text:
PREventing Progression of Adipose Tissue Redistribution
This study has been completed.
International Antiviral Therapy Evaluation Center
Gilead Sciences
Information provided by:
International Antiviral Therapy Evaluation Center
ClinicalTrials.gov Identifier:
First received: October 17, 2006
Last updated: June 10, 2010
Last verified: June 2010
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Show Detailed Description
The main objective of the study is to assess changes in fat distribution over 48 weeks of treatment in patients who currently successfully use zidovudine (AZT) and lamivudine (3TC) as part of their regimen and who will either continue these antiretrovirals or who will switch these antiretrovirals to tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC). Each of these medications is commonly used for the treatment of HIV-1 infection.
Condition | Intervention | Phase |
HIV Infections |
Drug: continuing AZT+3TC or switching AZT+3TC to TDF+ FTC |
Phase 4 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Prevention |
Official Title: | A Randomized, Controlled, Open-Label, 48-Week Study of Continuing Successfully Suppressive Treatment in HIV-1 Infected Adults With First-Line Twice-Daily Zidovudine and Lamivudine-Based Regimens Versus Pro-actively Replacing of Zidovudine and Lamivudine by Once-Daily Emtricitabine and Tenofovir Disoproxil Fumarate to Prevent Progression of or Reverse Peripheral Lipoatrophy. |
Resource links provided by NLM:
Further study details as provided by International Antiviral Therapy Evaluation Center:
Secondary Outcome Measures:
- Difference between the continuation arm and the switch arm in:
- changes in subcutaneous and visceral abdominal fat by CT and truncal fat by whole body DEXA over 48 weeks
- changes in lipids (total-, HDL-, and LDL-cholesterol, total /HDL cholesterol ratio, triglycerides), and glucose-metabolism (glucose, insulin) and insulin resistance (HOMA-index1) over 48 weeks.
- incidence of new onset of lipodystrophy and changes in lipodystrophy severity according to the LDCD score.
- changes in bone mineral density by regional DEXA (vertebra L4 and femoral neck) over 48 weeks
- proportion of patients with plasma HIV-1 RNA concentrations < 50 copies/mL after 48 weeks and proportion of patients that developed new CDC-C events or increased in CDC classification.
- incidence and severity of adverse events (grade 3 and 4), and laboratory abnormalities (grade 1-4)
- A comparison between different GFR-estimations and the gold standard for GFR-measurement in HIV-1 infected patients on HAART. [ Time Frame: baseline ] [ Designated as safety issue: No ]Conclusions: Each eGFR estimation underestimated the mGFR. In patients with preserved renal function and suppressed HIV-infection, C&G, 24-hours urine clearance and MDRD-6 based eGFR reasonably estimated true GFR, but cysC-based eGFR did not.
Estimated Enrollment: | 120 |
Study Start Date: | April 2006 |
Study Completion Date: | October 2008 |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Providing written informed consent
- HIV-1 infected patients.
- At least 18 years of age.
- Males or non-pregnant, non-lactating females. Women of childbearing age must have a negative urine pregnancy test at screening. All female participants must be encouraged to utilise adequate contraception for the month preceding entry and for the duration of the study.
- Treatment for at least two years with a first-line regimen of zidovudine plus lamivudine (as either a fixed dose combination or dosed separately) plus either an NNRTI or a (boosted) PI. Patients may have previously used multiple drugs from both the NNRTI or the PI classes.
- Plasma HIV-1 RNA levels < 50 copies/mL for at least 6 months at screening. Isolated measurements of plasma HIV-1 RNA levels above 50 but below 200 copies/ml (socalled blips) are allowed.
Exclusion Criteria:
- Prior treatment with an NRTI other than zidovudine or lamivudine.
- Use of a triple NRTI antiretroviral regimen or a regimen including unboosted saquinavir, fusion inhibitors or hydroxyurea
- Prior virological treatment failure, defined as having had to switch antiretroviral therapy because of virologic failure in the opinion of the physician.
- HIV-2 co-infection.
- Renal impairment and/or use of nephrotoxic agents which in the opinion of the investigator are a contraindication for the use of tenofovir disoproxil fumarate.
- Clinically relevant laboratory abnormalities: anemia, thrombocytopenia, leucopenia, elevated liver transaminases, elevated bilirubin, elevated amylase, elevated lipase.
- Use of co-medication, other than antiretroviral drugs, with a known pharmacological interaction with one or more of the study drugs
- Active alcohol or drug use, sufficient in the investigator's opinion to prevent compliance with the dosing schedule and evaluations (methadone and buprenorphine use is allowed, although the dose of methadone might need to be adjusted).
- Anticipated non-compliance with the protocol.
- Presence of a newly (within 30 days prior to the time of enrolment) diagnosed HIV-related opportunistic infection or condition which may interfere with the ability to comply with the study.
- Chronic active viral hepatitis or other chronic liver disease, which in the opinion of the investigator is a contraindication for the use of any of the study drugs.
- Women who have the intention to become pregnant during the study period.
- Patients who have received within 4 weeks prior to entry, or who have an anticipated need for treatment with radiation therapy or cytotoxic chemotherapeutic agents during the protocol study period.
