text:
Dual Roles for Rac2 in Neutrophil Motility and Active Retention in Zebrafish Hematopoietic Tissue Developmental Cell, Volume 21, Issue 4, 18 October 2011, Pages 735-745 Qing Deng, Sa Kan Yoo, Peter J. Cavnar, Julie M. Green and Anna Huttenlocher Summary Neutrophil homeostasis is essential for host defense. Here we identify dual roles for Rac2 during neutrophil homeostasis using a zebrafish model of primary immune deficiency induced by the human inhibitory Rac2D57N mutation in neutrophils. Noninvasive live imaging of Rac2 morphants or Rac2D57N zebrafish larvae demonstrates an essential role for Rac2 in regulating 3D motility and the polarization of F-actin dynamics and PI(3)K signaling in vivo. Tracking of photolabeled Rac2-deficient neutrophils from hematopoietic tissue also shows increased mobilization into the circulation, indicating that neutrophil mobilization does not require traditionally defined cell motility. Moreover, excessive neutrophil retention in hematopoietic tissue resulting from a constitutively active CXCR4 mutation in zebrafish warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is partially rescued by the inhibitory Rac2 mutation. These findings reveal that Rac2 signaling is necessary for both neutrophil 3D motility and CXCR4-mediated neutrophil retention in hematopoietic tissue, thereby limiting neutrophil mobilization, a critical first step in the innate immune response. Summary | Full Text | PDF (1535 kb) |
Pattern recognition receptor function in neutrophils Trends in Immunology, Volume 34, Issue 7, 1 July 2013, Pages 317-328 Christina J. Thomas and Kate Schroder Abstract Previously, neutrophils were largely ignored in the pattern recognition receptor (PRR) signaling field. However, interest in neutrophil biology has been revitalized by emerging roles for neutrophils in promoting protective and pathogenic T helper (Th)17-driven immune responses and in orchestrating innate and adaptive immunity via cytokine/chemokine production. Although it was originally assumed that neutrophils are transcriptionally inert and their short lifespan limits their ability to respond to PRR agonists, the past 5 years has seen tremendous advances in neutrophil PRR signaling that have shifted this paradigm. Here, we review recent findings that demonstrate that neutrophils express a broad repertoire of PRRs, respond dynamically to their stimulation during infection and inflammation, and that neutrophil PRRs are key regulators of in vivo host immune responses. Abstract | Full Text | PDF (632 kb) |
Biomechanics of P-Selectin PSGL-1 Bonds: Shear Threshold and Integrin-Independent Cell Adhesion Biophysical Journal, Volume 90, Issue 6, 15 March 2006, Pages 2221-2234 Zhihua Xiao, Harry L. Goldsmith, Fiona A. McIntosh, Harish Shankaran and Sriram Neelamegham Abstract Platelet-leukocyte adhesion may contribute to thrombosis and inflammation. We examined the heterotypic interaction between unactivated neutrophils and either thrombin receptor activating peptide (TRAP)-stimulated platelets or P-selectin-bearing beads (Ps-beads) in suspension. Cone-plate viscometers were used to apply controlled shear rates from 14 to 3000/s. Platelet-neutrophil and bead-neutrophil adhesion analysis was performed using both flow cytometry and high-speed videomicroscopy. We observed that although blocking antibodies against either P-selectin or P-selectin glycoprotein ligand-1 (PSGL-1) alone inhibited platelet-neutrophil adhesion by ∼60% at 140/s, these reagents completely blocked adhesion at 3000/s. Anti-Mac-1 alone did not alter platelet-neutrophil adhesion rates at any shear rate, though in synergy with selectin antagonists it abrogated cell binding. Unstimulated neutrophils avidly bound Ps-beads and activated platelets in an integrin-independent manner, suggesting that purely selectin-dependent cell adhesion is possible. In support of this, antagonists against P-selectin or PSGL-1 caused dissociation of previously formed platelet-neutrophil and Ps-bead neutrophil aggregates under shear in a variety of experimental systems, including in assays performed with whole blood. In studies where medium viscosity and shear rate were varied, a shear threshold for P-selectin PSGL-1 binding was also noted at shear rates <100/s when Ps-beads collided with isolated neutrophils. Results are discussed in light of biophysical computations that characterize the collision between unequal-size particles in linear shear flow. Overall, our studies reveal an integrin-independent regime for cell adhesion and weak shear threshold for P-selectin PSGL-1 interactions that may be physiologically relevant. Abstract | Full Text | PDF (270 kb) |
Copyright © 1994 The Biophysical Society All rights reserved.
Biophysical Journal, Volume 67, Issue 6, 2535-2545, 1 December 1994
Research Article
R.S. Hartman, K. Lau, W. Chou and T.D. Coates
The search for a fundamental mechano-chemical process that results in net cell motion has led investigators to fit neutrophil tracking data to well described physical models in hopes of understanding the functional form of the driving force. The Ornstein-Uhlenbeck (OU) equation for mean square displacement describes a locally persistent and globally random process and is often used as a starting point for analysis of neutrophil displacements. Based upon the apparently close fit of neutrophil tracking data to this equation and the nature of its derivation, biologists have inferred that the motor of the neutrophil is best represented as a random process. However, 24 of 37 neutrophil paths that we investigated preferentially display programmatic rather than Markov short term correlations between displacements or turn angles. These correlations reflect a bimodal rather than a uniform distribution of subpath correlations in the two variables, and are strongly sampling rate-dependent. Significant periodic components of neutrophil shape change are also detected at the same time scale using either Fourier or elliptical Fourier transform-based descriptors of the neutrophil perimeter. Oscillations in neutrophil velocity have the same period. Taken together, these data suggest a nonstochastic, and perhaps periodic, component to the process driving neutrophil movement.


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calling people garbage is a shitty thing to do. You just said something mean spirited without also saying anything interesting or constructive so people clicked a thumbs down icon a few times. "Tolerated" is way too strong of a word. It implies people had an actual reaction beyond clicking an icon of a thumb pointed down.
This is a Damned cover. It's definitely great though, certainly better than the original*.
* the original has saxophone
"Set The Ray to Jerry" from this release but in general "galapagos"
sorry i thought those would be just links if i posted URLs. I am a terrible person
this album cover is fantastic. It's like when a movie trailer doesn't give away the whole film. I have so many questions. What is that green sludge the baby is eating? Is the mosquito attacking the baby because of the sludge or did it get the jump on the baby because the baby was busy with the green sludge and didn't notice the baby sized mosquito?! The sludge is labeled YYY's so it's obviously important! At first I thought maybe there was some kind of static shock going on because of the baby's hair but it looks like there is either a fan off to the right of the image or more likely the left of the image is down relative to the action because some of the YYY's green sludge is leaking out in the same direction the baby's hair is falling, if that is true is this a mid-air battle?!
I have. Is that is a reference to BV that i am not getting?
Yes! and I was worried it would get a little brooklyn vegan-y without the voting system
you could google "where did the downvote button go?" but it probably wouldn't get any hits. I just googled "sigur ros live" and got NOTHING so don't bother trying that one either
really relatable lyrics about relationships and concise pop song structures
it's probably because Morrissey is fucking amazing
Runner is amazing
In the context of a postal service song coming out of ben gibbard's mouth that could mean something as gentle as kissing for an hour and then not getting a full 8 hours sleep.
Is this a new new song or a song or something left over from 10 years ago that is new to us?
It's insane to assume that
Well I can appreciate being in a dark place and I certainly don't mind you cursing at me if that is what you want to do or if that helps you in some way, though I am not trying to attack you I just felt like it was possible you were projecting some insecurities you might have about the relationship of drugs & music in your first comment because no one was saying that people who don't take drugs can't appreciate the music at the same level of someone who does but it seemed like that was maybe what you got from it.
It would be like a group of people watching a movie and eating popcorn and drinking soda and one of them comments on how much fun the experience of snacks and a movie is, that doesn't mean that if you are not into popcorn you can't watch and love the movie. Statements like that are purely subjective.
"I don't mean to sound preachy, but I wasn't aware drugs were a prerequisite to enjoy music in the first place"
I have seen (i am assuming) most of the same reviews that you have and while they reference drugs they never once imply that taking them is a prerequisite to enjoy it". The period of time where most humans fall in love with music is around the same time some experiment with drugs and so for many people there is a link between the two but no one is saying they appreciate music or albums more for having taken drugs. Don't let yourself feel so attacked/insecure.
Though you should know that if you take LSD you absolutely do experience music differently than when you are sober. Better/worse is kind of pointless to argue because it's 100% subjective but you should know that it's DEFINITELY different.
I don't think you are allowed to say that you are not judging someone and then say that you no longer respect that person for the same action you claim not to pass judgement on
they are a trio
Well it was a joke about feeling old. No one on this thread has said anything snarky. No one is not thrilled about the news of this album
"soft as snow but warm inside" as a tramp stamp is probably funnier. I shouldn't have rushed
I wasn't double digits but I was alive and pretty deep into Creation Recs at that time. I got the pygmalion album cover tattoo'd on my calf when i turned 9.
this sentence ruined my night. Every MBV album has been released in my lifetime.
This is a different order than I would have picked!!!
It's as close to a number as a symbol can be except for a lower case L

