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Villanova gets NSF grant for acoustic technologies research
- Peter Key
- Staff Writer
Villanova University has gotten a federal grant for some very sound research.
The university's Center for Advanced Communications has received a two-year, $600,000 Partnerships for Innovation grant from the National Science Foundation to advance the use of acoustic and ultrasound technologies in medicine and industry.
The technologies can be used to produce images and data profiles of everything from hearts to heavy machinery. They can reveal how well something is functioning and show potential problems, such as small cracks in wind-turbine blades, before they become big ones.
"It's the same issue, whether you're dealing with machinery or the human body," said Moeness Amin, who directs the CAC.
The CAC's partners on the grant include:
• Bucknell University, which is researching acoustic-source tracking;
• Gwynedd-Mercy College, which offers training in sonography for diagnostic applications through its School of Allied Health Professions;
• Ben Franklin Technology Partners of Southeastern Pennsylvania, which will help the CAC and its partners find area businesses that can assist with the research funded by the grant and/or commercialize technology resulting from the research;
• The Naval Sea Systems Command, which will make the facilities at its Acoustic Complex available for research under the grant;
• And Siemens AG, which will help researchers understand the needs of the health-care industry.
As the lead institution on the grant, the CAC is responsible for distributing money from it. Amin said the center plans to fund the research that Bucknell and Gwynedd-Mercy are doing and reimburse Ben Franklin for the time it spends working with the partnership.
Peter Key covers education, technology, utilities and venture capital for the Philadelphia Business Journal. Read his blog postings here.
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Richard Dawkins: Bigot and Coward
Atheist blowhard Richard Dawkins never has the least hesitation in bashing Christians and Jews, but when the subject of Islam comes up, at least when he is being interviewed by Al-Jazeerah that will blast his comments throughout the Islamic world, well that is another matter:
While you may not agree with the views of the new breed of aggressive atheists who have emerged in recent years you have to admire their courage for bravely standing up and speaking truth to power against the various religious institutions whose integrity they seek to undermine. No matter what consequences they might face, they aren't afraid to lay out their case against religion in terms that are often harsh and sure to offend.
Here is an example from an article called Facing uncomfortable truths:
In a recent Al-Jazeerah interview, Richard Dawkins was asked his views on God. He argued that the god of "the Old Testament" is "hideous" and "a monster", and reiterated his claim from The God Delusion that the God of the Torah is the most unpleasant character "in fiction".
As you can see, Dawkins has no trouble attacking the Hebrew God in a most direct and uncompromising manner. No atheist wallflower he.
Asked if he thought the same of the God of the Koran, Dawkins ducked the question, saying: "Well, um, the God of the Koran I don't know so much about."
How can it be that the world's most fearless atheist, celebrated for his strident opinions on the Christian and Jewish Gods, could profess to know so little about the God of the Koran? Has he not had the time? Or is Professor Dawkins simply demonstrating that most crucial trait of his species: survival instinct.
Whoops. It's funny how these confident, cocksure prophets of atheism-who barely have time to take a breath between slamming the tenets of Christianity and Judaism-often get curiously tongue-tied and shy when the subject of Islam comes up. The idea that Dawkins doesn't "know so much about" the God of the Koran is absurd. Of course he knows about Islam. And the same disdain and disregard that he has for Judaism and Christianity should surely apply to Islam as well.
Comedy Central Cowers Before Jihadists While Mocking Christians
The cowards at Comedy Central who censored South Park after receiving death threats from Jihadists, as I detailed here and here, now show their "courage" by announcing a new show mocking Christ. My friend Jay Anderson at Pro Ecclesia gives us the details:
"Fresh off of heavily editing a depiction of Mohammad in "South Park" following threats from practitioners of the "Religion of Peace", the "edgy" comedy network, Comedy Central, shows its artistic "courage" in announcing a new series blaspheming Jesus Christ:
Comedy Central might censor every image of the Prophet Muhammad on "South Park," yet the network is developing a whole animated series around Jesus Christ.

subset: commoncrawl


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Sunny Anderson
Wings Three Ways
About Sunny Anderson
Sunny finds inspirational recipes from home cooks in Home Made in America and makes down-to-earth meals in Cooking for Real. More
Sunny Anderson's Links:
Sunny's Extras
Tailgate with Sunny
Try one of Sunny's crowd-pleasing recipes at your next tailgate.
Big Game Recipes
Recipes by Sunny Anderson
Browse Episodes
Pancakes and Pierogi
Home Made in America with Sunny Anderson
Babycakes Food truck is the only pancake food truck in all of America, and Sunny heads to Chicago to meet the owner, Leah. She reveals her Rainbow Silver Dollar Pancakes that inspired the truck, and also shows Sunny her Strawberry Margarita and Sausage Apple Pancakes that sell like, well hotcakes. Then Sunny is on the Bethany, Conn., farm of Kathleen to get the homemade Pierogi recipe, which was passed down from her grandmother, that now hundreds flock to the farm to taste, alongside Kathleen's homemade Veggie Chili.
Buffalo Chicken Lasagna and Four-Layer Cheesecake
Home Made in America with Sunny Anderson
David's firehouse Buffalo Chicken Lasagna recipe is so amazing, thousands of firefighters across the country clamor for the recipe, and Sunny heads to River Grove, Ill., to get it! Then Sunny meets Jeneen of Queens, N.Y., to get the recipe for her Four-Layer Cheesecake that is so good, Jeneen, a singer/baker, sold it at her gigs around New York to raise money to cut her first album.
Arancini and Swordfish
Home Made in America with Sunny Anderson
Sunny's in Brooklyn to get the home recipe of Dave's Arancini al Ragu. Dave perfected his recipe for this Italian fried rice ball in Sicily, and now is the owner of Arancini Brothers. And while at the restaurant, Sunny gets Dave to reveal another recipe, the Bianco, Rosso Verde Arancini. Sunny then heads to Somers, N.Y. to meet Lucille, whose recipe for Swordfish Balls has been passed down in her family for 100 years and is a Christmas tradition.


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A Nueces County jury on Monday found a Corpus Christi man guilty of murder related to a November fatal shooting at a convenience store.
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Submitted By: Luke Mehall on Apr 9, 2013
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Come celebrate the print release of Climbing Out of Bed by Luke Mehall, at Maria's Bookshop in Durango, Colorado. This is Mehall's first book. He is also the publisher of The Climbing Zine. The author will read from the book, and copies will be available. Plus, more fun and surprises!


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Rise and Shine Rooster Pajamas for Women
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Home Spa Treatments, Foot Care Give the Gift of Healthy Feet!


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It's all bags: Botkier, Lulu Guinness, Rafe, and more. A little lingerie and accessories like belts and hats fill out the offerings.
Products: bags, lingerie, swimwear, women's clothes
Products: bags, lingerie, swimwear, women's clothes
more on luckymag.com
The 18 Most #FOMO-Inducing Instagrams of Fashion Month
Lucky for you, we filtered through the multitude of photos to find the absolute best Instagrams from this fashion month.
Seven Style and Beauty Secrets We Learned This Week
Click through for right way to apply dry shampoo, stunning Paris street style and more.
The Grand Budapest Hotel: Shop The Film's Stunning Color Palette
Using a heady mix of pastels, neutrals and jewel tones, Anderson quite literally paints a beautiful portrait of the (fictional) Eastern European Repub…
Santigold Created a Makeup Collection for Smashbox and It's Out Of This World!
We chatted with the singer for the full scoop!
11 'It'-Status Items Our Editors Are Buying For Spring
If you only buy one new thing in the new few months, we strongly suggest one of these pieces. Click through for your ultimate spring shopping list!


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UnderGear Coupon: 15% off + Free Shipping on Any Order
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See more active UnderGear Coupons or deals and coupons filed under: Apparel
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Michael Sigman: Picking up on the Supreme Court's gargantuan gift to Republican candidates in the 2010 Citizens United decision, the Mittster went all Soylent Green on an Iowa heckler, opining, "Corporations are people, my friend… of course they are."
Nary a Clue
Obama Policies Ensure the GOP Never Has to Defend Bush
Tina Dupuy: Mr. Bush announced he had to cancel his first trip to Europe since he published his memoir and admitted to authorizing waterboarding. There were calls for large protests and threats of investigations, so Mr. Bush opted (as always) to stay in Texas. So, we ignore him. The GOP doesn't mention him. And the rest of the world wants to lob a giant shoe at him. To make this all worse, the only person who seems to be toeing the line for Bush is…Barack Obama.


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» Tools
» Build Relationships
» Love Your Child Challenge
Love Your Child Challenge
Moms love their children, there's no doubt about that. But, in the busyness of our mom-life, we can forget to do the little things that let our children know how we feel. So take our NEW Love Your Child Challenge. And, share your love with our cute iMOM Love Notes.