- Patients who have taken any investigational drug 30 days prior to the start of the study
- Patients with malabsorption syndrome or other gastrointestinal dysfunction which may interfere with drug absorption or prevent the patient from taking oral medication.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00389194
Netherlands | |
Academic Medical Centre | |
Amsterdam, Netherlands |
Sponsors and Collaborators
International Antiviral Therapy Evaluation Center
Gilead Sciences
Study Chair: | Peter Reiss, MD, PhD | Academic Medical Centre |
More Information
No publications provided by International Antiviral Therapy Evaluation Center
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by International Antiviral Therapy Evaluation Center:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on March 13, 2014
No publications provided by International Antiviral Therapy Evaluation Center
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: | NCT00389194 History of Changes |
Other Study ID Numbers: | PR-0095_01, Eudract number: 2005-005672-33 |
Study First Received: | October 17, 2006 |
Last Updated: | June 10, 2010 |
Health Authority: | Netherlands: The Central Committee on Research Involving Human Subjects (CCMO) |
Keywords provided by International Antiviral Therapy Evaluation Center:
HIV-1 infection fat distribution lipodystrophy |
lipids kidney function Treatment Experienced |
Additional relevant MeSH terms:
HIV Infections Acquired Immunodeficiency Syndrome Lentivirus Infections Retroviridae Infections RNA Virus Infections Virus Diseases Sexually Transmitted Diseases, Viral Sexually Transmitted Diseases Immunologic Deficiency Syndromes Immune System Diseases Slow Virus Diseases Tenofovir disoproxil |
Tenofovir Lamivudine, zidovudine drug combination Reverse Transcriptase Inhibitors Nucleic Acid Synthesis Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Pharmacologic Actions Anti-Retroviral Agents Antiviral Agents Anti-Infective Agents Therapeutic Uses Anti-HIV Agents |
ClinicalTrials.gov processed this record on March 13, 2014


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commandlinefu.com is the place to record those command-line gems that you return to again and again.
Delete that bloated snippets file you've been using and share your personal repository with the world. That way others can gain from your CLI wisdom and you from theirs too. All commands can be commented on, discussed and voted up or down.
If you have a new feature suggestion or find a bug, please get in touch via http://commandlinefu.uservoice.com/
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Grabs the cmdline used to execute the process, and the environment that the process is being run under. This is much different than the 'env' command, which only lists the environment for the shell. This is very useful (to me at least) to debug various processes on my server. For example, this lets me see the environment that my apache, mysqld, bind, and other server processes have.
Here's a function I use:
aa_ps_all () { ( cd /proc && command ps -A -opid= | xargs -I'{}' sh -c 'test $PPID -ne {}&&test -r {}/cmdline&&echo -e "\n[{}]"&&tr -s "\000" " "<{}/cmdline&&echo&&tr -s "\000\033" "\nE"<{}/environ|sort&&cat {}/limits' ); }
From my .bash_profile at http://www.askapache.com/linux-unix/bash_profile-functions-advanced-shell.html
Gives the same results as the command by putnamhill using nine less characters.
1) -n-1 means sort key is the last field
2) -l is important if each separate record is on a new line (usually so for text files)
3) -j tells msort not to create log file (msort.log) in the working directory
4) may need to install msort package.
5) msort does lot more. Check man msort
Works in sort (GNU coreutils) 7.4, don't know when it was implemented but sometime the last 6 years.
Another one.
Maybe not the quicker because of the sort command, but it will also look in other man sections.
updated with goodevilgenius 'shuf' idea
All with only one pipe. Should be much faster as well (sort is slow). Use find instead of ls for recursion or reliability.
Edit: case insensitive
If your grep doesn't have an -o option, you can use sed instead.
Essentially the same as funky's alias, but will not traverse filesystems and has nicer formatting.
Use this BASH trick to create a variable containing the TAB character and pass it as the argument to sort, join, cut and other commands which don't understand the \t notation.
sort -t $'\t' ...
join -t $'\t' ...
cut -d $'\t' ...
Shows a list of users that currently running processes are executing as.
YMMV regarding ps and it's many variants. For example, you might need:
ps -axgu | cut -f1 -d' ' | sort -u
Most systems (at least my macbook) have system users defined, such as _www and using "users" for example will not list them. This command allows you to see who the 'virtual' users are on your system.
I love this function because it tells me everything I want to know about files, more than stat, more than ls. It's very useful and infinitely expandable.
find $PWD -maxdepth 1 -printf '%.5m %10M %#9u:%-9g %#5U:%-5G [%AD | %TD | %CD] [%Y] %p\n' | sort -rgbS 50%
00761 drwxrw---x askapache:askapache 777:666 [06/10/10 | 06/10/10 | 06/10/10] [d] /web/cg/tmp
The key is:
# -printf '%.5m %10M %#9u:%-9g %#5U:%-5G [%AD | %TD | %CD] [%Y] %p\n'
which believe it or not took me hundreds of tweaking before I was happy with the output.
You can easily use this within a function to do whatever you want.. This simple function works recursively if you call it with -r as an argument, and sorts by file permissions.
lsl(){ O="-maxdepth 1";sed -n '/-r/!Q1'<<<$@ &&O=;find $PWD $O -printf '%.5m %10M %#9u:%-9g %#5U:%-5G [%AD | %TD | %CD] [%Y] %p\n'|sort -rgbS 50%; }
Personally I'm using this function because:
lll () { local a KS="1 -r -g"; sed -n '/-sort=/!Q1' <<< $@ && KS=`sed 's/.*-sort=\(.*\)/\1/g'<<<$@`;
find $PWD -maxdepth 1 -printf '%.5m %10M %#9u:%-9g %#5U:%-5G [%AD | %TD | %CD] [%Y] %p\n'|sort -k$KS -bS 50%; }
# i can sort by user
lll -sort=3
# or sort by group reversed
lll -sort=4 -r
# and sort by modification time
lll -sort=6
If anyone wants to help me make this function handle multiple dirs/files like ls, go for it and I would appreciate it.. Something very minimal would be awesome.. maybe like:
for a; do lll $a; done
Note this uses the latest version of GNU find built from source, easy to build from gnu ftp tarball. Taken from my http://www.askapache.com/linux-unix/bash_profile-functions-advanced-shell.html
Once you get into advanced/optimized scripts, functions, or cli usage, you will use the sort command alot. The options are difficult to master/memorize however, and when you use sort commands as much as I do (some examples below), it's useful to have the help available with a simple alias. I love this alias as I never seem to remember all the options for sort, and I use sort like crazy (much better than uniq for example).