subset: commoncrawl


text:
Newest Review: ... easily (which last a VERY long time without stopping), and this time on Aeroflot, my sister was unfortunate in getting a big one.... more
Please Never Again
Author Name: bon
Date: 19/11/07
Advantages: Cheap
Disadvantages: The worst ever
Do not even consider flying with Aeroflot. There are as bad as they have always been, & as mentioned on this site. Yes, they can be fine if all goes to plan but when it does go wrong you enter a world of pain. I was last with them November 2007 & the staff are just the worst. Not one person will help, there is no process to assist you when flights are cancelled or baggage goes missing, which happens often & has happened to me. The planes are very shabby if flying within Russia & their record for safety is the worst.
It seems their staff are hell bent on annoying you with the most atrocious service you can imagine. I asked staff at Moscow to assist me with finding my luggage they just told me to go else where, when I pushed them to help me they just walked off, an experience I have had before with Aeroflot. It is like entering some parallel universe, where everything works in reverse, where sanity ran away screaming & left the lunatics running the asylum. Pay the extra money, fly with another airline.
Summary: Dont Use Them


text:
Definition of Krebs cycle in English:
Krebs cycle
Line breaks: Krebs cyclePronunciation: /krɛbz
Biochemistry- The sequence of reactions by which most living cells generate energy during the process of aerobic respiration. It takes place in the mitochondria, using up oxygen and producing carbon dioxide and water as waste products, and ADP is converted to energy-rich ATP.More example sentences
- For instance, Nelson at one point referred to a scientific paper on the evolution of the Krebs cycle.
- The Krebs cycle is part of the energy pathway in all living cells.
- Overall, the Krebs cycle provides energy and heat for the body's many processes, and the mitochondria are key to this process.
1940s: named after Sir Hans A. Krebs (1900–81), German-born British biochemist.


text:
User Review: Deuter Freerider Pro 30
Price Paid: $148.95
I'm using this back as my go to daypack. I've had it out on some snowshoe, backcountry nordic skiing and just hiking. At one point I had snowshoes on the back and cross country skis on the side. It's large enough for a winter day hike and I'm hoping compressible enough for summer.
One of the cool things about it is you can get to the main compartment even with lets say skis, snowshoes, poles, and a tripod strapped to it. There are two zippers in to the main compartment one runs around the suspension so you don't have to undo any straps holding stuff on the outside the pack. It has a lot of straps making very versatile.
And it's tough its built but that makes it a bit heavy it's 3 lb 15 oz.
- Versatility
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- Look good
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found 2 items where the city is Steele and the state is Alabama. Showing page 1 of 1. |
search: |
St. Clair County School System. Steele Junior High School. ( Steele, Alabama United States) St. Clair County, AL. Steele Public Library. ( Steele, Alabama United States) [web site ] [Infocentre] |
About lib-web-catslib-web-cats (library web sites and catalogs) is a free directory of libraries throughout the world. This directory is a component of Library Technology Guides. Please contact Marshall Breeding if you have any corrections or concerns about this resource. |


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Rating: Hollis 7 pocket diving weight belt. 4/1/2013 I like the belt and the fact that you can carry all the weight you need. I find that they should have left spacing or added loops for attaching suspenders. I cannot keep the belt up without them. I have added a pair of suspenders but do to no spacing of pockets they tend to bunch the pockets and twist the loop on the suspenders. Was this review helpful? Yes No
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Rating: Henderson Farmer John Wetsuit. 2/28/2013 I love the ease of entering and exiting this suit. The elasticity of the material is far better than i expected making the suit very comfortable to wear. The only drawback i can see is they do not offer 4x for the more portly divers and i am borderline on 3x to 4x. The suit is well built for its cost and i would recommend it to anyone under 4x in size. Chuck Raison Was this review helpful? Yes No Product Information Questions? Contact our certified instructors E-mail our instructors at firstname.lastname@example.com
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This here page is that of
, whose name is in bold for... some reason.
A 14 year old fanartist from Poundland Town St. Helens, I also write for Sonic Wrecks, and am an avid collector of video game merch in general. That said, for a merch collector I don't do a particularly good job at it.
You can find me on
over at
and you can find me on
Also of note is I'm a huge SEGA fanatic, particularly around the SEGA Saturn era, but I'm also a fan of SEGA's arcade history and the good old SEGA Mega Drive.
So, I recently replayed Super Mario World
on 05.09.2013
As much as I try to stray from admitting it, I've got to say-my Wii U has become less of a video game console as of late, and has instead been relegated to a dust magnet sat next to my other consoles. In a sense, it's quite depressing to open up my 'gaming cabinet' and see the poor system having gathered so much dust, then looking directly to it's left and seeing a spotless SEGA Saturn. It perhaps says something when I'm treating a system released in 1995 better than a brand new, £300+ system with the 'latest technology.'
Though that's not to say I dislike the Wii U-there's a reason I got it, after all. It's a lovely system, and it's certainly an improved situation since Day 1. Recently, the Rayman Legends Challenge App was released, and so I decided it was time to dust off the GamePad and actually play the system I, and many others, blew the aforementioned £300+ on.
Whilst going to actually download the app, I realised the Wii U Virtual Console had finally been set up as well. At first, I was relatively unimpressed. The launch line-up didn't seem to stellar, and for NES games particularly, the prices seemed rather off. Thankfully, one game was on offer, and that game just so happened to be Super Mario World.
My first experience with Super Mario World was with the Game Boy Advance port
Super Mario Advance 2
, which was, to say the least, a lovingly crafted port. It wasn't a poor emulation of the original, and though certain aspects had to be reduced for understandable reasons (the aspect ratio and the sound come to mind), the game still had the tight controls, crisp graphics, and overall fantastic experience that the original had. Hell, Super Mario Advance 2 is hands down my favourite Game Boy Advance game, and I played it to the point I reached the maximum amount of lives obtainable and to the point the scoreboard wouldn't increase any further. And I enjoyed every second of it.
I slaved over this version of the game for a good 5 or 6 years. I got it when I was about 7 or so, and yet only got all 96 exits when I was about 10. Suffice to say, over the entire course of the game, I felt my skill level as a gamer progress, and the satisfaction I got from finally completing the Special World all those years later was one of utter triumph. It was the sort of thing I'd jump around the house about with excitement-and as such, for the incredible experience the game provided, it went without saying it was an unforgettable game for me.
The Wii Virtual Console provided my first experience with the SNES original. Whilst I enjoyed playing through the game once again, it didn't hold the same feeling as
Super Mario Advance 2.
I never gained the motivation to get all 96 exits again, despite it really not being too great a task, and it lacked the wonder of the GBA version, and the imagination it inspired, in my eyes. Maybe it was just because I'd played the game before, maybe it was because I wasn't playing it on a handheld, maybe it was some other poor reason. In addition, once I defeated Bowser I never went back to it, because I didn't realise the final castle isn't counted as one of the 96 exits, and so the game just stops. I honestly thought the game was frozen, and I didn't wish to reset in case I lost any progress. I was a daft kid, suffice to say.
The next time me and Super Mario World's paths crossed was in a Let's Play. Given how much I loved
Advance 2
, it seemed fair I should go through the game to try and get my Youtube channel off to a nice start. Thing is, this was in the rather early days of my Youtube channel-I was a novice to Let's Plays, so after editing I never bothered checking the rendering, meaning lovely black screens populated the videos. In addition, a nightmarish banner to the left populated each video, looking like something a 5 year old threw up on MS Paint. In addition, once again the playthrough didn't feel as fun as the GBA version-notably, I knew now I could potentially have an audience, and I feel I shifted my play style to try and 'fit' that. The game still wasn't a bad game, hell no-and I had a good deal of fun. But it still didn't quite provide the wonderful experience I'd been fortunate to have all those years ago.
This all brings me to my most recent playthrough of this game, on the Wii U. Out of all of the versions of the game I've played, this one was perhaps the one I've enjoyed the most. It felt like the wonderful handheld experience that
Advance 2
provided, thanks to the GamePad, but in addition it felt like the version that got the most things right. The wonderful HD presentation makes the sprites look crisper than I ever expected, and the sound has also received a boost, though with this level of hardware compared to the Game Boy Advance, and hell, the Wii, that's a given. Also, now I knew the specific differences between the versions, notably
to worry when the ending screen appeared to freeze, gave me the motivation to do what I intended to on the Wii-get those exits.
What took me about 5 years or so on the Game Boy Advance took me a rather nice 3 days to recreate on Wii U. For me, the Wii U version IS the definitive way to play this game now, and suffice to say I'm already halfway through my second 100% run of this beauty.
Super Mario World and I may not go back as far as the gamers who originally slapped the game into their NES in 1992 and sat down for some 16-Bit Mario action, but to say it's memorable to me is an understatement.
It is true that at heart, I'm a SEGA guy through and through. SEGA makes up the vast majority of my childhood, and I wouldn't swap that for the world. But it goes without saying, that Super Mario World is easily my favourite game from the SNES, and perhaps even my favourite game of all time-at the least, it's certainly in the top 3.
So hey. Thanks Nintendo. Super Mario World inspired me as a kid. It helped move along my creativity, and presented a vast world full of secrets that felt so intriguing and mysterious to a 7 year old sat playing a small handheld system.
And perhaps most of all, it was damn fun. And it is to this day.


