text:
Definition of arid in English:
Line breaks: aridPronunciation: /ˈarɪd
- 1(Of land or a climate) having little or no rain; too dry or barren to support vegetation: the arid plains north of Cape TownMore example sentences
- However, from Karadi to Dandi, the land is arid and the vegetation scrubby.
- The arid climate makes the desert the best outdoor setting to keep planes free of corrosion.
- The arid land of this autonomous republic supports a nomadic lifestyle.
dry, dried up, waterless, as dry as a bone, moistureless, parched, scorched, baked, thirsty; dehydrated, desiccated; barren, desert, waste, desolate; infertile, non-fertile, unfruitful, unproductive, uncultivatable, sterile
- 2Lacking in interest, excitement, or meaning: his arid years in suburbiaMore example sentences
- Human stories are more interesting than an arid study of theology.
- Yoga classes without this element seem to me arid and dull.
dreary, dull, drab, dry, sterile, banal, colourless, monochrome, unstimulating, uninspiring, flat, boring, uninteresting, monotonous, lifeless, tedious, vapid, jejune, soul-destroying
- More example sentences
- There was a world cooling - eight hypotheses exist to explain it! - with intense aridity that created Australia's sub-zones such as south-western and north-western Australia.
- By the way, Darwin was a naturalist and most would take his comments about Australia's limited prospects as relating to soil quality and aridity, and the subsequently smaller potential population.
- More than anything I was struck by how incredibly green and lush everything looked after the dryness of the Spanish countryside. I have not been to Spain before, and I was quite taken aback by the aridity of it all.
- More example sentences
- I am struck by how many serious intellectuals we have writing at the moment, not aridly intellectual, but certainly with a spiritual dimension - the spirituality of the everyday.
- Parris also seems to approve of the seemingly sophisticated but actually aridly semantic implied argument behind the phrase.
- The writer continues to investigate the ideas of care and love, but he also speculates aridly on the nature of literary creativity.
- More example sentences
- Book releases, art exhibitions, theatre camps and more, holding out the promise of being a haven for creativity in these times of aridness.
- The bouncy tempo and scale-based riff are the sparsest elements on the whole album and after 40 minutes of extraordinarily dense arrangements the aridness is a nice change of pace.
- The lands of the Southwest, in their aridness, showed him concretely the underlying fragility of the land community, and the interconnectedness of its members.
Pronunciation: /əˈrɪdɪti/
mid 17th century: from French aride or Latin aridus, from arere 'be dry or parched'.
More definitions of arid
Definition of arid in:- The US English dictionary
- The English Synonyms
- The US English Synonyms


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Jeff ... you people are the greatest site on the web for every magic need I have ... I love you!!!!Read More ->
I just want you all at MJM Magic to know that you guys are the greatest! Superb service and great prices. I will be ordering from you guys from now...Read More ->

subset: commoncrawl


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BeerAdvocate on your phone?! True story. Try the beta now.
Tickets for American Craft Beer Fest are on sale now! (May 30 & 31 in Boston, MA)
No picture uploaded. Have one? Upload it now. Taps: - / Bottles: - Cask: / Beer-to-Go: N |
Ratings: 9 | Reviews: 9
Reviews by lhaqq:
3.65/5 rDev +4.9%
vibe: 3 | quality: 4 | service: 3 | selection: 4 | food: 4 | $
At the risk of advertising the good prices, and thus increasing the people that go and causing them to jack up prices, this is a pretty reasonably priced place. The had probably thirty or so beers on tap. The menu advertised that "after five beers are $2.50." I thought it was a way to get people drunk and to buy a lot of beer--i.e. buy five beers and the rest are $2.50. Of course, it it ended up being that it is after 5pm that all beers are that price, so I will definitely be back. The food is pretty good as well. Atmosphere isn't anything too great--just a regular grill type place.
12-28-2008 06:47:53 | More by lhaqq
More User Reviews:
3.43/5 rDev -1.4%
vibe: 4 | quality: 3.5 | service: 3.5 | selection: 3 | food: 3.5 | $$
I used to go here a lot about 10 years ago and I went here again for the first time in a while relatively recently. Pleasant bar area right on Telegraph with a great patio out back. They still have the hand drawn chalk beer portraits and a nice open feeling. This used to be kinda a center of beer culture, but these days seems more like a college bar with slightly dumbed down taps. Still some okay local stuff, but nothing really special stood out. Many places have eclipsed this place in that regard. Good, solid pub food, and quite a few healthy options, but overall the food seems to have slipped a bit. Decent and pleasant place, but nothing work seeking out unless you are on Telegraph.
10-29-2008 04:02:41 | More by Georgiabeer
3.23/5 rDev -7.2%
vibe: 3.5 | quality: 3.5 | service: 3 | selection: 3.5 | food: 2 | $
Raleigh's is a serviceable pub on the Telegraph strip in Berkeley.
The atmosphere is somewhat kitchy, mostly varsity. They do have decent beer on tap...quite a few California microbrews along with some macro imports like Newcastle & Guinness, by the glass or the pitcher. If you have a friend who drinks hard alcohol, strongly urge them NOT to order the agave wine margaritas...they are disgusting!
The servers are generally friendly enough, but not always very attentive. This may be due to age, as most look to be college-age or younger.
Main downside to Raleigh's is the food. It's affordable, which is good, but not usually edible. The kind of thing which tastes okay after a few bites but goes bad quickly, only to be finished if you are really drunk. Plus I've heard my fair share of horror stories over the years regarding a rat problem here (endemic to most of Telegraph, me thinks).
Anyway, a good stop if visiting the Telegprah area for a pint or two...and make sure you go when Cal doesn't have a game going, otherwise it will be impossible to get a beer, let alone a seat. For a great beer experience, however, I recommend Jupiter or Albatross instead.
02-22-2008 00:29:44 | More by Natural510
2.83/5 rDev -18.7%
vibe: 3 | quality: 2.5 | service: 3 | selection: 2.5 | food: 4 | $$
not a bad place but there are soooo much better in the Bay Area. I stop here when I shop Telegraph road but I would not go out of my way for a beer here.
The atmosphere is nice wooden bench tables and bar are appealing and the crowd seems friendly.
The quality of the beer selection is ok at best they are in a great area and would have access to many great local beers but they keep the same ok ones on tap here. I usually drink the Moose Drool when I am here.
Service is always friendly although not beer experts they try.
Selection as stated could be so much better but they are always crowded so why rock the boat.
Food is always good standard Cal pub type menu and always fresh tasting and well prepared.
So overall is it just ok great for a stop off if you are in the area but I would not go out of my way to try this place.
12-31-2007 20:02:14 | More by jp11801
3.23/5 rDev -7.2%
vibe: 4 | quality: 3.5 | service: 2 | selection: 3.5 | food: 4 | $$$
Located on Telegraph Avenue in Berkeley, Raleigh's is out of the way, yet easily accessible to the general Berkeley public and students alike.
The atmosphere is nice with the wooden-and-brick architecture. The wooden furniture as well as a spacious patio outside makes this place very nice to eat and drink.
The quality of the food and drink is also quite good. I've gone there a couple of times and there is never anything wrong with what I've ordered (except for once, when my friend's cracked beer mug broke and spilled beer all over us).
The service on quieter nights is OK, since the place is quite large, and there never seems to be enough servers. The servers are nice, but it oftentimes takes a while to get food or drink.
The selection of drinks are pretty good, since they have about 20-or-so beers along with a selection of wines and a few cocktails (although one wouldn't go there for anything other than the beer).
The food is also quite good, since the place isn't focused solely on drinks. It does take some waiting for them to make it, but the food really is quite decent.
Overall, expect to pay 8-10 dollars per meal and roughly 11 dollars per pitcher, which is pretty average here in Berkeley. Overall, not a bad place. Very good because of their selection.
10-10-2007 22:25:02 | More by Boneheadmx
3.44/5 rDev -1.1%
vibe: 3 | quality: 3.5 | service: 4 | selection: 3 | $
Raleighs is a slightly above average bar in a good location. It offers 19 taps (2 of which are nitro I think) and 10 bottles but all of those are BMC. The taps are a nice mixture of CA micros including Bear Republic, Speak Easy, Sierra Nevada, Anderson Valley, and Stone. Service is friendly and available. The atmosphere is cantina with roosters. Well drawn chalk boards display symbolic pictures of their beer. The stereo played Michael Jacksons Off the Wall while I was there. Pints were $3.25and there happened to be a special on El Oso pitchers that day $3 each I had a good time.
05-12-2006 03:10:46 | More by DaPeculierDane
3.1/5 rDev -10.9%
vibe: 3 | quality: 3.5 | service: 4 | selection: 2 | food: 2.5 | $$
This was my number one bar during my college years. Kip's was too Greek, Blake's was too expensive, and Bear's lair wasn't too big yet. Yes, I do have a Raleigh's Tshirt. Tough to do these days because of the micros and the changing taps.
A college hangout. My senior year they had a deal where it was 9.50 a pitcher for the good beer. Needless to say I downed countless pitchers there. Ambience is ok, pool table, shuffleboard and darts. Backyard beer garden is one of a kind in berkeley. Too bad its so cold up there, which is why I moved back to so cal after I graduated. Absolutely packed after cal football and basketball games. Staff is helpful and personable. Bear's Lair is more popular now because of their specials. I suggest going down to shattuck if you want a more unique brew. Try Jupiter's.
12-15-2005 21:06:17 | More by drewmprs
4.28/5 rDev +23%
vibe: 4 | quality: 4.5 | service: 4 | selection: 4.5 | food: 4 | $$
This place was a regular for me while I was an undergrad at UC Berkeley.
Most of the regulars are Cal students, but there is a nice mix early in the evening before the college crowd gets out.
They used to have only micros and craft brews but due to market pressures they have started to offer some macros on tap.
They have also lowered the prices on many of their micros on tap because of macro pressure.
Their food is the standard pub grub, burgers all on fresh baked buns from a next door bakery. I recommend the avocado, bacon, swiss burger, totally a California thing.
I went there when they had a frequent buyers card where if you drank 30+ beer's on the list you got a free T-shirt but since macros have entered the picture they don't have it anymore.
Still one of the best beer bars in Berkeley.
07-07-2005 08:30:03 | More by Bang34
4.15/5 rDev +19.3%
vibe: 4 | quality: 4 | service: 4 | selection: 5 | food: 3
Great collage bar. Lots of young people, and lots of great beer.
It's close to Peoples' Park so if you drink too much there is a place to crash.
They have 20 + beers on tap and more by bottle. A traditional long bar.
Their food is average pub grub. Burgers, and what not. Nothing to write home about, but it doesn't detract from the wooded back patio and the great beers and friendly service.
It's a great place to go late in the week when they have extended hours.
Be aware that it is a collage bar and can get very crowded with young folk in the evenings.
If that is not your thing go during the day or on a non sporting event day and you can enjoy the food and beer outside in very peaceful suroundings.
09-12-2004 05:18:00 | More by Tang07
Raleigh's in Berkeley, CA
out of 100
based on 9 ratings.


