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Royal WES5000 Wireless Speaker iPod Docking Station
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Tunis — Employment and Vocational Training Minister Abdelwaheb Maatar conferred, on Tuesday in Tunis, with International Labour Organisation (ILO) Director-General Guy Ryder. During the meeting both sides evoked the employment strategy in Tunisia, according to the Ministry's statement.
Tunis Afrique Presse (Tunis)
Tunisia: Employment Minister Confers With ILO Director-General
15 January 2013Copyright © 2013 Tunis Afrique Presse. All rights reserved. Distributed by AllAfrica Global Media (allAfrica.com). To contact the copyright holder directly for corrections — or for permission to republish or make other authorized use of this material, click here.
AllAfrica aggregates and indexes content from over 130 African news organizations, plus more than 200 other sources, who are responsible for their own reporting and views. Articles and commentaries that identify allAfrica.com as the publisher are produced or commissioned by AllAfrica.


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JW: If you could choose, would Juliet end up with Jack or Sawyer?
EM: I don't know! I'm so happy she had the time that she had with Sawyer because I always thought of Juliet as kind of a POW. That was my take on her. When she was with Sawyer, you got to see that she was actually making peace with some of the more disreputable parts of her past with Ben and kind of coming back into that girl that we first met. And I say girl because that's kind of how I thought of her then. She's definitely a woman now, but she was so kind of naïve. So I really enjoyed her with Sawyer. But I like Sawyer and Kate. I'm very torn. I kind of wouldn't mind if we all just kind of traded every couple of years. And then [Juliet] can be with her sister and Julian and it all works out really well. So I really can't say one way or another. I really feel that time for Juliet, just in watching of it, with Sawyer, was probably one of the best things that happened in her life. Keep Reading


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We will share our piece of paradise with you. Only a five minute walk to the beautiful sand beach.
A newly refurbished and furnished one bedroom condo perfect for your vacation get-away. Ideal for retired couple or small family. The white sandy beach of the Gulf is only half block from this very friendly nine unit complex located on a quiet side street.
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Payment is usually accepted in the quoted currency (USD) unless the currency and the amount is specifically agreed in advance with the owner / advertiser.


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Are you getting better at distinguishing between political spin and substance? You probably are given the growing number of Federal Government examples!
How can you distinguish between spin and substance? Well, it's fairly simple when you can spot the obvious signs.
First up, you have the grandiose statement. Some examples include: "we are going to have a tough petrol cop on the beat, ensuring that motorists are not paying a cent more than they have to at the bowser", "the greatest moral challenge" and "building the education revolution".
Talk of a tough petrol cop is about giving us confidence that the petrol cop will be there to lock up the crooks. That's what we expect cops to do. Not paying a cent more for petrol is supposed to give us confidence that we're no longer going to be ripped off. That plays on our suspicions of a petrol price rip off.
Reference to the greatest challenge means we need to act fast so don't hold us up. A call to arms and a sense of urgency is intended to show leadership and, perhaps, even vision.
As for a revolution, well, old communists will probably remember what that really means.
Big statements make for big vote-winning promises. It's a bit like the big-talking used car salesperson trying to sell you an old used car or when a dodgy franchisor is trying to sell you a dud franchise. Big claims, slick sales pitch and that "don't worry about anything, just leave it to me" approach.
The problem is that big statements are usually needed to sell the particular dodgy car, franchise or government promise. The big statements are there to deflect from the inherent weaknesses or limitations of the government promise.
After the grandiose statements comes the predictably big price tag for the promise. A big price tag is supposed to assure us that the promise has been properly funded and that the promise will be carried out by the Government. Again, it's about promoting confidence in the promise being made by the Government.
Finally, there needs to be a reality check on the promise being made. Will implementing the promise actually make a difference and will the promise be carried out cost effectively?
The reality check is the challenging and pointy end as the government will deploy its spin doctors to keep repeating the mantra that the `promise is great, is able to be achieved and will make a real difference.' Anyone questioning that mantra will be criticised by the Government and its spin doctors.
Sadly, there may only be a few questioning the mantra as anyone questioning the government is likely to miss out on government consultancies or appointments. Then there are those who don't question the mantra because of a conflict of interest arising from being a recipient of government funding or holding a government or business consultancy.
So, the government may even "get away" with the spin. That's at least until the promise is not carried out, doesn't achieve anything tangible or is just some kind of financial or other disaster.
Here it's useful to look at a couple of examples of spin.
Take the so-called tough petrol cop on the beat we were promised by Wayne Swan. Selling the idea of an ACCC Petrol Commissioner without any new powers to rein in the oil companies, and major retailers on petrol prices was always going to be tough. There was already an ACCC with commissioners. What was a new ACCC Petrol Commissioner with no new powers going to do that the ACCC and the other existing Commissioners were not already doing?
Sounds like a gimmick. Then when a Petrol Commissioner is appointed all you generally hear from him is that there is nothing wrong with petrol prices. Well, if you accept that there is nothing wrong with petrol prices, then why do we need a Petrol Commissioner?
Of course, oil companies and the major retailers like Coles and Woolworths will play different games at different times. So what the Federal Government should have done is given the Petrol Commissioner new specific powers. That's the difference between spin and substance and the difference between a gimmick and real competition law reform.
Appointing a Petrol Commissioner wasn't enough for the Federal Government. While the ACCC has long had one Deputy Chair, the Government decided to appoint another one in May 2008. This second Deputy Chair was to have responsibility for small business issues.
The only problem is that a second Deputy Chair came at a considerable cost to the taxpayer and again this new appointment was not given any new legislative powers to deal with small business issues. Now we were to have two ACCC Deputy Chairs and you had to wonder why.
Sounds like another gimmick. That' especially so when you hear that the South Australian State Labor Government has, to its credit, been trying to establish a new Small Business Commissioner with the ability to assist small businesses in a real and meaningful way when they have disputes with larger businesses.
The South Australian Small Business Commissioner will also be able to go to court to seek financial penalties for breaches of mandatory industry codes of conduct under the South Australian Fair Trading Act. Importantly, the South Australian Commissioner will also be able to issue infringement notices for breaches of such codes. These are real powers with real benefits for small businesses – that's substance!
The second Deputy Chair at the ACCC could have been given the same powers being proposed for the South Australian Small Business Commissioner. It's not too late for the Federal Government to give the second Deputy Chair those new powers.
In the absence of giving the appointees any new powers, it's inevitable that appointing a Petrol Commissioner or a second Deputy Chair at the ACCC sounds more like political spin than substance.
With no shortage of examples of political spin we are certainly getting better at spotting the spin. Let's hope that the political spin doesn't spin totally out of control as that's a sure way for the Federal Government to lose the next election!
Most commented
Kipling says:
Wow an article of spin about spin…
You are a Liberal stooge there is no doubt about that. Clearly you only see the spin from one side of the fence, which either smarts of ignorance or, worse, deliberate one eyed disengenous SPIN…
As to petrol pricing, it seems pretty obvious that this is more about deregulation of that industry, petrol companies pretty much call the shots on their pricing games. The consumer could address this issue very effectively, if they could be bothered, but being in Australia, apathy seems to rule. We are all just victims of the bigger world. Of course, judging from your piece, you are no victim but a willing participant in promoting the spin.
Banking also self regulates, and since it does we have not only seen the implementation of "fees" being charged so an individual can access their own money, which they presumably earned by honest methods, but a steady and unrestrained increase in fees. To my mind the obvious question here is how the hell did banks make a profit before they took fees from those whose money they are utlising? I think there is a hint to the answer in the way the question is framed.
What about the self regulating legal fraternity? Apparently the legal professionals do not believe the average citizen is well enough informed to be able to judge the conduct of a lawyer or solicitor. Of course, from experience, the Legal Services Commissioner does not appear to be well enough informed either…
Essentially though, you are correct I thnk, we (the Australian public) are getting better at recognising most forms of spin. If it is stated by a poitical representative, then it will be spin. If one reads about it in main stream media then it is most likely spun. Pretty much, if anyone is telling you it is good for you, or they are not ripping you off then much spin is going on.
Well, that about wraps up my spin….
Mahhrat says:
So a politician spins, but your examples are all Labor party spins?
"Great Big New Tax", anyone?
Robert S McCormick says:
I have lost all confidence in all of our politicians- from all sides - State & Federal -
All we get from them is Political Point Scoring. We don't get policies all we get is chatter.
Mahhrat accuses Frank of only giving Labor Party spins. Maybe that is because it is always the Party in Government which indulges in the most spin. Currently we have a Labor Government in Canberra so the vast majority of spin comes from Labor.
If we are unlucky enough to get a Coalition Government in Canberra under the current Liberal leader Tony Abbott we will get every bit as much spin from them as we get from the ALP now.
Because, for the most part, Oppositions (be they ALP or Coalition) are really irrelevant, nit-picking, purveyors of negativity.
It would maybe help those who currently attack Abbott & his Coalition for their negativity - despite them voting, with the exception of the Carbon Tax Price & the inhumane Malaysian Solution, in favour of the vast majority of legislation put forward by Rudd & now Gillard since 2007 - if they checked out the voting pattern of the ALP during the 11 years Howard & his Coalition were in office. If the reports and claims made by non-labor sources are correct (always, when it comes to politicians & their minions very, very suspect reports & claims), and apparently in official Federal Parliamentary Records the ALP never voted in favour of any, other than that which favourably affects their wallets & purses, legislation put up by the then Federal Coalition Government.
Our self-interested, greedy Federal politicians passed legislation which prevents any future Prime Minister, as Kevin Rudd did in 2007, from freezing pay rises granted to them by the Remuneration Tribunal.
The latest bit of spin on that was that "The Remuneration Tribunal Members are appointed by the Governor-General"! Yes, the G-G may appoint them BUT the G-G does so based on the "Advice of the "Prime Minister". The politicians appoint their own IR Board & we know what that means don't we?
Spin is easy. Spin enables politicians to avoid making the tough decisions. All their Reports, Inquiries etc are nothing more than window-dressing - expensive window-dressing for example we are told that the brilliant Henry Tax Review cost a reported $10 millions. The current government has virtually just dumped it on a shelf somewhere in the bowels of Parliament House. Expensive spin, no fault of Dr Ken Henry, which, at present, the Coalition say they are going to take a good hard look at & say they will implement Dr Henry's reccommendations.
Mayhap that is all spin too!!
Steve says:
A key point of Franks article was this one:
"Sadly, there may only be a few questioning the mantra as anyone questioning the government is likely to miss out on government consultancies or appointments. Then there are those who don't question the mantra because of a conflict of interest arising from being a recipient of government funding or holding a government or business consultancy."
Governments -of all stripes - dominate most possible domestic sources of opposing experience and knowledge through current or potential funding.
Lots of NGOs are part-funded by governments and hence muted, and experts tend to want to be appointed to panels in the future. Consultanciesand contracts are threatened if its criticism is made public.
Academics appointed to reviews are entirely predictable based on their previously published work, so it is quite easy to pick the team of experts and academics that will deliver the report the govenment needs to sell a policy.
Anna C says:
I make it a rule to never believe anything that a politician has to say and I'm generally not disappointed.
9.30 am 12 October 2011 says:
Only Shane Warne, Bill O'Reilly, Clarrie Grimmett, Richie Benaud, Arthur Mailey, Jack Iversen . Stuart Mc Gill, CTB Turner, and Ashley Mallett have been good at spin in Australia ! The spin cupboard is now bare! Bettiing has now replaced spin in Aussie cricket!
9.30 am October 12 2011 says:
9.30 am October 12 2011 is a time without spin or "what ICB"
The Carbon Tax Vote results
For ( ALP) 74 Against (Coalition) 72
Carbon Tax help for Steel
For ( Labor) 75 Against (Coalition ) 71
Harold May says:
Trust in political leaders is at an all time low after various world financial crises were mainly caused by poor decision making by them. It can be said that the distrust in politicians is on par with the distrust we have towards lawyers and salesmen.
Coincidentally, the majority of these people are known to be glib speakers, able to move people with beautiful words and promises. Soon we will hopefully become immune to this spin, and demand cold hard prove instead.
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Same-sex couples celebrate with marriages in New Hampshire
By scarce January 2, 2010 8:00 am
(NECN/WMUR: Concord, N.H.) - It is a new year, and New Hampshire is recognizing same-sex marriage.
Early this morning, couples gathered at the foot
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"I just wanted to say a big thank you for Friday. The games were great, Matt was fantastic and it all ran really well! We will definitely contact you if we need games etc for any future events for our clients." Jack Morton Worldwide
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Gable Events will provide the traditional side stalls, lighting, small prizes and a smartly dressed operator for each stall plus £5 million public liability insurance and professional event management. Optional extras include side stall branding, theming, venue finding, catering and additional team building activities


