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While top fixed rate deals might be thin on the ground at the moment, there are alternatives to traditional fixed rate bonds, such as structured deposit plans, which could be Read More
As we approach the start of a new year, savers may be considering a new home for their money in order to make the most of their hard-earned cash in Read More
Although the drop in the headline rate of inflation by 0.5% is good news for savers, the interaction between inflation and interest rates when considering the outlook for savings rates Read More
Here we highlight a selection of some of the current fixed rate bond deals for April 2013 – as well as some alternative ideas if you're happy to tie up capital for 3 years or more. 1. Sh... Read more
With interest rates at record lows, locking cash away in a fixed-rate bond is no longer a guarantee of getting a good return. With the Government's Funding for Lending Scheme giving banks chea... Read more
At a time when good fixed rate ISA deals are hard to find, NatWest have launched competitive one and two year fixed rate cash ISAs. These plans allow savers the option of one or two year fixed tem, ... Read more
ING Direct fixed rate bonds allow you to earn high returns on your money, All you have to do is lock your money away for a fixed period of time. Before you make any decisions about ING Direct fixed rate bonds, use our comparison table below to compare some of the top UK fixed term deposit accounts and apply online for an ING Direct Savings Account:
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The Flavor Thesaurus: A Compendium of Pairings, Recipes and Ideas for the Creative Cook (Hardback)
$25.65 - Save $1.35 5% off - RRP $27.00 Free delivery worldwide (to United States and
all these other countries) Usually dispatched within 48 hours | |Short Description for The Flavor Thesaurus A complete guide to the 160 most essential flavors and their numerous combinations, this lively and exceptionally enjoyable book uncovers the essential flavors of food and organizes them into 160 basic ingredients.
Full description- Publisher: Bloomsbury Publishing PLC
- Published: 24 April 2012
- Format: Hardback 400 pages
- See: Full bibliographic data
- Categories: Reference Works | Food & Drink | General Cookery
- Sales rank: 6,309
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Full description for The Flavor Thesaurus
Niki Segnit's essential culinary reference book is now available with an award-winning, internationally acclaimed design. As appealing to the novice cook as to the experienced professional, it will immeasurably improve your cooking--and it's the sort of book that might keep you up at night reading. Beautiful, entertaining, and exhaustively researched, this is a globetrotting collection of flavor pairings as told by a writer with a discerning palette and an entertaining, original voice.


text: This product belongs to: Credit Card Holders Category: Pocket & Purse Subcategory: Business Card Holders Ships In: 2 - 3 business days (pending credit, art, and proof approval) Material: Leather Imprint Area: 2.0 in. W X 0.5 in. H Decoration Method: Debossing, HotFoilOtherColor Weight: 12.5lb. This stylish no-nonsense credit card and mini ID holder shows recipients that you take your business seriously. Made from top-grain nappa leather, the moire-lined item features three credit card pockets and an ID window. Were you able to find what you were searching for? Zero Risk ShoppingLowest Price GuaranteeIf you find a lower price, we'll give you 36 mugs FREE with your order. 100% Satisfaction Guarantee If you're not happy with your order, it's FREE. On-time Shipment Guarantee If your order does not ship on time, it's FREE. Frequently Asked Questions about this ProductQ: How do I upload artwork? A: To use a graphic located on your local computer, click on the "Upload Now" button on the "Step 1: Get Your Artwork" page of the design studio. This will lead you to a new page. Click the "Browse" button and look for the file on your computer. Q: What is your Lowest Price Guarantee and how does it work? A: We guarantee that the item you are purchasing has the lowest price in the US. Be the first to find and report to email@example.com an advertised price that is lower than what you find on our site for the same product in a given Q: Why do minimum quantities differ from product to product? A: Minimum quantity requirements vary from manufacturer to manufacturer. In cases where a manufacturer's minimum order requirement exceeds your requested quantity, a Branders.com Specialist will assist you. Call us at 1-877-272-6337. Write in your question about this product: AVAILABLE COLORSCUSTOMER REVIEWS2 reviews All the products that I have ordered were good except the Christmas ornaments which were refunded back to me. The very good price of this, along with the sturdy feel sold me to it. It was quite helpful that I was able to get myself a sample of this before ordering in bulk. PEOPLE WHO VIEWED THIS ALSO VIEWEDMORE UPSCALELOWER PRICELOWER MINIMUMSFASTER TURN AROUND |


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Nanoelectronic Modeling Lecture 41: Full-Band and Atomistic Simulation of Realistic 40nm InAs HEMT
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05 Aug 2010 | Online Presentations | Contributor(s): Gerhard Klimeck, Neerav Kharche, Neophytos Neophytou, Mathieu Luisier
This presentation demonstrates the OMEN capabilities to perform a multi-scale simulation of advanced InAs-based high mobility transistors. Learning Objectives: Quantum Transport Simulator …
nanoHUB.org, a resource for nanoscience and nanotechnology, is supported by the National Science Foundation and other funding agencies. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.


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Everything Nurses >> Nurse Talk >> HIV Update
HIV Update
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Posted 12 months ago HIV Facts: Injection drug use (IDU) accounted for 12% of estimated new HIV infections in the United States in 2010. Philadelphia reported a slightly higher statistic of 13%. Each year, more than 45,000 people become newly infected with HIV in the United States The CDC recommends that everyone in the US aged 13-64, regardless of perceived risk, get tested for HIV to help stop the spread of the disease.
2010 CDC data indicates about half of the just over 1 million Americans living with HIVS or AIDS are black. In 2010 the rate of new HIV infections among non-Hispanic blacks was 7 times the rate among whites. Hispanics saw a rate 3 times that of the white population. Whites accounted for 35% of estimated new HIV infections. Asians/Pacific Islanders accounted for roughly 2% and American Indians/Alaska Natives accounted for roughly 1%.
Philadelphia statistics however reported heterosexual's accounted for the largest population. Every 9 1/2 minutes another person becomes infected with the HIV virus in the United States. The CDC estimates that African Americans are more severely and disproportionately affected by HIV than any other racial/ethnic group in the United States.
Each year, more than 45,000 people become newly infected with HIV in the United States. In the United States, men account for 73% of new infections. Philadelphia reports African American women are the fastest growing population.


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Montebello di Bertona Vacation Rentals, Villas, & More
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Vacation farm in the hills of Central Italy
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- 6
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from$49/ night
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- Local Guides/Maps
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Campo di Forni is an olive producing organic farm adjacent to the Gran Sasso Laga National Park in the Abruzzi Region of Central Italy. It offers accomodation in a renovated and ecologically friendly farm building. Meals are provided, for residents guests only, and are based on the organic products of the farm. Guests can…
- Pet friendly
- Smoking allowed
- Suitable for children
- Suitable for the elderly
- Wheelchair accessible
4 guest reviews
100% of guests would stay again
Great Place near the Gran Sasso
Left on Oct 06, 2012 for a stay in October 2012
This is a B& B. It was initially 2 farm houses which Nadia converted and replaced with one very stylish and modern building two yrs ago. It has all the amenities including modern bathrooms, a place where meals can be served along with a television room.
Nadia has a wealth of information about the surrounding area. Our favorite trip was up the Gran Sasso mountain range and then onto the plateau … See more
BobR3, Stuart
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Documentaries & Doughnuts
When: Feb. 6, 2013, 9am - 12pmShow Recurring Dates
Campus Location: Houssels House
Office/Remote Location: Center for Social Justice Library
The Center for Social Justice invite you to stop by for free coffee and doughnuts while casually enjoying a documentary. You can stop by for a few minutes in between classes or stay and hang out for the entire film.
Films will be playing from 9 a.m. to noon.
Admission Information:
Free and open to all UNLV students, faculty and staff.
Contact Information:
Name: Brandon Hildreth
Office: Office of Civic Engagment & Diversity, Center for Social Justice
Phone: 702-895-4053
E-mail: firstname.lastname@example.com
Related Events
- 2014 Rebel Awards
Starts Mar. 09, 2014, 12pm
Ends Mar. 09, 2014, 5pm - Ukrainian Crisis Forum
Starts Mar. 10, 2014, 3pm
Ends Mar. 10, 2014, 4:30pm - "Art for Art's Sake" Art Exhib…
Starts Mar. 10, 2014, 9am
Ends Mar. 10, 2014, 5pm - Movies that Matter: "The Insti…
Starts Mar. 10, 2014, 7pm
Ends Mar. 10, 2014, 9:30pm