# Sorts by file permissions
find . -maxdepth 1 -printf '%.5m %10M %p\n' | sort -k1 -r -g -bS 20%
00761 drwxrw---x ./tmp
00755 drwxr-xr-x .
00701 drwx-----x ./askapache-m
00644 -rw-r--r-- ./.htaccess
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history 1000 | sed 's/^[0-9 ]*//' | sort -fubdS 50%
exec bash -lxv
export TERM=putty-256color
Taken from my http://www.askapache.com/linux-unix/bash_profile-functions-advanced-shell.html
Works with files containing spaces and for very large directories.
This provides a way to sort output based on the length of the line, so that shorter lines appear before longer lines. It's an addon to the sort that I've wanted for years, sometimes it's very useful. Taken from my http://www.askapache.com/linux-unix/bash_profile-functions-advanced-shell.html
I've wanted this for a long time, finally just sat down and came up with it. This shows you the sorted output of ps in a pretty format perfect for cron or startup scripts. You can sort by changing the k -vsz to k -pmem for example to sort by memory instead.
If you want a function, here's one from my http://www.askapache.com/linux-unix/bash_profile-functions-advanced-shell.html
aa_top_ps(){ local T N=${1:-10};T=${2:-vsz}; ps wwo pid,user,group,vsize:8,size:8,sz:6,rss:6,pmem:7,pcpu:7,time:7,wchan,sched=,stat,flags,comm,args k -${T} -A|sed -u "/^ *PID/d;${N}q"; }
Gives you a list for all installed chrome (chromium) extensions with URL to the page of the extension.
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The company just announced plans to drop prices on some of its products, so that more customers can enjoy Clark Synthesis sound. According to a company spokesperson, the following products will receive price reductions:
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bio | website | fivesecondreview.wordpress.co… |
location | Downtown Burbank | |
age | 40 | |
visits | member for | 2 years, 5 months |
seen | 17 hours ago | |
stats | profile views | 548 |
I'm a Community Manager for Stack Exchange. I've been known to respond to firstname.lastname@example.com
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These linear parks consist of approximately 1,200 acres of creek-side open space.
The Linear Creekway Parks Development Program, which provides sales tax funding for the land purchases and trails development, was approved by voters in 2000, 2005 and 2010. Thanks to the ongoing support of San Antonians, the current budget for trail development includes enough to build approximately 41 additional miles of trail (for a total of 86 miles).
Trails are now either built or planned for many of San Antonio's creeks, including the Salado, Leon, Huebner, Olmos, Huesta, Culebra, Alazan, Apache, Martinez, San Pedro and the Medina River.
Former Mayor Peak began formulating the idea of a "ring' of hike and bike trails in flood zones along city-owned creeks while working in the Planning Department and while serving on the Zoning Commission. As a City Councilman representing District 9 from 1993 to 1997, he partnered with Councilman Lyle Larson to purchase the land which began the Salado Creek trail system in Walker Ranch Historic Landmark Park.
As mayor from 1997 to 2001, he solidified his vision of hike and bike trails along Leon and Salado Creeks and won citizen support to dedicate one-eighth of a cent of the sales tax to begin development of the trail system in partnership with the Edwards Aquifer Program.
On the Horizon:
The ultimate vision to encircle the entire City of San Antonio with a complete ring of trails requires additional funding for approximately 32 miles of new trail, primarily along Leon and Salado Creeks. When the full system is completed, the connected network of trails along tributaries, neighborhood connections and the San Antonio River totals over 130 miles!
Project Maps
Route | Map |
Downtown Southtown Route | PDF 452kb |
River Walk Museum Reach | PDF 432kb |
Metro Health to Lexington | PDF 502kb |
Brackenridge Alamo Loop | PDF 463kb |
San Antonio Highlights Route | PDF 400kb |
All Run DT Routes | PDF 3.14mb |
Route | Map |
Alamo HemisFair | PDF 521kb |
Brackenridge | PDF 716kb |
Pearl Brewery | PDF 872kb |
King William | PDF 914kb |
Mission Trail | PDF 1mb |
East Side | PDF 342kb |
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The Parks and Recreation Department is pleased to announce that the Leon Creek Greenway North and the Medina River Greenway have been designated as national recreation trails, joining a network of more than 1,150 previously designated trails that span more than 13,650 miles through 23 states.
The department will receive a certificate of designation, a letter of congratulations from Secretary of the Interior Ken Salazar, and a set of trail markers.
The recent announcement made by Salazar and National Park Service Director Jonathan B. Jarvis included the designation of 54 trails as national recreation trails, adding almost 1,400 miles of trails to the National Trails System. The Tejano Walking Trail in Austin was the only other Texas trail honored with the designation.
National recreation trail designation recognizes existing trails and trail systems that link communities to recreational opportunities on public lands and in local parks. The national recreation trail program is jointly administered by the National Park Service and the USDA Forest Service in conjunction with a number of other federal and nonprofit partners, notably American Trails, which hosts the national recreation trails website at www.americantrails.org/nationalrecreationtrails.
The Leon Creek Greenway North, from Loop 1604 to Ingram Road, features 13 miles of trail among a variety of scenic and diverse natural landscapes that include pedestrian bridges, unique rock features and a large stand of cottonwood trees. The trails also feature connections to O.P. Schnabel Park, Bamberger Nature Park, Cathedral Rock Park, Pearsall Park, Earl Scott Pond, Rodriguez County Park, Wolff Stadium, the University of Texas at San Antonio (UTSA) and numerous adjacent neighborhoods and businesses.
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The Texas Trails Network recently awarded VIA Metropolitan Transit and the Parks and Recreation Department the Great Texas Trailhead Award at its annual state conference here in San Antonio.
