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Get to know the everyday people who share their personal vacation planning advice and their Disney Parks experiences.
About Me: I grew up on the South Eastern Coast, just 5 hours from Orlando, so Walt Disney World visits were commonplace for milestones, holidays, special events, and "just because!" I now live in Northern California and call Disneyland my second home, visiting every chance I get. Even though living in California affords me the luxury of visiting Disneyland quite frequently, my family still makes the cross-country trek to Walt Disney World several times a year, which makes me somewhat of a coast-to-coast Disney expert! I believe Disneyland is the ultimate vacation destination and when road-trip time rolls around, it's a no-brainer...I'm going to Disneyland! Over the past decade, I have worn many "ears." After spending 5 years in the fashion industry, I switched gears to work side by side with my husband in our restaurant and have most recently taken my DREAM job as a stay at home mommy...which, by the way gives me plenty of time to help YOU plan your next Disneyland vacation.
About My Family: Disney is truly responsible for writing my fairy tale. My husband and I met at Walt Disney World in 2000 and are living happily ever after as parents to a beautiful princess. We believe Disney is in our genes and we're convinced we've passed this magical DNA on to our daughter! We are jet-setters and LOVE to travel, especially to Walt Disney World and Disneyland and like to joke that our Disney bags are always packed and ready for the next adventure! Because we visit Disney Parks so frequently, we became the proud holders of Disney Premier Passports which gives us annual admission to both Walt Disney World and Disneyland. My husband and I love visiting the parks at Disneyland, but we also love to bask in the multitude of luxurious amenities including Deluxe Resorts, Signature Dining, boutique shopping, and renowned spas. Self-proclaimed "Disney foodies" we have eaten at nearly every Signature restaurant from Orlando to Anaheim!
About My Disney Experience: I have been to Disney under many unique circumstances and on almost every imaginable budget. When it comes to experiencing all Disney has to offer, there's not much my family hasn't done. We have visited the resorts, just the 3 of us, and with extended family. We have partied the day away for children's birthdays, and we have had romantic anniversary dinners at Napa Rose. We have visited in observance of strict planning itineraries, but also on spur of the moment with no plan at all! Throughout all of these magical journeys, I have taken notes every step of the way! I believe personal experiences play a huge role in successful Disneyland trip planning and I'm ready to put my knowledge to work for YOU! Once you experience Disneyland the way I have, you'll be a believer, and you'll keep coming back!
How does the kid share work on the rides, I have a 8 year old daughter that does not want to go on Space Mountain but my 10 year old son does and in fact both my husband and I would like to go on too. Do we wait in the regular line?
What is the safest and most convenient way to carry room key, tickets, ID, etc. to the parks? I thought about getting a lanyard with ID holder to wear around our necks. Do they sell Disney ones at the parks?
Does big river grille and brewing works accept reservations on saturday nights? And does it accept the dining plan?
We have one dining credit left. 3 kids 3,6,8. 3 adults. I would like a nice restaurant, dinner March 7, 2012 with fireworks. Outside of parks. Am I asking too much? :)
Son (4), DH,and I will be arriving WDW around 2/13 for 2 nts. Looking 4 best delx or mod resort. Is the GF worth $if not any recommendations? Son loves MM clubhouse show, do the parks have a clubhouse ride? What is the best place for character dining w/MM?


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Congrats to Brad Cooper who won our 14th Anniversary drawing! Brad and a guest will enjoy free racing for a month at Traxx. Thank you to everyone who entered our drawing and helped us celebrate 14 years of fun!
Read MoreTraxx Gives You the Best Value!
Traxx has been the Northwest's original karting facility for over 14 years and we still give you the best value for your karting experience! TRAXX 9 min. race sessions = 15-20 laps Use of Helmets, Helmet Liners, Race Suits, & Gloves included in your race fee Karts are always unlocked to full speed Accommodates kids as young as 3 years old Features the only indoor/outdoor track in the...
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Join Us for our 2nd Annual "Race Against Hunger" Food Drive and our "Toys for Tots" Toy Drive! Help out our local Mukilteo Food Bank & Toys for Tots during this holiday season…Bring in 3 items from the list below or a new, unwrapped toy and receive 20% off your racing that day! Items currently needed at the food bank include: Baby Diapers, Food, Formula and...
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Utah Impeachment Authorization, Amendment 1 (2004)
From Ballotpedia
The Utah Impeachment Amendment, also known as "Constitutional Amendment 1", appeared on the November 2, 2004 statewide ballot in Utah as a legislatively-referred constitutional amendment, where it was approved.[1]
Election results
Utah Constitutional Amendment 1 (2004) | ||||
Result | Votes | Percentage | ||
Yes | 584,661 | 69.28% | ||
No | 259,222 | 30.72% |
Election Results via: The Utah Lieutenant Governor
Text of measure
The language on the ballot said:
Shall the Utah Constitution be amended to: (1) explicitly authorize the Utah House of Representatives to convene for the purpose of impeachment if two-thirds of the representatives are in favor of convening; (2) require the Utah Senate to convene for a trial of impeachment if the House of Representatives has voted to impeach; (3) allow the same amount of legislative compensation per day during an impeachment session as is allowed during an annual general session; and (4) delete an outdated reference to justices of the peace in an impeachment provision?
See also
External links


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Mary Ruth Hall, 51, of Martinsburg, W.Va., died Tuesday, Jan. 22, 2013, at home. Family will receive friends from 7 to 9 p.m. Monday at Brown Funeral Home. Services will be held at 11 a.m. Tuesday at the funeral home. Burial will be in Rosedale Cemetery. Arrangements by Brown Funeral Home.
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Australians might soon be expected to tip as frequently and generously as Americans, new research warns.
Distinguished Australian historian Professor Geoffrey Blainey will be awarded the University of Melbourne's inaugural Tucker Medal, in recognition of his substantial contributions to the University, the Faculty of Arts and to public life.
Professor Marcia Langton says while Native Title agreements have created wealth for Aboriginal communities, government restrictions on trust-funds are holding back Aboriginal business enterprise and the associated long-term benefits for communities.
Dr David Malet says it's possible that the attack in Kenya is a sign of weakness, showing that al-Shabaab is unable to fight for control in Somalia. However, he says it could also mean that the group is gaining more strength.
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The Commercial Alliance Las Vegas (CALV) has announced its new officers and directors for 2014, with longtime member and commercial real estate executive Hayim Mizrachi serving as president of the commercial real estate organization starting Jan. 1. Mizrachi, who is president and a principal of the MDL Group commercial real estate firm in Las Vegas,… [More...]
CALV names Soozi Jones Walker member of the year
The Commercial Alliance Las Vegas has named longtime local real estate professional Soozi Jones Walker its CALV Member of the Year for 2013. CALV President Tedd Rosenstein presented the award to Walker on Sept. 20, during CALV's eighth annual Commercial Alliance Educational Symposium at the Gold Coast hotel-casino. It was the second industry award recently… [More...]
Las Vegas Office Space Lease on Horizon Ridge Parkway
Soozi Jones Walker, CCIM, SIOR and Bobbi Miracle, CCIM of Commercial Executives Real Estate Services recently represented the Horizon Ridge Professional Center, Inc. a Nevada Corporation in the leasing of 1,560 +/- SF of office space located at 2298 Horizon Ridge Parkway Suite 213, Henderson, NV to Margaret Johansen and Katy Steinkamp. The lease is… [More...]
Office Space Lease in Las Vegas
Soozi Jones Walker, CCIM, SIOR and Bobbi Miracle, CCIM of Commercial Executives Real Estate Services recently represented Beltway One Development Group LLC., a Nevada Limited Liability Company in the leasing of 7,719 +/- SF of office space located at 9121 W. Russell Road Suites 110 & 118, Las Vegas, NV to Transitional Hospitals Corporation of… [More...]


