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The Good, the Bad and the Ugly of the Washington Redskins' First 4 Games
By Brian Paxton ,
The Packers, Patriots, Giants and Redskins all have one thing in common: They are 2-2 after four games.
Right now, the league is wide open to anyone, and there's no reason not to think the Redskins have a shot at the playoffs in an NFC East where every team has serious flaws.
The big story has been the progression of Robert Griffin III in Mike and Kyle Shanahan's offense. He led his first game-winning drive in Tampa Bay and made it look easy. At one point, his headset cut out and he was forced to call the plays himself. The result: a 20-yard pass to Fred Davis to help set up a field goal.
The Falcons game this weekend could be a huge turning point in the season for the Redskins. If they manage to pick up a win against one of the best teams in the league, you have to think Washington will enter the conversation as a legitimate contender, despite their defensive struggles.
Here's the good, the bad and the ugly from the first four weeks of the season.
We are truly seeing something historic in Washington.
Not only is Robert Griffin III playing like an MVP, but fellow rookie Alfred Morris is on pace for 1,500 yards and 16 touchdowns on the season...as a sixth-round pick.
Even with top receiver Pierre Garçon missing most of the season with a lingering foot injury, Griffin has already posted 1,000 yards and four touchdowns, plus he has a 70% completion rate and just one interception. All that makes for a 103.2 QB rating through four weeks.
That's just half the story. Griffin has also amassed 234 yards and four touchdowns on the ground. Together, Morris and Griffin lead the NFL in rushing.
The theme of the season will be how long RGIII and company can keep this offense going. Right now, the Redskins are one of the top scoring offenses in the league, which has kept them in every game this year.
Fred Davis, Josh Morgan and Leonard Hankerson look to be coming on strong in the absence of Garçon. When he finally gets healthy, this group could hang with most passing attacks in the league. Yes, they don't have the elite number one receiver, but they have enough solid parts to compensate for that.
For as much as the offensive line was a concern coming into the season, they actually haven't been that bad. The Cowboys, by far, are worse off on the interior and Trent Williams is one of the best in the league talent-wise. Tyler Polumbus will give up some pressure, but he hasn't been abysmal.
No matter how bad the defense plays, Washington will have a chance in any game because of this group. Imagine what they could do with a middle-of-the-pack defense.
During preseason, DeAngelo Hall dubbed the secondary the "Island of Misfits" because it was made of players discarded by other teams.
For such a lack of talent at the safety position, this group has not been awful, but they're also not far off from that. Andy Dalton absolutely shredded this group for huge plays, which has been the weak point this season.
The Redskins have given up 20 plays of 20 yards or more. Only the Patriots and Buccaneers have given up more. They've also given up 8.8 yards per pass attempt, 326.2 yards per game and a league-high 11 touchdowns.
Statistically, only Tampa Bay has a worse passing defense in the league. That's not very good, and it's largely due to the play of the secondary.
Josh Wilson had a disappointing game last week against Tampa Bay, but has been pretty solid overall. Even Hall has had some great moments in coverage so far. But Madieu Williams and DeJon Gomes/Reed Doughty are giving very little help to them, and they have suffered so far.
This group has done a better job forcing interceptions this year than in seasons past, which bodes well, but the big plays cancel out any benefit they bring.
There's not much that can be done to improve this group right now, so they'll have to rely on game planning and forcing turnovers to bail them out. If they can eliminate the big play, this defense becomes infinitely better.
What happened to having one of the better pass rushes in football? This group has been virtually nonexistent so far this season. Josh Freeman had all day to find Vincent Jackson last week in Tampa Bay, and that's not something new.
Most of the big plays given up this year happened because the Redskins front seven couldn't collapse the pocket and bother the quarterback. Washington has just seven sacks this year, with Ryan Kerrigan accounting for half of those.
The secondary is not good enough to keep up with receivers for over three seconds, yet it is taking longer than that to get to the quarterback. That leads to big plays and easy completions.
The loss of Brian Orakpo and Adam Carriker is a big factor in the decline of the pass rush, but someone else has to step up and create pressure. Kerrigan is a phenomenal talent, but he can't do it alone.