text:
'Go to hell Barack' ad must be removed, Moran tells WMATA
Rep. Jim Moran (D-Va.) is calling for the removal of an ad at an Orange Line Metro station that he says blatantly offends President Barack Obama.
In a letter to WMATA General Manager Richard Sarles, Moran asks for the removal of an ad at the Clarendon Metro station that says, "Go to hell Barack."
The ad is tied to the controversy over the health care overhaul.
"This ad is deeply disrespectful of the President of the United States and does not belong in the Washington Metropolitan Area Transit Authority network," Moran said in the letter.
The Democratic congressman then went on to say that while he understands that WMATA should display ads, even those that are political, "minimum standards of decency must be maintained through a vetting process."
"I assume such a process exists, but surely this ad does not meet those standards," Moran said. "It's not about politics, it's about appropriateness."
Others likewise found the ad in poor taste.
"It is very disrespectful. You can find other ways to do it more politely," said rider Shanelle Dorham.
"I wish they would say who actually put the ad up. Put your name on it," said rider Rich Hinman.
The ad calls on readers to purchase "Sick and Sicker," a documentary produced by Logan Darrow Clements who believes the president's reforms will hurt, not help, Americans.
However, a Metro spokesperson said the ad can't be taken down because the message is protected political speech. In a statement from the transit agency:
WMATA advertising has been ruled by the courts as a public forum protected by the First Amendment of the Constitution, and we may not decline ads based on their political content.
Read the full text of Moran's letter here:
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text:
Find Acupuncturists, Massage Therapists
Browse Search How to get listed? |
Ryan Altman |
Map Location L.Ac. / Executive Director Adams Avenue Integrative Health 3239 Adams Ave. Normal Heights San Diego CA 92116 USA Website Email: firstname.lastname@example.com Phone: 619-546-4806 Specialty: Japanese Classical Acupuncture, TCM, Community Outreach, Community Style Acupuncture, Integrative Healthcare Languages Spoken: English, German, Some Spanish, Some French Campus Attended:
Program Attended:
Year of graduation: 2005 Ryan is the Founder and Executive Director of the Alternative Healing Network, a 501(c)(3) non-profit that promotes the use of integrative healing to the public and improves access to care. While studying Chinese Medicine at Pacific College of Oriental Medicine, Ryan created the San Diego Healing Arts Festival, a free community event that brings music and healing together, allowing a fun and accessible forum to teach the public about integrative health care. Later he worked to bring these healing techniques directly to the under-served communities who needed it the most. With the help of a growing team of volunteer practitioners and affiliations with Pacific College, Concorde Career College, IPSB, and UCSD – School of Medicine, he created a series of "Integrative Health Nights" at local community centers to offer free "integrative" health services to the under-served community. In June 2008, Ryan selected his team of practitioners and created Adams Avenue Integrative Health (AAIH). As a project of the Alternative Healing Network, AAIH is a community oriented integrative health center that operates on a sliding scale to make integrative health services available and affordable to everyone. The proceeds from AAIH go to support the free Integrative Health Nights. Additionally, Ryan is a graduate of the Pacific College of Oriental Medicine. He practices a combination of Classical Japanese acupuncture with Reiki, offering gentle, energetic treatments that follow meridian theory while using lighter gauge needles and a shallow insertion. This is good for anyone who may be a bit more needle sensitive. Ryan also incorporates "tui na", a Chinese therapeutic massage technique, and "moxabustion" or heated herb therapy into most treatments. |
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Festivals In Brief: Team Clermont, Camp Bestival, Shine a Light, Respect Jamaica Reggae
By Evan Minsker on July 3, 2012 at 07:32 p.m.
WHAT: Team Clermont Summer Showcase & Prom
WHEN: July 26-27
WHERE: Athens, GA
WHO: Bear in Heaven, the Olivia Tremor Control, Dent May, Crooked Fingers, Pattern Is Movement, moreWHAT: Camp Bestival
WHEN: July 26-29
WHERE: Dorset, England
WHO: Happy Mondays, Hot Chip, Frankie Rose, Totally Enormous Extinct Dinosaurs, Little Dragon, Jimmy Cliff, Chic ft. Nile Rodgers, the 2 Bears, 2:54, moreWHAT: Shine a Light Music Festival
WHEN: July 21
WHERE: Wantagh, NY
WHO: The War on Drugs, Dean & Britta, moreWHAT: Jamaica 50 Festival
WHEN: July 25 - August 6
WHERE: London, England
WHO: Lee Scratch Perry, Damian Jr. Gong Marley with Stephen and Julian Marley, Toots & the Maytals, Jimmy Cliff, U-Roy, Junior Murvin, more -
News in Brief: Chairlift/Rewards, Release the Sunbird, Fair Ohs, Teen Daze, Camp Bestival
By Larry Fitzmaurice on July 21, 2011 at 04:40 p.m.
-- Brooklyn synth-pop outfit Chairlift will release a new single on Terrible Records August 16. Listen to the A-side "Amanaemonesia" at Forkcast. Former member Aaron Pfenning's project Rewards will release the "Equal Dreams" single July 25 on DFA. The title track features vocals from Solange Knowles. Listen to it here.
-- Rogue Wave's Zach Rogue has a new side outfit, Release the Sunbird; their debut LP, Come Back to Us, is out July 26 on Brushfire. Stream the whole album at NPR.
-- A few new releases from indie label Lefse: UK tropical-popsters Fair Ohs will put out their new LP Everything Is Dancing on July 26, while Canadian chillwave man Teen Daze's A Silent Planet is out on CD and cassette September 13 on sub-label Waaga. Head here to check out Fair Ohs' "Summer Lake", and head here to hear Teen Daze's "The Harvest".
-- Camp Bestival goes down July 28-31 in Dorset, England. Primal Scream, Blondie, Mark Ronson and the Business Intl., Laura Marling, ABC, Katy B, Ms. Dynamite, and others are among those scheduled to perform.
Festivals in Brief: Camp Bestival, Kendal Calling, Field Day, Wicker Park Fest
By Tom Breihan on July 15, 2010 at 02:15 p.m.
WHAT: Camp Bestival
WHEN: July 30 - August 1
WHERE: Dorset, England
WHO: The Fall, Lee "Scratch" Perry, Joker, Joy Orbison, Friendly Fires, the Human League, George Clinton & Parliament Funkadelic, Madness, Marc Almond, Gold Panda, Field Music, Pete and the Pirates, Ragga Twins, Tony da Gatorra Vs. Gruff RhysWHAT: Kendal Calling
WHEN: July 30 - August 1
WHERE: Cumbria, England
WHO: Doves, Wild Beasts, the Futureheads, These New Puritans, British Sea Power, Badly Drawn Boy, First Aid Kit, Erol AlkanWHAT: Field Day Festival
WHEN: July 31
WHERE: London, England
WHO: Phoenix, Caribou, Atlas Sound, No Age, the Fall, Mouse on Mars, These New Puritans, Memory Tapes, Joker and Nomad, Dam-Funk and Master Blaster, Pantha Du Prince, Matthew Herbert, Ramadanman, Simian Mobile Disco, the Golden Filter, Chilly Gonzalez, Moderat, Gold Panda, Mount Kimbie, Steve Mason, Gruff Rhys Vs. Tony Da Gatorra, Max Tundra, Silver Apples, Dam MantleWHAT: Wicker Park Fest
WHEN: July 31 - August 1
WHERE: Chicago, IL
WHO: Holy Fuck, Cap'n Jazz, Torche, Baroness, Plants and Animals, Yakuza Arkestra, the Gaslamp Killer, Scotland Yard Gospel Choir, the Hood Internet, Happy Birthday -
Festivals in Brief: Camp Bisco, Camp Bestival, Indietracks, Splendour in the Grass
By Tom Breihan on June 1, 2009 at 02:50 p.m.
A quick rundown of upcoming music festivals around the world:
What: Camp Bisco
When: July 16-18
Where: Mariaville, NY
Who: Nas and Damian Marley, Special Disco Version, Chromeo, Kid Cudi, the Orb, Dr. Dog, Flying Lotus, Holy Ghost
What: Camp Bestival
When: July 26-26
Where: Dorset, England
Who: PJ Harvey, Mercury Rev, Bon Iver, Phoenix, Chic, Aeroplane, Micachu, Roots Manuva, Tinchy Stryder, Florence and the Machine
What: Indietracks
When: July 24-26
Where: Derbyshire, England
Who: Camera Obscura, Emmy the Great, Au Revoir Simone, Lucky Soul, BMX Bandits, Rose Elinor Dougall, Tender Trap
What: Splendour in the Grass
When: July 25-26
Where: Byron Bay, Australia
Who: Bloc Party, the Flaming Lips, MGMT, Jane's Addiction, the Specials, Midnight Juggernauts, Friendly Fires, White Lies, the Gutter Twins
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Article Information
Related Articles
- Genealogy of the Anterior Pituitary Gland: Tracing a Family Tree
Genealogy of the Anterior Pituitary Gland: Tracing a Family Tree
Trends in Endocrinology & Metabolism, Volume 10, Issue 9, 1 November 1999, Pages 343-352
Heather L Burrows, Kristin R Douglas, Audrey F Seasholtz and Sally A Camper
AbstractThe anterior lobe of the pituitary gland is derived from the oral ectoderm early in gestation. A variety of techniques have been used to understand how early precursor cells differentiate to form the five major cell types that populate the adult anterior lobe. Current evidence suggests that corticotropes arise from a lineage distinct from that of the other four cell types. The cells of the other lineage branch – thyrotropes, gonadotropes, somatotropes and lactotropes – appear to be related because of their dependence on common transcription factors and the frequent occurrence of cells that produce multiple hormones. While thyrotropes arise through two routes, the lineage related to somatotropes and lactotropes appears to be the most important for hormone production. Each cell type can populate the organ and function in the absence of the other cell types, except for lactotropes, which have a strong dependence on somatotropes. Our current knowledge of anterior pituitary cell lineage relationships may contribute to a better understanding of the origin of pituitary adenomas and tumors.
Abstract | Full Text | PDF (248 kb) - Transcription Factors and Hypopituitarism
Transcription Factors and Hypopituitarism
Trends in Endocrinology & Metabolism, Volume 10, Issue 8, 1 October 1999, Pages 326-332
Laurie E. Cohen, Sally Radovick and Fredric E. Wondisford
AbstractSeveral homeodomain factors are found in the developing anterior pituitary lobe. The production of these developmental transcription factors has distinct temporal and spatial patterns. By interacting with each other, as well as with other extrinsic and intrinsic signals, they control cell determination and specification. Here, we discuss transcription factors that have been shown to have an in vivo role in pituitary cell-type specification.
Abstract | Full Text | PDF (271 kb) - Anterior Pituitary Hypoplasia and Dwarfism in Mice Lacking the Dopamine Transporter
Anterior Pituitary Hypoplasia and Dwarfism in Mice Lacking the Dopamine Transporter
Neuron, Volume 19, Issue 1, 1 July 1997, Pages 127-138
Roger Bossé, Fabio Fumagalli, Mohamed Jaber, Bruno Giros, Raul R Gainetdinov, William C Wetsel, Cristina Missale and Marc G Caron
SummaryDeletion of the dopamine transporter (DAT) results in increased dopaminergic tone, anterior pituitary hypoplasia, dwarfism, and an inability to lactate. DAT elimination alters the spatial distribution and dramatically reduces the numbers of lactotrophs and somatotrophs in the pituitary. Despite having normal circulating levels of growth hormone and prolactin in blood, hypoplastic glands from DAT−/− mice fail to respond to secretagog stimulation. The effects of DAT deletion on pituitary function result from elevated DA levels that down-regulate the lactotroph D2 DA receptors and depress hypothalamic growth hormone-releasing hormone content. These results reveal an unexpected and important role or DA in the control of developmental events in the pituitary gland and assign a critical role for hypothalamic DA reuptake in regulating these events.
Summary | Full Text | PDF (447 kb) - …more
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Copyright © 1988 All rights reserved.
Cell, Volume 55, Issue 3, 505-518, 4 November 1988
Add/View Comments (0)The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein
Mordechai Bodner★, José-Luis Castriilo★, Lars E. Theill★, Thomas Deerinck†, Mark Ellisman† and Michael Karin★
a Department of Pharmacology School of Medicine, M-036 University of California, San Diego La Jolla, California 92093 USA
b Department of Neurosciences School of Medicine, M-008 University of California, San Diego La Jolla, California 92093 USA
- Growth hormone factor 1 (GHF-1) is a pituitary-specific transcription factor that plays a critical role in cell type-specific expression of the growth hormone (GH) gene. Here, we describe the isolation of bovine and rat GHF-1 cDNA clones. These cDNAs encode proteins whose molecular mass, 33K, is identical to purified GHF-1 and whose sequence agrees with a partial GHF-1 peptide sequence. The predicted GHF-1 sequence contains a region, near its C-terminus, that exhibits considerable similarity to a homeobox consensus sequence. DNAase I footprinting with bacterially expressed fusion protein containing a fragment of GHF-1 encompassing the homeobox indicates that this region of the protein functions as its DNA binding domain. Expression of GHF-1 is restricted to cells of the somatotropic lineage in the pituitary. This remarkable specificity of GHF-1 expression correlates with the selective transcription of its target, the GH gene. Other mammalian homeobox-containing proteins may function similarly as transcription factors controlling cell type-specific expression in other locations.


