text:
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Hawaii Top Attractions
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Apple will get some ravings fpr awhile, just like android it is here to stay.
Printable View
Apple will get some ravings fpr awhile, just like android it is here to stay.
yep, i just thought 15 minutes ( i know it was used figuratively) is a little conservative. they've definitely got at least an hour of fame with this one haha...i mean its on every major news channel right now, in print, and even a forum dedicated to the droid has created a subsection for it...
haha yeah...it can get annoying to see threads everywhere about the iphone especially on a droid site, but that just shows you how big this is (as much as people want to deny it)....CES just happened and that stuff is on the backburner already (not on purpose, but because the iPhone garners that much attention no matter what it does) with the mere speculation that the iPhone is coming to VZW. EVERYONE and their mother is reporting on this, so 15 minutes is definitely a little conservative haha
Actually the reason we dedicated a section to the iphone is because we know some droid users were looking to get the device for their spouse, kid, or even themselves. You the member are important and we wanted an area to discuss it. So this section is here to stay as well...unless tomorrow att announces "sike..gotcha, we signed the new exclusive deal with apple for another 3 years" ... but we know that is not gonna happen cuz att choked it away.
of course, and i understand that. the point is, do you think iphone-centric forums are setting up subsections to discuss android? i don't know, but i would think not. it's not something wrong that droidforums did for setting this subsection up, what i'm saying is the importance of the iphone coming to VZW almost dictates that you have to set this section up. Because otherwise you'd get inundated with stories, links and people bashing the iphone or bashing android on the other areas of the site (this was what was happening before this section was set up). People were posting iphone news, rumors, links in every section of the site (and not just noobs who signed up specifically to post a link. Established members were doing this). If you delete this section, you'll get the same thing again. people are going to talk about the iphone no matter what. i applaud you guys for being open minded and allowing members to discuss it here. i just wish everyone was as open minded as the staff here...
Closed.....we have many of these threads already gentlemen.
Thank you amigos!!


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How to apply
Applications are invited from candidates who have, or expect to obtain, at least an upper second class honours degree (or equivalent qualification or experience) and who can demonstrate an interest in biomedical imaging.
To apply please:
- Complete an on-line application form. The Programme Code is TMRMBISING01 ('MRes Medical and Biomedical Imaging') for both the three and four year PhD programmes. (Note: If you follow the link above, you will be directed to a page titled "Search Programme". Once there, enter the keyword "Imaging" before clicking the search button.)
- Then, please send your application number, your CV and a covering letter explaining your motivations for applying to the programme to email@example.com.
We are accepting applications for September 2014 entry. The next deadline for submitting your applications is April 7th, 2014.
Page last modified on 03 mar 14 19:00


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I've learned that through God and the leading of the Holy Spirit I
don't have to give up in the storm, just learn to dance through the
rain with Him! He works all things together for our good when you
are in Relationship with Christ, there's nothing better! He makes
life fun and easy when we follow His lead! This is how I live to
glorify Him!
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- Graduated from university
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- Likes dogs and likes cats
- Speaks
- English (Fluently), Sign Language (Fluently)
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What I'm doing with my life
Currently a Job Developer for people with disabilities and Sign
Language Interpreter.
I'm really good at
The first things people usually notice about me
Smile and or hair
Favorite books, movies, shows, music, and food
Bible, Secret Life of Bees, Christian Worship and La Charreada
The six things I could never do without
Relationship with God
His unconditional love
Holy Spirit's Lead
The Arts
His unconditional love
Holy Spirit's Lead
The Arts
I spend a lot of time thinking about
How Good God is and that He has already blessed us---very grateful!
On a typical Friday night I am
Never a Friday night the same : )....
The most private thing I'm willing to admit
We'll save that for if we get to a date...enjoying the journey is
part of the fun!
I'm looking for
- Guys who like girls
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You should message me if
You love God with all your heart and in all your ways you
acknowledge Him that He may direct your path...and if you really
like movies, music, sports and dancing!


text:
Yago Kiladze Top 3 CW Prospect
Iv been watching some CW fights recently and iv changed my mind. I now rank Chakhkiev, Kucher and Kiladze as the top 3 prospects instead of Masternak. My biggest skepticism with Mateusz is his style of defense which will leave him vulnerable against the elite imo. Kucher and Kiladze are both very complete boxers with no glaring weaknesses and i can't say the same for Mateusz and to a lesser extent Chakhkiev.
Here is Kiladze's most recent fight against Abdoul who is a very tough gatekeeper who has gone the distance against Haye, Huck, YPH, Kucher, Masternak and HW's Perez and Towers. [ame]http://www.youtube.com/watch?v=B_N6TRcB95A[/ame] |
Re: Yago Kiladze Top 3 CW Prospect
Ive had my eye on Kiladze for a while, a well rounded boxer-puncher with good technique, hand speed & power.
Another CW prospect worth watching is Youri Kalenga, a French-Congolese wrecking machine with a monster of a left hook. |
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text:
Business Law – Claims arising from dissolved partnership properly dismissed
Where the parties' partnership did not specify a definite term or undertaking, the partnership could be dissolved by the express will of any partner.
Plaintiff is not entitled to damages following her ouster from the partnership because she did not make a capital contribution, and there were no profits to be shared.
Plaintiff Urbain and defendants Clinesmith ...


text:
Hotel Greif
Travel Blogs from Wels
How do I make this thing stop?
... flat, uninhabited spots but in the end we found a dessicated, silt river bed 5m from the Donau edge.
We went to sleep listening to the sound of awful, live Austrian pop from a nearby festival which we had cycled through just before pitching up. Read Ernest Hemingway with the ear plugs in / made me want to become an alcoholic!
My birthday!
... for us! Another night of luxury.
We had a waltz around the city running a few errands for the trip and then toured a couple of bars until we found our way back to the Belgian bar! Hard to stay away from the fruity Belgian goodness. We had their lunch time special.. Pizza, beer and a waffle!
With our wallets in mind we decided to grab a few brewskis from Lidl and got ...
Mauthausen: Austria's First Concentration Camp
... freezing, and covered in their own filth. The whole experience was humbling and eye opening. The tour guide gave us the option to not walk into the killing rooms, but even though I knew it would be disturbing and terrible, I think that sometimes seeing those things are important. I came out with more questions than answers,but it is an experience that I hope to keep with me as I go about my life.
Days 108 & 109 - A taste of home
... and small staff. The big house is a 5 minute drive past the town, up a small valley, next to a fast flowing river surrounded by tall trees. A very picturesque setting indeed. We were told that this would be one of the quieter stays of trip and judging by the size of the place, we could see why. Every time a Busabout bus pulls in, a big lunch is served and judging by the homemade lasagne offered, we were already looking forward to ...
One week
I can't believe I've been here for a week already! Time flies when you're in a new city making new friends every day. Everything is awesome... Minus the fact that I'm terribly sick, my feet were covered in blisters the first two days, I got a bug bite that made my knee swell up so much that i couldn't wear pants, and I got a ticket on the tram ...


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Ginger Baker, the iconic British rock drummer who rose to fame in the '60s, is the subject of the new documentary 'Beware of Mr Baker.' Anglophenia's Tom Brook talks to director Jay Bulger about being attacked by the eldery musician while filming.
Sir Michael Caine isn't normally associated with political…
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text:
'Fringe' star Joshua Jackson appears to grab his crotch as he leaves WonderCon after promoting the hit Fox show. Joshua was joined 'Fringe' producers and co-star John Noble at the annual comic book convention. March 18, 2012.
Hello, Future Husband of Ours. – The Berry | |
You Need To Follow These Twitter Hotties – The Berry | |
Selena Gomez Is Just Showing Off Now – Popoholic | |
Christian Grey Gets Even Sexier... – Lainey Gossip | |
Kristen Stewart Is Playing Games With Robert Pattinson – ICYDK | |
Jared Leto Proves That He's Still Sexy – Lainey Gossip |


