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Sarel van der Merwe
Sarel Daniel van der Merwe (born 5 December 1946) is a South African former rally driver, who was a multiple South African Rally Drivers Champion. He is sometimes referred to as "Supervan".[1]
Van der Merwe won the South African Rally Drivers Championship a record eleven times in 1975, from 1977 to 1985 and in 1988. Van Der Merwe also drove one NASCAR Sprint Cup race at Watkins Glen for Hendrick Motorsports #17 Tide Chevrolet Lumina team in 1990 while the team's regular driver, Darrell Waltrip, was recuperating from a severe leg injury a month earlier,[2] where he finished 24th;[3] van der Merwe had attempted to qualify for the 1988 Daytona 500 in a Hendrick-owned car, but failed to make the race.[4] He also held the SA Saloon Car Championship (1994), SA Modified Saloon Car Championship (1994 & 2001), and won the 1996 Castrol International Rally ending in Swaziland. He received his Springbok Colours in 1976 and his South African National Colours in 1997. In 2002, van der Merwe was awarded the Motorsport South African (MSA) Lifetime Achievement award.[5]
Van der Merwe began his racing career in 1967 racing saloon cars. His international career took off in 1983 in the IMSA series in the USA, with his most notable win in the 1984 24 Hours of Daytona race driving for Kreepy Krauly Racing, an all-South African team in a March 83G-Porsche. He shared the win with Graham Duxbury and Tony Martin. Van der Merwe did exceptionally well in the 1984 24 Hours of Le Mans where he finished 3rd on debut. In the 1986 Le Mans race, Sarel pulled in a lap early and Jo Gartner took over. A lap later the suspension broke and the car veered off the Mulsanne Straight in the middle of the night and Gartner was killed.
His South African rallying days were extensive and colourfull, and he displayed spectacular driving skills even under severe weather conditions. He started off with a private D.K.W. around 1965, a motor car that had the reputation of being unbreakable, even so by Van. He then moved up the ranks to sport a works-Ford Escort Mk II BDA (Belt Driven Assembly), the state-of-the-art machine around 1975−1979. The yellow car was jointly sponsored by the Ford Motor Company and Southern Suns hotel group, and later in the blue colours of Kreepy Krauly (South Africa). After leaving Ford because of a disagreement, Supervan had a short stint in the Datsun 160Y and Datsun Stanza, teamed up with U.K. rally ace Tony Pond around 1980. But van der Merwe always complained that his lanky body did not fit into the smaller Japanese cars. His final rally successes were in a factory team Audi Sport Quattro (1981−1986) with his rally swan song in the Volkswagen Golf front wheel drive hatchback in 1988. His co-driver/navigator was the ever-faithful Franz Boshoff, also a crowned Springbok, through all the years rallying with Ford, Datsun, Audi and Volkswagen.
He retired from competitive motor racing on 23 November 2002 after Round 12 of the Vodacom Power Tour at Kyalami.[6]
- ^ McGeorge, Lee (30 July 2009). "Supervan and Wyndham on track at Killarney". Motoring.co.za. Motoring & Independent Online. Retrieved 1 September 2009.
- ^ Rhodes, Beth (August 2, 1990). "Waltrip's Sub: van der Merwe - Road-Racing Star to Debut in Budweiser At The Glen". Orlando Sentinel (Orlando, FL). p. C6. Retrieved 2013-03-27.
- ^ Sarel van der Merwe - NASCAR Sprint Cup Results. Racing-Reference. USA Today Sports Media Group. Accessed 2013-03-27
- ^ "Allison, Waltrip Easily Win 125-Mile Races at Daytona". The State (Columbia, SC). February 12, 1988. Retrieved 2013-03-27.
- ^ "MSA Handbook 2007". MOTORSPORT SOUTH AFRICA. Retrieved 2008-10-22.[dead link]
- ^ "Sarel van der Merwe". HISTORIC RACING. Retrieved 2008-10-22.
Sporting positions | ||
Preceded by Herman Fekken |
SA Rally Drivers Championship 1975 |
Succeeded by Jan Hettema |
Preceded by None |
SA Group 1 / Group A Championship 1977 |
Succeeded by Giovanni Piazzo-Musso |
Preceded by Jan Hettema |
SA Rally Drivers Championship 1977 to 1985 |
Succeeded by Hannes Grobler |
Preceded by Geoff Mortimer |
SA Rally Drivers Championship 1988 |
Succeeded by Serge Damseaux |
Preceded by Terry Moss |
SA Saloon Car Championship 1994 |
Succeeded by Michael Briggs |
Preceded by None |
SA Modified Saloon Car Championship 1994 |
Succeeded by Charl Wilken |
Preceded by R du Plessis |
SA Modified Saloon Car Championship 2001 |
Succeeded by Johan Fourie |


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Contact |
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If you can't make it for our first workshop, we're giving you one more shot. Why not bring summer indoors with you this fall, with your own fleet of glowing fireflies? In this workshop you'll learn how to make your own firefly that senses and responds to blinking lights, and is powered by a small computer. No previous programming is needed, and we'll provide all the parts for you to make a firefly of your own to take home. Ages 13+, 20 spots available.
Update as of 9/24: We're sorry but this workshop is at capacity. Thanks for your interest and we hope you'll sign up for future events.

subset: commoncrawl


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# SUNDAY MORNING COMING DOWN Well I woke up Sunday morning With no way to hold my head that didn't hurt And the beer I had for breakfast wasn't bad So I had one more for dessert Then I fumbled through my closet Through my clothes and found my cleanest dirty shirt And I washed my face and combed my hair and stumbled down the stairs to meet the day Well I smokes my mind the night before with cigarettes and songs that I'd been a'pickin' Then I lit my first and watched a small boy Cussin' at a can that he was kicking Then I crossed the empty street and caught the Sunday smell of someone frying chicken And it took me back to something that I lost somewhere somehow along the way Chorus On a Sunday morning sidewalk Wishing Lord that I was home Cause there's something in a Sunday Makes a body feel alone And there's nothing short of dying Half as lonesome as the sound Of a sleeping city sidewalk Sunday morning coming down In the park I see a daddy With a laughing little girl that he was a'swinging And I stopped beside a Sunday school And listened to the songs that they were singing Then I headed back for home And somewhere for away a lonely bell was ringing And it echoed through the canyon Like the disappearing dreams of yesterday Repeat chorus... Comments
Popular Misc Country tabs & chords Song lyrics. Misc Country lyrics
↑ Back to top | Tablatures and chords are parodies/interpretations of the original songs. You may use it for private study, scholarship, research or language learning purposes only |


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Copyright © 1988 All rights reserved.
Cell, Volume 54, Issue 7, 1073-1080, 23 September 1988
Add/View Comments (0)A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor
Didier Picard, Stephen J. Salser and Keith R. Yamamoto
- The glucocorticoid receptor is a signal transducer that interacts both with the signal and with the genes it regulates. We showed previously that nuclear localization of the receptor requires hormone binding. We have now constructed recombinant receptors that relieve hormonal control of nuclear localization, and we demonstrate that the DNA binding/transcriptional regulatory functions of the receptor are also regulated directly by hormone. Surprisingly, regulation by the steroid binding domain appears to be relatively independent of protein structure. For example, regulation is maintained when the steroid binding region is repositioned from the C-terminus to the N-terminus of the receptor. Furthermore, the activity of an unrelated protein, the adenovirus E1A gene product, becomes hormone regulated upon fusion to the steroid binding domain. We speculate that the inhibitory effect of the unliganded steroid binding domain may be mediated by heat shock protein hsp90, which binds selectively to the unliganded receptor.


