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Sami people, also spelled Sámi, or Saami are the arctic indigenous people inhabiting Sápmi, which today encompasses parts of far northern Sweden, Norway, Finland and the Kola Peninsula of Russia, but also in the border area between south and middle Sweden and Norway. The Sámi are Europe's northernmost and the Nordic countries' only officially indigenous people.[6] Sami ancestral lands span an area of approximately 388,350 km2 (150,000 sq. mi) which is comparatively about the size of Sweden in the Nordic countries. Their traditional languages are the Sami languages. The Sami languages are endangered, and are classified as a branch of the Uralic language family.
Traditionally, the Sami have plied a variety of livelihoods, including coastal fishing, fur trapping, and sheep herding. Their best known means of livelihood is semi-nomadic reindeer herding – which about 10% of the Sami are connected with and 2,800 actively involved with full-time.[7] For traditional, environmental, cultural, and political reasons, reindeer herding is legally reserved only for Sami people in certain regions of the Nordic countries.[8]
Since the early years of genetic research, the Sami people have caught the interests of scientists. The Sami languages belong to the Uralic languages family of Eurasia. Some older anthropologist have suggested they might be of Asian and/or Siberian origin. The frequency of blood group and protein polymorphisms in Sami differ significantly from the general Swedish population.[1]
In more recent years the use of mitochondrial DNA (mtDNA) and Y-DNA chromosomal markers has offered the opportunity for clarification of the origin of the Sami. While their mtDNA haplogroup distribution overwhelmingly represents a subset of the European gene-pool, the most common Y-DNA haplogroup among the Sami is widely believed to be of Eurasian origin and very common among all peoples in Northeastern Europe. The second most common haplogroup is I, which is found almost exclusively among those of European ancestry. Thus the Sami appear to have a complex population history, suggesting a mixture of peoples arriving in Fenno-Scandia at different times, from different directions. Their most common physical appearance is northern European like Finns or Scandinavians.[2]
Population genetics of the Sami
mtDNA Haplogroups
Classification of the Sami mtDNA lineages revealed that the majority are clustered in a subset of the European mtDNA pool. The two haplogroups V and U5b dominate, between them accounting for about 89% of the total. This gives the Sami regions the highest level of Haplogroups V and U5b thus far found. Both haplogroups V and U5b are spread at moderate frequencies across Europe, from Iberia to the Ural Mountains. Haplogroups H, D5 and Z represent most of the remaining averaged total. Overall 98% of the Sami mtDNA pool is encompassed within haplogroups V, U5b, H, Z, and D5. Local frequencies among the Sami vary.[3] The divergence time for the Sami haplogroup V sequences was estimated by Max Ingman and Ulf Gyllensten at 7600 YBP (years before present), and for U5b1b1 as 5500 YBP amongst Sami and 6600 YBP amongst Sami and Finns. This suggests to them an arrival in the region soon after the retreat of the glacial ice.[4]
Although a small proportion of the Haplogroup U (mtDNA) among the Sami falls into U4, the great majority is U5b. The percentage of total Sami mtDNA samples tested by Tambets and her colleagues which were U5b ranged from 56.8% in Norwegian Sami to 26.5% in Swedish Sami.[3] Sami U5b falls into subclade U5b1b1. The Sami U5b1b1 [3] sub-clade is present in many different populations, e.g. 3 % or higher frequencies in Karelia, Finland, and Northern-Russia.[3] The Sami U5b1 motif is additionally found in very low frequencies for instance in the Caucasus region, however this is explained as recent migration from Europe.[5] However 38% of the Sami U5b1b1 mtDNAs have haplotype so far exclusive to the Sami, containing a transition at np 16148.[3]
Alessandro Achilli and colleagues noted that the Sami and the Berbers share U5b1b, which they estimated at 9,000 years old, and argued that this provides evidence for a radiation of the haplogroup from the Franco-Cantabrian refuge area of southwestern Europe.[6]
As mentioned above, the divergence time for the Sami haplogroup V sequences was estimated by Max Ingman and Ulf Gyllensten at 7600 years ago.[4] Haplogroup V is by far the most frequent haplogroup in the Swedish Sami and is present at significantly lower frequencies in Norwegian and Finnish subpopulations.[3] Torroni and colleagues have suggested that the spread of haplogroup V in Scandinavia and in eastern Europe is due to its late Pleistocene/early Holocene expansion from a Franco-Cantabrian glacial refugium.[7]
However subsequent studies found that haplogroup V is also significantly present in eastern Europeans. Furthermore, haplogroup V lineages with HVS-I transitions 16153 and 16298 that are frequent in the Sami population are much more widespread in eastern than in western Europe. So haplogroup V might have reached Fennoscandia via central/eastern Europe. Such a scenario is indirectly supported by the absence, among the Sami, of the pre-V mtDNAs that are characteristic of southwestern Europeans and northwestern Africans.[3]
Haplogroup Z is found at low frequency in the Sami and Northern Asian populations but is virtually absent in Europe. Several conserved substitutions group the Sami Z lineages with those from Finland and the Volga-Ural region of Russia. The estimated dating of the lineage at 2700 years suggests a small, relatively recent contribution of people from the Volga-Ural region to the Sami population. [4]
Three Y chromosome haplogroups dominate the distribution among the Sami: N1c (formerly N3a), I1 and R1a. The most common haplogroup among the Sami is N1c, with I1 as a close second. Haplogroup R1a in Sami is mostly seen in the Swedish Sami and Kola Sami populations, with a low level among the Finnish Sami. Tambets and colleagues suggested that N1c and R1a probably reached Fennoscandia from eastern Europe, where these haplogroups can be found in high frequencies.[3]
However the two haplogroups have a distinctly different linguistic distribution. R1a1a is common among Eastern Europeans speaking Indo-European languages, while N1c correlates closely with the distribution of the Finno Ugrian languages. For example N1c is common among the Finns, while haplogroup R1a is common among all the neighbours of the Sami.[8] Haplogroup I1 is the most common haplogroup in Sweden, and the Jokkmokk Sami in Sweden have similar structure as among Swedes and Finns for haplogroup I1 and N1c.[9]
See also
Y-DNA haplogroups by ethnic groups
^ L.E. Beckman, K. Sjoberg, S. Eriksson and L. Beckman (2001). "Haemochromatosis gene mutations in Finns, Swedes and Swedish Saamis". Human Heredity 52 (2): 110–112. PMID 11474212.
^ http://www.nordicway.com/search/Sami.htm
^ a b c d e f g h Kristiina Tambets, Siiri Rootsi, Toomas Kivisild, Hela Help, Piia Serk et al. (2004). "The Western and Eastern Roots of the Saami—the Story of Genetic "Outliers" Told by Mitochondrial DNA and Y Chromosomes". American Journal of Human Genetics 74: 661–682. doi:10.1086/383203. PMC 1181943. PMID 15024688.
^ a b c Max Ingman and Ulf Gyllensten (2007). "A recent genetic link between Sami and the Volga-Ural region of Russia". European Journal of Human Genetics 15 (1): 115–120. doi:10.1038/sj.ejhg.5201712. PMID 16985502.
^ Martin Richards et al. (2000). "Tracing European Founder Lineages in the Near Eastern mtDNA Pool". American Journal of Human Genetics 67: 1251–1276. doi:10.1016/S0002-9297(07)62954-1. PMC 1288566. PMID 11032788.
^ Achilli, Saami and Berbers (2005). "An Unexpected Mitochondrial DNA Link". American Journal of Human Genetics 76: 883–886. doi:10.1086/430073. PMC 1199377. PMID 15791543.
^ A. Torroni et al. (2001). "A signal, from human mtDNA, of postglacial recolonization in Europe". American Journal of Human Genetics 69: 884–885. doi:10.1086/323485. PMC 1226069. PMID 11517423.
^ Tuuli Lappalainen, Satu Koivumäki, Elina Salmela, Kirsi Huoponen, Pertti Sistonen, Marja-Liisa Savontaus, Päivi Lahermo (2006). "Regional differences among the Finns: A Y-chromosomal perspective". Gene 376 (2): 207–215. doi:10.1016/j.gene.2006.03.004. PMID 16644145.
^ Andreas O Karlsson, ThomasWallerström, Anders Götherström and Gunilla Holmlund (2006). "Y-chromosome diversity in Sweden – A long-time perspective". European Journal of Human Genetics 14 (8): 963–970. doi:10.1038/sj.ejhg.5201651. PMID 16724001.
The sequencing of entire human mitochondrial DNAs belonging to haplogroup U reveals that this clade arose shortly after the "out of Africa" exit and rapidly radiated into numerous regionally distinct subclades. Intriguingly, the Saami of Scandinavia and the Berbers of North Africa were found to share an extremely young branch, aged merely ?9,000 years. This unexpected finding not only confirms that the Franco-Cantabrian refuge area of southwestern Europe was the source of late-glacial expansions of hunter-gatherers that repopulated northern Europe after the Last Glacial Maximum but also reveals a direct maternal link between those European hunter-gatherer populations and the Berbers.
Saami and Berbers—An Unexpected Mitochondrial DNA Link
Alessandro Achilli,1 Chiara Rengo,1 Vincenza Battaglia,1 Maria Pala,1 Anna Olivieri,1 Simona Fornarino,1 Chiara Magri,1 Rosaria Scozzari,2 Nora Babudri,3 A. Silvana Santachiara-Benerecetti,1 Hans-Jürgen Bandelt,4 Ornella Semino,1 and Antonio Torroni1
1Dipartimento di Genetica e Microbiologia, Università di Pavia, Pavia, Italy; 2Dipartimento di Genetica e Biologia Molecolare, Università "La Sapienza," Rome; 3Dipartimento di Biologia Cellulare e Ambientale, Università di Perugia, Perugia, Italy; and 4Fachbereich Mathematik, Universität Hamburg, Hamburg
Address for correspondence and reprints: Dr. Antonio Torroni, Dipartimento di Genetica e Microbiologia, Università di Pavia, Via Ferrata 1, 27100 Pavia, Italy. E-mail: email@example.com
Received January 21, 2005; Accepted March 3, 2005.
Because of maternal transmission and lack of recombination, the sequence differentiation of human mtDNA has been generated by only the sequential accumulation of new mutations along radiating maternal lineages. Over the course of time, this process of molecular divergence has given rise to monophyletic units that are called "haplogroups." Because this process of molecular differentiation occurred mainly during and after the process of human colonization of and diffusion into the different continents and regions, haplogroups and subhaplogroups tend to be restricted to specific geographic areas and population groups (Wallace 1995; Achilli et al. 2004).