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Those dern Progressives, how in the world have we gotten along without them all these years?
In the News…
By Dub and Deb (Bio and Archives) Monday, November 26, 2012 Comments at bottom of page | Print friendly | Subscribe | Email Us |
Good morning guys! What's up? Been hangin out with a "younger crowd" over the holidays, thus, the "what's up?" I'd be willing to bet the last gatherin I was at there wasn't a single person there over 50??
Seems I'm becoming "the old man" at more and more of these gatherins! May have "winter" settin in on my head, but I'll be derned if I ain't STILL got some "spring" in my rear-end!" It's all in your attitude, course that Ensure stuff don't hurt either! LOL!
I hope everyone had a great Thanksgiving, and in doin so, I hope you remembered the REAL reason for this…our Lord and Savior, Jesus Christ.
I was sittin here this morning, checkin out the headlines. Pretty depressing anymore, wouldn't you say?
Let's take a gander at just a few…
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Nelson Rigg CL-MAP Magnetic Map Pouch
- Easily mounts to all shapes of metal tanks
- Clear map pouch unzips for quick map changes
- Nelson Rigg's lifetime no hassle warranty
- Available in Black only
Sizing Information
Available in Two sizes – Prices vary by size:
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The Nelson Rigg CL-Map Magnetic Map Pouch is a great solution for sportbike riders who want to keep that space behind the windscreen open but need to view a map while riding. Keep items in a tail bag and use a CL-Map pouch which will still allow you to get down behind that windscreen. Nelson Rigg Luggage comes with a warranty registration card, fill it out and register your luggage.


