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Publications (15)107.74 Total impact
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ABSTRACT: Rfv3 is a host resistance gene that operates through an unknown mechanism to control the development of the virus-neutralizing antibody response required for recovery from infection with Friend retrovirus. The Rfv3 gene was previously mapped to an approximately 20-centimorgan (cM) region of chromosome 15. More refined mapping was not possible, due to a lack of microsatellite markers and leakiness in the Rfv3 phenotype, which prevented definitive phenotyping of individual recombinant mice. In the present study, we overcame these difficulties by taking advantage of seven new microsatellite markers in the Rfv3 region and by using progeny tests to accurately determine the Rfv3 phenotype of recombinant mice. Detailed linkage analysis of relevant crossovers narrowed the location of Rfv3 to a 0.83-cM region. Mapping of closely linked genes in an interspecific backcross panel allowed us to exclude two previous candidate genes, Ly6 and Wnt7b. These studies also showed for the first time that the Hsf1 gene maps to the Rfv3-linked cluster of genes including Il2rb, Il3rb, and Pdgfb. This localization of Rfv3 to a region of less than 1 cM now makes it feasible to attempt the cloning of Rfv3 by physical methods.Journal of Virology 10/1999; 73(9):7848-52. · 5.08 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Many human viruses not only cause acute diseases but also establish persistent infections. Such persistent viruses can cause chronic diseases or can reactivate to cause acute diseases in AIDS patients or patients receiving immunosuppressive therapies. While the prevention of persistent infections is an important consideration in the design of modern vaccines, surprisingly little is known about this aspect of protection. In the current study, we tested the feasibility of vaccine prevention of retroviral persistence by using a Friend virus model that we recently developed. In this model, persistent virus can be detected at very low levels by immunosuppressing the host to reactivate virus or by transferring persistently infected spleen cells into highly susceptible mice. Two vaccines were analyzed, a recombinant vaccinia virus vector expressing Friend virus envelope protein and a live attenuated Friend virus. Both vaccines reduced pathogenic virus loads to levels undetectable by infectious center assays. However, only the live, attenuated vaccine prevented immunosuppression-induced reactivation of persistent virus. Thus, even very low levels of persistent Friend virus posed a significant threat during immunosuppression. Our results demonstrate that vaccine protection against establishment of retroviral persistence is attainable.Journal of Virology 06/1999; 73(5):3753-7. · 5.08 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Infection by live attenuated retroviruses provides excellent protection from challenge with pathogenic viruses in several animal models, but little is known about which immune effectors are necessary for protection. We examined this using adoptive transfer experiments in the Friend virus mouse model. Transfers of immune spleen cells into naive mice conferred complete protection, and transfers of purified lymphocyte subsets demonstrated that this effect required complex immune responses involving CD4+ and CD8+ T cells and also B cells. In addition, passive immunization experiments demonstrated that antibodies alone reduced virus loads but did not prevent infection. These findings may have implications for retroviral vaccine design in general.Nature Medicine 03/1999; 5(2):189-93. · 22.86 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Recovery from infection with the Friend murine leukemia retrovirus complex (FV) requires T-helper cells and cytotoxic T cells as well as neutralizing antibodies. Several host genes, including genes of the major histocompatibility complex (H-2) and an H-2-unlinked gene, Rfv-3, influence these FV-specific immune responses. (B10.A x A/Wy)F1 mice, which have the H-2(a/a) Rfv-3(r/s) genotype, fail to mount a detectable FV-specific T-cell proliferative response but nevertheless produce FV-specific neutralizing immunoglobulin M (IgM) antibodies and can eliminate FV viremia. Thus, this IgM response, primarily influenced by the Rfv-3 gene, may be T-cell independent. To test this idea, mice were depleted of either CD4(+) or CD8(+) T-cell populations in vivo and were monitored for the effect on the neutralizing antibody response following FV infection. Surprisingly, mice in which CD4(+) cells were depleted showed undetectable FV-neutralizing antibody responses and high viremia levels compared to nondepleted or CD8-depleted animals. In addition to knocking out the FV antibody response, CD4(+) T-cell depletion reduced survival time significantly, further indicating the importance of CD4(+) T cells. These studies revealed the first evidence for a functional T-cell response following FV infection in these low-recovery mice and showed that CD4(+) T-helper cells are required for the Rfv-3-controlled FV antibody response.Journal of Virology 12/1998; 72(11):9400-3. · 5.08 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Live-attenuated retroviruses have been shown to be effective retroviral vaccines, but currently little is known regarding the mechanisms of protection. In the present studies, we used Friend virus as a model to analyze characteristics of a live-attenuated vaccine in protection against virus-induced disease. Highly susceptible mice were immunized with nonpathogenic Friend murine leukemia helper virus (F-MuLV), which replicates poorly in adult mice. Further attenuation of the vaccine virus was achieved by crossing the Fv-1 genetic resistance barrier. The minimum dose of vaccine virus required to protect 100% of the mice against challenge with pathogenic Friend virus complex was determined to be 10(3) focus-forming units of attenuated virus. Live vaccine virus was necessary for induction of immunity, since inactivated F-MuLV did not induce protection. To determine whether immune cells mediated protection, spleen cells from vaccinated donor mice were adoptively transferred into syngeneic recipients. The results indicated that immune mechanisms rather than viral interference mediated protection.Journal of Virology 09/1998; 72(8):6554-8. · 5.08 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Reactivations of persistent viral infections pose a significant medical problem in immunocompromised cancer, transplant, and AIDS patients, yet little is known about how persistent viral infections are immunologically controlled. Here we describe a mouse model for investigating the role of the immune response in controlling a persistent retroviral infection. We demonstrate that, following recovery from acute Friend virus infection, a small number of B cells evade immunological destruction and harbor persistent virus. In vivo depletions of T-cell subsets in persistently infected mice revealed a critical role for CD4(+) T cells in controlling virus replication, spread to the erythroid lineage, and induction of erythroleukemia. The CD4(+) T-cell effect was independent of CD8(+) T cells and in some cases was also independent of virus-neutralizing antibody responses. Thus, the CD4(+) T cells may have had a direct antiviral effect. These results may have relevance for human immunodeficiency virus (HIV) infections where loss of CD4(+) T cells is associated with an increase in HIV replication, reactivation of persistent viruses, and a high incidence of virus-associated cancers.Journal of Virology 09/1998; 72(8):6559-64. · 5.08 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Several immunological epitopes are known to be located within the Friend murine leukemia virus (F-MuLV) envelope protein, but their relative contributions to protection from Friend virus-induced disease are not known. To determine how expression of various immunological determinants affected protection, mice were immunized with recombinant vaccinia viruses expressing different portions of the F-MuLV envelope protein, and they were then challenged with a lethal dose of Friend virus complex. The disease parameters that were followed in the mice were early viremia, early splenomegaly, and late splenomegaly. Both the N-terminal and C-terminal portions of the F-MuLV gp70 were found to protect against late splenomegaly, the primary clinical sign associated with virus-induced erythroleukemia. However, neither region alone protected against early splenomegaly and early viremia, indicating poor immunological control over early virus replication and spread through the spleen and blood. In contrast, mice immunized with a vaccine expressing the entire F-MuLV envelope protein were protected against all three disease parameters. The results indicated that expression of multiple immunological determinants including both T-helper and B cell epitopes was necessary for full protection.Virology 09/1998; 248(1):66-73. · 3.37 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: A retroviral vector (pSFF) derived from murine Friend spleen focus forming virus was used to transduce murine hematopoietic stem cells and express a cell surface marker protein, mutated murine prion protein, in vitro and in vivo after transplantation. To enhance retroviral vector integration in bone marrow cells, mice were treated with 5-fluorouracil (5-FU) to increase stem cell mitotic activity, which peaked on day 8 post-5-FU. The infectivity titer of the vector, pSFF-mPrP-3F4, was determined by a novel assay in which antigen-positive foci of infected cells were detected after replication and spread of the vector in cultures of mixed packaging cell lines. Infection of Sca-1+/Lineageneg-low cells with pSFF-mPrP-3F4 resulted in marker protein expression in 40% of the progeny cells after 7 days of culture. Transplantation of marrow cells or sorted Sca-1+/Lineageneg-low cells transduced with vector resulted in 3F4-positive mPrP expression in 11% to 37% of donor-derived peripheral blood leukocytes at 2 weeks. Though the percentage of 3F4-positive blood cells gradually declined, at 28 weeks 23% of recipient mice still maintained expression of the marker gene. Expression was observed in lymphoid, myeloid, and erythroid lineages and was detected in Sca-1+/Lineageneg-low marrow cells. The multilineage, high-frequency expression observed suggests that pSFF may be useful in gene therapy directed at hematopoietic stem cells and their differentiated progeny.Blood 02/1996; 87(2):509-17. · 9.06 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Friend murine leukemia virus is a retrovirus complex that induces rapid erythroleukemia and immunosuppression in susceptible strains of adult mice. Using this model, we directly examined the T-cell subsets required for a protective retrovirus vaccine. Paradoxically, recovery in mice immunized with a chimeric envelope containing only T-helper (TH) and B-cell epitopes was dependent on CD8+ T cells as well as CD4+ T cells despite the fact that the vaccine contained no CD8+ cytolytic T-lymphocyte (CTL) epitopes. However, the requirement for CD8+ T cells was overcome by inclusion of additional TH and B-cell epitopes in the immunizing protein. These additional epitopes primed for more rapid production of virus-neutralizing antibody which appeared to limit virus spread sufficiently to protect even in the absence of CD8+ T cells. Inclusion of an immunodominant CTL epitope in the vaccine was not sufficient to overcome dependence on CD4+ T cells. These data suggest that TH priming is more critical for retrovirus immunity than CTL priming.Journal of Virology 01/1996; 70(1):368-72. · 5.08 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Administration of virus-specific antibodies is known to be an effective early treatment for some viral infections. Such immunotherapy probably acts by antibody-mediated neutralization of viral infectivity and is often thought to function independently of T-cell-mediated immune responses. In the present experiments, we studied passive antibody therapy using Friend murine leukemia virus complex as a model for an immunosuppressive retroviral disease in adult mice. The results showed that antibody therapy could induce recovery from a well-established retroviral infection. However, the success of therapy was dependent on the presence of both CD4+ and CD8+ T lymphocytes. Thus, cell-mediated responses were required for recovery from infection even in the presence of therapeutic levels of antibody. The major histocompatibility type of the mice was also an important factor determining the relative success of antibody therapy in this system, but it was less critical for low-dose than for high-dose infections. Our results imply that limited T-cell responsiveness as dictated by major histocompatibility genes and/or stage of disease may have contributed to previous immunotherapy failures in AIDS patients. Possible strategies to improve the efficacy of future therapies are discussed.Proceedings of the National Academy of Sciences 12/1995; 92(23):10492-5. · 9.74 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Hematopoietic stem cells were isolated from normal adult mouse bone marrow based on surface antigen expression (Thy-1.1(low)Lin(neg)Ly-6A/E+) and further selected for low retention of rhodamine 123. This population of cells (Rh-123low) could mediate radioprotection and long-term (greater than 12 months) repopulation after transplantation of as few as 25 cells. Transfer of five genetically marked Rh-123low cells in the presence of 10(5) normal bone marrow cells resulted in reconstitution of peripheral blood by greater than 10% donor cells in 64% (30 of 47) of recipient mice. Of 46 animals surviving after 24 weeks, 10 had over 50% donor-derived cells in peripheral blood. Two general patterns of long-term reconstitution were observed: one in which many donor-derived cells were observed 5 to 6 weeks after reconstitution and another in which donor-derived cells were rare initially but expanded with time. This result suggests that two classes of long-term repopulating hematopoietic stem cells exist, differing in their ability to function early in the course of transplantation. Alternatively, distinct anatomic sites of engraftment may dictate these two outcomes from a single type of cell. As an approach to measure the extent of self-renewal by the injected cells, recipients of five or 200 stem cells were killed 8 to 13 months after the transplants, and Thy-1.1(low)Lin(neg)Ly-6A/E+ progeny of the original injected cells were isolated for a second transplant. While a numerical expansion of cells expressing the cell surface phenotype of stem cells was observed, along with activity in the colony-forming unit-spleen assay, the expanded cells were vastly inferior in radioprotection and long-term reconstitution assays when compared with cells freshly isolated from normal animals. This result demonstrates that in stem cell expansion experiments, cell surface antigen expression is not an appropriate indicator of stem cell function.Blood 03/1995; 85(4):1006-16. · 9.06 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Mice homozygous for the b allele of the MHC gene, H-2D, have a high incidence of recovery from Friend virus infections, while mice heterozygous for the b allele at H-2D have a very low incidence of recovery. Previous experiments indicated that the low recovery rates associated with heterozygosity at H-2D might be related to a gene dosage effect requiring the expression of two H-2Db alleles for high recovery. We investigated the effects of reduced H-2Db expression on recovery from Friend disease by using H-2b homozygous mice carrying a single beta 2-microglobulin gene disruption. These mice had reductions in cell surface H-2Db expression comparable to those of H-2Da/b heterozygotes. Numerous cell types with various levels of H-2Db expression were examined, and in each case, the expression levels in the beta 2-microglobulin mutants closely reflected those observed in the H-2Da/b heterozygotes. We found, however, that reduced expression did not affect recovery from Friend disease, indicating that heterozygous levels of H-2Db expression are sufficient for the high-recovery phenotype previously associated only with H-2Db homozygotes.Journal of Virology 05/1994; 68(4):2059-64. · 5.08 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: The cell surface molecule Ly-6A/E provides a convenient marker for primitive stem cells in the hematopoietic tissues of both fetal and adult mice. However, previous studies have shown that Ly-6A/E expression by lymphocytes is variable depending on the haplotype of the Ly-6 locus. Therefore, strain-specific variation in Ly-6A/E expression by bone marrow (BM) cells was investigated. The results show that Ly-6a mice have, on average, 50% of the number of BM cells expressing Ly-6A/E relative to that for Ly-6b mice. Furthermore, among the 5% of BM cells that do not express antigens characteristic of mature T, B, myeloid, or erythroid lineages, which include the primitive hematopoietic stem cell compartment, Ly-6a mice have, on average, more than fivefold fewer Ly-6A/E+ cells relative to that for Ly-6b mice. Isolation of Ly-6A/E- and Ly-6A/E+ cells from mice of both haplotypes showed that, whereas 99% of the marrow repopulating activity (MRA) of C57BL/Ka (Ly-6b) mice could be recovered in the Ly-6A/E+ fraction, only about 25% of the MRA of BALB/c (Ly-6a) was recoverable in the same population. On a per-cell basis, the Ly-6A/E+ cells that were isolated from BALB/c mice were essentially equivalent in MRA to those isolated from C57BL/Ka mice. Thus, whereas a large percentage of the hematopoietic stem cells of Ly-6a mice do not express the Ly-6A/E molecule, the antigen may be used to isolate a subset of stem cells from these mice. These results show that hematopoietic stem cell phenotype can vary between mouse strains and imply that caution should be exercised in the identification of human stem cell antigens such as CD34, because a similar variability may occur between individual humans. To further explore the influence of Ly-6 haplotype on Ly-6A/E expression by specific cell subsets, lymph-node lymphocytes from a panel of mouse strains were analyzed by multiparameter flow cytometry for correlated expression of Ly-6A/E, CD4, and CD8. All Ly-6a strains examined had less than 20% Ly-6A/E+ cells, and those cells were predominantly CD8+ T lymphocytes. In contrast, the Ly-6b strains had greater than 30% Ly-6A/E+ cells, and those cells included CD4+, CD8+, and B lymphocytes.Blood 01/1994; 82(11):3327-32. · 9.06 Impact Factor - [show abstract] [hide abstract]
ABSTRACT: Mouse hematopoietic stem cells can be identified and enriched from populations of normal bone marrow cells by immunofluorescent labeling of cell surface molecules followed by flow cytometric separation. We show here that the majority of hematopoietic stem cell activity, as defined by long-term competitive repopulation of irradiated animals and by a secondary transplant assay for spleen colony-forming units (CFU-S), could be localized in Ly-6b haplotype mice to a fraction of bone marrow cells that expresses the Ly-6A/E (Sca-1) molecule. Further, an analysis of hematopoietic stem cell activity in bone marrow of mouse strains expressing the Thy-1.1 allele indicated that the vast majority of activity was included in the Thy-1low population. In contrast, hematopoietic stem cell activity found in the bone marrow of Thy-1.2 genotype mouse strains was recovered in both the Thy-1neg and the Thy-1low populations. However, similar to Thy-1.1 strains, most activity was localized to the Ly-6A/E+ population of cells. The difference in Thy-1 phenotype of hematopoietic stem cell activity apparent between Thy-1.1- and Thy-1.2-expressing mouse strains was not caused by differences in the staining intensity of monoclonal antibodies (MoAbs) specific for the Thy-1 alleles. Furthermore, an antiframework MoAb that stains both alleles of Thy-1 separated hematopoietic stem cell activity from mice expressing the two alleles in the same manner as did allele-specific MoAb. The results of this study show that Thy-1 expression is not an invariant characteristic of mouse hematopoietic stem cells, and that mice expressing the Thy-1.1 allele are unique in that hematopoietic stem cell activity is found exclusively in the Thy-1low population.Blood 11/1992; 80(8):1957-64. · 9.06 Impact Factor -
Article: Recovery fromFriend Disease inMicewithReducedMajor Histocompatibility ComplexClass IExpression
Publication Stats
609 | Citations | |
107.74 | Total Impact Points | |
Top Journals
- Journal of Virology (7)
- Blood (4)
- Proceedings of the National Academy of Scienc... (1)
- Virology (1)
- Nature Medicine (1)
University of Kentucky
- Department of Biochemistry
Lexington, Kentucky, United States
National Institute of Allergy and Infectious Diseases
Maryland, United States