The Great Trail Head Award is given to a public or private entity in recognition of innovative trail planning and design. The award honors the collaborative effort to develop a trailhead at the Ingram Transit Center to connect with the Leon Creek Greenway. The two agencies worked together after VIA acquired the land next to the busy transit center to make the tract accessible to trail riders on Leon Creek Greenway. Now the trailhead provides both transit riders and trail riders seamless access to passenger amenities such as restrooms, vending machines and customer service representatives.
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Oral history with Mr. Amzie Moore, Black civil rights worker This oral history is provided through a cooperative project of University of Southern Mississippi Libraries and USM's Center for Oral History and Cultural Heritage. Funding provided by a National Leadership Grant for Libraries from the Institute for Museum and Library Services The transcript is presented here for reference purposes only. Interviews in this collection are protected by copyright. PERMISSION TO PUBLISH MUST BE REQUESTED from the Center for Oral History and Cultural Heritage. Please call ( 601) 266- 4574 for more information. Biography Mr. Amzie Moore was born September 23rd, 1911, in rural Mississippi, on the county line of Carroll and Grenada Counties. He recalls that " grandfather died at 104. He'd been a slave, and was a very interesting character - couldn't read or write, yet he accumulated more than a section of land and had in the neighborhood of. . . twenty thousand dollars. . . saved when he died." Mr. Moore's young life was one of poverty, in spite of hard work, accompanied by a driving desire to gain an education. When his mother died in 1925, the parents were separated " so my father came and picked up the two smaller children, and at about fourteen I was on my own." Even when his family was together he recalls " we were always in trouble with our economy. I think that was the biggest problem because a lot of times we couldn't eat." Educational opportunities were very limited for black children in those days but Amzie Moore successfully completed high school. Although he did not realize his dream of gaining a college education, he was successful in making himself a self- educated man. In 1935, Mr. Moore took a job with the United States Post Office and served there until his retirement in 1968 - with three years, six months and eighteen days out to serve the country in the military during World War Two. Mr. Moore became an active worker for black civil rights, and concentrated his efforts on the right to vote for Negroes. His major goal has been to create a situation where black people can be economically self- sufficient and have decent lives. But he does not advocate separatism. He believes that if the American society is to survive, and avoid the fate suffered by such old civilizations as the ancient Roman Empire, all people should cooperate regardless of their race or creed. Mr. Moore lives in retirement in Cleveland, Mississippi, which has been his home for a half century. He is married and the father of several children. mus- coh. moorea. doc Page 1 of 61
Object Description
Title | Oral history with Mr. Amzie Moore, Black civil rights worker |
Description | Oral history.; Two interviews conducted on March 29 and April 13, 1977 with Mr. Amzie Moore at his home in Cleveland, Mississippi. Moore was born on September 23, 1911 in rural Mississippi, on the county line of Carroll and Grenada Counties. In 1935, he took a job with the United State Post Office and served there until his retirement in 1968. Moore became an active worker for African American civil rights and concentrated his efforts on the right to vote for African Americans. Another important goal for Moore was to help African Americans be economically self-sufficient and live happy, successful lives. Moore worked to build low cost housing for the poor African Americans and participated with the Head Start Program. |
Date of interview | 1977 March 29 (1st interview); 1977 April 13 (2nd interview) |
Interviewer | Garvey, Michael. |
Coverage (time period) | 1911-1977 (primarily 1940s-1960s) |
Resource type | Text |
Format | Digital reproduction of a 61-page document. |
Language | English |
Publisher |
University of Southern Mississippi. Center for Oral History and Cultural Heritage. University of Southern Mississippi Libraries. (electronic version) |
Contributors | Electronic version made available through a National Leadership Grant for Libraries from the Institute for Museum and Library Services. |
Notes | This item is part of the Civil Rights in Mississippi Digital Archive. |
Rights | Copyright protected. Use of materials from this collection beyond the exceptions provided for in the Fair Use and Educational Use clauses of the U.S. Copyright Law may violate federal law. Permission to publish or reproduce is required. |
Contributing institution | Mississippi Oral History Program of the University of Southern Mississippi. |
Digital repository | University of Southern Mississippi Digital Collections. |
Digital collection | Oral History. |
File size | 490.258 KB |
File extension | |
Identifier | mus-coh.moorea |
File name | mus-coh.moorea.pdf |


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2001The Handicap Awareness website was designed to inform you about people with disabilities. In our site you will learn how to read the Braille alphabet and use read the sign language alphabet. This site also provides suggestion on how you can assist people with handicapping conditions.About this site
2001The site contains a brief history of the handi-sports movement. A story from the life of one of the Ukrainian invalid sportsmen with his improvements and problems is placed here.About this site
2001Unlike other disabilities/handicaps, learning disabilities are invisible. Because of this, they often go undiagnosed. Undiagnosed Learning Disabled Kids are erroneously labeled lazy and unmotivated, and they suffer needlessly because they are punished for being off task, and for failing to demonstrate their obvious intelligence in their academic performance. This results in low self-esteem and depression due to their feelings of unworthiness caused by the knowledge that they are disappointing and hurting their parents. They find themselves incapable of doing anything to change that, and often end up believing that they are stupid. Feeling different at an age when they just want to fit in, they develop poor peer relations and often become academic or social dropouts. This site was created to avert such a disaster. In this virtual tree house, LD kids can learn more about their disabilities and discover ways in which they can help themselves. This information is available in text form, streaming audio, and via mobile phone through WAP technology. Kids can also receive immediate answers to their questions by asking "Dr. Doggy" - a cute and loveable internet artificial intelligence bot, and they can interact with each other and share their feelings via the multilingual message boards and chat room. Most importantly, they can meet others like themselves, develop friendships, talk about their hopes, dreams and goals and come to the realisation that they are not alone on their path of life.About this site