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Files | Size | Format | View |
Ahm2003Oct5Throughput.PDF | 161.5Kb | application/pdf |
Title: | Throughput Measures for Delay-constrained Communications in Fading Channels |
Author: | Ahmed, Nadeem; Baraniuk, Richard G. |
Type: | Conference Paper |
Keywords: | throughput; fading channels; block fading; outage; capacity |
Citation: | N. Ahmed and R. G. Baraniuk,"Throughput Measures for Delay-constrained Communications in Fading Channels," in Allerton Conference on Communication, Control and Computing, |
Abstract: | Fading channels, often seen in wireless systems, provide an unfavorable environment for reliable communications. Current methods for evaluating the performance of fading channels include ergodic capacity and epsilon-capacity. Ergodic capacity quantifies the ultimate reliable communication limit of the fading channel. It is only achievable with infinite coding delay, making it impossible to achieve in practice. epsilon-capacity, achievable with finite coding delay, does not provide a measure of error-free communications performance. Since practical communication systems are delay-constrained, it is possible to retransmit codewords when errors occur. We provide a new analysis framework that accounts for codeword retransmission in the analysis of fading channels. We introduce new measures, maximum zero-outage throughput and maximum epsilon-throughput, that predict the performance of practical systems and show that ergodic capacity and epsilon-capacity are special cases of our definitions. We also provide a measure that characterizes the performance of a system with more complex receiver design, using "incremental diversity" to improve throughput. |
Date Published: | 2003-10-01 |


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Why Won't Markey Agree to Debates He's Already Agreed to, Wonders Boston Herald Why doesn't our local tabloid tell readers when they've erred? By Eric Randall | May 20, 2013 10:34 am
Cooter Is Not Happy with Ed Markey The Duke's of Hazzard star didn't appreciate being uninvited from a fundraiser. By Eric Randall | May 16, 2013 12:11 pm
Confederate Flags Are Your Massachusetts Senate Issue of the Day Ed Markey asked a pro-flag donor to stay away from his fundraiser. By Eric Randall | May 14, 2013 5:06 pm
The Massachusetts Senate Polls Are Sending Mixed Signals Two new polls ... two different snapshots of the race. By Eric Randall | May 9, 2013 11:51 am
Nate Silver Thinks Gabriel Gomez Is Losing Bigtime Forget the polls, says the political prognosticator. By Eric Randall | May 7, 2013 9:08 am
Everyone Raises Money Off the Massachusetts Senate Poll Last week's numbers prompted both Gomez and Markey to plea for cash. By Eric Randall | May 6, 2013 9:21 am
Poll: Gabriel Gomez Does Shockingly Well Against Ed Markey The first poll shows a surprisingly tight race. By Eric Randall | May 3, 2013 12:24 pm
It's Ed Markey vs. Gabriel Gomez The primary results are in. By Eric Randall | April 30, 2013 9:29 pm
The Boston Herald Covers the Race for Senator of Fantasy Land To hear them tell it, last night's Democratic debate was massively interesting. By Eric Randall | April 9, 2013 9:47 am
Ed Markey's Anti-Abortion Past The Globe makes a good point about Markey's criticisms of Stephen Lynch. By Eric Randall | February 28, 2013 2:32 pm


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West Penn P&P Federal Credit Union has 2 locations in Pennsylvania. The credit union serves members from offices in Beaver and Erie. Go to West Penn P&P Federal Credit Union main page.
West Penn P&P Branch Locations
Branches in Pennsylvania Beaver West Penn P&P Federal Credit Union Beaver 1089 Third Street Beaver, PA 15009 Erie West Penn P&P Federal Credit Union Erie 1701 State St Erie, PA 16501 Return to Top of Page.
Special offer to credit union members. See your instant credit report. Also see our daily
credit union news page
Find Local Credit UnionsLook up other Pennsylvania credit unions. Online newspapers and TV stations serving Beaver and Pennsylvania: Akron Beacon Journal, Public Opinion, or view a national listing of newspapers. Thinking of buying a car? See Pennsylvania car dealers listed alphabetically by city. |


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E-mail this product to a friend
Now dad can improve his fathering skills in his own time with 24/7 Dad™ Interactive! An innovative resource for dads, this CD-ROM is a fun, self-paced version of our 24/7 Dad™ program that guides dads on a personal journey to help them develop a customized fathering strategy based on their own self-assessment and the ages/stages of their children. Accessible and engaging, this CD-ROM will give dads the tools they need to connect with their kids!
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24/7 Dad™ Interactive is filled with essential information on a variety of helpful topics, and includes fun, interactive tools - like a Personal Fathering Assistant (PFA) where dads can take notes. Narrarated by three real-life dads of different backgrounds, ethnicities, and family structures, 24/7 Dad™ Interactive is perfect for almost any dad with access to a computer.
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St. Elsewhere: Season 3, Episode 1Playing God: Part 1 (19 Sep. 1984)
(awaiting 5 votes)
Reviews: write review Fiscus gives the new residents a tour of the hospital. A nun must decide whether to disconnect life support when her fellow sister, injured in a car accident, is declared brain dead. After ... See full summary » Director:Bruce Paltrow |
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...CAMPAIGN; GROWTH ENERGY; RENEWABLE FUELS ASSOCIATION; AMERICAN FUEL & PETROCHEMICAL MANUFACTURERS...capacity as Governor of the State of California; KAMALA D. HARRIS...
The Recorder
...1491 In the Supreme Court of the United States On Writ Of Certiorari To The United States...
The Daily Report
LegalZoom provides a way for consumers and small businesses to take care of their legal needs. The company, founded in 2001, says more than 2 million customers have created their own legal documents
LegalZoom's general counsel joined the online legal services pioneer in 2003, attracted by doing something novel in the industry and by the idea of making the law accessible to the middle class and s
Originally Published: The Recorder
LegalZoom's general counsel joined the online legal services pioneer in 2003, attracted by doing something novel in the industry and by the idea of making the law accessible to the middle class and s
...includes a complete loop around Mount Rainier, the highest mountain in Washington state. I understand that one of her eight grandchildren later followed in her...
... United States Court of Appeals for the...Amicus Curiae, American Immigration Lawyers Association, Washington, D.C. ...
... No. 11-36010 United States Court of Appeals for the Ninth Circuit D...
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What Is The Best Over The Counter Drug For Bacteria Vaginosis
Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
Bacterial VaginosisWhere Can I Get More Information? Division of STD Prevention (DSTDP) Centers for Disease Control and Prevention www.cdc.gov/std Order Publication Online at www.cdc.gov/std/pub CDC-INFO Contact Center 1-800-CDC-INFO (1-800-232-4636) Email: firstname.lastname@example.com Website: www.cdc.gov CDC National Prevention Information Network (NPIN) P.O. Box 6003 Rockville, MD 20849-6003 1-800-458-5231 1-888-282-7681 Fax 1-800-243-7012 TTY E-mail:...
Ask the Experts
Bacteria Vaginosis and BlistersHey, first I want to say thank you for taking time out to read and answer my questions. Well after my boyfriend and I have sexual intercourse I developed a sore between my vagina and anus. A day later it turned into a blister and after that it burst...Response from Erik Glenn, M.A.
Chicago Black Gay Mens Caucus
Thanks for your question,There's a few things to unpack here. First off, I wouldn't be looking to BV as the cause of your blister when 1) those symptoms aren't associated with BV and 2) you have strong (other) possibilities that could...
Read more »
my chronic bacterial vaginosis infection seems to be antibiotic resistantWhat can I do to eradicate chronic bacterial vaginosis. I have been having this problem form the past three years,and now it seems to be antibiotic resistant because it does not go away.I have been treated with metro gel and cleosin and neither make...Response from John L. Sullivan, M.D.
University of Massachusetts, Medical School
Chronic bacterial vaginosis should be managed by a Gynecologist with expertise in this area; if you are not satisfied with the care you are receiving you should ask for a referral for a second opinion;JLS....
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Bacterial Vaginosis (BV)Hi! I'm a college student sharing a bathroom with eight other girls in our dorm suite. It has just came to my attention that our suitemate's sister has BV. Is it possible to contract this disease through anything besides sexual contact?...Response from Rick Sowadsky, M.P.H.
Nevada State Health Division AIDS Program
Thank you for your question. Bacterial Vaginosis (BV) is caused by a change in the bacterial flora of the vagina. In women who have BV, bacteria such as G. vaginalis, Mycoplasma hominis, and certain anaerobic bacteria, are found at abnormally high...
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over the counter medshow come people taking hiv meds can not take over the counter meds?...Response from Nelson Vergel, B.S.Ch.E., M.B.A.
Program for Wellness Restoration
Who told you that? That is not true...
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New Drugs In The Pipeline Vioxx In The Headline??
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New Drugs In The Pipeline Vioxx In The Headline??Most everyone knows about the latest Drug/Pharmaceutical scandal, and many people are becoming aware of how clinical trials are skewed ( if it takes 20 trials to get one positive result that is how it... Read more » Help! Drugs or no Drugs? Options?
Posted by hblue23, 4 Replies
Hi.Please excuse the long drawn out story, but I need help and I am scared. I just had a baby, she's 5 months old now. I was on the HIV meds for the pregnancy because it was necessary to protect her and it is known that your immune system is down... Read more » How Long Do Acute Symptoms Last?
Posted by une_fille, 2 Replies
hello, i had unprotected sex with someone i didn't really know six weeks ago. a week later i developed bacterial vaginosis. i was treated with an anitbiotic and then my tongue developed a white fuzzy appearance and was tingling. i thought maybe...
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Experience with Provigal, Issentress or Prevista?
Posted by ScotCharles, 1 Reply
My psychiatrist has prescribed Provigal to boost my energy level and to counter the effects if HIV Associated Dementia. I am to work up to 200 mg twice a day. I am starting with 50 mg twice a day and will increase my intake by 50 mg each week...
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track list
Rihanna Confirms Chris Brown On Track Listing For "Unapologetic"
The pop singer is going for broke with the concept, releasing her official track listing via Twitter today and confirming a track with ex-boyfriend Chris Brown.
Track List For New One Direction Album Leaked
Just two weeks ago, the lead single from their new album Take Me Home was leaked and forced a rush release of the single "Live While We're Young."
"Glee: The Music, The Christmas Album Volume 2″ Track Listing Released!
[photogallerylink id=101489] Is it too early to start planning for Christmas? We know, we know! Halloween hasn't even happened yet, but it's getting harder and harder to avoid the onslaught of winter wonderlands. Stores have […]