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UCCS makes point in snapping losing streak
DENVER -- Coming off its first back-to-back 50 percent shooting games in at least eight seasons, the University of Colorado at Colorado Springs' offense shifted hard into reverse Saturday, making just 22.5 percent of its attempts in a 68-47 defeat at the hands of the No. 8 Concordia-St. Paul Golden Bears at the Auraria Events Center.
The Mountain Lions, who shot 53.3 percent Friday against Newman and 54.9 percent Dec. 14 against Western State, acted as if the rim was just a rumor Saturday. UCCS made just four of its 30 first half attempts to go into the intermission trailing 33-12.
"We came out very tight because of their big presence," said UCCS coach Jessika Caldwell. "They forced us to shoot quickly and without rhythm."
The game was UCCS' second at the Comfort Inn Christmas Classic women's basketball tournament. The loss dropped the Mountain Lions to 5-8 for the season and 5-2 at neutral sites.
Emily Jenkins led UCCS with 13 points, while Tonya Tripp and Whitney Knobbe added seven each. Tripp grabbed a team-high eight rebounds.
Katie LaViolette led Concordia-St. Paul (12-0) with 13 points and 12 assists.
The Mountain Lions' defense was good enough that anything short of the disastrous shooting performance they got would have kept them in the game. Post players Tripp, Nancy Hoist, Alex Pitts and Mallory Lowe limited Bears All-American candidate Amanda Behnke to six points, well below he 18.7-point average to date.
"We did everything defensively that we wanted to do," said Caldwell. "If we could have scored, it could have been different.
"We need to return to that 50 percent feeling."
They'll have their chance to do just that this weekend when UCCS returns to Rocky Mountain Athletic Conference play. The Mountain Lions will host New Mexico Highlands on Friday and Western New Mexico on Saturday.
UCCS Players/Staff Featured | ||||
Emily Jenkins | 22 | F | So. | |
Emily Jenkins | 22 | F | So. | |
Emily Jenkins | 33 | F | Jr. | |
Emily Jenkins | 33 | F | Sr. | |
Whitney Knobbe | 24 | G | ||
Whitney Knobbe | 24 | G | ||
Nancy Hoist | 40 | F | ||
Nancy Hoist | 40 | F | ||
Nancy Hoist | 40 | F | ||
Tonya Tripp | 43 | C | ||
Tonya Tripp | 43 | C | Sr. | |
Mallory Lowe | 34 | C/F | ||
Mallory Lowe | 34 | C/F | ||
Mallory Lowe | 34 | C/F |
Additional News Stories | |||
June 11, 2008 | Caldwell sees a little of herself in young UCCS campers | There may be a few future Jessika Caldwells running around at the University of Colorado at Colorado Springs Recreation Center this week.Caldwell, the coach of the UCCS women's basketball team, is currently holding the first of her annual summer camps. Thirty campers, ranging in age from 6- to 10-years old, are honing their skills under the tutelage of Caldwell and seven other coaches, some of whom are current Mountain Lions basketball players. The camp runs from June 9-12 and goes from 9 a.m. to noon each day. | |
May 28, 2008 | Mountain Lions add four more to 2008-09 women's basketball squad | University of Colorado at Colorado Springs women's basketball coach Jessika Caldwell announced Wednesday that she had signed four players to National Letters of Intent. | |
February 27, 2008 | Tripp named second-team all-RMAC. | University of Colorado at Colorado Springs center Tonya Tripp was named second-team all-Rocky Mountain Athletic Conference team for the East division, the conference announced Wednesday. | |
February 23, 2008 | Season ends with loss to Nebraska-Kearney | KEARNEY, Neb. -- Four Mountain Lions scored in double figures but the University of Colorado at Colorado Springs were nonetheless beaten Saturday, 82-67 by the Nebraska-Kearney Lopers at the health and Sports Center. | |
February 21, 2008 | Tripp's 28 not enough as Mountain Lions fall to Chadron State | CHADRON, Neb. -- Tonya Tripp had 28 points and 12 rebounds and Janean Jubic had eight assists but the University of Colorado at Colorado Springs nonetheless fell 86-81 to the Chadron State Eagles Thursday evening at Armstrong Gym. |


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Make no mistake about it, Microsoft will get back on its feet in 2011. In order for that to happen, however, the company needs to do what Apple Kool–Aid drinkers do so well, which is blow their horn.
After all, Apple people have been nimble and correct more than anyone in a fickle consumer marketplace.
Take iPhone- and iPad-totting executives and middle managers who brought Apple's iDevices a much-needed business credibility more than a fully-blown advertising assault could have ever achieved.
While certainly not taking tips from the Jobs' playbook, 2011 will be the year that Ballmer finally transitions the Redmond-based company from a software behemoth to a versatile, efficient and effective service organization. Google will continue to progress only in the area they have historically carved out for themselves, which is click-thru sales.
Microsoft should certainly be praised for building the physical and fiscal foundation for organizations of all types and coupling that with cloud services and support.
Of course, the company also faces big challenges as the likes of IBM, Amazon, EMC and others increase competition in this space.
At the end of the day, Microsoft's strategy should return them to the good graces of the world's economic engine and possibly the shareholder community.
When it comes to businesses in all of the computer, consumer electronics and communications sectors, they will move forward cautiously. Both business and individual consumer optimism and investment should rise slowly and steadily in 2011, which in itself is an awesome news.
But don't expect this to have a big impact on your life in the upcoming year because it is going to take several years before we lift our heads from the proverbial grindstone and see the world through rose colored glasses again.
And there you have it, this is what any self-respecting geek should expect from 2011. Disappointed? Don't be. Can't be any worse than 2010.
And there you have it. Coupled with Part One, this piece wraps up our little two-part forecast of the technological trends to look for in 2011. Hope you enjoyed the analysis and remember where you read it first. Meet us in comments.
Thanks for reading BSN*


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There was no parade. No streamers. No speech. Not even a phone call to the press as Scott McInnis formally launched his campaign for governor Tuesday by filing paperwork with Colorado's secretary of state. McInnis, a Republican and former congressman, was instead in New York and unavailable for comment, leaving his spokesman to explain some kind of campaign hoopla would come at a later time, reports The Associated Press [2]. Significantly, it was the blogs, snarky as they can be, that had the most to say about McInnis, whose muted announcement came in the wake of allegations by Colorado Ethics Watch [3] that he was campaigning illegally. The Colorado Independent [4] wonders if McInnis can even get past Senate Minority Leader Josh Penry, who hasn't even announced whether he'll run, let alone Governor Bill Ritter. ColoradoPols [5] ponders if it was the ethics concerns that led McInnis to opt out on the chance to "whoop it up as much as possible," as "smart politicians" are prone to do. The conservative Face the State [6], meanwhile, characterized Colorado Ethics Watch's allegations as the group's "latest attack on a Republican candidate." The Denver Post [7] notes that for weeks critics have hounded McInnis, arguing that he has campaigned without announcing his candidacy and should disclose his finances.
[1] http://www.5280.com/tag/authors/michael-de-yoanna
[2] http://cl.exct.net/?qs=3ed1a07cc26edac40833be84b379833c08943f09b4f449a9cccbee2094932d73
[3] http://cl.exct.net/?qs=3ed1a07cc26edac4d0ec4cbe4d90e675c3aec3b8eace80b61a1ac00ed3efd1b4
[4] http://cl.exct.net/?qs=f82ef684ed9402b8e0848e28c70d74e179899ebbb09fc27e96f0d359f0ab5cb8
[5] http://cl.exct.net/?qs=f82ef684ed9402b85e613d766e2aa0976abec4bffe96ba17b940c2954d3cb306
[6] http://cl.exct.net/?qs=c2ff5c10084e91c357b911e45689e275b2e7853f74ac6c1315d93f2bf5864cc9
[7] http://cl.exct.net/?qs=01d81eb4039c117a72f2a2cc87c64e9ea6a135f469f0cc7b897422ec6af5b935