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The historic three-story brick building - a former church gym built in 1925 - has stood vacant and for sale on the north end of Fort Worth's Fairmount neighborhood for about as long as anyone remembers.
Fort Worth is getting an addition to its roster of small brewing companies: Wahoo Brewery, a startup.
FORT WORTH - Ramon Romero Jr. describes himself as "that poor boy from Poly," one of eight children of immigrant parents who grew up in working-class southeast Fort Worth, started his first business when he was 20 and ultimately became an up-by-the-bootstraps success story.
When Tonya Veasey founded her Fort Worth-based public relations agency in July 2005, she intended to take on just a client or two. Today, her list of clients is in the hundreds and it
Texas Capital Bank has leased 19,000 square feet at One City Place and will move from its current location at The Tower to become the first tenant to occupy the 300 Throckmorton St. building, according to Holt Lunsford Commercial Inc.
CHICAGO (AP) — The agency that oversees public transportation in Chicago is suing Fort Worth-based American Airlines for falsely claiming to buy "vast amounts of jet fuel" from a small office in a rural community to avoid paying tens of millions of dollars in taxes in the nation's third-largest city, where the actual work is done.
HOUSTON (AP) — Fewer than 90,000 Texans bought health insurance through the new federally subsidized marketplace in the past month, leaving navigators, assisters and other officials working to enroll people with a hefty task as they near the March 31 deadline for open enrollment.
AUSTIN, Texas (AP) — January's polar vortex knocked several important coal-fired electricity plants in Texas offline, and the Sierra Club on Tuesday said the loss of power shows the state needs more wind turbines and energy conservation programs to avoid possible rolling blackouts.
AUSTIN, Texas (AP) – The candidates for Texas governor sparred over two separate issues Tuesday, with Democratic state Sen. Wendy Davis insisting her opponent won't commit to solidifying gender pay equality into state law and Republican Attorney General Greg Abbott firing back that Davis' law firm may have profited from her work in the Legislature.
NEW YORK (AP) – Looks like the best suitor won.


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Friends for Youth's Senior Friends volunteer to spend time with a Junior Friend between the ages of 8 and 17, solidifying a relationship of trust and support with weekly activities such as going to the movies, visiting the zoo, and reading together. Friends for Youth plans to send mentor and mentee pairs on an adventure trip to Lake Tahoe to help strengthen the bond between Friends and introduce youth to exciting outdoor activities such as skiing and snowboarding. With $300, a mentor-and-mentee pair can attend the trip, with funding to cover the cost of transportation, a meal, skiing or snowboarding lessons, and equipment rental.
SportZal's corrective fitness experts prime physiques for a slip-free season of soaring down slopes with their snow-sports preseason conditioning boot camp, which has readied skiing staff members at both Squaw Valley and Alpine Meadows snow-sports schools. A body assessment and consultation first generates a custom program around athletes' goals. Up to eight students then augment mountaineering muscles with strength training, and flexibility drills teach arms to simultaneously steer and knit a sweater with ski poles. Training stages follow precedents set by the US Ski Team, boosting base strength before asking students to work at maximum power, and then easing into agility exercises. Limbs also unfurl into healing yoga poses to avoid such snowboarding strains as aching knees and back pain prompted by hugging yetis.
Though Core Studio's workouts blend elements of Pilates, resistance-training, and strength-training, the company's entire program has three core methods: SPX fitness, Core Barre, and RealRyder indoor cycling. Each of the studio's instructors are masters of both. The Core SPX workout has a specific science designed to work muscles toward their limits and the heart toward victory. Armed with this knowledge, the instructors motivate clients to sweat through flexibility and core-strength-enhancing workouts in four classes: Core SPX, Core Barre, Core Cycle, and Core 30/30, a blend of SPX and Cycle. SPX workouts use the Megaformer, a state-of-the-art Pilates reformer that relies on spring resistance, whereas Cycle classes use the RealRyder indoor cycle—a stationary bike that isn't actually stationary. As it turns and tilts with riders, mimicking the motions of a real bike ride, the machine encourages functional movements, such as pedaling faster to escape a pack of invisible wolves.
At Menlo Hub, both food and art find a place on the menu. The modern restaurant's walls are blanketed in original contemporary paintings, and on some nights, the dining space reverberates with music from live bands and solo musicians. But even on nights with performances, the main attraction is always found in the kitchen. Here, chefs design casual American dishes sprinkled with elements of Mediterranean cooking.
The menus focus on simple steaks and seafood, complemented by organic produce sourced from nearby sustainable farms. The artfully plated dishes include California sea bass, New York steaks with gorgonzola demi-glace, and eggplant-wrapped lamb shanks. While most visitors sample the cuisine in the airy main dining space, private groups eat in a secluded room warmed by a corner fireplace.
At the lively bar, flat-screen TVs broadcast sporting events as bartenders mix fruit-infused martinis and pour a range of California wines, which are made from grapes that are just thankful that they never became California raisins.
The Burlingame Museum of PEZ Memorabilia celebrates iconic candy packaging with its exhibit of PEZ dispensers, featuring the plastic disembodied heads of animals, cartoon characters, comic-book heroes, and more. With two tickets ($3 each), you and a friend can peruse recent additions to the exhibit, including wistfully philosophical Peanuts PEZ dispensers from 2000 and a Mary Poppins dispenser from the 1960s that has been appraised as practically perfect in every way. Other confection-spouting dispensers feature likenesses of Mickey Mouse, Batman, Santa Claus, and beloved comic-book super-heroine Betsy Ross. In addition to pint-sized PEZ packaging, the museum also houses the world's largest PEZ-dispensing machine, standing nearly eight feet tall, weighing 85 pounds, and capable of storing numerous PEZ candies or UFO-related secrets.


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Irving >
Food & Dining > Kasbah Cafe-Mediteranean GrocMon. CLOSED;Tue. - Thu., Sun. 11am - 9pm;Fri. - Sat. 11am - 9:30pm
Editorial Review by Citysearch Editors – Casual Moroccan spot in Irving emphasis on quality traditional dishes for lunch and dinner.
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Together, Whirlpool and Maytag emerge a more compelling company positioned to deliver the most innovative portfolio of products and services to consumers throughout the world. Together, they will continue to find new ways to delight consumers while striving to fulfill their vision of "Every Home . . . Everywhere with Pride, Passion and Performance." Now more than ever, they believe that their bold innovation and designs will connect with consumers in meaningful ways that will last a lifetime. Available at Goedeker's.
This under-cabinet vent hood offers a sleek, modern design for your kitchen. It features a 2-speed fan that effectively circulates kitchen air and dishwasher-safe filters that help minimize cooking odors. The under-cabinet exhaust system is classical and functional and Includes a 190 CFM updraft ventilation system.Features:
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September 17, 2003
Moultrie - More than a dozen stores and restaurants are busted for selling alcohol to underage people.
Eleven convenience stores and two restaurants in Moultrie were found selling beer to underage customers during an undercover sting.
On Friday, workers at each business did not card an 18-year-old and an undercover Moultrie Police officer. The individuals who sold the alcohol will be charged.
posted at 6:25PM by email@example.com