text:
In Bourhill v. Nextel of New York, Inc., 2013 WL 1680140 (D.N.J. Apr. 17, 2013), an employee with a back condition was granted several consecutive leaves of absences (spanning eight months of leave), followed by an open-ended...more
9/24/2013 - Disability Indefiniteness Reasonable Accommodation Unpaid Leave
In Rowan v. Hartford Plaza Ltd., 2013 WL 1350095 (N.J. App. Div. Apr. 5, 2013) (unpub.), the New Jersey Appellate Division held—in an unpublished opinion—that individual supervisors are subject to "aiding and abetting"...more
9/23/2013 - Aiding and Abetting Discrimination Statutory Interpretation Supervisors
In Mercado v. Donahoe, No. 11-2972, 2012 U.S. App. LEXIS 13226, (3rd Cir. June 26, 2012), the plaintiff, a probationary part-time employee, sued his employer alleging that he had been discriminated against on the basis of his...more
8/16/2012 - Discrimination Probationary Period Racial Discrimination Sex Discrimination Substantially Similar
In Harriel v. Wal-Mart Stores, Inc., No. 11-2510 (MLC), 2012 U.S. Dist. LEXIS 97527, (D.N.J. July 13, 2012), the District Court of New Jersey denied the plaintiff's motion for conditional certification as an FLSA collective...more
8/16/2012 - Class Action Class Certification FLSA Misclassification Non-Exempt Employees Wal-Mart
In Kiernan v. AAA Mechanical, Inc., No. 10-4421 (MLC), 2012 U.S. Dist. LEXIS 90655, (D.N.J. June 29, 2012), the plaintiff sued her employer for overtime compensation under the New Jersey Wage and Hour Law shortly after the...more
8/16/2012 - Unpaid Overtime Wage and Hour Wages
In Warwas v. City of Plainfield, No. 11-1736, 2012 U.S. App. LEXIS 15324, (3rd Cir. July 25, 2012), an employee terminated while on FMLA leave sued for interference with her FMLA rights. The employer asserted it terminated...more
8/16/2012 - FMLA FMLA Abuse Hiring & Firing Termination
In Fouche v. New Jersey Transit, No. 11-3031, 2012 U.S. App. LEXIS 14524, (3rd Cir. July 16, 2012), a bus driver sued his employer under Title VII and the New Jersey Law Against Discrimination for refusing to accommodate his...more
8/16/2012 - Discrimination Reasonable Accommodation Religious Discrimination Title VII Undue Hardship
Reasonable Accommodation
Aiding and Abetting
Class Action
Class Certification
FMLA Abuse
Hiring & Firing
Non-Exempt Employees
Probationary Period
Racial Discrimination
Religious Discrimination
Sex Discrimination
Statutory Interpretation
Substantially Similar

