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CELTIC manager Neil Lennon has revealed how he leant on the knowledge of Fabio Capello and Roy Hodgson last week as he puts together his plan to knock Juventus out of the Champions League.
NEIL LENNON has enlisted the help of the last two England managers as he tries to plot the downfall of Juventus in the
Champions League.
And he is determined to have top scorer Gary Hooper in his line-up to do it – after being angered by a £5million Norwich bid he believes has been engineered to unsettle his striker.
The Celtic boss used this week's League Manager's Association conference at the FA's new St George's Park complex to quiz Fabio Capello and Roy Hodgson about potential weaknesses in the Serie A giants' armoury.
And Lennon revealed Capello – a former Juve player and boss – believes Celtic should not be written off in the last-16 showdown.
He said: "Fabio Capello was there and was complimentary about us. He gave me a few titbits on Juventus.
"I'm not going to give too much away but he thinks we have half a chance. Roy Hodgson was very good with me on that one as well.
"It was great just to mix with these guys."
Celtic rejected Norwich's bid for Hooper immediately and Lennon wants the striker, who has been offered a new deal 18 months before the end of his contract, to stay at Parkhead.
He added: "Norwich made a bid and we rejected it. I'm annoyed it has come out down there because we like to do business privately.
"I don't like the thought of them trying to unsettle a player.
"Now I'm not going to point any fingers but it certainly hasn't come out from up here.
"I spoke to Gary's representatives today and we've made our position clear. We've made an offer to them and we're waiting back to hear from them.
"Norwich's valuation is nowhere near ours.
"Gary's not unsettled at all. His take on it is that he wants to stay, he wants to play in the Champions League and to have a go in all the competitions we're in.
"But we can't stop bids coming in, we can't stop speculation.
"Everyone has their price. I've maintained that all along.
"But Gary knows what we think of him, the club has made it clear to Norwich their valuation is not acceptable.
"I saw his agent here this morning. Gary's playing well, he's happy and we'll see if they come back and accept our contract offer.
"But we've made our position clear – we don't want to sell him."
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Volume 67 Received 6 May 2011 | 1-(9H-Carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol hemihydrate: a carvedilol solvatomorph Fernando Díaz,a Andrés Benassi,a Mariano Quintero,a Griselda Polla,a Eleonora Freirea,b* and Ricardo Baggioa* aGerencia de Investigación y Aplicaciones, Centro Atómico Constituyentes, Comisión Nacional de Energía Atómica, Buenos Aires, Argentina, and bCONICET, Buenos Aires, Argentina In the title racemic hemihydrated solvatomorph of carvedilol (carv), C24H26N2O4·0.5H2O, the asymmetric unit contains two independent organic moieties and one water molecule. Within this 2(carv)·H2O unit, the molecular components are strongly linked by hydrogen bonds and the unit acts as the basic building block for the crystal structure. Interactions parallel to (10) generate hydrogen-bonded layers which are further linked by much weaker C-HN/O interactions. The conformations of the organic molecules, as well as the hydrogen-bonding interactions connecting them, are compared with other related structures in the literature. |
Carvedilol is a drug indicated for use in the treatment of mild-to-moderate congestive heart failure, acting both as a 1/2-blocker and as an 1-blocker. It counteracts the (sometimes undesirable) effect of natural norepinephrine, a drug/hormone produced in the human body which by binding to the 1- and 2-adrenergic receptors (Stafylas & Sarafidis, 2008) stimulates the nerves controlling the muscles of the heart, and by binding to the 1-adrenergic receptors on blood vessels causes them to constrict and thus raise blood pressure (Othman et al., 2007). Through a blocking action towards these receptors, carvedilol lowers blood pressure and reduces heart failure.
There are at present five reported structures containing some form of carvedilol (carv): two of them are different polymorphs of the carvedilol free base [(II) (Chen et al., 1998) and (III) (Yathirajan et al., 2007)], two others are phosphate salts of the protonated carvH+ cation [carvH+·H2PO4-·0.5H2O, (IV) (Chernyshev et al., 2009), and carvH+·H2PO4-·C3H8O, (V) (Chernyshev et al., 2010)], and the fifth structure is a copper complex with carvedilol acting as a mono-deprotonated ligand {[Cu(carv)Cl(MeOH)]2·4MeOH, (VI); Zoroddu et al., 2003}. We report here a hemihydrated form of the drug, namely 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol hemihydrate, (I), where two independent carvedilol molecules (labelled A and B) share a single water molecule, itself a key component in the crystal structure organization, as discussed below.
The compound crystallizes as a racemate in the centrosymmetric space group P21/n (Fig. 1). The two independent carvedilol molecules have internal distances and angles quite similar to each other and to those of the previously reported examples. Similarities include the presence in both molecules of an O atom (O1) disordered over two sites on the host C atom (C21), with one configuration clearly dominant (see Refinement section for details).
In spite of their metric similarities, the conformations of molecules A and B in (I) are quite different, even though both central chains are essentially planar and the lateral aromatic side groups are structurally similar. The differences arise at the ends of the central chain, where the carbazole system and the MeOC6H4- groups are attached; it is here that the torsion angles defining the three-dimensional molecular structure show significant differences (Table 2, entries 1-2). Fig. 2(a) presents a combined view of both molecules after a least-squares fit of their `skeletal spine' [atoms C11-C21(O1)-C31-N2-C13-C23]; the way in which the side wings depart from each other is apparent.
But this behaviour is not exclusive to molecules A and B in (I); a very similar behaviour can be observed in the remaining noncoordinated carvedilol molecules/ions [(II)-(V)] mentioned above. All of them present a rather planar aliphatic central chain, as shown by the torsion angles involving the constituent atoms (Table 1, entries 3-5), differing by just a few degrees from a perfect antiperiplanar local conformation [with the sole exception of C11-C21-C31-N1 for compound (V)]. This can be seen in Fig. 2(b), where a similar fit as in Fig. 2(a) is shown, but performed on all six molecular units. Fig. 2(a) clearly shows the variety of conformations attainable through the combination of the rather low energy barrier to rotation in the aliphatic chain and the highly interactive character of both aromatic ends (the carbazole group, via its donor N92-H92 group, and the MeOC6H4- unit through its O1 acceptor). In the case of (I), this latter tendency is enhanced by the presence of a highly active water molecule, which is a determinant in the final packing of the structure.
Table 2 presents numerical values for the most significant hydrogen bonds in the structure and Fig. 1 displays all those in which O1W takes part. The water molecule acts as a double donor-double acceptor (Table 2, entries 1-2 and 3-4, respectively). The water molecule is attached to carvedilol molecule A through hydrogen bonds 1 and 2, giving rise to an R22(10) ring (Bernstein et al., 1995). The third hydrogen bond links independent carvedilol molecules A and B into a strongly bound 2(carv)·H2O unit. Finally, the remaining hydrogen bond accepted by O1W (Table 2, entry 4, and Fig. 1) links these three-component units into zigzag chains parallel to [010] (Fig. 3).
There are two further conventional hydrogen bonds in the structure of (I) (Table 2, entries 5-6), which link ribbons together along [101] and define broad planes parallel to (10). Strikingly, neither of the N1A-H1AN or N92B-H92B groups is involved in hydrogen-bonding interactions: interplanar linkage is achieved through much weaker C-HN/O contacts and no significant - interactions could be detected in the structure. The resulting packing scheme is schematically depicted in Fig. 3, where some of these planes (in different shading) are seen down b, with their projected image running along [101].
As a final remark about which are the leading sites for hydrogen bonding in carvedilol, in unsolvated polymorphs (II) and (III) there are two direct contacts joining adjacent molecules with each other and giving rise to characteristic two-dimensional structures. These interactions, of the hydroxy-amine O-HN and carbazole-methoxy N-HO types, are quite similar in both unsolvated structures, in spite of circumstancial differences in the unit cell, the atomic conformation and the packing disposition, as shown in Yathirajan et al. (2007).
In the present hemihydrated form, (I), there are instead four hydrogen bonds connecting adjacent A and B molecules, but this is a deceiving difference: a closer look shows that, in fact, the single hydration water molecule can be considered as only an intermediate step in a more complex set-up of the same type of interactions. The scheme below shows the way in which this is achieved, and how the same bonding scheme can be envisioned by just thinking of the interactions involving O1W-H1WA/B as `transparent'. Thus, the water molecule would not play any genuine interacting role but `propagates' instead the leading interactions, generated by the same participants as in (II) and (III). This is only one of the many roles that hydration water molecules can play in crystal structures; a very detailed analysis (for the particular case of inorganic/geological compounds, but readily extendable to any general case) can be found in Hawthorne (1992).
| Figure 1 The molecular structure of (I), showing the atom-labelling scheme and with displacement ellipsoids drawn at the 30% probability level. Only the major component of disordered atoms O1A/B and the H atoms involved in hydrogen bonds are shown. Hydrogen bonds are indicated by dashed lines. [Symmetry code: (i) -x + , y - , -z + .] |
| Figure 2 (a) The overlap of the two independent molecules (A and B) in (I), after a least-squares fit of their `skeletal spine', viz. C11-C21(O1)-C31-N2-C13-C23. (b) The same as for (a) but performed with the remaining carvedilol structures available in the literature. [See Comment for definitions of structures (II), (III), (IV) and (V).] |
| Figure 3 A packing diagram for (I), viewed down the [010] chains (coming out of the plane, and marked with a square bracket), showing in projection the broad hydrogen-bonded (10) planes (drawn in alternate shading). H atoms bonded to C atoms have been omitted for clarity. |
The original material, kindly provided by Laboratorios Quesada Farmacéutica, was dissolved in chloroform and the solution was left to slowly concentrate at ambient temperature in air. After one week, well developed single crystals in the form of rhomboidal plates, suitable for X-ray diffraction, were obtained. Since no particular effort was made to have a water-free solvent nor to inhibit air/moisture from getting into the solution, the reasons for the presence of a solvation water molecule may be multiple. A thermogravimetric experiment in the temperature range 300-600 K showed a diffuse mass loss in the range 340-370 K (mass loss found = 2.26%; expected mass loss for 0.5H2O = 2.17%).
In both independent molecules, atom O1 attached to C21 appears split over two sites, but with different occupancies, viz. 0.873 (3):0.127 (3) in molecule A and 0.821 (3):0.179 (3) in molecule B. This disorder is thus configurational, with both moieties in the selected asymmetric unit having the S configuration for the major fraction. The split O atoms were restrained to have similar C-O distances within a tolerance of 0.001 Å and constrained to have the same anisotropic displacement parameters [SADI and EADP instructions in SHELXL97 (Sheldrick, 2008)]. All the H atoms (except those attached to O1A' and O1B', which consequently were not included in the model) were found in a difference Fourier map. Those attached to C atoms were placed at calculated positions (aromatic C-H = 0.93 Å, methine and methylene C-H = 0.97 Å and methyl C-H = 0.96 Å) and were allowed to ride on their parent atom. Those attached to O and N atoms were refined for a further few cycles with restrained O-H = N-H = 0.90 (1) Å distances, and left to ride afterwards. In all cases, displacement parameters were taken as Uiso(H) = kUeq(carrier), where k = 1.5 for the methyl groups and 1.2 for all other H atoms.
Data collection: CrysAlis PRO (Oxford Diffraction, 2009); cell refinement: CrysAlis PRO; data reduction: CrysAlis PRO; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: SHELXL97 and PLATON (Spek, 2009).
Supplementary data for this paper are available from the IUCr electronic archives (Reference: GD3393 ). Services for accessing these data are described at the back of the journal.
Laboratorios Quesada Farmacéutica is gratefully acknowledged for providing the original carvedilol material. We also acknowledge ANPCyT (project PME 01113) for the purchase of a CCD diffractometer and the Spanish Research Council (CSIC) for providing us with a free-of-charge license to the Cambridge Structural Database (Allen, 2002).
Allen, F. H. (2002). Acta Cryst. B58, 380-388.
Bernstein, J., Davis, R. E., Shimoni, L. & Chang, N.-L. (1995). Angew. Chem. Int. Ed. Engl. 34, 1555-1573.
Chen, W.-M., Zeng, L.-M., Yu, K.-B. & Xu, J.-H. (1998). Jiegou Huaxue (Chin. J. Struct. Chem.), 17, 325-328.
Chernyshev, V. V., Kukushkin, S. Y. & Velikodny, Y. A. (2010). Acta Cryst. E66, o613.
Chernyshev, V. V., Machula, A. A., Kukushkin, S. Y. & Velikodny, Y. A. (2009). Acta Cryst. E65, o2020-o2021.
Hawthorne, F. C. (1992). Z. Kristallogr. 201, 183-206.
Othman, A. A., Tenero, D. M., Boyle, D. A., Eddington, N. D. & Fossler, M. J. (2007). The AAPS J. 9, E208-E218.
Oxford Diffraction (2009). CrysAlis PRO. Oxford Diffraction Ltd, Yarnton, Oxfordshire, England.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.
Spek, A. L. (2009). Acta Cryst. D65, 148-155.
Stafylas, P. C. & Sarafidis, P. A. (2008). Vasc. Health Risk Manage. 4, 23-30.
Yathirajan, H. S., Bindya, S., Sreevidya, T. V., Narayana, B. & Bolte, M. (2007). Acta Cryst. E63, o542-o544.
Zoroddu, M. A., Grepioni, F. & Franconi, F. (2003). J. Inorg. Biochem. 95, 315-320.