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Good morning friends . . .
A problem with Doowee's idea is that Doowee looks too heavy to stand on Wizer's shoulders.
Maybe . . . let's see what happens this week and leave it at that, Oopsters.
Alternate Alley Oop Chapter 19 "The Savage Land of Promise"(3) 5/10/2013 Monday
Panel One
It was a shock when all those men and women of the TexComm security service came through the wormhole about a day after all the others. Somehow those super intelligent creatures of Earth 2 can activate their equipment over millions of miles away on the other side of Sol.
Panel Two
They were tested and no anomalies could be found in their psychology or physically. In fact they had the highest readings ever for human norms. Whatever happened there changed them on a cellular level. still waiting on the fNMRIs on their brain function to come back. How the other scientists argued with the military and the corporation TexComm itself. In the end the TexComm soldiers got their way and they were put on duty for the foot hold on yet another world. One without super-intelligent cryptid dinosaurs but much more life, and much more aggressive life than on Earth 1 and 2.
functioning Nuclear Magnetic Resonance Imaging. -
Now we have a larger version of the last two panels from yesterday. Same subversion being hatched by evil minds.
There' that PC word again…
"crazy person".
"crazy man" is correct, NOT person…
People , back then, in cave man days, would use the non-PC word "man" in preference to "person".
And, another thing, who is the Wizer to criticize the lawyer for wanting to escape from the pit ?? -
There is rather than There…….
We do need an edit and spell check, built in… -
Person is best used when you don't know the gender and since we have two it behooves us to acknowledge it.
So, if one or the other climbs out, how is the other one still in the Pit to get out? And wouldn't the guard or some other person see them?
The qalls of The Pit have turned to a glassy substance.
If I was Wizer I wouldn't trust him. If Doowee was sincere, he would suggest the more obvious course of action, ie. Wizer should stand on his shoulders instead. Wizer is smaller, older, and weaker.
PC would be person with a mental disorder or a person who is developmentally delayed. The mystery is why is perSON any better than MAN or huMAN? PC is liberal stuff and is to be avoided. You see the PCers would never use the word "crazy".
I'm not politically correct and I'll use "crazy" if the situation fits.
I remember when political correctness burst upon the scene..
The woman had just been granted the right vote..The black had early zero rights;
Person replaced man.
Ms replaced miss or Mrs
person hole cover replaced man hole cove…lol…lol…
As with all things extremism rears its ugly head…
And I am old fashioned.
It will be "man" til 2040…..PC be damned.. -
So they are going to climb out of the pit, huh?
How about "huperson" and "hupersonity?" My favorite is "hyperson."
Or I guess that should be "hypeople" since it's spelled with an e rather than an a.
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Selma in Sandy Eggo wrote:Also, I suspect that the x-ray positions required for knee and hip evaluation are a screening technique. If you can twist yourself into those postures without assistance, you don't need treatment.
I remember twisting my ankle so bad many years ago it requried a trip to the ER.
The person who drove me was assisting me into the entrance of the ER.
There were Nurses, Drs... etc.... empty wheelchairs....
As soon as we walked/limped in.... no-one did anything.. let us go down this
LONG Hallway (about 100 feet) . When we sat down, someone came up to us
and asked do you need a wheelchair?


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isitreal - 10:49 pm on Oct 2, 2004 (gmt 0)
I read this argument about a year ago. It wasn't impressive then, and it's not impressive now.
critter, have you read the original white papers? Give them a read again if it's been a while. They were published not that long before google went fully live, this stuff doesn't get changed yearly. But it does need to get changed. entry. Most likely the URL's identifier is the question mark portion.


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Features a raincover and is equipped with an attachment option for a bicycle pump, bottles and trekking poles.
Main compartment has four pockets and an attachment for LED light. For use with a hydration system. With reflectors.
Dimensions: 144 x 24 x 14 cm. Capacity: 12-litres. Weight: 560g.


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Hope Where there were questions, Jesus came along and answered them— Yes, I love you. Yes, there's hope. Yes, all things are possible in peace, in rest…in Me. —Trieste Van Wyngarden
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Celebrating the awesome Yes of Jesus… and praying you're blessed by His joy and love at Easter and always. All of God's promises have been fulfilled in Christ with a resounding "Yes!" II Corinthians 1:20 NLT
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When Sharing Your Home is an Act of Reckless Optimism
The Saturday morning after Christmas I opened our bedroom door, stepped into the Camp family version of Noah's flood, and screamed. A pipe backed up and dumped my daughter's draining bathwater out through the overflow in the laundry room and water spread into our kitchen, dining room, entry, living room, bedroom, and hallway. The bathrooms […]
You Can Be Certain… Part 2 of 2
God has His eye upon you and you are precious to Him and loved. Since you were precious in My sight, You have been honored, And I have loved you; […]


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I hope soon is days, not weeks! :)
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I hope soon is days, not weeks! :)
Turns out it was just days this time. Thanks for your interest. :)
Already ordered!
Some great stones wt. that DVD.I always use a spray bottle now, don't know how I did wt. out it all those yrs.:sleeping:
You should make this into a digital download :-)
I agree. I live in another country and generally just use my iPad for most media viewing...don't even have a convenient DVD player at the moment (I have one, but it's an old external drive that's not currently hooked up to my computer).
I'm pretty sure I'd buy if it were a downloadable purchase.
I would purchase a digital download as well.


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Summary: "Darkly hilarious...an unexpected bundle of joy."
-O, The Oprah Magazine
Alice Cohen was happy for the first time in years. After a difficult divorce, she had a new love in her life, she was raising a beloved adopted daughter, and her career was blossoming. Then she started experiencing mysterious symptoms. After months of tests, x-rays, and inconclusive diagnoses, Alice underwent a CAT scan that revealed the truth: she was six months ...show more pregnant.
At age forty-four, with no prenatal care and no insurance coverage for a high-risk pregnancy, Alice was besieged by opinions from doctors and friends about what was ethical, what was loving, what was right. With the intimacy of a diary and the suspense of a thriller, What I Thought I Knew is a ruefully funny, wickedly candid tale; a story of hope and renewal that turns all of the "knowns" upside down. ...show less
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- ZNF423 Is Critically Required for Retinoic Acid-Induced Differentiation and Is a Marker of Neuroblas...
ZNF423 Is Critically Required for Retinoic Acid-Induced Differentiation and Is a Marker of Neuroblastoma Outcome
Cancer Cell, Volume 15, Issue 4, 7 April 2009, Pages 328-340
Sidong Huang, Jamila Laoukili, Mirjam T. Epping, Jan Koster, Michael Hölzel, Bart A. Westerman, Wouter Nijkamp, Akiko Hata, Shahab Asgharzadeh, Robert C. Seeger, Rogier Versteeg, Roderick L. Beijersbergen and René Bernards
SummaryRetinoids play key roles in differentiation, growth arrest, and apoptosis and are increasingly being used in the clinic for the treatment of a variety of cancers, including neuroblastoma. Here, using a large-scale RNA interference-based genetic screen, we identify ZNF423 (also known as Ebfaz, OAZ, or Zfp423) as a component critically required for retinoic acid (RA)-induced differentiation. ZNF423 associates with the RARα/RXRα nuclear receptor complex and is essential for transactivation in response to retinoids. Downregulation of ZNF423 expression by RNA interference in neuroblastoma cells results in a growth advantage and resistance to RA-induced differentiation, whereas overexpression of ZNF423 leads to growth inhibition and enhanced differentiation. Finally, we show that low ZNF423 expression is associated with poor disease outcome in neuroblastoma patients.
Summary | Full Text | PDF (1810 kb) - Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate r...
Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate risk neuroblastomas
Cancer Cell, Volume 7, Issue 4, 1 April 2005, Pages 337-350
Miki Ohira, Shigeyuki Oba, Yohko Nakamura, Eriko Isogai, Setsuko Kaneko, Atsuko Nakagawa, Takahiro Hirata, Hiroyuki Kubo, Takeshi Goto, Saichi Yamada, Yasuko Yoshida, Misa Fuchioka, Shin Ishii and Akira Nakagawara
SummaryTo predict the prognosis of neuroblastoma patients and choose a better therapeutic protocol, we developed a cDNA microarray carrying 5340 genes obtained from primary neuroblastomas and examined 136 tumor samples. We made a probabilistic output statistical classifier that provided a high accuracy in prognosis prediction (89% at 5 years) and a highly reliable method to validate it. Kaplan-Meier analysis indicated that the patients in an intermediate group defined by existing markers are divided by microarray into two further groups with 5 year survivals for 36% and 89% of patients (p < 10−4), i.e., with unfavorably and favorably predicted neuroblastomas, respectively. According to these results, we developed a gene subset chip for a clinical tool, for which our classifier exhibited 88% prediction accuracy.
Summary | Full Text | PDF (950 kb) - The ALK Mutation Potentiates the Oncogenic Activity of MYCN in Neuroblastoma
The ALK Mutation Potentiates the Oncogenic Activity of MYCN in Neuroblastoma
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Teeara Berry, William Luther, Namrata Bhatnagar, Yann Jamin, Evon Poon, Takaomi Sanda, Desheng Pei, Bandana Sharma, Winston R. Vetharoy, Albert Hallsworth, Zai Ahmad, Karen Barker, Lisa Moreau, Hannah Webber, Wenchao Wang, Qingsong Liu, Antonio Perez-Atayde, Scott Rodig, Nai-Kong Cheung, Florence Raynaud, Bengt Hallberg, Simon P. Robinson, Nathanael S. Gray, Andrew D.J. Pearson, Suzanne A. Eccles, Louis Chesler and Rani E. George
SummaryThe ALKF1174L mutation is associated with intrinsic and acquired resistance to crizotinib and cosegregates with MYCN in neuroblastoma. In this study, we generated a mouse model overexpressing ALKF1174L in the neural crest. Compared to ALKF1174L and MYCN alone, co-expression of these two oncogenes led to the development of neuroblastomas with earlier onset, higher penetrance, and enhanced lethality. ALKF1174L/MYCN tumors exhibited increased MYCN dosage due to ALKF1174L-induced activation of the PI3K/AKT/mTOR and MAPK pathways, coupled with suppression of MYCN pro-apoptotic effects. Combined treatment with the ATP-competitive mTOR inhibitor Torin2 overcame the resistance of ALKF1174L/MYCN tumors to crizotinib. Our findings demonstrate a pathogenic role for ALKF1174L in neuroblastomas overexpressing MYCN and suggest a strategy for improving targeted therapy for ALK-positive neuroblastoma.
Summary | Full Text | PDF (3115 kb) - …more
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Copyright © 2010 Elsevier Inc. All rights reserved.
Cell, Volume 142, Issue 2, 218-229, 23 July 2010
Add/View Comments (0)NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome
Michael Hölzel1, 6, Sidong Huang1, 6, Jan Koster2, Ingrid Øra2, Arjan Lakeman2, Huib Caron3, Wouter Nijkamp1, Jing Xie5, Tom Callens5, Shahab Asgharzadeh4, Robert C. Seeger4, Ludwine Messiaen5, Rogier Versteeg2 and René Bernards1, ,
1 Divisions of Molecular Carcinogenesis and Molecular Genetics, Center for Biomedical Genetics and Cancer Genomics Center, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
2 Department of Human Genetics, Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
3 Department of Pediatric Oncology, Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
4 Department of Pediatrics, Division of Hematology/Oncology, and Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA 90027, USA
5 Department of Genetics, Medical Genomics Laboratory, University of Alabama at Birmingham, Birmingham, AL 35294, USA
6 These authors contributed equally to this work
Graphical Abstract
► Loss of NF1 blocks retinoic acid (RA) induced differentiation in neuroblastoma ► Loss of NF1 represses the RA receptor coactivator ZNF423 through RAS-MEK signaling ► Mutations and low expression of NF1 occur in primary neuroblastomas ► MEK inhibitors restore the RA response in NF1-deficient neuroblastomas
- PaperClip (2.65 MB)
- Retinoic acid (RA) induces differentiation of neuroblastoma cells in vitro and is used with variable success to treat aggressive forms of this disease. This variability in clinical response to RA is enigmatic, as no mutations in components of the RA signaling cascade have been found. Using a large-scale RNAi genetic screen, we identify crosstalk between the tumor suppressor NF1 and retinoic acid-induced differentiation in neuroblastoma. Loss of NF1 activates RAS-MEK signaling, which in turn represses ZNF423, a critical transcriptional coactivator of the retinoic acid receptors. Neuroblastomas with low levels of both NF1 and ZNF423 have extremely poor outcome. We find NF1 mutations in neuroblastoma cell lines and in primary tumors. Inhibition of MEK signaling downstream of NF1 restores responsiveness to RA, suggesting a therapeutic strategy to overcome RA resistance in NF1-deficient neuroblastomas.