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Before a dental procedure, levels of antiepileptic drugs (AEDs) should be measured and adjusted based on the individual patients history. The dental team should be informed about the patients seizure type and first aid.
Seizure-precipitating factors, such as sleep deprivation or alcohol intake, should be avoided before the procedure.
Methohexital was compared to local anesthetic in conservative dental procedures. Although a seizure occurred in only 1 out of 200 patients, the main disadvantage of its use over local anesthetic is side effects, including tongue movements, coughing, hiccoughs, and prolonged lethargy after the procedure.105
Seizures that occur during or after a dental procedure can occur with N2O104 and methohexital.51 In these studies, seizures most often occurred in patients with undiagnosed epilepsy or those who missed a dose of their antiepileptic medications on the day of the dental procedure.
Other studies demonstrate that N2O and propofol in subanesthetic doses for conscious sedation are safe for mentally handicapped epilepsy patients who undergo dental procedures.45 N2O and propofol are almost always safe in epilepsy patients who are adequately treated with AEDs.
Reviewed and revised April 2004 by Steven C. Schachter, MD, epilepsy.com Editorial Board.
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Quick View The Lost Girls: Three Friends. Four Continents… by Amanda Pressner May 11, 2010 | Kobo Edition (eBook) from $11.99 Jen, Holly, and Amanda are at a crossroads. They're feeling the pressure to hit certain milestones—scoring a big promotion, finding a soul mate, having 2.2 kids—before they reach their early thirties. When personal challenges force them to reevaluate their lives, they decide it's now or never to… See Details $11.99 was
Quick View Lost girls (Versione italiana) by Amanda Pressner May 17, 2011 | Kobo Edition (eBook) | Italian from $13.99 Amanda, Jen e Holly abitano a New York e hanno una vita invidiabile. Giovani donne in carriera, totalmente immerse nei ritmi frenetici della Grande Mela, sono lanciate verso un avvenire che, in qualche modo, pare già scritto: lavoro stabile, matrimonio, figli... Ma è davvero questo quello che… See Details $13.99 was


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March 11, 2014 | United Way Mahoning County's Bob Hannon
March 6, 2014 | Vindy Roundtable; Elsa Higby of Grow Youngstown
April 11, 2013 | Download
Broadcasting from The Vindicator's newsroom, the show will be highlighted by a 10 a.m. visit from Executive Director of The Youngstown Foundation, Jan Strasfeld.
And at 11 a.m., Editor Todd Franko will join Louie for a discussion on various Youngstown topics.
Use the comment form below to begin a discussion about this content.


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This building is listed under the Planning (Listed Buildings and Conservation Areas) Act 1990 as amended for its special architectural or historic interest.
Name: CHURCH OF ST OSWALD
List entry Number: 1201549
The building may lie within the boundary of more than one authority.
National Park: Not applicable to this List entry.
Grade: II
Date first listed: 29-Jul-1950
Date of most recent amendment: Not applicable to this List entry.
The contents of this record have been generated from a legacy data system.
Legacy System: LBS
This list entry does not comprise part of an Asset Grouping. Asset Groupings are not part of the official record but are added later for information.
Legacy Record - This information may be included in the List Entry Details.
BIRKENHEAD SJ2890 HOYLAKE ROAD, Bidston 789-1/6/172 (East side) 29/07/50 Church of St Oswald GV II Parish Church. Largely 1856 by W. and J.Hay but incorporating late medieval tower and with chancel and possibly north aisle added or remodelled in 1882 by W.E.Grayson. Coursed and squared rubble in large blocks, but randomly coursed in north aisle and chancel. Westmorland slate roof with ridge cresting. Nave with west tower, two aisles and chancel. Early C16 three-stage west tower with angle buttresses. Perpendicular stilted moulded arch to west door with drop ended hood-mould over. Frieze of quatrefoil panels and coats of arms over doorway. 3-light window above with ogival hoodmould continuing as string course. 3-light bell-chamber window in third stage. Embattled parapet with corbel table. North aisle has 2-light Decorated window in west wall, and 2 in north wall. Gabled vestry wing dated 1903 projects, possibly incorporating earlier fabric in its west wall. Paired lancet lights in north wall of short chancel, and 3-light Decorated window with hood mould carried on corbel heads to the east. Small foiled lancet in south wall, and parapet with frieze dated 1882. Gabled porch in south aisle, with chamfered archway. Dated 1593 with date of rebuilding, 1856. Stilted arches to 2-light Decorated windows and small side door with hoodmould over. Interior space has been divided by a new screen leaving exposed a nave of 3 bays. Cylindrical shafts to steeply arched arcade. Nave roof with shallow curved principal trusses with collar. Chancel arch carried on corbels. Sedilia in chancel dated 1882: foiled arches on foiliate corbels. Reredos by Salviati, mosaic Last Supper with wood canopy frieze over. Painted roof with angel corbels over choir, the rest boarded. North aisle has 2-light Decorated window in west wall, and 2 in north wall. (The Buildings of England: Pevsner N and Hubbard E: Cheshire: Harmondsworth: 1971-). Listing NGR: SJ2834790252
National Grid Reference: SJ 28347 90252
The above map is for quick reference purposes only and may not be to scale. For a copy of the full scale map, please see the attached PDF - 1201549.pdf
This copy shows the entry on 08-Mar-2014 at 12:39:00.


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Doggy couch surfing website has in-home vacation lodging for dogs
Doggy couch surfing? Website has in-home lodging for dogs when their owners go on a vacation and don't want to coop their pooch up in kennel caging.
Los Angeles
When you travel and have to leave your dog behind, you can call a kennel, hire a pet sitter — or find him a new friend online.
Skip to next paragraphSubscribe Today to the Monitor
The website DogVacay debuted in New York and Los Angeles in March and, just in time for the summer travel season, is now available throughout the United States and Canada.
The site lets pet owners look up hosts in the area who will care for a dog in their own homes, giving a pet the food, exercise and attention you would give if you stayed home — sort of a doggy version of couch-surfing, for an average price of $25 to $30 a day.
Related: Are you a Helicopter Parent? Take our quiz to find out!
Hosts are checked out and interviewed by DogVacay and every owner and dog is encouraged to meet the host.
The Santa Monica-based company was founded by Aaron and Karine Nissim Hirschhorn. In two months it has grown to over 4,000 hosts in two countries and from five employees to 13, Hirschhorn said.
Valerie Steiger's Shih Tzu mix named Joey was just 3 months old when she had to leave for a two-week Thailand trip in February. Joey has been back four or five times since, said Steiger, whose job as a life coach keeps her on the road.
Her host has a couple of dogs and Joey enjoyed them so much, he was depressed when he got home and didn't have any playmates, Steiger said.
"She was wonderful. I was talking to Joey (through a cell phone app) from Thailand. She took pictures of Joey on an iPhone, she took a video of him zipping around with his buddy. I didn't ask for any of that. She just did it," Steiger said.
Steiger has used kennels in the past. And there are good ones, she said, but dogs are still kept in crates or cages for several hours each day. "It's like they are in jail."
Knowing where her dog is and what he's doing is important to her because "this is my baby. I'm leaving my baby behind," Steiger said.
Hirschhorn and his fiance went on a trip to visit family in 2010 and left their dogs Rocky and Rambo in a kennel. "Rocky came back a little off. She was not acting herself. She was sheepish and hiding under the desk. She is normally a happy, happy dog," he said.


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Uttar Pradesh Urdu Teacher Merit List 2013 is likely to be made available. The candidates who are looking for this, they can get it through this website. We provide it to you shortly in few days. The candidates who have apply for this recruitment of Uttar Pradesh Basic Education Parishad, the selection of candidates will be based on Merit List.
Basic Education Parishad, Allahabad, Uttar Pradesh has published a Notification for recruitment of 4280 Posts of Urdu Teacher to improving the Urdu Culture in the State. Urdu is oldest Language Mostly used in India. The recruitment Department of Parishad invites the Applications from the interested candidates who are eligible for this recruitment. Posted by http://hindustanjobsportal.blogspot.com. Candidates can apply online through the official website of Department. A large number of interested candidates are appeared in this recruitment till now. The Last Date for apply is 1st September 2013.
This recruitment will be commenced on basis of Merit List. The department of Basic Education will create it according to the aggregated marks in High School, Intermediate and Graduation on a State level. Then the eligible and selected candidates will recruit in the schools/ colleges where Urdu Language is compulsory to teach.
The candidates who are looking for merit list 2013 for Recruitment of Urdu Teacher they are advised that we will publish it in few next day please stay in contact with us through this website with effortless way. Visit us regular.