The nature of this defense is to send everyone after the quarterback and pressure him into making mistakes. If there's no pressure, this defense fails.
That has happened in every game so far.
Getting a better push up front and cutting down on the time the quarterback has in the pocket will take the pressure off the secondary to play above their talent level and allow the defense to get off the field on third downs.
Better pass rush equals better defense. Bad pass rush equals bad defense.


text:
For the first time in a long time, North Carolina A&T is on equal football footing with long-time rival South Carolina State.
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Standard Delivery
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Black three quarter sleeve jersey maternity top
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text:
The City of East St. Louis FixiT Form will help us identify a problem in your area. Please complete the form below by marking the boxes which best
FREE dental, vision and medical services will be provided for uninsured, underinsured, unemployed and those who can't afford such services. T
The Police Department has implemented a photo speed program pursuant to City Ordinance 14-10001 (Defining Certain Civil Violations Enforced by
Mayor Alvin Parks on Monday has called on the city's residents to begin a petition drive asking President Barack Obama to get involved and stop


text:
Mar 04, 2014
Ten CIA grads talk about automotive design careers in three new videos
cia exhibition
Feb 14, 2014
2014 Student Independent Exhibition
Feb 28, 2014
Progressive acquires artwork by CIA instructor Dan Tranberg
cia exhibition
Mar 28, 2014
The Accident: Recent Work by Nicky Nodjoumi
2 days ago via Facebook
Rainy Saturday in Cleveland? Shake off the weather blahs at SIE, the Student Independent Exhibition, on view in CIAs Reinberger Galleries through March 15. For details, gallery hours, and list of this years award winners, go to: http://ow.ly/ultVi http://ow.ly/i/4OVK8 http://ow.ly/i/4OVPE
Feb 19, 2014
Photography major captures images on hand-blown glass
cia exhibition
Mar 28, 2014
Dinner by Design Art of the Table, and a runway show
Feb 14, 2014
Glass major wins award in Niche magazine competition
Apr 22, 2014 @ Museum of Contemporary Art Cleveland in Cleveland, OH
2014 Spring Design Show
Mar 05, 2014
3/6-9: Jon Jost in person, Bettie Page Reveals All, THe Pawnbroker & more!
Aug 20, 2013
CIA named one of the "Best in the Midwest"
cia exhibition
Apr 22, 2014
CIA Spring Runway Show
Academics . Sculpture . Courses
Christina Cassara
Professor/Co-Chair of Sculpture
Tina Cassara received a BA in urban studies, emphasis in sociology from Barnard College, Columbia University. ...more
While at CIA, you'll learn from the masters through our rigorous, world-class curriculum and connect with working professionals to begin your career.


text: One of Adobe's established programs has become even easier to navigate, giving novice and advanced users alike the ability to create the marketing pieces they need to professionally sell their products. At first glance, InDesign may seem like a program only for creating print pieces such as flyers, magazines and books. But InDesign CS6 is so much more.


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It makes sense... (don't kill me)
I'm actually somewhat happy by our draft so far.
We loaded up on free agency this year, significantly helping our LB's with AD and significantly helping our WR corps. In round 1, we signed a Safety that should help us for many years. With all that we've signed in FA, it makes sense that we would load our picks for next year (two 1st rounders, a 2nd, two 3rd rounders), as we will be worrying about contracts much more next year (and the year after) than this year. Remember guys, it's CONTINUED excellence that BB and crew strive for. We're already pretty damn good for this coming year, the FO is making sure that this team continues this excellence in the coming years. We drafted the way we did precisely because of our moves in FA. I for one am very happy to know that this team will automatically be a SB competitor for many more years. |
Re: It makes sense... (don't kill me)
bah get your happiness out of here. Dont you see the theme of this board?
Re: It makes sense... (don't kill me)
Of course it makes sense. Jeez. The glass is half empty. It's also half full. Sometimes, the BB/SP genius just smacks you in the face. Other times, "it is what it is," and that's that. They have an excellent track record over time, and you'd be nuts not to trust their judgment.