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East Burnside
A Portland neighborhood blog by Melissa Ooms
Date Range: April 30, 2009 - April 1, 2009
Annual 'Kerns Neighborhood Clean-Up'
Melissa Ooms
April 16, 2009, 1:15PM
Mark Your Calendars -- this weekend is the annual Kerns Neighborhood Clean-Up! Join your neighbors to help pick up litter and assist in beautifying the area. Participants should meet at 2625 E Burnside (in the parking lot of the Jones Kendall Sauer Inc. insurance company) at 9:00 a.m. The project lasts until about noon.
Full story »
Thursday, April 16, 2009, 1:39 PM
Copyright 2012 OregonLive.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
Your blogger is BACK
Melissa Ooms
April 06, 2009, 10:04PM
The Good News: Starting today, I will be reporting on one of the best neighborhoods in town, the East Burnside/Kerns/Laurelhurst areas, on a much more regular basis. The Bad News: It's because I have lots more time now that I have been laid off from my job.
Full story »
Tuesday, April 07, 2009, 8:21 AM
Copyright 2012 OregonLive.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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Developing a successful palliative care service in an acute care setting.
Ross K, Mathis S, Brockopp D. J Nurs Adm. 2008 Jun;38(6):282-6.
Hospitalized patients with chronic illness require the same aggressive symptom management as those of hospice patients. Unfortunately, many individuals with chronic conditions require aggressive symptom management but they are not candidates for hospice admission. The authors discuss a palliative care service developed in a 371-bed community hospital to address this need. This consult service has improved patient care without draining hospital resources.
End-of-life care and social work education: what do students need to know?. Huff MB, Weisenfluh S, Murphy M, Black PJ. J Gerontol Soc Work. 2006;48(1-2):219-31. Social workers are major service providers to people who are facing end-of-life issues including the terminally ill and their families. Yet, exemplary models for social work education and intervention methods are limited in rural states. A statewide survey conducted in Kentucky found only two social work courses dedicated to end-of-life care currently being offered by accredited undergraduate and graduate institutions. Another statewide survey found that many hospice social workers are relatively inexperienced and have a need and desire for more education on death, dying and loss. Also, unique cultural, economic and geographic areas, such as Appalachia are enigmas when it comes to the provision of end-of-life care. This partnership provides a varied perspective on delivery of end-of-life care services with an emphasis on social work interventions and education
Is there a model for demonstrating a beneficial financial impact of initiating a palliative care program by an existing hospice program? Passik SD, Ruggles C, Brown G, Snapp J, Swinford S, Gutgsell T, Kirsh KL. Palliat Support Care. 2004Dec;2(4):419-23 The value of integrating palliative with curative modes of care earlier in the course of disease for people with life threatening illnesses is well recognized. Whereas the now outdated model of waiting for people to be actively dying before initiating palliative care has been clearly discredited on clinical grounds, how a better integration of modes of care can be achieved, financed and sustained is an ongoing challenge for the health care system in general as well as for specific institutions. When the initiative comes from a hospital or academic medical center, which may, for example, begin a palliative care consultation service, financial benefits have been well documented. These palliative care services survive mainly by tracking cost savings that can be realized in a number of ways around a medical center. We tried to pilot 3 simple models of potential cost savings afforded to hospice by initiating a palliative care program. We found that simple models cannot capture this benefit (if it in fact exists). By adding palliative care, hospice, while no doubt improving and streamlining care, is also taking on more complex patients (higher drug costs, shorter length of stay, more outpatient, emergency room and physician visits). Indeed, the hospice was absorbing the losses associated with having the palliative care program. We suggest that an avenue for future exploration is whether partnering between hospitals and hospice programs can defray some of the costs incurred by the palliative care program (that might otherwise be passed on to hospice) in anticipation of cost savings. We end with a series of questions: Are there financial benefits? Can they be modeled and quantified? Is this a dilemma for hospice programs wanting to improve the quality of care but who are not able on their own to finance it?
A pilot study of the impact of a grief camp for children. Nabors L, Ohms M, Buchanan N, Kirsh KL, Nash T, Passik SD, Johnson JL, Snapp J, Brown G. Am J Hosp Palliat Care. 2002 Mar-Apr;19(2):129-34. OBJECTIVE: Research indicates that children benefit from supportive interventions to help them cope with the loss of a loved one. The aim of this pilot study was to evaluate children's perceptions of the effectiveness of a grief camp. METHODS: Semistructured interviews were performed with 18 children who attended a weekend-long grief camp. Children also responded to follow-up interviews via telephone. Their parents also completed surveys before camp began and either after camp ended or at a follow-up evaluation. Data were analyzed using descriptive statistics and content coding to uncover key themes in the interviews. RESULTS: Children reported that art activities helped them to express feelings about their grief and release feelings of sadness and worry related to the death. Parents and children felt that the camp was a positive experience and that the children benefited from being in groups with peers who had also lost family members. SIGNIFICANCE OF RESULTS: Evaluating the impact of grief camps, using practical methods such as the ones for this study, is important, as these camps are becoming more popular interventions. Children and parents may benefit from contact at specified follow-up periods after camp to determine if they would benefit from further therapy. Results also provide evidence of the success of this program, which supports the need for funding these types of interventions.
Hospice staff members' views on conducting end-of-life research. Kirsh KL, Walker R, Snider S, Weisenfluh S, Brown GM, Passik SD. Palliat Support Care. 2004 Sep;2(3):273-82. OBJECTIVE: Hospice staff members have concerns about the appropriateness of enrolling terminally ill people in research studies. These concerns can have profound implications for the advancement of palliative and hospice care as they can impede the empirical investigation of interventions for improving the quality of life of patients with advanced disease. This survey study was designed to examine hospice staff attitudes, beliefs, and values about research with their patients and family members. METHODS: This study utilized a cross-sectional, anonymous survey design to measure hospice staff members' beliefs, attitudes, and values. The survey contained questions derived by hospice and palliative care experts from their experience and review of the literature. It was handed out at staff meetings and returned via mail. The survey contained 14 questions and was able to be completed in less than 5 min. RESULTS: A total of 225 participants (56.25% response rate) completed the survey and were included in the data analysis. Hospice staff members were largely supportive about the idea of conducting research with patients and family members (mean agreement of 4.08-4.44 on several perception items about research on a 1-5 scale). They also acknowledged a mixture of being protective of controlling access to patients (52% wanted to be the ones to approach patients) and not having enough time for research (59% either had no time or would be willing to spend no more than 10 min on research). SIGNIFICANCE OF RESULTS: Although many of the opinions derived from the survey appear to indicate a willingness to embrace research in a hospice setting, significant barriers, especially time constraints and protective attitudes, remain. Educational efforts and firsthand involvement in the research process might be a useful first step in attempting to address these barriers and traditionally held beliefs against using hospice patients and families in research.
A prospective study of the pathophysiology and clinical characteristics of pain in a palliative medicine population. Gutgsell T, Walsh D, Zhukovsky DS, Gonzales F, Lagman R. Am J Hosp Palliat Care. 2003 Mar-Apr;20(2):140-8. Comprehensive pain evaluation is requisite for optimal management. Few studies have evaluated pain syndromes and adequacy of associated analgesic regimens in one population. Available studies in cancer populations have focused on ambulatory patients or hospice-type inpatients. This study was designed to evaluate multiple characteristics of pain and adequacy of therapy in a broad spectrum of patients with advanced cancer presenting to a palliative medicine service. One hundred pain patients (95 with cancer) underwent a comprehensive pain evaluation consisting of history, physical examination, review of available diagnostics, and a pain assessment tool designed for routine clinical use. Seventy-one percent of 141 evaluable patients reported pain in the month before referral. In these 100 patients, 158 distinct sites of pain were reported, with 88 percent reporting a maximum of 2. Pain due to tumor was the most common cause (68 percent), and the most common pathophysiologic mechanism, somatic (52 percent). Pain was almost equally divided between continuous (48 percent) and intermittent (52 percent). Breakthrough pain occurred in 75 percent of continuous pains. Of these, 30 percent were exclusively incidental, 26percent nonincidental, and 16 percent due to end-of-dose failure. The remainder was of mixed etiology, but almost always with an incidental component. Of intermittent pain syndromes, 61 percent were incidental. On referral, analgesic dosing was inadequate and was compounded by use of regimens that typically did not meet peer-reviewed guidelines. Comprehensive studies rigorously evaluating characteristics of pain and response to treatment are a necessary first step toward more effective treatments for difficult pain syndromes.


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According to state officials, Tierney pointed to flu season, anxiety and lack of hand washing as reasons for the hospital visits in a Jan. 18 conference call.
"We're in the middle of flu season and virus season. Many of us haven't been able to consistently wash our hands with soap and water. While the sanitizer is good for cleaning, it isn't great for eliminating a virus. Some people are getting these viruses, as many do every winter." Tierney said, according to a news release.
While he mentioned nobody by name, Gupta seemed to directly contradict that statement.
"We obviously cannot explain away [symptoms] by saying it's the flu or something else. At this time, we shouldn't even try to," Gupta said.
He emphasized that symptoms people were seeing -- rashes, eye irritation, nausea, vomiting, diarrhea, stomach aches -- were not necessarily caused by the chemical. But he also said that it was very likely that the number of affected people could be too low, not too high -- that many people decided to "tough it out" and never even went to the hospital.
Asked why he showed so much less certainty than Tierney, Gupta said, "Maybe the fact that this is not my first rodeo. I've been through these things and I've done this for a long time."
Tierney has been commissioner of the Bureau for Public Health since Nov. 1. Previously she had been a physician and associate quality director at Charleston Area Medical Center since 2010.
"We maybe have different philosophies," Tierney said after the hearing of her divergence with Gupta. "I feel that in public health we've got to be careful how we craft our statements to provide confidence to the public, especially when we're going on evidence-based medicine."
Asked if she felt she was providing confidence to the public, Tierney said, "I know I'm being honest, I know I'm being truthful and I know I'm being as transparent as I can, and if that doesn't give confidence, I'm kind of at a loss where else to go."
Tierney emphasized that the state has been consulting with a broad range of federal agencies -- ATSDR, CDC, the Environmental Protection Agency, the National Institutes of Health -- but declined to name any individual scientists, saying there were probably 50 to 60 of them.
"These experts are not always recognized by name, but by the agencies they serve," she said.
She also said there were "some confidentiality agreements involved."
Senate Majority Leader John Unger, D-Berkeley, asked Tierney for both the names of the scientists the state has consulted with and the detailed methodology behind the water tests that the state has conducted. Unger said that when federal agencies release reports, they usually come with names at the top.
"They put their names on their reports. This veil of secrecy is very unusual," Unger said after the hearing. "That's where the trust factor is falling down."
Reach David Gutman at david.gut...@wvgazette.com or 304-348-5119.