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Items on this web page are general in nature. They cannot—and should not—replace consultation with a competent legal professional. Nothing on this web page should be considered rendering legal advice.
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On September 19, 2013, Dale Gipson lead a lunch-and-learn session for local business owners interested in government contracts and subcontracts. The presentation addressed teaming agreements, negotiating and managing subcontracts, joint ventures, and various small-business issues.
On September 12, 2013, Rich Marsden and Dale Gipson spoke at the 2013 Rocket City GovCon. Mr. Marsden spoke on managing government contracts and subcontracts and Mr. Gispon on the latest developments in bid protests.
On August 22, 2013, Dale Gipson lead a lunch-and-learn session for local business owners interested in the latest developments in bid protests in government contracting. The presentation identified the latest trends in bid protests, provided an overview of how the process works, and suggested ways to "win" protests.
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Obituaries OBIT: Enriqueta Garcia
for Employment Opportunities
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Rodriguez leads Hidalgo County District Attorney's raceWhen early voting results were released after polls closed at 7 p.m., Rodriguez had a lead in the race...04 March 2014Read More...
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Wed - Partly Cloudy/Wind. High: 68 Low: 46
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MISSION - Visitation for Enriqueta Garcia will be held 3 to 9 p.m. Thursday, April 21, 2011, with a 7 p.m. rosary at Ric Brown Family Funeral Home in Mission.
Funeral mass for Enriqueta Garcia will be at 10 a.m. at Ric Brown Family Funeral Home in Mission. Burial will be at San Jose Cemetery in Mission.
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::::: Web Series Today <== IMPORTANT read for WST "authors".
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Saturday, December 8, 2007
11 comments:
- AnonymousDecember 8, 2007 at 1:43 PM
i vote gemma, the taxis are driving on the other side of the road like in england..gemma is from england right?
ReplyDelete - NinjaPaperDecember 8, 2007 at 5:09 PM
Gemma? My second guess would have to be Peter from LJ15
ReplyDelete - AnonymousDecember 8, 2007 at 7:11 PM
I was actually hoping it would be Becki (Taylor)... Until she showed up on LG15 again.
Becki's so awesome. - robtomorrowDecember 8, 2007 at 8:29 PM
Soon is a relative term with Glenn we may not find out who Aly Zarin is until 2008.
But I am going for the long shot and vote for Jessica Rose herself.
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Verizon's Jetpack can connect up to 10 devices at once and critics liked the Jetpack's large screen and battery life. The Jetpack is an ideal companion for business travelers -- connect and then simply toss the device in your bag.
NEXT: Samsung Galaxy Camera, $499
The Mayans weren't the only ones who got it wrong this year. Here are a few of the worst predictions of 2012.


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Friday March 07, 2014
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The next step in ski education
December 19, 2012
By Hope Strong
Nordic element and new executive director on the horizon
One of the valley's oldest nonprofit organizations plans to merge with one of its newest in an effort to combine resources and reduce duplication while working with young athletes interested in taking their skiing and riding to a competitive level.
"We've got the best snow in the Rocky Mountains; there's no reason why we shouldn't have the best ski programs to take advantage of that," said Darcy Klausmann, interim president of the Teton Valley Ski Education Foundation, an organization that was formed in 1978 to promote ski racing.
Having evolved over the years to include snowboarding and freeriding components to complement its established Alpine skiing element, the Foundation board gave its nod of approval last week to a merger that would incorporate programs of the Teton Nordic Team, a more recently formed nonprofit that facilitates competitive cross-country skiing for all ages.
"My goal would be to create a ski culture," said TNT president Michael Bredal in favor of the merger with the Foundation. "Clubs like these have combined in Sun Valley, Bozeman and Jackson, enabling those groups to fully realize their potential. This is the beginning of something really good."
While residents of Teton Valley are always careful to maintain their identity when being compared to other mountain towns, those associations aren't so bad when you're talking about the strength of nonprofit organizations.
Founded in 1938, what is now called the Jackson Hole Ski & Snowboard Club began utilizing the Trail Creek Nordic Center around 1960, and Nordic skiing has been a part of the club ever since.
Sharing resources
With Jen Smith in place as its Executive Director just this year, Klausmann said the Foundation has never been in a better place to build administrative partnerships.
"With all the athletes, their coaches and training, travel to races, insurance and all the other details, the Ski Education Foundation is a pretty labor intensive nonprofit," Klausmann said. "Over the years, Jen has moved from the role of a volunteer to that of an administrator, providing valuable oversight and organization. Jen and her husband, Rick, were a turning point for the Ski Education Foundation, and now we are in a position to consider a merger with TNT that would broaden our volunteer base and take pressure off local businesses that support both organizations."
In order to focus on her own growing business, Smith will be phasing out of her role as executive director by the end of January, but she is excited for the hire of a new director that will manage all the Foundation's administrative details as this year's director of coaching, Al Clausen, orchestrates programming.
"The Ski Education Foundation was run completely by volunteers, but there is a point when you need to have someone in place to run the off-the-snow administration," Smith said. "This was my fourth season as a volunteer but my first as director, and I am really very proud how far we've come. When a new director transitions in, there will be a great opportunity to work to incorporate Nordic programming, as there are multiple athletes on both teams."
With roughly 12 coaches working with the Foundation, TNT has one in the competitive category, with two master coaches and one recreational coach. Different from the recreational ski school that operates at Grand Targhee Resort, the Ski Education Foundation focuses on all of its programming on competitive aspects of skiing and riding.
"Grand Targhee Resort has always provided a tremendous amount of support for the Ski Education Foundation," Klausmann said. "With the changes that are coming in the new year, we are hoping to grow and give back as much as we can."
Though a much larger organization with 40 more years under its belt, the Jackson Hole Ski & Snowboard Club boasts bringing in more than $1M to that community with races and events. By the way it's growing, the Teton Valley Ski Education Foundation has the potential to not only inspire athletes but also help support the local economy.
With the fiscal year of both the Ski Education Foundation and the Teton Nordic Team ending at the end of June, both boards agreed to shoot for a merger this summer.


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The Path to Best-in-Class Contract Management
The Future of Contracting Webinar Series - Part II
Weaknesses in contract management cost the average company 9.2 percent of annual revenue.* Staggering, right? Have you looked at how contract management is performing at your organization? Are you average?
Listen to this recorded webinar to learn what it takes to achieve high-performing contract management. Tim Cummins, CEO of IACCM, the world's leading contract management association, shares valuable insights and advice based on a survey of industry innovators. You won't want to miss the discussion of what tools and resources these experts use to reach best-in-class contract management.
One of the tools discussed in the webinar, a contracting maturity assessment, is available now. It only takes a few minutes, and it's free. We'll email you results that indicate how your organization compares to high performers, with some action items you can take to move forward.
Tim Cummins, CEO, IACCM
Dan Ashton; Senior Solutions Marketing Manager; Ariba, an SAP Company
*ROI of Contract Management, February 2012, IACCM


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State: Harris County has not done enough to cut jail population
Johnny Hanson, Staff
February 10, 2014 | Updated: February 11, 2014 12:39pm
State officials have rejected a request from Sheriff Adrian Garcia to increase the capacity of the Harris County Jail and said local leaders have not done enough in recent years to reduce the inmate population.To continue reading this story, you will need to be a digital subscriber to HoustonChronicle.com.
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"History does not long entrust the care of freedom to the weak or the timid" - Gen Eisenhower.
Sunday, August 21, 2011
Two Down, Three to Go
UPDATE: Based on current reports, the Ace of Hearts may only count as 1/2 gone . . . so far.
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Oxfam International (Oxford)
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January 06
South Sudan: Mediation Talks Critical to Ending Escalating Conflict in South Sudan [press release]
Oxfam deeply concerned about growing humanitarian crisis in the world's newest nation Read more »
January 02
South Sudan: Growing Humanitarian Impact of the Political Crisis in South Sudan - Oxfam Response [press release]
Responding to the growing humanitarian impact of the political crisis in South Sudan, Emma Drew, Oxfam's South Sudan Acting Country Director said from Juba: Read more »
December 27, 2013
South Sudan: South Sudan Government Agrees to Cease Hostilities - Oxfam's Reaction [press release]
Responding to the reported agreement by the Government of South Sudan to immediately cease hostilities, John Watt Oxfam's East and Central Africa Deputy Regional Director said from... Read more »
December 24, 2013
South Sudan: UN to Send More Troops to South Sudan - Oxfam's Reaction [press release]
Commenting on the decision for the UN to send more troops to South Sudan, John Watt, Oxfam's Deputy Regional Director for East Africa, currently in South Sudan said: "Protecting... Read more »
December 19, 2013
Niger: Areva in Niger - Who Is Benefiting From the Uranium? [press release]
Niger, one of the poorest countries in the world, and Areva, a world leader in nuclear energy spearheading France's economic diplomacy, have for the past several months been... Read more »
December 17, 2013
Sudan: Oxfam Strongly Condemns the Use of Violent Force Against Civilians, in Juba, South Sudan [press release]
Emma Jane Drew, Country Director (Acting) for Oxfam in South Sudan, said from Juba: Read more »
Africa: Oxfam Reaction to EU Court of Auditors Report On EU Climate Finance [press release]
Today the European Court of Auditors released its findings of an audit of European financial support to help developing countries cope with climate impacts. Read more »
Africa: U.S.$52 Billion for IDA, the World Bank's Fund for the Poorest [press release]
Donors have replenished the World Bank's fund for the world's poorest countries, the International Development Association, to the tune of $52 billion. Read more »
AllAfrica aggregates and indexes content from over 130 African news organizations, plus more than 200 other sources, who are responsible for their own reporting and views. Articles and commentaries that identify allAfrica.com as the publisher are produced or commissioned by AllAfrica.