Only the founders of the sister superhaplogroups M and N (which includes haplogroup R) (Quintana-Murci et al. 1999) participated in the "out of Africa" exit (Cann et al. 1987; Stringer and Andrews 1988; Cavalli-Sforza et al. 1994; Underhill et al. 2000; Forster et al. 2001) and were successful in colonizing the rest of the Old World. Superhaplogroup N is globally distributed outside Africa, encompassing virtually all of the western Eurasian mtDNA variation, and embraces haplogroup U, nested in haplogroup R. Haplogroup U has an extremely broad geographic distribution that ranges from Europe and North Africa to India and Central Asia and has a very high overall frequency (15%–30%) (Richards et al. 2000; Kivisild et al. 2003; Quintana-Murci et al. 2004)
To assess the nature and extent of haplogroup U variation, we initially sequenced 28 entire U mtDNAs (see authors' Web site and GenBank) from a wide range of populations. These were selected through a preliminary sequence analysis of the mtDNA control region to include the widest possible range of haplogroup U internal variation. A tree of the mtDNA sequences (fig. 1) reveals that haplogroup U first splits into two major subsets, distinguished by the mutation at nt 1811, and that there is a very large number of independent basal branches. Among these, representatives of all known subhaplogroups (U1–U9) were included. However, subhaplogroup U5 provided a rather intriguing result. A Yakut from northeastern Siberia (27 in fig. 1) and a Fulbe from Senegal (29 in fig. 1) harbored mtDNAs that differed at only two coding-region nucleotide positions.
Figure 1
Figure 1
Tree of 39 mtDNA sequences belonging to haplogroup U. The tree, rooted using the reference sequence (rCRS) (Andrews et al. 1999) as an outgroup, illustrates subhaplogroup affiliations. The sequencing procedure and phylogeny construction were performed (more …)
To investigate this striking similarity, the portion of the tree encompassing these two mtDNAs was enriched by sequencing 11 additional mtDNA sequences (22–26, 28, 30, 32, 34, 36, and 37 in fig. 1) bearing the control-region motif 16270-150, a motif found generally at low frequencies (<2%) in Berber populations and in other African groups (such as the Fulbe) known to have intermingled with Berbers (Rosa et al. 2004). The motif also shows similarly low frequencies in virtually all European populations, except the Saami of northern Scandinavia, in which it reaches ?48% (Tambets et al 2004). Because virtually all Saami mtDNAs with 16270-150 harbor the transitions at nts 16189 and 16144 seen in the Yakut mtDNA, three Saami mtDNAs were included among the additional samples.
Seven of the new sequences (one Berber from Algeria, two Italian, one Spanish, and three Saami) clustered into U5b1b, the subclade encompassing the Yakut and Fulbe mtDNAs. The Saami and the Yakut mtDNAs formed a minor branch distinguished only by the transition at nt 16144, the Berber and the Fulbe mtDNAs clustered in a second minor branch also characterized only by control-region mutations, and the Italian and Spanish mtDNAs formed other minor branches.
The average sequence divergence (± SE, computed as per Saillard et al. [2000]) of the 39 coding-region sequences from the root of haplogroup U was 11.4 ± 1.3 substitutions (disregarding indels and pathological mutations), a value which corresponds—according to the mutation-rate estimate of Mishmar et al. (2003)—to a coalescence time estimate of 58.8 ± 6.8 thousand years (ky) for the entire haplogroup U. This value agrees well with the corresponding estimate of 61.6 ± 12.5 ky, based on the hypervariable segment I (HVS-I) mutation rate (Forster et al. 1996), for these 39 mtDNAs. An age of ?60 ky indicates that haplogroup U arose very soon after the "out of Africa" exit. As for U5, its sequence divergence was 8.1 ± 1.8 substitutions, corresponding to 41.4 ± 9.2 ky, a time estimate in full agreement with its proposed proto-European origin (Richards et al. 2000). It is striking that the sequence divergence of U5b1b, the subclade encompassing mtDNAs from the Saami, Yakut, Berbers, and Fulbe, was 1.7 ± 0.5 substitutions, thus corresponding to only 8.6 ± 2.4 ky.
Such a recent common ancestry of maternal lineages found in populations living as far as 9,000 miles apart and whose anthropological affinities are not at all obvious is, to say the least, unexpected. Can we provide a reasonable explanation? The recent molecular dissection of other mtDNA haplogroups reveals some clues. H1 and H3, two frequent subhaplogroups of H, display frequency peaks centered in Iberia and surrounding populations, including the Berbers of Morocco, and coalescence ages of ?11 ky (Achilli et al. 2004). Furthermore, their frequency patterns and ages resemble those reported for haplogroup V (Torroni et al. 2001a)—which, similar to U5b1b, is extremely common only in the Saami (together, U5b1b and V encompass almost 90% of the Saami mtDNAs) (Torroni et al. 1996; Tambets et al. 2004). Thus, although these previous studies have highlighted the role of the Franco-Cantabrian refuge area as a major source of the hunter-gatherer populations that gradually repopulated much of central and northern Europe when climatic conditions began to improve ?15 ky ago, the identification of U5b1b now unequivocally links the maternal gene pool of the ancestral Berbers to the same refuge area and indicates that European hunter-gatherers also moved toward the south and, by crossing the Strait of Gibraltar, contributed their U5b1b, H1, H3, and V mtDNAs to modern North Africans.
In conclusion, this study is a paradigmatic example of the power of genetic inference in human-origin and evolutionary studies. It shows that mtDNA data—in this case, at the highest possible level of molecular resolution—can be used not only to evaluate models proposed by other disciplines and based on the direct survey of ancient material but also to identify previously unknown links between populations and geographic areas. Thus, the study of human genetics directly fosters the development of new research avenues in paleontology, archaeology, linguistics, and history.
This research was supported by CNR-MIUR Genomica Funzionale-Legge 449/97, Fondo Investimenti Ricerca di Base 2001, the Istituto Pasteur Fondazione Cenci Bolognetti, and Progetti Ricerca Interesse Nazionale 2003.
Electronic-Database Information
Accession numbers and URLs for data presented herein are as follows:
Author's Web site, http://ipvgen.unipv.it/docs/projects/torroni_data/torroni_sequences.html (for the complete mtDNA sequences)
GenBank, http://www.ncbi.nlm.nih.gov/Genbank/ (for the complete mtDNA sequences [accession numbers AY882379–AY882417])
Other Sections?
Achilli A, Rengo C, Magri C, Battaglia V, Olivieri A, Scozzari R, Cruciani F, Zeviani M, Briem E, Carelli V, Moral P, Dugoujon JM, Roostalu U, Loogväli EL, Kivisild T, Bandelt HJ, Richards M, Villems R, Santachiara-Benerecetti AS, Semino O, Torroni A (2004) The molecular dissection of mtDNA haplogroup H confirms that the Franco-Cantabrian glacial refuge was a major source for the European gene pool. Am J Hum Genet 75:910–918. [PMC free article] [PubMed]
Andrews RM, Kubacka I, Chinnery PF, Lightowlers RN, Turnbull DM, Howell N (1999) Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nat Genet 23:147. [PubMed] [Cross Ref] doi: 10.1038/13779.
Cann RL, Stoneking M, Wilson AC (1987) Mitochondrial DNA and human evolution. Nature 325:31–36. [PubMed] [Cross Ref] doi: 10.1038/325031a0.
Cavalli-Sforza LL, Menozzi P, Piazza A (1994) The history and geography of human genes. Princeton University Press, Princeton, NJ.
Forster P, Harding R, Torroni A, Bandelt H-J (1996) Origin and evolution of Native American mtDNA variation: a reappraisal. Am J Hum Genet 59:935–945. [PMC free article] [PubMed]
Forster P, Torroni A, Renfrew C, Rohl A (2001) Phylogenetic star contraction applied to Asian and Papuan mtDNA evolution. Mol Biol Evol 18:1864–1881. [PubMed]
Kivisild T, Rootsi S, Metspalu M, Mastana S, Kaldma K, Parik J, Metspalu E, Adojaan M, Tolk HV, Stepanov V, Golge M, Usanga E, Papiha SS, Cinnioglu C, King R, Cavalli-Sforza L, Underhill PA, Villems R (2003) The genetic heritage of the earliest settlers persists both in Indian tribal and caste populations. Am J Hum Genet 72:313–332. [PMC free article] [PubMed]
Mishmar D, Ruiz-Pesini E, Golik P, Macaulay V, Clark AG, Hosseini S, Brandon M, Easley K, Chen E, Brown MD, Sukernik RI, Olckers A, Wallace DC (2003) Natural selection shaped regional mtDNA variation in humans. Proc Natl Acad Sci USA 100:171–176. [PMC free article] [PubMed] [Cross Ref] doi: 10.1073/pnas.0136972100.
Quintana-Murci L, Chaix R, Wells RS, Behar DM, Sayar H, Scozzari R, Rengo C, Al-Zahery N, Semino O, Santachiara-Benerecetti AS, Coppa A, Ayub Q, Mohyuddin A, Tyler-Smith C, Qasim Mehdi S, Torroni A, McElreavey K (2004) Where west meets east: the complex mtDNA landscape of the southwest and Central Asian corridor. Am J Hum Genet 74:827–845. [PMC free article] [PubMed]
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Redhead Natalie Harvey, who was bullied as a child because of her frizzy hair, has become a victim of internet trolls 30 years later.
Ms Harvey was targeted on Twitter and Facebook after a photograph of her aged five was circulated.
The 35-year-old, who had spent £10,000 to change her hairstyle, contacted police about the abuse that brought back memories of being called Orphan Annie.
'They were saying such horrible things about my hair,' said Mrs Harvey, who wears a wig to hide her red locks.
'They must have found a picture on a Facebook gallery from three years ago.
'It was so personal and nasty. It targeted directly at something that has affected me throughout my life.'
One tweet said: 'I can't wait to pull off your wig and reveal your ginger afro hair to everyone'. Another stated: 'Wait until everyone sees your f***ed-up afro hair.'
Mrs Harvey said the bullies in her younger life stopped only after she straightened her hair in a two-hour daily routine.
'When I entered school I would be spat at and called names,' said the mother of one.
'The kids were so cruel and would call me Annie and Yoda and racist remarks.'
Mrs Harvey, from Nottingham, has now deleted her Twitter profile and increased privacy settings on her Facebook page.
'Something has to be done about online security,' she said.
'At least at school I could turn round and see who was insulting me but this is so faceless. The bullies are able to hide behind their keyboards.'