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'Last Song' stars Miley Cyrus, Liam Hemsworth's 'sparkle' eyes
Nicholas Sparks talked to the Dish Rag exclusively about Miley Cyrus' input (her character's name, animals, no singing) into the script for his new film, "The Last Song."
And he was one of the first on the set to notice the chemistry between the award-winning singer and her movie love interest, Liam Hemsworth. He calls it "'sparkles' in their eyes."
Hemsworth was so convincing as a great boyfriend in the film that he landed the role in real life: Yup, he's Miley's main man. She says her mother cast him in the movie.
Way to go, Mom! If we were Miley, we'd let her pick out all our boyfriends.
Can't wait to see Miley and Liam's first kiss? "The Last Song" opens on March 31.
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well, you gotta say, young love! wooohhhh! happy for them guys!
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The Complete Works of M. de Montesquieu (London: T. Evans, 1777), 4 vols. Vol. 2.
Liberty Fund, Inc. is a private, educational foundation established to encourage the study of the ideal of a society of free and responsible individuals.
The text is in the public domain.
This material is put online to further the educational goals of Liberty Fund, Inc. Unless otherwise stated in the Copyright Information section above, this material may be used freely for educational and academic purposes. It may not be used in any way for profit.
ALMOST all civilized nations dwell in houses; from hence naturally arose the idea of building a house for God, in which they might adore and seek him, amidst all their hopes and fears.
And, indeed, nothing is more comfortable to mankind, than a place in which they may find the deity peculiarly present, and where they may assemble together to confess their weakness, and tell their griefs.
But this natural idea never occurred to any but such as cultivated the land; those who have no houses for themselves, were never known to build temples.
This was the cause that made Jenghis-Khan discover such a prodigious contempt for mosques* . This prince† examined the Mahometans, he approved of all their doctrines, except that of the necessity of going to Mecca: he could not comprehend why God might not be every where adored. As the Tartars did not dwell in houses, they could have no idea of temples.
Those people who have no temples, have but a small attachment to their own religion. This is the reason why the Tartars have in all times given so great a toleration‡ ; why the barbarous nations who conquered the Roman empire, did not hesitate a moment to embrace Christianity; why the savages of America have so little fondness for their own religion; why, since our missionaries have built churches in Paraguay, the natives of that country are become so zealous for ours.
As the deity is the refuge of the unhappy, and none are more unhappy than criminals, men have been naturally led to think temples an asylum for those wretches. This idea appeared still more natural to the Greeks, where murderers, chased from their city and the presence of men, seemed to have no houses but the temples, nor other protectors but the gods.
At first these were only designed for involuntary homicides; but when the people made them a sanctuary for those who had committed great crimes, they fell into a gross contradiction. If they had offended men, they had much greater reason to believe they had offended the gods.
These asylums multiplied in Greece. The temples, says Tacitus* , were filled with insolvent debtors, and wicked slaves; the magistrate found it difficult to exercise his office; the people protected the crimes of men as the ceremonies of the gods; at length the senate was obliged to retrench a great number of them.
The laws of Moses were perfectly wise. The man who involuntarily killed another, was innocent; but he was obliged to be taken away from before the eyes of the relations of the deceased: Moses therefore appointed an asylum† for such unfortunate people. The perpetrators of great crimes deserved not a place of safety, and they had none‡ , the Jews had only a portable tabernacle, which continually changed its place: this excluded the idea of a sanctuary. It is true, that they had afterwards a temple; but the criminals, who would resort thither from all parts, might disturb the divine service. If persons who had committed manslaughter, had been driven out of the country, as was customary amongst the Greeks, they had reason to fear that they would worship strange gods. All these considerations made them establish cities of safety, where they might stay till the death of the high-priest.
[* ]Entering the mosque of Bochara, he took the Koran, and threw it under his horse's feet. Hist. of the Tartars, p. 273.
[† ]Ibid. page 342.
[‡ ]This disposition of mind has been communicated to the Japanese, who, a it may be easily proved, derive their original from the Tartars.
[* ]Annal. lib. 2.
[† ]Numb. xxxv.
[‡ ]Ibid.


text: Banjo/trumpet-playing singer/poet Bill Taft has been one of Atlantas most musically interesting and creative fringe dwellers ever since the days of the legendary Mudd Shack. His collaborations with dearly departed local icons Benjamin (Smoke), Deacon Lunchbox, and the Jody Grind were progressively evolving variations that led ultimately to HUBCAP CITY (FROM BELGIUM). Taft, guitarist Matthew Proctor, and drummer Will Fratesi manufacture soundscapes and auditory portraits derived from their subjective life experiences filtered through a prism of alternating urban blight and hope. Of course, the group also has a song cycle inspired by the record reviews in Sassy magazine, too. If there is ever a documentary made on the Cabbagetown sound, Hubcap City (from Belgium) would be a vital component.


text:
After going from the starting lineup to the game-day inactive list in seven days, one would understand if rookie running back Mike Bell was a tad flummoxed over another hairpin curve in a rookie season that has seen more unexpected turns than a mountain road.
Bell, though, simply saw it as a message — one he clearly received.
"I've got to fight harder," he said. "You've got to get 2 and 3 (yards on carries). You can't accept 1(-yard-runs). I'm going in with a different attitude."
Only that, he believes, will get him back on the 45-man active roster for Sunday's showdown with the San Diego Chargers.
"I know they have a tough defense, but I played against a lot of tough defenses in college and I have the best offensive line, so I'm going to find a way to make some plays," Bell said. "I know the running game is looking for a spark, so if I get a chance, I'm definitely going to do it."
But his back-to-back games against Indianapolis and Pittsburgh were about as opposite as two performances can be. He gained 136 yards on 15 carries against the Colts; a week later he had two more rushes but 108 fewer yards.
"The only game that he didn't play at the level that I was hoping he would play in was the Pittsburgh game," Head Coach Mike Shanahan said, "but that doesn't mean that he is in the doghouse or anything."
"I don't think I did anything wrong to get into his doghouse," Bell said, "so he did what was best for the team and I think at that time he felt Nash deserved a chance and he did, so (Shanahan) did what was best for the team."
So now he must start anew, and attempt to prove once again to Shanahan and the offensive brass that he is that best option.
"I'm working hard, watching a lot of film, taking a lot of criticism and I'm just trying to get better," Bell said. "I watched some tape and thought I left some yards on the field (at Pittsburgh).
"I was just getting so frustrated, I probably started deviating from the system and the game plan, and that's a mental mistake, a rookie mistake and it's definitely a learning experience, so I'm just going to learn from that and just trust the system and trust myself."
And, he hopes, that will make his bosses trust him.
Tags: Mike Bell, Running backs, San Diego Chargers