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Baseball isn't a magic trick ... it doesn't get spoiled if you figure out how it works. - gonelong
I'm witchcrafting everybody.
Back in 1988 the A's went out and got Don Baylor whom Sandy Alderson said. "Was obtained as much for his talisman quality as his bat." That was the end of Baylor's career and he was in the World Series each of his last 3 years with 3 different teams.
Just glancing back on the various championship teams the Reds have had, I will say those teams didn't generally have many older players; although I think more players are playing later than in previous times. I'm not certain of that, but I remember a thread here recently on a higher percentage of players playing into their late 30's and early 40's.
I did see that the 1919 Reds had a 35 year old Jake Daubert in his first season with the Reds. In 1922 it appears to me that he broke the club record for most homers in a season (12) and nearly broke the record for triples (he had 22) - not bad for a 38 year old. He finished his career in the 1924 season, falling ill towards its end. He died in October of 1924 following complications in surgery at the age of 40 (my grandfather had the same thing happen some 10 years later). But during his five years with our club, he was a pretty good ballplayer. (It should be noted that 40 back then was like Julio Franco still playing at nearly 50).
I agree 100% that if a team doesn't have the tallent, no amount of Vet Presence will overcome that. I also agree 100% that vet presence and PTGTRW is often code for "this guy is marginal but we have to explain why we traded for him".
However, I think there is definatley a value of having vets around to pass down tips and tricks to help players improve. Why do you think players flock to a Soto or Bench? There's a value to having someone who's been there before to mentor someone who has not. Raw tallent only gets you so far if it isn't focused. The managers/coaches job is to focus that tallent, but there is no one better than a "peer" to go to when you are having problems and help you think about things in a different way.
I'd dissagree that any mix of "elderstatesman" will do. Bonds qualifies, but do you really want him in your clubhouse?
I think the Reds have over used the "vet presence" and PTGTRW bit soooooo much that many here roll their eyes in distain when they hear it. It's a shame because the addition of a vet who can actually contribute on the field, in addition to in the clubhouse is of critical importance, IMO. Young, raw, unfocused tallent isn't the answer to every problem.
Last edited by Ltlabner; 05-02-2007 at 05:08 PM.
a super volcano of ridonkulous suckitude.
I simply don't have access to a "cares about RBI" place in my psyche. There is a "mildly curious about OBI%" alcove just before the acid filled lake guarded by robot snipers with lasers which leads to the "cares about RBI" antechamber though. - Nate
a super volcano of ridonkulous suckitude.
I simply don't have access to a "cares about RBI" place in my psyche. There is a "mildly curious about OBI%" alcove just before the acid filled lake guarded by robot snipers with lasers which leads to the "cares about RBI" antechamber though. - Nate
Say what you will about Barry Bonds, but he seems to be able to carry a baseball club on his back, even if he's lacking in the humanity department.
The disdain comes when PTGTRW doesn't PTGTRW. I've been told guys who can't play SS worth a lick play the game the right way. I've been told pitchers who can't do much more than absorb abuse while they're on the mound play the game right way. I've been told guys who can't hit their way out of a wet paper bag play the game the right way.
Jose Reyes plays the game the right way. Grady Sizemore plays the game the right way.
I've got no problem in using vets to fill holes in accordance with their talents. It's when PTGTRW is used as a blanket protection for an otherwise exceedingly poor decision that fries my bacon.
Baseball isn't a magic trick ... it doesn't get spoiled if you figure out how it works. - gonelong
I'm witchcrafting everybody.
And that's the point. Just like the boy who cried wolf, the Reds cry "vet presence" so much we tend not to believe them any more even when a guy like Conine is signed. And youth isn't the answer every time. A lot of folks wanted Joey Votto on the Opening Day roster but he's barely hitting his weight in LOU. Doesn't mean that he's not a good player but his history has shown he takes a year to adjust to the next level. I don't think anyone is saying youth is the answer every time. But neither is "vet presence". You can't expect to win with a team full of scrappy vets just like you can't expect to win with a team full of raw rookies.
The Rally Onion wants 150 fans before Opening Day.
Eh I don't see it, as much as people talk about Aurilia bashing it's nowhere near the dead horse that people bashing on Dunn is.
Until the 2nd half of last year after the "trade" there was always younger player on the roster people would have rather seen, in 05 it was Lopez and then EE, and again last year it was EE and Deno.
He's gone now so maybe we can all let it go.
Go Gators!


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User Review: GSI Ultralight Soloist Cook System
Price Paid: $30
This is a great cookset. It definitely is not made cheap. The handle snaps in position very well. The lid has a good fit in the pot and bowl/mug.
I use an alcohol can stove and boiling up to 16oz of water is relatively easy. The last time i used this set i cooked one cup of 10 minute rice (3min boiling time and 8min in the pot more or less). Rice was great.
GSI did a great job keeping it cheap but with good quality. The new system comes with a spoon/fork and is Teflon coated. The carrying bag does work as a sink!
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Hi bonavista, thanks for the very nice entry and the ❤!
My best wishes, Reiner
Another beautiful photograph, a single gateway and estreco that have happened in the boat in which he worked, to go to dry dock next to the aquarium.
I like it and wear it with my favorite
Greetings from Spain. José Mª
Beautiful photo of one of the most beautiful places in the city, and a scene that can be seen any day at this time.
I Like
Greetings from Spain. José Mª


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Florida Gators Gear
Florida Gators Mens
Florida Gators Mens Gameday & Tailgate
Florida Gators Mens Gameday & Tailgate Imagine that
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Show everyone that you're the #1 Gators fan while sporting this decorative pin! This pin works great as an accent on a lapel or a hat.
- Lapel pin
- Enameled in vibrant color
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- Approximately 1.5" x .5"
- Officially licensed collegiate product
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Customized items can be personalized with options such as your name, your favorite
number, and/or designs. Some options may be limited by league rules.