subset: commoncrawl


text: This museum is fun for adults as well! I especially loved the dinosaur skeletons, which are put together as they were when the dinosaurs were alive. Some are huge! The English descriptions were informative and funny at times, like a family of dinosaurs "romantically eating and strolling together." The life-size replicas of dinosaurs outside the museum building need some maintenance... More


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Quiet Books
Quiet Books
{Quiet Book I}
I have a new obsession! Quiet books! Quiet books are fabric books full of fun surprises and activities to keep toddlers and young children *quietly* entertained.
Imagine Our Life :: Loving It - Quiet Books
What's a quiet book? It's a (generally handmade) fabric book full of learning activities.
Imagine Our Life :: Starbucks Quiet Book Page
Imagine Our Life :: Forest Quiet Book Page
Here's the next quiet book page for Jax's book!
Welcome to Antarctica!
Imagine Our Life :: Penguin & Igloo Quiet Book Page


text:
Family Fun or Fitness Magazine as low as $3.99 per Year!
Here are teo nice magazine deals for today.
The first is Family Fun magazine priced at $3.99 per year. Totally worth this because I always get great ideas from this one.
That is for 10 issues so only $.39 per issue. You can buy up to 4 years.
Head over to Discount Mags and use coupon code: myfrugaladventures at checkout.


text:
Quick & easy glitter tutorial for Photoshop! (via Tutorial: How To Make Glitter In Photoshop | Brighter Sides)
I get a lot of questions about how to get pastel colored hair, so I added a little tutorial on my blog! Check it out :)
http:// www.brightersides.com/brightersidesblog/2012/07/how-to-make-pastel-hair-color/
Useful link: Five Tutorials For Styling Long Hair (please reblog it if you like it!)