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Simon Schaffer
Simon Schaffer | |
Simon Schaffer at a summer school in St. Petersburg, Russia (2001)
Born | citation needed] Southampton[citation needed] |
1 January 1955 [
Institutions | University of Cambridge Darwin College, Cambridge Imperial College, London UCLA |
Alma mater | Trinity College, Cambridge |
Thesis | Newtonian cosmology and the steady state (1980) |
Notable awards | Erasmus Prize (2005); Sarton Medal (2013) |
Website | |
www.hps.cam.ac.uk/people/schaffer |
Simon J. Schaffer (born 1 January 1955 in Southampton) is a professor of the history and philosophy of science at the Department of History and Philosophy of Science at University of Cambridge and was until recently editor of The British Journal for the History of Science.[1]
Schaffer was born in Southampton and educated at Varndean Grammar School for Boys in Brighton. He studied at Trinity College, Cambridge, where he captained the winning college team in the 1974 University Challenge; he went on to gain his PhD in 1980 with the thesis Newtonian cosmology and the steady state.[2]
After completing his BA, Schaffer went to Harvard University as a Kennedy Scholar, and had taught at Imperial College London and the University of California, Los Angeles. Schaffer has been a Fellow of Darwin College, Cambridge since 1985.
Schaffer has authored or co-authored numerous books, including Leviathan and the Air-Pump: Hobbes, Boyle, and the Experimental Life with Steven Shapin.[3] In addition to his work at Cambridge, he has been a presenter on the BBC,[4] in particular the series Light Fantastic broadcast on BBC Four in 2004.[5][6][7]
Awards and honours[edit]
In 2005 he shared the prestigious Erasmus Prize with Steven Shapin for Leviathan and the Air-Pump. This Dutch prize was handed over by the Dutch crown prince Willem-Alexander and can be regarded as a token of appreciation for the intrinsic value of his work for the history of science in general. In 2013 he received the Sarton Medal, the most prestigious honor awarded by the History of Science Society, in recognition of his "lifetime of scholarly achievement".
- ^ http://journals.cambridge.org/action/displayJournal?jid=BJH
- ^ Schaffer, Simon (1980). Newtonian cosmology and the steady state (PhD thesis). University of Cambridge.
- ^ Schaffer, Simon; Shapin, Steven (2011). Leviathan and the Air-Pump: Hobbes, Boyle, and the Experimental Life (New in Paper). Princeton, N.J: Princeton University Press. ISBN 0-691-15020-6.
- ^ "BBC Four - Mechanical Marvels: Clockwork Dreams".
- ^ "BBC - Press Office - Light Fantastic Simon Schaffer interview". Archived from the original on 2013-06-03.
- ^ Light Fantastic at the Internet Movie Database
- ^ Simon Schaffer at the Internet Movie Database
External links[edit]
- CBC interview—Ideas: How to Think about Science, podcast available
- Leviathan and the Air-Pump
- Simon Schaffer interviewed by Alan Macfarlane 27th June, continued 1st and 2nd July 2008 (film)
- Simon Schaffer's 2010 Tarner Lectures "When the stars threw down their spears": Histories of Astronomy and Empire
- Simon Schaffer's Videos at Imperial College


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Dynamics of arbuscular mycorrhizal symbiosis in heavy metal phytoremediation: Meta-analytical and conceptual perspectives
Titre: | Dynamics of arbuscular mycorrhizal symbiosis in heavy metal phytoremediation: Meta-analytical and conceptual perspectives |
Auteur: | Audet, Patrick; Charest, Christiane |
Résumé: | To estimate dynamics of arbuscular mycorrhizal (AM) symbiosis in heavy metal (HM) phytoremediation, we conducted a literature survey and correlated HM uptake and relative plant growth parameters from published data. After estimating AM feedback responses for these parameters at low and high soil-HM concentration intervals, we determined that the roles of AM symbiosis are characterized by (1) an increased HM phytoextraction via mycorrhizospheric 'Enhanced Uptake' at low soil-HM concentrations, and (2) a reduced HM bioavailability via AM fungal 'Metal-Binding' processes at high soil-HM levels, hence resulting in increased plant biomass and enhanced plant tolerance through HM stress-avoidance. We present two conceptual models which illustrate the important compromise between plant growth, plant HM uptake and HM tolerance, and further emphasize the importance of AM symbiosis in buffering the soil environment for plants under such stress conditions. This meta-analysis has revealed a transition role of the AM symbiosis in phytoremediation shifting from 'Enhanced Uptake' to 'Metal-Binding' beyond critical soil-HM levels. |
Date: | 2007 |
URI: | http://hdl.handle.net/10393/12931 |
Fichier(s) constituant ce document :
Fichier(s) | Taille | Format | |
Audet_Patrick_2 ... _mycorrhizal_symbiosis.pdf | 617.9Kb | application/pdf |
Voir/ |


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Contact:Nicholas Mirra, Communications Coordinator
(p) 215-242-9253, x311
JANUARY 31, 2012. PHILADELPHIA, PA. The Bicycle Coalition of Greater Philadelphia and the Community Design Collaborative (CDC) will unveil plans for a redesigned South Philly streetscape at a February 1st public meeting. The designs will suggest infrastructure changes to make South Philly streets safer and more appealing to pedestrians, bicyclists, and public transit users, while preserving vehicular traffic flow.
The design work is part of the Bicycle Coalition's new "Safe Streets For Healthy Neighborhoods" initiative. The advocacy group is examining how Philadelphia can apply innovative transportation infrastructure to improve its neighborhoods. The goal is to improve Philadelphia's quality of life by making its streets friendlier to bicyclists and pedestrians.
"We picked South Philly as our first focus because of its existing high rates of bicycling, and because there isn't much bicycling infrastructure," said Sarah Clark Stuart, Campaign Director for the Bicycle Coalition. "The City's bike plan calls for north-south corridors through South Philly, but they aren't in place yet, so this project can provide some of that initial legwork."
The Bicycle Coalition and the CDC design team held a first meeting last November near 12th & Passyunk, where they solicited the input of South Philly residents, commuters, and business owners. The design team will present initial designs at Wednesday's meeting, and offer another chance for public community feedback. The final conceptual designs will be presented in April.
"The Community Design Collaborative awarded the Bicycle Coalition a grant for this design work," said Susan Dannenberg, Research Fellow with the Bicycle Coalition. "This initiative is a terrific example of how Philadelphia's residents, politicians, advocates and designers can work together to make our streets more enjoyable and safer places to walk, shop, and commute."
While the initiative is not an official project commissioned by the City of Philadelphia, City departments are paying close attention. Dannenberg expects representatives from the City's Planning, Streets, Water, and Transportation and Utilities departments to be in attendance.
Date, time, and location of the meeting are below:
Wednesday, February 1, 2012
Guerin Recreation Center
1600 Jackson Street, Phila PA 19145
About the Community Design Collaborative
The Community Design Collaborative is a community design center that provides pro bono predevelopment design services to nonprofit organizations, offers unique volunteer opportunities for design professionals, and raises awareness about the importance of design in community revitalization.


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I'm Dan.
I'm known as a musician, actor & student.
Attending Hofstra University.
Music Merchandising major, Film/TV minor.
Aspiring Music Supervisor for Film & Television.
Catching Elephant is a theme by Andy Taylor
(Source: imgoingtodrinkmymugoftea)
There's a storm coming, Mr. Wayne. You and your friends better batten down the hatches, because when it hits, you're all gonna wonder how you ever thought you could live so large and leave so little for the rest of us.
(Source: mjolnr)
(Source: suzybishop)
(Source: minus-human)
Some more pictures form The Dark Knight Rises world premiere!!
Standard 35mm film compared to IMAX 70mm (full-scale sizes pictured)
(Source: all-batman)
New The Dark Knight Rises stills released today