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Petition calls for North Bennington school revoteBy Patrick McArdle
STAFF WRITER | November 14,2012NORTH BENNINGTON After a vote to close the North Bennington Graded School passed in October, a petition might force a second revote. That would make three votes total, on replacing the public school with an independent school.
Gail Mauricette, school clerk for North Bennington, said a petition calling for a revote had been submitted to her Tuesday. State law requires a petition calling for a revote to have the signatures of 5 percent of registered voters.
For a vote in the North Bennington school district, which includes the village and parts of the town of Shaftsbury, Mauricette said a successful petition would have needed about 80 signatures. The petition submitted Tuesday had 130 signatures. However, Mauricette said she had not yet had a chance to check all the signatures and make sure the names match the voter checklist.
Joyce Scarey, who turned in the petitions Tuesday, said her concerns included turning the public school over to a board whose members are not elected by local residents and who are not required to have open meetings. She said those who signed the petition have similar concerns.
All the signatures that are on that page, theyre citizens (who) believe that North Bennington Graded School should remain as it has for over 100 years, a public school, she said.
Scarey said she supports the school and pointed out that her husband, John, was on the North Bennington School Board for 13 years.
In March, voters overwhelmingly approved ballot questions on Town Meeting Day that would have allowed the School Board in North Bennington, called the North Bennington Prudential Committee, to close the school and lease the building and its equipment to the board of trustees for an independent school called the Village School of North Bennington.
Independent schools must be approved by the Vermont Board of Education which tabled the request in May.
Over the summer, the School Board decided to continue operation of the public school. Because the vote in March included language about closing the public school at the end of the 2011-12 school year, School Board members said they believed they would need a new vote before moving forward with their plans.
The state School Board also said they would need a second vote before approving the independent school to be sure it had voter support.
The October vote had two questions, both of which needed to pass in order for the public school to close. The first question, asking if the voters would give the School Board permission to close the school, passed with 52.3 percent of the voters supporting the question, 294-268.
If the petition filed Tuesday is found to be valid, the School Board will have to host another election within 60 days, according to state law.
Eva Sutton, co-chairwoman of the independent schools board of trustees, said in an email that she expected the prudential committee will set the date soon for the next vote.
We will work, for the third time, toward a positive vote of the North Bennington school district so that we can open the Village School of North Bennington in the fall of 2013 for children locally, Sutton said.
Supporters of the independent school, like Sutton, say that it will keep North Benningtons school located in the community and not subject to the possibility of forced closure or consolidation which they are concerned the state may require especially if enrollment declines and education expenses increase.
firstname.lastname@example.com IN Southern VermontBENNINGTON A Saratoga Springs, N.Y. Full StoryBENNINGTON A Sleepy Hollow, N.Y. Full Story -
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text:
A fantastic game and apart from a lack post-story content, the high point of the series.
Emono wrote this review on .
Sound: 9.6/10
Gameplay: 10/10
Longevity: 8.8/10
Overall: 9.45/10
I first got Ruby in May 2004, after spending 4 months paying it off myself, being the fan of the original games that I was, I was extremely excited at the game that awaited me. I turned it on and never looked back.
The overworld in Ruby is, whilst simplistic, close to perfect. Hoenn is a bright and colourful region and is showcased fantastically throughout the game. The pokemon's sprites themselves are simple too, but they're all fantastic, the only thing that could've made the sprites more impressive is if they were animated (which happened in Emerald anyway).
The music in the game is the best that has ever been in the pokemon games. There are many memorable tracks and fantastic battle music too.
The gameplay is standard Pokemon fare, in other words, RPG perfection. It plays incredibly well and it is surprising how it feels fresh every time.
However, the games weak point is it's longevity. Sure, there is plenty to do during the 50-hour story, but afterwards, there is next to nothing, which is a sad anti-climax.
To sum it up, apart from the post-game lack of content, Pokemon Ruby is possibly the best main series game yet.


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I know I've said this a million times, but I really miss the shaved-head Britney. She was so much more lovable and ridiculous. But shocking news - she said she regrets the TV show she filmed with her ex-hubby, Kevin Federline. [Celebuzz]
Remember Britney and Kevin: Chaotic, the much-derided reality TV seriesabout Britney Spears and Kevin Federline's marriage? Well, if you do, Spears definitely wants you to forget it.
"I would never do something like that again." she tells The Telegraph. "Actually, that was really bad," she continues about the documentary. "That was probably the worst thing I've done in my career."
"The increased scrutiny does make me a little harder on myself these days," Spears adds. "There are more expectations of me now, not just in terms of what I do, but also in terms of who I am."
And what does the singer think of her widely-panned theatrical debut, Crossroads?
"I like Crossroads!" Spears tells the publication, laughing. "F**k you!"