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Fluval Chi 5G - My first tank
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Otos are constant foragers and their bellies should be nice and fat at all times :P Some otos will eat wafers while others will just ignore them. I think you'll need to experiment and figure out what your oto likes but it wouldn't hurt to grab some. Your fish will eat them as well!
Originally Posted by
The water parameters that my kit tested for were safe, and 6 days had passed so I just followed what I read others online had done. I was also a little eager to at least get the oto as the algae was spreading. The Nutrafin came with the tank, and even questioning the product, I assumed that the plants would have definitely introduced some bacteria? I'm quite new to this so I would appreciate if you could elaborate what I should have done?
I read several times online that otos don't actually eat algae wafers but that seemed to be quite a debate. I've added some lightly blanched lettuce in with a plant weight, other than that I'm torn what to do based on the opposing opinions I've read. It seemed people on both sides had success.
Other than the oto and shrimp, would it be a good idea to eventually get other small fish? Tetra wouldn't work because I've read I need a minimum of 6, and my tank is too small for 6. I was reading that white clouds could be a compatible addition, anything else?
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Just bought a new Bersa 380 with a 15/clip, but could only load 12 bullets, simply too hard after that, does it take time to break in a magazine spring or could there be something wrong?
Just bought a new Bersa 380 with a 15/clip, but could only load 12 bullets, simply too hard after that, does it take time to break in a magazine spring or could there be something wrong?
I don't have the Bersa .380 Plus, but I've read other reports of mgs being hard to load. One thing that is recommended is dissassembly of the mag, clean it real good & check for burrs/obstructions inside the tube with a Qtip. If nothing is found there, could be the spring just needs to "take a set". With use, it should get easier & easier to load. Some just load it up as tight as possible & let it sit for a week or two. A Uplula Jr. loader may be helpful also.
P.S. You might enjoy the sister forum, Bersa Chat. A lot of Bersa owners with lotsa advice. We try to have a little fun also.
Last edited by mitchr; 02-21-2012 at 03:54 PM.
I had the same thing with all three of my 15 rounders trying to load them by hand but since I already had an UPLULA I used that and had no problems, not entirely sure if the UPLULA jr. will work on the double stack mags for the Plus but I know for certain my regular one does the job
You need the loaded my 9mm UC was a bear to load the 10 thru 13 round get a loader and lets the mags sit loaded It won't hurt them .
http://condorsflight.com has the loaders. good fast service.
"Hokey religions and plastic glocks are no match for a good BERSA at your side, kid."
bersachat.com Where Bersa & American Classic owners call home
It happens in both smaller and larger magazines. That spring inside the magazine gets really tight towards the end of its travel.
Use a loading assistance device to fully load the magazines, otherwise just load what you can by bare hand.
In my standard 7 round magazines I routinely load only 5 rounds if I don't have some kind of assist device, for example the last time I was at the range and forgot to bring the loader.
It's kind of a compromise situation. They could have a wimpy spring in there and have more "Failure to feed" problems when the magazine is mostly empty, or they can have a strong spring that makes it hard to load those last few rounds but keep the gun more reliable.


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Student Fees
Please be aware that as exchange students you are responsible to pay for certain fees during your exchange term at Wilfrid Laurier. Please read this information carefully and budget accordingly. These are not tuition fees.
Be sure to review the insurance plans that you will be enrolled in before purchasing insurance from your home country.
Non Academic Student Fees
All students will be charged certain student fees based on the subject of study and the amount of courses that you enroll in. For budgeting purchases, you should plan to pay approximately $460 per term for these fees.
The student services fee will give you access to our state of the art Athletic Centre, Student Union & Centre, a range of other student services, and a city bus pass that you can use unlimited during your term at Wilfrid Laurier. More information about the student services that are included in your fees can be found here: http://www.wlu.ca/page.php?grp_id=151&p=11760
Information about student fees for undergraduate students can be found here: http://www.wlusu.com/student-fees/
You may be able to OPT out (not pay) some fees if you complete the necessary steps BEFORE the deadline. Be sure to check back on this site http://www.wlu.ca/page.php?grp_id=1272&p=5029 for more information. It is currently out of date, but will be updated before you arrive.
TIP: Understand what you are paying for and use these resources!
Universal Health Insurance Plan (UHIP)
UHIP is compulsory because you are not covered by the government health plan in Ontario. The charge will be approximately $250 per term. More information about UHIP can be found at the following links:
Health & Dental Plans
Student extended plans provide additional coverage for services that are not covered under UHIP. These extended plans ARE COMPLETELY SEPARATE HEALTH INSURANCE PLANS FROM UHIP. We recommend that you review these plans and take advantage of the benefits during your time in Canada.
All Undergraduate Students will be enrolled in the Undergraduate Health and Dental Plan. More information about this plan can be found here: http://www.wlusu.com/services-section/health-dental/
The Plan Fees for 2013-14 will be 107.66 for Health and 101.05 for Dental for a total of 208.71. You have the option of opting out of these plans ONLY IF YOU HAVE EQUAL COVERAGE. You can contact this email if you have any questions: email@example.com
All Graduate Students will be enrolled in the Graduate Health & Dental Plan. More information about this plan can be found here: http://www.wlugsa.ca/index.php/programs/health-and-dental-plan
The Plan Fees for 2013-14 are $348.33 for Health and $172.23 for Dental. You have the option of opting out of these plans ONLY IF YOU HAVE EQUAL COVERAGE. You can contact this email if you have any questions: firstname.lastname@example.com . For students coming in the Fall term only, you will be able to be partially refunded for the Winter term provided you complete the form by the required deadline. More information can be found at www.wlugsa.ca