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Mar 2, 2011
GENEVA, March 2, 2011 /PRNewswire/ -- NAVTEQ, the leading global provider of maps, traffic and location data enabling navigation, location-based services and mobile advertising around the world is supplying Nissan with a specialized dataset which provides relevant location information, such as location of charging stations, to drivers of the new 100% electric Nissan LEAF. This POI information was collected by NAVTEQ particularly for drivers of electric vehicles.
With first deliveries in Europe due in the first quarter of 2011, the Nissan LEAF includes the Nissan Connect powered by CARWINGS navigation system as standard so drivers will be able to benefit from the EV dedicated NAVTEQ POIs which contain key information for Nissan LEAF owners. In addition to the location of charging stations, the data also features details such as the type (normal or quick) and number of connectors.
"The system provides real-time information to the driver, including the location of the nearest charging station. It also allows the driver to optimize the car's driving range," commented Tom Smith, Nissan LEAF Chief Marketing Manager, Nissan International SA. "This ability to 'read the road ahead', relies on an accurate, precise map. NAVTEQ's unique approach to quality is key to the value of this offering as it helps give drivers the confidence they need when they drive to find EV charging stations."
For accuracy and currency, NAVTEQ is continuously updating the information ready for quarterly delivery to the NISSAN CARWINGS Data Center - a globally common platform providing identical telematics services via mobile network. Nissan has developed a sophisticated IT system for Nissan LEAF which can connect to the NISSAN CARWINGS Data Center to receive dynamic content 24/7.
"Having been at the forefront of technology with our product portfolio for many years, we are delighted to have been able to contribute to the development of Nissan's environmentally friendly car," added Bruno Bourguet, SVP Sales EMEA, NAVTEQ. "This again underscores our commitment to lead in new and fast emerging developments like the Electric Vehicle."
NAVTEQ EV POIs are currently available for Austria, Belgium, Denmark, France, Finland, Germany, Ireland, Italy, Netherlands, Luxembourg, Norway, Portugal, Sweden, Spain and the UK with plans to expand right across Europe.
See the innovative Nissan LEAF Electric Vehicle on the NAVTEQ stand:
NAVTEQ stand 7000, Hall 7
81st International Geneva Motor Show, 1-13 March 2011.
About NAVTEQ
NAVTEQ is the leading global provider of maps, traffic and location data (digital location content) enabling navigation, location-based services and mobile advertising around the world. NAVTEQ was founded in 1985 and now supplies comprehensive digital location content to power automotive navigation systems, portable and wireless devices, Internet-based mapping applications and government and business solutions. The Chicago-based company was founded in 1985 and has more than 5,400 employees located in 214 offices in 49 countries.
NAVTEQ is a trademark in the U.S. and other countries. All rights reserved.
About Nissan
Nissan Motor Co., Ltd., a global leader in the automotive industry, is headquartered in Yokohama, Japan. With more than 150,000 employees worldwide, the Company operates 31 vehicle manufacturing plants, 5 design centers and 24 R&D facilities and offers products and services in more than 190 countries. In addition to a comprehensive range of fuel-efficient and low-emissions vehicles under the Nissan and Infiniti brands, the Company is the innovation leader in the development of affordable, 100% electric, zero-emissions vehicles along with its Alliance partner, Renault. Nissan posted record sales of 4,080,588 units in 2010, an increase of 21.5% compared to previous year.
(Logo: http://photos.prnewswire.com/prnh/20060313/NAVTEQLOGO)
For further information: Please go to: www.press.navteq.com/pressinquiries


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Meet the owner
Last updated 135 days ago
King of Prussia, PA 19468
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2010 RAV4 with 3rd row seating. Seat covers are on all seats. Available weekdays in the King of Prussia area.
Available for hourly rentals M-F 8:30 AM - 4:30 PM
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Keurig Coffee System
I am looking for the best deal on a Keurig system. My wife has asked for one for Christmas. We don't need one with all the bells and whistles and she will probably be the only one using it. I know that Staples has a deal going on where you can combine a 20% off coupon along with receiving a Staples GC. Seems decent, but I want to make sure that there isn't a better deal. Thanks! |
Put "Keurig" in the SEARCH box at the top of the page. Make sure you get the drop down and make sure that only the "Search in Thread" titles is checked. You will get a list of Keurig threads in order of most recent first. hth.
The Staples Information Thread: If you have any questions, please check this thread first as it answers many common questions.
The Staples App Thread: For info on app coupons (5 off 25, 10 off 50, etc.) and how to obtain app coupons, go here. Ink/toner Recycling Primer/FAQ: Information relevant to ink recycling and rewards at Staples and elsewhere. Sebsa: "This coupon stacking art form is becoming less like the Mona Lisa and more like a Picasso." |
Saved a buck or two? Thank the OP by repping if you like the post or was helped out You can always Thumb up the deal and rep those that helped you. Found a sour deal or bad deal Click on the Thumbs Down. What would my life and wallet be without slickdeals?
TDMVP73= MM FAR Discombobulated= Super Mario NewEgg Warrior. GoodDay= Twice as nice gotta hear it thrice. CaliStyle= all over the place. EVO-IC= Android apk rom pwner. dj-3xclusive= fleBay daily-deal killer. yuugotserved= got served slickness. |
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Sales used to be relatively predictable. A popular 1975 book could say with assurance that luggage went on sale in March and the best month to buy a baby car... Read More
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Alice's Day
Saturday 6 July 2013
Delightfully scroobious, or uffishly vorpal? 'Nonsense' was the theme of this year's Alice's Day, which celebrates the first telling of Lewis Carroll's Alice's Adventures in Wonderland, on the River Thames in Oxford.
More than 20 of Oxford's most beautiful and historic locations took part for a day of topsy turvy fun in wonderful summer weather.
Restaurants and cafes also joined in with Alice-themed refreshments.
Download the Alice's Day 2013 map and guide
Next year's event takes place on Saturday 5 July 2014.
For a round-up of the events of 2013, click here.
scroobius stuff
"If I had a world of my own," said Alice, "everything would be nonsense!"
2013 marked the sixth Alice's Day, which is co-ordinated each year by The Story Museum.
bird's eye view of 2013 events
Alice's Shop
The real Alice's favourite sweet shop. More info.
Ashmolean Museum
Nutty but nice crafts to try, Alice and Rabbit trails, and tea on the rooftop with the Mad Hatter. More info.
Blackwell's Bookshop
Family fun day with giant nonsense poem, balloons, face painting, crafts - and a crazy nonsense poetry competition to win £200 for your school. More info.
Bodleian Library
Surreality with Salvador Dali, plus storytelling. More info.
Broken Spoke at The Story Museum
Fix your bike, decorate your helmet to become an animal, and join in the Cowley Road Carnival on 7 July. More info.
Central Library
Nonsense fun with author Diana Moore, a free quiz, face-painting and Alice books to borrow. More info.
Christ Church Library
Exhibition of nonsense poetry and art by local schoolchildren, and of Lewis Carroll's nonsense work. More info.
Museum of the History of Science
Discover early photography, explore the Museum, and help animate Alice's adventures. More info.
Oxford Town Hall and Museum of Oxford
Nonsensical stories, face painting, Alice Juke Box and a life size walking, talking Dodo. Follow Alice into Townhall Wonderland and create topsy-turvy artwork. More info.
Old Fire Station
Find out more about nonsense literature, Lewis Carroll's mastery of the genre and how others in Oxford and beyond have interpreted it. A morning of free talks, from 10.15-12.30. Plus unlock your inner Alice with a family workshop. More info.
Oxford Castle Quarter: Oxford Castle Unlocked
A "mound" of nonsense: picnic and riddles on Castle Mound. More info.
Oxford Castle Quarter: O3 Gallery
Nonsense exhibition. More info.
Pitt Rivers Museum
Flibbity flub: a world where everything is what it isn't. Drop in activity. More info.
The Story Museum
Performances from Teatro Vivo in all corners of the Story Museum's atmospheric building. Storytelling, Surrealist games, printing, cycle workshop. Expect the unexpected. More info.
University of Oxford Botanic Garden
Alice Through The Pinhole exhibition and family picnic afternoon. More info.
University of Oxford Shop
Dodos galore, a special window display, free quiz and special offers on dodo products!
Visitor Information Centre
Information and a free Alice tour. More info.
Whittard of Chelsea, High St
An all-day tea party, with all your favourite characters.
Pilgrimage walk
Follow the route of the famous rowing trip, during which the Alice story was first told, with author and Alice expert Mark Davies. More info.
Alicean eats
Alice-themed places to eat and drink on the day. Take a look.
other partners
- Lewis Carroll Society
- Oxford City Council
- Oxfordshire County Council
- Oxford Inspires
- The Oxfordshire Reading Campaign
why not make a weekend of it?
Alice's Day takes place on the same weekend as the Cowley Road Carnival. Why not make the most of Oxford's festival weekend and enjoy both days. Find out more about accommodation and restaurants at Visit Oxfordshire and the Oxford City Guide.
Alice updates
Follow us on Twitter and Facebook
Subscribe to our newsletter. Picture gallery/round up coming soon.
about Alice's Day
One golden afternoon on 4 July 1862, Charles Dodgson, an Oxford don, took Alice Liddell and her sisters on a boating picnic up the River Thames from Folly Bridge in Oxford. To amuse the children he told them a story about a little girl, sitting bored by a riverbank, who finds herself tumbling down a rabbit hole into a topsy-turvy world called Wonderland. The story so delighted the 10-year-old Alice that she begged him to write it down – the result was Alice's Adventures in Wonderland, published in 1865 under the pen name Lewis Carroll. It became one of the best-loved children's books ever written.
To celebrate that first telling, Oxford turns into Wonderland for one magical day every year.
mailing list
If you would like to receive updates on Alice's Day, and other Story Museum activity, just e-mail us with the heading: SUBSCRIBE.