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14 Nov 2012 | #11 |
| There's no sign in the CBS log that SFC actually ran at all. Please run the CheckSUR tool from http://support.microsoft.com/kb/947821 (you'll need to look in the details for Method 2) Then zip the CheckSUR.log and attach it to your reply. The tool can take anywhere from 5 mins to a couple of hours to run (or 'Install') depending on how much it has to do, and may exit silently - it may appear to freeze for most of that time, but be patient. |
My System Specs |
. |
14 Nov 2012 | #12 |
| The CHECK SUR tool will not run in safe mode. |
My System Specs |
15 Nov 2012 | #13 |
| I keep forgetting that OK .... Let's try an offline SFC scan. Your best option in that case is to run the CHKDSK and SFC in offline mode from a Recovery Environment boot. Reboot the computer, and tap the F8 key until you get the advanced boot menu up - one option should be 'Repair your computer'. Pick that one. Log into your normal account. You'll get a set of options - pick the Command Prompt one. At the command prompt, type DIR C:\ - if we're lucky this will bring up a listing of your normal C: drive contents, including the Program Files folder(s) and the Windows folder. If not, try D:\ or E:\ (etc. until you get the right letter) then type the following command sfc /scannow /OFFBOOTDIR=<drive>:\ /OFFWINDIR=<drive>:\Windows where <drive> is the letter you found above. Wait for the command to complete. (make a note of the response!). Once it has, type EXIT and the pick the option to reboot. Post another MGADiag report |
My System Specs |
. |
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text:
By Lincoln Feast and Thuy Ong
SYDNEY (Reuters) - It's as much a part of Australia as kangaroos, the Sydney Opera House or vegemite, and General Motors Co's
Australians have reacted with a mixture of anger, sadness and resignation to GM's pre-Christmas announcement that it will stop making cars in Australia by 2017 due to high costs and a cripplingly strong currency.
But GM and independent brand experts are confident Holden will not only survive the public relations nightmare, they expect it to endure as one of the most valuable assets GM has ever built down under.
"The fact that they're no longer made here will cause some dissatisfaction and backlash but there'll still be a lot of people who like them," said Danny Samson, professor of management at Melbourne University. "It's a very well regarded brand and there's no way you'd want to throw it away."
While a combination of a strong pipeline of new models, effective retraining for affected staff and continued investment in its distribution network would help Holden mitigate the fallout, its biggest asset will be its long and much-loved history in Australia.
As Australia rose to prosperity in the 1950s and 1960s, feeding and clothing a Europe recovering from World War 2, the vehicle it drove was the Holden ute.
The ute - short for utility vehicle - became ubiquitous in both Australia's countryside - the bush - and the suburbs, its pick-up style flat bed handy for transporting surfboards or sheep.
Holden's popularity continued to grow during the 1970s, driven by the success of its HQ series and the celebrated in its advertising campaign featuring the jingle "Football, Meat Pies, Kangaroos and Holden Cars" - an Australian version of the North American "Baseball, Hot Dogs, Apple Pies and Chevrolet" ad.
A fierce rivalry with Ford
One Holden model was even named a priceless national treasure by the National Library of Australia and the death in a 2006 rally crash of Holden racing stalwart Peter Brock, the undisputed "King of the Mountain", was a day of national mourning.
GM is adamant the Holden brand with its "lion and stone wheel" logo will remain in Australia after its two plants near Adelaide and Melbourne are closed in 2017.
"Holden is here to stay," GM Holden Chief Executive Mike Devereux said after announcing the planned production shutdown. "The brand is going to be a part of the fabric of this country for a very long time."
Even so, the costs of maintaining a separate brand in such a small and fractured market have prompted speculation that GM will eventually rebadge its imported Holdens as Chevrolets.
Holden is currently the second-best selling auto brand in Australia, with its market share of around 11 percent trailing Toyota Motor Corp's <7203.T> near-20 percent. But with more than 60 makers fighting for a market selling just over 1 million vehicles a year, Australia represents a small pie being sliced very thinly.
GM already imports the majority of the Holdens it sells in Australia, mostly from South Korea and Thailand, and may ramp up imports from such plants once Australian production halts.
Paul Nicolaides, a logistics manager at an industrial company and life-long Holden fan, said that would weigh on whether he continued to buy Holdens after 2017.
"I've been a Holden man all of my life and I've actually got the latest model, Commodore," he said. "We would have a rethink about what we would buy, (but) there's nothing else Australian anymore, with Ford gone and now Holden, where would we go?"
That highlights a broader challenge to the "Australian Made" campaign that promotes buying locally made goods but has already seen the domestic auto industry gutted and a host of other companies moving production offshore.
In October, Swedish appliance maker Electrolux AB
"What (Holden's departure) reflects first and foremost, is that Australia has become a very high-cost country," said Ian Harrison, the chief executive of Australian Made Campaign Ltd, the not-for-profit organization behind the certification and marketing tool. "There is not one thing in this country that you can't get more cheaply somewhere else."
Melbourne University's Samson questioned whether the "Made in Australia" factor had ever been particularly powerful.
"Only if the Australian product is every bit as valuable do they then say alright, I'll buy the Australian one, but in many categories, it's not that big of a deal."
Indeed, government funding for Australian Made was turned off in 1996 and the organization is now solely reliant on license fees for its green and gold kangaroo triangle for its A$2.5 million annual budget.
In the meantime, Holden fans will mourn.
"A bit sad, very sad actually, because I've been a follower of Holden with my father," said Bruce Lethborg, president of Holden Sporting Car Club of Victoria. "My father had Holdens, my very first car was a 1966 HR Holden, it's just devastating really."
(Editing by Raju Gopalakrishnan)


text:
Gambia is Good
- GIG purchases from nearly 1,000 growers, approximately 90% of whom are women.
Gambia Is Good (GiG) is a highly dynamic and innovative social enterprise, born out of a strategic partnership between Haygrove and Concern Universal. Since 2004, it has been providing market opportunities for small-scale Gambian farmers, helping them grow from subsistence farming to commercial enterprise. It has also been particularly successful in raising awareness to a wide range of people about the opportunities for small and medium sized farmers in Africa. Gambia is Good has won multiple awards based on the impact that it has made in The Gambia.
GiG is now under day to day operational control of Haygrove and Concern Universal continues its involvement as a strategic partner. Concern Universal is remaining highly active in relation to the link with farmers and wider stakeholders. Read more about the history of Concern Universal's relationship with Gambia is Good.
GIG is helping Gambian farmers achieve a sustainable living by:
- Providing links between rural areas and the tourist industry, by supplying high quality locally grown produce to hotels and restaurants.
- Advocating for sustainable tourism development, through partnerships with, for example, The Travel Foundation.
- Linking with Concern Universal and its partners to build the technical and marketing capacity of small farmers to respond to the growing market opportunity - through training, contract farming and other innovative arrangements that are in the development stages.
Development through sustainable business
GiG is...
- A horticultural sales & marketing business conceived as a partnership between Haygrove (a private UK business) and Concern Universal (an international NGO)
- A market outlet and distribution channel for small-scale Gambian farmers, helping to enable their transition from subsistence farming to commercial enterprise.
- Providing links between rural areas and the tourist industry, by supplying high quality locally grown produce to hotels and restaurants.
- An advocate for sustainable tourism development, though partnership with UK charity The Travel Foundation.
- A training and demonstration facility for both farmers and tourists, provided by the GiG Farm
GIG now purchases from nearly 1,000 growers, 90% of which are women.
These farmers are making the transition from subsistence agriculture to commercial enterprise. Women in the most rural communities, who previously had virtually no cash income, are now making up to £150 per month. Recent independent evaluation states that over the last three years, GiG growers have increased their income by an average of 500%.
Related pages
- More Information
- Gambia is Good award-winning farmer
- Pro-poor horticultural marketing enterprise
- To work hard is to achieve success
- An exploration of business and NGO perspectives on CSR, sustainable development and partnership (PDF 488 Kb)
- 'Growing for a future in The Gambia' as featured on Farmers Weekly 18 April 2008 (PDF 579 Kb)
- Strategic Consulting Report (PDF 2188 Kb)
- 'How Gambia eased its growing pains' article as featured in R-travel (PDF 946 Kb)
- The Travel Foundation flyer (PDF 3749 Kb)
You may need to download Adobe Reader to view files in PDF format.
You may need to download Microsoft viewer software to view Word, Excel or Powerpoint files.


text:
Categories > Celebrities > Panic! At The Disco > Deceiving.
Chapter 11.
4 ReviewsElevennnn. Flufff, fluff, fluff.
(#) doyleangel 2009-03-17 10:43:18 AM
Aw, cute chapter. I'm glad that Holly is excited about the baby now! And yeah for Ryan and Holly getting married!!
Have a good vacation and I look forward to the next update! -
(#) silver_stripes 2009-03-17 04:14:07 PM
OMG! How can you leave it with such a shocking ending and then not update for awhile?!?!? It was an adorable chapter and I was surprised by the quick wedding. Keep up the good work and enjoy your vacation. -
(#) CHELSEAsmile 2009-03-28 08:21:45 PM
this is AMAZING!
i cant wait for the next update.


text:
Houston >
Food & Dining > Royal Oak Bar and GrillNeighborhoods: Neartown/ Montrose, Central
Spacious bar with decent happy hour specials and an inexpensive brunch that you don't have to wait for, unlike other Montrose spots.
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Wesley Snipes is a free man… mostly. TMZ is reporting that the 50 year old film actor has been released from prison. According to the popular site, Snipes was released on April 2 and transferred to the New York CommunityCorrections Office. He will be on house arrest thereafter until July 19.
READ MORE: Click Here