text:
Hang tight!
Recipe by SAUCYB
"An excellent dessert for after a hearty meal. I have also made the filling with raspberries, strawberries and blueberries, separately or mixed them together for a bumbleberry torte!"
Watch video tips and tricks
1 cup all-purpose flour
1/2 cup margarine
2 tablespoons confectioners' sugar
1 1/2 cups white sugar
3 tablespoons all-purpose flour
3 egg yolks
1/3 cup milk
3 1/2 cups chopped rhubarb
3 egg whites
1/4 cup white sugar
This is the BEST rhubarb torte I've ever tried, bar none! Excellent! Thanks, Donna!
Made this with a regular pie crust and pie pan. It has too much sugar in the filling because it comes out runny.
22 Ratings
This was so pretty! It tasted sublime, let me tell you! Rhubarb is NOT a family favorite & now it has become a beloved, free delish-treat in our home. Great to take to a picnic or any gathering, or just after dinner with the fam. Try it, you won't be disappointed.
My family loves this Rhubarb Torte! I followed the recipe exactly, and it turned out delicious! I usually don't like rhubarb, but this was simply wonderful. I have the second torte in the oven right now as I type. It's an easy recipe, one that my daughters helped me make. The only complaint is that it disappears way too fast. We will definitely make this again. Thanks Saucyb for this recipe!
Sensational rhubarb recipe. I agree with one poster who did not think of it as a torte...but it is awesome nonetheless. I doubled the recipe and made it in a 9 x 13 dish and dusted the top with cinnamon. This is by far the best rhubarb recipe I have ever made!
I wouldn't call this a torte but I would call it the best Rhubarb Meringue Pie I've ever had. And quick and easy in the bargain. I did toss in a bit of cinnamon. And used my own pie crust. I always make up a big batch of pie shells and keep them in the freezer for occasions such as this one - saves time.
This recipe takes me WAAAAY back to my childhood when my mother would make this desert on Sunday's. Talk about a down home midwestern COMFORT FOOD!! I doubled the original as my mother always made hers in a 9x13 pan, but otherwise nothing and I mean NOTHING needs to change!! 5 stars hands down - THANK YOU FOR SHARING THIS RECIPE!!
This torte is not difficult to make. and is delicious. The only problem is it is gone to soon.
* Percent Daily Values are based on a 2,000 calorie diet.
Rhubarb Torte
Serving Size: 1/8 of a recipe Servings Per Recipe: 8 Amount Per Serving Calories: 387 Calories from Fat: 120
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text:
- Report: #760179
Complaint Review: Via Trading
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Via Trading Selling Unsaleable Cosmetic Lots Lynwood, California
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The first lot I got (2009) contained items dated in the 90s and products without labels (white pots with violet something in it). I tried to sell some of the more decent items just to break even. My mistake was keeping mum and not complaining about it.
I must have such a short attention span because I bought from them again the year after that (2010). I bought two lots from them and I will be fair and say that one lot was good and it did well, but the other one was again a really bad lot. There were no expiration dates on it but just the smell you get after you open the box tells you that they have long been expired. I called to complain about it and I didn't really appreciate how my account manager (at that time), Luis, handled my complaint. He said that with the price I paid I shouldn't really expect much. Two things that came to my mind when he said that: 1) I have bought cheaper items in the past (10-15 cents each) from other liquidators but never had that problem; 2) He hinted at an awareness that the lot is not a good one. I asked to speak with his manager. I spoke with Orlando and he gave me a store credit because he said they don't give refunds. The store credit has some interesting conditions, mind you: We will honor a store credit of $XXX dollars. Please note that depending on the order the amount will vary. We may or may not be able to apply to full credit on one order. But we will honor the full amount in multiple orders if necessary. This means I have to return again and again and again to finally get my money back.
With the store credit given to me, I had no choice but to take my business to their company again around May of this year. I found something I wanted to buy and I have made peace with the fact that only a fraction of my store credit will be accepted. I called my new account manager, Shaun, to ask him how much I have to purchase to get the maximum amount of the store credit and at least to know what my best options were. Apparently, new doesn't mean better. This guy just didn't know how to listen. I explained to him in so many words, in the clearest of ways what I wanted to happen and he didn't understand (or he refused to understand?). In my frustration, I just decided to call the next day and asked to speak to a Senior Manager. I got Jenny and she understood me from the get go and I was able to finalize my order. She even gave me the full store credit even with just one transaction and suggested lots which I might be interested in.
I bought two lots: one was a mixed lot and the other was a lot of one item of the same kind. I took time of going through the mixed lot to check for damaged and expired items. For the second lot, I just pulled a couple of items, saw they're ok, and didn't bother going through the rest before I packed them to send it to my country..which was my mistake.
When it arrived and I did a more thorough inventory and went through the items from the 2nd lot I saw that there's MOLD on the make up! It was just disgusting, I couldn't believe it. I was hoping that it's just a fraction of the lot but after I went through them one by one more than 50% had mold. I didn't bother selling the rest which didn't have mold for fear that my customers would have a bad reaction to it and sue me. I didn't go to them anymore because the few times I went to them to complain about something I just felt they weren't receptive to it until you get to a Senior Manager. And besides, what are they going to give me, their joke of a store credit? To lure me to buy from them again? No, thanks.
So my tip, search further..find other liquidators. I do my business with two other companies and so far I'm happy with them. I have to say though that this is only in reference to their cosmetics, I don't know anything about their other items.
This report was posted on Ripoff Report on 08/03/2011 06:59 AM and is a permanent record located here: http://www.ripoffreport.com/r/Via-Trading/Lynwood-California-90262/Via-Trading-Selling-Unsaleable-Cosmetic-Lots-Lynwood-California-760179. The posting time indicated is Arizona local time. Arizona does not observe daylight savings so the post time may be Mountain or Pacific depending on the time of year.
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text:
Manoj Bajpayee back on TV
Varinder Chawla
Mumbai: Actor Manoj Bajpayee, who was quite active on the small-screen before making it big in filmdom, will again be seen in a special episode of TV series 'Hum Ne Li-Hai Shapath'.
"Shooting for an episode of series '... Shapath' where my character from 'Special Chabbis' will feature," the 43-year-old tweeted.
The series comes on Life OK and when approached, the channel confirmed the news to IANS.
In the beginning of his career, Manoj worked in Tigmanshu Dhulia's TV series 'Hum Bambai Nahin Jayenge' and 'Swaabhimaan' and after the success of 'Satya', he shifted his focus to the big screen.
Last year, he was seen in much appreciated films like Anurag Kashyap's crime thriller 'Gangs of Wasseypur', Prakash Jha's 'Chakravyuh' about Maoists problem in the country, and historical drama 'Chittagong'.
Manoj is playing a CBI agent in his forthcoming film 'Special Chabbis'.
The heist drama directed by Neeraj Pandey, also stars Akshay Kumar and Anupam Kher in the key roles. Kajal Aggarwal and Jimmy Shergill are also part of the impressive cast.
The film releases on February 8.
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Bergen County GOP hoping party unity can win elections
For the first time in several years, Bergen County Republicans will not have an internal fight over who gets the party line for county-wide offices.
As of Friday, the internal party filing deadline, only the three incumbent freeholders Maura DeNicola, John Felice and John Mitchell had declared themselves candidates. Sheriff Michael Saudino also had no Republican opposition.
"As long as as I can remember, there have been these convention battles," Republican Party Chairman Bob Yudin said Saturday. "For the first time, we're united."
There will be GOP convention contests, however, for the state assembly seats in Districts 36 and 39 and for a state senate seat in District 38.
Embattled Republican Assemblyman Bob Schroeder, R-Washington Township, did not file for the party-line designation in District 39.
Schroeder is currently facing an indictment charging him with theft from people who loaned him money and with writing bad checks to creditors.
In his absence, five people have declared themselves candidates for the two assembly seats in the district, which includes parts of northern Bergen and Passaic counties.
Besides incumbent Holly Schepisi of River Vale, the declared candidates include Old Tappan GOP municipal chair Bob Auth, former Freeholder Robert Hermansen, Saddle River Council President Karen Mastriano and Old Tappan Mayor Victor Polce.
In District 36, four Republicans are running for the party line for two assembly seats currently held by Democrats. They are Lynn DeLucia of Cliffside Park, James Keyes of Ridgefield Park, Foster Lowe, the GOP municipal chair of Little Ferry and Rosina Romano, former South Hackensack mayor and outgoing Bergen County elections commissioner.
Ryan Fitzhenry of North Arlington is seeking the GOP nod for the state Senate seat currently held by Sen. Paul Sarlo, D-Wood Ridge.


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Weight-loss success story: Chantel Hobbs
Image 1 of 5
Chantel Hobbs: before and after weight loss
"I always joke that maybe my weight was God's protection," Chantel Hobbs says.
"Maybe if I looked the way I look today, I would have had a whole different life and maybe it wouldn't be the life that's enabled me to do the cool stuff that I'm able to do now. The fulfilling stuff, the stuff that's really what life's about. Helping others and being passionate." |
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text:
rocknbil - 2:52 am on Dec 5, 2009 (gmt 0)
I still have a WACOM with an outline of Homer Simpson permanently ground into the translucent tracing cover. And she had her own computer too, our toys will still always be better. "Let's do this on Dad's computer, just in case something breaks."
HAHA this is great.


text:
Monoi Tiare Tahiti Monoi Tiiki Tahiti Coconut Oil -- 4 fl oz
Great smell -feels light and lovely on skin
It solidifies if is not in a warm room but that is even better because the only problem -when is on its liquid state - is the bottle as if you're not careful you can pour too much at once...other than that---I am loving its fragrance and its smooth feel on my skin....Long lasting too! you need little to achieve your results.
October 27, 2013
I use this for suntan oil and after shower
I love the smell, makes my skin really soft, better than suntan oil.
August 19, 2013
smells nice
if you like the scent of gardenia, you'll like this.
i wouldn't buy it again because it's too difficult to get
out of the bottle once it's hardened. which is why i
only gave it 2 stars.
July 25, 2013
Awesome product
This is the second time I have ordered this oil, the smell is wonderful without being over powering and it is truly moisterizing. Beware if you don't like the oily feeling, I usually sit on a towel for awile after applying to spare my sofa fabric. It's well worth the effort though.
June 20, 2013
Good, but Not Quite Great
I do like this product, but I'm not in love with it. First, I wish it came in a larger bottle. It would be a product that I would have to use sparingly after showering because it wouldn't last long. It does feel amazing! I also used it to oil my scalp one evening (I have natural hair) and my scalp wasn't a fan. It flaked really bad. I tried it again later and it did the same thing. I do like it as a deep conditioner mixed with other oils. The smell is intoxicating!
May 6, 2013