text:
The Hottest Summer Romances of 2008 by POPSUGAR Celebrity 8/29/08 24 Reactions 1 Shares Print 0 1 0 0 0 As we get ready to bid farewell to another Summer, we thought it would be fun to look back at all the couples that took advantage of those steamy nights. There were old favorites, hot hookups that quickly fizzled, and one very exciting reunion — so take a look through our photos of the hottest Summer romances of 2008. Blake Lively and Penn Badgley What's Your Reaction? 0 0 0 0 0 0 Life really imitated art for Blake Lively and Penn Badgley, who couldn't keep their hands off each other during breaks from filming Gossip Girl — even though their on-screen counterparts called it quits at the end of last season. Source: Pacific Coast News Online 1 / 21 Lance Armstrong and Kate Hudson What's Your Reaction? 0 0 0 0 0 0 Kate Hudson and Lance Armstrong hooked up and wasted no time spending all of their time together with their families. They couldn't get enough of PDAs and playing sports together, but it turned out to be just a fling that burned out in late July. Source: Splash News Online 2 / 21 Rachel McAdams and Ryan Gosling What's Your Reaction? 0 0 0 0 0 0 We tried not to get our hopes up too high when Ryan Gosling and Rachel McAdams were spotted leaving a club together, but almost declared a national holiday when they showed that they were officially back together, kissing and snuggling over brunch. Source: INFphoto.com 3 / 21 Jake Gyllenhaal and Reese Witherspoon What's Your Reaction? 0 0 0 0 0 0 Jake Gyllenhaal spent most of his Summer shooting Prince of Persia overseas, but the newly beefed up actor got plenty of visiting time from Reese and her adorable kids. Source: Splash News Online 4 / 21 Jim Carrey and Jenny McCarthy What's Your Reaction? 0 0 0 0 0 0 One of our favorite funny couples, Jenny McCarthy and Jim Carrey, kept bringing the laughs this summer when he rocked her revealing black swimsuit on the beach over the Fourth of July. Source: Splash News Online 6 / 21 Ryan Reynolds and Scarlett Johansson What's Your Reaction? 0 0 0 0 0 0 Ryan Reynolds and Scarlett Johansson kept a low profile, but were still caught in some pretty adorable moments as they started to make plans for their upcoming wedding. 6 / 21 Ellen DeGeneres and Portia de Rossi What's Your Reaction? 0 0 0 0 0 0 Ellen DeGeneres and Portia de Rossi looked beautiful as they took vows and declared their love to each other at their gorgeous wedding in mid-August. Source: Getty 7 / 21 Cameron Diaz and Paul Sculfor What's Your Reaction? 0 0 0 0 0 0 Cameron Diaz found a new man in Paul Sculfor, and the happy couple are still kissing and strolling their way into the Fall. Limelight Source: Pacific Coast News Online 8 / 21 Vanessa Hudgens and Zac Efron What's Your Reaction? 0 0 0 0 0 0 Vanessa Hudgens and Zac Efron took some time away from shooting High School Musical 3 to get loved up in their swimsuits on the shores of Turks and Caicos in July. Source: NPG 9 / 21 Jennifer Aniston and John Mayer What's Your Reaction? 0 0 0 0 0 0 Jennifer Aniston and John Mayer kicked off the Summer with lots of time spent kissing and cuddling poolside. Even though she followed him on tour and introduced him to her BFFs, the hot new couple called it quits in early August. 11 / 21 Eva Longoria and Tony Parker What's Your Reaction? 0 0 0 0 0 0 Eva headed back to work on Desperate Housewives, but not before a few romantic vacations with Tony to Europe and New York. 11 / 21 Heidi Klum and Seal What's Your Reaction? 0 0 0 0 0 0 Heidi and Seal snuck in some alone time during a family vacation with the kids, getting romantic and taking photos together in Paris. Source: Splash News Online 12 / 21 Rihanna and Chris Brown What's Your Reaction? 0 0 0 0 0 0 Rihanna and Chris still won't talk about their relationship, but their Summer was packed with plenty of romantic getaways and activities like jet-skiing in Maryland. Source: Splash News Online 13 / 21 Orlando Bloom and Miranda Kerr What's Your Reaction? 0 0 0 0 0 0 Beautiful couple Orlando Bloom and Miranda Kerr took their love on vacation all over the world and around NYC on his motorcycle. Source: Bauer-Griffin Online 14 / 21 Mary-Kate Olsen and Nate Lowman What's Your Reaction? 0 0 0 0 0 0 Mary-Kate Olsen found Summer love, getting cute and cuddly over brunch with her new man Nate Lowman. Source: Splash News Online 15 / 21 Jessica Biel and Justin Timberlake What's Your Reaction? 0 0 0 0 0 0 The ever-busy Jessica Biel and Justin Timberlake found plenty of time for each other this Summer, cuddling up for low-key shopping trips and date nights. 16 / 21 Lindsay Lohan and Samantha Ronson What's Your Reaction? 0 0 0 0 0 0 Constant companions Lindsay Lohan and Samantha Ronson did almost everything together, from vacations to birthdays to parties galore. LL finally seems grounded thanks to her new gal pal, and both ladies continue to gush about their happiness. 17 / 21 Mischa Barton and Taylor Locke What's Your Reaction? 0 0 0 0 0 0 Mischa Barton took her love to the beach more than once, showing off her bikini body as she puckered up to her man Taylor Locke in the sand. Source: Pacific Coast News Online 18 / 21 Jessica Simpson and Tony Romo What's Your Reaction? 0 0 0 0 0 0 Jessica Simpson and Tony Romo enjoyed his Summer off as she started her country career and professed her love for her cowboy to People. 19 / 21 Balthazar Getty and Sienna Miller What's Your Reaction? 0 0 0 0 0 0 Sienna Miller caused a major controversy when she was spotted making out with married man Balthazar Getty all over Europe. Their topless PDA sessions created a scandal that the new couple is still trying to hide from. Source: INFphoto.com 20 / 21 Natalie Portman and Devendra Banhart What's Your Reaction? 0 0 0 0 0 0 Natalie Portman's boy of Summer was Devendra Banhart, and the quirky couple beat the heat together in NYC and all over the world. Source: INFphoto.com 21 / 21 0 1 0 0 0 Read More PopSugar SlideshowSummer 2008Paul SculforRyan ReynoldsRyan GoslingRachel McAdamsCameron DiazScarlett Johansson Get a Personalized Celebrity & Entertainment Newsletter! Help us customize your newsletter by selecting your interests (optional): Scarlett Johansson Cameron Diaz Young Hollywood A Listers Nataliee2007 5 years Rachel & ryan Obvv :) there just too cutee <3 Nataliee2007 5 years Rachel & ryan Obvv :)there just too cutee <3 Penny4545 5 years ryan and rachel!! they couldn't stay apart for very long =) must be meant to be. angelbaby2 5 years ryan and rachel angelbaby2 5 years ryan and rachel ghostwriterchic 5 years Ryan and Rachel!! 4EVA! ghostwriterchic 5 years Ryan and Rachel!! 4EVA! michelleexxxx 5 years RYAN AND RACHEL! SOOO HAPPY! hope they stay together this time! Mesayme 5 years Rachel and Ryan of course...anytime you can be apart and come together is a great sign of stability for a future. I hope they couldn't bear to be apart...then staying together is smooth sailing. robinesque 5 years I like ZANESSA!! White boy likes it a little caliente!! spicyaroma 5 years Ryan & Rachel forever! spicyaroma 5 years Ryan & Rachel forever! Link Love Kate Hudson may not lose her guy after all — Us Weekly Why is Gloria Steinem praising Jennifer Aniston? — People Johnny Depp goes digital in his latest movie poster — ET Terry Richardson responds to recent sexual assault allegations — HuffPost Celebrity Did Lea Michele's new album end the Glee curse? — Hollywood Reporter It's officially Rihanna and Drake dating news week — Lainey Gossip Ariana Grande gets a neck tattoo — Gossip Girl The most important moments from Jennifer Lopez's new music video — BuzzFeed What's with all the Drake-themed apps? — Vulture Rachel Bilson and Hayden Christensen have an adorable date night — JustJared
When 'Die Hard' Is Cast With Pugs And Teddy Bears, It Becomes The Cutest Action Flick Ever Huff Post Celeb 1.1K Shares
Amanda Seyfried Unknowingly Carries Knife On Plane, Alerts TSA Via Twitter Huff Post Celeb 139 Shares
Things Got Really Awkward Between Piers Morgan and Chelsea Handler Last Night 42 Reactions 2.7K Shares
Celebrity Apprentice Season 14: Brandi Glanville, Kate Gosselin, Ludacris, and More Join Us Weekly 2.8K Shares