subset: commoncrawl


text:
Darth Vader = The Godfather
Do not trust Boba Fett
Movie Super Villains Get Old Too
May the Force of #Typography be with you #starwars #vader
Darth Vader aussi avait un chien =)
Starwars Identities - The Exhibition - Awesome poster
Vader's mood
Not the best movie ever, but surely the best poster movie ever!
What is the favorite book of Darth vader?
shirtoid: I Feel So Pretty available at RedBubble -Don Vlader!!!
I Feel So Pretty available at RedBubble
-Don Vlader!!!
Star Wars Typography: Darth Vader Created With His Quotes


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Imran Khan urges Taliban to join peace talks
Submitted by Pankaj Mathur on Wed, 12/18/2013 - 21:47.Islamabad, Dec 18 : Pakistan's cricketer-turned-politician Imran Khan Wednesday appealed to the Pakistani Taliban to participate in the peace talks with the government, a media report said.
Khan, who is the chairman of the Pakistan Tehreek-e-Insaf (PTI), said there was a need for peace in the country and urged the Taliban to start the talks, Geo News reported.
He said restoration of peace in Pakistan was not possible until US drone attacks stopped.
The Pakistani Taliban has refused to talk to the government after a US drone attack killed their chief, Hakimullah Mehsud, in North Waziristan tribal region Nov 1.
Imran awarded for standing up against dog abuse
Submitted by Gurdeep Singh Tiwana on Fri, 11/22/2013 - 20:24.Mumbai, Nov 22 : Actor Imran Khan has been awarded by animal rights organisation People for the Ethical Treatment of Animals (PETA) India for stopping a trainer from hitting a canine on his film set.
Imran was reportedly shooting for "Gori Tere Pyaar Mein" when he saw the dog trainer smack a dog. He immediately walked up to the trainer and pushed him in order to stop the abuse.
PETA has now sent Imran a Hero to Animals Award and a basket full of dog-shaped vegan gourmet chocolates prepared by Pune's Ambrosial Chockies as a mark of appreciation for his deed.
Imran best in 'Gori Tere Pyaar Mein': Kareena
Submitted by Supreet Sharma on Wed, 11/20/2013 - 19:31.Mumbai, Nov 20 : Actress Kareena Kapoor has praised Imran Khan's performance in "Gori Tere Pyaar Mein", saying he has given his best in the romantic drama coming out Friday.
"Imran is a lot more fun," said Kareena who has teamed up with him for the second time after "Ek Main Aur Ekk Tu".
"In this film ('Gori Tere Pyaar Mein'), he has definitely opened up a lot more as an actor. In the film, Imran has given his best performance. He has performed like a hero," she added.
'Bhavesh Joshi' no superhero film: Imran Khan
Submitted by Supreet Sharma on Thu, 11/07/2013 - 21:11.Mumbai, Nov 7 : Actor Imran Khan says his next film "Bhavesh Joshi" with director Vikramaditya Motwane is set in the real world and that it has nothing to do with supernatural or sci-fi elements.
"It's not a superhero film. It has no sci-fi or supernatural elements," Imran told reporters Wednesday on the set of the seventh season of "Kaun Banega Crorepati".
"It is the story of a normal guy set in the real world. There are no fantasy elements in that film," added the actor who came to promote his ready-to-release movie "Gori Tere Pyaar Mein" on the game show.
'Gori Tere...' crew gorges on Gujarati food
Submitted by Supreet Sharma on Wed, 09/04/2013 - 19:05.Mumbai, Sep 4 : A break from a shooting schedule is always welcome, and all the more, when it's about scrumptious food! The team of "Gori Tere Pyaar Mein", which is currently in production in Bhuj, had a wonderful time gorging on authentic Gujarati food.
Director Punit Malhotra was especially in high spirits after actor Anupam Kher treated the team with the Gujarati 'thali'.
'Once Upon...' opens on impressive note
Submitted by Supreet Sharma on Fri, 08/16/2013 - 23:40.New Delhi, Aug 16 : Gangster drama "Once Upon Ay Time In Mumbai Dobaara!" has got an impressive opening, but the violence is keeping families away from watching the film, says trade analysts. "Chennai Express", meanwhile, continues to entertain families.
Balaji Motion Pictures' "Once Upon Ay Time In Mumbai Dobaara!" released in approximately 1,600 screens across the country Thursday and collected Rs. 14.2 crore from paid previews.
Ekta to repeat Imran-Sonakshi in her next?
Submitted by Gurdeep Singh Tiwana on Wed, 08/07/2013 - 20:33.Mumbai, Aug 7: Imran Khan and Sonakshi Sinha have teamed up for the first time in "Once Upon Ay Time In Mumbai Dobaara" and their chemistry has appealed to the film's producer Ekta Kapoor so much that she has apparently decided to repeat them in her next movie.
Ekta is of the opinion that Imran-Sonakshi make a lovely pair, but nothing concrete has come to play yet.
When asked, Imran said: "I am also hearing the same. I don't know of any project as of now. But Ekta has been excited about our on-screen pairing and chemistry."
Big director a great benefit: says Imran
Submitted by Gurdeep Singh Tiwana on Sat, 06/29/2013 - 22:08.Mumbai, June 29 : Actor Imran Khan has worked with Milan Luthria in "Once Upon A Time In Mumbaai Dobara" and says working with a big director is a huge benefit as he enhances your performance.
"This is the first time I am doing such a big, mainstream commercial film. I am working with such a big director for the first time and I found it to be a great benefit. The way they direct your performance and enhance it, it is such a great asset for an actor to have that support," the 30-year-old said here Friday while promoting the film at a radio station.
Actress Meera visits Imran Khan in hospital
Submitted by Pankaj Mathur on Wed, 05/15/2013 - 20:56.Islamabad, May 15 : Pakistani actress Meera, who has acted in two Indian movies, Wednesday visited cricketer-turned-politician Imran Khan in hospital where he is admitted since being injured during an election rally.
The Lollywood actress inquired about the Pakistan Tehreek-e-Insaf (PTI) chief's health, Geo News reported.
Meera later told media persons that she had inquired about Khan's health, expressed her well wishes and congratulated him on his victory in the May 11 elections.
Nawaz Sharif, Imran pleased over poll turnout
Submitted by Hardeep Sidhu on Sat, 05/11/2013 - 23:46.Islamabad, May 11 : Former Pakistani prime minister Nawaz Sharif and cricketer-turned-politician Imran Khan Saturday expressed satisfaction over the turnout in the peaceful general elections in the country.
In a message on a social network, Imran, also the chairman of Pakistan Tehreek-e-Insaf, said people voted "fearlessly" in Punjab, state-run Radio Pakistan reported.
He said that despite threats from militants, the voter turnout in Sindh and Balochistan provinces were also satisfactory.
Sharif, chairman of Pakistan Muslim League-Nawaz (PML-N) said the peaceful election was a "good omen".
QSQT should not be remade: Imran Khan
Submitted by Supreet Sharma on Tue, 04/30/2013 - 18:08.Mumbai, April 30 : Imran Khan, who cried after wathcing the climax of his uncle Aamir Khan's debut film "Qayamat Se Qayamat Tak" (QSQT) at a special screening to mark 25 years of the hit movie, says it should not be remade.
"The film is still fresh and very enjoyable. To tell you the truth, I cried during the climax of the film. Yes, I was seeing it on the big screen for the first time and it was a lot of fun," the 30-year-old told reporters post screening.
Imran to kick-off poll campaign Sunday
Submitted by Mohan Kumar Shr... on Sat, 04/20/2013 - 18:14.Islamabad, April 20 : Pakistani cricketer-turned-politician Imran Khan will Sunday launch the election campaign of his Pakistan Tehrik-i-Insaf (PTI) party, a media report said.
The general election is scheduled to be held May 11.
Imran will address rallies across the country and ask voters to cast their decision in favour of "change", the Dawn reported.
An official statement from the party said that though the campaign was to be launched April 16, an intra-party row over the distribution of poll tickets, and an attack at Imran Khan's home by the party's protesting workers resulted in the delay.
Imran, Anushka bond over coffee
Submitted by Supreet Sharma on Mon, 04/08/2013 - 18:10.New Delhi, April 8 : Imran Khan and Anushka Sharma have replaced Shahid Kapoor and Priyanka Chopra to endorse coffee brand Bru. The "Matru Ki Bijlee Ka Mandola" co-stars admit they enjoyed each other's company while shooting for the new commercial for it.
Anushka says coffee keeps her energy levels high, while for Imran, coffee often becomes a reason to bond with his friends. For now, the two actors are happy that they got to share each other's company once again after "Matru...".
Imran, Anushka to endorse coffee brand together?
Submitted by Gurdeep Singh Tiwana on Sat, 03/23/2013 - 21:43.New Delhi, March 23 : It seems Imran Khan and Anushka Sharma's pairing in "Matru Ki Bijlee Ka Mandola" is working in their favour as they are said to have signed a joint deal to promote a coffee brand.
This is the same coffee brand that was earlier endorsed by "Kaminey" couple Shahid Kapoor and Priyanka Chopra, said sources, who added that Imran and Anushka have been busy testing their coffee-making skills these days.
While shooting for the ad for the brand, their love for coffee has been quite apparent, and the duo are also said to be reading up about the different varieties of coffee. (IANS)
Imran Khan's Bangalore connect
Submitted by Gurdeep Singh Tiwana on Thu, 03/07/2013 - 14:51.Mumbai, March 7 - Actor Imran Khan, who is shooting for "Gori Tere Pyaar Mein" in Bangalore, says the city will always be special for him as that is where he spent some of his childhood years.
The 30-year-old studied at a boarding school in the city at a very young age. Being back in the city for a film makes him quite excited.
"I have spent a lot of my childhood in Bangalore and thus this city will always be very special to me," Imran said in a statement.
He has also been sharing his childhood memories with the crew.
Imran claims US drone strikes in FATA being conducted with govt's complicity
Submitted by Sarthak Gupta on Tue, 02/19/2013 - 18:36.Islamabad, Feb. 19 : Drone strikes in Federally Administered Tribal Areas (FATA) were being conducted with the government's complicity, Pakistan Tehreek-e-Insaf (PTI) Chairman Imran Khan has said.
Khan added that there would be no drone strikes and military operations if PTI comes into power
Imran Khan terms Pak govt. ''coalition of the corrupt''
Submitted by Pankaj Mathur on Mon, 01/28/2013 - 20:01.Lahore, Jan 28 : Pakistan Tehreek-e-Insaf (PTI) chief Imran Khan has said that the current setup in Pakistan is not a real democracy but a "coalition of the corrupt".
Khan said that the current government has only "looted" the citizens in the name of democracy. Khan further said the leaders criticise the judiciary for harming democracy only when it investigates their corruption, reports The Express Tribune.
The PTI chief said democracy is the only way to prosper. Speaking about the dynastic politics in the country, Imran said all political parties should hold intra-party elections to bring real leaders to the top. (ANI)
Imran Khan''s PTI rejects invitation to join ''Million March'' Qadri''s sit-in against govt.
Submitted by Sarthak Gupta on Thu, 01/17/2013 - 21:25.Lahore, Jan 17 : The Pakistan Tehrik-i-Insaaf (PTI) has rejected the invitation from Minhajul Quran International (MQI) chief, Dr Tahirul Qadri, to join his protest in Islamabad.
On Wednesday, Qadri, who along with tens of thousands of his supporters is staging a sit-in outside Parliament House, demanding an "electoral reform", had invited Imran Khan to join his dharna.
The PTI refused the invitation saying it "won''t become part of any undemocratic process", reports the Dawn. The decision was taken at a meeting of the political strategy committee of the party, chaired by Imran Khan.
Pankaj Kapur still works like a struggler: Imran
Submitted by Supreet Sharma on Thu, 01/10/2013 - 17:17.New Delhi, Jan 10 : If Imran Khan was scared to work with Pankaj Kapur in "Matru Ki Bijlee Ka Mandola", he was also bowled over by the senior actor's focus and dedication. He says that despite playing a wide range of roles, the veteran treats each new project as his first movie.
"His (Pankaj) focus and dedication are remarkable to see. The way he sits and rehearses his lines and practices his scenes are very inspiring," Imran told IANS in an interview.
'Matru...'gets U/A-certificate, Bhardwaj happy
Submitted by Supreet Sharma on Mon, 01/07/2013 - 19:14.New Delhi, Jan 7 : Vishal Bhardwaj's forthcoming rustic drama "Matru Ki Bijlee Ka Mandola" has been cleared wuth a U/A certificate by the Central Board of Film Certification (CBFC). The filmmaker is glad the movie will reach a wider audience.
"I've always wanted my films to reach out to a wider audience. Finally with 'Matru...', not restricted by the A rating, I'll be able to do so. I'd like to thank the CBFC for giving this rating as it's a bright and happy film," Bhardwaj said in a statement.
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A collection of relevant and timely media clips and resources.
Posted on January 30, 2012
On January 27, official Right-to-Carry reciprocity was recognized between West Virginia Attorney General Darrell McGraw and Kansas Attorney General Derek Schmidt. Kansas now has Right-to-Carry reciprocity with twenty-eight other states.
Kansas will now recognize valid Concealed Pistol Licenses from West Virginia, and in turn, West Virginia will recognize valid Concealed Carry Handgun Licenses from Kansas. Permit holders must comply with the laws that apply in whichever state they are traveling.
The NRA would like to thank West Virginia Attorney General Darrell McGraw and Kansas Attorney General Derek Schmidt for their assistance in this effort. To view the reciprocity agreement letter, please click here.
Right-To-Carry, concealed carry