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Cedar Rapids Weather
9 Who Care: Kirt SickelsBy Nadia Crow, Reporter
WEST LIBERTY, Iowa - After serving our country, servicemen and women come home to an uncertain future. Some deal with severed limbs, post-traumatic stress disorder, and other issues that prevent them from having a normal life. West Liberty's Kirt Sickels is a man who strives to honor and help those veterans.
West Liberty volunteer firefighter Kirt Sickels captured cellphone video of a fire on January 21st when the shooting range just next door to his home went up in flames. "You could hear it. It sounded like firecrackers going off," said nominator Mindy Sickels. His daughter Mindy was there when he got the call. Never one to shy away from helping out the helpless, Kirt suited up and fought the flames. "That's kind of a real excitement for me the pager goes off and my adrenaline flows and I'm like watch out," said nominee Kirt Sickels. By night, a volunteer firefighter; but during the day, his true passion is working for veterans at the VA Hospital in Iowa City and at various events around Eastern Iowa. Kirt Sickels and his daughter Mindy work to fill up care packages for veterans. Bags from his annual golf outing, the TEE Tournament in its 20th year for disabled veterans, the blind and the paraplegic who come out each year to play. It's one of the many ways Kirt dedicates his life to those who've served. "It's engraved in him its part of who he is," said Mindy Sickels. He works behind the scenes at Veterans Day services, memorial day parades, or other events. A veteran himself, Kirt works to protect those who protected our freedom. "I don't think we can do enough for these gals and guys and its been my drive to figure out how we can do more," said Kirt Sickels. And Kirt does more than his fair share for those with missing limbs and others with problems you can't see from the outside. He says they all share a longing to be a part of something that bonds them together. "They havent been out of their homes in two and a half years havent gone anywhere and you give them an opportunity to have something that they belong to and then they flourish," said Kirt Sickels. He's got a national award named after him and other signs his fellow veterans respect and appreciate him. But Kirt doesn't want this attention. He doesn't want the spotlight. He wants more people to do more for these guys. Veterans he calls the unsung heroes. But his daughter Mindy has an idol of her own. "He's my living hero," said Mindy Sickels. Conversation GuidelinesBe KindDon't use abusive, offensive, threatening, racist, vulgar or sexually-oriented language. Share KnowledgeBe truthful. Share what you know and what you are passionate about. Stay focusedPromote lively and healthy debate. Stay on topic. Ask questions and give feedback on the story's topic. Report TroubleHelp us maintain a quality comment section by reporting comments that are offensive. If you see a comment that is offensive, or you feel violates our guidelines, simply click on the "x" to the far right of the comment to report it. read the full guidelines here » Commenting will be disabled on stories dealing with the following subject matter: Crime, sexual abuse, property fires, automobile accidents, Amber Alerts, Operation Quickfinds and suicides. |
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Definition of excitable in English:
Syllabification: ex·cit·a·blePronunciation: /ikˈsītəbəl
- 1Responding rather too readily to something new or stimulating; too easily excited: Chip could be a bit wayward and excitableMore example sentences
- The easily excitable man with the curly hair has decided to join myself and Jared in this little experiment and has already posted his first song.
- The most easily excitable ones immediately interpreted his comments to mean that he thought women were dumb.
- The Artisan Child is highly active, easily excitable, likes taking risks and getting into mischief.
temperamental, mercurial, volatile, emotional, sensitive, high-strung, unstable, nervous, tense, edgy, jumpy, twitchy, uneasy, neurotic• informal uptight, wired - 1.1(Of tissue or a cell) responsive to stimulation.More example sentences
- The authors review excitable membrane potentials and neurotransmitters.
- Heart cells, like other electrically excitable cells, become inexcitable for a brief period after each action potential.
- Voltage-sensitive Na + channels are responsible for the upstroke of the action potential in excitable cells.
- More example sentences
- Paradoxical CNS stimulation results in talkativeness, excitability, restlessness, anxiety, mania, hyperactivity, delirium, and rage.
- Euphoria is gradually displaced by restlessness, extreme excitability, insomnia, and paranoia - and eventually hallucinations and delusions.
- Using police strategies and crowd simulations to inspire protest tactics, Nold relies on the excitability of crowds and offers tools for civil disobedience including sonic vibration for material disturbance.
- More example sentences
- 'When we hire guys, they know [not to] bring any mental baggage in here,' Koenig says pacing excitably across the dim studio, red wine in hand.
- Moore scrambles around the film like a big shaggy dog, jumping up and knocking things over, excitably putting together all sorts of possible connections.
- The two managed a pretty good Mutt and Jeff routine between them: squat, professorially-maned Rosenbaum prodded and praised excitably while the lean, unflappable director shrugged off analysis and goofed for the crowd.
Pronunciation: /ikˌsītəˈbilitē/
Pronunciation: /-əblē/
More definitions of excitable
Definition of excitable in:- The British & World English dictionary
- The English Synonyms
- The US English Synonyms


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Definition of plasterwork in English:
Syllabification: plas·ter·workPronunciation: /ˈplastərˌwərk
- Plaster as part of the interior of a building, especially covering the surface of a wall or formed into decorative shapes and patterns.More example sentences
- Decorated in pale green, it has decorative ceiling plasterwork, a white marble fireplace and French doors to the back garden.
- Features include mouldings, polished timber floors, high ceilings and decorative plasterwork.
- The house has highly decorated interiors with lavish plasterwork, inlaid floors and exquisite joinery.
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Pronunciation: ˌeksəˈterik
likely to be understood by the general public


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Posted November 13, 2012 on
IT HAS NOT quite lived up to the hope of providing Washington State fans their first bowl since 2003. But coach Mike Leach said during his Tuesday Pac-12 football coaches teleconference that he is not discouraged about the state of the program as Washington State plays its final road game of the season at noon Saturday at Arizona State (TV: Pac-12 Networks).
Original Story:
Washington State Coach Mike Leach Responds to Abuse Allegations
Leach: 'We don't have anything to hide'
110 Sports Podcast: Mike Leach
2013 NFL Draft: Marquess Wilson Leaves Washington State On Bad Terms and with Uncertain Draft Stock
The Traditions of Punishment And Pride
Wazzu to review football allegations
Moos: Amid tumult, recruiting is 'tremendous'
Mike Leach, Washington State Staff Will Be Subject to Pac-12 Investigation Following Claims of Abuse by Marquess Wilson
Pac-12/West Coast news: Mike Leach, Joe Southwick, and more.
Know Your Foe: Washington State
Tuel expected to start against ASU
11.14.2012 Pac-12 Football Podcast – Oregon Outlasts USC
Football Friday on a Thursday, Week 12 2012 Season
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Ranking the 10 Best Hitters in Baseball over the Last 30 Days
By Christopher Benvie ,
One of the most exciting and fun facets of being a fan of baseball is the frequency in which things can change.
At the beginning of the season, Josh Hamilton and Matt Kemp were the best players in the world and nobody could touch what they were doing.
Injuries happen, droughts happen, things change.
Here we stand, post non-waiver trade deadline, ready to kick off the month of August and gear up for a postseason push.
Some players embrace the challenge better than others.
Over the past 30 days, fans have been spectators of some fine baseball. Here is a list of the 10 best batters to emerge in the past 30 games.
Note: Players were only eligible for my ranking if they played in 20-or-more games over the past 30 days.
Somehow, some way, Josh Willingham was not dealt by the Minnesota Twins at the trade deadline. That's a good thing for Twins fans.
In the past 30 days, Willingham has played in 24 games, posting a .273/.387/.636/1.023 batting line.
He has added 24 hits (12 of which were for extra bases coming in the form of 10 home runs and two doubles) while driving in 23 runs, scoring 17 of his own.
His 10 home runs place him in a four-way tie for the most long balls over the past 30 days. Two of the other three players are on this list as well.
The only player omitted (honorable mention, I guess you could say) was Jason Kubel.
Through 25 games in the past 30 days, Miguel Cabrera has posted an impressive .330/.390/.691/1.082 batting line.
He has 31 hits, 14 of which were for extra bases in the form of 10 home runs and four doubles.
Cabrera has driven in 22 runs while scoring 21 of his own.
As you've likely noticed, he is tied with Josh Willingham and two others for the most home runs over the past 30 days.
The St. Louis Cardinals are playing pretty great baseball lately, thanks in large part to the contributions of David Freese.
Over the past 30 days, in his 21 games played, he has posted a .435/.547/.623/1.170 batting line.
He has racked up 30 hits, seven being doubles, two being home runs, and he drove in 11 RBI while scoring 14 of his own.
Milwaukee has been kind to Aramis Ramirez, and in turn he's been a solid player for the Brewers.
Over the past 30 days, Ramirez has played in 25 games, posting a .373/.393/.618/1.010 batting line.
He has managed 38 hits, 17 of which were for extra base hits. That breaks down to 13 doubles (leading the league over the last 30 days) with four home runs.
Additionally, Ramirez has driven in 22 RBI while scoring 15 of his own.
Finally, Albert Pujols is looking like Albert Pujols once again.
Over the past 30 days he's played in 24 games, posting a .323/.394/.720/1.115 batting line for the Angels.
In this time he has also posted 30 hits, 17 of which for extra bases. Broken down, that equates to 10 home runs and seven doubles.
In addition to finding his stroke, he has driven in 23 RBI, adding 18 runs of his own.
As you've figured out, he is the third of four players tied with 10 home runs over the past 30 days.
Low-risk with a high-reward.
That is exactly the type of player that Ryan Ludwick has been for the Cincinnati Reds this season, especially in the absence of Joey Votto.
Through the past 30 days, he has played in 22 games, posting a .333/.383/.747/1.129 batting line.
In addition, Ludwick has compiled 25 hits, and scattered throughout are five doubles, a triple and eight home runs.
He has driven in 23 RBI adding 12 runs of his own.
Like Albert Pujols with the Angels, Ryan Zimmerman started the 2012 season rather slow for the Washington Nationals.
That's certainly changed, specifically over the last 30 days. Zimmerman has posted a .361/.431/.722/1.153 batting line.
He has racked up 35 hits, 17 for extra bases. That equates to eight doubles and nine home runs for the All-Star third baseman.
He has driven in 20 RBI while scoring 24 runs of his own.
Though he owns the best OPS and has the most hits in baseball over the last 30 days, there are several other factors that went into this ranking system that brought 'Cutch to No. 3.
Don't get me wrong, I love what he's doing this season. His .433/.510/.733/1.243 batting line is certainly eye-popping.
He has played in 25 games and racked up 39 hits for the Bucs, breaking down to four doubles, a triple and seven home runs.
He has driven in 14 RBI while scoring 22 runs of his own.
Starting this process, I thought there was a good chance that Matt Holliday would have taken the No. 1 slot. He's been phenomenal for the St. Louis Cardinals.
In the past 30 days he has played in 24 games for the Cards, during which time Holliday has posted a .371/.456/.719/1.175 batting line.
Over the course of those 24 games, Holliday has racked up 33 hits, 15 of which were for extra bases in the form of seven doubles and eight home runs.
He has driven in 24 RBI and scored 17 runs of his own.
There's no surprise here, is there?
The kid has been incredible this season for the Angels and is on his way to owning the single greatest season any rookie has ever put together.
He owns a .371/.442/.742/1.185 batting line in 24 games over the last 30 days.
Trout has compiled 36 hits, 16 of which have been for extra bases. Broken down, that means five doubles, two triples and nine home runs.
He has driven in 22 RBI while adding 30 runs of his own.