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For those unable to come to campus, the Commencement and Baccalaureate Services will be broadcast live on this page. Simply visit this page at the times listed below to watch the services.
Baccalaureate: Friday, May 16th, 5 p.m.
Bachelor's and Master's Commencement: Saturday, May 17th, 10 a.m.
To join the conversation on Twitter, use the hashtag #GCCommencement.
If you are having trouble viewing the service, please contact the Center for Technology Servicesat ctsgordon.edu or 978.867.4500.


text:
Dear all: Since many of us are to become EFL teachers, I'd like to ask the experienced teachers, and the ones who've got ideas, what your favourite activity for teaching English language to
I have just had a couple of very successful lessons with my grade 8 students and I owe it all to a wonderful Web2 tool called GoAnimate.
Education for a Digital World contains a comprehensive collection of proven strategies and tools for effective online teaching, based on the principles of learning as a social process. It offers practical, contemporary guidance to support e-learning decision-making, instructional choices, as well as program and course planning, and development. Read more
Yesterday we met with Microsoft who showed us some really exciting new (and older) tools and resources they have developed.
Some have an obvious educational application while others are just very cool pieces of software! All except SenseCam are available to use now (and most are free).


text:
Professional Education
Bachelor of Science, McMaster University (2004)
Master of Science, University of Western Ontario (2006)
Doctor of Philosophy, University of Western Ontario (2011)
Pannexin1 (Panx1), a channel-forming glycoprotein is expressed in neonatal but not aged mouse skin. Histological staining of Panx1 knockout (KO) mouse skin revealed a reduction in epidermal and dermal thickness but an increase in hypodermal adipose tissue. Following dorsal skin punch biopsies, mutant mice exhibited a significant delay in wound healing. Scratch wound and proliferation assays revealed that cultured keratinocytes from KO mice were more migratory while dermal fibroblasts were more proliferative than controls. Additionally, collagen gels populated with fibroblasts from KO mice exhibited significantly reduced contraction, comparable to WT fibroblasts treated with the Panx1 blocker, probenecid. KO fibroblasts did not increase α-smooth muscle actin expression in response to TGF-β, as is the case for differentiating WT myofibroblasts during wound contraction. We conclude that Panx1 controls cellular properties of keratinocytes and dermal fibroblasts during early stages of skin development and modulates wound repair upon injury.Journal of Investigative Dermatology accepted article preview online, 12 February 2014; doi:10.1038/jid.2014.86.
View details for DOI 10.1038/jid.2014.86
View details for PubMedID 24522432
High throughput sequencing technologies have become essential in studies on genomics, epigenomics, and transcriptomics. Although sequencing information has traditionally been elucidated using a low throughput technique called Sanger sequencing, high throughput sequencing technologies are capable of sequencing multiple DNA molecules in parallel, enabling hundreds of millions of DNA molecules to be sequenced at a time. This advantage allows high throughput sequencing to be used to create large data sets, generating more comprehensive insights into the cellular genomic and transcriptomic signatures of various diseases and developmental stages. Within high throughput sequencing technologies, whole exome sequencing can be used to identify novel variants and other mutations that may underlie many genetic cardiac disorders, whereas RNA sequencing can be used to analyze how the transcriptome changes. Chromatin immunoprecipitation sequencing and methylation sequencing can be used to identify epigenetic changes, whereas ribosome sequencing can be used to determine which mRNA transcripts are actively being translated. In this review, we will outline the differences in various sequencing modalities and examine the main sequencing platforms on the market in terms of their relative read depths, speeds, and costs. Finally, we will discuss the development of future sequencing platforms and how these new technologies may improve on current sequencing platforms. Ultimately, these sequencing technologies will be instrumental in further delineating how the cardiovascular system develops and how perturbations in DNA and RNA can lead to cardiovascular disease.
View details for DOI 10.1161/CIRCRESAHA.113.300939
View details for PubMedID 23743227
In the present review, we provide an overview of connexin expression during skin development and remodeling in wound healing, and reflect on how loss- or gain-of-function connexin mutations may change cellular phenotypes and lead to diseases of the skin. We also consider the therapeutic value of targeting connexins in wound healing.
View details for DOI 10.1152/physiol.00058.2012
View details for PubMedID 23636264
Human-induced pluripotent stem cells (hiPSCs) have received enormous attention because of their ability to differentiate into multiple cell types that demonstrate the patient's original phenotype. The use of hiPSCs is particularly valuable to the study of cardiac biology, as human cardiomyocytes are difficult to isolate and culture and have a limited proliferative potential. By deriving iPSCs from patients with heart disease and subsequently differentiating these hiPSCs to cardiomyocytes, it is feasible to study cardiac biology in vitro and model cardiac diseases. While there are many different methods for deriving hiPSCs, clinical use of these hiPSCs will require derivation by methods that do not involve modification of the original genome (non-integrative) or incorporate xeno-derived products (such as bovine serum albumin) which may contain xeno-agents. Ideally, this derivation would be carried out under chemically defined conditions to prevent lot-to-lot variability and enhance reproducibility. Additionally, derivation from cell types such as fibroblasts requires extended culture (4-6 weeks), greatly increasing the time required to progress from biopsy to hiPSC. Herein, we outline a method of culturing peripheral blood mononuclear cells (PBMCs) and reprogramming PBMCs into hiPSCs using a non-integrative Sendai virus.
View details for DOI 10.1007/978-1-62703-511-8_7
View details for PubMedID 23807788
Pannexin 1 (Panx1) is a channel-forming glycoprotein expressed in different cell types of mammalian skin. We examined the role of Panx1 in melanoma tumorigenesis and metastasis since qPCR and Western blots revealed that mouse melanocytes exhibited low levels of Panx1 while increased Panx1 expression was correlated with tumor cell aggressiveness in the isogenic melanoma cell lines (B16-F0, -F10, and -BL6). Panx1 shRNA knockdown (Panx1-KD) generated stable BL6 cell lines, with reduced dye uptake, that showed a marked increase in melanocyte-like cell characteristics including higher melanin production, decreased cell migration and enhanced formation of cellular projections. Western blotting and proteomic analyses using 2D-gel/mass spectroscopy identified vimentin and ?-catenin as two of the markers of malignant melanoma that were down-regulated in Panx1-KD cells. Xenograft Panx1-KD cells grown within the chorioallantoic membrane of avian embryos developed tumors that were significantly smaller than controls. Mouse-Alu qPCR of the excised avian embryonic organs revealed that tumor metastasis to the liver was significantly reduced upon Panx1 knockdown. These data suggest that while Panx1 is present in skin melanocytes it is up-regulated during melanoma tumor progression, and tumorigenesis can be inhibited by the knockdown of Panx1 raising the possibility that Panx1 may be a viable target for the treatment of melanoma.
View details for DOI 10.1074/jbc.M112.377176
View details for Web of Science ID 000308074600084
View details for PubMedID 22753409
Transient knock-down of the gap junction protein Cx43 by antisense and siRNA, or gap junction block with mimetic peptides, have been shown to enhance epidermal wound healing. However, patients with oculodentodigital dysplasia (ODDD) express mutant Cx43 that leads to a chronic reduction in gap junctional intercellular communication. To determine whether mutant Cx43 in keratinocytes would impact upon the wound healing process, we localized Cx43 in human and mouse skin tissue expressing mutant Cx43 and assessed the ability of primary keratinocytes derived from a mouse model of ODDD to proliferate, migrate and differentiate. In the epidermis from an ODDD patient and in the epidermis of mice expressing the G60S mutant or in keratinocytes obtained from mutant mice, Cx43 was frequently found within intracellular compartments and rarely localized to punctate sites of cell-cell apposition. Primary keratinocytes derived from G60S mutant mice proliferated faster but migrated similarly to keratinocytes derived from wild-type control mice. Keratinocytes derived from mutant mice expressed abundant Cx43 and higher levels of involucrin and loricrin under low calcium conditions. However, after calcium-induced differentiation, similar levels of Cx43, involucrin and loricrin were observed. Thus, we conclude that during wound healing, mutant Cx43 may enhance keratinocyte proliferation and promote early differentiation of keratinocytes.
View details for DOI 10.1111/j.1600-0625.2012.01532.x
View details for Web of Science ID 000306222700009
View details for PubMedID 22775996
Patients expressing mutations in the gene encoding the gap junction protein Cx43 suffer from a disease called oculodentodigital dysplasia (ODDD). Patients with ODDD are often reported to develop hair that is dry, dull, sparse, and slow growing. To evaluate the linkage between Cx43 and hair growth, structure, and follicle density we employed a mouse model of ODDD that harbors a Cx43 G60S point mutant. Regionally sparse and overall dull hair were observed in mutant mice compared with their wild-type (WT) littermates. However, histological analysis of overall hair follicle density in mutant and WT mice did not reveal any significant differences. After epilation, mutant mouse hair grew back slower, and hair growth was asynchronous. In addition, ultrastructural scanning electron microscopic imaging of hair fibers taken from mutant mice and two patients harboring the G143S mutation revealed severe cuticle weathering. Nodule formation was also observed in the proximal region of hair fibers taken from mutant mice. These results suggest that the G60S mutant mouse model mimics the hair phenotype found in at least some ODDD patients and suggests an important role for Cx43 in hair regeneration, growth, and cuticle formation.
View details for DOI 10.1038/jid.2011.183
View details for Web of Science ID 000296240100013