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Items by Amanda Peacher — 4 items
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For steelhead, dirty water might be better than clean
A wastewater treatment plant provides nutrients that help endangered steelhead thrive in an Idaho stream.
by Amanda Peacher, Jul 10, 2011 -
A Nez Perce elder spreads love for lamprey
Nez Perce elder Elmer Crow teaches children and their parents to respect an uncharismatic parasitic fish, the lamprey.
by Amanda Peacher, Feb 09, 2011 -
Foraging for fungi in the Pacific Northwest
A banner year for mushrooms raises questions about the science behind fungi and the impacts of wild harvesting.
by Amanda Peacher, Jan 11, 2011


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Property ID:
PRIME Boerum Hill 1BR; cats OK!
Price: $2,200.00
Location: Boerum Hill
Rooms: 3
Bedrooms: 1
Bathrooms: 1
Additional features: Pets Accepted (cats only)
This apartment on Smith Street in Boerum Hill is right in the heart of things. Lots of restaurants and shopping on the street, plus you are one block away from the Bergern Street F & G train stop. The apartment is recently renovated with brand new kitchen appliances, a reasonable amount of kitchen cabinets, and plenty of counter space for preparing meals or eating. Lots of natural light in this apartment from the two living room windows on the street side, and more windows from the back of the building, where the bedroom is located. From the bedroom you overlook the garden area. New fixtures throughout the apartment. Bring your cat(s)! This is a great starter size apartment with a terrific location for this price.h h/w included


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A smiley Bindi Irwin, 8, has taken over the the family business.
The precocious daughter of the late Crocodile Hunter Steve Irwin and wife Terri announced the upcoming "Bindi: Jungle Girl" series that will continue her father's work, saying, "The best part, I get to be with all my animal friends!"
Appearing in a tree house at the Australia Zoo, Terri said, "I think he would have said `Crikey mate, I couldn't wait for Bindi to take over.'" Answering criticism that it's too soon after Steve's death for Bindi to be back in the spotlight, mom said, "Bindi has been filming with us since she first hatched, it was a natural progression for her to be doing her own shows."
Steve Irwin died while diving nine months ago, when a stingray barb pierced his heart off the coast of Australia. The show launches stateside June 8.
to attack a CHILD is as nauseating, has this world become so polluted with filthy little girls that try to be grown up skanks that some of us DON'T KNOW WHAT A LITTLE GIRL SHOULD ACT & TALK LIKE anymore??
That, is how a happy little 8,9,10,11 year old SHOULD BE.
Or should she have a deep sex kitten voice and smoke cigarettes while ramming a deer with her range rover crying about how daddy's gone??
Maybe I'm cynical to think that a media career isn't necessarily the best way to protect a bereaved child's psychological welfare.
Some of these Hollywood drunk sluts should take a cue from this bright little girl. She has more class than all of them put together!
What's nauseating is to see a mother's interest put before her daughter's. No sooner has Steve died, then the mother is trying to recapture the limelight by throwing her daugher to the public or as I like to analogize the crocs. I wouldn't be surprised Bindi as an addict and or suicide victim by the time she's 18. Look at present day child actors and celebrity's, the streets and morgues are littered with them
I wish her the best of luck,,BUT,,IMO, shes just too young to have that responsibility, to stand in her fathers shoes..I agree with the poster above who said, give her a few years, and then let her make an adult decision.
They use Bindi, like Steve Irwin used Crocs- to make a buck. Its all about money for mama...
I would never pimp out my daughter like that. She is the same age as Bindi. Who knows what's going through the mother's head. If you put your kid in the spotlight, people are always going to make disparaging comments on websites like this. Don't blame people for saying the obvious, blame the parent for the decision.
it is a little creepy that she is so robotic, but i think this is something she wants to do (not that a child should dictate what they do), and it probably makes her feel closer to her dad, who she obviously loved very, very much.
i think terri is loving enough to pull the plug if it gets out of control. also, bindi will mature, and take on a more natural personality with time.
who are we to say what is right or wrong. they have suffered an amazingly huge loss. steve was larger than life. they are doing their best to fill the voids.
i wish them the best!
What an awesome kid!! Unlike much of Americas youth who are prowling the streets looking for their next victim or trying to get into clubs--and suceeding--this charming kiddo is carrying on something her tragically taken father began. And for you idiots who obviously know nothing about colloquial sayings in Austraila, yes she was hatched. Pick up a book or watch something besides Roseanne for a change.
Quit using this column for nothing but hating. Dont we have enough "young" people in our country who have screwed up their lives? When you see a kid who is doing well give them their props. And get over your selves.
This isn't something new. This was planned while her dad was still alive and he even filmed some of the first episodes with Bindi.
I do think it evident that Bindi loves doing this work, but think that moderation is called for considering her age. She needs to experience 'kiddom' as well as the media pressure.
I privately wonder if this would have been her career choice if it weren't one of the big ways she has to stay connected with her father, R.I.P.
My other concern is that if a sea creature ended her experienced 44 year old father's life, what ill-conceived fate could await this little girl unless strict safegaurds are always in place, and even then there's no gaurantee? There is the possibility that Mom could lose both, but I absolutely understand that you cannot & must not live in a bubble.
This is not a criticism, but simply a few concerns. Bindi seems happy and downright ecstatic, most of the time.
..................................Blessings, Little One....Many Blessings...............................


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Ex-Brazil President Says Chavez Should Look for Successor
Topic: Chavez's Cancer Battle
Venezuelan President Hugo Chavez
© AFP 2014/ PRESIDENCIAFormer Brazilian President Luiz Inacio Lula da Silva
© AFP 2014/ Yasuyoshi ChibaMEXICO, October 19 (RIA Novosti)
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Venezuelan President Hugo Chavez, reelected earlier in the month for the third presidential term, should start looking for a successor, former Brazilian President Luiz Inacio Lula da Silva said.
Chavez, 58, won re-election in October 7 polls with 54.6 percent of the vote to beat opposition challenger Henrique Capriles. The outspoken Socialist president will lead the Latin American country for another six years.
"I believe that Chavez became the best variant for Venezuela, but I also think that Chavez should start looking for a successor," said Lula da Silva, who ruled Brazil between 2002 and 2010.
The former president said Venezuela greatly benefitted under the rule of cancer-stricken Chavez and the course of his domestic and foreign policies should be maintained after his leaves his post, although the Constitution allows his to run for the fourth term.
Chavez, who has ruled Venezuela for 13 years, underwent three operations for cancer in the pelvic region and four courses of chemotherapy in Cuba and Venezuela within a year.
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Additional Physical Format: | Online version: Hart, William D., 1957- Black religion. New York ; Houndmills, Basingstoke, Hampshire : Palgrave Macmillan, 2008 (OCoLC)609328950 |
Named Person: | Malcolm X; Julius Lester; Janice Dean Willis; Malcolm X; Julius Lester; Janice Dean Willis; Julius Lester; Janice Dean Willis; Malcolm X |
Material Type: | Biography, Internet resource |
Document Type: | Book, Internet Resource |
All Authors / Contributors: |
William D Hart |
OCLC Number: | 176926075 |
Description: | xi, 228 p. ; 22 cm. |
Contents: | Afro-eccentricity and autobiography -- Jahiliyyah and Jihad -- Hijrah & Hajj -- Julius Lester: Blackness & Teshuvah -- Janice Willis: Duhkha and enlightenment -- Bluing the note -- Coda: my point of view as author. |
Responsibility: | William David Hart. |
More information: |
Publisher Synopsis
"This book will be very useful for courses in the study of religious autobiography...Highly recommended."--"Choice" "Hart is an original thinker. In this new book, he challenges and subverts the prevailing narrative about Black Religion, namely, that it is essentially Protestant Christianity in blackface, by presenting a constructive reading of the autobiographies of three black figures whose spiritual journeys led them away from Protestant roots to embrace, respectively, Islam, Judaism, and Buddhism. He traces conjunctions and disjunctions between the lives of Malcolm X, Julius Lester, and Jan Willis--figures he artfully characterizes as 'Afro-Eccentric'--adding a Coda describing his perspective as author that articulates one of the most brilliant accounts of religion anywhere. By so doing, Hart revises and expands the scope of the very term Black Religion in a profoundly sophisticated way. The richness, breadth, and depth of Hart's intellect radiate from every page."--Melvin K. H. Peters, Professor of Religion, Duke University "Hart's 'Afro-Eccentric' readings of Malcolm X, Julius Lester, and Jan Willis offer not only a fascinating trope for interpreting Black Religion, his readings mark a distinctive and singular point of departure into the varieties of African American religious experience. Surpassing the most current scholarship on the deployment of religious autobiography and black religious experience, Hart's 'Afro-Eccentric' readings set a new rigorous standard for the interpretation of 'difference' in black religious hermeneutics. A novel force to be reckoned with for a very long time to come."--Victor Anderson, Professor of Christian Ethics, Vanderbilt Divinity School "Every now and then an iconoclastic, and deeply personal voice, breaks through to challenge dominant stories within a field. I believe William Hart's latest book, "Black Religion", does exactly that."--"American Journal of Theology and Philosophy" Read more...
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- Conversion.
- African Americans -- Religion.
- Spiritual biography.
- Christianity and other religions.
- X, Malcolm, -- 1925-1965.
- Lester, Julius.
- Willis, Janice Dean.
- X, Malcolm.
- Schwarze Theologie.
- Spiritualität.
- Konversion <Religion>
- Schwarze.
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by owens1 updated 2009-02-17