subset: commoncrawl


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Workshop on canine distemper to be held
Pruthvi R and Sukriti S email@example.com"A dog is a man's companion. Dog needs no charity but love and attention," says Vileena, member, Animal Rehabilitation and Protection Force (ARPF).
The ARPF, Hyderabad, which was awarded 'The best green group' by Andhra Pradesh Environment Connect (APEC), aspires to bring the much needed change in our attitude to pet dogs. Project Fighter, an awareness campaign about canine distemper, instituted in the memory of a St Bernard puppy which died of the disease recently will culminate in a workshop on Sunday.
Canine distemper is a highly contagious disease in dogs worldwide. This is not 100 per cent curable but is preventable. "Project Fighter aims at educating dog owners about canine distemper at the root level. Expert veterinarians will help the owners understand the importance of timeous vaccination and proper hygienic conditions for their pet's longer life. This will be the perfect platform where all the owners concerns regarding pets will be answered," says Nihar Parulekar, founder, ARPF.
"If you care about your pets, spare time to attend Project Fighter. This will help you prevent your pets developing the deadly virus," Parulekar pleads.
It was formed of dedicated and young animal lovers trying to prevent poaching of wildlife and rehabilitate disowned and injured pets. It has 300 members and service-minded veterinarians.
ARPF has been facing a shortage of funds and rescue shelters. ARPF has successfully rescued 30 snakes, 4 fawns, 2 squirrels, 12 puppies, 2 peacocks, 2 kites and 1 bat. Space has been a major problem. "Its good to see the youth coming up with such workshops," says Dr Jacob Mathews, a key member.
Category: City


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Vincent Anthony Clements Jr.
Position: RB
Height: 6-3 Weight: 210 lbs.
Born: January 4, 1949 in Southington, CT
College: Connecticut (school history)
Drafted by the Minnesota Vikings in the 4th round (102nd overall) of the 1971 NFL Draft.
Weighted Career AV (100-95-...): 7 (7983rd overall since 1950)
Output includes all passing, rushing, and receiving plays.