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Today in History for Year 1948 (Part 4)
◀ May June Jul ▶ | ||||||
Sun | Mon | Tue | Wed | Thu | Fri | Sat |
1 | 2 | 3 | 4 | 5 | ||
6 | 7 | 8 | 9 | 10 | 11 | 12 |
13 | 14 | 15 | 16 | 17 | 18 | 19 |
20 | 21 | 22 | 23 | 24 | 25 | 26 |
27 | 28 | 29 | 30 | |||
◀ 1947 1948 1949 ▶ |
Months in Year 1948: January February March April May June July August September October November December
Historical Events
Events 301 - 400 of 491
Aug 6th - Bob Mathias, US, wins decathlon at London Olympics
Aug 6th - Dreesgovernment (KVP/Social Democratics/CHU/Liberal) forms
Aug 6th - Fanny Blankers-Koen (Neth) is 1st women to win 3 golds at Olympics
Aug 7th - 1st Dutch government of Beel resigns
Aug 7th - Delfo Cabrera wins 11th Olympic marathon (2:34:51.6)
Aug 8th - "Hold It!" opens at National Theater NYC for 46 performances
Aug 10th - ABC enters network TV at 7 PM (WJZ, NY)
Aug 10th - Allen Funt's "Candid Camera" TV debut on ABC
Aug 10th - Bradman scores 133* Aust v Lancashire, 216 mins, 17 fours
Aug 10th - WABC TV channel 7 in New York, NY (ABC) begins broadcasting
Aug 11th - Summer Olympics opens in London
Aug 12th - Cleveland Indians get 29 hits in a 9 inning game
Aug 12th - Court of justice sentences Gen Fr Christiansen to 12 years
Aug 13th - Satchel Paige at 42, pitches his 1st major league complete game
Aug 14th - 14th Olympic games close at London, Great Britain
Aug 14th - Bradman's last Test Cricket innings
Aug 14th - England all out for 52 v Australia at Cricket Oval
Aug 15th - 3rd US Women's Open Golf Championship won by Babe Didrikson-Zaharias
Aug 15th - Republic of Korea (South Korea) proclaimed (National Day)
Aug 16th - Arabs blow up Latrun pumping station in Jerusalem
Aug 16th - Israeli pound becomes legal tender
Aug 17th - Alger Hiss denies ever being a Communist agent
Aug 17th - Phillies commit 8 errors in a game
Aug 17th - Tom Henrich hits his then record tying 4th grand slam of season
Aug 20th - 15th NFL Chicago All-Star Game: Chi Cards 28, All-Stars 0 (101,220)
Aug 20th - US expels Soviet Consul General in New York, Jacob Lomakin
Aug 21st - Indians 47-inning scoreless streak broken by White Sox Aaron Robinson
Aug 23rd - Earl Bernadotte asks aid for fugitives to Palestine
Aug 23rd - World Council of Churches formed by 147 churches from 44 countries
Aug 25th - Bradman scores 150 in 212 minutes in his last innings at Lord's
Aug 27th - 102°F highest temperature ever recorded in Cleveland in August
Aug 31st - Queen Wilhelmina celebrates 50th jubilee
Sep 1st - Bradman scores 143 Aust v South of England, 17 fours 1 six
Sep 1st - Communist form North China People's Republic
Sep 1st - UN's World Health Organization forms
Sep 3rd - W Gomulka deposed as general secretary of Polish Worker's party
Sep 4th - "Angel in the Wings" closes at Coronet Theater NYC after 308 perfs
Sep 4th - Queen Wilhelmina abdicates Dutch throne
Sep 5th - In France, Robert Schuman becomes President of the Council while being Foreign minister, As such, he is the negotiator of the major treaties of the end of World War II.
Sep 6th - "Mr Strauss Goes to Boston" opens at Century Theater NYC for 12 perfs
Sep 6th - 37th Davis Cup: USA beats Australia in New York (5-0)
Sep 6th - Juliana becomes queen of Netherlands
Sep 7th - 1st use of synthetic rubber in asphaltic concrete, Akron Oh
Sep 8th - British De Havilland 08-fighter flies faster than sound
Sep 9th - "Hilarities (of 1949)" opens at Adelphi Theater NYC for 14 perfs
Sep 9th - Bkln Dodger Rex Barney no-hits NY Giants, 2-0
Sep 9th - People's Democratic Republic of Korea proclaimed
Sep 10th - Bijz Criminal division sentences war criminal Jacob Folks to life
Sep 10th - Bradman scores 153 in his last 1st-class cricket innings in England
Sep 12th - Invasion of the State of Hyderabad by the Indian Army on the day after the Pakistani leader Jinnah's death.
Sep 13th - Margaret Chase Smith (R-Me) elected senator, 1st woman to serve in both houses of Congress
38th US President Gerald Ford
Sep 14th - Gerald Ford upsets Rep Bartel J Jonkman in Mich 5th Dist Rep primary
Sep 14th - Ground breaking ceremony for UN world headquarters
Sep 14th - Milton Berle starts his TV career on Texaco Star Theater
Sep 15th - "Small Wonder" opens at Coronet Theater NYC for 134 performances
Sep 15th - F-86 Sabre sets world aircraft speech record of 1080 kph
Sep 15th - WHN-AM in NY City changes call letters to WMGM
Sep 16th - "Heaven on Earth" opens at Century Theater NYC for 12 performances
Sep 16th - "Mr Strauss Goes to Boston" closes at Century NYC after 12 perfs
Sep 17th - KCOP TV channel 13 in Los Angeles/Hollywood, CA (IND) begins
Sep 17th - WLS TV channel 7 in Chicago, IL (ABC) begins broadcasting
Sep 18th - "Hilarities (of 1949)" closes at Adelphi Theater NYC after 14 perfs
Sep 18th - Communist Madiun-uprising in Dutch Indies (Muso/Sjarifudin)
Sep 18th - Ralph J Bunche confirmed as acting UN mediator in Palestine
Sep 19th - 62nd US Women's Tennis: M Osborne duPont beats A L Brough (4-6 6-4 15-13)
Sep 19th - 68th US Men's Tennis: "Pancho" Gonzales beats E Sturgess (6-2 6-3 14-12)
Sep 19th - Richard A Gonzales wins US Tennis Open
Sep 20th - "Magdalena" opens at Ziegfeld Theater NYC for 48 performances
Sep 20th - Mexican Baseball league disbanded
Sep 21st - "Texaco Star Theater" with Milton Berle premieres on NBC-TV
Sep 23rd - Braves clinch NL pennant
Sep 24th - Mildred Gillars (Axis Sally) pleads innocent in Wash DC
Sep 24th - Yanks, Boston & Cleveland are tied for 1st place in AL (91-56)
Sep 24th - The Honda Motor Company is founded.
Sep 25th - "Heaven on Earth" closes at Century Theater NYC after 12 performances
Sep 26th - Boston Braves win 1st NL championship since 1914
Sep 27th - "Carib Song" opens at Adelphi Theater NYC for 36 performances
Sep 28th - WBAP-TV, (NBC affiliate) Fort Worth Texas, begins broadcasting
Sep 29th - Laurence Olivier's "Hamlet" opens at Park Avenue Cinema
Sep 29th - WBAP (now KXAS) TV channel 5 in Fort Worth-Dallas, TX (NBC) begins
Sep 29th - WSB TV channel 2 in Atlanta, GA (ABC) begins broadcasting
Oct 1st - California Supreme Court voids state statue banning interracial marriages
Oct 1st - Radio Denmark begins transmitting
Oct 2nd - "Finian's Rainbow" closes at 46th St Theater NYC after 725 perfs
Oct 3rd - Columbia U reports discovery of uranium in Belgian Congo
Oct 3rd - NFL becomes 1st sport televised as sport of week
Oct 4th - Indians beat Red Sox, 8-0, in 1st AL playoff game
Oct 4th - World Council of Churches forms under W Fisherman It Hooft)
Oct 5th - The 1948 Ashgabat earthquake kills 100,000.
Oct 6th - "Polonaise" opens at Alvin Theater NYC for 113 performances
Oct 6th - KHJ TV channel 9 in Los Angeles, CA (IND) begins broadcasting
Oct 9th - WXYZ TV channel 7 in Detroit, MI (ABC) begins broadcasting
Oct 10th - Then record 86,288 see game 5 of World Series in Cleveland
Oct 11th - "Love Life" opens at 46th St Theater NYC for 252 performances
Oct 11th - "Where's Chartev?" opens at St James Theater NYC for 792 performances
Oct 11th - Cleve Indians beat Boston Braves, 4 games to 2 in 45th World Series
Oct 12th - Casey Stengel takes over as Yankee manager
Oct 14th - Batavia lt-governor-general Of Mook dismissed
Oct 14th - Large scale fighting between Israel & Egypt
Oct 15th - China's Red army occupies Chinchov
Famous Birthdays
Birthdays 301 - 400 of 806
Apr 30th - Wayne Kramer, guitarist (MC5, Dangerous Madness)
May 1st - James Wise, US soul singer (Archie Bell & the Drells)
May 2nd - Larry Gatlin, Seminole Tx, country singer (Gatlin Bros-Broken Lady)
May 3rd - Chris Mulkey, American actor
May 4th - Billy O'Donnell, harness racer driver of year (1984)
May 4th - Hurley Haywood, American race car driver, and three-time winner of the 24 Hours of Le Mans
May 4th - George Tupou V, Tonga, King of Tonga (2006-2012), (d. 2012)
May 5th - Bill Ward, Birmingham England, heavy metal drummer (Black Sabbath)
May 5th - Frank Esier-Smith, rocker
May 6th - Richard Cox, NYC, actor (Mark-Executive Suite)
May 7th - Peter Wingfield, Wales, rocker/actor (Methos-Highlander)
May 8th - John Reid, MP
May 8th - Maurizio Nichetti, actor (Icicle Thief, Volcano)
May 8th - Stephen Stohn, Canadian television producer (Degrassi)
May 9th - John Drayton Mahaffey, Kerrville TX, PGA golfer (1978 PGA Champ)
May 9th - Hans Georg Bock, German mathematician
May 9th - Calvin Murphy, American basketball player
May 10th - Christopher Gent, CEO (Vodafone Group)
May 11th - Alfred Matt, Austria, slalom (Olympic-bronze-1968)
May 11th - Nirj Deva, Sri Lankan-British politician
May 11th - Shigeru Izumiya, Japanese folk musician
May 12th - Lindsay Ann Crouse, NYC, actress (Slapshot, Iceman, Places in Heart)
May 12th - Steve Winwood, England, rock bassist (A Higher Love)
May 14th - Bob Woolmer, cricketer (England batsman mid-70's)
May 14th - Dave LaRoche, baseball pitcher (NY Yankees)
May 14th - Walter Olkewicz, Bayonne NJ, actor (Last Resort, Wizards & Warriors)
May 15th - Brian Eno, Woodbridge England, rock keyboardist/singer (On Land)
May 16th - Katia Dandoulaki, Greek actress
May 18th - Felix MH Troch, Flemish actor/director (Gekkenbriefje)
May 18th - Joe Bonsall, Phila, country singer (Oak Ridge Boys-Elvira)
May 19th - Grace Jones, [Mendoza], Spanishtown Jamacia, singer/actress (Vamp)
May 19th - Jean-Pierre Haignere, France, cosmonaut (Soyuz TM-17)
May 19th - Tom Scott, LA, saxophonist/bandleader (Pat Sajak Show)
May 20th - Dave Thomas, St Catherines Ontario, comedian (SCTV, Grace Under Fire)
May 20th - John Amiel, director (Queen of Hearts, Tune in Tomorrow)
May 20th - John R McKernan Jr, (Rep-R-ME, 1983-86/Gov-Maine)
May 20th - Samuel Gejdenson, (Rep-D-Connecticut, 1981- )
May 21st - Carol Potter, actress (Beverly Hills 90210)
May 21st - Leo Sayer, [Gerard], England, singer (When I Need Love)
May 22nd - Richard Baker, (Rep-R-Louisiana)
May 23rd - Reggie Cleveland, baseball player
May 25th - Sgt. Slaughter, American professional wrestler
May 25th - Klaus Meine, German musician (Scorpions)
May 26th - Geoff Greenidge, cricketer (no relation to Gordon, WI opener 1972-74)
May 26th - Stevie Nicks, American rocker and songwriter (Fleetwood Mac, Bella Donna)
May 27th - Aleksandr Aleksandrovich Volkov, cosmonaut (Soyuz TM-8, T-14, TM-7)
May 27th - Anna E "Annelies" Balhan, Dutch revue-artist/actress (Sweet Chairty)
May 27th - Pete Sears, bassist (Jefferson Starship)
May 28th - Bob Shearer, Melbourne VIC, Australasia golfer
May 28th - Ray Laidlaw, British rock drummer (Jack the Lad)
May 29th - Anthony Geary, Coalville Utah, actor (Luke/Bill-General Hospital)
May 29th - Linda Esther Gray, opera singer
May 29th - Michael Berkley, composer/broadcaster
May 29th - Nick Mancuso, Italian-Canadian actor
May 30th - Michael Piller, American screenwriter (d. 2005)
May 31st - Duncan L Hunter, (Rep-R-CA, 1981- )
May 31st - John Bonham, Redditch England, drummer (Led Zeppelin-Stairway to Heaven)
May 31st - Lynda Bellingham, actress (Sweeney, Scarlet Tunic)
Jun 1st - Tom Sneva, US auto racer (Indianapolis 500-1983)
Jun 1st - Tomáš Halík, Czech priest and public intellectual
Jun 2nd - Albert Innaurato, Phila, playwright/director (Age in Soho)
Jun 2nd - Jerry Mathers, Sioux City Iowa, actor (Beaver-Leave It To Beaver)
Jun 4th - Bob Champion, horse trainer/jockey
Jun 4th - Rosemary Joyce, model/actress (Daphne Draper-Search For Tomorrow)
Jun 4th - Sandra Post, LPGA golfer
Jun 5th - Frank Estersmith, Australia, rocker (Air Supply)
Jun 6th - Richard Sinclair, English musician (Caravan)
Jun 9th - Jim Bailey, NCAA punter (most punts in season-101, Va Milt Academy)
Jun 9th - Nathaniel Rosen, Altadena Ca, cellist (Tchaikovsky-gold-1978)
Jun 9th - Gudrun Schyman, Swedish politician
Jun 11th - Anthony Nelson, British Sec of Treasury
Jun 11th - Skip Alan, [Alan Skipper], drummer (Them, Pretty Things)
Jun 11th - Stephen Schnetzer, Boston Mass, actor (Cass Winthrop-Another World)
Jun 12th - Barry Bailey, Doraville Ga, rocker (Atlanta Rhythm Section)
Jun 12th - Norbert Phillip, cricketer (WI pace bowler late 70s)
Jun 12th - Hans Binder, Austrian racing driver
Jun 13th - Garnet Bailey, Canadian ice hockey player and executive (d. 2001)
Jun 13th - Joe Roth, American executive, producer and film director
Jun 15th - Champ Summers, baseball player
Jun 16th - Ron LeFlore, American baseball player
Jun 17th - David Concepcion, Venezuela, all star shortstop (Cincinnati Reds)
Jun 18th - Éva Marton, Hungarian operatic soprano
Jun 19th - Nick Drake, rocker (Back to Fruit Tree)
Jun 19th - Phylicia Rashad, Houston, Texas, American actress and singer (The Cosby Show, One Life to Live)
Jun 19th - Dervin Gordon, rocker
Jun 20th - Joey Molland, rocker
Jun 20th - Nigel Morris, rocker (Isotope)
Jun 20th - Ludwig Scotty, President of Nauru
Jun 21st - Joey Malland, Liverpool, rock guitarist (Badfinger-Come & Get It)
Jun 21st - Ian McEwan, English writer
Jun 21st - Lionel Rose, Australian boxer
Jun 21st - Andrzej Sapkowski, Polish writer
Jun 22nd - "Pistol" Pete Maravich, NBA star (Atlanta Hawks)
Jun 22nd - Nolan Clarke, cricketer (Barbados bat 1970-77, later Holland stalwart)
Jun 22nd - Sue Roberts, LPGA golfer
Jun 22nd - Todd Rundgren, Upper Darby PA, singer/guitarist (Hello it's Me)
Jun 23rd - Clarence Thomas, Savannah Ga, 108th US Supreme Court Justice (1991- )
Jun 23rd - Myles Goodwyn, Montreal, rock guitarist/vocalist (April Wine)
Jun 23rd - Nigel Osborne, composer
Jun 23rd - Darhyl S. Ramsey, American author
Famous Weddings
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Famous Deaths
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Burt Bacharach
Burt Bacharach
Tribute to Burt Bacharach and Hal David
Original Release Date: February 19, 2002
Track Listing
1. This Guy's in Love With You
2. Raindrops Keep Falling on My Head [From Butch Cassidy and The Sundance
3. A House Is Not a Home
4. Wishin' and Hopin'
5. (They Long to Be) Close to You
6. Don't Make Me Over
7. Alfie [From Alfie]
8. What's New Pussycat?
9. 24 Hours from Tulsa
10. I Just Have to Breathe
11. Wives and Lovers
12. Do You Know the Way to San Jose?
13. Make It Easy on Yourself
14. One Less Bell to Answer
15. The Look of Love
16. Reach Out for Me
17. I Just Don't Know What to Do With Myself
18. Walk on By
19. Say a Little Prayer
20. Do You Know the Way to San Jose?
21. Anyone Who Had a Heart
22. What the World Needs Now Is Love
Dionne Warwick: Performer
Paul Carrack: Performer
Petula Clark: Performer
Elvis Costello: Performer
Edwin Starr: Performer
Brian Kennedy: Performer
Burt Bacharach: Performer
Linda Lewis: Performer
Kenny Lynch: Performer
Brian Conley: Performer
Elian: Cover Design