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Over the course of the last two days, days that included two more brutal one-run losses for the Nationals, the question of luck has been posed several times to Nationals players and coaches. Seven of their last 11 games have been decided by one run. They've lost six of them.
"All that stuff about 'You guys are playing great and we're playing great and staying in the game,' at the end it doesn't add up," said Alex Cora. "You just want to win."
Matt Stairs smokes a ball Sunday afternoon with the tying run on base and it gets hit directly to the right fielder. Sean Burnett induces a ground ball from Phillies' slugger Ryan Howard and it's just squirts through the right side for an RBI-single instead of a double play. Ian Desmond gets to a ball even his closer didn't think he would in an attempt to stop the winning run from coming home and it gets away from him.
Things like this are happening over and over to the Nationals, especially recently, so it raises the question: Are the Nationals simply snakebit? Is it just bad luck?
There were differing views. Desmond denied the notion: "It's not about breaks," he said. "It's about playing baseball, playing the game the right way. I don't know. I honestly don't know. It's not luck. We're not unlucky. We have runners in scoring position and we can't score them."
Manager Jim Riggleman agreed when asked specifically about the play Desmond attempted to make in the ninth inning Sunday: "He made a great effort… It just trickled away. Is that unlucky? We had a chance to have good luck and we just didn't take advantage of it."
But there has to be some elements of luck involved.
The Nationals are, as they've said repeatedly, doing all of the "little things" right. They run the bases well, they've stolen 44 bases already this season — the fourth most in the National League — they bunt well, have played clean defense and gotten their power to come along some with homers in six of the last seven games.
But with their pitching staff finally starting to show signs of weakness after a superb start (their staff ERA of 3.90 is just below the Major League average), it's still not adding up to wins.
"A loss is a loss to me," second baseman Danny Espinosa said Monday when asked if there was any consolation in scoring four runs off Roy Halladay and being in contention to win. "I don't accept either one of them, personally. I don't think that if you play a bad game, it's just 'Oh, we just played a bad game and they took advantage of our mistakes.' It hurts just as much if you play a good game and you lose the game. It hurts and it can take you down just as much.
"It's tough luck. Sometimes things just go the other teams way."
It's been happening more often than not that way for the Nationals, who happen to face Cliff Lee at 7:10 p.m. tonight.


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Communications Office: Stephen Mease
Email: firstname.lastname@example.com
Phone: 802-865-6432
Robert Bloch, director of the unique-to-Champlain BYOBiz (Bring Your Own Business) program, followed up with nine of the most recent successful young entrepreneurs from Champlain College in the fall of 2011. He conducted interviews and compiled the dialogue into a new book, My Own CEO, published by the Champlain College Publishing Initiative. My Own CEO is a second edition of the former, Outside the Box, which was printed in 2011. Additions to the second edition include the story of the student-run coffee shop and convenience store in the IDX Student Life Center — The Lodge, as well as Tips for Young Entrepreneurs.
This book features nine students including:
These determined students share how they initially got their ideas, got others on board, and created unique opportunities to learn and grow by turning their passion into a hands-on education and income.
This book was created by Bloch with the entrepreneurially minded teenager in mind, to inspire anyone wondering whether to, and how to, take his or her dreams and ambitions into action. They'll give prospective students and entrepreneurs the strength to be their own CEO.
My Own CEO, Outside the Box, as well as books by both Ginger Vieira and Peter Garang Deng, were published by the Champlain Publishing Initiative, created by Tim Brookes to engage students in the field of publishing as writers, editors, designers, artists, marketers, publicists, accountants, or web designers. It gives students a supervised educational experience that is creative, demanding, and applicable to the world they meet when they graduate. Champlain Publishing Initiative's mission is to be an active part of the great experiment that is contemporary publishing, and to offer the greater-Champlain community the chance to get involved and get published. For more information, please visit www.champlaincollegepublishing.com.
Champlain College, known for its professionally oriented academic programs, has had various entrepreneurship clubs present on campus since 1985. With the increasing demand of a more professionally organized club, the group evolved into an innovative entrepreneurship education program called BYOBiz (Bring Your Own Business) in 2006.
In the BYOBiz program, one can network and learn from successful entrepreneurs and other local experts in the strategic, financial, legal, technical, operational and managerial sectors of business ownership. Director Bob Bloch acts as a mentor and guides students' ideas in the most opportune direction and connects them to outside sources.
"They are undaunted; they see possibilities and you can just feel the energy they exude and their motivation to succeed," said Bloch, "The students bring businesses from home or create new ones to add to Burlington's growing small business community. They are passionate and are willing to take risks to achieve their goals.
To learn more about the BYOBiz program, please visit their website or contact Champlain College Admissions to be sent a copy of My Own CEO by BYOBiz Director Bob Bloch.
Since 1878, Champlain College has provided career-focused education to students from its hilltop campus in Burlington, Vt. Champlain's distinctive educational approach embodies the notion that true learning only occurs when information and experience come together to create knowledge. Champlain offers traditional undergraduate and online undergraduate courses, along with online certificate and degree programs and eight master's degree programs. Champlain offers study abroad programs at its campuses in Montreal, Quebec and Dublin, Ireland. Champlain College is included in the Princeton Review's The Best 378 Colleges: 2014 Edition. Champlain was named a "Top-Up-and-Coming School" by U.S. News & World Report's America's Best Colleges and is ranked in the top tier of 2013 Regional Colleges in the North. For more information, visit www.champlain.edu