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The Future is Now
Join Date: May 2008
Location: Columbus, OH
Posts: 4,003
Re: If Dunn isn't signed long term, Jay Bruce needs a long term extension
I'd love to sign Adam Dunn long term nemesis. I've wanted them to do it since 2002. Every once in a while you need to take a shot. Go for the downs, swing for the fences, etc. They didn't do it with Dunn and now they're going to lose a valuable commodity. You can just tell when a guy is going to be a commodity. I could with Dunn and I can with Bruce. They don't come along often. It's ironic that their paths cross. Either one of them could be a face of this franchise, something we've lacked for a LONG LONG time, since Larkin in the early to mid 90's.
They've missed the boat on keeping Dunn. They need to take a chance and make Bruce the guy they build around. Solidify the main piece, then go and get everything else. Why is that so hard for Castellini and Company?
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Albuquerque Homeschool Forum / Introductions / Park Day
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847 (Guest), March 1, 2011, 10:41am
Where is the park at? We have been here a while but have not had a chance to go to Park Day yet! However, we are making it a point to come this Thursday. We need more interraction with others. Hope to see you Thursday.
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Beginning March 1, 2014 purchase your membership for next season and you can ski or snowboard the rest of this season for FREE! No more lift tickets. No more time limits.… Read more
Looking for something to do over March Break? Brimacombe will be open for skiing and snowboarding everyday over March Break, including Monday, March 10, 2014*. Better yet, all weekday lift tickets will be only $22+hst, even over the March Break!… Read more
Apres Ski Party Join us on the upper Floor of the East Chalet, for our monthly Apres Ski Event. Spend the night with friends, family and listen to live music from Sean Roberts in the warmth of the East Chalet. The dinner special will be a Gourmet Hotdogs with all the toppings imaginable for $5.… Read more
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Pay-per-click and affiliate marketing network Miva has hired an investment bank to explore and evaluate strategic options, including a potential sale of the company.
The company tapped Deutsche Bank Securities to help Miva's board of directors explore options that could include "the raising of capital through the sale of securities or assets of the company, a recapitalization, strategic acquisitions, and the combination, sale or merger of the business with another entity offering strategic opportunities for growth," according to a statement issued today.
"A sale is an option, but there are plenty of other options we're looking at too," Craig Pisaris-Henderson, Miva's chairman and CEO, told ClickZ News. "We're looking at a range of opportunities, the bottom line being to see how we can enhance or increase shareholder value. We've built these tremendous assets on a global basis, and we don't believe that value is being reflected in the marketplace."
One of the problems with the market's perception of Miva is that it is often compared to Google and Yahoo -- two consumer-facing companies that have a very different business model than Miva, Pisaris-Henderson said.
"We're not a consumer-facing search engine, we're an enabling monetization company. Our revenue model is very similar, but our business model is completely different than Google's or Yahoo's," he said. "We offer a sustainable advantage to anyone who has traffic to monetize, without being competitive to their business."
Another problem is the string of setbacks Miva experienced in the past year, including shareholder lawsuits, the sudden departure of its CFO and auditors, and a prolonged patent suit with Yahoo that was settled in August.
Pisaris-Henderson insists that Miva's problems are behind it, and said one of the goals of retaining Deutsche Bank is to make sure potential partners are aware of all that Miva has to offer. In the meantime, the company plans to continue business as usual, strengthening current relationships, adding new publisher partners and advertisers to its network, developing additional products, and maintaining client service.
The company's challenges are likely to continue, according to Safa Rashtchy, senior research analyst at Piper Jaffray. "The increased concentration of advertisers on Yahoo and Google -- and now possibly Microsoft -- combined with a decreasing market share for second-tier search sites makes Miva's business proposition very challenging in the current market," Rashtchy told ClickZ News.
Rumors have swirled around the company recently, as its stock has not performed up to expectations. In a November SEC filing, the company expanded from four to seven the number of company officers covered by its change-in-control plan that would take effect if Miva were to be bought, making executives' stock options immediately vest, ensuring they receive a year's severance pay upon termination, and prohibiting them from competing with Miva for one year.
Potential buyers for Miva include Yahoo, which could absorb Miva's advertisers and publishers into its Yahoo Publisher Network, or Microsoft, which could use Miva's base to jump-start its fledgling ad network. It's unlikely that there would be interest in individual parts of its business, given that the market already had its chance to acquire most of the parts before they were picked up by Miva, said Shar VanBoskirk, senior analyst at Forrester Research.
"Miva is an aggregation of several different previously independent search players, so I think the most likely future for them is an acquisition of them in total," VanBoskirk told ClickZ News. "I think Miva's most interesting functionality is its pay-per-call capability, which makes it a good fit for a Yellowpages.com. Another possible buyer could be a company in Europe based on Miva's strength there."
Meet Your Favorite ClickZ Contributors
Many of ClickZ's leading expert contributors will be at ClickZ Live, the new online and digital marketing event kicking off in New York (March 31-April 3). Hear from the likes of: Jeremy Hull, Lisa Raehsler, Andrew Goodman, Bryan Eisenberg, Mathew Sweezey, Aaron Kahlow, Stephanie Miller, Simms Jenkins, Jeanne S. Jennings, Dave Hendricks and more!
Kevin Newcomb joined ClickZ in August 2004, covering search marketing and other online marketing topics. He has been reporting on web-based businesses since 2000.
Before the bubble burst, Kevin was a marketing manager for an online computer reseller, handling copywriting, e-mail marketing, search marketing and running the affiliate program.
With a combination of real-world marketing experience and years of business journalism, Kevin brings to ClickZ a unique ability to deliver news and training materials that help online marketers do their jobs better.
March 18-19, 2014
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August 5-7, 2014
March 19, 2014
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Final - 11.14.2013 | 1 | 2 | 3 | Total |
Los Angeles Kings | 0 | 0 | 3 | 3 |
New York Islanders | 0 | 2 | 0 | 2 |
Thomas Vanek is not back and Daniel Alfredsson is also out, but no one cares because this is the first game the Islanders and Red Wings will play since Jack Capuano punked Mike Babcock with a timeout in a 5-1 win in 2012.
News and notes for New York islanders fans. Recaps of last night's blown game to the Kings, plus news of Thomas Vanek's return, Taylor Cammarata's start and another NHL suspension.
Islanders coach Jack Capuano and goalie Kevin Poulin were almost Zen-like in fielding questions after last night's loss. A missed opportunity, but a game against one of the Western Conference's best required at least some degree of perspective.
Tanner Pearson's first career goal ties the game in the third period, and Tyler Toffoli gets the winner with under two minutes left at Nassau Colisuem. Scrivens stops 23 shots in his first start since Quick's injury.
A player's first NHL goal, a teammate's rush to pick up the puck, the whole line's hockey hug to congratulate him...those are some of the cool things about hockey.
The New York Islanders held a 2-0 lead through two periods, then the Los Angeles Kings showed them who's boss.
Pearson joins Vey and Toffoli! Scrivens in goal! Martin Jones sitting on the bench!
The most important thing about tonight: John Tavares is OK. Banged up, but fine. That may mean the already physical Los Angeles Kings target him even more, but a lineup without him would look particularly ugly against one of the league's top teams.
Dunn digs some really old crap of his out of storage
The New York Islanders face the Los Angeles Kings at the Coliseum tonight, but it's different this time: No in-law jokes, this family is tearing itself apart.
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Teaching Plan | HBS Case Collection | October 2012
by Robert F. Higgins
This is the teaching note related to HBS case 808005. In 2001, Vertex Pharmaceuticals Incorporated acquired the San Diego-based biotech company, Aurora Biosciences. The combination of Vertex's and Aurora's technologies would improve the flow of novel drug candidates into development. However, several questions related to the integration of Aurora into Vertex were still unresolved, the most pressing being Aurora's major collaboration with the Cystic Fibrosis Foundation (CFF). Were venture philanthropy and foundation deals an appropriate funding mechanism for a public company like Vertex?
Keywords: venture philanthropy; biotechnology; funding philanthropy venture; venture capital; cystic fibrosis; foundations; Pharmaceuticals; Mergers and Acquisitions; For-Profit Firms; Venture Capital; Giving and Philanthropy; Science-Based Business; Nonprofit Organizations; Pharmaceutical Industry; Biotechnology Industry; United States; San Diego;
Higgins, Robert F. "Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech (TP)." Harvard Business School Teaching Plan 813-021, October 2012.
Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech (TP)
Robert F. Higgins
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Case | HBS Case Collection | October 2013
Steward Health Care System
Robert F. Higgins and Noah Fisher
Keywords: accountable care organization; ACO; Medicare; Medicaid; medical services; Cerberus; Caritas; health care policy; health care industry; provider organizations; Health Care and Treatment; Health Industry; United States;
Course Overview Note | August 2013 (Revised September 2013)
Entrepreneurship in Healthcare IT Services (EHITS) Fall Term 2013: Course Outline and Syllabus
Keywords: Healthcare Technology; health services; healthcare ventures; Entrepreneurship; Health Care and Treatment; Information Technology; Health Industry; Technology Industry; United States;
Case | HBS Case Collection | September 2013
Claritas Genomics
Robert F. Higgins and Matthew Preble
Keywords: Boston Children's Hospital; genetic engineering; genetics; genetically modified; genetics diagnostics; information technology; Information Management; health care industry; healthcare IT; Healthcare Technology; healthcare ventures; Biotechnology Industry; Biomedical Research; Patrice Milos; genomics; genomic testing; Life Technologies; Health Care and Treatment; Information Technology; Information Management; Genetics; Biotechnology Industry; Information Technology Industry; Health Industry; Boston; Massachusetts; United States;


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Mayhem #47741 Model
Here is what you may book me for: -Modeling -Makeup -Hair -Clothing Designer -Seamstress -Photographer -Fashion Show Producer -Event Coordinator ---------------------------------------------------- In the words of a great friend of mine: "TFP, no TFP, TFCD, etc. One way or another, someone's got to pay." - Oliver Mendoza I do very limited TFP, only because I find that there at so many people who enjoy wasting my time. Unless we are friends.. I don't just want to hangout with you.
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@Serene@Shiny Celebi@Sky Flame Haze@Smasher 101@Flame_@mewstone@TFSpock@Neonsands@Hadesiro@Nytie@The Puppetmaster@Derpeh Hoovez@bluesun
The townspeople gathered in the square, their eyes all shifting suspiciously from one to the other, though for varying reasons. A young woman spoke up, "The witch haunted me in my dreams again last night!" she screamed, her voice cracking as she shuddered in terror.
"You've brought this on us!" one man accused another.
"No, it was her!" another voice proclaimed.
The whole town descended into angry bickering and muttering amongst each other, it seemed no one could be trusted...
But then, a single voice rose above the rest.
"It was I!" a peculiar, frazzled man declared, stepping up on a tree stump to garner as much attention to himself as possible. "I am the hideous witch! So... um... gather all ye thine torches and thine pitchforks, so that ye mayest chase mine unholy self through the streets!" he proclaimed, an almost hopeful tone in his voice as he smiled in mock malevolence.
"Well... alright then!" the crowd replied.
Neonsands has been lynched.Originally Posted by Master MewNeonsands, you are...
James MacFay (Lunatic)
You are James MacFay, the local Lunatic. You are raving mad and love every minute of it. As a result, the idea of the citizens of Salem gathering pitchforks and torches and chasing you through the streets is a secret fantasy of yours, and one you wish very much to see fulfilled.
If targeted by the Coven during the Night Phase, YOU WILL NOT CONVERT and will be killed by the Coven to cover their tracks.
You are not aligned with the Citizens of Salem, nor are you a member of the Witch's Coven. You will win by being lynched by the citizens of Salem, but YOU ARE NOT ALLOWED TO ROLECLAIM (you don't know you're crazy). Being Nightkilled does not count toward your goal. Upon completion of your goal, you will be removed from the game and will share Victory with the winning Faction.
It is now Night 1, you have until 10/15/2011 @ 11:00 CST to submit your Night Actions.