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Receivers & Amplifiers
Parasound - Classic 2100 Stereo Pre-Amp
Parasound's NewClassic Model 2100 is a versatile two-channel preamplifier that's equally expert with venerable and modern technology, from vinyl to MP3. A low-noise phono input provides the correct gain and load for both MM and MC cartridges. The Model 2100 also enables you to upgrade your present surround sound system for serious two-channel, audiophile-quality listening. Left,...
Parasound - 2125 125-Watt THX Ultra2 Two-Channel Amplifier
Power, Features, Build, and Affordability Parasound's New Classic Model 2125 is destined to be the company's most popular two-channel power amplifier. Its winning combination of power, features, build quality, and affordability make it a must-have for all but the most demanding systems. And the THX Ultra2 certification means that it meets the highest performance standards for...
Sangean DT-110 Digital Pocket AM/FM Stereo Receiver
PLL synthesized digital tuning with up to 24 presetsStereo headphone jackDigital LCD display90-minute automatic shut-offFeatures deep bass boostRotary volume controlRequires 2 AAA batteries (not included)
Sangean SR-3 AM/FM Pocket Size Receiver
AM/FM stereo radio and stereo/mono switchBuilt-in speaker with deep bass boostDimensions: 2" W x 3 5/16" H x 11/16" DUses 1 AA battery (not included)Includes earbuds trailing antenna and neck strap


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Business Development jobs
Found 233 Marketing, Media & Advertising jobs
Order by: Newest first Salary
Partnerships Account Director - eCommerce Business
- London
- to £45,000 + bonus + stock + benefits
Partnerships Account Director required for one of the UK's leading eCommerce businesses.
Digital Senior Sales Manager - Leading Ad Tech Business
- London
- £40000 - £50000 per annum + 100% COMMISSION
Digital Sales Manger Location: London Salary: £40,000-50,000 per annum + excellent benefits Incredible opportunity top join a small but growing team an...
Brand Partnerships Sales Manager
- London
- £30000 - £35000 per annum + excellent commission & benefits
Video Brand Partnerships Manager £30-35k & excellent commission London Unique opprtunity for a talented and creative agency sales person to join a smal...
Agency Sales Manager - SPORT
- London
- £30000 - £35000 per annum + competitive commission
Agency Sales Manager £35-40k & Competitive commission London Seeking a tenacious digital sales person with strong agency contacts to join an ambitious age...
Business Development Manager - Cloud Services
- London
- £50000 - £60000 per annum + commission, package
Amazing new mobile first digital agency start-up seeks BDM to join team!
Digital Sales Account Manager - Advertising Technology Business
- London
- £30,000 + bonus + benefits
Digital Sales Account Manager position at a world leading video, rich media and contextual advertising network.
Senior Voice Over Agent
- London
- competitive salary dependent on experience
Wise Buddah are looking for an experienced and passionate Senior Voice Agent to oversee our successful Voice Over roster.
Digital Account Executive – Creative Consumer Agency
- London
- up to £26,000
A well-known consumer PR consultancy is looking for a creative Digital Account Executive due to continued growth. Their client list makes for impressive read...
Sales Controller
- North West England
- £50000 - £60000 per annum + Car + 20% Bonus
Our client is a market and category leading Consumer Durables business with a very strong portfolio of successful brands, spanning multiple categories. As a ...
Global Business Development Manager - Top international Company!
- Bath
- Up to £70k DOE
We are on the hunt for a talented Business Development Manager with proven commercial experience within the professional services sector.
NEW BUSINESS MANAGER (Digital Media)
- Tunbridge Wells
- £45-50,000 basic plus comm OTE circa £60-75,000
Initiating, managing and developing client relationships at digital & brand strategy level in the Pharmaceutical & medical communications industry
SENIOR ACCOUNT MANAGER (Client Services)
- Tunbridge Wells
- £36,000-39,500 plus performance related bonuses (OTE £40k - £45k)
A client focused digital specialist & project manager, you know online and how to get the best from clients & colleagues to exceed expectation.
- City of London
- £30000 - £40000 per annum
THE ROLE Excellent opportunity for an experienced Business Development Manager to take a crucial role with a fresh London start-up agency.
Social Media Account Manager
- London
- up to £35,000
A well-known communications consultancy is looking for a creative Social Media Account Manager due to continued growth.
Business Development Director
- City of London
- £55000 - £60000 per annum + Bonus and benefits
My client is a global marketing services agency with offices across five continents and brand partners to a client roster that includes the worlds biggest co...
New Business Development Manager - Creative Agency - £15k to £20k OTE £30k to £35k
- Northants
- £15k to£20k with OTE £30k - £35k
My client is a well-established website and graphic design agency based in Northampton. They provide the complete range of creative design solutions for bran...
Head of Publishing Services
- London
- £65000 - £75000 per annum + +20%
Head of Publishing Services Major content and ad tech platform London to £75k + 20% My client is one of the biggest global digital platforms across deskt...
Corporate & Major Donor Fundraising Manager (Permanent) deadline for 14th March
- London Bridge
- £45,000
This position is responsible for leading the management and development of relationships and revenue from corporates and high level individuals.
Brand Manager
- Gatwick, West Sussex
- £Competitive + excellent benefits
Create engaging brand experiences for this stylish, innovative premium-quality coffee.
Assistant Brand Manager
- Gatwick, West Sussex
- £Competitive + excellent benefits
You're energised by tough challenges, creative brand-building…and great coffee.


text:
Hundreds stranded on snowy Long Island roads last night
At 1 p.m. Saturday, Jingo was still waiting.
"I would have been fine if I didn't have to swerve," he said.
On the expressway near Patchogue, dozens of cars, four-wheel-drive vehicles and even 18-wheelers were stranded along the snowy road. Some remained in their cars late Saturday morning, peeking out from time to time and running their cars intermittently to warm up as they waited for help.
In Middle Island, a Wal-Mart remained unofficially open long past midnight to accommodate more than two dozen people who were stranded on nearby roads.
"We're here to mind the store, but we can't let people freeze out there," manager Jerry Greek told Newsday.
Utility trucks, meanwhile, struggled to get around to restore power. About 10,000 homes and businesses, most in the eastern half of Long Island, did not have electricity Saturday morning, said Wendy Ladd of the National Grid.
"We have plenty of crews available to do the restoration work, and if we can get to them, we're saying we can get them back in 24 hours," Ladd said. "But the issue is whether our big trucks can get to them if streets aren't plowed."
Associated Press writers Mary Esch in Albany and AP radio correspondent Julie Walker in New York contributed to this report.
Copyright 2013 The Associated Press.


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The Intensive, Interactive, OR Business Management Conference is Here!
This conference is an opportunity for operating room (OR) business managers and directors to increase their knowledge of OR processes, develop ways to increase efficiencies in surgical services, and network with colleagues. Experts in managing the business of perioperative services will address topics such as the health care revenue cycle, supply chain, process improvement, and cost management.
The focus is on developing critical thinking skills as well as understanding cost components and overall financial management of the OR. During group breakout sessions, attendees will work on projects to hone their problem-solving and strategic planning skills. Topics to be covered include:
- OR charging methodology
- Vendor management
- Management of the revenue cycle
- Data management for decision making
- Operational efficiencies
- Value analysis process
- The role of the business manager
- And more!


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Tweet Cric Round 12 Winners- England v/s Ireland
TWEET CRIC..On day twelve,for England versus Ireland there were a total of 405 boundaries hit and 155 sixes...
The Prize for the Most fours goes to dj_dj11 for hitting 248 fours
The Prize for the Most sixes goes to Srikriti for hitting 83 Sixes
The best tweet prize also goes to Chintan2510 for the tweet ' Broad will help for Broad Win '
Congratulations to the winners!
Twitter Username | FourRCB | SixRCB |
Srikriti | 0 | 83 |
chintan2510 | 157 | 1 |
Aniket1001 | 0 | 69 |
dj_dj11 | 248 | 2 |
Latest comments
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Together with the Fan Advisory Board - They run all the activities, meetups and contests on RCB - on and off the Site.
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Book Description:"Introducing Statistics for Social Research" describes when to apply, and how to calculate, a wide selection of statistical procedures commonly used in the social sciences. Keeping statistical symbols and formulae to a minimum, and with simple examples, this book: assumes no previous knowledge of statistics of computing; includes a concise introduction to the program SPSS, with details of the different versions available; describes a wider range of tests than found in other introductory texts; and contains a comprehensive range of exercises with answers. "Introducing Statistics for Social Research" should provide an introductory statistics text for first- and second- year social science students. Duncan Cramer is also author of "Personality and Psychotherapy" (1991), and co-author, with Alan Bryman, of "Quantitative Data Analysis for Social Scientists" (1990).
Tags: Health, Mind & Body, Psychology & Counseling, General,
Book List () | College Textbooks
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a place for zinesters - writers and readers
October 5, 2008 from 2pm to 3pm – Super Picnic at the TINA zine fair Hello zine kids, Luke Sinclair, one of the coordinators of Sticky, is talking at TINA this year. The talk will be all about Sticky, how it started, how it manages to stay open, the highs, the lows,… Organized by Sticky Institute | Type: Zine, talk, zine, distro, shop
July 6, 2013 from 10am to 6pm – MIA Arts Center, KL The forth zine fest held in KL, Malaysia (i think)... Organized by nizang mosh | Type: zine, fest, and, distro, day
267 members
68 members
21 members
384 members
181 members
Ist preference given to distros and zines. Rates and details are here. Limited space. Very Low Cost!
© 2014 Created by Krissy PonyBoy Press. Powered by