View details for PubMedID 21716323
Oculodentodigital dysplasia (ODDD) is primarily an autosomal dominant human disease caused by any one of over 60 mutations in the GJA1 gene encoding the gap junction protein Cx43. In the present study, wound healing was investigated in a G60S ODDD mutant mouse model and by using dermal fibroblasts isolated from two ODDD patients harboring the p.D3N and p.V216L mutants along with dermal fibroblasts isolated from their respective unaffected relatives. Punch biopsies revealed a delay in wound closure in the G60S mutant mice in comparison to wild-type littermates, and this delay appeared to be due to defects in the dermal fibroblasts. Although both the p.D3N and p.V216L mutants reduced gap junctional intercellular communication in human dermal fibroblasts, immunolocalization studies revealed that Cx43 gap junctions were prevalent at the cell surface of p.D3N expressing fibroblasts but greatly reduced in p.V216L expressing fibroblasts. Mutant expressing fibroblasts were further found to have reduced proliferation and migration capabilities. Finally, in response to TGF?1, mutant expressing fibroblasts expressed significantly less alpha smooth muscle actin suggesting they were inefficient in their ability to differentiate into myofibroblasts. Collectively, our results suggest that ODDD patients may have subclinical defects in wound healing due to impaired function of dermal fibroblasts.
View details for DOI 10.1002/humu.21472
View details for Web of Science ID 000288464100018
View details for PubMedID 21305658
Although there are currently 62 mutants of Cx43 (connexin43) that can cause ODDD (oculodentodigital dysplasia), only two mutants have also been reported to cause palmar plantar hyperkeratosis. To determine how mutants of Cx43 can lead to this skin disease, REKs (rat epidermal keratinocytes) were engineered to express an ODDD-associated Cx43 mutant always linked to skin disease (fs260), an ODDD-linked Cx43 mutant which has been reported to sometimes cause skin disease (fs230), Cx43 mutants which cause ODDD only (G21R, G138R), a mouse Cx43 mutant linked to ODDD (G60S), a non-disease-linked truncated Cx43 mutant that is trapped in the endoplasmic reticulum (Delta244*) or full-length Cx43. When grown in organotypic cultures, of all the mutants investigated, only the fs260-expressing REKs consistently developed a thinner stratum corneum and expressed lower levels of Cx43, Cx26 and loricrin in comparison with REKs overexpressing wild-type Cx43. REKs expressing the fs260 mutant also developed a larger organotypic vital layer after acetone-induced injury and exhibited characteristics of parakeratosis. Collectively, our results suggest that the increased skin disease burden exhibited in ODDD patients harbouring the fs260 mutant is probably due to multiple additive effects cause by the mutant during epidermal differentiation.
View details for DOI 10.1042/BJ20100155
View details for Web of Science ID 000280625400006
View details for PubMedID 20515445
Pannexin (Panx) 1 and Panx3 are integral membrane proteins that share some sequence homology with the innexin family of invertebrate gap junctions. They are expressed in mammalian skin. Pannexins have been reported to form functional mechanosensitive single-membrane channels, but their importance in regulating cellular function is poorly understood. In this study, Panx1 and Panx3 were detected in the epidermis of 13.5 day embryonic mice. Compared with newborn mice, there was less Panx1 expression in both thin and thick murine skin, whereas Panx3 expression was unchanged. To investigate the role of pannexins in keratinocyte differentiation, we employed rat epidermal keratinocytes (REKs) that have the capacity to differentiate into organotypic epidermis, and engineered them to overexpress Panx1, Panx1-GFP or Panx3. The expression of Panx1 or Panx3 resulted in the increased ability of REKs to take up dye, suggesting that cell-surface channels were formed. Compared with monolayer REKs, endogenous Panx1 levels remained unchanged, whereas the 70 kDa immunoreactive species of Panx3 was greatly increased in the organotypic epidermis. In monolayer cultures, ectopic Panx1 and Panx1-GFP localized to the plasma membrane, whereas Panx3 displayed both intracellular and plasma-membrane profiles. Although both pannexins reduced cell proliferation, only Panx1 disrupted the architecture of the organotypic epidermis and markedly dysregulated cytokeratin 14 expression and localization. Furthermore, ectopic expression of only Panx1 reduced the vital layer thickness of the organotypic epidermis. In summary, Panx1 and Panx3 are coexpressed in the mammalian epidermis, and the regulation of Panx1 plays a key role in keratinocyte differentiation.
View details for DOI 10.1242/jcs.056093
View details for Web of Science ID 000276568200019
View details for PubMedID 20332104
Pannexins (Panx) are a class of integral membrane proteins that have been proposed to exhibit characteristics similar to those of connexin family members. In this study, we utilized Cx43-positive BICR-M1R(k) cells to stably express Panx1, Panx3, or Panx1-green fluorescent protein (GFP) to assess their trafficking, cell surface dynamics, and interplay with the cytoskeletal network. Expression of a Sar1 dominant negative mutant revealed that endoplasmic reticulum to Golgi transport of Panx1 and Panx3 was mediated via COPII-dependent vesicles. Distinct from Cx43-GFP, fluorescence recovery after photobleaching studies revealed that both Panx1-GFP and Panx3-GFP remained highly mobile at the cell surface. Unlike Cx43, Panx1-GFP exhibited no detectable interrelationship with microtubules. Conversely, cytochalasin B-induced disruption of microfilaments caused a severe loss of cell surface Panx1-GFP, a reduction in the recoverable fraction of Panx1-GFP that remained at the cell surface, and a decrease in Panx1-GFP vesicular transport. Furthermore, co-immunoprecipitation and co-sedimentation assays revealed actin as a novel binding partner of Panx1. Collectively, we conclude that although Panx1 and Panx3 share a common endoplasmic reticulum to Golgi secretory pathway to Cx43, their ultimate cell surface residency appears to be independent of cell contacts and the need for intact microtubules. Importantly, Panx1 has an interaction with actin microfilaments that regulates its cell surface localization and mobility.
View details for DOI 10.1074/jbc.M109.082008
View details for Web of Science ID 000275553700064
View details for PubMedID 20086016
The epidermis is a complex tissue composed principally of differentiated keratinocytes that form a keratinized stratified squamous epithelium. The gap junction proteins, connexins (Cx), are differentially expressed throughout the stratified layers of the epidermis and their exquisite regulation appears to govern the delicate balance between cell proliferation and differentiation in normal skin homeostasis and in wound healing. In the last 10 years, germ line mutations in the genes encoding five connexin family members have been linked to various types of skin diseases that appear to offset the balance between keratinocyte differentiation and proliferation. Consequently, in order to determine how these connexin gene mutations manifest as skin disease, disease-linked mutants must be expressed in 3D organotypic epidermis reference models that attempt to mimic the human condition. Given the complexity of organotypic epidermis, confocal optical and biochemical dissection of connexin or disease-linked connexin mutants within the regenerated epidermal layer is required. The procedures necessary to assess the architectural characteristics of genetically modified organotypic epidermis and its state of differentiation will be described in this chapter.
View details for DOI 10.1007/978-1-60761-380-0_22
View details for PubMedID 19908013
Connexin 43 (Cx43) is a dynamic molecule, having a short half-life of only a few hours. In this study, we use fluorescent-protein-tagged Cx43 variants to examine Cx43 delivery to the cell surface, its residency status in various cell-surface membrane domains and its mobility characteristics. Rapid time-lapse imaging led to the identification of Cx43 being delivered to cell-surface domains that lacked a contacting cell, and also to its localization within membrane protrusions. Fluorescence recovery after photobleaching (FRAP) was used to investigate the mobility state of cell-surface-localized Cx43. Cx43 mobility within clustered cell-surface profiles of Cx43 could be categorized into those with generally a high degree of lateral mobility and those with generally a low degree of lateral mobility. Cx43 mobility was independent of cluster size, yet the C-terminal domain of Cx43 regulated the proportion of gap-junction-like clusters that acquired a low Cx43 mobility state. Collectively, these studies show that Cx43 establishes residency at all cell-surface membrane domains, and progressively acquires assembly states that probably reflect differences in either channel packing and/or its interactions with Cx43-binding proteins.
View details for DOI 10.1242/jcs.036970
View details for Web of Science ID 000263071700014
View details for PubMedID 19174466
More than 40 mutations in the GJA1 gene encoding connexin43 (Cx43) have been linked to oculodentodigital dysplasia (ODDD), a pleiotropic, autosomal dominant disorder. We hypothesized that even with a significant reduction in the levels of Cx43 in a mutant mouse model of ODDD (Gja1(Jrt/+)) harbouring a G60S mutation (Cx43(G60S)), cardiomyocyte function may only be moderately compromised given that a majority of mutant mice typically survive.Western blotting and quantitative reverse transcriptase-polymerase chain reaction in conjunction with immunofluorescence were used to assess the expression and localization of Cx43 in hearts and cultured cardiomyocytes from wild-type and Gja1(Jrt/+) mice. Dye-coupling and dual whole cell patch-clamp recordings were also used to assess the gap junction channel status in cultured cardiomyocytes from wild-type and mutant mice. Cardiac tissue from adult Gja1(Jrt/+) mice revealed a 60-80% reduction in Cx43 protein with a preferential loss of the highly phosphorylated forms of Cx43. Compensation via the up-regulation of Cx40 or Cx45 was not observed. Immunofluorescent analysis of cultured cardiomyocytes revealed a trafficking defect, with a decrease in Cx43 plaques and a large population of Cx43 being retained in the Golgi apparatus. However, cultured cardiomyocytes from mutant mice remained beating with a 50% decrease in coupling conductance.These results suggest that the Cx43(G60S) mutant impairs normal trafficking and function of co-expressed Cx43 with no dramatic effect on cardiomyocyte function, suggesting that Cx43 is biosynthesized in excess of an essential need.
View details for DOI 10.1093/cvr/cvn203
View details for Web of Science ID 000260973500011
View details for PubMedID 18678643