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Please Don't Quote Me This Week
It could have been Cortez or DeSoto; perhaps, Magellan or Cook. Maybe Columbus. But instead of any of those early day explorers, Zenas Aplington's choice to name the town was Polo, for Marco Polo.
Click on the Flag for More Information
"Gentle Dave," an on line reader, commented on the PA newspaper and web site - www.pacc-news.com - August 2, 2012:
I'm an old newspaper journalist who currently writes for a local community newspaper in one of Chicago's neighborhoods. I'd like to compliment and congratulate your newspaper, I truly enjoy reading it.
In these days and times a newspaper like yours is vital in order to inform the public of what really goes on in this world, even if locally. Too much of the public believes exactly what is written in most newspapers, and as you know, most newspapers have their own agenda and don't always report the truth.
I particularly enjoyed reading of the new Illinois state laws that took effect January 1, 2012. I have not seen any Chicago or metropolitan newspapers publish such a list which is so vital to the public.
Congratulations and keep up the good work, you have a new reader and supporter!
I get it now.
Maybe the rest of the nation is also tired of politics as usual, Illinois style.
Rep. Frank Wolf (R-Virginia) continues to block the sale of Thomson and now several other Senators and Representatives from other states have joined him with additional reasons for not funding Thomson. Wolf thinks Obama is pulling the wool over our eyes and still will bring GITMO prisoners to Illinois. The other Senators and Representatives sight the (4) new federal prisons already built, but not opened. They are located in Yazoo City, Miss., Berlin, N.H., Aliceville, Al., and Hazelton, W. Va.
The Associated Press, in a study trying to determine the cost of private prison companies over a 10 year period, found three private companies, Corrections Corporation of America (CCA), The GEO Group, and Management and Training Corporation. CCA was on the verge of bankruptcy in 2000 according to the AP study. Loss of contracts, management problems, and lawsuits were sighted. In 2011 CCA earned $162 million in net income with 43% of that income coming from the Federal Government. GEO net income rose from $16.9 million to $78.6 million.
These three companies have spent at least $45 million on campaign donations and lobbyists at both state and federal levels. (My lightbulb just came on!)
Here's my thoughts using a little common sense. (We all know how far that seems to go in politics).
Opening Thomson as an Illinois Department of Corrections facility:
1) Could create 600 real jobs with real pay checks spent in the local economy.
2) Illinois could house Federal prisoners and State prisoners, relieving over-crowding.
3) Create jobs for returning vets.
4) Save the Federal Government $165 million.
5) Actually show bi-partisan cooperation.
Jo-Carroll Energy could offer an incentive on electric and gas rates if Illinois would pay the bill on time. Failure to pay on time sends them back to regular rate. I think the design of Thomson compared to most Illinois prisons will show the lowest energy usage in the state. That could become even more efficient if an Iowa Wind Generator were installed.
Did you know the Federal Government requires a bachelor's degree in criminal justice, not over 37 years old, and mandatory retirement at 57? Illinois requires a high school diploma. Federal has over 20,000 applications on file.
How can we lobby so the little guy (like Thomson, IL) can grow?
Kirk Wellman Erie, IL
(Publisher's Note: At a July 19 rally in Springfield, prison employees described a spike in inmates punching, spitting on and biting guards, saying the incidents worsened in recent years because of overcrowding. And a July 24 report documented what a union representative described as "a riot," fueled by understaffing and overcrowding, at a minimum-security prison in East Moline during a power outage. And the State says we are not overcrowded.)
I'm happy for Mr. Greg Wahl, CEO of Wahl Clipper Corp., that his "threatened species" will be protected. I just wish that the zoning panel cared as much for the human beings that they are condemning to a miserable existence on their own land, if indeed, they will be able to continue living there.
Nobody on these panels seems to have a conscience about what they are doing to their neighbors. Mr. Mike Crowley surely doesn't have one–$12,000 has bought and paid for his "opinion" that property values won't be affected when the wind turbines come in. I bet he sleeps just fine.
It's sad we "little people" don't have taxpayer subsidies to buy someone to tell the truth of the matter—not that the panels would listen or care anyway.
Appraisal consultant Mike McCann, of Chicago, IL, whose resume includes zoning evaluations, value impact studies, analysis of wind turbine generating facilities, and evaluation of eminent domain real estate acquisitions, advises residents bluntly, that no permits should be issued on any wind generation project without a property value guarantee for homeowners in the turbine area of influence.
He said the impact zone of a wind farm is two-to-five miles with value loss up to 40% depending on distance away from turbines. Not to mention the losses of those forced to walk away from their homes. "The mass erection of wind turbines near people's homes is a form of taking from the property owner and giving to the wind developers," he added.
Why isn't wind-turbine noise getting more attention from the EPA? They have plenty of resources to plague the natural gas and oil sectors. Meanwhile, the wind industry is getting a free pass.
Sleep well, those of you we have voted for and trusted to protect our way of life.
Sue McGinn Tampico, IL
(Publisher's Note: See more details from the Chicago Tribune article at this link: http://articles.chicagotribune.com/2012-06-19/news/ct-met-turbine-endangered-species-20120619_1_wind-turbines-american-wind-energy-association-renewable-energy)
Question: Are some of our innocent citizens, our county, and city (Freeport) involved in U.N. Agenda 21 through NIDA (Northern Illinois Development Alliance) and Prospering Together?
"One World Order" was stated many times by President George H.W. Bush and reiterated by President Bill Clinton. When you hear terms like Prosperity for All, Sustainable Development, Biodiversity, Social Equity, NGO (Non-Governmental Organizations), PPP, Smart Growth, Growth Management, Comprehensive Planning, Green Ways, Rails to Trails, or Grants - which always have strings attached - then you better listen. When you hear of groups like ICLE (International Center for Leadership in Education), ICMA, Brownfields, and Vision 20/20, you had better do some research.
The term Sustainable Development first originated in a report, "Our Common Future," that was produced by the U.N. World Commission on Environment and Development, authored by Gro Harlem Brundtland, vice president of the World Socialist Party. The term was first offered as official U.N. policy in 1992 in a document called U.N. Sustainable Development Agenda 21.
More than 178 nations adopted Agenda 21, and President George H.W. Bush signed the document for the United States. By endorsing it, he and every nation that did so, too, pledged to adopt its goals. In 1993 President Bill Clinton also "signed on." The federal bureauacracy is to work jointly with state and community systems to "reinvent" government.
If this is successful, U.N. laws will supersede our state laws. This has already been proven with the shutdown of Gibson Guitar Company because they broke an India law for using some of their unfinished wood in 2011. Gun owners also beware because the Obama administration/ Secretary of State Hillary Clinton is working on a U.N. Arms Trade Treaty.
With the assistance of groups like ICLEI (International Council for Local Environmental Initiatives), Sustainable Development is showing up in every county in the nation. With the government teaming up with NGOs such as NIDA and Prospering Together (mentioned above), transparency of dollars and actions become a problem.
Every municipal board member should want to become more informed about this. Learn how many counties pulled out of Agenda 21 as well as the Republican National Committee on January 24, 2012. The Stephenson County Tea Party will show a 45-minute documentary that tells about Agenda 21. David Martindale will then follow with his eye-opening research on how both Stephenson County and Freeport may be involved with Agenda 21. I believe our leaders mean well, but they should at least be aware of what may be transpiring.
Stephenson County Tea Party meeting will be August 9th at Dietz's Old School Apartments, 111 E. Mason Street, Lena, at 6:30 PM.
Bill Dietz Lena, IL
Anthony Glosson, with the Illinois Policy Institute (IPI), wrote concerning a Letter to the Editor that was written by IPI Executive VP Kristina Rasmussen. The letter ran in the July 25, 2012 edition of the Prairie Advocate, but when it was printed the name was mistakenly listed as Kristina Tobin.
The Prairie Advocate regrets the error. For the sake of clarity and our archived issues at www.pacc-news.com, the letter with correction is reprinted below:
Obama's now infamous "you didn't build that" speech may possibly be his most classist and collectivist rhetoric to date. What's more, this speech was delivered after his administration put an end to welfare reform as we know it:
"There are a lot of wealthy, successful Americans who agree with me — because they want to give something back. They know they didn't — look, if you've been successful, you didn't get there on your own. You didn't get there on your own. I'm always struck by people who think, well, it must be because I was just so smart. There are a lot of smart people out there. It must be because I worked harder than everybody else. Let me tell you something — there are a whole bunch of hardworking people out there.
"If you were successful, somebody along the line gave you some help. There was a great teacher somewhere in your life. Somebody helped to create this unbelievable American system that we have that allowed you to thrive. Somebody invested in roads and bridges. If you've got a business — you didn't build that. Somebody else made that happen. The Internet didn't get invented on its own. Government research created the Internet so that all the companies could make money off the Internet."
At first blush, this all probably sounds reasonable to the average observer. But if you're able to see through the smoke and mirrors, you recognize two euphemisms: "somebody," which is really "government," and "give back," which is really "pay taxes."
According to Obama, we owe our success to the state, the collective, and we should willingly "give back" out of appreciation. What the president fails to understand is the government doesn't have any wealth of its own, except what it forcibly takes from individuals and businesses through taxation.
Milton Friedman wrote, "To the free man, the country is the collection of individuals who compose it, not something over and above them. He is proud of a common heritage and loyal to common traditions. But he regards government as a means, an instrumentality, neither a grantor of favors and gifts, nor a master or god to be blindly worshipped and served."
As we approach the 100th birthday of Friedman, we still believe America is great because free men and women are willing to risk everything to pursue their dreams. Not because of the state. And the Institute will continue to promote self-suffiency — the antithesis of government dependence.
Here's to the free man. The individual.
Kristina Rasmussen Executive Vice President Illinois Policy Institute
It's just like Illinois Republicans to cheat Illinois taxpayers.
Years ago the Republican cronies got the state to bankroll a hotel in Springfield. When it went under, the taxpayers got hit with the tab as GOP officials tried to sell their failed investment for pennies on the dollar.
Now the GOP is at it again, this time with Thomson prison.
We have a modern, efficient and secure facility just waiting to be used. Our price should be going up. Instead, local Republicans want the state to sell the taxpayers' investment for pennies on the dollar to appease another GOP big wig.
Look, there's a process to follow here. An independent assessment pegged the prison's price tag at $165 million.
If the federal government needs a new prison, that's the starting bid, not a penny less. It's not only good business sense, it's the law. For too many years, too many Republican cronies cheated the state on real estate deals. That's why we require an outside assessment on deals like this, to protect taxpayers from being undercut.
How dare local Republicans like Bobby Schilling suggest it'd be a good deal to sell it for $70 million less. Rather than selling out Illinois taxpayers, Rep. Schilling should buy a one-way ticket to Virginia, give GOP Congressman Frank Wolf a visit and start sticking up for Illinois taxpayers and their investments.
You see, Mr. Wolf, the vaunted chair of some exaggerated U.S. House subcommittee, gets to play puppet master with the federal prison budget. His tinfoil-hat politics would have you believe there's some grand conspiracy behind the Thomson prison plans, so he won't let the provision pass through his committee, and, to date, Mr. Schilling and the other brave GOP defenders of Illinois tax dollars are afraid to stand up to him.
Instead, they suggest lowering the purchase price so the deal doesn't have to go through Wolf's committee. Doesn't it just scream good government and wise use of taxpayer dollars? These guys will probably offer you a bridge if you give them the time.
I'm all for opening Thomson Prison. Whether it's federal jobs or state jobs, this area needs good jobs. But there's a balance that must exist. The value of this prison, its technological sophistication and efficiency certainly hasn't decreased. Thomson is the state's most modern prison. Perhaps it's ahead of its time. But its time is coming and selling it on the cheap to appease some GOP crony is the last thing we should be doing in Illinois.
I say Illinois should stand its ground, stick to its price and not bow to the sellout shenanigans of GOP Rep. Wolf and Rep. Schilling.
"We are challenged on every hand to work untiringly to achieve excellence in our life work. Not all men are called to specialized or professional jobs; even fewer rise to the heights of genius in the arts and sciences; many are called to be laborers in factories, fields, and streets. But no work is insignificant. All labor that uplifts humanity has dignity and importance and should be undertaken with painstaking excellence. If a man is called to be a street-sweeper, he should sweep even as Michelangelo painted, or Beethoven composed music, or Shakespeare wrote poetry. He should sweep streets so well that all the host of heaven and earth will pause to say, here lived a great street-sweeper who did his job well." Those immortal words are from the late great orator and leader, The Reverend Dr. Martin Luther King, Jr.
What prompted me to share this quote with you? I'm well aware that many of you are familiar with it. In a recent column I wrote of John Stossel being amazed at the numbers of jobs available if a person is willing to do work at a job they perceive as "beneath them".
I wrote asking the question, are we becoming an entitlement society? My email, phone and personal contacts exploded, or as they say, "went viral". Of the hundreds of responses that I received a total of seven were negative, hundreds profusely thanked me for writing it. Many of the comments came from prominent individuals working in the human service industry pointing out the abuse of the system that they see each day. These were the most uplifting, knowing I was right on target. One person wrote of their late grandfather who after losing his job took work that he hated but he refused to accept any hand out or government assistance.
My point then, and certainly the point of Dr. King is work has dignity and never should be below you. I often get comments like "what do you expect me to do work at Walmart or McDonalds"? The short answer is "yah". Two of the greatest success stories in American history – Sam Walton and Ray Kroc – two gentlemen who pulled themselves up by their shoe laces and built empires and many of their employees have grown to great achievement either within those organizations or using them as a springboard to build amazing lives. I would proudly work for either business.
I continue to ache for those who struggle to make ends meet. I joined my dear friends Bobbie Yount, Mayor Gaulrapp, and Pastor Dr. Charles Washington at Mt. Calvary Church of God in Christ on Saturday morning as they distributed food to the needy. Not one person in that line, in my opinion, was abusing the system.
As always, you can reach me, Sally or Barb at 815-232-0774 or e-mail us at firstname.lastname@example.com. You can also visit my website at www.jimsacia.com. It's always a pleasure to hear from you.


