These stages are commonly referred to as "plateaus".[14][15][16]
Adverse effects[edit]
Side-effects of dextromethorphan use can include:[17]
At normal doses:
- body rash/itching (see below)
- nausea
- drowsiness
- dizziness
- Closed-eye hallucination
- Difficulty breathing
At dosages 12.5 to 75 times the recommended therapeutic dose:[medical citation needed]
- hallucinations
- dissociation
- vomiting
- blurred vision and/or double vision
- bloodshot eyes
- dilated pupils
- sweating
- fever
- bruxia
- hypotension
- hypertension
- tachycardia
- shallow respiration
- diarrhea
- urinary retention
- muscle spasms
- Sedation
- euphoria
- Paresthesia
- blackouts
- sight loss
- inability to focus eyes
- skin rash
Dextromethorphan can also cause other gastrointestinal disturbances. Dextromethorphan had been thought to cause Olney's Lesions when administered intravenously; however, this was later proven inconclusive, due to lack of research on humans. Tests were performed on rats, giving them 50 mg and up every day up to a month. Neurotoxic changes, including vacuolation, have been observed in posterior cingulate and retrosplenial cortices of rats administered other NMDA antagonists such as PCP, but not with dextromethorphan.[18][19] In many documented cases, dextromethorphan has produced psychological dependence in people who used it recreationally. However, it does not produce physical addiction, according to the WHO Committee on Drug Dependence.[20]
Because dextromethorphan can trigger a histamine release (allergic reaction), atopic children, who are especially susceptible to allergic reactions, should be administered dextromethorphan only if absolutely necessary, and only under the strict supervision of a healthcare professional.[17]
Drug interactions[edit]
Dextromethorphan should not be taken with monoamine oxidase inhibitors (MAOIs)[17] due to the potential for serotonin syndrome, which is a potentially life-threatening condition that can occur rapidly, due to a buildup of an excessive amount of serotonin in the body. Dextromethorphan can also cause serotonin syndrome when used with SSRI medicines, an interaction which has been documented in clinical cases where dextromethorphan is taken at recreational doses. It has been suggested that the link between therapeutic dosages of dextromethorphan and serotonin syndrome is less conclusive.[21]
Food interactions[edit]
Caution should be exercised when taking dextromethorphan when drinking grapefruit juice or eating grapefruits, as compounds in grapefruit affect a number of drugs, including dextromethorphan, through the inhibition of the cytochrome p450 system in the liver and can lead to excessive accumulation and prolonged effects. It is generally recommended that grapefruits and grapefruit juices (especially white grapefruit juice, but also including other citrus fruits such as bergamot and lime, as well as a number of non-citrus fruits[22]) be avoided while using dextromethorphan and numerous other medications.
Lab testing[edit]
Testing for this drug is done either by blood or by urine. Blood can be either serum or plasma, serum in a plain red top 2mL preferred. Urine requires only 2mL minimum.
Dextromethorphan is the dextrorotatory enantiomer of levomethorphan, which is the methyl ether of levorphanol, both opioid analgesics. It is named according to IUPAC rules as (+)-3-methoxy-17-methyl-9α,13α,14α-morphinan. As the pure free base, dextromethorphan occurs as an odorless, white to slightly yellow crystalline powder. It is freely soluble in chloroform and insoluble in water. Dextromethorphan is commonly available as the monohydrated hydrobromide salt, however some newer extended-release formulations contain dextromethorphan bound to an ion exchange resin based on polystyrene sulfonic acid. Dextromethorphan's specific rotation in water is +27.6° (20 °C, Sodium D-line).[citation needed]
Dextromethorphan has been shown to possess the following properties, mainly in binding assays to various receptors of animal tissues. Low Ki values mean strong binding or high affinity; high Ki values mean weak binding to the target or low affinity:
- Uncompetitive NMDA receptor (PCP site) antagonist (Ki = 7,253 nM).[23][24][25][26]
- σ1 and σ2 sigma receptor agonist (Ki = 205 nM and 11,060 nM, respectively). In a comparative investigation of dimemorfan, dextromethorphan and dextrorphan in mouse cells, dextromethorpan binds with relatively high affinity to Sigma-1 receptors and with very low affinity to Sigma-2 receptors.[23]
- α3β4-, α4β2-, and α7-nACh receptor (Ki = in the μM range) antagonist. Dextromethorphan binds to nicotinic receptors in frog eggs (Xenopus oocytes), human embryonic kidney cells and mouse tissue. It inhibits the antinociceptive (pain killing) action of nicotine in the tail-flick test in mice, where mouse tails are exposed to heat, which makes the mouse flick its tail if it feels pain.[27][28][29]
- μ-, δ-, and κ-opioid receptor agonist (Ki = 1,280 nM, 11,500 nM, and 7,000 nM, respectively).[30]
- SERT and NET inhibitor (Ki = 23 nM and 240 nM, respectively).[31][30][32][33]
- NADPH oxidase inhibitor.[34]
Its affinities for some of the sites listed are relatively very low and are probably insignificant, such as binding to NMDA receptors and opioid receptors, even at high recreational doses.[citation needed] Instead of acting as a direct antagonist of the NMDA receptor itself, it is likely that dextromethorphan functions as a prodrug to its nearly 10-fold more potent metabolite dextrorphan, and this is the true mediator of its dissociative effects.[23] It is not entirely clear what role, if any, (+)-3-methoxymorphinan, dextromethorphan's other major metabolite, plays in its effects.[35]
Following oral administration, dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood–brain barrier.[citation needed]
At therapeutic doses, dextromethorphan acts centrally (meaning that it acts on the brain) as opposed to locally (on the respiratory tract). It elevates the threshold for coughing, without inhibiting ciliary activity. Dextromethorphan is rapidly absorbed from the gastrointestinal tract and converted into the active metabolite dextrorphan in the liver by the cytochrome P450 enzyme CYP2D6. The average dosage necessary for effective antitussive therapy is between 10 mg and 45 mg, depending on the individual. The International Society for the Study of Cough recommend "an adequate first dose of medication is 60 mg in the adult and repeat dosing should be infrequent rather than the qds recommended."[36]
The duration of action after oral administration is approximately three to eight hours for dextromethorphan-hydrobromide, and ten to twelve hours for dextromethorphan-polistirex. Approximately 1 in 10 of the caucasian population has little or no CYP2D6 enzyme activity leading to long lived high drug levels.[37]
Because administration of dextromethorphan can trigger a histamine release (an allergic reaction), its use in atopic children is very limited.[17]
The first-pass through the hepatic portal vein results in some of the drug's being metabolized by O-demethylation into an active metabolite of dextromethorphan called dextrorphan (DXO). DXO is the 3-hydroxy derivative of dextromethorphan. The therapeutic activity of dextromethorphan is believed to be caused by both the drug and this metabolite. Dextromethorphan also undergoes N-demethylation (to 3-methoxymorphinan or MEM),[38] and partial conjugation with glucuronic acid and sulfate ions. Hours after dextromethorphan therapy, (in humans) the metabolites (+)-3-hydroxy-N-methylmorphinan, (+)-3-morphinan, and traces of the unchanged drug are detectable in the urine.[17]
A major metabolic catalyst involved is the cytochrome P450 enzyme known as 2D6, or CYP2D6. A significant portion of the population has a functional deficiency in this enzyme and are known as poor CYP2D6 metabolizers. O-demethylation of DXM to DXO contributes to 100% of the DXO formed during DXM metabolism.[38] As CYP2D6 is a major metabolic pathway in the inactivation of dextromethorphan, the duration of action and effects of dextromethorphan can be increased by as much as three times in such poor metabolizers.[39] In one study on 252 Americans, 84.3% were found to be "fast" (extensive) metabolizers, 6.8% to be "intermediate" metabolizers, and 8.8% were "slow" metabolizers of DXM.[40] There are a number of known alleles for CYP2D6, including several completely inactive variants. The distribution of alleles is uneven amongst ethnic groups; see also CYP2D6 - Ethnic factors in variability.
A large number of medications are potent inhibitors of CYP2D6. Some types of medications known to inhibit CYP2D6 include certain SSRI and tricyclic antidepressants, some antipsychotics, and the commonly-available antihistamine diphenhydramine. There exists, therefore, the potential of interactions between dextromethorphan and medications that inhibit this enzyme, particularly in slow metabolizers.[citation needed] See also CYP2D6 - Ligands.
DXM is also metabolized by CYP3A4. N-demethylation is primarily accomplished by CYP3A4, contributing to at least 90% of the MEM formed as a primary metabolite of DXM.[38]
A number of other CYP enzymes are implicated as minor pathways of DXM metabolism. CYP2B6 is actually more effective than CYP3A4 at N-demethylation of DXM, but, since the average individual has a much lower CYP2B6 content in his/her liver relative to CYP3A4, most N-demethylation of DXM is catalyzed by CYP3A4.[38]