text:
It's true that House Republicans (at least the Tea party faction) believe that they are on to a winner here. It is also true that they believed last year that Romney was going to win in a landslide. The question is, what will it take for the reality that conflicts with their belief to get thru to them?
Unfortunately, the evidence suggests that the answer may well be Nothing will get thru to them. The only option is for the sane members of the House GOP to decide that they are willing to buck the lunatics, even at the risk of losing the next primary -- simply because it is that is good for the country and they care about that.
AMERICA'S government has shut down for the first time in 17 years. Our correspondents discuss how it will affect the country's politics and economy


text:
Willow Smith brought her free-spirit/rocker-chic/wild-child steez to the Versace show for Milan Fashion Week. She's giving us Noisette's lead singer Shingai Shoniwa vibes. More pictures of Willow, Mommy Jada Pinkett-Smith and Amber Rose below:
We don't know how we missed this shot of Amber Rose at Ozwald Boateng for London Fashion Week, but um, would you call this charming or tacky???
SplashNews/Pacific Coast News


text:
- When Sunday, December 30, 2012 at 10 a.m.
- Where San Diego Convention Center, San Diego - View Map
- Age limit All ages
- Categories Community, Exhibits, Family
- Cost Free - $12
- Buy Tickets
Above: Promotional image of a car on display at the The San Diego International Auto Show.
The San Diego International Auto Show will feature over 400 2013 Model-year vehicles, ride and drives, expanded exotics salon and much more! From December 27-30, 2012 at the San Diego Convention Center.
Location: San Diego Convention Center, 111 West Harbor Drive San Diego, CA 92101 Google Maps
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Sequence in raw or FASTA format:
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [Homo sapiens (human)]
Gene Symbol | CDKN2B |
Entrez Gene ID | 1030 |
Full Name | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
Synonyms | CDK4I, INK4B, MTS2, P15, TP15, p15INK4b |
Gene Type | protein-coding |
Organism | Homo sapiens (human) |
Genome |
9 9p21 |
Summary | This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]. |
Disorder | MIM: 600431 |
hsa05222 | Small cell lung cancer |
hsa05203 | Viral carcinogenesis |
hsa05166 | HTLV-I infection |
hsa05200 | Pathways in cancer |
hsa04350 | TGF-beta signaling pathway |
hsa04110 | Cell cycle |
Pathway Interaction Database
myc_represspathway | Validated targets of C-MYC transcriptional repression |
smad2_3nuclearpathway | Regulation of nuclear SMAD2/3 signaling |
WP2261 | Signaling Pathways in Glioblastoma |
WP45 | G1 to S cell cycle control |
WP2256 | Integrated Pancreatic Cancer Pathway |
WP2377 | Integrated Pancreatic Cancer Pathway |
REACT_821 | Cyclin D associated events in G1 |
REACT_120734 | SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
REACT_71 | Gene Expression |
REACT_6844 | Signaling by TGF-beta Receptor Complex |
REACT_121061 | Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
REACT_115566 | Cell Cycle |
REACT_12627 | Generic Transcription Pathway |
REACT_111102 | Signal Transduction |
REACT_152 | Cell Cycle, Mitotic |
REACT_1590 | G1 Phase |
REACT_21267 | Mitotic G1-G1/S phases |
Homo sapiens (human) | CDKN2B | NP_004927.2 |
Pan troglodytes (chimpanzee) | CDKN2B | XP_003312069.1 |
Macaca mulatta (Rhesus monkey) | CDKN2B | XP_001107263.1 |
Canis lupus familiaris (dog) | CDKN2B | NP_001139741.1 |
Bos taurus (cattle) | CDKN2B | NP_001069362.1 |
Mus musculus (house mouse) | Cdkn2b | NP_031696.1 |
Rattus norvegicus (Norway rat) | Cdkn2b | NP_570825.1 |
Gallus gallus (chicken) | CDKN2B | NP_989764.1 |
Related articles in PubMed
- Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction. van Setten J, et al. Atherosclerosis, 2013 Jun. PMID 23561647.
- Elite model for the generation of induced pluripotent cancer cells (iPCs). Lai J, et al. PLoS One, 2013. PMID 23418593.
- Common genetic variants in the 9p21 region and their associations with multiple tumours. Gu F, et al. Br J Cancer, 2013 Apr 2. PMID 23361049.
- Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study. Johnson AD, et al. Circulation, 2013 Feb 19. PMID 23315372.
- Interferon-γ activates expression of p15 and p16 regardless of 9p21.3 coronary artery disease risk genotype. Almontashiri NA, et al. J Am Coll Cardiol, 2013 Jan 15. PMID 23199516.
See all (283) citations in PubMed
See citations in PubMed for homologs of this gene provided by HomoloGene
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Single nucleotide polymorphisms in CDKN2B gene is associated with neoplasms
Title: Common genetic variants in the 9p21 region and their associations with multiple tumours.
Complex regulatory variation affecting ANRIL and CDKN2B gene expression may contribute to increased risk for clinically apparent and subclinical coronary artery disease and aortic disease.
Title: Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study.
The epigenetic changes in p15(INK4b) methylation and ANRIL expression may involve in the mechanisms of chromosome 9p21 on CAD development.
Title: Methylation of p15INK4b and expression of ANRIL on chromosome 9p21 are associated with coronary artery disease.
Our study confirms the significant association between SNP rs1063192 (CDKN2B, previously shown to influence vertical cup-to-disc ratio and POAG at 9p21) and primary open-angle glaucoma in the Afro-Caribbean population of Barbados.
Title: CDKN2B polymorphism is associated with primary open-angle glaucoma (POAG) in the Afro-Caribbean population of Barbados, West Indies.
The 9p21.3 risk genotype does not affect the activation of CDKN2A and CDKN2B by interferon-gamma. Thus, another mechanism is likely to account for the coronary artery disease risk associated with this locus.
Title: Interferon-γ activates expression of p15 and p16 regardless of 9p21.3 coronary artery disease risk genotype.
It was found that depletion of JHDM1B reduced colony formation of acute myeloid leukemia-derived aldehyde dehydrogenasehi/CD34+ cells due to induction of p15Ink4b expression through direct binding to p15Ink4b promoter.
Title: JmjC-domain containing histone demethylase 1B-mediated p15(Ink4b) suppression promotes the proliferation of leukemic progenitor cells through modulation of cell cycle progression in acute myeloid leukemia.
Reduced CDKN2B expression and increased p53-dependent smooth muscle cell apoptosis may be one mechanism underlying the 9p21.3 association with aneurysmal disease.
Title: Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
The 9p21 coronary artery disease risk genotype was associated with reduced expression of p16(INK4a), p15(INK4b) and ANRIL.
Title: Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells.
The identification of SIX1 and CDKN2B variant was found to be associated more strongly with advanced open-angle glaucoma.
Title: Genetic investigation into the endophenotypic status of central corneal thickness and optic disc parameters in relation to open-angle glaucoma.
A SNP predisposing to type 2 diabetes mellitus, rs10811661 near CDKN2A/B, is associated with diabetic nephropathy in patients with type 1 diabetes mellitus.
Title: SNP in the genome-wide association study hotspot on chromosome 9p21 confers susceptibility to diabetic nephropathy in type 1 diabetes.
General protein information
- Preferred Names
- cyclin-dependent kinase 4 inhibitor B
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- cyclin-dependent kinase 4 inhibitor B
- p14-INK4b
- p14_INK4B
- p15-INK4b
- p15_INK4B
- CDK4B inhibitor
- p14_CDK inhibitor
- p15 CDK inhibitor
- CDK inhibitory protein
- multiple tumor suppressor 2
- cyclin-dependent kinases 4 and 6 binding protein
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Recently, Tracy Clark Flory asked me and two other sex educators to help her craft a sex ed quiz for adults. After all, she reasoned, if kids in the DC area will now need to answer standardized sex education test questions – shouldn't adults be up to speed as well?
The quiz questions I contributed are [...]
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text:
Award winners!
- The Yahoo Canada Awards winners have been announced!
- "If I were PM" winner Yahoo Canada Awards - Thu, 1 Nov, 2012
- Canada's Media Mogul winner: Don CherryYahoo Canada Awards - Sun, 11 Nov, 2012
- Canada's next Prime Minister winner: Justin TrudeauYahoo Canada Awards - Sun, 11 Nov, 2012
- Buzziest story winner: Canada's women's soccer teamYahoo Canada Awards - Tue, 13 Nov, 2012
- Canada's best ambassador winner: Clara HughesYahoo Canada Awards - Sun, 11 Nov, 2012
- Best comeback winner: Sidney CrosbyYahoo Canada Awards - Mon, 12 Nov, 2012
- Buzziest Canadian winner: Christine SinclairYahoo Canada Awards - Tue, 13 Nov, 2012
- Tip of the Year winner: always warm upYahoo Canada Awards - Thu, 8 Nov, 2012
- Greatest Achievement winner: Melissa MorrisYahoo Canada Awards - Thu, 8 Nov, 2012
- Beaver Tail winner: Michael J. FoxYahoo Canada Awards - Thu, 8 Nov, 2012
- Canadian Impact winner: Simple PlanYahoo Canada Awards - Sun, 11 Nov, 2012
- Ultimate Scandal winner: Kristen StewartYahoo Canada Awards - Thu, 8 Nov, 2012
- Shining Moment winner: Rosie MacLennan's gold medalYahoo Canada Awards - Thu, 8 Nov, 2012
- Memorable Moment winner: Dark Knight shootingYahoo Canada Awards - Thu, 8 Nov, 2012
- Top Story winner: 2012 London OlympicsYahoo Canada Awards - Thu, 8 Nov, 2012
- Grand slam winner:Higgs bosonYahoo Canada Awards - Thu, 8 Nov, 2012
- Letdown of the Year winner: Facebook's IPOYahoo Canada Awards - Thu, 8 Nov, 2012
- Biggest Blunder winner: Costa ConcordiaYahoo Canada Awards - Thu, 8 Nov, 2012
And The Nominees Are...
Justin Bieber
He has 26,885,847 Twitter followers and counting. A sample of his Tweets include: "BE GREAT!" "HARD WORK DEDICATION! #rehearsal" "if you are with me im never letting you go. we are in this for the long run. i love you all. #BELIEVE that! #Beliebers." One Tweet from the 18-year-old can make a difference between life and death (literally) as was shown when the pop star made a plea on Twitter on behalf of double lung transplant recipient Helene Campbell urging fans to become organ donors. He can even inspire Olympians, as was shown when he gave a shout out to Team Canada gymnast Dominique Pegg at the 2012 London Games. Not even Ryan Gosling can do that.
Tony Clement
Treasury Board President Tony Clement has a whopping 24,000 followers, and he tweets his adventures numerous times each day. Like a lot of social media celebrities, Clement got lambasted by the Twittersphere earlier this year after mocking a Globe and Mail editor's decision to move to Cuba and for calling a teenager a jackass, but he's leveled off since then.
Priscilla Chan
Zucks got married! And no, he didn't wear a hoodie and sports sandals. At 28, the planet's most successful social media superstar, Mark Zuckerberg, tied the knot this May with his longtime girlfriend Priscilla Chan. Seeing as the inventor of Facebook was worth an estimated $17 billion when he wed back in May, much of the talk was not of young love, but of the prenuptial agreement.
The wedding came just one day after Facebook hit the stock market, and after an initially gigantic public offering that made Zucks a billionaire, the newlyweds have been forced to watch as Facebook share prices have plummeted. Maybe they can take comfort in the fact that, as a recent medical school graduate, Chan can kick in and pay some bills if worst comes to worst.
Paul Bissonette
He's No. 12 in the Phoenix Coyotes program but Paul Bissonette is best known as @BizNasty2point0. The Coyotes' tough guy and owner of five career goals in the NHL is the league's most followed tweeter with more than 324,000 followers on his Twitter account.
Yahoo Canada Awards Buzz
Letdown of the Year: Facebook
The social network's failure … More »
"If I were the next Prime Minister"
If I were Canada's next Prime … More »
Beaver Tail: Michael J. Fox
When it came to your pick for … More »
Biggest Blunder: Costa Concordia
The Costa Concordia disaster … More »