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Definition: asmon: A system resource monitor dockapp for Afterstep and WindowMaker Asmon is a wharfable/dockable application for that displays meters detailing CPU, memory, swap, and X mem usage. Also included the exact numbers for load average, mem, swap, and X. Developed to use very little CPU time itself.
Source: Debian 3.0r0 APT / Linux Dictionary V 0.16
Author: Binh Nguyen linuxfilesystem(at)yahoo(dot)com(dot)au


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On May 1, an OST single for SBS drama Brilliant Legacy (찬란한 유산) was released. Three tracks in total, including a song called 사랑에 미쳐서 sung by Jisun.
Tuesday, May 12, 2009
1 comment:
thanx for the info. i was looking for
the songs XD - Sunday, June 28, 2009
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Update: Be sure to check out our first post about this from 2007!
This 2007 profile of Hubert Duprat's work with caddis fly larvae is a tiny, entomological miracle. The larvae build their cocoons with whatever material is at hand; Duprat forces them to build with gold and precious gems, making spectacular bio-organic jewelry.
Duprat, who was born in 1957, began working with caddis fly larvae in the early 1980s. An avid naturalist since childhood, he was aware of the caddis fly in its role as a favored bait for trout fishermen, but his idea for the project depicted here began, he has said, after observing prospectors panning for gold in the Ariège river in southwestern France. After collecting the larvae from their normal environments, he relocates them to his studio where he gently removes their own natural cases and then places them in aquaria that he fills with alternative materials from which they can begin to recreate their protective sheaths. He began with only gold spangles but has since also added the kinds of semi-precious and precious stones (including turquoise, opals, lapis lazuli and coral, as well as pearls, rubies, sapphires, and diamonds) seen here. The insects do not always incorporate all the available materials into their case designs, and certain larvae, Duprat notes, seem to have better facility with some materials than with others. Additionally, cases built by one insect and then discarded when it evolves into its fly state are sometimes recovered by other larvae, who may repurpose it by adding to or altering its size and form.
Artist Project / Trichopterae (via Neil Gaiman)
(Photos: Jean-Luc Fournier)
I write books. My latest is a YA science fiction novel called Homeland (it's the sequel to Little Brother). More books: Rapture of the Nerds (a novel, with Charlie Stross); With a Little Help (short stories); and The Great Big Beautiful Tomorrow (novella and nonfic). I speak all over the place and I tweet and tumble, too.
MORE: Delightful Creatures • fashion.art • jewelry
More at Boing Boing
18 Responses to "Caddis fly larvae coaxed into building cocoons out of precious metals and gems"
Antinous / Moderator says:
Well, at least they're not hellgrammites.
Jake0748 says:
I always feel proud when I can respond to one of Antious' comments without having to resort to google or wikipedia. Alas, this was not one of those times.
Felton / Moderator says:
Jeez, was this thing genetically engineered from a Clive Barker doodle?
Antinous / Moderator says:
I grew up catching those things to use as bait. Those and leeches.
Jake0748 says:
So yeah, now you can have your gold jewelry made by enslaved bugs. No further need to use whining human workers who might want a living wage n stuff.
PhasmaFelis says:
Are you trolling? You're trolling, aren't you. Try harder.
ImmutableMichael says:
I was just about to say "it was funny but doesn't look like trolling to me". But then I thought, "maybe PhasmaFelis is trolling and i'll look stupid for responding"… Trolling/meta trolling.
Now I'm just confused. Mine's a double. Thanks.
Gulliver says:
Do not try to feed the troll — that's impossible. Instead, only try to realize the truth: there is no troll. Then you'll see that it is not the troll that trolls, it is only yourself.
PhasmaFelis says:
I didn't intend to troll, but maybe I got too snarky and trolled by mistake. Maybe I trolled myself. Shit, that's heavy. I think I need to lie down.
(Srs tho my forum vice is overreacting/being way snarkier than is actually justified, not trolling. I think. Hope.)
siloxane says:
Big deal. I can get larvae to produce cocoons out of pure silk!
noah django says:
>bio-organic jewelry
I had to go over it a few times, but I think these are just objéts d'art. there's no mention in the link of them being jewelery, it just says stuff like "sculptural." these things are cool.
planettom says:
I don't know the answer to this, I'm just asking the question.
Do the flies develop normally after doing this? Do they grow into happy adult flies?
Or is doing this, the touch of death, from Mr. Goldfinger (bwah bwah, bwah!).
That is, is this just an artistic variation of pulling the wings off flies or standing above an anthill with a magnifying glass?
Beanolini says:
No reason why they shouldn't develop normally after this, they make their cases from far less savoury (and less inert) materials in the wild. It does rather depend on the goodwill of M. Duprat as to whether they actually end up as 'happy adult flies'.
He must have been doing this for an awful long time, I remember seeing a magazine article about it in the mid 90s.
Birdseed says:
I misread this as "caddish fly larvae", which made me ponder what prompted such etymological invectives. Was it the rather showy flaunting of their riches?


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Picture This: Nick Poohachoff
Posted Dec. 31, 2010
Alli Sports has a new feature called "Picture This", and our hard workin' Vans Am Pooch is the man. Nick "Pooch" Poohachoff stepped behind the camera this time to give us a look into his world. What did we learn? 1. His fridge is empty. 2. He rolls with Benjamins in his backpack. 3. His friends pack heat! This and other visual insights can be found at www.allisports.com.
Trick Tip: Switch BS 900 With Eric Willett
Posted Dec. 29, 2010
From SNOWBOARDER Magazine:SNOWBOARDER is bringing you a series of how-to snowboard videos to help fill up that bag of tricks, and help you learn how to ride that snowboard a little better.Big things are happening for Eric Willett. After impressive finishes in last year's contest circuit, Quiksilver just brought him on their team. It might be a bit early in the season to start throwing switch backside 900's, but maybe you can listen to what Eric ...
SUP BRO?: Eric Willett Full Part
Posted Dec. 27, 2010
From Snowboarder Magazine: Sup Bro? Bra, shaka, far out, radical, tubular, totally, double cork, bitchin, cowabunga, dude, epic, sick, EXTREME, chyeah, dank, fo' sho, gnarly, righteous. You get the point. Eric Willett, Chris Willett, Zak Shelhamer's parts from the Colorado based snowboard film… "Sup Bro?". If you can put all of those words above into one sentence…. you are the man.
In Your Face With Andreas Wiig
Posted Dec. 24, 2010
Winter Dew Tour darling and all-around bad ass Torstein Horgmo has a new website, www.torstein.net, filled with all kinds of cool videos, photos and more. Just released is a game of "In Your Face" with Vans Team Rider Andreas Wiig. Watch as Torstein and Andreas go head-to-head in Breckenridge, challenging each other to perform tricks until somebody loses and gets sprayed in the face. Who's it going to be? Only one to find out...
Second "RT To Win" Twitter Contest Winner
Posted Dec. 22, 2010
Congratulations to @AshleyyNicole_ for being the second winner of the "RT To Win" twitter contest. For retweeting one of our @vanssnow tweets with the #VansSnow hashtag, @AshleyyNicole_ scored a brand new pair of Vans Snowboard Boots! Nice job Ashley, we hope you get to use them a lot this season, and judging by the snowfall amounts this year, it looks like you'll have plenty of chances. Have a great winter, and thanks to everyone who entered the contest. Remember ...
Cheryl Maas Takes Third Place At Winter Dew Tour
Posted Dec. 20, 2010
The first stop of the Winter Dew Tour is a wrap, and Vans had two riders in the slopestyle competition looking for that first big win of the season. Eric Willett and Cheryl Maas were in the finals on Sunday and despite the near blizzard-like conditions, rode like the winter warriors they are. As AlliSports.com puts it, "For a moment, it seemed like Breckenridge local Eric Willet would take the event title after throwing the run of his life ...
Vans Team At Breckenridge Dew Tour
Posted Dec. 18, 2010
Eric Willett and Nick Pooch. Photo: Dave Doomey.Our man on the scene Dave Doomey checked in with an update and some photos from the Winter Dew Tour in Breckenridge, CO this weekend. Vans Team Riders Andreas Wiig, Hana Beaman, Eric Willett and Vans Am Nick Poohachoff are all in town taking part in the action. Here's what he had to say: "Eric and Andreas were the two competitors today. Andreas was riding well but did not make the ...
Pooch Cameo in "Dropping In With Chas"
Posted Dec. 16, 2010
Vans Am Nick Poohachoff is a busy beaver these days. On top of all his footage out of NZ this summer, Nick scored a cameo in Episode 2 of the web series, "Dropping in with Chas", which looks to document Chas Guldemond's 2010/2011 season. This second episode follows Chas as he gets his feet under him through the beginning of his season in Summit Country, Colorado. Guest appearances by Luke Mitrani, Scotty Lago, Torstein Horgmo, Tim Humphries, Ian ...
Hana Beaman On Snowboarder Magazine's Guestbook
Posted Dec. 13, 2010
Hana Beaman checked in with Snowboarder Magazine recently for another edition of their "Guestbook". This is where pros check in with the mag and answer semi-ridiculous questions that usually have nothing to do with snowboarding. It's a chance for the readers to get up close and personal with the riders and delve a little deeper into their personality. In this edition, Hana finally solves the mystery to such questions as, "What's the key to a good wedgie?".
First "RT To Win" Contest Winner
Posted Dec. 10, 2010
Congratulations to @dcsk8terboy for being the first winner of the "RT To Win" twitter contest. Just for retweeting some of our @vanssnow tweets with the #VansSnow hashtag, dcsk8terboy grabbed himself a brand new pair of Vans Snowboard Boots! Hopefully, now he will change his twitter name to @vanssk8terboy... Or maybe even @vanssnowboy if he gets enough days on the hill with his new boots. Good luck dude and thanks to everyone who entered the contest. Remember, we'll be doing ...
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Tam's Green Juice
Jo Elwin
There's been a lot of talk about juices and smoothies in the Bite kitchen of late, with many of us adding them in to our diet for one reason or another.
Our photographer Tam prefers juices and has become the very proud owner of an Oscar juicer. To make the delicious green juice pictured, click here.
I prefer smoothies and have been making them in a Vitamix which is an incredibly powerful machine that completely grinds up pips and skins and other parts of fruits and vegetables you would normally have to cut out, so you're getting even more of the nutrients and the fibre.
You can use Tam's recipe in the Vitamix or a blender to create a green smoothie, like this one, above.
When I quizzed Nadia Lim about the de rigueur green smoothie she said, "about half of us don't meet our recommended fruit and vegetable intake every day. Having a freshly-made juice or smoothie is an easy way to up our intake of fruit and vegetables, and thus important vitamins and antioxidants, in something that's refreshing and delicious.''
You'll need a juicer to make juices but smoothies are easily made in your blender. "In fact", says Nadia, "by using a blender to blend up all the ingredients, you're keeping the fibre in the drink which is an added bonus. You can add other things into your smoothies to boost the nutrition, such as oats to make it a 'thickie' which will increase the fibre; yoghurt or milk to add calcium; nuts like cashew nuts or almonds, or avocado to boost the healthy fat content (avocados make amazing smoothies).
"Though juices are great, they should not completely replace eating whole fruit and vegetables, as juicing often removes the fibre. The best way to enjoy juices and smoothies is to have one or two a day and meet the rest of your fruit and vegetable intake by eating whole fruits and veges."