Sometimes the best thing you can say is "I'll do it tomorrow," and "I'll do it next year," which is basically what the Pats said about Round 1, with the exception of Brandon Merri-and-happy-and-stompin-like-christmas-weather. (Love that one pick, by the way - throw in his versatility with AD's, and you've got flexibility out the wazoo.) okay, rant over PFnV |
Re: It makes sense... (don't kill me)
I just got back from working out and talking to several Pats fans (and season ticket holders like myself) your view was the prevailing one.
San Fransisco is a team that took a nice step forward last year, but they still gave up over 400 points and have a pretty tough schedule. Las Vegas doesn't believe in them and neither do most of the folks I know. Turner is gone so Smith may or may not struggle- Norv is known for his smarts and calmness and how that sits with Smith will be something to watch. The Raiders third round next year should be single digits again. Meriweather is what BB looks for- talent that can play multi positions. He's a legit FS and can play the inside nickel in third down passing situations- think of Indy: taking on Gonzalez in the slot, or covering deep TE target like Dallas Clark. This is and was a no brainer if they character issue wasn't in play. |
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World Cup qualifying odds: New Zealand at Mexico
Mexico has the United States to thank for having a chance of qualifying for the 2014 World Cup as El Tri begins a home-and-home playoff against visiting New Zealand on Wednesday with Mexico as a big -520 WagerWeb favorite. The Kiwis are +1500 and a draw at +580.
Mexico last missed the World Cup in 1990 but would have if not for a gift from the Americans just to reach this stage. The U.S. scored two late goals to defeat Panama, sending the Mexicans to the playoff. Otherwise, Panama would have advanced and Mexico would have been out. Mexico played poorly during qualifying, struggling to score and finishing behind the U.S., Costa Rica and Honduras — the three earned the automatic berths from the CONCACAF region.
El Tri has gone to extraordinary measures in hopes of reaching Brazil, bringing in Miguel Herrera to handle the two-game playoff in the latest of a series of coaching changes. Herrera, the coach of the Mexican club America, has overlooked the country's Europe-based players, like Manchester United's Javier "Chicharito" Hernandez, one of the best players in the world, and is going with players from Mexico's domestic league. Ten of the 23 players called up by Herrera play for Club América, who Herrera guided to the 2013 Clausura title in the Liga MX and left comfortably in first place before taking over Mexico.
Herrera also stuck to his usual approach of naming which players will start the day before the game, confirming that Moises Munoz gets the nod in goal. The Mexico team, playing a 5-3-2 formation, will be: Munoz, Juan Carlos Valenzuela, Rafa Marquez, Francisco "Maza" Rodriguez, Miguel Layun, Paul Aguilar, Medina, Luis Montes, Carlos Pena, Oribe Peralta and Raul Jimenez.
The All Whites topped their World Cup qualification group in Oceania with six wins from as many games, to earn the two-leg date with the fourth-placed nation in CONCACAF qualifying. However, their upcoming battle on Wednesday stands in stark contrast to their most recent qualifying clash – a 2-0 win over the Solomon Islands in front of 5,600 people in Honiara. The Estadio Azteca in Mexico City has a capacity of 105,000, is perched 7,200 feet above sea level and will be packed full of locals doing their utmost to make life as uncomfortable as possible for the visiting Kiwis. All Whites captain Winston Reid will miss the clash due to an ankle injury sustained while training for Premier League club West Ham.
Further disadvantaging Ricki Herbert's side is that Mexico have lost just one qualifying match at the venue in their history – a 2-1 defeat to Costa Rica in 2001 – making New Zealand's chances of taking a lead to the second leg in Wellington the following week all the more difficult. That said, Mexico has just one win and three goals in its past four home matches.
"Arguably in my tenure and as a player, this would be the most difficult qualification game that New Zealand's ever had. So yep, there needs to be improvement," Herbert said.
A draw would be a terrific result ahead of the return fixture at Westpac Stadium, as New Zealand aims to reach consecutive World Cups for the first time. New Zealand had three draws in the group stage of the 2010 World Cup — the only side in the tournament not to lose a match — and this team is considered better.
World Cup qualifying soccer odds: Mexico at United States
It's the greatest soccer rivalry in North America on Tuesday night in Columbus, Ohio, and it's a must-win World Cup qualifying match for a desperate Mexico side, but the United States opened as a +150 WagerWeb favorite to take one more big step toward Brazil in 2014. Mexico is +205 and a draw at +220.