text:
Distfile availability status for www/mod_antiloris
Maintainer: email@example.com
Status codes:
- numeric values represent RFC 2616 status codes
- NXDOMAIN means that the hostname could not be resolved
- network timeouts result in code 500
It is possible that a failed check could work now. Status codes between 500-599 are transient errors and the status you see represents the period of time when the distfile was checked.
Ports that set DEPRECATED, FETCH_CMD, FETCH_ENV, FETCH_BEFORE_ARGS, FETCH_AFTER_ARGS, or have a do-fetch: target are simply skipped.
All the tables have clickable headers that sort the table by the clicked column.
show bad only, cvsweb, other ports from this maintainerURL | Checked | Last OK | Status |
ftp://ftp.monshouwer.eu/pub/linux/mod_antiloris/mod_antiloris-0.4.tar.bz2 | 2014-03-07, 00:49:39 | 200 | |
http://modules.apache.org/search.php?id=1783 | 2014-03-07, 05:26:14 | 2013-05-21, 01:48:48 | 404 |


text:
Protein-Protein Interaction on Lysozyme Crystallization Revealed by Rotational Diffusion Analysis Biophysical Journal, Volume 94, Issue 11, 1 June 2008, Pages 4484-4492 Daisuke Takahashi, Etsuko Nishimoto, Tadashi Murase and Shoji Yamashita Abstract Intermolecular interactions between protein molecules diffusing in various environments underlie many biological processes as well as control protein crystallization, which is a crucial step in x-ray protein structure determinations. Protein interactions were investigated through protein rotational diffusion analysis. First, it was confirmed that tetragonal lysozyme crystals containing fluorescein-tagged lysozyme were successfully formed with the same morphology as that of native protein. Using this nondisruptive fluorescent tracer system, we characterized the effects of sodium chloride and ammonium sulfate concentrations on lysozyme-lysozyme interactions by steady-state and time-resolved fluorescence anisotropy measurements and the introduction of a novel interaction parameter, krot. The results suggested that the specific attractive interaction, which was reflected in the retardation of the protein rotational diffusion, was induced depending on the salt type and its concentration. The change in the attractive interactions also correlated with the crystallization/precipitation behavior of lysozyme. Moreover, we discuss the validity of our rotational diffusion analysis through comparison with the osmotic second virial coefficient, B22, previously reported for lysozyme and those estimated from krot. Abstract | Full Text | PDF (363 kb) |
Membrane Fluidity and Lipid Order in Ternary Giant Unilamellar Vesicles Using a New Bodipy-Cholesterol Derivative Biophysical Journal, Volume 96, Issue 7, 8 April 2009, Pages 2696-2708 Florly S. Ariola, Zaiguo Li, Christine Cornejo, Robert Bittman and Ahmed A. Heikal Abstract Cholesterol-rich, liquid-ordered (Lo) domains are believed to be biologically relevant, and yet detailed knowledge about them, especially in live cells under physiological conditions, is elusive. Although these domains have been observed in model membranes, understanding cholesterol-lipid interactions at the molecular level, under controlled lipid mixing, remains a challenge. Further, although there are a number of fluorescent lipid analogs that partition into liquid-disordered (Ld) domains, the number of such analogs with a high affinity for biologically relevant Lo domains is limited. Here, we use a new Bodipy-labeled cholesterol (Bdp-Chol) derivative to investigate membrane fluidity, lipid order, and partitioning in various lipid phases in giant unilamellar vesicles (GUVs) as a model system. GUVs were prepared from mixtures of various molar fractions of dioleoylphosphatidylcholine, cholesterol, and egg sphingomyelin. The Ld phase domains were also labeled with 1,1′-didodecyl-3,3,3′,3′-tetramethylindocarbocyanine (DiI-C12) for comparison. Two-photon fluorescence lifetime and anisotropy imaging of Bdp-Chol are sensitive to lipid phase domains in GUVs. The fluorescence lifetime of Bdp-Chol in liquid-disordered, single-phase GUVs is 5.50 ± 0.08 ns, compared with 4.1 ± 0.4 ns in the presence of DiI-C12. The observed reduction of fluorescence lifetime is attributed to Förster resonance energy transfer between Bdp-Chol (a donor) and DiI-C12 (an acceptor) with an estimated efficiency of 0.25 and donor-acceptor distance of 2.6 ± 0.2 nm. These results also indicate preferential partitioning (Kp = 1.88) of Bdp-Chol into the Lo phase. One-photon, time-resolved fluorescence anisotropy of Bdp-Chol decays as a triexponential in the lipid bilayer with an average rotational diffusion coefficient, lipid order parameter, and membrane fluidity that are sensitive to phase domains. The translational diffusion coefficient of Bdp-Chol, as measured using fluorescence correlation spectroscopy, is (7.4 ± 0.3) × 10−8 cm2/s and (5.0 ± 0.2) × 10−8 cm2/s in the Ld and Lo phases, respectively. Experimental translational/rotational diffusion coefficient ratios are compared with theoretical predictions using the hydrodynamic model (Saffman-Delbrück). The results suggest that Bdp-Chol is likely to form a complex with other lipid molecules during its macroscopic diffusion in GUV lipid bilayers at room temperature. Our integrated, multiscale results demonstrate the potential of this cholesterol analog for studying lipid-lipid interactions, lipid order, and membrane fluidity of biologically relevant Lo domains. Abstract | Full Text | PDF (963 kb) |
Quantitative Characterization of the Large-Scale Association of ErbB1 and ErbB2 by Flow Cytometric Homo-FRET Measurements Biophysical Journal, Volume 95, Issue 4, 15 August 2008, Pages 2086-2096 Ágnes Szabó, Gábor Horváth, János Szöllősi and Peter Nagy Abstract The association of receptor tyrosine kinases is a key step in the initiation of growth factor-mediated signaling. Although the ligand-induced dimerization of inactive, monomeric receptors was the central dogma of receptor tyrosine kinase activation for decades, the existence of larger oligomers is now accepted. Both homoassociations and heteroassociations are of extreme importance in the epidermal growth factor (EGF) receptor family, leading to diverse and robust signaling. We present a statistically reliable, flow-cytometric homo-fluorescence resonance energy transfer method for the quantitative characterization of large-scale receptor clusters. We assumed that a fraction of a certain protein species is monomeric, whereas the rest are present in homoclusters of N-mers. We measured fluorescence anisotropy as a function of the saturation of fluorescent antibody binding, and fitted the model to the anisotropy data yielding the fraction of monomers and the cluster size. We found that ErbB2 formed larger homoclusters than ErbB1. Stimulation with EGF and heregulin led to a decrease in ErbB2 homocluster size, whereas ErbB1 homoclusters became larger after EGF stimulation. The activation level of ErbB2 was inversely proportional to its homocluster size. We conclude that homoclusters of ErbB1 and ErbB2 behave in a fundamentally different way. Whereas huge ErbB2 clusters serve as a reservoir of inactive coreceptors and dissociate upon stimulation, small ErbB1 homoclusters form higher-order oligomers after ligand binding. Abstract | Full Text | PDF (383 kb) |
Copyright © 2010 Biophysical Society All rights reserved.
Biophysical Journal, Volume 98, Issue 12, 2886-2894, 16 June 2010
Alf Honigmann†, Claudius Walter‡, Frank Erdmann†, Christian Eggeling§ and Richard Wagner†, ,
† Universität Osnabrück, Fachbereich Biologie/Chemie, Osnabrück, Germany
‡ Ionovation GmbH, Osnabrück, Germany
§ Max-Planck-Institut für Biophysikalische Chemie, Abteilung NanoBiophotonik, Göttingen, Germany
Artificial lipid membranes are widely used as a model system to study single ion channel activity using electrophysiological techniques. In this study, we characterize the properties of the artificial bilayer system with respect to its dynamics of lipid phase separation using single-molecule fluorescence fluctuation and electrophysiological techniques. We determined the rotational motions of fluorescently labeled lipids on the nanosecond timescale using confocal time-resolved anisotropy to probe the microscopic viscosity of the membrane. Simultaneously, long-range mobility was investigated by the lateral diffusion of the lipids using fluorescence correlation spectroscopy. Depending on the solvent used for membrane preparation, lateral diffusion coefficients in the range Dlat = 10–25 μm2/s and rotational diffusion coefficients ranging from Drot = 2.8 − 1.4 × 107 s−1 were measured in pure liquid-disordered (Ld) membranes. In ternary mixtures containing saturated and unsaturated phospholipids and cholesterol, liquid-ordered (Lo) domains segregated from the Ld phase at 23°C. The lateral mobility of lipids in Lo domains was around eightfold lower compared to those in the Ld phase, whereas the rotational mobility decreased by a factor of 1.5. Burst-integrated steady-state anisotropy histograms, as well as anisotropy imaging, were used to visualize the rotational mobility of lipid probes in phase-separated bilayers. These experiments and fluorescence correlation spectroscopy measurements at different focal diameters indicated a heterogeneous microenvironment in the Lo phase. Finally, we demonstrate the potential of the optoelectro setup to study the influence of lipid domains on the electrophysiological properties of ion channels. We found that the electrophysiological activity of gramicidin A (gA), a well-characterized ion-channel-forming peptide, was related to lipid-domain partitioning. During liquid-liquid phase separation, gA was largely excluded from Lo domains. Simultaneously, the number of electrically active gA dimers increased due to the increased surface density of gA in the Ld phase.