Dextromethorphan was identified as one of three compounds tested as part of US Navy and CIA-funded research that sought a "nonaddictive substitute for codeine"; it is implied that the compound was first found to have clinical potential in this study.[41] It was first patented in 1949.[42] The U.S. Food and Drug Administration (FDA) approved dextromethorphan as a prescription antitussive drug on September 24, 1954, and subsequently as an over-the-counter cough suppressant in 1958. This filled the need for a cough suppressant lacking the sedative side-effects, stronger potential for misuse, and physically addictive properties of codeine phosphate, the most widely used cough medication at the time.[13]
During the 1960s and 1970s, dextromethorphan became available in an over-the-counter tablet form by the brand name Romilar. In 1973, Romilar was taken off the shelves after a burst in sales because of frequent misuse, and was replaced by cough syrup in an attempt to cut down on abuse[13] As of January 1, 2012, dextromethorphan is prohibited for sale to minors in the state of California, except with a doctor's prescription.[43]
See also[edit]
Wikimedia Commons has media related to Dextromethorphan. |
- Antitussive
- Cough syrup
- Hallucinogen
- Dissociatives
- Morphinans
- (+)-Naloxone - another dextrorotatory enantiomer of an opioid drug with useful non-opioid effects
- ^ Kukanich, B.; Papich, M. G. (2004). "Plasma profile and pharmacokinetics of dextromethorphan after intravenous and oral administration in healthy dogs". Journal of Veterinary Pharmacology and Therapeutics 27 (5): 337–41. doi:10.1111/j.1365-2885.2004.00608.x. PMID 15500572.
- ^ "Reference Tables: Description and Solubility - D". Retrieved 2011-05-06.
- ^ Schwartz AR, Pizon AF, Brooks DE (September 2008). "Dextromethorphan-induced serotonin syndrome". Clinical Toxicology (Philadelphia, Pa.) 46 (8): 771–3. PMID 19238739.
- ^ Shin EJ, Nah SY, Chae JS, Bing G, Shin SW, Yen TP, Baek IH, Kim WK, Maurice T, Nabeshima T, Kim HC (May 2007). "Dextromethorphan attenuates trimethyltin-induced neurotoxicity via sigma1 receptor activation in rats". Neurochemistry International 50 (6): 791–9. doi:10.1016/j.neuint.2007.01.008. PMID 17386960. Retrieved 2011-05-06.
- ^ Shin EJ, Nah SY, Kim WK, Ko KH, Jhoo WK, Lim YK, Cha JY, Chen CF, Kim HC (April 2005). "The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan". British Journal of Pharmacology 144 (7): 908–18. doi:10.1038/sj.bjp.0705998. PMC 1576070. PMID 15723099. Retrieved 2011-05-06.
- ^ "Dextromethorphan". Drugs and Chemicals of Concern. Drug Enforcement Administration. August 2010.
- ^ Hou, C; Tzeng, J; Chen, Y; Lin, C; Lin, M; Tu, C; Wang, J (2006). "Dextromethorphan, 3-methoxymorphinan, and dextrorphan have local anesthetic effect on sciatic nerve blockade in rats". European Journal of Pharmacology 544 (1-3): 10–6. doi:10.1016/j.ejphar.2006.06.013. PMID 16844109.
- ^ "Kids' cough medicine no better than placebo" San Francisco Chronicle, July 8, 2004
- ^ Paul, I. M.; Yoder, KE; Crowell, KR; Shaffer, ML; McMillan, HS; Carlson, LC; Dilworth, DA; Berlin Jr, CM (2004). "Effect of Dextromethorphan, Diphenhydramine, and Placebo on Nocturnal Cough and Sleep Quality for Coughing Children and Their Parents". Pediatrics 114 (1): e85–90. doi:10.1542/peds.114.1.e85. PMID 15231978.
- ^ Brooks, BR; Thisted, RA; Appel, SH; Bradley, WG; Olney, RK; Berg, JE; Pope, LE; Smith, RA; Avp-923 Als Study, Group (2004). "Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial". Neurology 63 (8): 1364–70. PMID 15505150.
- ^ "Cough Drug May Help Fibromyalgia Pain". WebMD.
- ^ H. Koyuncuoǧlu, M. Güngör, H. Saǧduyu, F. Aricioǧlu (Apr 1990). "Suppression by ketamine and dextromethorphan of precipitated abstinence syndrome in rats". Pharmacol Biochem Behav. 35 (4): 829–32. doi:10.1016/0091-3057(90)90366-P. PMID 2345761.
- ^ a b c "Dextromethorphan (DXM)". Cesar.umd.edu. Retrieved 2013-07-28.
- ^ White, William. "The DXM Experience". Erowid.org. Retrieved December 21, 2010.
- ^ AJ Giannini. Drugs of Abuse--Second Edition. Los Angeles, Practice Management Information Corp, 1997.[page needed]
- ^ Erowid DXM (Dextromethorphan, DM) Vault, Erowid.org
- ^ a b c d e "Dextromethorphan". NHTSA.
- ^ Olney, J.; Labruyere, J; Price, M. (1989). "Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs". Science 244 (4910): 1360–2. doi:10.1126/science.2660263. PMID 2660263.
- ^ Carliss, R; Radovsky, A; Chengelis, C; Oneill, T; Shuey, D (2007). "Oral administration of dextromethorphan does not produce neuronal vacuolation in the rat brain". NeuroToxicology 28 (4): 813–8. doi:10.1016/j.neuro.2007.03.009. PMID 17573115.
- ^ WHO Expert Committee on Drug Dependence (1970). Seventeenth Report (PDF). World Health Organization. Retrieved 2008-12-29.
- ^ Schwartz, AR; Pizon, AF (2008). "Dextromethorphan-induced serotonin syndrome". Clinical Toxicology (Philadelphia) 46 (8): 771–773.
- ^ "Inhibitors of CYP3A4". http://www.ganfyd.org/index.php?title=About_us. Retrieved 23 August 2013. (primary sources are cited therein but I lack PubMed access to check them)
- ^ a b c Chou, Y; Liao, JF; Chang, WY; Lin, MF; Chen, CF (1999). "Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextromethorphan and dextrorphan". Brain Research 821 (2): 516–9. doi:10.1016/S0006-8993(99)01125-7. PMID 10064839.
- ^ Wong, B; Coulter, D; Choi, D; Prince, D (1988). "Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-d-aspartate in brain slices". Neuroscience Letters 85 (2): 261–6. doi:10.1016/0304-3940(88)90362-X. PMID 2897648.
- ^ Church, J; Jones, MG; Davies, SN; Lodge, D (1989). "Antitussive agents as N-methylaspartate antagonists: further studies". Canadian journal of physiology and pharmacology 67 (6): 561–7. doi:10.1139/y89-090. PMID 2673498.
- ^ Kamel, Ihab R.; Wendling, Woodrow W.; Chen, Dong; Wendling, Karen S.; Harakal, Concetta; Carlsson, Christer (2008). "N-Methyl-D-Aspartate (NMDA) Antagonists—S(+)-ketamine, Dextrorphan, and Dextromethorphan—Act as Calcium Antagonists on Bovine Cerebral Arteries". Journal of Neurosurgical Anesthesiology 20 (4): 241–8. doi:10.1097/ANA.0b013e31817f523f. PMID 18812887.
- ^ Damaj, M. I.; Flood, P; Ho, KK; May, EL; Martin, BR (2004). "Effect of Dextrometorphan and Dextrorphan on Nicotine and Neuronal Nicotinic Receptors: In Vitro and in Vivo Selectivity". Journal of Pharmacology and Experimental Therapeutics 312 (2): 780–5. doi:10.1124/jpet.104.075093. PMID 15356218.
- ^ Lee, J; Shin, E; Jeong, S; Kim, J; Lee, B; Yoon, I; Lee, J; Choi, S; Lee, S (2006). "Effects of dextrorotatory morphinans on α3β4 nicotinic acetylcholine receptors expressed in Xenopus oocytes". European Journal of Pharmacology 536 (1-2): 85–92. doi:10.1016/j.ejphar.2006.02.034. PMID 16563374.
- ^ Hernandez, SC; Bertolino, M; Xiao, Y; Pringle, KE; Caruso, FS; Kellar, KJ (2000). "Dextromethorphan and its metabolite dextrorphan block alpha3beta4 neuronal nicotinic receptors". The Journal of Pharmacology and Experimental Therapeutics 293 (3): 962–7. PMID 10869398.
- ^ a b Codd, EE; Shank, RP; Schupsky, JJ; Raffa, RB (1995). "Serotonin and norepinephrine uptake inhibiting activity of centrally acting analgesics: structural determinants and role in antinociception". The Journal of Pharmacology and Experimental Therapeutics 274 (3): 1263–70. PMID 7562497.
- ^ Schwartz, AR; Pizon, AF; Brooks, DE (2008). "Dextromethorphan-induced serotonin syndrome". Clinical toxicology (Philadelphia, Pa.) 46 (8): 771–3. PMID 19238739.
- ^ Henderson, M; Fuller, RW (1992). "Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats". Brain Research 594 (2): 323–6. doi:10.1016/0006-8993(92)91144-4. PMID 1280529.
- ^ Gillman, P. K. (2005). "Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity". British Journal of Anaesthesia 95 (4): 434–41. doi:10.1093/bja/aei210. PMID 16051647.
- ^ Zhang, W. (2004). "Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase". The FASEB Journal: 589–91. doi:10.1096/fj.03-0983fje.
- ^ Schmider, J. R.; Greenblatt, D. J.; Fogelman, S. M.; Von Moltke, L. L.; Shader, R. I. (1997). "Metabolism of Dextromethorphan in vitro: Involvement of Cytochromes P450 2D6 and 3A3/4, with a Possible Role of 2E1". Biopharmaceutics & Drug Disposition 18 (3): 227–240. doi:10.1002/(SICI)1099-081X(199704)18:3<227::AID-BDD18>3.0.CO;2-L. PMID 9113345.
- ^ Professor Alyn H Morice paper titled 'Cough' par. 'Dextromethorphan' http://www.issc.info/cough.html
- ^ Professor Alyn H Morice paper titled 'Cough' http://www.issc.info/cough.html
- ^ a b c d Yu, A; Haining, RL (2001). "Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?". Drug metabolism and disposition: the biological fate of chemicals 29 (11): 1514–20. PMID 11602530.
- ^ Capon, Deborah A.; Bochner, Felix; Kerry, Nicole; Mikus, Gerd; Danz, Catherine; Somogyi, Andrew A. (1996). "The influence of CYP2D6 polymorphism and quinidine on the disposition and antitussive effect of dextromethorphan in humans*". Clinical Pharmacology & Therapeutics 60: 295–307. doi:10.1016/S0009-9236(96)90056-9.
- ^ Woodworth, JR; Dennis, SR; Moore, L; Rotenberg, KS (1987). "The polymorphic metabolism of dextromethorphan". Journal of clinical pharmacology 27 (2): 139–43. PMID 3680565.
- ^ "Memorandum for the Secretary of Defense" (PDF). Retrieved 2013-07-28.
- ^ "The resolution of 3-hydroxy-and 3-methoxy-n-methyl-morphinanes and process for the manufacture of the latter" Patent No- GB684367A and "Process for the preparation of optically active 3-methoxy-n-methylmorphinans and salts thereof" Schnider O and Grüssner A (inventors). US Patent 2676177. 20 April 1954. Retrieved 2011-02-08
- ^ http://www.leginfo.ca.gov/pub/11-12/bill/sen/sb_0501-0550/sb_514_bill_20110831_chaptered.pdf
External links[edit]
- U.S. National Library of Medicine: Drug Information Portal - Dextromethorphan
- Nuedexta (dextromethorphan hydrobromide and quinidine sulfate): Prescribing Information (Original Approval Date FDA: October 29, 2010)
- DXM at Erowid