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Select an edition for more focused local news coverage when you visit mlive.
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A water main break at Adams and Gladstone Dr. SE in Grand Rapids, Mich. Wednesday, January 23, 2013 created a giant sink hole and caused flooding for residents.


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Found November 24, 2012 on
Holdout Sports:
An Ohio State Buckeye fan stormed the field and videobombed an ESPN interview with linebacker Zach Boren after Saturday's win over Michigan.
The OSU fan first popped in front of the camera, then stepping back and peeking between Boren and his interviewer. To top it off, the Buckeye fan overshadowed both of them by making the 'OHIO' letters with his arms and destroying any chance for the interview to be taken seriously by anyone.
GIF via SBNation. H/T Sports Grid.
Visit us at http://holdoutsports.com and Follow @HoldoutSports
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Original Story:
Tressel given very warm reception
He may be the reason Ohio State is banned from the postseason this year, but Buckeyes fans gave former coach Jim Tressel an extremely warm reception on Saturday.
Urban Meyer rallies fans with profanity
Ohio State coach Urban Meyer spoke at a tailgate and pumped up the fans in attendance with some profanity at the end of his speech.
Today The Ohio State Buckeyes Completed A Perfect 12-0 Season Proving They Don't Give A Damn About The Whole State Of Michigan
The Ohio State Buckeyes Cannot Let The Michigan Wolverines Halt Their March To Perfection
OSU, Michigan players get into it
A group of Michigan and Ohio State players got into it with each other during warmups before their big rivalry game. See video here.
BCS & AP Top 25 projections week 14: Notre Dame one win away from BCS Championship, Ohio State on AP top three bubble
Eleven reasons the Buckeyes are 11-0
Report: Ohio State's John Simon out against Michigan
Ohio State stays perfect to win ''The Game''
PERFECTION!! Buckeyes Close Out 12-0 Season
Discover Fan Loyalty Poll: Ohio State Buckeyes Could Have Had Much More To Be Thankful For Today
Michigan and Ohio State players jostle before The Game
Bank Blog: Quick Thoughts Defense
College Football Forum Discussions
2 replies,
January 14, 2014
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text:
How to Make a Natural Household Fly Spray
Edited by Brielle Jade, Krystle, Eric, Lois Wade and 9 others
Got flies? You don't need to run to the store and get a noxious chemical spray this time. It is possible to make your own fly spray at home. This one is based on the U.S. Forest Service bug spray recipe.
Body spray:
- 1 cup water
- 1 cup Avon Skin So Soft Bath Oil
- 2 cups vinegar
- 1 tbs. Eucalyptus oil (found in health food stores)
Optional: few tablespoons of citronella oil.
Room spray:
- 18 oz (2 1/4 cups) white vinegar
- 2 Tbsp dish washing soap
Method 1 of 2: Body Spray
1In a non-reactive bowl (ceramic or glass), mix all of the ingredients together.Ad
2Pour into a clean spray bottle.
3Shake the spray bottle well to mix the ingredients.
4Label. Date and label the bottle with each of the ingredients plus directions for use.
5Use by spraying on body. It is probably wise to do a skin patch test to ascertain any allergic reactions.
Method 2 of 2: Room Spray
- This recipe is suitable for humans, horses, and dogs.
- Store in a place out of reach of children and pets.
- This mixture will not keep indefinitely; throw out if not used up with a season.
- Do not use on cats.
Things You'll Need
- Bowl (ceramic or glass)
- Wooden spoon for mixing
- Funnel for pouring
- Spray bottle
- Labels and markers
Sources and Citations
- Body spray adapted from US government resource cited at Moniteau Saddle Club, Flyspray recipes.
Article Info
Featured Article
Categories: Featured Articles | Fly Control
Recent edits by: Katniss.Stardoll, Chris Hadley, June
In other languages:
Deutsch: Wie man natürliches Haushalts Fliegenspray herstellt, Español: Cómo hacer un espray natural contra moscas
Thanks to all authors for creating a page that has been read 121,266 times.


text:
The DMS (Digital Media Station) range sits at the top end of Hi-Grade's selection of Media Center PCs. It's designed to be the heart of your multimedia world, storing photos, music, recording television and playing hi-def Blu-ray movies directly on to your big-screen television. With dedicated Blu-ray players such as the Samsung BDP-1000 costing around the £800 mark, the £1,600 price doesn't seem entirely unreasonable either. You can buy the Hi-Grade DMS Extreme Xtc2_02 direct from the Hi-Grade site.
The DMS Extreme Xtc2_02 looks like a DVD player that's been fed a strict diet of steroids and lard. Its horizontally oriented chassis makes it seem ideal for replacing your existing VHS or DVD player, but bear in mind that at 430 by 410 by 160mm it's about twice as tall as ordinary AV equipment -- it may not fit under your TV.
The top and sides of the PC have a shiny black metal finish, while the front has a matte brushed-metal effect. The front panel is subtly concaved, which helps to reduce the boxy overall look.
It's hard not to notice the vacuum fluorescent display (VDD) installed in the top left of the front panel. This, by default, displays the name of the PC as well as the current time of day, but can also show what's happening inside Windows Media Center. The only drawback is that it has been connected to a rear-facing parallel port to receive the data -- which means there's a discreet cable running from the inside to the outside of the machine.
At the front are a couple of flip-down panels that hide the system's input-output ports. The panel to the far right hides the Blu-ray drive, while the middle panel hides a memory card reader, which supports a range of popular formats. That's a handy addition to a Media Center PC, but we can't fathom why there's only one USB port at the front -- that's truly lame.
Things are relatively straightforward at the back of the PC, apart from a Wi-Fi aerial that protrudes by about an inch when upright or by four inches when fully extended. There's also two separate D-Sub video ports (one on the graphics card and another on the motherboard IO port). This could conceivably baffle the hell out of novice users.
There's an element of skill in building a dedicated media PC, but although Hi-Grade has definitely taken steps in the right direction, there are drawbacks in its choice of components for the DMS Extreme Xtc2_02. (Read this article on what you need to do to build the perfect Media Center PC).
The Xtc2_02 uses a motherboard with a mobile chipset, ie one designed for laptops. This is a good choice, as laptops generally use less power and make less noise than desktop PCs -- benefits that translate well to a Media Center PC.
As a result, Hi-Grade has had to install laptop-specific memory -- in this case a pair of PC2-4300 1GB DIMMs -- and a mid-range laptop processor, the Intel Core 2 Duo T5600, which runs at 2GHz. The downside is that you can't add any existing desktop PC memory you might have lying around, as it won't fit.
The upside is that, becasue the processor is designed for laptops, it runs cooler than normal desktop chips, which, in theory, means Hi-Grade can use a quiet fan. Unfortunately, Hi-grade has used a standard Intel-branded heatsink and fan, which is still noisy despite the cooler chip.


text:
It looks like the fine folks over at Latin0-Review have got one of the biggest scoops of the year. According to their site, they know who the five members of the Justice League for their big screen adaptation will be.
It seems there is also the possibility of one or two cameo appearances by a few other "Leaguers". The most likely candidates for those two spots are Martian Manhunter and Aquaman with Martian Manhunter being the mostly likely to get a cameo. Off in left field, but still with a shot to appear is Hawkman.
Having only five members does make sense, since this will pretty much be an origin story not only for the league, but most likely for some of the members. Add that to the fact that their will most likely be some sort of romantic entanglement, the plot, and then throw in Darkseid's plans and you have a movie on the verge of breaking 3 hours. If any other members were included it would be tough to fit them all in.
Well one fact is out for the movie. Now wait patiently for many more facts to come out soon!
Source: Latino-Review