The Mexicans were humbled 2-1 at home by Honduras on Friday night and José Manuel de la Torre was fired as manager of Mexico's national team hours after the loss. The loss by Mexico at Azteca was only the second in 77 World Cup home qualifying games. With three matches left in qualifying, Mexico is fourth among six nations, 1 point ahead of Panama and 6 behind first-place Costa Rica, which defeated the United States, 3-1, on Friday.
The new manager is Luis Fernando Teña. He has been around for a while and is the mastermind of the greatest sports triumph of Mexican national teams: the winning of the Olympic gold medal in 2012. De la Torre, who is known as Chepo, took over Mexico's national team in 2011 and led the team to the Gold Cup title that year.
The United States saw its record unbeaten streak end by Costa Rica. Jhonny Acosta and Celso Borges scored as Costa Rica burst ahead in the first nine minutes, Joel Campbell added a goal on a late counterattack, and the Ticos beat the visiting United States. Avenging a March loss to the U.S. in a Colorado snow storm, Costa Rica ended the Americans' team-record 12-game winning streak — three short of the world mark set by Spain.
Clint Dempsey, making his 100th international appearance, converted a penalty kick in the 43rd minute for the U.S. and nearly tied it with a 20-yard shot off a post in the 56th minute. The Ticos (4-1-2) moved into first place in the final round of qualifying in North and Central America and the Caribbean with 14 points, one ahead of the U.S. (4-2-1) with three games remaining.
United States midfielder Michael Bradley has been ruled out for Tuesday's World Cup qualifier against Mexico. The U.S. will also be without striker Jozy Altidore and defenders Geoff Cameron and Matt Besler, who are suspended after picking up yellow cards against Costa Rica.
The past three home World Cup qualifiers against Mexico have been held in Columbus, where the United States has posted three consecutive 2-0 victories. The United States has never lost in nine games at Columbus Crew Stadium (6-0-3). The U.S. is undefeated (4-0-2) in six straight home qualifiers against Mexico, last losing in 1972. Overall, the USA is 16-32-13 all-time in international competition against Mexico and 5-15-6 in World Cup Qualifying. The USA's 61 previous meetings against Mexico are the most against any country in U.S. Soccer's history. Since 2000, the USA has posted an 11-5-4 record against Mexico, including a 9-2-3 record at home during that span.
World Cup qualifying odds: USA at Mexico
Off a crucial win in a blizzard over Costa Rica, the United States could take a big step toward qualifying for next year's World Cup by winning where they almost never do: at Mexico, which opened as a -180 favorite on WagerWeb.com for Tuesday's match. Check our current lines.
Mexico drew their first two matches, at home to Jamaica then away to Honduras, while the Americans lost their opening match in Honduras before battling to a 1-0 win over Costa Rica in Denver. Clint Dempsey's first-half goal was his 12th in World Cup qualifying, tying him with career scoring leader Landon Donovan atop the U.S. charts. Meanwhile, Mexico labored to a scoreless draw against Jamaica but then looked back to their best on Friday, at least for 70 minutes. Striker Javier Hernandez scored two superb goals before Honduras replied with two of their own in the last 15 minutes to snatch a 2-2 draw.
The Americans have the added weight of history against them, having never won a World Cup qualifier at the intimidating Azteca Stadium. But In the most recent meeting, the U.S. earned its first victory on Mexican soil, a 1-0 international friendly win on Aug. 15, 2012. Michael Orozco Fiscal scored his first international goal in the 80th minute and goalkeeper Tim Howard made three saves – including two late stops – en route to the historic victory. Howard remains out for now, however, due to injury.
"It won't be like the friendly we had in August, when it was a half-full stadium," said veteran DaMarcus Beasley, who plays his club soccer for Liga MX side Puebla. "This game will be 110,000, for sure. It's our biggest rival; it's a qualifying match; and they have to get a win. It's going to be a dogfight."