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Man lands on moon!
Printable View
Sounds like the same classless turds that were cheering "let's go Hornets" when we were getting blown out by .... want to say the Spurs on a Saturday night game about a month ago. True class - this was somewhere over near the 229-230 seat area if my memory serves correctly.
Chanting "Char-lotte Horn-ets!!!" and "Bee-fense" at a Bobcats game is a disturbance. I wouldn't consider that cheering for the team. I would consider that cheering for a brand. It's disrespectful to the actual Bobcats fans at the games that are immune to the history of the Hornets franchise and what it meant, especially when the "Bring Back The Buzz" people are frowning upon and belittling anyone wearing Bobcats apparel.
Interesting thought I just had - What happens to this website/URL if the team changes names?
Stuff like this keeps me away from the games. I'm there to enjoy the team, I don't care about someone's beliefs or desires around me, I just want to enjoy a game and not get caught up in the "politics".
Ziggy owns the domain name Hornetsplanet.com so if the name changes we can still come here to argue about the good old days when we were the Bobcats.
I'm going to start a movement right now called Bring Back The Cats


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New single MADE IN AMERICA!!! http://t.co/MrvY77Xfi1 Member of CiMORELLi. Alpha Female//Princess///God is my #1. Never give up on your dreams.
Face Tags
Aaaaaaaaaaaaand another (:
From our photoshoot (:
Nick and I (:
@MayaCraze HERE ya goooooooooooo. Also, the last pic we twitpic-ed on @cimorelliband really shows the layerzzzzzzzzzz (:
My Fairy costume on Halloweeeeeeeeeenieee :D
ZOMBIE! First Halloween costume. More to come tomorrow............ :D
Prev 1 2 3 4
Twitpic supports an Open Internet. Join us in the fight against legislation like SOPA and PIPA.


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March 09, 2014
How often do you practise your short game? If you're like me probably not often enough. Is boredom part of the problem? Here are some short game tips from Ben
As there always is, the days leading up to this week's Masters tournament have been filled with all types of hoopla. You have the speculation over whether or not Tiger Woods is using a
Jim Neveau, TGW Columnist To paraphrase Wes Mantooth, Vince Vaughn's character in the film "Anchorman", today in Phoenix, Arizona, we spell redemption "K-Y-L-E". Kyle Stanley, a tragic figure last week at Torrey Pines when he imploded
It's been a long day, not a lot of time to write this evening. That said, I did want to comment on a few things. For the extended recap of Friday's action at the


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Argh! No CR in the women's 4x4
2 posts
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Argh! No CR in the women's 4x4Aw, I wanted it so bad and Texas got so close: 0.3 away from a new national record (they ran 3:26.76)! Oh well, it's still a hell of a way to finish the season. And a second-place team finish: What a nice reward for Bev Kearney after the horrible experience she went through this year. Great job, ladies!
Re: Argh! No CR in the women's 4x4Heck, everyone at the stadium wanted a CR too, but something got in the way: an amazing race!
Richards surely could've run faster, but she made sure she had plenty in reserve in the final straight.
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The following is a Plus Edition article written by and copyright by Dick Eastman.In an earlier article, I mentioned that I was planning to replace my aging and somewhat deaf GPS with a new model. I solicited suggestions and did receive quite a few worthwhile comments. However, in the end, I decided to purchase a different GPS from what had been suggested. The model I purchased is new, having been released by the manufacturer only a few weeks ago. It is so new that no newsletter readers had any experience with this particular model.
The device I purchased is quite different from any other GPS I have ever seen or used. For one thing, it is cheaper than most of the units I had previously considered. Next, it is smaller than most other GPS devices made for automobile use, which turns out to be a mixed blessing: some good, some bad. Finally, it has several features I have never seen on any other GPS unit. It has one feature that really excites me as I have another "secret weapon" that extends its capabilities.
The remainder of this article is for Plus Edition subscribers only.
If you have a Plus Edition user ID and password, you can read the full article right now at no additional charge in this web site's Plus Edition at http://eogn.com/wp/?p=11367. This article will remain online for several weeks.
If you do not remember your Plus Edition user ID or password, you can retrieve them at http://www.eogn.com/wp/ and click on "Forgot password?"
If you decide to subscribe to the Plus Edition right now, you will be able to immediately read this article online. What sort of articles can you read in the Plus Edition? Click here to find out.
For more information about subscribing to the Plus Edition of Eastman's Online Genealogy Newsletter, visit http://blog.eogn.com/eastmans_online_genealogy/plusedition.html.


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2010 Chevrolet Camaro 2 SS with RS package, car has 2600 miles on it. All pfadt suspenison, car is like new ,......orange stripes, auto.... More
2002 Chevrolet Camaro SS, Heavily modified 2002 Camaro SS. Original LS1 replaced with brand new all aluminum SLP LS2 402ci engine with all forged... More
2002 Camaro Berger SS #72 Phase II 435hp, 6 speed, 4.10 gears 9K original miles Built exclusively for racecar driver Johnny Benson, Jr. Production: 1 of 1 produced One of... More
1999 Chevrolet SS Camaro Convertible, LS1 V-8, Automatic, less than 23K original miles, 20/28 MPG, Black with Black convertible top, Gray/Black leather interior. Monsoon... More
GM Canada certifed 350 SS Camaro with 50,000 orignal miles. All numbers macthing and date code correct car, all numbers verifed and recorded. Protect... More
Car to be auctioned at the Speedway Collector Car Auction - April 3-5, 2014 at the Charlotte Motor Speedway 2011 Camaro Pace Car 864 Original Miles Car... More
2010 CAMARO SS LIKE NEW. LOADED Listing my good friends Camaro SS that is loaded with every available option from the factory . He is the... More
1969 Chevrolet Camaro 427 Big Block that has undergone a complete body on restoration and is rock solid from top to bottom! It is... More
1971 Chevrolet Camaro RS split bumper converted to Z28 recreation at the time of the restoration. It is powered by the 350 mildly built... More
*1969 CHEVY CAMARO* "THE ULTIMATE AMERICAN CLASSIC MUSCLE CAR" ... More
Brutally fast, this 1968 Camaro rocks a stroked small block, a built automatic, lots of chrome, and a sinister black-on-gray paint job that will... More
A rear opportunity to own one of a kind Rest Mod, multiple show winner, including Supper Chevy Magazine and prestigious Tremic award. 1968 Camaro... More
2010 Chevrolet Camaro RS/SS 547hp/530# Torque 6.2L SuperCharged V8. Silver with Black SS Stripes. Headers with 3" Exhaust System. Suspension Upgrade - PFADT Suspension... More
When it debuted in 1967, the Chevrolet Camaro was GM's answer to the Ford Mustang -- and the two automotive icons have remained locked... More
2002 Z28 SUPERSPORT CAMARO Presented for your pleasure is this 2002 Camaro in showroom condition. This car is unmolested. There are no after-market "speed" additions... More


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EFC Hosted Listservs
A listserv is a topical electronic forum where list subscribers may post announcements, participate in discussions and pose and answer questions. A listserver automatically distributes an e-mail message from one member of a list to all other members on that list.
The following listservs are supported and hosted by the EFC. Subscription is free, and you may join as many listservs as you wish. These listservs are maintained through the School of Government at the University of North Carolina. Click here to view a complete list of listservs maintained by the SOG.


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The source video can be encoded into virtually any format. Let's say it sits in ~/Videos/Test.webm
The end result is simply to stream the video, with sound, directly through a 'fake' video device, so it can be picked up by Google+ Hangouts.
The video was created with ffmpeg, and reading around forums and on this site, it seems that ffmpeg or ffserver can be used for this, but it's beyond me how to stream the video.


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Ok all you idiots out there...help for the tourney has arrived!
It is time to start to focus on March Madness!!! So based on USA Weekend's Brian Tucker's Article, I will give my own spin and call it The Idiot's Guide To The NCAA Tournament Office Pool! This will be a 5 part series, with a new blog everyday with a new rule! So imagine yourself at the water hole at work. All of a sudden that new guy runs up to your face and shoves a bracket and demands that he gets your picks in 5 days. Don't worry! Just follow Anthony E.'s Idiot Guide To The NCAA Tournament! (Not available in stores, but you can find it exclusively on the Complete Idiot's Guide to Sports Group for free!) and by the fifth day, you'll pick yourself a winner!
RULE #1: Never worry about the guy that shoved the bracket in your face. (In other words, the hoops expert in the office.)
There always seems to be that one hyper/wierd guy that knows everything and doesn't have a life unless its about NCAA Basketball. All season long, all you've heard from him is "mid-majors", "on the bubble", "great perimeter shooting", "the intangibles". He seems to know everything there is to know. He even knows how to spell "Krzyzweski" and sometimes uses it as a verb, or a pronoun, or as a way to shut that annoying guy up on the phone who calls on Mondays to ask if you're open every single week. But as much as he may know, just realize that this guy will NEVER. I said NEVER. HE WILL PROBABLY NEVER WIN THE POOL! The NCAA Tourney is all about the unpredictable, and there is no way that analysis can serve him to win. This guy has as much chance of predicting every game right as he does winning the German version of American Idol. Even if he knows German. So don't worry about or listen to this guy. You could literally guess blindfolded and have just as much of a chance to win then his carefully analyzed bracket. Trust me. I have seen it done.
So there you have it. Day 1 Rule 1. You are 1 step closer to picking a winner! Tune in tommorow, same place, to get Rule 2!!!
(In no way are these rules a guarantee that you will pick a winner. Nor that you will win any type of monetary reimbursement for your time and lack of effort in filling out those lines with names you probably never heard of. But since you probably are NCAA TOURNEY-handicapped, what better option do you have? So try the Idiot's Guide!)