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I'd like to thank everyone who voted down this comment. Because of your vigilance, my eye was instantly drawn to it and it turned out to be the only comment I really read. It didn't surprise me to find it was interesting and insightful as it actually dared to confront the cold, hard truth: WoW is a ridiculously easy game and articles like this make you guys look pathetic.
But don't lose heart, brave WoW.com warriors, I'm sure there will be another girl-meets-mace article in the near future that will cheer you up.


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King of the MixersThis review is from: KitchenAid KP26M1XNP Professional 600 Series 6-Quart Stand Mixer Nickel Pearl Pros: I bought the KitchenAid KP26M1XNP Stand Mixer as a Christmas gift for my wife. She's a baking and cooking fool. She is also a bit hard on things. For this reason I wanted to get a mixer that would hopefully be the last one we ever purchased. 3 years and thousands of baked goods later the mixer is working like it just came out of the box. This is a tank and worth the money. Plus the range of accessories make it useful for more than cookies. Cons: None. 1 out of 1 people found this review helpful. Did you? |
Unbelievably Good MixerThis review is from: KitchenAid KP26M1XPM Professional 600 Series 6-Quart Stand Mixer Pearl Metallic Pros: This mixer is powerful, the speed control is very precise, ingredients mix very, very well. There is a whole army of attachments available to help make short work of any food preparation chore. The 6 quart capacity is especially nice. Cons: The mixer is large and heavy. Do not purchase this if you do not plan on leaving it out on the counter. It is not really made to be put away between uses. Also, although it is not a problem for me, the mixer is quite tall. Make sure it will fit in your under your wall cabinets before you purchase it. Other Thoughts: You cannot go wrong with this mixer. This replaces a Sunbeam Mixmaster which is a toy compared to this Kitchenaid. 1 out of 1 people found this review helpful. Did you? |


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Dosher Memorial HospitalFederal loan to help Dosher modernizeSubmitted by Sarah Murphy on Mon, 08/12/2013 - 3:55pm.READ MORE:
Dosher Memorial Hospital has been working for this day for several years. Monday the hospital celebrated an $8.5 million, low-interest loan from USDA Rural Development. The facility will use the money to renovate all 25 rooms.
Full story... » ONLY ON 3: Mom says misdiagnosis led to son's deathSubmitted by Jayne Dees on Mon, 06/03/2013 - 5:49pm.READ MORE:
A woman is looking for answers after she says her son died because of mistakes made while treating him. A Dosher Memorial Hospital report says Mark Stephens had no history of diabetes although his mother has records that she he was treated at the hospital multiple times for the disease.
Full story... » Area hospitals get report card; Some grades good - many "average"Submitted by Scott Pickey on Mon, 12/13/2010 - 5:12pm.READ MORE:
A recent study done by a healthcare information service company points to some strong points and apparent deficiencies in the quality of care offered by area hospitals - reports the Greater Wilmington Business Journal.
Full story... » STATE PORT PILOT: Dosher asked to pay $1 million power billSubmitted by WWAY on Thu, 12/09/2010 - 10:05am.READ MORE:
The City of Southport is seeking more than $1 million from Dosher Memorial Hospital for electricity used but not paid for since fiscal year 2004, due to an error in billing discovered from internal audits of the city's utility accounts, the State Port Pilot reports.
Full story... » Dosher sponsors drug disposal eventSubmitted by WWAY on Mon, 08/09/2010 - 2:17pm.READ MORE:
Throwing medications down the drain or the toilet can pollute the water supply. And with prescriptions now the drug of choice for many teens, leaving old meds at home can be a bad idea.
Full story... » |
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Definición de languish en inglés:
Saltos de línea: lan|guishPronunciación: /ˈlaŋgwɪʃ
- 1(Of a person, animal, or plant) lose or lack vitality; grow weak: plants may appear to be languishing simply because they are dormantMás ejemplos en oraciones
- If your pet dog would truly languish in the wild, as a stray, you might be able to meet the comparable-life condition without meeting, say, his needs for adequate stimulation, exercise, and contact with other dogs.
- Aside from all this, a linden tree languishes at the inside corner of the last dogleg, just at the turn of the river, blocking the direct route to the green.
- Once again - many of those plants may simply languish in your garden's growing conditions.
weaken, grow weak, deteriorate, decline, go into a decline; wither, droop, flag, wilt, fade, fail, waste away• informal go downhill - 1.1Fail to make progress or be successful: Kelso languish near the bottom of the Scottish First Division (as adjective languishing) the country's languishing stock marketMás ejemplos en oraciones
- Saturday's home defeat to a side which was bottom of the Conference was the final straw, following a start to the season that has seen City languishing near the bottom of the table claiming just 16 points from 16 games.
- At the back however - even against an impoverished Hearts' display - there was no shortage of evidence as to why Killie are languishing near the bottom of the table.
- Although the team are languishing near the bottom of the third division, I am still very proud to be a York fan, and the other week when we beat Reading in the Cup I was so happy I had tears in my eyes.
- 1.2 • archaic Pine with love or grief: she still languished after RichardMás ejemplos en oraciones
- I have seen children all over the world languishing for love, and care, and giving.
- 2Be forced to remain in an unpleasant place or situation: he has been languishing in jail since 1974Más ejemplos en oraciones
- According to official figures, around 250,000 old appliances will be languishing in storage by the end of the year because of an EU directive demanding the safe disposal of the harmful chemicals they contain.
- They were eager to unearth every scrap of information, many having high hopes that they were related to someone rich and famous with an unclaimed fortune languishing in a long-forgotten bank account just begging to be collected.
- Supporters of democracy must firmly challenge that dangerous illusion and remind the world of the dissidents languishing in Cuban jails, many of whom have become seriously ill after being confined for long periods in dank cells.
waste away, rot, decay, wither away, moulder, be abandoned, be neglected, be forgotten, suffer; be disregarded, experience hardship
( • archaic ) - Más ejemplos en oraciones
- The whole mess, laced with pleas to 'Keep freakin' / Keep on freakin' out,' amounts to a suffocating Wall of displaced apathetic aggression and slacker languishment.
- No clue is offered to the identity of 'his […] favorite Disciple' other than Frasi but she was perhaps an amateur, one of those Fine Ladies whose hearts were caught by Saint-Germain's 'languishment'.
Middle English (in the sense 'become faint, feeble, or ill'): from Old French languiss-, lengthened stem of languir 'languish', from a variant of Latin languere, related to laxus 'loose, lax'.
Más definiciones de languish
Definición de languish en:- el diccionario Inglés de EE.UU.
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Manteca Police Chief Dave Bricker isn't dancing around the issue – he wants Club Leon's dance hall permit denied.
Eight cars were reported stolen late Tuesday and into Wednesday morning – one that was being warmed up while the owner went back into the residence to get a cup of coffee, police said.
One of the 12 defendants charged with conspiracy and other crimes in the federal racketeering case involving the Road Dog Cycle shop, has pleaded guilty.
A 19-year-old driver was shot while driving south on the East Highway 99 Frontage Road early Saturday morning north of Lathrop Road.
LATHROP – The Lathrop-Manteca Fire District fire marshal who was arrested last week on several drug-related charges while on duty and while driving a fire district utility vehicle has resigned.
LATHROP – A 15-year-old student at Lathrop High School was arrested Monday on campus by Sheriff's deputies on charges of possession of a controlled substance, suspected to be the drug ecstasy. The student, who was not identified because he is a minor, was released on a citation to his parents.
Lathrop-Manteca Fire Department inspector Jeffrey Scialabba, 29, was arrested while on duty Tuesday morning while driving a fire department utility vehicle and charged with possession of a small amount of methamphetamine, transportation of methamphetamine and possession of drug paraphernalia.
Jeremiah James Behrbaum, 19, ended a self-described all night birthday celebration with a police pursuit – finally being tackled by Manteca Police detective sergeant Tony Souza on his way to work Tuesday morning.
An alert and patient Manteca Police patrolman's efforts yielded an auto theft suspect and three "slim jims" used to open car doors Tuesday morning.
A man was shot in the leg during a fight Thursday in the 500 block of Morgan Court off Garden Gate in north Central Manteca.
A gay remark - taken as an insult - set a chain of events in motion that brought the arrest of John Herman McFarland, 18, and sent a Sierra High School junior to county hospital.
STOCKTON – If accused rapist Sid Reams were to get the heart valve replacement his court-appointed public defender says he needs to save his life, it'll likely be paid for by taxpayers.
A Manteca woman who told police earlier this month that she needed money to pay her $2,500 rent and an assortment of other bills including her PG&E was arrested again for grand theft and the unauthorized use of a credit card.
Felony crimes dropped almost 11 percent in Manteca during March.
First there was a call to police shortly after 7 p.m. Tuesday night about a verbal confrontation between two rival gangs in front of the Boys and Girls Club – and then a second call of shots fired in the same area where children were participating in activities inside the building.
Some 2,000 marijuana plants were confiscated from three different locations in Lathrop Friday morning leading to the arrest of two men.
If January is a precursor for how 2014 with turn out then major crime will drop significantly in Manteca.
It was a busy morning at Aki's Food To-Go and Grocery in Manteca. It was the crunch before the lunch hour, and owner Elda Paneda was busy attending to the customer traffic at the front counter.
A Manteca man was arrested early Thursday morning for attempted murder after allegedly trying to kill his father while he was sleeping.
Three men were taken into custody late Saturday in Modesto after leading multiple law enforcement agencies in a high-speed chase through two counties that started right next to Applebee's in Manteca.
A burglary attempt on the west side of Veritas School in the early hours Friday morning prompted a 911 call to Manteca Police.
LATHROP – The skeletal remains found by a bicyclist along Manthey Road last year have been determined to be those of a former trucking school student who has been missing since October of 2011.
A 23-year-old Manteca man surrendered himself Wednesday afternoon after allegedly taking his 24-year-old girlfriend and her 4-year-old daughter from their apartment against their will.
A hand gun replica that looked too much like the real thing led to Manteca Police handcuffing a 24-year-old man on South Main Street shortly before noon on Tuesday.
Postal officials are warning residents to keep an eye out after a rash of recent mailbox break-ins across the Central Valley.
Three men in their 20s attempting a home burglary shortly before 10 a.m. today (Tuesday) were arrested thanks to the quick action of a 13-year-old boy who was home because of his school's in-service day.
The designation of the vandalism against the Manteca Islamic Center as a "hate crime" can bring severe penalties for whoever is responsible.
The nation's largest Muslim civil rights organization is now calling on state and federal law enforcement agencies to aid in the investigation of what they're calling a "possible hate crime" at a Manteca prayer center.
Not even criminals are able to stay away from social media.
MODESTO (AP) - State and federal authorities took down a large drug-trafficking operation in the Northern San JoaquinValley with links to Mexico, arresting 11 people and seizing drugs and weapons, officials said.