text:
B-Stock Pedals
Pro Guitar Shop wants to help save you a little cash money on your journey to sonic utopia—we're now offering B-stock pedals for purchase! What's a "B-stock" pedal, you ask?! B-stocks are pedals that work perfectly, but… may have some cosmetic imperfections. This could mean: a flaw in the finish, a gouge in the enclosure, complete lack of original packaging, or any of a number of other conditions that prevent the pedal from being "A Stock." B-stock pedals are fully tested to ensure that they function normally. They're just a little less pretty. And a lot less expensive.
B-stock pedals come with a full manufacturer's warranty, but please note that B-stocks are not covered by PGS' 1 Year Warranty and: all B-stock sales are FINAL.
Coupon Codes are not valid on B-Stock Merchandise.
Boss RC-30 Loop Station B-Stock
The Boss RC-30 Loop Station is the latest innovation in compact looper pedals. Featuring two recordable tracks, USB 2.0, and up to three hours of recording time, the Boss RC-30 Loop Station is a monstrously powerful looping tool for practice, recording, or live use.Regular Price: $299.00
Special Price: $233.22

subset: commoncrawl


text:
Rollover Photo to Zoom
Rooster Tablecloth
Add Country Charm To Your Table With Our Whimsical Rooster Tablecloth
Rooster Tablecloth
Add Country Charm To Your Table With Our Whimsical Rooster Tablecloth
$19.95 - $24.95
Brighten and refresh your kitchen, dining, or picnic table with our all-season rooster tablecloth. This made-to-last table covering will not pill or fade, never needs ironing, and is easy-care machine wash and dry, thereby leaving you more time to enjoy summer's outdoor festivities. Polyester. Imported.
- No-iron tablecloth
- Adds country charm in an instant
- Easy care machine wash and dry
- Will not pill or fade
Our rooster tablecloth sets your table in country style and with lasting quality for you and your family to enjoy for years to come.
Rooster Tablecloth
I love Roosters
Anything that has rooster motifs / or the like I absolutely love be it dishes, clothing, bed and bath linens etc.
May 15, 2013
1-1 of 1


text:
Microtel Inn & Suites Beckley East
Travel Blogs from Beckley
White Water Rafting
After leaving camp at 7am we headed to Lansing in West Virginia, about 5h drive away! We got there just in time for our tour to set out in the bus down to the river. In all we went down about 14 rapids, all varying from grade 1-5 in difficulty with me on falling out twice at the same rapid! It was such a great ...
Travels with Nick
... Sunday we drove into Beckley and visited the mine exhibition which was enjoyable and very informative. The tour was conducted by a retired miner who was able to give us his perspective on a coalminers life. We decided to drive the car and rv down the mountain separately this morning which was easier on both of us. We are heading home from here because John is having major problems with his knee. The mine tour yesterday included some walking and he was hurting when we got ...
A quick and fun family visit!
I am traveling my first few miles for this blog tomorrow morning! I am privleged to see both my wonderful Aunt Peggy and cousin Robert! Peggy I am looking forward to experiencing Tamarack tomorrow. More shall be written after I have experienced it.
Stuck in the mud
... to go through the mud puddles slowly, so no need to power through. Once I understand this I stop freaking myself out and actually enjoy the experience.
Dad I felt like I was on that little blue car racing around the house again as a young child - fearless!
Once you are covered in mud it doesn't matter how much more mud you splash through, you just want to do it - it was so much fun.
White Water Rafting - woohoo!
This morning we have an early buffet breakfast at 6:30am as we have to be assembled by 7:30am for our rafting day trip. It is cold and raining today so we are going to be wet all day. We suit up with our personal floatation device, helmets and paddles and take a 10 minute bus ride to the Lower New River for a full day of rafting where we will experience category 3, 4 and 5 rapids. We have been told Niagara Falls is considered category 6 so category 5 is huge and ...


text:
Aloha there at our free ringtones website, where you may search for the best ringtones for your smartphone. Today we have a ringtone of "ghost of freedom" by Iced Earth as well as 192 other ringtones by Iced Earth. "ghost of freedom" is one of the best tracks from the "Horror Show" album that was made by Iced Earth at their studios together with other 12 tracks. You can listen to all 5 Iced Earth – "ghost of freedom" ringtone variations available here and download it for free right here. You can also choose from other 14 albums produced by Iced Earth for all time. "ghost of freedom" is referred to Power Metal, and we bring you a huge amount of Power Metal melodies absolutely for free. And finally, we have collected lyrics for this track and you can view it here as well. So feel free to browse, listen, download ringtones at Audiko.net. Make your phone sound cool!
Iced Earth ghost of freedom Ringtone
Similar Ringtones
Browse Genres
Heavy Metal Metal Power Metal Speed Metal Thrash Metal progressive metal
Albums by Iced Earth
Top ringtones by Iced Earth
New ringtones
- Spiel mir das lied vom Tod - Lied vom Tod
- - prince royce - Prince Royce - Stand By Me
- 3m8s - Don't You Worry Child - Swedish House Maffia
- Nazar - Sweet 16 feat. Projekt Elias
- Nazar - Pyramiden Hinterm Mond feat. Projekt Elias
- Optiv & CZA - In Too Deep
- Bicycle Horn Sound Effects - Bicycle Horn Sound Effect Ringtone
- Volxsturm - Nur wir 2
- 乧뭬 - 倀漀爀挀攀氀愀椀渀 倀爀椀渀挀攀猀猀ᤠ 倀愀氀愀挀攀
- hey hey - v


text:
Homemade Valentine Trail Mix with PRINTABLE Tags for Kids
After Monday's post, Chocolate Pomegranate Petit Fours, which are very chic, yet very time consuming, I thought I'd post something quick and easy. No cooking or baking today; just a simple dump and stir homemade trail mix recipe that makes an exciting Valentine snack to send to school.
This Valentine snack is a great filler for goodie bags. Mix the homemade trail mix, scoop into snack-sized bags, then add a fun tag.
Generally, I'm NOT very crafty. The craftiest I get is making paper flowers for cupcake toppers or trying to paint fondant gnomes. So if I can create Valentine cards with my kids, YOU can make Valentine cards too!
For these sweet Valentine bag tags, I used clip art from Cocoa Mint, and online store that offers cute clean graphics and printable invitations, party supplies, and digital backgrounds. The clip art allowed me to FEEL crafty, when really all I did was cut and paste …with my mouse. Thanks Cocoa Mint!
You can make your own, or use mine. Either way, this Valentine Snack will be the hit of the party.
To Use My Tags:
- Click Here to Print. (Cardstock recommended.)
- Cut each sheet in half, then trim approximately 3/4 inch off each side to match the width of the snack bags.
- Fold each card in half and use glue dots or a stapler to attach them to the tops of the bags. (We also used a paper punch to round the corners.)
- Voila!
This is a great Saturday project. The kids literally did everything from mixing to glue-dotting. They are SO excited to share these original Valentines with their friends.
This homemade trail mix has all the right ingredients for pure Valentine joy. I left out the nuts in traditional trail mix to keep it safe for the classroom, but the pretzels offer a salty bite to balance the sweetness. This is good stuff!
Yield: 34 - 1/2 cup servings
Prep Time: 5 minutes
Homemade Trail Mix ~ Valentine Snack
4 cups miniature pretzels
4 cups Strawberry Yogurt Cherrios (or favorite cereal)
3 cups (1 box) Chocolate Teddy Grahams
2 cups dried cherries or cranberries
2 cups yogurt covered raisins
2 cups Valentine M&Ms
Dump all the ingredients in a large bowl and mix.
Use a 1/2 cup scoop to pour into snack-size zip bags.
More Valentine Ideas:
Rose Cake ~ I Am Baker
Peanut Butter Heart Cookies ~ Created By Diane
Red Velvet Cheesecake Milkshakes ~ The Novice Chef
Strawberry Lemonade Vodka ~ Live Love Pasta
Related Posts
64 Responses to "Homemade Valentine Trail Mix with PRINTABLE Tags for Kids"
Hi Sommer,
Have to comment sorry. I came across this on Pinterest. Want to mention that while you "left out" the nuts to make this snack "safe" for the classroom, its actually NOT (if targeting nut allergies). Several of the ingredients are EXTREMELY high risk for an allergic reaction for anyone with a peanut / tree nut allergy (may actually contain the allergens).
Cannot find the Pin at the moment. Had tried to comment on it earlier. The Pinterest label calls this a "Nut free and safe snack for the classroom."
Sorry ….. but otherwise its very cute.
That is exactly what I was thinking!
Agree. Many of these items were made in a facility that also makes things with Nuts; M&M's & yogurt covered raisins being the big ones.
Very cute though
Just thought I'd let you know I included a link to your trail mix on my personal blog. Such a cute idea! Thanks for the post!
Amy Senter
Pingback: MiszelkowySchowek's soup
Pingback: Handmade Valentines Ideas
Pingback: Happy Valentine's Day Trail Mix «
Pingback: Dollar Store Crafts » Blog Archive » 101 Valentine's Day Treat Ideas
Pingback: 20 Blogs with the Best Make Your Own Valentine Ideas | Babysitters
Pingback: 20 Blogs with the Best Make Your Own Valentine Ideas
Pingback: Valentine's Day Party Planner
Pingback: 20 Blogs with the Best Make Your Own Valentine Ideas | TeacherTime123
Pingback: Topiary Intro | Adventures in Motherhood
Pingback: DIY Valentines For Kids ~ 5 Fun And Easy Ideas! | Child Mode
Pingback: thursday things - the improved door, limited edition oreos, and a valentines round up | wee eats


text:
FCB President Pat Dee tells SFR his bank is adequately capitalized, blaming its...problems on the economy. "You can say in hindsight we did more residential construction and land development loans than we should have, but three or four years ago, nobody foresaw the problems we're having today," Dee says.
First State Bankcorp CEO Michael Stanford will resign Dec. 31 for unclear reasons, Global Finanacial Newswires reported Tuesday morning (Dec. 22).
As the parent company for New Mexico's First Community Bank branches, the ramifications of the resignation have yet to be clarified by Taos First Community Bank or from the branch's officials in Albuquerque — all of whom were unavailable for comment Tuesday morning.