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dc1000 is a program to control the Panasonic dc1000 series of digital cameras; it can be used to preview, download, and delete images. It supports the NV-DC1000, PV-DC1000, NV-DC1580, and PV-DC1580 camera models.
TimCam is a simple graphical Webcam program which captures pictures at intervals and intelligently uploads them to a specified FTP site. It is designed to be platform-independent.
A simple tool to manage encrypted storage.
A router live CD.


text:
- January 9, 2013
- 8:21 p.m.
- Suggest removal
- Reply to this post
bigmon writes:
If anyone views this pic. Take a good look to me it looks like a mini aerial view of the USA start with the lower left you have FL than to the right looks just like the curve of the Atlantic Coast line to the left the Gulf so on and so on
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Closing Time: Clay Buchholz dominant again, this time leading Red Sox past Blue Jays |
05.01.13 at 9:59 pm ET |
TORONTO 'Äď Clay Buchholz continues to take his game to new levels.
The Red Sox starter managed yet another standout performance, this time allowing just two hits and no runs, striking out eight and walking three in leading his team to a 10-1 win over the Blue Jays at Rogers Centre.
With the win, the righty became the first six-game winner in the majors while lowering his ERA to 1.01. Buchholz has the best ERA through the first six starts for a Red Sox pitcher since Roger Clemens in 1991 (0.73).
Buchholz, who has allowed a total of five earned runs in his six starts, also continued his domination at the home of the Jays. In 10 career starts at Rogers Centre, the righty has an ERA of 1.49, having led his team to wins in the pitcher's last eight appearances in the venue.
"Just very consistent," said Red Sox manager John Farrell regarding Buchholz, who becomes the first Sox starter since Josh Beckett to win his first six starts of the season. (Beckett won the first seven in 2007.) "Very poised on the mound. The maturity as we've talked about on a couple of occasions, continues to I think play out in those situations, where he's got to make a pitch with men on base. Once again, it was the case here tonight. Wasn't really challenged as he's been in other games. And that's not to take anything away from the Blue Jays, he was just in that kind of command from the get-go."
Offensively, Mike Napoli led the charge with the 11th multi-home run game of his career, hitting a solo shot to center in the fourth and a three-run job in the seventh. The second homer came on a 3-0 count, the fifth time in his career he has gone deep in such a situation. The first blast was measured at 472 feet, while the second came in at 467 feet. Both out-distanced Napoli's previous best of 460, hit earlier this season in Rogers Centre.
"It wouldn'Äôt matter to me, if it goes right over the fence, it'Äôs just the same thing to me," Napoli said. "It doesn'Äôt matter to me, but I thought the second one went farther."
Napoli and Stephen Drew both finished with three hits apiece, leading a 15-hit attack by the Sox.
Capping the scoring for the Red Sox was Mike Carp's solo, pinch-hit home run int he ninth inning. The blast remarkably gave the first baseman/outfielder 12 hits for the season, nine of which have gone for extra-bases.
"You go in there and you're in Big Papi's spot, so you better do some damage," said Carp, who was batting for David Ortz.
Here is what went right (and wrong) in the Red Sox' 19th win of the season:
- Drew got the scoring going with a two-run homer, his first as a member of the Red Sox. The second-inning blast, which sailed into the second deck, scored Will Middlebrooks, who had been hit by a Buerhle pitch. Drew came into the game with one hit in 14 at-bats against left-handed pitching. The Red Sox are now 13-0 when scoring first.
"I think the one thing that we've seen, we have to remember that probably on the homestand, compared to everyone else, was just about the end of spring training for him," Farrell said of Drew. "We're seeing the timing become more consistent. Right-handed and left-handed, he's still putting good ABs up and he's seeing the ball much better and he gives that bottom third of our order added depth and certainly a lift.
- Napoli'Äôs first homer 'Äď which helped him rebound from a four-strikeout performance Tuesday night — was followed by Daniel Nava'Äôs fifth homer of the season. It marked the fourth time this season the Red Sox have gone back-to-back (having done it twice against the Blue Jays). The Nava home run also marked the first home run by a Red Sox right fielder this season.
'ÄúI feel like I'Äôve been doing it long enough to understand that you can let those AB'Äôs go," the first baseman said. "Of course, you don'Äôt want to do that but you'Äôre not going to have a good night every night in baseball. I was able to let that go 'Äď I wish we had won and I did that, but we didn'Äôt. I know how to let things go and go to the next day.¬†I let it go. I'Äôll let this go, I had a good night, get out here tomorrow and do my same routine and try to have a good day."
- Ortiz extended his hit streak to 22 straight games thanks to a leadoff double in the sixth. He is the only major leaguer in history to accumulate a hit streak that long while playing exclusively at designated hitter.
- Will Middlebrooks not only came away with a pair of hits, but managed a nifty basket catch of Colby Rasmus' pop-up in foul ground in the sixth inning. It was Middlebrooks' third multi-hit performance in his last five games.
- Jonny Gomes, who came into the game 6-for-13 against Mark Buehrle, drove the Toronto starter from the game with his second walk of the game in the seventh. After Gomes scored via an Esmil Rogers wild-pitch, the lefty hurler closed out his line, having given up five runs on seven hits over 6 2/3 innings, raising his ERA to 6.43.
- Nava took advantage of a terrible baserunning decision by Melky Cabrera, who was thrown out by the Sox' right fielder trying to stretch his seventh-inning single into a double (down by eight runs). Nava's throw was right on the mark to Drew, who put on the tag with plenty of time to spare.
With one out in the sixth inning, the bases loaded and Buehrle's pitch count closing in on the century mark, Drew grounded into a 4-6-3 double play.
Alex Wilson had a rough outing in following up Buchholz, allowing one run on two hits while also issuing a walk.
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David Mann is a Managing Partner and Co-founder of Spring Mill Venture Partners, a venture capital firm focused on early-stage life sciences and information technology investments.
Previously, David worked with ServiceMaster Ventures, a corporate venture group, and was a founding member of the ServiceMaster Home Service Center, a high growth joint venture between Kleiner Perkins Caufield & Byers and ServiceMaster in which he held operations and sales roles. Earlier, he served as assistant to the Chief Executive Officer of INVESCO, a leading investment management company, while a summer associate.
David began his career as an officer in the United States Navy gaining operations, project management, and profit/loss experience. He was selected as a White House liaison assigned to the staff of the Secretary of the Navy. Earlier, David held various leadership positions in information systems as well as business operations and logistics on board a nuclear guided missile cruiser.
David received his Master in Business Administration from the Harvard Business School and his Bachelor of Science from the United States Naval Academy at Annapolis. He is an adjunct faculty member of venture capital and entrepreneurial finance at Indiana University, Kelley School of Business (Indianapolis). In addition, he has served as President and a board director of the Venture Club of Indiana, and serves as a Board Director of HVAF (Helping Homeless Veterans and Families) and on the Board of Advisors of the International Kidney Stone Institute, Indiana University Liberal Arts and Management Program, and Pellegrino & Associates. In addition, he is on the Naval Academy Nomination Committee for a United States Representative. Currently, David serves on the corporate boards of BioStorage Technologies, Cine-tal Systems, and WebLink International.
WebLink began in 1996 when our President and Founder DJ Muller realized that chambers of commerce and business associations were not taking advantage of the tremendous opportunity that the internet and websites gave them. WebLink's initial services included interactive business directories, real-time event calendars and website design and hosting services to help these organizations establish and build their brand on the web. Learn More.
Copyright WebLink International. All rights reserved. Contact Us | Email | Site Map


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Drug maker Perrigo has filed with the Food and Drug Administration for approval of a generic topical ointment for treating acne in adolescents and adults, the company said Wednesday.
Actavis hopes to become the first company to market a generic version of a drug used to treat acne in adolescents and adults, the company said.
A new treatment for bacterial infections of the vagina is now available, the drug's manufacturer said.
The Food and Drug Administration has approved an acne treatment made by Perrigo, the drug maker said Wednesday.
Mylan has completed its acquisition of two skin drugs from Valeant Pharmaceuticals, the generic drug maker said Monday.
A drug made by Coria Labs for treating acne now is available in a convenient, ready-to-use pump, the drug maker said Monday.