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US 5550055 A Abstract A cDNA sequence encoding human T11 or a fragment thereof which is capable of inhibiting T-lymphocyte activation.
Claims(10) 1. An isolated nucleic acid having the nucleotide sequence set forth in FIG. 2 encoding the human T11 protein.
2. A vector comprising the DNA sequence set forth in FIG. 2 encoding the human T11 protein.
3. A cell transformed with a vector comprising the DNA sequence set forth in FIG. 2 encoding the human T11 protein.
4. A cell transformed with a vector comprising the DNA sequence set forth in FIG. 2 encoding the human T11 protein, wherein said cell is capable of expressing said human T11 protein.
5. An isolated nucleic acid having a nucleotide sequence encoding truncated human T11 protein, wherein the sequence encoding the transmembrane anchor region and cytoplasmic domain are deleted, said nucleotide sequence having the sequence of nucleotides which encode a polypeptide having the amino acid sequence of amino acids -24 through 185 as shown in FIG. 2.
6. A vector containing the isolated nucleic acid having a nucleotide sequence encoding truncated human T11 protein, wherein the sequence encoding the transmembrane anchor region and cytoplasmic domain are deleted, said nucleotide sequence having the sequence of nucleotides which encode a polypeptide having the amino acid sequence of amino acids -24 through 185 as shown in FIG. 2.
7. The nucleic acid of claim 5, wherein said nucleic acid is DNA or cDNA.
8. The nucleic acid of claim 5 having a nucleotide sequence which encodes a polypeptide having the amino acid sequence of amino acids -24 through 178 as shown in FIG. 2.
9. A cell containing the vector of claim 6.
10. A cell containing the vector of claim 6, wherein said cell is capable of secreting a truncated human T11 protein.
Description 4 lysed for one hour at 4 containing 0.15M NaCl, 1% vol/vol Triton-X 100, 1 mM iodoacetamide and the following protease inhibitors (Sigma): phenylmethylsulfonylfluoride (1 mM), chymostatin (0.5 μg/ml), pepstatin (0.5 μg/ml), antipain (0.5 μg/ml), leupeptin (0.5 μg/ml), trypsin inhibitor (0.02 μg/ml). The crude lysate was centrifuged at 3000 supernatant was made 0.5% in sodium deoxycholate and ultra-centrifuged for 60 min at 150,000 culture were surface radiolabelled by lactoperoxidase-catalyzed iodination. 2 of lysis buffer and added to the large scale lysate. The combined lysates were applied at 0.75 ml/min to a 15 ml "pre-clear" column containing irrelevant mouse monoclonal antibodies anti-T3 (8C8), anti-Ti.sub.3 (9H5) and anti-β2 microglobulin coupled to protein A Sepharose beads CL-4B (Pharmacia) at 5 mg antibody per ml of beads, followed by a 5 ml specific antibody column containing anti-T11.sub.1 (8B5) coupled to protein A Sepharose at 5 mg/ml. The anti-T11 column was washed with 10 mM Tris, pH 8.0 with or without detergents and eluted in 1 ml fractions with 0.1M glycine, pH 3.0, 0.5% Triton-X 100. The fractions were collected in tubes containing 60 μl 1M Tris pH 8 Fractions containing radioactivity were pooled, made 10% in glycerol and 2% in sodium dodecyl sulfate (SDS), heated at 60 loaded onto a 10% preparative polyacrylamide gel in a single lane 10 cm wide, and electrophoresed for 16 h at 40 volts. A 0.5 cm wide strip of the gel was dried and autoradiographed and the rest stained with Coomassie blue. Stained bands containing T11 were localized by comparison with the migration of surface labelled T11 as shown by the autoradiographed strip. Three regions of the gel at approximately 55, 53 and 50 kDa were excised. Gel slices were washed with H.sub.2 O and electroeluted in 50 mM ammonium bicarbonate containing 0.1% SDS for 16 h at 50 volts (Hunkapiller et al. Methods Enzymol, 91:227-236, 1983). Sample eluates were collected and proteins precipitated at -20 volumes of cold ethanol. Precipitated proteins were collected by centrifugation and the protein pellets vacuum dried. The ethanol precipitates were resuspended in 0.1% SDS and proteins were sequenced by Edman degradation on a gas phase protein sequenator (Applied Biosystems, model 120A) using the 03RPTH program and aqueous trifluoroacetic acid conversion chemistry. The PTH amino acids were identified with an on-line. PTH analyzer (Applied Biosystems, model 120A) using a narrow-bore C.sub.18 reverse phase column run in acetate buffered 5% aqueous tetrahydrofuran and developed with acetonitrile. 5-10 μg from the 55, 53 and 50 kDa bands were analyzed and an identical N-terminal sequence was obtained for each. Eighteen of the 19 N-terminal positions were assigned as follows: ##STR1## Isolation of cDNA Clones A cDNA library was constructed as follows. RNA was isolated from the T4 helper clone 5B by the method of Chirgwin et al. (1979). Polyadenylated RNA was isolated by oligo(dT)-cellulose chromatography (Pharmacia PL type 7). cDNA was cloned into the expression vector pCDVI (Okayama & Berg, Mol. Cell. Biol. 3:280-289 1983). The vector was purchased from Pharmacia and the library constructed according to the manufacturer's protocol. The 5B library was plated at 5-7 diameter plate. Replicas were made onto GeneScreen Plus (NEN), amplified with chloramphenicol at 150 μg/ml, denatured, neutralized, washed, dried, and hybridized with redundant oligonucleotide probes. The above amino acid sequence information was used to design these anti-sense oligonucleotide probes: ##STR2## Since a fully redundant set of 20 mers matching the first seven amino acids would contain 792 different sequences, we synthesized four independent pools, each containing a redundancy of 196. A 48 redundant 14 mer corresponding to the N-terminal residues 14-18 was also synthesized. Probes were synthesized using cyanoethyl phosphoramidites on an Applied Biosystems model 381A DNA synthesizer. After cleavage from the controlled pore glass column with NH.sub.4 OH, they were purified by passage over Sep-Pak C.sub.18 column (Millipore) and electrophoresis in 20% polyacrylamide gels. Purified redundant oligonucleotide probes were end-labelled with T4 polynucleotide kinase (Bethesda Research Labs) using 200 μCi α[.sup.32 P]-ATP (Amersham) for 0.2 μg of oligonucleotide. Amplified filters were hybridized with 192 redundant 20 mers at 40 C. in plaque screen buffer (50 mM Tris, pH 7.5, 1M NaCl, 1% SDS, 0.1% sodium pyrophosphate, 0.2% BSA, 0.2% Ficoll 400, 0.2% polyvinyl pyrrolidone for 16 h and washed at 43 mM Tris pH 7.5, 1M NaCl, 1% SDS, 0.2% sodium pyrophosphate) for 30 min. Colonies positive in the first round of screening were picked, replica plated, and rescreened with the 20 mer. Identical replicas were also hybridized with the 48-redundant 14 mer at 28 31 of 20 mers with a redundancy of 196 which hybridized in Northern analysis to T cell specific mRNAs identified 32 clones. These were isolated and rescreened with the 14 mer. Seventeen of 32 clones contained sequences complementary to both probes. BamHI digests of plasmid DNA from these clones revealed that 11 contained 1.6 kb inserts, three contained 1.3 kb inserts, and that three clones had lost a BamHI restriction site. A representative 1.6 kb insert from a clone termed PB1 and a representative 1.3 kb insert from a clone termed PB2 were subcloned into the M13 vector mp18 (New England Biolabs) for sequencing by the dideoxy chain termination method. Primers were either the universal primers supplied by the manufacturer or 17 mers synthesized on an Applied Biosystems model 381A. 10 g of 5B RNA and poly(A).sup.+ RNA from many cell types were electrophoresed under denaturing conditions in 7% formaldehyde and 0.02M NaPO.sub.4, pH 7 The RNA was transferred to nitrocellulose and hybridized to .sup.32 P-labeled PB1 DNA in 50% formamide, 5 Denhardt's, 5 12 h at 42 filter was washed in 2 and in 0.1% SSC, 0.1% SDS at 50 for 48 h with an intensifying screen. In these experiments, PB1 DNA was labelled by random priming as described (Feinberg et al. Anal. Biochem. 132:6-13, 1983). DNA from T cell line REX was restriction digested and electrophoresed in a 0.8% agarose gel. The gel was denatured, neutralized and transferred to nitrocellulose using 10 were as for northern analysis. Referring to FIG. 1, the 1.6 kb insert of PB1 (solid line) was separated from the plasmid by BamHI digestion and subcloned into the M13 sequencing vector mp18. The M13 universal primer was used to derive initial sequence at the 5' end. Subsequently, primers of 17 nucleotides were used for dideoxy sequencing. Sequencing reactions were also performed on M13 clones which contained BamHI-SacI and SacI-BamHI fragments as shown. The open reading frame of the insert is identified by the thick solid bar. Referring to FIG. 2, there is shown the cDNA and predicted protein sequence of PB1. The probable signal peptide (----), the NH.sub.2 -terminus of the mature protein () and the position of a CNBr cleavage derived fragment () are shown. Polyadenylation signals at nucleotides 1103 and 1505 are underlined. The last nucleotide before the poly(A) tail in clone PB2 is indicated by an arrowhead at position 1125. The complete nucleotide sequence of clone PB1 is 1,525 bases in length and flanked by a poly(A) sequence at its 3' end. An open reading frame of 1,080 bases (positions 24-1103) begins with an ATG methionine codon and is flanked by 23 nucleotides of 5' untranslated sequence and by 419 bases of 3' untranslated sequence. A polyadenylation signal (AATAAA) is located 18 bases upstream from the beginning of the poly(A) tail (FIG. 2). PB2 is identical to PB1 except that it lacks four nucleotides present at the 5' end of PB1 and has a shorter 3' untranslated region. A poly(A) tail was noted in PB2 after the nucleotide corresponding to residue 1125 in PB1 (arrow head). The bases from positions 1102 to 1103 form part of a G1n codon at amino acid 336 and a stop codon as well as the first five bases of the polyadenylation signal AATAAA (nucleotides 1102-1106) for mRNA corresponding to clone PB2. The N-terminal lysine of the mature polypeptide is preceded by a sequence coding for a stretch of 24 hydrophobic amino acids which likely represents the signal sequence required for the T11 precursor to be transported across the endoplasmic reticulum. The cDNA sequence predicts three potential N-linked glycosylation sites (Asn-X-Ser/Thr) on the mature protein at amino acid positions 65, 117 and 126. An extremely hydrophobic stretch of 25 amino acids characteristic in size and composition of a transmembrane domain is found at positions 186-210. This region is followed by seven basic amino acids within the next ten residues consistent with the notion that this is the start of the intracytoplasmic domain. 