text:
The automobiles in the lead may be moving a little slow, but cut them some slack, because they are more than 70 years old.
The Northeast Texas Region Antique Automobile Club of America, otherwise known as the Greenville Antique Car Club, plans to roll out rain or shine Sunday for the "Pre War Tour" across northern Hunt County, according to organizer Glen Jones.
"The lead cars are all from before World War II," Jones said. "The newer cars are going to be on the tail end."
Even though there is a chance of rain in the forecast through at least early Sunday afternoon, Jones said the tour is expected to proceed as scheduled, with a start from the parking lot of the Hunt County Criminal Justice Center, 2801 Stuart Street, at 2 p.m. Sunday.
Jones expects up to 30 entries to proceed north out of downtown Greenville to the Vittitoe Gin on FM 1566 East. From there the tour will head to Commerce, for lunch at Braum's, before returning to Greenville at around 4 p.m. Sunday for two blasts from the past.
The autos will stop at Crawford Smith, 2210 Lee Street, the third oldest business in continuous operation in Hunt County, where they will be on display and where City Council member Dan Perkins is to offer a brief presentation on the city's history.
From there the tour will proceed to Barnhardt's Steel Machine and Welding Shop, 2000 Jordan Street, the county's second oldest business in continuous operation, before wrapping up with dinner at Jungle Burger, 5420 Interstate Highway 30.
Jones said the procession will not be in any hurry and likely will be moving at no more than 40 miles per hour. David Gish Jr. is expected to drive his classic Pierce Arrow, while the tour will also have two or three "T Models" also in the pack.
Anyone needing additional information about tour can call Jones at 903-268-4800.
Top News
Rolling out of the past
- Top News
- BREAKING: Greenville QuickTrip store opening Thursday morning
About halfway to new paths to schools
Students attending four local elementary schools will have an easier walk to campus by the start of the fall semester.
Suspect in Caddo Mills murder released on bond
The bond for a suspect charged with murder in connection with a February 14 shooting death in Caddo Mills was cut in half Monday.
Trial set next month in 2011 two-county chase
A Caddo Mills man has trial scheduled next month on multiple indictments, filed in connection with a chase between Greenville and Terrell three years ago, which ended with the defendant being shot by law enforcement.
'Desperately seeking lifeguards'
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Police taking aim at gun safety
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Custody hearing today for seized dogs, cats
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Council to accept two buildings at airport
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Morning, Anniephans!
And bye-bye to Hersh Cosmetics, too. Patsy knows nothing about running a company.
And will we ever find out what happened to her brother?
Here's the link to Annie 2004 . -
It's fairly obvious… he saw no way out of his dilemma and chose to end the pain. His thinking was in a downward spiral.
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Luis has worked with WFP since 2011 and has 4 years experience in the area of Monitoring and Evaluation. Previously he was a Peace Corps Volunteer in Nicaragua (2007-2009). He is originally from Peru.