2001The website our team created and submitted presents information about the International Paralympic Games. Our site has 10 main links.About this site
2001Our project is about Special Needs schools in Cape Town.The aim of this topic is to let more people become aware of these disabilities and support the schools as well as become more supportive of the children that attend these schools.About this site
2000Our Web site is about being disabled and the lifestyle of a disabled teenager It would help a "normal" adult/child to relate to a disabled adult/child. Disabled children are not accepted easily into society and we hope that our Web site will try to explain to a "normal" person what a disabled person is all about. About this site
2000People with a handicap are limited to what they can do. That's why they often need help from other peole. Learn more about handicaps and how you can help people with a handicap.About this site
2000This site provides the viewer with a history of American Sign Language and shows how to make each of the letter signs. It also has brief biographical information about a couple of famous deaf people. About this site
2000Understanding Disablities describes the characteristics and causes of autism, deafness and blindess. There is also a special section on Helen Keller and a colorful finger-spelling chart. Part of nderstanding disabilities is realizing that people are more alike than they are different.About this site
2000Our site describes the many methods that blind people can use to lead productive lives. We wrote about a school for the blind, tools the blind use and guide dogs, as well as Braille. We wanted to show sighted students that the blind are not so different from them. We wanted to help people become more sensitive to the handicapped through a better understanding of their capabilities. About this site
1999American Sign Language for Kids will introduce children to sign language. The web page will teach about American Sign Language, deafness, how to sign letters, numbers, and words. We also have made activities for you to play once you have learned some sign language.About this site
1999We would like to tell other people about dyslexia. There are many people who have it and for a lot of people it is not exactly clear what is is, so we would like to tell them.About this site
1998"What Is It Like To Hear a Hand?" This is the question this wonderful web site tries to answer through its use of scientific information, comments, and letters from deaf people. The overall reason for this web site is to educate hearing people about deafness and the deaf community. The causes of deafness, what sign language is, and how to live with deafness are explained in full. An excellent resource for students and teachers. About this site
1997This introduction to the world of computers is divided into hardware, software, operating systems, and adaptive technology. Investigate different software types and operating systems, find out how scanners and modems work, and learn about the computer problems that face a person with disabilities. The site also gives a history of computational machines from the abacus to the Internet. Can you buy tokens to board an "expansion bus"? No, find out why at this site! About this site
1997Deaf communities are extremely tightly-knit worlds that exist to preserve friendships and facilitate interaction. Sign language can be very efficient and even people who come from different regions of the world are able to communicate using signs. Information on sign languages all over the world, and links to many informative sites, provide a window into deaf culture. About this site
1997This site is split into three main sections: Inclusion of hearing-impaired students into a normal school, Miscellaneous data that could support either side, and segregation of hearing-impaired students into special schools. About this site
1997This site help us understand how it is to be different. It succeeds beautifully with open and sensitive treatment of disability issues. Visual disabilities are the ones you can see, like cerebral palsy. Invisible ones, such as bulimia or ADD (Attention Deficit Disorder), also affect one's entire life. Simulations are offered to help you to step into another's shoes and imagine how your life would be if you were differently-abled. About this site


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Night blindness means having difficulty seeing in the dark or in low light. One of the most common issues with night blindness is difficulty driving in the evening or at night.
Night blindness is caused by a disorder of the cells in the retina that are responsible for vision in dim light (cones). There may be several common causes:
- Lack of vitamin A, which can cause a disorder of the retina
- Cataracts , which are cloudy areas in the lens of the eye
- Some forms of retinal degeneration, such as retinitis pigmentosa
- Certain medications
- Birth defects
Risk Factors
A risk factor is something that increases your chance of getting a disease or condition. Some risk factors for night blindness include:
- Age—elderly people are more likely to have cataracts
- Genetics—retinitis pigmentosa
- Diet: people who don't eat enough sources of vitamin A, such as green leafy vegetables, eggs, and whole milk products (vitamin A deficiency is very rare in the US, but still occurs in certain less developed countries)
Disorders that affect the ability of the body to absorb vitamin A:
- Liver disorders
- Surgery on the pancreas or liver
- Intestinal conditions
- Bowel surgery for obesity
- Glaucoma
- Diabetes
- Trouble adjusting from low levels of light to high levels of light
Symptoms are difficulty or inability to see in low light or darkness. While driving, this may also occur a few seconds after the bright headlights of an oncoming car have passed.
A doctor will give you a medical examination to determine the cause of your night blindness. Some of the things a doctor might do are:
- Ask detailed questions about your experience of night blindness
- Test the levels of vitamin A in your blood
- Give you an eye exam
Ask about your medical history, including:
- Diet
- Medications
- Use of corrective lenses
- Family history of diabetes
Depending on the reason for your night blindness, treatment will address the specific cause. Treatments generally include:
- Taking vitamin A supplements
- Having cataracts removed
- Low-vision aids
If you experience night blindness, it is important to take safety precautions, like not driving in the evening or at night.


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Canon BJ-220JS ink cartridges and inkjet refills
At Refill Bay, we offer a variety of inkjet refill options for your Canon BJ-220JS inkjet printer. Whether you want to refill your own inkjet cartridges with our refill kits and bulk printer ink, or whether you just want a cartridge that's ready for use, Refill Bay offers something for everybody! We offer the following products for your Canon BJ-220JS inkjet printer: |


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Created on 17 October 2012
- Description
Check out this exclusive preview of UNMASKED, the new documentary series from WolvesTV! The premier episode debuts on the broadcast and online later this mon...