21% of residues in the region of amino acids 211-336 are prolines. This cDNA sequence predicts a molecular weight for the mature polypeptide backbone of 37,994 daltons. To determine the molecular weight of the broad 50-55 kDa band in the absence of N-linked sugars, surface labelled T11 was digested with endoglycosidase F and analyzed by SDS-PAGE. After digestion with endoF, there is a loss of the 55 kDa band and the appearance of a major component at approximately 40 kDa. These data suggest that the 55 kDa protein exists as a 40 kDa structure in the absence of any N-linked sugar moieties and is consistent with the above determined molecular weight of the protein. These results are consistent with the possibility that all three N-linked glycosylation sites may be utilized. Two related T11 mRNA species Northern analysis using poly(A).sup.+ RNA or cytoplasmic RNA from a variety of sources indicates that expression of the PB1 and PB2 sequences is T lineage specific and yields two common bands of 1.7 and 1.3 kb. Thus, each of six human T lineage cells tested including activated T helper clones, thymus derived tumors, normal thymocytes, activated T cells, and resting peripheral blood T lymphocytes expresses the 1.7 and 1.3 kb transcripts. In contrast, non-T lineage cells such as normal peripheral blood B cells and macrophages, an Epstein-Barr Virus-transformed B lymphoblastoid line, Laz 509, and the non-lymphoid hematopoietic cell lines HL-60 and U937 lack both transcripts. Given the similarity in size differences between the PB1 and PB2 inserts (400 bases) and the two species of mRNA, it is likely that PB1 and PB2 cDNAs correspond to the 1.7 kb and 1.3 kb transcripts, respectively. This is further supported by the finding that an oligonucleotide based on a sequence from the 3' untranslated region unique to PB1 selectively hybridizes in northern analysis to sequences in the 1.7 kb site region. Considerable variability exists within the level of expression of the 1.7 and 1.3 kb transcripts among individual T lineage tumor cells and physiologic T cell populations. Also, activated T cells express >10 fold higher amounts than resting T lymphocytes. This result is consistent with data indicating that T11 surface expression increases from 20,000 to 200,000 copies per cell upon activation with mitogens or antigens during a six day period and suggests that this differential expression is at least in part transcriptionally regulated. PB1 homologous sequences are also expressed in murine thymocytes. However, under the conditions of hybridization, only the 1.3 kb molecular weight species is detected in poly(A).sup.+ mRNA from BAlB/cJ thymocytes. It is thus likely that the murine species lacks the second polyadenylation signal in the 3' untranslated region of a homologous gene. This result also suggests that a highly homologous T11-related structure exists on murine T lineage cells. The T11 molecule is encoded by a single copy gene To determine the number of T11 genes present in the human genome, southern analysis was performed with the .sup.32 P-labeled PB1 insert. The probe hybridizes to a set of bands of approximately 8 and 7 kb in a BamHI digest of genomic DNA form T cell REX, to a single band >14 kb in EcoRI restricted REX DNA, and to a set of 7.4, 6.0 and 0.7 kb fragments in Hind III digested REX DNA. Analysis of DNA from granuloctyes gave an identical pattern, indicating that T11 is in the human genome as a single copy gene and, unlike the T cell receptor alpha, beta and gamma genes or the B cell IgH and light chain genes, does not rearrange in lymphoid cells. PB1 and PB2 cDNAs encode a functional T11 protein To further prove that the sequences contained in the PB1 and PB2 cDNA clones encode the T11 protein and are themselves necessary and sufficient for T11 surface expression, COS-1 cells were transfected with PB1 or PB2 plasmid cDNAs or the unrelated IL-3 cDNA. COS-1 cells were plated at 4 fetal calf serum, 0.03% glutamine, 1% penicillin-streptomycin. Six ug of μg PB2 or IL-3 (a gift of Ken-ichi Arai, DNAX) plasmid DNA was added to 350 μl RPMI and vortexed. 350 μl of 800 μg/ml DEAE-Dextran in RPMI, 100 mM Tris, pH 7.4 was added to the plasmid solution and vortexed. This solution was added to one well of cells which were then incubated for 3 h in a 37 washed once with RPMI. Subsequently, 2.5 ml of RPMI containing 2% fetal calf serum, 0.03% glutamine, 1% penicillin streptomycin, 150 μM chloroquine was added to each well and the cells incubated at 37 C. for 3 h. The cells were washed twice with RPMI and after addition of fresh medium, incubated for 48 h at 33 assay for surface T11 expression. Ten thousand cells in each transfection group were analyzed by fluorescence activated cell sorting. After 48-72 h, expression of surface T11 on the transfected cell was determined on the basis of anti-T11 monoclonal antibody reactivity measured by indirect immunofluorescence on an Epics V cell sorter and by rosette formation with sheep erythrocytes. The non-transfected COS-1 cells failed to interact with anti-T11.sub.1 antibody. In contrast, after transfection with PB2, >25% of COS-1 cells express readily detectable surface T11 molecules. An identical level of reactivity was also detected with an anti-T11.sub.2 monoclonal antibody. Similar levels of anti-T11.sub.1 and anti-T11.sub.2 reactivity resulted from transfections using PB1. To next determine whether the transfected and expressed PB1 and PB2 sequences could themselves endow COS-1 cells with the ability to form aggregates with SRBC, transfected cells were tested for SRBC binding capacity. Incubation of SRBC with COS-1 cells resulted in no rosette formation. In contrast, after transfection of COS-1 cells with PB2, SRBC rosetting was observed. The SRBC rosette forming capacity was detected in COS-1 cells transfected with either of the two PB cDNAs separately or together. While the SRBC rosette capacity was not inhibited by monoclonal antibodies directed against the T3 subunits of the T3-Ti antigen/MHC receptor complex, the anti-T11.sub.1 monoclonal antibody completely abrogated E rosette formation. Collectively, the above data provide unequivocal proof that the PB1 and PB2 cDNA sequences each independently encode a functional T11 protein. Functional Domains of T11 Referring to FIG. 3, the T11 molecule has a hydrophobic signal peptide (L), which is cleaved upon biosynthesis. The hydrophilic, 185 amino acid long external domain of the molecule is located outside the cell membrane. The hydrophobic 25 amino acid long transmembrane (TM) anchor region is embedded in the T-cell membrane, and the 126 amino acid long cytoplasmic domain of the molecule remains in the cytosol. In FIG. 3, the proline-rich region of this domain is indicated by P-P-P. The amino acid numbering corresponds to the mature peptide. Cells transfected with PB1, like T-cells which naturally produce T11, do not secrete T11, but rather retain the T11 molecule by means of the transmembrane anchor, with only the external domain exposed. A truncated T11 molecule, with the transmembrane and cytoplasmic domains deleted, can, unlike the complete T11 molecule, be secreted by transfected cells and used in the applications described below. Such a truncated molecule can be prepared in a manner analogous to the method by which an anchor-minus IL-2 receptor molecule was prepared by Treiger et al. (1986) J. Immunol. 