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Western PA Man Charged With Growing Pot On Church Property
GROVE CITY, Pa. (AP) — Police say a western Pennsylvania man has been arrested and charged with growing marijuana on a church's property.
State police arrested 28-year-old Jason Como on Saturday after the Beloved Disciples Church reported that two suspected marijuana plants were growing on their property in Grove City, about 60 miles north of Pittsburgh.
Authorities found a small path that led from the plants to the backyard of a nearby home. They contacted Como and say he confessed to growing the plants.
Como was charged with manufacturing and cultivating a controlled substance and possession of drug paraphernalia.
Court papers don't list an attorney for Como, and a phone number for him couldn't immediately be located.
(© Copyright 2012 The Associated Press. All Rights Reserved. This material may not be published, broadcast, rewritten or redistributed.)
- PHOTOS: Ladies Of Monster Mania Con
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Beyond the crisis: revisiting emerging Europe's growth model
Focusing on the nexus between economic growth and the buildup of external vulnerabilities, this paper provides a systematic account of different growth strategies followed in Central and Eastern Europe in 2000-08 and then uses this growth diagnostics to derive implications for a post-crisis recovery. The main findings point to three policy lessons for improving growth sustainability. First, greater reliance on tradable sectors should be the cornerstone of a future growth model. Second, enhancing domestic sources of bank credit funding would contribute to the mitigation of external vulnerabilities and make the domestic financial system more resilient to global financial shocks. Third, prudential and macroeconomic policies will have to be more proactive in managing capital inflows, including funneling these inflows into investment in export-oriented industries.Download Info
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Article provided by Institute of Public Finance in its journal Financial Theory and Practice.
Volume (Year): 34 (2010)
Issue (Month): 4 ()
Pages: 329-356
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Keywords: sustainable economic growth; sources of growth; external vulnerabilities;References
References listed on IDEASPlease report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Stefania Fabrizio & Daniel Leigh & Ashoka Mody, 2009.
"The second transition: Eastern Europe in perspective,"
European Economy - Economic Papers
366, Directorate General Economic and Monetary Affairs (DG ECFIN), European Commission.
- Daniel Leigh & Stefania Fabrizio & Ashoka Mody, 2009. "The Second Transition: Eastern Europe in Perspective," IMF Working Papers 09/43, International Monetary Fund.
- Benjamin F. Jones & Benjamin A. Olken, 2005.
"The Anatomy of Start-Stop Growth,"
NBER Working Papers
11528, National Bureau of Economic Research, Inc.
- Benjamin F. Jones & Benjamin A. Olken, 2008. "The Anatomy of Start-Stop Growth," The Review of Economics and Statistics, MIT Press, vol. 90(3), pages 582-587, August.
- Ben Gardiner & Ron Martin & Tyler Peter, 2004. "Competitiveness, Productivity and Economic Growth across the European Regions," ERSA conference papers ersa04p333, European Regional Science Association.
- Philip Schellekens & Rudolfs Bems, 2007. "Finance and Convergence: What's Ahead for Emerging Europe?," IMF Working Papers 07/244, International Monetary Fund.
- Jesmin Rahman, 2010. "Absorption Boom and Fiscal Stance: What Lies Ahead in Eastern Europe?," IMF Working Papers 10/97, International Monetary Fund.
- An, Galina & Iyigun, Murat F., 2004. "The export skill content, learning by exporting and economic growth," Economics Letters, Elsevier, vol. 84(1), pages 29-34, July.
- Crespo Jorge & Martín Carmela & Velázquez Francisco J, 2004. "The Role of International Technology Spillovers in the Economic Growth of the OECD Countries," Global Economy Journal, De Gruyter, vol. 4(2), pages 1-20, December.
- Alexander Klemm, 2009.
"Causes, Benefits, and Risks of Business Tax Incentives,"
IMF Working Papers
09/21, International Monetary Fund.
- Alexander Klemm, 2010. "Causes, benefits, and risks of business tax incentives," International Tax and Public Finance, Springer, vol. 17(3), pages 315-336, June.
- Abdul Abiad & Ashoka Mody & Susan Schadler & Daniel Leigh, 2007. "Growth in the Central and Eastern European Countries of the European Union," IMF Occasional Papers 252, International Monetary Fund.
- Ceyla Pazarbasioglu & Gudrun Johnsen & Paul Louis Ceriel Hilbers & Inci Ötker, 2005. "Assessing and Managing Rapid Credit Growth and the Role of Supervisory and Prudential Policies," IMF Working Papers 05/151, International Monetary Fund.
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A search engine that relies heavily on a human edited directory will always beat one that relies purely on bots. And to "rely heavily" doesn't mean you need to do a 100% good job. A search engine that uses a directory that is up to date 20% of the time is going to produce higher quality results in general. More to the point of thread, why on earth would they get rid of the Directory? LOL. It just sits there, basically out of the way, making some bucks. "Hey Boss, this Directory thing is only making us a few million bucks, let's get rid of it."
Human edited directories are the wave of the future, not the past. You really have to have been in a coma or something to not notice the amount of utter drivel being put out on the Internet that *appears* to a bot to be of value, but is just quasi-mirrors, doorways and gibberish content. In contrast, the best results for any search feature sites from a well-edited directory. The directory problem is the mass scale, and whether it is profitable to make good search results. But the public has spoken clearly on this point... they like high quality results. They don't like who-pays-the-most results or who-knows-the-tricks-best results.


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· Each team shall consist of five (5) players and may begin a game with as few as four
(4) players.· A game shall continue if a team drops below four (4) players, however if a team
drops down to two (2) players, the referee shall allow the game to continue only if· All players must check in using a valid Photo ID.
· Players must check in at the scorer's table prior to entering the game. The official's
will call the players onto the court to substitute during dead balls only.


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Please note that the Library will be closed on Sunday, November 11, 2012 for Remembrance Day. Will you be attending one of the city's Remembrance Day ceremonies? Here is a link to ceremonies taking place across the city:
My grandfather is a World War II veteran, so Remembrance Day always has special meaning for me and my family. My grandpa was a Flight Sergeant with Squadron 412 of the Royal Canadian Air Force from 1939-1945. He has a brick in his name at Juno Beach, and in 2009 he appeared in a documentary about Canada's veterans, called Canada Remembers, where he was one of five WWII veterans interviewed. He just celebrated his 91st birthday in Saskatoon last month!
Come into the Library for books, DVDs, magazine articles, and electronic resources about Remembrance Day, previous wars, conflicts and peacekeeping missions. Whether it's information, a memoir, historical fiction, war poetry, or children's material you're looking for, we can help you find it.