text:
Post Content
Weekly Report: Download Weekly Report 2_18_10 (Download PDF Weekly Report 2_18_10)
As you can see in this week's report, the level of flu-like illness in the state has decreased to an even lower level than what is expected for this time of year. While we would normally see seasonal flu-like illness begin to increase at this point and then peaking in late-February or Match, flu-like illness continues to remain at low levels. Nevertheless, we encourage everyone to get their H1N1 vaccine – find a clinic near you at http://flu.masspro.org or contact your regular health care provider.
One thought on "Weekly Flu Report: February 18, 2010"
Residents of Boston can also call the Mayor's Health Line at 617-534-5050 for an updated list of free flu clinics. These are not always updated or posted on flu.masspro.org.


text:
Ottawa gives Malaysian bid for Progress more scrutiny
TORONTO/CALGARY, Oct 5 (Reuters) – The Canadian government
has extended by two weeks its review of a C$5.2 billion ($5.3
billion) bid by Malaysian state oil company Petronas to take
over Progress Energy Resources Corp as the country's
focus on foreign moves to buy Canadian resource companies
The unexpected delay comes as Ottawa also vets a $15.1
billion offer for Nexen Inc by CNOOC Ltd, the
Chinese state-controlled company, a deal that has been slammed
both by Canada's main opposition party and from some within
Conservative Prime Minister Stephen Harper's own government.
Canada extends review of Petronas bid for Progress Energy, which is a little weird http://t.co/vl701Ce4 #cnooc #nexen
@dblacombe Depends on the context
Canada's opposition NDP says Ottawa must nix CNOOC bid for Nexen, citing "lack of transparency", "alarming no of unanswered questions"
@sunrickbell And I'm sure you were at the very front of that one!
Just new in the corner office, #Enbridge's CEO floats some light #oil pipeline plans http://t.co/PTNjcpfO #ngp #cdnpoli
"@ReutersCanada: #Canadian government rejects public consultations on Nexen bid http://t.co/lyxxqNsL #cdnpoli #oil #China"
Enbridge CEO floats new light oil pipeline plans
CALGARY, Alberta, Oct 3 (Reuters) – Enbridge Inc's
new chief executive kicked off his tenure as head of the main
transporter of Canadian oil exports on Wednesday with new ideas
to get growing volumes of light crude to Eastern markets and
prospects for richer earnings.
Al Monaco, who took over as CEO on Monday, said the boom in
light oil production from sources like the North Dakota Bakken
has drastically shifted North America's supply outlook, forcing
deep price discounts for supplies not linked to international
Brent crude pricing and prompting the need for new pipeline
RT "@reutersLjungg: Don't rubber-stamp CNOOC's bid for #Nexen, #Canada opposition urges http://t.co/YHoxJPmu #China #oil"
Total content with Canadian oil sands pace
CALGARY, Alberta, Oct 2 (Reuters) – Total SA is
content with the pace of developing its Canadian oil sands
assets even as Suncor Energy Inc, its joint venture
partner, said it was in no rush to bring a host of
multibillion-dollar projects on line, an executive said on
Jean-Michel Gires, head of Total's Canadian unit, said the
French oil major is not looking to bulk up on more northern
Alberta oil sands assets as it and Suncor move forward with
studying two mines and an upgrading plant.


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We are CAPS certified Home Modification Specialists focused on bringing comfort, safety and a sense of independence for those wishing to stay in their home. Live Well provides... Read More
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Garage Designs of St. Louis helps families get organized, homeowners improve their properties, and car lovers create a special space for their "baby" with complete garage... Read More
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Petra Masonry is a growing company dedicated to serving our customers with quality stone, brick and block work. We have experience with both natural stone and manufactured... Read More
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security systems integrator, specializing in burglar and fire alarm systems, access control, CCTV, the latest digital video recording (DVR), metal detectors, IP video,... Read More
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If you are looking for the best home inspector in St. Louis look no further! We hand select the best home inspectors in every area of the United States so you don't have to. Each... Read More
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The parties, the shopping, the celebrity pals – catch up with the 29-year-old Alone in the Dark star. By Beth Lipton
Credit: ginsburg-spaly/x17
Updated: Tuesday Feb 01, 2005 | 06:00 AM EST
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Reid helps pal Lindsay Lohan celebrate her 18th birthday with a shopping trip in Beverly Hills last July. Later that night, Reid was among the celeb guests at Lohan's party at L.A. club Avalon.