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Monmouth County Prosecutor's Office Heroin Presenation |
Home of the F A L C O N S
One Norman J. Field Way Tinton Falls, NJ 07724 732-542-1170 Phone 732-542-5815 Fax
Click on announcements to pause the scrolling.
Effective immediately all visitors to MRHS will need to produce valid photo identification prior to entering the building. Click Here For Info on the Heroin Presentation on 3-12-2014 (pdf)
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Assessment scores, including HSPA, NJASK, PASS, SAT I, and SAT II scores are now viewable under the Assessments tab in Genesis Parent Portal. More... Genesis Parent Portal now has Spanish language support.
Screens on Genesis Parent Portal can now display in Spanish. Teacher/class/assignment data will not be translated. For assistance, please contact Mrs. Francine Reinecke, 732-542-1170, x1121, or firstname.lastname@example.com. ATTENTION PARENTS GUARDIANS AND STUDENTS
Please check students' progress on Genesis Parent Portal, especially during the midpoint of the marking period, as we no longer issue interim/progress reports. Report cards will be available through the Genesis Parent Portal. If you do not have a Genesis account, please contact Mrs. Francine Reinecke, 732-542-1170, x1121 or firstname.lastname@example.com to set up an account. If you are unable to access a computer, and need a Report Card to be mailed home to you, please contact Mrs. Gayle Fitzmaier, the Director of Counseling and Health Services, at 732-542-1170, x1130 or at email@example.com Click here to view MRHS's philosophy-mission statement (PDF)
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We've known for many months that the Hyundai Equus would get an iPad (perhaps even an iPad 2 now that the release of that model is looming) in the glove box, pre-loaded with the owner's manual and an app to handle service and other customer interaction. Today, Hyundai released a little detail about... read more
Power, efficiency, luxury--you can have it all, and the entry price is just $53,700. That's the price of the 2012 Infiniti M35 Hybrid, announced today ahead of the start of... read more February 23, 2011 by Nelson Ireson
Purists bemoan Porsche's rapid expansion into non-traditional segments, while buyers eat the cars up with ravenous glee. It's a no-brainer for the people looking to make... read more February 23, 2011 by Nelson Ireson
Earlier today Porsche took the sheet off its 2012 Panamera S Hybrid, revealing a 333-horsepower, supercharged V-6 powerplant supplemented by a 47-horsepower electric motor in... read more February 16, 2011 by Nelson Ireson
Rumors are spreading on a number of topics today, the latest being Jaguar's planned model revision/addition scheme over the next 12 years. While we take such far-reaching... read more February 15, 2011 by Nelson Ireson
Performance cars are all about performance, except when they're not. In the case of luxury-performance sedans like BMW's M5, there are numerous concessions made to comfort... read more February 15, 2011 by Nelson Ireson
Penske Automotive Group has, until now, been the exclusive distributor of the Smart brand (consisting entirely of the Fortwo minicar and its new electric variant) in the U.S... read more February 14, 2011 by Nelson Ireson
The MegaCity Vehicle (MCV) is BMW's soon-to-be-built all-electric urban wonder machine, if you buy the markting spiel. But it may be more than that. BMW's Chief Financial... read more February 14, 2011 by Nelson Ireson
The U.S. Department of Transportation (DoT) yesterday released the final results from NASA's Engineering and Safety Center's ten-month study into potential electronic causes... read more February 11, 2011 by High Gear Media Staff
Two-doors are in vogue again, it seems, with every almost every major luxury manufacturer showing off a new coupe in recent months. Mercedes-Benz joins the rolls today with... read more February 11, 2011 by Nelson Ireson
The future is electric, and BMW knows it as well as anyone despite the fact that the only EVs put out by the company have thus far been limited-distribution, lease-only... read more February 10, 2011 by Nelson Ireson
The built-for-North America 2011 Volkswagen Jetta has disappointed some, but the GLI should cure most of what ails it. Replacing the budget torsion-beam rear suspension with... read more February 8, 2011 by Nelson Ireson
Calling the Mazda Miata MX-5 "a machine which drives with all the precision of a boneless limb" is a harsh, and, among owners, enthusiasts, and the automotive press... read more February 7, 2011 by Nelson Ireson
As we trace the slow but steady progress of the 2012 McLaren MP4-12C to market, today brings a milestone: the start of regular production in the company's Technology Centre... read more February 2, 2011 by Nelson Ireson
After months of leaks, the 2012 Mercedes-Benz C63 AMG is finally official, complete with U.S. specs and imagery. Though European markets will also get a wagon, we'll only be... read more February 1, 2011 by Nelson Ireson
Late last year reports of a plug-in hybrid version of the Cadillac SRX surfaced, and though GM did not confirm them, neither did it deny such a vehicle was in the works... read more January 31, 2011 by Nelson Ireson