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Attorney Hal Ostrow Selected For List Of Top Rated Lawyers In Michigan
Hal Ostrow, a Michigan based lawyer who practices Business/Corporate Law has been named a top attorney in Michigan.
GRAND RAPIDS, Mich., Oct. 7, 2013 /PRNewswire-USNewswire/ -- The 2013 list of top rated attorneys in Michigan as published in the September, 2013 issue of Crain's Detroit Business includes Hal Ostrow of Grand Rapids, Michigan for the practice of Business/Corporate Law. This distinction is given to only a very small percentage of Grand Rapids's attorneys each year.
(Photo: http://photos.prnewswire.com/prnh/20131007/DC93073)
Attorneys are only considered for inclusion in the list of top rated attorneys if they have attained a high degree of peer recognition and professional achievement across 12 indicators. Lawyers cannot buy their way onto the list. The selection process, recognized as legitimate by bar associations and courts across the United States, is multi-phased and includes independent research, peer nominations and peer evaluations. Only attorneys who can be retained by the general public are considered. Honorees are selected annually for each state and practice area.
Hal Ostrow commented on the recognition: "Michigan has so many excellent lawyers, it is an honor to be included in Crain's Detroit Business's list of top rated attorneys for 2013. I am grateful to my peers for their nomination."
About Hal Ostrow, a short profile by and about the honoree:
Attorney Hal Ostrow has helped form dozens of companies throughout Michigan and routinely offers counsel to startups, tech companies, and other business owners on a broad spectrum of matters ranging from formation to angel and venture capital funding to interaction with third parties to merger and acquisition. The Ostrow Law Firm PLC's unique subscription plans, through which clients pay a flat fee every month for a specific amount of services, reduces a significant barrier to entry for startups and provides businesses of all sizes cost certainty for award-winning legal counsel.
The plaque shown here commemorates Ostrow's recognition.
To find out more or to contact attorney Hal Ostrow of Grand Rapids, Michigan please call 616-920-1780 or visit www.ostrowlawfirm.com.
Following the announcement of Hal Ostrow's selection for Crain's Detroit Business's list of top attorneys in Michigan, American Registry seconded the honor and added Hal Ostrow to The Registry™ of Business Excellence. American Registry, LLC, recognizes excellence in top businesses and professionals. For more information, search The Registry™ at http://www.americanregistry.com.
This press release was written by American Registry, LLC, with approval by and/or contributions from Hal Ostrow and was distributed by PR Newswire, a subsidiary of UBM plc.
Contact Information:
Hal Ostrow
Phone: 616-920-1780
Email Address: email@example.com
SOURCE American Registry


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This entry was posted by mm on January 14, 2011 at 5:32 am, and is filed under News. Follow any responses to this post through RSS 2.0.You can leave a response or trackback from your own site.
Workshop 5* a cargo do Mauricio Martins !! O que se podia pedir mais? Os circuitos ficaram a "piscar", ninguem se queimou e certamente houve alguns que ficaram ainda com mais vontade de entrar nisto do "tinkering" :)
Mauricio, vamos lá organizar os outros workshops por módulos…acho que temos tudo para não parar mais ;)
altLab is a Portuguese hacklab located in Lisbon, Portugal. We're dedicated to multidisciplinary experimentalism in digital media art.Everyone is welcome to show up at our meetings and be encouraged to join us.We meet every Tuesday 8.30pm atPraceta Domingos Rodrigues, nº2.
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Shopping in Rio de Janeiro can be a rewarding experience for tourists on the hunt for bargains, whether they're seeking cheap souvenirs or designer goods. While it isn't considered a major shopping destination, there are numerous shopping centres, boutiques, street stalls and markets offering a wide selection of mementos.
Rio's main shopping destinations are concentrated into areas like Rio Sul in the city centre. There are also numerous shopping districts near the beaches, including Avenida Nossa Senhora and Rua Barata Ribeiro in Copacabana, Avenida Ataulfo de Paiva in Leblon, and Rua Visconde de Pirajá in Ipanema.
Religious antiques, soapstone carvings, leather goods and gemstone jewellery are Rio's most popular souvenirs, offered by various shops throughout the city. You can also find local gemstones carved into shapes like toucans, jaguars, and other wild figures that make good gifts, alongside tacky options like plastic replicas of Christ the Redeemer.
Good-quality beachwear and Brazilian soccer jerseys are also
popular, though you'll need to choose between cheap imitations at
market stalls and more expensive official merchandise.
Rio is the birthplace of Havaianas (flip flops), so they're
available in any number of brands, styles, and colours. One of the
best things to buy in Rio de Janeiro though, is music, with albums
available of Brazil's distinctive local music. Modern Sound on
Barata Ribeiro has the biggest collection, or for a good selection
of jazz music and books, head to the artsy Livraria da
The gift shop at the Museu do Índio has a selection of pots, woven baskets, and wooden artefacts made by indigenous tribes. Another unique souvenir is the cachaça, or sugar cane brandy, brewed at Petisco da Vila. Try a bottle after watching the production process right in the brewery.
Good-quality local arts and crafts can be found at outdoor weekend markets, the best of which include the Hippie Fair, the Babilônia Hype Fair, and the enormous Feira Nordestina São Cristóvão, which has over 700 stalls. For flowers and food, including fruit, vegetables and cheeses (though you won't be able to bring them home), Praca General Osorio in Ipanema and Rua Domingos Ferreira in Copacabana are also worth a visit.
Most items are reasonably priced, as long as you stay away from the obvious tourist traps around the major hotels. Bartering is acceptable though, and you can usually earn yourself up to a 10 percent discount in shops if you pay cash, though most shops and even some markets will accept major credit cards. Shops tend to stay open Monday to Friday from 9am to 7pm, and shopping centres stay open daily from 10am to 10pm. Sales tax is 18 percent, and there is no tax refund scheme for departing tourists in Brazil.
Become our Rio De Janeiro Travel Expert
We are looking for contributors for our Rio De Janeiro travel guide. If you are a local, a regular traveller to Rio De Janeiro or a travel professional with time to contribute and answer occasional forum questions, please contact us.
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No one will have to ask "Where's the party?" with these king-sized solar swizzle sticks to light the way to your home or backyard. Ten sticks each have 6 clear LED lights inside, which can be set to flash/always on/twinkle. Uses 1 AA rechargeable battery (included). String is approx. 27" l; each stick is 3/4" diam. x 26 3/4" h with 4 1/2" stakes. Available only in multi.
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1051 E Broad St
Falls Church, VA 22044
Driving is something most of us have to do every day. For many it seems like a chore. Koons Falls Church Nissan is here to tell you it doesn't have to be. More than that, we're here to prove it with a revered lineup of new Nissan models and used cars - not to mention expert service, genuine parts and specialized auto repair. That's right; everything you need to transform your daily commute into a joy ride and maintain that sense of satisfaction is right here, under one roof.
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The spokesperson for Jim Koons Automotive Companies is Krystal Koons.


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User Review: Mountain House Scrambled Eggs with Bacon
Price Paid: $5
Arguably the least edible food I've ever tasted. Completely nasty. Cooked this on a backpacking trip for my daughter, while I had the eggs with peppers. I made this for my girl and tasted it, absolutely dreadful.
Wanting an honest opinion from her I brought it to the tent and let her try it...her cry from inside the tent was "oh my god this is DISGUSTING!!". and the arm extended out of the tent with the bowl. it's the artificial bacon flavor that is completely nasty. It got half a star because it might keep you alive if necessary.
The eggs and peppers on the other hand were pretty tasty! But after one bite I made the mistake of reading the nutrition label...which reveals that these products are comprised mainly of cholesterol and salt. While I understand that certain fats and salts are required by backpackers, I am definitely reading labels on all backpacking meals..and many are incredibly non-healthy. Definitely read labels on all Mountain House products, some are very reasonable, others are NOT.


text: youtube [ Woman Gets Chased by Rabbit Stampede [VIDEO] By Tom Morgan 3 weeks ago There is the 'Running of the Bulls', and then there's this...... Read More Category: Animals, SoJO Morning Show, Videos Tags: Japan, Rabbit Stamped, Rabbit Stampede, Rabbits, Woman Gets Chased by Rabbit Stampede Send to a friend! Print this page Share on Facebook Share on Twitter Pin it! Reddit This! Share on Tumblr!