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While Rio Tinto's executives bask in the friendly climes of London, Perth and Singapore, it's in Mongolia — one of the unforgiving lands where the it digs up its treasure — Rio has again orchestrated its own crisis.
READ MORE7 Results
New agreement confirms ANU/Mongolia language sharing
Last year the Australian National University offered students the opportunity to learn Mongolian from classes held at Indiana University, a program set to continue thanks to a recent agreement signed with the Mongolian Prime Minister, writes William Steed.
READ MOREMongolian nomadic way of life in deep freeze
Two decades after the collapse of communism, Mongolia may be on the verge of a new turning point following a devastating winter which destroyed a fifth of the nation's livestock. Mongolia may be saved, however, by its abundance of natural resources, writes Tania Branigan.
READ MOREPHOTO GALLERY: Mongolia's worst winter in 30 years
Beautiful but depressing images from Mongolia, where locals are enduring temperatures as low as -50 degrees Celsius and livestock are dying in the millions.
READ MOREPHOTO GALLERY: Family portraits of China's 56 ethnic groups
A beautiful gallery of families from China's many ethnic groups. The project's title of "Harmonious China" might cause some eye rolling, but it's a great visual guide to the myriad peoples and cultures currently annexed by the Chinese government, nonetheless.
READ MOREGFC hits Mongolia's herders
The impact of the Global Financial Crisis can be felt in even the most far-flung corners of the world, including Mongolia's grasslands, where plunging commodity prices have been disastrous for local sheep and goat herders.
READ MOREPHOTO GALLERY: A tale of two Mongolias
The independent nation of Mongolia and the Chinese-controlled Inner Mongolia may share a common history, but have taken two very different paths over the last 20 years. Stunning photos show neighbouring countries that are worlds apart.


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Eagerly anticipated each year in Myrtle Beach, the Art Museum's Annual Tour of Homes features an array of spectacular houses and the opportunity to enjoy a buffet luncheon with an ocean view at The Dunes Club.
Mickey Spillane Lecture Series
Reservations necessary, 843-238-2510
Wednesday, March 12, 2 p.m.
My Life with Mickey book signing and lecture with Jane Spillane
Wednesday, March 19, 2 p.m.
Kiss Me, Deadly (the book) presentation and discussion led by Dr. Daniel Turner of Coastal Carolina University
Wednesday, March 26, 2 p.m.
Kiss Me, Deadly (the film) screening and discussion led by author and Chautauqua institution lecturer on film, David Zinman.
Wednesday, April 2, 2 p.m.
The Athenaeum Press and My Life with Mickey: a conversation with The Athenaeum Press director Patricia O'Connor and CCU student Andrew Lesh
This exhibition will feature approximately 14 paintings by British artist Julyan Davis who has painted the South for more than 20 years and currently lives in Asheville, North Carolina.
This exhibition, produced by the Fiber Arts Guild of Pittsburgh, Pennsylvania, Inc. is the 21st juried exhibition of the best of contemporary fiber art. This exhibition will feature 37 of the 73 works by artists from all over the world.
The Art Museum's most recent acquisitions will be exhibited together for the first time, including works by Philip Mullen, Jim Harrison and Bill Jameson.
I, the Writer: A Collection of Mickey Spillane Memorabilia
Wednesday, March 12 - Sunday, April 20, 2014
Presented in conjunction with Coastal Carolina University's OLLI division and the Atheneum Press. Additional programming scheduled.
A Closer Look
$10 per girl scout
Ages 3 - 4
Bringing Leaves to Life
Free for members
$5 for non-members
Ages 5 - 7
Paint It Your Way
$10 for non-members
Ages 8 - 12


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You are viewing Underworld by Kaz on Mylittlefunny.com - 3 of 5 Happy Home By My Little Funny Kaz's infamous classic American comic strip "Underworld" is short, rude, and funny -... more »Kaz's infamous classic American comic strip "Underworld" is short, rude, and funny - but you won't find it in the daily newspapers because it might give someone's grandmother a heart attack! His comics have appeared in Raw Magazine, all 3 volumes of Little Lit, Nickelodeon magazine and etc. Kaz is also an award winning writer who has worked on successful animated television shows such as Spongebob Squarepants, Camp Laslo (Emmy 2009) and currently Phineas and Ferb. « less Published July 24, 2012 160 views More Info » Full Credits My Little Funny Uploader Additional Credits Additional Credits: Kaz Prapoulenis, Matt Campbell, Karl Wills, Chris Tsakis, Jon Spencer Stats & Data 5 Funny Votes 2 Die Votes 158 Views Published July 24, 2012 Categories: Animation Politics Kids Being Awesome Keywords: Funny Cartoon Underworld Kaz Funny Underworld Comics Raw Weirdo Popeye Underground Comics Mondo Animation Sidetrack Adult Human Bong AUTOPLAY Up Next In: 10 Mike Birbiglia's "Porno for Parents" Animated! The Somewhat Comical Adventures of Prickley Pete - Episode 1: Night of the Living Ascots Abe Kanan show Cartoon Episode 1 Little League These Are My Friends-Cartoon Test Short Follow Facebook Twitter Tumblr Instagram
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Saturday March 4 2006
« Why go out? | Home | Oscars party, right here »
Nigel Newton addresses the Guardian Review World Book Day forum
Nigel Newton, chief executive of Bloomsbury and chairman of the 2006 World Book Day, spoke on Thursday to a packed Guardian Newsroom about the challenges facing the publishing industry in the future, from the predations of Google Book Search to the dearth of young talent in the industry today. You can read an edited transcript of the speech in this week's Guardian Review, or click here to listen to his speech in full on your computer (MP3; 42). Alternatively, paste http://blogs.guardian.co.uk/culturevulture/podcast.xml into the Podcasts bit of iTunes or your RSS reader, to subscribe to the Culture Vulture feed and receive all the Vulture's podcasts as they become available.
Interesting site!!!
Perhaps you should have a quick look at mine.
Keep it up...
Offensive? Unsuitable? Report this comment.
Given the "dearth of young talent in the industry today" perhaps The Guardian should follow-up their Top 50 most influential list... with a Top 50 Literary Unknowns list to address the balance.
Just a thought.
Posted by HPT on March 10, 2006 1:46 PM.Offensive? Unsuitable? Report this comment.
Strange - I didn't see a transcript in the Review online or in print. Possibly just as well - his call for a Google boycott was full of the most incredibly misleading and misguided arguments about copyright I have heard in years...
Posted by David Brake on April 3, 2006 2:31 PM.Offensive? Unsuitable? Report this comment.
Let me see where to begin. What is wrong with Google Book indexing copyright books? What exactly is Google doing with Google Print? First, what *isn't* it doing? It isn't making copyrighted books available cover to cover against anyone's will. Google makes books available in their entirety only when the books are in the public domain, like Project Gutenberg has done for years.
Quoting a sentence or two from a book is fair use, I dont think any one disagrees with this so whats the problem?
Copyright law is designed to protect authors, yes, but it is supposed to do so in a balance with the public good.
Posted by Glyn Wintle on April 3, 2006 4:58 PM.Offensive? Unsuitable? Report this comment.
I am glad Mr Newton has detailed his views on Google Print as clearly as he has. Any doubts I may have had that the publishing industry is not mindlessly persuing profits at the expense of the artists they claim to support (not to mention the public domain they owe their exitance to) has now been thoroughly eradicated.
Posted by Jonathan on April 3, 2006 11:09 PM.Offensive? Unsuitable? Report this comment.
Offensive? Unsuitable? Report this comment.
Latest from Culture Vulture
- And that's a wrap...
The Guardian Unlimited Music team is home or on its way home. For a round-up of the weekend, visit our Glastonbury special report. For all the reviews from this weekend - the Who and the Kaiser Chiefs have been added,... - Mark Ronson: awesome
So saith Betty Clarke in her review.GlastonburyGlastonbury 2007Festivalsguardian.co.uk © Guardian News & Media Limited 2009 | Use of this content is subject to our Terms & Conditions | More Feeds... - Pump up the Bassey
Dame Shirley shows the Arctic Monkeys how it's done. Photograph: Carl de Souza/AFP/GettyAlex Needham gives Shirley Bassey - and her full orchestra - nine out of 10.Meanwhile, on the music blog, Hard-Fi tells us why they're playing Glastonbury even...
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Recently reduced! Must sell!
This contemporary set includes a table (36″ × 60″) with a 12" removable leaf, four chairs, and three 30", swivel-base bar stools. Color is "honey".
Made of solid Canadian birch, with a baked on finish; extremely durable.
This classy dining set is in excellent condition; perfect for a family.
Will sell table and 4 chairs separately for $400; barstools for $75 each.
Entire set (8 pcs.) for $495.