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http://www.gfa.org/sponsorWatch the true story of a man who dreamed about a shack by the sewer, then moved into one. Nitya knew God had called him to serve in the slums, he has dedicated his life to working among the people who live there.
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Samsung has patented a system of cellphone and mobile device control that responds to a users gestures, not on the screen as with the multitouch iPhone but as recognised in the space around the handset. Using the cellphone's front-mounted camera, the software recognises preset motions and translates them into on-screen control. For instance, pointing at the screen and then moving the finger could control a mouse or cursor, while rotating the wrist with the hand outstretched might flip an image or layer.
Now I've shouted at my phone when it's been particularly stubborn and refused to send an SMS message or keep hold of a 3G signal, but I don't think I've ever gestured at it. Unlike voice control, Samsung's motion-based interface is going to either require two hands (one to hold, one to wave about like you're guiding a jet in to land) or a table. That immediately limits its usefulness, and could possibly make it inconvenient or just plain embarrassing trying to use your cellphone on, say, a train.
Obviously there's no guarantee that they will implement this in any future handsets, but considering Sony Ericsson have already included basic gesture control in some of their cellphones, this could be a move by Samsung to take control of the technology. In Sony Ericsson's case, music playback on certain phones can be controlled by waving a hand across the device, or calls rejected in a similar fashion. However there is no direct connection between the movement of the hand and something proportionally happening on-screen, as in Samsung's patent.
[via GigaOm]


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I am trying to be a good obedient girl....... But I have a very naughty side.
Not so fast, you must try harder ..... It's my trophy
Damn those sticky buns! http://upload.lushstories.com/1213887435-image.jpg
I have a sexual soul mate, does that count? ☺
Haha, my briefs are sexier
It really isnt a good look, try as I might I can't see the sex appeal. http://upload.lushstories.com/294547607-image.jpg
It's mine :)
Sorry Sarah no offence .... But no
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Product Pathways - Chromatin Regulation / Epigenetics
Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb #9733
PhosphoSitePlus® protein, site, and accession data: H3
No. | Size | Price | ||
9733S | 100 µl (10 western blots) | --- | In Stock | --- |
9733 | carrier free and custom formulation / quantity | email request |
Already purchased this product? Write a Review.
Application | Dilution | Species-Reactivity | Sensitivity | MW (kDa) | Isotype |
W | 1:1000 | Human, Mouse, Rat, Monkey | Endogenous | 17 | Rabbit IgG |
ChIP | 1:50 |
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting, IP=Immunoprecipitation, IHC-P=Immunohistochemistry (Paraffin), IF-IC=Immunofluorescence (Immunocytochemistry), F=Flow Cytometry, ChIP=Chromatin IP
Species predicted to react based on 100% sequence homology: Xenopus, Zebrafish.
- 9733:
- Western Blotting, Immunoprecipitation, IHC / Paraffin, Immunofluorescence, Flow*, ChIP Magnetic, ChIP Agarose
* Product-specific protocol.
Specificity / Sensitivity
Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb detects endogenous levels of histone H3 only when tri-methylated on Lys27. The antibody does not cross-react with non-methylated, mono-methylated or di-methylated Lys27. In addition, the antibody does not cross-react with mono-methylated, di-methylated or tri-methylated histone H3 at Lys4, Lys9, Lys36 or Histone H4 at Lys20.
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of histone H3 in which Lys27 is tri-methylated.
Western Blotting
Western blot analysis of various cell lines using Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb.
Chromatin IP
Chromatin immunoprecipitations were performed with cross-linked chromatin from 4 x 106 HeLa cells and either 10 µl of Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb, or 2 µl of Normal Rabbit IgG #2729, using SimpleChIP® Enzymatic Chromatin IP Kit (Magnetic Beads) #9003. The enriched DNA was quantified by real-time PCR using SimpleChIP® Human GAPDH Exon 1 Primers #5516, SimpleChIP® Human RPL30 Exon 3 Primers #7014, SimpleChIP® Human MyoD1 Exon 1 Primers #4490, and SimpleChIP® Human MYT-1 Exon 1 Primers #4493. The amount of immunoprecipitated DNA in each sample is represented as signal relative to the total amount of input chromatin, which is equivalent to one.
IHC-P (paraffin)
Immunohistochemical analysis of paraffin-embedded human lymphoma using Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb in the presence of non-methyl peptide (left) or K27 tri-methyl peptide (right).
Flow Cytometry
Flow cytometric analysis of human whole blood cells using Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb (blue) and Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (red). Anti-rabbit IgG (H+L), F(ab')2 Fragment (Alexa Fluor® 647 Conjugate) #4414 was used as a secondary antibody. Analysis was performed on cells in the lymphocyte gate.
Confocal immunofluorescent analysis of HeLa cells using Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb (green). Actin filaments have been labeled with DY-554 phalloidin (red).
Tri-Methyl Histone H3 (Lys27) (C36B11) Rabbit mAb specificity was determined by peptide ELISA. The graph depicts the binding of the antibody to pre-coated tri-methyl histone H3 (Lys27) peptide in the presence of increasing concentrations of various competitor peptides. As shown, only the tri-methyl histone H3 (Lys27) peptide competed away binding of the antibody.
The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination (1). Histone methylation is a major determinant for the formation of active and inactive regions of the genome and is crucial for the proper programming of the genome during development (2,3). Arginine methylation of histones H3 (Arg2, 17, 26) and H4 (Arg3) promotes transcriptional activation and is mediated by a family of protein arginine methyltransferases (PRMTs), including the co-activators PRMT1 and CARM1 (PRMT4) (4). In contrast, a more diverse set of histone lysine methyltransferases has been identified, all but one of which contain a conserved catalytic SET domain originally identified in the Drosophila Su(var)3-9, Enhancer of zeste, and Trithorax proteins. Lysine methylation occurs primarily on histones H3 (Lys4, 9, 27, 36, 79) and H4 (Lys20) and has been implicated in both transcriptional activation and silencing (4). Methylation of these lysine residues coordinates the recruitment of chromatin modifying enzymes containing methyl-lysine binding modules such as chromodomains (HP1, PRC1), PHD fingers (BPTF, ING2), tudor domains (53BP1), and WD-40 domains (WDR5) (5-8). The discovery of histone demethylases such as PADI4, LSD1, JMJD1, JMJD2, and JHDM1 has shown that methylation is a reversible epigenetic marker (9).
- Peterson, C.L. and Laniel, M.A. (2004) Curr. Biol. 14, R546-R551.
- Kubicek, S. et al. (2006) Ernst Schering Res. Found Workshop, 1-27.
- Lin, W. and Dent, S.Y. (2006) Curr. Opin. Genet. Dev. 16, 137-142.
- Lee, D.Y. et al. (2005) Endocr. Rev. 26, 147-170.
- Daniel, J.A. et al. (2005) Cell Cycle 4, 919-926.
- Shi, X. et al. (2006) Nature 442, 96-99.
- Wysocka, J. et al. (2006) Nature 442, 86-90.
- Wysocka, J. et al. (2005) Cell 121, 859-872.
- Trojer, P. and Reinberg, D. (2006) Cell 125, 213-217.
Application References
- Pasini, D. et al. (2010) Nucleic Acids Res 38, 4958-69. Applications: Western Blotting, Chromatin IP.
- Kim, K.Y. et al. (2011) Proc Natl Acad Sci U S A , . Applications: IF-IC (In Cells).
- Peach, S.E. et al. (2012) Mol Cell Proteomics 11, 128-37. Applications: Chromatin IP.
- Ohhata, T. et al. (2011) Genes Dev 25, 1702-15. Applications: Chromatin IP.
- Pasini, D. et al. (2010) Nature 464, 306-10. Applications: Western Blotting, Chromatin IP.
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know!
Companion Products
- 9723 Mono-Methyl-Histone H3 (Lys4) Antibody
- 9725 Di-Methyl-Histone H3 (Lys4) (C64G9) Rabbit mAb
- 9727 Tri-Methyl-Histone H3 (Lys4) Antibody
- 9755 Di-Methyl-Histone H3 (Lys27) Antibody
- 9715 Histone H3 Antibody
- 3147 Ezh2 (AC22) Mouse mAb
- 4905 Ezh2 Antibody
- 3737 SUZ12 (D39F6) XP® Rabbit mAb
- 7071 Phototope®-HRP Western Blot Detection System, Anti-rabbit IgG, HRP-linked Antibody
- 7074 Anti-rabbit IgG, HRP-linked Antibody
- 7720 Prestained Protein Marker, Broad Range (Premixed Format)
- 7727 Biotinylated Protein Ladder Detection Pack
- 7003 20X LumiGLO® Reagent and 20X Peroxide
- 8112 SignalStain® Antibody Diluent
- 8114 SignalStain® Boost IHC Detection Reagent (HRP, Rabbit)
- 9006 ChIP-Grade Protein G Magnetic Beads
For Research Use Only. Not For Use In Diagnostic Procedures.
Cell Signaling Technology® is a trademark of Cell Signaling Technology, Inc.
This antibody is developed, validated, and produced by CST using in part technology under license (granting certain rights including those under U.S. Patent No. 5,675,063) from Epitomics, Inc.