text:
Gary HallRegional Director email@example.com (641) 425-3116 Agriculture, Natural Resources, 4-H and Youth, Horticulture and Community Resource Development |
Dennis JohnsonCounty Extension Education Specialist email@example.com (641-324-1531) 4-H and Agriculture Education |
Mindy TenoldWorth County Youth Coordinator firstname.lastname@example.com 641-324-1531 4-H Youth Development |
Mary ClagettOffice Manager firstname.lastname@example.com 641-324-1531 Office Management |
Gail Castillo4-H Youth Development Specialist email@example.com 641-423-0844 Youth and Youth Programs |
Nancy ClarkNutrition & Health Field Specialist email@example.com (515) 295-2469 Food Safety, Nutrition Throughout the Lifecycle, Consumer Food Management, Women's Health Issues, Nutrition and the Teen Athlete, Sun Exposure and Cancer Risk, Dining with Diabetes |
M. Susan EricksonExtension specialist, Department of Landscape Architecture, and Partnering Landscape and Community Enhancement (PLaCE) program coordinator firstname.lastname@example.com (515) 294-1790 Healthy community design, therapeutic gardens |
Russ EukenLivestock Field Specialist email@example.com 641-923-2856 Production information related to nutrition, facilities, health, records, and budgeting for swine beef, sheep and dairy producers. Computer applications for livestock production. Individual consultation on improving productivity in livestock operations. Environmentally sound livestock production methods. |
Dan HuyserField Specialist/Agricultural Engineering email@example.com 515 298-1731 Livestock facilities, building materials and construction ventilation systems, manure management systems, soil erosion and crop residue management, soil and water conservation, ground water quality, well construction and maintenance, farm machinery, environmental regulations, energy conservation and farm safety. |
Mark JohnsonCrops Program Specialist email@example.com (515) 979-9578 Integrated Crop Management, Corn and soybean management, Soil fertility, Alfalfa, Tillage systems, Integrated Pest Management - weeds, insects and crop diseases, Soil surveys. |
Kelvin LeiboldISU Extension Farm Management Field Specialist email@example.com (641) 648-4862 Farm Management including - farm leasing and land value, intergenerational transfers of assets, farm business financial planning and analysis, debt restructuring, crop and livestock marketing strategies and outlook, computerized 'what if' analysis for expansion or restructuring. |
Brenda MartinCIRAS Account Manager email@example.com 515-570-5282 Center For Industrial Research & Service, ISU Extension & Community Colleges of Iowa |
Jolene McCoyCommunications & External Relations firstname.lastname@example.com 515-306-2828 Public relations. |
Malisa RaderFamily Life Program Specialist email@example.com 515-832-9597 Malisa's primary areas of interest include early care and education, early intervention, parenting education, attachment caregiving, and working with culturally diverse families. |
Brenda SchmittFamily Resource Management Field Specialist email@example.com 641-423-0844 Provides educational programs on managing financial and personal resouces throughout life. |


text:
Eating healthy isn't just for babies! Earth's Best offers products such as organic milk and Sesame Street breakfasts, meals and snacks for your "big kid." Look for on-the-go options, like individually packaged apple sauces and whole grain bars, perfect for busy kids at school!
Healthy snack alternatives that are a wholesome way to meet children's nutritional needs.
Soups, pizza and frozen entrees that are convenient for parents and delicious and fun for kids.
Great tasting organic french toast sticks, cold cereals, instant oatmeal and frozen mini waffles to fuel kids for the day.
Nutritious snacks made from organic fruit and real organic yogurt. Perfect for on the go.
A naturally sweet snack made with 100% organic apples to offer delicious taste and superior nutrition.


text:
Senior journalists of his media group were in attendance when Haryana politician Venod Sharma, addressed his first rally at Kurukshetra (March 9) after quitting the Congress party. That included resident editors and bureau chiefs of his media properties: Sunday Guardian, India News Haryana, and the newspaper Aaj Samaj. For other media, the event was covered by their local correspondents.
Both the ET and TOI claim they have an exclusive interview (on March 10) with Microsoft CEO Satya Nadella. While TOI claims that their's is the" first with any Indian newspaper or TV channel" since his appointment, ET says it is an email interview.
Twitter on March 8 night was erupting with agitated tweets from BJP workers and followers after word got around of the tweet put out by NDTV about Sushma Swaraj, which it later withdrew. The channel tweeted about Swaraj saying 'if there is a Modi wave in India why is he looking for a safe seat in UP'? It then put out a correction saying Sushma did not tweet this. The BJP announced a boycott of NDTV. Didn't say for how long.


text:
Tax the Rich – and Limit Retirement Contributions? It Doesn't Add Up.
Tax the rich! Raise their rates! Limit their deductions! That seems to be the populist mantra. It's perpetuated in the press, and there's some indication that the general public seems to support the idea. Now middle class workers with higher than average incomes seem to be caught up in discussions defining those that are "rich."
As this applies to tax-exempt organizations, we're talking about hospital administrators, educators, executive directors of local community and other charitable organizations – people who generally earn a better than average income, yet by no stretch of the imagination do their incomes compare to Warren Buffett's. And when it comes to the impact on their employers' retirement plans, shouldn't the tax structure support retirement readiness for those who have dedicated their careers to giving back to their communities?
For example, current conventional belief supports that people should be saving 11-15% of their pay, including matching contributions, every year throughout their working careers in order to save enough to be retirement ready(1)(2). Assuming a 3% match, and therefore an average of a 12% annual savings need, anyone earning less than approximately $146,000 annually should be fine. (12% of $146,000 is approximately the $17,500 annual limit.)
However, what about the person making $250,000 per year? Contributing a maximum of $17,500 only equates to 7% of pay. When the match is included it's still short of the target necessary for retirement readiness—yet as the numbers show, these limitations currently in place put these people at a disadvantage for retirement savings. In addition, one of the alternatives under consideration is limiting qualified plan contributions even further.
Fortunately, there is something that can be done. Private (non-governmental) tax-exempt organizations can maintain a deferred compensation plan under section 457 of the internal revenue code. These 457 plans allow for additional benefits for a select group of management or highly compensated individuals, over and above the limitations in their 403(b) or 401(k) plan.
457 plans are an excellent tool for tax-exempt organizations to be able to recruit, retain, reward and retire key personnel. In other words, they help meet the goals of the organization (which in turn, serves their communities) while empowering key employees to meet their financial goals.
For additional insight, check out this video by John Baergen that provides a primer on 457 plans. http://www.youtube.com/watch?v=c-ElTzQeB6c&feature=youtu.be
Last summer, Senator Tom Harkin released a report called "The Retirement Crisis and a Plan to Solve It." One premise of the report is that there is inadequate savings for Baby Boomers and Gen Xers to pay for basic expenses in retirement. The report footnotes studies that show this "retirement income gap" is between $4.3 and $6.6 trillion, but as we see above, there is already pressure in regular tax rules that make it difficult for higher-than-average income people to achieve retirement readiness.
As Congress continues the tax debate, it's important that we consider what's good for the long term, and helping all plan participants achieve retirement readiness should be of paramount importance. Tax reform and retirement policy should not be at odds.
In addition to blogging here, I also tweet regularly about topics of interest to Tax Exempt plans. Follow me on Twitter: @1aaronfriedman1.
Click here to follow my Tax Exempt blog
(1) Research with Financial Advisors, June 2011, conducted by Harris Interactive on behalf of the Principal Financial Group®.
(2) Our View on Retirement Readiness: How to Move from a "Popular" Plan to a Successful Plan, the Principal Financial Group, September 2011. The estimate assumes a 40-year span of accumulating savings, as well as the following facts: Retirement at age 65; Social Security providing 40% replacement of income; annual market returns of 7%; annual inflation of 2.5%; annual wage growth of 3.5% over 40 years in workforce. This estimate is based on a goal of replacing 85% of salary. The assumed rate of return for the study was hypothetical and does not guarantee any future returns nor represent the return of any particular investment. Contributions do not take into account the impact of taxes on pre-tax distributions.
While this communication may be used to promote or market a transaction or an idea that is discussed in the publication, it is intended to provide general information about the subject matter covered and is provided with the understanding that none of the member companies of The Principal are rendering legal, accounting, or tax advice. It is not a marketed opinion and may not be used to avoid penalties under the Internal Revenue Code. You should consult with appropriate counsel or other advisors on all matters pertaining to legal, tax, or accounting obligations and requirements.
Insurance products and plan administrative services are provided by Principal Life Insurance Company. Securities are offered through Princor Financial Services Corporation, 1-800-547-7754, Member SIPC and/or independent broker dealers. Securities sold by a Princor® Registered Representative are offered through Princor. Princor and Principal Life are members of the Principal Financial Group® (The Principal®), Des Moines, IA 50392.
© 2013 Principal Financial Services, Inc.
HZ1304 t13012304fs
Andrew Martin #
The person making $250k simply saves the additional money needed to reach a 11%-15% target OUTSIDE of a qualified plan. What's the problem? It's not like they are forced to spend the money instead.
January 28, 2013-
Aaron Friedman, National Practice Leader - Tax-Exempt, the Principal Financial Group, Princor Registered Representative #
Good point. But the same thing could really be said about savers at any income level. Our national policy has been to encourage savings with tax deferral and consider we're not really talking about truly wealthy people here. Just high income middle class. There are already large pressures on these folks. In my example, we're talking about people contributing to the good of their communities.
January 29, 2013-
Andrew Martin #
I just don't see this as anywhere near the biggest problem we have with our lack of national savings or our national retirement policy. You've already mentioned that a 457 could be made available for these folk. Often a DB SERP is in place for an oh-BTW long-ago frozen or terminated DB plan. if neither, they can save on their own without a tax subsidy. I am more concerned about the average Janes and Joes, and how they are supposed to retire. The folks you mention will be fine under any scenario.
January 29, 2013 -
Aaron Friedman, National Practice Leader - Tax-Exempt, the Principal Financial Group, Princor Registered Representative #
I don't disagree with the priority. Retirement readiness for all is where we should be putting our efforts, and the tax debate distracts from that objective.
January 29, 2013


text:
Event Information
Special Report: Inside Confucius - Exhibit Closes
Date: Sunday, May 12th, 2013Time: 1:00am - 4:00pm
Location: Kentucky Museum - Window Gallery
The Confucius Institute is the Chinese government's flagship cultural outreach program. It is putting thousands of volunteer teachers in local classrooms all over the world to teach Mandarin, to spread the country's rich culture and to influence China's image with the next generation of global decision makers. Reported and produced by the fusion journalists of Western Kentucky University's School of Journalism & Broadcasting.