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Cisco Systems: Highlights of Sheriff Lee Baca & Connie Rice Super Session - Gangs in Los Angeles |
Check out video highlights of Sheriff Lee Baca, Los Angeles County, and Connie Rice, Co-Director, Advancement Project, talking at the Cisco Systems Super Session about changing the paradigm in dealing with gangs. Filmed at the IACP 2008 law enforcement tradeshow.
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Результаты первого дня
Зона А Зона B Зона C Зона D Зона E Командный зачет первого дня
Отчет Первого дня Saturday 15th September.... Paris by David Ewing
The first day of this World Champs is now over and what a cracker it has been. Not a cracker in terms of the fish caught but in terms of how tight and technical a match it has turned out to be. Interestingly, of the top 10 teams, 7 are from the former Eastern Block, but the first four - Italy and Yugoslavia both on 41.5 points, France 45 and England 49 leave no doubt that tommorrow is a three horse race. The fishing today was hard - as expected - but not a lottery. there were two ways to catch for most teams, one was roach fishing on the bottom, running through with 2 - 8 gram bodied floats and the other was bleaking up in the water. There were some bream caught and as expected the end pegs dominated - so USA and the Czech Republic had a section winner each because they drew near the end of a section. For most competitors however the match was about deciding when to fish for bleak and when to fish for the roach. After that, good line control and feeding sorted the pecking order out. A quick section by section rundown will give you some idea: Section A A rock hard section won by American Marck Green (a fitting result given the previous weeks news) which saw a number of blanks. Alan Scotthorne was blanking for much of the match but he caught a decent roach to lift him to 14th in section. Didier Guessard did the least well of the French squad and came in 18th with a couple of bleak, and a poor Italian performance - beaten either side - left them with just 20 points. For all the main teams, this proved the lowest scoring section. Section B This section was where Frenchman Diego da Silva thrilled the home crowd - catching a bream of 2.800kg as part of a near 6kg top individual weight. Steve Gardener did well with 7 points thanks mainly to some early and late caught fish. Section C Czech international Jan Heidenreich took the honours with 4.850kg but Bob Nudd struggled for 940gr and 9 points from the better end of the section. Jean Desque got 10 points fishing at the poorer end. Section D Here Will Raison caught a large roach and a bonus perch that helped lift him to 8th in what proved a mainly bleak section. The section was won by Ian Leach of Wales off the end peg with a bonus chub in his 2.200kg bag. Section E Stuart Conroy did well in the hardest part of the section for 11th place. Trabucco came in 4th with over a kilo of small roach. Polish rod Piotr Lorenc took top points with 2.200kg. Tomorrow it looks like all the English squad are out of individual medal contention. The smart money is on Diego but if he draws in D or E section, where no bream showed at all, then its open house! Whatever happens, the teams will need to sort out whether they go for roachor bleak first, it will not the same in each section so there will be a lot of discussion done tonight. To sum it up - hard, but not a lottery. I think this is a technical world champs where the good anglers will come out on top. More on Monday with a full summary after we see how it all pans out, plus loads of pics to mull over. Don't forget the main winners on Sunday at about 6.30 British time.


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Written by Troy residents and Troy business owners, with additional posts by Times Union reporters
Posts filtered on Category
A new home for RPI's president
Rensselaer Polytechnic Institute will build a new residence for President Shirley Ann Jackson, replacing her existing campus home with a larger building. RPI's Board of Trustees on Friday approved the building, which will be funded by personal donations from members of the board. The project was announced to school and employees in campus-wide e-mail sent […]
[Read More]
Apartments for the homeless coming to Little Italy
The state has given Joseph's House, which operates two shelters in the city, $3 million for the construction of an apartment building for the homeless on Fourth Street. The money means Joseph's House can finally begin construction of the three-story building planned for a site near the Flavour Cafe and DeFazio's Pizza. The area is […]
[Read More]
What should the City Hall site become?
The city announced this morning it will hold the first of several public hearings Wednesday on the future of City Hall and the planned redevelopment of the current City Hall site. The meeting is scheduled for 6 to 9 p.m. at the Christ Church United Methodist church at the corner of State Street and Fifth […]
[Read More]
Troy Food Co-Op: Overview
To view a handy one-page overview of the information that was shared at the last Troy Community Food Co-Op meeting, click here. Remember that if you have any questions or would like to purchase a membership, you can contact any one of the Board of Directors.
[Read More]
Troy Co-Op in the home stretch
Last night I attended a meeting for the Troy Community Food Co-Op, an ambitious community-powered retail project that has been in the works for quite a while (at least a few years). Our city is sorely in need of a fully functional, affordable grocery store in walkable distance to downtown. The Co-Op aims to fill […]
[Read More]
Troy is a November cover girl
It isn't too often that Troy makes the cover of a magazine, as it has this month. A lovely shot of the city graces the front of Planning. OK … so the magazine of the American Planning Association isn't exactly Time or People. But it is read by movers and shakers in urban development and […]
[Read More]
Demolish the Proctor's interior? Or restore it?
The City Council last night voted to support a review of a plan that would, if successful, prevent the demolition of Proctor's Theater and reopen the auditorium as a performing arts space. Proctor's, of course, has for decades been a grim and boarded-up site, and a thorn in the side of downtown boosters. The city […]
[Read More]
Dinosaur Bar-B-Que on the agenda
The Dinosaur Bar-B-Que plan is on the agenda for the next meeting of the Troy Planning Board. Here's the item: Conceptual Review of a proposal to occupy a vacant commercial building with a BBQ restaurant and bar. Project location is 377 River Street, a B-4 Zone ID 101.45-1-2. Applicant is Bergmann Associates for Dinosaur BBQ […]
[Read More]
A plan for an entirely new neighborhood
Curious about the road construction happening now along Congress Street? That road and sewer work is paving the way (excuse the pun) for massive amount of development pictured in the master plan above. (The red buildings would be built in the near term by the United Group, while the yellow buildings are future construction.) As […]
[Read More]
A modern look for Troy condos
A posted this on my real estate blog a few days ago, but it has obvious relevance for readers here. The rendering above is the Post Creek condo project, which would be built near the Brunswick line between Route 2 and Poestenkill Creek. The development, which has city approval, would include 47 units. The style […]
[Read More]
Show More