text:
Please enter your travel dates.
Hotel in Florence (Duomo) near Cathedral of Santa Maria del Fiore
Located in the heart of Florence, this hotel is steps from Giotto's Campanile, Cathedral of Santa Maria del Fiore, and Battistero di San Giovanni. Also nearby are Ponte Vecchio and San Lorenzo Church.
Hotel Features
Hotel Bigallo provides a bar/lounge, 24-hour room service, wireless Internet access (surcharge), and dry cleaning/laundry services.
Room Amenities
In addition to cable television, guestrooms include refrigerators and bathrooms with shower/tub combinations and bidets.
Information missing or incorrect? Tell us!Hotel Amenities
- General
Hotel Bigallo features a library, multilingual staff, and dry cleaning/laundry services. High-speed wireless Internet access is available for a surcharge. A bar/lounge is on site where guests can unwind with a drink. This Florence hotel also offers tour assistance, 24-hour room service, and translation services. Parking is available onsite for a surcharge.
- Concierge desk
- Room service (24 hours)
- Parking (surcharge)
- Secretarial services
- Total number of rooms - 17
- 24-hour front desk
- Multilingual staff
- Translation services
- Tour assistance
- Dry cleaning/laundry service
- Elevator/lift
- Library
- Air-conditioned public areas
- Bar/lounge
- Safe-deposit box at front desk
- Parking nearby (surcharge)
- Luggage storage
- Wireless Internet access - surcharge
- Internet
Available in some public areas: Wireless Internet access - surcharge
- Parking
Parking (surcharge), Parking nearby (surcharge)
- Room Amenities
- Air conditioning
- Hair dryer
- Blackout drapes/curtains
- Direct-dial phone
- Refrigerator
- Wake-up calls
- Private bathroom
- Bidet
- Extra towels/bedding in room
- Shower/tub combination
- Cable TV service
- Electronic/magnetic keys
- Window opens
- In-room safe
- Rollaway/extra beds available
- Cribs/infant beds available
- Daily housekeeping
- Soundproofed rooms
- Climate control
- Dining
24-hour room service is available.
Policies & Fees
- Check-in
Check-in time starts at 2 PM
Minimum check-in age is 18
- Check-out
Check-out time is 11 AM
- Payment types
Accepted at this hotel: American Express, Diners Club, JCB International, MasterCard, Visa
- Pets
Pets not allowed
- General
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- Fees
- Unless otherwise indicated, the charges below are not included in the overall room price. If not included in the overall room price, they will be charged by the property at check-in or check-out. Charges can vary, for example, based on length of stay or the room you book. This property told us they will charge you for the following:
- A tax is imposed by the city: EUR 3 per person, per night, up to 7 nights. This tax does not apply to children under 12 years of age.
We have included all charges provided to us by the property. However, charges can vary, for example, based on length of stay or the room you book.The following fees and deposits are charged by the property at time of service, check-in, or check-out.- Fee for in-room wireless Internet: EUR 5.00 (for 24 hours, rates may vary)
- Fee for wireless Internet in business center: EUR 5.00 (for 24 hours, rates may vary)
- Self parking fee: EUR 25 per day
- Crib (infant bed) fee: EUR 10.00 per night
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
- Additional Details
Cash transactions at this property cannot exceed EUR 999.99, due to national regulations. For further details, please contact the property using information in the booking confirmation.


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Lexington, Mass., December 3, 2012 A new whitepaper sponsored by Imprivata, the leader in healthcare IT security, and developed by IDC Health Insights, "Imprivata Cortext: HIPAA Compliant Texting for Clinicians," reveals care team collaboration and productivity benefits of HIPAA compliant text messaging in the healthcare market.
"Our interviews with users of HIPAA compliant text messaging revealed a wide range of challenges using mobile devices in a healthcare setting before deploying a HIPAA compliant solution, including native phone texting is not HIPAA compliant, bring your own device (BYOD) demands, mobile device security concerns and the fact that not all clinicians are allowed to use mobile devices," said Lynne A. Dunbrack, Program Director, IDC Health Insights. "Our research revealed that lifting the security barrier that previously inhibited care providers from text messaging in a clinical environment allowed users, including cardiologists, radiologists, and anesthesiologists, to employ a wide range of departmental applications."
Despite the various departmental applications, IDC Health Insights' study identified three benefits that were consistent across clinical departments and workgroups, including ease of use which accelerates clinical adoption, improved collaboration and enhanced productivity. Three clinical use cases that support these benefits were documented in the IDC report, including:
- HIPAA-compliant text messaging helped Beaufort Memorial Hospital's cardiologists and nurses save time: When a catheterization (cath) lab was activated, time was of the essence to alert the percutaneous coronary intervention (PCI) team that a patient was being sent from the emergency department and needed to be prepped for the cardiologists. Nurses in the cath lab used text messaging to quickly alert the cardiologists on call when the patient would be ready.
- Ease of use accelerated HIPAA-compliant text messaging adoption among Melbourne Internal Medicine Associates (MIMA) home healthcare clinicians: Dozens of clinicians provide home care on a weekly basis and wanted to communicate with the home health nurses with whom they work.
- HIPAA-compliant text messaging enables improved collaboration among Memorial Healthcare OB physicians and nurses: Labor nurses used HIPAA compliant text messaging to keep the OBs informed of their patients' labor status or alerted them that they were needed in the labor and delivery unit because delivery was imminent or the mother and/or baby were in distress. The nursing staff appreciated that they could see that the text message was opened, as paging lacks a similar handshake.
"The findings from IDC Health Insights' research reaffirmed our belief that there is a significant need for HIPAA compliant text messaging in the healthcare market," said Omar Hussain, President and CEO, Imprivata. "We've been surprised at the broad range of departmental applications of HIPAA compliant text messaging and expect clinical use cases will continue to grow as HIPAA compliant text messaging becomes standard practice for care teams."
The HIPAA compliant text messaging users in the study identified best practices and lessons learned as they rolled out the application throughout their organization to start realizing the collaboration and productivity benefits. To learn more about this study and best practices for deploying by workgroup or department, download the whitepaper developed by IDC Health Insights, "Imprivata Cortext: HIPAA Compliant Texting for Clinicians."


text: I am convinced that it is still speed of the game and that he needs to read defenses 1/2 a second faster. Usually he is pretty good on the slants because it is a simple read. However when he drops straight back, he is taking too long to decipher the coverage. This indecision makes him rush his throw because he is getting the ball there late. It will get better.


text:
Select () or exclude () categories to narrow your recipe search.
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"This recipe is from the side of a Kraft Peanut Butter jar. It's super easy and perfect for people who can't eat gluten. Substitute Splenda granular for sugar for a lower calorie version. I use the reduced fat peanut butter."
Prep Time: 10 mins
Total Time: 25 mins
"While I have dozens of chicken salad recipes I made this last night for a church supper and put it at the top of my list favorites. The honey and Dijon mustard really make this salad stand out. We use a slice of white and a slice of wheat bread to make the sandwiches, and also cut them into fourths making triangles. Serving these on a pretty platter,..."
Ingredients: pepper, Dijon mustard, honey...
Prep Time: 20 mins
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"My family loves green bean casserole but I'm a bit weary of the regular old recipe. Found this from Ms. Deen and plan to try for our next holiday meal."
Ingredients: French fried onion rings, cream of mushroom soup...
Prep Time: 10 mins
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Pet Frogs Making People Sick with Salmonella
Raw meat is a notorious Salmonella carrier. It can also be found on unclean kitchen counters. An investigation published this week in the journal of Pediatrics suggests we should also look for the deadly bacteria in pet frogs.
Investigators from public health agencies across the United States found that African dwarf frogs are causing a nationwide outbreak of a specific Salmonella strain in children.
A group of health professionals make up the Salmonella Typhimurium Outbreak Investigation Team, which is part of the Centers for Disease Control and Prevention. Recently, the team has been examining the effects of African dwarf frogs on people's health.
Source: CNN. Read full article. (link)
Editor's Note: We invite comments and request that they be civil and on-topic. We do not moderate or assume any responsibility for comments, which are owned by the readers who post them. Comments do not represent the views of Reason.com or Reason Foundation. We reserve the right to delete any comment for any reason at any time. Report abuses.