- Unmasked Ep. 30: A Tale Of Two Cities
- (Media / Unmasked Ep. 30: A Tale Of Two Cities)
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Scott Arniel has been a head coach before. He knows how precarious a position it is, and how much of the change
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- Unmasked Ep. 28: Opposite Sides
- (Media / Unmasked Ep. 28: Opposite Sides)
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When the Wolves opened the season last October, Mike Davies and Zach Miskovic were on the bubble, working twice as
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- Unmasked Ep. 27: The Better Half
- (Media / Unmasked Ep. 27: The Better Half)
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When you've played professional hockey as long as Darren Haydar, you learn a thing or two. But each season brings
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Drag Specialties H4 Standard Halogen Replacement Bulbs Mark (Covington, WA) Fit Quality Installation Recommend H4 bulb Light bulb fit in fine and works good. Only had it in for a couple months so don't know how long it will last. So far so good. Read All Reviews Expand [+]Less [-]
Ricks Motorsport Electrics Stator Ann (Cheboygan, MI) Fit Quality Installation Recommend Great product with great customer service This stator for my 1998 Arctic Cat zr600 fit and works perfectly. I think something else is wrong with the sled because I went through 2 oem stators and then a Rick's stator in 2 years. The Rick's stator was better than oem and their customer service is superior. They are going out of their way with a technician to help me solve my problem. HIGHLY recommend Rick's stators. Read All Reviews Expand [+]Less [-]
Two Brothers Racing Muffler Repack Kit Robert (El Sobrante, CA) Fit Quality Installation Recommend Lots of Extra Comes with twice the packing I needed and lots of extra rivets. Instructions (for those that don't already know how to do it) are clear and very simple. This was my first repack and it went very easily. Also comes with the drill bit you need to drill out the old rivets. Great product, highly recommend it! Read All Reviews Expand [+]Less [-]
Tribal Whips 6' Nightstalker Xtreme LED Lighted Whip Timothy (Monahans, TX) Fit Quality Installation Recommend 6' Nightstalker Xtreme LED Lighted Tribal Whips 5 Stars in all 4 categories Read All Reviews Expand [+]Less [-]
Maxima Pre-Oiled Air Filter ryan (belton, SC) Fit Quality Installation Recommend perfect replacement The stock filter on a "borrowed" bike was shredded, so I bought and installed this on the CRF100. It was a PERFECT fit, nice and snug. Quality and amount of oil is perfect. I was a little deceived, not realizing this was not a total replacement filter, just a factory replacement to go over the stock metal mesh. I was thinking it was like a UNI with a plastic cage or something that replaced the metal part, but it wasn't. Still a good buy and no regrets! Read All Reviews Expand [+]Less [-]
BikeMaster Maintenance Free Battery Richard (Cottonwood Falls, KS) Fit Quality Installation Recommend Bikemaster MF Battery Delivered quick and fit was good for 1997 Kawasaki Vulcan 1500. One month rating for quality is a bit early. Install was uneventful. Thanks Motorcycle Superstore, you have become my go-to source for Honda, Harley, and Kawasaki motorcycle parts! Read All Reviews Expand [+]Less [-]


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Swanstone BS-1515037 Bone Entertainment and Bar Sink 15" W x 15" D
Item #:
Technical Specs
Installation Guide | |
Specification Sheet | |
ADA | No |
Apron Front | No |
Basin Depth | 5 |
Basin Length | 10 |
Basin Rack Included | No |
Basin Width | 10 |
Basket Strainer Included | No |
Cutting Board Included | No |
Drain Connection | 3.5 |
Drain Placement | Center |
Faucet Centers | 0 |
Faucet Hole Size | 1.375 |
Faucet Holes | 1 |
Faucet Included | No |
Height | 6 |
Installation Type | Drop In, Undermount |
Length | 15 |
Material | Engineered Stone |
Number Of Basins | 1 |
Product Weight | 10 |
Sink Shape | Square |
Soap Dispenser Included | No |
Sound Dampening | No |
Theme | Traditional |
Width | 15 |
Entertainment and Bar Sink 15" W x 15" D
Swanstone is a reinforced solid surface. Color and texture run all the way through and cannot wear away. Choose from a wide variety of easy-to-clean colors for your kitchen and bath. Products include kitchen sinks, bath and shower walls, shower floors, vanity tops and bowls. And, products made of Swanstone are covered by a limited lifetime warranty.
Swanstone BS1515 Features:
- Stylish and functional, a Swanstone drop-in sink is the perfect way to give your kitchen that distinctive edge Choose from a wide variety of sizes, shapes and colors for the perfect complement to your kitchen's decor
- Solid surface style in your entertainment space
- 6" (152mm) deep bowl
- Renewable surface will not wear away
- Hot pots & boiling water will not harm
- Highest resistance of impact from heavy objects
- Easily accommodates all faucet styles
- Heat, stain, and scratch resistant for lasting beauty
- All Swanstone drop-in kitchen sinks can also be installed as undermount
Additional Swanstone Links
- Shop All Swanstone Products
- Shop All Swanstone Swanstone Kitchen Sinks Collection Products
Our SKU: BS1515
This product is listed under the following manufacturer number(s):
Acorn - BS1515046
Almond Galaxy - BS1515035
Arctic Granite - BS1515168
Babys Breath - BS1515040
Bermuda Sand - BS1515018
Bisque - BS1515015
Black Galaxy - BS-1515037
Bone - BS1515124
Canyon - BS1515169
Caraway Seed - BS1515126*
Cloud Bone - BS1515125*
Cloud White - BS1515063
Cornflower - BS1515044*
Country Blue Granite - BS1515024*
Dovegray - BS1515121
Glacier - BS1515042
Gray Granite - BS1515061
Ironweed - BS1515045*
Mocha Galaxy - BS1515012
Night Sky - BS1515122
Prairie - BS1515023*
Prairie Clover - BS1515064
Purple Sage - BS1515043*
Rose Granite - BS1515062*
Sawgrass - BS1515031*
Shell Rose - BS1515056
Tahiti Blue - BS1515050
Tahiti Desert - BS1515057
Tahiti Evergreen - BS1515053
Tahiti Gray - BS1515059
Tahiti Ivory - BS1515058
Tahiti Matrix - BS1515052
Tahiti Rose - BS1515051
Tahiti Sand - BS1515055
Tahiti Terra - BS1515011
Tahiti White - BS1515010
White - BS1515022
Wild Indigo - BS1515060
Winter Wheat
*Denotes a finish or option that has been discontinued
2 Questions from the Community
Can this sink support a garbage disposal?