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Fischer Tradition Amber - Brasserie Fischer / Fischer Biere d' Alsace
Displayed for educational use only; do not reuse. |
Ratings: 337 | Reviews: 263 | Show All Ratings:
3.85/5 rDev +31.8%
look: 4 | smell: 4 | taste: 4 | feel: 3.5 | overall: 3.5
The way I remembered Grolsch as a teenager. The swing cap makes for a good reseal, but hey, who's resealing? Poured a nice light amber color, had a refined hops taste, but the sweetness was still there. Not my kind of style, but still very drinkable. I'd hate to drink too much of this, it must taste terrible coming up.
Serving type: bottle
12-16-2002 06:24:01 | More by bewareOFpenguin
2.05/5 rDev -29.8%
look: 3 | smell: 2 | taste: 2 | feel: 2 | overall: 2
Dull golden bodied. Eruptive pure white sticks around. If nothing else, Fischer has mastered head retention.
Hay, must and rubber on the nose.
Basically a lightly toasted version of the bitter. I had them back to back, and there is not a whole lot of difference. The amber displays the same lemon/lime sourness, but to a lesser degree. Filling the void is some slight toastedness. No real caramel or vienna maltiness. Rubber seems to be Fischer's trademark flavor, and it shows up here again. Alcohol brings some sticky sweetness. It is way too perceived for a brew of this size. Slightly grainy, rustic hops finish this one off....finally.
Medium bodied, but lightly sticky and not all that pleasant in the mouth.
A great big "boo" to Fischer. Unless I need a flip top 22oz bottle, I doubt I'll ever buy anything from them again.
Serving type: bottle
11-30-2002 23:46:09 | More by cokes
2.38/5 rDev -18.5%
look: 3.5 | smell: 2.5 | taste: 2 | feel: 3 | overall: 2.5
Pours a clear light amber/orange with a large white head that leaves a nice lace down the glass. The aroma is quite unusual for a pale ale as I am picking up a sweet grape smell. Although not unpleasant, it is quite unexpected! Woah! Okay the grapes are still included in the taste too. Very strange! It is like a beer-wine hybrid. I'll try to explain the taste but I fear I cannot do it justice. Mostly white grape flavored with dominant alcohol on the tail with very light hops. This is one weird brew! I dunno about this one! A votre sante!
Serving type: bottle
11-27-2002 20:26:39 | More by BeerAngel
1.93/5 rDev -33.9%
look: 4 | smell: 2 | taste: 1.5 | feel: 2.5 | overall: 2
nice amber color with an impressive foamy head and lots of lace. smells odd...i interpret it as a grape/white wine aroma that doesn't belong in beer. tastes sour...more of that winey taste overpowers the underlying caramel malt base. not enjoyable. hops? i can't tell...there is some sort of bitterness that i suppose is a hop bite in the end. the only reason i drank the whole 24 oz bottle is because i really was trying to figure out what the hell i was tasting. cool flip top bottle...bad beer. YUK!
Serving type: bottle
10-29-2002 09:44:08 | More by budgood1
3.35/5 rDev +14.7%
look: 3 | smell: 3.5 | taste: 3 | feel: 3.5 | overall: 4
It has golden, dark straw color to it. The smell is aromatic with a nutty flavor and minimal hops. It has a decent taste much better than most malt liqours I usually drink. It has a caramel flavor that stands out on my tongue. The mouthfeel is just okay but the drinkability is better and makes it a very smooth drink. This is just an average brew with really cool packaging. I like it just okay but probably won't get it again, unless there are some unforeseen circumstances.
Serving type: bottle
09-27-2002 11:46:12 | More by tang214
1.95/5 rDev -33.2%
look: 3.5 | smell: 2.5 | taste: 1.5 | feel: 2 | overall: 2
Medium brown/golden color with a good 1/2 inch head with character. Husky smell, a little nut and a little sulfur. Seedy flavor, seriously strays toward papery (some reminders of that paste some kids ate in First Grade). Some metallics as well. Light mouthfeel and a bit of a dry finish with some lime. This brew is pretty dang foul, I had to struggle to finish the second glass. At least it comes in singles, but a swing top only has limited amusement value when faced with this mixture of wheat paste and mostly dried rubber cement.
Serving type: bottle
08-23-2002 07:49:50 | More by ADR
1.88/5 rDev -35.6%
look: 4 | smell: 2.5 | taste: 1.5 | feel: 3 | overall: 1
This beer pours a very nice amber with a chunky off-white head. The smell is sweet-apple something. The taste kills this beer for me. I hate ciders and this tastes way too much like a cider. Way to freaking sweet! It is smooth but once the taste hits yuck! I did not care for this at all and I will struggle to finish this beer.
If this beer is flawed (and maybe it is) I doubt if I will ever find out because this beer was crap. Way to go France!
This rating is inflated based on its look!
Serving type: bottle
08-09-2002 14:18:14 | More by bditty187
1.83/5 rDev -37.3%
look: 3 | smell: 2.5 | taste: 1.5 | feel: 2 | overall: 1.5
Fischer Amber From France: In a cool flip top bottle. It is too bad the beer doesn't come close to living up to the packaging. The aroma is very sweet. The beer tastes more like cider than an amber brew, and is cloyingly sweet. Truly awful, and as it warmed up, it got worse. Bad.
Serving type: bottle
07-25-2002 08:18:38 | More by jackndan
2.2/5 rDev -24.7%
look: 4 | smell: 2 | taste: 2 | feel: 3 | overall: 2
Clear and bright amber beer with a massive froth of a creamy ass head that sticks and stays. Metallic in the nose with wet paper aromas -- why me?
Wet paper carries over to the flavour, which leads me to believe that my sample is tainted with some minor oxidation. Sucks, but we move on ... malt flavours are grainy, barely sweet, but there's some fruity flavours that attempt to meld with the citric hop flavours that seems a bit contrived. Again, I'm disappointed. Mouthfeel is smooth-ish, body is light. Finish is clean with some residual grain flavours and a coarse leftovers on the palate.
There's too many beers in the world to waste your time with this one. Cool flip-top ceramic bottle though, but unfortunately that does not make a beer.
Serving type: bottle
06-25-2002 20:20:43 | More by Todd
New Jersey
2.8/5 rDev -4.1%
look: 3.5 | smell: 2.5 | taste: 2.5 | feel: 4 | overall: 3
Bright amber in color with a very clear look and a lasting white head and lace. The nose was very musty traditional beer smell. Malty smooth mouth and taste but with a slightlt metalic/cardboard/tin finish. This brew has great mouthfeel but there is nothing at all special in the flavor. I was quite dissapointed in relation to the other posted reviews.. maybe I got a bad one...? The bottle (flip top and church imprinted) was better than the brew.
Serving type: bottle
06-04-2002 19:02:14 | More by frank4sail
4.13/5 rDev +41.4%
look: 4.5 | smell: 4 | taste: 4 | feel: 4 | overall: 4.5
This is my first french beer and I was expecting something alittle lighter tasting. Dark amber with a thick white head that left thick lace down the sides of the glass. Sweet malt and a even hopiness with a clean/dry ending. The champagne like pop of the stopper added to the novelty of trying this beer.
Serving type: bottle
05-06-2002 10:24:03 | More by xXTequila
3.23/5 rDev +10.6%
look: 3 | smell: 3 | taste: 3.5 | feel: 3 | overall: 3
This beer holds a special place for me. It was one of the first non-American-macros I ever tried. I used to drink it at an upscale seafood restaurant my wife and I use to go to when we were engaged (man, that was over a decade ago). Upon revisiting this amber beverage, I found it to have a nice malt presence, with a lower-than-remembered hop finish.
Serving type: bottle
04-25-2002 10:41:39 | More by proc
3.68/5 rDev +26%
look: 4 | smell: 3.5 | taste: 3.5 | feel: 4 | overall: 4
Presentation: 22 oz brown flip top with raised glass designs. No freshness date.
Appearance: Crystal clear tawny amber with a thick rocky head that holds up like a champ all the way down to the bottom of the glass.
Smell: Subtle hoppy twang and lots of sweet grain in the nose with hints of apple peel and caramel.
Taste: Moderately bodied with a crisp biting carbonation that helps emphasize the hop bitterness. Clean palate and on the dry side. Mild cidery apple twang and a mouthful of clean grain are the forefront of this brew. Hops linger with the amongst the apple like fruitiness far into the finish.
Notes: A good brew to wash down nearly any kind of cuisine or even to drink as a session brew. A flavourful lager to experience, glad I had a chance to. Flavours are level and well formed, give this one a try.
Serving type: bottle
08-22-2001 01:13:01 | More by Jason
Fischer Tradition Amber from Brasserie Fischer / Fischer Biere d' Alsace
out of 100
based on 337 ratings.


text:
What does PTEI stand for?
What does PTEI mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: PTEI.
We've found 1 definition for PTEI:Sort:PopularA - ZCategory
PTEI | Pittsburgh Tissue Engineering Initiative |
Still can't find the acronym definition you were looking for? Use our Power Search technology to look for more unique definitions from across the web!
"PTEI." Abbreviations.com. STANDS4 LLC, 2014. Web. 14 Mar. 2014. <http://www.abbreviations.com/PTEI>.


text:
If hot hatches are your thing, this year's Geneva Motor Show is the place to be. Seat used the occasion to reveal its Ring-running Leon Cupra. Not to be outdone, Honda showed up with its Civic Type R concept. VW has got the new Scirocco R and Golf GTE to show off, Audi finally bestowed the new S1 upon us and Abarth transformed the Fiat 500 into the bonkers 695 Biposto. Even Alfa Romeo got in on the action with the latest QV edition MiTo and Giulietta. But the lineup wouldn't be complete without the Opel Astra OPC Extreme.
Arguably the ultimate expression from the Opel Performance Center, the Astra Extreme packs a 2.0-liter turbo four with 300 horsepower, a six-speed stick and limited-slip differential underneath the most outlandishly extreme aero kit this side of a DTM racer. Everything's made of carbon fiber and the cabin's stripped out for business to make it 220 pounds lighter than the standard Astra OPC/VXR and closer in spirit and appearance to the Astra OPC Cup that challenges the VLN series at the Nürburgring.
It's a beast of a hot hatch if there ever was one, but at the moment, the press release below describes it as a "study for low-volume production." We just hope Opel and its British sister Vauxhall will actually make it, but even then, it's not likely to ever find its way across the Atlantic, even with those giant wings. Indulge in the Opel madness with the video below.