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Nov 9, 2012 at 11:30am
timestretchinghi what's the best way to timestretch an audio source as it is made? it'll be from a synth to max/msp via firewire. thanks? |
Nov 9, 2012 at 7:45pm
Hi https://www.youtube.com/user/ronnie9253 Brendan |
Nov 9, 2012 at 8:11pm
And for more advanced live processing, search for J F Charles and spectral processing |
Nov 9, 2012 at 8:33pm
and i could bang so that it jumps to and starts to stretch what i'm currently playing? just checking that i understand you… |
Nov 9, 2012 at 9:03pm
Yes, but not what you're "currently" playing, only what was recently played. Depending on the setup, you could timestretch as recently as maybe 200ms, but this isn't set in stone. How instant is instant?? |
Nov 10, 2012 at 12:02am
ah, yes. |
You must be logged in to reply to this topic.


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Google's next search foe: Facebook
June 25, 2010: 9:47 AM ETFacebook's search engine is now venturing beyond the walled gardens of Facebook.com to the greater web. Will its user-generated results give it an advantage over Google?
AllFacebook is reporting that Facebook is now displaying some 'outside' webpages with in its Facebook search results. For instance, if you Search for the Annapolis Marriott hotel in Facebook, one of the results is the TripAdvisor page which has been favorited by five 'Facebookers.'
To make matters worse for Google (GOOG), Facebook uses Microsoft's (MSFT) Bing Search to place Web results at the bottom of the Facebook search results.
Also, it appears that Facebook is only including results with special codes embedded into the Web Page, which Trip Advisor has included. That doesn't mean Facebook won't be crawling the greater web, for results.
Will Facebook's Semantic Search Engine, which uses user popularity as a measure of website quality and keyword relevance be enough to best Google? Will "link baiting" give rise to "like baiting"?
Facebook 'likes' could become the new PageRank if Facebook search becomes more popular. That could also mean an army of offshore faux Facebook users liking Viagra pages.
If this kind of search becomes useful and therefore more utilized, is Google's search dominance in jeopardy? Facebook does have some mind-bendingly huge numbers of users and growth. It remains to be seen how much better this feature becomes.
If Facebook's search can garner better results than Google, then there is some trouble ahead for Mountain View.


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Bombardier Inc. (BBD/B) and Siemens AG (SIE) are among five companies shortlisted for a 1.5 billion-ringgit ($500 million) contract to supply locomotives for the first part of a Kuala Lumpur rail network.
The winner of the deal will be announced by the middle of the year, Azhar Abdul Hamid, chief executive officer of operator Mass Rapid Transit Corp., said in an interview today in the Malaysian capital. Alstom SA (ALO) isn't on the shortlist, he said. He declined to elaborate further on the bidders.
State-owned MRT intends to open the 51-kilometer (32-mile) line by July 2017, Azhar said, as the government tackles congestion and pollution from rising traffic. The full three- line network will carry 2 million passengers a day when complete and may cost 48 billion ringgit including rolling stock, according to a 2010 government estimate.
The first line will run from the southern suburbs of Kajang to the northern district of Sungai Buloh via the city center. MRT Corp. in January awarded the first major construction contracts, worth a total 1.74 billion ringgit, to IJM Corp. (IJM) and Ahmad Zaki Resources Bhd. (AZR)
The full 156-kilometer long network, which includes some underground sections, is due to be completed by 2020. A new cost estimate will be announced by year-end once key contracts have been awarded, Azhar said.
The government intends to raise as much as 30 billion ringgit through an Islamic bond program this year to help fund construction, Azhar said last month. The project is part of a $444 billion private sector-led investment program championed by Prime Minister Najib Razak to spur growth in the Southeast Asian nation.
To contact the reporter on this story: Chong Pooi Koon in Kuala Lumpur at firstname.lastname@example.com
To contact the editor responsible for this story: Neil Denslow at email@example.com.