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Child Care Summit: Future Directions
This video was produced in conjunction with the Child Care Summit, sponsored by the Joint Committee on the Status of Women at Harvard and held in January 2011. The summit's goals was to heighten the awareness of child care needs in the work environment, with a particular focus on the Harvard Longwood Campus, and to promote thoughtful discussion by identifying both critical needs and possible solutions. This summit provided an impetus for developing a set of workable recommendations for the futur
Kidney Sales and Moral Arguments, Janet Radcliffe Richards
The arguments used to justify the conclusion that kidney selling should be prohibited are remarkable. What lies at the root of these emotions, and what relevance should they have in practical decision making? When the kidney selling scandal first erupted in the UK, about fifteen years ago, the response was remarkable for its immediacy and unanimity. Politicians who agreed about almost nothing else joined in rushing to make the practice illegal, and professional bodies instantly declared it out o
Yellowstone: Monitoring the Fire Below
This interactive feature story is part of Science Bulletins, an innovative online and exhibition program that offers the public a window into the excitement of scientific discovery. Published in June 2006, this Earth Bulletin looks at the geologic history of Yellowstone National Park. It includes the following components: Three online essays - Yellowstone National Park Is a Volcano, Signs of Restlessness, and Volcanic Witness; An Interview with Bob Smith -- each available in a print-friendly for
3.1.1 (A) Science and certainty
Providing an overview of current issues in UK science education, this unit examines what type of science the curriculum should cover and for what purpose. The unit will introduce you to practical problems in the delivery of an effective science curriculum, and particular questions at all three educational tiers - primary, secondary and tertiary - will be touched on.
セミナー/講演会 のりさんと科学を語ろう!!第2回「北海道の農業ビジネス�
Description not set
Further reading
What is emotion? This unit takes a philosophical approach to this question in an attempt to understand why people respond to events in a certain way. Is there a difference between an emotion and a bodily feeling or is one a consequence of the other?
FACES: Nursing Education major
A Del Mar College Nursing Education major reflects on his experiences to date in the program as well as the scholarships he earned through the DMC Foundation, Inc.
Just Passing Through? -Mediating Scales and Landscapes of Migration in the Dominican Republic.
Emil Rodríguez Garabot MIT- Humphrey Fellow, Dominican Republic 2010-2011.
"The Mirador Sur Park and the 1998 Tsunami False Alarm" Anticipation, mobilization and outrageousness for a new ecological urbanity in Santo Domingo .
Deepak Lamba-Nieves- MIT-lDG, PhD Candidate
"Social Remittances and Development Logics" Social Trans(actions) from Boston to Baní, and from Baní to Boston.
Shaney Peña Gómez- Prof. Landscape Arch. PUCMM in the Dominican Repub
21H.207 The Energy Crisis: Past and Present (MIT)
This course will explore how Americans have confronted energy challenges since the end of World War II. Beginning in the 1970s, Americans worried about the supply of energy. As American production of oil declined, would the US be able to secure enough fuel to sustain their high consumption lifestyles? At the same time, Americans also began to fear the environmental side affects of energy use. Even if the US had enough fossil fuel, would its consumption be detrimental to health and safety? This c
Deconstructed: How Bike Pumps Work
This 2:49 long video shows students how the air pump works, but does not use graphics and simply provides a brief explanation as the air pump is taken apart.
Soorten Frans: Les traits distinctifs du français au Canada
Op het einde van deze les kan je een tekstje geschreven in het Frans van Québec herschrijven in het Frans uit Frankrijk.
Molecular Golgi Traffic Illustrations
The tenth of 14 PowerPoint files containing slides for a topical unit of medical cell biology instruction within the broader categories of Cellular Membranes, Organelles and Molecular Traffic, and Cytoskeleton. Only slides containing illustrations are included. Although text slides are not provided, image slides featuring text are intact. PowerPoint animation of text and images has been removed, but there are several slide sequences that when shown consecutively provide image animation. Illustra
Neil Pappalardo
Description not set
ISS Update - May 2, 2011
The International Space Station video update for May 2, 2011.
Pacific Temperature Anomalies with Graph
This animation shows the El Nino-La Nina Sea Surface Temperature Anomaly from January 1997 through July 1999. A graph inset shows the global average sea surface temperature fluctuation during this time period.
3.4.1 Try some yourself
Scientific calculators are a wonderful invention, but they're only as good as the people who use them. If you often get an unexpected – or ridiculous – result when you press the 'enter' button, this unit is for you. Learn how to do a calculation correctly and get the right answer every time.
Landsat 7 Side-by-side Comparison of a Zoom Down to Washington DC
Side-by-side comparison of 30 meter resolution data on the left with 15 meter resolution data on the right, in a zoom down of the DC area from Landsat 7 data acquired on May 11, 1999
Portland Flyby
A flyby of Portland, from Landsat data
Ik ben de grote broer van 't Kiel Oussama (18) hangt als rapper vooral rond op het podium van Zappa, het jongerencentrum van 't Kiel. Maar op straat speelt hij grote broer voor heel veel buren. "Iedereen krijgt van mij een eerlijke kans." Werkblad bij een artikel uit Maks …
6.2 Devices in the home
Are you a technophobe? Bluetooth, Ethernet WiFi – are they terms that mean nothing to you? This unit will gently guide you to an understanding of how devices 'talk' to each other and what technologies and processes are involved. You will also look at wired and wireless communication technologies, introducing you to some of the key methods involved.


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America's Leading Gay News Source
Uganda anti-gay law challenged in court
SMYAL executive director to step down
Catania to run for mayor
Bipartisan organizations will shape our movement
Brewer's 'turn away the gay' veto not universally popular at CPAC
'Promoter bill' wrong approach with negative results
All Va. Dem leaders must back marriage equality
Springing into action
With any luck, this past week brought the last frost of the season and many of the outdoor LGBT sports teams are in full swing.
The D.C. Front Runners continue to host their Tuesday and Thursday evening runs along with their Saturday and Sunday morning runs. The group meets at 23rd and P streets during the week and at Rock Creek Park on the weekends. The runners also host walks at the same locations on Tuesday evenings and Saturday mornings.
Recently the Front Runners launched a 10-week series of track workouts which will run through the middle of May. The sessions are on Wednesday nights from 7 to 8 p.m. and will rotate between McKinley High School and Banneker High School. The rotation can be found atdcfrontrunners.org.
Congratulations to the Washington Renegades RFC members for kicking off their spring season by winning the Gray Ghost Cup tournament in Bel Air, Md., on March 10. Their Blues squad took down North Bay, Lockport, Pax River and the Washington Rugby Club to win the tournament.
This weekend the Blues squad will travel to Charlottesville, Va., to take on Virginia RFC, while the Reds squad will be at home playing the Washington Poltroons. The Renegades schedule can be found at dcrugby.com.
Among the many opportunities offered by the D.C. Strokes Rowing Club is the Learn to Row Program. This season, to accommodate busy schedules, they are holding four different sessions on weekdays and weekends.
The sessions begin at the end of April, assume no previous rowing experience and teach the basics from square one. Rowers who complete the program are invited to join the team as part of their Novice Program. More information is at dcstrokes.org.
The recreational biking series has begun for the Adventuring outdoors group and on Saturday, they will host the Washington & Old Dominion Rail-To-Trail. This will be an easy, paved and mostly flat trail ride to help riders get in shape for more challenging events to come. The route will run from Falls Church to Herndon and back and will be a 29-mile ride. Riders will meet at 10:30 a.m. at the East Falls Church Metro Station in the Kiss & Ride Lot. Bring helmet, fluids and $2. The group will stop for a quick lunch at a Herndon restaurant or you can pack a lunch. Contact Mike at email@example.com for more information.
Adventuring has also rescheduled the Scott's Run Preserve Hike on Sunday. The hike will be in the range of 2.2 to 3 miles. The hikers will go past the waterfall on Scotts Run and follow along the Potomac River to the Palisades of the Potomac. The group will also stop by the Burling House ruins as they cross through the area. Carpooling to the preserve will depart at 9:30 a.m. from the Rossyln Metro Station. Bring fluids, bug spray and a packed lunch plus $2 trip fee and $3 for non-drivers. You can RSVP at meeting.com/Adventuring-Gay-
The Capital Tennis Association coordinates league play throughout the year at both tennis clubs and public courts. Registration for the summer leagues for both singles and doubles will begin in April and the league runs from May to September. There is also the opportunity to sign up for sub spots on the league. More information on the tennis players is atcapital-tennis.org.
The first tee off of the season for the Lambda Links Golf Club will be Sunday. The golfers can be found on the greens every weekend through October 28. Join the group's mailing list at lambdalinks.org for information on its tee-off locations.
The District of Columbia Aquatics Club will be hosting the 21st annual Swim for Life on July 14. The event is a fundraiser for HIV/AIDS nonprofits as well as local watershed organizations. Swimmers will compete in 1-, 2-, 3-, 4- or 5-mile races beginning and ending at Rolph's Wharf on the Chester River. This is also a great opportunity for anyone training for a triathlon. Details on the event are at swimdcac.org.
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Bio-degradable Foam Air Filter
Refill of the non-alcohol-based, dirt-grabbing, water resistant, super-tacky filter oil for foam air filters. This Air Filter Oil can only be washed out with the Biodegradable Foam Air Filter Cleaner and water. It won't wash out with gasoline, solvents or water alone.Page / 1 /
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Diablo III auction house closing in March 2014 | |
Posted: 17.09.2013 23:42 by | Comments: 10 |
Blizzard has announced that it's rectifying what many fans of the series considered a mistake: the Diablo III auction houses, both real money and in-game gold, are being removed on the 18th March, 2014. According to the Battle.net blog: "When we initially designed and implemented the auction houses, the driving goal was to provide a convenient and secure system for trades. But as we've mentioned on different occasions, it became increasingly clear that despite the benefits of the AH system and the fact that many players around the world use it, it ultimately undermines Diablo's core game play: kill monsters to get cool loot. With that in mind, we want to let everyone know that we've decided to remove the gold and real-money auction house system from Diablo III. We feel that this move along with the Loot 2.0 system being developed concurrently with Reaper of Souls™ will result in a much more rewarding game experience for our players. We're working out the details of how the auction house system will be shut down, but we wanted to share the news as soon as we made the decision in order to give everyone as much advance notice as possible. Please note that the shutdown will occur on March 18, 2014. We will keep everyone informed as we work through this process." The developer also released a video making the announcement. What's next - enabling offline play for the PC version to match the console versions? Perish the thought. |
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Mum is banned from school playground after brawling with another parent
Lucy Weir has not been allowed into the grounds of Yenton Primary School, in Erdington, since fight five months ago
TRAVEL: Just when you thought it was safe to get back on the motorway we have a cone on the loose.
More »NEWS: It was the treasure find of the century and now the Staffordshire Hoard has been displayed in one room at one time.
NEWS: We're not sure what 15-year-old Harry Kirton did during his audition but it must have been blinding.
FRONT PAGE: And (eventually) here's today's Birmingham Mail Front page.
TRAVEL: Elsewhere on the roads this morning things are relatively normal.
More »NEWS: Speaking of the M6 - how many of you were caught up in yesterday's chaos?
TRAVEL: First up and we have - hard to believe I know - a problem on the M6.
More »UPDATE: It seems gremlins crept into the machine last night, been battling technical difficulties all morning.
More »WELCOME: I was assured, assured I tell thee, that today would be sunny. I'm sure even though we're off to a very gloomy start things will pick up shortly.
More »