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SummaryIn Drosophila embryos, microtubules oriented along apical–basal directions support saltatory vesicle movement. Vesicle traffic includes lipid droplets whose distribution shifts twice during early embryogenesis. Using microscopy, optical tweezers, and a novel squashed-mount embryo preparation, we tracked single droplets and measured the forces these generated. Droplet stalling forces change developmentally, in a roughly quantized fashion, consistent with variation in the number of active motors. We characterized a mutation, klarsicht, that affects droplet transport. Klar+ facilitates changes in force, possibly by coordinating the activity of multiple motors. Alterations in transport affected motion in both apical and basal directions, indicating tight coupling between motors of opposite polarity. Mutations in klar also affect nuclear migration during eye development, suggesting multiple roles for klar-based transport.
Summary | Full Text | PDF (300 kb) - Measuring Molecular Motor Forces In Vivo: Implications for Tug-of-War Models of Bidirectional Transp...
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AbstractMolecular motor proteins use the energy released from ATP hydrolysis to generate force and haul cargoes along cytoskeletal filaments. Thus, measuring the force motors generate amounts to directly probing their function. We report on optical trapping methodology capable of making precise in vivo stall-force measurements of individual cargoes hauled by molecular motors in their native environment. Despite routine measurement of motor forces in vitro, performing and calibrating such measurements in vivo has been challenging. We describe the methodology recently developed to overcome these difficulties, and used to measure stall forces of both kinesin-1 and cytoplasmic dynein-driven lipid droplets in Drosophila embryos. Critically, by measuring the cargo dynamics in the optical trap, we find that there is memory: it is more likely for a cargo to resume motion in the same direction—rather than reverse direction—after the motors transporting it detach from the microtubule under the force of the optical trap. This suggests that only motors of one polarity are active on the cargo at any instant in time and is not consistent with the tug-of-war models of bidirectional transport where both polarity motors can bind the microtubules at all times. We further use the optical trap to measure in vivo the detachment rates from microtubules of kinesin-1 and dynein-driven lipid droplets. Unlike what is commonly assumed, we find that dynein's but not kinesin's detachment time in vivo increases with opposing load. This suggests that dynein's interaction with microtubules behaves like a catch bond.
Abstract | Full Text | PDF (773 kb) - Counting Motors by Force
Counting Motors by Force
Cell, Volume 135, Issue 6, 12 December 2008, Pages 1000-1001
Daniel St Johnston
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Cell, Volume 135, Issue 6, 1098-1107, 12 December 2008
Add/View Comments (0)Consequences of Motor Copy Number on the Intracellular Transport of Kinesin-1-Driven Lipid Droplets
George T. Shubeita1, 4, 6, Susan L. Tran2, 3, 5, 6, Jing Xu1, Michael Vershinin1, Silvia Cermelli1, Sean L. Cotton3, Michael A. Welte2, 3, 5, 7, , and Steven P. Gross1, 7, ,
1 Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA 92697, USA
2 Department of Biology, University of Rochester, Rochester, NY 14627, USA
3 Department of Biology and Rosenstiel Medical Research Center, Brandeis University, Waltham, MA 02454, USA
Corresponding author
4 Present address: Center for Nonlinear Dynamics and Department of Physics, University of Texas at Austin, Austin, TX 78712, USA
5 Present address: Department of Biology, University of Rochester, Rochester, NY 14627, USA
6 These authors contributed equally to this work
7 These authors contributed equally to this work
- The microtubule motor kinesin-1 plays central roles in intracellular transport. It has been widely assumed that many cellular cargos are moved by multiple kinesins and that cargos with more motors move faster and for longer distances; concrete evidence, however, is sparse. Here we rigorously test these notions using lipid droplets in Drosophila embryos. We first employ antibody inhibition, genetics, biochemistry, and particle tracking to demonstrate that kinesin-1 mediates plus-end droplet motion. We then measure how variation in kinesin-1 expression affects the forces driving individual droplets and estimate the number of kinesins actively engaged per droplet. Unlike in vitro, increased motor number results in neither longer travel distances nor higher velocities. Our data suggest that cargos in vivo can simultaneously engage multiple kinesins and that transport properties are largely unaffected by variation in motor number. Apparently, higher-order regulatory mechanisms rather than motor number per se dominate cargo transport in vivo.


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After the group successfully launched their new blog and campaign to end street harassment, Hollaback Appalachian Ohio! got straight to work designing a new educational program to encourage bystander intervention from area bartenders. They hope to train and certify at least 5 area bars over the course of the summer. Bar staff will need to attend one three hour training that discusses rape culture, bystander intervention, and self defense techniques and uses scenarios and activities to practice newly learned skills. A discussion group comprised of staff from all participating bars will follow two months later in order to discuss changes and progress made as well as how to move forward into the next school year. Bar tenders will then be able to utilize the blog to publicly report their brave and compassionate acts of bystander intervention as they test out their new skills through real life events. Participating bars will receive a window sticker bearing the Hollaback! Logo and the words, "This Establishment is I GOT YOUR BACK Certified," lending a sense of safety to patrons in that they can expect that someone will have their back should a tricky situation arise whether it be late into a drunken night out or just sipping one drink during happy hour. Participating establishments will also be listed in Hollaback! Ads in the papers thanking them for their participation.
Sarah Fick, Program Coordinator for the Sexual Assault Prevention Program and organizer for Hollaback Appalachian Ohio! had this to say about the new certification program, "We're going to ground zero. Street harassment is a huge problem in Athens, just like it is throughout the world. I've been avoiding going uptown during certain hours for years because the amount of harassment I have experienced from drunken college boys is obscene and extremely aggravating. We're doing something positive to change that. Bar tenders see it day in and day out, and we'd like to empower them with the knowledge of effective skills with which to safely challenge bad behavior. If bar patrons know that someone has their eyes open and is ready to intervene, they may be less likely to behave in a sexist or threatening manner in the first place."
Hollaback Appalachian Ohio! asserts that street harassment is part of rape culture, that living in a culture where inappropriate, intimidating, and disrespectful behaviors that cross personal boundaries are consistently allowed to happen in public spaces facilitates a culture where even worse things happen behind closed doors. They are working to change that culture, and they hope you'll join them. For more information about the certification program or to find out how you can get involved, email us at firstname.lastname@example.com.
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[...] Appalachian Ohio launched a bystander intervention certification program for area bartenders! Check out their great [...]


text: Need a quick facelift for an outdated bathroom? Nate says all you need is a fresh coat of paint and an easy hardware update. "One of the things that people at home can learn from is that we can freshen up this stuff without really doing a gut renovation," Nate says. Zigi and Yusef's three bathrooms look brand new after Nate adds new hardware, paint, white towels, a shower rod, a shower liner, shower rings and two medicine cabinets. The grand total? $250 for all three bathrooms! |