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Jun 3, 2005, 05:03 PM | #1 |
How To Maintain My iBook
I am very happy with the switch to Mac, but I am wondering whether there is anything I need to do periodically such as "defragging" or cleaning up my hard drive? Any advice would certainly be appreciated! Thanks!
0 |
Jun 3, 2005, 05:09 PM | #2 |
defragging is not need on macs, just one more thing u can love about em
"We can't all be heroes because somebody has to sit on the curb and clap as they go by." Will Rogers |
0 |
Jun 3, 2005, 05:09 PM | #3 |
I've been wondering the same thing about the hard drive...
I also just purchased an iBook(and loving it!)...and have been doing lots of video. I used to defrag my drive back before OSX came out, but unsure whether it's still necessary in this day and age. I'm working on an iMovie/DVD project right now, and the project w/video is around 30gb, which I've been adding-to, copying, moving, deleting, etc. Was wondering how much that all effects the drive's long-term health. I got the 80gig, so I still have about 30virginGB that've never been touched.
But I've still got one of those Norton-Defrag-colored graphic visions in my head getting all chunked up as I move all these big files around. |
0 |
Jun 8, 2005, 12:43 PM | #4 |
yep, that's what my ibook is for too! mostly iMovie stuff, and eventually (i guess) Final Cut. i wonder the same thing- does having big big big a.v. files sitting there cause problems at all? if so i'll just load finished projects to an external drive (they're so cheap), but i'm only going to do that if/when i have to. for now i've just been saving iMovie files as highquality QuickTime files (once i've decided for sure that the editing is done). the Quicktime versions are far smaller (but of course can't be edited anymore). that way i can trash the actual iMovie files which frees up lots of room (but you have to REALLY know you're done editing!)
so there's no monthly sort of maintaince we have to do to keep the mac running smooooooth? it can't REALLY be no maintainance, can it? |
0 |
Jun 8, 2005, 12:53 PM | #5 |
This has been asked before, but that's not your fault.
MODS _ can we maybe have a sticky on this subject, as a lot of noobs want to know this information. On topic: Your Mac should not need defragging, files over a certain size automatically get defragged. One thing you will want to do is to repair the drive permissions from time to time. Applications>Utilities>Disk Utility Click on your drive and then click "Repair Disk Permissions". Do this especially after installs/updates. Also leave your Mac on overnight from time to time; the Mac OS X runs "janitor" programs during the middle of the night to keep things tip-top automatically. Hope this helps. Try a search of these forums (and of course Google) to find out more! "Mac Maintenance" would be good keywords. |
0 |
Jun 8, 2005, 01:34 PM | #6 |
Also leave your Mac on overnight from time to time; the Mac OS X runs "janitor" programs during the middle of the night to keep things tip-top automatically.
Leave it awake overnight? Or sleeping? And if sleeping, isn't it good to let it sleep more often than shutting it down anyway? |
0 |
Jun 8, 2005, 02:15 PM | #7 |
What's a day on MR without recommending AppleJack? (Looks like I'm not going to find out! )
Install it, run it about once a month (from single user mode), and you'll be a happy kamper.
*The season starts too early and finishes too late and there are too many games in between. Bill Veeck
0 |
Jun 8, 2005, 02:18 PM | #8 | |
0 |
Jun 8, 2005, 02:18 PM | #9 | |
0 |
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Sleepy Hollow: TV Review
The Bottom Line
Ichabod Crane arrives in the modern day Sleepy Hollow. He's followed quickly by the Headless Horseman. There are scores to settle from the past and tons of secrets in the present. A lot of unexplained phenomena here, but also a lot of fun if the emphasis stays more on the ridiculous and less on the mythological.
Airs tonight on Fox at 9
Created by
Alex Kurtzman and Roberto Orci
Tom Mison, Nicole Beharie, Orlando Jones
Fox's new drama gets better the more silly and fun it becomes. Awesome Ichabod Crane? Crazy Headless Horseman? Popping up in the modern day? Opt in on that and get yourself entertained.
Every series that's trying to be complex or challenging is in some ways asking the audience to go along for the ride. Such as, we have a really intentse long-term story here and we'd appreciate it of you'll come along for the ride every week for the next, you know, two or three months. Or, more likely, there's an element the audience just has to accept or there's no entry.
PHOTOS: Fox's 2013-14 Season: 'Rake,' 'Sleepy Hollow,' 'Almost Human' and 'Brooklyn Nine-Nine'
Like when Lost introduced the polar bear on a tropical island, etc. Those are your opt-in or opt-out moments (and for me, the polar bear was unabashedly an opt-in moment). In Fox's new Sleepy Hollow, not only does Ichabod Crane (Tom Mison) pop up in the modern day town of Sleepy Hollow, but hot on his tail is the Headless Horseman. At the very least, that's a time-travel issue, yes? And thus it become a fish out of water story when Crane (already reimagined as less the cowering thing of the past and now a buff, handsome Revolutionary War fighter) arrives in present times, startled by an overabundance of Starbucks outlets.
But that, people, is what makes Sleepy Hollow worth watching. It's fun, it's entertaining, it's got some scares and some action and plenty of secrets to unveil. Now, the caveat here is that who the hell knows how the show will evolve going forward. But the less dense mythology aspects giving way to more ridiculous "just go with it" moments would do wonders for the series.
Sleepy Hollow was created by Fringe and Star Trek's Alex Kurtzman and Roberto Orci, so you absolutely know that some kind of paranormal backstory is in place. And that's fine, too. But what makes Sleepy Hollow immediately likable is Mison's Ichabod Crane, who is confused about the modern world moments, and the relationship he shares with Sleepy Hollow police officer Abbie (Nicole Beharie) who at least believes enough of the existing evidence suggesting the craziness Crane's spewing might be true. (Part of that willingness stems from her own secrets and past.) Her superior (played by Orlando Jones) is right to think that Crane is really just a nutcase and things will settle down soon enough.
STORY: Fox's 'Sleepy Hollow' Will Have a 'Darker Look' But 'Fun Tone,' Says Co-Creator
They don't.
That Headless Horseman is coming back for something important (think about it). And he's extremely dangerous. This is where Kurtzman and Orci put in more complex mythology and, once you've come up with this kind of premise, there has to be more to it, so no fault there. It's just that all the chills and gore are, at this point, less appealing than the fish out of water story and the human relationship between Crane and Abbie. There so much to mine about waking up and asking a detective if he knows George Washington.
Oh, and about that. Sleepy Hollow's biggest reach is that not enough characters in it are properly freaked out about their current situations. You'd think that more time would be spent on the "how the hell did I get here" stuff and the "what is this car thing we're in" moments. Everybody buys in a little too quickly on that.
But again, somewhere about the middle point of tonight's premiere, when things get ever-more outrageous, they also get ever-more fun. So your opt in moment just may be that you need to stop thinking and go with it. You need to allow yourself to have more fun. There's a place for Breaking Bad in the TV world and there's a place for made-up and mashed-up stories that you just need to succumb to and be entertained by.
STORY: Fox Drama Series Orders: 'Sleepy Hollow,' 'Rake,' 'Gang Related,' 'Almost Human'
Am I worried about future episodes – sure. That's true about pretty much all of the new fall shows that seem to show promise. But I liked enough of the crazy-ass elements of Sleepy Hollow to give it a relatively long leash.
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Section Patrol Craft Photo Archive
USS Lenape (ID 2700)
ex-USAT Lenape
Civilian call sign (1919):
Love - Cast - Rush - Boy
served both the U. S. Army and Navy.
Built in 1912 by Newport News Shipbuilding Co., Newport News, VA
Launched in 1912
Delivered 18 January 1913
Acquired by the Army 1 June 1917 and named
USAT Lenape
Acquired by the Navy 10 April 1918
USS Lenape (ID 2700)
, 24 April 1918
Decommissioned 28 October 1918 and returned to the U. S. Army for return to her owners, the Clyde Steamship Co.
Burned 18 November 1925 and scrapped.
Displacement 3,389 t.
Length 398'
Beam 50'
Draft 18' 6"
Speed 15 kts.
Complement 226
Armament: One 5" and one 3" mount
Propulsion: Two 1,750ihp steam engines, two shafts.
Click on thumbnail
for full size image
Image Description
SS Lenape
Tommy Trampp
Undated post card
Original photo:
Courtesy of Boatswain's Mate First Class Robert G. Tippins, USN (Retired), 2005
Naval Historical Center photo NH 102877
Replacement photo: Post card dated 6 April 1913
Original photo: Robert Hurst
Replacement photo: Tommy Trampp
Underway off Jacksonville, Florida, circa the mid-1910s
Color tinted post card published by E.C. Kropp Co., Milwaukee, Wisconsin
Donation of Charles R. Haberlein Jr., 2008
Naval History and Heritage Command photo NH 105832-KN
Robert Hurst
Underway prior to 1917
Donation of Charles R. Haberlein Jr., 2008
Naval History and Heritage Command photo NH 105904
USAT Lenape
In French waters serving as a transport, circa 1917
Naval Historical Center photo NH 104492
Robert Hurst
In port, possibly when she was inspected by the Third Naval District on 9 April 1918, the day before she was taken over by the Navy
Naval History and Heritage Command photo NH 99542
USS Lenape (ID 2700)
At the New York Navy Yard, 20 August 1918.
U.S. Navy photos NH 51273 and NH 51274
Naval Historical Center
Dictionary of American Naval Fighting Ships:
, a troop transport, was launched by Newport News Shipbuilding Co., Newport News, Va., in 1912. Operated as an Army transport during the first part of World War I, acquired by the Navy 10 April 1918; and commissioned 24 April 1918, Comdr. Robert Morris in command.
sailed early in May 1918 with troops and equipment for European duty, arriving Brest, France, on the 23d. After returning to Newport News 6 June, the transport made two additional voyages to France, debarking troops at French ports for the vital campaigns of World War I. Returning from her third cruise in late summer,
was returned to the Army 28 October 1918.
Back To The Main Photo Index
Back to the Identification Numbered Vessel (ID) Photo Index
Comments, Suggestions, E-mail
This page created and maintained by
Joseph M. Radigan


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Crews Inspect Turnpike Bridge Damage In Southeast Wichita
Reporter: KAKE News
Thursday, May 24, 2012
Officials have closed one lane of traffic in each direction on Harry as crews inspect damage to the turnpike bridge.
Traffic was reduced to one lane around 12:30 p.m. Thursday.
KAKE"s Lily Wu reports concrete from the bridge started falling onto Harry. There are no reports of damage to vehicles.
It is unknown what caused the concrete to fall.
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Actually - a great ride is to start at the bottom of onides and climb for up to two hours, then rip the down hill. Epic. Also give north star a try.
- Trailspotting Lake Tahoe - Best Hikes
- The Dolder Nature Trail
- Blackwood Canyon, Ellis Peak 4x4 Road, California