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regional news
News stories tagged with "potsdam"
Visitors: Composer Thomas Albert and Son, Violinist Matthew Albert Come To Crane Festival of New Music
Nov 02, 2001 — The Crane School of Music hosts its annual Festival of New Music with a guest composer and one of the most exciting young ensembles performing today--eighth blackbird. Todd Moe talks with visiting composer Thomas Albert and his son, Matthew, who's the violinist with eighth blackbird. Go to full article
Faure Requiem performed in Memory of September 11 Victims
Oct 25, 2001 — This evening at seven, North Country Public Radio presents a performance by musicians from the Crane School of Music at SUNY Potsdam, recorded three weeks ago as part of a memorial concert for victims of last month's tragedy. Joel Hurd talks with Daniel Gordon, who conducted the Crane Chorus and Orchestra, along with members of the Potsdam Community Chorus and faculty and students of the Crane School of Music, in the October 3 concert. Go to full article
Sen. Clinton Addresses Potsdam Town Meeting
Oct 22, 2001 — About a thousand people attended a town meeting with Senator Hillary Clinton on Saturday at SUNY Potsdam. It was part of the senator's tour of the North Country. Martha Foley reports. See links below for additional audio from the town meeting. Go to full article
Local Government Conference Focuses on Spending
Oct 12, 2001 — While the Governor is lobbying Washington for federal aid, local governments are assessing their own spending. The problem was on everyone's mind at the North Country Local Government Conference this week at SUNY Potsdam. David Sommerstein reports. Go to full article
People: Lisa Vroman, Broadway Diva
Oct 12, 2001 — Soprano Lisa Vroman returns to the North Country Saturday, October 13 with a concert, "Broadway Classic", at SUNY Potsdam's Helen M. Hosmer Concert Hall. Todd Moe chats with Lisa Vroman and her music director, Brad Carroll. Go to full article
Vermont Gov. Dean Keynotes Local Government Conference
Oct 11, 2001 — Vermont Governor Howard Dean told North Country leaders that the best projects come from the local level. Dean was the keynote speaker at SUNY Potsdam's 10th Annual Local Government Conference. David Sommerstein reports. Go to full article
Local Government Conference in Potsdam
Oct 09, 2001 — Martha Foley talks with Potsdam Mayor Ruth Garner about the 10th Annual Local Government Conference, at SUNY Potsdam. Wednesday's Conference theme is "Managing Local Government: Listening, Learning, Leading," and Vermont Governor Howard Dean will be the keynote speaker. Go to full article
Commentary: Thoughts on the 9/11 Disaster
Sep 25, 2001 — Rosemary Kriescher is a writer and lives outside Potsdam, NY. Go to full article
Baptist Group Outfits Disaster Relief Truck
Sep 21, 2001 — Jody Tosti reports on a statewide effort by the American Baptist Men's organization to outfit a disaster relief tractor trailer. Local donations to support the project are being taken at the First Baptist Church in Potsdam. Go to full article
Commentary: Thoughts on the 9/11 Disaster
Sep 21, 2001 — More listener reflections on the events of the past week-and-a-half. Today we hear from Ray Toland, a 20-year veteran of the Army Signal Corps. Go to full article
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Patch to pydoc (partial) to handle encodings other than ascii
Hello Pythonists:
I am using SPE as python IDE on Windows, with Python 2.5.1 installed (official distro). As my mother tongue is Spanish, I had documented some modules in it (I now, I should have documented all in English, except if I were 110% sure than nobody else would read my docs, but they are only for in-house use). When I tried to use the pydoc tab that SPE attaches to every source file, I only found a message saying that my accented text coud not be decoded. Browsing the SPE's sources, I found that pydoc's HTMLDoc class could not handle the non-ascii characters. Then patched the Doc's class (the parent of HTMLDoc) code to look for the encoding declared in the source of the module to document, and (in HTMLDoc) decode the source with it. As the HTML file writer function used the same class and choked when writing the file, reencoded the text with the same encoding on writing. As I could not find the mail of pydoc's maintainer (the source code states that the autor is Ka-Ping Yee, but the original date is from 2001, and I could not find if he is still maintaining it), I want to make this patch available so can be possible to use pydoc on non-ascii sources (at least to generate programmatically HTML documentation). If the solution is useful (please don't hesitate in criticize it), may be can be incorporated on a future pydoc version. I don't know how to make a patch file (I usually don't do co-op programming, but use to code as a hobby), but of course I don't even think of sending 90 k of code to the newsgroup, so I am sending the modified code here, with the indication of where do the modifications: After line 323, replace if inspect.ismodule(object): return self.docmodule(*args) with: if inspect.ismodule(object): remarks = inspect.getcomments(object) start = remarks.find(' -*- coding: ') + 13 if start == 12: start = remarks.find('# vim:fileencoding=') + 19 if start == 18: if inspect.getsource(object)[:3] == '\xef\xbb\xbf': self.encoding = 'utf_8' else: self.encoding = sys.getdefaultencoding() else: end = remarks.find(' ', start) self.encoding = remarks[start:end] else: end = remarks.find('-*-', start) self.encoding = remarks[start:end].strip() return self.docmodule(*args) After the line 421 (moved to 437 with the previous insert), insert title = title.decode(self.encoding) contents = contents.decode(self.encoding) And finally replace line 1491 (now 1509): file.write(page) with: file.write(page.encode(html.encoding)) The code don't solves the encoding issue on consoles (just try to document utf-8 sources and see what funny things appears!), but if the approach can help, may be something can be worked to use it in a general way (I just don't know hoy to get the console encoding, and I don't use consoles most of the time). Hope that this can help to some other non-ascii user like me. Cheers (and sorry for the english). Walter Gardella |
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Background: Founded in the 12th century, the Principality of Muscovy, was able to emerge from over 200 years of Mongol domination (13th-15th centuries) and to gradually conquer and absorb surrounding principalities. In the early 17th century, a new Romanov Dynasty continued this policy of expansion across Siberia to the Pacific. Under PETER I (ruled 1682-1725), hegemony was extended to the Baltic Sea and the country was renamed the Russian Empire. During the 19th century, more territorial acquisitions were made in Europe and Asia. Repeated devastating defeats of the Russian army in World War I led to widespread rioting in the major cities of the Russian Empire and to the overthrow in 1917 of the imperial household. The Communists under Vladimir LENIN seized power soon after and formed the USSR. The brutal rule of Josef STALIN (1928-53) strengthened Russian dominance of the Soviet Union at a cost of tens of millions of lives. The Soviet economy and society stagnated in the following decades until General Secretary Mikhail GORBACHEV (1985-91) introduced glasnost (openness) and perestroika (restructuring) in an attempt to modernize Communism, but his initiatives inadvertently released forces that by December 1991 splintered the USSR into 15 independent republics. Since then, Russia has struggled in its efforts to build a democratic political system and market economy to replace the strict social, political, and economic controls of the Communist period. While some progress has been made on the economic front, recent years have seen a recentralization of power under Vladimir PUTIN and an erosion in nascent democratic institutions. A determined guerrilla conflict still plagues Russia in Chechnya.
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Although the average contract interest rate fell for many types of loans, mortgage application volume fell - the MBA points out that Columbus Day may have had an impact on the data.
One Bank of America employee has been charged with a scheme that put over $1 million in his pocket.
If you follow the money at several major foreclosure mill firms, the abuses being discovered at various levels are astounding. One state is investigating, will others follow?
When it was discovered that Eric Holder misstated facts about the Mortgage Fraud Task Force, the DOJ initially issued a press release to correct the record, but has now made the situation worse by editing the original
Two arrests are finally set to be made in JPMorgan's "London Whale" case wherein the bank allegedly covered up $6B in losses - will more arrests follow?
Eric Holder has overstated facts about the mortgage fraud task force formed to seek out and punish wrongdoing, raising additional questions about the crisis.
Local governments in California are known to launch experiments, but invoking eminent domain on underwater mortgages is raising questions and eyebrows across the nation.
Former Bank of America staff members are coming forward, alleging bank policies that forced employees to lie to homeowners and in some cases, illegally foreclose.
Wells Fargo has taken a harsh tone in the case of a homeowner who sent in too much money one month in an effort to get ahead during the trial period of his loan modification.
MERS, once blamed for the entire housing crash, is now being affirmed by judges - could more courts and more states rule in favor of MERS as the tides turn?
MERS, once blamed for the entire housing crash, is now being affirmed by judges - could more courts and more states rule in favor of MERS as the tides turn?
MERS has been the target of many lawsuits from counties claiming unpaid fees, but judges are more frequently ruling against plaintiffs and overturning cases in appeals courts. Is the tide turning?