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The Center for International Community Health Studies (CICHS) was established in the Department of Community Medicine and Health Care at the University of Connecticut School of Medicine in 1980 with a grant from the U.S. Department of Education. The objective of CICHS was to develop a nationally recognized academic center for the study of international community health issues and to become a major educational resource for the preparation of U.S. health care professionals wishing to pursue careers in the field of international health. Over the last two decades, CICHS's work has been concentrated in three key areas: 1) training of health professionals (e.g. physicians, nurses, public health officials, family planners) from developing countries; 2) educating medical, dental, and public health students in international health through courses, practicum, clerkships and research experiences in developing countries; and 3) research on international health, with special focus in the last decade on sexual risk, HIV/AIDS and reproductive health in countries including Mauritius, Sri Lanka, and India. |
Center for International
Community Health Studies (CICHS) Department of Community Medicine & Health Care University of Connecticut School of Medicine 263 Farmington Avenue, MC 6325 Farmington, CT 06030-6325 USA Telephone: 001-860-679-1570 Facsimile: 001-860-679-5464 Last updated on December 31, 2005 Send comments or questions to: email@example.com Copyright © 2003 University of Connecticut Health Center State of Connecticut Universal Website Accessibility Policy applies. |


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Crescent Oaks Country Club Opens For Business
By East Lake Blister Staff
Published Oct 09, 2011
On Friday, September 30, 2011 the Crescent Oaks Country Club opened a new era. After more than a year being closed, and falling into disarray, Mr. William "Bill" Place purchased this magnificent property and brought it back to life.
Simultaneously, he is also the owner of two other superb golf courses, Wentworth Golf Club in Tarpon Springs and Pebble Creek, Tampa. These three clubs fly under the family-owned company, Ace Golf.
This aggregation of premier clubs provides 54-holes of golf in the Tampa Bay Area which are unable to be matched anywhere in the State of Florida and affords to associate golfers the ability to play these courses with a single telephone call for a tee time.
Crescent Oaks Country Club is a superb Semi-private golf facility, which immediately upon purchase was made available to public since it was first built two decades ago.
The memberships have been exploding and once again are becoming a focal point for those golfers who have a love for the game.
The entire 18 greens Crescent Oaks Country Club have been rebuilt, and enhanced with Platinum Paspallum Greens. These surfaces are state of the art and run fast and true.
The clubhouse, first and foremost, had to have a new roof installed, which was done immediately upon purchase. From that point on the work, inside commenced. The décor has been upgraded to reflect a history of distinguished golf that has taken place at this club.
Crescent Oaks Country Club is called the Finest Semi-private Golf Facility in Pinellas County. There is dining room, which can facilitate two to three hundred people, and if you are looking for a banquet with excellent facilities, you have stuck a hole-in-one. The scenery and view is breath taking for those special occasions.
There is a new Chef in town, Curtis Boldt, who was head chef at nearby Cypress Run Golf Club for 15 years, he retired to his home in Deadwood, Black Hills, South Dakota. Curtis was enticed to come out of retirement to work at making the Crescent Oaks Country Club dining a place where family, friends and individuals who enjoy good food come to that "special technique" which he noted for.
The course is 6914 yards long, which can be played in five different levels, it carries a Par 72, which tests the skills of the talented and of course those who want to putt on a perfect surface and those who want to spend that leisured time amongst the best.
The club is located in what we describe as the "three corners." It is located touching three counties, Pinellas, Pasco and Hillsborough. Construction is almost completed, thereby allowing 4 lane traffic to and from everywhere in the Tampa Bay area, if you care to fly in the Tampa Airport is available and
finally the people in and around the local area welcome the new team in the neighborhood. They are all pleased to see what is being done and are looking to play on this finest of clubs owned by Bill Place and Ace Golf.


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Variant of impure
not pure; specif.,
- unclean; dirty
- unclean according to religious ritual; defiled
- obscene; unchaste
- mixed with foreign matter; adulterated
- mixed so as to lack purity in color, tone, style, etc.
- characterized as by grammatical errors, unidiomatic usages, solecisms, barbarisms, foreign words or idioms, esp. when used inappropriately, etc.: said of language or speech
Origin: Classical Latin impurus
Related Forms:
- impurely adverb
- impureness noun


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Missing the Boat
Sermon shared by Dan Cormie
January 2005
Summary: Why do so many seem to miss the hour of visitation? Why do we fail to receive the good things God has for us?
Denomination: Pentecostal
Audience: General adults
About Sermon Contributor
More Sermons from Dan
30, January 2004
Dakota Community Church
Missing the Boat
When we take communion I always point this out.
Jesus came to the people who were waiting for Him and yet they missed Him.
In spite of all the attention grabbing signs, in spite of healings, in spite of miracles, in spite of raising of the dead and multiplying of food; they missed Him.
Even the over 4000 years of prophetic warning did not alert them to His appearing.
Why do so many seem to miss the hour of visitation?
Why do we fail to receive the good things God has for us?
1. Many do not highly esteem their birthright.
Genesis 25: 29-34
Once when Jacob was cooking some stew, Esau came in from the open country, famished. He said to Jacob, "Quick, let me have some of that red stew! I�m famished!" (That is why he was also called Edom.)
Jacob replied, "First sell me your birthright."
"Look, I am about to die," Esau said. "What good is the birthright to me?"
But Jacob said, "Swear to me first." So he swore an oath to him, selling his birthright to Jacob.
Then Jacob gave Esau some bread and some lentil stew. He ate and drank, and then got up and left.
So Esau despised his birthright.
Hebrews 12: 15-17
See to it that no one misses the grace of God and that no bitter root grows up to cause trouble and defile many. See that no one is sexually immoral, or is godless like Esau, who for a single meal sold his inheritance rights as the oldest son. Afterward, as you know, when he wanted to inherit this blessing, he was rejected. He could bring about no change of mind, though he sought the blessing with tears.
"The chief cause of failure and unhappiness is trading what you want most for what you want now.�" --Zig Ziglar
How often do we choose to satisfy the flesh here and now without considering the possible consequence?
How often do choose sin over the reward of righteousness?
Do you know anyone who has chosen the rewards of sickness over their birthright?
We do not realize that small things can have eternal consequences.
That stew was Esau�s for the taking. He was the big strong hunter, Jacob was momma�s boy. Esau was the heir.
As Christians we must value the benefits of our �new� birthright.
How seriously do you take the promises of God?
Mark 4: 24-25
�Consider carefully what you hear,� he continued. �With the measure you use, it will be measured to you�and even more. Whoever has will be given more; whoever does not have, even what he has will be taken from him.�
Isaiah 53: 5
But He was wounded for our transgressions, He was bruised for our iniquities; the chastisement for our peace was upon Him, and by His stripes we are healed.
1Peter 2: 25
who Himself bore our sins in His own body on the tree, that we, having died to sins, might live for righteousness--by whose stripes you were healed.
Now how do you measure those to scriptures?
Measure # 1 � Healing is not for today it passed with the apostles.
Measure # 2 � We never know what God is going to do; sometimes it is not His will to heal.
Measure # 3 � Healing is in the atonement I need to find out how to make it mine!
2. Some miss out because they are not teachable.
Luke 4: 24-30
�I tell you the truth,� he continued, �No prophet is accepted in his hometown. I assure you that there were many widows in Israel in
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Like most who use PayPlan, circumstances led us to situations where we found ourselves disabled by debt with too many creditors and an inability to keep up and satisfy every commitment (your status is irrelevent - I'm your classic middle class white collar exec who's situation unravelled from a divorce). At the end of the day, you borrowed the dosh and you owe the dosh irrespective of irresponsible lending.
PayPlan were recommended to me from the National Debt Helpline. They guided me how best to engage with the creditors in a manner that they had to acknowledge and ultimately we've been able to put an informal arrangement in place which has seen my personal debt position consistently decrease year on year. It's a wonder why we have to hit a financial crisis; personally or nationally for a PayPlan to be available. I'm sure people struggled even in the good times.
This organisation behaves responsibly, doesn't accrue a fee from your debt crisis and once your DMP is up and running you'll be far happier.
Word of warning - DMP's can lull you into a false sense of security. Remember that this is an informal non legally binding agreement. If the creditors choose not to play ball then......with PayPlan its unlikely you'll end up in this position but remain on your toes.
Only gripe - being harrassed by PPI claimant sales people.
Good luck all.
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Files | Admin
Notes: = Release Notes Ruby Setup is a fork or Minero Aokoi's setup.rb script. Whereas setup.rb had to be copied into every project that used it, Ruby Setup is a stand alone application. The API is largely the same, with a only few distinctions. Most importantly, multi-package support has been removed. Also the underlying system has been made more object-oriented, for instance, what was ToplevelInstaller is now Setup::Installer. Finally configuration files are saved to .cache/setup and metaconfig should be placed in .config/setup, rather then directly into the root project directory. I still consider this and "early" release of Ruby Setup, that is until enough people put it through it's paces. However, since it is predominantly setup.rb 3.4.1 code, and since it works well enough to install itself ;) it certainly is a usable product. Please report any problems so I can fix them ASAP. ### 4.1.0 / 2008-11-16 * 5 Major Enhancements * testing only runs if a test script if provided * cache files are now stored in .cache/setup/ * Renamed binary from rubysetup to setup.rb. * Hoping that the use of a dot in the name is not a problem on Windows. * By using setup.rb for the binary, it matches exactly the name of the old script. * Other developers could do likewise, eg. setup.py; akin to mkfs.ext3 and friends. * Added script/install as a bootstrap installer. * restored metaconfig * 2 Minor Enhancements * added test from original (needs work) * removed test/suite.rb option from testing Changes: Changes: * 7 Major Enhancements * relocated all user configuration files to meta/ and meta/setup * meta/package must exist for doc to be installed. * meta/setup/test.rb must be provided to run tests. * meta/setup/doc.rb can be provided as alternate for generating docs. * meta/setup/metaconfig.rb is now where meta-configuration goes. * documentation is installed to <system-doc-dir>/ruby-<package>/. * documentation generation shells out (for now, b/c of issues with using API) * 1 Minor Addition * Notice the setup.rb file in the project repo. Guess what that is! ;)


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Dior Cannage Shoulder Bag, Handbag of the Day
This Italian patent lambskin bag is ravishingly quilted in Dior's Cannage pattern, and not over-designed -- the shiny red is enough. While this would look great with black, we'd love to see this on the arm of a lady bundled up in a pretty white coat.
The bag features bright silvery chain links and a push-lock closure, and will be available in ecru with goldtone hardware in 2010. We love the leather detail at the top of the strap to protect your shoulders, hands and clothes from having to touch the hard metal -- how very considerate.
The Dior Cannage Shoulder Bag is available from Neiman Marcus for $1,750.00.