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Wednesday, November 30th, 2011
Photo by Nick Wenning
Marion Local's Justin Rutschilling, 52, has progressed from playing junior varsity football last season to earning first team All-Midwest Athletic Conference honors on both offense and defense this year. Rutschilling has played a key role in the Flyers' run to Saturday's Division VI state championship game against New Washington Buckeye Central.
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US 8067593 B2 Abstract The invention relates to an improved process for preparing aminocrotonylamino-substituted quinazoline derivatives of general formula (I)
wherein the groups Ra, Rb, Rc and Rd have the meanings given in the claims, as well as sulphonyl derivatives of formula and the use thereof as synthesis components for preparing quinazolines of formula (I). The quinazoline derivatives of formula (I) are inhibitors of signal transduction mediated by tyrosinekinases and by the Epidermal Growth Factor-Receptor (EGF-R) and are therefore particularly suitable for the treatment of tumoral diseases. Claims(4) 1. A compound of the formula
Ra denotes a benzyl, 1-phenylethyl or 3-chloro-4-fluorophenyl group and
R3 denotes a C1-4-alkyl group wherein the hydrogen atoms may be wholly or partly replaced by fluorine atoms, or
a phenyl group optionally substituted by one to three substituents selected from C1-3-alkyl groups, halogen atoms, cyano or nitro groups, wherein the substituents may be identical or different.
2. A compound of formula (XIII) according to
3. A compound of formula (XIII) according to
4. A compound of formula (XIII) according to
(1) 4-(3-chloro-4-fluoro-phenylamino)-7-(4-methyl-phenylsulphonyl-)-6-nitro-quinazoline,
(2) 4-(3-chloro-4-fluoro-phenylamino)-7-(4-bromo-phenylsulphonyl)-6-nitro-quinazoline,
(3) 4-(3-chloro-4-fluoro-phenylamino)-7-(phenylsulphonyl)-6-nitro-quinazoline,
(4) 4-(3-chloro-4-fluoro-phenylamino)-7-(4-nitro-phenylsulphonyl)-6-nitro-quinazoline,
(5) 4-(3-chloro-4-fluoro-phenylamino)-7-(methylsulphonyl)-6-nitro-quinazoline,
(6) 4-(3-chloro-4-fluoro-phenylamino)-7-(trifluoromethylsulphonyl)-6-nitro-quinazoline,
(7) 4-(3-chloro-4-fluoro-phenylamino)-7-(nonafluorobutylsulphonyl)-6-nitro-quinazoline,
(8) 4-(3-chloro-4-fluoro-phenylamino)-7-(2,2,2-trifluoroethanesulphonyl)-6-nitro-quinazoline
(9) 4-(benzylamino)-7-(4-methyl-phenylsulphonyl-)-6-nitro-quinazoline,
(10) 4-(benzylamino)-7-(4-bromo-phenylsulphonyl)-6-nitro-quinazoline,
(11) 4-(benzylamino)-7-(phenylsulphonyl)-6-nitro-quinazoline,
(12) 4-(benzylamino)-7-(4-nitro-phenylsulphonyl)-6-nitro-quinazoline,
(13) 4-(benzylamino)-7-(methylsulphonyl)-6-nitro-quinazoline,
(14) 4-(benzylamino)-7-(trifluoromethylsulphonyl)-6-nitro-quinazoline,
(15) 4-(benzylamino)-7-(nonafluorobutylsulphonyl)-6-nitro-quinazoline,
(16) 4-(benzylamino)-7-(2,2,2-trifluoroethanesulphonyl)-6-nitro-quinazoline,
(17) 4-(1-phenylethylamino)-7-(4-methyl-phenylsulphonyl-)-6-nitro-quinazoline,
(18) 4-(1-phenylethylamino)-7-(4-bromo-phenylsulphonyl)-6-nitro-quinazoline,
(19) 4-(1-phenylethylamino)-7-(phenylsulphonyl)-6-nitro-quinazoline,
(20) 4-(1-phenylethylamino)-7-(4-nitro-phenylsulphonyl)-6-nitro-quinazoline,
(21) 4-(1-phenylethylamino)-7-(methylsulphonyl)-6-nitro-quinazoline,
(22) 4-(1-phenylethylamino)-7-(trifluoromethylsulphonyl)-6-nitro-quinazoline,
(23) 4-(1-phenylethylamino)-7-(nonafluorobutylsulphonyl)-6-nitro-quinazoline and
(24) 4-(1-phenylethylamino)-7-(2,2,2-trifluoroethanesulphonyl)-6-nitro-quinazoline.
Description The invention relates to a process for preparing aminocrotonylamino-substituted quinazoline derivatives of general formula (I) Quinazoline derivatives of general formula (I) are known from WO 02/50043 and WO 04/074263, which describe compounds with valuable pharmacological properties, including in particular an inhibitory effect on signal transduction mediated by tyrosinekinases and an inhibitory effect on signal transduction mediated by Epidermal Growth Factor-Receptor (EGF-R). Therefore, compounds of this type are suitable for the treatment of diseases, particularly for the treatment of tumoral diseases, diseases of the lungs and airways and diseases of the gastro-intestinal tract and the bile ducts and gall bladder. WO 2002/50043 discloses a method of production in which aminocrotonylamino-substituted quinazolines (I) are prepared in a one-pot reaction from the corresponding aniline component (II), bromocrotonic acid, oxalyl chloride and a secondary amine (see Diagram 1). Diagram 1:
The process is not well suited to technical use on an industrial scale, as the yields obtained are at most 50% and as a rule laborious purification by column chromatography is needed. Moreover the educt bromocrotonic acid is not commercially available in large amounts and the corresponding methyl bromocrotonate is only available with a purity of about 80%. WO 2005/037824 describes an alternative process for preparing aminocrotonylamino-substituted quinazoline derivatives of general formula (I) by Wittig-Horner-Emmons reaction of dialkyl-phosphonoacetamido-substituted quinazolines (III) with a 2-aminoacetaldehyde (IV) (Diagram 2), while instead of the aldehyde (IV) it is possible to use the corresponding hydrate or an acetal (e.g. the diethylacetal corresponding to (IV)), from which the aldehyde is liberated (beforehand or in situ). Diagram 2:
The educts of formula III may be obtained according to WO 2005/037824 as follows: Diagram 3:
Both in the prior art described above and within the scope of the invention described hereinafter, the groups Ra, Rb, Rc, Rd, R1 and R2 have the following meanings: Ra denotes a benzyl, 1-phenylethyl or 3-chloro-4-fluorophenyl group, Rb denotes a methyl, ethyl, isopropyl, cyclopropyl, 2-methoxyethyl, tetrahydrofuran-3-yl, tetrahydrofuran-2-yl-methyl, tetrahydrofuran-3-yl-methyl, tetrahydropyran-4-yl or tetrahydropyran-4-yl-methyl group, Rc denotes a methyl, ethyl or 2-methoxyethyl group or Rb and Rc together with the nitrogen atom to which these groups are bound denote a morpholino or homomorpholino group optionally substituted by one or two C1-3-alkyl groups, Rd denotes a cyclopropylmethyl, cyclobutyl, cyclopentyl, tetrahydrofuran-3-yl, tetrahydrofuran-2-yl-methyl, tetrahydrofuran-3-yl-methyl, tetrahydropyran-4-yl or tetrahydropyran-4-yl-methyl group, and R1 and R2 each independently of one another denote a C1-4-alkyl group, for example each denote an ethyl group. By a homomorpholino group is meant the next highest ring-homologue of the morpholino group, namely the group of formula
Starting from commercially obtainable 4-chloro-anthranilic acid (V), reacting with formamidine acetate (step a) produces the quinazolinone (VI), which is then nitrated using sulphuric acid and concentrated nitric acid (step b). The desired regioisomer (VII) is then chlorinated using thionyl chloride in acetonitrile (step c) and the chlorination product (IX) is reacted in situ with the corresponding amine Ra�NH2 (step d). The compound of formula (X) thus obtained is reacted by base-catalysed nucleophilic substitution with Rd�OH to form the compound (XI) (step e), which is in turn converted by hydrogenation into the corresponding aminoquinazoline (XII) (step f). The aminoquinazoline (XII) is then converted by reaction with a di-(C1-4-alkyl)-phosphonoacetic acid, e.g. with diethylphosphonoacetic acid, in suitable solvents such as tetrahydrofuran (THF), dimethylformamide (DMF) or ethyl acetate, after corresponding activation, for example with 1,1-carbonyldiimidazole, 1,1-carbonylditriazole or propanephosphonic anhydride, into the dialkyl-phosphonoacetamido-substituted quinazoline (III) needed for the Wittig-Horner-Emmons reaction. The process described in WO 2005/037824 also has a number of serious disadvantages for technical use. For example, the use of thionyl chloride in Step (c) is problematic for safety reasons. The cyclic or heterocyclic alcohols needed to introduce the group Rd in an excess of about 2 equivalents (eq) are starting materials which are difficult to obtain or expensive, and phase transfer catalysis, for example using 18-crown-6, is also needed to react them according to step (e) in Diagram 3 on an industrial scale. The reaction product has to be purified by recrystallisation to eliminate the phase transfer catalyst. The hydrogenation of step (f) is carried out with the addition of acetic acid, if the educt contains a chlorine atom, so as to prevent the formation of dechlorinated by-products which are difficult to strip out. The addition of acetic acid causes traces of the nickel needed as catalyst to be dissolved, and this is then entrained into the final step and gives rise to a heavy metal problem which is unacceptable for pharmaceutical use. Moreover, the throughput of individual partial reactions is in need of improvement; for example the throughput in step (e) according to Diagram 3 is only 1/60 (1 kg of starting material require a reactor volume of 60 l). In the light of the disadvantages of the known production method as described above, the problem of the present invention is to provide an improved method, suitable for synthesis on an industrial scale, which permits the safe preparation of aminocrotonylamino-substituted quinazoline derivatives (I) using easily obtainable starting materials of high purity and at a lower technical cost. The problem stated above is solved according to the invention by the following process for preparing a compound of general formula
In another aspect the invention relates to the sulphonyl derivatives of formula
For example R3 in formula (XIII) may denote the p-toluenesulphonyl, p-bromo-benzenesulphonyl, phenyl, p-nitro-benzenesulphonyl, methylsulphonyl, trifluoromethylsulphonyl, nonafluorobutylsulphonyl or 2,2,2-trifluoroethanesulphonyl group. The following are mentioned as particularly preferred compounds of formula (XIII):
The educts used in the process according to the invention and not described in more detail are either known from the literature or may be prepared from precursors known from the literature by simple analogous methods. For example, the sodium hydrogen sulphite adduct of formula (XIV) may be obtained from the corresponding acetal by liberating the corresponding aldehyde in hydrochloric acid solution and subsequent precipitation by the addition of NaHSO3 solution. The diethylacetal may be prepared from the corresponding aldehyde by conventional methods. Specifically, the invention described in embodiment A has the following partial aspects B, C and D:
The reaction (a) of 7-chloro-6-nitro-3H-quinazolin-4-one (VII) with a primary amine of formula (XV) for preparing a compound of formula (X) is carried out in a suitable solvent, for example in acetonitrile, dioxane, THF, or mixtures thereof, e.g. in a mixture of acetonitrile, dioxane and in the presence of 1-2 equivalents POCl3, at a temperature of 50 to 80� C. The conversion (b) of a compound of formula (X) into the sulphonyl derivative of formula (XIII) is carried out in a suitable solvent, for example in acetonitrile, dioxane, THF, DMF, dimethylacetamide (DMA), N-methylpyrrolidone (NMP) or mixtures thereof, e.g. in a mixture of DMF and NMP by the addition of 1 to 2 equivalents of a corresponding sulphinic acid salt, for example the sodium salt of benzenesulphinic acid, at a temperature between 50� C. and the boiling temperature of the solvent used, preferably at a temperature between 80 and 100� C. The conversion (c) of the sulphonyl derivative of formula (XIII) into a compound of formula (XI) is carried out in a suitable solvent, for example in acetonitrile, dioxane, THF, DMF, DMA, diglyme, tert-butanol or mixtures thereof, by the addition of 1 to 1.5 equivalents of an alcohol of formula Rd�OH (XVI) and subsequent batchwise addition of 2 to 4 equivalents of a strong base, for example powdered NaOH, KOH or LiOH, or potassium-tert.-butoxide, sodium-tert.-butoxide, lithium-tert.-butoxide, potassium-tert.-amylate, sodium-tert.-amylate or lithium-tert.-amylate as a solid or by dropwise addition of a solution of these bases in tert. butanol, THF or DMF, at a temperature between 0 and 100� C., preferably between 10 and 50� C., initially choosing a low temperature and raising the temperature after the addition of the base to complete the reaction. The reduction (d) of a compound of formula (XI) to the amino derivative of formula (XII) is preferably carried out by catalytic hydrogenation with hydrogen in the presence of a catalyst such as Raney nickel, palladium/charcoal or platinum in a solvent such as methanol, ethanol, ethyl acetate, DMF, DMA, NMP, DMF/acetone or DMF/methanol, optionally with the addition of an acid such as acetic acid or an acid salt at temperatures between 0 and 100� C., for example at temperatures between 0 and 80� C., but preferably at a temperature between 20 and 50� C., and under a hydrogen pressure of 1 to 10 bar, for example 1 to 7 bar, but preferably at a pressure of from 3 to 5 bar. The conversion (e) of the amino derivative of formula (XII) into the phosphonic ester of formula (III) is carried out by reacting with 1.0-2.0 equivalents of a di-(C1-4-alkyl)-phosphonoacetic acid, preferably with diethylphosphonoacetic acid, in a suitable solvent such as THF, DMF, toluene, ethyl acetate, methyl-tert.-butylether (MTBE) or mixtures thereof, e.g. in MTBE/THF, after corresponding activation at temperatures between 0� C. and 100� C. The activation may be carried out using any of the current methods of amide linking, i.e. for example with 1,1-carbonyldiimidazole, 1,1-carbonylditriazole, DCC (N,N-dicyclohexylcarbodiimide), EDC (N′-(dimethylaminopropyl)-N-ethylcarbodiimide), TBTU O-(benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate, thiazolidine-2-thione, or by conversion into the corresponding acid chloride, possibly using thionyl chloride or phosphorus oxychloride. Optionally the activation is carried out using organic bases such as triethylamine or pyridine, while DMAP (dimethylaminopyridine) may additionally be added. The reaction (f) of the phosphonic ester of formula (III) with the hydrogen sulphite adduct of formula (XIV) is carried out in a suitable solvent such as methanol, ethanol, THF, DMF, toluene, ethyl acetate and acetonitrile or mixtures thereof or in a binary or ternary mixture with water, preferably in ethanol or ethanol/water, with the addition of a suitable base, e.g. sodium carbonate, lithium hydroxide, sodium hydroxide or potassium hydroxide, optionally with the addition of a stabilising salt such as lithium chloride, at a temperature of 0� C.-50� C., using 1-2 equivalents, preferably 1.2-1.6, e.g. 1.4 equivalents of the hydrogen sulphite adducts in aqueous solution. Preferred embodiments of the process according to the invention with all the partial steps (a) to (f) as well as the partial aspects B, C and D relate to the preparation of compounds of formula (I), wherein
The process according to the invention is used to particular advantage to prepare the compound The aminocrotonylamino-substituted quinazoline derivatives of formula (I) obtained by the process according to the invention may subsequently be converted by known methods into the salts thereof, particularly into physiologically acceptable salts, for example into fumarates, tartrates or maleates. The conversion of the compound 4-[(3-chloro-4-fluorophenyl)amino]-6-{[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline obtained according to the invention into the corresponding dimaleate is preferred, as described in WO 2005/037824. The following Examples are intended to illustrate the invention in more detail: 20 g 7-chloro-6-nitro-3H-quinazolin-4-one are suspended in 80 ml acetonitrile and combined with 16.5 g phosphorus oxychloride. Then 10.8 g triethylamine are slowly added dropwise and the mixture is heated to about 80� C. After 5 hours a solution of 15.5 g 3-chloro-4-fluoroaniline in 100 ml dioxane is added dropwise and the mixture is stirred for another hour. Then 80 ml of water is added, the mixture is cooled to 20� C. and made slightly alkaline with KOH solution. The suspension is suction filtered, washed with water and ethanol and dried at 50� C. in vacuo. Yield: 29.07 g (89.5% of theoretical/dioxane solvate) m.p.: 272-274� C. 500 g 4-(3-chloro-4-fluoro-phenylamino)-7-chloro-6-nitro-quinazoline and 302 g (1.3 eq) benzenesulphinic acid sodium salt are suspended at 20� C. in 1500 ml DMF, heated to 90� C. and kept for 6 h at this temperature. After cooling the reaction mixture the suspension is suction filtered and the residue is rinsed with 1.5 l methanol, 10 l water and 0.5 l methanol. The residue is dried at 50� C. for about 12 h under reduced pressure. Yield: 631.2 g (86.2% of theoretical/DMF solvate). m.p.: 284-286� C. 810 g of 4-(3-chloro-4-fluoro-phenylamino)-7-(phenylsulphonyl)-6-nitro-quinazoline and 175.5 g (S)-3-hydroxytetrahydrofuran (1.3 eq) are placed at 20� C. in 1.04 l tert-butanol and 198 ml DMF, 2556 g K-tert.-butoxide in THF (24%) (3.6 eq) are added dropwise at 20� C. and then stirred for 4 h at 25� C. After a further 2 h at 40� C. the mixture is heated to 45� C. for about 2 h. 2.8 l of water are added and then about 3 l solvent are distilled off under reduced pressure. 2.8 l water are added again and about 900 ml solvent are distilled off under reduced pressure. After the addition of 1.6 l methanol the mixture is cooled to 20� C. The suspension is suction filtered and rinsed with a mixture of 3.2 l water and 1.6 l methanol. The residue is dried overnight at 50� C. under reduced pressure. Yield: 598.6 g (89.6% of theoretical). m.p.: 238-240� C. 100 g of 4-[(3-chloro-4-fluorophenyl)amino]-6-nitro-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline are hydrogenated in 400 ml DMF in the presence of 33.1 g Raney nickel and 18.7 g ammonium chloride at 40� C., until the calculated amount of hydrogen has been taken up. The catalyst is filtered off and the filtrate is added dropwise to 1.2 l water. The suspension is stirred for 2.5 h at 0� C., suction filtered and washed with 500 ml of water. The residue is dried overnight at 55� C. under reduced pressure. Yield: 84.36 g (97.1% of theoretical). m.p.: 120-130� C.
3.58 kg 1,1-carbonyldiimidazole (22.16 mol) are placed in 12.8 l of tetrahydrofuran and combined at 40� C. with 4.52 kg (22.16 mol) diethylphosphonoacetic acid, dissolved in 6.5 l tetrahydrofuran. The mixture is stirred for 30 minutes at 40� C. The solution thus obtained is designated solution A. 6.39 kg (17.05 mol) of N4-(3-chloro-4-fluoro-phenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine are placed in 26.5 l tetrahydrofuran and combined at 40� C. with solution A and stirred for 2 hours at 30� C. 64 l of tert.-butylmethylether are added to the suspension and after cooling to 20� C. the precipitate is removed by centrifuging. It is washed with a mixture of 16 l tetrahydrofuran and 16 l tert.-butylmethylether and then with 32 l water and dried at 50� C. Yield: 6.58 kg (69.8%) white crystals. Content: HPLC 99.1 Fl % 40 g of dimethylaminoacetaldehyde diethylacetal are heated to 40� C. in a mixture of 48 g conc. hydrochloric acid and 20 ml of water for 3 h. Then a solution of 42.4 g sodium pyrosulphite in 72 ml of water (sodium hydrogen sulphite solution) is added dropwise and the mixture is stirred for 1 h. 200 ml of ethanol are added and then the mixture is stirred for 2 h at 0� C. The suspension is suction filtered, washed with 160 ml of ethanol and dried at 45� C. in vacuo. Yield: 42.5 g (89.6% of theoretical) decomp.: from 180� C.
10 g of diethyl {[4-(3-chloro-4-fluoro-phenylamino)-7-((S)-tetrahydrofuran-3-yloxy)-quinazolin-6-ylcarbamoyl]-methyl}-phosphonate and 0.8 g lithium chloride are suspended in 60 ml of ethanol and cooled to −5� C. 11 g of 45% potassium hydroxide solution is added dropwise first of all and then 4.8 g dimethylaminoacetaldehyde-hydrogen sulphite adduct in 48 ml of water is added. The reaction solution is stirred for 1 h and then 60 ml of water are added. The suspension is suction filtered, washed with 40 ml of water and dried in vacuo at 45� C. Yield: 8 g (91% of theoretical) m.p.: 100-102� C. Patent Citations
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A delivery engine for QTI assessments
Wills, Gary, Hare, Jonathan, Kajaba, Jiri, Argles, David, Gilbert, Lester and Millard, David (2008) A delivery engine for QTI assessments. International Journal of Emerging Technologies in Learning (iJET), 3 (PMID:10.3991%2Fijet.v3i0.551 ).
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The IMS Question and Test Interoperability (QTI) standard has had a restricted take-up, in part due to the lack of tools. This paper describes the 'ASDEL' test delivery engine, focusing upon its architecture, its relation to item authoring and item banking services, and the integration of the R2Q2 web service. The tools developed operate with a web client, as a plug-in to Moodle, or as a desktop application. The paper also reports on the load testing of the internal services and concludes that these are best represented as components. The project first developed a Java library to implement the system. This will allow other developers and researchers to build their own system or incorporate aspects of QTI they want to implement
Item Type: | Article |
ISSNs: | 1863-0383 |
Related URLs: | |
Keywords: | E-assessment, Software tools, Question and Test Interoperability, QTI, e-learning |
Divisions: | Faculty of Physical Sciences and Engineering > Electronics and Computer Science > Electronic & Software Systems Faculty of Physical Sciences and Engineering > Electronics and Computer Science > Web & Internet Science |
ePrint ID: | 265980 |
Date Deposited: | 19 Jun 2008 18:55 |
Last Modified: | 20 May 2013 14:18 |
Further Information: | Google Scholar |
URI: | http://eprints.soton.ac.uk/id/eprint/265980 |
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This month on energy.gov, we'll be featuring clean energy technologies developed at the Energy Department's National Labs.
Over the last five years, American inventors and investors have made significant progress in developing and deploying key clean energy technologies -- supported by Energy Department policies.
Check out our best videos from 2013 -- from Secretary Moniz's first day on the job, to the rivalry between Edison and Tesla, to a visit to a solar-powered classroom.
From Albuquerque to Antarctica, we're geeking out over some of the coolest science photos we've ever seen.
Instead of making a New Year's resolution, this year make a home energy efficiency resolution. For the second year in a row, we are sharing our top 8 tips to save energy and money at home.
Solar power, zombie replicants and the Super Bowl all are featured in our top blog posts of 2013.
Check out our favorite energy-related photos!
The Energy Department's Los Alamos National Lab is tracking Santa Claus as he circles the globe the night before Christmas.
Next time you're at the airport or at a shop picking up a last-minute gift, you might see speciality vehicles powered by fuel cells, a clean energy technology that is helping bring your holidays to you.