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I am so excited. The kids and I booked Madison's birthday party last night (yes, I know her birthday isn't until January. However, I'm anal. I look to book things early. I mean I've already talked to the caterer for Madison's first communion which isn't until May. Yes, I know I am crazy).I have been trying to decide what to do for Madison's birthday. ...continue reading
21 Jul | 2011
Oak Lawn Deals: The Ultimate Site for Local Deals and Bargains in Oak Lawn
posted by 5 Comments
My Thoughts, Ideas, and Ramblings is happy to announce that they will be launching two new deal websites called Oak Lawn Deals and Lisa's Mom Deals. One of the main objectives is to feature and showcase great local businesses and services in Oak Lawn. Through this exciting new community-based site, users will have the opportunity to discover new services and ...continue reading


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The Donate Life NC registry does not include whole body donation, as being an organ donor usually prevents whole body donation. In some instances medical schools will accept eye-only donors, but each program has different requirements.
If an individual wishes to make a gift of their whole body to a body donation program in North Carolina, they should make advance arrangements with a specific medical school or research program.
- UNC School of Medicine Body Donation Information (FAQs and Forms)
- Duke University School of Medicine Anatomical Gifts Program (FAQs and Contact Info)
- East Carolina University: Department of Anatomy and Cell Biology of the Brody School of Medicine (Forms)
- Wake Forest University: The donation of bodies for medical education, or Anatomical Bequeathal Program, is administered by the Department of Neurobiology and Anatomy. For more information, please call (336) 716-4369.
- Fayetteville Technical Community College Mortuary Science Program (Anatomical Donation Guidelines and Forms)


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Cheap Flights from Seattle to Myanmar
Did You Know?
- There are 32 countries in the same zone as Myanmar.
- There are 34 cities with flights to Myanmar.
- United has the most flights to Myanmar.
- The longest flight to Myanmar is 1,709 miles.
- The currency symbol for MMK is MMK.


text: Brooding on the nose with dark fruit, smoke and dark spices. More black fruit follows on a full-bodied palate with some tannic grip and a pleasantly bitter tarry note. Decant 2 hours and enjoy with hearty meat dishes. Food pairings: barbecued meats and mushrooms, hard cheeses. Best Beef WineThis Leone De Castris Riserva Salice Salentino 2009 was reviewed June 8, 2013 by Natalie MacLean


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July 16th is getting closer now! I'm Arch Angels and gonna meet this awesome guy @DavidArchie in Jakarta! See you guys there! :D


text:
Crown Publishers, Inc. | Crown Publishers, Inc.
Old flames are reignited in the fifth and final book in the New York Times bestselling Jessica Darling series.
Captivated readers have followed Jessica through every step and misstep: from her life as a tormented, tart-tongued teenager to her years as a college grad stumbling toward adulthood. Now...
The story of how three too smart, too striking and too uncertain to be standard "pretty girls". How they grow together and grow apart, fall in and out of love and try to figure out what it means today to be a woman.
No-Man's Lands describes my journey as I retrace the travels of Homer's hero Odysseus as he made his way from Troy to Ithaca after the Trojan War. As he faced the Cyclops, Scylla and Charybdis, the Sirens, and many other challenges Odysseus learned a lot about how to face life as a man in middle...
A subllmely funny, intellectually provocative journey through the tattoos on Peter Trachtenberg's body, each of which represents a theme or episode in his life. Lust. Faith. Penance. A funerary rite in Borneo, complete with demonic possession. A dope-sick interlude in a junkies' church. A...
An irresistible reimagining of the Robin Hood legend, Maid Marian brings to life the rollicking--and romantic--world of the Middle Ages.
An orphan and heiress to a large country estate, Marian Fitzwater is wed at the age of five to an equally young nobleman, Lord Hugh of Sencaster, a union that...
She's beautiful," writes Irish-American art historian Patricia Dolan in the first of the journal entries that form The Music Lesson. "I look at my face in the mirror and it seems far away, less real than hers."
The woman she describes is the subject of the stolen Vermeer of the novel...
A young photographer just winning recognition for her work, Harriet Rose is possessed by an eccentric sensibility, the product of a childhood in which privilege and haunting loss were intertwined. At twenty-six, it seems that things are going her way at last: she has found love with a painter,...
Alice Cooper delivers his colorful memoirs in a unique fashion. In addition to his life story as a rock 'n' roll icon, Golf Monster also features the 12 Steps to becoming a pure golf addict. Cooper rifles the golf ball straight down the fairway almost every time, and endorse Calloway clubs. Alice's...
"Betcha I can tell ya / Where ya / Got them shoooes. / Betchadollar, / Betchadollar, / Where ya / Got them shoooes. / Got your shoes on your feet, / Got your feet on the street, / And the street's in Noo / Awlins, Loo- / Eez-ee-anna. Where I, for my part, first ate a live oyster and first saw a...


text:
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text:
Daily Travel Photo: Notre Dame Gargoyles
I caught these Gargoyles of Notre Dame during a night walk around the church. They're fantastic!
I'll see you out there…!
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I caught these Gargoyles of Notre Dame during a night walk around the church. They're fantastic!
I'll see you out there…!
Hey adventurers,
Happy Monday. Paris is a great city to photograph (be sure to check out my tips on taking photos of the Eiffel Tower and Arc de Triomphe before you visit). But it's an even better city to photograph in black and white. Here are a few of my favorites.
Have a favorite? Share by commenting. You can also upload your best black and white photo on the adventureswithben facebook page.
The Arc de Triomphe at the end of the Champs Elysee in Paris, France is one of the country's most recognized landmarks (aside from the Eiffel Tower). It's located in the center of a traffic circle with cars whizzing around. It makes taking a clear picture of the monument without a truck in the way very difficult.
So instead of fighting the traffic, use it to your advantage and take a picture of the Arc de Triomphe with Light Trails (the blurry streaks of lights at the bottom of the photo). Here are some photography tips for your next trip to Paris.
Hey Adventurers,
Today's post is a quickie. Something different from the normal, wordy posts. I thought I'd share with you one of my favorite photos I took of the Eiffel Tower. Took this in October of 2008.
If you'd like to take a photo of the Eiffel Tower like this, here's some tips to help you replicate it:
Sometimes when I am reading through books, magazines or websites there are places in the world that I see and I say, "I would love to go there, but I'll never make it". The Mont Saint Michel in Normandy, France was one of those places. Why was it so difficult? Simply because it is far from Paris and removed from the normal tourist route. In order to visit the Abbey travelers must board a train to nowhere. Arriving in a little town called Pontorson, they must board a city bus to the Mont Saint Michel. The logistics of timing it all turn off many. With a risky spirit and some luck, Brian and I took the chance for a once in a lifetime moment.
It's a sandwich, calm down. Find out where it's hanging (the sign) later this week.


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Rape aggression defense (R.A.D.) or other self-defense classes - Are they available at Columbia? | related questions Originally Published: October 11, 2002 - Last Updated / Reviewed On: February 24, 2012 |
Share this |
Hi Alice,
Where can I go for a RAD (Rape Aggression Defense) class in Columbia University?
Dear Reader,
The Rape Aggression Defense system, or R.A.D., is a comprehensive course that instructs women in self-defense techniques and tactics for the real world. Available throughout the United States and Canada, R.A.D. programs teach women of all ages and abilities the skills and knowledge they would need to protect themselves. Educational, interactive, and participatory, the topics covered include awareness and prevention basics, risk reduction and risk avoidance preparation, and hands-on training in self-defense. R.A.D. program schedules and fees vary by type of course. For more information, or to find a R.A.D. course near you, check the R.A.D. website. Although some universities and colleges offer R.A.D. programs on their campuses, Columbia University does not. There are, however, instructors in the New York City area and the website lists the most up-to-date directory of NYC instructors.
Columbia's Dodge Fitness Center offers for credit Karate classes each semester for undergraduate students. Although the classes are not self-defense in focus, they can help build self-confidence, strength, and flexibility. For more information about the classes, including the schedule and registration, you can call the Columbia Physical Education Department at x4-3439. You can also check out the Columbia Directory of Classes. Columbia also has Club Sports, such as Aikido, Brazilian Jiu Jitsu, Goju Ryu, Moy Yee Kung Fu, Shotokan Karate, and Tae Kwon Do, which are open to all students, faculty, staff, and alumni. Club Sports center on athletic interest, from recreational to instructional to competitive activity, and require membership fees to keep running. More on these options can be found at the Club Sports Office at 332 Dodge Fitness Center or by dialing x4-5911.
While there is likely no harm in a person learning strategies for self-defense, programs like R.A.D. are no substitute for continuing efforts to prevent assaults and other forms of violence in society. Some have even postulated that self-defense classes can create a false sense of security in some participants. Further, since these efforts fail to recognize that the majority of sexual assaults are by an acquaintance, the techniques covered may only really be useful in a surprise attack type of situation.
Have you looked into the many efforts at Columbia dedicated to preventing sexual violence? There are a variety of different workshops and involvement opportunities for both students and faculty/staff offered that address such topics as supporting survivors of sexual assault, being a first responder or a bystander to an assault, intimate partner violence, unlearning rape myths, and risk–reduction strategies. Check out the Sexual Violence Response website for information about sexual violence prevention workshops and other opportunities to help make campus a healthier and safer place for all.