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AbstractAngiotensin (Ang) II, the main effector of the renin–angiotensin system (RAS), is one of the major mediators of vascular remodeling in hypertension. Besides being a potent vasoactive peptide, Ang II exerts proinflammatory effects on the vasculature by inducing integrins, adhesion molecules, cytokines and growth and profibrotic mediators through activation of redox-sensitive pathways and transcription factors. Clinical findings suggest that inflammation participates in the mechanisms involved in the pathophysiology of hypertension and its complications. Antagonists of the RAS have been shown to exert cardiovascular protection, in part through their vascular anti-inflammatory effects. However, further studies are needed to better understand whether inflammatory biomarkers might be clinically useful for cardiovascular risk stratification and whether targeting inflammation pharmacologically will improve cardiovascular outcomes beyond blood pressure reduction. The present review addresses recent findings regarding the pathophysiology of vascular inflammation in hypertension, focusing specifically on the role of Ang II.
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Posts tagged texatron
'Texatron' initiative bringing indie arcade games to Austin
The Winnitron arcade machine concept -- that of an arcade machine loaded up with exclusive indie games -- is migrating south. The Austin, TX-based Juegos Rancheros collective announced plans to bring the concept to Austin as the Texatron. Rather than a single machine, the long-term plans involve...
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Sydney Penny to Leave All My Children... Again
by Matt Richenthal at .Sydney Penny is once again leaving her role as Julia on All My Children.
She originally portrayed the role from 1993 to 1996, returning a few times before coming back on contract in 2005. The plan right now is the following: Once Kathy is revealed to be actually be Katie, Julia will be written out of the show.
Will you miss Penny on All My Children?
Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.
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How much coconut?!!
Millionaire Pie Recipe
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Yield: 1 serving
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- 1 graham cracker crust
- 1 package(s) 8 pz cream cheese
- 1/2 cup(s) sugar
- 1 can(s) 8oz crushed pineapple
- 1 cup(s) finely chopped pecans
- 1 container(s) 8oz cool whip
- Cream together your cream cheese and sugar with a hand mixer for 3-4 minutes. Now add in the pineapple, coconut , and pecans and mix together very well. Now fold in half of the whipped topping and mix well together. Pour into the graham cracker pie shell.
- Take the other half of the cool whip and place it on top of the pie. Toast the tablespoon of reserved coconut to golden brown under your broiler and sprinkle it on top of your pie for garnish. Cover the pie and place back in the freezer. When ready to serve let the pie thaw just enough to be able to be able to cut your pie.
- Serve your pie on saucers or pie plates that you have had in the freezer for at least 4 hours and it will work better if they have been in the freezer over night. You can if you wish garnish the top of your pie with a maraschino cherry .
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Wedding Crashers (2005)
Average Rating: 6.8/10
Reviews Counted: 182
Fresh: 137 | Rotten: 45
Wedding Crashers is both raunchy and sweet, and features top-notch comic performances from Vince Vaughn and Owen Wilson.
Average Rating: 6.8/10
Critic Reviews: 45
Fresh: 32 | Rotten: 13
Wedding Crashers is both raunchy and sweet, and features top-notch comic performances from Vince Vaughn and Owen Wilson.
liked it
Average Rating: 3.5/5
User Ratings: 32,948,975
Movie Info
Two guys find out the hard way that sneaking into the wrong party can cause serious problems in this comedy. Jeremy Klein (Vince Vaughn) and John Beckwith (Owen Wilson) are a pair of longtime friends who work for a law firm, helping contentious couples mediate their divorces. Their job has given them a cynical attitude about marriage, and as a hobby each weekend the two make a point of crashing weddings reception, where they load up on free food and booze and try their luck at seducing the
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John Beckwith -
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William Cleary -
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Claire Cleary -
Jane Seymour
Kathleen Cleary -
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All Critics (182) | Top Critics (45) | Fresh (137) | Rotten (45) | DVD (35)
Vince Vaughn and Owen Wilson are enormously funny.
Sharply honed, if often raunchy.
It's good, but it's no Anchorman.
Sometimes a movie comedy just clicks. Welcome to one of those times.
The most exhilarating entertainment to emerge this year from the failed, forlorn factory town of Hollywood, largely because of Owen Wilson and Vince Vaughn, the best high-low comedy team since the hey-hey days of Paul Newman and Robert Redford.
It produces more laughs per minute than any film so far this year.
The Frat Pack goes from strength to strength in a robust romp that's only marred by the director's apparent inability to say "Cut!"
A bawdy summer comedy for adults and mature teens, this movie features rapid-fire dialogue and sincere affection between best-friend leads and strong chemistry between the actors who portray them.
What should've been an absolutely raucous and no-holds-barred lusty farce is nothing but lame-ass, safe, predictable, lowest common denominator, no-laffs garbage
With great acting, hilarious gags, and great writing, it actually lives up to the hype.
Vince Vaughn commits rampant acts of comic zeal while the script around him crumbles in a movie that loses its thrust like a cat caught in traffic.
The two actors make a good contrasting team and bring an energy to the story that many romantic comedies lack.
The likes of the sneakily subversive Wilson and Vaughn deserve better... but this is darn close to a perfect showcase for what they can do, and how much better they do it together.
Guys will have a few laughs but this certainly won't have the rewatch value of the likes of Old School or the Pie movies.
Unless you check your political correctness at the box office, expect to be offended.
...suffers from a third act that's painfully overlong and needlessly dramatic.
The film's best element is the inspired casting of Vince Vaughn and Owen Wilson; their easy repartee helps to grease over the film's shortcomings.
This is a major blast of fast-talking, loopily plotted, politically incorrect film fun.
At this point, Wilson has his laconic surfer-dude persona down pat, so it's Vaughn who really surprises as the hilariously spastic side of the partnership.
There is a considerable fun factor in the movie with its wedding party atmosphere, lively music, dancing and Vince Vaughn's energetic performance.
...the film works so well, on a variety of levels.
This is a must-attend event.
Of the two stars, Vaughn definitely gets the funnier lines, reducing Wilson almost to the role of straight man. Isla Fisher though, manages to steal every scene that she's in, away from both of them.
Audience Reviews for Wedding Crashers
Full review coming to themoviefreakblog.com on August 3, 2013.
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Movies Like Wedding Crashers
- Himself: Hey, I'm Kelly. I've got a compulsion.
- Jeremy Grey: She's fit for a strait-jacket. This broad's fucked three ways towards the weekend. But you know what, Father? I dig it! It turns me on.
- John Beckwith: Get up, you're making us look like pussies.
- Jeremy Grey: If I had any air in my lungs I'd scream at you.
- Jeremy Grey: I'm sorry. I'm not sorry. Okay? I'm not gonna apologize, I'm a cocksman!
- Jeremy Grey: [on the phone with Gloria] Bunch those panties up into a little ball, and put that little ball right in your mouth. Oh, yeah...
- Sack: Claire, you get your fucking ass on that altar right now!
- Chazz Reinhold: Wow, we're getting a great preview of what marriage is gonna be like with Ike Turner over here.
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Mars Tethered Sample Return (1989)
- 04.27.13
- Categories: Beyond Apollo, Science Blogs
Throughout the 1980s, engineers at the Jet Propulsion Laboratory in Pasadena, California, and at NASA's Johnson Space Center in Houston, Texas, worked with planetary scientists and contractor engineers to develop what came to be called a Mars Rover Sample Return (MRSR) mission for the 1990s. The MRSR mission would have seen a sophisticated large rover land on Mars and roll over the surface for tens or even hundreds of kilometers. A Mars-orbiting satellite with a massive telescopic camera for traverse route imaging would have helped engineers and scientists select the safest, most scientifically productive path across Mars's surface, and a powerful communications relay orbiter would have kept controllers on Earth in constant touch with the rover.
The rover, which might have weighed several tons, would have carried a complex suite of sensors and tools to enable collection of a suite of geologic samples representative of a large area of Mars. The samples would have been sealed in a container, transferred to an ascent vehicle, and launched into Mars orbit, where they would have been handed off to an orbiting Earth Return Vehicle (ERV). The ERV would have installed the sample container in an aeroshell and launched it to Earth, where it would have aerobraked into orbit for Space Shuttle or Space Tug recovery. Some plans called for a separate quarantine space station for preliminary sample analysis.
The mission was very complex, with many opportunities for malfunctions, so to help to ensure its success all MRSR vehicles would have been redundant. This would have required multiple Space Shuttle or expendable rocket launches and possibly assembly at NASA's Earth-orbiting Space Station. It is not to surprising, then, that a 1988 independent cost estimate placed the MRSR mission's cost at $13 billion. Including the precursor orbiter-rover-penetrator mission some declared to be necessary would have driven the cost of returning a kilogram or two of Mars to Earth even higher.
The 1980s MRSR debacle impressed on many the idea that automated return of Mars samples must be very costly. Before the 1980s were out, however, groups within JPL and JSC and their contractors, as well as independent scientists and engineers, sought less costly methods of sampling Mars. Most sought to eliminate the large rover in favor of a lander that would collect samples only within reach of its robot arm. At least one sought to eliminate even the lander.
In a brief paper in the April 1989 issue of Journal of Spacecraft and Rockets, Alan Stern, a researcher at the Laboratory for Atmospheric and Space Physics at the University of Colorado in Boulder, noted that scientists using data from the Mariner 9 orbiter – which arrived at Mars on 14 November 1971 during a dense, long-lasting, global martian dust storm – had observed that seasonal dust storms loft fine-grained material from Mars's surface up to 60 kilometers into its thin atmosphere. The twin Viking Orbiters also observed high-altitude dust. Stern then proposed a novel, bare-bones approach to Mars sample collection: that a Mars-orbiting spacecraft lower a "collection platform" on a sturdy tether to an altitude of 50 kilometers above the surface during a seasonal dust storm.
Stern estimated that his Mars Tethered Sample Return scheme could gather a 100-gram sample of airborne Mars dust in 55 hours. He acknowledged that atmospheric drag on the tether and collection platform would slow the Mars orbiter, causing it to lose orbital altitude. He calculated, however, that its altitude would decrease at a rate of only five kilometers per kilogram of dust collected. Tether and platform erosion by high-velocity dust impacts might be of greater consequence, he wrote.
With sample collection complete, the orbiter would reel in the platform and dust sample and load the latter into a reentry capsule. An ERV would then launch the capsule out of Mars orbit to waiting scientists on Earth.
Stern's Mars Tethered Sample Return proposal did not influence NASA Mars Sample Return planning. Partly this was because its "random sample" approach could not permit material to be collected from specific known sites on Mars. Instead, it would collect dust grains that had potentially blown from sites all over the planet. Without knowing where the samples originated, researchers could not use them to characterize specific geologic units on Mars.
In the nearly quarter-century since 1989, however, the science and technology of small-particle sample collection and analysis have made great strides. Particles the Stardust comet sample-returner captured intact from Comet Wild 2 in January 2004 and returned to Earth in January 2006, for example, have yielded invaluable data about the nature of comets and the regions of space through which they travel. Given the large quantity of geologic data Mars orbiter and lander spacecraft have collected since Stern wrote his paper – data that could provide at least a general context for very small, randomly collected samples – it seems possible that, were it to be carried out now, his proposed Mars Tethered Sample Return mission could yield a Mars sample with a value at least commensurate with its likely low cost.
"Mars Tethered Sample Return, S. Alan Stern, Journal of Spacecraft and Rockets, Vol. 26, No. 4, April 1989, pp. 294-296.
I research and write about the history of space exploration and space technology with an emphasis on missions and programs planned but not flown (that is, the vast majority of them). My posts are based on more than 30 years of research into spaceflight history. I provide plenty of historical context. I also include lots of crunchy technical details to help the reader envision what might have been - and, in many cases, what might yet be.
Read more by David S. F. Portree
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The vestibular system enables us to perceive self-motion and to keep our balance even when we are in complete darkness. Understanding its dynamics is important, e.g. for motion simulation, virtual reality environments or patients suffering from vestibular problems. We investigate vestibular perception (direction detection thresholds, reaction times) and describe it with physiologically plausible models which are based on the neuronal activity elicited by vestibular stimulation.
Electrically evoked illusory Self-motion
Normally the vestibular system responds to self-motion by modulating the firing rate of the afferent fibers. However, additional factors might influence the self-motion perception and thereby generate illusory movements. An example of this is provided by Galvanic Vestibular Stimulation (GVS): a transcutaneous electrical stimulus applied over the mastoid process that evokes an illusion of physical roll.
Human Control Behavior in Closed-Loop Tasks
We investigate human closed-loop control strategies by considering behaviour at a skill-based level, which involves elementary human information processing and basic control tasks. By employing multiloop modelling techniques to describe human cognitive behaviour in closed-loop control tasks, we can distinguish between different processing paths in the measured human response.
Mechanisms of biodynamic interference
Inside a moving vehicle humans are subjected to accelerations. These accelerations may interfere with manual control tasks in several ways, reducing manual control performance and thus reducing control accuracy and safety for a large range of vehicles. We measure and model these biodynamic interferences in order to understand and mitigate these effects.
Neuroimaging during self-motion
To better understand brain activity associated with self-motion perception without relying on inducing the perception of self-motion using visual information alone (vection), we combine Electroencephalography (EEG) while physically moving people using a Stewart motion platform.