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Police: 1 dead, 1 critical in Little Village shooting
SUN-TIMES MEDIA WIRE June 30, 2012 4:40AM
One man was killed and another was critically wounded early Saturday in a shooting in the Southwest Side Little Village neighborhood, police said.
About 2:43 a.m., the two men, ages 33 and 42, were found shot multiple times in a vehicle that had struck a tree in the 2500 block of South Kildare Avenue, police said.
The 33-year-old was dead at the scene, and the 42-year-old was taken to Mount Sinai Hospital in critical condition, according to police.
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Cedarberry Cottage
Travel Blogs from Eureka Springs
Day 2 with Marc and Family
... on the Cassville Greenway.
Went over to Marc and Pam's around 3 for another fast paced evening with the Grand Kids. Only captured a few photos again today. It is hard getting anyone to stand still for more than 30 seconds. Had a wonderful time watching the grand kids and talking with Pam and Marc. ...
Traveled to my son Marc's today.
Today was my travel day from Wichita to Cassville Missouri, where my youngest boy lives. It was hard to leave Robin and her family because we had such a wonderful time while I was there. I am looking forward to seeing them again very soon.
After getting my truck and trailer ready to move, I joined Robin, Brittany, Kaden, Sydnie and Drennan for ...
Our Apartment!
... Arkansas region; this area is one of the fastest growing areas in the U.S. and is the H.Q. for Walmart and Tyson Chicken (two big companies, obviously). I think Walmart is HQ in Bentonville, which is just 10 minutes north of us, and Tyson is in Springdale, which is just South of us about 15 or 20 minutes.
Brad saw this area while we were still in China and noticed that it has very good access to transportation (major interstates, regional air-ports, ...
Happy Feast Day!
Late have I loved you, O Beauty ever ancient, ever new, late have I loved you! You were within me, but I was outside, and it was there that I searched for you. In my unloveliness I plunged into the lovely things which you created. You were with me, but I was not with you. Created things kept me from you; yet if they had not been in you the would not have been at all. ...
(And you assumed I couldn't pass up the pun to title this 'Eureka!' didn't you?)
Architectural gems can show up in the oddest places – think Fallingwater in rural western Pennsylvania – so it didn't surprise me that a beautiful wood, stone and glass chapel would show up in a forest in northern Arkansas. Thorncrown Chapel has been on my radar for years, but I never thought ...
Other places to stay in Eureka Springs
Red Bud Manor
7 Kingshighway, Eureka Springs | 3 star b&bfrom $112 -
Land O Nod Inn
109 Huntsville Rd, Eureka Springs | 2 star b&bfrom $96 -
All Seasons Inn
156 Spring Street, Eureka Springs | B&Bfrom $95 -
Turpentine Creek Wildlife Refuge BB
239 Turpentine Creek Lane, Eureka Springs | B&Bfrom $150 -
Pond Mountain Lodge and Resort
1218 Highway 23 South, Eureka Springs | B&Bfrom $100 -
Benton Place Inn
32 Benton, Eureka Springs | B&Bfrom $135 -
Hidden Springs Bed and Breakfast
23 Hillside Ave, Eureka Springs | 4 star b&bfrom $110 -
Belladonna Cottage
12 Echols, Eureka Springs | B&Bfrom $125 -
Daffodil Cottage at All Seasons Luxury Properties
156 Spring Street, Eureka Springs | B&Bfrom $90 -
The Pearl Tatman House
256 Spring Street, Eureka Springs | B&B -
Elmwood House
110 Spring St, Eureka Springs | B&Bfrom $119 -
Texaco Bungalow
77 Mountain Street, Eureka Springs | B&B -
Cobbler's Cottage
98 South Main , Eureka Springs | B&Bfrom $115 -
Apple Annie's Country Cottage and Bed and Breakfast
229 CR 3012 Greenwood Hollow Road, Eureka Springs | B&B -
Sleepy Hollow Inn
92 South Main, Eureka Springs | B&Bfrom $128 -
Angel Falls Bed and Breakfast
259 Greenwood Hollow Road, Eureka Springs | B&Bfrom $99 -
Ellis House at Trails End
1 Wheeler, Eureka Springs | B&B -
The Carriage Inn at Busch Mountain
20856 Highway 62 West, Eureka Springs | B&Bfrom $70 -
Anderson Acres Bed And Breakfast
3889 Mundell Road, Eureka Springs | B&Bfrom $105 -
Dr. R.G. Floyd House
246 Spring Street, Eureka Springs | B&B -
Four Winds Cottage
3 Echols, Eureka Springs | B&B -
Gardener's Cottage
C/O 11 Singleton, Eureka Springs | B&Bfrom $95 -
Maple Leaf Inn
#6 Kingshighway, Eureka Springs | B&B -
Primrose Place
41 Steele St., Eureka Springs | B&B -
Beaver Lake Cottages
2865 Mundell Rd, Eureka Springs | B&Bfrom $105 -
66 Center Street
66 Center Street, Eureka Springs | B&Bfrom $109


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Colorful Condo
A busy executive wanted a colorful, yet serene, home. Bold art, rugs and colorful upholstery and paint were added to a vanilla condo in Austin, Texas.
Colorful Condo
Asian details combine with modern art, rug and window treatments. Splashes of red make for an warm and energetic work space.
Photo by www.harrellphoto,com
color — andrealh
Colorful Condo
A modern dining table and chairs combined with bold art and florals create a cheerful Breakfast Room/Dining Room.
Photo: www.harrellphoto,com
Center arrangement — cfuerte
Colorful Condo
The client wanted a blue bedroom and a restful retreat that still had some bold and rich details. Chocolate was added to the blue for depth and a play of textures keeps things interesting.
photo by: www.harrellphoto.com
color — andrealh
Colorful Condo
Close up shot of some accessories in the Study. The client loves color and contrast and this is evident in the grouping of items showcased here.
photo by: www.harrellphoto.com
Like — joyceraye
Colorful Condo
The client needed a space for four kids to hang out. Colorful and fun fabrics and rugs are featured. Chocolate was introduced to tie into the overall home color scheme as this space was open to multiple rooms upstairs.
Photo by www.harrellphoto.com
wall colour — dial13
Colorful Condo
This is a girl's bedroom that combines fresh lime with rich chocolate. The client's two nieces stay here when visiting. The leather bed houses a trundle. They each had a custom embroidered pillows, throws and pillow to lounge with and wall shelves to display personal items and photographs.
photo: www.harrellphoto.com
repisa — andrealh
rug — nettandee


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Family, friends and fans said goodbye to football great Junior Seau. He committed suicide on May 2 at his California home. He played in the NFL for 20 seasons, for the San Diego Chargers, Miami Dolphins and New England Patriots.
The first kickoff is months away, but all eyes are focused on New York City as the 2012 NFL Draft begins Thursday night.
It's Victoria Beckham's birthday, and in honor of her big day, we're sharing some of her sweetest moments with her kids. Take a look in today's PopSugar Rush!
Check out some of the past week's top headlines from the entertainment world.
The crack of the bat, the smell of freshly cut grass, the taste of beer and peanuts. They can mean only one thing - the start of the MLB season. Take a look at the festivities and pomp and circumstance that helped usher in Major League Baseball in 2012.
Imagine seeing a naked guy running through your neighborhood. Fox News reports, "A man was speeding through an Ohio neighborhood when he hits a curb, sending his truck flying through the air. The vehicle slams into a porch and landing on a parked car." But that's definitely not the most ...
Actor George Clooney visited Washington, D.C. where he testified before a Senate committee, attended a White House State Dinner for British Prime Minister David Cameron and protested outside the Sudanese embassy. He was later arrested for trespassing on private property.
A Portland couple sued Legacy Health, which did prenatal tests on the mother, after their daughter was born with Down syndrome.


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I can't believe I found you
You help me when i'm down
Make me feel like i'm important
Your smile melts my heart
You laugh at my jokes
We make such a great couple
Taking care of each other
Helping and sharing our life
I feel I have always known you
My heart is yours
I love you with all my heart
You tell me the same
I know I have found my soulmate
The one and only for me
I promise with our wedding vows
To love honor and care for you
I have found the one
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This is a soft, semi-sheer, silk kimono. Beautiful colors. Matching tie-belt included.
One Size fits most 70% Silk, 30% Rayon See info page for international shipping procedure and costs.
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FREE SHIPPING ON WEB ORDERS OVER $100! *Some Exclusions Apply.
LOW PRICE PROMISE Se Habla Espanol! 678.510.0032
The EC-1118 strain is recommended for all types of wines, including sparkling, and late harvest wines and cider. It may also be used to restart stuck fermentations.
The fermentation characteristics of the EC-1118 — extremely low production of foam, volatile acid and hydrogen sulfide (H2S) — make this strain an excellent choice. This strain ferments well over a very wide temperature range, from 10° to 30°C (50° to 86°F) and demonstrates high osmotic and alcohol tolerance. Good flocculation with compact lees and a relatively neutral flavor and aroma contribution are also properties of the EC-1118. 5 gram packet good for 5 gallons.
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ChanandlerBong - 9:35 pm on Feb 22, 2013 (gmt 0)
as Votrechien's story amply illustrates, some people are jerks. Quite a lot of people are freeloading jerks actually.
Some of them end up as buyers on the net.
Some of them end up as vendors on the net.
and the world continues to spin. :)


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Whooping cough is a very contagious cough illness. It is spread through droplets from the mouth and nose when a person with pertussis coughs, sneezes, or talks. Young infants are at highest risk for severe illness, hospitalization and death from whooping cough.
Whooping cough vaccine prevents disease and saves lives. Before routine childhood whooping cough vaccination there were on average over 200,000 cases of whooping cough and 4,000 deaths EACH YEAR in the US. Whooping cough cases and deaths have been reduced by over 90% through widespread use of routine whooping cough vaccination. Despite this success, whooping cough has not been eliminated and has been increasing in recent years, reminding us of the importance of keeping vaccination rates up.
Be sure all children, teens & adults are up-to-date with whooping cough vaccine. Older children, teens and adults who aren''t up-to-date on their vaccine can spread the infection to infants, pregnant women and others.
Talk to your health care provider to make sure your whooping cough vaccine is up-to-date. Many local pharmacies also offer whooping cough vaccine.