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KKCO Mobile Site
Back to Sports
Football playoffs: next round of match-ups
Posted: 9:50 PM Nov 10, 2012
Reporter: Krystle Sonmore
GRAND JUNCTION, Colo. (KKCO) - Four Western Slope teams are still in the playoffs. Here are the match-ups.
Class 1A Semifinals:
(3)Cedaredge Bruins @ (10)Hotchkiss Bulldogs
Class 3a Round 2:
(1)Rifle Bears vs. (8)Roosevelt Roughriders
(13)Delta Panthers vs. (5)Pueblo East Eagles
*All dates and times TBD. For full brackets, visit CHSAA.org.
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Based on the novel Cool Hand Luke by Donald Pearce (New York, 1965).
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I'm discontented with homes that are rented so I have invented my own
Darling this place is a lover's oasis where lights where we chase is unknown
Far from the cry of the city where flowers pretty caress the stream
Cozy to hide in, to live side by side in, don't let it abide in my dream
Picture you upon my knee, just tea for two and two for tea
Just me for you and you for me alone
Nobody near us to see us or hear us
No friends or relations or weekend vacations
We won't have it known, dear, that we own a telephone, dear
They will brake and you'll awake and start to bake a sugar cake
For me to take for all the boys to see
We will raise a family, a boy for you and a girl for me
Can't you see how happy we will be
Writer(s): Vincent Youmans, Irving Caesar
Copyright: Irving Caesar Music Corp., WB Music Corp.
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Dec 2 2009 by Jane Clare, Birkenhead News
WIRRAL is to hold its first tweet-up next week ... and it's all in the name of charity.
A tweet-up is a gathering of people who use Twitter, the social online networking site which is growing in popularity.
Cromwells Restaurant in Irby, is to host the first tweet-up next Monday, December 7, from 5.30pm, when up to 35 "twitterers" will meet; some for the first time, despite conversing across the ether for several months!
The event is fully-booked, but Cromwells – who are providing a free buffet – and fellow organisers Koogar, are now looking for donations for a raffle.
All proceeds are going to Clatterbridge Cancer Research, which has been
To donate, contact Kay at Cromwells on 0151 648 9898.
To view the raffle prizes donated so far, go to http://www.cromwells-irby.co.uk/tweetup.
If you live in Wirral and twitter, and would like to knowabout future tweet-ups, then follow @wirraltweetup.


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Fast-food workers in more than 50 cities Thursday are striking for fair pay and the right to form a union — the biggest walkout to hit the industry. This latest round of labor unrest comes 50 years after hundreds of thousands of Americans, led by Martin Luther King Jr., joined the March on Washington for Jobs and Freedom, demanding not only civil rights, but also good jobs and economic equality.
One demand of the 1963 marchers was raising the federal minimum wage to $2 an hour. In today's dollars, that's roughly $15 an hour — what the striking fast-food workers are now calling for.
For all the progress made since 1963, the reality is that economic inequality persists and continues to grow. Income inequality is greater today in the U.S. than in any other OECD nation, except Chile, Mexico and Turkey, and exceeds that of many developing countries.
Almost one-quarter of all jobs in the United States pay wages below the poverty line for a family of four. CEO compensation, meanwhile, continues to climb. It would take a full-time, minimum-wage worker more than 930 years to earn as much as the chief executive officer of Yum! Brands, which operates Taco Bell, Pizza Hut and KFC, made in 2012.
Fast-food workers are in the lowest paid occupational category. The median hourly wage for frontline fast-food workers is $8.94 nationally. Many don't even earn that. A shortage of hours further limits income. Fast-food workers work only 24 hours a week on average — at $8.94 an hour, this adds up to barely $11,000 a year.


text:
Eric Buckley
Bangkok, Thailand
Bio not provided
@arpowers I understand how these things go ... just thought I would ask. I'm looking forward to the launch.
7 months, 4 weeks ago on The PageLines 300
Hi Andrew,
So when do we all get hear if we are members of the team?


text:
Information Studies
DIS staff blog
DIS student blog
- An infographic produced by UCLDH and 4Humanities has won an award
- David Ryan (UCL CDIP Archive Studies, 1987) has received an LVO for outstanding service in the New Year's Honours List. He works for the Royal Household as Director of Records.
- A blog by Molly Slight, one of our MA Publishing students, has been published on the Bookseller website.
INSTG063: Introduction to Digitisation
In the 2013/2014 academic year, this course is offered as an option to the MA/MSc in Digital Humanities only, given it is the first time that this course will be in operation.
This module will serve as a practice-led introduction to the digitisation of cultural and heritage materials in the library, archive, museums and galleries sector. It is an advanced level module taught in two ways: theory and principle led lectures and tutorials, and hands on sessions in the computer lab and in the UCLDH Multi-modal digitisation suite (a custom built space for teaching and researching digitization at UCL). This module will also involve close liaison with UCL Museums and Collections, UCL Library Special Collections, and UCL Media Services to provide practical hands on teaching to understand the technical underpinnings but practical application of digitisation in the cultural and heritage sector.
Subjects to be covered include:
• Principles of digitisation
• Handling of objects and documents
• Digitisation studio set up
• Metadata and object information
• Use and Usability of digitised content
• 2D versus 3D digitisation
• Funding and costs
• The digitisation lifecycle – from institutional store to digital repository
• Best practice in digitisation
On successful completion of this module students will be able to:
1. Assess objects for digitisation, and understand handling conditions
2. Undertake 2D digitisation of archival material (using SLR and scanner) using best practice principles
3. Be aware of the various 2D and 3D technologies available for digitisation in the cultural and heritage sector
4. Understand the technical underpinnings of digitisation, including capture methods, file formats, compression methods, etc.
5. Understand metadata and preservation issues related to digitisation
6. Understand how and why digitisation technologies have been employed throughout the GLAM sector
7. Understand the technological and financial frameworks which have encouraged the uptake of digitisation
8. Have an awareness of the complete digitisation life cycle, from transportation of object from store, to deposit of digital surrogates in institutional repository (and beyond)
9. Be familiar with key technologies: both hardware and software.
Each teaching session consists of a lecture plus at least one other session, which may be a practical, guest lecture, or visit to a resource.
Assessment: Assessment by coursework only. A group digitisation project plus written commentary, and individual reflection essay.
Compulsory for: No students
Optional for: In the 2013/2014 academic year, this course is offered as an option to the MA/MSc in Digital Humanities only.
Prerequisites: There are no formal prerequisites for this module.
Taught by: Professor Melissa Terras
This module runs on Tuesday mornings in Term 1.
Further information for students currently taking this module
Information for prospective students (coming soon!)
Page last modified on 19 sep 13 14:27


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- FrontPage Magazine - http://www.frontpagemag.com -
Hot Post: Since When Does Being Made a Fool of Constitute Rape?
Posted By Christine Williams On October 3, 2010 @ 9:00 am In NewsReal Blog | No Comments
This popular post was first published here.
Woman in Canada meets man on Internet dating site– a self-described bachelor looking for a long term relationship. They fall in 'love', hit the sack and now she's crying rape:
In the moment, the sex felt consensual — welcomed even. In retrospect though, Minki Basu believes she was violated, her consent allegedly negated by a deception so "morally reprehensible" that each instance of intercourse with Kaz Akbar "constitutes a separate sexual assault.
After five months into a relationship, Minki Basu found out that "Kam Ali" was really Kaz Akbar–a married man with children who had deceived her. She then went on a vengeance spree; according to court documents Basu went to sites where she openly exposed Akbar, in turn putting her at the receiving end of a civil suit by Akbar. Now she is countersuing on the grounds that he threatened to release a secret sex video. She's also alleging rape. The case is dizzying to say the least but in the midst of this complicated war in court, the paramount debate is: What constitutes sexual assault?
According to one Toronto based Clinical Psychologist and University Lecturer:
"To me, this is almost an insult to those who have been sexually assaulted," said Dr. Oren Amitay, adding that deception "happens all the time" in the mating game. "She was used, she was lied to — and so was about 90-something percent of the female population."
Ms. Basu's trauma is "quite different" and is more about a "feeling of 'I was lied to. I was made a fool of."
Article printed from FrontPage Magazine: http://www.frontpagemag.com
URL to article: http://www.frontpagemag.com/2010/christine-williams/hot-post-since-when-does-being-made-a-fool-of-constitute-rape/
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