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More students staying in residence halls plus an anticipated enrollment increase mean a new lease on life for the University of Nebraska-Lincoln's Cather Residence Hall.
The university announced Tuesday that it will reopen the residence hall this fall. It had closed the building in May in anticipation of the opening of the new 513-bed University Suites residence hall at 18th and R Streets.
But based on the number of housing contracts received so far, housing officials decided to put the 50-year-old residence hall at 609 N. 17th St. back into service.
Sue Gildersleeve, UNL's director of housing, said more students are returning to on-campus housing. Part of that increase, she said, has to do with the university's new suite-style and apartment-style housing, which tends to be popular with upperclassmen.
"It may be part of the story that we're making some gains on that," she said.
At the same time, university officials are optimistic they'll be able to announce an enrollment increase this fall, said Alan Cerveny, dean of enrollment management.
The coming school year will be the first in an initiative announced by UNL Chancellor Harvey Perlman to increase enrollment to 30,000 students by 2017.
UNL isn't the only college campus in the region watching — or adding to — its space.
The University of Nebraska at Omaha still has about 200 of its 2,100 campus housing spaces available. But officials there expect those beds to be full by the time school starts.
In Iowa, the Board of Regents this spring agreed to allow Iowa State University to lease five off-campus apartment buildings with 503 beds for a year to temporarily boost its capacity, said Pete Englin, director of residence.
Iowa State is expecting its second consecutive year of record enrollment and its seventh year in a row of enrollment growth, officials said. It's also seen an 8.5 percent increase in the number of students returning to live on campus.
UNL officials said they can't yet say how many students they expect, given that enrollment and housing contracts still are in flux. Housing contracts will continue to be accepted through August.
But the numbers were enough to signal the need for more space, they said. In previous years when housing requests have exceeded capacity, students have been assigned temporary quarters in converted lounges in traditional residence halls.
This year, however, the high number of students seeking on-campus housing made that option impractical, Gildersleeve said. And while the lounges aren't a bad solution, re-opening Cather allows the university to assign students to rooms they can use all year and to keep the lounges open for studying, meetings and socializing.
"One of the benefits of living on campus is the opportunity to form community and roommate bonds," she said. "We've found that students in temporary housing are usually reluctant to move out of the community later in the year when a permanent space becomes available."
Plans call for eventually demolishing Cather and neighboring Pound Hall, but no date has been set for either. Cather, which is air-conditioned, was not being mothballed, and no fixtures had been removed. Most furniture is built-in. The university is buying additional beds and hiring some additional staff.
"That's part of the reason it was so easy to bring it back," Gildersleeve said.
Pound remains open and is scheduled to close in May 2014.
University Suites was intended to help replace the lost capacity. A third suite-style hall is slated to open in 2014. The Robert E. Knoll Residential Center opened in 2010.
Room assignments for students who signed contracts after April 1 are being sent this week, and some of those students will be assigned to Cather. Gildersleeve said she expects to have about half of the 13-floor residence hall open again when fall classes begin Aug. 26.


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CLZ Comics - Comic Database
By Collectorz.com
Open iTunes to buy and download apps.
** Catalog your comic collection on your iPad or iPhone **
Auto-download cover art, creators, characters, etc.. Just enter series titles or scan barcodes with your device camera.
* Automatically add comics to your database
Just enter series titles or scan comic barcodes with your device camera. CLZ Comics will automatically download full issue details, including creator and character lists, sollicitation texts / plot descriptions and cover images.
* Catalog your comic collection & wish list
Track the issues you own and the ones on your wish list. Organize and manage detailed issue information like Series, Issue Nr, Publisher, Publication Date, plus personal stuff like Purchase Information, Condition, Rating, Notes and Tags.
* Browse your comic database as an issue list, a cover "wall" or in cover flow mode. View full issue information in the details panel. Group issues in Series or Publisher folders. Search your database with the Quick Search box.
* Free CLZ Cloud storage of your collection data:
Upload your collection data to the CLZ Cloud to have a full backup of your data. Sync your data between devices (e.g. iPhone and iPad) through the CLZ Cloud.
- iOS 5.0 or higher
- for barcode scanning: iPhone 3GS and up, iPad 3 and up, or iPod touch 5th gen and up.
If you are having a problem with CLZ Comics, please contact us for help using the little "?" button inside the app (top right). Please do not use an App Store review to report the problem, because that way we cannot contact you with the solution!
What's New in Version 2.5.2
* Coverflow images not showing up after a direct export over WiFi or USB
Customer Reviews
Pretty good
Very handy indeed! Price was a bit high however it has been worth it thus far. My two complaints are: does not automatically remove comic from wishlist when added after entering a purchase to your collection (you have to manually do this which can get tedious and confusing), and I wish there was a sorting ability for upcoming releases by release date - it already lists the date on the details so I would think it would be easy to make it a sorting parameter.
Don't get me wrong, great app. Open it up every time I walk into the comic shop so I have my list in front of me.
Best App On my iPhone!!
This app has everything I need to compile my entire collection of comics. All you do is scan the barcode find your comic and add it. After it's added you can upload it to the cloud then pull the info to your PC or Mac with the CLZ computer software. The price is a little high but it is easily made up in all the features and perks you get with the app and computer software. Definitely recommend.
This is really cool!!!
It's a little pricey but it has almost no learning curve and you can keep your comic list in a cloud so the info never gets lost! Also it syncs with your other devices and you can log in from any computer to access your list, make changes and print it! From a guy who has thousands of comics (1982-now) this makes keeping track of your comics fun and not seem like work!
- $14.99
- Category: Utilities
- Updated: Feb 11, 2014
- Version: 2.5.2
- Size: 7.0 MB
- Language: English
- Seller: Bitz & Pixelz BV
- © Collectorz.com
Compatibility: Requires iOS 5.0 or later. Compatible with iPhone, iPad, and iPod touch. This app is optimized for iPhone 5.


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Click through for photos from the White House premiere of Lifetime's The Road to Bountiful, the party for the season-four return of IFC's Portlandia and more events for the week of March 10.
Through the Wire
Contributors: Kent Gibbons, Linda Moss.
Finally, an ITV Hit: Tossing Tomatoes
When was the last time you saw a letter to the editor that raved about something great the local operator did for a consumer? One recently caught the eye of a Wire correspondent, published in the Capital Times of Madison, Wisc.
Consumer Jeff Sawyer felt compelled to share his delight over the use of a new set-top delivered game, "Tomato," available on the Moxi Media Center box from his operator, Charter Communications Inc.
The game allows you to launch tomatoes — or your choice of other foodstuffs, including cream pies, strawberries, grapefruit and lemons — at television content on the screen. (We're told the egg option provides an especially satisfying squish upon impact).
"Paris Hilton story on E! Splat … Michael Jackson. Splat. Got him right on the noses," enthused Sawyer in his letter.
Robin Rees, director of corporate communications for Digeo Inc., the Moxi box maker, said Tomato started as an "Easter Egg," one of those little extras computer programmers sneak onto things such as DVDs to give those who know to find and open them a little extra value for their money.
The game proved popular, but also a bit disruptive to Charter, its biggest customer. Subscribers were calling in to ask how to work the game, Rees explained, so Digeo moved the game onto the menu with directions. (Sample: Throw. Splat. Repeat).
Data shows that each week in the Moxi markets, 20% of the deployed boxes are being used to play their games, and a big proportion of those are playing Tomato, Rees said.
"It's proven to be a big hit," even with "jaded press and analysts" who get product demos, Rees said.
As for that Wisconsin consumer, he wrote he's considering finally investing in a wide-screen TV for the next presidential election cycle. We presume he'll be a partisan pelter.
From Calif. To Chicago, Comcast Loses Friends
Now, from the complaining letters department: On our Web site last week (www.multichannel.com), we reported on Comcast Corp.'s problems in Alameda, Calif., where it was accused of switching customers of a municipal utility's high-speed Internet service to Comcast's cable-modem service without their permission; and in Chicago, where it angered customers by moving Sci Fi Channel from analog to digital to make room for Comcast-owned The Golf Channel.
In our stories, a Comcast official in California explained that the Alameda situation was a mistake; while another official in the Midwest said the change was done to bring the Chicago lineup into conformity with other lineups in the region.
That said, other Internet sites were still publishing angry missives about those situations last week. Our staff spotted one on Web site The Straight Dope (www.straightdope.com), citing the Alameda situation and saying Comcast had switched him from the utility ISP to Comcast and that upon calling to complain, the Comcast CSR asked, "Sir, what is your Comcast account number?" That was followed by a little growling emoticon.
And a pal forwarded one from the Chicago Tribune's site: A letter to the TV column on the subject ending with, "Yes, of course they are trying to force people to get digital! And while Comcast may not actually hate us, it's become clear that they inherited from their inept predecessors a fundamental disrespect for the customer. Not only do I hope this move backfires on them big time, I suspect it actually will."
But You Can Please Some By Dropping Most Channels
From anger over a shifted channel to … delight at many dropped channels.
Here's a case study that you probably wouldn't learn about at a CTAM session: A tiny cable system in Missouri dropped its cable networks and actually gained subscribers.
Bill Severn, general manager of NPG Cable Inc.'s Missouri operations, earlier this year purchased a teeny system in Easton, Mo., for $5,000. He bought it after a plea from the town's mayor, since the system's old owner was about to close it down.
"For about two years, I have wanted to take a small cable system and offer a broadcast-only basic plan and high-speed cable modems, and see if there is a business model that works," Severn said during a panel at the National Cable Television Cooperative's recent meeting.
The system had been offering 24 channels for $29. Severn stripped that down to nine-channel broadcast-basic service for $7.95, and launched high-speed data for $39.95 a month. Within 30 days, video subscribers increased, from 35 to 45, and NPG also signed up 15 high-speed customers.
That all added up to $1,150 in incremental cash flow a month at the system.
"We took away everybody's ESPN and Discovery Channel, and launched a basic-only off-air, and customers went up," Severn said. "We didn't lose one of the 35 pre-existing customers. And all we did was mail everybody in town a letter that said, 'We're in town. Here's what we have and here's what it cost.'"
What's the lesson? "You may want to change the tint in your glasses," Severn said. "That ugly little cable system we've all talked about that has 27 channels that cannot compete against DBS — with a few minor changes —might be mean more cash in your pocket and long-term success."
'F.A.T Chance' Sparks Teary Responses
Oxygen's premiere of Mo'Nique's F.A.T. Chance, with its beauty contest for full-figured women, delivered not only plus-sized ratings but a huge response from viewers. Oxygen and The Parkers star Mo'Nique so far have received about 1,000 e-mails about the two-hour special, which aired Aug. 6.
"This thing has hit a gigantic nerve with women across America who feel body image is a constant thought," Oxygen CEO Gerry Laybourne said last week. "The kinds of thank-you notes we're getting, they make you cry."
One woman lauded Oxgyen and Mo'Nique "for taking a step in breaking the cycle of shame." Another viewer wrote, "It was the best show I have ever seen dealing with large women. … I appreciate the way the contestants were treated with dignity and respect. It made me laugh and cry! Being a large woman myself, it really helped me to appreciate myself and others more, whether large or small."
The special garnered some gigantic ratings for Oxygen, as well. It posted a 1.1 household mark, according to Nielsen Media Research, making it Oxygen's highest-rated telecast ever. Over the weekend of its debut, with its replays, the special attracted a total of 3.8 million viewers.
As the hip-hop crowd says, that's phat.