In addition, U.S. midfielder Jermaine Jones has been ruled out. He sprained his ankle against Costa Rica. Jones did not travel with the team to Mexico. Jones received the injury in the first half, which required two stitches during the interval. He continued play until being subbed out in the 83rd minute.
In the 100-year history of the American program, El Tri has been the Yanks' most frequent foe, holding a 32-16-12 record all time versus the Americans. The sides have become increasingly competitive over the past dozen years. Since 2000, the Yanks lead the series 11-5-3, and they also eliminated El Tri from the 2002 World Cup. But the pendulum has swung back recently — the U.S. has only one win in the adversaries' past five meetings.
In a way, the Yanks will be playing with house money in this one. With that 0-12 all-time record in qualifying matches south of the border, it's no secret that the U.S. is expected to lose. And after Mexico squandered a two-goal lead and had to settle for the tie in Honduras on Friday, suddenly all the stress is on the still-winless hosts.
Jenni Rivera Killed In Plane Crash
Singer Jenni Rivera was killed when the jet she was being shuttled in crashed just outside Monterrey, Mexico early Sunday.
The Mexican-American singer's father confirmed her death in the fatal crash, along with her publicist, lawyer, makeup artist and two pilots. Pedro Rivera told Telemundo:
"Everyone was lost."
The Learjet 25 had been due to arrive in Toluca, outside Mexico City, but aviation authorities lost contact with it around 10 minutes after takeoff. The wreckage was later found in Nuevo Leon.
It's still unclear what caused the powerful crash, but civil aviation chief Alejandro Argudín says the jet was "totally destroyed" and "almost unrecognizable." A mangled California driver's licence with Rivera's name and picture was found among the debris
Jenni, 43 and mother of five and grandmother of two, was a popular judge on Mexico's version of The Voice and recently signed on for an ABC comedy pilot about the adventures of a middle-class Mexican-American mom.
She sold more than 20 million albums worldwide and just this year won two Billboard Mexican Music Awards — one for Female Artist of the Year and the other for Banda Album of the Year for Joyas Prestadas: Banda.
Mexico Looking To Change Its Name To… Mexico
Mexico's president is making one last attempt to get the "United States" out of Mexico — at least as far as the country's name is concerned.
The country's formal name is "The United Mexican States," but few people use it.
President Felipe Calderon wants to make it simply "Mexico."
Calderon says the name was adopted in 1824 to imitate the country's northern neighbor, The United States of America.
Calderon said Thursday Mexico doesn't need to emulate anyone.
The constitutional reform would have to be approved by both houses of Congress and a majority of the country's 31 state legislatures. However, Calderon leaves office on Dec. 1.
Calderon first proposed the name change as a congressman in 2003. The bill did not make it to a vote.
Mexico's Election Authority Orders Vote Recount
Something's rotten in Enrique Peña Nieto's victory… Mexico's presidential election is looking a lot murkier than it did over the weekend after the country's election authority ordered 78,012 ballot boxes—54.5% of the total—to be reopened and recounted.
Andres Manuel Lopez Obrador, who came in second by a margin of around 7%, according to preliminary results, called for a recount after charging that the vote was plagued by irregularities. Election officials say the recount is "an exercise in openness and transparency."
Peña Nieto expressed confidence that the recount will keep his victory intact, although he now faces a long legal process before he can be declared president-elect.
On related news, the candidate's promise to break with the PRI's dirty past didn't get a good start after reports that the PRI handed out supermarket debit cards in return for votes. "It was perhaps the biggest operation of vote-buying and coercion in the country's history," a former election authority official tells the Washington Post.
22-Year-Old AP Intern Found Dead In Mexico
Armando Montano, a 22-year-old aspiring journalist who was working this summer as a news intern for AP in the Mexican capital, was found dead early Saturday
Montano's body was found in the elevator shaft of an apartment building near where he was living in the capital's Condesa neighborhood. The circumstances of his death were being investigated by Mexican authorities.
The Colorado resident arrived in Mexico City in early June after graduating from Grinnell College with a bachelor's degree in Spanish and a concentration in Latin American studies.
During his time in the bureau, Montano covered stories including the saga of nine young elephants from Namibia who wound up on an animal reserve in Mexico's Puebla state, and the shooting of three federal policemen at the Mexico City airport.