text:
While preparing for my vacation to Sao Paulo, Brazil, I wanted to dress comfortably for my 12 hour journey across the equator and I thought this was the perfect opportunity to show off my creation.
I made these pants in my Sewing, Level 1 class at the local community college.
Pattern Used – Burda(Style) young #7546
Click here for a short story and more pictures.
Linen, elastic
Dec 29, 2010, 06.30 PMby krossinamecom
I love these pants and would like to make a pair. How do I get the pattern? Thanks much
Dec 30, 2010, 02.23 AMby kelepso
I purchased this pattern from Joann's Fabrics. The Pattern Used is Burda Young #7546
Oct 19, 2010, 04.29 PMby rokonela
I love this kind of pants. I have bought a pair like this from Turkey this year, and I want to make another pair for my boyfriend. What pattern did you use?
Oct 20, 2010, 03.33 AMby kelepso
Thank you. It Burdayoung 7546. Give it a try. They were very easy to make.
Oct 13, 2010, 03.41 AMby marloncosta
Cool pants! They look confortable! Perfect for a long trip and for many other occasions when you would want to look cool and edgy! You carry those pants really well dude!
Oct 20, 2010, 03.33 AMby kelepso
Thank you Marloncosta
Oct 12, 2010, 07.12 AMby Ophelia K
Looks so great on you!!
Oct 20, 2010, 03.33 AMby kelepso
Thank you Ophelia K
Oct 12, 2010, 05.40 AMby Ralf Schmitz
love the pants and your choice of color and material! the look comfy, yet stylish! very nice!
Oct 20, 2010, 03.34 AMby kelepso
They are very comfortable. Thank you Ralf.
Oct 11, 2010, 12.35 PMby helluvaguy
They really look so cool and the color is fantastic. Sure they must be comfy. Did I see it right that you used some elastic tape on the knee end?
Oct 11, 2010, 01.12 PMby kelepso
Yes, the pattern called for elastic at the legs of the pants, just below the knee. I will post the pattern # later. It's by BurdaStyle. Thank you again for your comments.
Oct 11, 2010, 08.19 AMby Zane Tanqueco
cool get up!
Oct 11, 2010, 01.12 PMby kelepso
Thank you
Oct 11, 2010, 03.45 AMby nettie
That looks like a very comfy, and chic, traveling outfit! I love the color of the pants!
Oct 11, 2010, 01.13 PMby kelepso
Thank you
Guest Columns
Behind the seams with Marina von Koenig Part 2
Backstage Report
Get all 11 of these retro inspired patterns for one low price!
Pattern of the Week
Hippie meets grunge in this plaid top with flared sleeves and a round neckline.
Editors' Pick
Leopard and snakeskin are the new neutrals.
Member Project of the Week
Peneloping's hand beaded frock is a real stunner.


text:
Search this blog
Recent Posts
Latest Comments
- On A noble cause: Repairing Wikipedia's Geology articles:
- Tobias Probus: Hi there! Someone in my Facebook group shared this website with us so I came to look it over.... (14 days 4 hours ago)
- cheats secrets: I have witnessed that good real estate agents almost everywhere are warming up to FSBO... (18 days 5 hours ago)
- More Info: I was just searching for this info for a while. After six hours of continuous Googleing, finally I... (18 days 5 hours ago)
- Boyce Frasher: Do you have a spam issue on this blog; I also am a blogger, and I was wanting to know your... (23 days 9 hours ago)
- wordpress blog hosting: Hi, always i used to check weblog posts here early in the dawn, for the reason that i... (58 days 9 hours ago)
- gratis sexdate: Talking about this stuff puts a smile on my face! (71 days 21 hours ago)
- log cabins jasper: I'm not that much of a online reader to be honest but your blogs really nice, keep it up!... (79 days 3 hours ago)
- remove pimples: First off I want to say great blog! I had a quick question in which I'd like to ask if... (92 days 12 hours ago)
Latest from the Geoblogosphere
Tag Archives: hypogene
(NOTE: I would like to thank Chris @ Highly Allochthonous for giving me this opportunity to cross-post a favorite sedimentary-stratigraphy class project (from 2007) on Earth Science Erratics. All mistakes are mine and I welcome comments. ESE is a great … Continue reading
Categories: Ore geology, Rocks & minerals


text:
Training - Calendar of Events
Transfer Station Operator's Training
Date: June 25, 2013
Time: 9:00 AM - 4:00 PM
Location: Augusta, Response Bldg. 4 Blossom Lane
Contact: Sandy Moody, (207) 287-7751
Core Session 3
The Department is announcing a presentation of core training session number 3, Hazardous and Special Waste open to all. This will be a one-day workshop for municipal transfer station operators, commercial operators, selectmen, town managers, and others interested.
We have used a PowerPoint slide presentation of operational issues at transfer stations around the State in previous training sessions on this topic. The slides lead participants through a visual discussion of how to operate a transfer facility and provide an opportunity to learn from others' successes and mistakes. This presentation is periodically updated to include new slides focusing on the most recent challenges to transfer station operation. Please register to join us soon because space is limited at some locations. Directions to locations are available on our web site or upon request:
November 1, 2012 Augusta: DEP Response Training Room, 4 Blossom Lane, by the Big Smoke Stack November 6, 2012 Brewer: Jeff's Catering, 15 Littlefield Way, East West Industrial Park November 9, 2012 Caribou, Northern Maine Dev. Commission, 11 W. Presque Isle Road November 15, 2012 Portland, DEP Conference Room 4, Canco Road, Portland (please enter at the back of the building)
Lunch and Refreshments will be served. Registration begins at 8:15 a.m. Program begins promptly at 9:00 a.m. and ends at 4 p.m. Registration fee is $25.00 per person including lunch, refreshments, and materials. Please make your check payable to Treasurer, State of Maine. Please return your registration before October 30 or we cannot guarantee you a seat. Please contact Sandy Moody at 207-287-7751 if you need assistance with registration, cannot attend or wish to change locations after registering.


text:
Whoops! Something went wrong trying to count your new vote. Please try again.
100 Carondelet Plaza, St Louis, MO
Vote for a Chance to Win a Dream Spa & Beauty Package! Voting automatically enters you into the drawing. Click here for more info.
Counting your vote...
Hey now! We're using Facebook to authenticate your vote. Making sure you've got a pulse and aren't Spammy MacSpambot. After you log-in, you'll be good to go. Thanks for voting! Please sign in with Facebook to vote
The Ritz-Carlton, St. Louis
You voted for
999 N 2nd St, St Louis, MO
Four Seasons-St Louis
400 South 14th Street, St. Louis, MO
Sheraton St. Louis City Center Hotel and Suites
123 Front St, Labadie, MO
Hawthorne Inn
1019 Pine St, Saint Louis, MO
Omni Majestic Hotel
800 Washington Avenue, St. Louis, MO
Renaissance Grand Hotel
200 S 4th St, St Louis, MO
Millennium Hotel St. Louis


text:
The Financial Meltdown Does Not Slow Global Warming: Israel's Environmental Challenges and Innovative Emerging Solutions
You are cordially invited to a special guest lecture by Dr. Miriam (Miki) Haran, former Director General of the Israel Ministry of the Environment, Head of the MBA Environmental Management Program at Ono Academic College and Chief Scientist of Tamarix Ventures which focuses on Israel-related Clean-tech investments.
Tuesday, December 02, 2008
UCLA Anderson School of Management
Keynote speaker:
Dr. Miriam (Miki) Haran
Dr. Miriam (Miki) Haran
"The Financial Meltdown Does Not Slow Global Warming:
Israel's Environmental Challenges
and Innovative Emerging Solutions"
and Innovative Emerging Solutions"
Tuesday, December 2
UCLA Anderson School of Management
UCLA Anderson School of Management
Reception & Hors d'oeuvre
Cornell Hall Atrium (D Building), UCLA Anderson School of Management
Opening words:
Room D301, UCLA Anderson School of Management
Mr. Ryan Matulka,
Co-Director of Net Impact Sustainable Technology, UCLA Anderson Net Impact
Ms. Alma Gadot-Perez,
Israel Center Project Manager, Milken Institute and Net Impact Ambassador to Israel
Discussion and Q&A
Prof. Matthew E. Kahn,
UCLA's Institute of the Environment, the Department of Economics and the Department of Public Policy
Free admission, Please RSVP at:
Cost: Free of charge
Special Instructions
Parking is available for $9 and may be purchased at the parking kiosk located at the corner of Hilgard and Wyton Avenues.
Sponsor(s): Younes and Soraya Nazarian Center for Israel Studies, UCLA Leaders in Sustainability Program, UCLA Anderson Net Impact
<< | March 2014 | >> | |||||||||||||||||||||||||||||||||||||||||||||||||