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Tattoo Age
Valerie Vargas - Part 1
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Valerie Vargas grew up in Scotland, but has lived and worked in London for the last five years. You can find her at Frith Street Tattoo in SoHo, where she's known for doing the prettiest "lady heads" in the world. Valerie has only been seriously tattooing since 2007, so she's proof that talent and hard work will never fail you.


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Here are a couple of cute chicks that are easy to make! This would be a fun craft for the kids to help out with. I have the directions linked here: http://craftklatchwithmona.blo...-craft-tutorial.html Mona | |||
Very cute! I'm sure kids would get a kick out of making these! | ||||
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Product Pathways - PathScan ELISA
PathScan® Total Chk1 Sandwich ELISA Kit #7872
PhosphoSitePlus® protein, site, and accession data: Chk1
No. | Size | Price | ||
7872S | 1 Kit (96 assays) | --- | In Stock | --- |
7872 | carrier free and custom formulation / quantity | email request |
When ordering five or more kits, please contact us for processing time and pricing at firstname.lastname@example.com.
Already purchased this product? Write a Review.
Kit Includes | Volume | Solution Color |
Chk1 Ab Coated Microwells | 96 tests | |
Chk1 Detection Ab | 11 ml | Green |
Anti-rabbit IgG, HRP-linked Antibody | 11 ml | Red |
TMB Substrate #7004 | 11 ml | Colorless |
STOP Solution #7002 | 11 ml | Colorless |
Sealing Tape | 2 sheets | |
ELISA Wash Buffer (20X) | 25 ml | Colorless |
ELISA Sample Diluent | 25 ml | Blue |
Cell Lysis Buffer (10X) #9803 | 15 ml | Yellowish |
Note: 12 8-well modules – Each module is designed to break apart for 8 tests.
Storage: Kit should be stored at 4°C with the exception of Cell Lysis Buffer, which is stored at –20°C (packaged separately).
Species-Reactivity |
Human |
The PathScan® Total Chk1 Sandwich ELISA Kit is a solid phase sandwich enzyme-linked immunosorbent assay (ELISA) that detects endogenous levels of Chk1. A Chk1 Mouse Antibody has been coated onto the microwells. After incubation with cell lysates, Chk1 (phospho and nonphospho) is captured by the coated antibody. Following extensive washing, a Chk1 Rabbit Detection Antibody is added to the captured phospho and nonphospho Chk1 protein. Anti-rabbit IgG, HRP-linked Antibody is then used to recognize the bound detection antibody. HRP substrate, TMB, is added to develop color. The magnitude of the absorbance for this developed color is proportional to the quantity of total Chk1.
Antibodies in kit are custom formulations specific to kit.
Specificity / Sensitivity
CST's PathScan® Chk1 Sandwich ELISA Kit #7872 detects endogenous levels of total Chk1 protein. As shown in Figure 1, a significant induction of Chk1 phosphorylation at Ser317 can be detected in HeLa cells following treatment with UV using the Phospho-Chk1 (Ser317) Sandwich ELISA Kit #7870. The levels of total Chk1 (phospho and nonphospho) remain unchanged as shown by Western analysis and by PathScan® Total Chk1 Sandwich ELISA Kit #7872 (Figure 1). This kit detects proteins from the indicated species, as determined through in-house testing, but may also detect homologous proteins from other species.
ELISA - Western correlation
Figure 1. Treatment of HeLa cells with UV stimulates phosphorylation of Chk1 at Ser317, detected by the PathScan® Phospho-Chk1 (Ser317) Sandwich ELISA Kit #7870, but does not affect the levels of total Chk1 detected by PathScan® Total Chk1 Sandwich ELISA Kit #7872. HeLa cells (80-90% confluent) were treated with 100 mJ/cm2 UV with 1 hour recovery at 37ºC. The absorbance readings at 450 nm are shown in the top figure, while the corresponding Western blots using Chk1 Antibody #2345 (left panel) or Phospho-Chk1 (Ser317) Antibody #2344 (right panel) are shown in the bottom figure.
Chk1 kinase acts downstream of ATM/ATR kinase and plays an important role in DNA damage checkpoint control, embryonic development, and tumor suppression (1). Activation of Chk1 involves phosphorylation at Ser317 and Ser345 and occurs in response to blocked DNA replication and certain forms of genotoxic stress (2). While phosphorylation at Ser345 serves to localize Chk1 to the nucleus following checkpoint activation (3), phosphorylation at Ser317 along with site-specific phosphorylation of PTEN allows for re-entry into the cell cycle following stalled DNA replication (4). Chk1 exerts its checkpoint mechanism on the cell cycle, in part, by regulating the cdc25 family of phosphatases. Chk1 phosphorylation of cdc25A targets it for proteolysis and inhibits its activity through 14-3-3 binding (5). Activated Chk1 can inactivate cdc25C via phosphorylation at Ser216, blocking the activation of cdc2 and transition into mitosis (6). Centrosomal Chk1 has been shown to phosphorylate cdc25B and inhibit its activation of CDK1-cyclin B1, thereby abrogating mitotic spindle formation and chromatin condensation (7). Furthermore, Chk1 plays a role in spindle checkpoint function through regulation of aurora B and BubR1 (8). Research studies have implicated Chk1 as a drug target for cancer therapy as its inhibition leads to cell death in many cancer cell lines (9).
- Liu, Q. et al. (2000) Genes Dev 14, 1448-59.
- Zhao, H. and Piwnica-Worms, H. (2001) Mol Cell Biol 21, 4129-39.
- Jiang, K. et al. (2003) J Biol Chem 278, 25207-17.
- Martin, S.A. and Ouchi, T. (2008) Mol Cancer Ther 7, 2509-16.
- Chen, M.S. et al. (2003) Mol Cell Biol 23, 7488-97.
- Zeng, Y. et al. (1998) Nature 395, 507-10.
- Löffler, H. et al. (2006) Cell Cycle 5, 2543-7.
- Zachos, G. et al. (2007) Dev Cell 12, 247-60.
- Garber, K. (2005) J Natl Cancer Inst 97, 1026-8.
Application References
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know!
- 7872:
- Sandwich ELISA
Companion Products
- 7870 PathScan® Phospho-Chk1 (Ser317) Sandwich ELISA Kit
- 2360 Chk1 (2G1D5) Mouse mAb
- 12302 Phospho-Chk1 (Ser317) (D12H3) XP® Rabbit mAb
- 2344 Phospho-Chk1 (Ser317) Antibody
- 2347 Phospho-Chk1 (Ser280) Antibody
- 2349 Phospho-Chk1 (Ser296) Antibody
- 2348 Phospho-Chk1 (Ser345) (133D3) Rabbit mAb
- 7074 Anti-rabbit IgG, HRP-linked Antibody
- 9803 Cell Lysis Buffer (10X)
- 7004 TMB Substrate
- 7002 STOP Solution
For Research Use Only. Not For Use In Diagnostic Procedures.
PathScan® is a trademark of Cell Signaling Technology, Inc.
Cell Signaling Technology® is a trademark of Cell Signaling Technology, Inc.


text:
The finish to the 2012 season was a bitter disappointment for Broncos Country. It was made worse by the fact Denver had a brilliant regular season and surpassed expectations across the board. The cautious hopes in the preseason were overhauled in the midst of a magical 11-game winning streak during the year. That fact made the playoff loss hurt even more.
But with some time to regroup many of the fans have come to realize the season was a big success. Furthermore, it may be the springboard needed for this team to accomplish something very special in the near future.
The 2012 season will always be remembered by the last second playoff loss and what could have been; no doubt about that. But most thought Denver would be lucky to finish the year with a winning record. There were serious questions about Peyton Manning's health and constant reminders that the Broncos faced one of the toughest schedules in the league. My season preview predicted that Denver would win the division, but I had them doing it at 10-6 with the acknowledgement it would be extremely difficult.
In fact, it was easier than anyone dreamed. The rest of the division was pitiful and Denver dominated the regular season. Their 13-3 record was 7 games better than the second place Chargers if you count the tiebreaker, and the Chiefs and Raiders were two of the worst teams in the league. The defense blossomed under Jack Del Rio and the outstanding performance of their young playmakers. Peyton Manning and the offense was an absolute machine. The only thing that slowed them down in the playoffs was the bitter cold temperature and injuries in their backfield.
Make no mistake, what Denver accomplished last season was no fluke. Expect to see the Broncos back in the playoffs for as long as Manning wears the Orange & Blue. They will have several more chances at a deep playoff run over the next few years. This should make the fan base ecstatic about what lies ahead.
For the first time in a long time there are no questions surrounding the quarterback situation. Quarterback controversies and Manning Watch 2012 is in the past. The Broncos will be returning their defensive coordinator for a second straight season! That is certainly a change from the revolving door that has been in place for the better part of a decade. The rest of the division is undergoing organizational overhauls. Expect them to experience some growing pains for a while. The Denver offense and defense, both top 5 units in 2012, should be improved with another offseason in which John Elway can work his magic. The roster holes that were exposed in the playoffs will be filled in some fashion. The biggest story going into training camp will be how improved are they at positions of need?
This offseason will be a fun one. There will be plenty of player transactions and Denver is a big free agent destination after the franchise reinvented itself last year. They also had the most cap space available of any AFC West team when the offseason began which means there is plenty of room for improvement. Although Denver doesn't have a pick until late in the first round of the draft it's a great year to be looking for linemen, something the Broncos will definitely be doing. The biggest worry for the fans isn't whether the team will be successful it's how far can they go when the playoffs come around?
The sun has risen again in Broncos Country, and there are bright days ahead.
Make sure to follow @MileHighMonday on Twitter and Predominantly Orange on Facebook.
Topics: Afc West, Denver Broncos, John Elway, Peyton Manning