Does this sink come with the faudet or drain basket shown in the picture?
Product Reviews
Swanstone Corporate Statement
For more than four decades, we have been a quiet leader in the kitchen and bath industry. Our high-quality products have always balanced durability, value and style. Innovation is one of our core values, and we have set a standard with our ability to invent. Now it's time to reinvent.
The Swan Story
For more than 40 years, we've been creating innovative and affordable solid surface products and materials for customers all over the world. It started in 1964, when we introduced the Swan Shell Shower, a doorless, shell-shaped shower that captured the spirit of its time.
The Shell Shower was the first in a long line of original kitchen and bath products from Swan, including the Circle Shower as well as the industry's first non-ceramic tile bathtub wall system.
In 1987, we introduced Swanstone to the world, first with a line of vanity tops and bowls. Swanstone quickly became known for its superior impact strength, heat resistance, and ability to resist scratches and stains. Consumers now had an elegant and durable solid surface material that was also affordable.
Since then, our Swanstone line has expanded to include a wide variety of kitchen sinks, countertops, tub and shower walls, and more. In 1994 we introduced the Swanstone 1/4" sheet program, offering even more flexibility to Swanstone customers. In 1997 we introduced a complete line of Swanstone products for the restaurant industry, including tabletops, countertops, vanity tops, mop service sinks and windowsills.
At Swan, we're committed to a policy of continuous improvement, to providing our customers with the highest quality products and most responsive customer service in the kitchen & bath industry. And we stand behind this commitment with some of the best warranties in the business.
Made in America
The Swan Corporation is headquartered in St. Louis, Missouri, with manufacturing facilities in Centralia, Illinois.
We proudly manufacture all products made from these material systems in the USA.
Swan High-Gloss
Swanstone Swanstone Kitchen Sinks Collection
Swanstone Kitchen Sinks come in Classic Styles and Designs, with a renewable surface that will not wear away. Hot pots and Boiling water will not harm these Swanstone Sinks that are known industry wide for their resilience and resitance to scratching and chipping. These sinks will easily accomodate any faucet style.
Other Products In The Swanstone Swanstone Kitchen Sinks Collection
Swanstone KSDB-2518
Space-Saver Double Basin Swanstone Kitchen Sink 25" W x 18" D
$146.00$116.80(3) -
Swanstone KSSB-3322
Kitchen Sink Single Basin Swanstone 33" W x 22" D
$319.00$255.20(8) -
Swanstone KSTB-4422
Kitchen Sink Triple Basin with Two Large and One Small Bowls
$388.00$310.40(2) -
Swanstone KSDB-3322
Kitchen Sink Double Basin 33" W x 22" D
$269.00$215.20(1) -
Swanstone US-2215
Kitchen Sink Single Bowl Undermount Swanstone 25" W x 21.25" D


text:
- Musician's Friend Best Selection, Price & Service. Guaranteed.
Need Help? Ask our Experts or call 800-449-9128
Private Reserve Guitars 866-926-1923
Need Help? Ask our Experts or call 800-449-9128
Designed for beginning players, these strings are ideal for Piezo and magnetic pickups.
The D'Addario Prelude viola strings feature a solid steel core string that is excellent for students and amateur players. Durable Prelude strings are not affected by temperature and humidity changes. Prelude strings are bright, without the shrill sound of traditional steel strings, and are easy to bow. Great for classical, modern, jazz, and country music.
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Our product catalog varies by country due to manufacturer restrictions. If you change the Ship-To country, some or all of the items in your cart may not ship to the new destination.


text:
Black Label Ring
The golden dome glitters for any occasion.
- Individual style. Clean, modern lines. The exclusive Black Label by Chico's™ collection.
- Adjustable.
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Miller Syncrowave 250 DX TIG/Stick Welder (907194)
Great for heavy industrial applications. Learn MoreRegular Price: $3,908.00
Special Price: $3,099.00
Miller Syncrowave 250 DX TIG/Stick Runner Welder Complete (951117)
Running gear included with this package. Learn MoreRegular Price: $6,440.00
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text:
Criolo has canceled his upcoming US tour due to an unforeseen delay with the release of his new album.
David Gordon Green returns to the Wex on Sat, Mar 29 to introduce his latest feature, Joe, in a special member-only screening.
Cruzamentos: Contemporary Art in Brazil
Rosângela Rennó Vera Cruz
The Hills of Disorder


text:
Events and Public Programs
Works on Long-term View
Visitor Information
Tours and School Groups
Community Free Day
About Dia:Beacon
Support Dia:Beacon
Joseph Beuys, 7000 Oaks
Walter De Maria, The New York Earth Room
Walter De Maria, The Broken Kilometer
Dan Flavin, untitled, 1996
Max Neuhaus, Times Square
Walter De Maria, The Lightning Field
Walter De Maria, The Vertical Earth Kilometer
The Dan Flavin Art Institute
Robert Smithson, Spiral Jetty
George Trakas, Beacon Point
Program Calendar
Artists on Artists Lecture Series
Discussions in Contemporary Culture
Dance and Performance Series
Gallery Talks
Readings in Contemporary Poetry
Ian Wilson / Discussions
Education Programs
Arts Education Program at Dia:Beacon
Arts Education Program at Dia:Chelsea
Daniel Lefcourt, Modeler
Laylah Ali, John Brown Song!