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Your favorite Apple, iPhone, iPad, iOS, Jailbreak, and Cydia site.
Thread: How does iPhone's automatic backlight adjustment feature work?
is a discussion within theGeneral iPhone Chat
forums, a part of theiPhone Modding
section;I'm a bit puzzled by it. I have my brightness at a mere 20% or so because it's totally sufficient and still looks very nice, and I have automatic backlight
07-27-2007, 09:16 AM #1How does iPhone's automatic backlight adjustment feature work?
I'm a bit puzzled by it. I have my brightness at a mere 20% or so because it's totally sufficient and still looks very nice, and I have automatic backlight adjustment turned on. If I jack the brightness up to 80% or 100%, still with automatic backlight turned on, it seems to just stay at that percentage rather than automatically lowering the brightness. What's the deal with this feature? How does it work?
I never notice it making the screen dimmer or brighter based on the surrounding lighting conditions.
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i keep mine really dim and notice if under my shirt the screen is dark at first, what i want to know is exactly where the ambient light sensor is located on the iphone
gotta be by the earpiece, thats why the screen shuts off when you put your ear next to it in a call........
It's easy to test as well. Just put your thumb over the ear piece, roughly, and the screen will dim just like when you put it up to your face.
I just don't quite understand the logic. In fact, when the automatic backlight feature is enabled, the bar for brightness adjustment should be unavailable to the user, because, well, it's automatically adjusted! That's the whole point of the feature. Instead, iPhone, for some strange reason, still lets you use the slider even with automatic backlight turned on. I don't get it.. hence this thread and the question about how it works.


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US Open 2012: 5 Byron Nelson Standouts Ready to Shock at the Olympic Club
By David Kindervater ,
Jason Dufner
With the 2012 US Open just a little more than three weeks away, it's time to start getting serious about picking the contenders.
The Olympic Club in San Francisco will play host to the 112th playing of golf's toughest test, and the field is naturally an impressive one.
Sure, there's the world's top-ranked player and defending champion Rory McIlroy. His play at a couple events this year has been suspect—especially at the Masters Tournament last month where he finished T40—but for the most part, he's been playing very well.
Of course, there's Tiger Woods. I picked Tiger to win his 15th major championship this year, but your guess is as good as mine when it comes to which Tiger Woods we'll see at the US Open. The Tiger of old reappeared in winning the Arnold Palmer Invitational by five strokes in March, but like McIlroy, he finished T40 at the Masters and has been inconsistent this season.
I'm also guessing players like Phil Mickelson, Luke Donald, Lee Westwood, Bubba Watson and Matt Kuchar will have something to say about the outcome of this championship.
But what about those dark horse candidates who won't bring the same flair of the aforementioned golfers, but who could play surprisingly well?
The PGA Tour made a stop at the HP Byron Nelson Championship this past week and several players notched standout performances that got my attention heading into this year's second major.
Here are five Byron Nelson standouts who just might be ready to shock the world at the Olympic Club.
Jason Dufner is learning how to win.
In claiming the Byron Nelson Championship, Dufner posted his second victory of the 2012 season. In fact, it was his second win in three starts after beginning his career without a victory in 163 events.
Is it premature to get too excited about Jason Dufner's game? I don't think so.
Dufner is taking his PGA Tour best "before the cut" scoring average and playing well when it matters the most—on Sunday.
He's also fourth in total driving and 13th in greens in regulation on the PGA Tour this year. That kind of consistency is a formula for success anywhere he plays. He still needs to improve his performance with the flat stick, but the results are beginning to speak for themselves.
Dufner, the playoff runner-up at last year's PGA Championship and current FedExCup points leader, moved to the No. 14 spot in the Official World Golf Ranking and solidified himself as a serious threat at the Olympic Club.
There are plenty of reasons to believe Robert Garrigus will be successful at the 2012 US Open.
He hits the ball on average almost 310 yards from the tee box. Only Masters champion Bubba Watson bombs it farther. Given the Olympic Club's ample length, specifically on the treacherous first six holes, Garrigus will need that distance.
Length off the tee. Check.
Garrigus is sixth on the PGA Tour in greens in regulation. The Olympic Club has small greens and requires precise iron shots for success.
Accurate approach shots. Check.
Of course, as with any major championship—or any golf tournament for that matter—it comes down to putting, and Garrigus is not getting the job done. He's a dismal 186th in total putting.
Garrigus has managed three Top 10 finishes in 2012, and his recent T9 at the Byron Nelson was highlighted by a closing round of 66. If he can pull all the elements of his game together at the Olympic Club, he could find his name on the weekend leader board.
No one can argue that Jason Day's best hasn't been good enough in 2012.
Day is not playing up to his high standards these days. But his recent Top 10 finishes—at the Byron Nelson and Wells Fargo in the past month—are reasons for optimism.
I'm looking at his track record. Day has proven he can play well at the majors. He finished in second place at last year's Masters Tournament as well as at the US Open. And he had another Top 10 at the 2010 PGA Championship.
So, I'm giving him a fighting chance to pull his game together in time for a tough test at the Olympic Club.
Day, who's looking more and more like Jesus Christ these days, has what it takes to win on the PGA Tour. At just 24-years-old, he has two victories, and he has managed to maintain a Top 20 World Golf Ranking. Along with his successful major championship experience, Day is certainly someone to keep an eye on.
Vijay Singh put himself into a position to win his 35th PGA Tour event at the Byron Nelson Championship. But a final round 71—complete with three straight bogeys to begin his round—dropped him into a disappointing T9 finish.
With so much talk surrounding the young talent on the PGA Tour these days—and rightfully so—it's easy to forget about the veterans who can still get hot and play with the best of them.
Singh is one of those players.
The 49-year-old "Big Fijian" has done most of his damage after the age of 40. In fact, 22 of his 34 PGA Tour wins occurred during that time frame. Granted, he hasn't won since 2008, but few players can match his work ethic and commitment to excellence.
And that goes a long way in terms of longevity in this business.
I'll throw patience into the mix as well. It takes a ton of it to win at the US Open, and that's another quality Singh will bring to the table at the Olympic Club.
Singh has three major championships to his credit plus a slew of US Open Top 10s. Yes, a US Open victory in 2012 would be shocking. But I'd be crazy to count him out.
Like Vijay Singh, Padraig Harrington is a 40-something with three major championships to his credit.
And after an impressive T15 finish at the Byron Nelson Championship, Harrington is beginning to show the consistency he will need to perform well at the Olympic Club.
The knock on Harrington in 2012 is that his rounds have been all over the place. He fired an opening round 61 at the Transitions Championship only to follow with three rounds in the 70s to finish well back of the leaders at T44.
Harrington does have two Top 10s in 2012, including a T8 at the Masters. He almost always gets a good round or two in, but his wide-ranging scores are killing his chances for success.
At the Byron Nelson, he had three rounds in the 60s for the first time this year. I'm not saying he'll need four sub-70 scores to make his presence felt at the US Open. That might be impossible for any player. But he will need to be more consistent if he's going to have a chance.


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Also in Vegas to hear Lionel Richie, Faith rocks a silky red jumpsuit with a statement necklace, J/Hadley earrings and rings, and basic black Barbara Bui sandals.


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Bullet Time Bill
by Doodle Dojo
Stretched Canvas
Fine art print on bright white, fine poly-cotton blend, matte canvas using latest generation Epson archival inks. Individually trimmed and hand stretched museum wrap over 1-1/2" deep wood stretcher bars. Includes wall hanging hardware.
Do you believe that my being stronger or faster has anything to do with my muscles in this place? Do you think those are mushrooms you're eating now?
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Palmetto Ridge gets revenge against Gulf Coast
Palmetto Ridge holds on for 33-27.
Published Sept. 10, 2011
The Palmetto Ridge Bears held on for a 33-27 win in front of their jam-packed stadium Friday against Gulf Coast High School. Video courtesy of NBC-2
Story | Date Posted |
LIVE PREP FOOTBALL SCORING: Gulf Coast at Palmetto Ridge | Sept. 9, 2011 |
PrepZone: Saturday football notebook | Sept. 10, 2011 |
Prep football: Palmetto Ridge gets a little revenge against Gulf Coast | Sept. 9, 2011 |
LIVE PREP FOOTBALL BLOG: Chat, scores, photos and more from Week 2 | Sept. 9, 2011 |
Video courtesy of NBC-2
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40th birthday tiara
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My dear friend Annie gave me a gorgeous bouquet of local Californian flowers and a non-locally-source tiara for my recent milestone. I wear the tiara around the office from time to time when I need to feel empowered.
(That pretty princess in the background is my niece Audrey. She already has several tiaras of her own.)
Photo Credit:
Abraham Mertens
The triumph of intellect and romance over brute force and cynicism."
—Craig Ferguson, describing Doctor Who
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