136., 4099. The truncated IL-2 receptor was found to be capable of binding to its ligand, IL-2. To make the truncated T11 molecule, PB1 or PB2 cDNA representing the gene for the entire T11 molecule will be restricted with PvuII. This enzyme uniquely cuts within the 1,525 base pair T11 molecule cDNA insert between bases 628 and 629, resulting in removal of all transmembrane and intracytoplasmic sequences and seven amino acids of the external domain. Subsequently, a 14 base phosphorylated synthetic oligonucleotide (CTAAGAATTCTTAG) containing the third base of the codon for amino acid 178, a termination codon TAA followed by the six base recognition sequence for. EcoRI (GAATTC), and four nucleotides (TTAG) complementary to CTAA, will be ligated to the PvuII restricted plasmid DNA with T4 DNA ligase. The DNA will then be digested with PstI to separate the 5' end of the cDNA insert from the plasmid DNA and then subcloned into an appropriate expression vector. For example, this fragment could be blunted by T4 DNA polymerase to remove the PstI site and then be ligated to the EcoRI linker by T4 ligase. Finally, it could be digested with EcoRI before ligation into the unique EcoRI site of the publicly available pcEXV-1 expression vector. Use of T11 The T11 protein, or its truncated, secreted form, can be used in a variety of diagnostic and therapeutic applications, all of which are based on the binding of T11 to its natural ligand on human lymphocytes and homologous surface structures present on target cells which facilitate T lymphocyte--target cell interactions, which result in target cell lysis or lymphocyte proliferation. (Siliciano et al. Nature 317:428-431 (1985); and Palacios and Martinez-Maza, J. Immunol. 129:2479-2485 (1982)). The T11 molecule is expressed on the surface of many human T-cell malignancies, e.g., T-cell leukemias and lymphomas. In addition, autoimmune diseases, e.g., rheumatoid arthritis and systemic lupus erythmatosis (SLE), are characterized by the presence in the blood and lymph of large numbers of T11-bearing T-cells. Rapid cell turnover in these disease states can cause the shedding of the T11 molecule into the bloodstream. T11 can be used as an immunogen to produce polyclonal or monoclonal anti-T11 antibodies, using conventional techniques. These antibodies can be labeled with any conventional label, e.g., radioisotopes, and used in conventional immunoassay methods to measure serum T11 levels and thus monitor patients having T-cell-associated diseases. Particularly sensitive ELISA-type assays will employ two anti-T11 antibodies, each to a different antigenic determinant on the surface of T11, in a sandwich format. Another use for the anti-T11 antibodies is in the purification of recombinant T11, produced as described above. The anti-T11 is coupled to a column and T11-containing media is passed through the column so that the T11 reversibly binds to the T11, after which anti-T11 antibodies is eluted in purified form, according to conventional methods. The disease states which can be treated using T11 include medical conditions characterized by unwanted activity of the immune system which results in excess T-cell activation, which plays a key role in the amplification of the immune response. These conditions include rheumatoid arthritis; Systemic Lupus Erythmatosis; juvenile onset diabetes; multiple sclerosis; allergic conditions; inflammatory conditions such as eczema, ulcerative colitis, inflammatory bowel disease, and Crohn's disease; and allograft rejection (e.g., rejection of a transplanted heart or kidney). Soluble T11 competes with the surface-bound T11 for its ligand on target cells thus dampening immune response amplification. The T11 admixed with a pharmaceutically acceptable carrier substance such as saline, is administered intravenously to a human patient in an effective amount, e.g., 20 μg to 500 μg per kg body weight. For some conditions, T11 can be administered directly to the site where needed most; for example, T11 can be injected directly into the inflamed joint of a human patient suffering from rhematoid arthritis. Plasmid PB1 was deposited on Oct. 1, 1986 in the American Type Culture Collection, Rockville, Md., and assigned ATCC Accession Number 40268. Applicants' assignee, Dana-Farber Cancer Institute, acknowledges its responsibility to supply a sufficient quantity of the plasmid DNA for the term of a patent issued hereon, 5 years after the last request for the plasmid, or 30 years from the date of deposit, whichever is the longer, and its responsibility to notify the depository of the issuance of such a patent, at which time the deposits will be made irrevocably available to the public. Until that time the deposit will be made available to the Commissioner of Patents under the terms of 37 C.F.R. Section 1-14 and 35 U.S.C. Section 112. Other embodiments are within the following claims. The drawings will first be described. Drawings FIG. 1 is a diagrammatic representation of the strategy used in sequencing the cDNA (PB1) encoding T11. FIG. 2 is the sequence of the PB1 cDNA, with the deduced amino acid sequence of T11 given on the bottom line. FIG. 3 is a diagrammatic representation of the T11 molecule showing functional domains. This invention relates to human T-lymphocytes ("T-cells"). The T11 sheep erythrocyte binding glycoprotein [relative molecular mass (M.sub.r) 50,000-55,000] is expressed throughout human T-lymphocyte ontogeny and appears to play an important physiological role in T-cell activation. The treatment of T cells with certain monoclonal anti-T11 antibodies results in antigen independent polyclonal T-cell activation as assessed by proliferation and lymphokine secretion. In addition, the majority of thymocytes that have not yet acquired the T3-Ti antigen/major histocompatibility complex (MHC) receptor can be activated to express interleukin-2 (IL-2) receptors through this T11 structure. Three distinct epitopes on the 50 K T11 molecule have been identified. While the T11.sub.1 and T11.sub.2 epitopes are expressed on resting as well as activated T cells, anti-T11.sub.3 antibodies recognize a spatially distinct epitope that is preferentially expressed on mitogen- or antigen-activated T lymphocytes and thymocytes. The T11.sub.3 epitope appears to represent a conformational change since it can be induced on resting T cells within 30 min at 4 anti-T11.sub.2. These studies have also shown that the combination of anti-T11.sub.2 and anti-T11.sub.3 (and to a lesser extent certain anti-T11.sub.1, anti-T11.sub.3 antibodies) can induce IL-1-independent polyclonal T-cell activation as measured by proliferation and lymphokine secretion. We have succeeded in producing a cDNA sequence encoding the human T11 molecule. In addition, we have completely sequenced the T11 cDNA, and thus know the deduced amino acid sequence of the T11 protein. We have inserted the T11 cDNA into an expression vector, which was used to transfect mammalian cells, which have been shown to express immunologically functional T11. The deduced amino acid sequence of T11 has allowed us to identify the functional domains of the T11 molecule, which include the signal peptide, the external domain, the transmembrane anchor, and the internal cytoplasmic domain. Because it is the external domain which is recognized by and binds to the natural ligand of T11 found on human lymphocytes, truncated T11 can be produced by recombinant cells according to the invention, in which truncated T11 will be secreted by transfected cells for isolation and use in therapeutic applications which depend on the ability of the external domain of T11 to bind to its ligand, as will be explained in more detail below. The preferred genetic constructions thus are those encoding a human lymphocyte activation inhibiting fragment of T11, from which is deleted the transmembrane anchor and the cytoplasmic domain. Such fragments generally will bind to human lymphocytes and human red blood cells which express a homologous set of surface structures. A human lymphocyte inhibiting fragment is, as defined herein, a fragment which is capable of competing with the naturally-present T11 on the surface of a human lymphocyte, thus interfering with the ability of the lymphocyte to make contact with its target cells (if the lymphocyte is a cytolytic cell), or with macrophages having T11 binding structures which permit the cell-to-cell contact necessary for lymphocyte proliferation. To test a fragment for the ability to inhibit lymphocyte proliferation, or the cytotoxic effector function, the fragment is contacted with the lymphocytes prior to stimulation with mitogen, and the degree of proliferation is measured, using standard techniques, and the result is compared to a control in which the fragment was not used. Other features and advantages of the invention will be apparent from the following description of the preferred embodiments thereof, and from the claims. This application is a continuation of application U.S. Ser. No. 08/361,014 filed Dec. 21, 1994, which is a file wrapper continuation of U.S. Ser. No. 07/902,436 filed Jun. 18, 1992 (abandoned), which is a file wrapper continuation of U.S. Ser. No. 7/714,323 filed Jun. 11, 1991 (abandoned), which is a file wrapper continuation of U.S. Ser. No. 06/932,871, filed Nov. 18, 1986 (abandoned), which is a continuation-in-part of U.S. Ser. No. 06/913,988, filed Oct. 1, 1986 (abandoned), which is a continuation-in-part of U.S. Ser. No. 06/906,413, filed Sep. 11, 1986 (abandoned). All of the above applications are incorporated herein by reference in their entirety. The work described herein was made with the aid of government funding, and the government therefore has certain rights in the invention. Patent Citations
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Book Description:Blocky or small. Thick or tall.Roundish, slope-y, fancy or dopey.Letters look different in all different places.That's because they have different typefaces.From an alligator made of aaa's to a zebra made of zzz's, the alphabeasties in this book are ingeniously built out of multiple typefaces. Adults and children will be engaged and delighted with the flaps, which lift to reveal "beasties" for each letter of the alphabet.
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