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Cobra Speedster Long - Vulcan 900/Classic LTReviewed by: Stacey (BikerDiva) Reviewed for: 900 Vulcan Used for: 6-12 months Ratings: Overall Rating: 5 Ease of install: 4 Value: 4 Would buy again: yes Happy with sound: 5 Review Summary: Love the sound!!!! Easy to install.....A MUST HAVE Review Pros: Review Cons: Review Improvements: Review Tools: 4 out of 5 members found this review helpful. Was this review helpful to you? |


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Mill levy to help with conservation efforts
Only a handful of people gathered to hear a presentation on a proposed quarter mill levy for the Valencia Soil and Water Conservation District last Saturday morning.
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As one of the most coveted items of the 90s, it's shocking that the Sak brand is still alive and well, but there's something about the simplicity and the craftsmanship of a Sak bag that has kept fashionistas returning for years. As the brand adapted its shapes and styles, the bags only became more popular, and Sak carved it's niche into handbag history. Now offering the classic crochet, as well as leather stylings, there's a Sak bag for nearly everyone and every design aesthetic. Opening Monday, January 23, the Sak flash sale at Beyond The Rack will present one of America's favorite handbag brands at unbeatable prices.
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Geneva Drops Second Straight, Falls at Muskingum |
Muskingum, OH – The question can now be asked if losing two straight matches prior to the start of conference play is a positive or a negative? For the first time in 2011, the Geneva College men's soccer team dropped two straight games and with the Presidents' Athletic Conference schedule set to open in three days, is it bad timing? The answer to that question will be forthcoming but at this point Geneva would like to get right back in the goal column and the win column. On Wednesday afternoon, the Golden Tornadoes dropped a 1-0 decision to Muskingum College and fell to 6-3-1 in September with a whole lot of conference action coming up in October. The loss to Muskingum follows an 8-0 defeat at the hands of Messiah on Saturday. Not only is it two straight losses but it's also two consecutive shut-outs. On Wednesday, neither team could find the net in the first half and it wasn't until the 83rd minute of the match that a through-ball fed past a flat Geneva defense resulted in a breakaway goal and proved to be the game winner. Despite Geneva out shooting Muskingum by a 2-1 ratio and Geneva having the majority of scoring changes, Muskingum made its one good chance stand up for the victory. Geneva will indeed open up PAC play on Saturday afternoon against Washington & Jefferson for a 1:30 pm kickoff. It will be the first-ever PAC game for the Golden Tornadoes since making the switch to Division III four years ago. Geneva College is a comprehensive Christian college of the arts, sciences and professional studies. Founded in the tradition of the Reformed Christian faith, Geneva prepares students to serve Christ in all areas of society: work, family and the church. Geneva College's philosophy of education is based on the Foundational Concepts of Christian Higher Education. Geneva is a founding member of the Council for Christian Colleges & Universities (CCCU). |
http://www.geneva.edu/object/io_1317252223654.html Geneva College | 3200 College Ave., Beaver Falls, PA 15010 |


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The largest privately held companies in the United States last year were:
1. Cargill, food, drink and tobacco, including Horizon Milling in Chattanooga, $133.9 billion in revenues
2. Koch Industries, conglomerate business, $115 billion in revenues
3. Mars, food, drink and tobacco, including M&M plant in Cleveland, Tenn., $70 billion in revenues
4. Bechtel, construction, including contractor for TVA, $53 billion in revenues
5. PricewaterhouseCoopers, accounting firm, $31.5 billion in revenues
6. PilotFlying J, truck stop chain based in Knoxville, $29.3 billion in revenues
7. Publix Super Markets, grocery chain with four stores in Chattanooga, $27 billion in revenues
8. Ernst & Young, accounting firm with $24.4 billion in revenues
9. Love's Travel Stops & Country Stores, $22 billion in revenues
10. C&S Wholesale Grocers, food, drink and tobacco, $21.7 billion in revenues
Source: Forbes magazine, "America's Largest Private Companies."
Dave Flessner is the business editor for the Times Free Press. A journalist for 35 years, Dave has been business editor and projects editor for the Chattanooga Times Free Press, city editor for The Chattanooga Times, business and county reporter for the Chattanooga Times, correspondent for the Lansing State Journal and Ingham County News in Michigan, staff writer for the Hastings Daily Tribune in Nebraska, and news director for WCBN-FM in Michigan. Dave, a native ...
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Visitors to this year's Riverbend Festival, which cranks up Friday, may notice a few changes to the way security is ...
Biggest employers, publicly traded companies, private companies occupations and new investments.


text:
- Getting Weird
Scents of Some Bullshit - Recently I have picked up the pencil again trying to pull away for a bit from just drawing on the computer.
This is what has come of it.
Charmed, I'm sure... - Steady Divide
- Baby Shit
- Baby Spitter
- Wolf Mountain
- Block Squirt in the Forest
- The Fatman
- Crucified Self Portrait


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Went to the Ringside (Fox Tower) for our 32nd anniversary last night. The location is beautiful and the service is great. But, the food was so exceptionally poor. I had a Read More
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Bandon is a surprising little town, with much more to offer than meets the eye. Shortly after moving here my wife and I were surprised with the quality of the restaurants Read More
We had dinner at the Pine Tavern in Bend. It is a great place to sit back and relax and enjoy some great food. There are 2 trees growing out of the building through the Read More
Showing All Restaurants


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Description : A chess site featuring tournaments, games and history as well as many fun stories about chess.
Is there any web site that we can learn the meaning of informatics terms ? Like informatics bank ?
Althought chessdom has a comprehensive content, It really works quick. Where do they nestle their web site ?
If is there anyone who has more information about this web site, We wait their sharing.
You can direct the your domains If you buy empty domains from following domain versions. As such, the man who write your web site wrong or who remember your web site wrong, can contact with you. You might decrease the possibilty of imitation of your domain. By clicking the collected buton, determine the domains who are suitable for sale and buy with a click.
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It is given on the following that the wrong searchings about your domain. You can check them and If you think you lose too many visitors, by creating subdomains about wrong searchings, you can direct the visitors to your main site and you don't lose them.