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I would like to record .wav files using android. is there any way to do this...anybody help me... thanks in advance
Take the 2-minute tour
Stack Overflow is a question and answer site for professional and enthusiast programmers. It's 100% free, no registration required.
After a quick google I found out that there is a direct support for wave recording. Most common wave format is PCM. The android.media.AudioRecord supports PCM output. You only need to write this to a file then. After the file you then create you must program your own convertor to wave (or look for an online library for that). If you like an app that is ready to go and record in wave you can download this app: Extra link: |
There are two classes that can record audio, AudioRecord and MediaRecorder.
I also write an application right now, that is recording and showing the frequency spectrogram. So I use AudioRecord class good luck! |


text: Ladies Night is a 10,000 coin jackpot video slot machine game that is available for play at many online casinos that are run on the Microgaming software. This casino game has five gaming reels running on 9 paylines with a host of unique features that have guaranteed its popularity. The game has a Ladies Night out theme, which incorporates clubbing, giving the game a party feel. Players who choose to play this game for free may do so at any of the Microgaming casinos. The real prizes however, are reserved for players with money accounts. These players can make wagers of up to 10 coins per payline, with coin values ranging from $/£/€ 0.01 to $/£/€ 1.00. The regular symbols in this game are Party Girl, Cocktail, Perfume, Purse, and Lipstick along with card faces from Ace to Nine. In addition, the game also has a wild symbol and a scatter symbol, which are the special symbols of Ladies Nite. The wild symbol is the Glitter Ball symbol, which can substitute for all the regular symbols to complete winning combinations. In this game, if there is more than one winning combination in a spin, then only the highest payout is made. The scatter symbol is the Waiter symbol. This symbol triggers the Australian Style Free Spin Bonus. - reviewed by Latest Casino Bonuses, last updated 2012-11-09


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Class Action Litigation Reform – Interview with Dan Pascucci, Member, Mintz Levin
Prosecuting Environmental and Toxic Torts
Is Fracking Safe?
On November 15, 2012, the U.S. Department of Justice announced that BP Exploration and Production Inc. (BP) has agreed to plead guilty to a 14-count criminal information and pay a record $4 billion in criminal fines and...more
One headline in today's Daily Environment Report stated that "EPA Considers PCB Regulatory Reform Amid State Regulator Criticism of Program." Even my advanced sarcasm skills failed me on reading this. I'll therefore settle...more
As of this writing, the April 20, 2010, BP Deepwater Horizon explosion and subsequent oil spill in the Gulf of Mexico appears to be contained and well sealed. After several failed attempts to cap the 5,000-foot deep well, BP...more
Find a Toxic Torts Author »


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- Crewe Alexandra News
- Fixtures
- Results
- News Archive
- Information
- League Table
- Statistics
- Squad
- League Two News
- Forum
Silkmen complete midfielder swoop
Daniel joined Crewe in the summer of 2007 after impressing for Eastwood Town in the Northern Premier League and has made 12 starts for the Railwaymen this term. Alexander said: "I wanted to sign him last season so I am delighted he has agreed to join us at the Moss Rose this time. "Whilst he is predominantly a left sided midfielder, he has also played up front. These are two areas in which we have struggled in recently. "Its clear we need to freshen things up and change things around a little."
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03 February 2012
The Bermudian reinsurer has announced Q4 results, including net income of $27.3m, a steep drop from 2010's figures.
Read more: Validus Q4 Financial Results Ed Noonan
Validus has seen its income for the fourth quarter of 2011 plummet, according to its latest financial results.The Bermudian group's net income dropped almost 75% to $27.3m from a figure of $102.7m in the final three months of 2010.
Net income for the year was similarly impacted, with Validus reporting a total of $21.3m for the twelve months period representing...
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More copies of this ISBNBorn on a Blue Day: Inside the Extraordinary Mind of an Autistic Savantby Daniel Tammet
Synopses & ReviewsPublisher Comments:A journey into one of the most fascinating minds alive today—guided by the owner himself.
Bestselling author Daniel Tammet (Thinking in Numbers) is virtually unique among people who have severe autistic disorders in that he is capable of living a fully independent life and able to explain what is happening inside his head. He sees numbers as shapes, colors, and textures, and he can perform extraordinary calculations in his head. He can learn to speak new languages fluently, from scratch, in a week. In 2004, he memorized and recited more than 22,000 digits of pi, setting a record. He has savant syndrome, an extremely rare condition that gives him the most unimaginable mental powers, much like those portrayed by Dustin Hoffman in the film Rain Man. Fascinating and inspiring, Born on a Blue Day explores what it's like to be special and gives us an insight into what makes us all human—our minds. Synopsis:The first-ever memoir by an autistic savant, a man who can speak ten languages, who sees numbers with color and texture, who broke a record by memorizing over 22,000 digits of pi—and can write about it all with inspiring and heartbreaking simplicity and clarity.
Synopsis:One of the worlds only 50 living autistic savants is the first to tell his compelling and inspiring life story, and explain how his incredible mind works. While Tammets brain has amazed scientists for years, readers will be moved by this remarkable mans story.
About the AuthorDaniel Tammet is a writer, linguist, and educator. A 2007 poll of 4,000 Britons named him as one of the world's "100 living geniuses." His last book, the New York Times bestseller Born on a Blue Day: Inside the Extraordinary Mind of an Autistic Savant, has been translated into 18 languages. He lives in Avignon, France.
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- Visit Interlaken in the Swiss Alps on a day trip from Zurich
- Enjoy scenic drives and mountain views
- Travel to the town of Grindelwald, known as Glacier Village
- Take an optional cable car ride up Mt. First during the summer months
- Have free time to explore in both Interlaken and Grindelwald
What You Can Expect
The guided coach tour takes you on scenic routes to Interlaken at the foot of the snow-covered Alps of the Bernese Oberland. After some time at leisure in Interlaken journey to the well-known holiday resort of Grindelwald, which is nick-named the 'Glacier Village'. You will have enough time to explore this region on your own.
An optional cable car ride (operates only late May - late October) to the sunny terrace of Mt. First at 2168m / 7113 ft is recommended - for a breathtaking panorama of the Bernese Alps. In the late afternoon meet your coach and guide for the return journey to Zurich.
Customer Reviews
September 2013
I went on the Top of Europe tour guided by Kid. It was fabulous. The tour guide made the tour very lively and I had an excellent time.
July 2013


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