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Frank Beamer on LB Bruce Taylor's injury: 'It's a tough loss'; plus more info on the Lisfranc sprain
Virginia Tech coach Frank Beamer couldn't sugarcoat it. Losing linebacker Bruce Taylor for the season to a foot injury is a big deal.
"It's a tough loss," Beamer said on his Monday teleconference. "He's played a lot of plays and made a lot of plays. Very smart guy. Gets us into right things. So it's a tough one."
Taylor left the Boston College game Saturday with a foot injury. Monday, the school confirmed the worst: it's a Lisfranc injury, a sprain of the mid-foot, that will end his season. He'll have surgery this week.
Taylor is the team leader on defense, which will be tough to replicate, but he was a play-maker too, one who was on track to lead the Hokies in tackles for a second straight season.
"I think the plays he's made and the number of tackles and sacks, all those things, it's a tough, tough loss for us," Beamer said.
Beamer said senior Barquell Rivers and sophomore Jack Tyler will take Taylor's place.
"We've got a lot of confidence in both those guys," he said.
There was no other significant injury news Monday. Trainer Mike Goforth, who made a rare appearance on the teleconference to talk about Tech's rash of injuries, said he doesn't expect any of the other injuries to keep players out Saturday at Duke.
He said late Saturday night that defensive end James Gayle (ankle) and cornerback Jayron Hosley (hamstring) should be ready to play.
Linebacker Alonzo Tweedy (ankle), who was in a boot after the game, has also made progress.
"He looked good yesterday and was looking even better today," Goforth said. "It's just a matter of how he progresses through this week."
Some other quotes and notes from today's teleconference:
- Goforth gave some pretty good details about Taylor's injury. The Lisfranc is a mid-foot sprain. "If you were to look at it like it was a hand or wrist, your hand bones, it's where it meets the wrist bones. That's what it is. It's down from the ankle and before you get to the toes." It's serious because that's a pressure point for the foot. That's why it was painful for Taylor to push off.
- It's the same injury LB Jeron Gouveia-Winslow had two weeks ago. That's a coincidence. "It's bad luck," Goforth said. "And it's not as rare as you think it is. It's out there quite a bit in the sports medicine literature. It's probably the No. 1 most undiagnosed or misdiagnosed injury in the emergency room. … So luck's not our side right now."
- Goforth said in 2006, Jahre Cheesman, Brett Warren and Cam Martin all had the injury. Not all three required surgery.
- Taylor's will. Goforth said he'll probably undergo what's called a "tight rope" procedure, which is progressive for this kind of injury. I'll let him describe it: "They don't have to put screws all the way through the joint. So it's kind of a filament-type material that goes around the two bones and holds the joint together." It's the same procedure Gouveia-Winslow had.
- Goforth said Taylor will be non-weight bearing for 6-8 weeks before starting underwater treadmill and anti-gravity treadmill rehab work. Taylor will be limited in the spring, but Goforth expects a full recovery for the summer and next year. "We've had good results with them here," he said.
- Lisfranc used to be much more serious than it is now. Many will remember that former Tech running back Kevin Jones' career with the Lions was never the same after the injury in 2006. But the surgical procedures have advanced.
- Goforth said the Hokies have had only one player not make it back from the injury. "Other than that, we've had great results," he said. "Sometimes it does take a little longer than expected, so there's really no cook book that you can follow with this. But we'll take it real slow in the spring. (Taylor and Gouveia-Winslow) are two veterans and don't necessarily need to get out there and beat it up for 15 practices. We'll have to see how they are in late-February."
- One last thing about injuries. Taylor's potential replacement, Rivers, suffered a torn quadriceps tendon in the offseason of 2010. Goforth said he's recovered well from it. "You have to realize when you tear that tendon, it will forever be shortened," he said. "Your body just doesn't respond well to taking a piece of that tendon out and trying to re-attach it. So he's having to overcome that. And he'll always have some tendinitis in that leg and some issues with his flexibility. But he's made a great recovery. Obviously, mentally, he's still sharp as he needs to be. And I think his veteran status is paying off."


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paint can trick-- rubber band
Related Pins:
Use Rubber Bands to Keep Clothes on the Hanger
When painting and dipping your brush straight into a paint can – Place a rubber band around the open can so you can wipe the excess paint off the brush and not the side of the can every time you dip. This keeps the can's lip clean – no build up of paint to have to clean up.
Use $3 glasses, rubber bands, and spray paint to make a beautiful candle holder
Rubber Band as Earring Backing
triangle rubber stamps from www.citoyennes.et...
The Rubber Band Trick - If you need to remove a nail, criss-cross a couple of rubber bands over the top of the hammer before using the hammer's claw. The rubber bands will protect the surface that you're removing the nail from.


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Wild Webisodes: Living in the MomentPosted: Tue 06/26/2012 11:00 AM
It's Week 4 of our Oprah's Book Club 2.0 journey with Wild author Cheryl Strayed, and Oprah and Cheryl are discussing what state of mind she was in after four weeks alone on the Pacific Crest Trail. Find out what Cheryl says she learned about living in the moment. Plus, Cheryl reveals her favorite way to read a book. Oprah's full interview with Cheryl airs July 22 on "Super Soul Sunday." Tune in to OWN, or watch the simulcast on Oprah.com, Facebook.com/OWNTV or Facebook.com/SuperSoulSunday. How to participate in Oprah's Book Club 2.0 Advertisement
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63 USA Today | Scott Bowles He hasn't mastered the craft yet, but M. Night Shyamalan may be on to something with this action-movie thing. Read full review
60 Movieline | Stephanie Zacharek Completely harmless and inoffensive, and at the very least, Shyamalan appears to be having a little fun here. Read full review
50 Philadelphia Inquirer | Carrie Rickey Unfortunately, this all proceeds at a supersonic tempo, with Shyamalan's directorial finger stuck on the fast-forward button. Significant plot points whiz by in this movie equivalent of speed-dating. Read full review
50 The Globe and Mail (Toronto) | Liam Lacey The story is a much more serious problem, a run-on, overstuffed narrative that feels like a very long prologue for a climax that never comes. Read full review


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