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Northrop Grumman has named Walid Abukhaled chief executive of its business in Saudi Arabia. Read More
Lockheed Martin's Marillyn Hewson will celebrate her first anniversary as CEO with the addition of another title in front of her name. The company's board has appointed her chairman of the board. Read More
Science Applications International Corp. has won a $14.4 million option to provide the Navy with technical and engineering services. Read More
Lockheed Martin has named retired Air Force Lt. Gen. Mike Hamel president of Lockheed Martin Space Systems' Commercial Ventures division. Read More
Abt Associates has named Christopher Spera vice president of the company's U.S. health division, where he will oversee the company's behavioral health, health policy and public health and epidemiology practices. Read More
SRA has tapped three executives to fill senior leadership positions as the company realigns its operating groups from four to two. Read More
Raytheon has won a $35 million option to provide the Navy with design agent engineering services for the MK-31 Rolling Airframe Missile Guided Missile Guided Missile Weapon System. Read More
Alion Science and Technology has won a $45 million task order to help the U.S. Army Rapid Equipping Force assess leading-edge technologies and bridge capability gaps to meet warfighter needs. Read More
QinetiQ North America has won a $7.8 million order to provide Pakistan with TALON robots that can help dispose of improvised explosive devices. Read More
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What's Your Number? Why Asking About Past Sexual Partners Doesn't Work
Are you a "perfect 10"?
Hey, what's your number? No, not the one to your cell phone, the other one.
It's a question so popular that many a Cosmo quiz has attempted soliciting the secret sum from their readers, and that a movie of the same title was released just last year—mostly to negative reviews—illustrating just how universal this premise might be: A woman discovers that, according to (surprise!) a magazine article, her number of past sexual partners is double that of the average, so she embarks on a hunt for long lost loves in the hopes that she's mistakenly overlooked a potential husband—all this, so she can avoid adding another notch to the proverbial belt. God forbid.
Because asking a woman for her other number is as taboo (and tacky) as inquiring about her age or weight, a dating site recently surveyed 1000 men and women in search of a slightly different figure: the perfect number of past partners they'd want their new lover to have.
Half of all women, and nearly the same percentage of men (at 46 percent), declared 10 the ideal number of past sexual partners. However, when it came to actually asking their partner the ultimate question, it appears inquiring minds really didn't want to know, and the numbers dipped. Only 35 percent of women professed wanting to know the total number of their new lover's old conquests, this compared to 30 percent of men. So, besides the curiosity factor, does the grand total ever really matter?
"It's the most pointless question of all, because it takes out the emotion, and it takes out the circumstance," relationship expert Tracey Cox told the Guardian.
Plus, who's to say that the interrogated party is being sincere about their sexual past anyway?
"I can tell you, beyond 10, most lose count and probably will not be telling the truth to their partner," said psychotherapist Edie Raether, author of "Sex for the Soul."
In fact, dishing out dishonest data is so common that the widely accepted (albeit amusing) mathematical theorem to uncovering the real number is popularly known as "The Rule of Three," or, as broken down by rapper J. Cole's lyrics: "She say she only f**ked like 4, 5 ni**as / So you know you gotta multiply by 3." (Speaking directly to the stigma attached to a lady in possession of a severely-nicked bedpost, the song was appropriately titled "Nobody's Perfect.")
It is that same stigma, however, that author Karyn Bosnak says made movie producers uncomfortable when they approached her about adapting her book "20 Times a Lady" into the aforementioned clunker that starred Anna Faris in the role of the frantic young woman. "They all wanted to make it [about] a girl who had ten boyfriends that she [just] dated, not 20 men she slept with," Bosnak told the Huffington Post.
The survey findings further support Bosnak's suggestion that men are less tolerant of women's purported promiscuity, as 43 percent of them said they'd prefer their date have carried on sexual dalliances with even less than 10 partners (compared to 36 percent of women).
"Men don't want their women to have had a lot of sex partners," said dating advice expert April Masini. "They don't want to know that you've ever had a one night stand. And they don't want you to be easy or slutty, [especially] if they see a future with you. They want to be the first, the best, the last—and if they can't be the last, they want to be the one who ruined it for you by making sex with them so good that you'll never have as fulfilling an experience again."
[Is Cheating the Ultimate Dealbreaker?]
So should couples attempt broaching this perennially awkward conversation in the first place?
"My advice is don't," said Masini. "Play the old-fashioned bad manners card. Like the number on your income tax returns, it's private."
Jason, a 25-year-old New York City bartender, agrees. Boasting a slightly lower number in lovers than birthdays, when he met a special girl, he told her his number was a third of the actual total. "I lied because I'm not proud of the number, I don't feel it represents who I am well. Plus, at the time, I didn't think I owed her—or anyone ever—an explanation of every mistake I've made and regret that I have. I also didn't want to push her away. It ultimately worked out. Years later, we're happy together and everyone else is a very, very distant memory."


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This page contains Cheats for BlocksBlast organized by sections for Mobile. BlocksBlast is a Miscellaneous Puzzle General game, made by PaletSoft Inc and published by PaletSoft Inc. If you can't find a hint or secret in our list, then please check this page periodically for the latest updates.
BlocksBlast Mobile Cheats
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- Genre: Miscellaneous Puzzle General
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Don't forget to Bookmark this page for the latest BlocksBlast Cheats. At this moment there are no cheats or walkthroughs available for BlocksBlast. If you know cheats, secrets, hints or glitches for this game then please Submit them.
Stuck on this game? Set a specific, clearly defined question and let others answer your question or view answers to previously asked questions. If you think you are an BlocksBlast expert then please try to help others with their questions.
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Healthline Blogs
Que Significa ser Padres? Parenting Advice en Espanol
Just in time for Dia de los Madres, the National Institutes of Health (NIH) is offering a free publication with Evidence-Based Parenting Guidelines. The English version, Adventures in Parenting, is also available. Call 1-800-370-2943. Llama este numero para este librito de 70 paginas para tener exito con la crianza de los ninos desde recien nacidos hasta 14 anos de edad.
One thing that is certain not to be recommended is leaving your toddlers at home alone while you go out to dinner. Parenting is a verb, and when your kids are frustrating you and you are pulling your hair out wondering what to do next, think about how tough the world is for them. Follow the advice of the basketball coach who works a second job as crew on my commuter ferry , " Love them some more."
Thank you torres21 for use of photo rioBapt 035.
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Written by Celia I. Campbell-Mohn
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environmental law
Written by Celia I. Campbell-Mohn
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Professor of Law, Vermont Law School, South Royalton. Editor of Sustainable Environmental Law: Integrating Natural Resource and Pollution Abatement Law from Resources to Recovery.
Contributions: environmental lawProfessor of Environmental Law, University of Denver, Colorado.
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Evergreen Condominiums
Travel Blogs from Keystone
Across the Contintental Divide, Again
... platform. The rain and wind were so biting that Kathy and I decided to return to the car and wait for them. The scenery and rock formations are spectacular and we saw some of the Aspen trees starting to turn golden yellow.
Leadville turned out to be a slight disappointment for us after the build-up from several sources. It's an old silver mining town with a colorful history but there's not much there for tourists ...
Greatings from Breck
... RV Resort called Tiger Run that is three miles from "Breck", as the locals call Breakenridge. It's the most modern and primped RV park we've ever seen. They planted a mature evergreen and Aspen tree in the lawn between each fully-paved pull-through.
We visited Larry and Kathy at their hotel downtown. Even though it was dusk on Sunday, Darlene and Kathy trolled the main street while Larry and I watched the Seahawks football game.
Into the Colorado Rocky Mountains
... a bad wheel bearing on the passenger side. Found a repair shop but parts won't be in until some time Wednesday. Holed up in a motel. Lucky we discovered our problem before an accident happened. Should be moving/blogging by ...
Mountain Passes and high towns
... couldn't get to the very top so stopped at Summit lake, only at 13,000ft but stunning.
In Georgetown we stopped to see the Rail-loop, made famous because the train does a loop to gain the height required. All a bit of mountain history, tied up with the mines. This small town like so many other are all so pretty, well keep, artistic and seem viable.
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FREE Email Newsletter
FCC grills Verizon on increased Early Termination Fees
December 29, 2009 5:23 am | by Jason Lomberg, Technical Editor | CommentsThe Federal Communications Commission (FCC) is investigating why Verizon Wireless doubled their Early Termination Fees for "Advanced Devices." The $350 ETF for "Advanced Devices" went into effect 11/15, and applies to PDAs and Smartphones (such as RIM Blackberries).
Army develops robotic helicopter sniper
December 29, 2009 5:13 am | by Jason Lomberg, Technical Editor | CommentsCollateral damage has become synonymous with modern urban warfare. In fact, the concept of "total war," where there is "less (or no) differentiation between combatants and non-combatants (civilians)," has existed since The Peloponnesian War. As far back as 431 BC, civilian casualties were considered an acceptable (and often desirable) outcome of total warfare.
Company unveils world's first commercial spaceship
December 29, 2009 5:04 am | by Jason Lomberg, Technical Editor | CommentsThese are the voyages of the VSS Enterprise. To ferry civilians into space. To collect $200,000 a head. To boldly go where few space tourists have gone before! On Monday, December 7th (an "infamous" date, to be sure), Virgin Galactic unveiled SpaceShipTwo, the world's first commercial spaceline.
Advanced Precision Kill Weapon System goes 4 for 4 in testing
December 29, 2009 4:45 am | by Jason Lomberg, Technical Editor | CommentsThe Advanced Precision Kill Weapon System (APKWS), a laser-guidance platform from BAE Systems, scored four hits in four shots during the final phase of testing. APKWS adds precision laser guidance capabilities to 2.75 inch rockets—specifically, those found in attack helicopters.
They're Here! Winter, Holidays, and the New Year. How Will You Save Energy?
December 22, 2009 7:53 am | by Energy Savers Blog | CommentsWinter officially hit this week, and those of you on the east coast found out in a big way. Many of you are still shoveling out while trying to take care of those last-minute holiday preparations. (I'm actually kind of jealous. I love shoveling snow. I just
Dishwasher – 1; Human – 0
December 21, 2009 8:51 am | by Energy Savers Blog | CommentsMy dishwasher and I have been locked in mortal combat for almost a month now, ever since it decided to quit working at nearly the same moment I decided to start washing the Thanksgiving dinner dishes. Over the past week it has started to look as if the dishw
SWUGN Year in Review - July 2009
December 18, 2009 7:51 am | by Richard Doyle's Community Blog | CommentsTop StoryThe SWUGN Summit - Columbus draws 105 attendees, far above the expected turnout. The event features 10 different presenters, and is represented by 5 different user groups. Many of the presenters were doing their first ever sessions, and all of them did an outstanding job. The...
SWUGN Year in Review - June 2009
December 18, 2009 5:54 am | by Richard Doyle's Community Blog | CommentsTop StoryJust over 100 people attend the SWUGN Summit - Happy Valleyin State College, PA. The amazing thing about this Summit event is how far people travel to attend. SolidWorks users from Pittsburgh (140 miles),Philadelphia (190 miles), even Rochester, NY (240 miles) make the trek to...
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December 17, 2009 4:52 am | by Energy Savers Blog | CommentsThis week, you read about an application that helps you find E85 fueling stations using popular GPS navigation units. G
SWUGN Year in Review - May 2009
December 16, 2009 7:52 am | by Richard Doyle's Community Blog | CommentsTop StoryCOSUG leader and SolidWorks user Kelly Frazier passes the patent bar exam and becomes a Registered Patent Agent. The license allows Kelly to practice patent law before the USPTO. It also gives her company (THNKtions, LLC) a leg up on the competition. Business owner, SolidWorks...
SWUGN Year in Review - April 2009
December 15, 2009 11:52 am | by Richard Doyle's Community Blog | CommentsTop StoryLou Gallo attends his first COFES conference. While most of the other attendees are talking about social media, Lou actually does social media and reports on every single thing that happens using podcasts, Twitter, blogs, and maybe even a few smoke signals. SolidWorks users...
SWUGN Year in Review - March 2009
December 15, 2009 9:52 am | by Richard Doyle's Community Blog | CommentsTop StoryRodney Hall gets in his car and drives four hours to his new job. The 300+ mile drive is nothing compared to the 16 hours he spent on the road to attend SolidWorks World in Orlando. Armed with a webcam, a Skype account, and a huge following in the SolidWorks Community,...
Looking for E85? There's an App for That
December 15, 2009 8:53 am | by Energy Savers Blog | CommentsWant to know where you can buy E85? There's an app for that now. The Renewable Fuels Association (RFA) has launched a new application for Garmin and TomTom GPS units that that ma
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General Exalted Discussion II: No Longer Mortal
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Re: General Exalted Discussion II: No Longer Mortal
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So, "The Song of the Shadow" is an Essence 10 charm that allows an Infernal to create Celestial (Solar-level, t'boot) Exalted. As many as they feel like, albeit only upon people willing to give up their free will in exchange for superpowers and not being a worthless dirt farmer anymore (I'm sure the line will be very short). This charm has six prerequisites, starting at Essence 6 and going up from there.
Where exactly would you put a charm for making essentially Terrestrial-but-using-my-third-circle-souls-instead-of-the-elemental-dragons-as-a-template Exaltations?
What about the ability to make, say, 100 shard-based Exaltations, but with the same level of power as Terrestrials?
It doesn't make Exalted. It doesn't make Exalted -at all-. It makes Akuma...and really, the difference sounds naggling, but let's look:
Mortal Akuma gain access to "You" Charms from Essence 1-3. Being an Akuma doesn't let them gain any more Essence than usual, so reaching Essence 4 requires apotheosis into a spirit, which renders the Akuma-process invalid. Yes, you can create what are effectively infinite Half-Castes...but I'm betting an Essence 10 Solar can, too. At least until Mortal Akuma and Half Castes are beaten with the nerf stick they so rightly deserve.
Terrestrials...well, you can corrupt them, give them access to Primordial level Charms. It's an upgrade, but it's not quite creating a whole new class of Exalted, given that the Yozi already have this capability in setting and haven't been able to find all that many takers.
Making Exaltations...well, it requires more than just a Charm. We're not likely to ever SEE the exact process, because it is such a big mystery of the setting and we've slaughtered most of the mysteries to begin with. But it's a task of sufficient drain and difficulty that some of the most powerful beings in existence only did it once, to a limited quantity of individuals.
So...yeah. Not really applicable.
Edit: Akuma aren't really Solar level, either. Green Sun Princes are Solar-tier by virtue of having multi-Yozi access. Primordials are Solar-tier by virtue of infinite XP and Cosmic Principle benefits. Akuma generally occupy a level a half-step above their native tier.
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Plans to renovate the Thomas Calhoun Walker Educational Center have hit a bit of a snag, with the bidding process slowed by the complexity of the project, In an update from schools and county staff on Tuesday night, the Gloucester School Board learned that complete plans, specifications and drawings will be done a week later than expected. That in turn pushes a number of other deadlines back. Bids on the project, expected to cost in the millions and still awaiting a funding decision, are due Feb. 5. That's three days after a joint meeting between the School Board and Board of Supervisors.
An officer and a suspect were shot during a traffic stop last night. Police stopped a BMW on the Interstate 664 off-ramp near Jefferson Avenue and 35th Street in Newport News just before 7 p.m., The suspect then drove away from the scene, Police exchanged gunfire with the suspect and both an officer and the man were shot. They were taken to a local hospital with non-life-threatening injuries. In addition to the criminal investigation, the professional standards division of the police department is conducting an internal investigation, which is standard in officer-involved shootings
Virginia has awarded a dozen grants totaling over one and a half million dollars to protect 1,642 acres of farm and forestland, natural areas and historic tracts. The grants aare going to Shenandoah Valley Battlefields Foundation for 92 acres of the Port Republic Battlefield, the Civil War Trust for a 1-acre property in Henrico County that was the site of the last battle of the Seven Days' Campaign, and to Sundance LLC to purchase 206 acres of forestland in Rockingham County, among others.
The U.S. Department of Energy has announced awards to speed the development of offshore wind projects, and Dominion Virginia Power is among the recipients. The grants provide up to $4 million for each recipient to complete engineering, design and other costs. The Dominion award is for two 6-megawatt turbines off Virginia Beach. Oceana's Nancy Sopko says the awards provide much-needed support to a growing and promising industry. The ocean advocate said offshore winds provide clean, renewable energy while creating thousands of jobs. The federal government plans to sell leases for wind farms off the coast of Virginia next year.
The Peace Corps says Virginia ranks ninth among states in the number of people who volunteer to serve. The program currently has 303 Virginia residents. No other states from the mid-Atlantic region placed on the top states list. Volunteer projects relate to agriculture, economic development, education, environment, health and youth development. Since the Corps' founding in 1951, more than 7,000 Peace Corps volunteers from Virginia have served in 139 countries.
Virginia will receive more than $1.2 million in a settlement with Pfizer Inc. over its marketing of drugs Zyvox and Lyrica. Attorney General Ken Cuccinelli said Wednesday that Virginia's share is part of a $42.9 million settlement between the pharmaceutical company and 32 states and the District of Columbia. The states claim that Pfizer used unfair and deceptive practices in promoting Zyvox, an antibacterial agent, and Lyrica, which is used to treat fibromyalgia. Under the settlement, Pfizer does not admit wrongdoing but says it will change how it markets Zyvox and Lyrica.