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Last updated: Tue Mar 11 11:07:57 EDT 2014
CVE Publication rate: 15.1
NVD provides four mailing lists to the public. For information and subscription instructions please visit NVD Mailing Lists
Vulnerability Workload Index: 6.66
The App Container feature in the kernel-mode drivers in Microsoft Windows 8, Windows Server 2012, and Windows RT allows remote attackers to bypass intended access restrictions and obtain sensitive information from a different container via a Trojan horse application, aka "App Container Elevation of Privilege Vulnerability."
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A former inspector for a company that did work on TransCanada Corp. 's original Keystone pipeline is accusing the Calgary-based company of a cavalier disregard for the environment.
Mike Klink was an engineer for construction company Bechtel Corp., a contractor that worked on the first portion of the Keystone pipeline that carries Alberta oil sands crude to refineries in the U.S. Midwest. It was completed in 2010; the controversial Keystone XL would extend that pipeline to Gulf Coast refineries.
In an opinion piece published over the weekend in Nebraska's Lincoln Journal Star, the 59-year-old Mr. Klink says he raised a series of concerns about alleged substandard materials and poor craftsmanship along the Keystone pipeline.
The Indiana man says he was fired by Bechtel as a result, and filed a complaint about his dismissal with the U.S. Department of Labour in March 2010. In his formal complaint, also sent to the U.S. Office of Whistleblower Protection Program, Mr. Klink says the company began treating him as a "problem inspector" culminating in one supervisor angrily ordering him to quit before he got fired.
"Let's be clear — I am an engineer; I am not telling you we shouldn't build pipelines," he wrote in the Nebraska newspaper.
"We just should not build this one."
His job as an inspector, Mr. Klink said, involved monitoring the construction of pump stations along the first Keystone pipeline.
"I am coming forward because my kids encouraged me to tell the truth about what was done and covered up," he wrote. "When I last raised concerns about corners being cut, I lost my job — but people along the Keystone XL pathway have a lot more to lose if this project moves forward with the same shoddy work."
TransCanada spokesman Terry Cunha disputed Mr. Klink's assertions, saying he "appears to have made a number of allegations against his previous employer and others, none of which have been proven."
Mr. Cunha added that whenever safety concerns are raised by inspectors, TransCanada takes them seriously.
"If a concern is raised, we investigate immediately. If corrective action is required, we act .... Safety is top priority for us. We monitor our Keystone pipeline system through a centralized high-tech centre 24 hours a day, 365 days a year."
Mr. Klink says, however, that he noticed substandard building materials, construction methods and safety standards as he inspected the pipeline.
"Cheap foreign steel that cracked when workers tried to weld it, foundations for pump stations that you would never consider using in your own home, fudged safety tests, Bechtel staffers explaining away leaks during pressure tests as 'not too bad,' shortcuts on the steel and rebar that are essential for safe pipeline operation and siting of facilities on completely inappropriate spots like wetlands," he wrote.
He said that he shared his concerns with his bosses, who passed them along to "the bigwigs at TransCanada, but nothing changed. TransCanada didn't appear to care."
Keystone remains in the spotlight in the U.S. capital after Republicans succeeded in having a provision inserted into legislation to extend payroll tax cuts and unemployment insurance benefits to Americans hard-hit by tough economic times.
The measure would force the Obama administration to make a decision on Keystone XL within 60 days. White House officials and Democrats say the provision has all but killed the pipeline since a thorough review of a new route for Keystone XL — around a crucial aquifer in Nebraska — cannot be conducted in such a short time period.
Security | Price | Change | |
TRP-T TransCanada Corp. | 49.30 |
-0.23 -0.464 % |
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Wed Aug 1, 2012 10:47 am
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Wed Aug 1, 2012 10:47 am Ravens waived QB John Brantley.
Fantasy Source Spin: It's a bad sign that Brantley couldn't even make it through a week of camp. The undrafted free agent out of Florida never pushed Tyrod Taylor or Curtis Painter for backup duties behind Joe Flacco.
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F/W 2013-2014: The leather trend
If the crystal ball used by fashion designers holds true, we can look forward to women decked out as urban warriors next winter. So far this week, catwalks have been filled with models encased in thick coats, layers of fur, and leather. It almost feels like a prerequisite for designers to include at least one black leather piece in their collections for Fall/Winter 2013.
"I think there is still this general anxiety," said Joanna Coles, editor-in-chief of Cosmopolitan magazine. "We live in anxious times. Remember, designers were creating these collections before the election, and there was a general fear in the creative field that the Republicans might win. Sandy was also very much on people's minds when these collections were born. All of that uncertainty was there, and now you can see it."
Hayley Kaufman is editor of the Style section.
Rachel Raczka (@rachelraczka) is the lifestyle producer for Boston.com.


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Slacker Uprising
Michael Moores Slacker Uprising Free download. Michael Moore's SLACKER UPRISING
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we went to the store and we spent 11.00 for milk and bread .
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LITTLE ROCK (AP) - The Arkansas Department of Human Services says 25 hospitals have received $4.1 million in bonus payments for improving the quality of care that patients receive.
Arkansas Medicaid handed out the awards to hospitals as part of its pay-for-performance Inpatient Quality Incentive program. The program tracks hospitals' performance in several categories, including the number of elective births for women before 39 weeks of pregnancy.
Arkansas' Medicaid Medical Director Dr. William Golden says that babies born before 39 weeks are at greater risk of complications.
The agency says that in 2009, 33.6% of all births in Arkansas happened in weeks 37 and 38. In 2011, that number dropped to 27%.
Baptist Health Medical Center, Washington Regional Medical Center and Sparks Regional Medical Center are among the hospitals that received awards.
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The Providence Journal / John Freidah
With temperatures reaching the 90s even at the coast, people flock to Narragansett Town Beach looking for relief.
PROVIDENCE, R.I. -- It was hot, but not that hot.
Temperatures Thursday afternoon appeared to level off at 93 degrees, short of warnings that it could hit 100 degrees today.
The record high for this day, set in 1941, remains intact at 96 degrees.
The National Weather Service issued a heat advisory Thursday morning, saying heat indices of up to 103 degrees will present "dangerous conditions for those spending prolonged periods of time outside."
Friday looks only slightly cooler, with a high of about 93 degrees inland and low to mid 80s on the shore. Thunderstorms are possible.
The weekend brings relief. Saturday's high should reach just 83 degrees. Sunday's should hit 80.
For more weather and updates, see providencejournal.com/weather.


text:
Robert Crossley. Imagining Mars: A Literary History. Middletown, CT: Wesleyan Univ. Press, 2010. 6 x 9 ", 384 pp. $40.00 cloth ISBN 978-0-8195-6927-1
"A substantial and delightful book on the literary images and narratives of Mars; eminently readable, full of imaginative insights that will in turn awaken the reader's own imagination to the wonders of the universe." --Steven J. Dick, former NASA chief historian and author of The Biological Universe "I know of no other book that attempts such a vast survey, holding together the literatures of science fiction and of the scientific study of Mars. Crossley's focus allows him to analyze the relation of science fiction to the modern history of scientific understanding with a precision, authority, and textual detail that a more traditional history of the genre could never attain." --John Huntington, professor of English, University of Illinois at Chicago
"This is a remarkable study, showing how attitudes and conceptions of Mars have evolved in the popular imagination. The scholarship is solid and thorough, presented in a fascinating and easy-to-read fashion."--Peter Fitting, editor of Subterranean Worlds