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Hi Bryan, On 01/03/2010 12:27, SULLIVAN, BRYAN L (ATTCINW) wrote: > But if the same information can be derived from MCC and MNC (which > presumably it can), then I agree a Boolean will suffice for roaming. > But we need to be sure that the MCC/MNC (home and visiting) are > things that the application can determine through the SysInfo API. Is it safe to assume that both MCC and MNC are unsigned shorts? MaxReceived on Monday, 1 March 2010 14:45:16 GMT
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We are so excited to announce our first virtual book club, hosted […]
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You may not have noticed, but an unprecedented theatrical experiment was launched nationwide last week. Its San Francisco segment unfolded the night of Nov. 23 before an audience of 80 to 100 people in a modest wood-shingled community center atop Potrero Hill, with the playwright who started it all in attendance.
Suzan-Lori Parks's 365 Days/365 Plays project — a national yearlong grassroots theatrical festival premiering a unique and audacious play-a-day cycle by one of the country's foremost dramatic voices — took off at a benefit performance put on by the Z Space Studio as a group of 11 performers, directed by Lisa Steindler and director-actor Marc Bamuthi Joseph, unveiled the first seven playlets in the cycle.
The pieces (each no longer than 10 minutes) percolate with a mixture of mischievous invention, absurdist humor, pointed irony, and somber reflection on a variety of themes. In the first, for example, the aptly titled Start Here, an African American man gets vague encouragement and direction as he prepares, with some trepidation and confusion, to head out on a path as obscure, ambiguous, and mysterious as the history behind him. (The names of the characters, Arjuna and Krishna, invoke the tale of the Bhagavad Gita and overlay it on this seemingly American allegory.) In another piece, a young woman from a long line of "good-for-nothings" fails miserably to make nothing of herself — rejected by a crowd as inadequately worthless, she is forced to reinvent herself as something instead.
In Veuve Clicquot, which deftly reframes a comic situation into one of pathos and acute ambivalence, a seeming gourmand is in the process of ordering a sumptuous meal until his waiter balks at his pretension, and a chorus of women haunts him with the ethereal voice of his departed victim — whose own last meal, as it turned out, was nothing all that special.
Well acted and smartly blocked on and around a nearly bare stage (with some choice choreography added by six female dancers), the evening's performances coincided with similar premieres around the country involving a wide range of local theater companies (more than 800 and counting) that have each signed on to produce a week's worth of Parks's yearlong cycle (which she composed daily for one full year, beginning in November 2002). Locally, the project is spearheaded by the Z Space Studio, Playwrights Foundation, and Cutting Ball Theater (the last of which recently staged a very fine production of Parks's The Death of the Last Black Man in the Whole Entire World). The Bay Area manifestation of the 365 Days/365 Plays festival (which runs daily to Nov. 12, 2007) will ultimately involve more than 40 companies and 300 theater artists. This week's shows are by the all-female Shakespeare company Women's Will.
Parks — the Pulitzer Prize–winning creator of Topdog/Underdog, In the Blood, and The America Play, among other works (including screenplays and a novel) — was in a jocular and expansive mood during the Q&A. She explained her commitment to the idea of writing a play a day for one year as the product of an inclination to entertain any idea that comes into her head — "through the window of opportunity," she laughed, nodding to the suspended prop window stage left that had featured as the thematic and titular center of one of that evening's seven playlets.
Plays in the cycle beyond these first seven run a varied and quirky gamut of inspirational matter, with themes of war, family, and spiritual life among the leitmotifs. There are pieces that revisit some of the playwright's favorite themes (Abe Lincoln comes around again), some that pay homage to people who happened to have passed on during the course of the year (Johnny Cash, for instance), others that take off from real-life encounters (one piece incorporates Parks's meeting with Brad Pitt, for whom she was developing a screenplay).
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Archiving, Backup, Backup & recovery, Backup and Recovery, Backup and recovery software, Backup and restore, Backup Exec, BRMS Backup, Brocade, Business Continuity, Computer Associates, Data archiving, Data backup, Data protection, Data Recovery, Data storage, Defragmentation, Disaster Recovery, Disk drives, EMC, Exchange Backup, Fibre channel, HARD drive, Hard drives, HDD, iSCSI, NAS, NetApp, NFS, NTBackup, NTFS, RAID, RAID 1, RAID 5, RAID configuration, Replication, SAN, SAN management, SATA, SCSI, SSD, Storage Area Network, Storage arrays, Storage in 2010, Storage management, Storage products and equipment, Storage virtualization, Tape Backups, Tiered storage, VTL VIEW ALL TAGS
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While born in St. Louis, Missouri she was raised in Hollywood by her father silent movie actor Wilbur Higby and her mother who was in real estate. She worked on most of the network radio shows in Hollywood through the 1930s. Miss Higby then moved to New York where she appeared on nearly 50 (radio) soap operas and starred on 'When a Girl Marries' ...
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In today's episode of Political Empire we talk about the latest goings-on with financially strapped San Bernardino and what's next for longtime Republican Congressman Jerry Lewis now that he's retiring.
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Grammar Tips: Bad vs. Badly
"I felt badly" or "I felt bad"? The quick answer is that you should not say "I felt badly" unless you are describing a problem with your fingers or your sense of touch–the way in which you perform the physical act of feeling. Here's why:
Badly is an adverb, meaning it modifies a verb, adjective, or another adverb. In our example sentence, "I felt badly," the verb is "felt," meaning that badly modifies the way you feel–not your emotional state, but the literal action of moving your fingers. Bad, on the other hand, is an adjective, meaning it modifies a noun. In our example sentence, the noun is "I," meaning that bad modifies something about me–in this case, my emotional state. That's why it's correct to say "I felt sad" and not "I felt sadly."
At the same time, there are occasions when you should use the word "badly," namely when the verb you employ suggests action rather than a state of being. "The actor performed badly" or "the discussion went badly," for instance, are correct because performed and went are both action verbs, requiring an adverb to modify them.
It might surprise some of our readers to learn that this is a matter of great debate, dating back to at least this New York Times article from 1879. Check it out for a far more elaborate, tongue-in-cheek explanation of the grammatical rules informing these phrases.


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This is a fine time to be Arkansas coach Nolan Richardson. The NCAA investigation that haunted his program for 16 months has been completed, resulting in a mere slap on the wrist. His beloved 40 Minutes of Hell defense, missing in action for the last couple of seasons, is back in full infernal force. And just one year after missing the NCAA tournament for the first time in 10 seasons, his Razorbacks were 20-3 through Sunday and sitting atop the SEC Western Division with a 9-1 league record, their best start ever in the conference. The Arkansas team that beat Ole Miss and Vanderbilt in Fayetteville last week to improve its national ranking to 12 is basically the same club of average shooters that went 18-14 last season. But unlike the 1996-97 Razorbacks, these Hogs are winning close games, winning on the road and winning with a zeal that tempts Richardson to call it the best defensive team he's ever coached. Certainly, he says, "it's one of the most unusual teams I've coached." Personifying Arkansas's unconventionality is 6'9", 201-pound senior center Nick Davis, a born-again Christian with the rebounding instincts of Dennis Rodman and the ferocity of a school crossing guard. "Nicky is the nicest guy I've ever met who is a good rebounder," says Richardson. A junior college transfer who averaged only 3.6 points and 3.5 rebounds during his first two years in Fayetteville, Davis delivered his soul to God and his body to the weight room last summer. The resulting confidence and extra 16 pounds of muscle have helped him elevate his game: Through Sunday he was second in the nation in rebounding with an 11.9 average, and his 2.3 blocks a game placed him third in the conference. Though his jump shot is unsightly--it has been compared to someone loading and firing a musket--it serves him well. He has had 12 double doubles this season (he had one in his first two years), and his 12.4 points a game was second among the Hogs. "Nicky still looks like a rag doll out there," says Richardson, "but he has made our team much better." So has junior guard Pat Bradley, a Bostonian who was most likely headed to St. Bonaventure or Boston University before Richardson spotted him at the national 17-and-under AAU tournament 3 1/2 years ago and fell in love with his feel for the game and his three-point shooting. Bradley, the Hogs' leading scorer (14.3 points) and thief (43 steals), has in turn fallen in love with Arkansas"even the constant smell of manure from the fahms," he says. Who knows how far the Razorbacks can go in the NCAA tournament, but anyone who saw them dismantle Mississippi 100-87 last week for their 12th win in 13 games couldn't help but think about the Arkansas national-title team of four seasons ago. Issue date: February 16, 1998 |
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On Sunday, November 25, 2012, Diversity Focus debuted the first episode of its new television series, "Journey."
"Journey" is a four-part, 30 minute TV series chronicling diversity in the Corridor through the true stories of Eastern Iowans. The subjects featured are an American-born Muslim, a married lesbian with a family, an immigrant from a war-torn African country and a trio of Millennials who make the Corridor their chosen home.
Episodes air at 11:30am on KCRG-TV9 on December 2nd, 9th and 23rd. PATV-18 in Iowa City is airing each episode every Monday at 7:30pm and Saturday at 12:00 noon through the end of the year.