text:
July Special!
Get the 2014 Collector Car Price Guide Value Pack for only $39.99. There are
only 50 available!
2014 Collector Car Price Guide Value Pack
Check these out too:
2013 Collector Car Price Guide
Standard Catalog of American Cars 1946-1975
Standard Catalog of Pontiac 1926-2002
Old Cars Guide to Auto Restoration CD
- Automotive Marketplace
Tag Archives: Scottsdale
RM Auctions realizes $36.4M at Arizona sale
PHOENIX – RM Auctions, the world's largest collector car auction house for investment-quality automobiles, kicked off its 2013 auction season on a strong note Friday, Jan. 18, realizing an impressive $36.4 million in sales (including 10% buyer's premium) with a … More
Categories: Auction News, Hobby News
Tags: auction, car auction, rizona auctions, RM Auctions, Scottsdale
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Mustangs among Russo and Steele top lots at Scottsdale
The 13th annual Russo & Steele Collector Car Auction held in Scottsdale, Ariz., ended late Sunday night, Jan. 20., with some jaw-dropping results. More
Categories: Auction News, Hobby News
Tags: Arizona auctions, auction, car auction, Mustang, russo and steele, Scottsdale
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The Two-Way
8:29 am
Sat August 31, 2013
Teen Gets Three Years In Gang Rape, Murder Of Indian Woman
Originally published on Sat August 31, 2013 1:43 pm
An Indian teen has been sentenced to three years in juvenile detention for the gang-rape of a 23-year-old woman who later died in the hospital, the first verdict in a case that has sparked international outrage over the brutal crime.
Police say the convicted 18-year-old was one of five men who lured the 23-year-old victim and her male friend onto a bus in the capital, New Delhi, where she was repeatedly raped and beaten in December.
"He has been convicted of rape and murder and sentenced to three years in a correctional home subject to review," Anil Sharma, the chief investigating officer in the case, said.
According to The Hindustan Times newspaper:
"The defendant, who was 17 at the time of the attack, has been sentenced to three years in a reform home, the maximum sentence he could have faced, his lawyer Rajesh Tewari said. Indian law forbids the publication of his name, though he has since turned 18."
"You may as well set the juvenile free, if the sentence is only three years for heinous offences like rape and murder," the victim's mother, who was in tears after the verdict, told reporters.
The Times of India says:
"The case against the juvenile offender had sparked a lot of public outrage with demands being raised to bring down the age to be declared juvenile from 18 to 16 years."
"The case was the highest profile of several similar incidents that have been reported in India in recent [months]."
We've reported on those other cases. Earlier this month, police made an arrest in the gang rape of a young photojournalist in Mumbai. In June, police arrested three men in connection with the rape of a U.S. tourist. The following month, six men were sentenced to life in prison in India after confessing to the gang rape of a Swiss tourist earlier this year.


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Date Taken: 1st September 2008. 1422 page views since 4th September 2008.
Swell Rating | Primary Swell | Secondary Swell | Wind (+ Gusts) | Weather | |||||||||
27ft | 14s | 233.73° | 24 mph | Rain | 51°f |
Francois Bouwer May 25, 2011 Rating: 0
Your alone, it's the biggest it has ever been, and you catch a wave. You surf it down the line, you reach impossibles, it pitches, it barrels, your in DEEP, you make it out, and you ride it on for another 1000 meters till you reach the beach, 2km from where you started...
philip Sep 5, 2008 Rating: 2
was this the swell that had the local crew frothing at the motuh when they saw the charts a week or two ago?


text:
I am starting to use Joomla!, and I just don't seem to "get it"
Am I the only one to find that it is really difficult to understand how to set things up? I've been working with it for about 10+ hours a week for nearly 6 months, and I'm STILL not understanding several things.
I'm mostly frustrated on the "menu items" vs "categories" vs "modules" etc.
The BIG issue (for me) is trying to figure out "what value/purpose" do 'categories' serve?
Anyone here experiencing the same?
Did any of you ever come up with an "A-HA!" moment?
Am I learning a 'dying' CMS?
(I realize most of this is the (nearly) complete lack of documentation available.)


text:
pele - 6:10 am on Jun 24, 2009 (gmt 0)
I don't understand why that would mess things up if they tell people to do those things. With the proxy error page coming up after each message you send to an editor they don't really give you much choice. Ten years ago one of the editors had added my site without me even applying to dmoz. I had to get another editor to move that into the category I wanted it to be in which took months since no editor for the category. Hoping this doesn't mess up my Google directory listing.
I followed the instructions that they put on their website. Contact higher up category editor if none exists with an explanation/request and to try resubmitting.


text:
You missed it This great deal for Synergy Paintball Challenge is over. But don't despair, we've got more great deals every day.
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Give your sharp shooting skills a lift with today's action-packed deal from Synergy Paintball Challenge in Grafton:
• $49 ($106 value) for a paintball package with admission and all-day air refills for two
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• Including a marker, mask, hopper, HPA tank, and 250 rounds of paintballs
• Paintball is safe and enjoyable for all ages as a unique and fun outing
• Tree-studded field features exciting obstacles
PAID VALUE EXPIRES ON June 29, 2018
PROMOTIONAL VALUE EXPIRES ON June 30, 2013
the fine print
- Limit one per person per visit
- Required to sign waiver
- Must be 10 years or older
- Reservations are required and subject to availability
- Merchant cancellation/re-scheduling policy of 7 Days applies; voucher subject to forfeiture
- Additional paintballs must be purchased at Synergy Paintball Challenge; outside paint prohibited
- Valid for admission on Saturdays 10:00 am to 4:00 pm and Sundays 11:00am-4:00pm
- Season runs through December 15, 2012 and will reopen in early March 2013
- Blackout days apply
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Synergy Paintball Challenge
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A collection of news and information related to Barry Bonds published by this site and its partners.
Top Barry Bonds Articles
Displaying items 56-66
Lloyd Waters: Baseball, apple pie and heroes
Story | Jan 27, 2013Back in the late 1950s and early '60s, the school ground in Dargan was the place to be if you wanted to play a little baseball. All the kids in the community would enjoy their summer vacations from school by playing the most popular sport.... -
A case for Tim Raines and Hall of Fame
Lance Armstrong, baseball's Hall and drug standards
Jeff Jacobs: Reign Delay - Nobody Gets In Hall This Year, And That's Good
Bonds, Clemens, don't deserve Hall of Fame honors
No players elected to Baseball Hall of Fame
Hall of Fame voters send clear message
Jim Palmer says HOF results are 'a shot across the bow of the whole Steroid Era'
Did baseball HOF voting surprise you?
Story | Jan 9, 2013 | 8:54 PMBonds, Clemens snubbed Dan Connolly Baltimore Sun It's not surprising that no one received the needed 75 percent of BBWAA ballots. It's also not surprising that Craig Biggio, he of the 3,060 career hits for the Astros, was the highest vote-getter... -
Some Hall of Fame thoughts from ESPN commentators
We're not perfect, but there is a way for writers to handle Hall of Fame controversy


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By EYJMUQUA
No photos have been taken in the prison planet.
not very good but great effort
no prison
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My Grandmother used to say you have one of everything you need, and maybe 2 of everything you Love. :)
This really never meant much to me. Now as an adult and mom of 3, soon be more, I have started decluttering and Get It. I have 4-5 diaper bags, each containing 1/5 of what I need at any given time. The kids have a few jackets for each season and because there are so many to keep track of, I can never find any. I needed a flashlight, and despite having about 30, none had batteries, and the ones that did I could not find. We were making a camp fire the other day, I knew we had a long lighter thing somewhere, didn;t know where, was at the store, so bought a 2 pack, then found the other later. Was unloading the dishwasher, couldn't fit the last 3 spatulas in the holder thing, before realizing that one of the was MIA.
I had this AHA of "why do I have so many of so many things that I will never use/need more than 1 of at a time?!?" Then Grandma's "one of" principle made sense. We have so many of so many things, usually a result of a rebuy of something when I could not find the others. ANd I can't find the others because they are so spread out because we have so much crap than none of it fits anywhere.
We are expecting #4 (and likely #5, according to 6 week sono).....I will then have a 13 yr old, 4 yr old, 1 yr old, and either 1 or 2 newborns. I REALLLLLLLY just want one of everything and I want to know where it is.
Anyone tend to live by the One Of way of thinking...either deliberately, of just by default?


text:
Magdalena in Vogue Russia May
Set in an art studio, Magdalena Frackowiak appears as if she could be a piece of artwork herself in "Mass Cult" by Tom Munro.
Magazine: Vogue Russia (May 2009)
Editorial: ????-????? (Mass Cult)
Photographer: Tom Munro
Models: Magdalena Frackowiak, Pernilla & Cameron
source | Tom Munro