"Armando was a smart, joyful, hardworking and talented young man," said Marjorie Miller, AP's Latin America editor based in Mexico City.
"He absolutely loved journalism and was soaking up everything he could," said Miller. "In his short time with the AP, he won his way into everyone's hearts with his hard work, his effervescence and his love of the profession."
He is survived by his parents, Diane Alters and Mario Montano, of Colorado Springs, who both teach at Colorado College.
Mexicans Elect PRI Party Back To Power
It looks like Mexicans have really bad short tem memory: The party that ruled their country with an iron grip for most of the last century has sailed back into power, promising a government that will be modern, responsible and open to criticism.
Though Institutional Revolutionary Party candidate Enrique Pena Nieto's margin of victory was clear in the preliminary count from Sunday's election, it was not the mandate the party had anticipated from pre-election polls that had at times shown the youthful, 45-year-old with support of more than half of Mexico's voters.
Instead, he won 38 percent support, about 7 points more than his nearest rival, according to a representative count of the ballots, and he went to work immediately to win over the two-thirds who didn't vote for him, many of whom rejected his claim that he represented a reformed and repentant party.
"We're a new generation. There is no return to the past," he said in his victory speech. "It's time to move on from the country we are to the Mexico we deserve and that we can be … where every Mexican writes his own success story."
The PRI for 71 years ruled as a single party known for coercion and corruption, but also for building Mexico's institutions and social services. It was often accused of stealing elections, most infamously the 1988 presidential vote. But PRI governments were also known for keeping a lid on organized crime, whose battles with government and each other under Calderon have taken more than 50,000 lives and traumatized the country.
Repeating a popular belief of many Pena Nieto supporters, Martha Trejo, 37, of Tampico said, "He'll stabilize the cartels. He'll negotiate so they don't hurt innocents."
Good luck with that lady…


text:
My Casa Elisa
Your Holiday is only two steps from Venice! My Casa Elisa is an apartment located in the beautiful Riviera del Brenta. It has an entrance hall, bedroom, living room with kitchenette, spacious bathroom with tub and window. At guests' disposal to make your stay easier, washing machine and iron, towels and sheets, everything you need in the kitchen to prepare your own meals (oven, pots, plates etc..) and a free gift on arrival, as well informational materials. Please note: Cancellation policy: 72h advance notice Payment upon arrival by cash only Check in from 14.00 Check out before 11.00 Italian breakfast included Taxes included |
Availability & Rates
To view availability and prices please select dates and click 'Update Dates'Apartment Facilities & Policies
- Air Conditioning
- Bicycle parking
- Breakfast Included
- Child Friendly
- Credit Cards Not Accepted
- Free City Maps
- Free Parking
- Hair Dryers
- Iron and Ironing Board
- Kitchen
- Luggage Storage
- Non Smoking
- Pet Friendly
- Taxes included
- Towels Included
- Washing Machine
Cancellation Policy
This property has a 3 day cancellation policy. Failure to cancel within this time will result in a cancellation charge equal to the first night of your stay.Must-Read Apartment Info
This property has specific Terms & Conditions.Please note:
Cancellation policy: 72h advance notice
Payment upon arrival by cash only
Check in from 14.00
Check out before 11.00
Italian breakfast included
Taxes included
DirectionsShow MapHide Map
By car:
Along the S.S. 11 (Riviera del Brenta), in the section called Via Nazionale, in the direction of Venice-Padua about 500 meters past the center of Mira is Casa Elisa
Motorway A4:
exit 'Mira - Oriago' at the first roundabout, take the 1st exit indicating Mira, after 300 meters, at the second roundabout, take the 2nd exit, turn right, 300m to the left and straight ahead at the next roundabout and Interstate 11 that along the Brenta river, past the first traffic light, then the second and the third, keeping the main direction on the right after 500 meters you will find Casa Elisa.
S.S. Romea from Ravenna: at the roundabout at Marghera follow Mira / Riviera del Brenta, continue for about 6 km and 500 m after the center of Mira, on the right is Casa Elisa.