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What's your image? What secrets do you have? What parts of yourself do you keep hidden? How does your image keep you separate from other people? Do people know what you go through and what really matters in your life?
As you begin to drop the waterline and explore, your depths, consider this thought. If we investigate the word "intimacy" we find: "into"—"me"—"you"—"see." In addition to the questions above, consider these: Notice:


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Ms. Motoko Habara
Is This My Destiny?
By Motoko Habara
When I was a young girl, I was stoic and loved both physical and mental training. I was able to camp for many days in the snowy mountains. I was good at marathons and woke up early in the morning to run. Although I was a perfectionist and sometimes nervous, I was also optimistic. I placed a high value on my productivity. In high school, I had a part-time job. I worked so hard that I almost collapsed at the end of each workday. I was told by others, "You can do everything" or "I admire your hard work." I used to arrive at my place of work earlier than others. I unlocked and prepared before business hours by myself. Thinking back on all I could do then still makes me sad.
One winter day while I was working and attending university night school, I felt feverish and thought I might have caught a cold. I was 19 years old. Since then my fever has never gone down. Now I am 32. Even so, I continued to work, not worrying about the fever. Before long I had terrible malaise. Eventually I could not work and I resigned. I took part-time courses at the university. After school I went to bed about 1 a.m. and slept until 4 p.m. But I could not get up, even after all that time in bed.
My boyfriend, who liked my stoic and hardworking disposition, left me because I had changed and appeared to him to be lazy. I got a terrible clinical depression because I was shocked about being considered lazy. I was not conscious of being ill in those days, so I never thought of going to hospital and my family and friends did not let me see a doctor. I became emotional, impulsive and had a persecution complex.
I entered dental college, but was only able to attend for two weeks in the first year. After being absent from school for a year, I recovered somewhat and decided, with some anxiety, to return to school. I was late for class almost every day but I managed to graduate. I found a job and I was able to work for one year, but then I would have to take six months leave, then work again for six months. This cycle repeated over and over because of the physical demands the job required.
My symptoms didn't fall under any illness I had heard of, so I thought this was the fault of my spirit. I had been scolded and scorned. My co-workers thought I was insane. I was very surprised when one day I searched my symptoms on the Internet and found all of them on a site about chronic fatigue syndrome. I was sure I had CFS and told my family members about it. But they were only puzzled. They suggested I sleep in a room with strong sunlight or do some exercise.
In Japan, only some doctors in Osaka were familiar with and studied CFS. It is so even now. I live far from the hospital in Osaka, so I saw a doctor in the local university hospital who was said to treat CFS patients. He did various tests and a CT scan. He concluded that I had chronic fatigue syndrome. I saw him for some years. But the drugs he gave me for depression and bipolar disorder only alleviated my condition a little. The herbal treatment recommended by the Chinese doctor who examined me did not work at all. It was difficult to go to another university hospital. I could not believe the doctor who told me that I would recover in one or two years. I switched to the clinic in the neighborhood and was given only sleeping drugs. By then I had convinced myself that I wouldn't be cured and didn't go to Osaka. I tried massage, another Chinese medicine doctor and supplements.
My condition has gotten worse little by little. I often think of getting away or dying. It is impossible for me to do housework or bathe myself. I often lie in bed all day. My brain fog, which is getting worse, makes it hard to drive. I always need a walker or a wheelchair. I am happy because I am loved. I just got married. I have almost given up the idea of having a baby in the future. I sleep in a warm house with a roof over my head; I am given hot food and can buy some of the favorite things I want. If I recover from the illness, I will show my gratitude to all the people who have given me selfless love.
__________________________________ Grateful thanks to Hidehito Doyama for his help in translating Motoko's story to English. Motoko's original story in Japanese can be viewed by clicking here. We will continue to bring you more stories from CFS patients living in other countries, to share their experiences and connect our community around the world. Hidehito found the CFIDS Association on Facebook. Join us there today!
CFIDSLink is offered free-of-charge to anyone who requests it. Please help us continue being able to provide this service. Donate now.


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Last Night's Parties: Swedish House Mafia Kicks Off One Last Tour With The Black Tie Rave, Ben Pundole Launches A Hotel Life, And More!
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