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IT'S NICE ACTUALLY, i can dress myself ALBUM RELEASE 4.7.12
RSVP on facebook
- April 7th, 2012
- the Blue Macaw - 2565 Mission Street, San Francisco, CA 94110
- 9pm-2am / 21+
- $10
- $5 it's nice actually by i can dress myself
Absurd-dance-band i can dress myself, known for their blend of electroacoustic-funk, nerdcore rapping, flailing dance parties and abrupt costume changes is unleashing their debut album it's nice actually.
Come out of your winter hibernation and dress for visual stimulation and spring awakening: ruffled shirts, skirts, & bright-and-light colors just in time for Easter.
San Francisco's very own silly electroacoustic band produces face-melting dance beats with melodies both whimsical and a little creepy. Join Thundermouse, the Minister of Purpleganda and Graham as they warn you of alien invasions, get down with stegosaurus and leave you boneless. This unique and ecletic trio will freestyle, bow and blast you into the future where (spoiler alert!) there are also dinosaurs.
Underground Breaks
Funky Breaks
Slammin' Electro
Dynamic Electro House
Aggressive Progressive
Focusing on electronic dance music in the genres of house, electro, swing and funk. With over 10 years of experience as a dj, NeonBunny has played many of the great venues in the Bay Area. From De Young Museum to the Sound Factory, and even occasionally known to throw down at a dive bar called the Stud. And as music director for the former Bunny Jam parties, NeonBunny formed his connections with the creative, art, and Burning Man communities, while learning to add humor and creativity to his dj sets.
Decor will be provided by Bottlecap Gazebo, an art project for Burning Man 2012. Design by San Francisco artists Max Poynton and Andrew Grinberg. Constructed by Elephant Bird Camp.
Dearest Funky Ones,
You are invited to our third annual Funky Ones Holiday party!
Where: Castle McLeodister
When: The evening of Saturday December 17th. 9p-late
Our yearly holiday party celebrates our community and it's accomplishments throughout the year. 2011 has been exceptionally triumphant and this year we present the 'Host of House Parties Present' in honor of our distinguished friends who have made this year so marvelous. While we intend the party to be relatively small, we encourage you to include close friends and fresh faces that would be most delighted by our unique happenings.
The legendary bed stage will be returning with musical acts all night. David Colón will begin the evening by regaling us with acoustic holiday favorites, a midnight performance by i can dress myself will follow and the night will close with a delicious and epic dance party DJ'd by Dioscuri.
We will be serving beer and holiday tea, although gifts of spirits and ales are encouraged. As usual, outfits of the freshest holiday garb are smiled upon.
Thank you all so much for collaborating on all our magical adventures!
Eamon and Graham
BUY TICKETS RSVP on facebook
- November 26th, 2011
- Red Devil Lounge - 1655 Polk St # 1 San Francisco, CA 94109-8820
- 8pm-1am / 21+
- $10 (presale)
Come experience a veritable feast of funk and freakishness featuring:
Planet Booty is a force to be reckoned with. Having started as a genre-defying concept album by brothers Nathan and Dylan Germick that blends electropop, sci-fi synths, space funk and booty bass, the project has evolved into a live show of epic proportions. The 6-piece ensemble fuses electronics, drums, percussion, horns, marimba, guitars, and soulful singing (with a splash of choreography and theatrics) to create a hyper-charged and highly entertaining dance party experience.
San Francisco's very own silly electroacoustic band produces face-melting dance beats with melodies both whimsical and a little creepy. Join Thundermouse, the Minister of Purpleganda and Graham as they warn you of alien invasions, get down with stegosaurus and leave you boneless. This unique and ecletic trio will freestyle, bow and blast you into the future where (spoiler alert!) there are also dinosaurs.
BREAKIOSAURUS 8.12.11 - RSVP on facebook
The Elephant Bird Camp* Fundraiser
- August 12th, 2011
- The Blue Macaw - 2565 Mission St. San Francisco, CA
- 9pm-2am / 21+
- $5 before 11pm/$10 after
- $6 Jurassic Juice and $3 Sex Pixel Shots
Hip-Hop into our time machine and get fresh in your illest Breakin/Dinosaur outfit and join San Francisco's Premier Costume Party Proprietors for some Jurassic Malarky!
Featuring performances by:
San Francisco's very own silly electroacoustic band produces face-melting dance beats with melodies both whimsical and a little creepy. Join Thundermouse, the Minister of Purpleganda and Graham as they warn you of alien invasions, get down with stegosaurus and leave you boneless. This unique and ecletic trio will freestyle, bow and blast you into the future where (spoiler alert!) there are also dinosaurs.
San Francisco based, forward thinking DJs/Producers - Sólfire & BTRU joined forces in 2011 w/ Miss Minxx (official VJ) to bring a unique audio visual club experience.
From a dark alternate future space reality (We THINK), their purpose here and now on PlanetEartZ is unknown, (Likely: breeding/takeover). They eat VHS tapes and write dance music. Their dark, electro-funk songs are bio-genetically engineered to cause listeners' bodies to immediately disrespect themselves. Starbeast II. In 3D.
Kraft Funk
With a tip of his hat to hip hop's origin, producer Josef Allen explains Kraft Funk as a DJ set comprised of early '80s electronic music pioneers Kraftwerk songs mixed with '70s - current era funk breaks. A montage of grooving quirky electro-funk performed by triggering multiple layers of samples, loops, and songs.
* Elephant Bird Camp is the Funky Ones' on-Playa manifestation located on D at 7:30. Explore live music, open jams, a pastie making workshop, and Grahama's House, a Mutant Vehicle version of a suburban home complete with a stern but forgiving grandmother.
You have been selectively invited to The Funky Ones Freakeasy. Only the best dolls, debs and daddy's have been invited, so put on a skirt that'll show off those gams and get ready to swing. This party is not for everyone, but it definitely is for you…
10:00 i can dress myself (live drum set)
11:15 Zinc Finger in the Major Groove
With special guest performances by Max Stiers, Paul McCollister, Belly Button Lovin', and Mama Queso's Burlesque Show.
Come early, the place is small and the doors will close when capacity is reached.
Cover $7. Guests will only be admitted if they have the password. The password will be given the day before the event via FB email. So RSVP to receive the word…
Comrades! The days of oppression are over. The Funky Ones Worker's Party has come to free you of the capitalist shackles of non-funktitude and uninspired apparel. Led by the Minister of Purpleganda, the Great Red Army and Graham; The Funky Ones Worker's Party will lead all of humanity to the new state of righteousness. A state where funkiness prevails and all are entitled to disco dance moves, get fresh beats and Hansen's soda. To reign in this new era in the STATE OF FUNK, we present to you musical acts meant to show our GREAT UNITY OF FUNKINESS!
Great leaders of the Proletariat:
i can dress myself
The world's 3rd best Top Gun original motion picture soundtrack cover band:
The Top Gunz
No cover. However, this is an Elephant Bird Camp art car fundraiser, so donations are highly encouraged.
Glory to the Great February! The question remains, ARE YOU READY TO SURRENDER TO FUNK!?
You are invited to a vintage return to the house parties of Christmas Past, a signature celebration by the Funky Ones featuring live music from i can dress myself, Friday, December 10th at Castle McLeodister on San Francisco's Haight St.
Check our more holiday gifs here
Video by Rachel Dusa, Kollin Holtz and i can dress myself
Saturday, July 17th, 2010
LiPo Lounge
916 Grant Avenue, San Francisco
$5 / 21+
http://www.thefunkyones.co m/
♫♪ ♫♪♪ ♫♪ ♫ ♫♪ ♫♪ ♫♪♪ ♫♪ ♫ ♫♪ ♫♪ ♫♪♪ ♫♪ ♫ ♫♪ ♫♪ ♫♪♪ ♫♪ ♫ ♫♪
Step Right Up!
Your Agents and Operators, THE FUNKY ONES
Lovingly Invite you to a CARNY PARTY!
For Just a fin ($5)
You! Sir or Madame are entitled to
A Night of Adventure featuring:
i can dress myself
D!sco Mike and DJ BTru of SF NIGHTS
Come on Larry, don't be a HAMMER-SQUASH!
Come On Down to the LiPo Lounge,
that Plush Possum Belly Located right down in China Town
SATURDAY JULY 17th!
Sweet Whisky Pie! Are you With IT!?!?
Prepare yourself to experience the outer limits of the funkosphere… and beyond!
On May 29th of the year 2010, Starship MILK will set off in search of the elusive Elephant Bird.* On this intersteller odyssey a rag tag crew of enhanced humanoids, space monsters and mercantile robots will create the perfect hybrid of booty-shaking bar show and face-melting house party. All crew members will be treated to mind-bending performances and unspeakable delights by premium bands live from the future:
♪♫•*¨*•.¸¸ featuring ¸¸.•*¨*•♫♪
i can dress myself
Kiss & Tell
¸¸.•*¨*•♫♪.¸¸with¸¸.•*¨*•♫ ♪.¸¸
The George Lacson Project
Special DJ guests The SF Nights
Guided by wise space captains, the most noble and courageous crew may travel all the way to the legendary Planet McLeodister encircled by rings of pure funk and rumored to be the nesting grounds of the mighty Elephant Bird.*
AN EVENING IN DEEP SPACE by the Funky Ones
ELEPHANT BIRD Burning Man Camp Fundraiser Party
Saturday, May 29th @ Milk Bar on Upper Haight.
21+ doors at 8 pm | $8/$6 before 10 pm
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*Elephant Bird is the name of a music and sound camp that the Funky Ones are creating for Burning Man 2010. We will build a full, portable sound stage, equipped with instruments, microphones, PA system, and lights. In the desert, the stage and instruments will be open for musicians of all types to play and jam with each other. We hope to encourage collaboration among musicians and the creation of diverse and dynamic music for all to enjoy!


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50 experts and 171 advocates oppose the HHS/IOM Contract to re-define ME/CFS.
Check out our IOM Contract Forum for the latest news and to join the campaign.
Andrew Gladman takes a brief look at what cytokines are and how they might relate to our disease - exploring some of the research that is indicating their involvement in disease pathways...
Discuss the article on the Forums.
New WPI and CDC XMRV sequences in genbank
Discussion in 'XMRV Research and Replication Studies' started by Bob, May 17, 2011.
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Page 4 of 11


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Theater Review: Kissing the Hand of Frank Langella, in King Lear
It snaps into focus whenever he's onstage.
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Skip to content, or skip to search.
It snaps into focus whenever he's onstage.
Frank Langella stars in this tale about an elderly ex–jewel thief and his robot assistant.
Terence Rattigan's 1963 drama of global financial (and family) tension.
The movie is lean and fast and endlessly upending, and unlike most modern crash-and-bash films, you can actually follow the car chases and fisticuffs.
No whammies, no whammies, no whammies, stop!
Frank Langella may have won a Tony for playing Nixon onstage, but that doesn't mean the blogosphere is happy about his casting in the film version.
Plus: After years of ignoring its most teen-friendly and overall awesome comics title, Marvel has finally decided to bring 'Runaways' to the big screen.