text:
Search Result
Search Tags: Ottmar Liebert
Ottmar Liebert, guitar master, performs Saturday at Birchmere
Guitarist and composer Ottmar Liebert helped to establish "new flamenco" music in the early '90s. Think flamenco guitar mixed with Latin, jazz, and even Middle Eastern influences.
Friday - 05/31/2013, 08:58am EDT
Tags: tim bracken, backstage, birchmere, Alexandria


text:
Tanya_Birklid19's Station
What will I do?
8 commentsabout me
I'm a freshman at NDSU (North Dakota State University) and . . . I LOVE PYTHON!! Also, I'm a theatre major and loving it, I love Shakespeare, horror movies, Doctor Who, British comedy, my red pair of Chucks that I have, and I like to ride horse.
Friends Tabs
- friends
- Tanya_Birklid19's friends
my top 5
- groups
- Tanya_Birklid19's groups


text:
Mailing & Fulfilment
At the heart of Robell's operations is a highly-efficient warehousing and fulfilment facility based just off the M5 in Cheltenham. Our fulfilment house, combined with an excellent customer service and data entry team have the flexibility to handle just about any requirement.
Brochures, Catalogues, Coupons & Ecommerce
Whether you require Brochure mailings, Catalogue mailings, Coupon Redemption campaigns, Ecommerce Management or email campaigns, Robell have the track record and experience to make sure your campaign is handled with the efficiency and dedication needed.
20 Years of Experience
With over 20 years of dealing directly with the public, we how the importance of customer service. We make sure we treat our clients' customers with care and support needed, not just to give them a good service, but to encourage repeat purchasing in the future.


text:
the Twlight Special
The vampires among us
Fast on track to make the decision already and move to Oregon for the lush scenery, Wendy Parker discovers an undead revolution in our midst.
Overdrive's Most Beautiful contest is back for a second year. Submit yourself or a female truck driver you know! The first-place winner will win a trip to The Great American Trucking Show in August and will be featured in a story in Overdrive. Submissions accepted through March 20.
Editor's Picks
Stay Connected
Sign up to get Overdrive's daily newsletter.


text:
Hi guys what do you think about my new personal brand?
No offense, but…"Elite Author"? That's a reputable honor here on TF, not something authors assign to themselves.
am_themes said
No offense, but…"Elite Author"? That's a reputable honor here on TF, not something authors assign to themselves.
Its a joke. read under elite author
Misleading, and reported for staff to gve opinion.
Only on the basis that it intimates you are an envato elite author
- United States
- Sold between 250 000 and 1 000 000 dollars
- Has been a member for 6-7 years
- Referred between 200 and 499 users
- Bought between 100 and 499 items
- Author was Featured
- Microlancer Beta Tester
- Exclusive Author
I gotta agree – joke or not it reads as you being an elite author and that's a goal many have worked very hard to reach and others are also working hard to reach and have for some time. Don't quite see it as a "joke" sorry.
I see… Im sorry guys That wasn't my intention I will change it :/
I already changed it, again sorry for the misunderstanding
I'm gonna make myself new one, also..
Photoshoping zoomed in power elite badge, brb.
- Attended a Community Meetup
- Australia
- Bought between 10 and 49 items
- Community Ambassador
- Contributed a Blog Post
- Envato Staff
- Exclusive Author
- Grew a moustache for the Envato Movember competition
- Has been a member for 2-3 years
Hey guys, Ediartss didn't mean any harm. I know everyone is working hard to become Elite and many of you are well on your way, but let's make sure we aren't too harsh on other community members. If there's any misleading branding going around, just let me know and I'll sort it out.


text:
© Copyright by the designer Photographs, if shown, may reflect homeowner modifications
Open Living Spaces
Shutters, keystones and quoins lend this brick home a French sophistication. A fireplace is the focal point in the versatile Great Room. The island kitchen serves any meal in style. A whirlpool tub and a separate shower anchor the private bath in the master suite. Two adjacent garages offer plenty of space for vehicles and hobbies. This is a home you can live in for many years, since there are no stairs to climb.
First Floor:


text:
Current Specials
Special Offer:
$25.00 OFF Shipping
For a Limited Time Only: $25.00 OFF Shipping
The House Plan Shop is offering $25.00 OFF shipping on the initial purchase of any blueprint order over $550.00 (before shipping fees and taxes). Simply enter or mention this promotional code when placing your order: 02H14
Garage Plans Have Moved!
If you are looking for our garage plans, please check out our new site: thegarageplanshop.com.
Regular Office Hours
Saturday & Sunday:
Multi-Generational House, 027H-0036 |
Click image above to view larger |
Views may vary slightly from working drawings. Refer to floor plan for actual layout.
Design 027H-0036 |
Buy this House Plan Now! |
Plan Details
Plan Features
Plan Description
Simple lines and country charm give this narrow lot house plan a welcoming curb appeal. The main living areas are arranged on the first floor offering a step-saver kitchen with snack bar, convenient laundry access and an open floor plan. Three bedrooms and a deluxe bath reside on the second floor providing peace and quiet for everyone. On the finished lower level, you will be pleased with separate living quarters that work well for a mother-in-law or college suite. This space provides a compact kitchen, full bath, living area and a bedroom. Comfortable and functional, this two-story country home plan has plenty to offer.CAD files and reproducible masters not available in Quebec, Canada.


text:
Create a cloud-based trusted computing platform on Intel® processors for multi-tenancy and personal device use with software and hardware security.
Four IT managers discuss virtual desktop management models for four industries: financial services, education, healthcare, and general office.
Video: Oracle's Sun Fire X4470 M2* and Sun Fire X4800 M2* systems and Intel® Xeon® processor E7 family help redefine the enterprise data center.
Video: latest Cisco Unified Computing Systems* announcement based on Intel® Xeon® processor E7 family.
Video: intelligent PCs based on Intel® Core™ vPro™ processors provide performance and mobility, while delivering IT with control and manageability.
Video: Intel and VMware discuss the virtualization business benefits.
Video: The First American Corporation builds energy-efficient data center with Intel® Xeon® processors, lowering utility costs and server sprawl.
NxTop*, Virtual Computer and 2nd generation Intel® Core™ vPro™ processors work to deliver a secure desktop virtualization solution.
Hear how Intel IT is developing desktop virtualization to give IT more control and give users greater flexibility.
Illustrates how higher performance cores provide significant advantages over lower performance cores, including operating costs and VM space.


text:
Go to Email & News to manage your email, search the web, stay up to date with current news and more.
Complete solutions to start or grow your business
with less than 20 employees.
Solutions to start, grow and build your
business with more than 20 employees.
Global and national enterprises, governments
and wholesalers
This is the last time your account was accessed. | |
Whether you qualify for our FiOS or Standard services, you will enjoy fast Internet,
an impressive lineup of HD channels and reliable phone service. Learn more.
Shop for the products you want, explore options and get the best offer available
when you order service online. Shop & Compare.
11-29-2009 11:21 PM - edited 11-29-2009 11:36 PM
I have 5 static IP Addresses, and I would like to run multiple webservers on my connection. I have 3 servers that are able to run Apache via Linux and Windows ala WAMP. I recently had my router replaced like last month, and I am using the following: MI424WR-GEN2 with firmware 20.9.0 and its fully updated. I was using the MI424WR Rev D prior to it going bad, and I could host multiple web servers just fine with each public IP statically routed to the static LAN IP on my private network, however, after this switch I am only able to run 1 webserver on my 20 Megabit Synchornous FiOS Business Class Connection. I have tried power cycling the modem, power cycling my computers and to no avail I cannot get the other servers to be contactable via outside my LAN.
What can I do to remedy this situation?
Solved! Go to Solution.
This has been fixed in the most recent router firmware.
Shop FiOS
Shop Standard Services
Account & Services
Email, News, & TV


text:
Information contained on this page is provided by an independent third-party content provider. WorldNow and this Station make no warranties or representations in connection therewith. If you have any questions or comments about this page please contact firstname.lastname@example.com.
SOURCE Born To Sell
Covered call investment tools selected under ultra-competitive Trading Software category
LONG BEACH, Calif., Dec. 12, 2013 /PRNewswire/ -- Born To Sell, LLC, the investment software development company, today announced it has been chosen as a finalist in the 2013 TraderPlanet STAR (Superior Trading And Resource) Awards in the Trading Software category.
(Photo: http://photos.prnewswire.com/prnh/20131212/PH31871-a )
(Logo: http://photos.prnewswire.com/prnh/20131212/PH31871LOGO-b )
Born To Sell's customizable covered call screener makes it easy for income-oriented investors to search hundreds of thousands of covered calls instantly. Results are displayed in a user-friendly format, saving investors a huge amount of research time and allowing them to quickly identify high yield opportunities. In addition, the covered call portfolio management features help investors maximize their time premium (income) capture each month.
"For the third time, TraderPlanet's decision to choose us a finalist in one of the most competitive categories is a strong endorsement of our ease of use, clean user interface, and value-added feature set. They recognize that investment software can be simple and powerful at the same time," said Mike Scanlin, CEO of Born To Sell.
Win $10,000 In Investment Software
As a bonus, everyone who votes in TraderPlanet's contest is entered to win $10,000 in investment software. Voting is open until January 31, 2014, and investors may vote once per day to increase their chances of winning.
To vote, go to the voting ballot page at http://www.traderplanet.com/l/FFd
Born To Sell is listed in the Trading Software category.
About Born To Sell
Established in 2009, Born To Sell is a software development company dedicated to making best-of-breed covered call investment tools for self-directed investors. Headquartered in Long Beach and privately funded, Born To Sell's subscription service helps income-oriented investors with trade selection and portfolio management. For more information, or to take a free trial, please visit https://www.borntosell.com.
Mike Scanlin, CEO
Born To Sell
(800) 434-6980
Read more news from Born to Sell.
©2012 PR Newswire. All Rights Reserved.
1100 Banyan Blvd.
FCC Public File About Us
All content © Copyright 2000 - 2014 Worldnow and WFLX. All Rights Reserved.
For more information on this site, please read our Privacy Policy and Terms of Service. |


text:
If you are already a guest or a member sign in below.
We are Australia's leading consumer organisation with over 160,000 members.
Set up by consumers for consumers, CHOICE is the consumer advocate that provides Australians with information and advice, free from commercial bias.
As vital today as when we were founded in 1959, CHOICE continues to fight for consumers and uncover the truth.
By mobilising Australia's largest and loudest consumer movement, CHOICE fights to hold industry and government accountable and achieve real change on the issues that matter most.
CHOICE doesn't accept advertising or sponsorship. This means we can uncover the truth about everyday consumer issues and provide practical advice to help consumers cut through the crap.
CHOICE is Australia's largest source of expert reviews. Based on unbiased analysis and rigorous testing, we help consumers compare products and services and select what's best for them.
Total Fat: <3g = ; 3.1g – 19.9g = ; <20g = Saturated Fat: <1.5g = ; 1.6g – 4.9g = ; <5g = Sugars: <5g = ; 5.1g – 14.9g = ; <15g = Sodium: <120mg = ; 121mg – 599mg = ; <600mg = ns: not stated Where available: A = Adelaide; B = Brisbane, M = Melbourne, P = Perth, S = Sydney, All = All previously listed capital cities.
Receive FREE email updates of our latest tests, consumer news and CHOICE marketing promotions.
Full results for all models are shown in the table below.