Shannon Ebner, Language Is Wild
Sue Tompkins, My Kind Book
Dia Publications
Dia Bookshop and Diabooks.org
Support Dia
Make a Gift
Join a Dia Council
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Stay Connected
Dia:Beacon Spring Benefit
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About Dia
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Dia x CUP Teen Urban Investigation on Museums
Lisa Nelson and Steve Paxton
Yvonne Rainer
Antoni Tàpies Film Program
Artist Walkthroughs of Palermo Retrospective
Black Popular Culture
Constructing Masculinity
Conversations and Lectures
Critical Fictions
Democracy: A Project by Group Material
Discussions in Contemporary Culture #1
Ideologies of Technology
If You Lived Here…
James Benning Film Program
Joan Jonas: The Shape, the Scent, the Feel of Things
Lives of Performers: Art, Film, Performance Around 1970
Merce Cunningham Dance Company: Beacon Events
Readings in Contemporary Literature
Remaking History
Robert Lehman Lecture Series at Dia:Chelsea
Robert Whitman, Passport
Robert Whitman: Prune Flat (1965) and Light Touch (1976)
St. Luke's Chamber Ensemble
Stars Don't Stand Still in the Sky
The Work of Andy Warhol
Trisha Brown Dance Company Performance Series
Tuesdays on the Terrace
Vision and Visuality
Visual Display


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- Movie length : 8:25
Featured model : Japanese AV Model
Amazing Japanese AV hottie in fancy dark pantyhose arranges a really hardcore sex play with her horny partner. The cutie makes a footjob and starts to rub his hairy body, stimulating his dick at the same time, and toying in his ass with toys, and then she fucks his ass hard with strap-on!
- 100%
- Movie size : 831 Mb
- Movie length : 26:43
Gorgeous Japanese mature lady Julia looks so sexy when she is hot. Her horny lover likes her amazing body with big bubbles and he rips her pantyhose in ecstasy to fuck her naughty pussy. The skinny model feels so well and enjoys this rough banging, getting hot cum on her pretty face!
- 83%
- Movie size : 727 Mb
- Movie length : 28:42
Savoury Japanese cutie Asahi Mizuno poses in front of her boyfriend in sexy lingerie. She looks really gorgeous in her nylon stockings, and her lover fondles her lovely body and licks her pussy.The girl gets hot and starts to jerk off this hard boner and to suck it in 69 position.
Japanese babe with nice ass Asahi Mizuno enjoys slit teasing
- 83%
- Movie size : 620 Mb
- Movie length : 20:36
This massage session is surely gonna end up in a dirty manner! Our nice teen babe in sexy lingerie Kurumi Kino knows that perfectly and that excites her even more! That´s why she endures cock sucking and dick riding with so much of burning pussy passion!
- 75%
- Movie size : 939 Mb
- Movie length : 58:42
Sex appeal Japanese teen cutie Rina Itou with beautiful body and nice smooth ass gets teased hard by horny mature dudes. These nasty guys fondle her lovely juicy body greedily and lick her neat shaved pussy. They hammer her juicy slit mercilessly in different kinky positions and she gets a huge facial!
- 100%
- Movie size : 1 Gb
- Movie length : 48:07
Stunning Japanese teen gal Kimika Ichijou and her juicy female friend are involved into a kinky group action. The beauties with sweet sexy bodies and insatiable mouths share cock, giving outstanding blowjobs, and arrange a nasty foursome fuck, getting their mouths full of cum!
- 100%
- Movie size : 1 Gb
- Movie length : 41:01
Sexy japanese teacher Chihiro Akino is made to kneel and suck huge cock during nasty oral session at school along horny student. naughty milf loves feeling huge cock in her mouth and likes gagging like a true pornstar. She is insatiable when it comes to a hard cock!
- 67%
- Movie size : 486 Mb
- Movie length : 12:25
Alluring Japanese milf Natsumi Shiraishi with lovely juicy body and hot medium-sized tits experiences hardcore body teasing. Her perverted guy turns on making his girlfriends enslaved. Getting a fancy chain on her neck, the milf pleases the guy with perfect blowjob and hardcore cock riding!
Enchanting Asian beauty Natsumi Shiraishi in hardcore action
- 56%
- Movie size : 593 Mb
- Movie length : 37:13
Attractive short-haired Japanese teen Riku Minato is involved to a hardcore threesome sex play by two horny mature dudes. She takes a bath with them in her school uniform and now she starts to look even more sexy in her wet clothes. She gives double blowjob and enjoys teasing by sex toys, and then gets her mouth and pussy fucked hard!
- 100%
- Movie size : 1 Gb
- Movie length : 41:32
Lustful office babe Chika Haruno flirts with her sexy colleague, and seduces him for sex. She opens her legs to enjoys pussy licking.The naughty seductress enjoys getting her hairy pussy stretched and fingered, and the horny guy stuffs her mouth with his throbbing schlong.
- 89%
- Movie size : 743 Mb
- Movie length : 23:01
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Dark Antique Gold Mirror
More than 50 years ago Feiss began by offering a small assortment of porcelain figurine lamps, they were topped with his Mother's hand sewn lampshades.
Today at Feiss we are pleased to offer a full line of interior and exterior residential lighting and lamps.
Beautiful Design and Exceptional Quality have been hallmarks of Feiss since the beginning. From the initial sketches to the finished product each step is equally important and overseen by a team of dedicated lighting professionals.
Whatever your look is, you will find it at Feiss. Furnish both the interior and exterior of your home with exquisite lighting at a variety of price points to fit any budget and satisfy your personal design expression . We source quality metals, crystal, marble, ceramics and yes porcelain as well as many other materials to achieve distinctive looks across all of our offerings.
Our customers are second to none and our dedication to them matches that. We take delight in offering exceptional customer care and strive to exceed customer expectations each and every time.
With pride in our company's past and a commitment to the future, employees from Coast to Coast and from across the Globe all work together to deliver the very best in lighting and service.
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