By bus:
Mira is reachable by bus using the ACTV, which run approximately every 15-30 minutes from Venice (Piazzale Roma), Mestre (Piazza XXVII Ottobre), Mirano (via boat), Padua (courier station, Piazzale Boschetti). The bus stops just a few meters away.
By train:
Mira is also easily accessible by train from the stations of Padua and Venice with the Milan-Venice and then you can easily arrive at the station of Mira-Mirano.
Always by train, railway Venice-Adria also stops at stations and Oriago Mira Buse.
By plane:
Venice Marco Polo International Airport, 7 km from Mestre.
Venice and Padua are easily accessible by bus, the bus stop is a short walk from the apartment and also parking in Venice are very expensive!
Located Near
From the Santa Lucia station or the airport Marco Polo the hotel is easily reachable by public transports.
The apartment is in a great location to reach in a few minutes and visit the nearby Padua and Venice and a few steps away is a bus stop.


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Hot Water Music
~ Group
Hot Water Music is a punk rock band from Gainesville, Florida. The members of the band are Chuck Ragan, Chris Wollard, Jason Black, and George Rebelo. HWM first formed in 1993. In 1998, after releasing multiple EPs and three full-length albums, the band briefly disbanded, but soon reformed, announcing their continuation as Hot Water Music at the concert recorded for Live at the Hardback. They are represented by David "Beno" Benveniste's Velvet Hammer Music and Management Group. In late 2005, Hot Water Music stated they were going on a hiatus following Chuck Ragan's departure. On May 13, 2006 however, the hiatus became permanent and Hot Water Music officially disbanded. The three remaining members have started a new project, The Draft, whose first album, In a Million Pieces, was released on September 12, 2006. Chuck Ragan also continues with a more low-key music career, releasing material through No Idea Records and Side One Dummy Records. He is currently signed to the latter. The band members have also participated in many side projects. The four most popular of these are Blacktop Cadence, Cro(w)s, Unitas and Rumbleseat.
A collection of Hot Water Music work on No Idea records has been released, titled Till the Wheels Fall Off . It was released on CD and on LP. According to Jason Black in an interview with Alternative Press, the compilation will feature "a song [called "Home"] that hasn't come out anywhere...it was one of two that didn't make it [onto The New What Next]."
The band's name was taken from the book by Charles Bukowski of the same name.
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Product Pathways - Tyrosine Kinase / Adaptors
Phospho-FGF Receptor (Tyr653/654) Antibody #3471
PhosphoSitePlus® protein, site, and accession data: FGFR1
No. | Size | Price | ||
3471S | 100 µl (10 western blots) | --- | In Stock | --- |
3471 | carrier free and custom formulation / quantity | email request |
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Application | Dilution | Species-Reactivity | Sensitivity | MW (kDa) | Source |
W | 1:1000 | Human | Endogenous | 120, 145 | Rabbit |
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting
Species predicted to react based on 100% sequence homology: Mouse, Rat.
- 3471:
- Western Blotting
Specificity / Sensitivity
Phospho-FGF Receptor (Tyr653/654) Antibody detects endogenous levels of FGF receptors only when phosphorylated at tyrosines 653/654. This antibody cross-reacts with activated PDGF receptor and insulin/IGF-I receptors.
Source / Purification
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Tyr653/654 of human FGFR-1 (the corresponding sequence is the same in FGFR-2, -3 and -4). Antibodies are purified by protein A and peptide affinity chromatography.
Western Blotting
Western blot analysis of extracts from 293 cells overexpressing human FGFR-1, untreated or calf intestinal phosphatase (CIP)-treated, using Phospho-FGF Receptor (Tyr653/654) Antibody (upper) or FGF Receptor 1 Antibody #3472 (lower). Overexpression of human FGFR-1 protein in 293 cells results in constitutive activation of the receptors (courtesy of Dr. Pamela Maher, personal communication). CIP treatment abolishes the reactivity of this antibody to FGFR-1.
Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. There are four members of the FGF receptor family: FGFR1 (flg), FGFR2 (bek, KGFR), FGFR3, and FGFR4. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766. Tyr653 and Tyr654 are important for catalytic activity of activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCγ (4,5).
Application References
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For Research Use Only. Not For Use In Diagnostic Procedures.
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