text:
Designer Faces: The Hair and Makeup At The Fall 2011 Marc Jacobs Show
How appropriate that Mr. Jacobs's runway show was on Valentine's Day...because we are definitely feeling the love! The clothes were feminine yet edgy—and so were the slick ponytails, downturned black eyeliner, and rosy-red blush. Using words like "perverse" and "demented" to describe the hair and makeup, hairstylist Guido and makeup artist François Nars created a look that was subversive and cool.
- Editors' Favorites: Week of 3.10.14
- 10 Beauty Looks Inspired From the 10 Times You Wanted to Be a Pop Princess
- How to Break Up With Your Hairstylist, What to Tip, and 9 More Awkward Beauty Situations, Solved
- Designer Faces: Valentino Fall 2014
- Designer Faces: Christian Dior Fall 2014
- Designer Faces: Chanel Fall 2014
- Clear-Skin Saboteurs: 7 Mistakes That Are Making You Break Out
- Designer Faces: Chloé Fall 2014
- Editors' Favorites: Week of 3.3.14
- The 10 Best Oscar Beauty Looks of 2014
- Designer Faces: Versace Fall 2014
- Designer Faces: Roberto Cavalli Fall 2014
- Designer Faces: Dolce & Gabbana Fall 2014


text:
The anti-theft system may cause a no start condition due to electrostatic discharge (ESD) affecting the wireless control module (WCM). There is an updated WCM to correct this issue.
Resources for the Repair and Maintenance of your Dodge Nitro R/T
Dodge Nitro R/T Models:
Dodge Nitro R/T Problems
Odor from HVAC vents
Some vehicles may develop a musty odor coming from the HVAC system, Dodge has issued a cleaner/disinfectant and a coating for the evaporator designed to inhibit bacterial growth.
Liftgate ajar switch issue
The courtesy lights and liftgate ajar light may illuminate intermittently. Our technicians tell us that switching the wires at the liftgate ajar switch connector will correct this condition.
Remote Keyless Entry May Not Work at Times
The remote start or keyless entry system may not function at times. A service repair kit is available which should correct this condition.
Check Engine Light With Code P0123 and/or P0222
The Check Engine Light may illuminate with code P0123 and/or P0222 when the vehicle is operated in below freeing temperatures. Our technicians tell us replacing the electronic throttle body and clean air duct should correct this concern.
Dodge Nitro R/T Questions and Answers
I need to replace one of the black roof rails because it is cracked. Where can I get one? How much does it cost? Is it an easy repair?
What is the basic cost for a 30,000 miles tune up on a 2007 Dodge Nitro?
does this vehicle year and style have a problem with transmission going between 80,000miles and 120,000
turned on. It was like the key turned on the accessory and power went on but the remote would not work. When I started the car, the engine light came on. It has done this in the past.
About 90% of the time I refuel gas gets every where. I have an 07 R/T and had a similar experience with my 05 Durango. There ended up being a recall for the fuel tank filler inlet. Before I peti...
Dodge Nitro R/T Reviews
The brakes in a nitro it not strong especific the hand brake
I enjoy my Nitro but after being spoiled by my PT cruiser (with all of its electrical outlets); I definitely miss this feature with the Nitro plus it could be better on gas mileage.


text: A beautiful feeling we've ever got in our life is only a tiny lovely sprinkling Heaven has made us a gift. If only we will open our heart and learn to understand its meaning better there certainly will be a great deal of gifts Heaven promises us. It's a pity we let ourselves sink into hatred of each other, our children learn and play alone without our loving guidance, our fellow man lives in prolonged sorrow and poverty and our earth is torn by our bombs and poisons. If only we hadn't done it all we could hope for another sprinkling of gifts from Heaven in our lives our next days.


text:
Artist: | Capital STEEZ |
Title: | Capital STEEZ |
Album: | Amerikkkan Korruption |
Producer: | Madlib |
Avg Rating: |
Self-titled songs aren't for the faint of heart. You've got to compress everything that makes you you into a few short minutes, all while providing an experience that leaves listeners craving more. On his first feature (a Booth-exclusive world premiere here in the Booth!) Capital STEEZ attempts this audacious feat—with (in my humble opinion) … Read More


text:
CNET Editors' review
Digital deejaying has skyrocketed in popularity over the past five years and it's no wonder why. Compared to a full vinyl setup with all the hardware and physical media it requires, an MP3-based mixing station is extremely simple and cheap. There's even free software to get you started, and one of the most popular programs available is Virtual DJ.
Virtual DJ is often packaged with USB-based hardware mixing consoles from the likes of Hercules and Numark, and, in fact, if you really want to delve into the full array of features, such devices are going to be a necessity--and they'll require a $99 license fee to upgrade to the Pro version of the software. That said, you can download the app for free by itself and make very basic mixes and playlists.
While the program isn't specifically geared at newbies, it is intuitive enough for a musically inclined individual to use right off the bat. Once installed, Virtual DJ automatically populates a folder tree in the bottom left corner where you can easily access your music collection. The bottom middle serves as a tabbed, multifunction area where you can browse tracks, sample music bites, add effects, and make recordings.
The top of the window is dominated by two digital turntables, which are distinguished by color: blue on the left and red on the right. Each one has the ability to cue, loop, adjust pitch, scratch, and shift (among other features). In the middle is the mixing console, where you can adjust the gain and master volume, as well as transition between the two tracks. Once the songs have been dragged and dropped into the console, a bar along the top displays the sound waves of each to help with visual mixing. There's also a video input option that lets you create montages to the music.
The stylish interface and high number of features score points, but learning how to use the program is a hit-or-miss proposition. To be perfectly honest, using it without mixing hardware (that is, just a mouse and keyboard) is a challenge, and not one we enjoyed, so we recommend hooking up a compatible USB controller. Also worth a look: the thorough online user guide.
Virtual DJ is free, fully featured, and well-laid-out. It's a useful option both for aspiring mixers and newbies.
VirtualDJ:Publisher's Description
From Atomix Productions:
VirtualDJ is the DJ software chosen by DJ brands such as Numark, Denon and Hercules. It is used around the world by bedroom DJs and professional superstars alike. With its cutting-edge beatlock engine, your songs will always stay on the beat, and you can work your mixes incredibly faster than any other DJ. The automatic seamless loop engine and synchronized sampler will let you perform astounding remixes on the fly. The video engine lets you mix and scratch music videos as easily as audio. With NetSearch and MusicGroups, you will stay on the edge of the musical trends. And with the versatile VDJScript language and hundreds of available skins, you can tailor your software to your exact needs. VirtualDJ can also record your audio or video mixes, broadcast your own radio station on the Internet, play karaoke, connect with more than 50 DJ controllers natively and many more through downloadable definitions. It can also be controlled by timecode records or CDs, using regular turntables or CD players.
What's new in this version: Version 6.0.7 optimizes video engine, extends native controller support list.
More Products to Consider
- Convert CDs to MP3, WMA, WAV, OGG, FLAC formats, convert audio ...
- Create drum or audio loops and play sample files and MIDI instr...
- Cut desired parts from your MP3 files.
- Record, edit, convert, analyze, and restore sound files.
- Mix, scratch, and remix MP3 or music videos live.
- Play video and audio files, convert to other file formats, burn...
- Create, edit, burn, mount, and encrypt CD, DVD, and BD image fi...
- Convert DVD movies to all the popular video or audio formats wi...
- Rip audio CDs, convert music, and burn discs easily.
- Get fast and flexible digital-media playback with access to sma...
- Convert text into a WAV, MP3, OGG, or WMA audio files.
- Edit your digital audio files on your Windows PC.
- Convert M4A/AAC into MP3/WAV format.
- Convert text into a WAV, MP3, OGG, or WMA audio files.
- Edit MP3 tags, find covers, and organize your music collection.
- Copy DVD to iPod, iPhone, 3GP, PSP, Zune, HD TV, AVI, Divx, Xvi...
- Tag and organize your MP3 music collection, get cover arts, lyr...
- Record any PC sound or your voice into a music file.
- Track your DVD collection and keep up-to-date.
- Run all your Karaoke Shows from your fully touch screen PC.
- Manage your music and movie libraries on your PC, iPod or iPhon...
This download is served from an external site
closeNOTICE: This link will open a connection to a third-party site. CNET cannot ensure the security of software that is hosted on external sites.
Sponsored Products - Run a virtual mixing console for MP3, WAV, and Karaoke (MP3+G) ...
- Batch convert your audio files from one format to another.
- Convert MP3 audio files to WAV, M4A, AIFF, FLAC, AAC, WMA, OGG,...
All versions:
4.2 starsout of 1,088 votes
Current version:
4.5 starsout of 6 votes
My rating:
Write review
Results 1-6 of 6
"Its good software for dj"
Version: Virtual DJ 6.0.7
Easy to use interface and simple
"Perfect simple bit rate control"
Version: Virtual DJ 6.0.7
Great piece of technology.
No cons so far!
"a good hot dj"
Version: Virtual DJ 6.0.7
sounds great
none that I know of
so hot it just rocks for you
"A SWEET program"
Version: Virtual DJ 6.0.7
Fast, brilliant, easy-to-use!
simple and good
"it is very good!"
Version: Virtual DJ 6.0.7
it is very good!
it is very good!
"So cool software"
Version: Virtual DJ 6.0.7
A cool interface, tack and show cool effects
I think nothing.
I like it.
Results 1-6 of 6
Add Your Review
Submit your reply
E-mail this review
Report offensive content
Previous Versions:


text:
No salaries found in Australia - showing BioDefense Salaries in US
7 employee salaries (for 5 job titles)Salaries in USD | Avg. Salary | $50k $100k $150k |
3 BioDefense Salaries in US | $49,833 | |
1 BioDefense Salary in US | n/a | |
1 BioDefense Salary in US | n/a | |
International Business Manager - Hourly 1 BioDefense Salary in US | n/a | |
Biologist At the Department of Engineering 1 BioDefense Salary in US | n/a | |
Salaries in USD | $50k $100k $150k |
Check out the latest BioDefense Jobs & Careers
Pros: Good hands on experience. It is a small company that puts a lot of weight and responsibility on your shoulders. – Full Review
Copyright © 2008–2014, Glassdoor. All Rights Reserved. Your use of this service is subject to our Terms of Use and Privacy & Cookies Policy. Glassdoor ® is a registered trademark of Glassdoor, Inc.
Simply post an anonymous salary for a current or former employer. Your post is anonymous – and if you're worried that someone will be able to identify your salary, you can even post without telling us your employer's name (and it will not be displayed on the site). Learn More.
No thanks – I'll just look around
We do not post on Facebook
We do not post on Facebook


text:
Reviews of Latest Nikon Products, 200 - 500 Pounds
Your Selections
Refine Your Results
CNET UK > Reviews > Cameras and Camcorders > Compact Digital Cameras
Nikon Coolpix P6000 review
Nikon's 13.5-megapixel P6000 looks so good on paper you might wonder whether you need a digital SLR at all. Its sensor matches the pixel count of any low-medium range dSLR, its 4x zoom is more than the average kit lens, it shoots raw files, has a full set of exposure modes and there's vibration reduction too Read more
20 November 2008 by Rod Lawton
CNET UK > Reviews > Cameras and Camcorders > Compact Digital Cameras
Nikon Coolpix S610 review
It's hard to stand out from the crowd, especially since it's become easier to pack gadgets full of features these days. The compact Nikon Coolpix S610 is no exception with a 10-megapixel sensor, image stabilisation, a 4x wideangle zoom, face, smile and blink detection and a nifty automatic scene mode selection Read more
19 September 2008 by Rod Lawton


text:
<storage> (AtFS) The basis of the Shape_VC toolkit.
Cooperative work within projects is supported by a status model controlling visibility of version objects, locking, and "long transactions" for synchronising concurrent updates. The concept of object attributes provides a basis for storing management information with versions and passing this information between individual tools. This mechanism is useful for building integrated environments from a set of unrelated tools.
Last updated: 2000-02-24
Try this search on Wikipedia, OneLook, Google
Nearby terms: atto- « attoparsec « attribute « Attributed File System » Attribute Translation System » ATX » au


text:
iPhone: Troubleshooting a cellular data connection
This article will help you troubleshoot the following cellular data issues on your iPhone:
- No connection over cellular network, but works over Wi-Fi
- Unable to load pages in Safari
- Unable to use email over cellular
- Slow data connection over cellular
- Intermittent cellular data connection
- Unable to join 3G/4G/LTE network
- "Unable to activate cellular data connection" alert message
Follow the instructions below for assistance with troubleshooting cellular data issues on your iPhone. After performing each step, please test to see if the issue is resolved.
- Toggle airplane mode: Tap Settings, turn airplane mode on, wait three seconds, and then turn off again.
- Restart your iPhone.
- Ensure that your software is up to date:
- Check for a Carrier Settings Update. Tap Settings > General > About.
- Check for an iOS Software Update. Tap Settings > General > Software Update.
Note: Some updates may require a Wi-Fi connection.
- Remove the SIM Card and reinsert it. Allow the iPhone to acquire the network again.
- If your SIM card has SIM PIN enabled, try toggling it off: Tap Settings > Phone > SIM PIN.
- Try another location. If a different location works, but the original location still does not, contact your carrier to report the issue.
- Reset network settings: Tap Settings > General > Reset > Reset Network Settings.
- Restore the iPhone as new.
- Contact your carrier to:
- Verify that the iPhone is properly set up on the account with the appropriate, current data plan.
- Verify that there are no account-related blocks.
- Find out if there are specific error messages in the carrier logs that could help determine why the issue is occurring.
If none of the above steps resolves the issue, contact your carrier, make an appointment at an Apple Retail Store, or contact AppleCare to troubleshoot further.
Additional Information
Note: If you are traveling internationally, you may need to turn data roaming on: Tap Settings > Cellular. Check with your carrier first to understand the cost of international data roaming. Also, see this article.
Last Modified: Sep 19, 2013
Start a Discussion
in Apple Support Communities


text:
Koko Bean prides themselves on being sweatshop-free and extensively tested for the highest safety standards. And one test on your little trendsetter will show they're above and beyond the fashion standard too. Koko Bean's funky animal prints, fluffy ruffles and adorable accessories will instantly brighten up any little darling's day.
Fabulous pick! Share your favorites and earn zulily credit. see detailsconnect


text:
this is a discussion within the Saints Community Forum; NEW ORLEANS Drew Brees and the New Orleans Saints are pouring on the points, racking up the wins and rewriting the record books nearly every time they play. Things sure are rollin on the river. Brees led an unstoppable ...
LinkBack | Thread Tools | Display Modes |
(0 votes - average)
NEW ORLEANS Drew Brees and the New Orleans Saints are pouring on the points, racking up the wins and rewriting the record books nearly every time they play.
Things sure are rollin on the river. Brees led an unstoppable offense by throwing for 466 yards and three touchdowns, and New Orleans dominated the second half for a 45-28 NFC wild-card victory over the Detroit Lions on Saturday night. New Orleans broke the postseason mark for total yards with 626, beating the record set 49 years ago. We were pulling out all the stops, Brees said. We play aggressive. Were not going to apologize for that. That gives guys in the huddle a lot of confidence. Were not going to pull the reins back. Its pedal to the medal. Brees hit on 33-of-43 passes while throwing for the most yards in a regulation playoff game. He highlighted his night with three completions of at least 40 yards. We just focus on winning. Were not focused on yards and records, Saints coach Sean Payton said. Im serious when I say that. As usual, the quarterback had plenty of help from an offense that set an NFL record for yards from scrimmage this season (7,474), outgaining Detroit on the ground 167 yards to 32. The Saints (14-3) will travel to San Francisco (13-3) for next Saturdays second-round game. Full article. âAggressiveâ Saints rewrite record book | New Orleans gets a playoff-record 626 yards of total offense in a 45-28 win over Detroit |
Views: 277
Latest Blogs | |
Saints Free Agency 2014 Last Blog: 03-11-2014 By: SmashMouth
Sanity Zone 2-24-2014 The $500 Millon Man Last Blog: 02-24-2014 By: xan
Sanity Zone 2-1-2014 Is New York Shining a Light on the Obvious? Last Blog: 02-01-2014 By: xan |
Thread Tools | |
Display Modes | |
LinkBacks (?)
LinkBack to this Thread: http://blackandgold.com/saints/40029-aggressive-saints-rewrite-record-book.html
Posted By | For | Type | Date | Hits |
Aggressive Saints rewrite record book | This thread | Refback | 01-08-2012 05:23 AM | 3 |


text:
Striped Suspenders
$ 88.00
Striped Suspenders
$ 88.00
Rated 3.8 out of 5 by 4
Rated 2 out of 5 by CKFJr Braces have declined in quality
Thew quality of the elastic is very thin--it seems far too expensive for the quality
June 23, 2010
Rated 4 out of 5 by Mxxtra Braces (suspenders)
There are only a few vendors who still stock braces and I was lucky enough to find them at Brooks Brothers. I have had my eye on these braces for a while after reading a few negitive reviews I was hesitant to buy based on comments. However, I have been pleasently surprised but I have only worn these braces 3 times so we will see in 6 months.
August 17, 2011
Rated 4 out of 5 by DigitalPublisher Braces are fine, I wish there was more adjustment
The braces are typical Brooks Brothers quality, but I wish there was more adjustment for tall people like myself.
October 26, 2011
1-4 of 4
Questions & Answers
Ask your questions. Share your answers.
what color is the metal hardware on these? gold toned or silver toned? does it vary by color combo ordered? also, do any of the solid color braces come with silver toned hardware?
2 years, 2 months ago
McAllen, TX
Hello David L,The hardware is silver toned.
Thank you for contacting us.
Have a great day.
2 years, 2 months ago
Hi, curious about sizing and whether to go with this standard brace or the extra long variety. My business shirts are 42-87cm. Bear in mind, I have a broad frame but am not that tall/long (i.e. much of my shirt is tucked in). As such, would you recommend this standard size or the longer variety?
Additionally, if I am not happy about size, am I able to return (and will that incur charges)? Please note I am in Australia.
Love your stuff by the way!
Additionally, if I am not happy about size, am I able to return (and will that incur charges)? Please note I am in Australia.
Love your stuff by the way!
9 months ago
Why thank you sir. Based on the measurements you provided, the regular braces should work.Regrettably, while you may return of course, you will incur shipping charges. If you do need to return for any reason, please contact customer service via email (a link can be found at the bottom of our site) and reference this post. We're certain we can sort something out.
8 months ago
New York, NY, USA
1 of 1
1 of 1