text: An American legend comes to breathtaking life in this explosive epic Western starring Jason Patric, Robert Duvall, Gene Hackman and Wes Studi as Geronimo. Studi (The Last Of The Mohicans) gives a stunning performance as the fearless warrior who was the last Indian leader to surrender to the white man. Betrayed by the Army's legendary Indian fighter, General George Crook (Hackman), Geronimo leads a small band of warriors in escape. Pursued by a principled officer (Patric), a grizzled Army scout (Duvall), and a gung-ho West Point graduate (Matt Damon, Good Will Hunting), Geronimo evades capture through brilliant military strategy and cut-throat courage. His true story is both an action adventure and a spiritual journey through the heart of a warrior. MPAA Rating: PG-13 ©1993 Columbia Pictures Industries,Inc.All Rights Reserved.


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Agritourism and Direct Agricultural Marketing in Washington State: An Industry Profile
The objective of this report is to take stock of the activities, motivations, impacts and challenges faced by the farms in Washington as they relate to agritourism and direct marketing. We characterize the agritourism entrepreneurship and direct marketing activities in different counties of the State through a direct survey of industry respondents. Also, we determine the extent to which Washington's agritourism and direct marketing industry attracts local and foreign tourists. We find that the direct marketing industry in the State is well established but the agritourism activities are still developing. Most farms that conduct agritourism are small farms (with less than $250,000 of total sales), whereas direct marketing farms vary in size and include some larger farms in terms of sales. The primary reasons for operating are to earn additional income and educate the local populace regarding agricultural and local activities which illustrates economic and altruistic motives for farmers. Respondents feel that the main obstacles to the industry are State laws and regulations and concerns about liability. Farm operators in the industry rely on social networks to enhance production capacity as well as help increase demand for their product or service. Development of social networks may help overcome current and future obstacles of farms leading to overall growth of the industry.Download Info
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Paper provided by School of Economic Sciences, Washington State University in its series Working Papers with number 2010-10.Length: 43 pages
Date of creation: Oct 2010
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Handle: RePEc:wsu:wpaper:galinato-7
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Keywords: agritourism; direct agricultural marketing; Washington State;Other versions of this item:
- Gregmar Galinato & Suzette Galinato & Hayley Chouinard & Mykel Taylor & Phil Wandschneider, 2010. "Agritourism and Direct Agricultural Marketing in Washington State: An Industry Profile," Working Papers 2010-10, School of Economic Sciences, Washington State University.
- Q12 - Agricultural and Natural Resource Economics; Environmental and Ecological Economics - - Agriculture - - - Micro Analysis of Farm Firms, Farm Households, and Farm Input Markets
- Q13 - Agricultural and Natural Resource Economics; Environmental and Ecological Economics - - Agriculture - - - Agricultural Markets and Marketing; Cooperatives; Agribusiness
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A look at a new book on innovation and disruption.
Tags: Amazon, disruption, Innovation, The Age of the Platform
An essential read on decision making.
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Thoughts on one of the most prominent female CEOs today.
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A few thoughts on the inevitable disputes that arise among parties.
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Inconsiderate people lose credibility with you–and the opportunity to work with you again.
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On old mind-sets, new technologies, and the wrong questions to ask.
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Cream of Parsnip Soup with Fried Parsnip Nest and a Crab Meat and Wild Mushroom Relish |
In a gallon stock pot, heat the oil. When the oil is hot, add the onions. Season the onions with salt and pepper. Sauté the onions for 2 to 3 minutes, or until wilted. Add the parsnips and garlic. Season with salt and pepper. Stir in the stock and bring the liquid to a boil. Reduce the heat to a simmer and continue to cook for 1 hour, or until the parsnips are very tender, stirring occasionally. Using a hand-held blender, puree the soup until smooth. Slowly stir in the cream. Reseason with salt and pepper if needed. |
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A rash of six school bus-related crashes since late February has Palm Beach County schools and law enforcement officials wondering what they can do to keep children onboard safe from drivers on the road.
"There are so many people out there on the road driving distracted and in a hurry," said school district Senior Transportation Coordinator Sue Gorby. "People are not being mindful of their following distance, and there are a lot of aggressive drivers in Palm Beach County."
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text: John, I'm not entirely convinced the original was screen printed. The edges and corners strike me as being too sharp, but then I am guessing at how big this is, perhaps 3×5cm ?? The crown and interior writing might have been done by flooding with colour then cleaning the high spots. The outer writing might have been done using offset letterpress (letterpress transferred to a soft rubber plate/roller, then transferred to the plaque). Nowadays it might be possible to use a photopolymer plate to do this. The typeface could be identified but the outline (in particular the crenellations around the crown) would have to be done from a photo. It might take a few tries to get the correct paint consistency though. The plate looks like aluminum; is it possible that either or both of these colours are done using coloured anodizing? The gold might be but perhaps the blue isn't (if it were you would probably not be able to see ghosts of the "TER" in "AQUA MASTER"). There is some text that might be hard to figure out: the lower right appears to say "MADE IN USA" and perhaps the lower left says "SERIAL NO." There are a few online images of what the plate should look like. It appears that there is a letter painted in blue just before the serial number ("R" in the reference photo I found) that might be hard to recover. Can the plate be removed from the regulator? It is flat, curved, or domed? -Kevin Martin the Papertrail Handmade Paper & Book Arts New Dundee, Ontario www.papertrail.ca


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Stocking Stuffers for Young Men - Gift Cards & Memberships
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They say it's the little things in life that matter. The treats inside stockings are a perfect example, as they are a great way to express wit, or spoil someone with little luxuries, or share small gadgets that will make life so much easier.... Read More »
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While a goat may not seem like the sexiest of animals, you can't help but reconsider after meeting a Capricorn man. As surefooted, agile and tenacious as a mountain goat, your favorite Capricorn is most at home scaling mountains and navigating... Read More »


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Journal of Applied Mathematics
Volume 2013 (2013), Article ID 802791, 7 pages
Algorithms for Some Euler-Type Identities for Multiple Zeta Values
Department of Mathematics, Central South University, Changsha, Hunan 410083, China
Received 21 December 2012; Accepted 11 January 2013
Academic Editor: C. Conca
Copyright © 2013 Shifeng Ding and Weijun Liu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Multiple zeta values are the numbers defined by the convergent series , where , , , are positive integers with . For , let be the sum of all multiple zeta values with even arguments whose weight is and whose depth is . The well-known result was extended to and by Z. Shen and T. Cai. Applying the theory of symmetric functions, Hoffman gave an explicit generating function for the numbers and then gave a direct formula for for arbitrary . In this paper we apply a technique introduced by Granville to present an algorithm to calculate and prove that the direct formula can also be deduced from Eisenstein's double product.